Data from: Evolution of personal and social immunity in the context of parental care
Ziadie, Michelle A., University of Georgia
Ebot-Ojong, Felicia, University of Georgia
McKinney, Elizabeth C., University of Georgia
Moore, Allen J., University of Georgia
Published Sep 24, 2018 on Dryad.
Cite this dataset
Ziadie, Michelle A.; Ebot-Ojong, Felicia; McKinney, Elizabeth C.; Moore, Allen J. (2018). Data from: Evolution of personal and social immunity in the context of parental care [Dataset]. Dryad. https://doi.org/10.5061/dryad.17qn634
Social immunity moderates the spread of pathogens in social groups and is especially likely in groups structured by genetic relatedness. The extent to which specific immune pathways are used is unknown. Here, we investigate the expression and social role of three functionally separate immune genes (pgrp-sc2, thaumatin, and defensin) during parental care in the beetle Nicrophorus vespilloides. These genes reside in different immune pathways, allowing us to test if specific components of the immune system are targeted for social immunity. To test for the evolution of specificity we manipulated the influence of social context and timing on gene expression and quantified the covariance of maternal immune gene expression and offspring fitness. Larvae reduced expression of all three genes in the presence of parents. Parental pgrp-sc2 and thaumatin increased during direct parenting, while defensin was upregulated before larvae arrived. Parental expression of pgrp-sc2 and thaumatin responded similarly to experimental manipulation of timing and presence of larvae, which differed from the response of defensin. We found a positive covariance between maternal expression and offspring fitness for pgrp-sc2 and thaumatin, but not defensin. We suggest that social immunity can involve specific genes and pathways, which reflects evolution as an interacting phenotype during parenting.
Immune gene expression in larvae with and without parents
Data used to compare gene expression of larvae, measured with qRT-PCR, when parents are present and when they are absent. Used to generate fig 2 in Ziadie et al.
Expression of pgrp-sc2, thaumatin and defensin under different social conditions for females.
Gene expression data, used to generate figure 4, measured by qRT-PCR.
Fitness effects in offspring arising from immune gene expression in mother during parenting.
National Science Foundation, Award: IOS-1354358; DGE-1443117