Objective: To summarize the clinical characteristics of patients with ocular chemical injuries and evaluate their potential relationship with the visual outcome by analyzing the medical records of these patients from January 1, 2012, to December 31, 2017. Design: A retrospective case series study. Setting: Jinshan Hospital of Fudan University in Shanghai. Methods: Patient data included age, gender, occupational classification, location of ocular chemical injury, initial and final best-corrected distance visual acuity (BCDVA), intraocular pressure (IOP), nature and chemical phase, distribution and severity of chemical injury, management methods, and complications. All variables were evaluated for their potential relationship with visual outcome. Results: A total of 160 patients were hospitalized with ocular chemical injuries. The majority of the patients were factory workers and arrived at the consultation room less than 24 hours after injury. The most common ocular injury setting, classification of severity, causative chemical, chemical phase, and complications were workplace, grade Ⅱ, unknown and mixed substance, liquid, and elevated IOP, respectively. Initial BCDVA was significantly worse in the solid group than in the liquid group (P = 0.009). The risk factors for poor final BCDVA were identified as older age, poor initial BCDVA, and irrigation 24 hours after injury (P < 0.001, P < 0.001, and P = 0.011, respectively). Conclusion: We elaborate the clinical characteristics and outcomes of patients with ocular chemical injuries in Jinshan District, Shanghai. A comprehensive education program should be established and the use of protective eyewear should be promoted to prevent occupation-related ocular chemical injuries.