The files are images, which can be loaded into a 3D reconstruction or visualization software like Imaris (Bitplane) or AMIRA (Thermofischer) The files are loaded into the software as raw data following the data import guide for the respective software. ------------------------------------------------------------------------------------------------------------------------------------------------ The files were originally imported in AMIRA as follow: 1. Open Amira application. 2. Select OPEN DATA and choose your files. 3. Image stack overview window will open (DICOM Loader). Press OK. 4. Images are stacked and you are ready to perform analysis or reconstructions.