Effects of phloretin, ritonavir, indinavir and Bay-876 on glucose transport during peritoneal dialysis in Sprague-Dawley rats
Data files
Aug 07, 2024 version files 148.89 KB
Abstract
We previously found that phloretin, a general blocker of facilitative glucose channels (GLUTs), reduced glucose absorption and improved ultrafiltration during peritoneal dialysis (PD) in rats. It is as yet unknown via which GLUTs such transport occurs and whether transport occurs in a trans-cellular fashion. This study was undertaken to elucidate (i) whether glucose may be transferred in a trans-cellular fashion across peritoneal cells and (ii) via which GLUTs glucose transport may be partly mediated during PD. The main study was performed in thirty-two Sprague-Dawley rats in which PD was performed by instillation of 20 mL 2.3% glucose PD fluid which was allowed to dwell for 60 min. Animals were given an IV infusion of [18F]-deoxyglucose allowing us to monitor glucose transport in both directions: from the dialysate to the circulation and vice versa. Animals received either no treatment (control), or received intra-peritoneal phloretin (50 mg/L), ritonavir (60 mg/L), or BAY-876 (25 mg/L). Water and transfer of low-molecular solutes were closely monitored during dialysis. Additional experiments were then performed in sixteen rats using receiving either no treatment (control) or intra-peritoneal indinavir (50 mg/L).
README
GENERAL INFORMATION
- Title of Dataset: Effects of Phloretin, Ritonavir, Indinavir, and BAY-876 on Glucose Transport During Peritoneal Dialysis in Sprague-Dawley Rats
- Author Information A. Principal Investigator Contact Information Name: Carl Öberg Institution: Lund University, Medical Faculty Address: Box 117, SE-221 00 Email: carl.oberg@med.lu.se
- Date of data collection June 2022 to September 2023
- Geographic location of data collection: Lund, Sweden
- Information about funding sources that supported the collection of the data: Funding by the Crafoord Foundation, Lund University Medical Faculty Foundation grant YF 2020-YF0056, and The Inga-Britt and Arne Lundberg’s Research Foundation (all to C.M. Öberg).
DATA & FILE OVERVIEW
- File List: fdgdata.xls, indinavir.xls
DATA-SPECIFIC INFORMATION FOR: fdgdata.xls
- Number of variables: 130
- Number of cases/rows: 32
- Variable List:
animal, "unique number assigned to each animal"
treatment, "Dialysis fluid used, e.g. LowNa 1.5% represents low sodium and 1.5% glucose strength"
weight, "Body weight in grams before dialysis"
date, "Date of the experiment YYYY-MM-DD"
vin, "Peritoneal dialysis fluid volume instilled in milliliters"
vout, "Peritoneal dialysis fluid volume extracted in milliliters (see manuscript for details)"
uvol, "Total urine volume"
ufdgcpm,"18-F activity in urine sample Bq/mL"
p_na_before, "Plasma sodium concentration before dialysis in mmol/L"
p_k_before, "Plasma potassium concentration before dialysis in mmol/L"
p_cl_before, "Plasma chloride concentration before dialysis in mmol/L"
p_ica_before, "Plasma ionized calcium concentration before dialysis in mmol/L"
p_tco2_before, "Plasma total carbon dioxide concentration before dialysis in mmol/L"
p_glu_before, "Plasma glucose concentration before dialysis in mmol/L"
p_urea_before, "Plasma urea concentration before dialysis in mmol/L"
p_crea_before, "Plasma creatinine concentration before dialysis in mmol/L"
map_before, "Mean arterial pressure before dialysis in mmol/L"
hr_before, "Heart rate before dialysis in mmol/L"
p_na_after, "Plasma sodium concentration after dialysis in mmol/L"
p_k_after, "Plasma potassium concentration after dialysis in mmol/L"
p_cl_after, "Plasma chloride concentration after dialysis in mmol/L"
p_ica_after, "Plasma ionized calcium concentration after dialysis in mmol/L"
