Miłosz Wilczyński. High levels of miRNA-103/107 are associated with poor outcome in case of breast cancer patients. MiRNA-103/107- DICER axis may be one of the key regulators of cancer aggressiveness. MiRNA-103/107 expression levels have never...
Search Results
Nicholas Hum; Aimy Sebastian; Kelly Martin; Sean Gilmore; Stephen Byers; Elizabeth Wheeler; Matthew Coleman; Gabriela Loots. Cancer-associated fibroblasts (CAFs) are a prominent stromal cell type in solid tumors and molecules secreted by CAFs play an...
R. Hum Nicholas; Aimy Sebastian; F. Gilmore Sean; Wei He; A. Martin Kelly; Aubree Hinckley; R. Dubbin Karen; L. Moya Monica; K. Wheeler Elizabeth; A. Coleman Matthew; G. Loots Gabriela. Current pre-clinical models of cancer...
Maura Vrabel; David Zaharoff. Focal ablation technologies are routinely used in the clinical management of inoperable solid tumors but often result in incomplete ablations leading to high recurrence rates. Adjuvant therapies capable of safely eliminating...
5. Spatially resolved multi-omics deciphers bidirectional tumor-host interdependence in glioblastoma
Vidhya Ravi; Paulina Will; Jan Kueckelhaus; Na Sun; Kevin Joseph; Henrike Salie; Lea Vollmer; Ugne Kuliesiute; Jasmin von Ehr; Jasim K. Benotmane; Nicolas Neidert; Marie Follo; Florian Scherer; Jonathan M. Goeldner; Simon P. Behringer; Pamela...
Kenneth Hu; Matthew Krummel; Kelly Kersten. T cell exhaustion is a major impediment to antitumor immunity. However, it remains elusive how other immune cells in the tumor microenvironment (TME) contribute to this dysfunctional state. Here,...
Nazmul Islam; Alok Atreya; Samata Nepal; Jashim Uddin Kazi; Rashed Kaiser Md.; G Menezes Ritesh; Savita Lasrado; Muhammad Abdullah-Al-Noman. Background: A cancer patient's quality of life (QoL) is the perception of their physical, functional, psychological, and...
Narendra Padhan; E.M. Nordling Torbjörn; Magnus Sundström; Peter Åkerud; Helgi Birgisson; Peter Nygren; Sven Nelander; Lena Claesson-Welsh. Background: The progression of colorectal cancer (CRC) involves recurrent amplifications/mutations in the epidermal growth factor receptor (EGFR) and...
9. Single-cell expression and TCR data from CD19-specific CAR T cells in a phase I/II clinical trial
Hyunjin Kim; G. Thomas Paul; Chase Crawford Jeremy. By leveraging single-cell transcriptome and T cell receptor (TCR) sequencing, we aimed to track the transcriptional signatures of CAR T cell clonotypes throughout the course of treatment...
Jing Shi; Tao Jiao; Qian Guo; Weining Weng; Linjie Ma; Qing Zhang; Lijun Wang; Jianjian Zhang; Caiwei Chen; Yaling Huang; Mingqiao Wang; Rong Pan; Yanfang Tang; Wenhao Hu; Tao Meng; Shu-Hui Liu; Jun Guo; Yan...