Anatomical, subset, and HIV-dependent expression of viral sensors and restriction factors
Data files
Jan 31, 2025 version files 330.89 MB
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cGAMP_PID24_PBMCs_CD4Tm.fcs
6.15 MB
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cGAMP_PID24_PBMCs_Myeloid.fcs
35.77 KB
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cGAMP_PID25_PBMCs_CD4Tm.fcs
7.12 MB
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cGAMP_PID25_PBMCs_Myeloid.fcs
26.03 KB
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cGAMP_PID27_PBMCs_CD4Tm.fcs
5.44 MB
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cGAMP_PID27_PBMCs_Myeloid.fcs
31.67 KB
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D0_PID91_PBMCs_Bcells.fcs
1.72 MB
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D0_PID91_PBMCs_CD4Tm.fcs
3.90 MB
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D0_PID91_PBMCs_CD4Tn.fcs
929.13 KB
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D0_PID91_PBMCs_CD8Tm.fcs
1.08 MB
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D0_PID91_PBMCs_CD8Tn.fcs
1.02 MB
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D0_PID91_PBMCs_Myeloid.fcs
7.28 MB
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D0_PID92_PBMCs_Bcells.fcs
899.43 KB
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D0_PID92_PBMCs_CD4Tm.fcs
4.20 MB
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D0_PID92_PBMCs_CD4Tn.fcs
3.29 MB
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D0_PID92_PBMCs_CD8Tm.fcs
1.47 MB
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D0_PID92_PBMCs_CD8Tn.fcs
911.46 KB
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D0_PID92_PBMCs_Myeloid.fcs
3.83 MB
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D0_PID93_PBMCs_Bcells.fcs
305.51 KB
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D0_PID93_PBMCs_CD4Tm.fcs
4.30 MB
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D0_PID93_PBMCs_CD4Tn.fcs
2.30 MB
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D0_PID93_PBMCs_CD8Tm.fcs
1.65 MB
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D0_PID93_PBMCs_CD8Tn.fcs
1.18 MB
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D0_PID93_PBMCs_Myeloid.fcs
5.66 MB
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D0_PID94_PBMCs_Bcells.fcs
504.68 KB
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D0_PID94_PBMCs_CD4Tm.fcs
3.38 MB
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D0_PID94_PBMCs_CD4Tn.fcs
3.12 MB
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D0_PID94_PBMCs_CD8Tm.fcs
853.35 KB
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D0_PID94_PBMCs_CD8Tn.fcs
875.88 KB
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D0_PID94_PBMCs_Myeloid.fcs
4.16 MB
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Fused_PID47_PBMCs_CD4Tm.fcs
9.62 MB
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Fused_PID47_PBMCs_Myeloid.fcs
90.49 KB
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Fused_PID50_PBMCs_CD4Tm.fcs
5.32 MB
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Fused_PID50_PBMCs_Myeloid.fcs
357.76 KB
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Fused_PID82_PBMCs_CD4Tm.fcs
9.15 MB
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Fused_PID82_PBMCs_Myeloid.fcs
29.82 KB
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Fused_PID90_PBMCs_CD4Tm.fcs
5.06 MB
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Fused_PID90_PBMCs_Myeloid.fcs
32.37 KB
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HIVneg_PID91_PBMCs_CD4T.fcs
4.60 MB
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HIVneg_PID91_PBMCs_Myeloid.fcs
1.37 MB
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HIVneg_PID92_PBMCs_CD4T.fcs
9.42 MB
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HIVneg_PID92_PBMCs_Myeloid.fcs
728.45 KB
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HIVneg_PID93_PBMCs_CD4T.fcs
6.77 MB
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HIVneg_PID93_PBMCs_Myeloid.fcs
1.45 MB
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HIVneg_PID94_PBMCs_CD4T.fcs
9.33 MB
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HIVneg_PID94_PBMCs_Myeloid.fcs
1.22 MB
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HIVpos_PID91_PBMCs_CD4T.fcs
71.54 KB
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HIVpos_PID91_PBMCs_Myeloid.fcs
67.96 KB
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HIVpos_PID92_PBMCs_CD4T.fcs
135.29 KB
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HIVpos_PID92_PBMCs_Myeloid.fcs
84.61 KB
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HIVpos_PID93_PBMCs_CD4T.fcs
