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Accuracy of intraocular lens calculation formulas in cataract patients with steep corneal curvature

Citation

Pazo, Emmanuel et al. (2020), Accuracy of intraocular lens calculation formulas in cataract patients with steep corneal curvature, Dryad, Dataset, https://doi.org/10.5061/dryad.z8w9ghx9c

Abstract

Objective:To compare the accuracy of five kinds of intraocular lens calculation formulas (SRK/T,Haigis,Hoffer Q,Holladay and Barrett Universal Ⅱ) in cataract patients with steep curvature cornea ≥ 46.0 diopters. 

MethodsThis is a retrospective study of cataract phacoemulsification combined with intraocular lens implantation in patients with steep curvature cornea (corneal curvature ≥ 46D). The refractive prediction errors of IOL power calculation formulas (SRK/T, Haigis, Holladay, Hoffer Q, and Barrett Universal II) using User Group for Laser Interference Biometry (ULIB) constants were evaluated and compared. Objective refraction results were assessed at one month postoperatively. According to axial length (AL), all patients were divided into three groups: short AL group (<22mm), normal AL group (>22 to ≤24.5mm) and long AL group (>24.5mm). Calculate the refractive error and absolute refractive error (AE) between the actual postoperative refractive power and the predicted postoperative refractive power. The covariance analysis was used for the comparison of five formulas in each group. The correlation between the absolute refractive error and AL from every formula were analyzed by Pearson correlation test, respectively.

Result:Total 112 eyes of 83 cataract patients with steep curvature cornea were collected. The anterior chamber depth (ACD) was a covariate in the short AL group in the covariance analysis of absolute refractive error (P<0.001). The SRK/T and Holladay formula had the lowest mean absolute error (MAE) (0.47D), there were statistically significant differences in MAE between the five formulas for short AL group (P=0.024). The anterior chamber depth had no significant correlation in the five calculation formulas in the normal AL group and long AL group (P=0.521, P=0.609 respectively). In the normal AL group, there was no significant difference in MAE between the five calculation formulas (P=0.609). In the long AL group, Barrett Universal II formula had the lowest MAE (0.35), and there were statistically significant differences in MAE between the five formulas (P=0.012). Over the entire AL range, the Barrett Universal II formula had the lowest MAE and the highest percentage of eyes within ± 0.50 D, ± 1.00 D, and ± 1.50 D (69.6%, 93.8%, and 98.2% respectively).

Conclusion:Compared to SRK/T,Haigis,Hoffer Q,and Holladay,  Barrett Universal Ⅱ formula is more accurate in predicting the IOL power in the cataract patients with steep curvature cornea ≥ 46.0 diopters.

Methods

This dataset was a retrospective data collected from the central hospital registral of cataract patients with steep curvature cornea ≥ 46.0 diopters and had undergone intraocular lens implantation. This dataset consists of 112 eyes. The data set has been anonymised and has not been processed. 

Usage Notes

Variable name Variable description
ID Patient ID code
Age Age (year)
sex Sex
F Female
M Male
Actual postoperative spherical equivalent (D) Actual postoperative spherical equivalent (Diopter)
AL (mm) Axial length of the eye  (millimeter)
K1 (D) Flat keratometry (Diopter)
K2 (D) Steep keratometry (Diopter)
SE (D) Spherical equivalent (Diopter)
ACD(mm) Anterior chamber depth (millimeter)
Predicted postoperative SE of SRK/T (D) Predicted postoperative spherical equivalent of SRK/theoretical (Diopter)
Predicted postoperative SE of Haigis (D) Predicted postoperative spherical equivalent of Haigis (Diopter)
Predicted postoperative SE of HofferQ (D) Predicted postoperative spherical equivalent of HofferQ (Diopter)
Predicted postoperative SE of Holladay (D) Predicted postoperative spherical equivalent of Holladay (Diopter)
Predicted postoperative SE of Barrett (D) Predicted postoperative spherical equivalent of Barrett (Diopter)