Data from: Phylogenomic mining of the mints reveals multiple mechanisms contributing to the evolution of chemical diversity in Lamiaceae
Data files
Jul 02, 2018 version files 2.20 GB
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Ancestral state reconstructions.zip
21.84 MB
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dryad_files_master_readme_v2.rtf
2.88 KB
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Expression abundances and functional annotataion of all 52 Lamiales species.zip
227.12 MB
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GC-MS chromatograms of 52 Lamiales species.pdf
1.65 MB
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LC-MS data of 52 Lamiales species.zip
206.97 MB
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OrthoFinder derived orthologous and paralogous groups.zip
17.87 MB
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Photographs_of_Plants_Used_in_this_Study.zip
70.92 MB
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Predicted CDS of all 52 Lamiales species.zip
477.47 MB
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Predicted peptides of all 52 Lamiales species.zip
312.99 MB
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README_for_Expression abundances and functional annotataion of all 52 Lamiales species.txt
1.11 KB
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README_for_LC-MS data of 52 Lamiales species.txt
1.84 KB
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README_for_OrthoFinder derived orthologous and paralogous groups.txt
395 B
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README_for_Photographs_of_Plants_Used_in_this_Study.rtf
1.47 KB
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Transcriptomes of all 52 Lamiales species.zip
865.01 MB
Feb 06, 2019 version files 3.48 GB
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520_genes_concatenated_alignments.zip
13.94 MB
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520_genes_MAFFT_alignments.zip
5.41 MB
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520_genes_MAFFT_edited_alignments.zip
5.44 MB
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520_genes_treefiles.zip
976.76 KB
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Ancestral state reconstructions.zip
21.84 MB
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Consortium_Members.docx
15.24 KB
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dryad_files_master_readme_v3.rtf
4.25 KB
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Expression abundances and functional annotataion of all 52 Lamiales species.zip
227.12 MB
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GC-MS chromatograms of 52 Lamiales species.pdf
1.65 MB
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LC-MS data of 52 Lamiales species.zip
206.97 MB
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OrthoFinder derived orthologous and paralogous groups.zip
17.87 MB
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Photographs_of_Plants_Used_in_this_Study.zip
70.92 MB
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Predicted CDS of all 52 Lamiales species.zip
477.47 MB
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Predicted peptides of all 52 Lamiales species.zip
312.99 MB
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README_for_Expression abundances and functional annotataion of all 52 Lamiales species.txt
1.11 KB
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README_for_LC-MS data of 52 Lamiales species.txt
1.84 KB
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README_for_OrthoFinder derived orthologous and paralogous groups.txt
395 B
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README_for_Photographs_of_Plants_Used_in_this_Study.rtf
1.47 KB
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Transcriptomes of all 52 Lamiales species.zip
865.01 MB
Abstract
The evolution of chemical complexity has been a major driver of plant diversification, with novel compounds serving as key innovations. The species-rich mint family (Lamiaceae) produces an enormous variety of compounds that act as attractants and defense molecules in nature and are used widely by humans as flavor additives, fragrances, and anti-herbivory agents. To elucidate the mechanisms by which such diversity evolved, we combined leaf transcriptome data from 48 Lamiaceae species and four outgroups with a robust phylogeny and chemical analyses of three terpenoid classes (monoterpenes, sesquiterpenes, iridoids) that share and compete for precursors. Our integrated chemical-genomic-phylogenetic approach revealed that: 1) gene family expansion rather than increased enzyme promiscuity of terpene synthases is correlated with mono- and sesqui-terpene diversity; 2) differential expression of core genes within the iridoid biosynthetic pathway is associated with iridoid presence/absence; 3) generally, production of iridoids and canonical monoterpenes appeared to be inversely correlated; and 4) iridoid biosynthesis was significantly associated with expression of geraniol synthase, which diverts metabolic flux away from canonical monoterpenes, suggesting that competition for common precursors can be a central control point in specialized metabolism. These results suggest that multiple mechanisms contributed to the evolution of chemodiversity in this economically important family.