>Alvinella_pompejana MSDRKAVIKNADMSEEMQQDAVDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSGLNTQLRQFQTTATQRDIDQAAKYIGAGAATV GVAGSGAGIGSVFGSLVIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLILFAFX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMDQVM QFIEPARQFAKDSIRLVKRCTKPDRREFQKIAMATAIGFAIMGFIGFFVKLIHIPINNII VMATATSKKRKFVADGVFKAELNEFFTRELAEDGYSGVEVRVTPARTEIIILATRTQNVL GEKGRRIRELTSVVQKRFNFQEGTVELYAEKVATRGLCAIAQAESLRYKLIGGLAVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGEPCNEYVDTAVRHVLLRQ GVLGIKVKIMLPWDPSGKIGPKRPLPDNISIVEPKDEIPPAQPYSEHKGTKMSKRGRGGS SGGKFRIALALPVGAVINCADNTGAKNLYIIAVQGIKGRLNRLPAAASGDMVVATVKKGK PELRKKVIPAVVIRQRKPIRRKNGVVIYFEDNAGVIVNNKGEIKGSAINGPVAKECADLW PRIASNASSIRKGRVQKVSL-PQVADGENLFGVAHIYASFNDTFIHVTDLSGKETIVRVT GGMKVKADRDEASPYAAMLAAQDVAERCKSLGINALHIKLRATGGNKTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRLMGKPHGLRTARKMRDHRRDQRWHDKD YKKSHLGTRWKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP RDGCLNYIEENDEVLIAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKEKKERPRSDVG ATIRTRKFMTNRLLSRRQMVVDVLHPGRATVPKTEIREKLARMYKTTSDVIFCFGFRTQF GGGKTTGFALIYDNLDYAKKFEPKYRLARHGARKQRKERKNRQKKVRGTKKAKVGQMPRI PLVYNKTYATPRRPFEKERLDQELKLIGEYGLRNKREVWRVKYTLAKIRKAARELLTLDE KDPRRLFEGNALLRRLVRTGVLDESKMKLDYVLGLRLEDFLERRLQTQVFKLGLAKSIHH ARVLIRQRHIRVRKQVVNIPSYIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNMRKGAGGA ADMGSAFAKLFSSLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIGEARDELLRMLSEDELRD AVLLVFANKQDLPNAMNAAEITDKLGLHSLRQRQWYIQATCATSGDGLYEGLDWLSNQLK NQKMPLARDLLNPSPEEEKRKSKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRRKQH---------------NAEKRGKRQVLIRPCSKV IVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVCIRDMEKWTTNL LPSRQFGYIVLTTSGGIMDHEEARRKHLGGKILGFFFMGRMHAPGKGISQSALPYRRSVP TWLKLTPDDVKEQIYKLAKKGLTPSQIEIVWWDSHGVAQVRFVTGNKILRILKAKGLAPD LPEDLYYLIKKAVAIRKHLERNRKDRDAKFRLILVESRIHRLARYYKTKRVLPPNWKYES STASALVAVAEIPEIKLFGKWSSDDVQVSDISLTDYIAVKEKYAKYVPHSAGRYQVKRFR KSQCPIVERLACSLMMHGRNNGKKLMAIRIVKHAFEIIHLLTGENPLQVVVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREAAFRNIKTIAECLADELINAAK GSSNSYAIKKKDELERVAKSNRMTEQMTLRGTLQGHGGWVTQIATTPQFPDIILSASRDK SLILWQLTRESRYGFPRKALRGHGHFVSDVVMSSDGQFALSGSWDGTLRLWDLGTGQTTR RFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIEDGHTEWVSCVRFSPNT QNPIIVSCGWDKLVKVWNLTNCKLKTNHFGHSGYLNCVTVSPDGSLCASGGKDGQAMLWD LNEGKHLYTLDGGDVINSLCFSPNRYWLCAASGPSIKIWDLEGKVVVDELRPEVISTSAE PPQCISLAWSADGQTLFAGYTDNLIRVWQVSMAA-MREYKLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKVVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKLARSWNCVFLETSAKSK INVNEIFYDLVRQINRKNPDPMGDDNK-NNEHINLKVTGQDGSVVHFKIKKNTPLRKLMN AYCDRTGVKSGAMRFRFDGQPINETDTPTQLDMEDGDVIDVFQQQTGGXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXMSDAEGDDVPSA-RGGGGMDINAAIQEVLKTSLIHDGLARGLHEC AKALDKRQAHLCILANNCDEPMYVKLVEALCAEHGINLIKVDDNKKLGEWAGLCKIDKEG KARKVVGCSCVVVKDYGKESMAVDVINDYFKSRKMAAIRKKLVIVGDGACGKTCLLIVFS KDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSI DSPDSLENIPEKWTPEVKHFCPNVPIILVGNKRDLRNDENTKRELMKMKQEPVRPEEGRA MAEKISAYSYLECSAKTKDGVREVFETATRAALQTKKKKKGKMDDFQSGEETAFVVDEVS NIIKESIEGAIGGNAYQHNKVNQWTSNVVEQCLNQLTKLGKPFKYIVTCVIMQKNGAGLH TASSCFWDNTTDGSCTVRWENKTMYCIVSVFGLAILFSERAKIIKPRGREPDEFETSISQ ALLELEMNSDLKAQLRELYITAAKEIDVQGKKAIILFVPVPQLKAFQKIQTRLVRELEKK FSGKHVVVIAQRRILPKPTRKSKRKNKQKRPRSRTLTAVHNNILDDLCFPAEIVGKRIRI CLDGSRVIKVHLDKTQQTNVEHKLDTFSAVYKKLTSKEVTFEFREATLGRGGFRGGFGGR GRGRGRGRGRAKE-DKEWMPVTKLGRLVKDMKIKSIEEIYLFSLPIKEYEIIDHFL-PTL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDYNGHVGLGVKCSKEVATAIRGAIILAKLSI VPVRRGYWGNKIGKPHTVPCKVTGKCGSVLVRLIPAPRGTGIVSAPVPKKLLQMSGIDDC YTSARGQTATLGNFAKATYEAIANTYSYLTPDFWKETIFTKSPYQEFTDYLARMSGGIEV LALKEEDVTKFLACGTHLGSNNVDFQMEQYVYKRKPDGVYILNLRKTWEKLLLAARAIAA IENPADVCVISARPYGQRAVLKFASYVGATPVAGRFTPGAFTNQFQAAFREPRLLVVTDP RIDHQPVTEASYVNIPVIAMCNTDSPLKFVDIAIPCNNKSQHSVGLMWWMLAREVLRLRG TISREVPWDVMVDLFFYRDPEEAEKETEAPDWANETFVAPQLQTTEDWSA-DTETWSAPP ATNEWGG---NPFVSSSRRKNRKRHFNAPSHIRRKIMSAPLSKELRQKYNVRSIPIRKDD EVQVVRGHYKGQQVGKVVQVYRKKYVIHIERIQREKANGATVPVGIHPSKVVIVKLKMDK DRKAILDRKARSKMQGKHTEESISSPSSTRVGSTVRQRKTQASGAGAASMWKFYTEDSPG IKVGPVPVLVISLIFIAFVFMLHIWDKYNR---KGKKKSVTNEVVTREYTINIHKRIHGI GFKKRAPRAIKAIRQFAYKQMGTEDVRIETRLNKHIWSKGIRNVPFRVRVRLARKRNEDE DSPHKLYTLVSYVPVTTFKGTQTVNVESSSKNEFLVNGKYRLVRKIGSGSFGDIYLGINV SNGEELAVKLESHKARHPQLLYESKLYKILQGGVGIPHIRWYGEKDYNVLVMDLLGPSLE DLFNFCGRRFTMKTVLMLADQMIGRIEYVHNKNFIHRDVKPDNFLMGIGRHCNKVFLIDF GLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRGS LPWQGLKAATKKQKYEKISEKKMSTPVEFLCKGYPAEFPMYLNYCRGLRFEEAPDYMYLR QLFRILFRTLNHQYDYVFDWTILKQK----MNQEKLKQRIGGKGTARRKKKVIHRTATTD DKKLQSTLKKLAVTNIPGIEEVNMIKDDGQVIHFTNPKVQASLQSNTFAINGQAETKQIT DLLPGILNQLGAESLSNLKKLATDTADIDEDDDDVPELVENFDEASKNEMTRYSLDPENA TKSAKARGSHLRVHFKNTRETAQTIKHMHLRRAVSFLKNVKAHKECVPFRRYNGGVGRCA QAKNWKTTQGRWPQKSAEFLLQLLKNAESNAEFKGLDTDHLVIEHIQVNRAPKMRRRTYR AHGRINPYMSSPCHVEVILAEREQAISKPRKKKVSQKKLKRQKMMFREKKTGPKPELTEE QKQEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIADIDKEGTGVIDFND FLTMMTQKMSEKDSKEEILKAFRLFDDDETGKISFKNLRRVAKELGENLTDEELQEADRD GDGEINEQEFLRIMKKTSLYMGISRDKWHKRRKTGGRMNPIRKKRKFELGRPAANTKLMP KRIHTVRTRGGNKKYRALRLDMGNFSWGSEAITKKTRITDVVYNASSNELVRTKTLVKNC IAVIDASPFRLWYEAHYAMPLIKKKGAKQTEVEDE-MNKRSKKAKAKYIERRKTARIEPA LEDQFATGKLYACVASRPGRCGRCDGYILEGKELEFYMKKIKAKKGK-SLIIPEKFQHIL RVLNTNIDGKRKVPFALTAIKGVGRRYSHIILKKADVDPSKRPGKLDEDEVEKVVTIMSN PRQYKIPDWFLNRQKDIKDGKYSQVLSNVLDSKIREDLERLKKIRAHRGLRHYWGLRVRG QHTKTTGPRGRTVGVSKKKGSGTDSD-EDGVLEPDEMAQAAGIQEELVSKAKQSRSEKKA RKAISKLGLKQVNGVNRVTIRKSKNILFVISRPDVFKSPASDTYIVFGEAKIEDLSQQAT MVAAEKFKADEEVDETGIESKDIELVMSQANVTRGKAVKALKNNNNDIVNAIMMGRVRTK TVKKASRVIIEKYYTRLTLDFHTNKRICEEIAIIPSKKLRNKIAGFVTHLMKRIQKGPVR GISIKLQEEERERRDNYVPEISAIEEVDPDTKEMLKLLDMNNIP-VQVTQPMAQTMKWEY KEEHPFEKRRAEGEKIRKKYPDRVPVIVEKAQKARVGDLVEKKYLVPSDLTVGQFYFLIR KRIRLRPEDALFFFVNNVIPPTSATMGALYQEHHEEDFFLYIAYSDESVYGMRELRILKL CLNICVGESGDRLTRAAKVLEQLTGQQPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAE EILERGLKVREYELRKNNFSNTGNFGFGIQEHIDLGIKYDPSIGIYGMDFYIVLGRAGFN IAYRRRKNSRIGASHRVQKEEAMKWFQQKYDGVILPGK---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------KLFYTSNIPIILQSALVSNLYVISQMLATKFSGNFFINLLG VWADVGGGGPARSYPIGGLCYYLSPPETLSHVVEDPIHAVLYIVFMLGSCAFFSKTWIDV SGSSAKDVAKQLKDQQMVMRGHRDKSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIG SGTGILLAVTIIYQYFEIFVKEQSEMGGVSTLLFQTERAFQKQPGVFLNKKKVLLPRYVK NIGLGFKTPREAYDGTYIDKKCPFTGRISIRGRILTGVVMKMKMQRTIVIRRDYLHYVRK YNRFEKRHKNVSVHCSPCFRDIAVGDIVTVGECRPLSKTVRFNVVKVNKSSKSKKGFNKF XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRVIRSQRKGAGS VFKAHTKHRKGPARLRAFDFSERHGYIKGVIRDIIHDPGRGAPLAHVVFRDPYRYKLKHE FFIACEGMYTGQFVYCGKKATLQIGNILPVGVMPEGTVVCSLEEKTGDRGRLAKCSGNYA TIISHNPETKRTRVKLPSGTKKVIPSTNRACIGVVAGGGRIDKPMLKAGRAYHKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGKASTVRRDTSAGRKVGLIAARRTGRLRGTKQVTG KXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRRPARCYRYCKNKPYPKSRFCRGVPDP KIRIYDLGRKKARVDEFPLCVHLVSDELEQISSEALEAGRICANKYMVKNCGKDAFHLRV RVHPFHVLRINKMLSCAGADRLQTGMRGAFGKPQGTVARVRIGQALMSVRCKDQHQEKAV EALRRAKFKYPGRQKIYISRKWGFTKWDREDYEKMRLDGRLVPDGVNAKYVPPHGPLEAW MKAQRVTKILGRTGSQGQCTQVRVEFLDDTNRSIIRNVKGPVREGDILTLLESEREARRL RMTKGTSSFGKRNDKTHTLCRRCGRKSYHIQKKRCAGCGYPAKRKRRFNWSEKAKRRNTT GTGRMRYLKIVHRRFLNGFKEG---------MQDRSVAKELDQWIEQLMECKQLTENQVK TLCEQAKEILAKESNVQEVKCPVTVCGDVHGQFHDLMELFHIGGKSPDTNYLFMGDYVDR GYYSVESVTLLVTLKIRFKERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDNQIFCLHGGLSPSIDSLDHIKALDRIQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHTNNLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRC GNQAAIMELDDALKYSFLQFDPAPRRGEPHVTRRTPDYFLMGAYKYMQELYRKKQSDTMR FLLRIRCWQYRQLSKIHRAPRPSRPDKARRLGYKAKQGFVIYRVRIRRGGRKRPVPKGQV YGKPSNCGINQLKNQRSLQAIAEERVGRKCKALRVLNSYWVAQDSTYKFFEVIAIDPFHK AIRRDPTLQWICKPTAKHREMRGLTSANRKSRGLGKGHRFTKTIGGSRRAAWKRNNTLQA HRRRGIALGRLGEERKAWRKDHPFGFVARPTKNADGTMNLMNWECAIPGKKGTPWESGLY KLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSLLDEEKDWRPAVTIKQILLGIQE LLNEPNIKDPAQAEAYTIYCQNRAEYERRVREQAIRFRDPSLGKSSKMLQHINYRMRCTL QDGRTFVGTFKAFDKHMNLILGDCDEFRKVKPKAGKGREEKRPLGLVLLRGENLVSMTVE GPPPADDSLSRVPLPG-GVGPGMGRAAGRGMSGGYGLQGPVHGVGGPGQQHMQPGRAMMQ GPPPADIPTFKLVLVGDGGVGKTTFVKRHLTGEFEKKYIATLGVEVHPLVFHTNRGPIRF NVWDTAGQEKFGGLRDGYYIQGQCAIIMFDVTARITYKNVPNWHRDLVRVCENIPIVLCG NKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLTGDPNLEFVAMPA LAPPEIEMDPSMAAKYEQELQIAQHTALPDEDDDLNAGIKQYYVSKVEELELIVTEKTQN LRRLEAQRNELNAKVRMLREELQLLQEQGSYVGEVVKAMDKKKVLVKVHPEGKFVVDLDK NIDITDVTPNSRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYENVGGLDKQIKEI KEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ KFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRLESGSGGDSEVQRTMLELLNQLD GFEPKQNIKVIMATNRIDILDSALLRPGRIDRKIEFPAPNEEARLDILKIHSRKMNLTRG INVRKIAEMMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFELAVAKVMQKDSEKNMSI KKLWKLGFVENFGLSGAAAVISKTAAAPIERVKLLVQNQDEMIKAGRLDRPYKGVIDCTV RTFKSEGILPFWRGNLANCIRYFPTQALNFAFKDKVKAAFKMNKTDSYAVKFSKNV---- ------------------------------------------------------------ ----------------------------------------------PMNTVRRRMMMTSG EAVKYKGSWDCAIKVIKQEGFMSLMKGAGANILRGVAGAGVLAGFDKFKELYMTWRSMTD MSSLDRQIENLRRCEIIKESEVKALCAKVREILVEESNVQRVDSPVTVCGDIHGQFYDLR ELFKVGGDVPDTNYLFLGDFVDRGFYSVETFLLMLALKVRYPDRITLIRGNHESRQITQV YGFYDECLRKYGSITVWRYCIEVFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRAIDRK QEVPHDGPMCDLLWSDPEETQGWGVSPRGAGYLFGSDVVQQFNTSNDISLICRAHQLVME GYKWHFNETVLTVWSAPNYCYRCGNVAAIFELDEHLKQDFKIFEAAPQEQRGKPQANYFL LKLPPEVNRILYVKNLPYKITAEEMYDIFGKYGAIRQIRVGNTADTKGTAFVVYEDIFDA KNACDHLSGFNVCNRYLVVLYYQPHKAYKKMDLQKKAEELEKLKAQHGLSTPDIKMSIGV PIKVLHEAEGHIVTLETNTGETYRGKLLEAEDNMNCQMSDITCTYRDGRTAQLENVFIRG SKIRFLILPDMLKNAPMFKKVGAGRGKSAILRAAARGRGRGTGGRGAGRMQNDSGECVDM YIPRKCSASTRIIGAKDHASIQINLAEVDETTGRMTGQYKTYAICGQIRRMGESDDCITR LAKKDGLVAK-VRGPRKHLKRLHAPKHWMLDKLGGVFAPRPSTGPHKMRECLPLVVFLRN RLKYALTYDEVKKIVNQRLIKVDGKVRTDKTYPAGFMDVITIEKTAENFRLIYDVKGRFT IHRITSQEAKYKLCKVKKIIIGLKGVPHLVTHDARTIRYPDPMIKVNDTVQVMGTKDDEY DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTA GQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADQNIVIMLVGNKSDL RHLRAVPTDEAKAFAEKNNLSFTETSAIDSTNVETAFQQILTEIYKIVSQKQLKDSPDDN NVQTIVVQPTDPSADRGKKACCMSSRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVR GKDLVVLGVEKKAVAKLQEDRTVRKIALLDDHVALAFAGLTADARILINRARVECQSHKL TVEDPVTLEYITRYIAQLKQRYTQSNGRRPFGLSTLIIGFDGTPRLYQTDPSGTYHEWKA NAIGRSAKTVREYLEKHYSADLVSEHETIKLALKALMEVVQSGSKNMEVAIMKRGELLKT LESEELDKYIQEIEKEKEEEAEKKKQK--------------------------------- ----------------------------------------NQERLKPQXEKQEEERSKVD DLRGTPMSVGSLEEIIDDHHAIVSTSVGSEHYVNILSFVDKDQLEPGCSVLLNHKVHAVV GVLSDDTDPMVTVMKLEKAPQETYADIGGLDQQIQEIKESVELPLTHPEYYEEMGIKPPK GVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPA IIFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPA LIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTLAEDVNLEDYIMAKDDLSGADIKAICT EAGLLALRERRMKVTNEDFKKAKENVLYRKNEGTPEGLYL-RYEYSPFQSSNKVEYVLAR VDDLVNWGRKSSLWPMTFGLACCAVEMMHFAAPRYDMDRFGVVFRASPRQADCIIVAGTV TNKMAPALRKVYDQMPDPRWVISMGSCANGGGYYHYSYSVVRGCDRIIPVDIYVPGCPPS AEALLYGVLQLQKKIKRWNSMQMWYRRTDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYA NNSNYKNDTIIRKEAYVHKSVMDELKRIIEESEIMQEDDNLWPPPDRVGRQELEIVIGDE HISFTTSKIGSLVDVKGSKDPEGLRTFYYLVQDLKCLVFSLIGLHFKIKPIMVATKKSKK AIESINSRLALVMKSGKYVLGYKQTLKTLRQGKAKLVIIANNTPPLRKSEIEYYAMLAKT GVHHYNGNNIELGTACGKYFRVTTLSITDPGDSDIIRSMPAGMTEYKLVVVGAGGVGKSA LTIQLIQNHFVEEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGF LCVFAVNNNRSFEDINQYREQIKRVKDADEVPMVLVGNKVDLPTRSVETKQGKLLSDSYG IPYVETSAKTRQGVDDAFYTLVREIRKYMGDRYNIHSQLEHLQSKYIGTGHADTNKWEWL TNQHRDSFASYIGHFDLVNFFAVAENEAKARVRFNLMEKMLQPCGAPPERPEDMKIELCV FSGYKIYPGHGKKLVKVDGRGFQFVNGKCEKSYLMKRNPRKINWTVLYRRKHKKGQTEEV SKKRTRRTTKFQRAITGATLTDILAKRNQKPEVRKAQREQAIRAAKEKQKAKEGSKPRMG GKRMKLNISYPATGCQKLIEVDDEHKLRHFYEKRMAAELPADRLGDEWKGYIVRISGGND KQGFPMKQGVLTSGRVKLLLSKGHSCFRPRRSGERRRKSVRGCIVDANLSVLNLVIVRKG VNDIPGLTDKTIPRRLGPKRASKIRKLFNLSKEDDVRQYVVRRPLPPKTKAPKIQRLVTP LVLQRKRHRLALKKRRAAKRAEEAAEYTKLLAQRVKEAKERKAERRRTASKSRKVKAKDL RGKKKDELQRQLNELKHELAQLRVSKVTGGSASKLSKIVVVRKSIARVMTVMHQTQKENL RKFYKPKDLRRKKTRAMRKALTKHELSLKTAKQRRKSRAFPLRKYALK------------ ------------------------------------------------------QGGDFS NKDGTGGESIYFEDETFELKHDKPGLLSMANAGPNTNSSQFFITTVPTPHLDGKHVVFGK VKKGMDVVRCLEEQKTGNDQPLKECVIYDCGEL---------------KRVKLELKYTVD CSHPVEDGILDCSAFEKFLQERIKVAGKTNNFKSKITVVSEIPFSKRYLKYLTKKYLKKH NLRDWLRVVANSKDSYELRYFQINNEEEEDDEDNXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----LAEVKKHNTSKDLWFAIHDKVYDVT KFIEEHPGGEEVLLEQGGGFATEAFEDVGHSTDARELMKTYEIGELVEADRNVLMSWLVP LAIAVGAALVYRYLMSYMLQHLHNGWQVDQAILSEEDRVVIIRFGHDWDPTCMVMDETLY RIAEKVKNFAVVYLVDISKVPDFNKMYELYDPCTVMFFYRNKHIMIDLGTGNNNKINWAM EDEQEFIDIVETVFRGARKGRGLVVSPKDYSTKYRYKKLQKQLEFLEVQEEYIKDEQKNL KKEYLHAQEEVKRIQSVPLVIGQFLEAVDQNTGIVGSTTGSNYYVRILSTIDRELLKPSA SVALHKHSNALVDVLPPEADSSITMLQADEKPDVTYADIGGMDIQKQEVREAVELPLTHM ELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVR DVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTVNVKVI MATNRADTLDPALLRPGRLDRKIEFPMPDRRQKRLIFATITNKMNLSEDVDLDDYVARPD KISGADINAICQEAGMQAVRENRYVVLPKDFEKGYKNNIKKDEMEHEFYKSHVPLTIDSV RDRVMLVLKLYDKINPDKLTLESHFMNDLGLDSLDQVEIIMAMEDEFGFEIPDADAERLM RPADIVQYIADKEDLARRVQAMADDLKNVEFETSEEVEVTPTFDGMNLREELLRGIYAYG FEKPSAIQQRAIRPIIKGRDVIAQAQSGTGKTATFAISILQCLDTTVRETQALVLSPTRE LAVQIQKVVLALGDYMNVQCHACIGGTSVGEDIRKLDYGQHVVSGTPGRVFDMIRRRNLR TRSIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLVSATLVHEILEMTSKFMTDPI RILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKM RDANFTVSSMHGDMPQKERDAIMKEFRSGSSRVLISTDVWARGLDVQQVSLVINYDLPNN RELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVGDLI-TMRRP FDPVAHDLDAGFRLTKFAELKGGCKVPQEVLLKLLEGLKTS-ESEQAHFTYVAQAPRIGI GMDSCITPLRHGGLSLVQTTDFFYPLVDDPYMMGKIACSNVLSDLYAMGVTECDNMLMLF TVSQKMTDKERDVVAPLMIRGFKDCAEEAGTSINGGQTVVNPWITIGGVATTVCQPNEFI MPDNAVVGDVLVLTKPLGTQVAVNAYQWLDQPERWNRIKLVVSEDDVRKAYQRAMFSMAR LNRMGAHLMHKYNAHGATDVTGFGLLGHANNLARVQKNEVGFVIHNLPIIAKMAAVSKAC GNMFGLLQGHSAETSGGLLIALPREQAAAFCKDIEKQEGYQAWIIGIVEKGTRTARIIDK PRVIEVPAKEKDLFIAVITRNDAYFIHIDAHAEECFFDKVTSGTKMSLMFEVAEGGFLDI DVKIIGPDDKNIYSGERESNGKYTFAAHMDGVYKYCFSNKMSTMTPKIVMFSMDIGEKPK ASQNKLEEMINELSVSLTGVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMT LGQVYYLKRFFEVRRVV-------YLTAVRHTLTAALCLENFSSQVVERHNKPEVEVRTS KELLLTPVVISRNEKERVLIEGSVNALRISIAIKQADELEKILCHKFMRFMMMRAENFCI LRRKAVEGYDISFLVTNFHTEQMFKHKLVDFIISFMEEIDKEISEMKLAVNSRARISAEE FLKRFSRKKILLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEIMVDDRLV TMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTVPNTFKTLDSWRDEFLIQAGPRDPEH FPFVVIGNKIDLENRAVSTKRAQQWCQSKGDIPYFETSAKEAINVEQAFQTVAKNALAQE TEVELYNEFPDQIRLTNEQNESSCGCTFPFDARFPNQNQTRACWQNYVDYHRCQKIEDYG PCNYFKKIFTSMCPNAWIEKWDEQMEQGIFAGKV-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------LFEMART KKACIIFFDEIDAVGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDT LDPALTRPGRLDRKVEFGLPDLEGRALIFKIHARSMSVEKDIRYELLARLCPNSTGAEIR SVCTEAGMFAIRARRKMATEKDFLEAINKVIKAYAKFSSTPRYMTYNMGAEKKHINIVVI GHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITI DIALWKFETKNFYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQT REHALLAFTLGVKQLIVGVNKMDSTEPPYSEARYNEIKKEVSAYIKKIGYNPETVAFVPI SGWHGDNMLNMTWFKNWEIYTGVTLIEALDSIDPPSRPTDKPLRLPLQDVYKIGGIGTVP VGRVETGVLKPGMVVTFAPPNITTEVKSVEMHHQALEKAEPGDNVGFNVKNVSVKDIRRG NVCGDSKNDPPKAVESFKAQVIILNHPGQIQAGYAPVVDCHTAHIACKFAELLKKIDRRS GKELEDNPPHVKSGDAAIVNMIPSKPMCCEAFSEYAPLGRFAVRDMKQTVAVGVIKSVVR KEGVSGKVTKAAQKAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSYAYLF KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES FRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARR DVKKEEGEAFAREHGLIFMETSAKTAANVEEAFINTAKEIYQKIQDGVFDINNEANGIKI GPQHSLTNPSSGGGGSQSGGMTRGRIDLGDVTIHNIKQLKRLNQVVFPVAYNDKFYKDVL EVGELAKLAYFNDIVVGAVCCREDRSDGRRRLYIMTLGCLAPYRRLGIGSKMLEHVLKIC EKDGNYDNIYLHVQVNNEDAVKFYEHFGFEIVERNENYYKRIEPADAYVLQKTFR-XXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----ELNVDNLISRLLEVRGCRPG KTVQMSESEVRALCLKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEA NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFN IKLWKTFTDCFNCLPIAAIVDEKIFTCHGGLS---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---MFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEIVGTNVSTC YISCPADSKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPF ICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDEL PAEFKLYLPVQQKMTDNTIQNLQDPFADDEGIHIRIQQRNGRKTLTTVQGISSEFDLKKI VKVAKKEFACNGTVVEHPEYGEVIQLQGDQRQRISQFLKKFGLEEQIKVHGF--VYSFDG LVVFGLLMISTCAYMRRV-PKLFLSERKGFLGVFYKAAVIGTRLHIPVAVTCVMMALYVL IL-------ALARQLPRTTSKRKSLAASFVGCRNICTTAEVSSILEERILGGMSADLEET GRVLSIGDGIARVYGLKNIQAEEMVEFSSGLKGMALNLEPDNVGIVVFGNDKLIKEGDVV KRTGAIVDVPVGMELLGRVVDALGNPIDGKGPLNTASRARVGTKAPGIIPRISVKEPMQS GIKAVDSLVPIGRGQRELIIGDRQTGKTAVAIDTIINQKRFNDGQDEKAKLYCIYVAIGQ KRSTVAQIVKRLIDTDSMRYTIVVSATASDAAPLQYLAPYSGCAMGEYFRDNGKHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDDFGGGSLTALPVIE TDA--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ MEAIFRLPYKVLLCPNIKLKKPSWVRQPSAMVMFAVVLTSYFLVTGGVIYDVIVEPPSIG STTDERGNSKPVAFMPYRVNGQYIMEGLASSFLFTLGGLGFVILDQTNKPTTPRLNRILL LSVGFLSILISFFMCRVFMRMKLPMPKVRRSRKPPPEGWELIEPTLDELDQKMREAETET HEGKRKVESLWPIFRIHHQKSRYIYELFYKRKAISRELYEYCLKENIADKNLIAKWKKQG YENLCCLRCIQTRDTNFGANCVCRVPKPKLQEGKIVECVNCGCRGCSGEYAQVLKMLGNG RLEAMCFDGTKRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYTADEARNLKV YGELPESAKINEDEECNVCFDDIDEI---FLMKLSHETVTIELKNGTQVHGTITGVDVSM NTHLKSVKMTVKNKDPVQLESLSIRGNNIRYFILPDSLPLDNLLIDDTPRAKARK-TSQK PKTEMTPEELAAREQEEFNTGPLSVLTQSVKNNTQVLINCRNNKKLIGRVKAFDRHCNMV LEEVKEMWTEVPKTGKGKKKSKPVNKDRYISKMFLRGDSVILVLRNPLPIIIDARGHLLG RLAAVVAKNILQGQRIVVVRCEGINISGSFYRNKLKYLAFLRKRMNTNPSRGPFHFRAPS KIFWRTVRGMLPHKLTRGKVALSHLKVFEGIPPPYDKKKRMVVPSALRVLRLKARRKYCV LGRLSHEVGWKYQNVIETLESKRKVKSSQYYK---------------------------- GNAEKGKKIFVTRCAQCHTVEAGGKHKTGPNLHGFIGRKTGQAPGYTFTDANLNKGIVWN RETLDIYLENPKKYIPGTKMIFAGLKKKAEREDLIAYLEEATKIFVERTLAILKPDVLAE EIEDIILRSGFSIFRKRRVQLTPEQASDFYAEHFGKLFFPSLVAYMSSGPIIPLVLARDK AISYWRELIGPTNALKARETHPDCLRAIYGTDDQRNGLHGSDSYSSAEREIRFFFPDSIV EPIPIGQAARDYLAKTVNPTLMKGLTELCKKKPEDPVIWLADWLLSNNPNKPKVKMFEAR LVQGSLLKKVLEAIKDLLNEATWDCNSTGMSLQAMDSSHVSLVSLQLRADGFDTYRCDRN LSLGINLSSMAKIMRCASNDDAITIKAGDDADTVTYMFESPNGEKVSDYEMKLMDLDTEH LGIPETDYSCVVKMPSAEFQRICRDLSQIGESVTICCTKEGIKFSASGDLGTGNIKLAQT ANVDKEEEAVVIEMQEAVTLTFALRYLNFFTKATPLSAQVSLSISADVPLVVEYKIGDVG YIRYYLAPKIEDGDDARCSATYQTSSSPVKGKIVAVIGAVVDVQFDEGLPAILNALQVTD RKPKLILEVAQHLGENTVRTIAMDGTEGLVRGQECVDTGASIRIPVVPETLGRIMNVIGE PIDERGPIESNAFASIHAEAPAFVEMSLEQEILETGIKVIDMLAPYAKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIEGGVISLKDKTSKVSLVYG QMNEPPGARARVALTGLTVAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIA ELGIYPAVDPLDSTSRILDPNVVGEEHYEVARGVQKILQDYKSLQDIIAILGMDELSEDD KLTVARARKIQRFLSQPFQVAEVFTGSAGKLVPLKETIRGFKEILNGTYDHLPEVAFYMV GGIEEVVQKADRLAEERMLMPKKNRVAIYELLFKEGVMVAKKDYYAPKHPELDVPNLQVI KAMQSLKSRGLVNEQFAWRHYYWYLTNEGIQYLRDFLHLPPEIVPATLKRQQVPEDRAAY RRAAGPDKKADVGAGT-MGKQNSKLKPEVLEDLRQHTEFTDEEIQEWYKGFLKDCPSGHL SVEEFKKIYGNFFPYGDASKFAEHVFRTFDTNSDGTIDFREFICALSVTSRGKLEQKLKW AFSMYDLDGNGYISRQEMLEIVSAIYKMVGTVMKMPEDESTPEKRTDKIFRQMDKNLDGK LSLEEFIEGARSDPSIVRLLQCDPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX MTNTKGYRRGTRDLFSRPFRRKGVIPLSTYMKVYKVGDIVDIKGNGAVQKGMPHKYYHGK TGRVYNVTQHAVGVIVNKRVGGRIIAKRINLRIEHVKHSKCRQEFLNRVKENERKKAEAK ERVCCKRMPAQPRPGYIVRARKQKPELLQPIPYEFIAANRATFKQVHPEEGELNWKDMTD RAANTTFLIELTKGLGIVMSKLFTEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAICPAQAITIEAETRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEY STETHEELIYNKEKLLENGDKWEPEIAANLQADFLYR-----KVPKSDPKNNHETDKEQQ EAIEKIDEVQNEIDKLNEQASEEILKVEQKYNKLRQPYFAKRSELIAKIPNFWVTAFVNH PQVSALLNEEDEEALQYLTKVDVQEFEDIKSGYKINFHFDDNPYFENKVISKEFHLNSSK ATPINWKEGKDLTKKAKKRGHEEQESFFIWFLDTGDAGADELGEVIKDDIWPNPLQYYLA SEIDEDAD---------KKLTKEEELLLQDFSRNVNTKSSALFYGNAFIVSAIPIWLFWR IHQMEPMFVFGAMTLVSTWLVAFAYKNVKFFLKHKIALKRGEAVSREVMKKVADDKKMSK QEKEERILWKKNEVADYEATTFSIFYNNALFLMLVIITSFYVLRSFSPTVNYIMSIGSAG GLLALFSTST---QNKACQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQT VCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNSDTFSRAKSWVKELQRQ ASPNIVIALSGNKADLRMVEYEEAXAYA-------------------------------- ----------MAEYLASIFGTEKDKVNCSFYFKIGACRHGERCSRLHNKPTFSQTVLLQS LYINPQNKAQITMSDVEAQEHFDDFFEEVFSELEDKYGEIEEMNVCDNLGDHLVGNVYVK FRYEEDAEKAVADLNNRWFNSRPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKP ISRELRRELYGRSRRSRSRSRDRRRSRSRER----HRSRSR----MFLTRSEYDRGVNTF SPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVVLAVEKRVTSPLIEPNSIEKILEVDSHIA CAMSGLIADSRTLIDRARVEAQNHWFTYNEKMSIESVTQAVSNLALQFGDDDAGPGAMSR PFGVALLFAGIDEKGPRLFHMDPSGTFLQYDAKAIGSGSEGAQQALQEVYHKSMTLKEAC KESLKILKQIMEEKLNETNVEMATVTPDKLFQMASKEEIEEYIKDIAQKTWEMSNNVETI SSMDDIYRYDKKQQQDMLTTKPWEKDPHFFKNIKISALALLKMVMHARSGGNLEVMGLLL GKVEGNTMIVMDCFALPVEGTETRVNAQAQAYEYMAAYTESAKQVKRLENAIGWYHSHPG YGCWLSGIDVGTQMTNQQFQEPFVAIVIDPVRTISAGKVNLGAFRTYPKGYKPPDEGPSE YQSIPLNEI-----------------------------------VNTLSSSSLLTNSDYT TGQIIDLSDKLEQSEAQLGRGGFMEKKSEDKLAKATKDGCKNTIEAIHGLMSQVLKDKLF NQVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDVENELLDYEE-DEQETKEVKGTYVSIHSS GFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILSMDVVCQAKSGMGKTAVFVLATLQ QLEPVDGQVSVLVLCHTRELAFQISKEYERFSKYMNGIKIAVFFGGMPIKKDEQTLKTNC PHIVVGTPGRILALAKALNLKHLXHFILDEC----------------------------- ------------------PMEVYVDDDSKLTLHGLQQHYVKLKDNEKNRKLFELLDALEF NQVIIFVKSVPRCMALCQLLVEQNFPAIAIHRAMSQEDRLSRYQQFKDFQKRILVATNLF GR--------------------------------------------------PPSYADLG KSARDLFSKGFNYGFYKIEAKTKTANGVEFTSTGSSNHDTAKFSGSLESKYKWSEYGLTF TEKWNTDNTLATEITIEDQLLKGLKLSFDTQFAPQTGKKSGKIKTGYKQEYFNANCDVDF DFAGPTINGAAVVGYSGWLAGYQFSFDKSKLSRSNFAVGYSTDDFTLHTSVNDGTEFNGS LFQRVSKELETGVQLKWAAGSNATSFGIAAKYCPDXDSTYRAKVN--SQIGLSYQQKIRD GISVTLSTSIEGKNFNQGGHKVGLGIDFEAQSVREKALQDYRKKLLEHKELEARLKEMRE QQKELNKQYDKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQIDKSK LRQGTRVALDMTTLTIMRYLPREVDPLVYNMSTEDPGSVSYSEIGGLSEQIRELREVIEL PLLNPELFQRVGITPPKGCLLFGPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIGES ARLIREMFGYARDHQPCIIFMDEIDAIRRFSEGTSADREIQRTLMELLNQMDGFDALGQV KMIMATNRPDTLDPALLRPGRLDRKIEISLPNEQARLEILKIHANPIAKHGEIDWEAIVK LSDDFNGADLRNVCTEAGMFAIRAERDYVIEEDFMKAVRKIADNKKLESKLDYKPVMPES LSTVVARFYNEYVSSTPTRLKLLDVYLVYIILTGIIQFLYCCIAGTFPFNSFLSGFISCV GSFVLAVCLRVQVNPQNKTEFGNISPERAFADFVFAHIILHLVIMNFIGSLASPSQLLPL ELVDKCIGSKIHIIMKSDKEIVGTLLGFDDFVNMVLEDVVEFENTPEGRRVTKLDQILLN GNNITMLVPGSEGPEVIDHYENPRNVGTLDKNDKSVGTGLVGAPACGDVMKLQIKVDENG KIVDAKFKTFGCGSAIASSSLATTWIKGKTLDEASTIKNQDIAKELCLPPVKLHCSMLAE DAIKAALQDYKIKNQMLVLVLGDMHIPHRTSQMPSKFKRLLVPGKIQHILCTGNLCTKES FDYLKTLASDVHVVRGDFDENMNYPEQKVVTVGQFRIGLCHGHQVVPWGDTESLAMLQRQ LDVDILITGHTHKFEAFEHENRFYINPGSATGAFNPLDMNVIPSFVLLDIQQSTVVAYVY QLVGDEVKVERIEYKKMGKFMKSGKVVLVLSGRYAGRKAVIVKNYDDGTTDKPYGHALVA GIDRYPRIVTKKMGKKKIKQRSKIKAFVKVYNFNHLMPTRYSVVNLEKSIINKDAFRDPA LRRKARREAKMKFEERYKTGKNKWFFQKLRFERSFIMVKPDGVHRGIVGEIIKRFEQKGF KLVAMKFMWATEEHLKKHYADLAGKPFFPKLIKYMSSGPVVPMVWEGNVVKTGRKMLGET NPFDSLPGTIRGDFCIEVGRNICHGSDSVESADKEINLWFSKDELITWTPCDEDWVYE-- VPKPLKTPAKAKEKALKARKSVRLGVHEKRRKKIRTSVHFHRPKTLRLPRQPKYPRKSTP RRPRLDKYKIVKYPLTTESAMKKIEDNNTLVFIVDKRANKPQIKIAVKQLYDIDVSKVNT LIRPDGEKKAYVRLAPDFDALDVASKIGIIMASKQRMRVANDKHSKNVLNRGNVPKTLKQ TEEKTPVGPWLLGLFVFVVCGSAVFQIIQSIRM-----WTAVATWRWVANDENCGICRMP FDGCCPDCKMPGDDCPLVWGQCTHCYHIHCIVKWLNSQPDRQLCPMCRREWKYK-MIRFI LIQNRAGKTRLAKWYMHFDDEEKQKLIEEVHAVVTIRDAKHTNFVEFRNFKIVYRRYAGL YFCICVDITDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYSIVDEMFLAGEIRE TSQTRVLKQLLMLSSLEQPTVFSKIIDKTIPADILYEDDLCLAFNDISPKAPIHFLVIPK KLIPRLQSDEQLLGHLLLVAKKVATKESGYRLVINNGRDGAQSVFHLHLHVFGGRQMGWP PMGGLISYFANLFGSKERRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVQYKN LKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSMDRDRIGISKQELVSMLEEEELKKAT LCVFANKQDIEGALTVTEVANALGLSSIKNRKYQIFKTSAIKGEGLDEAMEWLANALQNT K-----------KCFIEEIPDETMVVGKYRVELFDRQQNAFVPTRAGLGMHVEVRDPDDG VVVSRTYAAEGRFTFTSHSAGEHVICLHSNSSAWFGGGQLRVHLDIQVGEHANDYQQIAA KDKLTELQLRVRQLLDQVEQITKEQNYQRYREERFRQTSESTNQRVLWWSIGQTIILLLT GFWQMKHLKSFFEAKKLVMFYHVSLEHEILLHPKYFGPNLLDIVKQKLFTEVEGTCTGKY GFVVAVTIIDDIGAGLIQPSRGFVVYPVKYKAIVFRPFKGEVLEAVVTQVNKVGIFTEIG PLSCFISRHSIPPDMEFDPNSNPPCYKTKDEDTVIQQDDEIKLKIVGTRVDATDIFAIGT LLDDYLGL--RLYVRAVFTGFKRGLRNQHENTALLKIEGVNRRKETEFYLGKRCAYVYKA KK----------------------------------------------------MAKKTY DLLFKLLLIGDSGVGKTCLLFRFSDDAFNSTFISTIGIDFKIKTVELDGKKIKLQIWDTA GQERFHTITTSYYRGAMGIMLVYDITNAKTFENISKWLRNIDEHANEDVEKMILGNKCDM EDKRQVPTSKGEQIANEHGIPFLETSAKSNINVEKAFMDLAQAILNKMPQNEHIERWRKL HGYRLDYHERKRKKEGRLPHEQAKKAKKLRGIKAKLYNKKRHAEKVQMKKTIKMHEERKT KQKSNDDVPDGAVPAYLLDREGQNRAKVLSNMIKQKRKEKAGKWEVPLPKVRGISEKEMF KVVKTGKSKRKGWKRMVTKVTYVGEGFTRKPPKYERFIRPMALRFKKAHVTHPELKATFC LPIIGVKKNPTSPLYTSLGVITKGTVIEVNISELGLVTQGGKVIWGKYAQVTNNPENDGC INAVLLVMASRPLITVYNEKGQATKVAITLPAVFRSPIRPDIVTFVHSEMRKNSRQPYAV SSKAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRR INVNQRRYALTSAIAATGIPALVMSKGHRIEQTPEVPLVIADSIEEIKKTKQAVGVLRRF KAWSDIEKVKNSRRFRAGKGKMRNRRRIQRRGPLIIYNQDNGITRAFRNIPGVTLLNVSR LNLLKIAPGGHVGRFCIWTESAFKKLDSIYGTWTKKSKAKSNYMLPVPKMTNSDLSRLLR AEEIRKTLRRRFQRQQKRKQKKNPLKRLEYMVKLNPYAAAQKKMARHKQERQKLLDAKRG LA---------------GSGEQELATKTLQIQSKRFYLDVKQNRRGRFIKIAEVGAGGKK SRLLLAMSTAAEFRDHLSDFSDHYASLGPPNPDSLPEDGKLKSEVMVKDNRRYYLDLKEN QRGRFLRVTPRSQQRSQIAIPAQGMIEFRDALTDLLDEFGTDDHEGQGDLPEARSMRVEN KMFYFDVGQNRRGVFMRVSESNFRTAITIPERSWAKFRDILTEFVEKXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXMNIRNARPDDLMNMQHCNLLCLPENYQMKYYFYHG LSWPQLSYVAEDIKGNIVGYVLAKMEEDPEDSVPHGHITSLAVKRSHRRLGLAQKLMDQA SRAMVECFGAKYVSLHVRKSNRAALHLYKNTLKFDIYEIEPKYYADGEDAYAMRRNLSEF IEKYMSHTILLVQPGKRPEARTYSDYESVNECLEGVCKIYEEYLKRTNPNSPSITYDISQ LFDFIDQMADLSCLVYEKTSGKYVPHNKDWIKEKIYILLRKQAGKMAEEPVEKKTEETKR VVHTYPLIRHSDMNEEMRTEAMELCVTACEKFSNNNENAAKMIKETMDKKFGASWHAVVG EGFGFEITHEVKNILYMFFGSTYGIVVWKCSMSHRKFSAPRHGSLGFLPKKRSSRHRGKV KAFPKDDKNKPLHLTAFLGYKAGMTHIVRDVDRPGSKVNKKEVVEPVTIIETPPMIIVGV VGYIETPHGLRTFRTLFAEHLSDECKRRFYKNWYKCKKKAFTKACKKYQDELGKKEIQKD LNKMKKYCTVIRVIAHTQMKMLKKRQKKAHIMEIQINGGTIADKVDWAYAHFEKPVQVSD VFAQDEMIDIIGVTKGKGFKGVTSRWHPKKLPRKTHKGLRKVACIGAWHPARVAFSVARA GQKGYHHRTEMNKKIYRIGQGIHMKDGKLVKNNASTESDVTEKTITPMGGFPHYGEVNND FIMIKGCCVGPKKRVLTLRKSLLVHTKRRALEKITLKFIDTSSKFGHGRFQTHQEKRTFM GPLKKDMQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLG LWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWFPEVSHHCPNTPIILVG TKLDLREDKETVEKLKEKKLSPITYPQGLAMAKEIGAVKYLECSALTQKGLKNVFDEAIR AVLCPKPKQQKKNKCLILMFDSSLKKKKKKKMPFDVDSVLDDIVLDDSLSKKKKKKKKPF DLSELEEVLPKKEESLPSKKKKQDTDRDYTYDELLKRVFDIMREKNPDMVAGEKKRFVMK PPQVMRVGTKKSSFSNFSEICKMLHRQPKHLLQFLLAELGTSGSIDGNNQLIIKGRFQQK QIESVLRRYIKEYVTCHTCRSPETILQKDTRLYFLQCETCGSRCSVASIKSGFQAVTGKR AAIRAKTT---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------RVQWSPHNETILASSGTDRRLHVWDLSKIGEEQSAEDA EDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEEPDTPAS ELEMPTSSTARVYADVNTHRPREYWDYEAHTVEWGQQDDYQVVRKLGRGKYSEVFEAINI TNNEKCVIKILKPVKKKKIKREIKILENLRGGTNVIALLAIVKDPVSRTPALIFEHVNNT DFKQLYQTLTDYDIRYYMFELLKALDFCHSMGIMHRDVKPHNVMIDHETRSLRLIDWGLA EFYHPGQDYNVRVASRYFKGPK-------------------------------------- ------------------------------------------------------------ -------------------------------KVPETLLKKRKARRTKQHDKRQLIFRRAE KYVKEYRMRERDEIRMKRLARKHGNFYVAPEAKVAFVIRIRGINGLHPRPRKVLKLFRLL QINNGTFVRLNKATLHMLRIADPYVTWGYPNLKSVRELIYKRGYGRIGGRRIPLTDNELI ERSLRRYGIICIEDLIHEIYTCGPHFKEANRFLWTFKLNTPTGGWVKKNNHFVDGGDFGN REDKINALLRRMMQFMLLFSRQGKLRLQKWYIAHPDKLKKKITRELITMILARKPKMCSF LEWKDLKIVYKRYASLYFCCCVEASDNELLTLEIIHRYVELLDKYFGSVCELDIIFNFEK AYFMLDELLIGGEVQETSKKNVLKAIAAQDLLQEETPQGFFEDHGLGXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-VDEA TKRTLAKIPLLKTKAGPRDGELWVQRLKEEYQSLIKYVQNNKESDNDWFRLESNKEGTRW FGKCWYIHELLKYEFEVEFDIPVTYPVTAPEIALPELDGKTAKMYRGGKICMTDHFKPLW ARNVPKFGIAHAMALGLGPWLAVEIPDLISKDIIKHKE------FFSELRRMNKRQLYYQ FLNFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFYRGDLLFLTNYEEEPVRVGE IVVFKVEGRDIPIVHRVLKVHEKENGSVKFLTKGDNNQVDDRGLYAPGQLWLSKSDIVGR ARGYVPYVGIVTILMNDYPKFKYAILALLGMFVLIHRE----NPEYDYLFKLLLIGDSGV GKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYR GAHGIIVVYDVTDXESXHNVKAW------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------EEARARIMQIHSRKMNVSPDVNYEELA RCTDDFNGAQCKAVCVEAGMIALRRGATELTHEDYMDAILEVNAKKKANLNYYA------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------FERLVDIICDKMSESLDSDPTQ TKRLTENPNPQNAGCQC-------VSRDYISQPRITYKTVSGVNGPLVILDDVKFPKYAE IVNLTLQDGSRRAGQVLEVSGSKAVVQVFEGTSGIDAKHTTCEFTGDILKIPVSEDMLGR IFNGSGKPVDKGPAVLAEDFLDIQGQPINPWSRIYPEEMIQTGISAIDGMNSIARGQKIP IFSAAGLPHNEIAAQICRQAGLVKGPTKGVLDGHEQNFAIVFAAMGVNMEIARFFKQDFE ENGSMENVCLFLNLANDPTIERIITPRIALTAAEFLAYQCEKHVLVILTDMSSYAEALRE VSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLT GYITEGQIYVDRQLHNRQVYPPINVLPSLSRLMKSAIGEGMTRDDHADVSNQLYACYAIG KDVQAMKAVVGEEXLTPDDLLYIEFLQK-------------------------------- -------------------QGPGFIGIKFCQECNNMLYPKEDKENTRLLYACRNCGYQEE ADNPCIYVNKIQHDVDELTQIIGDVIADPTLPRTEDHPCPRCGHKEAVFFQSQSRRADEG MRLYYVCTEPHCMNRWTEKPPYKVADISLADWGRKAIEIAENEMPGLMMMRKIYGPKKPL KGARIAGCLHMTVQTAVLIETLKELGAEVRWSSCNIFSTQDHAAAAIAKTGVPVYAWKGE TDEEYLWCIEQTLIFSDGQPLNMIVDDGGDLTNLVHDKYPQYLPGIKGLSEETTTGVGNL YKRLAKGTLKVPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGKVVVVAGYGDV GKGCCQALRAFGARVIVTEIDPINALQAAMEGYEVARLEDALDEARLYVTTTGCKQIITG EHFNKMLEDSIVCNIGHFDCEIDVKWLNENCVSKDTIKPQVDRYTLKNGRHIILLAQGRL VNLGCAMGHPSFVMSNSFTNQVLAQIELWTKS---------------------HLEHLGV RLTKLTDEQAEYLGVPKEGPFKPNHYRYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXMSTSNVENLPPHVIRHVARELAELQKEPPEGVKVFPNDDDITDIQAAIEGPSG TPYAGGYFKIKLVLGKNFPREPPKGFFITKIFHPNVAKNGEICVNTLKRDWKTDYGLKHI LLTIKCLLIVPNAESALNEEAGKLLLEQYDDYSMR-----EIHAKPMFQNILQTVKNSPF SSPFGLKINPTRSIAAAAEGESCEYGSAKFFALCGFGGILSCGITHTAVVPLDLVKCRMQ VDPGKYGNIIKGFQVTLKESGIRELGKGWAPTFFGYSMQGLGKFGFYEIFKIVYSGMLGE ENAYLWRTSLYLAASASAEFFADIALCPMEAVKVRIQTQPGWANTLREGVPKLMAEEGLW GFYKGIVPLWGRQIPYTMMKFACFERTVEALYKYVVPKPRSECSKGEQLIVTFVAGYIAG VFCAIVSHPADTIVSKLNQQKGSTFFEIGKNLGFYGMWKGLFPRIIMIGTLTALQWFIYD SVKVYFRMPRPPPPEMPESLKRKLEHWRNERIVAVALLPLIPTALAYLLDMTLSVMVLHS HWRLTGVCQDYIHFSIAAFGSLCYFNYTDIGFAKAVRLIYSQLNEQCDEDASELIFPKEF ENADTLLISEVQRKQKNESKEEEQELSEVFMKTLNYTSRFSKFKNRETIAAVRGLLIQQK LHKFEFAAIANLCPETADEAKALIPSLEGRFEDEELQQILDDIQTKRSFQYDRQPHLAKQ DIENLNIEELTPLSPQVISRQATINIGTIGHVAHGKSTLVKAISGVQTVRFKNELERNIT IKLGYANAKIYKCDDPNVPRPQCYTSRGSNHPDVFPCDISGSGKFKLVRHVSFVDCPGHD ILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILIMQNKIDLVKESQ AKDQYDQILKFVQGTVAEGAPVVPISAQLKYNIDAVCEYIVKKIPIPKRDFMSEPRLIVI RSFDVNKPGCEVDALKGGVAGGSLLRGVLKVGQEIEVRPGIVSKDHEGVLKCQPIKSRIV SLFAEQNDLQYAVPGGLIGVGTKIDPTLCRADRMVGQVIG-VGTLPDIFIELEINYYLLR RLLGVRTEGDRKGAKVQKLTKGEILMVNIGSLSSGGRVLAVKADLAKIGLTNPVCTEVGE KIALSRKVEKHWRLIGWGQIRRGVTVKPMAELLLDSNIRLWVFLPIVIITFLVGIIRHYA TILLMSDKKVERQQMSDSQALIRSKILRENGRFIPKESFLTRKDFFNNEHTGFFIKNPMT DPSMMTDMMKGNMTNVLPMIIIGGWINWAFSGFLTTKVPFPLTLRFKPMLQRGVELSSLD ASWVSSASWYFLNVFGLRSMYSLILGQDNAADQTRMMQDQMTGMATGMPQDTSKAFRAEW EALEICEHQWALEGVEEEIMMFLWDWFAGILNFLGLYKKSGKLVFLGLDNAGKTTLLHML KDDRMAQHVPTLHPTSEELTMGGMKFTTFDLGGHAQARRVWKDYFPAVDGIVFLIDVFDR ERFTEARSELESLLRDEQIMQAPVLILGNKIDLPGAASEDEIRTVFNLHGQTTGKGTVSR SELRPMELFMCSVLKRQGYGEGFRWLAQYINVLRRNRPGTKTENWSNWPDESFEEMDSTL AVQQYIQQAIRRDFSSIEEILTPPEGQDEGVWKYEHLRQFCLELNDLAVKLQSECNPETC TQMTATEQWIFLCAAHKTPKECPAIDYTRHTLDGAACLLNSNKYFPSRVSIKESSVAKLG SVCRRVYRIFSHAYFHHRVLFDEYEAETALCKRFTLFVTKYNLMSKDNLIVPILED-MPN IKLQSSDGEVFEVDVEIAKQSVTIKTMLEDEEDEEEPVPLPNVNAAILKKVIQWCSYHKD DPPPPEDDENKEKRTDDISSWDAEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMI KGKTPEEIRKTFNIKNDFTPAEEEQVRKENEWCEEKXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------- ------------------------------------------------------------ -----------------------------------------------------FPQTTDS KILQEYITQEGHKLEVAPRPPMAVTNAVSWRSEGIKYRKNEVFLDVIESVNLLVSANGNV LRSEIVGAVKMRVYLSGMPELRLGLNDKVLFESTGRGKSKSVELEDVKFHQCVRLSRFEN DRTISFIPPDGEFELMSYRLNTHVKPLIWVESVIERHAHSRVEYMIKAKSQFKRRSTANN VEIVIPVPTDADSPKFKTTSGSCKYAPDQNAVIWTIKSFPGGKEYLMRAHFGLPSVAGEE TEGKPPIHVRFEIPYFTVSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRTQ------ ----------------------------------LIEPKGGGGGAGEGFDVAKTGDARIG FVGFPSVGKSTLLTNLAGVYSEVAAYEFTTLTTVPGCIKYKGAKIQLLDLPGIIEGAKDG KGRGKQVIAVARTSSLIFIVLDVLKPLQHKKLIEYELEGFGIRLNKKPPNISFRKKDKGG INLTATVAQSELDLDTVKTILGEYRIHNADVTLRIDATAEDLIDVIEGNRVYIPCIYVLN KIDQISIEELDIIYKIPHCVPISAHHKWNFDDLLEKMWEYLNLTRIYTKPKGQLPDYNAP VVLKSGQTTVEDFCNKLHRSIIKEFKHALVWGSSVKHQPQKVGKEHVLQDEDVVQIVKKM AKHHPDLIFCRKQPGVAIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGSYQGRCVIC GGPGVSDAYYCKECTILEKDRDGCPKIVNLGSAKTDLFYERKKYGFKKR----------- --KSGFRKIPVPTNRYSPLKENWMKIFTPVVEHLHLQIRFNLKTRNVEIRTCKETKDIAA LQKAADFVKAFTLGFEVEDALALVRLDDLYLESFEITDVKPLKGDHLARAIGRIAGKGGK TKFTIENVTKTRIVLADSKIHILGSYQNIAIARTAICNLILGSPPSKVYGTMRSVAARSA ERXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------- -------------VLYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWR HYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAVILVFANKQDLPEAMKPHEI QEKLGMTRMRDRNWYVQPSCATTGDGLYEGLTWLTSNAKSFGDLKTDSGLKALNEYLADK SYIEGYQPSQADVAVFEALSEPKADYEHALRWYNHIKSYN-NRNSLPGKKKPVSEYGPAG TGEDDDDDDIDLFGSEAERIKQERLAAYEARKAPAVVAKSNIILEVKPWDDETDMKKMEE LVRSIEVDGLLWGSAKLVPVGYGIKKLVISCVVEDDKVGTDLLEEKITEFEDYVQSVDIA AFNKIQVQEVREVTRIERIGAHSHIRGLGLDDALEARNVSQGMVGQTSARRAAGIILEMI KEGKIAGRAVLLAGQPGTGKTAIAMGMAQALGQGTPFTAIAGSEIFSLEMSKTEALTQAF RKSIGVRIKEETEIIEGEVVEIQIDKPVTGTGAKVGKLTLKTTEMETVYDLGQKMIESLT KEKIHAGDIITIDKATGKITKLGRSFTRARDYDAMGASTKFVQCPEGELQKRKEVVHTVS LHEIDVINSRTQGFLALFSGDTGEIKSEVREQINSKVAEWREEGKAEIVPGVLFIDEVHM LDIECFSFLNRALETDMAPVLIMATNRGITRIRGTNYQSPHGIPIDLLDRLLIVSTSPYE EREIKQILKIRCEEEDVEISDDATTVLTRIGMETSLRYAIQLITTAHLVCRRRKGTEVSV EDIKRVYSLFLDESRSTQFLKEYQQEFMFHE----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------EILMQDWDNALEDLNQLQAVIDSSLETLQQRTWLI HWSLFVFFNHPKGRDLIIDLFLNQPQYLNAIQTMCPHILRYLTTAVITHKQVVKDLVKVI QQESYTYKDPITEFLLCLYVNFDFDSAQQKLKECEIVLENDFFLTACLKEFIENARLFIF ETFCRIHQCISIGLLADKLNMTADEAERWIVNLIRNARLDAKIDSKLGHVVMGTQAISPY QQVMEKTKGLSFRSQMLALTIEKKLGAKQ------------------------------- ------------------------VIKGWDEGVAQMSVGQVAKLTCSPDYAYGAKGYPGV IPPNATLIFEVELLGMEMPKYYCDYCDTYLTHDSPSVRKTHCNGRKHKENVRIYYQKWLE EQVQKLVDETTAAYKAGKIQNNPFAGAGAMIPPPASQTEGPAPPGMPMGGP-MPGPMGP- -PPMGPMPPMMRPVGP-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXVACLLALAAAEPTVHFEERFWEPRWVNSEHKGSEQ GVFKWSAGKFYGDPEKDKGIQTSQDAHFYGISAKFDKPFSNEGKTLVIQFTVKHEQNIDC GGGYVKLFPSDVNQKDLHGETPYLIMFGPDICGPGTKKVHVIFNYKGKNLLTKKEIRCKD DVFTHLYTLIVRPDNTYEVKIDNKKVESGDLESDWDFLPPKKIKDPEAKKPDDWDERETI DDPDDTKPDDWDQPEHIPDPDAKKPDDWDDEMDGEWEPPMIDNPEYKGEWKPKQIPNPAY KGKWVHPMIDNPEYSPDENLYRYTDIGAIGFDLWQVKSGSIFDNILITDDESYAEKIGDE TWGVTKDAEKKMKEEQDEIERKKREEEEAAKKDSEGDEEEED--XXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNVFRLSGDLCHLLAIIILLLKI WKTRSCAGLSGKTQIMFAMVYTTRYLDLFTSFISVYNSTMKVIFIVASYATIYLIYLKFK ATYDSNHDTFRIEFLLVPVAGLAFLINHDFTPLEILWTFSIYLESVAILPQLFMISKTGE AETITSHYLFALGTYRALYIVNWVYRYYYEGFFDIIAVVAGCVQTILYCDFFYLYITKVW KGKKLTLPAMKIEEVKSTTKTQRIATHSHVKGLGLDENGFAHQSAAGLVGQEHAREAAGI IVEMIRCKKMAGRAVLLAGPPGTGKTAIALAIAQELGNKVPFCPMVGSEVYSSEIKKTEV LMENFRRAIGLRIKETKEVYEGEVTELAPVETENPMGGYGKTVSHVIIGLKTAKGTKQLK LDPSIYESIQKEKVEVGDVIYIEANTGAVKRQGRSDTFATEFDLEAEEYVPLPKGDVHKK KEVIQDVTLHDLDVANARPQGGQDIISMMGQLMKPKKTEITDKLRKEINKVVNKYIDQGI AELVPGVLFIDEVHMLDIECFTYLHRALESTIAPIVIFATNRGKCTIKGTEDIVSPHGMP LDLLDRVMIIRTLPYSQEEMQQIIKIRATTESIQISDDSLQILAEIGVKSTLRYAVQLLT PSSLLAKINGVDSIGRSEIEEINELFFDAKSSAKILAEQEDKYMKDFEMDDEGEQSVKKL KQKVKVRKGRGF-TNTGIEEYEAMETAGPGPQRSVEGWILFITNVHEEATEDDIHDLFAE YGDIKNLHLNLDRRTGFLKGYALVEYEMFSEAQAAIEALNGSEVLGQKINVDWCFVRGPA K--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-FLFTSESVGEGHPDKLCDQI SDAVLDAHLKQDPSAKVACECASKTGMIMLLGEISSKAHVDYQKVVRDTIKHIGYDDSSK GFDYKTCNVLSALEEQSPDIAQGVHEGRDEADIGAGDQGLMFGYATDETEEAMPLTVILA HKLNAKIAELRRNGGLPWARPDSKTQVTCEYRMQKGACIPQRVHTVVISLQHSEDITVEH LRKELMEKVVKVVI-ARYLDDKTIYHINPSGRFVIGGPQSDAGLTGRKIIVDTYGGWGAH GGGAFSGKDFSKVDRSAAYATRWVAKSLVKAGLCKRVIVQVSYAIGLAEPLSIFISSYGT GTKSDAELLKIVKANFDLRPGAIVRDLDLKRPIYQKTAAYGHFGREEFTWEHPKELIFMA GSALRRLMAEYKQLTLNPPEGIVAGPLSEENFFEWEALITGPEGTCFEGGVFPARLTFPV DYPLSPPKMKFTCDLFHPNIYPDGRVCISILHAPGDDPMGYESSAERWSPVQSVEKILLS VVSMLAEPNDESAANVDAAKTWRDDRAKFNEIAHRTVRKSLGLMRLEKCYFCSSTIYPGH GIQFVRNDCKLFRFCRAKCHSAFKKKRNPRKVKWTKAFRKSAGKELTVDPSFEFEKRRHV PVKYDRQLWQNTIKAMKRINEIRTKREGLYIMNRLEKGKELRKLADIQEVEKHIHLIRAP GAKMTVYKVVMVRHGESEWNKENKFCGWHDADLSELGVEEAKSAGKMLKEKGYTFDIAFT SVLKRAIKTLYFVQDELDLHWIPVVRHWRLNERMYGALQGLNKAETAAKHGEEQVKIWRR SYDVPPPAVEKSDERWPGHDPKYQYVDRNLIPRSECLKDTVARVLPFWYDAIVPEIKKGQ RVLIAAHGNSLRAMVKYLDNMSDADIMALNIPTGIPLVYEIDEELKPIKHYYLASEEQVK AAMEKVA------MELQDVYYNKSEYIETASGNKVSRQSVLCGSQNIVLNGKTIIMSESI IRGDLANVRIGRHCVVGKRAVIRPPFKKFSKGVAFFPIHIGDHVMIEEDSVINAAQVGSY VHIGKNCIIGRRCILKDCCAIADNTVLPPETVVPPFTLFSGSPG---------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------KEEAHLNTSFKHFIFFVQEFNLV DKRELAPLQDLIDKLT---MGIDISHKHKRKVIRRKPKSHDLYLQLLVKLYRFLARRTGC KFNRIILKRLFMSKTNRAPMSASTLARQMKKPGRQDKIAVCVGTITDDSRAYKFPKLKVC ALRVTRAARARILKAGGELMTFDQLALKSPRGKNTVLLQGPRKAREAYRHFGPAPGVPHS HTKPYVRSKGRKFERARGR--------DLKHGNIHGSYEVATTVDVLLNVISKEKWSNTE ELIDLIRKHGKQLMASQPSENTIDNMVCRVLKIIKDESIVDAINEFLVELETSRQALDHI HSNEVIDTVEAFLRKNFKVIVVEYHGQQLATRLAAVGINTTVITDSAVFAMMARVNKVII GTHTVMANGGLKAVGSHAIALAAKYHSVPLVVCAPMYKLSPQYLCSYDDAFNKFGSPGDI YNPIFDYVPPELVTLFIFNIGGNAPSYVYRLLSEMYDMIIPVRCFTCGKVIGNKWETYLG LLQAEYTEGDALDALGLKRYCCRRMLLSHVDLIEKLLNYAPLEKKSPEAVEGRKHIDVQT ELYLEELSDRVEEADVECQTDAFLDRPPSPLFIPAKSGRDIATQILEGDLFDFDVEVKPI LEVLVGKTVEQSLLEVMEEEELYNLRAQQRAFEELRNSELVEQQRLEEQERRHREEKERR MKQQREILRKEKETADKIAARAFAQSYLADLVPSVFGTLSDNGYFYDPVERDVETGFLPW LMDHVEDQXHRSVLGRTVLDGLI-------------MKARGNLKEYKVIGRMRPTEKTPQ PPLYQMRIFAPDKPTAVSRYWYFSSQLKKMKKTHGEILLCQEIREKRPKKIKNIGIWLRY DSRSGTHNMYKEYRDLSVAGAVTQCYRDMAARHRARAGSIQVIRCEVIPASKCRRPYIKQ FHDSKIKFPLPHRVSRRLHQPQFTTVRPST--SALQEMKNFWKKNQGRPSSPWVIYRPHL PMLTSLTHRMTGIAMGVALYGISVGLFLAPGDFPSYIEFVKSLNLSPLILFPIKSVMAFP LVYHYMNGIRHLTWDAGYGFKLATQYKTGWTILGSMSYWSGSIALSAYRDQHFKGSRQEQ EDLLLRSTTLYVGNLSFFTTEEQIHELFSRAGDVKRIIMGLDKFKKTPCGFCFVEYYTRE DAENAMRYANGTRLDDRVVRTDWDAGFREGRQYGRGKSGGQVRDEYRTDYDSGRGGYGKI IQQKLKPNYTLKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWHAYDGKFEKTISGH KLGISDVAWSTDSKLLVSASDDKTLKIWDVSTGKCLKTLKGHSNYVFCCNFNPQSNLIVS GSFDESVRTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGQKNEKYCVFANFSVTGG KWIVSGSEDNMVYIWNLQTKEIVQKLQGHTDVVL-------------------------- ---MIIYKDLFTEDEMFSDIYPGLLYKVTGKDDALIGANASSGINIVLSTKKSYQSHLKD YMKSLAALQFYCGLAIVEWDIPYMYFFKDGLIPEKVMAVEYNEGVVIAADSRTTTGAYIA NRVTNKLTKITDRIYCCRSGSAADTQAIADVVAYNLGFHKMQMEEEPLVKTAATVFQDMC YNYRDSLSAGIICAGWDHKLGGQVYSIPLGGMCVRQPCTIGGSGSTYIYGYVDSTFKEQM TKEECLKFCANAVALAMSRDGSSGGVIRMASITKDGVERLTILHDDLPKFIMIGIAALLL LLCCCFCICKKCCRRKKAKDLKKGLKGAVDLNSVKLLGNSYKEKVQPDLEELEVNMEDNE DAESTKSEVKLGKLQFSLDYDFQKGELSVGVIQASDLPGMDMSGTSDPYVKVYLLPEKKK KHETKVHRKTLNPVFNETFIFKVPYSEMGSKTLCFAVYDFDRFSKHDQIGQVKVPLNSVD LGRVVEEWRDLTSPESDSEK-NKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSD PYTKIALYMGNKRLKKKKTTIKKRTLNPYYNESFTFEVPFEQIQKVTLIITVVDYDRIGT SEPIGRVVLGCNSSGTELRHWSDMLANPRRPIAQWHTLQEMPEKN--------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------NPDNIVFVMDA SIGQACEVQAAAFKEKVDVASVIITKLDSHAKGGGALSAVTKSPVLFIGTGEHIDDFEPF KVQPFISKLLGMGDIEGLIDKVNELKLDDEELMKKLKH---------------GQFTLRD MYDRFQNIMMSIMSYNGAAIVAMKGKDCVAIASDCRFGIQAQTVSTNFQKIFEMGPHLYL GLPGLATDVQTVAQRLKFRLNLYELRENRRIKPKTFLSMVSNLLYERRFGPYFVEPVIAG LDAKSGEPFIASLDLIGCPMVTEDFVVSGTCTEQLYGMCESLWVPDMQADYLFETISQAL LNAVDRDAVSGWGAVVYIIEKDKVTTRTLKARMDMTSKDYYFDSYAHFGIHEEMLKDEVR TLTYRNAMYHNRHLFKDKIVLDVGCGTAILSMFAAKAGAKKVIGIECSSIVEYAEQIVKA NKLDDVITLVRGKVEEVSLPDGIEKVDIIISEWMGYCLFYESMLMTVLYARDKWLAPGGL IFPDRATLYVCAIEDRQYKDEKINWWDNVYGFDMSCIRKVAIQEPLVDVVNPKQVVTNSC LVKEVDIYTVTE--------FHLQCRRNDYIQALVTYFNIEFTKCHKRTGFSTGPDADYT HWKQTDEYLTVKTGEEIYGTFAVKPNKRNNRDLDFKLEIDFRGELSEMVETLTYKMRMVK EDKATWKSNYFLKLVQLFDEYPKCFIVGVDNVGSKQMQHIRIALRVMMGKNTMMRKAIRG HVETNPALEKLLPHIKGNVGFVFTKCDLSEIRKVISENRVAAPARAGAIAPLDVTLPAHN TGLGPEKTSFFQALAIPTKISRGTIEIQSDVKLIREGEKVGASEATLLNMLKISPFTYGL VIKQVYDSGTIFDPAILDVTDEDLRCRFMEGVANIASVSLAIGYPTAASAPHSIVNGFKN LLALAAVTNITFKEAETMKEAAAKGKLIAVIGDEDTCTGFLLGGIGELDKHRQPNFLVVN KDTSISELEEAFRKFTTRSDIAIVLINQNAAEMIRHEIDSYNKTIPAILEIPSKEFPYDP SKDSILRRAKGMFSADDFRGNEVTLPMELCSNFDTEEIKRLGKRFKKLDLDNSGSLSIDE FMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSLFSVKGDKESKLRFAFKIYDMD KDGYISNGELFQVLKMMVGNNLKDAQLQQIVDKTIIHADTDGDGKISFEEFCAVVGNLDV HKKMVVDVMPHIKAWDDFAKHAEMLYLNDPIKTRFVIKYRHCDGKLTVKVTDNQSCFLYQ TEHAQDVKKLEKLTSLLMRHMASKELFEEVKLCRNNREREHYDNMADLYAVINTLQCLEK AYIKDVVTPKEYTAACSKLLVQYKAAFKQVQGAEFPTVEAFMKKCKLDCPAALERIKEGR PITIKDDKGNTSKCIADIVSLFITIMDKLRLEIRAMDEIHPEMRDLMDTMNRLSILPADY EGKVKVQEWLETLSSMQAADELSDTQVRQLLFDLESAYSEFNRILHNMLSSMLKNHQSRQ YIRKELQEKRKRDATTATALSHALVDHLNSGVAQAYVNQKKLDTETKLLQVNAAQFAKQT TQWLKLVEDFNQALKEIGDVENWSKSIEADMRTISCALEYAY-PSFIVKPIGGEKNGQTR KVRVRRLPRSYPTEVLHKKRRKCFKDHKHKLRRSITPGTILILLAGRHKGKRVIFLKQLK SGLLLVTGPHPINGCPLRRINQIYVIATKTKIDISGINIPERLTDDYFRRKKPRKPKQNE GEIFDTKKEEYKVTEERKEDQCIVDKQILEVIKKHPEKKLLAGYLRNMFGLSNKQYPHKL VFLEWLFGRKKTPQELLRQNQRALNKAMRDLDRERQKMEQQENKIKMDIKKMAKQGQMDA VKIMAKDIVRTRRYIKKFILMRANIQAVSLKIQTLKSNDAMAQAMKGVTKAMATMNKQLK LPQIQKIMMEFEKQSEIMDMKEEMMNDAIDDALGDEDDEEESDALVSQVLDELGLQMADQ LSDLPGTGQSAAKQPVGVSDADADLEARLENLRRQ------------------------- ----------------------------------------KGGRGDQLLFCDDCDRGYHM YCLKPPLSEPPEGSWSCHLCIQEFYGSMDRLITLYPLTNYTFGTKDPLYEKDASVPARFK RMREEFAKDGMRRTVEGVLIVHEHGLPHVLLLQLGTTFFKLPGGELTPGEDQVEGLKRLL TDMLGRQDQAPVNWTIEDVIGNWWRPNFEPPQYPYIPAHITKPKEHKRLFLVQLPDKALF AVPRNYKLVAAPLFELYDNAAGYGPIISSLPQALSRFSFLYN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------YEHLGEEYPEVLG SILGALKSIVNVIGMTKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGAEFVS AREWMRICFELLELLKAH-KAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVC TTVAIXIVAETCSPFTVLPALMNEYRVPELNVQNGVLKSLSFMFEYIGEMSKDYVYAVSP LLEDALMDRDLVHRQTAMSAIGHLALGVYGFGCEDALNHILNYVWPNIFESSPHVVQAFM AAIEGIMVGLGPTKILQYCMQGLFHAARKVRDVYWKVYNTVYIGAQDSLVPAYPRIPDDE KNTYIRYELDYILDDFMCEDEEYDLEYSEDSQSEPDVDLENQYYNSKALKEDDPRTALES FQKVLELEGKDKGEWGFKALKQMIKINFKLNNYDEMMDKYKQLLTYIKTAVTRNYSEKSI NSILDYISTSKNMELLQNFYETTLEALKEAKNDRLWFKTNTKLGKLYFDREEWTKLQRIL KQLHASCQTDEGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPL IMGVIRECGGKMHLREGEYEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGIN