Data from: Gut microbiota regulate motor deficits and neuroinflammation in a model of Parkinson’s disease

Sampson TR, Debelius JW, Thron T, Janssen S, Shastri GG, Ilhan ZE, Challis C, Schretter CE, Rocha S, Gradinaru V, Chesselet M, Keshavarzian A, Shannon KM, Krajmalnik-Brown R, Wittung-Stafshede P, Knight R, Mazmanian SK

Date Published: February 17, 2017

DOI: http://dx.doi.org/10.5061/dryad.4mp6h

 

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Title HumanizedMotorFunction
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Description Motor function scores of wild-type and Thy1-aSyn mice colonized with fecal microbes derived from Parkinson's disease patients or matched healthy controls.
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Title MouseTreatmentMotorFunction
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Description Motor function scores of wild-type and Thy1-aSyn mice, under differing microbial colonization status. Conventionally colonized, germ-free, antibiotic-treated, recolonized germ-free, and short-chain fatty acid treated animals.
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Title SynucleinandInflammation
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Description Expression and production of alpha-synuclein and proinflammatory cytokines, and microglia diameter and cytokine expression in the brain of wild-type and Thy1-aSyn mice, under specific pathogen free and germ-free conditions.
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When using this data, please cite the original publication:

Sampson TR, Debelius JW, Thron T, Janssen S, Shastri GG, Ilhan ZE, Challis C, Schretter CE, Rocha S, Gradinaru V, Chesselet M, Keshavarzian A, Shannon KM, Krajmalnik-Brown R, Wittung-Stafshede P, Knight R, Mazmanian SK (2016) Gut microbiota regulate motor deficits and neuroinflammation in a model of Parkinson’s disease. Cell 167(6): 1469-1480. http://dx.doi.org/10.1016/j.cell.2016.11.018

Additionally, please cite the Dryad data package:

Sampson TR, Debelius JW, Thron T, Janssen S, Shastri GG, Ilhan ZE, Challis C, Schretter CE, Rocha S, Gradinaru V, Chesselet M, Keshavarzian A, Shannon KM, Krajmalnik-Brown R, Wittung-Stafshede P, Knight R, Mazmanian SK (2016) Data from: Gut microbiota regulate motor deficits and neuroinflammation in a model of Parkinson’s disease. Dryad Digital Repository. http://dx.doi.org/10.5061/dryad.4mp6h
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