125.30 KB
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HIVpos_PID93_PBMCs_Myeloid.fcs
31.10 KB
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HIVpos_PID94_PBMCs_CD4T.fcs
109.18 KB
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HIVpos_PID94_PBMCs_Myeloid.fcs
22.40 KB
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LastGift_PID022_BM_Bcells.fcs
361.41 KB
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LastGift_PID022_BM_CD4T.fcs
147.68 KB
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LastGift_PID022_BM_CD8T.fcs
340.03 KB
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LastGift_PID022_BM_Myeloid.fcs
240.82 KB
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LastGift_PID022_Gut_Bcells.fcs
132.70 KB
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LastGift_PID022_Gut_CD4T.fcs
49.70 KB
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LastGift_PID022_Gut_CD8T.fcs
111.63 KB
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LastGift_PID022_Gut_Myeloid.fcs
270.76 KB
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LastGift_PID022_Kidney_Bcells.fcs
10.12 KB
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LastGift_PID022_Kidney_CD4T.fcs
345.98 KB
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LastGift_PID022_Kidney_CD8T.fcs
20.25 KB
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LastGift_PID022_Kidney_Myeloid.fcs
9.96 KB
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LastGift_PID022_Liver_Bcells.fcs
9.95 KB
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LastGift_PID022_Liver_CD4T.fcs
1.27 MB
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LastGift_PID022_Liver_CD8T.fcs
272.49 KB
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LastGift_PID022_Liver_Myeloid.fcs
34.14 KB
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LastGift_PID022_LN_Bcells.fcs
19.62 KB
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LastGift_PID022_LN_CD4T.fcs
4.10 MB
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LastGift_PID022_LN_CD8T.fcs
38.95 KB
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LastGift_PID022_LN_Myeloid.fcs
9.79 KB
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LastGift_PID022_Repro_Bcells.fcs
23.75 KB
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LastGift_PID022_Repro_CD4T.fcs
262.43 KB
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LastGift_PID022_Repro_CD8T.fcs
1.05 MB
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LastGift_PID022_Repro_Myeloid.fcs
96.92 KB
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LastGift_PID022_Spleen_Bcells.fcs
15.26 KB
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LastGift_PID022_Spleen_CD4T.fcs
409.62 KB
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LastGift_PID022_Spleen_CD8T.fcs
14 KB
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LastGift_PID022_Spleen_Myeloid.fcs
16.36 KB
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LastGift_PID028_BM_Bcells.fcs
28.03 KB
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LastGift_PID028_BM_CD4T.fcs
45.65 KB
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LastGift_PID028_BM_CD8T.fcs
102.59 KB
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LastGift_PID028_BM_Myeloid.fcs
18.99 KB
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LastGift_PID028_LN_Bcells.fcs
8.57 MB
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LastGift_PID028_LN_CD4T.fcs
2.06 MB
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LastGift_PID028_LN_CD8T.fcs
396.20 KB
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LastGift_PID028_LN_Myeloid.fcs
105.74 KB
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LastGift_PID028_Spleen_Bcells.fcs
1.63 MB
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LastGift_PID028_Spleen_CD4T.fcs
197.93 KB
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LastGift_PID028_Spleen_CD8T.fcs
64.70 KB
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LastGift_PID028_Spleen_Myeloid.fcs
774.99 KB
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LastGift_PID029_Gut_Bcells.fcs
7.75 KB
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LastGift_PID029_Gut_CD8T.fcs
8.37 KB
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LastGift_PID029_Liver_Bcells.fcs
11.67 KB
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LastGift_PID029_Liver_CD4T.fcs
11.66 KB
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LastGift_PID029_Liver_CD8T.fcs
114.62 KB
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LastGift_PID029_Liver_Myeloid.fcs
22.12 KB
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LastGift_PID029_Repro_Bcells.fcs
