ReadMe for Compliance with mandatory reporting of clinical trial results on ClinicalTrials.gov: cross sectional study, Prayle, Andrew P, Hurley, Matthew N, Smyth, Alan R 2011-12-12 This readme file describes the data files and supplementary files accompanying the above publication. For any further queries please contact andrew.prayle@nottingham.ac.uk The following files are included: 1) "clinicaltrials.gov_search.txt" This is the output from the original clinicaltrials.gov search conducted in Jan 2011. An explanation of the variables is included in the supplementary file "2011-10-31 Prayle Hurley Smyth Supplementary file 3 variables in the dataset". 2) "identify completed trials.r" This is the R script which when run on "clinicaltrials.gov_search.txt" will produce a .csv file which lists all the completed trials. It follows the flow diagram in the paper up until the point where trials are manually cross referenced against the Drugs@FDA database. Proxy settings for R may require setting. Additionally, you may not want to add a line to slow the webscrape down, as some websites block repeated requests for information. 3) "FDA_table_with_sens.csv" This is the final dataset after cross referencing the trials. An explanation of the variables is included in the supplementary file "2011-10-31 Prayle Hurley Smyth Supplementary file 3 variables in the dataset". 4) "analysis_after_FDA_categorization_and_sens.r" This R script reproduces the analysis from the paper, including the tables and statistical tests. The comments should make it self explanatory. 5) "2011-11-02 prayle hurley smyth supplementary file 1 STROBE checklist.rtf" This is a STROBE checklist for the study 6) "2011-10-31 Prayle Hurley Smyth Supplementary file 2 examples of categorization.rtf" This is a supplemntary file which illustrates some of the decisions which had to be made when categorizing trials. 7) "2011-10-31 Prayle Hurlay Smyth Supplementary file 3 variables in the dataset.rtf" This file lists and describes the sources of all the variables used in the final analysis.