Data from: Quantitative detection of rare interphase chromosome breaks and translocations by high-throughput imaging

Burman B, Misteli T, Pegoraro G

Date Published: August 4, 2015

DOI: http://dx.doi.org/10.5061/dryad.6h7nt

 

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Title Readme
Description Readme file.
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Title Acapella_Scripts_Parameters
Description This zipped file contains the Acapella script used to analyze all the image datasets and the Acapella parameters files for each analysis session. The parameters files are named according to the relative image dataset analyzed.
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Title R_Analysis_Fig3_6
Description This zipped file contains the The the .txt single-object level image analysis results files generated by Acapella, the .Rmd R script used for the analysis and the .html R output file. This .Rmd R script was used to generate Fig. 3 - 6 of the article.
Download R_Analysis_Fig3_6.zip (117.4 Mb)
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Title R_Analysis_FigS1
Description This zipped file contains the The the .txt single-object level image analysis results files generated by Acapella, the .Rmd R script used for the analysis and the .html R output file. This .Rmd R script was used to generate Fig. S1 of the article.
Download R_Analysis_FigS1.zip (150.1 Mb)
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Title BC_140819_M2A_GFP_ALK_UN
Description This zipped file contains the image dataset relative to Untreated Mac2A cells stained with the hiBA-ALK probe set. This dataset was used to generate Fig. 3 - 6 of the article.
Download BC_140819_M2A_GFP_ALK_UN.zip (640.2 Mb)
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Title BC_140713_K299_K299_ALK_UN
Description This zipped file contains the image dataset relative to Untreated K299 cells stained with the hiBA-ALK probe set. This dataset was used to generate Fig. 3 - 6 of the article.
Download BC_140713_K299_K299_ALK_UN.zip (532.3 Mb)
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Title BC_140713_K299_K299_NPM_UN
Description This zipped file contains the image dataset relative to Untreated K299 cells stained with the hiBA-NPM1 probe set. This dataset was used to generate Fig. 3 - 6 of the article.
Download BC_140713_K299_K299_NPM_UN.zip (530.7 Mb)
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Title BC_140815_M2A_GFP_ALK_IR
Description This zipped file contains the image dataset relative to Irradiated (25 Gy) Mac2A cells stained with the hiBA-ALK probe set. This dataset was used to generate Fig. 3 - 6 of the article.
Download BC_140815_M2A_GFP_ALK_IR.zip (1.420 Gb)
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Title BC_140815_M2A_GFP_NPM_IR
Description This zipped file contains the image dataset relative to Irradiated (25 Gy) Mac2A cells stained with the hiBA-NPM1 probe set. This dataset was used to generate Fig. 3 - 6 of the article.
Download BC_140815_M2A_GFP_NPM_IR.zip (1.401 Gb)
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Title BC_140819_M2A_GFP_NPM_UN
Description This zipped file contains the image dataset relative to Untreated Mac2A cells stained with the hiBA-NPM1 probe set. This dataset was used to generate Fig. 3 - 6 of the article.
Download BC_140819_M2A_GFP_NPM_UN.zip (1.256 Gb)
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Title BC_150527_K299_ZERO_ALK_UN
Description This zipped file contains the image dataset relative to 0% Untreated K299 cells (100% Mac2A cells) stained with the hiBA-ALK probe set. This dataset was used to generate Fig. S1 of the article.
Download BC_150527_K299_ZERO_ALK_UN.zip (1.430 Gb)
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Title BC_150527_K299_POINTONE_ALK_UN
Description This zipped file contains the image dataset relative to 0.1% Untreated K299 cells stained with the hiBA-ALK probe set. This dataset was used to generate Fig. S1 of the article.
Download BC_150527_K299_POINTONE_ALK_UN.zip (1.469 Gb)
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Title BC_150527_K299_POINTFIVE_ALK_UN
Description This zipped file contains the image dataset relative to 0.5% Untreated K299 cells stained with the hiBA-ALK probe set. This dataset was used to generate Fig. S1 of the article.
Download BC_150527_K299_POINTFIVE_ALK_UN.zip (1.541 Gb)
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Title BC_150527_K299_ONE_ALK_UN
Description This zipped file contains the image dataset relative to 1% Untreated K299 cells stained with the hiBA-ALK probe set. This dataset was used to generate Fig. S1 of the article.
Download BC_150527_K299_ONE_ALK_UN.zip (1.608 Gb)
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Title BC_150527_K299_TEN_ALK_UN
Description This zipped file contains the image dataset relative to 10% Untreated K299 cells stained with the hiBA-ALK probe set. This dataset was used to generate Fig. S1 of the article.
Download BC_150527_K299_TEN_ALK_UN.zip (1.487 Gb)
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Title BC_150527_K299_HUNDRED_ALK_UN
Description This zipped file contains the image dataset relative to 100% Untreated K299 cells stained with the hiBA-ALK probe set. This dataset was used to generate Fig. S1 of the article.
Download BC_150527_K299_HUNDRED_ALK_UN.zip (1.434 Gb)
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When using this data, please cite the original publication:

Burman B, Misteli T, Pegoraro G (2015) Quantitative detection of rare interphase chromosome breaks and translocations by high-throughput imaging. Genome Biology 16: 146. http://dx.doi.org/10.1186/s13059-015-0718-x

Additionally, please cite the Dryad data package:

Burman B, Misteli T, Pegoraro G (2015) Data from: Quantitative detection of rare interphase chromosome breaks and translocations by high-throughput imaging. Dryad Digital Repository. http://dx.doi.org/10.5061/dryad.6h7nt
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