Data from: Rapid transporter regulation prevents substrate flow traffic jams in boron transport
Data files
Aug 18, 2018 version files 2.22 GB
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NIP51_Int1570_mRNA670_ (1).czi
115.05 MB
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NIP51_Int1570_mRNA670_ (10).czi
94.57 MB
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NIP51_Int1570_mRNA670_ (2).czi
111.90 MB
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NIP51_Int1570_mRNA670_ (3).czi
64.66 MB
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NIP51_Int1570_mRNA670_ (4).czi
63.09 MB
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NIP51_Int1570_mRNA670_ (5).czi
64.66 MB
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NIP51_Int1570_mRNA670_ (6).czi
78.84 MB
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NIP51_Int1570_mRNA670_ (7).czi
55.22 MB
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NIP51_Int1570_mRNA670_ (8).czi
129.21 MB
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NIP51_Int1570_mRNA670_ (9).czi
104.02 MB
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NIP51mRNA670_PP2AmRNA570_(1).czi
80.38 MB
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NIP51mRNA670_PP2AmRNA570_(10).czi
94.57 MB
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NIP51mRNA670_PP2AmRNA570_(11).czi
126.08 MB
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NIP51mRNA670_PP2AmRNA570_(12).czi
115.04 MB
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NIP51mRNA670_PP2AmRNA570_(13).czi
108.73 MB
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NIP51mRNA670_PP2AmRNA570_(2).czi
80.38 MB
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NIP51mRNA670_PP2AmRNA570_(3).czi
119.77 MB
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NIP51mRNA670_PP2AmRNA570_(4).czi
108.76 MB
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NIP51mRNA670_PP2AmRNA570_(5).czi
111.90 MB
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NIP51mRNA670_PP2AmRNA570_(6).czi
89.85 MB
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NIP51mRNA670_PP2AmRNA570_(7).czi
118.19 MB
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NIP51mRNA670_PP2AmRNA570_(8).czi
96.15 MB
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NIP51mRNA670_PP2AmRNA570_(9).czi
86.69 MB
Abstract
Nutrient uptake by roots often involves substrate-dependent regulated nutrient transporters. For robust uptake, the system requires a regulatory circuit within cells and a collective, coordinated behaviour across the tissue. A paradigm for such systems is boron uptake, known for its directional transport and homeostasis, as boron is essential for plant growth but toxic at high concentrations. In Arabidopsis thaliana Boron up- take occurs via diffusion facilitators (NIPs) and exporters (BORs), each presenting distinct polarity. Intriguingly, although boron soil concentrations are homogenous and stable, both transporters manifest strikingly swift boron-dependent regulation. Through mathematical modelling, we demonstrate that slower regulation of these transporters leads to physiologically detrimental oscillatory behaviour. Cells become periodically exposed to potentially cytotoxic boron levels, and nutrient throughput to the xylem becomes hampered. We conclude that, while maintaining homeostasis, swift transporter regulation within a polarised tissue context is critical to prevent intrinsic traffic-jam like behaviour of nutrient flow.