9.17 KB
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LastGift_PID029_Repro_CD4T.fcs
12.44 KB
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LastGift_PID029_Repro_CD8T.fcs
188.88 KB
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LastGift_PID029_Repro_Myeloid.fcs
105.28 KB
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LastGift_PID029_Spleen_Bcells.fcs
14.16 KB
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LastGift_PID029_Spleen_CD4T.fcs
9.16 KB
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LastGift_PID029_Spleen_CD8T.fcs
21.33 KB
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LastGift_PID029_Spleen_Myeloid.fcs
9.02 KB
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LastGift_PID030_BM_Bcells.fcs
770.49 KB
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LastGift_PID030_BM_CD4T.fcs
156 KB
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LastGift_PID030_BM_CD8T.fcs
2.89 MB
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LastGift_PID030_BM_Myeloid.fcs
1.07 MB
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LastGift_PID030_Gut_Bcells.fcs
9.99 KB
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LastGift_PID030_Gut_CD4T.fcs
15.91 KB
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LastGift_PID030_Gut_CD8T.fcs
8.42 KB
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LastGift_PID030_Gut_Myeloid.fcs
7.81 KB
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LastGift_PID030_Heart_Bcells.fcs
7.64 KB
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LastGift_PID030_Heart_CD4T.fcs
15.90 KB
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LastGift_PID030_Heart_CD8T.fcs
19.96 KB
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LastGift_PID030_Heart_Myeloid.fcs
22.15 KB
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LastGift_PID030_Kidney_Bcells.fcs
24.05 KB
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LastGift_PID030_Kidney_CD4T.fcs
12.18 KB
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LastGift_PID030_Kidney_CD8T.fcs
50.40 KB
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LastGift_PID030_Kidney_Myeloid.fcs
61.34 KB
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LastGift_PID030_Liver_Bcells.fcs
7.49 KB
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LastGift_PID030_Liver_CD4T.fcs
11.70 KB
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LastGift_PID030_Liver_CD8T.fcs
38.22 KB
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LastGift_PID030_Liver_Myeloid.fcs
7.96 KB
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LastGift_PID030_Spleen_Bcells.fcs
13.27 KB
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LastGift_PID030_Spleen_CD4T.fcs
36.04 KB
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LastGift_PID030_Spleen_CD8T.fcs
15.29 KB
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LastGift_PID030_Spleen_Myeloid.fcs
11.55 KB
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LastGift_PID031_Gut_Bcells.fcs
5.16 KB
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LastGift_PID031_Gut_CD4T.fcs
7.36 KB
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LastGift_PID031_Gut_CD8T.fcs
25.75 KB
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LastGift_PID031_Gut_Myeloid.fcs
6.31 KB
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LastGift_PID031_Kidney_CD4T.fcs
17.63 KB
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LastGift_PID031_Kidney_CD8T.fcs
57.91 KB
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LastGift_PID031_Kidney_Myeloid.fcs
7.53 KB
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LastGift_PID031_Liver_CD4T.fcs
5.23 KB
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LastGift_PID031_Liver_CD8T.fcs
6.45 KB
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LastGift_PID031_Liver_Myeloid.fcs
5.17 KB
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LastGift_PID031_LN_CD4T.fcs
38.89 KB
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LastGift_PID031_LN_CD8T.fcs
59.56 KB
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LastGift_PID031_LN_Myeloid.fcs
5.54 KB
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LastGift_PID031_Lung_Bcells.fcs
21.28 KB
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LastGift_PID031_Lung_CD4T.fcs
236.28 KB
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LastGift_PID031_Lung_CD8T.fcs
828.93 KB
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LastGift_PID031_Lung_Myeloid.fcs
141.45 KB
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LastGift_PID031_Spleen_CD4T.fcs
5.54 KB
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LastGift_PID031_Spleen_CD8T.fcs