p_tco2_after, "Plasma total carbon dioxide concentration before dialysis in mmol/L"
p_glu_after, "Plasma glucose concentration after dialysis in mmol/L"
p_urea_after, "Plasma urea concentration after dialysis in mmol/L"
p_crea_after, "Plasma creatinine concentration after dialysis in mmol/L"
map_after, "Mean arterial pressure before dialysis in mmol/L"
hr_after, "Heart rate before dialysis in mmol/L"
n_p_samples, "Number of blood samples obtained during dialysis"
pt1, "Time point for blood sample #1 in minutes post start of dialysis"
pt2, "Time point for blood sample #2 in minutes post start of dialysis"
pt3, "Time point for blood sample #3 in minutes post start of dialysis"
pt4, "Time point for blood sample #4 in minutes post start of dialysis"
pt5, "Time point for blood sample #5 in minutes post start of dialysis"
pt6, "Time point for blood sample #6 in minutes post start of dialysis"
hb_before, "Blood hemoglobin concentration before dialysis in g/L"
hb_after, "Blood hemoglobin concentration after dialysis in g/L"
hct_before, "Blood hematocrit before dialysis"
hct_after, "Blood hematocrit after dialysis"
p_fdg_1, "Plasma 18F activity (blood sample #1) in Bq/mL"
p_fdg_2, "Plasma 18F activity (blood sample #2) in Bq/mL"
p_fdg_3, "Plasma 18F activity (blood sample #3) in Bq/mL"
p_fdg_4, "Plasma 18F activity (blood sample #4) in Bq/mL"
p_fdg_5, "Plasma 18F activity (blood sample #5) in Bq/mL"
p_fdg_6, "Plasma 18F activity (blood sample #6) in Bq/mL"
n_d_samples, "Number of dialysate samples obtained during dialysis"
d_sv_1, "Sampling volume for dialysate sample #1 in milliliters"
d_sv_2, "Sampling volume for dialysate sample #2 in milliliters"
d_sv_3, "Sampling volume for dialysate sample #3 in milliliters"
d_sv_4, "Sampling volume for dialysate sample #4 in milliliters"
d_sv_5, "Sampling volume for dialysate sample #5 in milliliters"
d_sv_6, "Sampling volume for dialysate sample #6 in milliliters"
d_sv_7, "Sampling volume for dialysate sample #7 in milliliters"
d_fdg_1, "18F activity in dialysate sample #1 in Bq/mL"
d_fdg_2, "18F activity in dialysate sample #2 in Bq/mL"
d_fdg_3, "18F activity in dialysate sample #3 in Bq/mL"
d_fdg_4, "18F activity in dialysate sample #4 in Bq/mL"
d_fdg_5, "18F activity in dialysate sample #5 in Bq/mL"
d_fdg_6, "18F activity in dialysate sample #6 in Bq/mL"
d_fdg_7, "18F activity in dialysate sample #7 in Bq/mL"
d_glu_0, "Measured glucose concentration in fresh dialysis fluid (before instillation) in mmol/L"
d_glu_1, "Measured glucose concentration in dialysate sample #1 in mmol/L"
d_glu_2, "Measured glucose concentration in dialysate sample #2 in mmol/L"
d_glu_3, "Measured glucose concentration in dialysate sample #3 in mmol/L"
d_glu_4, "Measured glucose concentration in dialysate sample #4 in mmol/L"
d_glu_5, "Measured glucose concentration in dialysate sample #5 in mmol/L"
d_glu_6, "Measured glucose concentration in dialysate sample #6 in mmol/L"
d_glu_7, "Measured glucose concentration in dialysate sample #7 in mmol/L"
d_na_0, "Measured sodium concentration in fresh dialysis fluid (before instillation) in mmol/L"
d_na_1, "Measured glucose concentration in dialysate sample #1 in mmol/L"
d_na_2, "Measured glucose concentration in dialysate sample #2 in mmol/L"
d_na_3, "Measured glucose concentration in dialysate sample #3 in mmol/L"
d_na_4, "Measured glucose concentration in dialysate sample #4 in mmol/L"
d_na_5, "Measured glucose concentration in dialysate sample #5 in mmol/L"
d_na_6, "Measured glucose concentration in dialysate sample #6 in mmol/L"
d_na_7, "Measured glucose concentration in dialysate sample #7 in mmol/L"
d_k_0, "Measured potassium concentration in fresh dialysis fluid (before instillation) in mmol/L"
d_k_1, "Measured potassium concentration in dialysate sample #1 in mmol/L"
