Data from: Molecular genetics of sex identification, breed ancestry and polydactyly in the Norwegian Lundehund breed
Kropatsch, Regina et al. (2015), Data from: Molecular genetics of sex identification, breed ancestry and polydactyly in the Norwegian Lundehund breed, Dryad, Dataset, https://doi.org/10.5061/dryad.67sj1
The Norwegian Lundehund breed of dog has undergone a severe loss of genetic diversity as a result of inbreeding and epizootics of canine distemper. As a consequence, the breed is extremely homogeneous and accurate sex identification is not always possible by standard screening of X-chromosomal loci. To improve our genetic understanding of the breed we genotyped 17 individuals using a genome-wide array of 170 000 single nucleotide polymorphisms (SNPs). Standard analyses based on expected homozygosity of X-chromosomal loci failed in assigning individuals to the correct sex, as determined initially by physical examination and confirmed with the Y-chromosomal marker, amelogenin. This demonstrates that identification of sex using standard SNP assays can be erroneous in highly inbred individuals.