Skip to main content
Dryad logo

Data from: Active information maintenance in working memory by a sensory cortex

Citation

Zhang, Xiaoxing et al. (2019), Data from: Active information maintenance in working memory by a sensory cortex, Dryad, Dataset, https://doi.org/10.5061/dryad.dt5h4m1

Abstract

Working memory is a critical brain function for maintaining and manipulating information over delay periods of seconds. It is debated whether delay-period neural activity in sensory regions is important for the active maintenance of information during the delay period. Here, we tackle this question by examining the anterior piriform cortex (APC), an olfactory sensory cortex, in head-fixed mice performing several olfactory working memory tasks. Active information maintenance is necessary in these tasks, especially in a dual-task paradigm in which mice are required to perform another distracting task while actively maintaining information during the delay period. Optogenetic suppression of neuronal activity in APC during the delay period impaired performance in all the tasks. Furthermore, electrophysiological recordings revealed that APC neuronal populations encoded odor information in the delay period even with an intervening distracting task. Thus, delay activity in APC is important for active information maintenance in olfactory working memory.

Usage Notes

Dataset accompanying : Zhang X. et. al., Active information maintenance in working memory by a sensory cortex

This file contained the essential dataset that accompany: Zhang, X, et.al., Active information maintenance in working memory by a sensory cortex dataset: behavior These are the behavior records of mice performing working memory tasks, sorted by mice id and date of experiment. The files are either in plain .txt format, or in a Java serialized object file format (.ser). The detailed computer program codes for interpretation and parsing of these files are published on Github (https://github.com/wwweagle/). dataset: ephys These are the essential electro-physiology extra-cellular single unit recording files of mice performing working memory tasks, sorted by mice id and date of experiment. The files are in Matlab .mat format. The detailed computer program codes for interpretation and parsing of these files are published on Github (https://github.com/wwweagle/).

Active.information.maintenance.in.working.memory.by.a.sensory.cortex.zip

Additional behavioral data

Additional behavioral data produced during eLife 2019 revision.

behavior_part2.zip

Raw trace data file

EphysRawTrace.zip