Show simple item record Morimoto, Juliano Senior, Alistair M Ruiz, Kate Wali, Jibran Pulpitel, Tamara Solon-Biet, Samantha M. Cogger, Victoria Raubenheimer, David Le Couteur, David G Simpson, Stephen J. Eberhard, Joerg 2019-03-14T20:55:26Z 2019-03-14T20:55:26Z 2019-03-13
dc.identifier doi:10.5061/dryad.7c702sb
dc.identifier.citation Morimoto J, Senior A, Ruiz K, Wali JA, Pulpitel T, Solon-Biet SM, Cogger VC, Raubenheimer D, Le Couteur DG, Simpson SJ, Eberhard J (2019) Sucrose and starch intake contribute to reduced alveolar bone height in a rodent model of naturally occurring periodontitis. PLOS ONE 14(3): e0212796.
dc.description While there is a burgeoning interest in the effects of nutrition on systemic inflammatory diseases, how dietary macronutrient balance impacts local chronic inflammatory diseases in the mouth has been largely overlooked. Here, we used the Geometric Framework for Nutrition to test how the amounts of dietary macronutrients and their interactions, as well as carbohydrate type (starch vs sucrose vs resistant starch) influenced periodontitis-associated alveolar bone height in mice. Increasing intake of carbohydrates reduced alveolar bone height, while dietary protein had no effect. Whether carbohydrate came from sugar or starch did not influence the extent of alveolar bone height. In summary, the amount of carbohydrate in the diet modulated periodontitis-associated alveolar bone height independent of the source of carbohydrates.
dc.relation.haspart doi:10.5061/dryad.7c702sb/1
dc.relation.isreferencedby doi:10.1371/journal.pone.0212796
dc.subject Animal model
dc.subject periodontitis
dc.subject carbohydrate
dc.subject geometric framework for nutrition
dc.subject diet
dc.title Data from: Sucrose and starch intake contribute to reduced alveolar bone height in a rodent model of naturally occurring periodontitis
dc.type Article
dwc.ScientificName Mus musculus
dc.contributor.correspondingAuthor Senior, Alistair M.
prism.publicationName PLOS ONE
dryad.dansTransferDate 2019-05-03T07:37:47.116+0000
dryad.dansArchiveDate 2019-05-03T09:01:43.035+0000

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