7.14 KB
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LastGift_PID031_Spleen_Myeloid.fcs
5.17 KB
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LastGift_PID033_Gut_Bcells.fcs
485.28 KB
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LastGift_PID033_Gut_CD4T.fcs
859.20 KB
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LastGift_PID033_Gut_CD8T.fcs
2.08 MB
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LastGift_PID033_Gut_Myeloid.fcs
557.67 KB
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LastGift_PID033_Heart_CD4T.fcs
7.95 KB
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LastGift_PID033_Heart_CD8T.fcs
9.98 KB
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LastGift_PID033_Heart_Myeloid.fcs
13.27 KB
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LastGift_PID033_Kidney_Bcells.fcs
116.42 KB
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LastGift_PID033_Kidney_CD4T.fcs
301.27 KB
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LastGift_PID033_Kidney_CD8T.fcs
1.65 MB
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LastGift_PID033_Kidney_Myeloid.fcs
512.19 KB
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LastGift_PID033_Liver_CD4T.fcs
7.96 KB
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LastGift_PID033_Liver_CD8T.fcs
14.04 KB
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LastGift_PID033_Liver_Myeloid.fcs
7.97 KB
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LastGift_PID033_Lung_Bcells.fcs
248.70 KB
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LastGift_PID033_Lung_CD4T.fcs
229.04 KB
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LastGift_PID033_Lung_CD8T.fcs
577.70 KB
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LastGift_PID033_Lung_Myeloid.fcs
24.34 MB
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LastGift_PID033_Repro_Bcells.fcs
19.78 KB
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LastGift_PID033_Repro_CD4T.fcs
353.93 KB
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LastGift_PID033_Repro_CD8T.fcs
3.85 MB
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LastGift_PID033_Repro_Myeloid.fcs
374.22 KB
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LastGift_PID033_Spleen_Bcells.fcs
8.29 KB
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LastGift_PID033_Spleen_CD4T.fcs
959.88 KB
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LastGift_PID033_Spleen_CD8T.fcs
161.32 KB
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LastGift_PID033_Spleen_Myeloid.fcs
10.17 KB
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LastGift_PID034_Gut_Bcells.fcs
523.90 KB
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LastGift_PID034_Gut_CD4T.fcs
2.25 MB
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LastGift_PID034_Gut_CD8T.fcs
8.32 MB
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LastGift_PID034_Gut_Myeloid.fcs
95.99 KB
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LastGift_PID034_Heart_Bcells.fcs
8.54 KB
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LastGift_PID034_Heart_CD4T.fcs
206.66 KB
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LastGift_PID034_Heart_CD8T.fcs
878.39 KB
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LastGift_PID034_Heart_Myeloid.fcs
399.80 KB
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LastGift_PID034_Kidney_Bcells.fcs
295.45 KB
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LastGift_PID034_Kidney_CD4T.fcs
3.70 MB
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LastGift_PID034_Kidney_CD8T.fcs
2.53 MB
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LastGift_PID034_Kidney_Myeloid.fcs
222.29 KB
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LastGift_PID034_Liver_Bcells.fcs
31.48 KB
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LastGift_PID034_Liver_CD4T.fcs
289.34 KB
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LastGift_PID034_Liver_CD8T.fcs
619.28 KB
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LastGift_PID034_Liver_Myeloid.fcs
143.80 KB
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LastGift_PID034_LN_Bcells.fcs
229.59 KB
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LastGift_PID034_LN_CD4T.fcs
8.43 MB
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LastGift_PID034_LN_CD8T.fcs
52.21 KB
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LastGift_PID034_LN_Myeloid.fcs
12.44 KB
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LastGift_PID034_Repro_Bcells.fcs
37.16 KB
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LastGift_PID034_Repro_CD4T.fcs
909.51 KB
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LastGift_PID034_Repro_CD8T.fcs