d_k_2, "Measured potassium concentration in dialysate sample #2 in mmol/L"
d_k_3, "Measured potassium concentration in dialysate sample #3 in mmol/L"
d_k_4, "Measured potassium concentration in dialysate sample #4 in mmol/L"
d_k_5, "Measured potassium concentration in dialysate sample #5 in mmol/L"
d_k_6, "Measured potassium concentration in dialysate sample #6 in mmol/L"
d_k_7, "Measured potassium concentration in dialysate sample #7 in mmol/L"
d_cl_0, "Measured chloride concentration in fresh dialysis fluid (before instillation) in mmol/L"
d_cl_1, "Measured chloride concentration in dialysate sample #1 in mmol/L"
d_cl_2, "Measured chloride concentration in dialysate sample #2 in mmol/L"
d_cl_3, "Measured chloride concentration in dialysate sample #3 in mmol/L"
d_cl_4, "Measured chloride concentration in dialysate sample #4 in mmol/L"
d_cl_5, "Measured chloride concentration in dialysate sample #5 in mmol/L"
d_cl_6, "Measured chloride concentration in dialysate sample #6 in mmol/L"
d_cl_7, "Measured chloride concentration in dialysate sample #7 in mmol/L"
d_ica_0, "Measured ionized calcium concentration in fresh dialysis fluid (before instillation) in mmol/L"
d_ica_1, "Measured ionized calcium concentration in dialysate sample #1 in mmol/L"
d_ica_2, "Measured ionized calcium concentration in dialysate sample #2 in mmol/L"
d_ica_3, "Measured ionized calcium concentration in dialysate sample #3 in mmol/L"
d_ica_4, "Measured ionized calcium concentration in dialysate sample #4 in mmol/L"
d_ica_5, "Measured ionized calcium concentration in dialysate sample #5 in mmol/L"
d_ica_6, "Measured ionized calcium concentration in dialysate sample #6 in mmol/L"
d_ica_7, "Measured ionized calcium concentration in dialysate sample #7 in mmol/L"
d_tco2_0, "Measured total carbon dioxide concentration in fresh dialysis fluid (before instillation) in mmol/L"
d_tco2_1, "Measured total carbon dioxide concentration in dialysate sample #1 in mmol/L"
d_tco2_2, "Measured total carbon dioxide concentration in dialysate sample #1 in mmol/L"
d_tco2_3, "Measured total carbon dioxide concentration in dialysate sample #1 in mmol/L"
d_tco2_4, "Measured total carbon dioxide concentration in dialysate sample #1 in mmol/L"
d_tco2_5, "Measured total carbon dioxide concentration in dialysate sample #1 in mmol/L"
d_tco2_6, "Measured total carbon dioxide concentration in dialysate sample #1 in mmol/L"
d_tco2_7, "Measured total carbon dioxide concentration in dialysate sample #1 in mmol/L"
d_urea_1, "Measured urea concentration in dialysate sample #1 in mmol/L"
d_urea_2, "Measured urea concentration in dialysate sample #2 in mmol/L"
d_urea_3, "Measured urea concentration in dialysate sample #3 in mmol/L"
d_urea_4, "Measured urea concentration in dialysate sample #4 in mmol/L"
d_urea_5, "Measured urea concentration in dialysate sample #5 in mmol/L"
d_urea_6, "Measured urea concentration in dialysate sample #6 in mmol/L"
d_urea_7, "Measured urea concentration in dialysate sample #7 in mmol/L"
d_crea_0, "Measured creatinine concentration in fresh dialysis fluid (before instillation) in μmol/L"
d_crea_1, "Measured creatinine concentration in dialysate sample #1 in μmol/L"
d_crea_2, "Measured creatinine concentration in dialysate sample #2 in μmol/L"
d_crea_3, "Measured creatinine concentration in dialysate sample #3 in μmol/L"
d_crea_4, "Measured creatinine concentration in dialysate sample #4 in μmol/L"
d_crea_5, "Measured creatinine concentration in dialysate sample #5 in μmol/L"
d_crea_6, "Measured creatinine concentration in dialysate sample #6 in μmol/L"
d_crea_7, "Measured creatinine concentration in dialysate sample #7 in μmol/L"
dt1, "Time point for dialysate sample #1 in minutes post start of dialysis"
dt2, "Time point for dialysate sample #2 in minutes post start of dialysis"
