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Atlas of impact-induced, in vivo human brain kinematics

Citation

Gomez, Arnold et al. (2021), Atlas of impact-induced, in vivo human brain kinematics, Dryad, Dataset, https://doi.org/10.5061/dryad.8cz8w9gpv

Abstract

Accelerations cause brain tissue to move, and this data summarizes MRI-based observations of 3D brain movement during an in vivo impact (brain-skull displacement and brain tissue deformation). The data is a group average, or atlas, of indivudial data from two groups of study participants: neck extension (n=10) and neck rotation (n=9).

Methods

Brain tissue motion data was extracted from MRI sequences acquired while the heads of study participatns were subjected to a mild acceleration inside the MRI scanner.  The resulting resulting images were processed using a tissue tracking algorithm. The output of the algorithm consisted of skull-brain displacements and strains in each of the participants. This data consists of a group average across the individuals i.e., a representative movement pattern of displacement and strain, as well as its varability.

Usage Notes

READ ME

Atlas (a group average) of brain motion data acquired via MRI during a mild acceleration of human heads. Two folders are given: one for an impact during neck rotation and one impact during neck extension. The data is in ascii format that can be read by humans or machines. The software that may be used for visualization appears below. Each vtk file contains the following fields defined in a mesh with nodal and cell data:

1) Mesh locations (float 3d vector stored as 'unstructured_grid')
2) Mesh connectivity (integer scalar 4d connectivity vector 'cells')
3) Atlas MRI T1-weighted magnitude (scalar stored at the nodes 'T1')
3) Group variability in MRI T1-weighted magnitude (scalar stored at the nodes 'T1_std')
4) Atlas Displacement (3d vector time sequence stored at the nodes 'disp')
5) Group variability in Displacement (3d vector time sequence stored at the nodes 'disp_std')
6) Atlas Strain tensor (6d vector time sequence stored at the cells 'E1')
7) Max shear strain from atlas strain tensor (scalar time sequence stored at the cells 'GmaxT2')
8) Variability in Max shear strain (scalar time sequence stored at the cells 'GmaxT2_std')
9) Group average of individual max shear strains (scalar time sequence stored at the cells 'GmaxT3')
10) Variability Group average of individual max shear strains (scalar time sequence stored at the cells 'GmaxT3_std')


A description of the vtk format appears here:
https://vtk.org/wp-content/uploads/2015/04/file-formats.pdf

Descriptions of visualization software appear here:
https://en.wikipedia.org/wiki/ParaView
https://en.wikipedia.org/wiki/VisIt

Funding

National Institute of Neurological Disorders and Stroke, Award: R01/R56-NS055951

National Institute of Neurological Disorders and Stroke, Award: U01 NS112120