1.38 MB
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LastGift_PID034_Repro_Myeloid.fcs
160.25 KB
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LastGift_PID034_Spleen_Bcells.fcs
1.37 MB
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LastGift_PID034_Spleen_CD4T.fcs
4.92 MB
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LastGift_PID034_Spleen_CD8T.fcs
201.21 KB
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LastGift_PID034_Spleen_Myeloid.fcs
71.59 KB
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Mock_PID24_PBMCs_CD4Tm.fcs
5.43 MB
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Mock_PID24_PBMCs_Myeloid.fcs
292.02 KB
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Mock_PID25_PBMCs_CD4Tm.fcs
6.71 MB
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Mock_PID25_PBMCs_Myeloid.fcs
555.70 KB
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Mock_PID27_PBMCs_CD4Tm.fcs
3.87 MB
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Mock_PID27_PBMCs_Myeloid.fcs
271.02 KB
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README.md
14.42 KB
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Unfused_PID47_PBMCs_CD4Tm.fcs
17.55 MB
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Unfused_PID47_PBMCs_Myeloid.fcs
238.21 KB
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Unfused_PID50_PBMCs_CD4Tm.fcs
13.14 MB
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Unfused_PID50_PBMCs_Myeloid.fcs
1.01 MB
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Unfused_PID82_PBMCs_CD4Tm.fcs
19.39 MB
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Unfused_PID82_PBMCs_Myeloid.fcs
51.33 KB
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Unfused_PID90_PBMCs_CD4Tm.fcs
12.32 MB
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Unfused_PID90_PBMCs_Myeloid.fcs
119.42 KB
Abstract
The fate of a cell exposed to HIV is affected by its ability to sense the virus and restrict its replication. To explore this, we developed VIral SensOr Restriction factor-CyTOF (VISOR-CyTOF), which profiles 19 viral sensors and restriction factors (VISORs) simultaneously in single cells, and applied it to 41 post-mortem tissues from people with HIV. We found that myeloid cells, particularly those in mucosa, are well-equipped with SAMHD1 and sensors of viral capsid and DNA, while CD4+ T cells – particularly the highly-susceptible Tem subset – are not. In lymph node CD4+ Tfh, VISOR expression patterns favor HIV integration while blocking HIV gene expression, thus favoring viral latency. HIV preferentially fuses to CD4+ T cells with a permissive VISOR profile, but early induction of select VISORs by type I interferon prevents productive HIV infection. Our findings document the diverse patterns of VISOR profiles across tissues and cell subsets, and define their association with susceptibility to HIV.
README: Anatomical, subset, and HIV-dependent expression of viral sensors and restriction factors
Nadia Roan, PhD
Gladstone Institutes
University of California, San Francisco
Dates of collection: November 2019 to May 2023
Information about geographic location of data collection: San Diego Area (for Last Gift tissue donors) and San Francisco Bay Area (for PBMC donors)
HIV preferentially fuses with CD4+ T cells exhibiting a permissive VISOR profile, but early induction of specific VISORs by type I interferon inhibits productive infection. Our findings highlight the diverse VISOR patterns across tissues and cell subsets and their link to HIV susceptibility.
Included are 220 flow cytometry standard (FCS) files from 64 different CyTOF specimens. FCS files can be viewed using software used for analyzing flow cytometry or CyTOF data (e.g., FlowJo, Cytobank). The Descriptions of each file are detailed in the table below. Each file name begins with the Group category. The groups are Last Gift (from ex vivo experiments), and from the in vitro experiments, 1) baseline (D0), 2) HIV-unfused (Unfused) or HIV-fused (Fused), 3) HIV+ (HIVpos) or HIV- (HIVneg), or 4) cGAMP VLP treated (cGAMP) or mock VLP treated (Mock). This is followed by a study participant identifier (PID). Next, the Organ category indicates whether the specimen was from a tissue (bone marrow [BM], gut, kidney, liver, spleen, lymph node [LN], male reproductive tract [Repro], heart, or lung) or PBMCs. Finally, the Cell Type category indicates whether data exported correspond to: CD4+ T (CD4T), CD8+ T (CD8T), myeloid (myeloid), or B cells (Bcell). For CD4+ and CD8+ T cells, some files are further gated on memory (Tm) or naïve (Tn) subsets.
No licenses or restrictions are placed on the data.