dt3, "Time point for dialysate sample #3 in minutes post start of dialysis"
dt4, "Time point for dialysate sample #4 in minutes post start of dialysis"
dt5, "Time point for dialysate sample #5 in minutes post start of dialysis"
dt6, "Time point for dialysate sample #6 in minutes post start of dialysis"
dt7, "Time point for dialysate sample #7 in minutes post start of dialysis"
- Missing data codes: NA
DATA-SPECIFIC INFORMATION FOR: indinavir.xls
- Number of variables: 155
- Number of cases/rows: 16
- Variable List:
animal, "unique number assigned to each animal"
treatment, "Control (no treatment) or indinavir"
weight_before, "Body weight in grams before dialysis"
weight_after, "Body weight in grams after dialysis"
date, "Date of the experiment YYYY-MM-DD"
vin, "Peritoneal dialysis fluid volume instilled in milliliters"
vout, "Peritoneal dialysis fluid volume extracted in milliliters (see manuscript for details)"
wo_in, "Wash-out fluid volume instilled (typically 15 mL)"
wo_out, "Wash-out fluid volume drained (see manuscript for details)"
wo_alb, "125I activity in wash-out fluid in Bq/mL"
uvol, "Total urine volume in mL"
u_glu, "Urine glucose concentration in mmol/L"
uristix, "Urine glucose concentration as indicated by a dipstick test (Uristix)"
u_alb, "125I activity in urine in Bq/mL"
u_edta, "51Cr activity in urine in Bq/mL"
p_na_before, "Plasma sodium concentration before dialysis in mmol/L"
p_k_before, "Plasma potassium concentration before dialysis in mmol/L"
p_cl_before, "Plasma chloride concentration before dialysis in mmol/L"
p_ica_before, "Plasma ionized calcium concentration before dialysis in mmol/L"
p_tco2_before, "Plasma total carbon dioxide concentration before dialysis in mmol/L"
p_glu_before, "Plasma glucose concentration before dialysis in mmol/L"
p_urea_before, "Plasma urea concentration before dialysis in mmol/L"
p_crea_before, "Plasma creatinine concentration before dialysis in mmol/L"
map_before, "Mean arterial pressure before dialysis in mmol/L"
hr_before, "Heart rate before dialysis in mmol/L"
p_na_after, "Plasma sodium concentration after dialysis in mmol/L"
p_k_after, "Plasma potassium concentration after dialysis in mmol/L"
p_cl_after, "Plasma chloride concentration after dialysis in mmol/L"
p_ica_after, "Plasma ionized calcium concentration after dialysis in mmol/L"
p_tco2_after, "Plasma total carbon dioxide concentration before dialysis in mmol/L"
p_glu_after, "Plasma glucose concentration after dialysis in mmol/L"
p_urea_after, "Plasma urea concentration after dialysis in mmol/L"
p_crea_after, "Plasma creatinine concentration after dialysis in mmol/L"
map_after, "Mean arterial pressure before dialysis in mmol/L"
hr_after, "Heart rate before dialysis in mmol/L"
n_p_samples, "Number of blood samples obtained during dialysis"
pt1, "Time point for blood sample #1 in minutes post start of dialysis"
pt2, "Time point for blood sample #2 in minutes post start of dialysis"
pt3, "Time point for blood sample #3 in minutes post start of dialysis"
pt4, "Time point for blood sample #4 in minutes post start of dialysis"
pt5, "Time point for blood sample #5 in minutes post start of dialysis"
pt6, "Time point for blood sample #6 in minutes post start of dialysis"
hb_before, "Blood hemoglobin concentration before dialysis in g/L"
hb_after, "Blood hemoglobin concentration after dialysis in g/L"
p_hct_1, "Blood hematocrit for blood sample #1 in minutes post start of dialysis"
p_hct_2, "Blood hematocrit for blood sample #2 in minutes post start of dialysis"
p_hct_3, "Blood hematocrit for blood sample #3 in minutes post start of dialysis"
p_hct_4, "Blood hematocrit for blood sample #4 in minutes post start of dialysis"
p_hct_5, "Blood hematocrit for blood sample #5 in minutes post start of dialysis"
