Data from: The genetic architecture of growth rate in juvenile Takifugu species.
Data files
Aug 10, 2012 version files 95.50 KB
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Allelic effect.xls
17.41 KB
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genetic map.zip
21.45 KB
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QTL.zip
12.53 KB
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README_for_genetic map.txt
367 B
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README_for_QTL.txt
226 B
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SL of original species.xls
43.52 KB
Abstract
Closely related species have often evolved dramatic differences in body size. Takifugu rubripes (fugu) is a large marine pufferfish whose genome has been sequenced, whereas T. niphobles is the smallest species among Takifugu. We show that, unsurprisingly, the juvenile growth rate of T. rubripes is higher than that of T. niphobles in a laboratory setting. We produced F2 progenies of their F1 hybrids and found one quantitative trait locus (QTL) significantly associated with variation in juvenile body size. This QTL region (3.5 Mb) contains no known genes directly related to growth phenotype (such as IGFs) except Fgf21, which inhibits growth hormone signaling in mouse. The QTL in Takifugu spp. is distinct from the region previously known to control body size variations in stickleback or tilapia. Our results suggest that in the fish tested herein, genomic regions underlying body size evolution might have different genetic origins. They also suggest that many diverse traits in Takifugu spp. are amenable to genetic mapping.