The aim of this dataset was to compare the effects of single nerve transfer and double nerve transfer on muscle mass. We developed a novel rat model to investigate the neurophysiological effects of peripheral double nerve transfers to a single target muscle. In 62 male Sprague-Dawley rats the ulnar nerve of the antebrachium alone (n=30) or together with the anterior interosseus nerve (n=32) was transferred to reinnervate the long head of the biceps brachii. To further assess reinnervation, muscle mass was analyzed. Twelve weeks following surgery, after successful reinnervation was confirmed by muscle response to nerve crush and neurotomy, the long head of the biceps muscles were harvested and weighed. To provide internal control, the untreated contralateral muscle heads were also harvested and weighed.

The entire long head of the biceps was removed and weighed using a precision scale.