p_hct_6, "Blood hematocrit for blood sample #6 in minutes post start of dialysis"
p_edta_1, "Plasma 51Cr activity (blood sample #1) in Bq/mL"
p_edta_2, "Plasma 51Cr activity (blood sample #2) in Bq/mL"
p_edta_3, "Plasma 51Cr activity (blood sample #3) in Bq/mL"
p_edta_4, "Plasma 51Cr activity (blood sample #4) in Bq/mL"
p_edta_5, "Plasma 51Cr activity (blood sample #5) in Bq/mL"
p_edta_6, "Plasma 51Cr activity (blood sample #6) in Bq/mL"
p_alb_1, "Plasma 125I activity (blood sample #1) in Bq/mL"
p_alb_2, "Plasma 125I activity (blood sample #2) in Bq/mL"
p_alb_3, "Plasma 125I activity (blood sample #3) in Bq/mL"
p_alb_4, "Plasma 125I activity (blood sample #4) in Bq/mL"
p_alb_5, "Plasma 125I activity (blood sample #5) in Bq/mL"
p_alb_6, "Plasma 125I activity (blood sample #6) in Bq/mL"
n_d_samples, "Number of dialysate samples obtained during dialysis"
d_sv_1, "Sampling volume for dialysate sample #1 in milliliters"
d_sv_2, "Sampling volume for dialysate sample #2 in milliliters"
d_sv_3, "Sampling volume for dialysate sample #3 in milliliters"
d_sv_4, "Sampling volume for dialysate sample #4 in milliliters"
d_sv_5, "Sampling volume for dialysate sample #5 in milliliters"
d_sv_6, "Sampling volume for dialysate sample #6 in milliliters"
d_sv_7, "Sampling volume for dialysate sample #7 in milliliters"
d_edta_0, "51Cr activity in dialysis fluid (before instillation) in Bq/mL"
d_edta_1, "51Cr activity in dialysate sample #1 in Bq/mL"
d_edta_2, "51Cr activity in dialysate sample #2 in Bq/mL"
d_edta_3, "51Cr activity in dialysate sample #3 in Bq/mL"
d_edta_4, "51Cr activity in dialysate sample #4 in Bq/mL"
d_edta_5, "51Cr activity in dialysate sample #5 in Bq/mL"
d_edta_6, "51Cr activity in dialysate sample #6 in Bq/mL"
d_edta_7, "51Cr activity in dialysate sample #7 in Bq/mL"
d_alb_0, "125I activity in dialysis fluid (before instillation) in Bq/mL"
d_alb_1, "125I activity in dialysate sample #1 in Bq/mL"
d_alb_2, "125I activity in dialysate sample #2 in Bq/mL"
d_alb_3, "125I activity in dialysate sample #3 in Bq/mL"
d_alb_4, "125I activity in dialysate sample #4 in Bq/mL"
d_alb_5, "125I activity in dialysate sample #5 in Bq/mL"
d_alb_6, "125I activity in dialysate sample #6 in Bq/mL"
d_alb_7, "125I activity in dialysate sample #7 in Bq/mL"
d_glu_1, "Measured glucose concentration in dialysate sample #1 in mmol/L"
d_glu_2, "Measured glucose concentration in dialysate sample #2 in mmol/L"
d_glu_3, "Measured glucose concentration in dialysate sample #3 in mmol/L"
d_glu_4, "Measured glucose concentration in dialysate sample #4 in mmol/L"
d_glu_5, "Measured glucose concentration in dialysate sample #5 in mmol/L"
d_glu_6, "Measured glucose concentration in dialysate sample #6 in mmol/L"
d_glu_7, "Measured glucose concentration in dialysate sample #7 in mmol/L"
d_na_0, "Sodium concentration in fresh dialysis fluid (before instillation) in mmol/L"
d_na_1, "Measured glucose concentration in dialysate sample #1 in mmol/L"
d_na_2, "Measured glucose concentration in dialysate sample #2 in mmol/L"
d_na_3, "Measured glucose concentration in dialysate sample #3 in mmol/L"
d_na_4, "Measured glucose concentration in dialysate sample #4 in mmol/L"
d_na_5, "Measured glucose concentration in dialysate sample #5 in mmol/L"
d_na_6, "Measured glucose concentration in dialysate sample #6 in mmol/L"
d_na_7, "Measured glucose concentration in dialysate sample #7 in mmol/L"
d_k_0, "Potassium concentration in fresh dialysis fluid (before instillation) in mmol/L"
d_k_1, "Measured potassium concentration in dialysate sample #1 in mmol/L"
d_k_2, "Measured potassium concentration in dialysate sample #2 in mmol/L"
d_k_3, "Measured potassium concentration in dialysate sample #3 in mmol/L"
d_k_4, "Measured potassium concentration in dialysate sample #4 in mmol/L"
