Data from: Phosphorescence monitoring of hypoxic microenvironment in solid-tumors to evaluate chemotherapeutic effects using the hypoxia-sensitive iridium (III) coordination compound

Zeng Y, Liu Y, Shang J, Ma J, Wang R, Deng L, Guo Y, Zhong F, Bai M, Zhang S, Wu D

Date Published: March 23, 2015

DOI: http://dx.doi.org/10.5061/dryad.pb7j7

 

Files in this package

Content in the Dryad Digital Repository is offered "as is." By downloading files, you agree to the Dryad Terms of Service. To the extent possible under law, the authors have waived all copyright and related or neighboring rights to this data. CC0 (opens a new window) Open Data (opens a new window)

Title Figure 2b
Description Figure 2b. The relationship between the pO2 and phosphoresce intensity.
Download Figure 2b.xls (18.43 Kb)
Details View File Details
Title Figure 2c
Description Figure 2c. Cytotoxicity evaluation of BTP: Trypan blue dye exclusion assay to measure the cell necrosis rate and Hoechst 33342 plus propidium iodide (PI) assay to measure the cell apoptosis rate (n=10).
Download Figure 2c.xls (23.04 Kb)
Details View File Details
Title Figure 4a
Description Figure 4a. The growth curves of CT-26 xenografts after transplantation into BALB/c nude mice treated with saline and cisplatin (n=6).
Download Figure 4a.xls (18.43 Kb)
Details View File Details
Title Figure 4b
Description Figure 4b. The phosphorescence intensity of tumor imaging of CT-26 xenografts after transplantation into BALB/c nude mice treated with saline and cisplatin (n=6).Saline (100 µL) or cisplatin (1 mg/kg, 100 µL).
Download Figure 4b.xls (21.50 Kb)
Details View File Details
Title Figure 4c
Description Figure 4c. The quantitative data curves of immunohistochemical stain of HIF-1a in tumor-bearing mice treated with saline and cisplatin, respectively (n=3).
Download Figure 4c.xls (18.43 Kb)
Details View File Details
Title Figure 4d
Description Figure 4d. The quantitative data curves of immunohistochemical stain of VEGFin tumor-bearing mice treated with saline and cisplatin, respectively (n=3).
Download Figure 4d.xls (18.43 Kb)
Details View File Details
Title Figure S1
Description Figure S1. The phosphorescence intensity of tumor imaging of CT-26 xenografts after transplantation into BALB/c nude mice treated with saline and cisplatin with different dose or combined drug treatment. Saline (100 µL),cisplatin (3 mg/kg, 100 µL), anti-VEGF (5 mg/kg, 100µL) or combination (cisplatin 3 mg/kg+anti-VEGF 5 mg/kg, 100 µL).
Download Figure S1.xls (22.52 Kb)
Details View File Details

When using this data, please cite the original publication:

Zeng Y, Liu Y, Shang J, Ma J, Wang R, Deng L, Guo Y, Zhong F, Bai M, Zhang S, Wu D (2015) Phosphorescence monitoring of hypoxic microenvironment in solid-tumors to evaluate chemotherapeutic effects using the hypoxia-sensitive iridium (III) coordination compound. PLOS ONE 10(3): e0121293. http://dx.doi.org/10.1371/journal.pone.0121293

Additionally, please cite the Dryad data package:

Zeng Y, Liu Y, Shang J, Ma J, Wang R, Deng L, Guo Y, Zhong F, Bai M, Zhang S, Wu D (2015) Data from: Phosphorescence monitoring of hypoxic microenvironment in solid-tumors to evaluate chemotherapeutic effects using the hypoxia-sensitive iridium (III) coordination compound. Dryad Digital Repository. http://dx.doi.org/10.5061/dryad.pb7j7
Cite | Share
Download the data package citation in the following formats:
   RIS (compatible with EndNote, Reference Manager, ProCite, RefWorks)
   BibTex (compatible with BibDesk, LaTeX)

Submissions have been temporarily disabled.

Search for data

Be part of Dryad

We encourage organizations to: