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Data from: Race/Ethnicity Influences Outcomes in Young Adults with Intracerebral Hemorrhage


Miyares, Laura C et al. (2020), Data from: Race/Ethnicity Influences Outcomes in Young Adults with Intracerebral Hemorrhage, Dryad, Dataset,


Objectives: We investigated the predictors of functional outcome in young patients enrolled in a multi-ethnic study of intracerebral hemorrhage (ICH). Methods: The Ethnic/Racial Variations in Intracerebral Hemorrhage (ERICH) study is a prospective multi-center study of ICH among adult (age ≥18 years) non-Hispanic whites, non-Hispanic blacks, and Hispanics. The study recruited 1000 participants per racial/ethnic group. The present study utilized the subset of ERICH cases aged <50 years with supratentorial ICH. Functional outcome was ascertained using the modified Rankin Scale (mRS) at 3 months. Logistic regression was used to identify factors associated with poor outcome (mRS 4–6), and analyses were compared by race/ethnicity to identify differences across these groups. Results: Of the 3000 ICH cases enrolled in ERICH, 418 were studied (mean age 43 years, 69% male), of which 48 (12%) were white, 173 (41%) were black, and 197 (47%) were Hispanic. For supratentorial ICH, blacks (odds ratio [OR] 0.42, p=0.046) and Hispanics (OR 0.34, p=0.01) had better outcomes than whites after adjustment for other factors associated with poor outcome: age, baseline disability, admission blood pressure, admission Glasgow Coma Scale score, ICH volume, deep ICH location, and intraventricular extension. Conclusions: In young patients with supratentorial ICH, black and Hispanic race/ethnicity is associated with better functional outcomes, compared with white race. Additional studies are needed to identify the biological and social mediators of this association.

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