d_k_5, "Measured potassium concentration in dialysate sample #5 in mmol/L"
d_k_6, "Measured potassium concentration in dialysate sample #6 in mmol/L"
d_k_7, "Measured potassium concentration in dialysate sample #7 in mmol/L"
d_cl_0, "Chloride concentration in fresh dialysis fluid (before instillation) in mmol/L"
d_cl_1, "Measured chloride concentration in dialysate sample #1 in mmol/L"
d_cl_2, "Measured chloride concentration in dialysate sample #2 in mmol/L"
d_cl_3, "Measured chloride concentration in dialysate sample #3 in mmol/L"
d_cl_4, "Measured chloride concentration in dialysate sample #4 in mmol/L"
d_cl_5, "Measured chloride concentration in dialysate sample #5 in mmol/L"
d_cl_6, "Measured chloride concentration in dialysate sample #6 in mmol/L"
d_cl_7, "Measured chloride concentration in dialysate sample #7 in mmol/L"
d_ica_1, "Measured ionized calcium concentration in dialysate sample #1 in mmol/L"
d_ica_2, "Measured ionized calcium concentration in dialysate sample #2 in mmol/L"
d_ica_3, "Measured ionized calcium concentration in dialysate sample #3 in mmol/L"
d_ica_4, "Measured ionized calcium concentration in dialysate sample #4 in mmol/L"
d_ica_5, "Measured ionized calcium concentration in dialysate sample #5 in mmol/L"
d_ica_6, "Measured ionized calcium concentration in dialysate sample #6 in mmol/L"
d_ica_7, "Measured ionized calcium concentration in dialysate sample #7 in mmol/L"
d_tco2_0, "Total carbon dioxide concentration in fresh dialysis fluid (before instillation) in mmol/L"
d_tco2_1, "Measured total carbon dioxide concentration in dialysate sample #1 in mmol/L"
d_tco2_2, "Measured total carbon dioxide concentration in dialysate sample #1 in mmol/L"
d_tco2_3, "Measured total carbon dioxide concentration in dialysate sample #1 in mmol/L"
d_tco2_4, "Measured total carbon dioxide concentration in dialysate sample #1 in mmol/L"
d_tco2_5, "Measured total carbon dioxide concentration in dialysate sample #1 in mmol/L"
d_tco2_6, "Measured total carbon dioxide concentration in dialysate sample #1 in mmol/L"
d_tco2_7, "Measured total carbon dioxide concentration in dialysate sample #1 in mmol/L"
d_urea_1, "Measured urea concentration in dialysate sample #1 in mmol/L"
d_urea_2, "Measured urea concentration in dialysate sample #2 in mmol/L"
d_urea_3, "Measured urea concentration in dialysate sample #3 in mmol/L"
d_urea_4, "Measured urea concentration in dialysate sample #4 in mmol/L"
d_urea_5, "Measured urea concentration in dialysate sample #5 in mmol/L"
d_urea_6, "Measured urea concentration in dialysate sample #6 in mmol/L"
d_urea_7, "Measured urea concentration in dialysate sample #7 in mmol/L"
d_crea_1, "Measured creatinine concentration in dialysate sample #1 in μmol/L"
d_crea_2, "Measured creatinine concentration in dialysate sample #2 in μmol/L"
d_crea_3, "Measured creatinine concentration in dialysate sample #3 in μmol/L"
d_crea_4, "Measured creatinine concentration in dialysate sample #4 in μmol/L"
d_crea_5, "Measured creatinine concentration in dialysate sample #5 in μmol/L"
d_crea_6, "Measured creatinine concentration in dialysate sample #6 in μmol/L"
d_crea_7, "Measured creatinine concentration in dialysate sample #7 in μmol/L"
dt1, "Time point for dialysate sample #1 in minutes post start of dialysis"
dt2, "Time point for dialysate sample #2 in minutes post start of dialysis"
dt3, "Time point for dialysate sample #3 in minutes post start of dialysis"
dt4, "Time point for dialysate sample #4 in minutes post start of dialysis"
dt5, "Time point for dialysate sample #5 in minutes post start of dialysis"
dt6, "Time point for dialysate sample #6 in minutes post start of dialysis"
dt7, "Time point for dialysate sample #7 in minutes post start of dialysis"
- Missing data codes: NA