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Effects of cold or warm ischemia and ex-vivo lung perfusion on the release of damage associated molecular patterns and inflammatory cytokines in experimental lung transplantation

Citation

Parapanov, Roumen et al. (2022), Effects of cold or warm ischemia and ex-vivo lung perfusion on the release of damage associated molecular patterns and inflammatory cytokines in experimental lung transplantation, Dryad, Dataset, https://doi.org/10.5061/dryad.9s4mw6mj3

Abstract

Lung transplantation (LTx) is associated with sterile inflammation, possibly related to the release of damage associated molecular patterns (DAMPs) by injured allograft cells. We have measured cellular damage and the release of DAMPs and cytokines in an experimental model of LTx after cold or warm ischemia and examined the effect of pretreatment with ex-vivo lung perfusion (EVLP).

Funding

Swiss National Fund for Scientific Research, Award: 310030_172975*

Swiss National Fund for Scientific Research, Award: 310030_188525*