GENERAL INFORMATION 1. Title of Dataset: Data for Radial arm maze tests and Novel object recognition tests 2. Author Information: Corresponding Investigator Name: Dr Kiranmai S Rai Institution: Department of Physiology, Manipal Academy of Higher Education, Manipal, India Email: hod.physio@gmail.com Co-investigator 1 Name: Mr Shreevatsa Bhat M Institution: Department of Physiology, Manipal Academy of Higher Education, Manipal, India Co-investigator 2 Name: Dr Ramesh Babu M G Institution: Department of Physiology, Manipal Academy of Higher Education, Manipal, India Co-investigator 3 Name: Dr Anandh D Institution: Department of Regenerative Medicine, MIRM, Manipal Academy of Higher Education, Bengaluru, India 3. Date of data collection: 2018-2020 4. Geographic location of data collection: Manipal,Karnataka,India DATA & FILE OVERVIEW 1. Description of dataset These data were generated to explore the comparative benefits of potential memory-enhancing strategies like supplementation of choline and docosahexaenoic acid (DHA) or administration of conditioned media derived from human embryonic kidney stem cells (HEK-CM) or exposure to environmental enrichment (EE), that attenuates cognitive impairments in aging mice. 2. File List: File 1 Name: 1.Percentage of correct choices-Learning phase File 1 Description: Percentage of correct choices made by mice during learning phase of eight arm radial maze test File 2 Name: 2.Working memory error File 2 Description: Number of working memory errors made by mice during trial phase of eight arm radial maze test File 3 Name: 3.Reference memory error File 3 Description: Number of reference memory errors made by mice during trial phase of eight arm radial maze test File 4 Name: 4.Percentage of correct choices-Retention phase File 4 Description: Percentage of correct choices made by mice during retention phase of eight arm radial maze test File 5 Name: 5.Visits to familiar object File 5 Description: Number of visits to familiar object made by mice during the test phase of novel object recognition test File 6 Name: 6.Visits to novel object File 6 Description: Number of visits to novel object made by mice during the test phase of novel object recognition test METHODOLOGICAL INFORMATION Spatial working and reference memory were assessed using an eight-arm radial maze test and cognition using a novel object recognition test (NORT) DATA-SPECIFIC INFORMATION FOR: 1.Percentage of correct choices-Learning phase 1. Number of variables: 5 2. Number of cases/rows: 36 3. Variable List: Groups: mice groups Day 1 to Day 4 : Mean percentage of correct choices made by mice during learning phase of eight arm radial maze test 4. Missing data codes: None 5. Abbreviations used: NAC; Normal Aged Control, SVC; Saline Vehicle Control, HIHEK-CM; Heat Inactivated Human Embryonic Kidney stem cell Condititioned Media, EE; Environmental Enrichment, Ch-DHA; Choline and Docosahexaenoic Acid, HEK-CM; Human Embryonic Kidney stem cell Condititioned Media DATA-SPECIFIC INFORMATION FOR: 2.Working memory error 1. Number of variables: 5 2. Number of cases/rows: 36 3. Variable List: Groups: mice groups Day 1 to Day 4 : Mean number of working memory errors during learning phase of eight arm radial maze test 4. Missing data codes: None 5. Abbreviations used: NAC; Normal Aged Control, SVC; Saline Vehicle Control, HIHEK-CM; Heat Inactivated Human Embryonic Kidney stem cell Condititioned Media, EE; Environmental Enrichment, Ch-DHA; Choline and Docosahexaenoic Acid, HEK-CM; Human Embryonic Kidney stem cell Condititioned Media DATA-SPECIFIC INFORMATION FOR: 3.Reference memory error 1. Number of variables: 5 2. Number of cases/rows: 36 3. Variable List: Groups: mice groups Day 1 to Day 4 : Mean number of reference memory errors during learning phase of eight arm radial maze test 4. Missing data codes: None 5. Abbreviations used: NAC; Normal Aged Control, SVC; Saline Vehicle Control, HIHEK-CM; Heat Inactivated Human Embryonic Kidney stem cell Condititioned Media, EE; Environmental Enrichment, Ch-DHA; Choline and Docosahexaenoic Acid, HEK-CM; Human Embryonic Kidney stem cell Condititioned Media DATA-SPECIFIC INFORMATION FOR: 4.Percentage of correct choices-Retention phase 1. Number of variables: 2 2. Number of cases/rows: 36 3. Variable List: Groups: mice groups % of correct choices: Mean Percentage of correct choices made by mice during retention day of eight arm radial maze test 4. Missing data codes: None 5. Abbreviations used: NAC; Normal Aged Control, SVC; Saline Vehicle Control, HIHEK-CM; Heat Inactivated Human Embryonic Kidney stem cell Condititioned Media, EE; Environmental Enrichment, Ch-DHA; Choline and Docosahexaenoic Acid, HEK-CM; Human Embryonic Kidney stem cell Condititioned Media DATA-SPECIFIC INFORMATION FOR: 5.Visits to familiar object 1. Number of variables: 2 2. Number of cases/rows: 30 3. Variable List: Groups: mice groups Number of visits to familiar object: Mean number of visits to familiar object made by mice during the test phase of novel object recognition test 4. Missing data codes: None 5. Abbreviations used: NAC; Normal Aged Control, HIHEK-CM; Heat Inactivated Human Embryonic Kidney stem cell Condititioned Media, EE; Environmental Enrichment, Ch-DHA; Choline and Docosahexaenoic Acid, HEK-CM; Human Embryonic Kidney stem cell Condititioned Media DATA-SPECIFIC INFORMATION FOR: 6.Visits to novel object 1. Number of variables: 2 2. Number of cases/rows: 30 3. Variable List: Groups: mice groups Number of visits to novel object: Mean number of visits to novel object made by mice during the test phase of novel object recognition test 4. Missing data codes: None 5. Abbreviations used: NAC; Normal Aged Control, HIHEK-CM; Heat Inactivated Human Embryonic Kidney stem cell Condititioned Media, EE; Environmental Enrichment, Ch-DHA; Choline and Docosahexaenoic Acid, HEK-CM; Human Embryonic Kidney stem cell Condititioned Media