Data from: A non-parametric analytic framework for within-host viral phylogenies and a test for HIV-1 founder multiplicity
Lewitus, Eric; Rolland, Morgane (2019), Data from: A non-parametric analytic framework for within-host viral phylogenies and a test for HIV-1 founder multiplicity, Dryad, Dataset, https://doi.org/10.5061/dryad.33m05qb
Boxplots for maximum pairwise genetic dissimilarity for alignments simulated under various (left) dN/dS, (middle) γ distributions, and (right) ti/tv. Dashed lines indicate pairwise significant differences in mean values (P < 0.05).
A heuristic test for founder heterogeneity on time-scaled trees. (A) Boxplot of lnλ∗ for acutely infected participants with founder homogeneity (green) and heterogeneity (brown) (Keele et al. 2008). (B) Density plot of lnλ∗ for all participants, nominally colored to show which tails of the distribution are predominantly occupied by participants with founder homogeneity and heterogeneity. (C) Barplot of lnλ∗, adjusted so that the minimum value is zero. Fill colors represent the inferred classification based on the λ∗ test of founder heterogeneity; border colors represent the classification given in (Keele et al. 2008). ±σ2/2 of the median are shown with dashed lines on (B,C).