Data from: Label-free sensitive detection of influenza virus using PZT discs with a synthetic sialylglycopolymer receptor layer
Data files
Aug 29, 2019 version files 7.95 MB
-
10_5_vp_ml-1.spm
946.17 KB
-
10_5_vp_ml-2.spm
789.53 KB
-
10_5_vp_ml-3.spm
952.49 KB
-
10_6_vp_ml-1.spm
772 KB
-
10_6_vp_ml-2.spm
879.20 KB
-
10_6_vp_ml-3.spm
534.47 KB
-
10_7_vp_ml.spm
931.02 KB
-
Description of files.doc
32.26 KB
-
V6_106.009
1.06 MB
-
V6_106.010
1.06 MB
Abstract
We describe rapid, label-free detection of Influenza A viruses using the first radial mode of oscillations of lead zirconate titanate (PZT) piezoelectric disks with a 2-mm radius and 100-µm thickness fabricated from a piezoelectric membrane. The disks are modified with a synthetic sialylglycopolymer receptor layer,and the coated disks are inserted in a flowing virus suspension. Label-free detection of the virus is achieved by monitoring the disk radial mode resonance frequency shift. Piezo transducers with sialylglycopolymer sensor layers exhibited a long lifetime, a high sensitivity, and the possibility of regeneration. We demonstrate positive, label-free detection of Influenza A viruses at concentrations below 10^5 virus particles per millilitre. We show that label-free, selective, sensitive detection of Influenza viruses by home appliances is possible in principle.