README: Wired together, change together: Spike timing modifies transmission in converging assemblies

https://doi.org/10.5061/dryad.j9kd51ck2

This dataset encompasses extracellular recordings obtained from freely moving mice, integral to the research presented in our manuscript titled "Wired together, change together: Spike timing modifies transmission in converging assemblies." The data primarily consist of neuronal spike timing, LFP, optogenetic stimulation, and other useful information for working with the dataset.

Description of the data and file structure

The dataset is organized by session, with each folder containing data from a single session. Folders ending with a number (e.g., mP79_20) encompass data from the closed-loop experiment sessions. In contrast, folders ending with 'Control' contain data from control sessions, where no stimulation was administered during the defined 'Before' and 'After' periods.

Within each folder, data are further categorized into subfolders named according to the specific session. Each session folder houses a comprehensive set of files that includes:

1. '.res' Files: These files record spike timings in samples per shank. For instance, the file 'mP31_22.res.1' contains spike timing data from the first shank recorded in session 'mP31_22'.
2. '.clu' Files: Corresponding to the '.res' files, these files label the spike units. The first element in a '.clu' file denotes the total number of recorded units.
3. '.eeg' Files: These files contain the extracellular data sampled at 1250 Hz, incorporating both neuronal and auxiliary channels such as those used for light stimulation.
4. '.xml' Files: Each '.xml' file provides meta-information necessary for interpreting the '.eeg' file. This includes details on number of channels, sampling rates, and other technical specifications.
5. '.prm.xml' Files: These contain metadata specific to each recorded channel.

In addition to these files, the data includes '.xls' files, which details the times (in minutes) for each epoch used in the analysis, and the pairs of units which used in the analisys.

This structured organization and detailed file description aim to facilitate ease of access and comprehension for potential data users, regardless of their familiarity with the specific methodologies or terminologies used in this field.