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Behavioral and ephys data of research paper: Microsecond interaural time difference discrimination restored by cochlear implants after neonatal deafness

Citation

Rosskothen-Kuhl, Nicole; Buck, Alexa N; Li, Kongyan; Schnupp, Jan W (2021), Behavioral and ephys data of research paper: Microsecond interaural time difference discrimination restored by cochlear implants after neonatal deafness, Dryad, Dataset, https://doi.org/10.5061/dryad.573n5tb6d

Abstract

The uploaded raw behavioral and electrophysiological data form the basis for our research study on "Microsecond Interaural Time Difference Discrimination Restored by Cochlear Implants After Neonatal Deafness". Based on this data we were able to show that neonatally deafened (ND) rats provided with precisely synchronized cochlear implant stimulation in adulthood can be trained to lateralize interaural time differences (ITDs) with essentially normal behavioral thresholds near 50 μs. Furthermore, comparable ND rats show high physiological sensitivity to ITDs immediately after binaural implantation in adulthood.

In addition to the raw data, we provided scripts to analyze the psychometric functions for the ITD sensitivity of our acoustically or electrically stimulated rats (see Fig. 1 of the manuscript). To reproduce the analysis of the electrophysiological data (see Figs. 3+4 of the manuscript), various analysis scripts were added in addition to the raw data. For a detailed description of the data analysis of these data, see section "Data analysis" of the Methods section of our manuscript.

 

Funding

Deutscher Akademischer Austauschdienst (DAAD): Nicole Rosskothen-Kuhl, P.R.I.M.E. - Postdoctoral Researchers International Mobility Experience, Award: REA grant agreement n 605728

Hong Kong General Research Fund, Award: 11100219

Hong Kong Medical Research Fund , Award: 06172296

Shenzhen Science and Innovation Fund, Award: JCYJ20180307124024360

Baden-Wuerttemberg Ministry of Science, Award: Research and Art and the University of Freiburg in the funding programme Open Access Publishing.

Hong Kong General Research Fund, Award: 11100219

Hong Kong Medical Research Fund, Award: 6172296

Shenzhen Science and Innovation Fund, Award: JCYJ20180307124024360

Baden-Wuerttemberg Ministry of Science, Award: Research and Art and the University of Freiburg in the funding programme Open Access Publishing.