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FASTA sequences of 6 different proteins of SARS-CoV-2

Citation

Khan, Umama; Khan, Md. Salauddin; Debnath, Pinky (2021), FASTA sequences of 6 different proteins of SARS-CoV-2, Dryad, Dataset, https://doi.org/10.5061/dryad.7pvmcvdt0

Abstract

The acute respiratory disease induced by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) has become a global epidemic in just less than a year by the first half of 2020. The subsequent efficient human-to-human transmission of this virus eventually affected millions of people worldwide. The virulence of the SARS-CoV-2 is mostly regulated by its proteins but very little is known about the protein structures and functionalities. Therefore, the main purpose of this study is to learn more about these proteins through bioinformatics approaches. In this study, ORF10, ORF7b, ORF7a, ORF6, membrane glycoprotein, and envelope protein have been selected from a Bangladeshi Corona-virus strain G039392 and a number of bioinformatics tools and strategies were implemented for multiple sequence alignment and phylogeny analysis with 9 different variants, predicting hydropathicity, amino acid compositions, protein-binding propensity, protein disorders, 2D and 3D protein modeling.