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Data from: New Crystal Forms and Amorphous Phase of Sophoricoside: X-Ray Structures and Characterization

Citation

Xing, Cheng et al. (2019), Data from: New Crystal Forms and Amorphous Phase of Sophoricoside: X-Ray Structures and Characterization, Dryad, Dataset, https://doi.org/10.5061/dryad.5qd036v

Abstract

Sophoricoside, which is an isoflavone glycoside found in many plant species, has recently attracted attention because of its anti-fertility activity. One solvent-free form, two solvatomorphs and an amorphous phase of sophoricoside are reported for the first time. X-ray diffractometry, differential scanning calorimetry, thermal gravimetric analysis and Fourier-transform infrared spectroscopy were used to characterize the different forms. The results show that factors such as crystal symmetry, intermolecular arrangement, conformational flexibility, hydrogen-bonding interactions and solvent incorporation lead to different solid-state forms. An investigation of the transformations of the four forms showed that they can interconvert with each other under certain conditions. Amorphous phase and solvatomorphism were unstable but can improve the solubility of sophoricoside in water.

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