Data from: modifying cellulose fibers with carbon dots: a promising approach for development of antimicrobial fibers
Data files
Mar 12, 2024 version files 127.31 KB
-
1)_Data_for_FIGURE_1.xlsx
69.76 KB
-
2)_Data_for_FIGURE_6.xlsx
15.13 KB
-
3)_Data_for_FIGURE_7.xlsx
10.26 KB
-
4)_Data_for_FIGURE_8.xlsx
9.80 KB
-
5)_Data_for_FIGURE_10.xlsx
10.50 KB
-
6)_Data_for_FIGURE_11.xlsx
9.85 KB
-
README.md
2.01 KB
Abstract
This study focuses on the development of antimicrobial fibers for use in medical and healthcare textile industries. Carbon dots (CDs) were designed with boronic acid groups to attach to cellulose fibers found in cotton textiles and enhance their attachment to glycogens on bacterial surfaces. Boronic acid- (BACD) and curcumin-based CDs (PBA-CCMCD) were prepared and characterized using various techniques, showing a nanoscale size and zeta potential values. The CDs inhibited the growth of both Staphylococcus epidermidis and Escherichia coli bacteria, with UV-activated CDs demonstrating improved antibacterial activity. The antimicrobial activity of the CDs was then tested, revealing strong adherence to the cellulose paper fibers with no CD diffusion and potent inhibition of bacterial growth. Cytotoxicity assays on human cell lines showed no toxicity towards cells at concentrations up to 100 µg/mL, but exhibited increased toxicity at concentrations exceeding 1000 µg/mL. However, CD-modified cellulose paper fibers showed no toxicity against human cell lines, highlighting the antimicrobial properties of the CD-modified cellulose fibers as safe for human use. The findings show promising potential for applications in both industrial and clinical settings.
README: Data from: modifying cellulose fibers with carbon dots: a promising approach for development of antimicrobial fibers
https://doi.org/10.5061/dryad.6hdr7sr71
Description of the data and file structure
1) Absorption and Emission properties of CDs. (File: Data_for_FIGURE_1)
Absorption and emission spectra of BACDs (Figure 1A) and PBA-CCMCDs (Figure 1B) in PBS buffer (pH 7.4). The fluorescence with the aqueous solutions of CDs in PBS excited at 270 nm for BACDs and 315 nm for PBA-CCMCDs.
2) Quantification of the inhibitory concentrations of CDs (File: Data_for_FIGURE_6)
Relative growth of bacteria to control in wells of the control and CD-treated bacterial cell suspension at different CD concentrations based on absorbance values (A600).
3) Quantification of the inhibitory effect of BACD-modified paper discs (File: Data_for_FIGURE_7)
Relative growth of bacteria to control in wells of the control and modified-disc treated bacterial cell suspension at CFU concentrations based on absorbance values (A600). a) Staphylococcus epidermidis (SE) b) Escherichia coli (E.coli).
4) Quantification of the inhibitory effect of PBA-CCMCD-modified paper discs (File: Data_for_FIGURE_8)
Relative growth of bacteria to control in wells of the control and modified-disc treated bacterial cell suspension at CFU concentrations based on absorbance values (A600). a) Staphylococcus epidermidis (SE) b) Escherichia coli (E.coli).
5) Cell culture viability with CDs: a) HBMEC and b) HCT 116 (File: Data_for_FIGURE_10)
Relative growth of cells to control in wells of the control and CD-treated cell culture based on absorbance values at 570 nm of MTT assay.
6) Cell culture viability with CD-modified paper discs: a) HBMEC and b) HCT 116 (File: Data_for_FIGURE_11)
Relative growth of cells to control in wells of the control and CD-treated cell culture based on absorbance values at 570 nm of MTT assay.