Subjective sleep quality and sleep architecture in patients with migraine: a meta-analysis
Data files
Aug 18, 2021 version files 55.27 KB
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DATA-README.txt
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data.zip
53.45 KB
Abstract
Sleep disturbance is often associated with migraine. However, there is a paucity of research investigating objective and subjective measures of sleep in migraine patients. This meta-analysis aims to determine whether there are differences in subjective sleep quality measured using the Pittsburgh Sleep Quality Index (PSQI), and objective sleep physiology measured using polysomnography between adult and pediatric patients, and healthy controls. This review was pre-registered on PROSPERO (CRD42020209325). A systematic search of five databases (Embase, MEDLINE®, Global Health, APA PsycINFO, APA PsycArticles, last searched: 12/17/2020) was conducted to find case-controlled studies that measured polysomnography and/or PSQI in patients with migraine. Pregnant participants and those with other headache disorders were excluded. Effect sizes (Hedges’ g) were entered into a random effects model meta-analysis. Study quality was evaluated with the Newcastle Ottawa Scale and publication bias with Egger’s regression test. 32 studies were eligible, of which 21 measured PSQI and/or MIDAS in adults, 6 measured PSG in adults, and 5 in children. The overall mean study quality score was 5/9, and this did not moderate any of the results, and there was no risk of publication bias. Overall, adults with migraine had higher PSQI scores than healthy controls (g=0.75, p < .001, 95% confidence interval [95% CI]: 0.54 - 0.96). This effect was larger in those with chronic rather than episodic conditions (g=1.03, p < .001, 95% CI: 0.37 - 1.01, g = 0.63, p < .001, 95% CI: 0.38 - 0.88 respectively). For polysomnographic studies, adults and children with migraine displayed a lower percentage of REM sleep (g=-0.22, p = 0.017, 95% CI: -0.41 - -0.04, g = -0.71, p = 0.025, 95% CI: -1.34 - -0.10 respectively) than controls. Pediatric patients displayed less total sleep time (g=-1.37, p = 0.039, 95% CI: -2.66 - -0.10), more wake (g=0.52, p < .001, 95% CI: 0.08 – 0.79) and shorter sleep onset latency (g=-0.37, p < .001, 95% CI: -0.54 - -0.21) than controls. People with migraines have significantly poorer subjective sleep quality and altered sleep physiology compared to healthy individuals. Further longitudinal empirical studies are required to enhance our understanding of this relationship.
README: Subjective sleep quality and sleep architecture in patients with migraine: a meta-analysis
https://doi.org/10.5061/dryad.vq83bk3sf
There is an additional README file within the RStudio software project that explains how to run the necessary analysis scripts.
Data are stored in .csv format.
Each file contains a different sleep measure (PSQI, PSG, MIDAS & PSQI) for migraine patients and controls.
In each file, there are the following columns:
- 1) Authors_year - detailing the authors and year of the published journal article.
- 2) Country of publication - the country the article was published in.
- 3) Publication Type - what type of publication it is
- 4) Year - the year the article was published
- 5) Journal - the peer-reviewed journal that the article was published in
- 6) M_n = this indicates the sample size (n) for that respective parameter for the migraine group (M)
- 7) M_M = this indicates the mean of the migraine group (M) for that particular sleep parameter
- 8) M_sd = this indicates the standard deviation for the migraine group for that particular sleep parameter
- 9) C_n = this indicates the sample size (n) for that respective parameter for the control group (C)
- 10) C_M = this indicates the mean of the control group (C) for that particular sleep parameter
- 11) C_sd = this indicates the standard deviation for the healthy control group (C) for that particular sleep parameter
- 12) migraine_frequency = this indicates the frequency of migraine which that article studies/includes
- 13) drug_control = this indicates whether the study in question excluded patients on medication/drugs which would affect the sleep cycle or not
- 14) sleep_disorders = this indicates whether or not the study in question excluded participants with sleep disorders
- 15) matched_controls = this indicates whether or not the study in question matched their control population to their migraine population based on sex and age
- 16) ROB_score = this indicates the risk of bias score or study quality score out of 6 for each study which is based on the Newcastle Ottawa Scale.
Methods
This dataset includes the means and standard deviations from adult and paediatric migraine patients and healthy controls for global Pittsburgh Sleep Quality Index scores, and polysomnography parameters (REM, N1, N2, N3, wake percentages, total sleep time, and sleep onset latency in minutes) as well as the n for each group taken directly from published journal articles. The dataset also includes other information such as the original article's authors, title of the article, country of publication, abstract, year published, journal published in, the measures of sleep that the study collected, risk of bias/study quality assessment scores, and other information that could be potential moderating variables.