Data from: Identification and evaluation of novel acetolactate synthase inhibitors as antifungal agents

Richie DL, Thompson KV, Prindle V, Aust T, Riedl R, Tao J, Sexton JA, Zabawa T, Drumm J, Cotesta S, Eichenberger J, Schuierer S, Hartmann N, Movva NR, Tallarico JA, Ryder NS, Hoepfner D

Date Published: April 4, 2013

DOI: http://dx.doi.org/10.5061/dryad.qb753

 

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Title Supplemental_Data.zip
Downloaded 43 times
Description The compressed Supplemental_Data.zip archive contains two files: 1. Supplemental Data_S3, the complete HIP HOP profiles are provided as tab delimited .txt files. The sensitivity and z-scores for all HIP strains present in the pool across all tested compounds are listed in the HIP-exp-scores-annotation.txt file, scores for all HOP strains present in the pool are listed in the HOP-exp-scores-annotation.txt file. To reproduce the plots depicted in the article the sensitivity can be plotted on the y-axis, the z-score on the x-axis. Each gene is annotated with systematic name, common name, description, GO category etc. 2. The Supplemental_Data_S4.zip file containing the in silico docking solution. It is provided as a standard Protein Data Bank file named 1N0H_compound1_docked.pdb. UNK1 refers to the docked compound 1, all other structures are labeled as in the original 1N0H.pdb file downloaded from RCSB protein databank www.pdb.org.
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When using this data, please cite the original publication:

Richie DL, Thompson KV, Struder C, Prindle V, Aust T, Riedl R, Estoppy D, Tao J, Sexton JA, Zabawa T, Drumm J, Cotesta S, Eichenberger J, Schuierer S, Hartmann N, Movva NR, Tallarico JA, Ryder NS, Hoepfner D (2013) Identification and evaluation of novel acetolactate synthase inhibitors as antifungal agents. Antimicrobial Agents and Chemotherapy 57(5): 2272-2280. http://dx.doi.org/10.1128/AAC.01809-12

Additionally, please cite the Dryad data package:

Richie DL, Thompson KV, Prindle V, Aust T, Riedl R, Tao J, Sexton JA, Zabawa T, Drumm J, Cotesta S, Eichenberger J, Schuierer S, Hartmann N, Movva NR, Tallarico JA, Ryder NS, Hoepfner D (2013) Data from: Identification and evaluation of novel acetolactate synthase inhibitors as antifungal agents. Dryad Digital Repository. http://dx.doi.org/10.5061/dryad.qb753
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