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Data from: Foraging-induced craniofacial plasticity is associated with an early, robust, and dynamic transcriptional response

Tetrault, Emily1; Aaronson, Ben1; Gilbert, Michelle2; Albertson, Craig1

Published Mar 24, 2024 on Dryad. https://doi.org/10.5061/dryad.0gb5mkm8f

Data files

Mar 24, 2024 version files 81.36 KB

Abstract

Phenotypic plasticity is the ability of a single genotype to vary its phenotype in response to the environment. Plasticity of the skeletal system in response to mechanical input is widely studied, but the timing of its transcriptional regulation is not well-understood. Here we used the cichlid feeding apparatus to examine the transcriptional dynamics of skeletal plasticity over time. Using three closely related species that vary in their ability to remodel bone and a panel of 11 genes, including well studied skeletal differentiation markers and newly characterized environmentally sensitive genes, we examined plasticity at 1, 2, 4 and 8 weeks following the onset of alternate foraging challenges. We found that the plastic species exhibited environment-specific bursts in gene expression at 1 week, followed by a sharp decline in levels, while the species with more limited plasticity exhibited consistently low levels of gene expression. This trend held across nearly all genes, suggesting that it is a hallmark of the larger plasticity regulatory network. We conclude that plasticity of the cichlid feeding apparatus is not the result of slowly accumulating gene expression difference over time, but rather is stimulated by early bursts of environment-specific gene expression followed by a return to homeostatic levels.