PFDSQEAKPYKNDPEILAMTNLVSAYQNNDISEFEKILKANRRNIMEDPFIREHIEDLLR NIRTQVLIKLIKPYTRIHIPFISKELNIDPGEVENLLVSCILDDTIHGRIDQVNQLFELD VGGAKYNAMEKWTQQLSTLHQAIVNKMAVLLMGKSGSGKTSMRSIIFANYIARDTRRLGA TIDVEHSHVRFLGNLVLNLWDCGGQEAFMESYFASQRDNIFRDVEVLIYVFDVESRELEN DMHYYQSCLEAILQNSPDAKIFCLIHKMDLVPDDQRDLIFQQREEDLKQLSKPLATSIWD ETLYRAWSSIVYQLIPNVDKIEMNLNSFARVIDADEVLLFERATFLVISHCNTKPHPDVH RFEKISNIIKQFKLSCSKLAASFHSMEV-------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------WLRHNTPEDSKVMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMAS TEDKAYEIMRELDVNYVLVIFGGLAGYSSDDINKFLWMVRIGGSTDRGQHIKEHDYYTPQ GEFRIDKDGSPTLLNCLMYKMCYYRFGSVYTEAGKPTGYDRVRNTEIGNKDFELDVLEEA YTTEHWLVRIYKVKDLENRG---------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------VQAPADCVSAVYTVLARRRGHVTADAPIPGSP MYIIKAFMPAIDSFGFETDLRIHTQGQAFCLSVFHHWQIVPGDPLDKSIVIRPLEPQPAT HLAREFMIKTRRRKGLSEDVSINKFFDDPMLLELAKQDVMLSYGMQETFNLFDNKGDGKI YAHQVGEVLRAMGQNPTENQVKKCSDPDYRLSFEQFLPMLQTVMRNRDTSTLEDFVEGFR VFDKEQNGTMSSAELRHLLTSLGERLTDEEVSELIAGQEDAHGNINYEEFVKMVMNG--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------FEADRRAFVITINXFGTELTKDDRAKLYPRCGK LHPYGLARLALADDYDQVRAVAEHYAEYRVLFEECGSNQGEKTLEDKFFEYEVMLMKNAF MQQFHFGVFYAFIKLKEQECRNIIWIAECVSQRHIAKIDSYIPIFXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXX-------YYCLTGQGHRFDIGWLLSEVSPYLWANLGIGLAISLS VVGAAWGIYTTGTSILGGGVKAPRIRTKNLVSIIFCEAVAIYGIIMAIVISNNKNYHAGF AMFGAGLTVGFSNLFCGLCVGIVGSGAALADAQNSTLFVKILIVEIFASAIGLFGIIVAI LQTNNAKMGN--AATRRLQKELSDNMEETNILKWNGTLFPKDPPYNKGAFKISIEFPAEY PFKPPKITFKTKIYHPNIDEKGQVCLPIINAENWKPATKTEQVLQALAALVDRPEPEHPL RADLAEEYTKDKKKFMKTAEDHTKKYAEKRPADGASLFYPKQCSALRKNEFVILKGNPCK IVDMSTSKTGKHGHAKVHLVGLDIFTGKKYEDICPSTHSMNVPIVTRTEYQVVDVSNGYV SIMDDNGELREDLKLSATVIKAMNKEQISDIKS--------------------------- ---------------------------------DDCIIVSDTNTHTIHVFNEGRFLRQFG KAGRKKAEMKQPFGVACDGE-YILVVDSGNSRINVFTMNGKFVSMIEMNQPRGMAITHDG YLYVADRDNHCIKKYR--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------QEFMILPTGASSFSEAMKMGTETYHHL KNVIKKRYGQDACNVGDEGGFAPNIQSNEEGLELLTLAIENAGYTGKIQIAMDVAASEFC KKYDLDFKNKDSNPDNWLTSDQLLEVYKGFIAKYPVVSIEDAFDQDDWNAWTKMNHIQLV GDDFLVTNPKRVREAIEKNSCNALLLKVNQIGTVTEAIEACKMSQDAGWGVMVSHRSGET EDTFIADLXCGLCTGENQTGAPCRSERLLLVHQLL--------------------XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXMNAPPTFETFLLYDGEKKVIIERDTKVPNAAIFTVNKEDHTLG NAIRTQLLKDPQVLFAGYKVPHPLESKFVLRIQTTPDYSPQEAFTNAITDLISEISLLEE RFKDAIREKQEGDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXYHS QFQNPSQVLGNMAVFPLRTQFRGPAYDIIDEALHYFKANVFFKNYEIKNEADRTLIYITL YITECLKKLQRCQSKTQALKDMHTLAISRFYLPGEAQFPLNGMFARPSDRQEEDAMRSFF TQLRQETGIRVVEKVFDQNTDKPSKWWMCFAKRQFMQKSLAGPGQSGPYNYSYIFKYIII GDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVCGQKIKLQIWDTARQERFRAVT RSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIFLIGNKCDLEAQRDVTYE EAKQFADENGLMFLECSAKTGENVEEAFLDTARKIYQNIQDGSLDLNAAESGVQHKPSTP RNALSTDQTQNTEGCSCMAIHAVCVLKDSPVTGTIHLKEEG-VTVTGEITGLTPGKHGFH VHEFGDNTNGCTSAGGHFNPHGKEHGAPEDENRHAGDLGNVVAGVINMKDKLVKLTGPDS VIGRTLVVHVDEDDLGRGGHEQSKITGNAGGRLACGVIGITKMVNFTVDEIRAIMDKKKN IRNMSVIAHVDHGKSTLTDSLVSKAGIIAGSKAGETRFTDTRKDEQERCITIKSTAISLF YQLPEKDLETAFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQA IAERIKPVLFMNKMDLALLTLQLGAEDLYQTFSRIIESINVIIATYSDDEGPMGNIHVDP SKGTVGFGSGLHGWAFTLKQFAEMYADKFKIEEPKLMKRLWGDQFYNYCRGFTQYILDPI YKMFEFCMPKEETLKLVEKLGIKLTSDDKDLLDKQLLKVVMRKWLPAGDALLQMITIHLP SPVSAQRYRMEMLYEGPHDDEAALGIKNCDPNGPLMMYISKMVPTSDKGRFYAFGRVFSG VVSTGMKARIMGPNFIPVKAIQRTILMMGRYIEPIEDVPCGNVCGLVGVDQYILKTGTIS TYEHAHNLKVMKFSVSPVVRVAVECKNPADLPKLVEGLKRLSKSDPLVQCSIEESGEHIV AGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETVSNTSDRTCLSKSPNKHNRLFMVA APLPDGLPDEIDRGEVSARQDQKERARYLADTYEFDVTEARKIWCFGPDGTGPNMVIDCT KGVQYLNEIKDSVVAGFQWASKEGVLCEENMRGIRFNILDVTLHADAIHRGGGQIIPTTR RCLYACVLTAEPRLMEPIYLVEIQCP---------------------------------- -----------------------------------------------------------M LPLSLLRTAVNHPMLVELKNGETYNGHLVSCDNWMNINLREVICTSRDGDRFWRMPECYI RGSTIKYLRIPDEVIDMVKEDMIQKSKGRGDSKGRGRGGPGRGAFGRGAP--VRGGRGGG GQM--------------------------------------------------------- ------------------------------------------------------------ -----------------------------------RRVLVWDLRNMGYVQQRRESSLKYQ TRCIRCFPNKQGYVLSSIEGRVAVEYLDPSPEIQKKKYAFKCHRIKEDGVEKIYPVNAIS FHNQHNTFATGGSDGFVNIWDGFNKKRLCQFHRYPTSISSLCFSADGSLLAIASSYMLDK EKPDDTVYIRRVSDQETKPK---------------VVSKDDLRRLMKEKQTLLKPEKKRI D-SPLARYNALGQLSCVLCNAPVKNELLWNAHIIGRTHKENLARKAEKEMKERAIVPPPE PPDQKKRKL--------------------------------------------------- ------------------------------------------------------------ ------------MDDELEIYRLWRIRKTVMQLCHDRGYLVTQEELDQTLDQFTQQHGDKP SERRPARSELTVLVAHNDDPTDQMFVFFPEEPKVGIKTIKTYCHRMQEENISRAIIVVQQ GMTPSAKQSLVDMAPKYILEHFLEAELLVNITEHALVPEHVVMTPEEKKDLLQRYKLKES QLPRIQEGDPVARYFGLRRGQVVKIIRPSETAGRYITYRLVV------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------------NI LVFDLGGGTFDVTLLTIDNGVFEVLSTNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRK SNRAVQKLRREVEKAKRTLSSQHQARIEIESFFDGEDFSETLTRAKFEELNMDLFRSTMK PVQKVLEDADLKKNEVDEIVLVGGSTRIPKIQQLVKEFFDGKEPSRGINPDEAVAYGAAV QAGVLSGEDDTGDLVLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQIFSTAADNQPT VTIQVFEGERPMTKDNHLLGKFDLTGIPPAPRGVPQIEVTFEIDVNGILKVTAEDKGTSN KNSITINNDQNRLSPEEIERMINDAEKFAEDDKKLKERVEARNELESYAYSLKNQIGDKE KLGGKLSDDDKEKIETAINEQISWLEGHQDADTEDYQAHKKELEEVVQPIISKLYQDTPP PGADDERDELADGVDDPELEAIRARVREMEEEAEKLKEMQSEVEKQMSPEDKIDCDSRSI WVGNVDYGATAEELEAHFHGCGSVSRVTILCDKFTGHPKGFAYIEFADKDSVDTAMALDG SFFRGRQIKVTAKRTNRPGISTTNRPPRGRIRRSRAS-YYGGYVPRGR-VSRFRSRRTAY YSPYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXPKIGINGFGRIGRLVLRAALAKVEVVAVNDPFIDLDYMVYMFKYDTVHGQ FKGTVSLVVDGKAITVFNKMKPSEIPWGSVGADYIVESTGVFTSLEKAKAHLEGGAKKVI ISAPSADAPMFVMGVNQEKYDPKMTIISNASCTTNCLAPLAKVINDKFGIVEGLMTTVHA YTATQKTVDGPSAKAWRDGRHAAQNIIPASTGAAKAVGKVIPDLNGKLTGMAFRVPVPDV SVVDLTCRLSKEASYDEIKAAVKGPLKGILGYTDEFVVSSDFIGDTHSSIFDAKAGIALS PTFVKLVSWYDNEYGYSCRVIDLITY-----QDDLATAILRKKARPNRLLVEEAINEDNS VVSLSQAKMDELQXFRGDTVLLKGKRRKETVCIVLSDDSTPDDKIRINRCVRNNLRVRLG DIVCVQGCPEVKYGKRIHVLPIDDTIEGITGNLFEVYLKPYFMEAYRPVHKGDIFLVRGG MRGVEFKVIEADPTPYCIVAPDTMIHCEGEPVKREEEEEALNEVGYDDIGGCRKQLAQIK EMVELPLRHPQLFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSK LAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKK------------------------ --------------NLDPAIRRPGRLEKEILIGVPSLQQRRDILEVLTSDVPLDIDIDLS LLAESTPGYVGADLESLVQQAHYSAIAE-----CLKQDKQIINSQEAILVKSRHFKEALH GITPSTQRGTDVDYKPIKWNDIGGLEDVKIKLKQTVEWPLKHPEAFTRLGLPCPRGILLY GPPGCGKTTIVRAMATSCHVTFLAISGGQLYSPYVGDSEQKLMQVFQQARAGAPTILFID ELDSVIGSRSQD-RDKNGVQERILSTLLNEMD--VDNNNVLLVAATNRPDLLDDAILRPG RIDHIIYVPPPDKEARVSILEVHTRKCPI-DGITVEELAVRTEGYTGADLENLCREAALY ALSE-------------------------------------------------------- --------GSNTSFGG---FGSTSNHNPMKDIEVTSPPDDSVSSIAFSPGTLPSNFLVAG SWDNNVRCWEVQTDGQTIPKAQQTHTGPILDVAWSDDGTKVFTASCDKMAKMWDLNSNQS IQVAQHDAPVKTVHWIKAPNYTCLMTGSWDKTLKFWDTRSPNPMLTIQLPERCYCADVLY PKAVVGTAGRGIIIYNLENQPTEF-------KYQHRCVSVFIDKRTNQPTGFALGSIEGR VAIHYANPQNPKDNFTFKCHRGNVQDIYAVNDIAFHPVHGTLATVGSDGRFSFWDKDART KLKTSEQLDQPISCCAFNAQGNIFAYASSYDWSKGHEGFDPQKMKPHIFLRSCFDELKPS QKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMDD QEVITTLKILIIGESGVGKSSLLLRFTDDTFDPEQSATIGVDFKVKTIQVDGNKAKLAIW DTAGQERFRTLTPSYYRGAQGCILVYDVSSKQSFQKLDNWLSELETFATKHDIVKMLVGN KIDKERREVTRDEGLKFARKHHMLFIEASAKTREGVQCAFEELVEKILQTPGLWETDGLS VGRVIWSIINGTFCSFQTRAKTQKFCRNEFNLTGLCNRSSCPLANSQYATVKEEKGVCYL YMKTIERAAFPDRLWEKVKLSRNYEKALRQINENLIYWPRFIKQKCKQRFTRITQYLIRM RKLKLRRHKKLVPLSTKVERRERRKEEKALIAAQLENAIEKELLERLKKGTYGDIYNFPQ MAFDEALKEVEVSDYDTDDAEVEYVAEDEVDLSDLSDIEFVQMRFQAQPRMKKFKIYRYD PDKPGSKPYMQEYEVDLNTCGTMVLDALIKIKNEIDSTLTFRRSCREGICGSCAMNINGA NTLACLCPIDTNTSKTSKIYPLPHMYVVKDLVPDMNNFYAQYKSIEPYLKKKDMGEDDIG KTSLKQSPKDREKLDGMYECILCACCSTSCPSYWWNGDKYLGPAVLMQAYRWVMDSRDDF KQERLEQLRDEWSLYRCHTIQNCTKTCPKGLNPSAAIAEMKRLLVGYESTGIPRQDIRPN HTIYINNLNEKIKKDELKKSLYAIFSQFGQILDIVALKTLKMRGQAFVIFKDINSATNAL RSMQGFPFYDKPMRISYAKKDSDVIAKMKGTFVERPKKKKRDSLKKKNK--ATTAIPEQP PHHILFLTNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENEGQAGAAKDALQ GFKITPSHAMKISFAKKMDSKGRKVVICDNGTXFVKCGFAGSNFPAHIFPSLVGRPILRS TIEVGNVEVKDLMIGDEASALRANLEVTYPMENGIVRNWQDMIHLYDYTFGPQKLNINPR ETKLLLTEPPMNPIKNRERMVETMFEHYQFDGLYIAIQAVLTLYAQGLMTGVVVDSGDGV THICPVYEGFSLPHLTKRLDIAGRDITRYLIKLLLLRGYCFNHTADFETVRMIKEKLCYV AYDVAQEQKLALETTVLVETYTLPDGRVIKVXRERFEAPEALFQPHLIN----------- ------------------------------------------------------------ -------------------------------------------------MTDNVGKTISC KAAVAWEPKKPLSIETIQVAPPKAGEVRIKILATGVCHTDAYTLDGFDPEGLFPVVLGHE GGGIVESVGEGVTSVQPGDHVIPLYIPQCGECKFCKSPKTNLCSKIRATQGAGKMPDGTS RFSCNGKELYHFMGCSTFSEYTVVAEISVCKVNPEAPLGKVCLLGCGISTGYGAALNAAK VEAGSTVAIWGLGAVGLATIMGCKKAGASRIIGIDINPEKFEKAKEFGATECLNPKDYQE PIQTVLINMTDGGLDYTFECIGNVATMRAALESCHKGWGTSVIIGVAAAGQEISTRPFQL VTGRVWNGTAFGGWKSTQSVPKLVDAYLRKELKVDEFVTHTMSLDKINEAFDLMHGGQS- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------KDETIETEKASY TLPDGNLLEVGPARFRAPELLFRPDLIGEECPGIHEVLTSAIFKSDMDLRRTLFANIVLS GGSTLFKGFGDRLLSEVKVLAPKDIKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKR EYDEDGAKAIHRKTFDPHKISNVVVHPLVLLSVVDHFNRMGKIGNMKRVVGILLGSNRQG VLDVSNSFAVPFDEDDKEKDVWYMDHEYLENMYAMFKKVNARERIVGWYHTGPKLHQNDI AINELIKRYCQNSVLVIIDAKPKDLGLPTEAYISVEEVHDDGTPTTKTFDHVPSEIGAEE AEEVGVEHLLRDIKDTTVGTLSQRISSQLSGLKGLQSQLEDIQTYLEKVSSGKLPINHQI IYQLQDVFNLLPDVNLPEFVRSVYIKTNDQMLVVYLAAMIRSIIALHNLINNKIQNRDAE KNESGKSEMGLLLSKLWSLFSNEEHKVIIVGLDNAGKTTILYQFLMNEVVHTSPTIGSNV EEVIWKNIHFIMWDIGGQDSLRTAWNTYYANTEFIILVIDSTDRERLSITKQELCNMLAC EDLKKAAVLVFANKQDLKGAMSAAEISQQTHLTXIKDHGWHIQACCALTGEG-------- ------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXX----------------TVYSMNWSVRPDKRFRLALGSFVEEYNN KVQIVSLDEETSDFVCRSTFDHPYPTTKIMWIPDSKGAYPDLLATSGDYLRVWRVTRQEC LLNNNKNSDFCAPLTSFDWNEVDPNLLGTSSIDTTCTIWGLETGQVLGLVTGHVVTPCV- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------RSFSSSSKVT VCGASGGIGQPLSLLLKLNPRISHLALYDIVHSPGVAADLSHISTKAKVTGHLGPEQLRT AIEGADVVVIPAGVPRKPGMTRDDLFNTNASIVRDLADATAQYAPKAIVCIISNPVNSTV PIASEVFKKRGTYDPNRIFGVSTLDVVRANTFIAEAKDLDVSQVNCPVVGGHSGVTIVPL ISQCTPPVSFPQEVRDKLTKRIQNAGTEVVEAKAGAGSATLSMAFAGARFTDSVLQALAG EEGVVECAFVRSDETEAKYFSTPLLLGKNGLDKNLGLGKVLDYELNLIKAALPELKKNIQ KGEDFVLK---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -SPRNTYQSAMGKQAMGVYITNYHVRMDTLANVLFYPQKPLVTTRSMEYLRFRELPAGIN SIVAIATYTGYNQEDSVILNESAVDRGFFRSVFYRTYKDAESKKGLDQEELFEKPDRKYV TGMRHAVYDKLDADGIIAPGTRVSGDDVLCGKTLTLPENEDELEGQVKRFTKRDCSLFMR RSETGIVDQVMVTINQEGYKFIKIRVRTVKTPQIGDKFASRHGQKGTCGIRYRQEDMPFT CEGVTPDIIINPHAIPSRMTIGHLIECLQGKVSAIKGEIGDATPFNDTVNVQKISKLLHE YGYQLRGNEILYNGHTGRKLNAQIFLGPTYYQRLKHMVDDKIHSRARGPVQILNRQPMEG RSRDGGLRFGEMERDCQIAHGAAQFLRERLFEVSDPYRVHVCNLCGLIAIANLRNNTFEC RGCKNRTHISQIRLPYACKLLFQELMAMSIAPRMMVLCAEPKGGFSFENCKRNAVLLKGL KPPSAYKTGTTICGIVFKDGVVLGADTRATEDTVVADKNCSKIHYLADNIYCCGAGTAAD TEMTTQLIAAQIELHRLNTGRKPRVCTANRMLKQMLFRYQGYISAALVLGGVDITGPHVY SVYPHGSTDSLPYVTMGSGSLAAMSVFEDRYKVDMEKEEAMRLVCDAIRAGIFNDLGSGS NVDLCVITKKVEYLRPFDEANQKGKRQGDYSYKRGTTAVLNEEVKKIEVDIIMSKVTFKI TLTSDPKLPYKVLSVPENTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPSQNAGNVFL KHGSELRLIPRDRVGHMAFTFVAFCYILALILSAFLIFFVIYHIIAFDELKTDYKNPIDQ CNSLNPLVLPEYLLHLFYNVLFLFAGEWFTLVLNVPLIAYHIKRYMNRPVMSVPGLYDPT SIMNADELNRAQKEGWIKLAFYLLSFFYYLYSMIYELVSSMGLLTILKKMKQKEKEVRLL MLGLDNAGKTTILKKFNGEDINTISPTLGFNIKTLEHRGYKLNIWDVGGQKSLRSYWRNY FESTDGLIWVVDSADRRRMQDCKQELDSLLVEERLAGATLLVFANKQDLPGALKAEEIKD ALDLESIQSHHWLIQGCSAVTGENLLQGMDWIIKDISSRIFTMD---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------FKLHISPSNMANQNTADYLDKIKNRLFENLRMIPHAPGVQM QDIEEDAIKDE--------------------------------------------ENGTF ECNICLDTARDAVVSMCGHLFCWPCLHQWLETRPNRQVCPVCKAGISKEKVVPLYGRGST NQQDPRDKVPPRPAGQRSEPENNSNFPGFGFGLHFSFGIGAFPFTFFASTLNLSDGRPQP PSVGTPQYAEERFLSKVFLWVAILFIFWLLIA--ALIHKQEQAHEDSIWSCAWAKSEKDG TENIVTGSVDDTVKVWKWHDLELRHTLEGHQLGVVSVDINAQGTMAASNSLDSHIRLWDL EAGKQVKEIDAGPVDAWTVCFSPDSRFLASGSHLGKINLFGVESGKKESELDTRGKFTLS IAYSPDGKYIACGAIDGIINTFDMTVGKLLEGHAMPIRGLCFSPDSRLLVTASDDGHIKI YDVQHANLAGTLSGHGSWVLNVNFSADNIHFVSCSSDKTVKVWDSGSRTCVHTFYDHTDQ VWSAKYNQAGTQIASVSEDRAIHVYNVPVESDEEFDARYEAAFNDPNTDGWLIRKLMNDL HGYDLVPEPKIIIAAMKACRRVNDYALAVRYLEAVKLKCDKNLDQIWPWMLQEIGPTLKE LGIDTPEELGYDKPELAKVNVYDI------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------NYISQTGHSVHMRGLPFAATEQDILDFFKPLNPVNVVIH YNNGRASGEADVDFATHEEAKEAMNKDRSSMQHRYIELF--------------------- ------------------------------------------------------------ ---------------AQKLLDKGIHPTIISEAFQRAAEKSTEILEEMSMPLELTDRESLL KSATTSLNSKVVSQFSNTLSPLCVDAVLKVIDPKKDTNVDLHDIKIIQKLGGTVEDTELI EGLVFNQKSAGFGGPHIIEKAKIGLIQFCISPPKTDMESQVIVSDYTQMDRVLREERQYI LNIVKQIKKTGCNVLLIQKSILRDAVNDLALHFLAKMKIMVVKDIEREDIEFVCKTLGCR PVASLDHFQADTLGSAELVEEVAVGESKIVKITGITNQGKTVSILVRGSNKLVL------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------QKTDARKGDNIGYITFVLFAR HEARDNTINLIHMLRDYLHYHIKCSKAYIHSRMRAKTSDFLKILNRARPQ-QVKDKKTIX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKKVFGPLKDEDRIF TNLYGRHDWKLKGALKRGDWYKTKEIILKGHEWIQGEIKKSGLRGRGGAGFPTGMKWSFM NKPSDGRPKYLVVNADEGEPGTCKDREIMRHDPHKLIEGCLVAGSAMGACAAYIYIRGEF YNEASSMQIAIKEAYDAGLIGKNACGSGYDFDVYLHRGAGAYICGEETSLIESLEGKPGK PRLKPPFPADVGVFGCPTTVNNVETIAVSPTICRRGGDWFASMGRPRNQDVMMDFDALVE KQSALGTAALIVMNKSADVVKCIARLMEFYKHESCGQCTPCREGVSWMNTILQRFVTGNA RPDEIDMLQEISKQIEGHTICALGDGAAWPAQGLIRHFRPELERRMKEYHEK-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------DREDITEPAVCALRHLTSRHSDAQMAQNAVRLHYGLPVLVKLLHP PSRWPLIKAVVGLIRNLALCSANHAPLREHGAIPRIVQLLFRAHQDVQKNTGAYVDGVRM EEIVEGTVGALHILARETNNRAVIRGLNCIPLFVQLLYSPIENIQRVAAGVLCELAADKE GAEIIEQEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRGE QMSAEVQWMVIRNTSSFLVKRRHFSTDPHNLKNIHSPRYNGLIKKRTVGVEPAEDGKGVV LVTRTGWRKPAKNYSRIELKRDARRNLTSIRNVLR--HYRRDLKMPALRRASAILRSQKP VVVHKPKDEPYYCAEQINIPPELPDILKQFTKAAIRTQPKDVLAWSAAYFRAMANGEMPP VKERLEMPTATQKTDTGLTPGLLRILNKQLGPKKIVSLSLIEEKWRSLALPMEQFQELVR IGNFGGDIEWLKFFALGCAALGDNLTSTMKTVCEILTADPDGGPARIPFPLFQDLYKYLA SIDGEISSEHVNSVINYLTYQVDKQDGFIQPRNFLAPDCPSLSXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXMNRLFGRAKPKAPPPNLNDCISNIDSRAESIDKKISRLDQELAKYKDQMKKMR EGPSKNMVKQKALRVLKQKRMYENQREQLSNQSFNMEQSNYAIQSLKDTKVTVDAMKVGV KEFKKEYKKINIDQIEDLQDELEDLTEQAGEIQEIMGRSYGMPDVDEAELEAELDALGDE LAFDEDTSYLDEASAAPNAPTSVPGSESATNKDGVPVDEFGLPQIPAQXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----KKARDAQEKSRAALQRYLFYCNRYMNHMQSLKFENKLYATIKYKMEDMQQHNMSW IEVQFLKKAVDVLCQCRQTLMFTYVFAFYLKKNNQSIIFEDNQKDLENATEQLSEYLERD ITDDMLVDIKQKVQDKYRYCESRRKVLLDHVHEGYEKDLWEYND---------------- ------------------------------------------------------------ ----------------------------PSTTRYLFLGDYVDRGYFSITERVYDGCMESF DCLPLAALMNQQFLCVHGGLSPEIHNLDDIRKLDRFKEPPAFGPMCDLLWSDPLEEFGNE KTTEHFTHNSVRGCSYFYSYAACCDFLQQNNLLSIIRAHEAQDAGYRMYRKSQSTGFPSL ITIFSAPNYLDVYNNKAAILKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVT EMLVNVLNICSDDELMNEEDDTFEGAVAARKEVIRNKIRAIGKMARVFQVLREESESVLQ LKGLTPNGLLPIGALSGGKESLKSALTGFNPSHKISGFEEAKYLDKLNERMPPRK----- ---RGGGRGGRGG------------GRGGR-GMAGGRKVIVEPHKHEGVFIARGKEDALV TRNLVPGESVYGEKRIAVEDGVKTEYRAWNPFRSKLAAAILGGIDNIHMKPNSKVLYLGA ASGTTVSHVSDIVGPEGLVYAVEFSHRSGRDLINVAKKRTNIIPIIEDARHPHKYRMLVG MVDTIFADVAQPDQARIVAINAHHFLKTGGFIVISIKANCIDSTAEAEAVFAGEVNKLRS EKMKPKEQITLEPYERDHAVVVAQYRPPPKKMDKNKLNDLAGRLQKGGRGAGIGLGFLAA AGGVAYGLYQSLYTVEGGHRAIIFNRIGGIQQDIYREGLHFRIPWLQYPIIYDIRARPRK ISSPTGSKDLQMVNISLRVLSRPDATKLPTIYRQLGTDYDERVLPSICNEVLKSVVAKFN ASQLITQRSQVSLLVRKELIDRASDFNIILDDVAITELAFSREYTAAVESKQVAQQETQR AQFIVEKAKQERQQKIVQAEGEAAAAKMIGEAISSNPGYLKLRKIRAAQNIARTIAASKN RVYLNAGSLMLNVNDSTFDENLDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPDPDA IKMFVGQIPRSMDEEDLRKMFEEFGMVFQLNVLRDKVTGQSKGCCFVTFYTRKAALEAQN ALHNIKTMAGMQHPIQMKPADSEKL--EERKLFVGMLSKKCNENDVRMMFSPFGQIEECT VLREQNGQSKGCAFVTYTSKQCAQNAIKSMHHSQTMEGCRSPLVVKFADTQKEKKMKKLQ QMQNALQLQLTGGTIGGIVTVYVGQPLDTVKVKMQTFPAAYRNSLHCFVQTFKELGAKGL YAGTVPSLENAILFVAYGLCQKAICCASFFSSLALCPTELIKCRLQVMIKHILKHEGIQG LFHGLNATFAREMPGYFFFFGGYXTCRTLLTPAGQTKDDL------------------GL PPDVLKSRLQTREEGIGALYKGATPVMLRAFPANAACFLGYEVAMKALNDHSNDFTRLSQ VVGNNIQKISQNVGQMQRMINQIGTPQDNDNLRDRLHQIQHYTGQLAKEANRSLKDLAHL QSEQRQWKMQKERLTSEFTSVLNSFQVAQRKAAEKEKESVEDVDLQIIQEREKAIRQLES DIMDVNQIFKDLGMLVHEQGEMVDSIEANVQSINVESGAQQLQKARE------------- -------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXGKKGEKAPTTQEAIQKLREVEEMLSKKSDFLEK KIEVELSIARKRVALNALKRKKRYEKQLQQIDGTLSTIEFQREALENANTNTEVLSVMGG AAKALKATQKNMDVDDVHNLMDDIAEQQEIATEISDAISNPIGFGQDIDEDDLMAELEEL EQENLDEQLLEVTNLPSVPTTEDSEIDELAMWAS-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TTRTVNKHGDEIITSTTSNYETAT FSSKTEWRVRAISATNLHLRTNHIYVSSDDIKETGYTYILPKNILKKFIVISDLRAQIAG YLYGVSPPDNPQVKEIKCIVMPPQWGTHQMVHLPNNLPNHEYLKTMEPLGWIHTQPNELP QLSPQDITTHAKIMAENPSWDGEKTIVITCSFTPGSCSLTAYKLTPSGFEWGRQNKDTGN NPKGYLPSHYEKVQMLLSDRFLGFFMTPATSSWNYNFMGVRHDPNMKYDLQLANPKEFYH EIHRPSHFLNFSSLEEGADRENFYSVYVKTRPRLAINKDTKVICQGFTGKQGTLHSQQAI EYGTQMVGGVSPGKGGKTHLGLPVFNTVKEAKDATGADASVIYVPPPFAAKAIMEAIDAE MGLVVVITEGIPQHDMVRVKNHLLQQDKTRIVGPNCPGIIKPGECKIGIMPGHIHKAGNI GVVSRSGTLTYEAVYQTTQVGLGQSLCVGIGGDPFNGTNFVDCLDVFLKDPNTEGIVLIG EIGGQAEEKAAEYLKENNGPNYKPVVAFIAGLTAPPGRRMGHAGAIIAGGKGGAQEKIKA LKEAGVHVSMSPAQMGSTIYKAMEKIGKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFKRFVEIGRVAYIA TGPDAGKLVAIVDVVDQNRVLVDGPCTGVGRRILNLKQLDLTNFVLFSHTARTRVVRKEW EKAEIDKKWAETTWAKKMANKEKRAALTDYERFKLMKAKQTRNRIINLQFRKLKNDMKKT CPLLLRVFCSTGRHHMLSEYARGNTPANELQIYTWMDATLKELMSLVKEVNVDARRKGTY FDFAIVTPDTRSPVYRMNEIGSTCAGMKGKDDGVTLASKRFQIGDYLDIAITPP------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----KSDVEKGLPPKQETKIYIGLSKMQREWYTKILMKDIDVVNGAGKSDKMRLLNILMQ LKKCTNHPYLFDGAEPGPPFTTDQHLVDNCGKMVLLDKLLPKLKEQDSRVLIFSQMTRML DILEDYCYWKNYDYCRLDGQTPHEERQKSINEFNMPGSKKFVFLLSTRAGGLGINLATAD VVVIYDSDWNPQADLQAMDRAHRIGQTKVVRVFRFITENTVEERIVERAEMKLRLDNVVI QQGRLVDGTTNKEVLSMIRHGAENVFASKDSTITDEDIDALLKRGEEKTRELNKKLDKLG ESSLRTFTLDTEEKSVYQFEGVDFRERHKISGIGHWIEPPKRERKANYAVDAYFREALRV SEPKAPKAPRPPKQPNVQDYQFYPPRLFELLDREIYYYRKTIGYRVPKDPDLGADAERVR -------------------------RGFSNWSKRDFNQFIKANEKYGRDDLESISKEVEG KTPEEVMEYSSVFWDRCSELQDIERIMAQIERGEAKIQRRISIKRALDAKMARYRAPFHQ LRIQYGTNKGKNYTEEEDRFLVCMLHKLGFDRENVYDELRTAVRQAPQFRFDWFIKSRTA MELQRRCNTLITLIERENMELEEREKAEKRRDSKPSWADQVEQGEDATLPPPHEDFDENK GTKTITEIRFNDEGKKVKIVKTYKIETRKVSKSIARRKTLKKFGAAAGDPPGPNPANTYE DVFFQFVRNMEH-EDDPLSKLKVSCRICKGDHWTTRCPYKDTLAPIHDALSRPGKYVPPN LRDGGSRRGEAMTPDDTATIRVTNLSEDTRETDLQELFRPFGSIARIYLAKDKNTGQSKG FAFINFHRKEDAERAIAGVSGFGYDHLILNVEWAKPSXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- ----------------RILRVEKTGHSGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYV CIFRLHSAIENETKLAAVISTLTGALFQRPPLISAVKRQLRIPTIYDSKLIEYDKEKNMG ILWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGIQSETDGLVTMHDVLDAQWVYD HQKDESYLRRVIKPLEALLVSHKRIVIKDSAVNAVCYGAKIMLPGVMRYEDGIEVNQEIV IITSKGEAVALAIALMTTAVISTCDHGTVAKIKRVIMERDTYPRKWGLGPVAMKKKAMIQ QGLLDKYGKPNENTPKNWVSTYTYLTGTSKRKHDTPSTEKKKKKKKSKMAEADWDRKRQP KASQLKSQKAINAAQRAGGEIETTKKWTAAQNKQHMAARNTAKLDRETEELHHDKVGLDV GKLIQQGRQQKGLTQKELATKINEKQQVINEYESGRAIPNQQILSKMERTLGIKLRGKNK GQPL---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXAAATARISSKKQTLDDAYAPPANFLEIDVLNPEGKKRYTDYEVRMRTN LPVFKVKESSVRRRYSDFDWLRCELERDSKIVVPPLPGKAWSKQLPFRGDDGIFEEDFIE ERRKGLEQFINKVAGHPLAQNERCLHMFLLEPVIDRNYVPGKVRTT-------------- -------------------------------KIYDRDEESSSSKEIKARAHTYYQVLVDG RDIPHIRVGAETVTFLSNQGNGTLYSIPGLDYVSHEDVLPYRTTEKQPIHNHLFDKFLAT DPNYVARDSLRDWQDKNHPWLELTDVHRETTENIRVTVMPFYIGVVQQQHVYWWRYCIRL ENLGEETVQLRERHWRIFSLSGTLETVRGRGIIGKEPVFSKAQPAFQYTSHISLQAPSGH MWGTFKMEREDSSTFECRIPPFSLESKQEDG----------------------------- -------------------------------------------------NICQTCLLDLE YGLPVQVRDAALKIQDEMPKSDVNKEYYTQNMEREIAQTDGTTPVGAVGKAMAPSDMLLK LARTTPYYKRNRPHICSFWVKGECKRGEECPYRHDKPTDPDDPLADQNIKDRFYGINDPV ADKLMRRYNSMPKLEPPEDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXHLYRYHAVLLRARFDEHKNEDVLRAKKLLEEGEAELKKYHHPQPIKFANSPGGVA YGREVKPPDWCLDMWHPLERAQYPEYFKRREQRKLEFIENWEKKYGKPEMDDYIKIEKIG EGTYGVVYKGRNKITNKTVALKKIRLESEEEGVPSTAIREISLLKELQHPNIVRLEDVLM QENKLYLVFEFLSMDLKKYMDTIPSGQYMDTMLVKSYTYQLLQGIVFCHQRRVLHRDLKP QNLLIDSKGVIKLADFGLARAFGIPIRIYTHEIVTLWYRAPEVLLGSQRYSTPVDIWSIG CIFAEMVTKKPLFHGDSEIDQLFRIFRTLTTPTESTWPGVSSLPDYKPXFPNWQTNTLKQ SVDPAGLELLQSMLIYDPSXRITAKTALQHPYF--RLFNTLGKLGLGIALAGGVANSALY NVDGGHRAVIFDRFAGVKDQVVGEGTHFLIPWVQKPIIFDIRSRPRSVPTVTGSKDLQNV NITLRVLFRPLPTKLPKIFTTLGVDYDERVLPSIINEILKAVVAQYDAAELIMQREVVSQ KINEELMNRAKQFGIMLDDISITHLSFGREFTDAVEMKQVAQQEAEKARYVVEKEEQRKK AAIIRAEGDSQAAILLAKALGDAGEGLVELRKIEASEDIAYQMSQSPNVIYLPPGQQTLL SLP-KTIRANQVVLIPEGVNAKIKSRRVVITGPRGTLRRDFRHMQVDIKKL-KKRIIVEK WFAIRKELAAVRTVCSHIENMIKGVTKGYRYKMRSVYAHFPINISITEDNTMVQIRNFLG EKYTRNVKMLPGVTCVASEKQKDEFILEGNDIELVSRSAALIHQSTKVKNKDIRKFLDGI YVSEKGHVTEEMGCAVSSDDKVAQERSKAIDKSLRADGERASREVKLLLLGAGESGKSTI VKQMKIIHEKGYSQEECLQYRPVVYSNAIQSMIAIIRAMGQLKIDFGHPDRADDARQLFA LAGNAEDGELTPEIAAIMKRLWKDSGVQECFSRSREYQLNDSAEYYLSSLERISQPNYVP TEQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFIVAMSE YDLTLAEDQEMNRMMESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLSICFPE YTGANTFEEAAAYIQLQFNKRKDTKEIYTHFTCATDTNNVQFVFDAVTDVIIKNNLKDCG --KKYAEMKRMINLRDKRISKKDCQNKKRRKPNPQNLTIREIPQVSSALFFRYNTQLGPP YHILVDTNFINFSIKNKLDIVQSMMDCLYAKCIPYITDCVMAELEKLGRKYRVALRIAKD ERFQRLPCLHKGTYADDCLVERVTQHKCYIVATCDKDLKRRIRKIPGVPIMYLQQHKYSV ERMPDAFGAPKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX--------------------------------------------- ------------------------------------------------------------ ----------------------------------------------------FSLLLGNS VIIDLMGIAIGHIYYFLEDVFPEQPRGFKVLHTPAILKYLFDPVPEDPNYNPLPPGGFDW GQSIDLLSDQGFRIDGRKPKELRRIQTKLGVFAQADGSAYIEQGNTKVLAAVYGPHEVRG SKSKHDKALLNCQYSMAVFSTGERKRRPRGDRKSMEMTQHLQQTFEAAILTHLYPRSQID IFVEVLQSDGGNYCACVNAATLAVIDAGLPMKDYITACSASIVSDTPIVDINHFEESGGI ELLLAILPKSSHIVFMEMNGKLHEGYLEKVIDMAMMGCNDIYNILDQAVRDMAGNYYFVI VAQYDNPIFEMEFTPLNKASDPKRDDHRHLNQFIAHAALDHVDEQMWTTNNMYLKIVDKF NEWFVSAFVTAGRMRFIMLHDAKNEDGIKNFFQDTYETYIKYAMNPFYEPNTAIRSPAFE KKIQVYGRKYLKSQIRLAHTDVKVPDFSAYRRDSTQDARRTFTYMMLAAGTVPTLYAGKA LAAEFVLSMSATADVLALAKVEVNLADIPEGKNAVFKWRGKPLFVRHRDAAEIAREEAVD ISILRHQETDQERVQRPEWLVTLGVCTHLGCVPIANQGDFGGYYCPCHGSHYDGSGRIRK GPAPLNLEIPPYEFTSENTLVVGMSRQTARGVDPRKVSGELFTLTYGALVSQLLKDYEND AEVNKQLDKMGYNIGIRLIEDFLARSNASRCNDFRETADAIAKVGFKMFLGIVPVVTNWS AAGDEFSLLLENNPLTDFVELPDGHGSLNYSNILCGVLRGALEMVEMEVAVWFVQDQLKG DNLTEIRLKFIKRL-----------VRAFLAQAREDFLKKWEDPISNNAGLDDFDRIKTL GTGSFGRVMLVQHKATKEYYAMKILDKQKVVKLKQVEHTLNEKRILQAINFPFLVRLEYS FKDNSNLYMVLEFVTGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKP ENLLIDSQGYLEVTDFGFAKRVKGRTWTLCG----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -MLSDTLLILFISVATAFLGEGLTWLLVYRTDKYKKLKAEVEKQSKKLEKQKEIIGDVTD RSHKKKIERQEEKLKSNSRDLSLVKMKSMFATGFAFTALLGMFNSIFDGRVVAKLPFVPI SLLQSISHRNLIGDDYTESSFIFLYILCTMSIRQNIQKLLGFAPSRAANKQGSGLFST-- ------------------------------------------------------------ -------CAAELVCKEWYRVISDGMLWKKLIERMVITDSLWHGLAERRGWISHLFKPKPG EPLKNNKFYRELYPQIIQDIDRIENNWRTGRHTLKRIHCRSETSKGVYCLQYDDEKIVSG LRDNTIKIWDRNNLDCIQVLTGHTGSVLCLQYDDNIIVSGSSDSTVRVWSVKTNEMLNTL IHHCEAVLHLRFADGIMVTCSKDRSIAVWDMQSSTDIGLRRVLVGHRAAVNVVDFDQKYI VSASGDRTIKVWSTSTCEFVRTLNGHK--------------------------------- -----------------KRIVSGAYDGKIKVWDLAAALDPRAPSGTLCLRTLVEHSGRVF RLQFDEFQIVSSSHDDTILIWDFLN-AKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNS TFISTIGIDFKIRTIELVGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITCEKS FENIRNWIRNIEEHASSDVEKMILGNKCDMNEKRQVSKQRGEALAIEYGVKFLETSAKAS INVEEGFFTLARDIKAKMDRKL-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------G AQFVKGFGGIGGILRYQVDFQSLEPLDDIDETFDLDEYITRSSQPLVGRRSAPDERYIEM IINTNTKSLKLYIMDARPMVNAVANKAKGGGFESEDAYQNAELVFLDIHNIHVMRESLRK LKDICFPTRDDAHWLSSVESTHWLSHIKQILAGATRIVDKVENHKTSVLVHCSDGWDRTA QLTALAMLMLDPFYRTIEGFEVLLEKEWISFGHKFQMRIGHGEDKHNDTERSPVFLQFID CVWQITQQFPHAFEFNEQFLITILDHLYSCLFGTFLYNTDKMRHEEKLKTNTVS------ --------------------------------RWNPRMKPQEPIHLRYRELLSLKAQLQE RLEELQRQIEYQNSPFKPFIPHLPFDLVQCETIFPRAKPAPDDKPMAEALLKRAQDLTPT PQEQASVLSLVTKINSVLENLVIAPGGFDAAQLEEVRQVGSFKKGTMMAGHNVADIVVIL KTLPTVEAVQVLGNKLIEELKQTDPHEVLTMLTNESGFEISSSEATVKVLVT-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------EVNVVPPSRLLALLGQALKWQQHQGLLPPGTTIDVFRGKAAV REQEEEKYPTQLSKTIKFGQKAHVECAKFSPDGQYLVTGSVDGFIEVWNFSTGKIRKDLK YQAQDNFMMMDDAVLCMNFSRDSEMLATGSQDGKVKIWKIQTGQCLRRFERAHAKGVTSI TFSRDNGQLLTASFDQIIRILGLKSGKTLKEFRGHTSFVNDAVFAADGQHIISASSDGTI KVWNIKSTECSSTLKSLGGTGGSDATVHSIHPLPRNTEQFAVCNRSNTIVLMNMQGQIVR SFSSGKREGGDFVCACLSPRGEWIYCVGEDLVLYCFSLQTGKLERTLTVHEKDVIGIVHH PHQNLIATYSEDGLLKLWKPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------LPKDMQECNWFSAPSALRVYGQYLNLDKDHNGMLSKQ ELARYGTGTLTSVFLDRVFQECLTYEGEMDYKTYLDFVLALENRKEPQALQYLFRLLDVE NKGYLNVFDLNFFFRAIQEQMKYHQQDPVSFDDVKNEIFDMVKPADPYKITLNDLIKCGQ GDTVISILIDMNSFWSYENREVEMVRGQPFEVGPRYRNLAYIGEGAYGMVVSALDYVTNQ KVAIKKISPFEHQTYCQRTLREIKILTRFKHENIINIQDIIRAPTVEEMKDVYIVQCLME TDMYKLLKTQKLSNDHVCYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFG LARVADPDHDHVGFLTEYVATRWYRAPEIMLNSKGYSKAIDVWSVGCILAEMLSNRPLFP GKHYLDQLNHILSVLGSPSQEDLNCIINDKARGYLQSLPFKPKVPWNQLADPKALDLLDK MLTFNPNKRITVEDALSHVYLEQYYDPADEPVAEEPFTFETELDDLPKEKLKELIFKETV LLKERELSPPKTTPEWVKFCKQLFGGFSTLLWIGAILCFVAYSIQASTYEDPPGDNLYLG IVLTAVVVVTGCFSYYQEAKSSKIMESFKSLIPQFAIVVRNGEKLNIHAEELVVGDLVEV KFGDRVPADIRIIQAHSFKVDNSSLTGESEPQTRTADFTSDNPLETRNLAFFSTNAVEGT CRGIVVSTGDRTVMGRIANLASGLEMGETPIAKEIAHFIHIITGVAVFLGVSFFVIAFIL GYHWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTI CSDKTGTLTQNRMTVAHMWFDDRIVEADTSDDQSYATYNKDSVTWMNLARIAMLCNRAEF RSGQEGVPVLKRECNGDASESALLKCVELSIGHVTDFRKNNPKVCEIPFNSMNKYQVSVH P----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------NLFFETALAAFLAYCPGLDKG LRMYPLRFTWWLAPMPFSLVIFIYDEVRKYLLRKYPGGWVEQETYYSFKNLSKGKKIAAG VAAGAVGLGVALQDLELHPPSYPWSYKGIFDSYDHASVRRGYQVYKQVCAACHSMDFMYY RNLVGTIMTEDEAKAEAAEIQVVDGPDDEGNMFKRPGKLSDRFPQPYANEEAAKAANSGA YPPDLTFIVNAREGGADYIFSLLTGYCDPPAGCEEREGLHYNPYFLGGYIAMAKALYNEV VEYDDGTPATGSQLAKDVTTFLAWAAEPEMDDRKRMGIKTILVLLLFFSFYYKRVKWLPV KTRKIAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMP EIMRLITKDLSEPYSIYTYRYFIHNWPKLCFLAMDGSRCVGAIVCKLDMHKKMIRRGYIA MLAV------------------------------------------------FVRDKRLF RYYLNGVDALRLKLWLRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------------------- ------------------------------------------------------------ ----------------------------------------------DDVVVSATNFSSER MCPIFQVSNVSGENLDLLKMFLNLLSTRMSNEPAEFQIDDTFSVPGVGTVISGTTLRGEI HLNDTLLLGPDLLGNFIPIAVKSIHRKRMPVKEVRGGQTASFALKKSQIRKGMVMLSPKL DPKACWEFEGEILVLHHPTTISVKYQAMVHVGSIRQTATIMSMSKEHLRTGDKATVRFRF IKNPEYLRTDMRMVFREGRTKAVGTVTKLFPHISLNTRQQRASKKAAE------------ ------------------------------------------------------------ -------LVTGSKDKSVKVIQIHTGQVQQTVSSHSGAVTCVRLNYSNLLATGSHDKTINM WDFLYTIQ-CTAAVTHLTLSADNTFLLYACKDNSVQVASTVFHELIDNKIQIGNIALSKD SVHCAVGGLDGHLYIYNLRSKELLDTFTA-GGPLCDVTVTEDDHFFFTACKDTFFKRTTN DTDNSHTKAITCYCMSVEGKMAITGSDDCLVKLWNLDISDFLGNLEGHTKPVTSVSVAAQ EAFAVSGAEDNTVKVW-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXX-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------HTLQQTENDLEAQHTATDYATRKRIHEFERAIDELNWQKQQTEEEIAELEEDI RRLNDAIRAKINPLKLAQTRLENRTYRPNVELCRDNPQYGLTDEVKQLEASKRALEEKLX QSQHALDGLXQNL------------------------------------TNLKDVLANEI PEQQRQIKEFRAKHNNTVVGDVTVDKIYGGMRGILGLATETSLLDPEEGIRFRGLSIPEC QKLLPSAPGGEEPLPEGLFWLMVTGKVPTEAQVKAVSKEWANRADLPSHVVTMLNNFPAN LHPMAQFSAAIIACNSESKFAKAYSEGVKKANYWEYCYEDAMDLVAKLPTIAAIIYRNLY RDGTSVGAIDPAKDWAANFVSMLGYEDPKFVELMRLYLTIHADHEGGNVSAHTCHLVASA LSDNYLSYGAGMCGLAGPLHGLANQEVLLFL-KVMYSLDQLKEFVWKTLKSGQVIPGYGH AVLRKTDPRYTCQREFALKHLPNDPMFKLVSDLYKVVPDILLELGKVKNPWPNVDAHSGV LLQYYNMTEMNYYTVLFGVSRALGCMASTIWDRALGLPIERPKSITTVALMEKV-MPFQP PKTEKCATCGKSVYAAERMEAGGNIYHKLCFKCATCKMPLKLNNYQQNEGKLLCKTDYQK EILAKNAQIDKIFVHRDTPENNPDIPFEFSAENLKRAKDIIGNYPEGHQTAAVLPLLDLA QRQHGWLPISAMHYVADLLKMPKMRVYEVATFYTMFNREPIGKYHIQICTTTPCMLGGVG CGPILEAIKKQLGIEVGETTADKMFTLSEVECLGACVNAPMVQINDDYYEDLTEKDIIEI LSDLKAGKKPKPGPRSGQNGRFASEPKGGLTSLKEPPYGPGFKVRADLMLKYEKLEKIGE GTYGTVFKAKNKETHEVVALKRVRLDDDDEGIPSSALREICLLKELRHKNIVRLYDILHS EKKLTLVFEYCDQDLKKYFDSCNGEIDPAIVKSFMYQLLRGLAFCHGKNVLHRDLKPQNL LINK-------------------------------------------------------- -----------------------------------------------------QQVVPKL NSKGRELLLSLLVCNPTKRLSADEAMQHAYFSDLNPSVRSESRWLKFEGPKPDVTYPVKD VCDGWPLEYCEYHPNYAQAKEWMEQNLSDDIKALYLKAQKRGGRGVIKTKKKQEEQRVCL ARAPRGKRKFVTIVTGLSTCGIDLKVASKYFASKFSCGSSVTGDDEIVIQGDVKDELFDV IPEKWPQIDEENIDDLGDQKRYFCCDRSASWKHRHEKLCGTLEAANSILYGTPEIWSKYY FSCSPPGGLMAIRPHGFSGVLLPDKEMLVTDAGKLFVLDSLLQRLKVEGHRVLIYSQMTR MIDILEEYMWHRKHTYMRLDGSSKISERRDMVADFQTRSDIFIFLLSTRAGGLGINLTAA DTVIFYDSDWNPTVDQQAMDRAHRLGQTKQVTVYRLICKGTIEERILQRAREKSEIQRMV ISGGNYCPDVLKPKEVVSFLLDDDEMEKKMSLETVPKDLRNLRACLLCSLVKTIDQFEYD GCDNCEEFLHMKNNRDAVYECTSSNFDGIISLMSPEDSWVAKWQRINRHVKGVYAISVTG RLPPGIISDLKSKGIVYRPRDFSMPRFVPYLTKEQEDELRKIANAIAAPGKGILAADEST GTIGKRFSQINVSNEEENRRQYRQLLFTSLGEHISGVILFHETLYQKTDDGTPFVKVLQD NGIIPGIKVDKGVVPLAGSDGECTTQGLDGLAERCAQYKKDGCGFAKWRCVLKIQSHTPS LQAMIENANVLARYASICQQNGLVPIVEPEVLPDGEHDLETAQKVTEQVLSFVYKALADH HIFLEGTLLKPNMVTAGQSCPKKYTPQEVAVATVTALQRTVPPAVPGITFLSGGQSEEDA TIHLNAINQKPWALTFSYGRALQASVLKAWQGKSENVKAGQAELLKRAKANGEAALGQYK GGEKGAAGESLFVANHAYYIQSLPKPVKRRIKALKKLQFKTIEMEAKFYEAVHELECKYT EMYAPLFDRRREILTGSLEPTDSDCDWPSDEEEEEQKAKVEEEENVSGIPEFWLTVFKNV EMLSEMIQEHDEPILKHLQDVKVNFQVGFTLEFHFSPNEYFTNSVLTKEYIMRCEPDEND PLSYEGPEIIKCKGCKIDWNKGKNVTIKVIKKAQTHRGRGTKRILTKTIQRDSFFNFFNP PDVPEGTASEDTEQILGADFEIGHFLRERIVPRAVLYFTGEALEEEEENDEDED------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------TALSSKLVSQQKEFFANIVVDAVMSLDELLP MNMIGMKKVQGGAIEDSQLVLGVAFKKTFSYAGFAMQPKKYHHPKIAILNIELELKAEKD NAEIRVDNVKEYQAVVDAEWTILYNKLEKIYQSGVKVVLSRLPIGDVATQYFADRDMFCA GRVQEEDLKRTMYACGGSIQTTVTNLSLGTCDLFEEKQIGGDRYNIFIGCPKAKTCTIIM RGGAEQFIEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIAGKEQLL IGAMAKALEIIPRQLCDNAGFDATNILNKLRQKHAGTWYGVDINNEDITDNLVACVWEPA VVKINALTAASEAACLILSVDETIKNPKA---------------KRNNVVPNAHFHKDWQ RYVKCWFNQPARKKRRRRKRIEKARKIAPRPLH-TLRPIVRCQTVQYNTRVRLGRGFTLE ELKRAGINKREARTIGISVDFRRKNRSVESLQHNVQRLKEYRSKLIIFPRKRGKPKKGDA TEEEMKMAKQVLGTVMPIKEAFKKERPRPITRKEKKFSAFMALRQARADVRLVGIRAKKA KEAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXLSCRYYEHKFPEIEDVVMVTVCQIADMGAYVKLLEYNGIEG MILLSELSRRRIRSINKLIRVGRNECVVVIRVDKDKGYIDLSKRRVSQEESSKCEEKFAK AKCVNSILRHVGELLHYQSDQELETLYQKTAWHFDKKYGKPGAAYDAFKRAVANPEIFDE CDLDPKTRSVLIDNIKQRLAPQSVKIRSDIDVSCYGYEGVDAVKNALRAGLNMSTENMPI KINLIAPPSYVVITQTLDRAEGMARGQQKIQAQQRNAAKQAALKADQKKAAQAALTHQCP VCKTKMPDPKTFKQHFESKHPKSPLPEELKNIMLGNLSTYMSRQGIMTVPKGHCAACAKP IIGQVITALGKIWHPEHFVCGHCKEPLGTRNFFERDDLPFCERDYHMLFSPRCAQCNGAI LDKCITALDKTWHPEHFVCAECGRQFGDAGFHEKDGKAYCREDYFNMFAPRCAGCNQPIM DNFISALNRQWHPECFVCYECHMPFGSTSFFDHEGYPYCETHYHAKRGSLCAGCHKPITG RCITAMYKKFHPEHFVCAFCLKQLNKGTFKEENDKPYCHPCFAKLFMRPLTDDETTAVFQ KLSRYIGENIRLLIERPDGLYCFRLNNERVYYCSEELLKRAANISRDNLINLGTCFGKFT KTRRFRLHITALDYLAPYAKYKVWVKPSAEQQFLYGQHVMKSGLGRITENTPQYQGVVVY SMNDLPLGFGVTAKSTAECRHVDPMTIVCFHQADIGEYVRNEETLADQRKFFVGGNWKMN GNKESIDGIIKFLNEGNPNTEVVCGPPTIYLDYVRQKLIGVAAQNCYKVEKGAFTGEISP AMIKDMGLNWVILGHSERRHVFGESDQLIGEKVAHALATGLHIIPCVGEKLEEREAGKTE EVVFRQMKASDWSRVVIAYEPVWAIGTGKTASPEQAQEVHVSIRKWLETNVSADVAKSTR ILYGGSVNAKNCKELAKKPDIDGFLVGGASLKPEFIDIINAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ELK ALKKKHEAFESDLAAHQDRVEQIAAIAQELNTLGYHDCASVNARCQRICDQWDVLGTLTQ QRRHALDEAEHILERIDQLHLEFAKRAAPFNNWMDGAKEDLVDMFIVHTTEEIQGLMDAH EQFKQTLGEADKEYNAIMALVHEIQRIAQQYGIQNAMENPYSTLQANDIAHKWREVQQLV PARDSTLQTEMIRQQNNERLRRQFASKANIVGQWIERHLDAVASVGMQKGKLEDHLNKLR GIEREVNAFRPNMDELEKYNEEVQEAMIFENKHTPYSMETLRVGWEQLLTSVARNINEVE NQILTRDSKGISNEQMEEFRKSFFHFDKSRTRRLEPKEFKACLISLGYNIRDDHQGEADF QRIMSIVDPNHLGYVTFDAFLDFMTREATDNDTAEQVMQSFRILAGDKPYITADILRREL PPDQAEYCIARMAPYTGLGAVPGALDYSSFSTALYGESDL-------------------- ------------------------------------------------------------ ---------FLSDCVGPEVEAACADPAPGSVILLENLRFHIEEEGKGVDAEGKKIKADPA KVEQFRASLKKLGDIYVNDAFGTAHRAHSSMIG-QHDIKAAGFLLKKELTYFAKALENPE RPFLAILGGAKVADKIPLIENMLDKVNEMIIGGGMAFTFLKVLNNMEIGKSLFDEEGAKI IHKLMDKAKANNVQIHLPVDFVTGDSFSADAKVGSATVESGIGANEMGLDVGPESNAKFT EVIGRAKTIVWNGPPGVFEFENFQKGTKAMMDAVVHATEKGATSIIGGGDTATCCAKFKT EDKVSHVSTGGGASLELLEGKVLPGVAALSDAXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXX------------------------------------------------ ------------------------------------------------------------ ------------AMAFDGINFQGQSLKIRRPKDYQPLPGMAEVPSVGVVSTVVQDSAHKI FIGGLPNYLNEDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYLDQACAGLNGMQLG DKKLIVQRASVGAKNAQVLPVQLQIPGLNMAQVTTEVLCLMNMVTPEDLEDEEEYEEILE DVKEECSKYGYVKSIEIPRPIKGVEVPGVGKIFVEFNSVIDCQKAQQALTGRKFSNRVVV TSYFDPD-------FLPMFDRVLVQRFAAETKTKGGVLIPEKAQSKVLNAKVVAVGCGAR NEKGETVPLQVKVGDQVLLPEFGGTKVVIDDEELHLFRESDILGKFERLKSQIPDIRTTL DIVKHMQSKKEPMQTHFQMSDNLYVAATIPPTDKVCLWLGANVMLEYNLDDAEALLKKNV AITSLEQVEEDLGFIRDQTTTIEVNMARVYNWDVKRRQ----XXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------PPIATQCFMLSNMFDPATTSLTWDTEIRDDVIEECNKHGGVLHIYVDKAS PQGNVYVKCPSIAAAVASVNALHGRFFAGKIITAAYVPLPNYHALL-------------- IEEKDEESPSPMQRPKQRNRRGAVSAEVYTEEDAASYVKKVVPKDYKTMAALSKAISKNV LFSHLDDNERSDIFDAMFPVHRHAGEVIIQQGDEGDNFYVIDQGEVDIYVNGEHVNSIGD GGSFGELALIYGTPRAATVKAKTDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLSKVSIL ENLDKWERLTIADSLEPVQFDDGQEIVKQGEPGEDFFIIVEGTASVLQKRAENEEPIEVG KLGVSDYFGEIALLLDRPRAATVVSRGPLKCVRLDRARFERVLGPCSDILKRNIAQYNSF VSLSVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------- ------------------------------------------------------------ -----------LAGCAMVLSRKKVNIACGLLFGIIALQTIAYSILWDLKFLLRNMALAGG VILLLAESKAEGRSLFAGLPSLGENTHKTYMQLSGRILLVFMFLTLLRFEFSLLQVIQNL IGTALVILIAIGYKTKLASLILVIWLTILNFYFNAWWNVPSYKPMRDFLKYDFFQTLSVV GGLLLVVALGPGGYSMDEHKKKW------------------------------------- --RNGICLKGIISSPLQTLNMQIRRELDLFANVVXIHSLPGIHTRHNNLDLVIIRESTEG EYSALEHESVPGVVESLKIITRVNSRRIAKFAFDYATKHGRKRVTAVHKANIMKLGDGLF LDTCKEVAALYPRIKFDSMIVDNCCMQLVSNPHQFDVMVMPNLYGNIIDNLAAGLVGGAG VVPGESYSADVAVFEPGARHAFASIVGRNQANPTAILLCAANMLRHINLPYYSHLIRAAV QKTIEAGKVRTRDLGGYGTLSDFTMAVINN------------------------------ ------------------------------------------------------------ --------------------------------------------------------KTPV QRTPLSATAHTHPVYCVNMVGTQNAHNLISVSNDGKMCSWSLDMLSQPQDSMELQHKQSR AAVMCFSFLSGDVNNFVVGTEETAVYTACRHGSKAGINDIFEGHQGPVTGIDCHAVPGQI DFSQYFITSSFDWSVKLWNIKENRPLHSFEDNNDYVYDTRWSPIHPALFATVDGMGQLDL WNLNNDTELPTATTVNVALNKCRWHQSGTSIAVGDDYGRVHIYDVGETLAQPKNDEWSKF VHTLQDLQTTKADQEEE-IQNQLLQATSIIEQQVDAELKRLDEMGEEDYEALRQKRLQQL KKAQKLKQEWLSQGHGQYEEIADEKEFFAVCKKSKNVICHFYRDSTFRCKIVDKHLALLA TKHIEARFVKLNAEKCKFLVDRLRIVVLPTICLTKDGKTVDYIVGFDDLGGKDDFPTEML EWRIARADVINYSGDLLTPP----------------XXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMS RKQTPSDFLKQIIGRPVVVKLNSGVDYRGVLACLDGYMNIALEQTEEYVNGQLKNKYGDV FIRGNNVLYISTQKRRI-------LLLRRQLAELNKHPVDGFSAGLIDDNDIYRWEVLII GPPDTYYEGGFFKTHLTFPRDYPLKPPKLKFITEIWHPNIDETGDVCISILHDPGEDKFG YERPEERWLPVHTVETIMVSVISMLADPNDESPANIDAAKEWRERREEFKKKVARCVRKS QETTVRQPNAVVKSNLMEFGRYVGECLPKYVQKVQVTYGNELEVMIHPDGIIPVVTFLRN HTHAQFLNITDIAGVDVPTRKYRFEIVYNFLSVAYNARIRVKTYTDELTPIQSIEPVFKG ANWYEREIWDMFGVFFANHPDLRRILTDYGFEGHPFRKDFPLSGYVEVRYDDEVKRVVVE PIEMAQEFRKFDYSTPWETFPNYRES---------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------AAGFDQEAAAVLMARIASFRAE TDDGPDVLRWLDRMLIRLCQKFGDYHKDDPNSFRFSEQLSLYPQFMFHLRRSQFLQVFNN SPDETSYYRHKLLIEDLTQSLIMIQPILYAYSFNGPPEPVLLDTSSIQPDRILLMDTFFQ ILIYHGDTIKQWKAAGYHELPEYENFRQLLQAPVNDAQEILQSRFPMPRYIETESGGSQA RFLLSKVNPSQTHNNMYAEGGGHVLTDDVSLQVFMEHLKKLAVSSSSXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXKLYTGLREVVTDHLVNKVKEDVLKSLNNNFLQTLNIAWNDHQTSM VMIRDILMYMDRVYVQQNNVDNVYNLGLMIFRDKVVRCSTIRTHLRDTLLDMVAKERRGE VVDRGPVKNACQMLMILGIGSRSVYEEDFEHPFLEKSAEFYRLESEKFLQENSASVYIKK VEARITDQSESAV----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------DIINVFPSRMAMTLMKAKLK GAQKGHSLLKKKADALRIRFRTVLKKIIETKSLMGDVMKEAAFSLAEAKFAMGDFNDLVI QNVSKAQIKVKSKKDNVAGVLLPIFEHYQDGSDSYELTGLSRGGQQIDKLKRNYAKAVEL LVELASLQTSFVTLDETIKVTQRRVNAIEYVIIPKIERTLSYILQELDEREREEFFRLKK VQGKKQRDKPANILDDYDEDMLFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSNAGVLMVGPNFRVGKKIGCGNFG ELRLGKNLYNNEHVAIKLEPMKSRAPQLHLEYRFYKQLGQAEGIPQVYYFGPCGKYNALV LELLGPSLEDLFDICDRRFTLKTVIMLAIQLITRMEYVHSKHLIYRDVKPENFLIGRQSN KKQHIIHIIDFGLAKEYIDSETHKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEAL GHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATAIEVLCENFPEELATYLRYVRRLD FFETP------------------------------------------------------- ------------------MTTIRPFTCDDMFRFHNVNLDPLTETYGLPFYMQYLAHWPEY FQVAESPSGEIMGYIMGKAEGHSENWHGHVTAVSVAPDFRRLGLAAKLMNILEEISEKKH CLFVDLFVRVSNQVAVEMYKRLGYSVYRRVLDYYSGEEDEDAFDMRKALSRDVHKQSVIP LPHPVRPEELEQQLDCALDLMRRLPPQQIEKNLGDLIDLVPSLCEDLLSSVDQPLKIARD NTVGKDYLLCDYNRDGDSYRSPWSNQYDPPLDDGTVPSDRLRKLEIDANTAFDQYREMYF EGGVSSVYLWDLDHGFAGVILIKKAGDGSKKIRGCWDSIHVVEVQEKSSGRSAHYKLTST AMLWLQTNKAGSGKMNLGGSLTRQQETDANVSESNPHIANIGRLVEEMENKIRSTMNHIY FGKTKDIVNGLRQTEALQRETLRNDLAAALKHRSQMDADFDPVDEPLDEVQKQPTIEVVP QSEKVDPDKRMTTPYLTKYERARVLGTRALQIAMCAPVMVELEGETDPLAIAMKELKARK IPLIIRRYLPDGSYEEWAIDELIITEKRLTLKERAMAPAGDGAFTIGKGVLAGASAVGLG MLCYYGLGMSNQVGAIDRAAIWPDVVRQRIRDTYMYFGGSLIFTAVSRSPVMMRLVMRNG WLTIIGTMAAMIGSGMVVRSLPYKEGSKQIAWMVHSGIVGAVIAPLTLLGGPLMIRAACY TAGVVGGLSALAMCAPSDKFLYMGGPLAMGLGVVIVSSLGGMFIPPTTALGAGMYSVALY GGLALFGMFLLYDTQKIIYRAENHPVYALQPYDPVNNSVGIYLDTINIFIRIATILAGGG NRRRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXWEDKLARVGPIA KPMATRKLAKKIYKITKKALRKGVRDIPKYLRKGEKGLIVIAGDTTPVEIVCHMPLLCEE SDIPYCYVPSKDDLGSACGSHHPTAMIMIKPHENYQELYDTVKEEMKALPLPI---ENLE EQGLVKNPNLEVAQWKFLLGTDRHRNDQKLKNDLLQVIKENDMAPFYEIVCADLGWPVDQ ALLEKMKDANLAKLKELDDAVEDAEQNLGETEVRDFMLKKAEYLSKIGDKDGALSQFRKT GEKTVTLGFRLDMVFHQIRLGLFFMDHDLIKRNLEKAQSLIDEGGDWDRRNRLKVYRGVY SMSIRDFKTAADLYLDTVATFTSYELMDYKQFVTYTVLCSMIALERPKLREKVIHGSEIL EVLHSLPDIKEYLFSLYNCQYSDFFKSLAVMEQRMKHDRYLAPHYRYYTREMRIHAYSQL LVSYQSLTLDYMAKAFGVTPDFIDQELSRFIAAGRLHCKIDKVGGIVETNRPDSKNYQYQ ETIKKGDILLNRIQKLSRVINI-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------AGKVPPAKILIIGGGVAGLAAAGTARNXGAIVRLFDTREAVKE QAQSMGAEFLEVDIKESGEGAGGYGKEMSKEYIEAEMALFAKQCKEVDIVISTALIPGKK APLLITKEMIESMKPGSVVVDLAAESGGNIETTKPGELYRYHDVTHIGYTDLPSRLPTQS STLWSNNISKLLLSFGFDVDLNDDVCRGCIILNKGEMMWPPPKKEEPNYFQNTLKDAFMY TTGLAGMLGLGMVSPNPAFTTMVTTFGLAGIVGYHTVWGVTPAL---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --MVAPSSAANCPPGLEYLTQIDQLLINEQVEMLKASPSFKTNRNYEIKNSTGQIVYFAA EDTCYSTQNLCSNGRPFEVKICDTTGREVIHLDSPVTS--ESCCNLSPLKKVEVQAPPGQ TIGYVRQAVYKPKFKIMNAVLVIDGPGFTCN--LF-GDVEFQVYATHVGQICKQWSGLVK EMFIDANNFGVTFPLDLDLKLKATLLGAVFLIDFLISENKRH----ELQQFLQLEQQRAL FHSQIHRLMDLCWDQCVDKMRDKMDSKTETCFTNCVERFVDTSLLITNRFQQMLQRGL-- --EGLVQRRNVAHEEEDLDSKETRLTLMEEVLLLGLKDREGYTSFWNDCISSGLRGCILT ELALRGRLELEKTGMRRRSLLNRKVICKSDTPTGDVLLDEALKHIKETNPPETTQSWIEY LSGETWNPLKLKYQLRNVRERLAKNLVEKGVCSTEKQNFLLFDMTTHPLTDNQIKSKLVK RVQDSVLSRWVNDPHRMDKRMLALIYLAHASDVLENAFAPLSDDDYEVAMKRVRELLDLD FEQETMKEGANELMWAVIAAFSKAKKLTEVNEENCEVCVKFLTRFMDSLDKIEDEFRKYC KGTKKAENRFCYYIGGLEESATGMLSEMSKPISWGMPPDKVCMKIYRKDEQICDLKYEKS IDFATVDLKKLKVKDLKKILEDWDTTCRGCSEKSEFIQLIEDLMPQYAPEAAXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXMPKVVSRSVVCTDTKDQEEYQGEKPLYVYYCLCGQMSLILDCPLE KLPLRKTDNARVIDSNKHAHKLTCEPDETVYLKRPNGIEKQYRQKCKKCGLWLYYRHRNQ ITFIIDGALKQESQVTDIIKQDIVAPKKVMVKKHTKNMGKFSSVTVSTVDEEEDEIEAKE IADSYAANAKVIEKQLWRKGLSKRKLMEQAEEEAKRSRPKGTLIDLTRQCMRVAASQQIR SYADMSFTFASPGSVNVKQVDVPSFSGSFGILPNHVPTLAVLKPGVITVIEEDGTQKKYF VSSGTISINDDSSVQILAEETARLEELDAEAIRDGANKAAQDLTTEQAKAEAQIAIECYE ALQKAL-CKYFATELISRLKET-DTKEIIRTGHGLDKKKEFPYKYSELRLTEALLEPHIC DRILEYNVHAERKGSLRYAKGRSETMSTLHGLVEKGVKVELGIPYELWDTPSAEVTKMQR KCFKLAEDYEEDIEDWYYNHQTDFTKFLCADRYLKGKDQ-FSPMDVTSEEDVMKAMLAKK QFGGLHVAVNCAGVGVAVVTYNAKKNRVHKLEEFQRVINVNLVGTFNVIRLAAQLMNENE PNADGQRGVIVNTASVAAFDGQRGQAAYSASKGGIVGMTLPIARDLAHIGIRVNTIAPGL FDTPLLGELPEKVRKFLATSVPFPQKLGVPDEFAHLAQFIVENPMMNGEVVRLDGGIR-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------AHIFAGVD VHHEPIPVIPTVHYNMGGIPTNYTGQVIQTDGVDKEVPGLWAAGESACVSVHGANRLGAN SLLDLVVFGRACANNIARRFKPGDKLPDLSPNAGEESVANIDKLRHANGSTTTADLRLRM QKTMQNYAAVFRDGPTLQEGCKRLSKLYEELDLKLSDRGMVWNSDLIESLELQNLMLNSV QTAVAAENRKESRGAHAREDFKKREDEYDYTKPLEGQKPRPFDKHWRKHSLTHVDPSTGK VSISYRPVIDKVLDSSKIETVPPKVRSY-------------------------------- ------------------------------------------------------------ ----LCQENAWLRDELANTQQKLQQSEQKVATLEEEKKHLEFMNQMKKYDMEGSLGFPDD DEDQQQSAMAQAASGGYEIPARLRTLHNLVIQYASSGRYEVAVPLCKQALEDLEKSSGHD HPDVATMLNILALVYRDQGKYKEAGNLLHDAMRIREKTLGNDHPAVAATLNNLAVLYGKR GKYREAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEQY--------- -----------------------------KIAARYDAETEREVLGWFKQLLGPGMREVEK QLRNGQDLVRLAAKIKAKKMTLKPNTMSAPFKQMENIQIFLNFCENYGVPKTGLFQTVDL YEGRNMAQFLSSICMLGTEAQRHGFNGPTIGPKPTEKNIREFSEEQLRAGQLQAGTNKCA SQSIGGVRHIADIRADDMDKKGQAIIGLQAGNKGASQSGMMIGGVRHVADIRADDMSKDS EAVIGLQAGSNKGASQSGMAIGGIRHVADIRADDMDKEGQAIIGLQAGSNKGASQSGMAI GGVRHCADIRADDASEGQAVIGLQAGSNKGASQSGMAIGGVRHCADIRADDAEGQAVIGL QAGSNKGASQSGMTFGGARHAADIRADDMSSAGVINLQMGTNQGASQSGMSMGGRRDIMP EVYSFGSDPITCHAWNADRTQLALPNNNEVHIYQFVWNKQHVLDEHVQNVTGIDWASNSN RIVTCSADRSAYVWATMVILRINRAATCVKWSPLENKFAVGSGARLTSVCYFDPDNDWWV SKHIKKTIRSTITCLDWHPNNVLLATGSSDFKTRVYSAYIKEVEAKPTPTSWGSKMPFGN LMADFHYSAGWVHNVSFSASGDCLVWVGHDASISIVDATLKTTFLPFVTCMWVTENTFVA AGHDCYPVMYQYDASKIIFINKLDQLKFSAMREFQSRDRRAQSLPSVHQNTITQLSIHTG SKSNCSKLTTTGIDGQLVNWD-------YVGFVNLPNQVYRKAVKRGFDFTLMVVGESGL GKSTLINSMFLTDLYNNEYPGPSHRVKKTIQVETTQVVLKEGGVQLKLTVVDTPGFGDAV DNSNCWQPIIDHIET--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------MSRRYDTRTTIFSPEGRLYQVE YAMEAIGHAGTCLGILAKDGVILAAEKRNTNKLLDEVSYSEKIYKLYDDMACSVAGITSD ANVLTNELRLIAQRYMLQYQEPIPCEQLVSQLCDIKQLYTQFGGKRPFGVSLLYMGWDKH YGFQLYQSDPSGNYGGWKATCIGNNSGAAVSMLKQEYKESEVDLQTGLELAIKVLGKTLD TNKLTPEKVEIATLTRENGKTKIQIVADSQLEALIKKCEEEEAKIEAEKKK--------- ------------------------------------------------------------ -----------------------------DDIENKQHEINRSWERLRAKASERRSRLEDS YYLHRFLSDYRDLILWISELKSIISADELAKDVAGAEALLERHQEHKGEIDAREDSFRAT ADAGQKLLDSDHYAVEEVKNKLVTLATEKTNLLELWEQRRILYEQCMDLQLFLRDTEQAD AWMTKQEAFLSNDDLGDSLDEVEALIKKHEDFEKSLAAQEEKIRALDEFATKLIENDHYA ADEVAARREALLQRRAALYKRAEARRIQLEDSYKYQMFERDCDETKIWINEKLKATSDEG YLDPTNLQGKLQKHENFCAEVSANEAQVEAVTKSGQELIDSNHYASDRIRERLEEIHNIW QQLKEQSERKGAKLKEASEQQQFNRNIEDIEVWISEIEGQLMSEDYGKDLTSVQNLQKKH ALLEADVSSRQERIDNIIQAADQFVQQGHFDSETIKAKQVQLVERYRALQEPM------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ESLAYQQFAANVEEEEAWITEKQHLLAGDDLGDSLAAVQGLLKKHEAFETD