READ ME Written by Tomas Mikal Eagan 27 february 2022, Bergen, Norway The datafiles are available as a Stata 17 MP file (.dta) and thus with attached values and value labels, preferable to use if you have access to Stata And also as a tab-delimited txt file, where labels were exported, not values for most variables (useful for use in for instance R) Variables in the dataset sex - Women & Men age_cat2 - Age in three categories [in the published paper, we sometimes used age as a continuous variable, then in whole years. That information is not included here in order to maintain full anonymity for participants in the study per current GDPR] bodycomp - body composition was assessed with bioelectrical impedance measurements using a Bodystat 1500 to calculate fat mass index (FMI) and fat free mass index (FFMI). Cachexia was defined as having a FFMI < 14 kg/m2 in women and < 17 kg/m2 in men which corresponds to the lower 95% CI in a normal population (19). Similarly, obesity was defined as FMI > 13.5 kg/m2 in women and > 9.3 kg/m2 in men. smok_habits - defined as never, ex, or current (daily) packyrs_10 - Pack years smoked (defined for ex and daily only) where 20 cigarettes/day for one year equals one pack year divided by ten for regression purposes [where a coefficient then equals increased risk (OR) per 10 pack years smoked]. diabetes - self-reported, and assessed with aid of medical journal by a physician l (knowing for instance all medications used) statin - self-reported, and assessed with aid of medical journal by a physician l (knowing for instance all medications used) ARB_ACE_all - use of either AII blockers or angiotensin receptor blockers sign_CACS - having a calcium score > 100 = "yes", else is "no" cor_stenosis - having significant stenosis on CT angiography assessed by one of two experienced cardiology radiologists. Confirmed coronary stenosis was defined as presence of stenosis (lumen reduction > 50%) COPD_control - either COPD patient or control without lung disease gold - In COPD patients either GOLD stage I/II or stage III/IV copd_exacerb_cat - having had a moderate or serious COPD exacerbation the last 12 months or not. Serious = hospitalization, moderate = treatment with systemic antiobiotics and/or steroids resp_failure - Having arterial blood gass oxygen tension (pO2) < 8 kPa = yes eosinophilic_COPD - Having blood eosinophilia defined as ≥0.3*10^9 cells/L = yes wholelung950 - % lung area of density < 950 Hounsfield units crp_cat - C-reactive protein below 5 or 5 and above