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Dryad

Amplitude modulations of cortical sensory responses in pulsatile evidence accumulation

Cite this dataset

Koay, Sue Ann (2020). Amplitude modulations of cortical sensory responses in pulsatile evidence accumulation [Dataset]. Dryad. https://doi.org/10.5061/dryad.tb2rbnzxv

Abstract

Condensed neural and behavioral data, included secondary results from model fits and analyses. This dataset contains all information required to recreate figures from the paper.

Methods

Transgenic mice expressing the calcium-sensitive fluorescent indicator GCamp6f were trained in the Accumulating Towers task and two-photon calcium imaging was performed of functionally identified primary and secondary visual cortical areas, as well as retrosplenial cortex. Regions of interest representing putative single neurons were extracted using a semi-customized demixing and deconvolution procedure. Behavioral data were separately collected by a computer that ran a virtual reality control engine, and synchronized with imaging data via a synchronization timestamp sent to the imaging computer at every graphics refresh cycle.

Funding

National Institute of Neurological Disorders and Stroke, Award: 5U01NS090541

National Institute of Neurological Disorders and Stroke, Award: 1U19NS104648