FSLHRERCNEINKEGEKLIEEGNHNADNIRQRCETLHKNFEALLDAANRRKANLIDNSAF LQFIWKTDVVESWIADKETQIRSEDYGRDLSSVQTLLTKQETFDAGLQAFEKEGIQTITA LKDQLIASNHAQTPAIEKRYNDVITRWQRLLTDSEDRKQRLLRLQEQYRQVEDLYLSFAK KASAFNSWFENAEEDLTDPVRCNSVEEIKALREAHEQFKASLKTAEEDFNQLAALDQQIR SFNVGP------------------------------------------------AANQFH QWLTETRSAMMEGSGTLESQLEATKRKAAEVRAQRSQLKHIEDLSAAMEERLILDNRYTE HSTVGLAQQWDQLDQLGMRMQHNLEQQIQACNQSGVSEDALREFSMMFKHFDKDKTGRLN HQEFKSCLRALGYDLPMVEEGQVDPEFEAILDVVDPNRDGIVTLQEYMAFMISRETENVQ SSQDVEAAFRALAAGERPYITGNELYSNLTKEQADYCISKMKPYEDPRGRVI-------- --------GIQCYQCDSNEDYSCPSYRIFDRNINALVDCNSFEAKTPGTFCMKITQQSPG WGAWKKVTRRCGSRSESGVAWGCQWDFEENGVWREVCYCEDRDGCNGAS-IDKDDVENPQ LVSEYVNDIYDYMRELESRQINSRMRGILIDWLVQVHLRFHLLQETLYLTVAIIDRFLQV TVARNKLQLIGVTSMLIASKYEEMYA---------------------------------- ----------------QVDATQHTMAKYFMELTITDYEMVSVPPSKIAAAALCLSMKVLK WNDTLQYYSKYNEEDLRPTMERIALLVTKKLTAIKAKYQSSKFMRISLVPELSCDLIQEM AXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------LCLKYFIEAGAMAVR RCKKTDLKRIAKATGGKLIVTLANLEGEASYDASLLGQAEEVVQERICDDELILIKGPKA RSCASLILRGANDFMVDEMERSIHDALCVVKRVLESKTVVPGGGAVEAALSIYLENFATL LSSREQLAIAEFARSLLVIPKQLAVNAAQDSTDLVAKLRAFHNTSQLKPEHKELKWIGLD LYEGQVRDNRKAGVFEPAISKIKSLKFATEAAITILRIDDMIKLAPEDKRGRSYSDAVRE GTLDDDEARLLVSKNILNNFLVEGKDLTIEYNIYNVGGSSALDVHLHDGSFMPGDFENVA GSLDVKWERLAPGSNVSHVVVLRPLKPGYYNFSSAEVTYLASDTERKFGYTSAPGEYGIV NFKDYDRKFSPHVLDWAAFAVMTLPSLGIPFLLWYGSKSKYEQLKPKKN----------- -----DVAEGLKIFSETLVNENVSLVISRQILSEFTNKLSSLPDDVAKEVCHFTLDKIQP RVISFEEQVASIRQHLASIYEREQKWKESAKILVGIPLETAQKQYSNDYKLDTYLKIARL YLEDEDPVQAEAYINRASMLQADSQDVKLQIYYKVGYARVLDFRRKFIEAAQRYNELSYK TLIAEEERLMALRNALVCTILASAGQQRSRMLATLFKDERCQQLPAYGILEKMYLDRIIK GNELQEFAELLQPHQKAVTADGSTILDRAVVEHNLLSASKLYNNISFDELGSLLEIPPAK AEKIASQMISEGRMNGYVDQIDSIVHFEAREALPNWDKQIQNLCYQMNGTIEKIAAAAPE WMSKTVEEQMN--LTDVVLRNFRVAKVFRENTDRINSLDFSPNGETLISSSDDDSIVIYD CQNGTPKRTLNSXKYGVDLISYTHAINTAVHSVKKV-------SVLDFKTSQYVAVHSKV IRDMCVSEQEDVLLSASIDKTVKVTSLSSNTVIQTYSLPA-PVCAWDKDNPVFYAGMQNG VVHVYDTRN--------------------------------------------------- ------------------------------------------------------------ ------------------------KYILTEKRGEKQNVAVIQLNRPKALNALCNDLMLEV NQALDQFEADSSIACIILTGSEKAFAAGADIKEMQNKEFSEIYNTNFLSHWNRVSLTKKP VIAVVNGYALGGGCELAMMCDIIYAGDKAQFGQPEISIGTIPGAGGTQRLTKAIGKSKTM EMVLTGNRISAQEAEKAGLVSKVFPADVVMDEAVKIAEKIGTHSPIIVKMAKEAVNASFE VSLNEGLHFEKRMFHQTFATNDRREGMTAFVEKRPPKFTD >Amynthas_koreanus XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----RQLQTSSVRRDIDQAAKYIGAGAATV GVAGSGAGIGSVFGSLVIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLILFAFX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------- ---------AISMLAVINCADNTGAKNLYIISVHGIRGRLNRLPAAGCGDMVMATVKKGK PDLRKKVMPAVVIRQRKTIRRKDGLFIYFEDNAGVIVNNXGEMKGSAITGPVAKECADLW PRIASNA--------------------------AHIFASFNDTFVHVTDLSGKETLVRVT GGMKVKADRDESSPYAAMLAAQDVAERCKQLGITALHIKVRATGGNRTKTPGPGAQSALR ALARAGMKIGRIEDVTPIPSDSTRRKGGRRGRRLXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPRI GLVRSKTYSTPRRPFEKERLDQESKLIGEFGLRNKREVWRVKYTLTKIRTAARELLTLDE KDQRRLFEGNALLRRLVRIGVLEESKMKLDYVLGLRLEDFLERRLQTQVLKLGLAKSIHH ARVLIRQRHIRVRKQVVNLPSFVVRLDSQKHIDFALTSPYGGGRAGRAKRKNQRKAAGGG DAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRMHAPGKGISQSALPYRRSVP TWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQTRYVSGNKILRILKAKGLATT IPEDLYYLIKKAVAIRKHLERNRKDTDSKFRLILVESRIHRLARYYKTRKVLPPVWKYES STASALVAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXX-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------LVKVWNLTNCKLXTNHYGHTGFLNTVTVSPDGSLCASGGKDSQAMLWD LNEGKHLYTLDGGDTINALCFSPNRYWLCAATGPSIKIWDLEGKVVVDELKPEVMSSS-K SPDCLSLAWSADGQTLFAGYSDKLIRVWQVSMAARXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXMSDAEGDDVAAPASSTGHMDLNTAIQEVLKTALIHDGLARGLHEC TKALDKRQAHLCVLANNCDEQNYVRLIEALCAEHGINLIKVESNKKLGEWVGLCKLDKEG KARKVVGCSCVVVKDYGKESQALDVLNEYFKTRKXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------ ------------------------------------------------------------ ---------------------------------------------------------LSI VPVRRGYWGNKIGKPHTVPCKVTGRCGSVLVRLIPAPRGTGIVSAPVPKKLLHMAGIDDC YTSASGQTATLGNFAMATYHAIANTYCYXTPDLWKETVFVKSPYQEHTDYLMKXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXMKFNKYVSSSSRKNRQRHFNAPSHIRRKIMSSPLSKELRQKYNVRSIPIRKDD EVQVVRGHHXGQQVGKVVQVYRKKYVIHIERIXREKXNGTTSYVGIHPSKVVIVKLKMDK DRKSILERKAASRQKGKHTEESVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XAKRTKKVGIVGKYGTRYGASLRKDIKKMEXTQHSKYTCSFCGKETMKRKAVGIWSCKSC KKIVAGGAYVYSTTAAVTVRSTIRRLKET--------------KNKPYPKSRFCRGVPDA KIRIFDLGRKRARVDEFPXCVHLVSXEFEQISSEALEXGRIXANKYLVKHCGKDAFHLRV RLHPFHIIRINKMLSCAGADRLQTGMRGAFGKXQGTVARVDIGQVIMSVRVKDXHKEKVI EALRRAKFKYPGRQKIXXXRKWGFTKWEREKYEXLRAEGKLITDGVGVQYKPDHGPLAAW KALQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXCIQCYQCDSNEDRSCPSDRHFDRNLNALIDCNSFEAKIPGTFCMKITQQSPG WGSWMKVTRRCGSRSDTGVAWGCRWNYEENGVWRETCYCEARDGCNGASFXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXEEEDARLLVAKNILNQYLVEGKDLTVEYSLYNVGGSAAVSVELQDDSFPEDSFEVVA GNLDAKWERIAPGSNMSHVVILKPLRSGYFNFTSAQVTYKPSEDEAQFGYTSNPGEGGIV NFRDYDRKFSPHVLDWAAFAVMTLPSLGIPFLLWYSS------------XXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX >Bugula_neritina MTERKAVIKNADMAEDMQQDAVDCATTALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSG-------FHTTNIRQDIDQAAKYIGAGAATV GVAGSGAGIGTVFGNLVIGYARNPGCKQQLFTYAILGFALSEAMGLFCLMMAFLMLFAFM ----KDGKGAAPTAHRIRITLTSRNVKSLEKVCADLIKGAKEKXLKVKGPVRMPTKTLRI TTRKTPCGEGSKTWDRFQMKIHKRLIDLVSPSEIVKQITSISIEPGVEVEVTIADMDQIT QFVEPLKEFSKDSIRLVKRCTKPDRKEFQKIAVATAIGFAIMGFIGFFVKLIHIPINNII V---QVSKKRKFVNDGVFKAELNEFLTRELAEDGYSGVEVRVTPTRTEIIIMATRTQSVL GEKGRRIRELTAVVQKRFNFPEGSVELYAEKVNNRGLCAIAQCESLRYKLLGGLAVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKAMKFVDGLMIHSGEPSREYVDTAVRHVLLRQ GVLGIKVKIMLPWDQTGKMGPKKPLPDNVSIVEPKDENLPATPYSESKQAPMSKRGRGGS AGGKFRIALGLPVGAVMNCADNSGAKNLYIIAVFGIKSCLNRLPAAGSGDMVLATVKKGN QSLXKKVMPAVVIRQRKCIRRKQGVFVYFEDNAGVI------------------------ ----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGKPRGIRTARKQRNHRRDQKWHDKD YKKXHLGTRWKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP NDGCLNFVEENDEVLVSGFGRSGHAVGDIPGVRFKIVKVANVSLLALFKGKKERPRSXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPRL KTVHSKTSATPRRPFEKERLDQELKIIGEYGLKNKREVWRVKLVLAKIRKAARTLLTLEE KDPKRLLEGNALLRRLVRIGVLDESKMKLDYVLGLKIEDFLERRLQTQVFKLGLAKSIHH ARVLIRQRHIRVRKQLVNIPSYIVRLDSQKHIDFSLKSPYGGGRPGRVKRKKNRKAAAG- --MGNIIDSL-KALFGKKDMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERATEAKEELKRMLDEDELRD AVLLVFANKQDLPNAMSPSEITEKLGLQSLRNRSWYIQATCATNGEGLYEGLDWLSNQLK NVKMPLAKDLLHPTYDEEXRKCKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRKKAHMVRMNVLADALKSISNAEKRGKRQVLLRPSSKV IIRFLKVMMKHGYIGEFEIVDDHRSGKIVVNLTGRLNKCGVISPRYDVGISDIETWTNNL LPSRQFGYVVMTTSQGIMD-------------------GRMHAPGKGISQSALPYRRSVP TWLKLTSDDVKEQIFKLAKKGLTPSQIGVILRDSHGVAQVRFVTGSKILRILKAKSLAPA IPEDLYHLVKKAVSIRRHLERNRKDRDAKFRLILVESRIHRLARYYKRTRVLPPTWKYES STASALVAVVEIPEVKLFGKWSTDEVQVGDISLQDYIACKDKFSKYLPHSAGRFSVKRFR KAQCPIVERLACSLMMHGRNNGKKLMTVRIVKHAFEIIHLLTGENPLQVLVNAIINSGPR EDSTRIGRQGTVRRQAVDVSPMRRVNQALWLLCTGAREASFRNIKTIAECLADELINAAK GSSNSYAIKKKDELERVAKGNR-------------------------------------- ------------------------------------------------------------ ----------------------------------------------------------NT ANPIIVSAGWDRIVKVWNLTNCKLKTDHFGHTGFVNTVAVSPDGSLCASGGKDGQAMLWD LNEGKHLYTLDAGEPINAMCFSPNRYWLCAASGSQVKIWDLEGKLIVDELTPAVHSTS-- -----------------------------------MREYKLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKQVEVDGSQCMLEILDTAGTEQFTAMRDLYMKNGQGFILVYSIT AQSTFNDLTDLKEQILRVKDASDVPMVVVGNKCDLEDERVVGKLANEWRIKFMETSAKKK IGVNEIFFDLVRQINRKQPDT----KP-NTDHVNLRVSNQDGSSVTFKIKKHASLKKLMN AYCAREGIDMNAVKFRFDGVPLNPEDTAADLNMEDDDTIDVFQNQTGGXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMANIRKKLVIVGDGACGKTCLLIVFS KDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTHVILMCFSI DSPDSLENIPEKWTPEVRHFCPNVPIILVGNKKDLRNDPNIISDLKKMKQEPVKTEQGRA MADSINAFGYLECSARNKEGVREVFETATRAALQVKGHKKKKMEDFQSAEETAFVVDEVS NIIKEAIEGAIGGNAYQHNKVNQWTSNVVEQCLNQLTKLGKPFKYIVTCVIMQKNGAGLH TASSCFWDNTTDGSCTVRWENKTMYCIVSVFGLSI-----SKIVKPPGEKHDEFEMSVSQ ALLELEMNSDLKAPLRELHIRGAKECDFNGRKVVIIFVPVPQLRQYQKIQVRLIRELEKX FSGKHVVFIAQRRILPKPKPKVVSKYKQKRPYSRTLTSVHNAILDDLCYPAEIVGKRTKV RLDGSHLIKVHLDKNQQTNVEHKLDTFSAVYKKLCGKEVVFEFPEYMLPAGEFRGGFGGR GRGRGRGRGRNKDGDKEWVPATKLGRLVKDMKIKSLEEIYLFSLPVKEFEIIDYFLGSTL KDEVLKIMPVQKQTTAGQRTRFKAIVALGDFHGHVGLGVKCSKEVATAIRGAIILGKLSI VPVRRGYWGNKLGAPHTIPCKVTGKCGSSSMRLIPAPRGTGIVAAPVPKKLLTMAGIEDV YTQSVGATSTLGNFAKATFFAIAKTYSFLTPDLWKETVFTKSPYEEFTDYLAKMSGNSDA LSLKEEDVKKILACGSHIGTSQVDFQMEQYMYKRRPDGVYIMNMRKMWEKMVLAARAIAA IENPADVFVVSSRPYGQRAILKYAAATGAVAIAGRFTPGTFTNYIQKNFREPRLLVITDP RADHQAVREASYVNIPVIALCNSDTPLRFVDIAVPTNNKSIHSIGLAWWFLAREVLRLRG TISREVPWEVMVDLYFYRDPEEVEKEEPVQDWAAEVAVAPAVT-YDDWSTAPTEDWSAPA PGDQWGGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXX---SNTKVGSTVRQRKPASGGXGGAGMWKFYSEDSPG IKVGPVPVLVMSLLFIASVFVLHIWGKYTR-KKGDKKKSAMNEVVTREYTINMHKRIHGM GFKKRAPRAIKEIRKFAHKTMGTSDVRIDSRLNKHVWSCGIRNVPYRLRVRLARKRNEDE DSAEKLYTLVTYVPVATFKNLSTVTVD-----------KYRLVRKIGXGSFGDIYLGINN QSGEEVAVKLESHKARHPQLLYESKLYKILQGGVGIPHIRWYGEKDYNCLVMDLLGPSLE DLFNFCSRRFTMKTVLMLADQMIGRIEYVHNKNFIHRDIKPDNFLMGIGRHCNKVFLIDF GLAKKYRDNRTRQHIVYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRGS LPWQGLKAATKNXKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMY-- -LFRILFRTLXHQYDYTFDWTMLKTKAAA-MNPEKLKARTGGKGSVRRKKKVIHRTAATD DKKLQTSLKKLGVNNIPGIEEVNMIKEDGTVIHFTNPKVQASLVANTFSITGHAETKQIT EMLPGILNQLGPENLASLKKLATATTEVD-EDDEV--------------MTRYSSEPDNA AKAAKAKGXHLRVHFKNTREAANAIKHMHLRK---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -KTEIREAFDLFDVDGSGTIDAKELKVAMRALGFEPKKXEIKKMIADIDKEGSGTIDFND FLTLMTQKMGEKNSKEEILKAFRLFD-DHNWKISFKNLKRVAK----NLTRTEMRSADQD SDGLASEAEF----------MGISRDKWHKRRKTGGRQTQLRGKRKFEMGRAPANTKLGH KRIHTVRTMGGNIKLRALRLDTGNFAWASEGISHKSRIIDVVYNATNNEMVRTKTLTKNT IVQIDAAPFRQWYEAHYAKPLGRKKQAKYTEEEKAELPKRSHKTQKKYDERQKTAFVDPA VEEQFVAGKLYACISSRPGKCGRSDGYILEGQELQFYVRKLR-----MALLLPEKFQHIL RIFNTNIDGNICILYALTSIKGIGRRYAYAVLRKADIDIRKRAGELSEEEVQQVITVMSN PRQYKIPDWFLNRQRDIKDGKTSQVIANVLDNKMREDMERMKKIRLHRGLRHYWGLRVRG QHTKTTGRRGRTVGVSKKKDANTDSDS---------SAEAGTQPGEAGKGGKQSRSEKKS RKAMSKLGLKPIAGVSRVTVRKSKNILFVIIKPDVYKSPASDTYIVFGEAKIEDLNQQAQ IDAAEKFKAEEEVDEGGVEAKDIELVMSQAGVSRAKAIKALKSNNNDIVNAIMMGRVRTK TVKKASRVIIEKYYTRLTTDFHTNKRICEEIAIIPSKPLRNKIAGFVTHLMKRIQRGPVR GISIKLQEEERERRDNYVPEVSHIEEIDAETKDMLKMLDFGTMPGLQVT------MKFKF KEELSFDVRAKESAKIRAKYPDRIPVIVEKAPNSQIQDIDKXKFLVPSDISVAQFMWIIR RRIQLAAEKAIFLFIKNVLPQSSASMGQIYQEHKDDDGFLYIAYSGENTFGMKELRIRKL CLNICVGESGDRLTRAAKVLEQLTGQQPVFSKARYTVRTFGIRRNEKIAVHCTVRG---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------LREAFYRQNLPNLFNLMSTILVFAVVIYFQGFR VDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAAKFSGNFLVNLLG TWADSGAGG-ARSYPIGGLCYYMSPPETFSHVMIDPLHAILYIAFMLGSCAFFSKTWIDV SGSSAKDVAKQLKDQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVVADFLGAIG SGTGILLAVTIIYQYFEIFVKEQSEQGGMSTLLFQVERAFQKQGNVNLNKKSLLMPRWYK NIGLGFKTPREAILGTYIDKKCPFTGPVNIRGRILTGVVKKMKMQRTIVIRRDYLHFVKK YRRFEKRHKNLSVHISPCFRDVSVGDVVTVGECRPLSKTVRFNVIKVAKSASSKKSFKKF MVNVPKTRRTFCKGRNCKKHTAHKVTQYKXGKDSVYAQGKRRYDRKQQGYGGQTKQVFHK KXKTTKKIVLKMECSTCKYKKQLAIKRCKHFELGGDKKKKGQ----MGRVIRAQRKGAGG IFKSRTRTRKGPAKLRALDYAERHGYLKGVVKDIIHDPGRGAPLAKVSFRDPYRYKKRSE LFIAAEGMHTGQFLYCGKKATLQIGNILPIGQMPEGTMVCNLEEKTGDRGALARTSGNYA IVVSHNPETGRTRVKLPSGNKKLVPSANRAMVGIVAGGGRIDKPLLKAGRAYHKYKVKRN SWPKVRGVCMNPVEHPHGGGNHQHIGKASTVSRFKSHGRKVGLIAARRTGRLRGTR---- -------------------------VKKMEIAQHSKYTCSFCGKETMKRTCVGIWACRAC KKAVAGGAYEYSTAAAATVRSAVRRLREMQEMGRRPARCYRYCKNKPYPKSRFCRGVPDP KIRIYDLGRKKARVDDFPLCIHLVSDELEQLSSEALEAGRICCNKYLVKNIGKDSFHIRV RVHPFHVLRINKMLSCAGADRLQTGMRGAYGKPLGTCARVSIGQPIMSVRIRDQHKDAAI EALRRSKFKFPGRQKIFVSTKWGFTKWEREDYEEMRSKGRLVPDGVGVQYRREHGPLSAW KKDQKVIKVLGRTGSQGQCTQVRVEFLDESNRSIIRNVKGPVREGDILTLLETEREARR- -----TTSFGKRKNKTHTICRRCGRSSFHIQKSLCAQCGYPYAKTRHYNWSEKGRRRKAT GTGRMRHLKIVQRRFKNGFREGTTPKPRKAMSDDKSSAKELDQWIEQLYECKQLTESQVK TLCEKAKEILMKESNVQEVRCPVTVCGDVHGQFHDLMELFKIGGKSPDTNYLFMGDYVDR GYYSVETVTLLVALKVRHYERVTITRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDSQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHSNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRC GNQAAIMELDDSLKYSFLQFDPAPRRGEPHVTRRTPDYFLMGAYRYVSELWRKXQSDVMR FLLRVRSWQYRQLNVVHRVPKSTRPDRARRLGYKSKQGYAIFRIRVRRGGRKRPVPKGQT MGKPTNQGVNQLKNQRSHQAIAEERVGRKCGALRVLNSYWVAQDSTFKFYEVICIDPFHK AIRRNPDTQWITKPVMKHREMRGLTSANKKSRGLGKGRRYNKTNGGSRWASW-------- ----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----KMLNYINYRMRCTL QDGRTFIGTFKAFDKHMNLILGDCDEFRRIKPK--KSREEKRVLGLVLLRGEHLVSMTVE GPPPVEEGQSRVPIPGAPGG-GMGRAAGRGVGPGGGLQGPVRGVGGPSQQSMAPQ----- ----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSEGIKQYYVGKIEELQLTVTEKTQN LRRLEAQRNELNAKVRMLREELQHLQEQGSYVGEVVKPMDKXKVLVKVNPEGKFVVDLDK NIDMNDVVANARVALRNDSYTLHKILPSKIDPLVSLMMVEKCXDSTYEMVGGLDKQIKE- KEVIELPVKHPELFDALGIAQPKGXLLYGPPGTGKXLLARAVAHHTECTFIRVSGSELVQ KFIGEGSRMVRELFVMAREHSPSIIFMDEIDSIGSSRLEGSSGGDSEVQRTMLELLNQLD GFEPKQNIKVIMATNRIDILDSALLRPGRIDRKIEFPAPNEEARADILKIHSRKMNLTRG INLRKISEMMPGA----------------------------------------------- -----LSFMENFGLSGAAAIISKTASAPIERVKLLVQNQDEMIKQGRLETPYKGVVDCTL RTFRTEGVLPFWRGNLANCIRYFPTQALNFAFKDSIKKMFNPKKSDSYTLKFSKNIASGG TAGALSLCFVYSLDYARTRLANDAKSAGKRQFNGLVDVYRKTLKSDGIQGLYRGFVISCV GIIVYRGFYFGLFDTLKPMLLKDDASFFLSFALGWVVTVSSGLLSYPIDTIRRRMMMTSG QAVKYKGSIDCGLQIVKNEGFMSLMKGAGANILRGVAGAGVLAGFDKFQALYIKWRLMGD CGDLDRQIEQLRRCEIIKESEVKALCGKAREILVEESNVQRVDSPVTVCGDIHGQFYDLK ELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQV YGFYDECLRKYGSI---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-SIGV PIKILHEAEGHVVTLETSTGEVYRGKLVEAEDNMNCQMSNINVTYRDGRVAQLENVFIRG SKIRFLILPDMLKNAPMFKKVNAGRGKSAILRAAARGGGRGGRGRGG--MQNEAGENVDM YIPRKCSASNRIIAAKDHASVQLNIALVDEKTGRMTGAYKTYAICGEIRNMGESDDCINR LSKKDSILAKMARGPRKHLKRLAAPKHWMLDKLSGVFAPRPSSGPHKLRESLPIILFIRN RLKYALTYDEAKKIVMQRLIKVDNKVRTDLTFPAGFMDVISIEKTSENFRLVYDVKGRFA VHRITAEEATYKLCKVTKQCTGPKGVPYISTHDGRTIRYPDPLIKVNDTVQV-------- ---------------------------------------------------------DTA GQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADNNIVIMLVGNKSDL RHLRAVPTDEAKALLREWTV-LHRTSALDSTNVETAFHNILTEIFRRFQARQMRSDADGP ----------------------MSARYDRAITVFSPDGHLFQVEYAQEAVKKGSTAIGIR GKDIVVLGVEKXAVAKLQEDRTVRKIALLDEHVSMAFAGLTADARILINRARVECQSHRL TVEDPVSLEYITRHIAQLKQKYTQSNGRRPFGLSTLIVGLXWFSHLYQTDPAGTYHEWKA NAIGRSAKTVREYLEKHYTEEAVTDKSTVKLALRALMEVVQSGAKNVEFAVMKRGEXLKM LEPEELEKYIAEIEKEREED---------------------------------------- -------------------------------LLLEEEFIKNXERLKPQEEKQXEERSKVD DLRGTPMSVGSLEEIIDDNHAIVSTSVGSEHYVSIMSFVDKDQLEPGCSVLLNHKVHAVI GVLGDDTDPMVTVMKLEKAPQETYADIGGLDQQIQEIKESVELPLTHPEYYEEMGIKPPK GVILYGEPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPS IVFIDEIDAVGTKRYDSNSG---------------------------------------- ------------------------------------------------------------ -------------------------------------------PYSPFQSSNKAEYALAR VDDLVNWARKSSLWPMTFGLACCAIEMMHFAAPRYDMDRFGVTFRASXRQADCIIVAGTL TNKMAPAFRKIYDQMPEPRWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGSPP- ---------------------------ADFYIRYYVGHKGKFGHEFLEFEFRPDGKLRYA NNSNYKNDTMIKKEAYVHKAVLEELRRVIDDSEIMQEDDNLWPPADRVGRQELEIVNGDE HISFTTAKIGSLVDVNQSKDPEGL---------------------------XXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------ ------------------EDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGF LCVFAVNNGKSFSDINLYREQIKRVKDAEEVPMVLVGNKVDLPARTVDAKEAQNFASSVS IPYVETSAKTRQGVDDAFYDLVREIRKYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-KIELCS FSGYKIYPGHGSRFIKVDGKSFMFLNKKSKRLHLTKRNPRRISWTVLYRRKHKKGQVEEV TKKKTRKTQKFQKAVAGATINEIMAKRNQKPEVRKAQREQAIRAYKEKQKAKVKAPGRVG G--MKINVAYPATGSQKCFEIDDDLKLRHFYEKRMAQETEADSLGDEWKGYVVRITGGND KQGFPMKQGVLTNGRARLLLKKGSGCYRPRRKGERKRKSVRGCIVDSNLSVLNLVVIKKG EQEIPGLTDKTQPRRLGPKRASKIRKLFNLSKEDDVRQYVIKRALPQRYKAPKIQRLITP MVLQRKRHRLALKKRRREKNREEESAYAKILAQRVKEAKERKNERRRSSSMRR------- -----------------ELSALRVAKVTGGAANKLSKIKVVRKSIARVLTVIHQTQRENL RKFYKPKDLRYKKTRAMRRRLTAHEQGLKTAKTMKKERAFPVRRYAVKAAGDGPKVTKQV FFDISIGGEPMGRIEIGLFGGSVPKTVDNFVALATGA-GYKGSKFHRVIKDFMIQGGDFT RGDGTGGKSIYFADENFKLSHYGAGWLSMANAGKDTNGSQFFITTVKTSWLDGRHVVFGK VVKGMKVVRRIENTKTGQDRPNKDVVITDCGEIVVDSPYSVKKEAS---KKKLSLKFVID CTHPVEDGIIDVADFEKFLNQRIKVEGKLNNMKNKXTVNAEIEFSKRYLKYLTKKYLKKH NLRDWLRVVANAKDSYELRYFQINNEEEE-------GKGDMEVTQYGGCEGPDAMYVKLV SCDGHEFVIKRDHALTSGTIKAMLSGPGQFAENETNEINFREIPSHVLQKACMYFTYKVR FTNSSTEIPEFPIAPEIALELLMAANFLDC-KVFKLEEIKEHNNGKSSWLIIHDKVYDVT KFLDEHPGGEEVLLEQSGKDATESFEDVGHSTDARELMKDYYIGDLHEDDRVPTGSWL-- -----------------LLQHLHNGWQVDQAILSEEDRVVIIRFGHDWDPTCMVMDETLY KCAEKMXNFAVVYLVDITEVPDFNKMYELYDPCTCMFFYXNKHIMIDLGTGNNNKINWXM EDVQEYIDIVETVYRG-------------------------------------------- ------------------------------------------------------------ ------------------------------KPDVAYSDIGGMDIQKQEVREAVELPLTHF DLYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTASFIRVVGSEFVQKYLGEGPRMVR DXFRLAKENAPSIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTVNVK-- ------------------------------------------------------------ -----------------------------------------------------PLDRQSI GDRILLNLKLFDKVDPEKVTLESRFKEDLELDSLDHVEVIMAIEDEFGFEIPDQDAEHMH TPALIVQYIMDKFDV----------LKTIEFETSEDVDVTPTFDSLNLKDDLLRGIYAYG FEKPSAIQQRAIKQIVKGRDVIAQAQSGTGKTATFSISSLQALDTQLRETQVLVLSPTRE LAGQIQKVILALGDYMSVQCHTCIGGTNIGEDIRKLDYGQHIVSGTPGRVFDMIRRRNLR TRSIKMFILDEADEMLNKGFKEQIYDVYRYLAPATQV----------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------XXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXX-----------YFINIDASSEECFFEEVVKDTSLTLTFEVAEGGFLDI DVNVMGPHGESLWSKERESNGKFTIKANADGAYKYCFGNKMSSMTPKMVMFTMETGEKHV ESHNKLAQAVRSLSEALLGVKHEQEFMEVRERVHRSINDNTNSRVVLWAFFEALVLVAMV LGQIYYLKRFFEVRRVIMAATLKPYLEAVRKTLHASMCLENFPSQVVEXHNKPEVEVMSS KELLFTPVVISRNERERVKIEGSINSIRISIAIKQADEIEKILCHKFTNFMMQRAENFFI LRRKPIEGYDISFLVTNFHLEQMLKHKLVDFVIHFMEEIDKEVSNLKLAVNTRARISAAE FLQCFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXX----------------CYQNFVDYHRCHVKEDHA PCEYFKWAYKNLCPPQWYTKWDEQIEAGTFAGNL-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------KFVALGI DPPKGVLLYGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMART KKACIVFFDEIDAVGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDT LDPALVRPGRLDRKVEFGLPDLEGRKHIFTIHARSMSVEKDIRYELLARLCPNXTGAEIR SVCTEAGMYAIRARKK----------------------------------ELTHINIVVI GHVDSGKSTTTGHLIYKCGGIDKRAIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITI DIALWKFMTTKFQVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQT REHALLAFTLGVKQLIVGVNKMDSTEPPYSGDRFNEIQREVSSYIKKIGYNPDGVAFVPI SGWHGDNMLKMSWYKGWKKKSGKTLFEALDSINPPKRPTEQPLRLPLQDVYKIGGIGTVP VGRVETGVIKPGMVVNFAPVNITTEVKSVEMHHESMPEALPGDNVGFNVKNVSVKEIKRG NVAGDSKNDPPLGAENFSAQVIVLNHPGQISAGYAPVLDCHTAHIACKFSELIEKIDRRS GKKLEDSPKFVKSGDAAIVLMIPSKPMCVEKFSEYAPLGRFAVRDMRQTVAVGVIKSVTK KAATSGKVTKAAQKA--------------------------------------------- ------------------------------------------------------------ ---YVACGGLDNICSXYNLKTRDGNVRVSRELPGHTGYLSCCRFIDDGHIVTSSGDMTCA LWGIESGQQVTEFVGHSGDVMSLSLSPDMNCFVSGACDASAKLWDVRDGNCKQTFVGHES DINAITYFPNGHFFATGSDDATCRLFDIRADQEVGMYSHDNIICGITSVAFSKSGRLLLA GYDDFNCNIWDTLNQDRAGVLAGHDNRVSCLGVTQDGMAVATGSWDSFLKIWNMSYSYLF KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMINIEGKQIKLQIWDTAGQES FRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLEGRR DVSKEEGEAFAREXGLIFMETSAKTASN-------------------------------- ---------------------KRYTMELGDVTPHNIQQLKKLNQVVFPVSYNSKFYKDVL ELGELAKLAYFQDIVVGGVCCRVDTTEGVRSLYIMTLGVLAPYRRYGLGSMMLRHILDRC EKDGNLESVYLHVQISNEDAIKFYEXFGFSVVEKKENYYKRIEP------------MPRQ IMEIKDFLLTARRKDAKSVKIKKNVKFKVRCSKYLYTLVIQDREKAEKLKQSL------- ----SKLQRDQLREHVENVLQKPRKFTETIELQITLKNYDPQRDKRFSGTVKLKHIPKPK LKLCVIGDERHLDEAKSIGLDCKSMDDLKKLNKDKKLVKKLAKSYDAFLASDTVIKTIPR VLGPGLNKAGKFPTVLSHNEKMKDKAEEVKGTIKFQMKKVLCLAVAVGHIKMEREELVAN INMAVNFLVSLLKKNWQNVR---------------MADSDKLSIDSIIARLLEVRGSRPG KNVQLTEAEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYS IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDNGLLCDLL WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKLGFGTLSGGRPLTPPRNAQQQK GK-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXX---SNIQNLTDPFADASKIHIRIQQRNGRKTLTTVQGINPKYDLKRL XENMQKEFACNGTVVEHAEXGEVIQLQGDQRMSIKDFLLRMNLESQLKVHGF-------- -----LLLICTCAYIRSIFPSIIDKHKEGLLGIFWKCARIGERKSPWVGFCCIAMAFSIL FLT--RVVSSVARQLPGASKHSKPFGLASVAARKFTASAEVSTILEERILGSSQANLEET GRVLSIGDGIARVYGLNNIQAEEMVEFSSGLKGMALNLERDNVGVVVFGNDKLIKQGDIV KRTGAIVDVPVGEELLGRVVDALGNPIDGKGPLNASARARVGVKAPGIIPRTSVKDPMLT GIKAVDSLVPIGRGQRELIIGDRQTGKTAVAVDAIINQKRFNDSDDEKKKLYCIYVAIGQ KRSTVAQLVKRLTDADAMKFTIVVSATASDAAPLQYLXPYSGCAMGEYFRDNAKHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSEAFGGGSLTALPIIE TQAGDVSAYIPTNVISITDGQIFLENELFYKGIIPAINVGLSVSRVGSAAQTKAMKQVVA SMKLELAQYREVAAFAQFGSDLDASTQALLNKGVRLTELLKQGQYVPMDVSEQVAVIYAG ARGYLDKLDPSSITKFEQAFLKHIKASHQSLLDTIKNDGQITESTENQLKEVVVNFLAGF ---LYTAPFKVLEKPNLKIKKPGFLKMPSAMTVFGVAMVSYFLVTGGVIYDVIVEPPSIG STTDERGHSRPVAFMPYRINAQYIMEGLASSFLFALGGMGFIILDQTNNPLTPKLNRILL LMTGIGSILLSFFMLRVFMRMKLPMPKVKRSRKPPPDGWELIEPTIDELDGKMKEAETDP HEGKRKVEALWPIFRIHHQKSRYIFDLFYRRKAISRELYDYCLKEKIADGNLIAKWKKQG YENLCCLRCIQTRDTNFGTNCICRVPKGKLEEGKIVECIHCGCRGCSGEYAQVTKMLGNG HLEAMCFDGVKRLCHIRGKLRKKVWINQSDIILIGLRDYQDSRADVIMKYSSDEARNLKA YGELPETAKINEDGEDMITFDEADDKLVRFLMKLSHETVTIELKNGTQVHGTITGVDVSM NTHLKAVKLTQKGREPVALDTLSIRGNNIRYYILPDSLPLDTLLVDDAPKGRG------K PKSEMTPEEMAAREQEEFNTGPLSVLTQSVKNNTQVLINCRNNKKLLGRVKAFDRHCNMV MENVKEMWTELPKTGKGKEKG-PVNKDRYISKMFLRG-----------PVLIDARGHLLG RLAATIAKTLLQGQRVVVVRCEEINISGSFYRNKLKYLDFLRKRCNTNPNRGPYHLRAPS KILWRVIRGMLPHKTNRGKEALYLFKSFEGIPAPYDKMKRMVIPSALKITRMKPTRKFCR LGRLSHEVGWKYQSVIATLEEKRKVRSHKFHVQRKKAQKLEQTAK--------------- GDPAKGKKLFTKKCTQCHTIEKGGKHKTGPNLYGLIGRKTGQAPGFSYTAANVNKGITWS RETLWVYLENPKKYIPGTKMVFAGLKKEXERADLIAYLEEACKIFIERTLAIIKPDAIYE EIKDIILRTGFSILSTRRVQLTPEQASDFYAEHYGKLFFPSLVAYISSGPIIALALAREK AIAHWRDLIGPTNTLKARQTHPDCLRAIYGTDDQSNALHGSDSFSSAEREIRFFFPDSI- -------------------------------------------------------MFEAR MSDTTVMKRLMDAITTLIDDGSFDISSKGISLQAMDSSHVALVAMCLRNEAFDPFRCDRN LSLGIQCNKXGKILKCSANNDVMTLKAEDDGDVLNMVFESPNGDRMSEFAMKLTDIDIEQ VGIPETEYSAIVKMPSSEFSRVCRDLSNFGESVTICVTKDGLKFSVKGDSSNASMKFSQN GAGDDGND-VSIDLNDPCTLTFAVKXLNHFTKAAPLSERVTLSLSNDTPLVVEYKIGDLG HIRYYLAPKMEED---RTLPTAQIKASAKQGQVVAVIGAVVDVQFDEGLPLILNALEVEG RESKLILEVAQHLGENTVRTIAMDGTEGLVRGQPVTDTGYPIRIPVGQETLGRIINVIGE PIDERGPIKTDKFLPIHQEAPAFVDMSVEAEILVTGIKVVDLLAPYAKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGFSVFAGVGERTREGNDLYEEMKESKVIDLEGTGSKVALVYG QMNEPPGARARVALTGLTVAEYFRDAEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTKTGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIA ELGIYPAVDPLDSTSRILDPSVVGHEHYDTARSVQKILQDYKSLQDIIAILGMDELSEDD KLTVARARKISKFLSQPFQVAEVFTGHEGKFVSLEETIRGFKAVLSGELDHLPEVAFYMT GNLDDVVKAAERMAAEQ------------------------------------------- -----------------------YLTNEGIQYLRDFLHLPPEIVPSTLKRQQGGEDRRDY RRGADSDKKADSGAGTT-GKGTSKLRPEVISDLKDQTSFNEEEITEWYKGFLKDCPSGHL TVEEFKKIYGNFFPYGDASKFAEHVFRTFDANRDGTIDFREFICALSVTSRGQLEQKLKW AFSMYDLDGNGFISRSEMLEIVRAIYKMVGSVMKMPEDESTPEKRVDKIFRQMDKNADGK LSFNEFLDGAKSDPSIVRLLQCDP------------------------------------ ------------------------------------------------------------ ----------------------------SDVPGETMVKLYCPKCCDVYTPKSSRHHHTDG AYFGTGFPHMLFMVHQEYRPKRPGTQFTPRLYGFKIHPVAYQLQIQAASNFK-------- -----GYRRGTRYMFSRDFKRHGVTGLSRYLKVYKVGDYVDIKGDGAIQKGMPHKSYHGR TGRVFNVTKHAVGVVVNKRVRGRILPKQINIRIEHIKHSNCRLDFIKRMQQNEELKAKAR AKVELKRQPVGPRPAHFVSSKKTK--------------TKSTYKLVSPDKPDMSWDGVTD RASDYMFMKELLQGMAITFGHIFKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAICPAQAITIEAETRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEY ATETHEELLYNKEKLLNNGDMWEGE------------MASQPKVARTD-------DV-EQ DAIEKIDEVQNEIDRLNEQASEEILKVEQKYNKLRQPHFSKRNELISRIPDFWLNVFVNH PQLSTLLTEQDEEVLHYLSQVEIEEFEDIKSGFSVTLHFSKNPYFENQFLKKEFHLNSSK ASGIQWKEGKDLTKQSKKRS-LDSESFFTWFSDTTDAGADELGEVMKDDIWPNPLQYYLS SELEPVSGDDEEFDDEEKQLTKEEELLLQDFSRNVSTKSSALFYVNALIISAVPLWIYWR IHRMDPIILFVLMTGISTYLLSFAYKNVKFVLKHKAAQKVEDGVTQEIMKKFADDKKVSK KEKDERILWKKNEVADYQSTNYSIFYNNAMFFALVILCSFCFFKSFSPNVNYILSMGAAS GLVALVSTGSKASQGKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQT VCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIIVYDITNQDTFNRAKSWVKELQRQ ANPNIVIALSGNKADLRMVEYEEAQAYAEXNGLLFMETSAKTAMNVNDIFLA-------- ------------------------------------------------------------ ------------------------------------YGEIEEMNVCDNLGDHLVGNVYVK FRKEEDAEKAMNALNLRWFNGRPLTCDLSPVTDFREACCRQYELGECTRGGFCNFMHLKP ISRDLRKRLYGRSKKSRSRSRDRS---------HRRRSRSRDRDR--------------- ------------------------------------------LIEADSIEKIFEVDSHLG CAMSGLIADSRTLIDRARVEAQNHWFTYDEKMSVESVTQSVSNLALAFGDDDAEPGAMSR PFGVALLFAGIDENGPQLFHLDPSGTFIRYDAKAIGSASEG------------------- ----------------------------------------------XXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXELTEDLLDYEEEQQAPAKKVKGSYVSIHSS GFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILSMDVLCQAKSGMGKTAVFVLATLQ QLEPVDGEVSVVVLCHTRELAFQISKEYERFSKYMPTVKAAVFFGGMPIQKDEQTLKKNT PHIVVGTPGRMLALCKALNLKNVKHFILDECDKMLEALDMRKDVQEIFRMTPHEKQVMMF SATLSKEIRPVCKKFMMDPMEVYVDDESKLTLHGLQQHYVKLRDNEKNRKLFDLLDALEF NQVIIFVKSVQRCMALTQLLLEQNFPAIAIHRAMTQEERLSRYQQFKDFSKRMLVATNLF GRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAVTFVSDETDAKVPPCFSDLG KSARDILNKGYHLNTWKVEAKASTDSGVKFKSTGVHNTENGKVLGVLESEYSFKDYGLKF VDKWSTDNVFTLECSLENKGIEGLKLTAEGSFNPSSGNKRGQLKTNYKMXFLNLNLDVD- SAGGATVRGAGVASYNGFLAGYQSAFDKSQLISNNLAFGLDGGDFSITANVNDGQEFLGA VHHKVSRDLETGVTMGWAAGASATTFNFGVKYNISDDTNIKIKVTNQSLMGVSLQQRLKD GLSLTLSGSVDVKNLNTGRHAVGLSVEYE-DSAREKALNDYRKRLVEHKENEARLKEMRE QLKAETKNYDKSEDDLKALQSVGQIVGEVLRQXTEDKFIXKANKRPRYVGGCRRTLDKSQ LKXGTRVALDMTTLTIM------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------------ES LVSVISKFYESYVNSTPRKLKIVDAYLFYILITGIIQFVYCCLVGTFPFNSFLSGFVSCV GSFVLGVCLRVQSNSENKADFINISPERAFGDFIFAHVVLHLVVMNFIGXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXVIDHYENPRNVGSLNKKEVNVGTGLVGAPACGDVMRLQIKVDDDG KIIDAKFKTFGCGSAIASSSLATEWIKGKSMDDAGKIKNTEIAKELSLPPVKLHCSMLAE DAIKAAIKDVAKK--MLVLVLGDLHVPHRTNSIPPKFKKLLVPGKIQHILCTGNLCAKET YDYLRSIANDVHIVRGDFDENTNWPEQKVVTVGQFRIGLCHGHQIVPWGDTESLAMLQRQ LDVDILISGHTHKXDAFEHEQKFYINPGSATGAY-------------------------- ----------------MGRFMKSGKVVLVLNGRFAGRKAVIVKNYDEGSTEKPYGHALVA GIDRYPRIVTKGMSKKKLKQRSKIKTFVRVYNYNHLMPTRYSVVTLDKAAVNKDAFKDPS KR-----------------------------ERTFIMVKPDGVQRGLIGEIISRFEKKGL KLVAMKFMQPTEEHLRVHYADLSSKSFFPGLVKYMASGPVCAMAWEGQAAKYGRLILGAT HPQDSAMGTVRGDFCVDIGRNVCHGSDSPESGAKEVALWFKPEELVQWTSCSEAWVYESQ AKKPTKKAKNPTDKALKAKKAVAKGTFINRKKKARYSVHFRRPKTLSLPRAPKYPRQSAP GRPKLDQFKIVKYPLTTESAMKKIEDNNTLVFIVDKRSNKNMIKAAVHKLYSIEVQRVNT LIRPDGEKKAYVRLASDYDALDVANKIGIIMAAKQRMKVASDKHQKNITSRGNVPKSLMN KEDGPAVGPWLLALFVFVVCGSAVFQIIQSIR-XXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXGDTIFGKIIRGEIPSKKIYEDDQAFVFHDINATAPVHFLVIPK KPIPQLSSDEQLLGHLLLVANKCAKQAEGYRVVINNGXNGCQSVYHLHLHIIGGKXLGWP P-------FSALVGQKERRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVTYKN LKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSRDRDRIGISKQELVACWRRR------ ------------------------------------------------------------ -ALYFHIQETEKKCFIEEIPDQTMVTGNYKVEMFDEQKNTFVPTLVGLGMLVQVKDPEEK ELLSRMYAAEGRFTFTSHTSGEHQICLHSNSTAWFGGGKLRVHLDIQVGDHAIDYQDVAN KEKLSELQIRVRQLLEQVEXLQKEPNYQRYRE---------------------------- ------------------MFYHVSLDHEVLLHPCYFGPSLLNVVKQKLFNEVEGTCSGKY GFVIAVTTIDSIGSGQILPGRGFVNYPIKYKAIVFRPIKGEVIEAIVTQVNKVGMFVEAG PLSCFISKHSIPGDMEFDPESTPPCYKTKDEDVVIQVDDEIRVKIIGTR----------- ----------RLYVKAVFTGYKRGLRNQHENTSLLKIEGVNDKKDTRFYMGKRCAYVYKA KNLTACPGHEKRSKLRVIWGKVTRHHGNNGAVRAKFSSNL-------------------- ------------------------------------------------------QIWDTA GQERFHTITTSYYRGAMGIILVYDITNQRSFDNITKWLRNIDEHANEDVEKMILGNKCDM EDKRQVSNERGIMVAKEHGIPFLETSAKANINVEQAFLDLAQAILDK------------- --------------------------------------------------------ERNT KAKSDDNVPEGAIPAYLLDRETQTRAKVLSNMIKQKRKEKAGKWEVPLPKVKGVSEAEVF KVIKSGKSRRKCWKRMVTKVCXVGDGFTRKPPKYERFIRPMALRFKKAHVTHPELKATFC LPIIGVKKTRSSPMYTGLGVITKGTVIEVNISELGLVTQGGKVVWGKYAQVTNNPENDGC INAVLLVMAARPMVSVFTEKTEETGTTVQLPAVFRAPVRPDIVRFIHTNVRKNTRQPYAV SKKAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRK VNTAQKRYAITSCIAATGVPALVMAKGHRIEGIPEVPLVVSDKVEEFKKTKEAVTLLRKS GAWADIDKVYKSKALRAGRGKMRNRRRTQRLGPLIIYNKNNGVVKAFRNIPGVDTIPVSR LNILKLAPGGHVGRFCIWTESAFKQLDALYGTWTTPSQMKKNFNLPQQIMSNSDLGRLLK SDEIQNAIRQPKRQRGRRILKKNPLKNTAIMLRLNPYADVTRRTAIGAYKRQAKIAERRG LPAPEKRKQAVSKKAKP-AGEQELDSKMLQIQSKRFYLDVKQNRRGRFIKVAEVGAGGRK SRLLLSMSNAAEFRDHLIDFTDFYETLDPPNPDNVPEDGKLKSSHIIGGTRRYYLDLKEN QRGRFLRVSPRGGPRSQIAIPAQGMGEFGDTLSKLLEDYGTDDQETSVELPESKSMRVEN KMFYFDIGQNNRGTYMRISESNFRTAITIPERAWTRLRDIIGEYLDKDPRRNSEALMRSS INQKLVESGESERLKDILRTRLIECGWRDELKAHCKEIVKRKGLEHVTVEDLVAEXTPKG RALVPDDVKKSYL------------MNIRNATPEDLMNMQHCNLLCLPENYQLKYYFYHG LSWPQLSYVAEDENGKVVGYVLAKMEEDPEDE-PHGHITSVAVKRSHRRLGLAQKLMDQA SRAMVESFGAKYVSLHVRVSNRAALHLYKNTLGFEISKXEPKYYADGENAYEMKRNLGVF ----MAHTILLVQPSNSPESRTYSDYESLTEMLRNFGRIYEEHLKRNHPRQPSITYDIXQ LFDFIDQFTDL----------------------------------XXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSHRKFSAPRHGHLGFMPKKRSKRHRGKC KSFPKDDPKKPVHLTAFLGYKAGMTHIVREVNRPGSKVNKKEIVEAVTVIETPPMVVVGV TGYIETPRGLRTIGTIWAEHLSEECRRRFYKNWYHSKKKAFTKYAKKWQDDDGRKVIERD FNKLIKYCKVIRVLCHTQMKLMNQRQKKAHLMEIQVNGGTIADKVNWAKEHLEKQVPVSS VFMQDEMLDVIGVTKGKGFKGVVSRWHVKKLPRKTHKGLRKVACIGAWHPARVGFGVPRA GQKGYHHRTEVNKKVYRVGAGIHTKDGKVVKNNASTEYDITEKSITPMGGFPHYGEVRND FLMLKGCVMGPKKRVLTLRKSLMVHTKRVATEEIKLKFIDTSSKFGHGRFQTKEEKKAFM G-----MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGRPINLG LWDTAGQEDYDRLRPLSYPQTDVFLICFSLISPAXFENVRAKWXPEVSHHCPNTPIILVG TKLDLRDDGETIEKLREKXLAPITYPQGLAMAKEVRAVKYLECSAL-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AELGTSGNVDANNSLILKGRYQQK HIETVLRRYIKEYVTCHTCRSPETLLEREIRLFFLQCQHCGSRSSVASIKSGFQAVTGKR AAMRAK--YDEAIEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVSRPADK DYSIHRLILGTHTSDEQNHLLIASVQLPNDNVQFDAAQYDHDKGEFGGFGSVSGKIEIEI KINHEGEVNRARYMPQNPTIIATKTPSSDVLVFDYTKHPXKPEPNGECQPELRLTGHQKE GYGLSWNPKSXGNLLSASDDHTICLWNVNAAPAEARTLEA-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PRPSTARVYADVNMHRPREYWDYESYVVEWRSQDDFQLVRKLGRGKYSEVFESYNI TNGDKCVAKILKPVKKKKXKREIKILENLRGGTNIIRLYAIVKDPVSRTPALVFEHVNNT DFKQLYQTLTDFDIRFYIYELLKALDYYHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA EFYHTGQEYNVRVASRY------------------------------------------- ------------------------------------------------------------ ---------------------------------------------EAKKLKRQDIFKRAE KYAKEYATAERELINNKRAARKANNYYVPAQPKVAFVIRIRGINGVPPKPRKVLQLFRLR QINNGTFVKLNKATINMLRIAEPYITWGYPNLKSVRELLYKRGFGRVDNRRIALTDNSII ENKLGKCGIICME----------------------------------------------- ---------------------------------------------------ARKPKMCSF LEWRDHKIVYKRYASLYFCAAIEPDDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEK AYYMLDELLIAGEIQETSKKNVLKAIAAQDMLQEEEPKSILEELGI-MSKTHPPELKKYM DKRLHLKLNGGRSVIGVLRGFDPFMNLVVDESVEETKTGDRHSIGMVVVRGNSIVLMEAL DRIEFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTI RLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRSERGSDVIIM LVGNKTDLSDKRQISTEEGEKKAKELGVMFIETSAKA----------------------- -----------------MPVRYDLAVGLEKGFKVTTPKPRKSRTRGKLYKRTKFTRDLVR DIVGFAPYERRLMELLKISRDKRALKFAKARLGSHIRGKXKREEISGLLQKQRQ-XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------------- ------------------------------------------------------------ ----------------------------KFLTKGDNNRVDDRGLYAPGQLWLKREDVVXR ARGFLPYVGIVTILMNDYPQLKYAVLGCLGIYVLIHRE---MNPEYDYLFKLLLIGDSGV GKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQ------------ ------------------------------------------------------------ -----------------------------------------------------------E ESLGEEVMRMSTEEIVSRTRLLDNEIKIMKSEIMRISNELQTQKEKIKENTEKIKVNKTL PYLVSNVVELLDVDAQDDA-EEGANVDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDPEKL TPGDLVGVNKDSYLILEELPHEFDSRVKAMEVDERPTEQYSDIGGLDKQIQELIEAVVLP MTHRDKFETLGIQPPKGVLLYGPPGTGKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGA KLVRDAFSLAKEKKPAIIFIDELDAIGTXRFDSEKAGDREVQRTMLELLNQLDGFHPSTD IKVIAATXRVDILDPALL------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------WDERQVVLVGNKC DLEEERVVSTDRGXELADRLGLEFFETSAKDNINVKAVFERLVDIICDKMTETLDSD--- -----------------GKVHHAAVSRDYISQPRLTYKTVSGVNGPLVILDDVKFPKFAE IVTLTLADGSKRSGQVLEVSGNKAVVQVFEGTSGIDAKFTQCEFTGDILRTPVSEDMLGR VFNGSGKPIDKGPNVLAEDFLDIQGQPINPWSRIYPXEMIQTGISAIDVMNSIARGQKIP IFSANGLPHNDIAAQICRQAGLVQLPSKSVMDSHEDNFAIVFAAMGVNMETARFFKQDFE ENGSMENVCLFLNLANDPTIE--------------------------------------- ---------------------------------------------PMPNDDITHPIPDLT GYITEGQIYVDRQLHNRQIYPXINVLPSLSRLMKSAIGTGMTREDHSDVSNQLYACYAIG KDVQAMKAVVGEEALTSDDLQYLEFLGKFEKNFITQGPYENRTIFDSLDIGWQLLRXFPK EMLKRIPKETLNKYYPR--EGPGFVGXKFCQECNNMLYPKEDKVNKVLLYACRNCDYQQE ADNPCIYVNKITHEVDELTCIVGDVIADPTLPRTQDHPCPKCGHREAVYFQSQTRRAEEG MRLYYVCTNP--------KMPYKVADINQAADGRKAIEIAENEMPGLMTMRKVYGPSKPL KGARIAGCLHMTVQTAVLIETLVELGAEVQWSSCNIFSTNDAAAAAIAATGVPVFAWKGE TDEEYVWCIEQTLVFADGKPLNMILDDGGDLTNLVHEKYPQYIDGIKGLSEETTTGVHNL YKMLKNGTLKIPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGKVAVVAGYGDV GKGCAQALKAYGARVLISEIDPICALQAAMEGYEVTTMEEAVKTARIYVTTTGCTSIVRG EHFEEMLDDSIVCNI----------------------------YTMKSGRHIIVLAEGRL VNLGCAHGHPSFVMSNSFTNQVLAQIDLWTNPKQ-SVCVKVLSKKLDEEVARLHLDHIGA KLTQLSETQCSYLGLPKEGPYKPEMYRYAEEAEQPTVATVEEPFDLVRLSLDEKXYVKMR NDRELRGRLHAYDQHLNMIXGDAEETVTTVEIDDETYEEIYKSTKRTIPMLFVRGDGVIL ISPPMRAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------- ---------------------SCEFGSATYYAYCGFGGMLSCGLTHTAIVPLDLVKCRLQ VDGAKYKNLFTGFKITIAEEGVRGLGKGWAPTLIGYSMQGICKFGFYEGFKIFYGNLIGE EKSYLYRTSLYLAASASAEFFADIALCPMEAVKVRIQTKPGWATTLREGLPTIVKEEGIG GLYKGLVPLWARQIPYTMMKFACFERTVEALYKHVVPKPRAECSKGEQLGVTFTAGYIAG VFCAIVSHP-----------------------------------VSVIGTLTALQWFIYD TVKVVCRLPRPPPPEMPASLKAKLQHWVAERVMSAGLYAVIPAAFILAMDTALTSLVIHS HWGISGVFADYMHLSITAFACLMNFNYNDVGLVKAICMLW---NDQVEEDAGELKFPKEF ENAETXLVSEVHRKKQNEEADEEQELSKVFTKTLSYAQRFSKYXNKETISAVRELLXEKR VHKFELAALANLAPETAEEAKTLIPSMEDRFPDEELQPILDDIKTKRSFQY--------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------DLVKESQ AREQFDQIQKFVQGTVAEGAPVIPISAQLKYNIEVICEYIXEKIPIPLRDFTSEPRLIVI RSFDVNKPGSEVDDLKGGVAGGSILRGVLKIGQEIEVRPGIVSRDSNGTLTCTPLRSRIV SLFAEHNDLQYAVPGGLIGVGTKIDPTLCRADRLVGQVLGAVGALPFIYTELEISYFLLR RLLGVRTEGDKKGAKVQKLSKNEVLMVNIGSLSSGGRVLAVKGDLAKIGLTNPVCTEIGE ------------------------------------------------------------ -------------------------------------------------------KNPMS DPSMMTEMMKGNLTNMLPMIVIGGWINWAFSGFLTTKVPFPLTLRFKEMLQRGVALPSLD AAWVSSVSWYFLNVFGLRSVYTLILGQDNAADQTRAMQDQFTGNAAAMSQDPNKXFKAEW EALEMCSYKWALEGADKELF-FLWDWLSGMLNFLGLYKKSGKLLFLGLDNAGKTTLLHML KDERMQQHMPTLHGTSEELTMGGMRFTTFDLGGHKQARRVWKNYFPAVDGIVFIIDTADR ERIPESISELHSLMADEQIGECPIMILGNKIDKQGAASEEEIRHYFGXHGRTTGKGNIPK SELRPIELFMCSILKRQGYGEGFRWLAQYL--IRRNRPGTKSSEWCNWPPQSFEEMDSTV LVQQYIQQLIKTETFNIDLILEPPEGQDEGVWKYEHLRQFCMELNGLAVRLQEECNPETC TQMTATEQWIFLCAAHKTPKECPAIDYTRHTLDGAACLLNSSKYFPSRNSIKESSV---- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------KVDQGTLFELILAANYLDIKGLLDVTCKTVANMI KGKTPEEIRKTFNIKNDFTPAEEEQVRKENEWCEEKXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------RPPMAVTNAVSWRSEGIKHRKNEVFLDVIESVNLLVSSNGNV LRSEIVGAIKMRVXLSGMPELRLGLNDKVLFEHTGRGKSKSVELEDTKFHQCVRLSRFEN DRTISFIPPDGEFELMSYRLST-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------MGILEK IAEIEREMARTQKNKATEYHLGLLKAKLARYRAQLIEPTSKSGPKGEGFDVLKSGDARVA LIGFPSVGKSTLLTTVTKTQSEAAGYEFTTLTCIPGVIEYNGANIQLLDLPGIIEGAAQG KGRGRQVIAVARTSDLVVMMLDATKRXNTKELLETELEAVGIRLNKQRPNIYFKQKKXGG IKFTATLNLTKCDEKMVQNILHDFKIFNADVIFREDCTCDEFIDVIIGNRVYMSCLYVYN KIDQISMEEVDKLARXPHSMSLAVT-KLNMDYLWKSCGNTVGLMRVYNKRQGKKPDFRRS NLLRGG-CTIEHVCHAIHRTIVAQFRYALVWGXSCKFSPQRVGISHTVCNDDVVQIVKKM AKHHPDLIFCRKQPGVAIGRVCEKCDGKCVICDSYVRPCTLVRICDECNYGSYQGRCVTC GGPGVSDAYYCKECTLTEKDRDGCPKIVNLGSAKTDL------------XXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXRIKVANPVAELDGDEMTRIIWEAIKEKLVFPYVDVDCKYYDLGLPYRDQTNDQVTIDA AEAILKYNVGIKCATITPDEERVEEFKLKEMWRSPNGTIRNILGGTVFREPIICKQIPRL VPGWTKPIAIGRHAFGDQYRATDIVVPDNGTVELVYTPSGGQTQRIPVFDFKNGGGVTMC MYNTDESIKGFAESCMQYALNKGWPLYLSTKNXILKRYDGRFKDLFQEIFEAKYKKAFDD KGIWYEHRLIDDMVAQALKSDGAFVWACKNYDGDVQSDVVAQGYGSLGLMTSVLMCPDGK TIEAEAAHGTVTRHYREHQKGNPTSTNPIASIFAWTKGLEHRGKLDGNQDLVKWSQALEK ACIDTVDSGKMTKDLAGCIHGLKNVKPEHYLNTMDFLAAVEE----------------MR ILMLGLDAAGKTTVLYNLKLGASVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWR HYYTGTQGLIFVVDCADRDRIEEARQELHRIINDREMRDSVILVFXNKQDLPQAMKPHEI QEKLGLTRLRDXNWYVQPSCAVSXDGLYEGLTWLSSNCKSXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXKVQEIREVTRIERIGAHSHIRGLGLDDALEARNVSQGMVGQVSSRRAAGVILEMI KEGKIAGRACLIAGQPGTGKTAVAMGIAQSLGTDTPFTAMAGSEIFSLEMSKTEALTQAF RKSIGIRIKEETEIIEGEVVEVQIDRPATGTGAKIGKLTXKTTEMETVYDLGQXMIESLT QEKVQSGDIVTIDKA--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------DLTSVMGQYLDRHLVFPLLEFLSET QIYDAADMMQXKLDLLSKTNMVDFAKEVYERLHPDSEVPEFLTTKREDVVHELRCLSQET EPIVKIMDMPEVHIEQSKDGRQLFDTLAKEFNFTTDQLQTLYKYARFQYDCGNYTVAAEY LYFVRVLTPNDDHLAYNALWGKLAAEILMQNWDAALEDLNKLKDVIDSDLQSLQQRTWFI HWSLFVFFNHPKGGDLIIDMFLHDNKYLNTIQTVCPHILRYLTTAVIINKTVLKDLVRVI QQETYTYRDPITEFLECLYVNFDFDRAQQQLRDCETVLSNDFFLVACLDDFIENARLFIF ETFCRIHQCISISMLADKLNMSPEDAERWIVNLIRNARLDAKIDSQLGHVVMGTQAVSVY QQVIEKTKGLSFRSQMLALNIDKKF----MGVDIEPISPGDGVTFPKSGQTVSVHYTGTL TDGTKFDSSRDRGRPFEFKIGAGQVIRGWDEGVAQLSVGQRAKLTCSPDYAYGPRGYPGV IPPNAVLVFDVELLGIKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXISALLGSVIA--TTHLKETFWKERWIESKHKGAEA GNWEWTAGEFYSDEMADKGIKTAENAKFYGLSTKFEK-FSNEGKTLYVQFSVKHEQNIDC GGGYVKLFASDLDQTNMHGESPYNIMFGPDICGPGTKKVHVIFTYKGKNHLIKKXIRCKD DVYTHLYTLVVNPDNTYEVRIDDKKVESGSLEEDWDILPPKKIKDPEAKKPDDWDEREKI DDPEDTKPEDWDKPEHIADPDATKPEDWDDEMDGEWEPPMIDNPEYKGEWKPKQIDNPDY KGKWIHPEIDNPEFTPDEKLYAYEDFGVLGFDLWQVKAGTIFDNVLITDNE--------- --------------------------------------------XXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNAFRLVGDLCHLAAIVLLLLKI WKSRSVAGLSGKSQILFGLVFVTRYLDLVTNFVSPYNTIMKVFFLSSSIATVYLIYTKFK ATYDGNHDTFRMEFLLIPCALLAIVVNHEFSPMEILWTFSIYLEAVAILPQLFMISKTGE AETITSHYLFALGSYRGLYIMNWLYRYYYENNFDVIAVVAGIVQTVLYCDFFYLYITKVL QGKKLQLPA--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------VQPGDVIYIESNSGXVKRQGRCDTYATEFDLEAEEYVPLPKGDVHKK KEIVQDVTLHDLDVANARPQGGQDIMSMMGALMKPKKTEITDKLRKEINKVVNKYIDQGI AELVPGVLFIDEVHMLDIECFTYLHKALETTIAPIVIFATNR------------------ ------------------------------------------------------------ ---------------------------------------------DFEMDEEGDNNLSKL KGSARKRKGRGFITKSSVEKYEVMDLSATGPQRSVEGWILFVTGVHEEAQEDNVYDAFAD YGEIKNLHLNLDRRTGFIKGYALVEFETFKEADEAMKALNGTDILGQTIHVDWAFIRG-- ----AYQLYRNTTLGHTLQESIEELIQCGQISPTLALKTLQSFDEAINKSLHDKVRNRIH FKAKLHTYRFCDNVWTLIMENAEFRTADKLKIVACDGRP--------------------- ------------------------------------------------------------ --------------------------------------------ATDETEECMPLTVVLS HKLNAKLAALRRSGEISWARPDSXTQVTVEYKFEDGACIPLRVHTVVISTQHDEKVTLEQ LKVDLMEKVIKPVIPAKLMDSKTVFHLNPSGKFIIGGPMGDAGLTGRKIIVDTYGGWGAH VGVAFSGKDYSKVDRSAAYAARWVAKSLVKAGLCRRCMVQVAYAIGVAEPLSLTVFHFGT STKSEKELLQIINNNFDLRPGKIVKDLKLKDPIYQKTAAYGHFGR--------------- ---------------------------------------------------------FPT DYPLNPPKMKFTCDLFHPNIYPDGRVCISILHTPGDDPTGYESSSERWSPVQSVEKXLLS VVSMLAEPNDESAANVDAAKCWREDKSRFLECAQRSVRKSLGIMRIEKCFFCSSNVYPGH GVEFVRNDCKIFRFCRGKCHKAFKRKKNPRKTRWTKAYRKTNGKELTVDPAFEFEKRRHV PVKYDRAMWQNTVEAMKRVEEIRVKRQNQYILNRLKVGKKLRKADDVKVYNTQIHLIQSP AATXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------- -----------------------SLEELVALPYGFAQEEWLAWHTIXFFEQLNTLIGVVS HSCTASTCPAMTAPGNVSYSWVDDKG--KKSKCSAPQYIDYITTYINKNVNDHSIFPTKH GXEFPPNFLSIVQKIHRYMFHALAHIYYAHYHQVVLLKLHGHLNTFFAHFMLFNWTFKLI DE-----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------------------- -------------------------LFMRFISNIRDEGMLERGNKFVKKVDSSRLGSQRI KENSKIRVVLELLKEQFKVFVTEGSGRDMAQELKKHKIEVECILDAAIGYVMETIDLVLV GAEGVLASGGI------------------------------------------------- -------------------------------------XXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKAKGDLKEYRVVGRKLPTDALPT PPIYQMRIFAPDRVVAVSRFWYFAKMLKKIKKTNSEILEVSQVYEKKPTVVKNFGVWLRY DSRSGTHNMYREYRDVTVAGAITQCYRDMGARHRARAHSIQIMKVERVISSKCR------ ------------------------------------EMTGHWIKNEQRPISPLTIWKWQL PMNTSLMHRITGCAMTTALYVFGYTICLLPGDYITYLTMVKDWSLGPALITSAKFILAYP LAYHAINGARHLGWDTGKGFDLGTIYKTG----------XXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXX------------------------------------------------------- ------LPXSPCSTLLCSTSWDRTGILWQVETGYMLRLFQGHSSLVQCAAFSPCQRMVAT GSWDHTVRGGEHVHELSAHKSNVHAVAFSR------------------------------ ------------------------------------------------------------ -----------------------------------------HNILATGSWD--------- ---MIIYKDIISGDELFTDAFKGIIEMDTRKDDSLIGGNASTGYEIVLADKKGYLAHLKG YLKSVEAMEVFTGQVLIDYITPFAIFFEEGLEAEK-IAVQCQGGVIIGADSRTSTGAYVA NRFTDKLTHVXDQIYCCTQXVAADTQASDXLSNIHRGIYRMQMEKEPTVHTAANVFENIC YEYXDQLLAGIIVAGWDKDNGGQVFRVPIGGSLIQQPLAMGGSGSTYIYGYADATYKENM TKEEALQFCANCISLAINRDGGSGGVIRLA--------------------XXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXMSIMSYNGAAVIGMAGKDCVAIAADTRFGIQAQTVGTDFQKVFEMGPHLYL GLPGLATDVQTVSQRLXFRLNLYELRXNRRIKPRTFMSMVSNLLYERRFGPYFVEPIIVG LNEKDSKPYIASMDLIGCPMEVEDFVVGGTCGEQMYGMCESLYRPNMEPDDLFETISQAL LNAVDTDAVSGWGAVVHIIEKDKVTTRTLRTRQD-------------------------- ------------------------------------------------------------ --------------EDVELP-GVEKVDIIISEWXGYCLFYESMLNTVIFARDKWLVEGGM MFPDRATLYITAIEDRQYKEEKINWWDNVYGFDMSCIRKVALTEPLVDSVDHKQVCTNSC ILKEIDISTVKVEDLEFCSPFQLMCKRNDYIQALVCFFDVQFSHCHKKTGFSTGPFARYT HWKQTPDCLTVKANEELQGTFACRPNPNNHRDLDFELDVKFNGELSSCTNNTKYKMRMVK EDKATWKSNYFLKLTSLLDEYSKLFIVNVDNVGSKQMQNIRADLRLLLGKNTMMRKAIRG HMDTNPNLEKLLPLIKQNVGFVFTDKELSETRDKILSNKVPAAARAGAIAPVSCTVPAQV TPLGPEKTSFFQALQIPTKISRGNIEILRDVELIKAGEKVGASEATLLNMLSISPFTYGL VIEKIYDDGSILDPEILDITDDQIRETFMKGVARVASLSLAINYPTVASVPHSIVNGFKK LLAIAAVTDIEFEEAKTLKE-LKKGKLLAIIGDEDTVTGFLLGGIGEINKSRTSNFLVVT KDTSIGELEDAFRSYTSRDDIAIVLINQHVADMIRHVLDSYTQAIPAVLEIPSKDHPYDA SKDSILRRARGMFSAEDLRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXLYEEVKLYKNIREREKYDTMADLYAVINTLQCLEK AYIKDAVNXKSYQKSCATLLTQYKSAFKLV------------------------------ ------------------------------------------------------------ -----------------------------------------------XXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---VKKQIGGEKNGGTR IVQVKRMSKSYETQVCPHRLQTRFRDHKRKLRASITPGTVLILVAGPYKGKHVVFLKQLG TGLLLISGPYILNGCPLRRINQRYVIATKTKLDISGVTIPKNINDVYFKKQRTKKTKPAE GEIFENKKEKFEVSPERKADQVTVDKQLVEVIKKREDKKLMFGYLKSDFSLKNHQYPHKM IF-------------------------------------------------------MDA VKIMAKDLVRTRRYVKKFILMKANIQAVSLKITTLKSTNTMANAMKGVTKAMSAMNRQLK LPQIQKIMMEFEKQSEIMEMKEDMMNDAIDDAMGDEEDEEEGDAIVAQVLDELGLQIGDQ LSDL-------------------------------XXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AVVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLG SILGALKGIVNVIGMTKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGSEFVP AREWMRICFELLELLKAHKKAIRRAAVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVC TTVAIAI------------------XVPELNVQNGVLKSLSFMFEYIGEMGKDYIYAVTG LLEDALMDRDLVHRQTAMYTIQHLALGVYGFDCEDALNHLLNYVWPNVFETSPHVVQAFM GAIEGMRLGLGSTRVLQYALQGLFHPARKVRDVYWKVYNTIYIGAEHAMVPAYPRMENDD RNTYM--------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXVLLMGKSGSGKTSMRSIIFANYIARDTRRLGA TIDIEHSHVRFLGNLVLNLWDCGGQEAFMEQYFVNQRDSIFKHVEVLIYVFDVESRELEK DMHYYQSCLEALLANSKDAKIFCLVHKMDLVQEDQREQIFREREDDIKRLSQPLATSIWD ETLYRAWSNIVYLLIPNVSKLETSLXTVAEILEADEVLLFEK------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------CQIHGFVDYVRSKMTYEQFTTLLKAIVTVVGG VVLTATGKISPWTGRFYSLLDPSYAKNNIPIIASVSEHQPTAWSSFYFDLQMLVFMFPAG MYFCFSRLTDANIFIVWYD-EHILCREVMVRLMLVLAPVMCILAGIGVSATLTTYMKNLD PKISSDYNYPMKNEVATAVVFTLTLFLITYVFHCTWVTSEAYSSPSIVLSAKSGDGGRII FDDFREAYFWLRQNTAEDAKIMSWWDYGYQITAMANRTILVDNNTWNNXHISRVGQAMAS PEDKAYDIMRELDVDYVLVIFGGLTGYSSDDINKFLWMVRIGGSTPEGAHIKEADYYTPQ GEFRIDKEGSPTLLNCLMYKLCYYRFGSVYTEQTKPSGYDRVRNAEIGNKDFELDVLEEA YTTEHWIVRIYKVKDLVNRG-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQEVFGIFDNRGDGKV QVSLIGELLRACGQNPTEAEWKKLDDPDKRLTFNEFLPMLKDAAKSKDKMQAGDFVEAFK VFDKEQNGTISKAELRHVLTQLGEKMTEDEVEAMFQGFEDSQXNINYEELIYMVVYG--- ----------------------------NLIECQTLEDLKLSLQSTDYGNFLANEPSPLA VSTIDDKXKEKLVIEFQHLRNHSLPPLSKFLDYITYSYMIDNIVLLVTGTMHQRPLSELL PKCHPLGXFEQMEAIHVASTPSELYNAVLVDTPLAPYFIDCISEQDLDEMNIEIIRNTLY KAYLDDFYNFCKSMGGSTAEVMCNALAFEADRRAFIITINSFDTELTKDDRYKLYPTCGR LYPDGLASLSRADDYDQVRAVAEYYAEYKALFDGAGNNPGEKTLEDKFFEFEVKLMLDAF MRQFQFGVFYAYVKLKEQETRNIVWISECVAQRHRAKIDSYIHIM--------------- --------------------------------------------------EFNMIGSVSW VEDGDILSIGTSSGEVQIWDAAAEKKLRSMDGHECRVGSLAWNTHLLSSGSRNGMIHHHD VRVAQHLV-GTLTAHSQEICGLQWSPNGKHLASGANDNIVNVWPDKFS------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------IFILIGLYYMLSGYGGNFDIGWLLAGISPYFYACVGISMAIALS VVGAAWGILCAGASILGGGVKAPRIKTKNLISIIFCEAVAIYGIIMAIVMGNKKNYFAGY AMFGAGLTVGLGNLACGVCVGIVGSGAALADAQKKGLFVKILIVEIFASAIGLFGLIVAI LQVSKANMGDKMAATKRLGKELNDVVDDTNIFTWTGCLYPDSXPYNKAAFRVQLDFPAEY PFKPPKVTFKTKIYHPNIDEHGQVCLPITLPDHWKPATKVEQVVAALIALINEPEPDHAL RAEIAEEFRRDKKKYMKNAEEYCKKHGEPR---GASESYPMQCSALRKNGHVIIKSKPCK IVEMSTSKTGKHGHAKVNLVGIDIFTGKKYEDICPSTHNMMVPKVNRTEYTLVDVNEMFA TLMTEDGDTREDLKLEVTVLKSMGTEMIMSSKPSKXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXX------------------------------------------ ------------------------------------------------------------ ------------------------LAVSEIMRDPDSGNSKGFAFINFGSFDSSDAAIEAM NGQYLCNRAITISYAFKKEAKGERHGSAAERLLATQNPLAQADRPHQLFADAPAPPTDMP GGPPPPPPSG-------PGMSV--RPPPPPPPT---PPSFNMPAPPNWAGPETPPGWRGP PPPPPPGGMGHRPGMPPPPP----------------RNFGIGQDIQPKRKLNRFVRWPKY IRLQRQKAVLLQRLKVPPPINQFRTAIDRQTATQLFKLLDKYRAETRQAKKQRLAARSEA RVAGKADKPTDRVPMVRAGVNTVTKLVEQKKAQLVVIAHDVEPLEMVLFLPALCRKMGVP Y----------------------------------------------------------- -------------------MRYVAAYLLAVLGGNESPSSSDIKSILSSVGIEADDKQLKL VVDNLKGKNVDELIEEGMGKLASMPSGGGGGGAEAPKEEESDDDMGFDLF---------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------FNVINGGSHAGNXLAMQEFMILPTGASSFTEAMRMGSETYHHL KAVIKKKYGQDACNVGDEGGFAPNILDNFEALNLLMEAIDKAGYTGKIQIGMDVAASEFC KKYDLNFKDKASDPSTYLSSDKLADVYKDMVAKYPIVSIEDAFDQDDWSAWSALTAIQIV GDDLTVTNPKRVQQAVDQKACNCLLLKVNQIGSVTEAINACLLAQQNGWGVMVSHRSGD- -------------------------------------------------------XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXDDFRQKWDREKYEKLAEERLKELESSDEPPVKRALLKARDYTVDLEG KLGKSQVITKTTPSAGQGGYYCNVCDCVVKDSINYLDHINGKXHQRNLGMSMKVERSSLE QVKARFELNKRKQEEKKSEYDFNERMKELQEEEK-------------------------- --------------MGCAASSEDRQAQERSKQLDRMLRADGEKAAREVKLLLLGAGESGK STIVKQMKIXHDKGYTNEEXLQYRPVVYSNTIQSMIAIIRAMGQLKIDFGHTERADDARQ LFALAGNADEGE-MSIDLSSVMKRLWKDPGVQHCFSRSREYQLNDSAAYYLNALDRISQS GYTPTEQDVLRTRIKTTGIVETHFTFKDLHFKMFDXGGQRSERKKWIHCFEGVTAIILXV AMSEYDLTLAEDQEMNRMMESMKLFDSICNNKWFTETSEDKIKKSPLTVCYPEYAGANSF EEAAAYIQIQFENLNKKKTKEIYTHFTCATDTTNVQFVFDAVTDVIIKNNLKDCGLFYHS QFVEPPRLVGNMALAPLRTQFNGPAYDAIDEALYFFKANIFFKNYEIKNEADRTLIYITL YISECXEKLQKCSSKNQGLKEMHTLAVSQWPLPGDASLERDV--PGTSDRNVEDTMRKFM QQLRQEIGVRVCEKVFDPATDKPSKWWMCFVRRKFMDKSLSARG---------------- ------------------------------------------------------------ -----------------------------TDARNLTNPNTVKFXNGNKSDLDAQRDVTYE EAKQFADENGLLFLECSAKTGDNVEDAFLDTAKKIYQNIQDGSLDLNAAESGVQHKPTAP RNSVQTDQPPQKEGCACMSVKAVCVLKDGEVTGTIHFAQNG-CTLTGEIIGLAPGEHGFH VHQFGDNTNGCTSAGPHFNPHGKTHGAPGDEERHVGDLGNVTADVVNITDQQVTLTGPLS VVGRTMVIHADIDDLGKGGHELSPTTGNAGARLACGVIGICKMVNFTIDQIREIMDIKTN IRNMSVIAHVDHGKSTLTDSLVSKAGIISSAKAGEQRFTDTRQDEQDRCITIKSTAISMY YELSKKDLSHGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQA IAERIKPVLFMNKLDLAILTLQMGAEDMYQTFQRIIENVNVIVSTYCEEDGPMGDIQVSP ATGTVGFGSGLHGWAFTLKQFAEMYSSKFGIDEKKLMRKLWGDSFYNGRRAFCQFILDTI LKVFSTTMTKEDAHKLIEKMGVKLTGDDKDLIGKPLMKLVMRKWLPAGDAMLQMITMYLP SPVTSQKYRIELLYEGPNDDEIAVSMKTCNPKGPVMMYVSKMVPTSDKGRFYAFGRVFSG TIATGQKCRIMGPNYVPEKSIQRTILMMGRYIEPIEDVPCGNIVGLVGVDQYLVKTGTIT TFKDAHNMKVMKFSVSPVVRVAVECKNPSDLPKLVEGLKRLAKSDPMVQCCIEESGEHII AGAGELHLEICLKDLEEDHAGIPLKKSDPVVSYRETVTENSDKTCLSKSPNKHNRLFMTA SPMHSDLPDAIEKGDINPRQDPKERAKILAEKFDMDVNDVRKIWCFGPDGTGANMVVDVT RAVQYLNEIKDSVVAGFQWATKEGVLCEENMRGVRFNIHDVTLHADAIHRGGGQIIPTTR RCLYACQLTAQPSMMEPVYLVEMQCPSAAAGGIYGVLNKRRGIPIGSEPLTGNQE-VVKA FLPVNESFGFTSALRAATGGQAFPQCVFDHWQTMVVVATRQRKGLKEGIPALDNYMDKLM LPLSLLRTAVNHPMLVELKNGETYNGHLVNCDNWMNINLREVICTSREGDKFWKMPECYI RGSTIKYLRIPDEIIDMVKEEAQ-RPRGDGRGR---RGG--------------------- ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXX--------------KTVMQLCHDRGYLVTQDELDQTEDQFKMQFGDKP SERRPSRSDLTILVAHNDDPTDQMFVFFPEELKIGIKTIRTYTTRMQEESITRAIIVVIQ GMTPSAKQSLTELAPKYMLEQFLESELVVNITEHSLVPE--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------FIDEPTAAAIAYGLNKKEGEKNI LVFDLGGGTFDVXLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDIRT DNRATQKLRREVEKAKRALSAAHQTRVEIESFFDGEDFSETLTRARFEELNMDLFRSTMK PVKKVMEDADLTKKDIDEIVLVGGSTRIPKVQQLVKEFFDGKEPSRGINPDEAVAYGAAV QGGVLSGDEETGDIVLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQIFSTAADNQPT VTIQVFEGERPMTKDNHLLGKFDLTGIPPAPRGVPQIEVTFEIDVNGILKVSAEDKGTGS KEQITINNDQNRLSPEDIEKMINDAEKYSDEDKKVKEKVEARNELESYAYSLKNQVGDKE KLGGKLSDEDKTAVEEAVDKSIKWLDSNSDADTEELKAQKKELEEAVQPIISKIY--APP PGEDSEHDEL-------------------------------------SPEEKKEVDARSI YVGNVDYGATAEELESHFHGCGSINRVTINCDKYSGHPKGYAYIEFTDTESVETAQALDD SLFRGRQIKVVSKRTNIPGHSSXNRPPRGRGRRSRG------------------------ ----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXPKVGINGFGRIGRLVLRAALLKVEVVAVNDPFIDLDYMVYMFKYDSTHGA YPGEVKLVVDGKSMEVFAERDPTKIPWGKTGAEYVVESTGVFTTKEKASAHFTGGAKKVI ISAPSADAPMYVMGVNEKSYSKDDTVVSNASCTTNCLAPVAKVINDKFGILEGLMTTIHA VTATQKCVDGPSGKNWRDGRGAYQNIIPAATGAAKAVGKVIPELNGKLTGMAFRVPVPDV SVVDLTCRLSKEATYDQIKAAIKGSMKGILGYTEDQVVSQDFRGDVRSSIFDAAAGIQLS PTFVKLVSWYDNEFGYSCRVVDLINHMNKVDEADLATAILRTKSKPNRLLVEEAINDDNS VVSMSQEKMDELQLFRGDTVLLKGKRRRETVCLVLSDDTVSSEKXRMNRCVRNNLRVRLG DIVSVQACPDIKYGQRIHVLPIDDTIEGLTGNLFEVFLKPYFLEAYRPLKKGDIFVARGG MRAVEFKVVETDPAPYCIVAPDTVIHSEGEPVKREEEEEQLNEVGYDDIGGCRKQLAQIK EMVELPLRHPQLFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGLSSF-SSTAEIMSK LAGESESNLRKAFEEAERTHLPLSSLMTLDAIAPRGXKTHGEVERRIVSQLLTLMDGLKQ RAHVIVMAATNRPNSIDGALRRFGRFDREVDIGIPDAVGRLEILRIHTKNM--------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------KGPELFNKWVGESERSVRELFRKARNAAPSIIFFD EIDAISVERKSQKSGGSGVGDRVLAQLLIELDGVEGNKAVTVVAATNRPDMIDKALLRPG RLNRLLYVPLPDASAREKIFKIRLESAPLADDVSYKELVESTEMYSGAEIVNVCNEAALI AMK--------------------------------------------------------- --------------------------NPNKDIVVASPPEDSISSLAWSPTGL---FLCAG SWNNTVRCWEVQQTGQTVPKAEQSHTHPILDVAWSDDGTKIFTASCDKTAKMWDLATNQA TQIAQHDAPIKAVHWIK------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ASAKTKEGVQTAFEELVEKILQTPGLWESNGVS LSE-------------------------------------CPLANSQYATVKEEKGVIYL YMKTVERAAFPNKLWQKVKLSKNLEKAMKQIDEHLIYWPKYIIHKSKQRLLRISQYLVRM RKLVLKRQKKLVPLGTKVERRETRREAKALIAARLDNAIESELXERLKKGTYGDIYNFPQ MAFSKALEQEEVE----------------------------QVRLTQEKRLKAFSIYRWD PEKPGDKPRMQKYEVDLNDCGPMVLDALVKIKNEIDPTLTFRRSCREGXCGSCSMNIGGT NTLACLCKIDANTSKATKIYPLPHMYVVKDIVPDMGNFYAQYMAIEPFLKKRGVEQSDVG KESYLQSQEDRAKLDGLYECILCACCSTSCPSYWWNQDKYLGPAVLMQAYRWIIDSRDDY RKERLPE----------------------------------------------------- ------------------------------------------------------------ -------------RISYSKTDSDVIAKIEGHICTQRERSQTEIPKKKKKKATPAVIPEQP PNQILFLTNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENETQS-------- -----------------MDSQGKKIVVCDNGTGFVKCGFAGANFPAHIFPXLVGRPVIRA TTQVGDIQIKDLMVGDDASKLRSMLEVNYPMENGIVRNWEDMLHVWDYTFGEEKLNINPK DCKILLTEPPMNPSXNREKMIEVMFEKYGFEGVYIAIQAVLTLYAQGLLTGVVVDSGDGV THICPVYEGFALXHLTKRLDIAGRDITRYLIKLLLLRGYAFNHSADFETIRMXKEQLAYV AYDYRARREIA------------------------------------------------- ---------TRPEFYKHIVLSEGPTMYPGXPSRLEREIKQLYLERVLKGDTQKLSKFKIR IEDPPGRKHMVFLGGAVLADIMKDKDSFWISKKEYQEKGMRCLEKL--------GQVITC KAAVAWEPKKPLSIETIEVAPPKAGEVRVKILATGVCHTDSFTLDGHDSEGKFPVILGHE GGGIVESVGEGVTDYAPGDHVIPLYTAQCYNCKFCESKKTNLCQKIRGTQGQGLMPDGTT RFTCKGKEVFHYMGCSTFAQYTVVAEISLAKVDPAAPLDKVCLLGXGVTTGYGAAINTAG VEPGSTCAVWGLGAVGLATLMGCKAAGASRIIGVDINPAKFETAKKFGATECINPKDYNK PIQEVLVALTDGGLDYTFEAVGNVATMRAALESGHKGWGVSVIIGVAPAGTEISTRPFQL VTGGXWKGTAFGGYKSRDSVPKLVDMYMKKELMVDEFVTFNLPLDKINEGF--------M ETYDVIANQPIVIDNGSGIIKAGFAGDTIPKHCFANYVGRPKHTRVMAGALEGDIFIGPK AEEYRGLLHIKYPMEHGIVEDWSDMERVWQYIYSKEQLQTFSEEHPVLLTEAPLNPXRNQ EKAAEIFFETFNVPALYISMQAVLSLYAAGRTTGVVLDMGDGVTNSVPIYEGFALKHSIV RTDIAGRDVTRYLKM--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------KLKKVVVHPLVLLSVVDHFNRMGKVGNXKRVCGLLLGSSRQG VLDVSNSFALPFDEDEKDSSVWFLDHDYLENMYSMFKKXNAREKVVGWYHTGPKL----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------MGFLFSKLWSMFSNEEHKVIIVGLDNAGKTTILYQFLMNEVVHTSPTIGSNV EEVVWKNIRFLMWDIGGQESLRASWTTY-STTRSLHSVVDXTDRGTLSVTKEELYRML-- ------------------------------------------------------------ ------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRSFSVSAKVA VLGAAGGIGQPLSLLLKLNPLVSHLSLFDIVHTPGVAADLSHMCTPAHVTGHMGTDQLEA CLSGSNIVVIPAGVPRKPGMTRDDLFNTNASIVRDLVDACAKFCPESMICIISNPVNSTV PIASEVMKQRGVYDHRRVFGVTTLDVVRANTFVAEAKDRDVAHVNVPVIGGHSG------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------MFVGPTYYQRLKHMVDDKIHSRARGPLQILNRQPMEG RSRDGGLRFGEMERDCQIAHGAAQFLRERLFEVSDPYRVHVCNLCGLMCIANLRNQTYEC KGCKNKTQVSQVCMPYACKLLFQELMSMSIAPRMM------------------------- -------------------------------DTVVADKNCSKIHYMAPNIYCCGAGTAAD TEYTTNMVAAQLELHSLNTGRVSRVTSACQLLKQYLFRYQGHIGAALVLGGVDPTGPKLS IIYPHGSSDSVPYGTMGSGSLAAMAVFENGYKPNMEVEPAKKLVRDAIAAGIFNDLGSGS YIDLCVITKGVDYIRPYDKANLKERGKGTTKYKSGTT---------------XXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXX--FHLCSFFYILALILSAVLIFFAIYHIIAFDELKTDYKNPIDQ CNTLNPLVLPEYAIHIFFNILFLFAGQFGSLALNIPLIAYHVHRYITRPVMSGPGLYDPT TVMNADSLSRCMKEGWVKLAFYLISFFYYLYSMIYVLVTSXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHSKKKVCYYYDGDIGN YYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPMKASVEEMTKFHSDDYIKFLRTIRP DNMSEHNKHMQRFNVGEDCPVFDGMYEFCQLSGGGSIAGAVKLNKLQTDIAVNWAGGLHH AK---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------MLPHAPGVQM ANIPEDALTTDENPDERMSIRASDKRIACDEDLSDSEDEG-DGRKDEQNYKTAKRTNGTY DCNICLDIAKDTVVTFCGHLFCWPCLHQWLSTRPDRQMCPVCKAGISKXKVIPIYGRGST DNKDPREKLPPRPSAQRSEPENNSSFGNFNM-LQFSFGIGAFPFTFFASNFNLGDARPGN PSAGTQQHQEERVLSQIFLFVAMFLLYGL---XXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXX----EIDKEIVTYLARTDIDSWQLRKTLQTI HTRDAIPDPNIITAVLKACRHQNDFPLALRFLETVQLKCGPHKKVVWPWLVQQIKPTLDD LGVPTPEEIGYDKPELYLEDVMDMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------IGCK PIASLDHFTADMLGSAELVEEMHAGSSKIVKVTGVQNPGRVVSVIVRGSNKLVLEEAERS IHDALCVIRCLVKKRALIAGGGAPETELSIRLREHADTLSSMQQYCFRAYADALEVVPFT LAENAGLNPIATVTELRNRHANGEIHTGINVRKGMITNILDENVVQPLLVSTSAITLASE TVRSIMKIDDIVNVMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX- --FCPTCANILIVENFSSTVRLACSTCPYVHDVXKKITRRTYPKLKEVDDVLGGADAWKN VDSTDETCPKCSNSRAYFMQVQTRSADEPMTTYYKCCNHECGFRW-KTKFGPLKDEDRIF TNLYGRHDWKLKGAMSRGQWYKTKEIVLKGPEWIQGEVKESGLRGRGGAGFPTGLKWSFM NKPDDGRPKYLVVNADEGEPGTCKDREIMRHDPHTLVEGCLVAGRAMGARAAYIYIRGEF YNEASNMQVAINEAYKAGFIGKDACGSGYDFDVYLHRGAGAYICGEETALIESLEGKAGK PXTQTPFPADIGVFGCPTTVANVETVAVAPAICRRGGSWFASMGRERNRTVLMDFDGLVE AQTSLGTAAVIVMNKQCDIVRCISRLIDFYKHESCGQCTPCREGVSWMMKVMHRFTTGQA KPSEIDSLYELSKQIEGHTICALGDGAAWPVQGLIRHFRPVLEQRMRDFEAKQ------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------VSANLTCNNQRNKIITCQ AGGIEALVRTILQAGDREDITEPAVCALRHLTSRHPEAEVAQNAVRLHYGLPVLVKLLHP PSRWPLIKAVVGLIRNLALCPANHAPLREHGALPRIVQLLIRAHQDTQRSSGSIVDGVRM EEIVDGTVGALHILAREHNNRGVIRGLNCIPLFVQLLYSPIESIQRVAAGVLCELAADKE GAEVIEEKGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELSSSLHF-- PVSSALQWSVIRKSSCFLIKRNNYTKEPSNLRGVNSYRYNGLVQEKTVGVEASADGKGVT LVTKKNRNKPVKSHTRIPLKKNSRRAFKTIMKTLKGQGYRKDLQAPALRRASTILRTQK- -------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------PTKERIVK TVPLPPSKRLTVADVYDSKGKPRPDVLKQHFVLEGRLSNECALKIINDGTALLRAEXTMI DIEAPVTVCGDIHGQFXDLMKLFEVGGXSASTRYLFLGD--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------GSRGGFRSDRGG--RGRGGFGGGKRVIVEPHRHKGVFIARGKEDVLV TLNQVVGESVYGEKRMSVEQGTKIEYRVWNPFRSKLAAAIMGGVDNIHIKPGAK------ ------------------------------------------IPIIEDARHPHKYRMLVS SVDCIFADVAQPDQARIVAINAHYFLKNEGFVVISIKANCIDSTAESEAVFASEVNKLKN EK----------------------------------MEDIGGRLARGGKGAGVGVGLIGA IGAAAAAIYQAVYTVEGGHRAVMFNRISGVQKDIYKEGIHFRVPWFQYPIIYDIRAKPRK IVSPTGSKDLQMVNIGLRVLARPDQSALPHIYQQLGTDYDDRVLPSIINEVLKGVVAKFN ASQLITQRQQVSLLIRRDLVNRAKDFNIILDDVSITDLSFSREYTAAVEAKQVAQQEAQR AHFFVERARQEKQQKVVQAEGEATAAKMIGEAVKENPGYLKLRKIRAAQHIAKTLTNSQN KVYLNASTLMLNINEKEFDQSVDSYTDESSDEDDHSPRDHHQINSSGFNDFCVRIKQAAF GRREIEIAEQEMSGLMTLRQRAEDDKPLKGAKIVACTHVTAQTAVLMETLISLGASVRWA ACNIYSTQNEVASAVAEAGTPVFAWKGETEDEXWWCIEKAVCAEGWVPTLILDDGGMAT- ----------------LEESVTGVHRLYQLSKMGKLLVPAMNINDSVTKTKFDNLYLCKE SIVDALKRTTDVMFGGKLVLVCGYGEVGKGCCSAXKGLGCIVNVTEIDPICALQACMDGF KVVRMSETVRSADIIVTCTGNKNVVTREHLDKLKNGCXVCNMGHSNXEIDVXSLRTPELT WEKVR------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------GCAFVTYTARDSAITAIRSMHHSVTMEGCSSPMVVKFADTQKDKD----- ---------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------- -----------NASALERQDSKIGTSDDGPELRDKLHEIQAETNGIATQISEMIQNLQR- ARGDRQKRLHVERLKTSFKSALDRYSNIQQRVKNQLKGESVEDEYDLAREREERMRQLEA DVLNVNDIFRELGTMVVEQGEQIDDIEANVVHDNVSEGNVQLEKAAAYQKSYRKKLCILA IILVVV-------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXSKKKGEAPSPQEAIQRLREVQEMLTKKSDFXRE KVEHELATAKKRVALAALKRKKRYEKQLQQIDGTLSTIEFQTEALENANTNTEVLKVMRT AGQALKGAHQNLDVDQVHDIMDDLAEQHEIANEVSEAISAPVGFGHDYDEDELNEELEAL EEEELVSQIVGIDGLPSVPTSSDDEMAELNAWAA-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------EIRCVVMPPQWGTHQTVHLPNYLPSHEYLKEMEPXGWIHTQPNELP QLSPQDITTHAKIMSDNPSWDGEKTVVITCSFTPGSCSLTAYKLTPSGFEWGRQNTDRGN NPKGYLPSHYERVQMLLSDRFLGYFMVPIQGSWNYNFMGVRHEANMKYELMLSNPKDFYH EVHRPSHFMNFTSI---------------------------------------------- -----MVGGTSRAKVGSSHLGLPVFDTXNQAKDATXCDASVIYVPPKFAAAAIVEAIDAE IGLXVAITEGIPQQDMVRVKHKLLRQNKTRLIGPNCPGIIRPGECKIGIMPGHIHQAGRI GIVSRSGTLTYEAVHQTTHAGLGQTLCVGIGGDPFNGTNFIDCLEVFLADPKTEGIVLIG EIGGQAEERAAEYLVAHNGPDAKPVAAFIAGLTAPPGRRMGHAGAIIAGGKGGATEKIXA LEHANVHVTMNPAEMGTTMVEAMKAAGK-NYDVMKCFLCCSQLEDTHFVQCPAVQEHKFC FPCSKDSIKQQGVKNEVFCPSGKRCRLSSSTVPW------------YEKFVEIGRVAFVS AGPSKGKLAVIVDVLDQNRALVDGPCSGVARHVANFKALQLTKYVVVGPGARTGTVTKAW TKADITSKWAETSWAKRQEAMAARAVMNDFDRFKLMKAKQARRGMQSQLYGKANKILKEV CPFLLRVFTNTGRPYHISEFSRGNLPPNQVSIYTWMDATLKELAGLIKQMNPDARRKGTF IDFYVVFP---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ERRVNFNVDAYFREALRV SEPKAPKAPRPPNNQTFRTFSFXPPRLFELLDREIYHFRKTLNYKVPLNPDLGADAERQQ QEQQELIDSAELLTDAEVAEKEGLLNGFTSWNKRDFNQFIKANEKYGRDDLESISKDVEG KTPEEVMQYANVFWDRCNELQDIDKIMTQIEKGEQKIQRRISIKKALDCKMTRYKAPFHQ LRIXYGTNXGKNYTEEEDRYIVCMLHKLGFDXENIYDELRAXVRQDPQFRFXWFIKSRTA MELQRRXNTLITLIERENTELEEREK-----DVKPSWADQVEEGENVELPPRSETFDKNT GTRTVTEYKLNDDKKKVKVVKTYKTEIRKVSKSIAKRKTWKKFGEAAQDPPGPNPANTIE DIQMQFVHTKEATEANPLAALQVQCRICKGDHWTTKCPYKDTLGTLQESLKTGGRYVPPS MRGGAAKEGESMQMDDHATIRVTNLSEDTVEEDLQELFRPFGNISRIYLAKDKNTGASKG FAFINFVRKEDAARAIQGVSGFGYDHLILKVEWAKPS----------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----LETSAMTGENIEETFLKCGRSILAKIESGDLDPERMGSGIQYGDASLRRAQANKPS CSC--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------DAQWVYD NHKDESYLRRVIQPVEYLLVSHKRVVIKDSAVNAICYGAKVMLPGVLRYEDGIDINEQIV LITTKGEAIAIAIALMTS------------------------------------------ ------------------------------------------------------------ --------------------------------KQSSAAKNTAKLDRETEEXHHEHVALSL SRLIQKCRQDKEMIQKELATKINEKPQVINEYESGKAIPNQQVISKLERCLGVKLRGKDI GQ-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXX-----------KTLADAYAVPANFLEIDVCDAQANKRYTDYEVRLKTN LPIFRVKESSVRRRYSDFEWLKKELDRDSKIVVPALPGKAFKKQLPMRSDDGIFEDDFIE ERRKGLEQFINKVAGHPLAQNEKCLHIFLQDAEIDKNYVPGKVRTT-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------RYWHITDQNGQVDEVYGPGVVGEQPHLNPGD-SYEYSSGCPLDTPSGL MFGHYEMETDKGEVFNVTIPAFSLDS-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXMDIFLMIRRKKTTIFTDCKETTTVVELKKIIEGITKVLPED IMLFNFKKNLQDNGYTAATARAQSPAQVGLVYREFEALDITAYSVPPELPDVMKAQE--- -----HRFRYHVVLLRDRFDQNAHIDVREAKKILVEGEKELWEKHYPSRIRFGESPGGAA FNRTKYIPDWVLDTWHPYEKAAFPEYFARREIRKKEYLERWENKYGQ--XXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--KLANNLTRVGIGLAVGGAVINSALY NVDGGHRAVIFDRLSGVSQKVKGEGTHFLIPLVQTPYIFDVRSKPTNVPVVTGSKDLQNV SITLRILFRPEASSLPNIFVNLGIDYDEKVLPSITREVLTAVVAQFDASELITQREIVSQ RVNDELTERAAQFGLILDDISLTHLTFGQEFTSAVXQKQVAQQDAERARYLVEKAEQVKQ AAVITAEGDSLGAKLIASSLAGAGEGLIELRRLKQLETL--------------------- ---MKTIHCVQDIPIPENCKFFVKSRKVTVTGPRGTIKRNFGHLQIDIRVIGKNTIRVEK WFSNKKEMAAVNTVCSHIQNLFTGVQRGYRYKMKSVYAHFPINIAISEAGRKVEIRNFLG EKYTRIVMMPEGVT-AANTGSKDEYQIDGNDIDAVSQAAARIQQSTSVKNKDIRKFLDGV YVSEKLNIEQ-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXMSFNSDEVNFLIYRYLLESGFSHSAYTFGIESHISQSNINGALVPPAAL LNIIQRGLFYTEAEISIAEDGSGRVIESLSLIDAVMPDVVESRKVAAAKNGSQEV-AADM EIDAAIEIPDSRTTVLRGHESEVXICAWNPKNDILASGSGDSTARIWNMNEMASANQLVL RHCIQMGDAEVPSNKDVTSLDWNCDGTLLATGSYDGYAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --QLIGTRKAAENFAYRLELNDF-RAVDMEATPRSIHDGVQSAIQNSDCLVFDTNIARLF ADNGNLGINVTISMCXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XX---VINDNGLRIDGRSSSDSRPIFLETGFVTRSKGSSYIEIGNTKVICACYGPKH--- CKAKXRKGVLSCELKYASFASAVHKTD-QANMLEKEYSVLMVDALSPCIILDRFPKAQVD I-LNYLEDGGSAFPAAITAASLALADAGIELYSL-------------------------- ---------------------------------------------------XXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXX--QRRYVHTDVKFPDFGAYKKSD--EKQEVFSYLMIGGAGAPMVYGGKS MVTKFISAMSAAADVRALAKIEINLDDIPEGKNMVFKWRGKPLFVRHRVQEEIDAVRDVN VSELRDPCPDEERVQEDNWLVIIGICTHLGCVPIANAGDYGGYYCPCHGSHYDASGRIRK GPAPLNLEIPEYKIND-NLLVVGMSRPS-KPGDPRKVSTELFTLTYGALVTQLIKDYEDE QEVNKQLEKMGYNIGIRLIEDFXARSNTGRCNDFRETAETIAKVGFRMFLNIAPVVTNWS PSGDTFSLLLDPNPLTEFVELPE-DKKLNYSNILCGVIRGXLEMVQLEVQAWXVSDQLKG DSSTEMRV---------------EQVKVFLAERSWSLKANGKAPEKNTACLDDFDRIKTL GTGSFGRVMLVQHKPSRSFYAMKILDKTKVVKLKQVEHTLNEKKILQAINFPFLVSLEYH FKDNSNLYMILEFVPGGEMFSHLRKIGXLAKFTRGFYASQIVLAFEYLHHLDXXTRDLKP ETLLV------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXX----------------------------------- -----------------------------------------YYRGAMGIMLVYDITNEKS FDNIKNWIRNIEEHASSDVEKMVLGNKCDMNDRRQVTKEKGEQLAVEFGIKFMETSAKAS INVDEAFISLARDIKVKMDRKL-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----KRLIGKYFDEISQDTGRYCFGVNDTLKSLEMGAVEILIVWENLEVTRYVLKDHSTD SDTKLFLRPEQEKDKTNFIDKETGVELEVIDSMPLLEWFANHYKEFGATLEIITDRSQEG AQFVRGFGGIGGILRYQVDLQQLEELEEGFEDFDLDDYXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXX----------------------------------------------- ---------------------------------------------TMITGHNVADVVIIL RTLPTREAVIALGQRVLSDIRAATA-ETISLVPNDKGFNISNSEATVKCLISTIPPNLPK LEPDLHLPTKVMTDHLAAIRHVRWFDENAGHVSIKVLIRLLKDLKVRYTGMQCLSPWLID LXAHHAIMSNPSRTPLSTNLAF-RALALLASGIFLPGSIGILDPCEIGNGRAHVQMPLEQ MDLLCCTGQTLTRILAHGGYKQILQLEGVTDVVNTVTQW-GVSLSP-------------- ------------------------------------------------------------ --------------------RSLLRQTDPMIMLKQTQADRYVHLENMLARSYFDPREGYP EGQSKEKRRAAIAQALSTEVHVVPPSRLLSLLGQALKWQQHQGLLPPGTTIDVFRGKAAV REQEDEKCPTMLSKTIKFGQKSHIESARFSPDGQYLITGSVDGFIE-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXX--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------P GKHYLDQLNHILGVLGSPSQEDLNCIINDKARGYLQSLPYKPKLPWERLADSSVLDLLDK MLTFNPHKRITVEEALAHPYVEQYYDPADEPVATEPFTFATELDDLPKEQLKELIFEETQ KIKNR------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------PAISLAYERAESDIMKRLPRDPQHDRLVNERLISMAYGQI GMMQASAGFFVYFVIMGENGFLPVRLIGLRKEWDSKAVNDLEDSYGQEWTYYQRKTLEYT CHTAFFTTIVVVQWADLIICKTRKNSLLHQGMINWQLNFGLWFETALACFLAYCPGLDNG LRMFPLRITWWFPALPFSLLIFVYDEIRRYILR-------------------------FG VAA--LTVYNLEKELLLHPPAYEWAHNKVFGSFDAASLRRGYLVYKNVCKQCHSIKYLAF REMVGVFMTEEEAKAEAAEVDIVDGPDDTGEMFERPGKLSDKLPMPYRNDEEARFANNGA LPPDLSYIVLARHGGEDYVFSLLTGYCDPPEGFDLKDGLHYNPYFAGGAIGMAQALFPGI YEYADGTPAPVSQLAKDVTEFLAWIAQPELNTRKEMAIKFLMVMLLPSVYYWKRFKWAPI KNLKIEWVRPDLPSKCTWKPG-KDKDPHTHXPXTPKVMKNILDAIGNTPLVQLNSIPAEX GVKCRVLAKCEFXNAGGSVKDRVALRMVENAEKAGILKPGSTIIEPTSGNTGVGLALAAA VKGYRCIIVMPEKMSSEKVNILKALGAEIVRTPTSASFEDPESHIXVAWRLKNEIPNSHI LDQYRNSGNPLAHYDTTGEEILEACGGKVDMVVLTAGTGGTVTGIGRKIRDKCPNCKIIG VDPEGSIIAQPSDVTMYEVEGIGYDFVPTVCDVRVVDKWYKSGDKSSLNMARRLIKSEGL LCGGSSGAVTYMAMQACKDFGLTEDQTCVVLLPDSIRNYMTKHLSDDWMLARNF-----S DEENGPYLGEYEGERNDKEERHGQGKATLPNGDTYEGQYDSGKRHGHGTYRFKQGARYIG EYAKNXKTWSGNVYYPDGSKYEGSWVDDQRCGFGKYSYINGDYYEGEWQNHVRHGQGTYY WAETGSKYVGTWKEGRMEGAGELVHANHKYVGXFKENRPDSKGKYVFDIGCQQHGNY-XX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX--SSLKFELPANGKRCLKEEIHKHALVKGDYELSDVHGHHTTV KITDARDHSFFSNDNNLNGVFAFSVEEYDLFEICFINKLEPGGDSRPRIVTLNIKHGNEM KDYDALAKAEKLKPLEKELRKLEDLSESIVNDFAYMRSREEEMRDTNESTHSRVLYFSVF SLLCLVGLATWQVFYLRRYFKSKKLIDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------- ------------------------------------------------------------ --------------------------IPTEAQTKAISKEWADRADVPTHVVTMLNNFPAT VHPMAQLSAACNALSTESLFSKAYADGVKKSEYWQYAYEDSMNLIAKLPTVASIIYRNLY RDG-KVAPIDPDLDWSANFVKMLGYDNKDFTELMRLYLTIHTDHEGGNVSAHTCHLVGSA LSDPYLSFAASMNGLAGPLHGLANQEVLIWLNKVHFTDDELKEFVWETLKTG-VIPGYGH AVLRKTDPRYMVQREFALKHLPDDPMFHLVSQLYNIVPDVLREHGKAANPWPNVDAHSGV LLQYYGMTEMNYYTVLFGVSRALGVLSSLIWDRALGLPLKRPKSMSTEGLKKLV-MPFKP PVLEKCKSCGKSVYSAEERLAGGHKWHNFCFKCGLCGKMLDNTTYSTKEEKVYCRVCYGK KL---------LFVHRDSPENNSNTKFEFTPENLKRAETIISNYPKGHEAAACLPLLDLA QRQNNWLPISAMNYVAKLLGMANMRVYEVATFYTMYNRQPVGKYHVQICTTTPCMLGGVG SDVIMETIQKKLKLSLGXTTPDNMFTLSEVECLGACVNAPMIQVNDDYYEDLTVEDTNK- -------------------------------------------------EKFQKLEKIGE GTYGVVYKAKDRQTGEVVAMKKIRLDTESEGVPSTAIREISLLKELDHPKVVRLLDVIQT DQKLYLVFEFLNNDLKKFMDSHTGLLPMELVKSYCYQLLQGIAYCHAHRVLHRDLKPQNL LID--------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------XXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSLSTIPKDLRRLRACLLCSLVKTVDQFEMD GCDNCEKYLNMKNRIDSVDEYTSQNFDGMTA----------------------------- -----------------------MPEFYQYLSAAQEQELASIAQQIVQPGKGILAADEST GTIGKRFANINVENVEENRRAYRQLLFTSISDHISGVILYHETFFQKADDGQSLLIXLKN LGIVPGIKVDKGVVPLAGTDDECTTQGLDGLAERCAEYKXEGAGFAKWRCVLKIKSHGPS HQAMIENANVLARYASICQQNGLVPIVEPEVLPDGDHD---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------PLLEHLTNVKVQFSMGFTLEFHFSPNEYFTDKVLTKSYEMRAEPDEED PFSFEGPEIVACQGCVINWNKGKNVTVRVIKKXTKHQKSGTTQTITKEEQQDSFFNFFTP PAPELDEIDHETEALLQADYEIGHFIRERIVPRAVLFYTGEACEDEDYEDDDEDDIILLK EGTDSSQGKPQLISNINACQHIVDAVRTTLGPRGMDKLICIGN-KATISNDGATIMKLLD IVHPAAKTLVDIAKSQDAEVGDGTTSVVLLAGELMKMCKSFVEDGVHPQVIVRATERLTK HGMEKIKELAVKISTDETEKRKLLERCAATALSSKLVAHQKDFFAKMVVDAVMCLDHLLP LNMIGKEKVQDGALEDSMLVQGVAFKKAFSYAGFEMQQKKYSQPKIAMLNVELELKAERD NAEVRVDNVQEYQSVVDAEWDILYDKLKKLYESGAKVVLSKLPIGDVATQYFADNDMFCA GRVPDEDLKRTMKACGGSIQTTVANLTLGTCEVFEETQIGGERYNIFKDXSQAKTCTLII RGGSDQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELXKYLREYSRTIAGKEQLL VAAYARALEXIPRQLCENAGFDATNILNKLRQKHSGKWYGVNVMTEDISDNFEGCVWEPS VVKINALTAASEATCLILSVDETIKTPKLIKDAPRGGMGRGR---GNGMLPNMHLRKNWK RWVRTYFDQPMAKKRRATKRAQKARKIAPRPVAGPIRPIVRCPNNRNNHRERLGRGFSLE ELAAAGLNRRWARTVGISVDHRRKNRNVEALQQNVQRLKEYRSKLILFPRKASKPKDGDA SEEEIKMAQQLMGTVMPIDKTVPPMEVRAPTEDEKKFQAYITLRRQWRRAKLQGMREK-- ---MPNIKIFSGTSNPEVAELVANRLGLKLSSVITKKFSNQETCVEIGESVRGEDVYIIQ SGCGEVNDMLMELLIMINACKIASACRVTAVIPCFPYARQDKKDKSPISAKLVANMLSVS GADHIMTMDLHASQIQGFFDIPVDNLYAEP--------NIAEWRTAVVVSPDAGXAKRVT SIADRLNTEFALIHKERKKANEVDSMVLVGDVKDRISILVDDMADTCGTICLACDKLIEA GSTKVYAILTHGILSGXAVSRIAKSNFEAVVVTNTIPQAENMKNCTKIQCIDISAIFAEA IRRTHHGESVSYLFYNTPILSCRFYQHKFPEQEDVVMVKVRDIAEMGAYVHLLEYNNIEG MVLLSELSRRRIRSINKLIRIGRDECVVVIRVDKDKGYIDLSKRRVGQEDIVKCTEKYSN AKHVNSILRHVAELLEYQTNEELEELYEKTAWHFDKKYGKPGASFEAFKHAVIEPEILNE CDIDEKTKEVLLADIRRRLTPQAVKIRTDIEVSCYHYEGIDAVKAALKAGLVVSTEEMAV KINLIAPPTYVMTTTTLERDGGMARGHQKEQSKQKNAKKNEQLAADQKKAAAAALTYSCT VCRSQMGDPKTYKQHFESKHPKAPLPEQLKGVXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------- ------------------------------------------------------------ ------------------------------------------------------------ -VVFEQTEAKDWSKVVLAYEPVWAIGTGKVATPDQAQEVHSDLRKWLSDNLSVDVALSTR IIYGGSVNAANCKDLAKQPDIDGFLVGGASLKPEFSEIINAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------LEQQLAKLK QYEQNVQSYKSNIEDLEHLNQEVQEAMIFENRHTSYTMETLRVGWEQLLTSIARCINEVE NQILTRDSKGITNEQLEEFKKSFNHFDKNRSRQLEPKEFKACLVSLGYNIRDDRQGEADF QRIMSIVDPNGTGYVTFAAFLDFMTRETADTDTAEQVMQSFRILAGDQEFITADILRREL PPDQAEYCIARMAPYRGANANPGALDYTSFSTALYGESDLNKLSVDGVELKDQRVLIRVD FNVPLKESTITNNQRIVAAVPTIQHALDSGAKSVVLMSHLGRPDGKRQEKYSLKPVAAEL EKLLSRKVNMLADCVGEEVQAACADPTPGSVILLENLRFHPEEEGSSKDDAGKKVKASPE AVAAFRDSLTRLGDVYVNDAFGTAHRAHSSMVGVICPXRASGFLLKKELAYFARVLRTRR RPFLAILGGAKVKDKIQLIDNMLDK-------------FLKVLQGMKIGSSXYDEEGAEI VPKLMEKAEKNGVKLHLPVDFVTASKFAEDADVGGALC-WCIPDGXLGLDTGKESAKMFT EIISRAKLIVWNGPVGVFEWANFAFGTKTMMDDVVAATMKGVTTIIGGGDTATAAAKWNT EDKVSHVSTGGGASLELLEGKELPGVSALSD-XXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXFRPLMNRVLVQRLAAETKTKGGIMLPEKSLGKVLQGTVVSVGPGSR LDSGTVVPPAVAVGDKVLLPEYGGTKVNLNDEEYTLVRDDDILG---XXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------NGF ELAGRPMKVGHVTEKQEGQDTYDNEELERHGYDLGATGRIALMAKLAEGSGFSLPAAAQN ALDMQMSQPTPPIATQCFMLSNMFDTNTANPNFDVEIRDDVIEECNKHGGVLHIYVDKSS AQGNVYVKCPSIASAVASVNALHGRWFAGKMITAAYVPLPNYHQLFPDATKASQLLMPSS XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXX------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------ATFTRAELQKNVITNSS FKLFLELEPQIRETLNAFYSSKYGVCLKILNDMKDNLLLDIYLARHVNYLYTQIRNRALC QYFSPYVSADMSKMAEAFNTNVGDLENELMQLILDGQINARIDSHNKILYAKDINSR--- -----------------------------------------------------------L ISKAEDLADQVLRQTKHLLPHIAHLCLVGTFIEDGVRMMTQWSEQRDYMDSQWRCGWFLA TLFVLVNLIGQLGGSVLVIARKYVEVACGILLGIILLQTVAYSVLWDFRFLTRNLSLVGG VILLLAESRVEARSSFAGLPSTGENKLKEYLQLGGRLLLVLLFVSILHLDSDLFTIIKTL IGMAFMILVAVGFKTKLCSMILVLWLTSLNLYFNAFWMLDSSTGMYDFLKYDFFQTLSIV GXLLLLVALGPGGVSMDEHKKAWRHTVTLIPGDGVGPELIGYVKEAIRFSGAPVDFEEIG VNRNGVGLKGNVEADDKSKNIAIRKGLDLFANVVRCKSLPSYRTRHSNIDLVVIRENTEG EYSQLEH----------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------SGQVVLWDNRSSKRMPV QRTPLSASAHTHPIYCASVVGTENAHNLITISTDGXVCSWSLDMLSQPQDSMILTXQLIK VAALSMSFLSGDVNNFLIGGEDGAVSSACRHGSKAGVTNSLDGHNGPVTGIDTHCVQGAV DFSHLYLTSSFDWTVKLWSTRNDHELYTFKDGTEYMMDVRWSPIHPALFACVDGSGKLSL WNLNNDTEVP-------------------------------------------------- ------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-T RKQTPSEFLKQIIGRPVVVKLNSGVDYRGVLACLDGYMNIALEQSEEYVNGQL------- -----------------MTEERGALLLRKQLAELNKSCTEGFSAGLIDDEDIYRWEVVIY GPPDTNYEGGYFKAHL-------------------------------------------- ------------------------------------------------------------ ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXX---------------------------------- ------------------------------------------------------------ ----------------------------------------------------NKFLQPVH KCDMALTDLLQEIQPDPWPVAQGKRPLXSTGAALSIAVGLLECTYPNTGGRIMMFIGGPG SQGPGQVVDDELKNPIRSHHAIEKDNARWMRKAMKHYEALANRSAQNGHVIDLYSCSLDQ TGLHEMKFCCNYTG---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------TDAQAKLL ENLELEMMADMYNRMTSACQKKCVPXKYSDGELSKGEAVCIDRCVAKFMDVHDIVGKKLT AMS------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXX-LKVLITGAAGQIAYXLLYSIAKGDVFGKEQALSLVL LDIPPMMGVLEGVVMELQDCALPLLTEVVATSDEAVAFADIDAAMLVGAMPRREGMERKD LLAANVKIFKSQGAALDKYAKKSVKVVIVGNPANTNALICKKYAPSIPASNFSALTRLDQ NRAQAQLAGKEAVKNVVIWGNHSSTQYPDAKHATAVYEAVQDDNWLNNEFISSVQQRGAA VIKARKLSSAMSAAKAIGDHMRDWWFGT-QSRWVSMGIISDGYGIPEGLIFSFPLTVDRS WKIVDGLDISDFAREKLEKTAKELVEERDMALAACSGGSSSLMVGPNWRVGKKIGNGNFG ELRLGKNMHTNEHVAIKLESMKSRAPQLHLEYKFYRQLGVHDGVPVIHFYGLCGKHNALV LEL--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXDQQLDCALDLMRRLPPQQIEKNXGDLIDIVPHLCEDLLSAVDQPLKIAKD KKXGKDYLLCDYNRDGDXYRSPWSNEYEPPLEEGAMPSDRLRRLEIEANDAFDNYRQLYF XGGVSSVYLWDLESGFAGVVLIKKXGDGSKKIKGCWDSIHVIEVVEKSGGRNAHYKITST VMLWLQTNKESSGSMNLSGSLTRQHELESPVSEATSHVANIGKLVEDLENRMRSTLNEIY FSKTRDIVNSLRSVEPIQQQMLQTDLAAALSKRA--DEDRFDGDDDLDAVP-GLPSEIVP LQERVDPTKRVTTPYMTKYERARILGTRALQISMCAPVMVELEGETDPLAI--------- --------------------------KQTSLKEKLMAPVGNNAFGIGRGVVAGSAALGIG ALCFYGLGMGGDVGVREKSLMWPQYVKDRIKTTYLYFGGXLCVSAVFRTPALLRLVSYQG FMGMLVSLGAMVGTSMLCQSIPYTENAKQLAWILHSATVGAVIAPLCVLGGPLLTRAAMY TAGVVGGLSSIAVCAPNEKFLSWGAPLGMGFGLVFVSSLAGAFXTPTTVLGAGLYSISVY GGLAIFSGFASIDTQK-------------------------------------------- ----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXYEEKAERAVVIA HPMASRKLAKRIFKLGQKACQXGLKIVKKNLQKKMKGYVVLAGDADPLDTVSHFPVLCEE NNTPYVWVPTRRDLGLAVGSGAALC-AFIKPDESYEETYDQVYEKI-------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------GDWDRRNRLKVYKAVY SMANRKFKEAAXVLFDAVATFTSYELMDYSDFIIYTVILGMEALARPDLRDKVVRGAEIL EVLHDQPSTKEYLMSLYDCRYAEFFKSLAGIEQKLQYDRYLHEHYRYYVREMRVLAYTQL LQSYQSLTLNYMAKAFGVTVSFIDQELARFIAAGRLHAKIDKVGXIVETNRPDSKNYQYQ AVIKQG------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------HQAAYLGASLCCIGSLTGLHXQSTARVGNALGIMGVSSG VAATLGLLKPSAEVITQMAATMGXGGLIGTVMAKRIEVTDLPQMVALFHSLVGAAAVLTC FSNFLFEYPHFATDPAANVIKTSLFLGTFIGGVTFTGSLIAFGKLQGLLKSDPMKLPAQN LLNGGMALGNVAAMGAYLNSSDSLMLGMLGSTTALSSVMGVTLTAAIGGADMPVVITVLN SYSGWALCAEGFMMNNNLMTVVGAMIGSSGAILSYIMCVAMNRSLPNVIFGGYGTSSTGT GKPMEITGTHTEVNSDMVVDMIADSKNIIIVPGYGLCVAKXQYPIAELVSLLSKKGKKVR FGIHPVAGRMPGQLNVLLAEAGVPYDVVLEMEEINDDFPETDLVLVIGANDTVNSAAEED PNSIIAGMPVLRVWNSQQVVVMKRSLGVGYAAVDNPIFFKQNTGMLLGDAKKTCDELLAK T----------------------------------------------------------- ---DTCHRQCCGPGRGFVMHLTDNMGQEVIRVNREFKCMAGCCWCASCAMVVTIEAPXGN HIGTVRQACLAPKYQIMDAVFMIEGPICMCQGPCCTQDMDFKVFSHEVGKISKQWSGFVR EYFTAADNFGITFPMDLDVKMKQHDWSS-FLIDFMY------XXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-- --------------------KRMKLTLMEEVLLMGLKDREGYTSFWNDCISSGLRGCILI ELALRGRIELEKTGMRRRSLLNRKIVVKSGSLTGDVLLDEALKHIKATEPGETVQTWIEY LSGETWNPMKLGYQLRNVRERLAKSLVEKGVCTTDE------------------------ ------------------------------------------------------------ -----------------------AVIVHDSQAQECEVCVNMLTKFSETLSKLRLFCENSA KRSREKTSVFCFXIGAREDSATSTIGDVSKPLSFYMPPEKICDKTKLKTSQICELKYEKQ IDLVNANFKKXKVKELKKILAIWNEDCKGCTEKSEFIARVEXLMPTYAPEAA-------- -----------------------------------------------------EEMTRFR LEXRVMFKGKCLEEWNFDLXFVIPGSTNTWQSVIEAAPESQMMPASVLSGNVVIETYFYD DKLLVSTSKVRIYYVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------- ---EMAFTFATPSECKVKQVDVPALSGDFGILAQHVPTLAVLKPGVLSVHEEDSTTNKYF VSSGSVTVNSDSSVQILAEEAQPLDRLDAAAIRDGLAKAQQEMSSEKAKAEAQIAVECYE AMQKAL-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------- -LGQLNAVVNCAGTAVAFQTYNFSKHRPHELESFTNVQMVNVVGTFNVIRLSCKLLSANE PGPDGNKGVIVNTASVAAFDGQRGQAAYSASKGAIVGMTLPIARDLAQAGIRVNTIAPGL FDTPLMASLPEKVRKFLADTVPFPKRLGYPDEFAHLVQSVIENPMMNGEVIRLDGA---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------DRYAPTA RDLASRDIVSRAETIEIREGRGLGXNKDHMYLQLSHLPPEQLKANLPGISETAMIFAGVD VTRDPIPVLPTVHYNMGGIPTNYKGQVLDYEGGDRVVPGLYAAGEAACVSVHGANRLGAN SLLDIVVFGRACALEIAAEHKPGEKIKDLSPDAGEMSIANLDKMRYADGDTPTSALRLRL QKAMQDNAAVFRDGPTLQEGVEKVQQCYDAMDLKVSDHGLIWNSDLVETLELQNLMLVSS QTVVSAENRKESRGA---------------------------------------DPVTGK VSLSYRPVIDSTLDD-DVEMVPPKLRVYMTAMTQEEIVSSTKTVIQGLEALKNEHNQILT SIKASLSAIKTTTHLLIDEKAGLMRKSLENIDLGLGEAQVMMSLAQHLQHVEAEKQSXES SSQRLCQXNGWLRDELATTQTKL------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------KVDKNRDPEAEAKAVAWMTEVLGPPAGTYED SLKNGAYLCELINAI------KKIHQKGQAFTVMQNIEAFQKALVAYGVPAEDLFQTVDL WEKGTYPQPKTPAGSAPSEASAKNWDGPMLGPKMATKNEREFTEEQIRAGRLQAGYNKGA TQNMG------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------------MA TQYRFGVEPITCHAWNKEQTQLALPNNDEVHIYGLQWVKQHTLSEHTQRVTGIDWAPKSN RIVTCGVDRNAYVWPVLVILRINRAATCVKWSPEEN------------------------ ------------------------------------------------------------ ----------------------------------------KTSYYLSTSCLWVTENSLVV GGYDNLPLLFNCSQGAINFVNKLDIGSMSAMKRFQQMDTRGRKVVTLHQNAIRQLTLHSG SKSSCAKFASGGNDGQILVWD--------------------------------------- ------------------------------------------------------------ --------------------------------------CCLYFIAPXGHGLKPLDIEFMK RLHDKVNIIPLIAKADTLTPEECRDFKKTILNEIEKNQIRIYEFEDEEENGMXKKLKERV PFAVVGSNRVMEVNGKKVRGRQYPWGVVEVDNLQHNDFLALRDMLIRTHMQDLRDVTNNV HYENYRYKKLANVSSDPLTQMEEERKEHRQKMKKMEAEMEQVFEIKVKEKMQKLKDSETD LQRRAEQMKKSLEQQKAELEQKRIAFLEEKRLWESQ--MSRRYDSRTTIFSPEGRLYQVE YAMEAIGHAGTCLGILASDGILLAAERRTTNKLLDEVSYSEKXYKLHDDMATSVAGITSD ANVLINELRLIAQRYLLTYQEPMPCEQLVSTLCDIKQAYTQFGGXRPFGVSLLYMGWDKH YGYQLYQSDPSGNYSGWKATCIGNNSAAAVSMLKQEFKEEGLGLSEAKRLAIRVLSKTLD MTKLTCEKVEIAVLSRVDDKTKITILANEEVTELIKEFEAKE------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------DDLGKNLMAVRNLVRKHELLEEDIAAHGERINDLTTQCDEFIDANVGD AEDMRSRKETMNVR---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------YAKIQDMAATRGAKL AESNSLQEFLR------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------QSQNCPANKPFDDKINALVDCLSDEAHVPGAYXCKREYRSPG WXGWHKVTRRCGT-------------------------------------XXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------ILKAHGKSAKETVLVNGYALNCTVGSQQMPKRIVNPKIACLDFSLQKTRLKLG IQILVEDPEKLEGIRQREADITKDRIQKILATGANVILTTGGIDDLCLKYFVEAGAMAVR RCKKVDLXRIAKCTGATFMMTMANMEGEESFEASMLGTCRRXFKERICDDELILIKGPKS RSAASIILRGANDFMVDEMERSMHDALCVVKRVLESKSVVPGGGCVEAALSIYLENLATS LSSREQLAIAEFSRALLVIPKQLAVNAAQDSTDLVSKLRAFHNTSQMKAEHKNLKWVGLD LVKGTVRDNKKAGVFEPAVSKIKS------------------------------------ ------------------------------------------------------------ ----------------------------------ADITYKTIENEVQIGYSSAPGEGAIY GLEDYERVFSPHIADWAVIALMTVPTLAFPYFLWLKSHKQYSG-KSKRSXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXX-------KGKKNNVGFIQLNRPKALNALCDALMKEL QTALSDFSKDEEVGCVVLTGSNKAFAAGADIKEMQPREFAEVYKGXFLGFWNSISLFKKP IIAAVNGYALGGGCEIAMMCDIIYAGEKAKFGQPEILLGTIPGGGGTQRLTQAVGKSKAM EMVLTGDQISAQEALQFGLVANVYPVEELVDKVIEKAKKIASMSQIATGMAKEAVNSSYE MTL------------------------------------- >Capitella_teleta MSERKAVIKNADMSEEMQQDAVDCATQALEKFNIEKDIAAYIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYMGQVAVLLFKSGVLQVLRQFQTSASRQDIDQAAKYIGAGAATI GAGGSGAGIGSVFGSLVIGFARNPSIKGQLFSYTILGFALSEAMGLFCLMMAFLILFAFM SQYKD-AKGPEPTIHRIRITLTSRNVKSLEKGCADLIRGAKDKNLKVKGPVRMPTKVLRI TTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADMDQVM QCVEPSKQFAKDSIRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNII VMATQISKKRKFVANGVFKAELNEFFTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVL GEKGRRIRELTSVVQKRFNFQEGTVELYAEKVATRGLCAIAQAESLRYKLIGGLAVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGNPTNDYVDKAVRHVLLRQ GVLGIQVKIMLPWDPTGKIGPKRPLPDHVSIVEPKDERAPEHPYSEHKVAKMSKRGRGGT SGGKFRISLGLPVGAVMNCADNTGGKNLYVIAVHGIRGRLNRLPAAGMGDMFVATVKKGK PELRKKVMPAVVIRQRKAIRRIDGVFLYFEDNAGVIVNNKGEMKGSAITGPVGKECADLW PRIASNASCIRKGKTERVSLGPQVAEGELVFGVAHIFASFNDTFVHVTDLSGKETIVRVT GGMKVKADRDEASPYAAMLAAQDVAERCKVIGVTALHIRLRATGGNRTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRKKGGRRGRRLMGKPRGLRTARKQKNHRREQRWHDKD YKKSHLGTRWKSNPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP RDGCLNYIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKEKKERPRAEGT ATIRTRKFLTNRLLNRRQMVVDVLHPGRATVPKTEIREKLGRMYKTTADVVFCFGFKTQF GGGKTTGFALIYDTLDYAKKLEPKFRLARXGGRKQRKERKNRQKKVRGVKKSKVGAMPRI PMVTSKTYATPRRPFEKERLDQELKIIGEFGLRNKREVWRVKYTLAKIRKAARELLTLDE KDPKRLFEGNALLRRLVRIGVLDEGKMKLDYVLGLRVDDFLERRLQTQVFKLGLAKSIHH ARVLIRQRHIR------------------------------------------------- --MGNMFERIFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIAEAREELMRMLAEDELRD AVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRHWYIQATCATSGDGLYEGLDWLSNQLK NPKMPLARDLLHPSLEDEKRRCKLKRLVQSPNSYFMDVKCPGCYKITTVFSHATTVVLCV GCSTVLCQPTGGKARLTEGCSFRKKQHMVRVNVLADALKSICNAEKRGKRQVLIRPCSKV IVRFLTVMMKQGYIGEFEIIDDHRSGKIVVNLTGRLNKCGVISPRFDVRMSDLEKWTTNL LPSRQFGFLVLTTSGGIMDHEEARRKHLGGKILGFFFMGRMHAPGKGISQSALPYRRTVP TWLKLSSDDVKEQIFKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKVLRILKSKGLAPE IPEDLYHLIKKAVSMRKHLERNRKDKDTKFRLILVESRIHRLARYYKTSKVLPPNWKYES ATASAMVAMTDVPEVKLFGKWTSEDLQVSDISLTDYIPIKEKYAKYLPHSAGRYQVKRFR KAQCPIVERLACSLMMHGRNNGKKIMAMRIVKHAFEIIHLLTSENPLQVLVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCHGAREAAFRNIKTIAECLADELINAAK GSSNSHAIKKKDELERVAKSNRMGEQMALRTTLIGHGDWVTQVATTPGFPDALVSASRDK TLILWKLSREGIYGQATKCLKGHEHFVSDVVLSSDGQFALSGSWDSTLRLWDLSTGQTTR RFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIDESHSDWVSCVRFSPNT QNPIIVSAGWDKIVKVWNLTNCKLKTNHYGHSGYLNCVTVSPDGSLCASGGKDGQAMLWD LNEGKHLYTLDGGETINALTFSPNRYWLCAATGPYIKIWDLENKLVVDELRQEVISS-GK APECTSLAWSEDGQTLFAGYTDKVIRVWQVSMSQRMKEYKLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKVVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKLARHWNCAFLETSAKSK INVNEIFYDLVRQINRKNPDT---------EHINLKVTGQDGSVVHFKIKKNTPLRKLMT TYCERTGVKMGSMRFRFDGNPINEHDTPSTLDMEDGDAIDVFQQQTGG--AMPLNPKPFL NGLTGKPVMVKLKWGMEYKGYLVSVDGYMNLQLANTEEFIDGTLSGNLGEVFIRCNNVLY VRGVEEEDEEGEMKD--DAEGDDTPQVAPTGGPMDINTAIQEVLKVSLIHDGLARGLHEC AKALDKREAHLCILANNCDEPMYVKLVEALCGEHGINLIKVDDNKKLGEWAGLCKIDKEG KARKVVGCSCVVVKDYGKESQALDVLNEYFKGRKMAAIRKKLVIVGDGACGKTCLLIVFS KDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSI DSPDSLDNIPEKWTPEVKHFCPNVPIILVGNKRDLRNDDNTKRELMKMKQEPVRPEEGKA MADKINAFAYLECSAKTKDGVREVFETATRAALETKKKKKNIMDDFQSAEESAFVVDEVS NIIKESIEGAIGGNAYQHTKVNQWTSNVVEQCLNQLTKLGKPFKYIVTCVIMQKNGAGLH TASSCFWDNATDGSCTVRWENKTMYCIISVFGLAIMYSASVKIVKPRDEKPDELESQVSQ ALLELEMNSDLKAQLRELHITGAKEVDVADKKAIMIFVPVPQLRAYQKIQARLVRELEKK FSGKYVVFIAQRRILAKPTRKVRTKSKQKRPRSRTLTTVHENILDDLVFPAEIVGKRIRI KLDGSRLIKVHLDKTQQTNIEHKLDTFTAVYKKLTGKSVTFEFPEFVLGRGGFRGGFG-- GRGRGRGRGRGKEGDKEWVPVTKLGRLVKDMKIKTLEEIYLFSLPIKEFEIIDYFLGATL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDFNGHVGLGVKCSKEVATAIRGAIILAKLSV IPVRRGYWGNKLGKPHTVPCKVTGKCGSVVVRLIPAPRGTGIVSAPVPKKLLTMAGIDDC YTSASGQTATLGNFAKATYAAIAKTYSYLTPDLWRETVFTKSPYQEYTDYLMKMSGGLDV LALKEEDTIKMLACATHLGAANSDFQMEQYIYKRKSDGIRIINLRRTWEKILLAARAIAA IENPAEVCVISARPYGQRAVLKFAHYTGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDP RTDHQPITEASYVNIPVIALCNTDSPLKYVDIAIPCNNKSINSIGLMWWMLSREVMRLRG TISREVPWDVMVDLFLYRDPEEAEKESAEADWATEGLVPAVPVATDDWAATDTGDWATAQ PASDWGGMKINKLVTSSRRKTRNRYFNAPSHLRRKIMSAPLSKELKQKYNVRSIPIRKDD EVQVVRGHYKGQQVGKIVQVYRKKYVVHIERIQREKANGASVHVGIHPSKVVVVKLKMDK DRKSILERKARGRQTGKHTEETIVSASATSVGSTVRQRKAPASGASAAGMWRFYTEDSPG IKVGPVPVLVMSLLFIASVFMLHIWGKYTR-KKEGKKKTVTSEVVTREHTINLHKRIHGV GFKKRAPRALKEIRKFAEKHMGTPDVRVDTRLNKFIWQHGISNVPFRVRVRMARKRNEDE DSTHKLYTLVSYVPVTTFKGTQTVNVES---AEFLVNGRYRLVRKIGSGSFGDIYLGINV SNGEELAVKLESHKARHPQLLYESKLYKILQGGVGIPHTRWYGEKDYNVLVMDLLGPSLE DLFNFCSRRFTMKTVLMLADQMIGRIEFVHNKNFIHRDIKPDNFLMGIGRHCNKVFLIDY GLAKKYRDNRSRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRGS LPWQGLKAATKKQKYEKISEKKMSTPMEVLCKGYPAEFAMYLNYCRGLRFDEAPDYMYLR QLFRIMFRTLNHQYDYVFDWTILKQKAA--MNAEKLKQRIGGKGSARRKKKVVHRTATTD DKKLQTSLKKLSVNNIPGIEEVNMIKEDGQVIHFNNPKVQASLAANTFAITGHAETKQIT EMLPGILNQLGAESLSNLKKLATTTDNIDEEEDELPELVENFDEASKAEMTRYSQDAENA TKSAKAKGSHLRVHFKNTRETANTIKRMHLRRAVAFLKNVTQMKECVPFRRYNGGVGRCA QAKNWNTTQGRWPKKSAEFLLQLLKNAESNAEYKGLDTDHLVIEHVQVNRAPKMRRRTYR AHGRINPYMSSPCHIEIILAEKEQAIAKPTKKKVSQKKLKKQKAMMREKKAGPKPELTED QKQEIREAFDLFDADGSGTIDAKELKVAIRALGFEPKKEEIRKMIADIDKEGTGTIDFND FLSMMTQKMSEKDSKEEIQKAFRLFDDDETGKISFRNLKRVARELGENLTDEELQEADRD GDGEINEQEFLRIMKKTSLYMGISQDKWHKRRKTGGHMPIMRKKRKFELGRPAANTKLGS YRVHKVRIRGGGYKMRALRLETGNYSWGSEAQTRKTRLLDVVYNASNNELVRTKTLVKNC IVQIDATPFRQWYEAHYAVPLGRRKGMKLTEAEEAVLNKRSKKTQKKYDERKKTAKIDTA LEEQFITGRLYACVTSRPGIHGRCDGYILEGKELEFYARKIKAKKGKMSLVIPEKFQHIL RVMNTNIDGQRKIAYALTAIKGIGRRYSHVVCKKADVDLTKRAGELSEEEVEKVITIMSN PRQYKIPDWFLNRQKDVKDGKYSQVMANILDSKIRDDLERLKKIRAHRGLRHYWGLRVRG QHTKTTGRRGRTVGVSKKKGSGSDSDSDE-------MAQAAGLGEELPSKAKQTRSEKKA RKAMSKLGLKQVAGVTRVTIRKSKNILFVINRPDVYKSPASDTYIVFGEAKIEDLSQQAQ MAAAEKFKSEEEVDETGIEAKDIELVMSQAYVSRGKAVKALKNNSNDIVNAIMMGRVRTK TIKKASKVMIEKYYPRLTHDFHTNKRIVEEIAIVPSKKLRNKIAGFITHLMKRIQKGSVR GISIKLQEEERERRDNFVPETSAIDEVDIDTKEMLKMLDMANLPGLQVTQPIVSGMKWEY KEEHPFEKRRAEGEKIRKKYPDRVPVIVEKAPKARVGDLDKKKYLVPSDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGALYQEHHEEDFFLYIAYSDESVYGMRDLRIMKL CLNICVGESGDRLTRAAKVLEQLTGQQPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAE EILEKGLKVREYELRRHNFSATGNFGFGIQEHIDLGIKYDPSIGIYGMDFYVVLGRSGFN INHRRKKTSSIGAKHRVNKEESMKWFQQKYDGVILPGKMGFKFLEFVKPFCAVLPEIQKP ERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVIMASNRGTLMELGIS PIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMVITVGQAIVYVMTGMYGDPAD IGTGVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVN TGRGTEFEGAVIALFHLLATRQDKVRGLREAFYRQNLPNLMNLLATIFVFAIVIYFQGFR VDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAAKFSGNFIVNLLG TWADVGGGGPARSYPIGGLCYYLSPPETLWHVTEDPIHAVLYIVFMLGSCAFFSKTWIEV SGSSAKDVAKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIG SGTGILLAVTIIYQYFEIFVKEQSEMGGMSTLLFQVERAFQKQKGIFLNKKKVVVPRYVK NVGLGFKTPREAVEGTYIDKKCPFTGNVSIRGRILSGIVMKTKMQRTIVVRRDYLHYVRK YNRFEKRHKNISAHCSPCFRDVAIGDIVTMGECRPLSKTVCFNVVKVNKGASSKKGFSKF MVNVPKARKTYCKGRKCHKHTLHKVTQYKKGKDSICAQGKRRYDRKQSGYGGQTKPIFHK