Data from: Drosophila studies support a role for a presynaptic synaptotagmin mutation in a human congenital myasthenic syndrome

Shields MC, Bowers MR, Fulcer MM, Bollig MK, Rock PJ, Sutton BR, Vrailas-Mortimer AD, Lochmüller H, Whittaker RG, Horvath R, Reist NE

Date Published: September 28, 2017

DOI: https://doi.org/10.5061/dryad.st621

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Title Fig2C_Blot3
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Description Original blot used to quantify Fig2C
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Title Fig2C Blot2
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Title Fig2C_Blot1
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Title Fig2B_Blot2
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Title Fig2B_Blot1
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Title Fig2A_Blot2
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Title Fig2A_Blot1
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Description Original blot to quantify Fig2A
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Title Fig2_2A
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Description Raw data values for Fig2A quantification
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Title Fig2_2B
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Description Raw data values for quantification of Fig2B
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Title Fig2_2C
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Description Raw data values for Fig2C quantification
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Title Fig3_Fig 3 A,B
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Description Raw counts and percentages for lifespan of both control and experimental adult flies. Figure 3.
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Title Fig4_4B Control
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Description Raw response amplitudes per fiber for control evoked responses. Figure 4B.
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Title Fig4_4B P-L
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Description Raw response amplitudes per fiber for experimental genotype evoked responses. Figure 4B.
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Title Fig4_4B STATS
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Description Statistical analysis for Fig4B
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Title Fig4_4D
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Description Raw data values and statistical analysis for Fig 4D
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Title Fig4_4E
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Description Raw data values and statistical analysis for Fig4E.
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Title Fig5_5A
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Description Raw data values and statistical analysis for Fig5A.
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Title Fig5_5B
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Description Raw data values for Fig5B.
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Title Fig5_5C
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Description Raw data values and statistical analysis for Fig5C.
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Title Fig5_5D
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Description Raw data values and statistical analysis for Fig5D.
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Title Fig6_6B Control
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Description Raw and normalized data values for control in Fig6B.
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Title Fig6_6B P-L
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Description Raw and normalized data values for experimental gentoype in Fig6B.
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Title Fig7_7B Control
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Description Raw and normalized data values for control in Fig7B.
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Title Fig7_7B P-L
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Description Raw and normalized data values for experimental gentoype in Fig7B.
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Title Fig8_8C Male control averages
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Description Raw data values and averages for control in Fig8C
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Title Fig8_8C Male P-L averages
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Description Raw data values and averages for experimental genotype in Fig8C
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Title Fig8_8A Female Control averages
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Description Raw data values and averages for control in Fig8A
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Title Fig8_8A Female P-L averages
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Description Raw data values and averages for experimental genotype in Fig8A
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Title Fig8_8B TTEST
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Description Raw data and statistical analysis for Fig8B
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Title Fig8_8D TTEST
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Title Fig9 Fig9A-B
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Description Raw values and averages for Fig 9A-B
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Title Fig9_Binning
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Description Averages for Fig 9 binned into 1-minute intervals
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When using this data, please cite the original publication:

Shields MC, Bowers MR, Fulcer MM, Bollig MK, Rock PJ, Sutton BR, Vrailas-Mortimer AD, Lochmüller H, Whittaker RG, Horvath R, Reist NE (2017) Drosophila studies support a role for a presynaptic synaptotagmin mutation in a human congenital myasthenic syndrome. PLOS ONE 12(9): e0184817. https://doi.org/10.1371/journal.pone.0184817

Additionally, please cite the Dryad data package:

Shields MC, Bowers MR, Fulcer MM, Bollig MK, Rock PJ, Sutton BR, Vrailas-Mortimer AD, Lochmüller H, Whittaker RG, Horvath R, Reist NE (2017) Data from: Drosophila studies support a role for a presynaptic synaptotagmin mutation in a human congenital myasthenic syndrome. Dryad Digital Repository. https://doi.org/10.5061/dryad.st621
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