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Reference bioassay functions for intakes of radionuclides via contaminated wounds using the ICRP OIR models

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Apr 14, 2025 version files 6.93 MB

Abstract

The NCRP wound model can be coupled with the ICRP element-specific systemic biokinetic models to describe the time-dependent retention and excretion of radioactive materials following wound contamination. A paper published in 2011 provided dose coefficients for intakes via wound, based on the dosimetric methodology from ICRP Publication 60 and the systemic biokinetic models that were current then. Since then, a new dosimetric methodology has been introduced by the ICRP in its Publication 103, and new reference phantoms have been provided in ICRP Publication 110. In addition, a series of updated systemic biokinetic models have been published by the ICRP through its Occupational intakes of Radionuclides, or OIR, series. This paper applies the latest recommendations for biokinetic and dosimetric models to derive bioassay retention functions and dose coefficients for intakes of 38 radionuclides via the wound pathway. The dose coefficients for thirty-eight radionuclides commonly encountered in nuclear weapon production, fuel fabrication or recycling, waste disposal, medicine, research, and nuclear power are calculated. These include: 3H, 14C, 32P, 35S, 59Fe, 57,58,60Co, 85,89,90Sr, 99mTc, 106Ru, 125,129,131I, 134,137Cs, 192Ir, 201Tl, 210Po, 226,228Ra, 228,230,232Th, 234,235,238U, 237Np, 238,239,240,241Pu, 241Am, 242,244Cm, and 252Cf. The dose coefficients are provided in an accompanying paper, while the reference bioassay functions (24h urine, 24h feces, whole body, skeleton and thyroid as appropriate) for these radionuclides have been presented as tables and plots here.