References for methodological information:
Methods used for generating and analyzing the CyTOF datasets are similar to those described before:
https://elifesciences.org/articles/72619
https://doi.org/10.1016/j.celrep.2021.109414
https://doi.org/10.1016/j.xcrm.2020.100081
https://www.nature.com/articles/s41590-023-01724-6
Group | PID | Organ | Cell Type |
---|---|---|---|
Last Gift | PID022 | BM | CD4T |
Last Gift | PID022 | BM | CD8T |
Last Gift | PID022 | BM | Myeloid |
Last Gift | PID022 | BM | Bcell |
Last Gift | PID022 | Gut | CD4T |
Last Gift | PID022 | Gut | CD8T |
Last Gift | PID022 | Gut | Myeloid |
Last Gift | PID022 | Gut | Bcell |
Last Gift | PID022 | Kidney | CD4T |
Last Gift | PID022 | Kidney | CD8T |
Last Gift | PID022 | Kidney | Myeloid |
Last Gift | PID022 | Kidney | Bcell |
Last Gift | PID022 | Liver | CD4T |
Last Gift | PID022 | Liver | CD8T |
Last Gift | PID022 | Liver | Myeloid |
Last Gift | PID022 | Liver | Bcell |
Last Gift | PID022 | LN | CD4T |
Last Gift | PID022 | LN | CD8T |
Last Gift | PID022 | LN | Myeloid |
Last Gift | PID022 | LN | Bcell |
Last Gift | PID022 | Repro | CD4T |
Last Gift | PID022 | Repro | CD8T |
Last Gift | PID022 | Repro | Myeloid |
Last Gift | PID022 | Repro | Bcell |
Last Gift | PID022 | Spleen | CD4T |
Last Gift | PID022 | Spleen | CD8T |
Last Gift | PID022 | Spleen | Myeloid |
Last Gift | PID022 | Spleen | Bcell |
Last Gift | PID028 | BM | CD4T |
Last Gift | PID028 | BM | CD8T |
Last Gift | PID028 | BM | Myeloid |
Last Gift | PID028 | BM | Bcell |
Last Gift | PID028 | LN | CD4T |
Last Gift | PID028 | LN | CD8T |
Last Gift | PID028 | LN | Myeloid |
Last Gift | PID028 | LN | Bcell |
Last Gift | PID028 | Spleen | CD4T |
Last Gift | PID028 | Spleen | CD8T |
Last Gift | PID028 | Spleen | Myeloid |
Last Gift | PID028 | Spleen | Bcell |
Last Gift | PID029 | Gut | CD8T |
Last Gift | PID029 | Gut | Bcell |
Last Gift | PID029 | Liver | CD4T |
Last Gift | PID029 | Liver | CD8T |
Last Gift | PID029 | Liver | Myeloid |
Last Gift | PID029 | Liver | Bcell |
Last Gift | PID029 | Repro | CD4T |
Last Gift | PID029 | Repro | CD8T |
Last Gift | PID029 | Repro | Myeloid |
Last Gift | PID029 | Repro | Bcell |
Last Gift | PID029 | Spleen | CD4T |
Last Gift | PID029 | Spleen | CD8T |
Last Gift | PID029 | Spleen | Myeloid |
Last Gift | PID029 | Spleen | Bcell |
Last Gift | PID030 | BM | CD4T |
Last Gift | PID030 | BM | CD8T |
Last Gift | PID030 | BM | Myeloid |
Last Gift | PID030 | BM | Bcell |
Last Gift | PID030 | Gut | CD4T |
Last Gift | PID030 | Gut | CD8T |
Last Gift | PID030 | Gut | Myeloid |
Last Gift | PID030 | Gut | Bcell |
Last Gift | PID030 | Heart | CD4T |
Last Gift | PID030 | Heart | CD8T |
Last Gift | PID030 | Heart | Myeloid |
