Identifying key traits that can serve as proxies for species drought resistance is crucial for predicting and mitigating effects of climate change in diverse plant communities. Turgor loss point (π_tlp) is a recently emerged trait that has been linked to species distributions across gradients of water availability. However, a direct relationship between π_tlp and species ability to survive drought has yet to be established for woody species. Using a manipulative field experiment to quantify species drought resistance (i.e. their survival response to drought), combined with measurements of π_tlp for 16 tree species, we show a negative relationship between π_tlp and seedling drought resistance. Using long-term forest plot data, we also show that π_tlp predicts seedling survival responses to a severe El Niño-related drought, although additional factors are clearly also important. Our study demonstrates that species with lower π_tlp exhibit higher survival under both experimental and natural drought. These results provide a missing cornerstone in the assessment of the traits underlying drought resistance in woody species and strengthen π_tlp as a proxy for evaluating which species will lose or win under projections of exacerbating drought regimes.