Behavioral and ephys data of research paper: Microsecond interaural time difference discrimination restored by cochlear implants after neonatal deafness
Data files
Jan 19, 2021 version files 30.46 GB
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AcuteCI_ITDsingleClickExperimentsForAnalysis.csv
4.62 KB
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behaviorData.zip
739.07 KB
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CI_rat_ITD_ephys_data.zip
30.46 GB
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initialEphysAnalysis.m
9.07 KB
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psychModelsV1.py
15.49 KB
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psychometricFigure_eLife_fromNatCom.py
11.12 KB
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RasterAndTuningCurvesND_SNRanalysis.m
7.13 KB
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rasterPlotF32data.m
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SNRhistogramHancockvsND_SNRanalysis.m
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Abstract
The uploaded raw behavioral and electrophysiological data form the basis for our research study on "Microsecond Interaural Time Difference Discrimination Restored by Cochlear Implants After Neonatal Deafness". Based on this data we were able to show that neonatally deafened (ND) rats provided with precisely synchronized cochlear implant stimulation in adulthood can be trained to lateralize interaural time differences (ITDs) with essentially normal behavioral thresholds near 50 μs. Furthermore, comparable ND rats show high physiological sensitivity to ITDs immediately after binaural implantation in adulthood.
In addition to the raw data, we provided scripts to analyze the psychometric functions for the ITD sensitivity of our acoustically or electrically stimulated rats (see Fig. 1 of the manuscript). To reproduce the analysis of the electrophysiological data (see Figs. 3+4 of the manuscript), various analysis scripts were added in addition to the raw data. For a detailed description of the data analysis of these data, see section "Data analysis" of the Methods section of our manuscript.