SNP genotypes for healthy and CIM-affected GSDs

Clark, Leigh Anne, Clemson University, https://orcid.org/0000-0001-6621-9660

Bell, Sarah, Clemson University

Evans, Jacquelyn, Clemson University

Evans, Katy, University of Nottingham

Tsai, Kate, Clemson University

Noorai, Rooksana, Clemson University

Famula, Thomas, University of California, Davis

Holle, Dolores, The Seeing Eye Inc.

lclark4@clemson.edu

Published Feb 10, 2022 on Dryad. https://doi.org/10.5061/dryad.f7m0cfxz3

Cite this dataset

Clark, Leigh Anne et al. (2022). SNP genotypes for healthy and CIM-affected GSDs [Dataset]. Dryad. https://doi.org/10.5061/dryad.f7m0cfxz3

Abstract

German shepherd dogs (GSDs) are predisposed to an inherited motility disorder of the esophagus, termed congenital idiopathic megaesophagus (CIM), in which swallowing is ineffective and the esophagus is enlarged. Affected puppies are unable to properly pass food into their stomachs and consequently regurgitate their meals and show a failure to thrive, often leading to euthanasia. Here, we generated genome-wide SNP profiles for healthy and CIM-affected GSDs using the Illumina CanineHD BeadChip, containing 220,853 SNPs.