Data from: Efficacy of negative feedback in the HPA axis predicts recovery from acute challenges.
Taff, Conor C., Cornell University
Zimmer, Cedric, Cornell University
Vitousek, Maren N., Cornell University
Published Jun 25, 2018 on Dryad.
Cite this dataset
Taff, Conor C.; Zimmer, Cedric; Vitousek, Maren N. (2018). Data from: Efficacy of negative feedback in the HPA axis predicts recovery from acute challenges. [Dataset]. Dryad. https://doi.org/10.5061/dryad.v00q39g
The glucocorticoid stress response mediates a suite of physiological and behavioral changes that allow vertebrates to cope with transient stressors. Chronically elevated glucocorticoid levels are known to result in a variety of organismal costs, but relatively little is known about the downstream effects of mounting a series of brief, acute spikes in circulating glucocorticoids. Conceptual models of stress suggest that repeated acute stressors might produce ‘wear-and-tear’ on the stress response system when encountered in sequence. We used a novel technique to experimentally induce acute corticosterone spikes on either three or six consecutive days in incubating tree swallows. Consistent with the ‘wear-and-tear’ hypothesis, we found that i) a sequence of corticosterone spikes produced cumulative effects on corticosterone regulation, ii) treatment frequency predicted the severity of consequences, and iii) individual variation in the ability to terminate the stress response through negative feedback predicted the duration of physiological disruption in the group that experienced the most frequent challenges. Our results illustrate the importance of assessing multiple aspects of the hormonal stress response and have implications for understanding both individual and population resilience to repeated transient stressors.
Main data file
Data used in analyses presented in the paper.
R analysis code
Code to reproduce analyses and figures included in the paper. Also includes descriptions of columns included in the data file.
Code and description of data used to produce all analyses presented in the paper.