This was a cross-sectional nationwide survey of adults in the US in 2021. The survey targeted a representative sample of US adults. The rate of psychedelic us, comorbid conditions, mental and physical health, and factors predictive of psychedlic use were assessed.

Data was collected through an on-line cross-sectional survey of adults (18 years or older) in the US. The survey was conducted in accordance with Acumen Health Research Institute's (AHRI) established SOPs. A random stratified sampling framework ensured a community-based sample with a demographic composition representative of the US adult population by region, gender, age, and race, according to the US Census (US Census American Community Survey 5-year estimate, 2011-2015). To participate in the study, respondents were required to be 18 years old or older, reside in the United States, and confirm their voluntarily agreement to participate (participants were informed they could leave the survey at any time). The survey was open to the general population. Participants were recruited through AHRI’s online research panels. Analysis was carried out with SPSS v27.0.1.0.

See ReadMe file (code book).