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Data from: Serological evidence of lyssaviruses among bats on southwestern Indian Ocean islands

Mélade, Julien, Centre de Recherche et de Veille sur les Maladies Emergentes dans l’Océan Indien, University of La Réunion, Institut de Recherche pour le Développement
McCulloch, Stewart, University of Pretoria
Ramasindrazana, Beza, Centre de Recherche et de Veille sur les Maladies Emergentes dans l’Océan Indien, University of La Réunion, Institut de Recherche pour le Développement, Institut Pasteur de Madagascar
Lagadec, Erwan, Centre de Recherche et de Veille sur les Maladies Emergentes dans l’Océan Indien, University of La Réunion, Institut de Recherche pour le Développement
Turpin, Magali, Centre de Recherche et de Veille sur les Maladies Emergentes dans l’Océan Indien, University of La Réunion, Institut de Recherche pour le Développement
Pascalis, Hervé, Centre de Recherche et de Veille sur les Maladies Emergentes dans l’Océan Indien, University of La Réunion, Institut de Recherche pour le Développement
Goodman, Steven M., Field Museum of Natural History
Markotter, Wanda, University of Pretoria
Dellagi, Koussay, Centre de Recherche et de Veille sur les Maladies Emergentes dans l’Océan Indien, University of La Réunion, Institut de Recherche pour le Développement
Published Jul 25, 2017 on Dryad. https://doi.org/10.5061/dryad.gp4h2

Cite this dataset

Mélade, Julien et al. (2017). Data from: Serological evidence of lyssaviruses among bats on southwestern Indian Ocean islands [Dataset]. Dryad. https://doi.org/10.5061/dryad.gp4h2

Abstract

We provide serological evidence of lyssavirus circulation among bats on southwestern Indian Ocean (SWIO) islands. A total of 572 bats belonging to 22 species were collected on Anjouan, Mayotte, La Réunion, Mauritius, Mahé and Madagascar and screened by the Rapid Fluorescent Focus Inhibition Test for the presence of neutralising antibodies against the two main rabies related lyssaviruses circulating on the African continent: Duvenhage lyssavirus (DUVV) and Lagos bat lyssavirus (LBV), representing phylogroups I and II, respectively. A total of 97 and 42 sera were able to neutralise DUVV and LBV, respectively. No serum neutralised both DUVV and LBV but most DUVV-seropositive bats (n = 32/220) also neutralised European bat lyssavirus 1 (EBLV-1) but not Rabies lyssavirus (RABV), the prototypic lyssavirus of phylogroup I. These results highlight that lyssaviruses belonging to phylogroups I and II circulate in regional bat populations and that the putative phylogroup I lyssavirus is antigenically closer to DUVV and EBLV-1 than to RABV. Variation between bat species, roost sites and bioclimatic regions were observed. All brain samples tested by RT-PCR specific for lyssavirus RNA were negative.

Usage notes

Mélade et al PLOS ONE 2016 database

Neutralizing antibody titers recorded for each bat serum sample tested
Melade_etal_PLOSONE_2016_database.xlsx