KAKTTKKIVLKMECTECKFRKQLPIKRCKHFELGGDRKKKGQMIQFMGRVIRCQRKGAGS VFKAHSKHRKGPAKLRTLDFAERRGYIKGVVKDIIHDPGRGAPLAKVAFRDPYRYKQRME TFIAAEGMYTGQFLYAGKRATLTVGNILPVGQMPEGTIVCAVEEKSGDRGKLAKTSGNYA TVISHNPDAKKTRVKLPSGAKKQLSSSNRAMIGIVAGGGRIDKPMLKAGRAYYKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGMASTVRRDTPAGRKVGLIAARRTGRLRGSKQFTS KAKRTKKVGICGKYGTRYGASLRKDIKKMEISQHSKYTCSFCGKENMKRKAVGIWKCKSC KKTVAGGAYVYSTNAGATVRSTVRRLRENKDMGRRPARCYRYCKNKPYPKSRFCRGVPDP KIRIFDLGRKKARSDDFPLCVHLVSDEWEQISSEALEAGRICANKYLTKHCGKDAFHLRV RLHPFHVVRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQVIMSVRARDTHTAKVI EALRRAKFKYPGRQKIYISSKWGFTKWERVDYEKMREDGVLIPDGVGVQYKPNKGPLQAW KNRQQVTKILGRTGSQGQCTQVRVEFLDESSRSIIRNVKGPVREGDILTLLESEREARRL RMTKGTSSFGKRHNKTHTLCRRCGGRCFHIQKKKCSRCAYPEAKMRKYNWSEKAKRRRTQ GVGRMRYLKKVFRRFRNGFREGTVAKKANP-MDDRAAAKDLDQWVEQLMECKQLSENQVK SLCEKAKEILAKESNVQEVKCPVTVSGDVHGQFHDLMELFRIGGRSPDTNYLFMGDYVDR GYYSVETVTLLVALKVRFKDRITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHTNNLTLVTRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRC GNQAAIMELDDALKYSFLQFDPAPRRGEPHVTRRTPDYFLMGAYKYMQELDRKKQTDAMR FLLRVRTWHLRQLNSIHRAPRPTRPEKARRLGYRAKQGYVIYRVRIRRGGRRRKAPKGQV YGKPVNHGITQLKNQRSIQAVAEERVGRKCQQLRVINSYWVAQDATYKFFEVITVDPFHK AIRRDPKIQWICESNAKHREMRGLTSANKKSRGLGKGHRYTKTTGGSRRGNWKRRNTLQL RRKRGIALGRLSEERKAWRKDHPFGFVARPTKATDGTLNLMNWECAIPGKKGTAWEGGLY KLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSLLDEEKDWRPAVTIKMILLGIQE LLNEPNIKDPAQAEAYTIYCQNRVEYDKRVKEQSLRFPDPSLGRSSKMLQHINFRMRCTL LDGRTFIGTFLAFDKHMNLILGDCDEFRRVKPK-GKGKEEKRVLGLVLLRGENLVSMTVE GPPPAEEGIARVPIPGATGGPGMGRAAGRGVPMGGGLAGPVRGVGGPAQSHMQPGPGRGS FAPPPNIATFKLVLVGDGGVGKTTFVKRHLTGEFEKKYIATLGVEVHPLVFHTNRGAIRF NVWDTAGQEKFGGLRDGYYIQGNCAIIMFDVTARITYKNVPNWHRDLVRVCETIPIVLCG NKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLTGEPNLEFVAMPA LAPPEVQMDAAMAAKYEEELKVAQTTALPEEEDDLKEGIKQYYVSKIEELQLVVSGKTQN LRRLEAQRNELNAKVRLLREELQLLQEQGSYVGEVVKPMDKKKVLVKVHPEGKFVVDLDK NIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYDMVGGLDKQIKEI KEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ KFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRLESGSGGDSEVQRTMLELLNQLD GFEPKQNIKVIMATNRIDILDSALLRPGRIDRKIEFPAPNEEARLDILKIHSRKMNLTRG INLRKIAEMMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFELAVAKVMQKDSEKNMSI KKLWKLGFAENFALSGAAAVISKTAAAPIERVKLLVQNQDEMIKAGRLDKPYSGVVDCTM RTLKTEGVLPFWRGNLANCLRYFPTQALNFAFKDKIKIMFKMHKTDSYGVKFSKNIASGG AAGAMSLCFVYSLDYARTRLANDAKGGKKRQFNGLVDVYKKTLKSDGFVGLYRGFVISCV GIVVYRGCYFGFYDTLKPIVLGEDAGVMMSFALGYVVTITSGLISYPIDTIRRRMMMTSG EAVKYKGSIDCGMQVIKGEGFMSLMKGAGANILRGVAGAGVLAGFDKFKEVYIAFRLMAD MSDLDRQIEQLRRCEVIQESEVKALCAKAREILIEEGNVQRVDSPVTVCGDIHGQFYDLK ELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQV YGFYDECLRKYGSITVWRYCAEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRSIDRK QEVPHDGPMCDLLWSDPEDTQGWGVSPRGAGYLFGSDVVQQFNSANDIDLICRAHQLVME GYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQREFTIFEAAPQEQRGKPQADYFL VRLPPEVNRILYVKNLPYRITAEEMYDIFGKYGAIRQIRVSNSQDTKGTAFVVYEDIFDA KNACDHLSGFNVCNRYLVVLYYQPNKVYKKVDQDKKQEELDRMKAKYGLSTPK--MSIGV PIKVLHEAEGHIVTCETTSGEVYRGKLVEAEDNMNCQMANITVTYRDGRVAQLENVFIRG SKIRFLILPDMLKNAPMFKRVTAGRGKSAILRAAARARGRGIPGRGGG-MQNEAGEYVDM YIPRKCSTSNRIIGAKDHASIQLNLAEVDETTGRMTGQYKTYAICGEIRRMGESDDSICR LARRDGVVAKMVRGPRMHLKRLAAPKHWMLDKLGGVFAPRPSTGPHKLRECLPLVIFLRN RLKYALTYTEVMKILNQRLIKVDNKVRTDKTYPAGFMDVISIERTNENFRLIYDVKGRFA VHRITPEEAKYKLCRVRALKTGPKGVPFLTTHDARTIRYPDPLIKPNDTVQVMGTKDDEY DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTA GQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADNNIVIMLVGNKSDL RHLRAVPTDEAKAFAEKNNLSFIETSALDSTNVETAFQNILTEIYKIVSQKQIRDSPDDN NVQTITVAPTDNSADKKQKCC-MTARYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVR GKDIVVLGVEKKAVAKLQEDRTVKKIALLDEHVALAFAGLTADARILIQRARVECQSHKL TVEDPVTLEYITRHLAQLKQKYTQSNGRRPFGLSTLIIGFDGCPHLYQTDPSGTYHEWKA NAIGRSAKTVREFLEKNYSEDLVSDREAIKLCLKALLEVVQSGSRNMEVAVMARGQRLKT LEPEEVEVYIQEIEKEKEEEAEKKKQKGAGGGGDKKDGKDKKKKYEPPIPTRVGKRKKKM KGPDAANKLPQVTPHTRCRLKLLKMERIKDYLLMEEEFIRNQERLKPQEEKEEEERSKVD DLRGTPMSVGNLEEIIDDNHAIVSTSVGSEHYVSVLSFVDKDQLEPGCSVLLNHKVHAVV GVLGDDTDPMVTVMKLEKAPQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIKPPK GVILHGAPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPS IVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSKGDVKVIMATNRIESLDPA LIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTLANDVDLEDYIMAKDDLSGADIKAICT EGGLLALRERRMKVTNEDFKKAKENVLYRKNEGTPEGLYL-RKRYSPFQNSSNVDYALAR ADDLINWARKTSLWPLTFGLACCAVEMMHFAAPRYDMDRFGVVFRASPRQADCILVAGTV TNKMAPALRKVYDQMPHPRWVVSMGSCANGGGYYHYSYSVVRGCDRIIPVDIYVPGCPPT AEALLYSVLQLQKKIKRMKSTQIWYRKTDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYA NNSNYKNDTMIRKEAYVHKSVMEELKRIIQDSEVMQEDDQVWPPADRVGRQELEIVIGDE HISFTTSKIGSLVDVNQSKDPEGLRTFYYLVQDLKCMVFSLIGLHFKIKPIMVSQKKTKK AVESINSRLALVMKSGKYVLGYNQTLKSLRQGKAKLVIIANNTPPLRKSEIEYYAMLAKT GVHHYNGTNIDLGTACGKYYRVTTLSITDPGDSDIIRSMP--MTEYKLVVVGAGGVGKSA LTIQLIQNHFVEEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGF LCVFAINNSKSFEDINQYREQIKRVKDADEVPMVLVGNKVDLPSRTVDTKMGKMLADSYS IAYVETSAKTRQGVDDAFYTLVREIRKYMGDRYNIHSQLEHLQSKYIGTGHADTTKWEWL TNQHRDSFASYLGHFDMINNFAIVENETKARVRFNLMEKMMQPCGAPPEKPEDMKIELCN YSGYKIYPGHGKKVIKQDGRFFHFLNAKCERSFNMKRNPREVPWTVLYRRKHKKGQQEEV AKKRTRRTHKFQRAIAGASLTDIMAKRNQKPEVRKAQREQAIRAAKEKQKAKNAPKARVG GKRMKLNISYPATGCQKLIEVDDERKLRHFYEKRISAEVNADHLGDEWKGYVLRISGGND KQGFPMKQGVLTVGRVRLLLSAGHSCYRPRRSGERKRKSVRGCIVDANLSVLSLVIVKKG EQEIPGLTDSSVPRRLGPKRASKIRKLFNLAKDDDVRQYVVRRPLPPKSKAPKIQRLVTP LVLQRKRHRMAIKRQRSTRKREEAAEYAKLLAQRMKEAKDRKMERRKSSHSKSKVKAKEL RGKKRDELEKQLTDLKVELSQLRVAKVTGGAASKLSKIRIVRKSIARVMTVINQTQKENL RKFYMPKDLRPKKTRAMRRALTPHERSLKTRKQARKDSLYPLRKYALKADKKGPKVTDKV FFDIEIDGKSEGRIVIGLFGKTVPKTAKNFKTLAEGTETYTGSKFHRVIPNFMIQGGDFT RGDGTGGKSIYFEDENFKLKHYGSGWLSMANAGKDTNGSQFFITTKKTEWLDGRHVVFGK VLEGMSVVRKIEATKTGNDRPEKDVVIAKSGSLPVDAPFPVDKLPSEEKKKKILLKYTID CTHPVEDGIMDVASFEKYLHERIKINGRVNNLKSKLTVTCEIAFSKRYLKYLTKRYLKKN NLRDWLRVVANTKESYELRYFQINNEEEDEEADDKEDKGGEEEPRYGGCEGPDAMYVKLI SSDGHEFIVKREHALTSGTIKAMLSGPGQFSENETNEIIFREIPSHVLQKVCMYFTYKVR YTNSSTEIPEFPIAPEIALELLMAANFLDCSKKISLEELSKHTSPKDLWMSIHDDVYDIT KFLEEHPGGEEVLLECGGKYGTAPFEDVGHSMDARELMKQYKVGELEENDKSSWVSWLVP IGIACATAVVYRYVMSYMLQHLHNGWQVDQAILSEEDRVVIIRFGHDWDPTCMVMDETLY SVAEKVKNFAVCYLVDITEVPDFNKMYELYDPCTCMFFYRNKHIMIDLGTGNNNKINWSM EDEQEFIDIVETVFRGARKGRGLVVSPKDYSTKYRYKKLQRQLEFLEVQEEYIKDEQKNL KKEYLHAQEEVKRIQSVPLVIGQFLEAVDQNNGIVGSTTGSNYYVRILSTIDRELLKPSA SVALHKHSNALVDVLPPEADSSITMLSADEKPDICYADIGGMDIQKQEVREAVELPLTHF DLYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVR DVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTVNVKVI MATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITGKMNLSDDVDLEDFIARPD RISGADINAICQEAGMQAVRENRYVVLPKDFEKGYKNNIKKDETEHEFYKSHDPLSMTTI RDRVLLVLKLYDKVDPEKLTLESHFMNDLGLDSLDQVEVVMAMEDEFGFEIPDRDAEKLM RPADIVQYIADKEDVGRRVQPLTDDLKNVEFETSEEVDVTPTFDAMGLREDLLRGIYAYG FEKPSAIQQRAVRPIVKGRDVIAQAQSGTGKTATFSISILQGLDTQVRETQALILSPTRE LATQIQKVILALGDYMSVQCHSCIGGTKVGEDIRKLDYGQHVVSGTPGRVFDMIRRRSLR TRAIKMLILDEADEMLNKGFKEQIYDVYRYLPPATQVLLISATLPHEILEITSKFMTDPI RILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKM REANFTVSSMHGDMPQPEREAIMKEFRSGSSRVLITTDVWARGLDVQQVSLVINYDLPNN RELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLIAPMRRP FDPAAHDLDPNFRLTRFADLKGGCKVPQEVLLKLLEGLNTAHESEQSHFQYVAQMPHIGI GMDSCVTPLRHGGLSLVQTTDFFYPLVDDPYMMGKIACANVISDLYAMGVTECDNMLMLL AISQKMTDRERDVVIPLMIRGFKDCAEEAGTSVNGGQTVLNPWVTVGGVATTVCQSNEFI MPDNAVVGDVLVLTKPLGTQVAVNAYQWLEQPDRWNRIKLVVSEDDVRKAYQRAMFSMAR LNRMASRLMHKYNAHGATDVTGFGLLGHANNLARIQKNEVGFVIHNLPVIAKMAAVSKAC GNMFGLLQGHSAETSGGLLVALPREQAAAFCKDIEKQEGYQSWIIGIVEKGTRTARIIDK PRVIEVPAKEKE----LMKASDAYFINIDANAEECFFDKVTSGTKMSLMFEVAEGGFLDI DVKIVGPDGKNIYYGERESNGKYTFAAHMDGVYKYCFSNQMSTMTPKIVMFSMDIGDKPK AHHNKLEEMINELSTSLTGVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLIAMT LGQVYYLKRFFEVRRVVMAATLKPYLTAVRHTLTAAMCLENFSSQVVERHNKPEVEVMSS KELLLSPVVISRNEKEKVLIEGSINSLRISIGVKQADEIEKILCHKFMRFMMMRAENFIV LRRKPVKGYDISFLITNFHTETMFKHKLVDFIIHFMEEIDKEISEMKLAVNSRARISAEE FLKRFSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLV TMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTVPNTFKTLDSWRDEFLIQASPRDPEN FPFVVIGNKIDLENRAVSTRRAQQWCQTKGDIPYFETSAKEAINVEQAFQTVAKNALAQE TEVELYNEFPDQIKLSNDQNKDGCGCTAPFDPRFPNANQTKSCWLHYADYHKCLAIEDYE PCNYFKKVYKALCDITTIDKFEEMRENGTFPIR-MPDHLGKDQRSTKDDKDEDKPIQSLD EGDIALLKTYGAGMYSSSIKQTEDDISSILKRVNELSGIKESDTGLAPPALWDLAADKQT LQSEQPLQVARCTKIINADTDDPKYIINVKQFAKFVVELSDQVAPTDIEEGMRVGVDRNK YQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGI EPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMART KKACIVFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDT LDPALMRPGRLDRKVEFSLPDLEGRSHIFKIHARSMSVEKDIRYELLARLCPNSTGAEIR SVCTEAGMFAIRARRKMATEKDFLEAVNKVIKAYAKFSATPRYMTYNMGKEKTHINIVVI GHVDSGKSTTTGHLIYKCGGIDERTIAKFEKEAQEMGKGSFKYAWVLDKLKAERERGITI DIALWKFETDKYFVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGMGEFEAGISKNGQT REHALLAFTLGVKQLIIGVNKMDNTEPPYSEARFKEISKEVEAYIKKIGYNPKAVAFVPI SGWHGDNMLKMPWFKGWNVASGKTLYEALDSILPPERPTDKALRLPLQDVYKIGGIGTVP VGRVETGIIKPGMVVTFAPCMVTTEVKSVEMHHTSLPEALPGDNVGFNVKNVSVKEIRRG YVAGDSKNDPPKETDEFRAQVIVLNHPGQISNGYAPVLDCHTAHIACKFQELIEKIDRRS GKTMEDKPQHVKSGDAAIVEMKPGKPMCVEAFADYAPLGRFAVRDMRQTVAVGVIKSVKK KEGGSGKVTKAAVKAELEQLRVETEQLKNQIREARKAAADTTLTQAAAHVEPVGRIQMRT RRTLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDSFTTNKVHAIPLRSSWVMTCAYAP SGSYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIVTSSGDMTCA LWDIETGQQTTSFAGHTGDVMSLSLAPDMRSFVSGACDASAKLWDIRDGMCKQTFSGHES DINAITFFPNGFAFATGSDDATCRLFDLRADQEIGMYSHDNIICGITSVAFSKSGRLLLG GYDDFNCNVWDTLKQDRAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKIWN------- --------GVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES FRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARR DVKKEEGEAFAREHGLVFMETSAKTAANVEEAFINTAKEIYQKIQDGVFDINNEANGIKI GPQHSTSSQSGGGGATPGGGMTRGRTELGDVTVHNIKQLKRLNQVIFPVTYNDKFYKDLL EVCEHAKLAYFNDIVVGGVCCREFRTYGIRKLYIMTLGCLAPYRRLGIGTVMLEHVLKLC EQDGQYASIFLHVQVNNESAIGFYEKFGFKIVDRKENYYKRIEPADAFVLEKDLTTMPKQ IMEIKDFLLTARRKDAKSVKIKKNVKFKVRCSRYLYTLVISDLEKAEKLKQSLPPGLAVK ELKMSKLSRDTVNEAAASVLKKKRKFTETVELQISLKNYDPQKDKRFAGTVKLKHIPRPR MKVCILGDQQHCDEAKVNNLSNMDVDSLKKLNKNKKLVKKLAKKYSAFLASDSLIKQIPR ILGPGLNKAGKFPTPLSHGESMSAKVEEVKATIKFQMKKVLCLSVAVGHVQMSADELTSN IILSVNFLVSLLKKNWQNVRALYIKSTMGPAIRIFMAEADKLNIDSIISRLLEVRGSRPG KNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKETTGWGENDRGVSFTFGVEIVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLQAGRPVTPPRGSKHVK GKMMFKNTFQSGFLSILYSVGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEISGTNVSTT YVTCPADPKRSLGIKLPFLVMIIKNLKKYFTFEVLVLDDKNVRRRFRASNYQSTTRVKPF ICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYVETLRVQIHANCRIRRVYFSDRLYSEDEL PAEFKLYLPVQ--MTDPTFHNLKDPFSEEEKVHIRIQQRNGRKTLTTVQGIKPEFDLKKI VKVAKKEFACNGTVVEHPEYGEVIQLQGDQRQLISNFLKEVGLTESIKVHGFSAIFNFQS LLTVVLLLICTCAYIRSIAPRLLDKNKEGLLGVFWKCARIGERKSPYVAVCCIAMAFSIL FWSSGRLAAALARQLPRAATQRNTLGAGYVAARNFTTSAEVSTILEERILGSTMTDLEEF GRVLTIGDGIARVYGLKNIQAEEMVEFSSGLKGMALNLEPDNVGIVVFGNDKLIKEGDIV KRTGAIVDVPIGEGLLGRVVDALGNPIDGKGPIENATRARVGVKAPGIIPRISVKEPMQT GIKAVDSLVPIGRGQRELIIGDRQTGKTAIAIDTIINQKRFNDGTDEKKKLYCIYVAIGQ KRSTVAQIVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCAMGEFFRDNGKHALIMY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSDAFGGGSLTALPVIE TQAGDVSAYIPTNVISITDGQIFLETELFFKGIRPAINVGLSVSRVGSAAQMKAMKQVAG SMKLELAQYREVAAFAQFGSDLDAATQQLLNRGVRLTELLKQGQYVPMAVEEQVAVIFAG VRGHLDKMDPAKITDFEEKFLSHVRLTQQDLLSTIRKEGMISESSEATMKALVTEFLANY MEALYAAPFAVLECPNLKLKKPSWVKPPSAMFIFSLVLLSYFLVTGGIIYDVIVEPPSIG STTDERGNSKPVAFMPYRVNGQYIMEGLASSFLFTVGGLGFIMLDQTNKPTTPRINRILL ISFSFICILLSFFMCRVFMRMKLPMPKVKRSRKPPPDGWELIEPTLDELDQKMREAETES HEGKRIVEALWPIFRIHHQRSRYIFDLFYKRKAISRELYDYCLKENIADKNLIAKWKKPG YENLCCLRCIQTRDTNFATNCVCRVPKTKLEEGKIVECVNCGCRGCSGEYAQVTKMLGNG RLEALCFDGTKRLCHIRGKLRKKVWINQSDIILIGLRDYQDAKADVILKYTPDEARNLKS YGELPESAKINDEQDDNITFDEIDDVLVRFLMKLSHETVTIELKNGTMVHGTITGVDVSM NTHLKSVKMTIKNRDPIQLDTLSIRGNNIRYYLLPDSLPLDTLLIDDTPKSKGRG----K PKSEMTPEELAQREQEEFNTGPLSVLTQSVKNNTQVLINCRNNKKLLGRVKAFDRHCNMV LENVKEMWTEVPKTGKGKKKSKPVNKDRFISKMFLRGDSVILVLRNPLPILIDGRGHLMG RLATLVAKSLLQGQRVVIVRCEGINISGTFYRNKLKYLAYLRKRMNTNPSRGPFHFRAPS KIFYRVVRGMLPHKQHRGREALGRLKVFEGIPPPYDKQKRVVVPSALKVLRLKSRRPFCS IGRLSSEVGWKYQGVVATLEARRKVKAAQFHKVKVADNKLREKAKKIAPSQKIIESYG-- GNIEKGKKAFIQRCAQCHTVEAGGKHKTGPNLHGLIGRKTGQAPGFTYTESNKNKGITWD KDTLFTYLENPKKYIPGTKMIFAGIKKKGERQDLIAYLYSSTQIYVERTLAIIKPDAVAE EIEDIILNSGFTILQKRRVHLTPEQASEFYVEHYGKLFFPSLVAYMSSGPVIALALAREN AISHWRMLVGPTSVTEAKETHPDSLRALYGTDQQRNGLHGSDSYTSAEWEVRFFFPDSIV EPIAVGQAARDYLARSVNPTLLKGLTQLCKKKPDDPVVWLADWLLENNPNKPRVKMFEAR LAQGTLLKKVLEAIKDLLNEATWDCNENGMSLQAMDSSHVSLVSLTLNAEGFEPYRCDRN CSLGINLASMSKIFKCASNEDSITIKAGDEGDTITYVFESPNGDKVSDYEMKLMDIETDH LGIPDTTYSCVVKLPAAEFQRICRDLSQIGESVTICCTKDGVRFSASGDLGSGNIKLAQN ANVDKEDEAVTIEMQEACTLTFALRYLNFFCKATPLSPQVTLSMSNEVPLVVEYKIGEMG HVRYYLAPKIEDEADS-----LHTTQNTPKGKIIAVIGAVVDVQFDEDLPPILNALEVKN RAPKLILEVAQHLGENTVRTIAMDGTEGLIRGQECVDIGTPIRIPVGPETLGRIINVIGE PIDERGPVNSKHFAAIHAEAPEFVEMSVEQEILETGIKVVDLLAPYAKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVISLKDDTSKVSLVYG QMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIA ELGIYPAVDPLDSNSRILDPNVVGNEHYDIARGVQKILQDYKSLQDIIAILGMDELSEDD KLTVSRARKMQRFLSQPFQVAEVFTGSEGKLVPLKETIKGFQMILNGEMDHLPEVAFYMV GGIEEVTIKADKLAAERMLMPKKNRVAIYEHLFKEGVIVAKKDFRAPKHPELEVPNLHVI KALQSLKSRGLVKEQFAWRHYYWYLTNEGIQYLRDFLHLPPEIVPATLKRQPMGEDRDAY RKRAGADKKGDAGAGSNMGKTNSKLKPEVLEDLRANTEFSDDEIQEWYKGFLKDCPSGNL SVEEFKKIYGNFFPYGDASKFAEHVFRTFDTNGDGTIDFREFICALSVTSRGKLEQKLKW AFSMYDLDGNGYISRQEMLEIVTAIYKMVGTVMKMPEDESTPEKRTDKIFRQMDKNLDGK LSLEEFIEGAKSDPSIVRLLQCDPMSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNL TGLNEQVPHYRQALDMILDLEPDDDLEDNPGQSDLIEQAAEMLYGLIHARYIMTNRGIAQ MIEKWQQGEFGYCSRVYCENQPMLPIGLSDVPGDAMVKLYCPKCQDVYSPKSSRHHHTDG AYFGTGFPHMLFMVHPEYRPKRPANQFTPRLYGFKIHPLAYELQYQAAANFKSGYGNSKR MTNTKGYRRGTRDLFSRRFRKKGVIPLSTYMIQYKRGDIVDIKGFGAQQKGMPHKSYHGR TGTIYNVTKHALGVIVNKRVRGRIIPKRINVRVEHVKQSKCRQDFLNRVSANETAKKEAK EKINLRRIPVQPREGHFVKTKNNLPQVLEPIPYEFIAASRSHWKNISDKPAEDTWSDITD RAANIVFMKEILSGLGLILGQTLKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAICPAQAITIEAETRSDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEY STETHEELLYNKEKLLDNGDRWEPEIAANLQADHLYRMATQAKQAKADTKNNHENDKEQQ EAIEQIDEVQNEIDRLNESASEEILKVEQKYNKLRQPYFQKRSELISKIPNFWVTAFVNH PQVSALLNEEDEEALQYLTKVEVQEFDDIKSGYKINFHFGDNPYFENKSISKEFHLNSSK STAIDWKAGKDLTKKTKKRGLEEQDSFFGWFLDHGDAGADELGEVIKDDIWPNPLQYYLA SEIDEEGVDEEGLDDEE-KLTKQEELLLQDFSRNVSTKSSALFYGNAFIVSAIPMWLFWR IHQMDLQVVFVAMTLVCTYLVAFAYKNHKFLLKHQIAQKRGEAVSHEIMKKVEGDKKMSK QEKEERILWKKNEVADYEATTFSIFYNNALFLTFVIVASFYVLRSFNPTFNYVLSMASAG GLLALFSTGTK--QSKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQT VCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVRELQRQ ASPNIVIALAGNKADLRMVEYEEAQAYAEENSLLFMETSAKTAMNVNDIFLAIAKKLPKN EQAVDLSQENMAEYLASIFGTEKDKVNCSFYFKIGACRHGERCSRLHNKPTFSQTMLLQN LYINPQNTAQIIMSDEQVQQHYDDFFEEVFVELEDKYGEIEEMNVCDNLGDHLVGNVYIK FRSEESAEKGVEELNNRWFNGRPIHSELSPVTDFREACCRQYEMGECTRGGFCNFMHLKP ISRELRRELYGRSRKSRSRSPPTRRSRSRSRDRKRRRSRSRDGDKMFLTRSEYDRGVNTF SPEGRLFQVEYAIEAIKLGSTAIGIQTSEGIILAVEKRVTSSLIEPSSIEKIMEVDSHIG CAMSGLIADSRTLIDKARVEAQNHWFTYDEKISVQSIALAVSNLALAFGDDDADPGAMSR PFGVALLFAGIDERGPQLIHMDPSGTFTQCDAKAIGSGSEGAQQALQDTYHKSMDLKQAC VESLKILKEVMEEKLNSTNVEMAKITPAKGFQMFSKDELEEIIKEL-------------- --------------------------PHYFKHIKISALSLLKMVMHARSGGNLEVMGLLL GKVDGNTMLVMDSFALPVEGTETRVNAQAQAYEYMAAYTESANQVGRLENAIGWYHSHPG YGCWLSGIDVSTQMLNQQFQEPFVAIVIDPVRTISAGKVNIGAFRTYPKGYKPPDEGPSE YQSIPLNKIEDFGVHCKQYYSLEVSYFKSSFDRRLLESLWNKYWVNTLSSSSLLTNADYT TGQVFDLADKLEQSEAQLGRGGFIEKKSEDKLAKATKDGCKNTIEAIHGLMSQVIKDKLF NQVGGLPRRIIKETQRLKAEPVPGIEATPDESNARYFHVIVNGPKDSPYEGGTFKLELFL PEEYPMLAPKVRFMTKIYHPNIDKLGRICLDILKEKWSPALQIRTVLLSIQALLSAPNPD DPLANDVAEQWKIDEVRAISTAREWTEKFAEAENELLDYEEDEQEETKEVKGTYVSIHSS GFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVVCQAKSGMGKTAVFVLATLQ QIEPVENQVSVLVLCHTRELAFQISKEYERFSKYMSGIKIAVFFGGMNIKKDETVLKNNC PNIIVGTPGRILALIKHLNLKNIKHFVLDECDKMLEALDMRRDVQEIFRMTPHEKQVMMF SATLSEEIRPVCKKFMQDPMEVYVDDDSKLTLHGLQQHYIKLKDNEKNRRLFELLDALEF NQVIIFVKSVQRCMALAQLLVEQNFPAIAIHRALTQEERLAKYQQFKDFQKRILVATNLF GRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVS-------PPTYADLG KGARDLFSKGFNYGTYKLEVKTQTSNGVNFTTSGNSNHDSGKVGGNLETKYKYSDYGLTF VEKWNTDNVLGTEITIEDQMLKGLKLSFDTSFAPQTGKKSGKIKTAYKQDYVNAGCDVDF DFAGPTINGAMVLGYQGWLAGYQMAFDKSKLAKSNFAVGYTTGDFTLHTSVNDGSDFTGA VFQKVNRDLEAGVQLNWTAGSNATKFGLAAKYTPDRDTTIRAKVNNNSQIGLAYQQKIRD GVSLTLSTLLEGKNFNQGGHKVGLGLDFEADTVREKALQDYRKKLLEHKELEARLKEMRE QLKDLTKQYDKSENDLKALQSVGQIVGEVLKQLSEDKFIVKATNGPRYVVGCRRQIDKSK LKSGTRVALDMTTLTIMRYLPREVDPLVYNMSIEDPGDIGYSAIGGLGEQIRELREVIEL PLLNPELFERVGITPPKGCLLYGPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIGES ARLIREMFGYARDHQPCIIFMDEIDAIRRFSEGTSADREIQRTLMELLNQMDGFDALGKV KMIMATNRPDTLDPALLRPGRLDRKIEISLPNEQARMEIMKIHAGPIAKHGEIDWEAVVK LSDDFNGADLRNVCTEAGMFAIRSERDYCVEEDFMKAVRKVCDNKKLESKLDYKPLMPDS LKSVVCKFYDEYMKTTPKRLKVIDAYLFYVILTGVIQFGYCALVGTYPFNSFLSGFISCV GSFVLAACLRVQANPQNKSDFLSISPERAFGDFIFAHVILHLVVMNFIG----------- ELVDKCIGSKIHIVMKNDKEIVGTLLGFDDFVNMVLEDVVEYETTAEGRRVTTLDQILLN GNNITMLVPGGEGPDVIDHYENPRNVGSMNKKDKNVGTGLVGAPACGDVMKLQIKVDDDG KIIDAKFKTFGCGSAIASSSLATEWVKGKTLDEASSIKNTQIAKELCLPPVKLHCSMLAE DAIRAALQDYKVKNDILVLVLGDLHIPHRSISMPGKFKKLLVPGKIQHILCTGNLCTKES FDYLKTLASDVHVVRGDFDENMNYPEQKVVTVGQFRIGLCHGHHVVPWGDIESLAVVQRQ LDVDILISGHTHKFEAFEHENKFYINPGSATGAYNAIEQNVTPSFVLLDIQQSTVVAYVY QLLGEDVKVERIEYKKMGKFLKSGKVVLVLGGRYAGRKAIIVKNYDDGSSDKPFGHALVA GIERYPRKVTKSMGKKTLKKRSKIKTFVKVYNYNHLMPTRYSVVPLDKQAVNKDAFRDPA LRRKARREIKAKFEDRYKSGKNKWFFQKLRFERTFIMIKPDAVHRGLVADIIKRFEQKGF KLVAMKFMQASEELLKTHYADLSSKGFFPGLVKYMSSGPVVPMVWEGGAVLTGRKMLGAT NPAESQPGTIRGDFCIEVGRNICHGSDSVDSANREIDLWFKPDEQVNWSKAEKPWVYEAA APKPVKTDSSAKDKALKAKKTVLRGVHQSLKKKIRSKPRFTRPHTLRLPRTPKYPRKSTH HAPRMDQYKIIKYPLTTESAMKKIEDNNTLVFIVHQKANKPQIRMAVKKLYSIDVSKVNT LNRPDGEKKAYVRLAPDYDALDVANKIGIIMPSKQRMRLANEKHSKNIQNKGNVPKTLKA AEDKLPVGPWLLGLFIFIVCGSAVFQIIQSIRM-----YTAVATWRWVANDDNCGICRMP FDGCCPDCKVPGDDCPLVWGRCSHCFHIHCIVKWLNSQQVHQLCPMCRQEWKFKEQIRFI LIQNRAGKTRLAKWYMHFDNDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIVYRRYAGL YFCICVDVADNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYSVVDEMFLAGEIRE TSQTKVLKQLLMLSSLE-PTIFSKIIDRSIPAEILHEDDQCLAFRDIEPQSPVHFLVIPK KIIPGISCDQQLLGHLMLTAKKVAEAVKGYRVVINNGVEGSQSVYHLHIHVMGGRQMEWP PVSGLLSYFSGLFGSKERRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVVYKN LRFQVWDLGGQTSIRPYWRCYYSKTDAIIYVVDSMDRDRIGISKNELVSMLEEEELKKAT LCVFANKQDIEGAMTVTEVANALGLSSIKNRKYQIFKTSAIKGEGLDDAMEWLANALLSN -ALYFHIGETEKKCFIEEIPDETMVVGNYRVEMFDKMQQKYMPTTAGLGMHVEVRDPEDK NIMSRTYASEGRFTFTSHTAGEHIICLHSNSSAWFGGGQLRVHLDIQIGEHANDYQQIKA KEKLTELQLRMRQLLDQVEQITKEQNYQRYREERFRQTSESTNQRVLWWSIAQTLILVLT GFWQMRHLKGFFEAKKLVMFYHVSLEHEILLHPQYFGPNLLNTVKQKLFTEVEGTCTGKY GFVIAVTTIDNIGAGIIQPGRGFVLYPVKYKAIVFRPFKGEVLDAVVTQVNKVGLFTEIG PLSCFISRHSIPSEYEFDPNNNPPCYKTKDEDILIQTDNEIRLKIVGTRVDASDIFAIGT LMDDYLGVV-RLYVKAVFTGFKRGLRNQHEHTALLKLDGVESKRETGFYLGKRCAYVYKA KKKTPCPNHEKSSRIRVIWGKVTRSHGNSGAVRAKFSKNLPPRAMGKRIRIMLYMAKKTY DLLFKLLLIGDSGVGKTCLLFRFSDDAFNTTFISTIGIDFKIKTVELGGKKIKLQIWDTA GQERFHTITTSYYRGAMGIMLVYDITNAKTFDNISKWLRNIDEHANEDVEKMILGNKCDI EDKRQVPKQRGESIAREHGIPFLETSAKSNVNVEKAFMDLAQAILNKQPQNEHIEQHIRR HGRRLDYHEKKRKKESREAHERSKKAQGLKGLKAKIYHKKRQSEKVQMKRTIKMHQQRKT KQKTEENVPEGAVPAYLLDREGQTRAKVLSNMIKQKRKEKAGKWDVPLPKVKGVSESDVF KVVKTGKTRRKGWKRMVTKACFVGEGFTRKPPKYERFIRPMGLRVKKAHVTHPELKATFC LPILGVKKNPTSPMYTQLGVLTKGTIIEVNVSELGMVTQGGKVVWGKFAQVTNNPENDGC VNAVLLVMASRPLVSVHNEKGEKTTANITLPAVFKAQIRPDIVSFVHFEMKKNGRQPYAV SEKAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRR ININQRRYAMCSAIAATGIPALVMSKGHQINEIAEVPLVVDDKIEECKKAKEAVLCLRKL KAYADVEKVKDSRRFRAGRGKMRGRRRVQKRGPLVIYNQDNGLVKAFRNIPGITTLPVDK LNLLKIAPGGHVGRFCIWTESAFKKLDGLYGTWKKRSSEKTGYNLPMSKMTSTDLNRLLK SDEIQNAIRAPNKSVTRRTQKKNPLKNHLLMEKLNPYSRVQKKAARRQKKKQALIDQKRG L----------------GSQEQELATKTLQIQSKRFYLDVKQNRRGRFIKIAEVGAGGKK SRLLLAMSTAAEFRDHLTDFSDHYASLGPPSQESVPEDGKLKSESMVKDNRRYYLDLKEN QRGRFLRVSPRSVNRSQIAIPAQGMIEFRDALTDLLEEFGTDDHESQGELPEPKSMRVEH KMFYFDVGQNRRGTFMRISETNFRTAITIPERSWGRFRDVLSSFVES------------- INRKLVESGERERLKELLRERLIECGWRDQLKAHCKDVVRQKGLENITVDDLVAEITPKG RSLVPDQVKKELLQRIRSFLASQTNMNIRNASPEDLMNMQHCNLLCLPENYQMKYYLYHG LSWPQLSYVAQDEKGKVVGYVLAKMEEDPDDAVPHGHITSLAVKRSHRRLGLAQKLMDQA SRAMVECFDAKYVSLHVRKSNRAALHLYKHTLRFEISEIEPKYYADGEDAYAMRRNLGEF LDKF-AHTILLVQPGRKPEGRTYSDYESVNECLEGVCKIFEEYLKRMNPNAPSITYDISD LFEFVENLSDLSCLVFEKTSGKYIPHNKAWIKEKIYILLRKQAGKMTEETAEKKEQETKR VVHTYPLIRHSDMAEEMRVEAMELCVTACEKFSSNNEVAAKMIKETMDKKFGASWHVVVG EGFGFEITHEVKNLLYMFFAGTMAICLWKCSMSHRKFSAPRHGSLGFLPRKRSTRHRGKV KAFPKDDPSKPVHLTSFLAYKAGMTHVVREVDRPGSKAHKKEVVDAVTILEAPPMIAIGV IGYIETPRGLRALKTVWAEHLSEECRRRFYKNWYRSKKKAFTKASKKWQDEVGKKEIEKD LAKMKKYCSVIRVIAHTQMKLLKKRQKKAHIMEIQVNGGTVAQKVDWAREHFEKQIPVDS VFAPDEMIDCIGVTKGHGFKGVTSRWHTKKLPRKTHKGLRKVACIGAWHPARVAFSVARA GQKGYHHRTEINKKIYRMGKGVHTENGKLIKNNGSTEYDVTEKTITPMGGFPHYGEVNQD FIMLGGCCMGPKKRVITLRKSLLTHTKRKALEKMNLKFIDTSSKFGHGRFQTHQEKRNFM GPLKKDMQNLKLVVVGDGGVGKSCLLISYATNSFPSEYVPTVFDNYSSNILVDGKAVNLG LWDTAGQEDYDRLRPLSYPLTDVFLLCYSVDNRDSLENIANKYKAEVDHHCPGTPQILVA CKRGELGKKDQSRFVSEN--------EGRRMAKSLG-IQFFETSALTQQGVAIAFDHAVA MSFCPKKKKK--------MFDTSMKKKKKKKTPFDLDAAEDDFSLDDNFTKKKKKKKKVF DMSEMETALPAKEKNLPKKKKKQNSDKDYTYDELLKRVFDIMRDKNPDMVAGEKKRFIMK PPQVMRAGAKKSSFSNFAEICKALHRQPKHLLAFLLSELGTSGSIDGSNQLIIKGRFQQK QIEHVLRRYIKEYVTCHTCRSPDTILQKDTRLYFLQCESCGSRCSVTSIKSGFQAVTGKR AAIRAKT-IDDAAEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPDGK DYSLHRLVLGTHTSDEQNHLLIASVQLPNDNAQFDATHYDSEKGEFGGFGSVTGKIEIEI KINHEGEVNRARYMPQNPCVIATKTPSSDVLVFDYTKHPSKPDPSGECRPELRLKGHQKE GYGLSWNPNMNGNLLSASDDHTICLWDINTTPRDNKCIDAHSIFHGHTSVVEDVAWHILH ECLFGSVADDQKLMIWDTRSNNTNKPSHIVDAHTAEVNCLSFNPYSEFILATGSADKTVA LWDLRNLKLKLHSFESHRDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQSAEDA EDGPPELLFIHGGHTAKISDFTWNPNEPWVICSVSEDNIMQVWQMAENIYNDEEPDTPAQ DLEMPAPSRARVYADVNTHRPREYWDYESHVVEWGQQDDYQIVRKLGRGKYSEVFEAINV TNNEKCVIKILKPVKKKKIKREIKILENLRGGTNIITLLAIVKDPVSRTPALIFEHVNNT DFKQLYQTLTDYDIRFYIFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLA EFYHPNQEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPFFHGHDNY DQLVRIAKVLGTEELFEYIDKYQIDLDPRFNDILGRHSRKRWERFVHSENQHLVTPEALD FLDKLLRYDHQERLTAREAMDHPYFYPIVKEKVPETLLKKRKRTAEKRRTTRKVIFKRAE KYVKEYRLKERDQIRFARDARKHGNFYVPPEPKVAFVMRIRGVNGVAPKPRKVMQLFRLR QINNGTFVKLNKATLQMIRLADPFITWGYPNLKSVRELIYKRGFGKVNGCRVPLADNAII EEKLGKFGIICMEDLIHEIFTCGPNFKAANNFLWHFKLNTPTGGWRKKNNHFVDGGDFGN REYKINDLLKRMMQFMLLFSRQGKLRLQKWYEAHPDKLKKKITRELITTILARKPKMCSF LEWKDMKIVYKRYASLYFCCCVEADDNELLTLEVIHRYVELLDKYFGSVCELDIIFNFEK AYFMLDELLLGGEVQETSKKNVLKAIAAQDLLQEEEPQGILEELGL-MSKAHPPELKKYM DKRLTLKLNGGRVVTGTLRGFDPFMNLVVDEAIEQCKTGEQNSIGMVVVRGNSITLLEAL DRVEFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDKTI RLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFQQTSKWIDDVRTERGTDVIIM LVGNKTDLSDKRQVSTEEGERKAKELGVMFIETSAKAGYNVKQLFRRVAAALPGMEQKEA TKNIVLEPYEVPLHLYK----YQMAVGLKKGYTVSNPKPRLSRRTGTMTKHNKFIRDVVR EVCGFAPYERRVIELLRISKDKRALKFCKKRLGGHVRGKKKREEMQSVIMQMRKAMVDAA TKKTLAKIPLLKTKAGPRDGDLWVQRLKEEYQSLIAYVQNNKEADNDWFRLESNEAGTRW FGKCWYFDNLLKYEFDVEFDIPITYPTTAIEIALPELDGKTAKMYRGGKICLTDHFKPLW ARNVPKFGLSHAMALGLGPWLAVEIPDLISKGIISHK-FIDNLDFLDDVRRMNKRQLYYQ VLNFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFFRGDLLFLTNYKEEPIRVGE IVVFKVEGREIPIVHRVLKVHEKEDGSVKFLTKGDNNQVDDRGLYAAGQHWLQKKDVVGR ARGYVPYVGTVTILMNDYPKFKYLILASLGIFVLIHRE----NPEYDYLFKLLLIGDSGV GKSCLLLRFADDTYTDSYISTIGVDFKIRTIELDRKTIKLQIWDTAGQERFRTITSSYYR GAHGIIVVYDVTDQESFNNVKQWLQEIDRYASESVNKLLVGNKCDLTTKKVVDYTTAKEY ADQLGVPFLETSAKNATNVEQAFMTMAAEIKNRMGPVAAAPNVKINASTPVKQGGGGCC- ------------------------------------------------------------ ------------------------------------------------------------ ------GVNKDSYLILETLPAEFDSRVKAMEVDERPTEQYSDVGGLDKQIQELIEAVVLP MTHKERFETLGIQPPKGVLLYGPPGTGKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGA KLVRDAFALAKEKAPAIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNHD IKVIAATNRVDILDPALLRSGRLDRKIEFPVPTEEARARIMQIHSRKMNVNSDVNYEELA RCTDDFNGAQCKAVCVEAGMIALRRGGTELSHEDYMDAILEVQAKKKANLNYYAKDAADQ NFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRQDKRVKLQIWD TAGQERYRTITTAYYRGAMGFILMYDVTNEESFQAVQDWCTQIKTYSWDNAQVVLVGNKC DLEDERVVSFDRGKQLAEQLGLEFFETSAKENINVKAVFERLVDIICDKMSESLDTDPTQ TKRLTENPNPQNSGCQC-----------------LAYKTVSGVNGPLVILDDVKFPKFAE IVRLTLADGTERSGQVLEVSGSKAVVQVFEGTSGIDAKHTTCEFTGDIMRIPVSEDMLGR IFNGSGKPVDKGPPVLAEDYLDIQGQPINPWSRIYPEEMIQTGISAIDGMNSIARGQKIP IFSAAGLPHNEIAAQICRQGGLVKLPSKGVFDDHEDNFAIVFAAMGVNMETARFFKQDFE ENGSMENVCLFLNLANDPTIERIITPRIALTSAEFLAYQCEKHVLVILTDMSSYAEALRE VSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRGGSITQIPILTMPNDDITHPIPDLT GYITEGQVYVDRQLHNRQVYPPINVLPSLSRLMKSAIGEGMTREDHSDVSNQLYACYAIG KDVQAMKAVVGEEALTPEDLLYLEFLQKFEKNFISQGPYENRTIFETLDIGWQLLRIFPK EMLKRIPQDKLAKYYPRDAEGPGYVGIKFCQECNNMLYPKEDKDSRVLLYACRNCEYKQE ADNPCIYVNKIQHEVDELTQIIADVVADPTLPRTGDHPCPQCGHKEAVFFQSQSRRAEEG MRLYYVCSLANCMHRWTEKPQYKVADISLAEWGRKAIELAENEMPGLMMLRKVYGPKKVL KGARIAGCLHMTVQTAVLIETLTELGAEVQWSSCNIFSTQDHAAAAIAKTGVPVYAWKGE TDEEYLWCIDQTLVFADGKPLNMILDDGGDLTNLVHTKYPQYLKDIRGLSEETTTGVHNL AKMMAKGELKVPAMNVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGKVAVVAGYGDV GKGCAQALRAFGSRVIITEIDPINALQAAMEGYEVTTMDHAVQEAHIFVTSTGCADVLTG EHFSQMQDDAIVCNIGHFDCEIQVKWLNENCASKDTIKPQVDRYTMKSGRHIILLAEGRL VNLGCAMGHPSFVMSNSFSNQVLAQIELWTKHGEYPIGVHLISKKLDEEVAAAHLDKLGV VLTKLTSQQSEYLGIPVEGPFKPAIYRY----------TVEEPLDLVRLSLDERIYVKMR NDRELRGRLHVSNS-LN--------------------------TKRIIPMLFVRGDGVIL VSPPTRT----NLENVSPQIIRQVAKEIGDLQKEPPEGIKIIPNDEDLTDLQAAIEGPAG TPYAGGYFRVKLVLGKSFPSEPPKGFFLTKIFHPNVAKNGEICVNTLKKDWKAEYGIKHI LLTVKCLLIVPNAESALNEEAGKMLLEQYDDYSMRAKMYTDIHAKPMFKSMIESARTSPF SSPFGLKVNENRTIAAP-ADESCEFGSGKYYALCGLGGILSCGITHTAVVPLDLVKCRIQ VDPAKYTGVFQGFRLTVKESGIRELGKGWAPTFFGYSAQGLCKFGFYEVFKNVYSGILGE EKSFLWRTSLYLAASASAEFFADIALCPMEAVKVRIQTQPGWASTLREGFPKLMAEEGVN GFYKGIVPLWARQIPYTMMKFACFERTVEALYKFVVPKPRADCSKAEQLVVTFCAGYIAG VFCAIVSHPADTIVSKLNKEKGSSFGEIARGLGFAGMWKGLVPRIIMIGTLTALQWFIYD SVKVYFRLPRPPPPEMPESLKRKLAHWVNERVIAVALLPIIPVALAFVLDNVLASVMLHT HWRLSGVVGDYIHVSICALGGLLYFNYTDIGFANAVRMIYTELNDQPEEDSSELIFPKEF ENAETLLISEVYRAQQNENAEDEQELSEVFKKTLTHTERFKKFKNRETIASVRSLLMQKK LHKFELAALANLCPETAEEAKALIPSLEGRFEDEALQQILDDIKTKISFQ-TLQPHLSKQ DLDKLNICDLTPLTHEVISRQATINIGTIGHVAHGKSTLVKAISGVQTVRFKNELERNIT IKLGYANAKIYKCDDPSVQRPACYTSRGSSHVDEFPCDVPGAAKFKLIRHVSFVDCPGHD ILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILIMQNKIDLVKESQ AKEQHEQIQRFVQGTIAEGAPVIPISAQLKFNIDAVCEYVVKNIPVPVRDFTSEPRLIVI RSFDVNKPGCEVMDLKGGVAGGSLLRGVLRVGQEIEVRPGIVSKDAEGKLTCKPIFSRIV SLLAEQNDLQYAVPGGLIGVGTKIDPTLCRADRMVGQVLGAVGCLPNIYTELEISYFLLR RLLGVRTEGDKKGAKVQKLSKSEILMVNIGSLSSGGRVQAVKADLAKILLTSPVCTEIGE KIALSRRVEKHWRLIGWGQIRRGVTVKPMAELLLDSDIRIWVFLPIVLITFLVGIIRHYV ATLMTSEKTVEIQQIKDSQALIRSRMLRENGKFLPRASFEMRKHYFNNKDDGYFVKNPMT DPTMMADMMKGNVTNVIPMIVIGGWINWAFSGFLTTKVPFPLTLRFKPMLQRGVELSALD ASWVSSASWYFLNVFGLRSMYNLILGQDNAADQTRMMQDQMTGAAMGMPPDPSKAFKAEW EALEISSHKWALEQIEDELVMFLWDWFAGVLNFLGLYKKSGKLVFLGLDNAGKTTLLHML KDDRMAQHVPTLHPTSEELSMGGMRFTTFDLGGHQQARRVWKDYFPAVDGIVFLVDAFDR ERFVEAKAELESLLSDEQIAAAPVLVLGNKIDIPGAASEDEIRHLFGLHGQTTGRGNIPR SEVRPMELFMCSVLKRQGYGEGFRWLAQYINIVRRNRPGTKATEWSNWPDEVFDEMDSTL AVQQLIQQAIRHDFGNIDEILTPPDGQDEGVWKYEHLRQFCMELNGLAVKLQNECNPDSC PQMTATEQWIFLCAAHKTPKECPAIDYTRHTLDGAACLLNSNKYFPSRVSIKESSVAKLG SVCRRVYRIFSHAYFHHRELFDEYENETALCRRFTIFVTNYNLMSKDNLIVPILEEQMPN IKLQSSDGEIFEVDVEIAKQSVTIKTMLEGDEDEEEVVPLPNVNAAILKKVIQWCTYHKD DPPPSEDDENKEKRTDDISSWDTEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMI KGKTPEEIRKTFNIKCDFTPTEEEQVRKENEWCEEKNKRVVKGGKKGGKKKVVDPFTKKD WYDVKAPSMFNIRQVGKTVVNRTVGTKLAADGLKGRVFEVSMADLQDDEVAFRKFRLIAE EVQGRNVLTNFHGMSLTTDKLRSMVKKWQTLIEGNVAVKTTDGYMLRLFCIGFTNRRQNQ IRKTSYANSHQVRLIRKKMTDIMVREVSSSSLKEVVNKLLPDSIGKDIEKACQGIYPLHD VYVRKVKILKKPKLDLGKLLEMYGDGPSKATGESGEKVDRADGYEPAVQASVMSASAVYI LDVKGKVMICRNYRGNIDMSIIDNFMPLVMDKEEEGVSAPIIQYGNITFIYIKCNNLYLV ATTKKNANVALVFQFLHRCVQVFSEYFKELEEESIRDNFVIIYELLDEVMDFGFPQTTDS KILQEYITQEGHKLEVAPRPPMAVTNAVSWRSEGIKYRKNEVFLDIIESVNLLVSGSGSV LRSEIVGAVKMRVYLSGMPELRLGLNDKVLFESTGRGKSKSVELEDVKFNQCVRLSRFEN DRTISFIPPDGEFELMSYRLNTHVKPLIWVESVIERHAHSRIEFMIKAKSQFKRRSTANN VEIVVTVPTDADCPKFKTTAGSCRYAPDQNAMIWTIKSFPGGKEYLMRAHFGLPSVVNED LEGKAPIHVRFEIPYFTVSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRT-MGILEK IAEIENEMAKTQKNKATSGHLGLLKARLAKLKRELIEPKGGGGGAGEGFDVAKTGDARVG FVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGCIRYKGAKIQLLDLPGIIEGAKDG KGRGKQVIAVARTCSLIYIVLDVLKPLQHKKLLEYELEGFGIRLNKQPPNISFRKKDKGG INLTATVTQSELDLDLVRSILGEYKIHNADITLRFDATTEDLIDVIEGNRVYVPCIYVLN KIDQISVEELDIIYKIPHCVPISAHHKWNFDDLLEKMWEYLALTRIYTKPKGQLPDYNSP VVLRNGKTTLEDFCLKIHKSILKELKYGMVWGSSVKHQPQKVGKEHTLNDEDVVQLVKK- ----------------AIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGSYQGRCVTC GGPGVSDAYYCKECTITEKDRDGCPKIVNLGSAKTDLFYERKKYGFKKRPNLPPISSDKI SAKKEFRKIPVPSNRYGPLKENWMKIFTPVVEYLHLQIRFNLRTRHVEIKTCKETKDIGA LQKAADFVKAFILGFDIEDGLALVRLDDLYLESFCVTDVKPLKGDHLSRAVGRIAGKGGK TRFTIENVTRTRIVLADTKIHLLGSFQNIKIARRAISNLILGSPPSKVYGTMRVVAARSA ERRVKVANPVVELDGDEMTRIIWSFIKEQLVFPYVDVDAHYYDLGLPHRDATDDQVTIDS ALAMMKHNVGIKCATITPDEERVEEFKLKKMWLSPNGTIRNILGGTVFREPIICKTIPRL VPGWTNPIVIGRHAHGDQYKATDFVAQGNGKLELTFTPEDGSATVMPVFDFKKGGGVGMA MYNTDESIAGFGHACFQYALKKKWPLYLSTKNTIMKRYDGRFKDIFQDIYEAEYKKDFDA AGIWYEHRLIDDMVAQALKSDGGFVWGCKNYDGDVQSDVVAQGYGSLGLMTSVLMCPDGK TVEAEAAHGTVTRHYREHQKGNATSTNPIASIFAWTRGLEHRALLDNNPDLTRYCQLMEK ACVDTVDNGKMTKDLAGCIHGLKNVTTDHYLNTTDFLEAIKEQFDMGKLLSKIFGNKEMR ILMLGLDAAGKTTVLYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWR HYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMKPHEI QEKLGLTRIRDRNWYVQPSCATTGDGLYEGLTWLTSNAKSFGDLKSNAGLKVLNEFLADK SFIQGFVPSQADVAVFEAMSGPAESFVNALRWYNQIKSYGSQKSSLPGVKGTVDSYGPAG ASKDDDDDDFDLFGEEAQRIKDERIAAYQAKKSPALIAKSNVILDVKPWSDETDHAEMEK CVRSIEMDGLLWGASKLVPVGYGIKKLQIATVIEDDKVSTDDLIEQICEFEDHVQSVDIA AFNKIKVQEVREVTRIERIGAHSHIRGLGLDDALEARNVSQGMVGQTSARRAAGIILEVI KDGKIAGRAVLIAGHPGTGKTAIAMGMAQALGTDTPFTSIAGSEIFSLEMSKTEALTQSF RKSIGVRIKEETEIIEGEVVEIQIDRPATGTGAKVGKLTLKTTEMETIYDLGQKMIESLT KEKVQAGDIITIDKATGKITRLGRSFTRARDYDAMGSQTRFVQCPEGELQKRKEVVHT-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------MAAFDLTTSMGKYLDRHLVFPLLEFLSNK QIYDETEMQKGKLDLLKSTNMVDFAMDVHRSLYPDQEVPESLQEKRTQVLSELKGLTVET EPVSRILEKEEVMIQSTRDGRTLFNFLTEKHGFNDGMLETLYKYSKFQYECGNYSGAAEY LYFVRALLPPGNKNYMNALWGKLASEILMQNWDAALEDLNRLREVIDSSLQSLQQRTWLI HWSLFVFFNHPKGRDLIIDLFLYQPLYLNAIQTMCPHVLRYLTTAVITNKTVLKDLVKVI QQESYTYKDPITEFLECLYVHFDFDGAQQKLRECETVLVNDFFLVACLRDFIENARLFIF ETFCRIHQCISITMLADKLNMGEEEAERWIVNLIRNARLDARIDSKLGHVVMGTQAVSPY QQVIEKTKGLAFRSQMLVMNIEKKI----MGVELETIQPGDGCTYPKDGQIVEIHYTGTL SNGKKFDSSRDRGAAFKFTIGKDQVIKGWDEGIKKMSIGQRVKLTCSPDYAYGKRGFPGV IPPDSTLYFDVELIGL-MPKYFCDYCDTFLTHDSPSVRKTHCNGRKHKDNVRDYYQKWLE DQVQKLVDDTTAAFKAGKIQNNPFSAGGAAIPPPASLA--PPAP-MSMMGPPPPG----M R----PMGPPMPMGGPPEPLTLERDVKRAVELLDILQKSGDLHKLASLQKVLQSEFCSAV REVYEHVYETVDISGSPEVRANATAKATVAAFAASEGHAHPRVVELPKTEEGLGFNVMGG KEQNSPIYISRIIPGGVADRVGGLKRGDQLLSVNGVSVEGEPHEKAVDLLKAAQGTVKLV VRYTPKVLEEMEARFDKQRTARRGQLCCLAVSAIADPAVYFQEDFWEDRWVQSEHK-ADL GKFVLSHGKFYGDAEKDNGIQTSQDARFYALSAKFDKPFSNEGKTFVVQFTVKHEQSIDC GGGYVKIFPSDVDQKDMHGESPYNIMFGPDICGPGTKKVHVIFTYKGKNLLIKKDIRCKD DVFTHLYTLIVRPDNTYEVKIDNKKVESGSLEEDWDFLQPKTIKDPNAKKPEDYDERETI DDPEDVKPEEWDQPEHIADPDAKKPDDWDDEMDGEWEPPMVDNPEYKGEWKPKQIPNPSY QGKWVHPEIDNPDYEADDSLYKYADFGVIGFDLWQVKAGTIFDNVLLTDDEALAEKVGEE TWGASKDAEKAMKDAQDEEEKAAREEEEKRRKEEEGDD------MDAPMPDPSLYCVKAI LILDNDANRLIAKYYDDTYPTAKEQKNLFSKTHRANAEIIMLEGLTCIYRSNVDLFFYVI GSQSENELILASVLNCLYDAVNTMLRKNVEKRALLDNMDAVFLAVDEICDNGIIMESDAS AVVNRVSFRSDDLPLGEQTVASVLQSAKEQIKWSLLKMNVFRLTGDIAHLLAIILLLMKI WKTRSCAGVSGKSQMMFALVFTTRYLDLITNFISLYNTTMKMIFIASSYGTLYLMFLKFR ATYDSNHDTFRMEFLVVPVAGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGE AETITSHYLFALGSYRALYILNWVYRFYFEGFFDLIAVVAGCVQTVLYCDFFYLYITKVW KGKKLTLPAMKIEEVKSTTKTQRIAAHSHIKGLGLDEAGFAIQTSSGLVGQEHAREAAGI VVEMIRSKKMSGRAVLLGGPPGTGKTAISLAIAQELGNKVPFCPMVGSEVYSTEIKKTEV LMENFRRAIGLRIKETKEVYEGEVTELTPVETENPMGGYGKTVSHVVIGLKTAKGTKQLK LDPSIYESLQKEKVETGDVIYIESSSGAVKRQGRSDTFATEFDLEAEEYVPLPKGEVHKK KEVIQDVTLHDLDVANAKPQGGQDIISMMGQLMKPKKTEITDKLRKEINKVVNKYIDQGI AELVPGVLFIDEVHMLDIECFTYLHRALESTIAPIVIFATNRGKCTIRGTEDMVSPHGIP LDLLDRLMIIRTLPYSQEEMQQIIRIRAQTEDISVSEESLAKLASIGVKSTLRYAVQLLT PCSLLAKINAKESIGDDDIQEINELFFDAKASAKILADQDDKYMKEFEVDDEGDKDLQKL KEKVKKRKGRGFETKTDVEAYEGMETGAPGPQRSVEGWILFISSVQEEAQEDDIMDKFSE YGNIKNVHLNLDRRTGYLKGYSLVEYDTYNEAQSAMENLNGTEILGQKINVDWAFVRGPS KQKMSYQLYRNTTLGNTLQESLDDLIQCGQITPELALKVLQQFDEAINTALSTRVKNKVT FKGHLNTYRFCDNVWTFVLDDVEFKTVDKVKIVACDGKGSFLFTSESVGEGHPDKICDQI SDAVLDAHLKQDPNAKVACECAAKTGMIMLLGEISSKAHVDYQKVVRDTIKYIGYDDSCK GFDYKTCNVLSALEEQSPDIAHGVHVGRDEDDIGAGDQGLMFGYATDETEECMPLTVVLA HKLNAKIAELRRNGGLAWARPDSKTQVTCEYRMIKGACVPMRVHTVVISLQHSEDVTTEQ IRSDLLEKVVRVVIPEKYLDAKTVYHLQPSGRFVIGGPQSDAGLTGRKIIVDTYGGWGAH GGGAFSGKDFSKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVAHPLSVFVSSYGT GVKSDAELLDIVNNNFDLRPGVIVKELELKRPIYQATASYGHFGRSDFTWEQPKKLTYMA GSALKRLMAEYKQLTLNPPEGIVAGPVNEDNFFEWEALITGPEDTCFEGGVFPARLTFPS DYPLSPPKMKFSCDIFHPNIYADGRVCISILHAPGDDPMGYESSAERWSPVQSVEKILLS VVSMLAEPNDESAANVDAAKTWREDREKFNDIAHSTVRKSIGLMRLEKCYFCSSTVYPGH GINFVRNDCKIFRFCRSKCHKSFKKKRNPRKVKWTKAFRKSSGKELTVDPALEFEKRRNV PVKYDRKLWKETVNAMKKVEEIKIRRQNQHIINRLKKGKELRKADDFREVEKNLSLIRAP ---MAKYTVVMIRHGESTWNKENKFCGWFDADLSELGENEARTGGKMLKEKGYTFDIAFT SMLKRAIKTLHLVQDELDLMWIPVVKHWRLNERMYGGLQGLNKSETAAKHGEEQVKIWRR SYDTPPPVVDANSSHNPANDIKYKFVDKQLIPKSECLKDTVARALPFWYDQIVPAILSGQ KVLIAAHGNSLRAMVKYLDNMSEADIMALNIPTGIPLVYELDADLKPVKHYYLASDDQVK AAMDKVAAQGKAKMELQDSYYTKSEYIETASGNKVSRQSVLCGSQNIVLSGKTIVMSECI VRGDLANVRVGRHCVIGRRSVIRPPFKKFSKGVAFFPLHIGDHVMIEDDTIINAAQIGSY VHIGKNCVIGRRCILKDCCAIADNTVLPPETVVPSFTVFSGSPGMSFLFGGRSNKTFKPK KNIPEGSHQHELMKHAAATLGSGNLRLAVMLPDGEDLNEWVAVNTVDFFNQINMLYGTIT EFCTESSCPVMSAGPRYEYLWADGNLIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKI GVAFPRSFQNSAKVILKRLFRVYAHIYHQHFGQVIQLEEEAHLNTSFKHFIFFVQEFDLV DKRELAPLQELIDKLT---MGIDISHKHKRKVVRKAPKSEDVYLRLLVKLYRFLARRTDA KFNKIILKRLFMSRTNRAPLSIHRLVRLMKKPGRENKVAVVVGTITNDVRIFEIPKMKVC ALHVTEEARARIIKSGGEIMTFDQLALKAPKGQRTVLVQGPRSQRESQKHFGAAPGLPHS HSKPHVRSKGRKFERARGRRASRGYK-DLKQGNIQGSYLVANTVQLLRSIISQSKWCKAK DLLDIIRSEGKRLMEAQPTETAVGNMVRRVLKVIRDEYMIEAINELIVELENSAQALEHI HSNEVITTVETFLKKKFQVIVAEFHGQELAVSLAKANIETTVITDSAVFAMMSRVNKVII GTHTVMANGGLKATGSSTIALAAQHHSVPLLVCAAMFKLSPQYLCSYDDGFNEFVSPEQI HNPVFDYVPPEL-------------------------MIIPVRCFTCGKVIGDKWETYLG LLQAEYTEGDALDSMGLKRYCCRRMLLAHVDLIEKLLNYAPLEKKSPEPVEGRKHIDVQT ELYLEELSDRVEEADVDCQTDAFLDRPPSPMFVPAKTGKDIATQILEGDLFDFNIEVKPI LEVLVGKTVEQSLLEVMEEEELANLRKQQRAFLELRMAELVEQQRLEEQERRHREEKERR MKQQKEVLRKEKETADKIAARAFAQSYLADLVPSVFGTLSENGYFFDPVERDVEEGFLPW LMDRVEDQMSKHILGRTMLDSIIREVVTVRNEAYNKMKARGQLREFKVIGRMMPSPKNPR PAMYQMHIFAPDYIVAKSRFWYHVTQLRKMKKTGGEIVCCQRVYEKRPLTIKNFGVWLRY DSRSGTHNMYKEYRDLTTEAAVTQCYRDMGARHRARAHSIQIMRVAPIAAGKCRRAGVKQ FHDSEIKFPLPHRVNRRLHHPRFTTTRPHTHFSAQQDMKDFWKKNQNRPNSPWMVYEWHF PMLTSLGHRFTGIGMGVALYGLSFGLFFAPGDFTTYLTAVQGFGLSPYIMFPAKAIMAFP LMYHYLNGIRHLSWDAGYGYKLGTQYRTGAFCVASLSY-SGAAALSAYRDQHFRGNRIEQ EKALLTSTTLYIGNLSFFTAEEQIHELFSRAGDVKRIIMGLDKYRKTPCGFCFVEYYTRS DAEMAMRFVNGTRLDDRIVRTDWDAGFKEGRQYGRGKSGGQVRDEYRTDFDTGRGGYGKM IQQKIKPNYTLKFTLAGHTKAVSSVKFSPNGEWLASASADKLIKIWGAYDGKFEKTISGH KLGISDVAWSTDSKMLVSASDDKTLKVWDVSTGKCMKSLKGHSNYVFCCNFNPQSNLIVS GSFDESVRTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID DDNHPVSFVKFSPNGKYILAATLDNQLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG KWIVSGSEDNMVFVWNLQTKEVVQKLQGHTDVVLCCACHPTENIIASAALESDKTIKLWR SDVMRIYKDIFSNDEMLADTFPGVVYKVKGKDDALIGGNASSGVNIVMNGKKDYMKHIKK YMGKVKAYEPHMGLPLLYWETPYMMYFKHGLLEEKVVAVEYDGGVVVGADSRTTTGSYVA NRVTDKLTKVSDYIYCCRSGSAADTQAISDIVSYHLSVHKAELNEEPLVHTGASIFQDLC YNYRDQLSAGIICAGWDKRKGGQVYSIPLGGMCVRVPFSIGGSGSTYLYGWVDSAFKEKM TKEECQKFVLNAVTLAINRDGSSGGICNLATISVDGVERQKFLHDDLPKFIAIAIVALLL LLCCCFCICKRCCRKKKDKDKKKGLKGAVDLGSVKILGNSYKEKVQPDLEELEVNMEDNE DAESTKSEVKLGKLQFSLDYDFQKGELAVGVIQGADLPGMDMSGTSDPYVKVYLLPEKKK KHETKVHRKTLNPVFNETFNFKVPYAEMGSKTLVFAVYDFDRFSKHDQIGQVKVPLNSVD LGRVVEEWRDLTSPESDSEKENKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSD PYVKLSLMLNGKRIKKKKTTIKKCTLNPYYNESFTFEVPFEQIQKVTMIITVVDYDRIGT SEPIGRVVLGCNSTGTELRHWSDMLANPRRPIAQWHTLQEMPEK-MVLADLGRKITTALR SLSSATVINEEVLNSLLKEICTALLEADVNIKLVKKLRENVKSVIDFDEMAAGLNKRRMI QSAVFKELVKLIDPGVKAWQPTKGKNNIIMFVGLQGSGKTTTCTKLAYYYQKKGWKTCLI CADTYRAGAFDQLKQNAIKARIPYYGFMTKGNEQESMARLKKLMTIMDS----------- ----------------------NDSELDSHE--GAKLF-RGRVQRVARGAGVSCNEVEEL LKQKFAQMVKKMGGIKGLFKSGGDMAKNVPTQMAKLNQNIARMMDPRVLQQMGGMSGLQN MMRQFQAGAMSILSYNGSAIVAMAGKDCVAIAADRRFGIQGQTVALDFQKIYEYGPNLYM GLPGLATDVQTVAQRLKFRVNMYELRENRKMKPQTMLSVVSNLLYERRFGPYFVEPVIAG LDPKTSKPFIASLDLIGCPMITEDFVINGTCAEQLYGMCEALWEPDMSPDVLFEKVSQAM MSSCDRDAISGWGVVVHIIEKDKVTTRTLKARMDMTSKDYYFDSYAHFGIHEEMLKDEVR TLTYRNSMFHNRHLFKDKIVLDVGCGTGILCMFAAKAGAKKVIGIECSSIVEYAGKIVKA NKLDHIVTLVKGKVEEVALPDGIEKVDIIISEWMGYCLFYESMLNTVLYARDKWLAPGGL IFPDRATLYVCAIEDRQYKDEKINWWDNVYGFDMSCIRRVAISEPLVDVVDPNQVVTNAC LVKEVDIYTVKEGDLEFSAPFHLQCKRNDYVQAFVTYFNVEFTKCHKRTGFSTGPESRYT HWKQTQDYMTVKAKEEIFGIFSMKPNKRNTRDLDMSVEVDFRGELSALTDTFTYKMRMVR EDKSSWKASYFLKLIELIDEYPKCFLVGVDNVGSKQMQQIRIALRVLMGKNTMMRKAIRS HLENNPSLEKLLNYIKGNVGFVFTKGDLTEVRKIIQENRVGAPAKAGALAPLSVMVTARN TGLGPEKTSFFQALAIPTKITKGTIEILNDVQLIKEGEKVGASEATLLTMLKIMPFSYGL VIQQVYDSGTVFHPSILDMSDDDIRGKFMSGVSRVASLCLAIGYPTLASVPHSVVNGFKN LLAVAAATDVEFKEAETVKE---KGKLMAVIGDEDTCTGFLLGGIGELDKHRRPNFLVVD KTTSVSEIEEAFNKFVGRGDIAIILIGQNIAEEIRHILDAYKEPIPAILEIPSKDHPYDS SKDSILRRAKGMFSAEDFRGNEVTLPMELCSTFDADEIKRLGKRFKKLDLDNSGSLSVDE FMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKESKLRFAFKIYDMD KDGFISNGELFQVLKMMVGNNLKDAQLQQIVDKTIIHADTDGDGKISFEEFCSVVGSLDV HKKMVVDVMTYFTSWEEYAKAVEKLYVSDPNKCRFVTKYIHSKGQLCLKMTDDVVCLQYR TEHTQDIKKMEKLISQLMRHMASKELMEEVKLYRSARERENYDNIADLYAVVNTLQCLEK AYIKDSVTPKEYTAACSKLLVQYKAAFKQVQGEEFPSIEAFVKKCRLDCPAALERIKEDR PITIKDDKGNTSKCIADIVSLFITIMDKLRLEIRAMDEIHPDMRELMETMNRLSLLPADF EGKVKVRQWLDTLGSMQASDELTDVQVRQMLFDLESAYGSFNGVLHNMLSSMLKEHQSKQ NLRKEIQEKKKRDATAASALTHALVDHLNAGVAQSYVNQKKLDTETKILQANASHFARQT LLWLKLVEDFNQSLKEIGDVENWARSIETDMRIISNALDHAYKPKTVEKKIGGEKNGGTR KVTLPRQCRYYPTQEDPRKIKGPFKDHKRKIRSSITPGTILILVAGPHKGKRVVFLKQLA SGLLLVTGPYFVNGCPLRRINQIYVIATKTKLNIDSVTLPDRLTDDYFRRQKLNKAKMGE GDIFESKKEVYSVSEERKEDQSSVDKQLLAAIRKSGEKKLILGYLGAMFSLSKKQFPHKM IFLEWLFGKKKTPQEVLRQNQRALNKAMRDLDRERQRLEQQENKIKIDIKKMANQGQMDA VKIMALDLVRTRNYVKKFIVMKANIQAVSLKLQTLKCTDTMAQAMKGVTKAMVAMNKQLK LPQIQKIMMEFEKQTEIMEMKEEMMNDVIDDTMGEENDEEESEAIVGQVLNELGLQLGEE VSELPGAGKK-DKSPEGISDADADLEARLENLRRQSRYCDFCLGDDIENKKTGMKEELVS CADCGRSGHPSCLQFTANMIISVKKYPWQCIECKSCGLCGTSDNDDQLLFCDDCDRGYHM YCLNPPLSEPPEGSWSCHLCIREFYG--------YPLTNYTFGTKEALYEKDASVQERFK RMRQEFADNGMRRTAEGVLIVHEHGLPHVLLLQLGTTFFKLPGGELKNGEDQTEGLKRLL TEMLGRQDQAPTDWTIEDTIGNWWRPNFEPPQYPYIPAHITKPKEHKRLFLVQLPEKALF AVPRNYKLVAAPLFELYDNSAGYGPIISSLPQALSRFNFIYNFTPSGATPTGARAMVMAT PNPSQLMSMTPEQMQAYTLQRELDERNRPLSDDDLDTMLPPGYKVLQPPAGYIPIRTPAR KLTATPTPMASTPTGFKMQSVMIDLQAKGNMPMLKPDDMQYFDRKIMQMLLKIKNGTPPM RKSALRQITDKAREFGAGPLFNQILPLLMSPTLEDQERHLLVKVIDRILYKLDDLVRPYV HKILVVIEPLLIDEDYYARVEGREIISNLAKAAGLATMISTMRPDIDNMDEYVRNTTARA FAVVASALGIPSLLPFLKAVCKSKKSWQARHTGIKIVQQISILMGCAILPHLKSLVEIIE HGLIDEQQKVRTITALALAALAEAATPYGIESFDSVLKPLWKGIRTHRGKGLAAFLKAIG YLIPLMDAEYANYYTREVMIILVREFQSPDEEMKKIVLKVVKQCCATDGVEPQYIQDEVL PPFFKHFWNQRMALDRRNYKQLVDTTVEIANKVGSAEIISRIVDDLKDEAEQYRKMVMET IEKIMSSLGAADVDSRLEEQLIDGILYAFQEQTTEDVVMLNGFGTVVNSLGKRVKPYLPQ ICGTILWRLNNKSAKVRQQAADLISRIAIVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLG SILGALKGIVNVIGMTKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGAEFVS AREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVC TTVAIAIVAETCSPFTVLPGLMNEYRVPELNVQNGVLKSLSFMFEYIGEMGKDYVYAVTP LLEDALMDRDLVHRQTAMAAIGHLALGVYGFGCEDALTHLLNHVWPNVFENSPHVVQAFM GAVEGMRVGLGAPKVLQYTLQGLFHPARKVRDVYWKVYNTMYIGAQDSMVPAYPRIPNDE KNLYLRYELDYILDDFMVDDEDYDLEYSEDSNSEPDVDLENQYYNSKALKDDDPRAALES FQKVLDLEGKDKGEWGFKALKQMIKINFKLGNVAEMMARYKQLLLYIKSAVTRNYSEKSI NSILDYISTSKQMELLQNFYETTLEALREAKNDRLWFKTNTKLGKLHFDREDWNKLQRIL KQLHQSCQTADGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYKQSLHIKSAIPHPL IMGVIRECGGKMHLREGEYEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGIN PFDSQEAKPYKNDPEILAMTNLVSSYQNNDINEFEKILRTNRRNIMEDPFIREHIEDLLR NIRTQVLIKLIKPYTRIHIPFISKELNIDVCEVENLLVSCILDNTVSGRIDQVNQVLELN LGSARYNALDKWTSHLSSLHQAVVNKMAVLLMGKSGAGKTSMRSIIFANYIARDTRRLGA TIDVEHSHVRFLGNLVLNLWDCGGQEAFMENYFASQRDNIFRSVEVLIYVFDVESRELEK DMHYYQSCLEAILQNSSEAKVFCLVHKMDLVQEDQRDRIFREREEDLKRLSKPLATSIWD ETLYKAWSSIVYQLIPNVSQIEMNLSHFADIIDADEVLLFERATFLVISHCERRTHHDVH RFEKISNIIKQFKLSCSKLAAAFQSMEVKNSSFAAFIDIFSSNTYVMVITSDPSIPSAAT LINIRNARKHFEKLERME-ILSFSTRLFSVLRFESVIHEFDPYFNYRTTRFLTEEGFYNF HNWFDDRAWYPLGRIIGGTIYPGLMVTSASIYHLLHFLNITIDIRNMCVFLAPLFSSLTT LITYLLTKELKDAGAGLVAAAFISIVPGYISRSVAGSYDNEGIAIFCMLFTYAMWIKSVK TGSLFWSAICALAYFYMVSSWGGYVFLINLIPLHTLALMITGRFSHRIYVAYSTVYVLGT ILSMQISFVGFQPVQSSEHMAALGVFGLCQIFAFAEYVRSKLTRDQFQLLFKSLALIVGI TIASALGKISPWTGRFYSLLDPSYAKNNIPIIASVSEHQPTTWSSFYFDLQLLVFLFPAG LYFCFKKLTDANIFIIMYGVTSIYFAGVMVRLMLVLAPVMCILSGIAVSSILTTFMRNLD IVRKGDNNYPIKNEVATGVIIMMSLFLLTYTFHCTWVTSEAYSSPSIVLSARGGDGGRII FDDFREAYYWLRHNTPEDAKIMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMAS PEDHAYEIMRELDVDYVLVIFGGLTGYSSDDINKFLWMVRIGGSTDKGAHIKEMDYYTPQ GEFRVDREGSPTLLNCLMYKMCYYRFGSVYTEAHKPTGYDRVRNAEIGNKDFELDVLEEA YTTEHWLVRIYKVKDLQNRG-KLNIRPLMRLLLRRFFGDFTGFTSMCVNHIPPPSDNAQR KVEHIYTGPLDTDISEAMLRCDPEGPLMVHATKLFPTQDATTFHAFARVFSGTLSANAQV RVLGENYSLQDEEDSRHGQVGRLWISEARYKVQVNRVPAGNWVLIEGVDEPIMKTATITD PSATDQAHIFRPLKFNTSSVIKIAVEPVNPSELPKMLDGLRKISKSYPLITTKVEESGEH VILGTGELYLDCVMHDLRKMYSEIDIKVADPVVSFCETVVETSSLKCFAETPNKKNKITM IAEPLEKGLAEDIENQVVQISWPRKRLGEFFQTKYDWDLLAARSIWAFGPDATGPNILVD DTLPSEVDKSLLASVKDSIVQGFQWGSREGPLCDEPIRNVKLKILDAVIAEEAIHRGGGQ VIPTARRVAYSAFLMATPRLMEPYFFVEVQAPADCVSAVYTVLARRRGHVTQDAPVPGSP LYTIKAFMPAIDSFGFETDLRTHTQGQAFCLSVFHHWQIVPGDPLDKSIVIRPLEPQPAT HLAREFMIKTRRRKGLSEDVSINKFFDDPMLLELAKQDVMLS----ETFSLFDNRGDGKI YASQIGEVLRALGQNPTEAEVKKCSDPEARVSFEMFLPVYNAINKNRDNSSIEDFVEGFR VFDKEQNGTIHSAELRHLLTSLGERLTDDEVTELLQGHEGPHGDVNYEEFVKGVMNGMPE MSFNIDTGYAEGLVRGFKSGILKQTDYLNLVQCETLEDLKLHLQSTDYGHFLANEASPLT VSVIDDKLKEKMVIEFQHLRNNALEPLATFMDYITYSYMIDNIVLLITGTLHQRAISELI PKCHPLGSFEQMEAIHIAATPAELYNAVLVDTPLAPYFIDCISEQDLDEMNIEIIRNTLY KAYLEDFYQFCKDLGGATAEIMCEALAFEADRRAFIITINSFGTELSKDDRAKLYPRCGK LHPDGLASLARADDQEQVRAVAEYYAEYRVLFEESGTNPGDKTLEDKFFEHEVKLMKNAF MNQFHMGVFYGFVKLKEQECRNIIWISECVAQKHRAKIDSYIPIFSPRKAVRKISKIPFK