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Data from: The impact of host genetic diversity on virus evolution and emergence

Citation

Rodríguez-Nevado, Cristina; Lam, Tommy T-Y; Holmes, Edward C.; Pagán, Israel (2018), Data from: The impact of host genetic diversity on virus evolution and emergence, Dryad, Dataset, https://doi.org/10.5061/dryad.s59v1

Abstract

Accumulating evidence indicates that biodiversity has an important impact on parasite evolution and emergence. The vast majority of studies in this area have only considered the diversity of species within an environment as an overall measure of biodiversity, overlooking the role of genetic diversity within a particular host species. Although theoretical models propose that host genetic diversity in part shapes that of the infecting parasite population, and hence modulates the risk of parasite emergence, this effect has seldom been tested empirically. Using Rabies virus (RABV) as a model parasite, we provide evidence that greater host genetic diversity increases both parasite genetic diversity and the likelihood of a host being a donor in RABV cross-species transmission events. We conclude that host genetic diversity may be an important determinant of parasite evolution and emergence.

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