Data from: A cell-based mechanical model of coronary artery tunica media
Melnikova, Natalia B.; Svitenkov, Andrew I.; Hose, D. Rod; Hoekstra, Alfons G. (2018), Data from: A cell-based mechanical model of coronary artery tunica media, Dryad, Dataset, https://doi.org/10.5061/dryad.2t208
A three-dimensional cell-based mechanical model of coronary artery tunica media is proposed. The model is composed of spherical cells forming a hexagonal close-packed lattice. Tissue anisotropy is taken into account by varying interaction forces with the direction of intercellular connection. Several cell-centre interaction potentials for repulsion and attraction are considered, including the Hertz contact model and its neo-Hookean extension, the Johnson–Kendall–Roberts model of adhesive contact, and a wormlike chain model. The model is validated against data from in vitro uni-axial tension tests performed on dissected strips of tunica media. The wormlike chain potential in combination with the neo-Hookean Hertz contact model produces stress–stretch curves which represent the experimental data very well.