Ni-Ce three-dimensional material with macropore diameter of 146.6±8.4 nm were synthesized and used for methanation catalyst. Firstly, H2-reduction of catalyst was conducted in thermal fixed bed and plasma reactor respectively, then X-ray diffraction (XRD) and CO2 Temperature Programmed Desorption (TPD) experiments on the two reduced samples were carried out to reveal the plasma effect on catalyst’s physicochemical properties. It was found that plasma reduction created more abundant basic sites for CO2 adsorption, especially the medium basic sites were even doubled compared with the thermal reduced catalysts. The plasma reduced catalyst exhibited excellent low-temperature activity, ca. 50~60 oC lower than the thermal catalyst (the maximum CO2 conversion point). Based on the optimum reduced catalyst, plasma effect in the reactor level was further investigated under high gas hour space velocity (GHSV) ~50000 h-1. The plasma reactor showed higher CO2 conversion capacity and efficiency than the thermal reactor.