Filenames are of the form "..glm": conditioned_variants is either none (unconditional analysis), both (3:135926622_G_T and 3:135848036_C_CA), or the rsid of the variant being conditioned on: rs645040 PCCB 3:135926622_G_T rs61791721 PCCB 3:135804550_T_A rs1247764225 PCCB 3:135848036_C_CA rs687339 PCCB 3:135932359_C_T Analysis was run in plink and imputed variants with MAF > 1% are included in the sumstats. Clinical traits: CAD - UK Biobank defined MI cases (field 42000) Cholesterol - Clinical cholesterol (processed as in Sinnott-Armstrong, Tanigawa et al 2021) hard - "Hard" MI following Inouye et al 2018 hardNoSR - "Hard" MI excluding self-reported MI/CABG/triple bypass/PTCA following Inouye et al 2018 (self-report not used as criterion for diagnosis; cases with both self-report and other evidence are considered cases) HDL_cholesterol - Clinical HDL cholesterol (processed as in Sinnott-Armstrong, Tanigawa et al 2021) LDL_direct - Clinical LDL cholesterol (processed as in Sinnott-Armstrong, Tanigawa et al 2021) SHBG - Clinical SHBG (processed as in Sinnott-Armstrong, Tanigawa et al 2021) soft - "Soft" MI following Inouye et al 2018 plus angina softNoSR - "Soft" MI excluding self-reported angina and MI/CABG/triple bypass/PTCA following Inouye et al 2018 (self-report not used as criterion for diagnosis; cases with both self-report and other evidence are considered cases) Testosterone - Clinical testosterone (processed as in Sinnott-Armstrong, Tanigawa et al 2021) Triglycerides - Clinical triglycerides (processed as in Sinnott-Armstrong, Tanigawa et al 2021) Urea - Clinical urea (processed as in Sinnott-Armstrong, Tanigawa et al 2021) Metabolite measurements: Acetoacetate Acetone Ala bOHbutyrate Citrate Gln Glucose Gly His Ile Lactate Leu Phe Pyruvate Tyr Val HDL_C - HDL cholesterol LDL_C - LDL cholesterol Total_FA - Total fatty acids Total_FC - Total free cholesterol Total_TG - Total Triglycerides CAD - UK Biobank defined MI cases (field 42000) in just Nightingale-assayed individuals