VLDAPELQDDFYLNLVDWSSQNVLSVGLGSCVYLWSACTSQVTRLCDLSVDGDSVTSVSW NERGNLVAMGTHKGYVQIWDVSTTKKINTLEGHTARVGALAWNSDVLSSGSRDRIILQRD IRTPSVVPERRLSGHKQEVCGLKWSPDHQHLASGGNDNKLFVWNMNATTPVQTYAEHVAA VKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCVDTGSQVCNLAWSKHSNELVST HGYSQNQILVWKYPSLVQIAKLTGHTFRVLYLANSPDGESIVTGAGDETLRFWNVFSKTR STKESKSVLNMFTRIRAMLIFATYYVLSGQGYRFDIAWVLEGISPWLWANMGIGLAISLS VVGAAWGIFTTGSSILGGGVKAPRIRTKNLVSIIFCEAVAIYGIIMAIVISNSQNYFAGY AMFGAGLTVGFSNLFCGMCVGIVGSGAALADAQNPALFVKILIVEIFGSAIGLFGVIVSI LMTTKAKMID-MAATRRLGKELSDIVDESNILQWNGLIVPENPPYNKGAFRIRIDFPAEY PFKPPKITFQTRIYHPNIDEKGQVCLPIISAENWKPATKTDQVIQSLVALVNDPEPEHPL RGELAEEYTKDRKKFMKNAEEFTKKYSEKRPSDGAAESVPIQCSALRKGGYVCIKQKACK IVEMSTSKTGKHGHAKVHLVGIEIFTGKKFEDVCPSTHNMMVPNVLRKEYEVVDIDSGFF TLMTIEGETRDDLKLTVTAWSAMGDEIIKDVKIGKGKLLGPKGICVDHNGHIIVVDNKAS SVFVFQSNGKLLHKFGARGPHQFAGPHFCAINSRNDIIVSDFHNHCVKVYDEGTFITSFG ANGEGNGQFNAPTGVAVDKNDNILVADWGNSRIQVFDSSGSFLSYIHLYGPQGLDISPEG QVIVADSGNHCLKMYKYLMAAGPIAERNQDATIYVGGLDDKVSESILWELFLQAGPVVNV HMPKDRISQAHQGYGFVEFMGEEDADYAIRIMNMIKLYGKPIRVNKASAHQKNLDVGANI FIGNLDPEVDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGFAFINFASFETSDSAIEAM NGQYLCNRAISISYAFKKDSKGERHGSAAERLLAQQNPLTQVDRPHQLFADAPTPSAASG MAPPPPPPSSSQPPPIPPPMPPYGMPPPPHHPSSSMMSDSMSSSPPRPPGGGGPHGMRPP PPPPPPRGPPPPPGMRPPPPKAEPKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVRWPKY VRLQRQKATLLKRLKVPPPINQFNQTLDRQTATQMFRVLDKYRPESKQEKKARLSARAEE RVKGGADVPTKRPPVVRSGINTITCLVEQKKAQLVVIAHNVDPLEIVLFLPALCRKMGVP YCIVLGRVVRRKTATALALTHVNPEDRSSLNKLVEAVKCNYNDRVDEIKKHWGGGINSSR SQAKVAKLQKAKARELAARMRYVAAYLLAVLGGNRAPQEADIKAILSSVGIDADSANIKK VISELKGKSIEDVIAEGQSKLASVPSGGAAAAAEEKKEEESDDDMGFGLFD--IESIHAR QIFDSRGNPTVEVDLKTDKGVFRAAVPSGASTGIYEALEMRDKDPKAYHGKGVCNAVNNV NNVISPALTIDLSDQFAVDKMMLDLDGTENKSKLGANALLGVSLAACRAGAAQKGVPLYR HIADLAGNKEVILPVPALNVINGGSHAGNKLAMQEFMILPTGATSFREAMKMGSETYHHL KAVIKKKYGQDACNVGDEGGFAPNILNNEEGLELLKSAIESAGYTGKIKIGMDVAASEFC KKYDLDFKNPKSDPKSWLSSEQLFEVYQGFVDKYPVVSIEDAFDQDDWEAWTKMNAIQLV GDDLLVTNPTRVQTGIDKKACNCLLLKVNQIGSVTESIQACKMSQDEGWGVMVSHRSGET EDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELGDKAKFAGESFRNP----- -----------TNFRRFYDRGDFPIALEHDTKGNKIAWKVEIEKLDYHHYLPLFFDGLKE TEHPYDFFARQGVHDMLEHGGNKILPVIPQLIIPIKSALSTRNPKVMCTTLKILQHLVVS APAVGEALVPYYRQILPILNIFKNKNLNSGDGIDYSQQKRENVGDLINETLEAFERSGGH DAFINVKYMIPTYES--MNAQPTFETFLLFDGEKKVTIEKDTKVPNAAIFTVNKEDHTLG NALRTQLLKDPKVLFAGYKVPHPLENKFVLRIQTVAEYSPQEAFTNAITDLMAEVSLLEE NFKVAFKQ-----EDHRRKWDRSEYERLAIERKLDERKKKDPPVQREMLKPREYKVDLQS RLNKSQVITKTTPSCHQGGYYCNVCDCVVKDSINFLDHINGKKHQKNLGMSMRVERSSLD QVKQRFESNKKKADEKKKEYDFEERVRELKEEEEKHKAYKKNKRKRRAQDADLDEMDPEM AAMMGFAGFGGSKKMGCTMSAEERAALERSKAIEKNLKEDGLQAAKDIKLLLLGAGESGK STIVKQMKIIHEGGFTNEDNKQYKPVVYSNTIQSLVAIIRAMATLHIDFGDPERESDAKM VLDVIARMEDTEPFSEELLAAMKRLWADTGVQECFGRSNEYQLNDSAKYFLDDVQRLGAK DYMPTEQDILRTRVKTTGIVEVHFHFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCV AMSEYDQVLHEDETTNRMQESLKLFDSICNNKWFTDTSEEKIKKSSLTICFPEYTGKQTY EEAAQYIQAQFEAKNKSTTKEIYCHQTCATDTNNIQFVFDAVTDVIIANNLRGCGLYYHS QFVNSPMHVGNMALLPLRTKFKGPAFDIIDEALNFFKANVFFRNYEIKGEADRTLIYITL YISECLKKLQRCQSKNAGLKEMNTLALARFYLPGEAQFPLNGMYARPANRQEEDNMRAYL QQIRHETGIRVCEKVFDPATDKPSKWWMCFARRKFMDKSLSQPGQAGPYNYSYIFKYIII GDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVAGQKIKLQIWDTAGQERFRAVT RSYYRGAAGALMVYDITTRSTYNHLSSWLTDARNLTNPNTVIFLIGNKSDLEAQRDVTYE EAKQFADENGLMFLECSAKTGENVEEAFLDTAKKIYQNIQDGSLDLNAAESGVQHKPTTP RNTLSNDQPQSKDGCAC----------STPVEGTINFTQEGDVTLEGQIAGLAPGKHGFH VHEFGDNTNGCVSAGSHFNPFGKTHGGPDSEVRHVGDLGNAVAGKINITDDQVTLTGPHS VIGRTMVVHADPDDLGLGGHELSPTTGNAGGRLACGVIGITKMVNFTVDEIREHMDKKKN IRNMSVIAHVDHGKSTLTDSLVSKAGIIASAKAGETRFTDTRKDEQERCITIKSTAISLF YELPEKDLCASFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCASGVCVQTETVLRQA IAERIRPVLFMNKFDKALGTLKLSSEDLYQTFCRIVENVNVIIATYGEDGGPMGEIMVDP AKGTVGFGSGLHGWAFTLKQFAEIYATRFQIEERKLMKRLWGDQFYDSQRGFVQFILDPI YKVFEYTMPKEEALALVEKLGIKLTNEDKENYEKQLMKVVFRKWLPAGDALLQMITIHLP SPVTAQKYRMEMLYEGPHDDEAAVAIKNCDSKGPLMMYVSKMVPTSDKGRFYAFGRVFAG TVATGQKARIMGPKYVPVKSIQRTILMMGRYIESIDDVPCGNVCGLVGADQYILKTGTIT TLETAHNLKVMKFSVSPVVRVAVECKHPSDLPKLVEGLKRLSKSDPLVQCSIEESGEHIV AGAGELHLEICLKDLEEDHACIPLKISEPVVSYRETVSEESSITCLSKSPNKHNRLFFRA VPMPDGLAEDIDSGEVNTKQDGKERARYLAEKYGYDPNETRKIWCFGPEGTGPNIVVDCT KGVQYLNEIKDSVVAGFQWASKEGVLCEENLRGCRYNVLDVELHADAIHRGGGQIIPTTR RVLYAASLTASPKLMEPVYLVEIQCPEAAIGGVYSVLNKKRGVVFEENQVVGTPMFQIKA HLPVNESFGFTSTLRANTGGQAFPQCVFDHWQQLVIAAARKRKGLKEGIPPLENFYDKLM LPLSLLRTAVNHPMLVELKNGETYNGHLVSCDNWMNINMREVICTSRDGDRFWRMPECYV RGSTIKYLRIPDEIIDMVKEDNMMKHKGRVDGKGRGRGGPARGAFGRGGGPGGRGGRGGG GG-NESKLNNPPDDGISALKFGPGSSQFLLVSSWDCTVRLFDVSTNFMRMKYNHSAAVLD CCFQDNVHAYSGGLDKTLKAYDFNTNSETQVGSHDSAIRCVEYCPEVNVVVTGSWDSTVK LWDPRAPCSVGTYSQPDKVYTMAMCGDKLLVGTAGRKVLVWDLRNMGFVQQRRESSLKYQ TRCIRAFPNKQGYVLSAIEGRVAVEYLDPSAEVQKKKYAFKCHRIKEDGVEKIYPVNAIA FHSQYNTFATGGSDGYVNIWDGFNKKRLCQLHRYPSSIAALSFSHDGQMLAIASSYMYEQ DTPPDTIYIRRVSDQETKPKMDHQNRAGGKTGTGGVASSSESNRDRRERLRMLALETIDL NKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQSNLARRAAKDAKDAPSQPAPE RARVDIRKFVKIGRPGYKVTKQRDPESGQQSLLFQIDYPEIVDNIVPRHRFMAAYEQRVE PPDKKWQYLLFAAEPYETIAFKVPSREVDKDSKKFWTHWNRETKQFFLQFSFKFDPKHLR LPP---------MDDDQEIYKLWRIRKTVMQLCHDRGYLVTQDELDQTIDQFKDQFGDKP SERRPARSDLIVLVAHNDDPIDQMFVFFPDEPKVGIKTIKTYCQRMQEENISRAIIVVQA GMTPSAKQSLVDMAPKYILEQFLEAELLINITEHTLVPEHVLLTPEEKAELLTRYKLKES QLPRIQQGDPVARYFGLKRGSVVKIVRPSETAGRYITYRLVVDDKKDIGTVVGIDLGTTY SCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDVKRLI GRRWDESTVQKDIKFFPFGVINKNSKPHIKVDTGGEEKVFAPEEISAMILTKMKETAEAY LGKTVTHAVVTVPAYFNDAQRQATKDAGVIAGMTVMRIINEPTAAAIAYGLDKREGEKNI MVFDLGGGTFDVTVLTIDNGVFEVLSTNGDTHLGGEDFDQRVMDYFIKLYKKKTGKDVRK SNRAVQKLRREVEKAKRALSSTHQTRIEIESFFEGEDFSETLTRAKFEELNMDLFRSTLK PVQKVLEDSDLAKNEIHEIVLVGGSTRIPKVQQLVKDHFGGKEPSRGINPDEAVAYGAAV QAGVLSGDEDTGDLVLLDVNPLTMGIETVGGVMTKLIARNTVIPTKKSQIFSTAADNQPT VTIQVFEGERPMTKDNHLLGKFDLTGIPPAPRGVPQIEVTFEIDVNGILRVSAEDKGTGS KNEIVINNDQNRLSPEDIERMINDAEKFADEDKKTKDKVEARNELESYAYSLKNQVNDKE KLGAKLSDEEKETIETAVNEAIEWLESNQDAEAEEFQEKKKAVEEVVTPIVSKLYQGAPP P---------ADSVEDPELEAIKTRVKEMEEEAEKLREMQSEVEKQLSLEDKLDADSRSI WIGNVDYAATAEELGSHFHGCGSVNRATILCDKFSGHPKGFAYVEFVDKDSVETAQALDD SLFKGRQIKVTPKRTNRPGISSTNRPPSGRFRRGGAR-FGSGY----------------- ----VLYGTLLEISNSGSFQVLMDAVKNEKDKKARLQETILKEEQGRKRVRALQRQVVDV RREKEVEIQQRNEMIAHLKDQLQEMKAKTNMEGKYIKKCAEVGVAQTQKKCIIMEKDNRS EIESLKDKIDEENRVNAEVESYLLTHQERLQKMMEHWMEKYDKDVEAKQKELDILKASKA KDLERLQELTKMYAEYEQVVVEDRIDKEKARRKAEMEAEELKSAVRLQSWWRGTMVRKGL GPYSKKKKK-PSIGINGFGRIGRLVLRAALKAVKVVAVNDPFIDLEYMVYMFKYDSTHGR YPGEVKLVVDGQAISVFMERTPSAIPWGASGAEYVVESTGVFTTTDKAKAHLEGGAKKVI ISAPSADAPMFVMGVNQEKYEKSMNVISNASCTTNCLAPIAKVINDNFGIVEALMTTVHA FTATQKTVDGPSAKAWRDGRTAGTNIIPASTGAAKAVGKVIPDLNGKLTGMAFRVPVPDV SVVDLTCRLEKDAPYEEIKKVMKGKMKGFLGYTEDQVVSSDFITDTHSSIFDAKAGIALN PRFVKLISWYDNEYGYSNRVVDLVKYVYKQDKDDLATAILRKKSRPNRLIVEEAATDDNS VVSLSQAKMDELQLFRGDTVVLKGKHRKETVCIVLSDDAVSDEKIRINRCVRSNLRVRLG DVVSISACPDVKYGKRVHILPLDDTVEGLTGNLFEVYLKPYFLEAYRPVYKNDIFVVRGG MRAVEFKVIETDPSPYCIVAPDTMIHCEGEPVKREDEEETLNEVGYDDIGGCRKQLAQIK EMVELPLRHPQLFKSIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSK LAGESESNLRKAFEEAEKNSPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQ RAHVIVMAATNRPNSIDSALRRFGRFDREVDIGIPDATGRLEILRIHTKNMKLSDDVDLE QVAAETHGHVGADMAALCSEAALQQIREKMDLIDLEDESIDAEVLDSLAVTQENFRWALG KSNPSALRETSVEVPTVTWDDVGGLENVKKELQELVQYPVEHPDKFLKFGMTPSKGVLFY GPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFD ELDSIAKARGGNAGDGGGAADRVINQLLTEMDGMTSKKNVFIIGATNRPDIIDPAILRPG RLDQLIYIPLPDDKSRIQILKANLRKSPIAKDVDLNYLAGVTQGFSGADLTEICQRACKL AIRECIEQEIRKERERQDNPDDYDPVPEIRRDHFEEAMKFARRSVTDNDIRKYEMFAQTL QQSRGLGN-----FGSTGVFGNTPNVNPMKDIEVASPPDDSVSSMAFSPGVCPSTFLVAG SWDNNVRCWEVQQSGQTIPKAQQTHTGPVLDVAWSDDGTKVFTASCDKTAKVWDLNSNQA MQVAQHDAPIKTVHWVKAPNYSCVMTSSWDKTLKFWDTRTPNPMMTIQLPERAYCADVHY PMAVVGTAGRGVIIYQLENQPQEFRKMESPLKYQHRCISIFVDKKNSTPTGFALGSIEGR VAIHYVNTPNPKDNFTFKCHRGNVQDIYAVNGIAFHPVHGTLATVGSDGRFSFWDKDART KLKTSEQLDQPISSCAFNAQGNIFAYSSSYDWSKGHEAYDASKMKPHILLRSCFDELKPS QKKMSSPSPGKRRMDTDVVKLIESKHEVTILGGLNEFIVKFFGPQGTPYEGGVWKVRVDL PEKYPFKSPSIGFMNRIYHPNIDEVSGTVCLDVINQAWTALYDLSNIFESFLPQLLTYPN PIDPLNGDAAALYLHKPEDYKRKVSEYVRKYATEAALREQESSMSDFSEDEAQDMELMDD SDILTTLKLLIIGETGVGKSSLLLRFTDDTFDPEQSATIGVDFKVKTIQVDGNRAKLAIW DTAGQERFRTLTPSYYRGAQGCILVYDVCSQASFAKLDNWLNELETFSTKHDIVKMLVGN KIDKEPREVSREEGLKFARRYHMLFIEASAKTKEGVQCAFEELVEKILQTPGLWETDGLS IGRVIWSIINKSFCSFKIKTTTAKFCRNEHNLTGLCNRASCPLANSQYATIKEEKGVCYL YMKTIERAAFPNKLWEKVKLSRNYEKALEQISRHLIYWPRFIIHKCKQRYTRIYQYLIRI RKLSLRRKKKLVPLRRKIERREKRKEEKALVAAQLDNAIEKELLGRLKQGTYGDIYNFPE KTFSKVMDQEELSTDEESEEEIEYIAEDEVDFSDLSDLE--QSRFQAEPRIKKFTIYRWD PDTKGQKPYTQTYEVDLNNCGPMILDALIKIKNEIDPTLTFRRSCREGICGSCAMNINGG NTLACLAKIDTNTNKTSKIYPLPHMYVVKDLVPDMNNFYAQYKHIEPYLKKKDVQEEDYG KVAYFQSPEDRVKLDGMYECILCACCSTSCPSYWWNSDKYLGPAVIMQAYRWIMDSRDDF GADRLSKMNDKWSLYKCHTIMNCTKTCPKGLNPGAAVGEMKKLLVGMTSSGIPNQDIRPN HTIYINNLNEKIKKDELKKSLFAIFSQFGHIIDIVALKTLKMRGQAFVIFKDISSATNAL RSMQGFPFYDKPMRINYSKKDSDAIAKMKGTFVERPKKKKKEPVKKKKSKANTGGMPDQP PHHILFLTNLPEETTEMMLSMLFNQFPGFREVRLVPGRHDIAFVEFENEVQAGAAKDALQ GFKITPTNAMKISFAKKMDSAGRPVVICDNGTGFVKCGFAGSNFPAHIFPSLVGRPIIRS SAKVGNIEIKDLMVGDEASQLRSMLEVTYPMENGIVRSWEDMLHLYNYTFGPGKLNIEPH DCKILLTEPPMNPTRNREKMVETMFEQYGFYGLYVAIQAVLTLYAQGLMTGVVVDSGDGV THICPVYEGFALPHLTKRLDIAGRDITRYLIKLLLLHGYAFNHSADFETVRQIKEKLCYV GYDIEQEQKLALETTVLVEQYTLPDGRVIKVGGARFEAPEALFQPHLINVDGVGVAELLF NTIQSADIDTRSEFYKHIVLSGGSTMYPGLPSRLEREIKQLYLERVLKGDAEKLAKFKIR IEDPPRRKHMVFLGGSVLADIMKDKESFWMSRAEYEEQGLRVLKKLGASMSDTVGKTITC RAAVAWEAKKPLSQETIEVAPPKAGEVRIKILHTGVCHTDAYTLEGFDPEGLFPVVLGHE GAGIVESIGEGVTSVAVGDSVVPLYVPQCKECKFCKSPKTNLCSKIRATQGAGMMPDGTS RFSCKGKQLFHFMGCSTFSEYTVVAEISVCKVNPEAAKDKICLLGCGISTGYGAALNTAK VEKGSTCAVWGLGAVGLAVIMGCKKAGASRIIGVDINKDKFQCAKDFGATECINPKDHER PMQQVLVEMTDGGLDYTFECIGNVATMRAALESCHKGWGESIIIGVAAAGQEISTRPFQL VTGRVWKGTAFGGWKSRDSVPKLVEDYVSGSLNLDPFVTHHRSLDKINETFDMMHSGESM DSYDVIANQPVVIDNGSGVIKAGFAGDQVPKYHFPNYIGRPKHVRVMAGALEGDVFLGPK AEEHRGLLTIRHPMEHGIVQDWNEMERIWQYIYSKDQLQTFSEEHPVLLTEAPLNPRRNR EKAAEVFFETFNVPALFISMQAVLSLYASGRTTGVVLDSGDGVSHAVPIYEGFAMPHSIM RTDIAGRDVTRFLRLLLRKEGHNFHTSAEFEIVRTIKERACYLSTNPQKEETVDSEKQQY TLPDGSSLEIGPSRFRAPELLFRPDLIGEETEGIHEVLAFAIQKSDMDLRKTLYSNIVLS GGSTLFKGFGDRLLSEIKKIAPKDVKIKISAPQERLYSTWIGGSILASLDTFKKMWVSKR EYENEGVRAIHRKTF-----------------------------NVKRVTGLLLGSNRQG VLDVSNSFAVPFDEDDKDKNVWFLDHDYLENMYGMFKKVNAREKVVGWYHTGPKLHQNDV AINELVRKYCPNSILVIIDAKPKDLGLPTEAYIAVEEVHDDGTPTSKTFDHVPSEIGAEE AEEVGVEHLLRDIKDTTVGTLSQRITNQLMGLKGLHSKLKEIHSYLDQVSTGKLPINHQI IYQLQDVFNLLPDVHLNEFVKSLYVKTNDQMLVVYVAALIRSVIALHNLINNKIQNRDAE KNEGKEKEMGLFFSKLWGLFTNEEHKVIIVGLDNAGKTTILYQFLMNEVVHTSPTIGSNV EEVIWKNIHFIMWDIGGQESLRTSWNTYYANTEFVILVIDSTDRERLSINKEELYRMLNC EDLRKSAVLIFANKQDLKGAMTSAEISQQLNLTSIKDHPWHIQGCCALTGEGLYSGLEWI TSHLKR--IPIRRVVLNDPSAMPADYSTTPGGTLFSTTPGGTRIIYDRAFLMQCRNSPLT KSPPPNLPRIPGVTCPPPPGKRKEIYKYEAPWTVYSMNWSVRPDKRFRLALGSFVEEYNN KVQIVSLDEESSDFVARSTFEHPYPTTKIMWIPDSKGVYPDLLATSGDYLRVWRVTRIEC LLNNNKNSDFCAPLTSFDWNEVDPNLLGTSSIDTTCTVWGLETGQVVGLVSGHVKTQLIA HDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLAWNKQ DPNYLATMAMDSMEVIILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHLATAADDHQAL IWDIQQMPRAIEDPILAYTAAGEINQIQWSTTQPDWISISYNNCMEILRVRHFSLSARVA VLGASGGIGQPLSLLLKENPRVTELALYDVVNTPGVAADLSHISTKAKVTAFSGEKELKH AVKDAEIVLIPAGVPRKPGMTRDDLFNTNAGIVRDLAKVCAKICPDAMLCIITNPVNSTV PIASEVYKQEGVYNHKKIFGVTTLDVVRSNTFIAEAKGLDVNQVYCPVVGGHSGVTIVPL ISQCTPPVSFPAEEREKLTRRIQNAGTEVVEAKAGGGSATLSMAYAAARFANSLMEAMSG ESGIVECAYVFSGDADTKYFSTPLLLGPNGVAKNLGLSQINEYEHDLVKEAIPELESNVQ KGEDFIHKDIDQGKDFNIRTRTITDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFVS TLSHLRRLNSPVGRDGKLARPRQLHNTQWGMICPAETPEGSCVGLVKNLALMAYISVGSQ PSPILEFLEEWSMENLEEIAPSAIQDATKIFVNGCWVGIHRDPEQLMNTLKKLRRQMDII VSEVSMVRDISDREIRIYTDAGRICRPLLIVENQKLLLKKRHIDLLKEREYNNYGWQDLV ASGVVEYIDTLEEETIMLSMSPDQLQESG--YCSSYTHCEIHPSMILGVCASIIPFPDHN QSPRNTYQSAMGKQAMGVYITNYHVRMDTLAHVLFYPQKPLVTTRSMEYLRFRELPAGIN AIVAIASYTGYNQEDSVILNEGAVDRGFFRSVFYRSYKDSESKKGLDQEELFERPDPNHV QGMRMAVYDKLDDDGIIAPGTRVSGDDVLIGKTLTLPENEDELDAQAKRFTKRDCSVFMR RSETGIIDQVMVTINQEGYKFCKIRVRTVKTPQIGDKFASRHGQKGTCGIRYRQEDMPFT CEGITPDIIINPHAIPSRMTVGHLIECLQGKVSANKGEIGDATPFNDAVNVRKISDLLQD YGYHLRGNEVLFNGHTGRKLNAQIFIGPTYYQRLKHMVDDKIHSRARGPVQILNRQPMEG RSRDGGLRFGEMERDCQIAHGAAQFLKERLFEISDPYRVHVCNICGLIAIANLRNNTFEC RGCKNKTQISQVRMPYACKLLFQELMSMSIAPRMMIICTEQTGGFSFENCKRNHLLQKGL AAPKAYKTGTTICGVIYKDGVVLGADTRATGDTFVVDKNCSKIHYIADNIYCCGAGTAAD TEMTTQMVSSQLELHRLNTGRKSRCFTANKMLCQYLFRYQGHISAALVLGGVDVKGPHLY SVYPHGSTDGLPYVTMGSGSLAAMSVFEDGYKIDMSRDEAVQLVRDAIRAGIFNDLGSGS NVDVCVITKNVEYLRPYEVANERGKLQTEYSYKKGTTAVLTEKVKMIEMDVVMSKVTFKI TLTSDPKLPYKVLSVPEQTPFTAVLKFAAEEFKVPPATSAIITNDGIGINPAQSAGNVFL KYGQELRLIPRDRVG-MAFSFAAFCYIVALILSAFLIFFVIYHIIAFDELKTDYKNPIDQ CNSLNPLVLPEYILHLFYNVLFLFAWQWGTLILNVPLIAYHINRYLHRPVMSGPGLYDPT TIMNADELSRAQKEGWIKLAFYLLSFFYYLYSMIYELVSSMGLLTILKKMKQKEKEVRLL MLGLDNAGKTTILKKFNGEDIDTISPTLGFNIKTLEHRGFKLNVWDVGGQKSLRSYWRNY FESTDGLIWVVDSADRRRLEDTKRELESLLLEERLAGATLLVFANKQDLPGALPSKEIRA NLELDNIKSHHWLIQGCSAVTGENLLEGIDWVIDDIASRIFTMDHSKRKVCYYYDGDIGN YYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPQKAVAEEMTKFHSDDYIRFLRNIRP DNMSDYNKQMQRFNVGEDCPVFDGLYEFCQLSTGGSVAGAVKLNKQATDIAINWSGGLHH AKKSEASGFCYVNDIVLAILEMLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY GEYFPGTGDLRDIGAGKGKYYAVNFPLRDGIDDESYSSIFEPVMSKVMETYQPSAIVLQC GADSLSGDRLGCFNLSLKGHGKCVDFMKKFNLPLLLVGGGGYTIRNVARAWTFETSIALG VDIANELPYNDYFEYYGPDFKLHISPSNMANQNTPEYLDKIKIRLFENLRMLPHAPGVQM QDLPEESLNKDANADERISIRASDKGITCEEEFSDSEDEG---------------DTSTY ECNICLDTARDAVISHCGHLFCWPCLHQWLETRPNRQVCPVCKAGISKDKVIPLYGRGST DQKDPRDKVPPRPQGLRTEPENNANFPGFGFGFQ--FGIGAFPFGFFATTFNFNNGRPPP PGPGTQQHGEEQFLSKVFLWVAMMCVVWLLISMYTILNKQEHAHDDSIWSCAWARSEKDG TENIITGSVDDNVKVWKWFDLELRHTLEGHQLGVVSVDISPQGTLAASSSLDGHIRLWDI DAGKQIKTMDAGPVDAWTISFSPDSRFLATGSHTGKINLFGIESGKKESELDARGKFTLS IAYSPDGKFIACGAIDGIINIFDVTTGKSLDGHAMPIRGLCFSPDSKLLITASDDGHIKI YDVQHGNLAGTLSGHGSWVLNVAFSPDNMHFVSCSSDKTVKIWDSSTRQCVHTFYDHLDQ VWQAKYNGTGTKIVSVSEDRAIHVYDCPVADAEEFDTRYEAYFNKPDIDGWEVRKAMNDL HGMDLIPEPKILIAAMKACRRINDHSLAVRYLEAVKDKCATEEHKIWPFIMQEIQPTLKE LGISSVEEMGYDKPELALKSVYDMIVRIRGLPWSASHDEVANFLEDVNIMGGRSGIHLTY TKDGRPSGEAYIELASEEDVAKALEKDKHHMGRRYIEIYNHVDLEMEWMVKRSGPNQDAV IRLRGLPFGCSKEEVAHFFSGLEIVPNGITLMQDGQGRSTGDAFVQFASQDIAERAQQKH KEKIGHRYIEIFKSSLQELRNNYESTTGHSVHMRGLPFQAAEDDIVEFFKPLAPVNIAIH YMPGKASGQADVDFATHQEASEAMSRDRESMEHRYIELFYKDKEKPTQIRFSNITAAKAV ADAIRTSLGPRGMDKMIQSSNGDVTITNDGATILKQMQLLHPAAKMLVELSKAQDVEAGD GTTTVTVIAGSLLDAAQKLLAKGIHPTSISDSFQKAAAKSVEILETMGTPLELSDRESLL KSASTSLNSKVVSQYSNILAPLCVDAVLNVIDPATDVNVNLTDIKIVKKLGGTVEDTELI EGLLFDNKTAGSGGPSKIEKAKIGLIQFCISPPKTDMENQVVVSDYEQMDRVLREERQYI LNIVKQIKKTGCNVLLIQKSILRDAVNDLALHFLAKMKIMVIKDIEREDIEFVCKSLGCR PAASLDHFSADILGSADLVEEIHTGESKVTKVTGIANGGKTVSVLVRGSNKLVLEEADRS IHDALCVIRCLVKKRALIAGGGAPEIELSLRLSEFAHTLSGMEQYCFRAFADAMEIIPFT LAENAGLNPIATVTELRNKHAQGMKTAGINVRKGAITNILEENVVQPLLVSTSAVHLAAE TVRSILKIDDIV---MILLEIHNRVIEDILTLKFENALAKNKPETVNVTVADFDGVLYHV SNLNGDKTKVVVSISMKFFKDLQEHGADELIKREYGSYLTTVEDGYNVSLLFDENVPANY KDVVKKCGLLKRNCFASVFEKYFEFQRNNKRAVIQYRDDETMYVDARTDRVTVIFSTVFK DDDDVIIGKVFMQEFLEGRRQYQQAPQVLFSHRDPPLELQNSNARTGDNIGYITFVLFPR HDAQDNTINLIHTLRDYLHYHIKCSKAYIHSRMRAKTSDFLKVLNRAKPELKVKEKKTIM LMFCPTCANVLLVEEGPNCYRFACNTCPYIQNVNRKMSSRKYPKLKEVDDVLGGSAAWEN VDSTNEKCPKCSNDRAFFMQIQTRSADEPMTTYYKCCAMKCGHMWR------MKDEDRIF TNLYGRHDWKLKGAMSRGDWYKTKEIILKGPSWIQEEVKKSGLRGRGGAGFPTGMKWSFM NKPDDGRPKYLVVNADEGEPGTCKDREIMRHDPHKLIEGCLIAGSSMGARAAYIYIRGEF YNEASNMQAAIHEAYQAGYLGKNACGTGFDFDVYLHRGAGAYICGEETSLIESIEGKPGK PRLKPPFPADIGLFGCPTTVNNVETIAVLQTICRRGGDWFTQFGRPRNTDVMMDFDDLVR AETALGTAAIIVMNKQSDIIRCIARLIEFYKHESCGQCTPCREGVSWMNQIMGRFMTGNA KADEIDMLYEISKQIEGHSICALGDGAAWPVQGLIRHFRPTIEDRMKMFA---FTQEQVD DMNQQLNQTRSQRVRAAMFPETLEEGLQIPSTQLDPTQPTAVQRLSEPSQMLKHAVVNLI NYQDDADLATRAIPELTKLLNDEDQVVVSQAAMMVHQLSKKEASRHAIMNSPQMVSALVR AMSSTNDMETTRCAAGTLHNLSHHRQGLLAIFKSGGIPALVKLLSSSMESVLFYAITTLH NLLLHQEGSKMAVRLAGGLQKMVLLLQRNNLKFLAITTDCLQILAYGNQESKLIILASGG PAELVRIMRTYTYEKLLWTTSRVLKVLSVCPSNKPAIVEAGNGVSLSMHLGHQSQRLVQN CLWTLRNLSDAATKSDTMEGLLQMLVQLLTSSDINIVTCTAGILSNLTCNNQHNKVTVCQ VGGIEALVRTILQAGDREDITEPAVCALRHLTSRHQEAEMAQNAVRLHYGLPVLVKLLHP PSRWPLIKAVVGLIRNLALCPANHAPLREHGAIPRIVQLLIKAHQDTQRQAGVYVDGVRM EEIVEGTVGALHILAREPHNRAVIRGLNCIPLFVQLLYSPVENIQRVASGVLCELASEKE GAEMIEQEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRGE QMSADLQWMLVRKNSCFLLPGPNFSREPNNLKSRHSFYHNGLIHPRTVGVEAAPGGKGVV LVTRKANNRPAKGVSRTELKRGQRATLRAISNSLKA--YRPDLKKAAMRRASALLKSQKP VIVKKSSNEPLYCSEQIKIPPELPDILKQFTKAAIRTQPKDVLGWSAAYFRAMANHETPP VKERLELPIATQCTDTGLTPGLLKVLNNQLGPKQKVAVSVIEKKWTDLSLPIDTFHDLVR IGNFTGTVEWVKFFSLASSSLGENITDAMKMICEILTADPEGGAARISFKQFQYLYKYLA QIDGEISDEHVNTVINYLQYQVEKQDNFVQPRNFLSNDCPSLSGKLDRGQREQLMQQVQA QMAMANAQELLQKLSEKCFAKCISKPGTSLDSSEQKCIAMCMDRYMDTWNLVAKSYTQRL QKEKSRMMNRLFGTAKPKGPAPNLNDCISGIDSRGESIDKKISRLDAELGKYKDQMKKMR DGPSKNMVKQKAMRVLKQKKMYEQQRDQLSNQSFNLEQSNFAIQTVKDTKTTVDAMKVGV KEFKKEYKKINIDQIEDIQDQLEDLTEEANEIQEVLGRSYGMPEIDDAELDAELDALGDD LALDDDTSYLDEATSAPNPPTADPLA---TNKDGVPVDEFGLPQM---LTPMNPATPASP QLQNIVCTVNMACKLELKRIALHARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTG AKSEDQAKLAARKYARIVQKLGFEAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHSQFSSY EPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKVRGEIYEAFENIYPILKGFKKQ-EEEE DDFVDMGMDAEASGKHDEEDFPFQVLTADEIVKHMVDCIKEVNTVVQIPATITRILLTHF KWDKEKLMECYFTEDQDKLFSDAHVVSPFRKSFEIMCEICFLMIPTELTGLECGHRFCWQ CWREYLTTKIIDEGMGQTISCAAHGCDILVDDQTVMYLVTDPKVKLKYQQLITNSFVECN RLLRWCPRPDCGHVVKAQYYDCKPVKCKCTHIFCFACGENWHDPALCRLLRRWIKKCDDD SETSNWIAANTKECPKCHATIEKDGGCNHMVCKRCKLDFCWVCLGDWEPHGSSWYNCNRF DEEGAKKARDAQEKSRHALQRYLFYCNRYMNHMQSLKFENKLYASVRVKMEEMQHHNMSW IEVQFLKKAVDVLCQCRQTLMYTYVFAFYLHRNNQSIIFEENQKDLENATEQLSEYLERD ITSDMLVDIKQKVQDKYRYCESRRKVLLDHVHEGYEKELWEYQDMATNDGKPSTTERAVK SVPFPPSHRLTMNEVYDPNGKPRPDVLKQHFILEGRVEETVALKIIREGAAILRQERTII DIDAPVTVCGDIHGQFYDLMKLFEVGGSPATTRYLFLGDYVDRGYFSITECVYDACMEAF DCLPLAAIMNQQFLCVHGGLSPEIHNLDDIRKLDRFKEPPAFGPMCDLLWSDPLEDFGNE KTAEHFTHNSVRGCSYFYSYAACCEFLHRNNLLSIIRAHEAQDAGYRMYRKSQATGFPSL ITIFSAPNYLDVYNNKAAILKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVT EMLVNVLNICSDDELMSEQDDTFEGAMAARKEIIRNKIRAIGKMARVFTVLREESESVLQ LKGLTPNGLLPIGALSGGKETLQGAMSGYSPTHKISGFDEAKYLDKLNERMPPRKAAYTP RGDRGGFSGGRGGGGRGGFSGGRGGGRG--GGMRGGKSVFVEPHRHKGVFIARGKEDALA TKNMVPGDSVYGEKRISVEEGNKIEYRAWNPFRSKLGAAILGGVANIHMEPGSKVLYLGA ASGTTVSHVSDIVGPEGLVYAVEFSHRSGRDLLNVAKKRTNIIPIIEDARHPHKYRMLVG MVDTIFADVAQPDQARIVAINAHNFLKNAGHIVISIKANCIDSTAEAEAVFAGEVNKLRS EKIKPREQLTLEPYERDHAVVVGQYRPPPK-MDPKKLSEMMGRIQKGGKGAGLGLGFLAA AGSVAYGLYQSMYTVDGGHRAIIFSRIGGIQPDIYREGLHLRVPWFQYPIIYDIRARPTN LASPTGSKDLQMVNINLRVLSRPDSAMLPTIYRQLGTNFDERVLPSICNEVLKSIVAKFN ASQLITQRQQVSLMIRKELTERAKDFNIILDDVSITELAFGREYTQAVESKQVAQQEAQR AQFVVEKAKQERQQKVVQAEGESAAAQMIGEALNANPGYLKLRKIRAAQNISRTIAASKN RVYLNAGTLMLNLTDEEFDSASESYTDSSSEEDDVNPRDKDQKNSKGFTDFCVRVEQAAF GRREIEIAEQEMPGLIALRKRAQGDKPLNGARIVGCTHITAQTAVLIETLGALGAKLRWS ACNIYSTQNEVAAALAEAGYSIYAWKGETEDDFWWSIDRCIHSENWQPNMILDDGGDATH LMLKKYPTIFNMVKGIVEESVTGVHRLYQLSKTGRLTVPAMNVNDSVTKTKFDNLYSCRE SILDALKRTTDVMFGGKQVVVCGYGEVGKGCAEALKGMGAVCMITEIDPICALQACMDGF RVVKLNEVVRNVDIIITCTGNKNVVTREHMDKMRNGCIVCNMGHSNTEIDVNSLRTADLT WERVRSQVDHIMWPDGKRLILLAEGRLVNLSCSSIPSFVVSITAATQALALIELFNAPGG RYKQDVYLLPKKMDEYVASLHLPSFDAHLTELSDEQAKYLGLNKAGPFKPNYYRYPDPDA IKMFVGQIPRSMDESDLRKMFEEFGPVFQLNVLRDKVTGQSKGCCFVTFYTRKSALEAQN QLHNIKTMAGMQHPIQMKPADCEKRN-EERKLFVGMLSKKCNENEVRMMFAPFGTIEECT VLREQNGQSRGCAFVTYASKQCAQNAIKGMHHSQTMEGCRFPLVVRFADTQKEKEMKKLQ QMQSALQIQFIGGVAGGTASVYVGQPLDTVKVKMQTFPTMYKNAFTCFTSTFRKEGARGL YAGTTPSLENAILFMAYGMCQKAVMCAAFFSSLTLCPTELIKCKQQALTKQILREEGIRG MFRGLVPTFAREMPGYFFFFGGYEASRSLLTPAGKDKDDLESKTALCGGIGGATLWILVF PTDVIKSRIQVRNEGFLALYKGLGPTLLRTFPATGALFLAYENSTKILNGGANEFTRLSQ SVSNNIQKITQNVAQLQKLVNQIGTQQDNADLRDRLHQVQHYTNQLAKDTKNYLTELSHL QSDQKQRRIQKDRLMNDFTTSLNNFQAVQRKTAEKERESLEDVDLELMRERDQSVRKLES DIMDVNQIFKDLGMLVHEQGEVIDSIEANVESVHVEDGTEQLRQARDYQSKARRKKCILL LILLIILIIIAVIIAVTV-MVNVMKGILIECDPAMKQFLLHLDETNALGRSFVIQDLDET HIFISADILETLTSKIDDLMDKLHF--GKKGEKAPTSQEAIQRLRETEDMLSKKSDYLEK KIESEIATARKRAALQALKRKKRYEKQLQQIDGTLSTIEFQRDALENASTNTEVLRVMGD AAKALKAAHKNMDVDDVHNLMDDVAEQQEIANEISEAISNPVGFGQDVDEDDLMAELEDL EQESLDEQLLDV-NLPSVPQTEDDDMRELEAWASSMSKFHNRVRQILMASGSTTFTKIVN KWNTALIGLMTYFREAVVNTQELLDLLVKCENKIQTRIKIGLNSKMPSRFPPVVFYTPKE LGGLGMLSMGHVLIPQSDLRWSKQTDMGITHFRSGMSHDDDQLIPNLYRYIMPWESEFID SQRVWAEYALRTDMIQALGGVEGILEHTLFKGTYFPTWEGLFWEKASGFEESMKYKKLTN ASKDTMDNTTTQKYWLDIQLRWGDYDSHDVERYARAKFLDYTTDNMSIYPSPTGLLMAID LAYNLHSAFGNWFPGCKPLIQQAMAKIMKANPALYVLRERIRKALQLYSSEPTEPYLSSQ NYGELFSNQIIWFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSV WAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKG SELQLPFQACLKVEKFGDLILKATEPQMVLFNLYDDWLKTISSYTAFSRLILILRALHVN NDRTKMILKPDKTTITEAHHIWPTLSDDEWIKTEVQLKDLILADYGKKNNVNVASLTQSE IRDIILGMEISAPSAQRQQIAEIEKQTKEQSQLTATTTRTTNKHGDEIITSTTSNYETAT FSSKTEWRVRAISATNLHLRTNHIYVSSDDIKETGYTYILPKNVLKKFITISDLRAQIAG YLYGVSPPDNPQVKEIRCIVMPPQWGTHQTVHLPIPLPSHEYLEEMEPLGWIHTQPNELP QLSPQDITTHAKVMGEHPTWDGEKTIVITCSFTPGSCSLTAYKLTPSGFEWGRQNKDSGN NPKGYLPSHYEKVQMLLSDRFLGFFMTPQQTSWNYNFMGVRHDPNKKYELTLANPKEFYH ENHRPSHFLNFSSLEDGADREDLF--YHNSRPNLKINKDTRVICQGFTGRQGTVHSQQAI EYGTKMVGGVSPAKAGQTHLGLPVFASVKDAKEATGADASVIYVPPRFAAAAIEEAIDAE IGLVVVITEGIPQQDMVRVKYKLLRQDKTRMIGPNCPGIIQPGGCKIGIMPGHIHKPGKI GIVSRSGTLTYEAVHQTSLVGLGQTVCVGIGGDPFNGTNFIDCLDVFLKDPETEGIVLIG EIGGQAEERAADFLKEHNGPNAKPVVSFIAGLTAPPGRRMGHAGAIISGGKGGAQEKIAA LENAGVLVTRSPAQMGSTMLKAMQDAGKPGAEALKCTLCNERLEDTHFVQCPSVSEHKFC FPCSRDSIKRQGAGAEVYCPSGKKCPLVGSSVPWAFMQGEIATIIGFNKYVQIGRVALVA YGPDQGNLVVIIDVIDQNRALVDGPCTGVKRQALQFKRMHLTKFVIVPRSARTCIIKKKW EKSGITEKWQETSWSKRLNDEKLKKNMNDFDRFKLMKAKQTRNRIINMEFGRLKNLAKQS CPLLLRVFCNNSRHHPMSEYARGQTPANELQIYTWMDASLKELTNLVKEVNADARRKGTF FDFSVVFPDARSPQYRMREIGSTCAGRKGSDDAKTLAGTKFKIGDYLDIAISPP-GLGKT LQTISLLGYMKHYRNIPSPHLIIAPKSTLMNWMAELERWCPTLRSICLIGDQEKRAAMIR DEILPGEWDVCVSSYEMVIKEKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKSASR LLLTGTPLQNNLHELWALLNFLLPDVFNSADDFDSWFNTSNCFENDDLVTRLHAVLRPFL LRRIKADVEKRLLPKKETKVYIGLSKMQREWYTKILMKDIDVVNGAGKSDKMRLLNILMQ LRKCCNHPYLFDGAEPGPPYTTDQHLVDNCGKMVLLDKLLPKLQEQDSRVLIFSQMTRIL DILEDYCYWKNYNYCRLDGQTAHEDRQKSINEFNAPNSTKFVFMLSTRAGGLGINLATAD VVVLFDSDWNPQVDLQAMDRAHRIGQKKQVRVFRFLTENTVEERIVERAEMKLRLDSVVI QQGRLQDSNASKEVLQMIRHGANHVFSSKESMITDEDIDALLERGEAKTKEMEKKLEELG ESSLRTFTLETPD-SVYQFEGKDYREKQDIPGVGHWIEPPKRERKANYAVDAYFREALRV SEPKAPKAPRPPKQPNVQDFQFYPPRLFELLDQEIYLYRKSIGYRVPKNPDLGSDAERVR KEEQVKIDEAEALNEDELAEKEELLKRIQQL-------------KYGRDDIESISKDVEG KTPEEVVEYSFVFWERCNELQDIERIMAQIERGETKIQRRISIKKALDAKMSRYRAPFHQ LRLQYGTNKGKNYTEEEDRFLVCMLHKLGFDRENVYDELRTSVRQAPQFRFDWFIKSRTA VELQRRCNTLITLIERENMELEEREKAEKKKDANPSWADQVEDGDD-VLPPPTEDFHAST GTKILTEYKFNDDDKKVKVVRTFKIEKRKVSKSIATRKAWKKFGAAEKDAPGPNPSNTIE DVIIQFVHSKDSNDEDPLNKIKVSCRICKGDHWTTKCPYKDSLAPLQESLAPGGKYVPPN LRDGGNRRGESMMGDESATIRVTNLSEDTREADLQELFKPFGNISRIYLAKDKVTGQSKG FAFINFHRREDAARAIQGISGFGYDHLILNVEWAKPSMSETYDYLFKFLVIGSAGTGKSC ILHQFIESKFKQDSNHTIGVEFGSKVVNVGGKSVKLQIWDTAGQERFRSVTRSYYRGAAG ALLVYDITSRESYNALTNWLTDARTLASPNIVIILVGNKKDLESEREVTFLEASRFAQEN ELMFLETSALTGENVEETFLRCARSILTKIESGELDPERMGSGIQFGDASLRRL------ ---MIQPSEKQKLETSQWPLLLKNFDKLNVRSSHYTPIPAGCSPLKRPIKDYITTGFINL DKPSNPSSHEVVAWIKRILRVEKTGHSGTLDPKVTGCLIVCIDKATRLVKSQQSAGKEYV CIFRLHSAVEDVKKIYSAVETLQGALFQRPPLISAVKRQLRVRTIYESKMLEYDENKNQG IVWVSCQAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGVLSEKDAMSTMHDVMDAQWLYD HHQDEAYLRRVISPLEALLVSHKRIIMKDSAINAVCYGAKVMLPGVLRYDDGIEIDDEIV IVTTKGEAVAIAVAQMTSAVIATCDHGQVAKLKRVIMERDTYPRKWGLGPVASRKKQMIK DGKLDKYGRKNESTPSDWLSAYTDYKAIKAKVKQEPSTEKKKKKKKKKMAEVGWDRKRTP KATEKRSQQAVNAAQRSGMEVETSKKFSAGQNKQHSSNANTARLDRETEELKHSHVGLDT ARLIQQGRQAKNLTQKELATKINEKPQVVNDYEAGKAIPNNQVMSKLERTLGLKLRGKDR GKPLAPKMLKPKALTQILSQTNTGGVQSTLLLNNEGALLAFSGYGDKDARVTAAIASNIW SAFEKNGKAAFNEDELQLVLMDCEDGKVAITRVANLLLCIYAKENVGLGMLRAKAKALAE YLHEPLTHVASSTGATLRIPSKQQTLDDAYAVPANFLEIDVVNPEGKKRYTDYEVRMRTN LPVFKIKESSVRRRYSDFDWLRGELDRDSKIVVPPLPGKAWSRQLPFRGDEGIYDDEFIE DRRKGLESFVNKVAGHPLAQNERCLHMFLVEPVIDKNYVPGKVRASRQYSARLEEVGVLE QPKLQGKYETGQIFLHRVFGYRGVVLFPWVGKVFDRDIAAKSNKEVKGRTHTYYQVLVDM RDLPHIRVGAESVTFLSNPESGTIYSIPGLDYAGHEDILPYKTTEKQPIQNYLFDKFLTT SDGFLARDTLREWQDKNHPWLELTDVHRETTENMRVTVMPFFIGEVQQTHVYWWRYCIRL ENLGDETVQLRERHWRIFSLSGTLETVRGRGIVGKEPQFTKANPAFQYTSHVSLQAPSGH MWGTFKMERPDGSTFECRIPPFSLESKHEDGMATSKGANTYNRQNWEDSDFPTLCQTCLG DNPYIRMMKDKYGMECKVCERPFTVFRWCPGARMRFKKTEVCQTCAKLRNICQTCLLDLE YGLPTQVRDAALKVHESMPKSDVNKEFYTQNMEREIANSDGTTAVGPYGKSQNSHEMLMK LARTAPYYKRNRPHVCSFWVKGECKRGEECPYRHEKPTDPDDPLSDQNIRDRYYGINDPV AEKLMSRYSTLPKLEPPEDQDVFLMIRYKKTSIFMDAKETTSVLELKKMVQGITKRDLED IRLYKDNKTLGDCGFTSSTARAQAPATIGLAFREFEPLEIAALSTPPELPDVMRPQESSA SQQQEHLMRYDATLLRNRFDVNAVIDPIVATQVLEEGMEELRRKDHPLPFKFPNSPGGCA YGREPFLPDAIFDMWHPLEKAQYPEYFARREQRKQEYVDRWEKKYGGSEMEDYIKVEKIG EGTYGVVYKGRNKKTNRTVALKKIRLESEEEGVPSTAIREISLLRELQHPNIVCLEDVLM QEKKLYLVFEFLSMDLKKYMDSIPSDQTMTPMLVKSYTYQILQGICFCHGTRVLHRDLKP QNLLIDSNGVIKLADFGLARAFGVPIRVYTHEVVTLWYRAPEVLLGSQRYSTPVDIWSIG CIFAEMVKKRPLFHGDSEIDQLFRIFRTLTTPTEETWPGVTSLPDYKPTFPNWKTNTLAQ SVNADGLDLLQKTLTYDTTTRISAKEALNHPYFAARAFNRLIWLGAGIAGAAGVVNTALY NVDGGKRAVIFDRFAGVKDIVTGEGTHFLIPWVQRPIIFDIRSRPRSVPTITGSKDLQNV NITLRILFRPLTERLPQMYTNIGVDYDERVLPSIVNEVLKAVVAQFDASELITQREFVSQ KITDELTRRSAQFGIILDDISITHLTFGREFTAAVEMKQVAQQEAEKARYVVEREEQRKK AAVIRAEGDTKAADMLAKSFAQAGEGLVELRKIEAAEDIAYQLSQSANVVYLPSQQGTLL NL-MKVIQTNQKVTIPKGIDVKVKSRTVTVKGPRGTLSRNFSHLSLDIRMLKKNELIVEK WFGIKKELAAVRTVCSHIENMIKGVIRGYRYKMRSVYAHFPINIAIAEDKKHVEVRNFLG EKYTRHVKMLGDVVIEASSTTKDEFILEGNDIELVSRSGALIQQSTTVKDKDIRKFLDGV YVSHKGHVVEEMGCAVSNDDKAAQERSKAIDKGLRADGEKASREVKLLLLGAGESGKSTI VKQMKIIHEKGYSSEECLQYKPVVYSNTIQSMIAIIRSMGQLKIDFGHPDRAEDARQLFA LAGNAEEGDLTQDLAAIMKRLWKDSGVQECFSRSREYQLNDSAEYYLNALDRISQQGYVP TEQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFIVGMSE YDLTLAEDQEMNRMMESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICFPE FTGSNTYEEAAAYIQMQFNKRKDTKEIYTHFTCATDTNNVQFVFDAVTDVIIKNNLKDCG LF-KYAEMKRMISKTDGRIKKSERISKKPRKAKPEQLKIHEVPQASSAMFFQFNTQLGPP YHVLVDTNFINFSIRNKLDMVQSMMDCLYAKCIPYITDCVMAEIEKLGRRYRVALRIAKD ERFQRLPCLHKGTYADDCLVQRVTQHKCYIVATCDKDLRRRIRKIPGVPIMFLSQHKYSI ERMPDAFGAPKMSFSSDEVNFLVYRYLQESGFSHSAYTFGIESHISQSNINGALVPPAAL LSIIQKGLQYTEAEISIGEDGAERVIESLSLIDAVMPDVVESRKQAATKAGGG--GAEAM EIDGSIEIPSNKATVLRGHESEVFICAWNPKNDLLASGSGDSTARIWNMNDSSNANQLVL RHCIQKGGTEVPSNKDVTSLDWNCDGTLLATGSYDGFARIWSTDGGLVSTLGQHKGPIFA LKWNKKGNYILSAGVDKTTIIWDASSGHCTQQFAFHSAPALDVDWQSNTSFACCSTDQCI HVCKLMVDKPIKTFQGHTNEVNAIKWDPQGNLLASCSDDMTLKIWSMKQDTCVHDLQAHS KEIYTIKWSPTGPSTNNPNAPLILASASFDSTVRLWDVERGSCIHTLTRHNEPVYSVAFS PDGKYLASGSFDKCVHIWNVQSGSLVHSYRGTGGIFEVCWNHRGDKVGASASDGSVFVLD LRKSNNDLASLFECPVCFDYALPPIMQCHSGHIVCSHCRDKLTQCPTCRGPLGNIRNLAM EKVASQVMFPCKYCSSGCPVALPHTDKTEHEDTCEYRPYCCPCPGASCKWQGSLEQVMTH LMQQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFEHHFMLVLEKQEKYEGSQLFYA IVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHDGVQSAINSSDCLVFDTNIAQLF ADNGNLGINVTINRCMAYQTFQQEYMQMPAITRAYTTSCVLTTLAVQLEILTPFQLYFNP ELIFKQFQIWRLLTNFMFFGNIGFNFFFNMIFTYRYCRMLEEGSFRGRTADFLLMFIFGG SIMTAIVNQVFLGQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPYLPWVLLGFSLLLGNS IMVDLMGIAVGHFYFYLEDVFPLQPGGFRMLKTPAFLKWLCNPVHEDPAYNPLPPGGFDW GGGMELLSDQGFRVDGRKPNELRRIQCRMGVFSQADGSAYIEQGNTKVLAAVYGPHEVRG SKSKHDQALINCQYSMAVFSTGERRRRPRGDKKSVEMTLHLKQTFEAAILTHLYPRSQID IFIEV-------------------------------------IKDTALLDINYLEESSGA ELAAAALPKWDQIVLL-------ENHLNQVLDTAVKGCKDVYAILDAAVREMSGTYYFTV VGHNDNPVFEMEFVPPNKVNDPKKDDHRHLNQFIAHAALDLVDEQMWTTSNMYLKIVDKF NEWFVSAFVTAKRMRFIMLHDAKNEDGIKNFFQEVFETYIKYAMNPFYEENTPIRSQAFD KKIQVYGRKYL--QYRLAHTDLQVPDFDYYRKAPKENNRKAFTYLMLAGAGAPALYGTKT VITQFVSSMSASADVLALAKIEINLDEIPEGKNVTFKWRGKPLFVRHRTAEEVDKEAAVD VGSLRDPQHDTDRVKNPEWLIILGVCTHLGCVPMANAGDYGGYYCPCHGSHYDASGRIRA GPAPLNLEVPYYEFVEDNLLVVGMSRQTTRAVDPRKVSGELFTLTYGSLVAQLLKDYEND DEVNKQLDKMGYNIGVRLIEDFLARSNVGRCQDFRETADVIAKVGFKMYLGLTPVVANWS PAGDEFSLLIENNPLIDFVELPEGHSHLNFSNILCGALRGALEMVQMDVAVWFVQDQLKG DNLTELRLRFIKRLEDAVPAGEDENVKAFLAAAKDDFNKKWDEPAQNTASLDEFDRIKTL GTGSFGRVMLVQHKATKQHYAMKILDKQKVVKLKQVEHTLNEKKILQAISFPFLVSLEYS FKDNSNLYMVLEFVTGGEMFSHLRRIGRFSEPHSRFYAAQIVLVLEYLHHLDIMYRDLKP ENLLIDEVGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVY EMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNAVN DIKTHKWFQTTDWIAIYQKKVEAPFIPKCKGPGDPSNFDDYEEEPLRISSTEKCAKEFAD FMLADTLLILSISIATAFLGEGLTWLLVYRTEKYKKLKTEVEKQSKKLEKKKEASGDASG RNAKKKIERQEERLKNNNRDLSMVKMKSMFAIGIVFTALLSMFSSIFDGRVVAKLPFVPI SWLQGISHRNLMGSDFTDCSFIFLYILCTMSIRQNIQKLLGFAPSRSASKQGGGLFSTCM KHFDSWTDEEQVQFVEYLISRMCHHQHGQVNTYLKPMLQRDFISALPAKGLDHIAENILS YLDAESLKSAEQVCREWYRVISDGMLWKKLIERMVITDNLWKGLAERRGWGQYLFRPKPG EQPKDNKFYRNLYPQIISDIDRIENNWRTGRHELKRIHCRSETSKGVYCLQYDDNRIVSG LRDNTIKIWDRNSLDCVQVLTGHTGSVLCLQYDENIIISGSSDSTVRVWSLKTGEMLNTL IHHCEAVLHFRFADGMMVTCSKDRSIAVWDVQSPTDINLRRVLVGHRAAVNVVDFDQKYI VSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYHDRLVVSGSSDNTIRLWDIECGACL RVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLAAALDPRAPAGTLCLRTLVEHSGRVF RLQFDEFQIVSSSHDDTILLWDFLNMAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNS TFISTIGIDFKIRTIELEGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKS FYNIRTWIRNIEEHASNDVEKMILGNKCDMNDRRQVSKEKGEALAVEYGVKFLETSAKAS INVEEGFISLARDIKAKMDRKLADGETSADRNVEIWKIKKLIKSLEAARGNGTSMISLII PPKDQISRVAKMLADEFGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVIYCGT IVTDEGKEKKVNIDFEPFRPINTSLYLCDNKFHTEALTALLADDNKFGFIVMDGNGALFG TLSGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAEVAVQLFISNDRP NVAGLVLAGSADFKTELSQSDMFDPRLQGKVLKIVDVSYGGENGFNQAIELAAEALSNVK FIQEKRLIGKYFDEISQDTGKYCFGVDDTLKALEMGAVEILIVWENLDIIRYTLKNHQND DEKILFLKPEQEKDKTYFTDKETGVELELVESMPLLEWFANNYKTFGATLEIITDRSQEG AQFVKGFGGIGGILRYQVDFQGMEPLDDL-DDYDLDDYITRSSQPLVGKRNKEDEKYIQL IMDANAQSHKLFIMDARPSVNAIANKAKGGGYESEDAYQNAEIVFLDIHNIHVMRESLRK LKDICFPTIDDSHWLSNIESTHWLEHIKQILSGAVRIADKVESNKTSVLVHCSDGWDRTA QLTALAMLMLDPYYRTIIGFEVLIEKEWLSFGHKFAQRIGHGEDKHSDADRSPVFLQFID CVWQMTRQFPNAFEFNEHFLVTILDHLYSCLFGTFLFNTEQQRSKEKLKHRTVSLWSYIN CQTEDYTNPLYQHVLFPVASMRRIELWTGYYLRWNPRMRPQEPIHLRNRELLLLKAQLQR RVDDLQREQEVRSSPFKPFIPHLPFDLVQCETAFPRAKPPQDDKAFSDSLLKRAQELAPT PQEQTAVLNLVTKINTVLDNLVVAPGSFESAQLEEVRQVGSFKKGTMMAGHNVADIVVIL KTLPTVEAVQALANKVIEELRISDPREVLSMLTNESGFEISSSEATVKALVTTIPPNLKK LDSDLHLDGKIMQGHLAAVRHSRWFEENAFHSGIKVLIRLIRDLRNRFEGFEPLTPWIID LIAHYSILNNPSRQPLLIHIAFRRFLQLLAAGFFIPGSAGIVDPCEQGNVRIHTVMTLEQ QDQVCCCAQTLLRVLSHGGYREILGLQGNPRIATEMSVWEGVVVTPSDKAYEK---VVRL IQQYLKESNLLRTLTVLQEETGISLNTVDSVDTFISDINNGHWDTVLMAIQSLKLPDQKL IDLYEQIVLELVELRELGAARSLLRQTDPMMMMKQHYPDRYVHLETMLARSYFDPREAYP EGQTKERRRAAIAHALAGEVNVVPPSRLLALLGQALKWQQHQGLLPPGTSIDVFRGKAAV REQEDEKYPTQLSKHIKFGQKAHVECAKFSPDGQYLVTGSVDGFIEVWNFTTGKVRKDLK YQAQDNFMMMDDAVLCMCFSRDSEMLASGGQDGKMKVWKIQTGQCLRKFERAHSKGITSI SFSKDNSQILSASFDQTIRIHGLKSGKTLKEFRGHTSFVNDAIFAADSHHIISASSDGSI KIWNIKSTDCQSTFKSFGGTAGVDITVHSIHQLPRNVEQFVVCNRSNTVSIMNMQGQIVR SFSSGKREGGDFVCCTISPRGEWVYCVGEDLTLYCFSISSGKLERTLQVHEKEVIGISHH PHQNLIATYSEDGLLKMWKP----------------PRAARMWEVARVEMMPPGEIAAAK KSMGVIWHMWTAGYKNLTVKEASIVCAEIAVWFFLGEMIGRRHIIGYNIPGTTHF---HI PKFYYKLPSDEEFILLKLREESRAVFLQRRSRELLDNDELQGLWLLLDKHHTAPSVGEEQ MINYEDFLKVASEAGAKCRPFFTASVFAKLLQTDPYGRISIMQFFNYVMRKVWLQQTRIG LSLYDVAGLGFLKESDLENYILELIPTLPQLDGLEKSFYSFYVCTAVRKFFFFLDPLRTG KVKIQDILACSFLDDLLELRDEDLPKDLQESNWFSAPSALRVYGQYLNLDKDHNGMLSKE ELARYGTGTLTEAFLDRVFQECLTYDGEMDYKTYLDFVLALENRKEPQALQHLFRLLDVQ NKGFLNIFDLNFFFRAIQEQMKLHGQDPVSFDDVKNEIFDMVKPDDPLCITLQDLLRCGQ GDVVVSILIDLNSFWSYENRE-EMVRGQPFEVGPCYANLAYIGEGAYGMVVSAYDTKHKT KVAIKKISPFEHQTYCQRTLREIKILTRFRHENIINIQDIIRANSIAEMKDVYIVQCLME TDMYKLLKTQKLSNDHVCYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFG LARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYSKAIDVWSVGCILAEMLSNRPIFP GKHYLDQLNHILGVLGSPGSEDLNCIINDKARGYLQSLPFKPKVPWSTLADPKALDLLDK MLTFNPHRRITVEECLAHAYLEQYYDPQDEPVAEEPFTFETELDDLPKERLKELIFQETV LLRDRELSPPKTTPEWVKFCKQLFGGFSMLLWLGAILCFIAYSIQASTYEDPAGDNLYLG IVLTAVVVVTGIFAYYQEAKSSKIMESFKNLVPQFALVIRNGEKLNLHAEELVVGDIIEV KFGDRVPADVRVISAHGFKVDNSSLTGESEPQSRSSDFTHENPLETRNLAFFSTNAVEGT MRGIVVSTGDRTVMGRIANLASGLEVGETPIAREIGHFIHIITGVAVFLGVTFFIIAFIL GYYWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTI CSDKTGTLTQNRMTVAHMWFDNRIVEADTSEDQTSATYDGESVTWMALARICMLCNRAEF KSGQENIPVLKRECNGDASESALLKCVELSIGHVCEFREKNRKVIEIPFNSSNKYQVSVH EGDDRYILVMKGAPERILDRCSTILINGEERALDEEWRDAFNQSYLELGGLGERVLGFCD YFLPLDQFPVGYPFDADEENFPLTGLRFVGLLSMIDPPRAAVPDAVGKCRSAGIKVIMVT GDHPITAKAIAKGVGIISEGNETVEDIAARLGVPVSEVNPRDAHAVVVHGSDLRDMTPAQ IDDILANHSEIVFARTSPQQKLIIVEGCQRQGQIVAVTGDGVNDSPALKKADIGVAMGIA GSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLIFILAD VPLPLGTITILCIDLGTDLVPAISLAYERAESDIMKRMPRDPLNDKLVNSRLIGMAYGQI GMIQASAGFFVYFVIMAENGFWPSRLLGLRKAWDSKGVNDLEDSHGQEWTYAQRKVLEYT CHTAFFMSIVIVQWADLMICKTRRNSIIHQGMTNHHLTFGLFFETALAAFMAYCPGLDKG LRMYPLRWTWWIVPMPFSLVIFIYDEGRKYLLRKNPGGWVETETYYSFKKLSTGKKVGLG LTAGAVSVGAALQDLILHPPHLPWSHSGVLDSLDHASIRRGYYVYKQVCAACHSMDFIAY RELVGVIFDEDEAKAEAAEVMVKDGPDEEGKMFERPGKLSDRFPNPYENEEAAKAANNGA LPPDLTYIVKARHGGEDYIFSLLTGYCDPPAGVDIKEGTYFNPYFLGGAISMAQALYNEI IEYEDGTPATQSQLAKDVCTFLKWTSEPEHDIRKRYAIKFFALMITPLAFWYKRFKWSVV KSRKIVWTRPDLPSACTYKPG-MKDSPHAHKQRLPKVFPNILGKIGESPLVAINKIAENS GLECNFFGKCEFFNAGGSVKDRIALRMVEDAEAKGQLKPGDVLIEPTSGNTGIGLALTAA VKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTSASFDSAESHIGVAHRLLHEIPNAHI LDQYRNPSNPLAHYDGTAVEILDSLDDKVDMVVCGAGTGGTITGIARKIKEKCPNCKIVG VDPFGSILAEPADVDYYEVEGIGYDFIPTVCDREFIDKWYKCSDKPAFQMSRRLIKEEGL LCGGSSGGAMYIAMQAAKDLGMKKGDNVVVVLPDSIRNYMTKFLSDEWMQEREFMSDIGS EEKDGQYLGEYEGERNERDERHGHGKARLPNGDTYEGMYENNKRHGHGTYRFKNGAQYDG EWMKNKKHGSGNFIYPDGSKYEGNWVDDQRSGTGKYFYVNGDIYDGEWQRHVRHGQGTYY YKETGTRYVGTWKEGKRQGHGELIHANHKYVGPFKDDRPEGKGKYVFDIGCQQHGEYIMP DIMRLITKDLSEPYSIYTYRYFIHNWPKLCFLAKSKGECIGAIVCKLDLHKKMVRRGYIA MLAIDQNYRRKGIGSQLVLMAIKAMIADECDEVVLETEISNKSALNLYQNLGFVRDKRLF RYYLNGVDALRLKLWLRELDALMFHLSPNQRKCLKDEIHKGVLVTGEYDISEGPGQTANV LVTDSKGHIFFTREDADQGKFAFTTEEYDMFEVCFETKMQRGVGGVDREIFLSMKHGIEA KSYEEIAKAEKLKPLELELKKLEDLSESIVNDFAYMRAREEEMRDTNESTHSRVLYFSVF SMCCLLGLATWQVLYLRKYFKSKKLIEEMESGRTSSVGNDILGFLGQVVNKPEHGHLDWV KICEQSSKVITFIDLAGHEKYLKTTVFGMTGHAPDFSMLMVGANAGIIGMAKEHLGLALA LSVPVFVVVTKIDMCPPNVLQETLKLLQRLLKSQGCRKIPVLISTVDDVIVSATNFTSER MCPIFQVSNVTGENLDLLKMFMNLLSTRIEKEPPEFQIDDTFSVPGVGTVVSGTCLQGII HINDTLLLGPDTLGQFQPIVVKSIHRKRMPVTEVRGGQTASFALKKSYIRKGMVMVSPKL NPKACWEFEGEILVLHHPTTMSVKYQAMVHVGSVRQTATIIKMSKELLRTGDKAIVLFRF IKNPEYLRKDVRMVFREGRTKAVGTVVHLFPHVSLNTRQQRAAKKAVEQEKLSQTDDHHF YLFKVLRAHILPLTNVAFNKSGSSFITGSYDRTCKVWDTSSGEEMHTLEGHRNVVYAIAF NNPYGDKIATGSFDKTCKLWSAETGKCYHTFRGHAAEIVCLAFNPQSMIATGSMDTSAKL WDIVCSLNGHSAEIISLAFNTTGDKLITGSFDHTVSVWHQRLHTLIGHKAEISSAQFNWD CSLIATGSMDKKCKIWDAHTGQCVGTLSGHDDEVLDVTFDFTGKYLLTASADRVYNVTTH SKLEGHEGEISKITFNPQGTRVLTASSDKTARVWDHETGECKQVLEGHTDEIFSCAFNYE GTTMITGSKDNTCRIWRGDVFMEKHWRSVIHRSICDYFFEAQGKAATPDDVPPIISTPHH YLINIYRNQLYLVAVVMTEVPPLFVTEFLHRVMDTFEDYFTDCTESAIKDNYVIVYELLD EMLDNGFPLATESNILKELIKPPNLLRTITDTVTGKSTSVSEILPTGQLSNVPWRRTGVK YTNNEAYFDVIEEIDAIIDKSGTTVFAEIQGYIDCLIKLSGMPDLTLTFINPRLLDDVSF HPCVRFKRWESERILSFVPPDGNFRLISYHIGAQNMVAIPVYLRHTMTFKEGSSGRLDIT IGPKQTMGKTVENIVVEIPFPKSVLNVTLTPSQGRCSFDPVTKVMTWDAGKMDVTKLPNI RGNINLQSGCPPPDSNPAINIKFSINQMAVSGIKVNRLDMYGEKYKPFKGVKYVTKAGKF QVR-MATIVKPDTRHATSDWFTSNYKISTDAERQRGASHDVRQEARFLRNETDNKTKWDQ LDNNTRLADRVDHIRLWKDKLEKTLADLDKEIADLSGSKDELENALEAKNLPLEMTCENL VTREGRKDIDLVEDEVEDEMHKEKAVIEAIQRQLQGKIDESFEQICVLQEARQQILADLQ DKNKALDIDVEQYNLTEDSPDISYKPNPTRVPKGSTTPDQWENFSRYNKERAEKEMGNSR RLREANHHTLQQTDNDLRSQQTATDYALRKRTHEFERALDELNWQKKQTEDEIAEMENDI RGLVDSVKAKTKPDKLAQTRLENRTYRPNVELCRDNVQYGLTDEVKQLETTKMSLAEKLK QSQHALHGLEQNLHRINADIALKTNSLKLDKDCQLSREKL---------TNLKDVLSDLI PEHQKIVKDFRSRHGSTKVGEVTVDMMYGGMRGIKGLVTETSVLDPEEGIEFRNYTIPQC QEILPKAAGGIEPLPESLFWLLLTGNVPTDAQAQAVSKEWANRAALPGHVVTMLNNFPSN LHPMAQFSAAITACNSESHFARAYNNGVKKNLYWEYVYEDSMDLIAKLPTIAAIIYRNLY RDGTSVGAIDDAKDWSHNFTSMLGYEDPEFTELMRLYLTIHSDHEGGNVSAHTCHLVGSA LSDPYLSYAAGMNGLAGPLHGLANQEVLLFLTKVSYSQAELKEYVWNHLKSGQVVPGYGH AVLRKTDPRYTCQREFAKKWLPNDPMFKLVSDLYKIVPDILLEQGKAKNPWPNVDAHSGV LLQYYGMTEMSYYTVLFGVSRALGCMASLVWDRALGLPIERPKSMST--------MPFQP PKTEKCTTCTKSVYAAERMEAGGNIYHKMCFKCTCCKMPLKLNNYQQSEGNLYCKNDYQK EILAKNAQIDHLFVHRDSQANNPDVAFEFTPENVERADAIIKNYPEGHQAAAVIPLLDIA QRQNGWLPISAMHYVAKYLQMPKMRVYEVATFYTMFNREPIGKYFVQICTTTPCILGGCG SDAILEAITKNIGIKPGQTTKDNMFTLMEVECLGACVNAPMVQINDNYYEDLTVEDINGI LDDIKAGKVPKAGPRSGQNGRFASEPKGGLTSLSTPPYGPGFKCRPDLMQKYERLEKIGE GTYGTVFKAKNRESQEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLYDVLHS EKKLTLVFEYCDQDLKKYFDSCNGEIDQDVVKSFLYQLLRGLEFCHSHNVLHRDLKPQNL LINKSGDLKLADFGLARAFGIPARCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIF AELANAGRPLFPGNDVDDQLKRIFKLLGTPTEETWPGMTQLPEYKPYPMYFVNPQVVPQL NARGRDLLLGLLVCNPGRRISAEEAMMHSYFADLNPSVKDGEKFFSYKGPVKGVTYPTSD VCDGWPLEYLEFHPNHEKGKIWIEENLSEKMQALYLKRQTRGGRGVIKTKKKQEPQRITL ARASRGKKKFVTVITGLATYDIDLKTASKYFAGVFACGSSVTGDDEIVIQGDCKDDLFDL LTEKWGQIDEDCIDDLGDQKRLFCSDRSAAWDEISSQLCSTLVARNSLLYGNEDIWRKLY FHPTQPEGLLAVQPHGYSGVSVPDKETMVTDAGKLHVLDNLLARLKSEGHRVLIYSQMTR MIDLLEEYMWHRKHTYMRLDGSSKISDRRDMVADFQNRSDIFAFLLSTRAGGLGINLTAA DTVIFYDSDWNPTVDLQAMDRAHRLGQTKQVTVYRLICKGTIEERILQRAKEKSEIQRMV ISGGNFKPDVLRPKEVVSLLLDDHEMEAKMSLETVPKDLRNLRACLLCSLVKTIDQFEYE GCENCDEYLHLKGNRDAVYECTSSSFEGIVSLMSPDDSWVAKWQRINRCVKGCYAVSVTG KLPPGIVRELKSKGVHYRSRDTSMPRFVPYLSKEQQEELRSIANAIVAPGKGILAADEST GTMGKRLSSINVENVEENRRQYRQLLFTALSNNISGVILFHETLYQKADDGTPFVKLLQD NNIIPGIKVDKGVVPLAGSDGECTTQGLDGLSERCAQYKKDGCGFVKWRCVLKIQSHTPS LQAMIENANVLARYASICQQNGLVPIVEPEVLPDGEHDLYTAQRITEEVLAFTYKALADH HVFLEGTLLKPNMVTAGQSCAKKFSAHEIAMATVTALQRTVPAAVPGITFLSGGQSEEDA TVNLDAINKKPWALTFSYGRALQASVLAAWKGSKDNVKSGQEELLKRAKANGEAALGQYA GGVQSAGGASLFVANHAYYIQSLPKVVKRRLKALKKLQFEMIKIESKFYEEVHDLECKYA AQYQPLYERRKEVLSGNVEPTDDDCDWPSEDEDEDEEEKVDGDENVTGVPEFWLTVFKNV DMLNDMVQEHDEPILKHLNDIKVKFSMGFSLEFHFEPNEFFTNSVLTKEYEMRTEADQDD PFSYEGPEIIKCKGCTIDWKKGKNVTVKLIKKTQKHKNRGTKRTITKTVQNDSFFNFFTP PDVPEGEADEDTEALLAADFEIGHFIRERIVPRAVLYFTGEALEDDDDEDD----IILLK EGTDTSQGRPQLIGNINACQAIVDAVRTTLGPRGMDKLIVDGQGKATISNDGATIMNLLD VVHPAAKTLVDIAKSQDSEVGDGTTSVVLLAGDFLKQCKPFIDEGVHPQVIVKAFRKATH LIVNRIKEIAVPVKKDPNELRELLLKCASTALSSKLVARQKNFFSKMVVDAVMALDVLLP LNMIGMKKVQGGGLEDSQLISGVAFKKTFSYAGFEMQPKAYKNLKIALLNIELELKAEKD NAEIRLDNVSEYQAVVDAEWKILYDKLDKIHQSGAKVVLSKLPIGDVATQYFADRDMFCA GRVDDQDLKRTMHACGGSIQTTVSNINLGMCEEFEEIQIGGERYNLFRGCPKAKTCTIIL RGGAEQFIEETERSLHDAIMIVRRAIKNDSIVAGGGAIEMELSKYLRDHSRTIPGKEQLL MGAMAKALEIIPHQLCDNAGFDATNILNKLRQKHAGTWYGVDINSEDIADNLVACVWEPS VVKINALTAASEAACLILSVDETIQNPRSNNPAPGMGRGR----KRNGMIPNSHFHKHWQ RRVKTWFAQPARKDRRRTLRAAKAAAIAPRPVAGPIRPMVRCPTFRYQTQVRAGRGFTYE ELKAVGINKREARSIGISVDHRRKNRSVESLQHNVQRLKEYKSKLILFPRKASAPKKGDA TEEEMKVATQHKGPIMPIKYSPPLPKARAVTAADKKFSAYCTLRVARANARLAGRRLKKA QDAMPNIKVFGGTSHRELAQKICDRLGIELGKVSTKKFSNQETSVEVGESVRGEDVYIVQ SGCGEINDMLMELLIMINACKIASSCRVTAVIPCFPYARQDKKDKSPISAKLVANMLSVA GADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENIAEWRNSIIVSPDAGGAKRVT SIADKLNVDFALIHKERKKANEVASMVLVGDVKDKVAILVDDMADTCGTFCHAAEKLVEA GASKVYAVCTHGILSGPALSRINESVFECVVVTNTTPQEERMKTCPKLQCIDISMILAEA VRRTHNGESVSYLFSNVPILHCRFYEHRFPEIEDVVMVTVRSIAEMGAYVHLLEYNNIEG MILLSELSRRRIRSINKLIRVGRNECVVVIRVDRDKGYIDLSKRRVSPEEVLKCEEKFAK AKCVNSILRHVGELMKFDSDEQLEELYRKTAWYFDKKYGKAGASYEAFKHAVTNPEVLDE LNLDERTHHVLLSNIRRRLTPQAVKIRSDIEVACYGYEGVDAVKASLTAGLDCSTEDMPI KINLIAPPLYVVTTQTLERIEGMARGQQKIQSQQKAAEKAAKMKTDSKKAAAAGLTFKCA VCMTQMPDPKTYKQHFENKHPKSPLPADLQ--MLGDLSSDLSRQGITTVPKGHCAKCAKP IIGQVITGLGKIWHPEHFTCYHCKEELGTQNFFERDGQPYCERDYHNLFSPRCASCGGPI LDKCVTALDTTWHPEHFACEQCGRIFGEGGFHEKDGKAYCREDYFDMFAPKCGGCQRPIM DNYISALNCQWHPECFVCYECRMPFGAGSFFDHEGMPYCETHYHARRGSLCAGCQKPITG RCITAMYKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCHPCFFKIFMRPLTDEETKIFFE KLSKYIGDNIRLLLERPDGSYCFRLHRDRIYYVSEKLMKTANNFRREDIVSAGTCFGKFT KSRKFRLQITALEYLAPYAKFKIWLKSSAEQQFLYGHHVMKSGLGRITENTSLYQGVIVY SMNDLPLGFGVAAKSATDCRHSDPMTIICFHQADIGEYIRHEDTLADQRKFFVGGNWKMN GNKASMDVIVSTLNEGNPNTEVVVSPPAPYLDYVRQKLIGVAAQNCYKAEKGAFTGDISP QMIKDVGCEWVILGHSERRHVFGESNQLIGEKTAFALQSGVKIIPCVGEKIEEREAGKTE EVVFSQTKAKDWTNVVLAYEPVWAIGTGKTASPAQAQEIHAKLRKWLNDNVSPAVAKSVR ILYGGSVSASNCRELAQQPDIDGFLVGGASLKPEFVQIINAREREGLLDPAWEKQQKKTF TAWCNSHLRKAGTAIENIDEDFRNGLKLMLLLEVISGEQLPKPDRGRMRFHKIANVNKAL QFIESKGVKLVSIGAEEIVDGNLKMTLGMIWTIIVQNFHLSFKDGLAFCALIHRHRPELI DYNKLSKDNPLENLNLAFDVAEKYLDIPRMLDAEDMVNSVKPDERSVMAYVSSYYHAFSG AQQAETAANRICKVLKINQENERLMEEYERMASDLLEWIRRTTPWLENRTTDNTLPGTQR KLEEFREYRRAHKPPKLEEKAKLETTFNTLQTRLRLSNRPAYIPTEGKMVSDIANAWKGL ERAEKGFEDWLLSELQRLERLDHLAQKFKHKCDIHEEWSTGKDEMLQAQDFKKCHLNDLK AMKRKHEAFESDLAAHQDRVEQIAAIAQELNTLGYHDVVSVNSRCQRICDQWDLLGNLTQ GRKNALEEAEHILERIDQLHLEFAKRAAPFNNWMDGAKEDLVDMFIVHTTEEIQGLIDAH EQFKQTLGEADKEYNSIISLVQEVQRISQQYGIMGGNENPYISITAQDIANKWAEVRQLV PQRDQTLQAEMIRQQNNERLRRQFAQKANVVGQWIERHLDMVASVGVQKGSLEDHLAKLH GVEGDVNAYRPNIADLERINEEVQEAMIFENSHTPYTMETLRVGWEQLLTSVARNINEVE NQILTRDSKGITNEQMEEFRKSFFHFDKSKSRRLEAKEFKSCLISLGYNIRDDRQGEADF QRIMSIVDPNNMGHVSFDAFLDFMTREATDNDTAEQVMQSFRILAADAPFITADILRREL PPDQAEYCIKRMAPFHGQGAPPGALDYTSFSTALYGESNVNKLSIDKIDVSGKRVLIRVD FNVPLKGSEITNNQRISAAVPTIKYALDKGAKSVVLMSHLGRPDGMRNEKFSLKPVAAEL KKLLGKDVLFLDDCVGKAAEEACASPAAGSVILLENLRFHVEEEGKGKDAQGNKVKADAA KVAEFRASLSKLGDVYVNDAFGTAHRAHSSMVGCQLPQKASGFLLKKELTYFAKALENPE RPFLAILGGAKVADKIQLIENMLDKVDEMIIGGGMAFTFLKVLNDMKIGNSLFDEDGAKI VKTLMEKAKSKNVKIHLPVDFVTGSKFGEDAEVGKATVESGVPEGWMGLDIGSASITQFV EAVGRAKTIVWNGPPGVFEFENFAQGTRGLMDAVVHSTSKGATSIIGGGDTATCCAKYKT EDKVSHVSTGGGASLE----------------MSGIPPTSWQPPNVAIETTMGSMMCELY WKQAPNTCRNFAELARRGYYNGIKFHRIISDFMIQGGDPTATGRGGASIYGPSFADEISN DLKHTGAGILSMANSGPDTNGSQFFITLGPTQWLDGKHTIFGRISNGMAVVKRIGMVETD NQDKPEEDIKITRHRSRSRDKKRNASPKRRKKPYKYWDVPPAGYEHMTPMQYKAMQGSIP FAGSAISRQARRLYVGNIPFGVTEEMMMDFFNTQMKMAALSQAEGNPVIACQVNLDKNFA FLEYRSVDETTHAMALDGINFQGQSLKIRRPKDYQPLPGIAETPNVGVVSTVVQDSAHKI FIGGLPNYLNEDQVKELLTSFGPLKAFSLVKDSATGLSKGYAFCEYLDQACAGLNGMQLG DKKLIVQRASVGAKNAASAPMQMQIPGLAVNPMATEVLCLMNMVLPEELEDEEEYEDILE DVKEECSKYGFVKSLEIPRPIKGVEVPGVGKIFVEFHSITDSQKAQNALSGRKFANRTVI TSYCDPDKYHRREFFMPLFDRVLVQRFAAETKTKGGVLIPEKAQEKVLKATVVAVGPGGR TDSGTVIPPCVVPGDKVMLPEYGGTKINLDNEEYFLFRDGDIMGK--RLLNQIPDIKSSL DIVTHMKSKKKPLSTQFRLSDNLYVKAKVPPTEKVCLWLGANVMLEYTLEAADELLQKNA AAESLEQVEEDLSFIRDQTTTVEVNMARVYNWDVKRKQ----MADEALARAGLHFDELNK IRVLEPEISQQTGELRDECKEFLDKISEFQKIVGSFVDLIDGVAKEVEKEKMKAIGSRNL LKSVTKQREAQQQQLLALITEKKVQLERLRIQHESLAKEELEQTDFIEQFILQK------ -------------------------------------------------LDKVTVKRLIT DNKTRRSKGIAYIEFHDVESVNLALGLTGQRLLGVPILVQPSQAEKNRASNAVGPMRLYV GSLHFNITEEMLRGIFDPFGKIDDIKLMKNHETGRSQGYGFITFHTAEDAKKALEQLNGF ELAGRPMKVGHVTERLGEPSALDTDDMDRAGIDLGATGRLQLMAKLAEGTGFEIPQVAAN ALNMNGAASAPPIATQCFMLSNMFDPITATTTWEIEIQDDVIEECNKHGGVLHIYVDKAS PQGNVYVKCPSISAAVASVNALHGRYFAGKVITAAYVPLPNYHSLFPDSIKSQNLVLSS- -----------PHSLIMHRRDGGQHSVHYMRAFIVLCVCAVI-----------------V