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Dryad

RNAseq data of iRECs treated with palmitic acid and oleic acid

Data files

Abstract

In diabetic patients, dyslipidemia frequently contributes to organ damage such as diabetic kidney disease (DKD). DKD is associated with excessive renal deposition of triacylglycerol (TAG) in lipid droplets (LD). In order to understand the biological processes ocurring in proximal tubules when exposed to fatty acids, we performed a comparative transcriptomic study on BSA-, BSA-PA-, BSA-OA- and BSA-PA/OA-treated iRECs using RNA sequencing.