Last Gift | PID030 | Heart | Bcell |
Last Gift | PID030 | Kidney | CD4T |
Last Gift | PID030 | Kidney | CD8T |
Last Gift | PID030 | Kidney | Myeloid |
Last Gift | PID030 | Kidney | Bcell |
Last Gift | PID030 | Liver | CD4T |
Last Gift | PID030 | Liver | CD8T |
Last Gift | PID030 | Liver | Myeloid |
Last Gift | PID030 | Liver | Bcell |
Last Gift | PID030 | Spleen | CD4T |
Last Gift | PID030 | Spleen | CD8T |
Last Gift | PID030 | Spleen | Myeloid |
Last Gift | PID030 | Spleen | Bcell |
Last Gift | PID031 | Gut | CD4T |
Last Gift | PID031 | Gut | CD8T |
Last Gift | PID031 | Gut | Myeloid |
Last Gift | PID031 | Gut | Bcell |
Last Gift | PID031 | Kidney | CD4T |
Last Gift | PID031 | Kidney | CD8T |
Last Gift | PID031 | Kidney | Myeloid |
Last Gift | PID031 | Liver | CD4T |
Last Gift | PID031 | Liver | CD8T |
Last Gift | PID031 | Liver | Myeloid |
Last Gift | PID031 | LN | CD4T |
Last Gift | PID031 | LN | CD8T |
Last Gift | PID031 | LN | Myeloid |
Last Gift | PID031 | Lung | CD4T |
Last Gift | PID031 | Lung | CD8T |
Last Gift | PID031 | Lung | Myeloid |
Last Gift | PID031 | Lung | Bcell |
Last Gift | PID031 | Spleen | CD4T |
Last Gift | PID031 | Spleen | CD8T |
Last Gift | PID031 | Spleen | Myeloid |
Last Gift | PID033 | Gut | CD4T |
Last Gift | PID033 | Gut | CD8T |
Last Gift | PID033 | Gut | Myeloid |
Last Gift | PID033 | Gut | Bcell |
Last Gift | PID033 | Heart | CD4T |
Last Gift | PID033 | Heart | CD8T |
Last Gift | PID033 | Heart | Myeloid |
Last Gift | PID033 | Kidney | CD4T |
Last Gift | PID033 | Kidney | CD8T |
Last Gift | PID033 | Kidney | Myeloid |
Last Gift | PID033 | Kidney | Bcell |
Last Gift | PID033 | Liver | CD4T |
Last Gift | PID033 | Liver | CD8T |
Last Gift | PID033 | Liver | Myeloid |
Last Gift | PID033 | Lung | CD4T |
Last Gift | PID033 | Lung | CD8T |
Last Gift | PID033 | Lung | Myeloid |
Last Gift | PID033 | Lung | Bcell |
Last Gift | PID033 | Repro | CD4T |
Last Gift | PID033 | Repro | CD8T |
Last Gift | PID033 | Repro | Myeloid |
Last Gift | PID033 | Repro | Bcell |
Last Gift | PID033 | Spleen | CD4T |
Last Gift | PID033 | Spleen | CD8T |
Last Gift | PID033 | Spleen | Myeloid |
Last Gift | PID033 | Spleen | Bcell |
Last Gift | PID034 | Gut | CD4T |
Last Gift | PID034 | Gut | CD8T |
Last Gift | PID034 | Gut | Myeloid |
Last Gift | PID034 | Gut | Bcell |
Last Gift | PID034 | Heart | CD4T |
Last Gift | PID034 | Heart | CD8T |
Last Gift | PID034 | Heart | Myeloid |
Last Gift | PID034 | Heart | Bcell |
Last Gift | PID034 | Kidney | CD4T |
Last Gift | PID034 | Kidney | CD8T |
Last Gift | PID034 | Kidney | Myeloid |
Last Gift | PID034 | Kidney | Bcell |
Last Gift | PID034 | Liver | CD4T |
Last Gift | PID034 | Liver | CD8T |
Last Gift | PID034 | Liver | Myeloid |