IIAYLHSSARANLWPCMLMWESYSERDLVLFGDPGDNFYVIDAGEVDIFVNEEYVSTIGE AGSFGELALIYGTPRAATVKAKTDIKLWGIDRNSYRRILMGSTIRKRKMYEEFLSKVSIL ESLDKWERMTVADALEPVQFEDGQEIVRQGEPGDDFFIITEGSASVLQRQFENEDPVEVG KLGPSDYFGEIALLLDRPRAATVKACGVLKCVKMDRQRFERVLGPCGDILKRNIALYNSF VSLSVGSYRGLAKLHRLLFVAEHALSHVMTTYNSNMYQEIHKSLQDAITGNVPSLDTQWI ESTAKKAALKLEKLDTDLKNYKSNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDY CTSAKHVVNMCLNVIKVSVYLQNWSHVLSYVNKAESTPQVSENKDSGQAVVTRLKCAAGL AELATKKYKSAAKYFLQANFDHCEFPELISANNVAMYGALCALASFDRQELQKHVISSSS FKLFLELEPQLRDILHQFYDSKYASCLKLLHQIKDNLLLDLYLAPHVSALYTQIRNRALC QYFSPYASADMNRMASAFNTTVSALEDELMLLILDGQINARIDSHNKILYAKNDDQRNST FEKSVAMGVDYQRRSKALILRSAMWTNQIHVKSPPREGGQGGEMSLAPGNAASMSQRNEM VDKAEDVADQVLRRSKQFLPHVARLCIISTFLEDGIRMWFQWGEQRDYVNATWGCGWFLA VIFVMVNLIGQLACCAMVLSRKQVNIACFVLLGIIALQTVAYSILWDLKFLLRNVALTGG VILLLAESKAEGRSLFAGLPSLGENTPKTYLQLSGRILLVFMFLTLLRFEFSVFQMIQNI VGTALVVLIAIGYKTKLASLVLVAWLTALNFYLNAWWNIPDYKPMRDFLKYDFFQTLSVV GGLLLVVAMGPGGVSMDEHKKNWRQTVTMIPGDGIGPELMVTVKEVFSAAGVPVDFDEIF ASENLICLKGIISSPLHTLNMQIRRELDLFANVVLIRSLPGFVTRHNNLDFVIIRESTEG EYSSLEHESVEGVVESLKIITRANSERIAKFAFDYATKHGRKKVTAVHKANIMKLADGLF LESCANVSKFYPKIEFDSMIIDNTCMQLVSNPYQFDVMVMPNLYGNIVDNLAAGLVGGAG VVPGESFSEDVAVFEPGARHAAAEMAGRDQANPTGMLLCAANMLSHMNLGYYSSLIRNAV EKTIKAGKVRTRDMGGYATRSQFTMEVIKNLSEDFLRFIEKSSRYMERALCEQVDLFTDY VGEDGDDGPNEGEMLKLNRQFSDERWSKYRNVSCLDWSVIYPELLAASYFYNEDAPNDPD GVVLVWNMKYKKDTPEFIFHGPSAATSTCFAKFHPNLVVGGMYSGQIVLWDNRSNKRTPV QRTPLSSAAHTHPVYCVNVVGTQNAHNLISVSTDGKLCSWNLDMLSQPQESIELQHRQTK LAPTGFSFLSGDVNNFVVGGEEGAVYTACRHGSKAGITDVFEGHQGPLTGIDCHTAPGQI DFSQYFLSSSFDWTIKLWNIKENRALHSFEDNGDYVYDVRWSPVHPALFASVDGMGRLDM WNLNKDTEVPTASTRNVSLNKCLWHQSGHHIAAGDDMGTIHLYDVAETLSVPKVDEWSKF VHTLQDLKNMQDEQDEDNLQDHLIKATKIIEQQVDAEINRIDNMEEDDFEVLRRKRMQAM KKLQDQKQEWLAKGHGRYEEIADEKEFFDVCKKSRSVVCHFYRESTFRCQIIDKHLSILA PKHIETKFVKINVEKCKFLVERLRIVVLPTVCIAKEGKTTDYIVGFDDLGGSDEFPTEML EWRLGTTGVISYSGDLATPPVFGQNKKTIRGRNNDDRAIRLAGFGGIKMLKVQNVSTPAD GEVLIRVKAVGVNFADLMVRQGAIDNPPKTPFTMGSECSGEVEALGENVEGFQVGDRVIA VTHSWAELVARVFKMPTGMNYHDGAAFFMSYVTAYIMLFDIGNFREGQSVLIHSAGGGVG QALCQLSKNVTDATLFGTASAKHEAIKAK-LTHLYDH-SADYVQEIKKESPEGVDIVLDC LCGEDTNRGISILKPLGKYILYGSSNVVTGETKSFFSFAKSWWQVDKISPIKLYDENKCI SGFNLRQLLVVEKLFSLYNEGKIKPVIDSTWAFEDVGEAMQIMHDRKNVGKIVLDPAMMS RKQTPSDFLKQIIGRTVVVKLNSGVDYRGVLACLDGYMNIALEHTEEYVNGQLKNKYGDA FIRGNNVLYISTQKRR----------------ELNKHPVEGFSAGLIDDDDIYHWEVLII GPPDTPFEGGFFKAHLTFPKDYPLKPPKLRFVTDIWHPNIDKTGDVCISILHEPGEDKYG YERPEERWLPIHTVETIMVSVISMLTDPNDESPANIDAAKEWRENKSEFRKRVARCVRKS QE-TVRAENPLLRNTLKDFGAYVGECMPRFIQKVQVTAGNELEVLIHPDGLVPVITFLKD HTNAEFTNLADMCAVDVPSKPCRFELVYNFRSLRFNAMIRVRTYTDELTPVPSIYDIHRA ADWYEREVWDMFGVFFTGHPDLRRILTDYGFEGHPFRKDFPLCGYVEVRYDDEVQRVVVE PIEMAQEFRKFDYNSPWEQFPAFREKLNPYCQVDYRAKMWSCNFCFQRNQFPPQYSQISE QHQPAELIPQFSTIEYTLTRASANPPVFLIVLDTCMDEEDLQAVKESLQMSLSLLPPNAL IGLITFGKMVQVHDLSCEGYSKSYVFRGTKDLTAKQIQEMLGLGRGAPQLPANRFLQPVH KCDMTLTDLLGELQRDPWPVSQGKRPLRSTGVALSIAVGLLECTHPNTGARIMTFIGGAC TQGPGMVVGDELKNPIRSHHDIEKDNVKFMKKAMKHYETLANRSASNGHLIDLYSCALDQ TGLHEMKYLTNTTGGFMIMGDSFNTSLFKQTFQRVFSKDAKNEFRMNFSGNVEVKTSREL KVQGCIGSCFSLGTGPCVADNEMGIGNTSQWRMCGIYPNSTYAFFFEVVNQHNAPIPQGG RGYVQFITQYQHSSGQRRVRVTTVARNWVDASVSVQHLAAGFDQEASAVMMARLAVFRAE ADDGPDVLRWLDRMLIRLCQKFGDFNKDDPNSFRFSECFSLYPQFMFHLRRSQFLQVFNN SPDESAYCRHALMTEDLTQSLIMIQPILYAYSFSGPPEPVLLDTSSIKPDRILLCDTFFQ ILIYHGETVAQWRKAKYQEKPEYENFKQLLQAPMDDAQEILQTRFPMPRFIDTEAGGSQA RFLLSKVNPSQTHNNMYNDGSGLVLTDDVSLQVFMDHLKKLAVSTSSMSNLSHEEQLKLI SDLEIEMMADMYNRMTGACQKKCVPPKYNEADLNKGEAVCIDRCVAKYMDIHDRIGKKLT NISQQDEETVKKMQ-TQAPTVIHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYR KKVVLDGEEVQIDILDDYAAIRDNYFRSGEGFLCVFSITEQDSFQATNDFREQILRVKSD ENIPFLLVGNKMDLEEKRQVSIEDATARAQQWNVPYVETSAKTRANVDKVFFDLMRSIRV KKQADKRKKKKCIILKLYTGLREVVIDHLVNKVQSDVLESLNNNFLQTLNNSWNDHQTSM VMIRDILMYMDRVYVQQNSVDNVYNLGLMIFRDKVVRYPVIRSHLRDTLLDMVAKERRGE VVDRGAVKNACQMLMILGIDSRTVYEEDFERPFLEQSADFYKMESQRFLAENSASVYIKK VEARIHEEAERATHYLDKSTEDPIVKVLEDELICKHMKTIVEMEYSGVVHMLKNNKTEDL ECMYKLFIRVVEGLKTMCGCISGYLREQGKALVTEEEGGKNAISFVQSLLDLKDRFDHFL HQSFSDDRQFKQMISSDFEYFININPKSPEYLSLFIDDKLRKGVKGMTEQEIEAVLDKSM VLFRFLQEKDVFERYYKQHLAKRLLLNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFKD MTVSNTTMEEFKSHVQNTINLHGVDLLVRVLTTGFWPFQSASSKCNVPLAPRMAFEAFKK FYLGKHSGRQLSLQPQHGSADLNAIFYGARKGESGASSRARKHIIQVSTYQMVILMLFNN RDHWTYEEMKNESDIPERDLMRAVQSLALGKHTQRVLMKEPKSKEIEGSHVFMVNEQFTS KLHRVKIQTVAAKGESEPERKETRNKVEEDRKHEIEAAIVRIMKARKQMKHNVLVAEVTE QLKARFLPSPVVIKKRIEGLIERDYLARTPEDRKIYTYVADKIAVFPSRMAMTIMKARLT GAQKGHSLLKKKSDALTVRFRMILKKIIETKVLMGQVMKEASFSLAEAKFTMGDFNHLVL QNVNKAQVKVRSKKDNVAGVTLPVFESYQDGSDSYELTGLSKGGQQINRLKKNYSKAVEL LVELASLQTSFVTLDEVIKVTNRRVNAIEYVVIPRIERTLAYITTELDEREREEFFRLKK IQKKKGERRPANLLEDRDEDLLFPLRVLITGAAGQIAYSLLYSVAKGDVFGKNQPISLVL LDIDFMMGVLQGVVMELRDCALPLLHEIIPTADKNVAFKDIDVAILVGAMPRREGMERKD LLKANVKIFKEQGEAINTLAKKTVKVVVVGNPANTNAYVCKTFASSIPPENFTCLTRLDQ NRAAAQIAERQDVKNVIIWGNHSSTQFPDVSHATVVKDAIKNDSWLQGEFISTVQTRGAA VIAARKLSSAMSAAKAICDHLRDWWTGT-EGSWVSMGVPSDGYGIEKGLIYSFPVVIDHS YSIVQGLPISDFAREKMDVTQKELVEEKNDAM---SGNSGVLMVGPNFRVGKKIGCGNFG ELRLGKNLYNNEHVAIKLEPMKSRAPQLHLEYRFYKQLGQSEGVPQVYYFGPCGKYNALV LELLGPSLEDLFDLCDRKFSLKTVLMVAIQLITRMEYVHSKHLIYRDVKPENFLIGRQSN KKQHCIHIIDFGLAKEYIDPETHKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEAL GHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEELATYLRYVRRLD FFETPDYDYLRKLFTDLMTRSGWECDWEFDWTGRQIRHGGSVQVVSSTNGELN-T-GHSN TPITAPVDVEVVDETK--MATTRPFTCEDMFKFSCTNLDPLTETYALAFYMQYLAHWPEY FQVVESHDGKIMGYIMGKSEGHAENWHGHVTALTVAPEYRRLGLAAKLMNVLEEISENRF CFFVDLFVRVSNQVAVDMYKRLGYSVYRRVIEYYSGDPDEDAFDMRKALSRDVEKRSVQP LAHPVRPEDLDQQLDCALDLMRRLPPQQIEKNLSDLIDLVPDLCEDLLSSVDQPLKIARD EEAGKDYLLCDYNRDGDSYRSPWSNKYDPPLDDGAIPSARLRKLEVQANQAFDQYREMYF EGGISSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVIEVQEKA--RASHYKLTST VMLWLQTTKSGSGTMNLGGSLTRQSSTDRPTPEMQSHIVNIGQLIEEMENMMRSTLNEIY FGKTRDVVNDLRMLMSQKQKDLRAEMESALKSR--FDKEFDD-EEPLDETNDQGQVEILP VAQKVDKEKRMTTPYMTKYERARVLGTRALQIAMCAPVMVELEGEKDPLQIAMKELKARK IPIIIRRYLPDGSYEDWGIDELIISDRQATLKERAMAPASDKAFNIGKGMVAGASALGLG GLCFYGLGLSNEVGAIDRAVIWPEVVRHRIRDTYAYFGGSIFFTALSRSPRMMALVMNYG WKSLLGTVAAMWGSGWLCMSIPYESGAKQLAWILHSSVVGAVVAPMTMLGGPLLLRAAVY TAGVVGGLSALAMCAPSDKFLNMGGPLAMGLGVVFASSMGTWFLPPSTALGAGMYSVAVY GGLVLFGMFLLYDTQKIIKRAETHPVVSYQRFDPINNSVGIFMDTINIFIRIAMILAGGG NRRKMEIVYVYTKKRAEFGRQCNFSDRAAELHVDIVPDASLMESFIERNPVDRGTQCVQE MSEHEINTERYETDTRGINHTEGGWPKDVNPSEIEQVMRYRKKVEKDENYIYTLQGLAGV VEKCIRQNNAIDIYEEYFENIDVEEAEEPPSARTINVFRDPNEKKRTATHISWYPDGPKK LAIAHCNLDFQGSDPETMESYIWDIENPNKPEMTLKPVSPLVCLEYNPKDSHILLGGQYN GQIAFWDTRKGSQPAEVSPIEHSHKDPAYKTIWIQSKTGNECFSASSDGQVLWWDIRKMG EPTEVLYLDPTKKQDITKVHGAMTLEYEPTMPTKFMVGTEQGTVMSCNRKAKTPGEKIVA LYPGHYGPIYALQRNPFFPKNFLTIGDWTARIWSEDIRDSSIMWTKNHTSYLTDGCWSPL RPAVFFTTKKNGTLDIWDFIFKQNDPTLSLQVCDEALHSIRVQDNGRLIATGSHSGTTTL LELSDGLCSLQRNEKALVTAMFERETRREKILDARHREMKLKERTKSSWETLVSRVTTIS KPLASRKLSKKLYKCMKNALRKGVREVQKFLKRGEKGFVVLAGDTNPIDVICHVPIMCEE KSIPYCYTPSKQHIGNAYGSMRSTCMVLVKSHEDYEELFDQCFADLKAMPMPLMPAENLE EQGLAKNPNLELAQWKFLLTTDNFKNDESVKSKLMAEIKAENMAPFYEEVCRDLGWKLDQ SLLTKMKEANEVKIKELDSAIEDAENNLGETEVRDTMLRKAEYYSMIGAKEQVLSQYRKV GEKTVTLGYRLDMVFHQIRLGLFYMDHDLIKRNLEKAQTMIDEGGDWDRRNRLKVYRGTY CMAIRDFKAAAQLFLDTIATFTSYELMDYQQFVAYTVFCCMIALDRPVLREKVVRGAEIL EVLHSLTDVKQYLFSLYTCQYKEFFQTLALVEQKMRYDRYLACHYRYYTREMRIQAYSQL LESYQSLTLDYMAKAFGVTPNFIDQELSRFIAAGRLHCKIDKVGGIVETNRPDSKNYQYQ ETIKRGDILLNRIQKLSRVINVRRGFRSTKEVIPGVAYSNLTIGVPKETLNLEKRVALVP ATCATLKKGFSVNIEENAGIGAKFSNAEYEAAGAKVSTKDAFQSDIVFKVQKPNMQEVAA LREQNTLYSFLYPAQNKELVDALAARKSTVFAMDCVPRISRAQTYDALSSMANIAGYKAV LLAANSFGRFFTGQITAAGKVPPAKILVIGGGVAGLSAMGTAKNMGAIVRAFDTRAAVKE QVQSMGAEFLELNYEESGEGAGGYAKEMSPEFIKAEMELFHKQCKEVDILISTALIPGKK APVLITREMIESMKPGSVVVDLAAEAGGNIETTRPGEEYVYKDVTHIGYTDLPSRLPTQS STLYANNVSKMMLSFGYNPTLEDDVVRGSMVLDKGKLLWPPPAKVEPNYFGNTMKDSLMY TAGLSSVLGLGVIAPTPAFTTMVTTFGLSGIVGYHTVWGVVPALHSPLMSVTNAISGITA VGGLLLMGGGIMPSNTIQGLAAAAAFISSINIGGGFLVTKRMLDMFRRPDDPPEYNYLYL IPSGSFLGGYFLASMGAYPHIHQMTYLAASLCCVGALTGLSRQDTCRIGNNLGLIGVSSG LAATVGLLNPAPDVLAQMMGCMGTGGLIGAIMAKRLEVTDLPQMVALFHSLVGAAAVITC VANHMAEQPHFDTDPAASVMKTALFLGTYIGGVTFTGSLVAFGKLQGLLKSDPLMLPGRH MLNAALMAGNVGAMGYYMMSNDTVGMSMLGTTTALSSVMGITLTMAIGGADMPVVITVLN SYSGWALCAEGFMLNNNLMTVVGAMIGSSGAILSYIMCVAMNRSLPNVILGGFGTSSYAG GEAMKITGTHTECNAAETVEMLTEAQNIMIVPGYGLCVAKAQYPIAELVSLLRSKGKNVR FGVHPVAGRMPGQLNVLLAEAGVPYDIVHEMEEINDDMPDVDVTLVVGANDTVNSAAEED PNSIIAGMPVIRVWLSGQVVVMKRSLGVGYAAVDNPIFFKENTSMLLGDAKKSCDALLQK TKMERPSVAAGCPPGLEYLTQIDQLVVKQQVEIMELITSWECANKYRVMNSVGQQVYFAQ EESETCMRQCCGPSRSFIIHITDNAGREVLRLKRDFKCCAGLCWCAGCSHEVVVESPVGQ IIGYVRHSAWRPKFTLYTGIGHIKGPLCICKGPCC-GDIDFPVMSTKIGNVAKQWSGALR EFFTDADTFSISFPMDMDVKMKGVMIGALFLIDFMFFEESKNKVDPELAEFVNMEQQKQM IQGQVHKLTDTCWEKCMDKPKDKLDYRTEGCISNCVDRFMDTTVAIAGRFQQLMQKQMMG RSEGLVQRRNVAQEEEDGDSKETRFTLLEEVLLLGLKDREGYTSFWNDCISSGLRGCILI ELGLRGRVELEKTGMRRRLLANRKIICKNDQPTGDVLLDEALKHIKETQPPETTQSWIEY LSGETWNPLKLRYQLRNVRERLAKNLVEKGVCTTEKQNFLLFDMTTHPLKENTIKGKLIK RVQESVLSRWVNDPHRMDRRTLSLIYLAHASDVLENAFAPLSDDDYEVAMKRVRDLLDLD FEQETMKDGTCELMWAVVSAFSKAKKISTVTSDNCEVCLSFMTKFIDGLDKIEAEFRKIC KSTKKDDNRFCYYVGGLDESATGILGEMSKPVSWGVPAEKVCLKLYRKDEQICELKYDKQ LDLKNVDLKKLRVKELKAILTEWDEKCKGCTEKDDYVRLIEELMPRYAPEAH---ILKGF KLNWMNLRDADSGKILWQSSDDLSIPEQEHEARVPKKILKCRAVSREINFSSKEQMEKFR LQQRVVFKGKCLEQWFFEFGFVIPDSTNTWQSIIEAAPENMMMPANVLNGNVIIETEFYD GDLLVSTSRVRVFYVMAKVVSKSVVCTDTRDQEEYQAEKPLHVYYCLCGHMSLILDCLLE KLPLRSRDGARVVDSNKHAHKITCDMDETVYLKRPDGIERQYRFKCKSCSLWLYYRHKNI VTFVVEGALKL-GEVKKDVYSQISEPKKVMVKRSTKDMGKFSSVTVSTVDEEEDEMEAKE IAESYAANAKVIEKQLMRRGLTKRKLLEEAE-EAKKLRPKGTLIDIARNVARLAAQQQSR NYADMSFTFASPAEINVAQVDVPSMTGSFGILPQHVPALAVLKPGVVTVFEGDGASKKFF VSSGSITINDDSSVQILAEEAVPVEHLDSQAAREGLSLAQQEASTEQAKAEAQIAVECFE EVIKVAECKYFATELKDRLAASAKSKEMIETGHGLERKKRFQYLTSELRLTEALLEPHIC ENILNYNVHAERKGSLRYAKGMSETFQTLHGLVDKGVKVDLGIPYDLWDKPSAEVSKMHR WCFNLAEQYEEDIEDWYYHHQKDLFDYLCRERYLKHKQS-FSATDVTSEADVLAAILAKK QFGAPQVGVNCAGIGIATVTYNAKKDRVHSLEEYERVVKVNAAGSFNVMRLLAKEFAHNE PNSDGQRGVLVNTASVAAFDGQRGQAAYSASKGAIVGMTLPIARDLASLGIRVNTIAPGL FRTPLLMGLPEKVQTFLASTVPFPSRLGDPGEYAHLVQFLVENPMMNGETIRCDGAIR-- ----------------VSRDYPIVDHEYDALVVGAGGAGLRAAFGLSSLGFKTACITKLF PTRSHTVAAQGGINAALGNIESDKWEYHFYDTVKGSDWLGDQNAIQYMCEQAPASVIELE NYGMPFSRLENGRIYQRAFGGQSLDYGAGGQAHRACCVADRTGHSMLHTLYGRSLHYDTD YFIEYFAQDLIMEDGICKGVTAISLEDGNIHRFRANNTVLATGGYGRAYFSCTAAHTCTG DGTAMVSRAGLANEDMEFVQFHPTGM----------LFDMRDYRV--EGERFMERYAPTA KDLASRDVVSRAETIEIREGRGVGPEKDHCYLQLSHLPPDQLHARLPGISETAQIFAGVD VTREPVPVIPTVHYNMGGVPTNFNGQVIQCDDVDSIVPGLYAAGEAACVSVHGANRLGAN SLLDLVVFGRACALNIAENNKPGDKAPTIKENAGEETVAYIDKLRYSNGSTPTADLRLRM QKAMQTYAAVFRDGPTLVEGCKQMDSLYQEMDIKVSDRGMVWNSDLIETLELQNLMLNAL QTIVSAENRKESRGAHSREDFPTRIDEYDYSKSVEGQTKKPVEEHWRKHTMSFIDQDTGK VKIDYRPVVDTVLDDKKINTIPPKLRSYMTALSQEEVINNTKTVVQGLETLQNEHHQILN SLLSSMKTIKRGDTNLVEEKSNILKKSLELIDLGLGESQVMMALANHLQYVEAEKQKLRA QVRRLCQENAWLRDELANTQQRLQHSEQQVATLEEERKHLEFMNEMKKYDSDSVLGFP-D DDDVGPSAMAQAASGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHD HPDVATMLNILALVYRDQGKYKEAANLLNDALGIREKTLGPDHPAVAATLNNLAVLYGKR GKYKEAEPLCKRALLIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEQYYQRALEIYE TKLGPDDPNVAKTKNNLASAYLKQGKYKQKIAARYDSDVEREVLGWFKQLLNAGMNNVQR ALHSGVDLVKLALEVAAKKMRLKPNTLSAPFKQMENIQVFLNFCEKMGMSKTSLFQTVDL YEGRNMAQFLTAVQQLGSECQRYGFDGPVIGSRPTEKNIREFTEEQLKAGNLQAGTNKCA SQAMGGVRHIADIKADDLCREGTGVIGLQSGNKGASQSGMSMGAVRHVSDIRADEMDKDG QGVIGLQAGSNKGASQAGMSMGAVRHVSDIRADEMDKDGQGVIGLQAGSNKGASQSGMAM GSVRHVSDIRADDMSDGQGVIGLQAGSNKGASQSGMSMGSVRHVSDIKSGQGEGQAIIGL QAGSNKGATQSGMSMGANRMVSDIKTGKMSSHGVTSLQYGSTDGASQSGMSFGGARNI-P QTHSFGIEPITCHAWNKDRSQIALLNDSDVKIFSCNWTLTHTLSEHQERVTGIDWAPGSN RIVTCGADRNAYVWPTLVILRINRAATCVKWSPKENKFAVGSGARLISVCYFEQENDWWV SKRIKKPIRSTVTCLDWHPNNILLAAGSTDFKTRVFSGYVKEVESKPEAGSWGKKMILGN LMAEFSNGGGWVHDVSFSASGDKLAWVGHDSSVSVAQAFSKTIYRPFVTCTWINESNVLT AGHDCYPLVFSHSKGALTMAGKLDDQKFSALKHFKALDSRATTLGSVHQNTILQASIHSG SKAGALKVCTTSVDGLLAIWDLKKEIEGYVGFANLPNQVYRKAVKKGFDFTLMAVGESGL GKSTMINSMFLTDLYNAEHPGPSRRLKKTIAVESNQVLLKENGVQLRLTMVDTPGFGDAV DNSNCWDPVIDYVESQYDSFLNSESRVNRKSLPDSRVHCCLYFISPNGHGLKPLDIEFMK NLHDKVNIIPIIAKADTLTYDECREFKKTILNEIAQNKIRIYEFDDEEEQKVTKKLRERV PFAVVGSNAVVDCGGKKSRGRVYPWGTVEVENLMHNDFLALRDMVIRTHMQDLKDVTNNV HYENFRYHKLAAFSRSPIVQMEEEKKEHIQKMKKMEAEMEQVFEMKVKEKKQKLKDSETD LSRRAEQMHRNLEQQEKEMEERRATFEKERQMWDDQQSMSRRYDSRTTIFSPEGRLYQVE YAMEAIGHAGTCLGILATDGIVLAAEKRSTNKLLDEVSFSEKIYILYEDMACSLAGITSD ANVLTNQLRLIAQRYSLQYQEPIPCEQVVSTLCDIKQAYTQFGGKRPFGVSILYMGWDRH YGYQLYQSDPSGNYSGWKATCIGNNSAAAVSLLKQDYKEGETDMPTALELSVKVLGKTLD TNKLTPDKVEIATLSRQDGKTVIRILPASEVEVLIKKHDEQVAKLEAEKKKELNEGWERL KSLALKRQERLFGAHEIQNFNRDADETIVWIAEKDTTLSTDDYGRDLANVQALQRKHDTV ERDLAALEEKVKTLANEAERLKETHPDQAEEIDKKQADIENNWRMLKSKSEERRARLDDS YNLHRFLSDYRDLISWIHDMKTIISADELAKDVTGAEALLERHQEHKGEIDAREDSFRLT AEAGNRLLESDHYATDEVKEKLITLANEKTSLLDLWEQRRILYEQCMDLRLFYRDTEQAD AWIAKQEAFLANEDLGDSLDSVEALVKKHEDFEKSLAAQEEKIKALDEFATKLIENEHYA ADDVAARRDALLQRRNALHDKATMRRLRLEESYKYQMFERDFDETKIWINEKLKAASDEG YLDPTNLQGKLQKHQNFEAELSANEPRIDEVTRNGEELINADHYAKEPIQDHVSEIQNLW KQLNEQSERKGHKLKGASDQQQYNRNVEDFEVWMADIEGSLMSEDYGKDLTSVQNLQKKH ALLEADVGSRLDRIDNIEQQAANFVESAHFDQDTIVAKKVNLVERYKSLVDPIKAKRSKL GDALRMQQFVRDVEDEEDWIREKEPIVASTNRGRDLIGVQNLMKKHQALQAEIGGHDPRI QNVCDQGKEMMDEGHFASEEIAKKCQGLTDRWNSLKDKSNQRSQDLEDSLQAQQYFADAH EAETWMREKEPIVGNMDYGKDEDSAEALLKKHDALMSDIDAYEQVIDGLKEQATACKQQE APVIDDIGKECVVAVYEYQEKSPREVSMKKGDVLTLLNSSNKDWWKVEVNDRQGFVPAAY VKKIDSSLTASQSNLADEFTIVVRQGQIENQYANLKDLGRQRREKLEESCKAYQLVREAG ELAQWIDNKERVALAEEVGDDLEQVEVIQRKFDDFQKDLKANETRLVELNTIAERLTAMG QTEAAEKIKIQIEDLNQRWAALQQVTVERAQTLGSAHEVQRYHRDADETKDWIEEKELTL NIDDLGHDLTTVQRLQRKHEGLERDLAALGEKVKDLDQTAERLMSTHPDQAQSIYDHQKE ITERWNLLTEKADTRKAKLLDSYDLQRFLSDSRDLMSWINSMMALVSSDELAKDVTGAEA LLERHQEHRMEIDARAGTFQAFEMFGHQLLQNNHYASEQVDDKLKELTEARKALEDAWIA RRAKLDQCLELQLFQRDCELAETWMAAREASLADSVDGSDSVEALLKKHEDFDRAINSQE EKIAALQSFATQLTSNDHYDTPGVEQRRDDVLERWRKLKENLLENRAKLGEAQSLQQFSR DVDEMEIWITEKVAMASEESYKDPSNIQAKHQKHQAFEAELAANSDRISAVLKMGEKLVD DQQCSGSETAVQERIQKLVEEWEFLTSKTSEKSDKLKEANRQRQYTAAVKDLEFWLGEVE DIVDNEDYGKDLATVQNLNHKHQLIDADVKAHDDRIRDLNEQADAFIDSGIWDTESIKEK KQSINERYERVKTLTAHRRARLDEANTLHQFFRDIDDEEAWIKEKKLLVGSDDYGRDLTG VQNLRKKHKRLEAELNSHKPAIQAVQDTGEQLMSESNLMKDDIAQRLSQLADNWDELNQM ASDRAKKLDESLAYQQFAATVEEEEAWITEKQHLLSGDDYGDTLAAVQGLLKKHDAFTTD CQVHKDRCVEVTKEGDQLIEDGNHNAEQIKVRCQALQDKLNSLEEAAGGRRARLVDNSAF LQFIWKTDVVESWIADKETQVRSEDYGRDLSSVQTLLTKQETFDAGLQAFEKEGIQTITA LKEQLVESKHAQTPAIEKRYSDVITRWQSLLSDSDGRKQRLLRLQEQYRQVEELYLTFAK KASAFNSWFENAEEDLTDPVRCNSVEEIKALREAHDQFKASLSAAEADFNQLAQLDKQIK SFNVGPNPYTWFTMEALEDTWRNLQKIIKERDDELIKEQQRQEENDQLCKQFAQAANAFH QWLTETRSAMMEGTGSLEAQLEATKGKSVEVRANRNQLKDLEDLSAAMEERLILDNRYTE YSTVGLAQQWDQLDQLGMRMQHNLEQQIQACNQSGVTEDALREFSMMFKHFDKDKSGKLD HQEFKSCLRALGYDLPMVEEGQRDPEFESILDVVDPNRDDFVSLQEYMAFMISRETENVQ SAKEVEAAFRALTSAEKPYITATELYANLTKEQADYCISRMKPYVDHTGRQILEAYDYVD FTQLLFINAIQCYQCDSNEDQSCPSERPFDRNLNALVDCNSFEARTPGTFCMKITQQSPG WQGWKKVTRRCGSRSDTGVAWGCRWEYEENGVWKEVCYCEDRDGCNAASNIDKDDGDNPQ LVSEYVQDIYKYMHSLEVRELNGRMRGILVDWLVQVHLRFHLLPETLYLTVAIIDRFLQV AVPKTKLQLVGVTSMLIASKYEEMYAPEVNDFVYITDKAYTRSDIIRMEIVILKALDFEL GRPLPLHFLRRNSKAGEVDADKHTLAKYLMELCLVDYECVHHRPSLIAAAALCLSIRLLD WTDTLEYYSTYRQDQLDPVIHRMSHLVMCKTTAIKTKYSSQKFMRISTLAELSGPVIEQL ARGGKSRGRRQNNPSPGPENDLERVFIWDLDETIIIFHSLMTGTFAQRFGKDVPRGVTAG MRMEELIFSLSDTHLFFNDLEECDQVHIDDVSSDDNGQDLSNYNFATDGFHAAATNNLCL ATGVRGGVDWMRKLAFRYRRIKEIYSSYRNNVGGLLGPQKREQWLELRSEIEALTDNWLT LALKNLAIINQRSSCVNVIVSTTQLVPILAKVLLYGLGGVFNIENIYSATKIGKESCFER IVSRFGRKCTYVVIGDGRDEEAAAKQMNWPFWRISNHSDLMAFHHALLEEYLQSALSVGG VRTTGESVRTQNVMAAASIANIVKSSLGPVGLDKMLVDDVGDVTITNDGATILKLLEVEH PAAKVLVELAQLQDQEVGDGTTSVVIIAAELLKNADELVKCKIHPTSIISGYRLACKEAC KYIQENMTIKVDELCRDSLISAAKTSMSSKIIGSDMDFFSTMVVDAAQAVKTSDGKGGFR YPVKAVNVLKAHGASSRESLLIHGYALNCTVASQAMVKKVTGAKIACLDFSLQKAKMKLG VQLLIDDPTQLEAMRKRESDITKERIQKILATGVNVVLTTGGIDDLCLKYFVEAGAMAVR RCKKAEVPDVCMGIAAQLVVTLANLEGDETFDASMLGQAEEVVQERICDDELLLIKKPKV RSAASIILRGANDFMVDEMERSIHDALCVVKRVMESKSVVPGGGAVEAALSIYLENFATS LSSREQLAIAEFARSLLTIPKQLAVNAAQDSTELVAKLRAYHNTSQTKAEHKDLKWVGLD LVEGIVRDSKKAGVFEPAISKIKSLKFATEAAITILRIDDMIKLAAEERSGRSYRDAMKA GMLDADNARLLAAKNILNEILVEGRDLTVQYNIFNVGGSAAREVSLTDASFPESDFEVIQ GSLEVNWNRLAPGSNVSHAVILRPTKSGYFNFTSAEISYLASEEERQIGYTSGPGEGGIM HHRDYDRKFSPHVIDWAAFAVMTLPSLGIPFLLWFSSKSKYDKPRASK-GSSSHKDKIEK YRAVLELLEKLRFFVEALVNENVSLVISRQLLSEFCTSLSKLDNVLAKDIAHYSLEKIQP RAISFEEQVASIRQYLATLYEQQQKWKEAADVLVGIPLETAQKQYKSDYKLETYLKIARL YLENEEPVQAEAYINRASLLQADSKNEQLQIYYKVCYARVLDYRRKFIEAAQRYNELSYK TVVAESERMTALKNALMCTILASAGQQRSRMLATLFKDERCQQLPAYSILEKMYLDRIIR SEELQEFSELLLQHQKAVTSDGSTILDRAVIEHNLLSASKLYNNISFEELGALLAIPPMI AEKIASQMITEGRMDGHIDQIDSIVHFEARVALPRWDVQIQSLCFQVNNIIEKITQSAPE WMGK-------MKLTDTVVRNFRVAKVFKENNDKINSIDFSSNGETLISSSDDDSIVIYD CQNGAPKRTLNSKKYGVDLIHYTHATNTAVHSSTKVDDTIRYLSLHDNKYIRYFQGHTAK VVTLCMSPIDDTFLSGSLDKTIRLWDLRSPNCQGLMHLPGRPVAGFDPEGLIFAAGINSE YLKLYDLRSFDKGPFATFKLQQDKDCDWTGLKFSPDGKLILISTNGQVVRLIDAFQGTPL QTFMGQTNHKGIALEASFSPDSQFVFSGATDGKVHCWNTETGAKVGILNGDHQGPVTCVQ FNPKYMMLATCCNSMGFWLPQVDEKYILVDKRGEKKNVGFVQLNRPKALNALFEPLMCEL NAALKDFDLDPEVGAVVITGSERAFAAGADIKEMLPKEYSDVYKNNFLMHWAEMTNRKKP IIAAVNGYALGGGCEVAMMCDIIYAGEKAKFGQPEITIGTIPGAGGSQRLTKAIGKAKAM EMVLTGDPITAQEAEKAGLVARIYPADQLVDESIKKAERICQHSKIIVQMAKEAVNASFE MPLREGLKFESRFFHQTFATGDRKEGMGAFVEKRAPDFKD >Carinoma_mutabilis MTDRKAVIKNADMTEDMQQDAVDCATTALEKFNIEKDIAAYIKKEFDKKYNPTWHAIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSGINSQIRSLQTSSVQRDIDQAAKYIGAGAATV GCAGAGAGIGSVFGNLVIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLILFAFM SYIKEAGKGQEAPVHRIRITLTSRNVKSLEKVCADLIRGAKDKNLKVKGPVRMPTKILRI TTRKTPCGEGSKTWDRFQLRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADMDQVM QFIEPAKQFSKDSIRLVKRCTKPDRKEFQKIAMATAIGFGIMGFIGFFVKLIHIPINNII VMAAQISKKRKFVADGVFKAELNEFLTRELAEDGYSGVEVRVTPTRTEIIILATRTQQVL GEKGRRIRELTSVVQKRFNFPEGTVELYAEKVATRGLCAIAQCESLRYKLIGGLAVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGEPTNDYVDTAVRHVLLRQ GVLGIKVKIMLPWDPTGKLGPKKPLPDHVSIVEPKDEVIPAQPYSEQKGGK---RGRGGS SGGNFLISLALPVGAGMNCADNTGGKNLYVIAVKGIRGRLNRLPAAGSGDMVMATVKKGK PESRKKVMPAVVVRQIKSIRRKNGVFIYFEDNAGVIVNNKGEMKGSAITGPVAKECADLW PRIASNASSIRKGKVHKVSLGPQVVEGENVFGVAHIYASFNDTFVHITDLSGKETIVRVT GGMKVKADRDEASPYAAMLAAQDVAERCKQLGITALHIKLRATGGNKTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRLMGKPRGLRTARKLRNHRRDQRWADKD YKKAHLGTRYKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP NDGCLNFIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKEKKERPRTEQV ATLRTRKFMSNRLLCRKQMVVDVLHPGRATVPKTEVREKLARMYKTTADVIFCFGFKTKF GGGKTTGFALVYDTLDFAKKFEPKHRQVRHGSRKQKKERKNRQKKVRGTAKAKVG-XXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXMGSVFAKLFSGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERISEAKDELNRMLGEDELRD AALLVFANKQDLPNAMNAAEITDKLGLHSLRNRHWYIQATCATSGDGLYEGLDWLSQTLK ---MPLARDLLHPSLDEEKRKCKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRRKQHMVRMNVLADALKSICNAEKRGKRQVLIRPRSKV IVKFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVPIRHIEKWTSNL LPSRQFGFLVLTTSGGIMDHEEARRKHLGGKILGFFFMGRMHAPGKGISQSALPYRRSVP VWLKLTPDDVKDQIYKLAKKGLHPSQIGVILRDSHGVAQVRFITGNQILRILKAKGLAPE LPEDLYSLIKKAVAIRKHLERNRKDRDAKFRLILVESRIHRLARYYKTKKILAPNWKYDS STASALVAVAELPEIKLFNRWSSDDVQVSDISLTDYIAVKEKYSKYLPHSAGRYQVKRFR KAQCPIVERLTSSLMMHGRNNGKKLLAMRIVKHAFEIIHLLTGENPLQVLVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGARESAFRNIKTIAECLADELINAAK GSSNSYAIKKKDELERVAKSNRMAEQMTLRGTLKGHNGWVTQIATTPVLPDMILSASRDK SIIVWELKRDGNYGFAKSSLRGHNHFVSDVVISSDGQFALSGSWDNTLRLWDINASTTTR RFVGHTKDVLSVAFSSDNRQIVSGSRDRSIKLWNTLGVCKYTIDEGHDSWVSCVRFSPNT SVPIIVSCGWDRLVKVWNLTNCRLKTNHHGHHGYLKCVTVSPDGSLCASGGKDGSAMLWD LNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLXGKIVVDELRQETLNAS-- PPTCTSLXWSSDGQTLFAXYTDNLIRVWQVS----XXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXMSDAEGDDVPT--SAAGPMDVNTALQEVLKTSISVDGLARGIREC TKALDKRQAHVCILANNCDEPSYVKLVEALCAEHGINLLKVDDNKKLGEWSGLCKIDKEG KARKVVGCSCVVVRDYGKDTLAQDVLQEYFKKR-XXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFSTSAKILKPQGEKPDEFESTISQ ALLELETNSDLKASLRELYITGAKEVEIMGKKAIIIFVPVPQMRAYQKIQTRLIRELEKK FSGKHVVFIAQRRILPKPTRKMKTKSKQKRPISRTLTSVHDAILDDLCFPAEIVGKRIRI KLDGSRLIKVHLDKSQQTNIEHKLDTFSGVYKKLTGKDVTFEFPEFVLGRGGFRGGFGGR GRGRGRGRGRGKDGDKEWVPVTKLGRLVKDMKIKSLEEIYLFSLPIKEFEIIDYFLESSL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDHNGHVGLGVKCSKEVATAIRGAIILAKLSV IPVRRGYWGNKIGKPHTVPCKVTGKCGSVVVRLIPAPRGTGIVSAPVPRKLLTMAGIEDC YTSASGQTATLGNFAKATYYAIASTYSYLTPDLWKETVFTKSPYQEFTDYLAKMSGGLDV LGLKEEDVTKFLACGTHLGSTNADYQMEQYVYKRKSDGTNIINLRKTWEKLLIAARAIAA IENPADICVISARPYGQRAVLKFASSTGSTPVAGRFTPGTFTNQIQAAFREPRLLVVTDP RTDHQPVVEASYVNIPVIALCNTDSPLRYVDIAIPCNNKGNHSIGLMWWMLAREVLRLRG SISREVPWDVMVDLYFYRDPEEAEKEPKEEDWGSEPLNVPFPVTTEDWGA--ESEWGNTQ MTTEWGGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXX-SPSSTNVGSTVRQRKTTTSGGGGAGMWRFYTEDSPG IKVGPVPVLVMSLLFIASVFMLHIWGKYTR-KGDNKKKSTFNEVVTRECTVNVHKRIHGM GFKRRAPRAIKEIRKFAHKMMGTPDVRIDTRLNKHMWSQGVRNVPYRVRVRLARKRNEDE DSTHRLYTLVTYVPVATFKGTQTINVDNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNQDRLTKRIGGKGTPRRKKKTIHRSSTTD DKKLQTTLKKLGVNGIQGIEEVNMMKDDGTVLHFNNPKVQASLGANTFAITGHAESKPIT NLLPSILNQLGAESLDHLRKIAEVTDEVD-DDDDVPDLVGNFDEASKDEMTRYSLDPENV AKSAKARGSHLRVHFKNTRETAQAVKHMHLARAKKFLKNVQDKKEIVPFRRFSGGIGRHA QAKQWKATQGRWPKKSAAFLLDLLKNAESNAEYKGLDVDHLVIDHIQVNRAPQMRRRTYR AHGRINPYMSSPCHIEVILSEKEQAVAKPVKKKVSQKKLKRKKMMAREKKACPNPELTEE QKQEIQEAFDLFDAAGSGTIDTKELKVAMRALGFEPKKEEIKKMIADIDKENTGQIDFND FLTMMTQKMSEKDIKEEILKAFRLFDDDNTGKISFKNLKRVAKELGENLTDEELQEADRD GDGEINEGEFLRIMKKTSLYMGISRDKWHKRRKTGGRREPIRKKRKFELGRPAANTKLGV KRIHSVRTRGGNKKYRALRLDTGNFSWGSESQTRKTRIIDVVYNASNNELVRTKTLVKGA IVQIDATPFRQWYESHYAMPLGRKKGAKLTEAEEAVLNKRSKKTQAKYDERKKIAEVDIA LDEQFATGRLLASISSRPGQCGRCDGYVLEGKELDFYGKKMKQKKGKMSLVIPEKFQHIL RVMNTNIDGRRKIMFAMTAIKGIGRRYANVVLKKADIDLTKRAGELSDEEVERVITIMAN PRQYKIPDWFLNRQKDVKDGKYGQVMSNYLDNKLREDLERLKKIRAHRGLRHYWGLRVRG QHTKTTGRRGRTVGVSKKKGSGSDTESDDSPPELEETATTTGLEGETTSKAKHSRSEKKA RKSLMRCGLKPLPGINRVTIRKSKNILFIISKPDVMKSPSSDTYVVFGEAKIEDLTQSAQ MQAAKKFETDEEIDETGIEPKDIELVMQQASVSKRKAVKSLRESDNDIVNAIMMGRVRTK TIKKASRVIIEKYYTRLTLDFHTNKRVCEEIAIIPSKKLRNKIAGFVTHLMKRIQQGAVR GISIKLQEEERERRDNYVPDVSAIEEVDPDTKEMLKILDFANIPGLQVTAPITNTMKWEY KEEHPFEKRRAEGEKIRKKYPDRVPVIVEKAPKARVGDLDKKKYLVPSDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGSLYQDYHEEDFFLYIAYSDESVYGMREVRIRKL CLNICVGESGDRLTRAAKVLEQLTGQQPVYSKARYTVRSFGIRRNEKIAVHCTVRGPKAE EILERGLKVREYELRKNNFSSTGNFGFGIQEHIDLGIKYDPNIGIYGMDFYVVLGRPGYN VAHKKRKTGVVGFRHKVTKDDSMKWFQQKYDGVILPGKMGVKFLEFVKPFCAVLPEISKP ERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVITASNRGTLMELGIS PVVTTGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMVITVGQAIVYVMTGMYGDPAD IGAGVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVN TGRGTEFEGAIIALFHLLATRTDKVRGLREAFYRQNLPNLMNLMATIFVFAIVIYFQGFR VDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYIISQMLAAK----------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------XXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX MVNVPKTRRTFCKGQKCKKHTIHKVTQYKTGKASLYAQGKRRYDRKQSGYGGQTKPIFHK KAKTTKKIVLRMECTSCKFRKQIAIKRCKHFELGGDKKRKGQMIQFMGRVIRSQRKGAGS VFRSHVKTRKGAAALRAVDFAERNGYIKGVVKDIIHDPGRGAPLCKVTFRDPYKYKQRTE TFLAAEGMYTGQFLYAGKKANLQIGNILPVGVMPEGTIVCCLEEKTGDRGRLARASGNYA TVIAHNPDTKRTRVKLPSGTKKVIPSANRAMVGIVAGGGRTDKPMLKAGRAYHKYKVKRN CWPKVRGVAMNPVEHPHGGGNHQHIGKPSTVRRDTSHGRKVGLIAARRTGRLRGKKK--- -AKRTKKVGIVGKYGTRYGASLRKTIKKLEISQHGKYTCTFCGKDAMKRKAVGIWHCKGC RKVVAGGAWVQSTTAAATVRSTVRRLREIKEMGRRPARCYRYCKNKPYPKSRFCRGVPDA KIRIFDLGRKKARVDEFPLCIHLVSDEYEQLSSEALEAGRICCNKYLVKNCGKEAFHIRI RVHPFHVLRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQPIMSVRAREQHKDSVI EALRRAKFKFPGRQKIHVSRKWGFTKWDRTVYEDMRRDGRLVPDGVTVQYRPNHGDLSRW KDAQRVTKILGRTGSQGQCTQVRVEFLDDSNRAIIRNVKGPVREGDILTLLESEREARRL RMTKGTSSFGKRHNKTHTLCRRCGRSSYHIQKKTCSQCAYPAAKCRSYNWSVKGKRRKTT GTGRMRHLKIVQRRFRNGFREGTVPKPRRK-IHSGSAAKDLDQWIEQLNECKQLSENQVK TLCDKAKEILSKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGRSPDTNYLFMGDYVDR GYYSVEAVSLLVGLKVRFPSRITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDSQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHTNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRC GNQXAIMELDDSLKYSYSSIQLTPR--EPHV---------MGAYKYIQELYRKKQTDVMR FLLRVRSWQYRQLSSIHRVSRPTRPDKARRLGYRAKQGICIYRCRVRRGGRKRPVPKGAT YGKPVNEGVNQLKFKRSHQSVAEERVGRKCGALRVLNSYWVAQDSTYKFYEVILVDPFHK AIRRNPDTQWLCKAVHKHRELRGLTSAGKKSRGLGKGHSYNKTTGGSVKASWKRRNSTSL RRKRGIAAGRLAEERKAWRKDHPFGFVAKPTKNPDDTLNLMLWECLIPGKKGTNWEGGYY KLKMIFKEDYPTTPPKCKFDPPIFHPNVYPSGTVCLSLLDEDKDWRPAVTIKQILIGIQD LLNDPNIRDPAQAEAYTVYCQNRSDYDKKVKEQAQQY-----XXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMQNEGGEFVDL YIPRKCSASNKIITAKDHASIQLNIAEVDVNTGRMTGSNKTYSLCGSLRRMGESDDCINR LAQRDGVIAKMPRGPKKHLKRLNAPKHWMLDKLGGTFAPKPSCGPHKTRECLPLMIFLRN RLKYALTYTEVNKIVMQRLIKVDGKVRTDKRYPTGFMDVVTIEKTNEQFRLIYDVKGRFV VHRITDQEAKYKLCKVKKISVAQKGVPYIVTHDGRTIRYPDPLVKVNDTIQLXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXX-SSSYDRAITIFSPDGHLFQVEYAQEAVKKGSTAVGVR GKDVVVLGVEKKAVAKLQEDRTVRKIALLDEHVAMAFAGLTADARILINRARIECQSHRL MVEDPVTLEYITRYIAQLKQKYTQSNGRRPFGLSALLVGFNGTPHLYQTDPSGTYHAWKA NAIGRSAKAVREFLEKHYTEEHVTEKETVKLALKALLEVVQSGGKNMEIAVMRRDQPLAM IDPSEIEKLIAEIEKEKEEEAEKKKQKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMAPQKKSKK AIESINSRLALVMKSGKYVLGYKQTLKTLRQGKAKLVIIANNTPPLRKSEIEYYAMLAKT GVHHYTGNNIDLGTSCGKYFRVTVLSITDPGDSDIIRSMPTEXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXMGDRYNIHSQLEHLQSKYIGTGHADTNKWEWM TNQHRDRHASYMGHFDMLNYFALVENEAKARVRFNLVEKMLQPCGAPPERPEDMKIELCA FSGYKIYPGHGKRMVKIDGRSFFFVNSKSEKSHLMKRNPRKINWTVLYRRKHKKGQQEET TKKRTRRNVKYTRAIQGATLSDIMAKRHQNPEVRKAQREQAIRAHKEKQKAKDKGAPRVG SKRMKLNISFPATGCQKMIEVHDEHMLRNFYDKRMATETSAECLGAEWKGYVVRITGGND RQGFPMKQGILTNTRVRLLLSRGMTCYRSRRSGERKRKSVRGCIVDANLSVLSLVIVKKG EQDIPGLTDRTIPRRLGPKRASKIRKLFNLAKEDDVRQYVVRRPLAATTKAPKIQRLVTP VVLQRKRHRLALKKRRAVKKREDAADYAKLLAQRMKEAKERKMERRRSASKSRKVKAKEL RGKKKDELETQLKNLKQELLTLRVNKVTGGAPTKLSKICFVRKSIARIYTVIHQTQKENL 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YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGEPTNDYVDTAVRHVLLRQ GVLGIKVKIMLPWDPTGKLGPKRPLPDHVSIVEPKEEIIPETPYSEQKGAKMSKRGRGGS SGGKFRISLALPVGAVINCADNTGAKNLFVIAVKGIKGRLNRMPAAGSGDMFVATIKKGK PELRKKVMPAVVVRQRKSIRRKDGVFIYFEDNGGVIVNNKGEMKGSAITGPVAKECADLW PRIASNASSIRKGKVQKVALGPQVADGENVFGVAHIFASFNDTFVHVTDLSGKETIARVT GGMKVKADRDEASPYAAMLAAQDVAEKCKTIGITALHIKLRATGGNKTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRLXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEGA VTLRTRKFMTNRLLSRKQMICDVLHPGRATVPKTEIREKLARMFKTTSDVIFCFGFKTKF GGGKTSGFALIYDSLDLAKKFEPKYRLARHGGRKQRKERKNRQKKVKGTAKAKIG-XXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXMGNMFASLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVGEAKDELSRMLAEDELRD AVLLVFANKQDLPNAMNAAEITDKLGLHALRNRNWYIQATCATSGDGLYEGLDWLSNQLK ASKMPLAKDLLHPSLKEETRRCKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRRKPHMVRINVLSDALRSICNAEKRGKRQVLLRPNSKV VVKFLSVMMKHGYISEFECIDDHRAGKIVVFLTGRLNKCGVISPRFDISIRDMEQWTNKL LPSRQFGLIVLTTSGGIMDHEEARRKHLGGKILGFFYMGRMHSHGKGISQSALPYRRSVP VWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGIAQVRFVTGNKILRILKAKGLAPD LPEDLYYLIKKAVSIRKHLERNRKDKDAKFRLILVESRIHRLARYYKLKKVLPGNWKYDS HTASALVAIAELPEIKVFGRWSTDDVQVSDISLTDYIAVKEKYAKYLPHSAGRYQMKRFR KAQCPIVERLVSSLMMHGRNNGKKLMTLRIVRHAFEIIHLLTGENPLQVLVNAIINGGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREAAFRNIKTIAECLSDELINAAK GSSNSYAIKKKDELERVAKSNRMTEQMTLRGTLKGHEGWVTQIATTPTNHDMLLSASRDK SLILWHLTRDTNYGVPKRSLRGHGHFVSDVVISSDGQFALSGSWDGTLRLWDLYKGTTTR RFVGHTKDVLSVAFSPDNRQIVSASRDKTVKLWNTLGICKYTIDDCHSDWVSCVRFSPSQ SNPIIVSCGWDKYVKVWNLTNCKLKTNHIGHSGYLNNVTVSPDGSLCASGGKDAQAMLWD LNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPTIKIWDLEGKIVVDELRLEFLSGT-- APQCISLAWSSDGQTLFAGYTDNLIRVWQVSMAARMREYKLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKQVEIDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKLARQFGCTFMETSAKAK INVNEIFYDLVRQINKRNPET--EVKP-ESEHINLKVQGQDNSVVHFKIKKNTPLRKLMT TYCDRAGLKMGVVRFMFDGNPVNEQDTPAQLEMEDTDVIEVFQQQTGG--AAPLNPKPFL NGLTGKPVMIKLKWGMEYKGYLVSVDGYMNLQLANTEEYIDGALTGNLGEVLIRCNNVLY VRGVEEDDEDGETREMSDAEGDDVPT--VGAGAMDLNTALQEVLKNALIHEGLARGLREC AKALDKRQALICVLAKNCDEPTYVRLVEALCAEHGIDLIKVDDNKKLGEWSGLCKIDQNG KARKIVGCSCVVVRDYGKESPAIDVMKSYLKHR-MTSIRKKLVIVGDGACGKTCLLIVFS KDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSI DSPDSLENIAEKWTPEVKHFCPKIPIILVGNKKDLRNDKQTIAELARQKQEPVKFDEGKL MADKMGCYAYLECSAKTKDGVREVFETATRSALQKSKKRKLKMDDVQTGEECVFVVDEIT TIIKESIETAIGGNAYQHNKVNQWTSNVVEQCLNHLTKLNKPFKYIVTCVIMQKNGAGLH TASSCFWDNSTDGSCTVRWENKTMYCIVSVFGLAIMFSASAKILKPQGETPDEFESSIST ALYELEMNSDLKAQLRELYITGAKEIDVAGKKAIIIFVPVPQLKNFQKIQTRLVRELEKK FSGKHVVFIAQRRILPKPTRKTKNKGKQKRPRSRTLMAVHDAILDDLCYPSEIVGKRIRI KLDGSRLIKIHLDKNQQTNIEHKLD-----------------------XXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSGGLDV LNLKEEDVVKFLAASTHLGSTNLDFQMEQYVYKRKPDGTYIINLRKTWEKLLLAARAIAA IEHPGDICVNSSRPWGQRAILKFAAHTGAVAVAGRFTPGTFTNQIQAAFREPRMLIVTDP RTDHQSIVEASYVNIPVIAFCNTDSIPRYVDIAIPCNNKGKNSIGLMWWVLAREVLRLRG SISREVPWDVMPDLYFYRDPEEAEKE---ENWGNDPVVSMAPV-VNEWS----------- -------MKFNKLISSSRRKQRNRHFNAPSHVRRKIMSASLSKELRQRYNVRSMPIRKDD EVQVVRGHYRGQH-GKVIQCYRKKFVIYVERIQRDKANGAQVNVGIHPSKVVINKLKLDK DRKSILDRRAKSRQMGKHTEESVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----KKKSAITEVVTRECTIHLHKKIHGI GFKRRAPRAITEIRKFAEKMMGTEDVRIDTRLNKHIWSQGVRNVPYRVRVRLARKRNEDE DSAHKLYTLVTFVQVAGFKGLQTKNVDSPGKNEFSINQKYRLLRKIGSGSFGDIYLGMNI ANGEEVAVKLESLKARHPQLLYESKLYKILQGGVGIPHIRWYGERDFNVLVMDLLGPSLE DLFNFCGRRFTMKTVLMLADQMIGRIEYVHNKNFIHRDIKPDNFLMGIGRHCNKVFLIDF GLAKKYRDNRSRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRGS LPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLR QLFRILFRTLNHQYDYTFDWTMLKQKAAAAMNKDKLAKRVGGKGTARRKKKVVHRTAAAD DKKLHGSLKKLSVNNIPGIEEVNMIKDDGTVIHFNNPKVQASLNANTFAITGHAETKSIG EMIPEILNQLGSSGFSQLQKLAGVTEEVD-EDDDVPDLVENFDEASKNEXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKKTGPKPELTEE QKNEIREAFDLFDSSGSGVIDAKELKVAMRALGFEPKKEEIKKMISDIDKDGSGTIDFND FLTIMTQKMSEKDSKEEILKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQEADRD GDGEINESEFLRIMKKTSLYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMALIVPEKFQHIL RVMNTNIDGRRKIMFAMTAIKGVGRRFSNVCLKKADIDLSKRAGELTDEEVERVVTIMGN PRQYKIPDWFLNRQKDVKDGKYSQVMSNSLDNKLREDLERLKKIRAHRGLRHYWGLRVRG QHTKTTGRRGRTVGVSKKK-SSSGTESDDDVPDLVK-IRTEGLGDDPVSKAKQSRAEKKA RKAMLKLGLKHIVGVNRVVIRKSKSILFVIPTPDVYKSPASDIYIVFGEAKIEDLSQQAQ VQAAERFKADEEVSDEGIPAKDIELVVQQAGVSRSKAIKALRANDNDIVNAIMXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKWQY KEEHPFEKRRAEGEKIRKKYPDRVPVIVEKAPKAHVRDLDKKKYLVPSDLTVGQFYFLIR KRIQLRPEDALFFFVNNVIPPTSATMGALYQEHHEEDFFLYIAYSDESVYGMRDIRIRKL CLNICVGESGDRLTRAAKVLEQLTGQQPVFSKARYTVRSFGIRRNEKIAVHCTVRGPKAE EILERGLKVREYELKKRNFSDTGNFGYGIQEHIDLGIKYDPGIGIFGMDFYVVLGRPGFN VSQKKHKRGVIGTRHKITKDESMKWFQQKYDGIILPGKMGIKFLEFVKPFCAVLPEIAKP ERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGIS PIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMVITIGQAIVYVMTGMYGEPAE IGAGVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATIN TGRGTEFEGAIIALFHLLATRSDKVRALREAFYRPNLPNLMNLLATILVFGVVIYFQGFR VDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAAKFSGNFFVNLLG VWADVGSGGPARSYPIGGLCYYLSPPETLGHVLEDPIHACLYIIFMLGSCAFFSKTWIEV SGSSAKDVAKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFMGAIG SGTGILLAVTIIYQYFEIFVKEQSD---MSTLLFQVERAFQKQPTVFLNKKKVLLLRYVK NVGLGFKTPREAIDGTYIDKKCPFTGNVNIRGRILSGYILKLKMQRTCVVRRDYLHYVRK YNRFEKRHKNLSVHLSPAFRDAAIGDIVTIGECRPLSKTVKFNVLKISKGSGNKKGFEKF XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRVIRCQRKGAGS VFRSHTKKRKGAAKLRPVDYAERNGYIKGVVKDIIHDPGRGAPLAKVTFRDPYRYKMRQQ TFIAAEGMYTGQFVYCGKKANLQIGNILPIGQMPEGTIVCCMEEKTGDRGRLARASGNYA IVISHNPD----------------------------------------------YKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGKASTVRRDTPHGRKVGLIAARRTGRIRGGKKDLS AXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRRPARCYRYCKNKPYPKSRFCRGVPDP KIRIYDLGRKKARCDDFPLCIHLVSNEYEQLSSEALEAGRICANKYLVKYCGKESFHLRM RVHPFHVLRINKMLSCAGADRLQTGMRGAFGKPQGLVARINIGQPLMSVRARDVHKDHVI EALRRAKFKFPGRQNIILSKKWGFTKWNREDYSTMKEDGLLIPDGVSVQYKPHHGPLQHW KNRQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMVDDKAAAKELDVWIEQLNECKQLTENQVK TLCEKAKEILSKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDR GYYSVETVTLLVALKVRYKERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDAQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHSNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRC GNQAAIMELDDALKYSFLQFDPAPRRGEPHVTRRTPDYFLMGAYKYIQELYRKKQTEVMK FLQRVRCWQFRQLTAIHRVTKPTRPDKARRLGYRAKQGYVIYRVRIRRGGRKRPVAKGAV FGKPVNQGVNQLKPARRHQTVAEERAGRKCGALRVLNSYWVSQDSTYKFYEVILVDPFHK AIRRDAKINWLCQPVHKHREMRGKTSVSRKSRGLGKGHKFTHTIGGSRSSCWKRNNREQM RRKRGIALARLAEERKAWRKDHPFGFVAKPIKNQDGTLNLMNWECAIPGKKNTIWDGGLY KMRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSLLDEEKDWRPAVTIKQLLLGIQD LLNDPNIKDPAQAEAYTIYCQNRAEYEKRVKKQAEQFRDPS-FKSSKMMTYINYRMRCTL QDGRTFIGTYKAFDKHMNLILGDCDEFRRIKPKSSKGREEKRVLGLVLLRGENLVSMTVE GPPPSDEGMPRVPMPGSS-GPGFGRASGRGTGGPGGLQGPVRGVGGPSQQMMAPGPQMGR GGPP---PTFKCVLVGDGGVGKTTFVKRHITGEFEKKYVATLGVEVHPLVFYTNRGPIRF NVWDTAGQEKFGGLRDGYYIKGQCAIIMFDVTSRVTHKNVPNWHRDLVRVCENIPMVLCG NKVDIKDRKVKAKSIVFHRKKNLQYYDVSAKSNYNFEKPFLWLAKKLIGDANLEFTQMPA MPPPEVHMDPALIAKYENEIAQAQQTVLPDDDDEFSEGIRQYYVSKIEDLQLTVTDKTQN LRRLEAQRNELNAKVRMLREELQLLQEQGSYVGEVVKPMDKKKVLVKVHPEGKFVVDLDK NIDMNDVTPNCRVALRNDSYALHKILPNKVDPLVSLMMVEKVPDSTYENVGGLDKQIKEI KEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ KFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRLEGGSGGDSEVQRTMLELLNQLD GFEPKQNIKVIMATNRIDILDPALLRPGRIDRKIEFPAPSEIARADILRIHSRKMNLTRG INLRKIAEMMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFELAVAKIMQKDHEKNMSI KKLWKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGD CSDLDRQIEQLRRCEIIKETEVKSLCAKAREILAEESNVQRVDSPVTVCGDIHGQFYDLK ELFKVGGDVPDTNYLFLGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQV YGFYDECLRKYGSITVWRYCTEIFDYLSLSAVIDGKIFCVHGGLSPSINTLDQIRAIDRK QEVPHDGPMCDLLWSDPEDTQGWGVSPRGAGYLFGSDVVSQFNSANNIDLICRAHQLVME GYKWHFNETVLTVWSAPNYCYRCGNVAAILELDENLQRDFTIFEAAPQENRGKPVPDYFL VRLPPEVNRILYIRNLPYKITGEEMYDIFGKYGPIRQIRVGNTPETRGTAFVVYEDIFDA KNACDHLSGFNVCNRYLVVLYFQSNKAFKKVDTDKKKVEIDRMKNKYGLST----MSIGV PIKVLHEAEGHIITCETTNGEVYRGKLIEAEDNMNCQMSTITVTYRDGRVAQLENVYIRG SKIRFLILPDMLKNAPMFKKVGTGRGKSAILRAAARGRGRGDRGGGRGGMQNEAGEHVDM YIPRKCSGTSRIIGSKDHASIQINIAEVDETTGRMTGSYKTYAISGTVRAMGESDDIIFH LAKKDGI---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGTKDDEY DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTA GQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADNNIVIMLVGNKCDL RHLRAVPTEEARAFAEKNNLSFIETSALDSTNVEAAFQNILTEIYRIVSQK--------- -----------------------TARYDRAITIFSPDGHLFQVEYAQEAVKKGSTAVGVR GKDIVVLGVEKKAVAKLQEDRTVRKIALLDDHVAMAFAGLTADARILINRARIECQSHKL TVEDPVTLEYITRYIATLKQKYTQSNGRRPFGLSALIVGFDGTPHLYQTDPSGTYHEWKA NAIGRSAKVVREYLEKAYNEEAVNDKDSIKLALKALLEVVQSGGKFMEVAVMKKGEPLKM IEQSVIEEYIAEIEKEKEEEAEKKKKKNSGRDGDKKDDK-KTKKYEPPVPTRVGKRKKKM KGPDAANKLPQVTPHTRCRLKLLKLERIKDYLLLEEEFIKNQERLKPQEEKTEEERSRVD DLRGTPMSVGSLEEIIDDNHAIVSTAVGSEHYVSILSFVDKDQLEPGCSVLLNHKVHAVV GVLSDDTDPMVTVMKLDKAPQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIRPPK GVILYGQPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPS IVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPA LIRPGRIDRKIEFPLPDEKTKRKIFTIHTSRMTLSEDVNLEDYIMAKDDLSGADVKAICT EAGLLALRERRMKVTNEDFKKAKENVLYRKSEGTPEGLYLKKAPYSPFQNSNTAEYAVAR ADDLLNWARKSSLWPMTFGLACCAVEMMHFAAPRYDMDRFGVVFRASPRQSDCIIVAGTL TNKMAPAFRKVYDQMPEPRWVISMGSCANGGGYYHYSYSVVRGCDRVVPVDIYVPGCPPT AEALLYGVLQLQKKIKRMKGMQVWYRKDDFYLRYYVGHRGKFGHEFLEFEFRPDGKLRYA NNSNYKNDTMIRKEAFVHKAVLEEIKRIIQDAEIMQEDDSSWPPPDRVGRQELEIVIGDE HISFTTSKIGSLVDVHQSKDPEGLRTFYYLVQDLKCLVFSLIGLHFKIKPI--------- -XESINSRLALVMKSGKYHLGYKQTLNNLRQGKAKLVIIANNTPPLKKSEIEYYAMLAKT GVHHYNGNNIDLGTACGKYFRVTCLTITDPGDSDIIRSMPT------------------- -------NHFVEEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGF LCVFAVNNSKSFEDINQYREQIKRVKDAEEVPMVLVGNKVDLPTRTVDTKQAKTMADNYT IPYVETSAKTRQGVDDAFYTLVREIRKYMGDRYNIHSQLEHLQSKYIGTGHADTNKWEWL TNQHRDSLASYMGHIDMLSYFALAENESKARVRFNLMEKMLQPCGPPPARPEDXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAKKKGPKVSEKV FFDITIGGKDVGRIVIGLFGKTVPKTVNNFKSLAEGIETYEGSKFHRVIKDFMIQGGDFT RGDGTGGQSIYFADENFKLKHYGAGWLSMANAGKNTNGSQFFITTKITTWLDGKHVVFGK VLEGMKVVRMIEDTKTE-DRPVKDVVIKKSGSLKVDTPFAVDKE----XXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------DDIIYGDCSGPNAMYVKLV SSDGHEFIVKREHALTSGTIKAMLSGPGQFAENDTNEINFREIPSHVLHKVCMYFNYKVR YTNSSTEIPEFPIAPEIALELLMAANFLDC-KKYTLDEVKQHKNSKSLWLVIHDKVYDVT KFMEEHPGGEEVLLENGGKYGTEPFEDVGHSSDARELMKDFLIGELVEPDRGGLSSWLIP LAIAIAAALVYRFVMSYMLQHLNNGWQVDQAILSEEDRVVIIRFGHDWDPTCMVMDETLY KSAEKVKNFAVIYLLDISHVPDFNKMYELYDPCTIMFFYRNKHIMIDLGTGNNNKINWAM EDEQEFIDIVETVYRGARKGRGLVVSPKDYSTKYRYKKLQRQLEFLEVQEEYIKDEQKNL KKEYLHAQEEVKRIQSVPLVIGQFLEAVDQNTGIVGSTTGSNYYVRILSTIDRELLKPGA SVALHKHSNALVDVLPPEADSSITMLGSDEKPDVQYSDIGGMDIQKQEVREAVELPLTHF QLYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVR DVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTVNVKVI MATNRADTLDPALLRPGRLDRKIEFPMPDRRQKRLIFSTITGKMNLSEEVDLEDFVSRPD KISGADINAICQEAGMHAVRENRYVVLAKDFEKGYKNNVKKDETELEFYKSKPPLTLQMV RDRVLLVLKLYDKINPEKLTVDSHFMTDLGLDSLDHVEVVMAMEDEFGFEIPDADAERLL RPADIVQYIADKEDISRRVMS-ENELKNVEFETSEDVEVVPTFDSMGLRDELIRGIYAYG FEKPSAIQQRAIRPIVKGRDVIAQAQSGTGKTATFSISILQCLDTQVRETQALCLAPTRE LATQIQKVILALGDYMSVQCHSCIGGTSVGEDIRKLDYGQHVVAGTPGRVFDMIRRRNLR TRSIKMLILDEADEMLNKGFKEQIYDVYRYLPPATQVILISATLPHEILEMTSKFMTDPI RILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIF-------------- ------------------------------------------------------------ ------------------------------------------------------VPLRRP FDPAAHDLDPSFRLTRFTDLKGGCKVPQEVLLKLLEGLQDNEGGDPGQFGYMSSLPRVGI GMDACVLPLRHGGLSLVQTTDFFYPLVDDPYMMGKIACANVLSDLYAMGVTECDNMLMLL GVSNKMTDKERDVVVPLMIRGFKFLAEEAGTSVNGGQTVLNPWMTVGGVATTVCQQNEFI MPDNASIGDVLVLTKPLGTQVAVNAFQWLDQPERWNRIKLVVTEDDVRKAYQRAMFSMAR LNRTASRLMHKYNAHGATDITGFGLLGHANNLAKIQKKEVSFVIHNLPVIAKMAAVSKAC GNMFGLLQGNSAETSGGLLIALPREQGAAFCKDIDKQEGYQAWIIGIVEKGNRTARIIDK PRVIEVPAKEKEFVFSLLSGIDCYFISVDANAEECFFDRVTSGTKLSLMFEVAEGGFLDI GVKIIGPDNKSVYSEERESNGKYTFSAHMDGIYKYCFSNKMSTMTPKIVMFSMDIGEKPK AHHNKLEEMINELSTSLTMVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMT LGQVYYLKRFFEVRRVV-AATLQPYLQAARHTLTAAMCLENFSSQVVERHNKPEVEVMTS KELLLTPVVISRNEKEKILIEGSINSVRISIAIKQADELEKILCKKFTRFMMMRADNFVI LRRKPIEGYDISFLITNFHTEQMYKHKLVDFIIHFMEEIDKEISELKLAVNARARISAEE FLKRFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXTAPFDARFPNQNQSRNCWQNYVDFHRCQKIEEYE PCNYFRDTFRSLCPNAWVEKWDDERENGSFAGKIMPDYLGDDQRKTKETDEKEKPIQALD EGDIALLKTYGAGMYSRTIKSVEEDIQATLKRVNELAGIKESDTGLAPPALWDLAADKQT LQSEQPLQVARCTKIINADSDDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNK YQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVEVPLLHPERFVKLGI EPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMART KKACIIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDT LDPALMRPGRLDRKVEFGLPDLEGRTHIFKIHARSMSVEKDIRYELLARLCPNSTGAEIR SVCTEAGMFAIRARRKIATEKDFREAINKVIKAYAKFSATPRYMTYNMPKEKTHINIVVI GHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITI DIALWKFETTKYMVTIIDAPGHRDFIKNMITGTSQADCAVLIVACGTGEFEAGISKDGQT REHALLAFTLGVKQMICGFNKMDNA--GYKEDRYIEIKSEVSKYLKKVGYALDGVPFIPI SGWHGDNMINMTWWKGCEIFKCKTLLEALDAIAPPTRPTDKPLRLPLQDVYKIGGIGTVP VGRVETGILKPGTVVTFAPAAITTEVKSVEMHHSALTEALPGDNVGFNVKNVSVKEIKRG NVAGDSKNDPPKAANTFYAQVIIMNHPGQIHNGYCPVLDCHTAHIACKFTEIAQKIDRRS GKTLEENPKSIKSGDAAMVTLTPSKPMCVEPFAEYPPLGRFACRDMKQTVGVGVIKSVAK KE-KEAKATKSAQKAEIDQLRQECEQLKNQIREARKAAADTTLSQATQNVEPVGRIQMRT RRTLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAP SGSFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDNQIVTSSGDMTCA LWDIETGQQTTSFTGHTGDVMSLSLAPDFKTFVSGACDASAKLWDIRDGMCKQTFSGHES DINAITFFPSGNAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLMLG GYDDFNCNVWDTLKMDRAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKIWNMSYAYLF KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES FRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLEARR EVKKEEGEAFAREHGLIFMETSAKTAANVEEAFINTAKEIYQKIQDGVFDINNEANGIKI GPQHSPSNPSGGGGGAQGGG------ELGDVTVHNIKQLKRLNQVIFPVSYNDKFYKDVL ENGELAKLAYFNDIVVGAVCCRVDTSDNQRRLYIMTLGCLGPYRRYGVGSIMLKHVLKIC KEDGNLDNVFLHVQVNNTGAIDFYKKFGFEIVEKKENYYKKIDPADAYVLQKTFRQMPRQ INEIKEFLLTARRKDAKSVKIKKNMKFKVRCSRFLYTLVIQDLEKAEKLKQSLPPGLAVQ DLD------DVLVEAVQTVLTKKRKFTETVELQIALKNYDPQKDKRFSGTVKLRHIPRPK MKVCVLGDQQHIDEATANNLACMDVEALKKLNKNKKLVKKLAKKYDAFLASDSLIKQIPR ILGPGLNKAGKFPAILTHNESMINKVDEVKATIKFQMKKVLCLSVAIGHVNMQQDELVAN ILLGINFLVSLLKKNWQNVRALYVKSSMGPSQRVYMADADKLNIDSIIARLLEVRGSRPG KNVQLTEAEIRGLCQKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLNAGRPVTPPRGQAKNK KK-MFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEIVGTNVSTT YITCPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPF ICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDEL PAEFKLYLPVQKK-----IVNLTDPFEL---VHVRIQQRNGRKTLTTVQGLSDEYDLKKI VKSCKKAFACNGTVVEHPEYGEVIQLQGDQRSNIVDWLLETKIKTQIKVHGFSALFNFQS LLSVVLLLICTCAYVRSIAPSIVDRNKQGFLGIFWKCARIGERKSPWVAVCCVAMALNIL FI---------------------------------------------------------- ---------------------EEMVEFGSGLKGMALNLERDNVGVVVFGNDKLIKEGDIV KRTGAIVDVPVGEELLGRVVDALGNVIDGKEAVN-CKRARVGIKAPGIIPRTSVKEPMQT GIKAVDSL------------------------------KRFNDSADEKKKLYCIYVAIGQ KRSTVAQLVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCAMGEYFRDNGKHALIIY DDLSKQAVAYRQMSL--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MESLYKIPYNVLEVPNLKLKKPSWVKWPSPMFMYALILSSYFIVTGGIIYDVIVEPPSIG STTDERGNSKPVAFMPYRVNGQYIMEGLASSFLFTIGGLGFVILDRTNQPALPKLNRILL LAVGFICILISFFMLRVFMRMKLPMGKVKRSRKPPPDGWELIEPTLDELDQKMREVETDP HEGKRKVEALWPIFKIHHQRSRYIFDLFYKRRAISRDLYDYCLKENIADKNLIAKWKKQG YENLCCLRCIQTRDTNFGTNCICRVPKAKLEEGKVVECVHCGCRGCSGEYARVVKMLGNG RLEAMCFDGEKRLCHIRGKLRKKVWISQGDFILVGLRDFQDTKADVILKYSADEGRNLKS YGELPENVIIKDDG-SNIEFDEVDDILVRFLMKLSHETVTIELKNGTQVHGTITGVDVSM NTHLKTVKMTMKNRDPVQLDSLSIRGNNIRYYILPDSLPLDTLLIDDAPKARFKRXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPIVIDARGHLMG RLAALVSKTILQGQRVVVVRCEGINISGSFYRNKLKYLEYLRKRCNVNPSRGPFHFRAPS RVFWKTVRGMLPHKLHRGKDAMDRLKVFEGIPPPYDKKKRMVVPSALKVLRLNPRRKYCV LGRLSHEVGWKYQNVIRTLEQKRKNKSTAFHIKKKQNAALMEKAKKLPAQQKLLAEHGYA GDATKGAKIFKQRCAQCHNVEKGGKHQTGPNLHGLWGRKTGQAEGFSYTAANQKKGITWG QDTLWVYLADPKKYIPGTKMVFAGLKKKQERADLIAYLEKATQIFVERTLAIIKPDAVSE EIEDIILRSGFAILQKRRVQLTPEQASDFYAEHFGKLFFPSLVAYISSGPIVALVLGKEN SINHWRELIGPTNTLKARQTHPDSLRAIYGTDDQRNAFHGSDSQSSAEREIRFFFPDAIM EPVADGQTARDYLAKSVNPTLLKGLTELGKQKPLDPVTWLADWLLENNPNKPKV------ ------------------------------------------------------------ ------------------------------------------------YELKLMDLDQEH