Data files for: A custom-made AAV1 variant (AAV1-T593K) enables efficient transduction of Japanese quail neurons in vitro and in vivo. Data set 1: # Title – fig2_qnpatch_up This excel file contains patch clamp data recorded from cultures quail neurons after 7DIV. Gap free recording protocol was used to assess spontaneous activity in the culture. For assessing intrinsic excitability, cells were current clamped by injected currents to -60 mV. Then current steps were at 50 pA increments and the number of action potentials was calculated. This dataset is linked to Figure2. Sheet#1 – Action potential threshold, Amplitude and half width values obtained from 12 different neurons in vitro. Average and SEM are provided. Sheet#2 – Resting membrane potential was recorded via current clamp recording. Values are listed for 17 different neurons. Sheet#3 – Assessing intrinsic excitability by current clamp (cells were clamped to -60mV). Current steps were at 50pA. In each current step action potentials number were calculated. The table contains the number of action potential at every step for each neuron recorded (total-12). Average and SEM are provided. Data set 2: # Title – fig6_data This excel file contains data linked to Figure6 panel b. Cultured quail neurons were infected either with AAV1* or AAV1wt. Cell number sheet - four different plates for each virus were imaged, and number of infected cells per field was calculated via imagej for each virus. Fluorescence intensity sheet – for the same imaged fields in Data4 the fluorescence intensity was calculated via ZEN software (pixel by pixel intensity calculation for each image). Data set 3: # Title – fig7_data This excel file contains data linked to Figure7 panel b. In vivo assessment of infection efficacy of AAV1* versus AAV1wt. Brain slices of five different quails were imaged via Confocal900 for each virus. Expression level sheet - Fluorescence intensity was calculated for each slice with infected cells (eYFP positive) and averaged to obtain the final intensity for every animal. Cell density - Number of cells per mm squared (density of cells for each slice) was calculated for each slice with infected cells (eYFP positive) and averaged to obtain the final number representing every animal. Imaging fields size was kept constant for all obtained images.