Last Gift | PID034 | Liver | Bcell |
Last Gift | PID034 | LN | CD4T |
Last Gift | PID034 | LN | CD8T |
Last Gift | PID034 | LN | Myeloid |
Last Gift | PID034 | LN | Bcell |
Last Gift | PID034 | Repro | CD4T |
Last Gift | PID034 | Repro | CD8T |
Last Gift | PID034 | Repro | Myeloid |
Last Gift | PID034 | Repro | Bcell |
Last Gift | PID034 | Spleen | CD4T |
Last Gift | PID034 | Spleen | CD8T |
Last Gift | PID034 | Spleen | Myeloid |
Last Gift | PID034 | Spleen | Bcell |
D0 | PID91 | PBMCs | CD4Tm |
D0 | PID91 | PBMCs | CD4Tn |
D0 | PID91 | PBMCs | CD8Tm |
D0 | PID91 | PBMCs | CD8Tn |
D0 | PID91 | PBMCs | Myeloid |
D0 | PID91 | PBMCs | Bcell |
D0 | PID92 | PBMCs | CD4Tm |
D0 | PID92 | PBMCs | CD4Tn |
D0 | PID92 | PBMCs | CD8Tm |
D0 | PID92 | PBMCs | CD8Tn |
D0 | PID92 | PBMCs | Myeloid |
D0 | PID92 | PBMCs | Bcell |
D0 | PID93 | PBMCs | CD4Tm |
D0 | PID93 | PBMCs | CD4Tn |
D0 | PID93 | PBMCs | CD8Tm |
D0 | PID93 | PBMCs | CD8Tn |
D0 | PID93 | PBMCs | Myeloid |
D0 | PID93 | PBMCs | Bcell |
D0 | PID94 | PBMCs | CD4Tm |
D0 | PID94 | PBMCs | CD4Tn |
D0 | PID94 | PBMCs | CD8Tm |
D0 | PID94 | PBMCs | CD8Tn |
D0 | PID94 | PBMCs | Myeloid |
D0 | PID94 | PBMCs | Bcell |
HIVneg | PID91 | PBMCs | CD4T |
HIVpos | PID91 | PBMCs | CD4T |
HIVneg | PID91 | PBMCs | Myeloid |
HIVpos | PID91 | PBMCs | Myeloid |
HIVneg | PID92 | PBMCs | CD4T |
HIVpos | PID92 | PBMCs | CD4T |
HIVneg | PID92 | PBMCs | Myeloid |
HIVpos | PID92 | PBMCs | Myeloid |
HIVneg | PID93 | PBMCs | CD4T |
HIVpos | PID93 | PBMCs | CD4T |
HIVneg | PID93 | PBMCs | Myeloid |
HIVpos | PID93 | PBMCs | Myeloid |
HIVneg | PID94 | PBMCs | CD4T |
HIVpos | PID94 | PBMCs | CD4T |
HIVneg | PID94 | PBMCs | Myeloid |
HIVpos | PID94 | PBMCs | Myeloid |
Unfused | PID43482 | PBMCs | CD4Tm |
Fused | PID43482 | PBMCs | CD4Tm |
Unfused | PID43482 | PBMCs | Myeloid |
Fused | PID43482 | PBMCs | Myeloid |
Unfused | PID44750 | PBMCs | CD4Tm |
Fused | PID44750 | PBMCs | CD4Tm |
Unfused | PID44750 | PBMCs | Myeloid |
Fused | PID44750 | PBMCs | Myeloid |
Unfused | PID44890 | PBMCs | CD4Tm |
Fused | PID44890 | PBMCs | CD4Tm |
Unfused | PID44890 | PBMCs | Myeloid |
Fused | PID44890 | PBMCs | Myeloid |
Unfused | PID47000 | PBMCs | CD4Tm |
Fused | PID47000 | PBMCs | CD4Tm |
Unfused | PID47000 | PBMCs | Myeloid |
Fused | PID47000 | PBMCs | Myeloid |
cGAMP | PID24 | PBMCs | CD4Tm |
Mock | PID24 | PBMCs | CD4Tm |
cGAMP | PID24 | PBMCs | Myeloid |
Mock | PID24 | PBMCs | Myeloid |
cGAMP | PID25 | PBMCs | CD4Tm |
Mock | PID25 | PBMCs | CD4Tm |
cGAMP | PID25 | PBMCs | Myeloid |
Mock | PID25 | PBMCs | Myeloid |
cGAMP | PID27 | PBMCs | CD4Tm |
Mock | PID27 | PBMCs | CD4Tm |
cGAMP | PID27 | PBMCs | Myeloid |
Mock | PID27 | PBMCs | Myeloid |