Raw data behind the main results presented in the article "Fight evolution with evolution: plasmid-dependent phages with a wide host range prevent the spread of antibiotic resistances" (Ojala et al. 2013). The data is provided in the form of an SPSS data file (.sav). Contents of the columns (from left to right) are described below: A. km_and_rif_resistant_bacteria_cfu_per_ml - Density (cfu/ml) of bacteria resistant to both kanamycin and rifampicin B. total_number_of_bacteria_cfu_per_ml - Total density (cfu/ml) of bacteria C. km_resistant_bacteria_cfu_per_ml - Density (cfu/ml) of bacteria resistant to kanamycin D. rif_resistant_bacteria_cfu_per_ml - Density (cfu/ml) of bacteria resistant to rifampicin E. treatment - All the experimental treatments <-- different combinations of bacteria, phages and antibiotics - Values in the column correspond to: "1" = E. coli HMS174 + E. coli JE2571(RP4) "2" = E. coli HMS174 + E. coli JE2571(RP4) + PRD1 "3" = E. coli HMS174 + E. coli JE2571(RP4) + Kanamycin + Rifampicin "4" = E. coli HMS174 + E. coli JE2571(RP4) + Kanamycin + Rifampicin + PRD1 "5" = E. coli HMS174 + E. coli JE2571(RP4) + Kanamycin "6" = E. coli HMS174 + E. coli JE2571(RP4) + Kanamycin + PRD1 "7" = E. coli HMS174 + E. coli JE2571(RP4) + Rifampicin "8" = E. coli HMS174 + E. coli JE2571(RP4) + Rifampicin + PRD1 F. experimental_day - Experimental days I-III - Values in the column correspond to: "1" = Day I "2" = Day II "3" = Day III G. frequency_of_km_and_rif_resistant_bacteria - Frequency of kanamycin and rifampicin bacteria <-- Density of kanamycin and rifampicin resistant bacteria divided by the total bacterial density H. arcsin_transformed_frequency_of_km_and_rif_resistant_bacteria - Frequency of kanamycin and rifampicin resistant bacteria after arcsine transformation <-- The transformation was done in order to be able to compare the frequencies between treatments using 1-way ANOVA For any questions contact: ville.p.ojala@jyu.fi