LGIPDQEYKCIVKLPAAEFQRICRDLSQIGDTVVICCTKEGIKFSCSGDLGTGNIKLAQS SXADKEEDAVIIDMKEPLVLNFSLRYLNFFTKATPLAQQITLSLAPNIPLVVEYKIADLG HIRYYLAPKLDDEEN-KSFSAYNTSRRAITGKVVAVIGAVVDVQFEDQLPPILNALEVKG RSPRLVLEVAQHLGESTVRTIAMDGTEGLVRGNECVDVGSPIRIPVGPETLGRIINVIGE PIDERGPIPTDRRAAIHADAPEFVEMSVQQEVLETGIKVVDLLAPYAKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVINLKDKSSKVSLVYG QMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIA ELGIYPAVDPLDSVSRILDPNVVGMEHYNIARGVQKILQDYRSLQDIIAILGMDELSEED KLTVSRARKIQRFLSQPFQVAEVFTGSAGKLVPLADTIKGFNQILKGECDHLPESAFYMV GDIAEVFEKAERIA---MLMPKKNRVAIYENLFKEGVMTAKKDFTLAKHSEVEVPNLHVI KACTSLKSRGYVKEQFAWRHYYWYLTNEGIQYLRDFLHLPPEIVPATLKRTEMAADRAGY RRGPGADKKGDVGAGTAMGDNNSKLTPEDINDLK-ELQYTEKEIKQWYKNFQKECPSGHI TKKEFKQLYGSFFPKGDSTKFAEHVFRTYDSDGDEKLNFREFIGALSITTKGSMEQKLNW AFSLYDLDGNGFISKDEMLEIFKALYKMFQNDKKMKDDLETPEKRLDHVFEKMDLNKDGQ ISKEEFIEGVKNDDFMMRVLKSD-MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNL TGLNEQVPHYRQALDMILDLEPD---EDNPNQSDLIEQAAEMLYGLIHARYIMTNRGIAQ MVEKWQNGDFGYCPRVYCENAPMLPIGLSDVPGEAMVKLYCPKCQDVYNPKSSRHHHTDG AYFGTGFPHMLFMVHPEYRPKRP------------------------------------- MTNTKGYRRGTRYMFSRKFRHRGAIPLSTYMKVYRRGDIVDIKGNGAVQKGLPHKIYHGR TGRVYNVTQHAVGVIVNKRVRGKILPKRINVRIEHVRHSNCRLDFLNRVKRNEILRKEAV EKVTLKRQAVQPKEAHFVRTKNNKPEILQPIPYEFIA----NYVQVSPDDPSMKFKDITD RAAQSVFWTELAKGFGITLAHIFKEPATINYPFEKGPLSPRFRGEHALRRYASGEERCIA CKLCEAICPAQAITIEAEPRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEF STETHEELLYNKEKLLDNGDRWEVEIAANIQADHLYR------------------DKEQQ EAIEKIDEVQNEIDRLNEQASEEILRVEQKYNKLRQPFYTRRADLIGKIPNFWVTAFVNH PQVSALLTEQDEDALQNLQKVEVQEFEDIKSGYRINFVFDKNPFFTNDTISKEFHLNSSK STPIKWQPGQDLTKRPRKRNHDDQESFFCWFTDHSDAGADELGEVIKDDIWPNPLQYYLA SEIEEEGPDEEGIDEEDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXATQGKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQT VCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNHDTFGRAKTWVKELQRQ ASPNIVIALAGNKADLRMVEYEEAQAYAEENSLLFMETSAKTAMNVNDLFLAIAKKLPKN EEGVTLNGDDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFLSRSEYDRGVNLF SPEGRIFQVEYAIEAIKLGSTAIGIQTNEGVVLAVEKRITSPLIEPSSIEKIYEVDGHIG CAMSGLIADSRTMIDKARVEAQNHWFTYNEKMSVESCTQAVSNLALAFGDDNPEAGALSR PFGVALLFAGIDDKGPQLFHMDPSGTFIQYDAKAIGSAAEGAQQSLQEVYHKSMTLKEAC KQAMTILKQVMEEKLNETNVEMATVTPNRNFHMFSKGEIEDLIKDIAQKTWEVANDVENI SGVDEIFRYSHKQQQDILTAKPWEKDPHYFKYIRVSALALLKMVMHSRSGGNLEVMGMLL GKVDGNTMNVMDSFALPVEGTETRVNAQAQAYEYMAAYMDTAKMVNRLENVIGWYHSHPG YGCWLSGIDVNTQMLNQQFQEPFVAIVVDPVRTISAGKVNLGAFRTYPKGYKPPDEPPSE YQSIPLSKIEDFGVHCKQYYSLEVSYFKSSLDSRLLESLWNKYWMNTLSSSTLLTNSEYT TRQISDLAEKLEQSESQVGRGVFMDKKSEDKLTKATRDGCKMTIEAMHGLMTQVIKDKLF NKL-----------------------AVPCENNARFFFVSIEGPSESPYENGVFKLELFL PEDYPMSPPKVHFRTKIYHPNIDKHGRICLDILKDKWSPALQIRTVLLSIQALLGAPNPD DPLANDVAKAWKDNECCAIMTAKEWTKKHADVENELLDYEE-EDQETKDVKGTYVSIHSS GFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILSMDVLCQAKSGMGKTAVFVLATLQ QLEAVDGQVSTLVLCHTRELAFQISKEYERFSKYNNNVKIAVFFGGLPLKRDEDVLKKNC PHIVVGTPGRILALAKTLSLKNIKHFILDECDKMLEQLDMRSDVQEIFRMTPHEKQVMMF SATLSKDIRPVCKKFMQD------------------------------------------ -----------RAQSISEMLEQKGWPSTFIAGNQDQKDRLIAMGKLKKFECRILVSTDLT SRGIDSDKVDLVINFDIPADHETYLHRVGRAGRFGSYGAAISLPAEGNELKEPPGYGDLG KSSRDLFGKGYNFGHYKLECKTKSNNGIEFTTSGSSNAETGKISGSLETKYKWKDYGLSF TEKWTTENVLGTQVTIEDQLAKGLKLSFDTSFAPHSGKKNGTIKTAYKMDYLNLACDVDF DFAGPTIHGAAVLGYHGWLAGYQMSFDKSKLTKNNFAVGYSGEDFTLHTSVNDSSEFAGS IHQRVSKELETSVNLSWTAGTNTTRFGLASKYDLDKDSSVRAKVSNNGQIGLGYAQKIRD GVTLTLSTMIDAKNINAGGHKVGLGLEFDA-SGREKALTDYRKKLLEHKELEARLKEMRE QLRDLTKQYDKSENDLKALQSVGQIVGEVLKQLTEDKFIVKATNGPRYVVGCRRQIDKAK LKAGTRVALDMTTLTIMRYLPREVDPLVYKMSAEDPGNINYSEIGGLSEQIRELREVIEL PLLNPELFQRVGITPPKGCLLYGPPGTGKTLLARAVASQVEANFLKVVSSAIVDKYIGES ARLIREMFNYARDHQPCIIFMDEIDAIRRFSEGTSADREIQRTLMELLNQMDGFDSLGQV KMIMATNRPDTLDPALLRPGRLDRKIEISLPNEQARLEIIKIHAQPIAKHGEIDWEAVVK LSEEFNGADLRNVCTEAGMFAIRAERDYVIEEDFMKAVRKVSDNKKLESKLDYKPIMGES VIAVLRKFYDEYMNNTSKKLKVIDSYLFYVLITGVIQFVYCLLVGTFPFNSFLSGFISCV CSFVIGVCLRVQVNPQNKNDFVGISPERAFADFIFAHVILHLVVINFIG-----SQLLPL ELVDKCIGSKIHIIMKNDKEIIGTLLGFDDYVNMVLEDVTEFESTPEGRRITKLEKILLN GNNITMLVPGGEGPEVIDHYENPRNVGSLDKKDKNVGTGLVGAPACGDVMKLQIQVDDNG QIVDAKFKTFGCGSAIASSSLATEWIKGKSVDEAGMIKNSDIAKELSLPPVKLHCSMLAE DAIKAALKDYKVKKDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXMGKFLKPGKVVLVLGGRYAGRKAVIVKNNDDGTQDKPFSHALVA GIDRYPRKVTKRMGKKKLKQRSKVKAFLKVYNFNHLMPTRYSVIPLDKKTVNKDVFRDPV LKKKATREVKSLFEERYKSGKNKWFFQKLRFXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMVSKQVIRTANAKHSKNVNIRGQVPKSLKP TEEGYPVGPWVIGLFIFVVCGSALFEILQHVRFIKVKSWTAVATWRWVANDENCGICRMP FDGCCADCKLPGDDCPLVWGQCSHCFHIHCIVKWLNSQQVHQLCPMCRRDWKFKEMIRFI LIQNRAGKTRLAKWYMHFDDEEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIVYRRYAGL YFCICVDVQDNNLVYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYSVVDEMFLAGEIRE TSQTKVLKQLLML----EPTIFDKILDGSIPADIIYKDDKCIAFRDVQPQAPKHFLVIPR KKIPMLSDDAPLLGHLMLVAKKVAAQENGYRLVINNGPDGSQSVYHLHIHVLGGRQMTWP PMGGFFSMFAGLWGSKERRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVQYKN IKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSMDRDRIGISKSELMSMLEEEELKKSI LVVLANKSDLQGCMSASEVANALGLSGIKNRKYQIFKTSATKGEGLDESMDWLTNAITQQ K----------------------------------------------------------- ----RTYAADGRFTFTSHSSGEHTLCLHSNSSAWFGSGQLRVHLDIQVGEHANDYQQIAA KDKLTELQLRVRQLLDQVEQITKEQNYQRFREERFRITSESTNQRVLWWSIAQTIVLLLT GFWQMKHLKSFFEAKKLVMFYHVSLEHEILLHPRYFGPNLLNVVKQKLFTEVEGTCTGKY GFVIAVTTIDNIGAGLIMPGRGLVLYPVKYKAIVFRPFKGEVLDAVVTQVNKVGLFTEIG PLSCFISKHSIPPDMEYDPNSNPPCYKTKDEEVVIQEDDEIRLKIVGTRVDANDIFAIGS LMDDYLGLVSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMAKKTY DLLFKLLLIGDSGVGKTCLLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTA GQERFHTITTSYYRGAMGIMLVYDITSAKTFENISKWLRNIEEHANEDVEKMILGNKCDM EDKRQVPKERGTTIAREHNIPFLETSAKLNVNVEKGFLDLAEAILRK------------- ------------------------------------------------------------ ---------------------------------KQKRKEKAGKWDVPLPKVKGVSENEVF KVVKTGKTRRKAWKRMVLKATFVGDGFTRKPPKFERFIRPMALRYKKAHVTHPELKAT-- ------------------------------------------------------------ ----------RPLISVYTEKNEPTGSNVTLPAVFRAPIRPDIVNFIHFQMKNNSRQPYAV SEKAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRR INVTQRRYALCSSIAATGVPALVMSKGHKIEGTPEVPLVISDKVEEIKKTKEAVTVLRKF GAWADIEKVYKSKRFRAGKGKMRNRRRIQRRGPLIIYNKDNGITKAFRNIPGITLLCVDH LNVLKIAPGGHVGRFCIWTESAFRKLDSIYGTWTKPSRTKSHYNLPMPKMTNTDLSRLLK SDEIQSVLRKPKKTIKRRVLKKNPLKNVRVMMKLNPYASVAKRSAINKKKKE-------- ------------------SGEQELATKMLQIQSKRFYLDVKQNKRGRFIKIAEVGAGGKK SRLLLAMSTAAEFRDHLTDLGTFYAKLGPHSPENIPEDGKLKSETMRKDNRRYYLDLKEN QRGRFLRVSPRTHQRNQIAIPAQGLIEFRDALTDLLLDFGTDDHEGSTQLPESRSMRVEN KMFYFDVGMNQRGVFMRISETNFRTAITIPEKSWGKFRDIMSDFIDKEERKLRDAQMRAT INQKLIETGEREKLKELLRTRLIECGWRDQLKAYCKEVVRQKGLEHVTVDSLVAEITPKG RALVPDQVKKELLQRIRSFLAQQSDMNIRNAVPEDLMNMQHCNLLCLPENYQMKYYFYHG LSWPQLSYVAEDEDGKIVGYVLAKMEEDPEEK-PHGHITSLAVKRSHRRLGLAQKLMDQA SRSMVESFNAEYVSLHVRKSNRAALHLYTSTLRFKISDTEPKYYADGEDAYAMKRDLNHL RDDIMSHTILLVQPCKRPESRTYSDYESVNECLEGVCKIYEEHLKRMNPNSPSITYDISQ LFDFIDQLADISCIVFQKSSATYVPHNKDWIKERIYILLRKQAGQMTEQVEEKKEETKTR --HTYPLIRRSDMPEEMRTEAMELCVTACEKFASNNENAAKMIKESMDKKFGASWHVVVG EAFGFEITYEIKNMLYMFFAGTTAISVWKCSXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXMQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLG LWDTAGQEDYDRLRPLSYPQTDVFLICFSLISPASFENVRAKWYPEVS------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------VDSDRDYTYDEMLQRIYDTMREKNPEIVAGEKKKLIMK PPQVMRVGTKKTSFANFTEICKLLHRQPKHLLAFLLAELGTSGSIDGNNQLIIKGRFQPK QIENVLRSYIKEYVTCHTCRSHETILQKDTRLFFLQCEICGSRCSVATIKSGFQAITGKR AAARNKT-FDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVSRPDGK DYSIHRLILGTHTSDEQNHLLIASVQLPNDNAQFDATHYDSEKGEFGGFGSVSGKIEIEI KINHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPNGDCQPELRLKGHQKE GYGLSWNPNLNGNLLSASDDHTICLWDINANPKEAKVIEAQTIFTGHTSVVEDVSWHLLH ESLFGSVADDQKLMIWDTRSNNTNKPSHTVDAHTAEVNCLSFNPYSEFILATGSADKTVA LWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQSAEDA EDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEEPDTPAS ELEMPLPSRARVYADVNTHRPREYWDYESHVVEWGQQDDYQIVRKLGRGKYSEVFEAINV TNNEKCVIKILKPVKKKKIKREIKILENLRGGTNIISLQAVVKDPVSRTPALIFEHVNNT DFKQLYQTLTDYDIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLA EFYHPGQEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPFFHGHDNY DQLVRIAKVLGTEELYEYIEKYQIDMDARFNDILGRHSRKRWERFVHSDNQHLVSPEALD FLDKLLRYDHNDRLTAREAMEHSYFYPIVKEXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXMEFMLLFSRQGKLRLQKWYVPHNDKLKKKITRELITTILARKPKMCSF LEWRDLKIVYKRYASLYFCCAIEAEDNELLTLEVIHRYVELLDKYFGSVCELDIIFNFEK AYFMLDELLLGGEVQETSKKNVLKAIAAQDLLQEEEPRSILEEMGL-MSKAHPPELKRYM DKRLSLRLNGNRNIVGVLRGFDPFMNIVMDECLEEKKNGERVQIGMVVCRGNSIVLLESH ERI---------KLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTI RLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERGSDVIIM LVGNKTDLADKRQVSTDEGEKKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMEQTDP KKMIEVKLKDTPAEPVSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- -----AAIPLLKTKAGPRDGDLWVERLKEEYLSLIAYVNTNKAADNDWFRLESNKEGTRW FGKCWYIHELLKYEFDIEFDIPVTYPATAPEIAIPELDGKTAKMYRGGKICLTDHFKPLW ARNVPKFGIAHAMALGLGPWLAVEIPDLISRSLVKHK-----FEFLDDVRRMNKRQLYYQ ILNFAMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFFRGDLLLLTNYEEEPVRVGD IVVFKVEGRDIPIVHRVLKVHEKENGDVKFLR--DNNSVDDRGLYAPGQVWLEKKDVVGR AKGFLPYVGTVTILMNDYPKFKYFILATLGIFVLIHREMSTMNPEYDYLFKLLLIGDSGV GKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYR GAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEY ADQLGIPFLETSAKNATNVEQAFMTMAAEIKNRMGPVTTSPNVKINSSTPVKQNSGGCCE ESLGEEVLRMSTDEVISRTRLLDNEIKIMKSEIMRISHELQAQKEKIKENTEKIKVNKTL PYLVSNVIELLDMDPQDE-EEDGANVDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKL EPGDLVGVNKDSYLILETLPAEYDSRVKAMEVDERPTEQYNDVGGLDKQIQELIEAVVLP MTHKDRFKALGIEPPKGVLLYGPPGTGKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGA KLVRDAFSLAKEKAPAIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFAPNSD IKVIAATNRVDILDPALLRSGRLDRKIEFPHPNEEARARILQIHSRKMNVSSDVNFEELS RTTDDFNGAMCKAVCVEAGMIALRRGATELTHEDYVEAIMEVQSKKKANLQYYAKDAADQ NFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRQDKRVKLQIWD TAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWCTQIKTYSWDNAQVVLVGNKC DLEDERVVSTERGKQLADQLGLEFFETSAKENINVKAVFERLVDIICDKMSESLDSDPTK GTRLTENPQPQNAGCQC------------------------------------------- ------------------------------------------------------------ -----------GPSVLAEDYLDIMGQPINPFSRIYPEEMIQTGISAIDGMNSIARGQKIP IFSANGLPHNEIAAQICRQGGLVKLPTKDVMDTSDDNFAIVFAAMGVNMEIARFFKQDFE ENGSMENVCLFLNLANDPTIERIITPRIALTTAEFLAYQCEKHVLVILTDMSSYAEALRE VSAAREEVPGRRGFPGYMYTDLATIYERAGRVQGRNGSITQIPILTMPNDDITHPIPDLT GYITEGQIYVERQLHNRQIYPPINVLPSLSRLMKSAIGEGMTREDHADVSNQLYACYAIG KDVQAMKAVVGEEALTPDDLLYLEFLTKFEKNFIAQGHYENRTIFETLDIGWQLLRIFPK EMLKRIPEKTLKKYYPRDS-GPGFVGIKFCQECNNMLYPKEDKENRVLYYACRNCDFQMP ADNPCIYVNKIQHDVDEITQIVADVIADPTLPRTEDHPCPRCGHKEAVFFQSHSSKAEEG MRLYYVCTHPKCTHRWTEKPAYKVADIGLAEMGRKALEIAENEMPGLMMMRRMYGPKKIL KGARIAGCLHMTVQTAVLIETLTELGAEVQWSSCNIFSTQDHAAAAIAKTGVPVYAWKGE TDEEYLWCIEQTLIFKDGKPLNMILDDGGDLTNLVHEKYPQYLEGIKGISEETTTGVHNL YKMMADKKLKVPCINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGKVAFVGGYGDV GKGCAQALRSFGARVLVAEIDPINALQAAMEGYEVTTIDEAVKEARIFVTTTGCKDIIQG RHFEVMLNDAIVCNIGHFDCEIDVAWLKANAKSCENVQPQVDRFTMQSGRHIILLAEGRL VNLGCAHGHPSFVMSNSFTNQVLAQIELWTKSEKYTLGVHFLPKKLDEEVAAAHLEHLGV KLTKLTKEQSEYLGIPQEGPFKPDHYRY-------------------------------- ---------------------------TTVEIDEETYEEIYKNTKRNISMLFVRGDGVIL VSPPMRNMSTSNVENLSPQIIRQVIKELTSLVSDPPEGIKIFFNEEDVTDIQASIDGPAG TPYAGGHFRMKLVLGKNFPNEPPKGFFLTKIFHPNVAKNGEICVNTLKKDWKPDLGIKHI LLTIKCLLIVPNPESALNEEAGKLLLEQYEDYSMRARMYTEIHARPMFKSLLATSSNNPF GGPTGAQINEHRTIAAA-EETSCEFGSGKYYALCGFGGILSCGLTHTAVVPLDLVKCRIQ VDPKKYGSIFKGFRITIAEDGLKGLAKGWAPTFVGYSLQGLGKFGFYEVFKVLYSNMLGE EKSYLYRTSLYLAASASAEFFADIALCPWEALKVRIQTMPGFANTLREGFPKIMQAEGFN GFYKGLIPLWGRQIPYTMMKFAAFERTVELLYKKVVPKPRSECSKPEQLVVTFAAGYIAG VFCAIVSHPADTIVSKLNQAKGSNFIDVGKQLGFMGMWKGLGPRIIMIGTLTALQWFIYD SVKVAFRLPRPPPPEMPESLKKKLAHWKIERYLATGLIFLVPASFIAVLDYALASLVLHA HWGIDTVALDYLHATIIAMAGLINFNYNDVGCVGAVR------NEAQEEDASELTFPKEF ENAETLLISEVKRKQQNENAEEEQELSEVFMKTLSYTTRCSKFKNRETIAAVRNTLMQKK LHKFELAQLSNLCPETAEEAKTLIPSLEGRFEDEDLQAILDDIQNKRSFQYQGQPHLSKQ NLEGLDASKLTPLTPEVISRQATINIGTIGHVAHGKSTLVKAISGVQTVRFKNELVRNIT IKLGYANAKIFKCDSPSCPRPGCYRSQGSAKEDSFPCDRSGCGRFRLLRHVSFVDCPGHD ILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKETQ AKDQYDQILRFVEGTIAEGAPVIPISAQLKYNIEVVCEYIVKKIPVPVRDFTSSPRLIVI RSFDVNKPGCEVSDLKGGVAGGSILRGVLKAGSEIEVRPGIVSKDTEGKLSCEPIFSRVL SLYAEHNDLLYAVPGGLIGVGTKIDPTLCRADRMVGHVLGAVGTLPDIYIELEISYFRLR RLLGVRVEGDAKGAKVQKLSKGEILMVNIGSLSSGGRVIAVKQELAKIGLTHPVCTELGE KIALSRRVDKHWRLIGWGEIRRGITVKPMAELVLDTEIRLWVFLPIVIITFLVGIIRHYV TILLASEKKVELQQIKDSQALIKSRMLRENGKFLPRQAYNMRKRFFNDEQSGFFAKNPMT DPSMMTDMLKGNLTNVLPMLVIGGWINWAFSGFLTTKVPFPLTLRFKPMLQRGVELASLD ASWVSSASWYFLNVFGLRSMYNLILGMDNAADQTKMMQDQMSGAAMAMPQDPQKAFKAEW EALEILNHQWELEKVEEEL---IWDWFSSMLNFLGLMKKSGKLLFLGLDNAGKTTLLHML KDDRMAQHVPTLHPTSEELCMGNMRFTTFDLGGHTQARRVWKTYFPAVDGIVFLVDAYDR ERFPEAKAELDSLLLDEQVADAPVLILGNKIDKPGAASEDEIRQYFGLHGQTTGRGQVPR TDLRPMELFMCSVLKRQGYGEGFRWLAQYINVVRRNRNGTKAADWCTWPEESFDEMDSTL AVQQFIQQAIRKEFANIEEVLTPPEGQDEGVWKYEHLRQFCMELNGLAVKLQAECNPETC TQMTATEQWIFLCAAHKTPKECPAIDYTRHTLDGAACLLNSNKYFPSRVSIKESSVAKLG SVCRRVYRIFSHAYFHHRTIFDEFENESALCKRFTLFVTKYKLMSKDNLIVPILEDQXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSASAIYI LDIKGKVLICRNYRGDIDMSIIDKFMPLLMDKEEEGYTTPILQTGNISFVYTKHNNLYLV ATTRKNANIALVFSFLHRIVHVMTEYFKDLEEESIRDNFVIIYELLDEVMDFGFPQTTDT KILQEYITQEGHKLEVAPRPPVAVTNAVSWRSEGIKYRKNEVFLDVIESVNLLVSANANV LRSEIVGSIKMRVYLSGMPELRLGLNDKVLFESTGRGKSKSVELEDVKFHQCVRLSRFDN DRTISFIPPDGEFELMSYRLNTHVKPLIWVESVIERHQHSRVEFMIKAKSQFKRRSTANN VEIVIPVPNDADSPKFKTTVGNCKYTPEKGAVVWTIKSFPGGKEYLMRAHFGLPSVEG-D EEGRPPIHVKFEIPYFTVSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRTQMGILER ISEIEAEMQRTQKNKATSSHLGLLKARLAKLKRELIEPKGGGGGGGEGFDVAKTGDARIG FVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDG KGRGKQVIAVARTCSIIFMVLDVLKPLQHKKLLEYELEGFGIRLNKEPPNISFRKKDKGG INLNAMVPQSELDPDTVKAILGEYKIHNADISLRFDAKSEDLIDVIEGNRIYIPCIYVLN KIDQISIEELDIIYKVPHCVPISAHHKWNFDDLLEKMWEYLELVRIYTKPKGQLPDYSAP VVLKDGKSTVEDFCNKIHRTILKEFKHAVVWGSSVKYQPQRVGKEHVLNDEDVVQLVKKM AKHHPDLIFCRKQPGVAIGRLCEKCDGKCVICDSYVRPNTLVRICDECNYGSYQGRCVIC GGPGVSDAYYCKECTIMEKDRDGCPKIVNLGSAKTDLFYERKKYGFKKR----------- --KTGCQSVPVPKNRFTPLKENWMKIFSPLVEHLHLQIRFNLKTRNVELKTCKETKDIGA LQKGTDFVTAFILGFDVEDALALVRLDDLYLESFDITDVKPLKGDHLSRAIGRVAGKNGK TRFTIENVSKTRIVLADTKIHILGSYNNIRVARTAICNLILGSPPSKVYGNLRTFAAQTA ERRIKVANPVVDLDGDEMTRIIWQQIKDKLVLPYVDVDIKYYDLGLPYRDQTNDQVTIDC AEAIKKYNVGIKCATITPDEERVEEFKLKKMWLSPNGTIRNILGGTVFREPILCNNIPRI VPGWTKAIVIGRHAFGDQYKATDTVLTGNGKLELVFTPDKGEPQRLEVFEFTKGGGVGLA MYNTDESIAAFGESCFQYAIMKEWPLYMSTKNTILKRYDGRFKDIFEDLYQKKYRAQFEK LGIWYEHRLIDDMVAQALKSNGGFVWACKNYDGDVQSDIVAQGYGSLGLMTSVLVCPDGK TIEAEAAHGTVTRHYREHQKGNPTSTNPVASIFAWTLGLAHRGKLDGNQDLIKFAKGLEK ACITTIEDGKMTKDLAGCIVGIKNVKPDMYLNTNDFMEAITEQL-MGKLLSKIFGNKEMR ILMLGLDAAGKTTVLYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDRIRPLWR HYYTGTQGLIFVVDCADRDRIDEARQELHKIINDREMRDALILIFANKQDLPDAMKPHEI QEKLGLTRIRDRNWYVQPSCATTGDGLYEGLTWLTSNHKSFGDLKSTAGLKALNDYLGDR TYIEGYQPSQADAVVFAALSCPSSDLYHALRWYNHIKSYGSETNKFPGQKKALSDYGAPG SKKADDDDDFDLFASAFADVEAAK-KAITEKKSPGLIAKSN------------------- ----LQTDGLVWGASKLLEVAFGIKKLQIVVVVEDDKVGTDYLEEEICKFEDYVQSVDIV AFNKV--------------------------DALEARAVSQGMVGQTSARKAAGVILEMI RDGKIAGRAVLIAGQPGSGKTAIAMGVAQALGTDTPF--MAGSEIFSLEMSKTEALTQAF RKSIGVRIKEETEIIEGEVVEIQIDRPATGTGAKVGKLTLKTTEMETIYDLGQKMIESLT KEKVSAGDVITIDKATGKITKLGRSFTRARDYDAMGAQTKFVQCPEGELQKRKEVVHTVT LHEIDVINSRTQGFLALFSGDTGEIKSEVREQINSKVAEWREEGKAEIVPGVLFIDEVHM LDIECFSY---------------------------------------------------- ---IKQILKIRCEEEDVEITDDALTVLTRIGLETSLRYSIQLITLSMLVSRKRKAVEVDV DDIKRVYSLFLDESRSSEFLKEYQQEFMFNEMAEFDLTRKISPYLDRHLVFPLLEFLTVK ELYHEDEMLKGKLELLSNTNMVDFAMDVHKCLYPDQEVPTMLKEKRTDVVNELKRLQMDV DPITKIFEDQEVQIQSSRDGRQLFEWLAKNHNFQASMLTTLYKFAKFQYECGNYSGASEY LYFVRALIPSNDKNYLNALWGKLASEILMQNWDAALEDLNRLKEIIDSPLQLLQQRTWFI HWSLFVFFNHAKGRDLIIDLFLYQPTYLNAIQTLCPHILRYLTTAVITNKSVLKDLVKVI QQESYTYKDPITEFLECLYVNFDFDGAQQKLRECETVLLNDFFLVACLDDFIENARLFIF ETFCRIHQCISINMLAEKLNMTPEDAERWIVNLIRNARLDAKIDSKLGHVVMGTQAVSPY QQVIEKTKALSFRSQMLCINLEKKLGVKTMGVEVKTEQPGDGVTFPKKGQTVSVHYTGTL ENGKKFDSSRDRGKAFEFKIGMGQVIRGWDEGVAQM------------------------ -------------------KYYCDYCDTYLTHDSPSVRKTHCNGRKHKENVRIYYQKWLE EQMQKLVD---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------IYISRIIPGGVADRHGGLKRGDQLLSVNGVSVEGENHEKAVDLLKAAHGAVKLV VRYTPKVLEEMEARFDKQRTAGR--------------TVYFVDKFPIGRWIESTHR-SDQ GKWEWTAGKFYGDAEKDKGLQTSQDARFYGISQKFDS-FSNEGKTLVIQFTVKHEQNIDC GGGYVKIFPSDLNPKDMHGESPYAIMFGPDICGPGTKKVHVIFNYKGKNLLTKKDIRCKD DVFTHLYTLIVRSDNTYEVKIDNEKVESGDLESDWEFLPAKKIPDPDAKKPTDWDERETI ADPDDKKPEDWDKPEHTPDPEAKKPDDWDDEMDGEWEPPMIDNPDYKGEWKAKQIPNPDY KGKWVHPLIDNPDYKEDKELYKYSDLSYVGLDLWQVKAGTIFDNFLITESEKYAEEFGNE TWGKTKEGEKKMKEKQDEEERIKREAEEKKAKEEKKDEDDKDDK---------------- ------------------------------------AEIIMLEGLTCVYRSNVDLFFYVI GSAQENELILVSVLNALYEAISQMMRKNVEKRALLDNLDAVFLAIDEICDGGIILEADPT TIAQRVSIRNEDIPLGEQT------------------MNIFRLVGDLSHLLAIILLLLKI WKTRSCAGISGKSQIMFALVFTTRYLDIFTNFISVYNTCMKAIFIGASYATVYLIYMKFK ATYDSNHDSFRMEFLIVPVGGLAVLVNHDFSFMEILWTFSIYLESVAILPQLFMVSKTGE AETITSHYLFALGSYRALYLLNWVYRYYFEGFFDLIAIVAGCVQTILYCDFFYLYITKVL KGKKLSLPAMKIEEVKSTTKTQRIAAHSHVKGLGCDENGYAIQSSAGLVGQELAREAAGI VVDLIKSKKMAGRAVLLAGPPGTGKTAIALAIAQELGSKVPFCPMVGSEVYSTEIKKTEV LMENFRRAIGLRIKEVKEVYEGEVTELSPVETENPMGGYGKTVSHVVIGLKTAKGTKQLK LDPSIYESLQKEKVEVGDVIYIESNSGAVKRQGRSDTYATEFDLEAEEYVPLPKGDVHKK KEIIQDVTLHDLDIANARPQGGQDIMSMLGQLMKPKKTEITDKLRKEINKVVNKYIDQGI AELVPGVLFVDEVHMLDIECFTYLHRALESTISPIVIFATNRGRCTIKGTEDIIAPHGMP LDLLDRILIIRTLPYSKEEMSQIIRIRAQTENLNFSEEAISLLSEIGVKSTLRYAVQLLS PCSILAKINGKDAIGNEEIEEMNELFYDAKSSAKILAEQSDKYMKEFEVDDEGDQGLQRL KEKVKRRKGRGFVTRSGVEDYEAMETDGPGPQRSIEGWILFITGVHEEAQEDDIQDKFAE YGEIKNVHLNLDRRTGFLKGYALVEYETFKEAQAALDNINGTDILGQKCCVDWAFVRGPT GKKMSYQLYRNTTIGHTLQESLDELIQCSQITPQLALKVLLQFDKAINQALANRVKSRVG FKGKLNTYRFCDNVWTFVLNDVEFRRVDKVKIVACDGK-TFLFTSESVGEGHPDKICDQV SDAVLDAFLKEDPDCKVACESASKTGMIMVLGEITSSANIDYQKTIRDTIKRIGYDASEK GFDYKTCNVLVAIEKQSPDIAQGVHVGRDDDDTGAGDQGLMFGYATDETEECMPLTVVLS HKLNAKIAELRRSGEMAWARPDSKSQVTIQYKFVDGACVPIRIHTIVISLQHDDKITLEK LRSELMEKVVSVVVPQKLIDDKTVYHLNPAGRFVIGGPQGDAGLTGRKIIVDTYGGWGAH GGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCKRVLVQLSYAIGVAEPLSICVFSYGT SAKSENELLEIVKKNFDLRPGRIVKDLRLKDPIYSKTACYGHFGRPEFTWEQPKKLVFMA GSALKRLMAEYKQLTLNPPEGIVAGPVKEENFFEWEALITGPEGTCFEGGVFAARLTFPP DYPLSPPKMKFTTDLFHPNIYQDGRVCISILHAPGDDPMGYESSAERWSPVQSVEKILLS VISMLAEPNDESAANVDAAKTWRDDRDKFESIAATTVRKSLGLXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMATYEVVFIRHGASEWNKSNRFCGWVDVDLTEKGVEEARVAGQALRNENFTFDIIYT SLLKRAIKTTFVLQDCLDLHWIPVIRSWRLNERHYGALTGRIRTDVVEEYGKEKVKFWRR SYEGCPPLCNEDNMCPTPGDKKYEHIDRTCLPKGESLKDTMKRVLPFWFDEIVPAIKNGK KVLLTTHGTSIRSIIKHLDKIPDSDIDTFDIPTGIPLVYELDQDLKPVKHRYLADEKLVA DEIEKIRNQ----MELSDLYYSKAEYIETASGNKVSRQSVLCGSQNIVLNGKTIIMSDCI IRGDLANVRIGRHCVISRRAVIRPPFKKFSKGVAYFPLHIGDHVFIDEDSVVNAAQVGSY VHIGKNCVIGRRCVLKDCCAIADNTVLPPETVVPPFTLFSGSPGMSFLFGGRNNKTFKPK KNIPEGTHQYDLMKHAAATLGSGNLRLAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTIT EFCTEESCSVMSAGPKYEYHWADGTTIKKPIKCSAPKYIDYLMTWVQDQLDDESVFPSRI GVPFPKNFLS-------------------------------------------------- -------------------MGVDIRHNKDRKVHRTEPKSQDVYLRLLVKLYRFLARRTNA KFNKIILKRLFMSKIHRPPLSLARLIRFMKKEGREGKIAVCVGTITDDLRILEVPKLTVC ALHVTENARHRILKSGGEIMTFDQLALRSPKGKGTVLIQGPRKAREAVKHFGRAPGVPHS HTKPYVRSKGRKFEQARGRRASRGYTNDLKQGNITGSYEVARTVHILRRIVSQTKWANAG ELMEIIRREGRKMMESQPSETAVGNMVRRVLKIVREEYVAEAIGEFITELETSAQALEHV HANEVIETVQGFLKAKFHVIVVEYNGQELAMNLASSGIETTVITDSAVFAIMSRVNKVII GTHTVMANGGLKGVGSHAIALAAKHHSVPLIVCTASFKLSPQYLCSHDDAFNKFISPDDI QNPVFDYVPPELVTLFISNIGGNAPSYIYRLLSELYHMIIPVRCFTCGKVIGNKWEAYLG LLQAEYTEGDALDALGLKRYCCRRMLLAHVDLIEKLLNYAPLEKKSPEAVEGRKHIDVQT ELYLEELSDRVEEADVECQTDAFLDRPPSPLFVPAKSGVDIATQIEDGDLFNFNIEVKPI LEVLVGKTVEQALLEVMEEEELANLRSQQRAFEELRNAELVEQQRLEEQERRHREEKERR MKQQRDILTKEKETADKIAARAFAQSYLSDLVPTVFGTLSDHGYFFDPVERDIEQGFLPW LMEKVDDKLTKVNYGRMVLDGIIRDVVKNKFHLYKKMKARGLLKEYKVVGREMPTTKLPV PPLYQMKIFAPDKPTAKSRFWYFVQNLRKMKKSRGEIVLCQQIFEKRPTKVKNFGVWLRY DSRSGTHNMYREYRDLTVASAITQCYRDMGARHRARACSIQIMRVEEIEASKCRRANVKQ FHNSKIKFPLPHRVKRPLHNPRFTTTRPHTTF--------XWRKNEFRPLSPLSIYKPQL TSMLSIIHRVSGIGMGCVIYAFS------------------------------------- -----------------------------------------SVVLSAYRDQHFKGSRQDQ DALLKKTTTLYIGNLSFYTTEEQIHELFSKCGDLKRVVMGLDKVKKTPCGFCFVEYYTRR DAEYSMRYINGTRLDDRIIRSDWDAGFKDGRQFGRGKSGGQVRDEYRSDYDSGRGGYGKI VVNKL--------TLAGHTKAVSSVKFSPSGEWLASSSADKLIKIWGAYDGKFEKTISGH KLGISDVAWSSDSKLLVSASDDKCLKIWDVASGKSLKTLKGHSNYVFCCNFNPQSNLIVS GSFDESVRTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG KWIVSGSEDNQVYIWNLQSKEVVQKLQGHTDVVLCCACHPTENLIASAALENDKTIKLWR SDVMIVFQCRFCGDEMFTDSSPDTYYVVTPTDPSLLGANASSGLDIIINEKKKFQAWCKT YLKKIKDYQIYAGLAILDWNTPTFIYLKDGLKEVK-MAVQYNGGVVVGADSRTTTGSYIA NRVTDKLTPITEYIFCCRSGSAADTQAIXDIVKYELSLYKATHGKEPSVHTAARTFQRMC YQYRDQVSAGIIVGGWDMXNGGQVFSVPLGGMILQQPISIGGSGSTYIWGYIDATYKENM TKEQCLKFTADALALAMGRDGSSGGVIRLAAISKDGVER-----------VAIAVVAGLL LLCCCFCICKKCIKKKKDKGGKKG-KGGVDLK-----------------KELDGNMEGED DNESTKEEVNLGKLQFSLDYDFQKGELQVGVVQASDLPGMDMSGTSDPYVKVYLMPDKKK KYETKVHRKTLNPVFNETFTFKVPYAEIASKTLVFAVYDFDRFSKHDQIGLVKIPLNSVD LGRVIEEWRDLTSPESDADKENKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSD PYVKIALTQGTKRLKKKKTTIKKRTLNPYYNESFTFEVPFEQIQKVSLIITVVDYDRIGT SEPIGRTVLGCNSSGAELRHWSDMLANPRRPIAQWHTLQEMPEKSMVLAELGRKITTALR GLSNATIINEEVLNAMLKDICAALLEADVNVQLVKKLRENVRSVIDFDEMAGGLNKRRMI QSAVFKELVKLIDPGVKAWTPTKGKNNVIMFVGLQGSGKTTTCTKLAYFYQRKGWKTCLI CADTFRAGAFDQLKQNAVKARIPFYGFMTKGNEEESMRRLKRLMTIMDS----------- ----------------------NDAELDSPE--GAKLFSRGRVQRVARGAGVSATEVKDL LSQKFAQMVKKMGGIKGLFK-GGDLPSKVPAQMSKLNQQMAKVIDPRVLQQMGGMNGLQS MMRQFQQGAMSIMSINGSATMAMAGKNCVAIGCDLRFGMQAQTIAMDFEKIYEIGPHLYV ALPGLQTDAQTIAQRLEFRSKLYELKENRNLKPKTFMAMVSNLLYERRFGPYFVEPVIAG LDPVTAEPFIANLDLIGCPMVTEDFVVCGTCSEQMYGMCESLYEPNLGPDDLFETMSQAL LNAVDRDAVSGWGAVVYIIEKDKVTKKTLKGRMDMTSKDYYFDSYAHFGIHEEMLKDEVR TFTYRNAMCHNKHLFRGKIVLDVGCGTGILSMFAAKAGAKRVIGMECSGIIDHAQKIIDA NGFTDVITLIKGKVEEVSLPEGIEKVDIIVSEWMGYCLFYESMLNTVIYARDKWLAPDGL IFPDRACLYVTAIEDRQYKDEKINWWDNVYGFNMSCIRKVAITEPLVDVVDKNQVVTNSC LLKEVDIYTCTVDDLTFSSPFVLTCKRNDYIQALVTYFTIEFTKCHKRTGFSTAPDARYT HWKQTDDTITMQNKDEIVGSFSVKPNEKNNRDLDFKINLDFHGEFSDVSESITYKMRMVK EDRTTWKSNYFLKVVKYLDEYSKCFLVNADNVGSKQMQLIRAALRILFGKNTMMRKAIRG HLENNPQLEKLLPYLKGNVGFVFTKGDLNEVRAKLLEHKVAAPAKAGAIAPVEVIIPAQN TGMGPEKTSFFQALNIPTKIARGTVEILSDVHLIKVGDKVGASEASLLNMLKISPFTYGL VIEQVYDSGTVYSPTILDITDDDVRISFMQGVRNLAAVSLEIGIPTVCSVPHSLINGFKN LLAVAVETEYDFPEAEQTKEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXX----------------------------------------- ----PELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGMSQFSVKGDKESKLRFAFKIYDMD KDGYISNGELFQVLKMMVGNNLKDSQLQQIVDKTIMYADADGDGKISFNEFCDVVATMDV --------MTYISSWEEFSRASEKLYLADPMKCRFCLKYRHCDGKLNLKVTDDRVCLQYR SEHAQDVKKMEKFVGQLMRHMTSRDLYEEVKLYRTSKEREKYDNMADLFAVINTLQALEK AYIKDAVTPKEYTAACSKLLVQYKAAFKQVQNEDFPNVEAFMSKMKLDCPAALERIKEDR PITIKDDKGNTSKFIADIVSLFITIMDKLRLEIKAMDQIYPDVKDLYESMHSLSILPNDF EGLGKVNNWLKTLGEMGASDELDDSQVRQMLFDFEFSYNAFSRVLH-XXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXATIVTKPI----KAGER KVRVSKMPRYYPTEEPKRKLRTPFSQQKRHLRSSITPGTVLILLAGRHKGKRVVFLKQLA SGLLLVTGPYHLNKCPLRRINQIYVIATKTKLDISKVKVPERVNDEYFKRQKAAKQKQGE GEIFATKTEKYQISPERKEDQLAVDKAIMEVIKSTDKKKLLTGYLGTTFSLSNRQYPHKM VFLEWLFGRRKTPEEMLRQNQRALNKAMRDLDRERSKMEQQEKKIINDIKKMAKQGQMDA VKIMAKDLVRTRRYVKKFILMKANIQAVSLKIQTLRSQNAMAQAMKGVTKAMKTMNSQLK LPQIQKIMMEFEKESEIMDMKEEMMNDAVDDVLGDEDDEEESDAVVSQVLDELGLQMADQ LSDLPAAKQAAAKAP-AVSDADADLEARLDNLRRQSSYCDFCLGDATENKKTTLAEDLVS CADCGRSGHPTCLQFTENMITSVKKYPWQCIECKSCGICGTSDNDDQLLFCDDCDRGYHM YCLKPPLSEPPEGSWSCHLCIIEFHGALERRITLYPLTNYTFGTKEALYERDASVQARFN RMKEEFYKIGMRKTVDGVLIVHEHGLPHVLLLQLGTTFFKLPGGELDNNENEIDGLKRLL TETLGRQDGAAMVWTVEDVIGNWWRPNFEPPQYPYVPAHITKPKEHRKLFLVQLPEKALF AVPKNYRLVAAPLFELYDNSQGYGPVISSLPQALSRFNFMYNFTPSGTTPSGAKAMAMAT PTPGHLVSMTPEQLQAYTWQREIDERNRPLADDELDSIFPPGYKILPPPAGYAPIRTPAR RLLATPTPLQGTPAGFRMQGQVVDMQPKGNLPMMKPDDIQYFDRKIMKLLLKIKNGTPPM RKAALRQITDKAREFGAGPLFNQILPLLMSPTLEDQERHLLVKVIDRILYKLDDLVRPYV HKILVVIEPLLIDEDYYARVEGREIISNLAKAAGLATMISTMRPDIDNMDEYVRNTTARA FAVVASALGIPSLLPFLKAVCKSKKSWQARHTGIKIVQQIAILMGCAILPHLKSLVEIIE HGLVDEQQKVRTITALALAALAEAATPYGIESFDSVLKPLWRGIKQHRGKGLAAFLKAIG YLIPLMDAEYANYYTREVMLILIREFQSPDEEMKKIVLKVVKQCCATDGVEPQYIKDEIL PPFFKHFWNQRMALDRRNYRQLVDTTVEIANKVGAAEIISRIVDDLKDEAEQYRKMVMET IEKIMANLGSPDIDSKLEEQLIDGILYAFQEQTTEDVVMLNGFGTVVNALGKRVKPYLPQ ICGTILWRLNNKSAKVRQQAADLISRIAVVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLG SILGALKAIVNVIGMTKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGSEYVS AREWMRICFELLELLKAHKKSIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVC TTVAIAIVAETCSPFTVLPALMNEYRVPELNVQNGVLKSLSFMFEYIGEMGKDYIYSVTP LLEDALMDRDLVHRQTSMAAIQHIALGVYGFGCEDALVHLLNYVWPNVFESSPHVVQAFM GAIEGIRVGLGPSKLLQYALQGLFHPARKVRDVYWKVYNTIYIGAQDAMIPSYPRVPDDH KNNYSRYELDYVLDDFMD-DEDYDLEYSEDSNSEPDVDLENQYYNSKAKKEDSPQDALHS FNKVLEMEGDNKGEWGFKALKQMIKINFKLGRQDEMLAKYKQLLTYIKSAVTRNYSEKSI NSILDYISTSKEMELLQRFYEITLDALREAKNDRLWFKTNTKLGKLYYDRADYTKLQKIL KQLHLSCKTDSGEDDMKKGTQLLEIYALEIQMYTAQKNNQKLKALYEQSLHIKSAIPHPL IMGVIRECGGKMHLREGMYEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSDIN PFDSQETKPYKNDPEILAMTNLVSAYQNSDIAEFEQILNTNKKNIMEDPFIKEHIEDLLK NIRTQVLMKLIKPYTRIKIPFISKELNISEQEVENLLVSCILDNTIQGRIDQVNHVLELH TKAARYTAIDNWSAQLQTLHQAVLNKM-VLLMGKSGSGKTSMRSIIFANYIARDTRRLGA TIDVEHSHVRFLGNLVLNLWDCGGQEAFMENYFASQRDNIFRNVEVLIYVFDVESRELEK DMHYYQSCLEAILQNSPDAKVFCLIHKMDLVQDDQRDIIFHEREEDLKRLSKPLATSIWD ETLYKAWSSIVYLLIPNVQQLETNLTNFANIIDADEVLLFERATFLVISHCQRKAHRDVH RFEKISNIIKQFKLSCSKLAASFQSMEVRNSNFASFIDVFTSNTYVMVIMSDPTISSAVT LINIKNARKHFEKLERLDQILSFATRLFSVLRFESVIHEFDPYFNYRTTRYLTEEGFYNF HNWFDDRAWYPLGRIIGGTIYPGLMVTSAVLYNILQFLNISIDIRNVCVFLAPFFSSLTT IVTYHLTKELKDAGAGLVAAAMISIVPGYISRSVAGSYDNEGIAIFCMLLTYYLWIKSVK TGSVYWAALCGIAYFYMVSSWGGYVFLINLIPLHVLVLMITGRFSHRIYVAFSTVYGLGT ILSMQISFVGFQPVQSSEHMAAFGVFGLCQILAFVNYVKSRLNQDQFNTLFRTAILILGL GALMATGKIAPWTGRFYTLLDPSYAKNNIPIIASVSEHQPTTWSSFYFDLQMLVFMFPAG LYFCFKKLTDANIFIIMYGITSIYFAGVMVRLMLVLAPVMCILSGIAVSSTLSTYMKNLE LPKKADSTYPIKTEVATGVVLMMSLFLITYTSHCIWVTSEAYSSPSIVLSARASDGGRII FDDFREAYYWLRHNTPPDAKVMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMAS TEEKAYEIMRELDVNYVLVIFGGLTGYSSDDINKFLWMVRIGGSTDRGRHIKEHDYYTPQ GEFRIDKDGSKTLLNCLMYKLCYYRFGAVYTENGKPTGWDRVRNAEIGNKDFQLDVLEEA YTTEHWLVRIYKVKDLENRGNKLNIRPLMKLILNRFIGDFTGFVDMCVEHINSPLTNAKN KIEHIYTGPDDTELYESMRICDPDGPLMIHTTKLYPTHDATAFHVFGRVMSGTLHANQEV KILGENYSLQDEEDSRFGQVGRLWIYESRYQIEVNRVPAGNWVLIEGIDQPIVKTSTITE PVGNDEAFIFKPLKFNTSSVIKIAVEPVNPSELPKMLDGLRKVNKSYPLLTTKVEESGEH VVLGTGELYLDCVMHDLRKMYSEIDIKVADPVVSFCETVVETSSLKCFAETPNKKNKITM IAEPLEKGLAEDIENEVVQITWPKKRLGEFFQTKYDWDLLAARSIWAFGPDTTGPNILVD DTLPSEVDKNLLNSVKDHIIQGFQWGTREGPLCDEPIRNTKFKI---------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------EAFNLFDNRGDEKI YAYQLGEVLRAMGQNPTEAEVKKCSEPERRISFEEFIPILHTVSKNRDQSTPEEFIEGFK VFDKEQNGTISSAEFRHLMTHLGERLKDEEVEQLLGGQEDSQGNIAYEEFVRMVMS-MSE LYFNIDSGYLEGIVRGFKGGILKQTDYLNLVQCETLEDLKLHLQSTDYGNFLANEPSPLT VSVIDDKLKEKLVVEFQHIRNHSLEPLSTFMDYITYSYMIDNIILLITGTLHQRSISELI PKCHPLGSFEQMEAIHIASTPAELYNAVLVDTPLAPYFIDCISEQDLDEMNIEIIRNTLY KAYLEAFYNFVSELGGPTADVMGEILAFEADRRAFIITINSFGTELTKDDRAKLYPTCGK LHPDGLAALARADDYEQVKAVAEYYAEYRALFEGAGNNPGDKTLEDKFFEHEVKLNVNAF LQQFHYGVFYAYVKLKEQECRNIIWISECVAQRHRAKIDSYIPILSPRKAVRKISKIPFK VLDAPELQDDFYLNLVDWSSTNVLSVGLGTCVYLWSACTSQVTRLCDLSSDGDSVTSVSW AERGHLVSVGTHKGDVQIWDVAASKKVSVLEGHSARVGTLAWNADMLSSGSRDRLILQRD IRTPSIVPERRLTGHRQEVCGLKWSPDRQHLASGGNDNKLYVWNMNSTTPVQTYTEHLAA VKAISWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCVDTGSQVCNLAWSKHANELVST HGYSQNQILVWKYPSLVQIAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTR STKESKSVLNMFTHIR-LVIISLYYILSGQGYRFDIGWVLETTSPYMWASIGIGLAISLS VVGAAWGIFVTGSSILGGGVKAPRIKTKNLVSIIFCEAVAIYGIIMAIVISNSTNYFAGY AMFGAGLTVGLSNLACGICVGIVGSGAALADAQNSSLFVKILIVEIFGSAIGLFGVIVGI LQISRAKMGDKMAATRRLAKELKDEASECNILEWTCVLLPDSQPYNKGAFKLKITFPAEY PFKPPKINFETKIYHPNIDEKGQVCLPIISPENWKPATKTDQVIQALLALVNEPEPEHPL RADLAEEYQKDRKKFMKNAEEFTKKHSEKR---DAAETELCKGSALRTGKYCMLKNNPCK IVSTSTSKTGKHGSAKVHITGLDIFTGKKCEEIFSSTADCKCPIVLRKDYSVLDITEGYL TLMDEGGVTREDIKLPVTVQAAMGREAVTEHKTMKENLLGPKSCVVCKEATVSSQCNENS NDITCSSHAGVQLQFFCTT--------------DHNLIVVDSDNCRVQEFTDGQHIQTKG MKGREEGEFDWPQGVVVDAEGNILIVDRGNRRLHVFNEDLEFVC---------------- ------------------MAAGPIAERNQDATVYVGGLDDKVSEAILWELFLQAGPVVNV HMPKDRITQAHQGYGFVEFMAEDDADYAIKIMNMIKLYGKPVRVNKASAHQKNLDVGANI FIGNLDPEVDEKLLYDTFSAFGVILQTPKIMRDPDTGGSKGYAFINFASFEASDASIEAM NGQYLCNRAITISYAFKKDSKGERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPQA-- -LPPPAPPVSMTPPPPPPDLSGMGM---GIPPPGSM--------PPPPSGGPPPPGMRFP PPPPPPRGHGPPPGMRPPPPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXMRYVAAYLLASLGGNKNPSKADIEKILSSVGIEADSDRVAQ VIKELSGKNIEDLIKNGKEKLASVPSGGAVAAAEEKKEEESDDDMGFGLFDMSITKVHAR QIFDSRGNPTVEVDLTTHKGTFRAAVPSGASTGIHEALELRDKEKDKYHGKSVSKAVEHV NKTLGPAVILNVKEQEKLDNLMIDLDGTPNKSKFGANAILGVSLAICKAGAAEENVPLYK HIANLRGHKEVVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFSEAMRMGTEIYHHL KAVIKAKYGQDACNVGDEGGFAPNILENKEGLNLLTEAIEKAGYTGKIKIAMDVAASEFY KKYDLDFKNENSDQTQWKSPDELADLYMEFINEYPIVSIEDAFDQDDWDAWSNFNAIQIV GDDLTVTNQTRIQTAIDKKACNCLLLKVNQIGSVTESIKAAKLSNDNGWGVMVSHRSGET EDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEQLGDKAKYAGEKFCNP----- ----KERPAAPTSFRKFYERGDFPIALEHDTKGNKIAWKVEIEKLDYHHYLPLFFDGLCE TGHPYEFFARQGVHDMLEHGGSKILPVIPQLIIPIKNALNTRQKHVICTTLKIIQHLVVS GEMVGEALVPYYRQILPILNIFKNENLNSGDGIDYSQQKRENIGDLVAETLSALETHGGS DAFINIKYMVPTYESC-MNAPPTFESFLLFEGEKKVTIQKDTKVPNAAIFTIKKEDHTLG NALRTQLLKDPQVLFAGYKIPHPLESQFVLRIQTTPDYSPQEAFQNAITDLISEISLLEE QFRDAVKEKQEGDEDHRRKWDRDEYEQMAQKRLEEE-------LQKELLKPRDYRVDLES KLGRSQVITKTTPLAQQGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMKVER---- ------------------------------------------------------------ --------------MGCTMSAEDRLAMERSKAIEKNLKEDGIQAAKDIKLLLLGAGESGK STIVKQMKIIHEGGFTSEDNKQYKPVVYSNTIQSLVAIIRAMGTLNIPFGDNERESDAKM VLDVIARMEDTEPFSEELLAAMKRLWVDSGVQECFGRSNEYQLNDSAKYFLDDLDRLGAK DYMPTEQDILRTRVKTTGIVEVHFSFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCV AMSEYDQVLHEDETTNRMQESLKLFDSICNNKWFTDTSDEKIKKSPLTICFPEYTGKQTY EEAAAYIQAQFEAKNKSTTKEIYCHQTCATDTNNIQFVFDAVTDVIIANNLRGCGLYYHS AI-PVQQSICKVALLPIKTKFKGPAVDIIDESITYFKANVFFRNFEIKTDADRTLIYITL YITECLKKLQKCRSKNDGLKEMHSL--------------------------EEDTMRNYF LQLRQETGLRIVDKVFDSASDRPSKWWMCFVKRKFMDKSLSAPGQAGPYNYSYIFKYIII GDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVT RSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIFLIGNKCDLEDQRDVTYE EAKQFAEENGLMFLECSAKTGENVEEAFLDTAKRIFQNIQDGSLDLNAAESGVQHRPSGG GTQQLSGDTTTKEGCSC----AVCVLRDSEVIGTVQFCQEDGTVVSGEIKHLAEGRHGFH IHEFGDNTNGCASAGAHFNPDGKLHGGPKDEERHAGDLGNVVAGIIDITDTQIPLIGKNS IIGRTVVVHAEEDDLGKGCYDDSKTTGHAGARLACGVIGICK-----VDDIRAQMDRKTN IRNMSVIAHVDHGKSTLTDSLVSKAGIIADSKAGDARFTDTRKDEQERCITIKSTAISLY YEVPDELMGNSFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQA ISERIKPVLFMNKMDLAISSRQLDEEELYQAFCRSIENMNVIVSTYEECEKLMGALQVTP ENGTVGFGSGLQSWAFTLRNFANMYADKFKIEVNKLMKRLWGENYYNYTRGFSLFVLKPI YTVIDLVKPREDIFKFVEKLKIFLTPDEKDLELKKLGKMIMQRWLPAGDALLQMICIHLP SPLTAQNYRMELLYEGPHDDDAAVAIKACNPEGPVMMYISKMVPTSDKGRFYAFGRVFSG TVASSQKVRIMGANYVPVKSIQRTVLMMGRSVEQIEDVPCGNICGLVGVDQFLVKTGTIT TFEQAHNMKVMKFSVSPVVRVAVEAKNGADLPKLVEGLKRLAKSDPMVQCIIDETGENII AGAGELHLEICLKDLEEDHACIPIKSSKPVVSYRETVSEDSSIMCLSKSPNKHNRLFVRA AEMEEDLSKAIDGGDITPKMDFKVRARTLADKFGWEVGEARKIWAFGPEATGPNLVVDVT KAVQYLNEIKDSVVAGFQWASKEGVLCEENMRGIRFNIHDVTLHADAIHRGGGQIIPTAR RVFYAAELTGAPRLMEPIYLVEIQCPQAAAGGIYGVLNRRRGIPLGETNESQGSQVNAKA YLPVNESFGFTADLRSATGGQAFPQCVFDHWAKLIVKETRARKGLSEGVPPLDKFLDKLM LPLSLLKTAINHPMLVELKNGETYNGHLVSCDNWMNINLREVICTSRDGDRFWRMPECYI RGSTIKYLRIPDEVIDMVREESVQKSKGRGESRQRGRGG-GRGTFGGRGG--GGGGRG-- ---AEFKLNDPPTDGISAVKFSQTSPQYLLVSSWDQTVRLYDVVNNSLRTKYSHSAPVLD CCFQDSVHSYSGGLDNTLKMYDFNQSVEKQVGTHEAPIRCVEFCNDTNVVVTGSWDLTVK LWDPRGPTAAGTFTQPDKVYTLSVTGDRLVVGTAGRKIVVWDLRNMGYVQQKRESSLKYQ TRCIRCFPNKQGYVLSSIEGRVAVEYLDPNPEIQKKKYAFKCHRLKEDGIEKIFPVNAIS FHNIHNTFATGGSDGFVNIWDGFHKKRLCQFHRYPTSIASLSFSQDGSTLAIATSYMYEQ GIPDDNIYIRTVTDQETKPKMDFQHRAGGKTGTGGVASASDANRDRRERLRQLALETIDL MKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQTNLARRAAKEAKEAPAQPAPE KA-VEIKKFVKIGRPGYKVTKQRDPDSFQQSLLFQIDYPEISE-VYPRHRFMSAYEQKVE PPDRKWQYLLFAAEPYETIAFKVPSREVDKDPKKIWTHWNKETKQ--------------- ------------MEDDHEAYKLWRIRKTIMQLCHDRGYLVTQEELDQTLDQFKEQFCARI GT-PISRNDLTVLVAHNDDPTDQMFVFFPDEPKVGIKTVKAYCQTMQKENIHRAIIIVQM GMTPSAKMSLVDMAPKYILEQFLEAELLVNITEHQLVPEHVLMTPEEKKELLDRYRLKES QLPRIQQGDPVARYFGLKRGNVVKIIRPSETAGRYITYRLVV------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------PTAAAIAYGLDKKEGEKNI LVFDLGGGTFDVSLLTIDNGVFEXVSTNGDTHLGGEDFDQRVMDYFIKLYKKKKGKDIRS SNRAVQKLRREVEKAKRALSSGHNARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTLK PVKKVLEDAELEKKDIAEIILVGGSTRIPKVQQLVKEFFNNKEPNRGINPDEAVAYGAAV QAGVLSGEEDTGDLVLLDVNPLTMGIETVGGVMTKVIPRNTVIPTKKSQIFSTASDNQNT VTIQVYEGERPMSKDNHFLGKFDLTGIPPAPRGVPQIEVTFEIDVNGILKVSAEDKGTGN KEKITIKNDQNRLTPEDIERMINDAEKFSDDDKKVKEKVEARNELESFAYSLKQQINDKE KLGAKLSSEDKEKLEKVVNEKIEWLDKNHEADTEEFKKHKKELEEFANPIISKIYKDQQQ QGGEANKDELEESMEDPELEAIKARVREMEAEAEKLKEMQNEVDKQMSAEEKVEVDNRSV YVGNVDYGATAEELEAHFHGCGSVNRVTILCDKFSGHPKGFAYVEFADKDSVSTAQALDE SLFRGRQIKVTPKRTNKPGISSTNRPPRGGF-RGRGRG---------------------- ----VLSSTLAEIIQRGSFKSLLKAVELEKNAKQDLQNTILKEEEGRKRLRFLQKQILEV KKEKEVELQNRNEMIAHLKDQLQEMKAKTSMEGKYIKKCAEVGVAQTQKKCMLSEKECKD EIDELRAKIDEETRVHEEIRSFLQSQQTELESKLEFWMEKYDKDVEAKQHELDVWKMAKA KDLEKLQELTKTYQEYEEIVVEDRIQKEKAKRKAEQEALELKSCVQLQAWWRGMCVRKAI GPYGKKKKK-PQVGINGFGRIGRLVLRAALLSVDVVSVNDPFIDGEYMVYMFKYDSTHGK WDGEVSLVVGKQHIYIHAEKDPASIPWAKDGAEYVVESTGVFTTKEKAGAH---KCKKVV ISAPSADAPMYVMGVNHNSYTKENNIVSNASCTTNCLAPLAKVINDEFGI---------- ----------PSAKQWRDGRGAGQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPVPDV SVVDLTVKLGKAASMDAIKAAVKGDLKGYLGYTEDAVVSQDFRSDSHSSVFDAKAGIALN DNFVKLISWYDNEYGYSFRVIDLIVHMFGVDNEDLATAILKKKEKPNRLIVEEAPNDDNS VVSLSQAKMDELQLFRGDTVMLKGKRRKDTVCIVLSDDTVADDKIKINRCVRNNLRIRLG DIVSIQACPDVKYGKRVHVLPIDDTVEGLTGNLFEVYLKPYFLEAYRPLRKGDIFLARGG MRAVEFKVIETDPSPYCIVAPDTVIHCEGEPVKREEEEEQLNEVGYDDIGGCRKQLAQIK EMVELPLRHPQLFKAIGIKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSK LAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQ RSHVIVMAATNRPNSIDTALRRFGRFDREIDIGIPDATGRLEILRIHTKNMKLHEDVDLE QVAADTHGHVGADLAALCSEAALQQIREKMDLIDLEDDNIDAEVLDSLAVTMENFRWALS KSSPSALRETTVEVPSVTWEDIGGLENVKKELQELVQYPVEHPDKFLKFGMTPSKGVLFY GPPGCGKTLLAKAIANECQANFISIKGPELLSMWFGESESNIRDIFDKARSAAPCVLFFD ELDSIAKARGGNVGDGGGAADRVINQLLTEMDGMGAKKNVFIIGATNRPDIIDPAILRPG RLDQLIYIPLPDEGSRNAILKAALRKSPVSQDCDLNFLAKNTQGFSGADLTEICQRACKL AIRECIETEIKRERERG--PEDYDPVPEIRRDHFEEAMKFARRSVTDNDIRKYEMFAQTL QQSRGFGTKAKKMFGTTG-FGGTTNHNPMKDIEVTSPPDDSVSCLSFSPGTLPSTFLIAG SWDNNVRCWEVQQNGNTVPKAQQTHQGPVLDVAWSDDGTKVYTASADKTAKVWDLASNQA MQVAQHDAPIKTVHWVKAPSYSCVMTSSWDKTLKFWDTRTPNPIMTINLPDRAYCADVLY PMAVVSTAKRHIIIYQLENQPSEFKKVDSPLKYQHRCVSIFTDRKTSQPTGFALGSIEGR VAIQYVSPTNPKDNFTFKCHRNGCQDIYAVNCISFHPTHGTLATVGSDGRFSFWDKDART KLKTSEALDQPISASAFNATGTIFAYAASYDWSKGHEGYDPTKMKPHIFLRSCFDELKPS KK-MSSPSPGKRRMDTDVVKLIESKHEVTILGGLNEFIVKFIGPSGTPYEGGVWNVRVDL PDKYPFKSPSIGFVNRIFHPNIDESSGTVCLDVINQAWTALYDLSNIFDSFLPQLLSYPN PVDPLNGDAAAMYLHKPEDYKKKVKDYVSKYATEEAIRNQESSLSDFSEDETQDMEL--- ------------------------------------------------------------ -----------------------------------KLDNWLNELETFSTKHEIVKMLVGN KIDKDNRDVSREEGLKFARKHHMLFIEASAKTKEGVQCAFEELVEKIIQTPGLWETDKID ITDVIWSIINGSFCSHKVLTKTQKFCRNEYNVTGLCNRNSCPLANSQYATIREEKGIIYL YMKTVERAAFPNKLWEKVKLNRNFEKALKQIDEHLIYWPKWIIHKC-------------- ------------------------------------------------------------ ---------------------------------------VQQARYQAAPRMKKFQIYRWN PDKPGDKPHTDTFEVDLNRCGPMVLDALIKIKDTDDPTLTFRRSCREGICGSCAMNIGGT NTLACLARIDTNLSKTTKIYPLPHMYVVKDLVPDMSNFYAQYRAIEPYLKKKNMKEEDIG KESYLQSPEDRAKLDGLYECILCACCSTSCPSYWWNGDRYLGPAVLMQAYRWLIDSRDDY TVERMNAMEDKFSVFRCHTIMNCTKTCPKGLNPGRAIGEIKKML-----------ENRPN HTIYINNLNEKIKKDELKKSLYAIFSQFGQILDIVALKNLKMRGQAFVIFKEISSATAAL RSMQGFPFYDKPMRINYSKKDSDVISKIKGTFVERPKRPREEEKKKKKVPAQPAMIPEQA PNQILFLTNLPEETTEVMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENEIQSKAAKDALQ GFKITPTNAMKIAFAKKMDKDGRKVIVCDNGTGFVKCGIAGSNFPSHIFQSMVGRPVLRS TAKIGNIEVKDLMVGEECSQLRSMLEVTYPMDNGVVRNWEDMLHVWDHTFGPDKLNINPR DCKILLTEPPMNPMKNREKMIEVMFEKYQFAGCYIAIQAVLTLYAQGLLTGVVVDSGDGV THICPVYEGFALPHLTRRLDIAGRDITKYLIKLLLLRGYNFNHSADFETVRMMKEALAYV AYDVEQEQRLARETTVLVENYTLPDGRVIKVGGERFEAPEALFQPHLINVEGVGVAELLF NTIQAADIDTRPEFYKHIVLSGGSTMYPGLPSRLEREIKQLYLERVLKGDSAKLSKFKIR IEDPPRRKHMVFLGGAVLADIMKDKEDFWMTREEYEEKGLRVLERL--------GKPITC KAAVAWEAKKPLSIETIEVAPPKAGEVRIKVVANGVCHTDAYTLDGFDPEGKFPVVLGHE GGGIVESVGEGVTSVKPGDHVVPLYIPQCRDCKFCNNKKTNLCSKIRSTQGAGLMPDGTT RFTCNGKELFHFMGTSTFAEYTVVAEISVAKVDEKAPLDKVCLLGCGISTGYGAALNTAK VEEGSTCAIWGLGAVGLAVAMGCKVAGAKRIIGVDLNEDKFEVAKKFGCTEFVNPKKYDK PIQQVMCDLTDGGCDYTFECVGNIHTMRAALESCHKGWGESIIIGVAAAGAEISTRPFQL VTGRVWKGSAFGGWKSRDSVPKLVEDYTAKKLMIDEFITHNLPLNDVNKAFDLMHKGESM DGYDVIANQPVVIDNGSGIIKAGFAGDQVPKYHFPNYIGRPKHVRVMAGALEGDVFLGPK AEEHRGLLSIRYPMEHGIVRDWNDMERIWQYIYSKDQLQTFSEEHPVLLTEAPLNPRRNR EKAAEIFFETFNVPALFVSMQAVLSLYATGRTTGVVLDAGDGVTHAVPIYEGFAMPHSIM RVDIAGRDVSRYLQLLLRKEGCNFTTSAELEIVRTIKERACYLAINPQREETVETEKVAY TLPDGSVLDVGPSRFRAPELLFRPDLIGEECVGIHEVLLYAIQKSDMDLRRTLYSNIVLS GGSTLFKGFGDRLLSEAKKLAPKDIKLRISAPQERLYSTWIGGSILASLDTFKKMWVSKR EYDDEGVRAVHRKTFDPKKISKVVVHPLVLLSVVDHFNRMGKVGNMKRVVGVLLGSNRQG ILDVSNSFAVPFDEDDKDRSVWFLDHDYLENMYGMFKKVNAKEKIVGWYHTGPKLHPNDV NINEVIRRYCPNSVLVIIDAKPKALGLPTEGYIAVEEVHDDGTPTTKTFEHVPSEIGAEE AEEVGVEHLLRDIKDTTVGTLSQRVTDQLLGLKGLNSKINDIHSYLDQVTQKKLPINHQI VYHLQDIFNLLPDVNLEEFVKSVYVKTNDQMLVVYLASLIRSIVALHNLINNKIQNRDTE KNEGKDKKMGVLLSRIWSLFSNEEHKVIIVGLDNAGKTTILYQFLMNEVVHTSPTIGSNV EEVVWKNFHFLMWDIGGQESLRSSWHTYYTNAEVVIIVIDSTDRERLPITKEELTKILSN DELKKAKVLIFANKQDIKGAMTASEISQHLKLTTIKDHAWHIQACCALTGEGLYQGLEWI ANRLKRRSIPIRTVQLRQGDQLPHDYSTTPGGTMFSTTPGGTRIIYDRSFLLQCRNSPLT KSPPANLPNIPGVTK--------------------------------------------- ------------------------------WIPDTKGVYLDLVATSGDYLRVWRVTRLEC LLNNNKNSDFCAPLTSFDWNEVDPNLLGTSSIDTTCTIWGLETGQVIGIVSGHVKTQLIA HDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHQPLLRLAWNKQ DPNYLATMAMDSNEVIILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQAL IWDIQQMPRAIEDPILAYSGAGEINQIQWSATQPDWIAISYNNCLEILRV--FSTSRKVA VMGASGGIGQPMSLLMKQSPLISHLALYDIAHTPGVAADLSHIETKAKVTGHLGPDQLKD CLTGCDVVVIPAGVPRKPGMTRDDLFNTNASIVAALSDAAAQYCPKAMMCIISNPVNSTV PICSEIFKARGVYDPARIFGVTTLDVVRANTFIAEAKGLDVSKVNVPVVGGHAGVTIIPL ISLCTPPVSFPQAEREKMTVRIQNAGTEVVEAKAGAGSATLSMAYAGARFTFQVLEALNG KEGVVECSYVKSNETEASYFSTPLLLGKNGVEKDLGMGKIIEYEVGLVNGAMTELKSSIK KGEDF----IDRGKDFNIKTRIISDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFVS TLSHLRRLNSPIGRDGKLARPRQLHNSLWGMICPAETPEGAAVGLVKNLALMAYISVGSQ PSPILEFLEEWSMENLEEIAPSAICESTKIFVNGCWVGIHRDPEQLMSTLKKLRRQMDII VSEVSMIRDIREREIRIYTDAGRICRPLLIVENQKLLLKKSHIDLLKDKEYNNYSWQELV ASGVVEYIDTLEEETVMLAMTPDDLQEKGMAYCSTYTHCEIHPAMILGVCASIIPFPDHN QSPRNTYQSAMGKQAMGVYVTNFHVRMDTLGNVLWYAQKPLTTTRSMEYLRFRELPAGIN SIVAIASYTGYNQEDSVILNESAVDRGFFRSVFFRSYKDQESKKGLDQEEIFEKPTREKV QGMKPSCYDKLEDDGIISPGIRVSGDDCVVGKTMTIPENDDELEATARRFSKRDCSVFMR RTEYGIIDQVMVTINQEGFKFCKIRVRTTKTPQIGDKFASRHGQKGTCGIRYRQEDMPFT CEGITPDIIINPHAIPSRMTIGHLIECLLGKVSANKGEIGDATPFNDTVNVQKVSTYLQE YGYHLRGNEVLFNGHTGRKMNAQIFLGPTYYQR--------------------------- ------------------------------------------------------------ ----------------------------------------LPGGFQFDNCRRNALLEKGF KAPKALKTGTTICGVVFKDGVVLGADTRATEDTVVADKNCAKIHYIADNIYCCGAGTAAD TEMTTQMISSKIELHRLDTGRVPRVATACRMLKQKLFRYHGYISAACVLGGVDSTGPHLY SVWPHGSTDKLPYVTMGSGSLAAMAVFESGYTMDMNRDEAVLLVRNAIAAGIFNDLGSGS HVDVCVITKKVDYIRPYDIANKKGQKQGSYRYKKGTTATIKTEVKKIEYDVI-------- -----------------------------------------------------------L KHGSELRLIPRDRVG-MAFTFTAFAYILALILTAFLIFFAIYHIISFDELKTDYKNPIDQ CNALNPLVLPEYFIHILYNVLFVISSQWITLLLNMPLIVYHINRYRNRPVMSCPGLYDPT TIMNADQLSRCMREGWIKLAFYLLSFFYYLYSMIYVLVSTMGLLTILKKMKQKEKEIRLL ILGLDNAGKTTILKKFNGEDIDTISPTLGFNIKTLEHRGFKLNFWDVGGQKSLRSYWRNY FESTDGLVWVVDSADRRRLEDCRKELEALLVEERLAGATLMVFANKQDLPGALSAEDIKN ELNLDNIKTHHWLILGCSAVTGQNLLQGIDWIVSDIASRIFTMDHSKKKICYYYDGDIGN YYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATQEEMTKFHSDDYIKFLRSIRP DNMSEYNKQMQRFNVGEDCPVFDGLYEFCQLSTGGSIAAAVKLNKQAADIAVNWAGGLHH AKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY GEYFPGTGDLKDIGAGKGKYYAVNFPLRDGIDDDSYESIFVPVMTKVFETYQPNAVVLQC GADSLSGDRLGCFNLTLKGHGKCVEFVKKYNLPLLLLGGGGYTIRNVARCWTYETSIALN VDVANELPYNDYFEYYGPDFKLHISPSNMANQNTPEYLDKIRTRLFENLRMLPHAPGVQM SNIPEDALNDDVNPEERIPIRASDKHIQNEEEYSDSEDEGD-GRRDRQSFKRKKLTDSNF ECNICLDTAKDAVISMCGHLFCWPCLHQWLETRPQRQVCPVCKAGISREKVIPLYGRGNN SQQDPRDKVP-----------------GFNFGFQVSFGIGAFPFGIFTSSFNMGDGRPPA PQAGTPQYDEEQFLSKIFLWIAILFIVWLLIAMYSIIHKKEQAHDDSIWSCAWGRSDKDG SENIVTGSVDDTVKVWKWXNLELRHVLEGHQLGVLSVDINHSGTLCASTSLDSHIRLWDL ESGKQVKSFDAGPVDAWTLCFSPDSRFLATGSHTGKINLFGIESGKKETSIDAKMKFTLS VAYSPDGKYIACGSIEGIINIFDMTTGKLLEGHAMPVRSLCFSPDSQLLVTASDDCHIKI YDIQHGNLAGSLSGHGSWVLNVSFSPDNTHIVSSSSDKTVKVWDISSRSCSHTFYEHLDQ VWSAKYNYSGNRVVSVSDDKAVHIYDIP-ESAEDFDNRYEAYFNRPNIDGWELRKALNDI QGYDLVPEPRIVIAALKACRRVNDHSLAVRMLEAIQDKCGNRKKEIWPYVLSEITPTLKE LGISTPEELGYDKPELAQQDVYDM------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TYQSATGFWVHMRGLPFQAHEQDVCDFFRPLNPVHVEIH FNRGRASGEADVDFTSSDEAKEAMKKNRDKMQHRYIELFYQDKDKPSQIRDSNITAAKAV SDAIRTSLGPRGMDKMIQTGSGDVTITNDGATILKQMQVLHPAAKMLVELSKAQDVEAGD GTTSVVVIAGSLLDASSKLLHKGIHPMAISDAFQKASLKCCEILESMSTRVELSDHDSLL KSASTSLNSKVVSQYSSILSPITVDAVMKVIDPSSAHNVDLKDIKVVKKLGGTVEDTELV DGLVLDAKAAASEGPKKIEKAKIGLIQFCLSPPKTDMENEVIISDYTQMDRVLREERQYI LNLVKQIKKAGCNVLLIQKSILRDAINDLALHFLSKMKILVVKDVEREDIEFICKTLACK PIASIDHFTPEMLGSADLVEEVQAGSSKIVKVTGIQNKGKTVSLVVRGSNKLVLEEAARS IHDALCVIRCLVKKRALIAGGGAPEIELSIRLMEYSNTVTGMEQYCMRAFADALEIIPFT LAENAGLNPIATVTELRNRHAQGEKTAGINVRKGAITNILEENVVQPLLVSTSAISLAAE TVRSIMKIDDIV---MILLEIENRIVQETLQSAFSNVLNGGKPGSVDVTVADFDGVMYHI SNPKDDKTKIMVSISLKFFKDLQEH---------------------------EKNVPPNH EEVVKKAALLKRNCFASVFEKYFELQQKNKRAVINYRDDETLYIEAKNDRVTVIFSTVFK DDDDVVIGKIFMEEFKECRRQYQQAPQVIFSHKDPPSELAGTDARTGDNIGYITFVLFPR HENRDNTINLIHTFRNYLHYHIKCSKVYIHSHMRAKTSYFLKVLNRAKQVPQVKEKKTM- ------------------------------------VSHKKYPQLKEVDDVLGGSAAWEN VDSTAETCPKCSHPRAYFMQIQTRSADEPMTTFYKCCNMQCGNLWR------LKDEDRIF TNLYGRHDWRLKGAQARGDWYKTKEIVNKGHEWILKQIVTSGLRGRGGAGFPSGMKWGFM NKPSDGRPKYLVVNADEGEPGTCKDREIMRHDPHKLVEGCLVAGRAMGARAAYIYIRGEF YNEASNMQLAINEAYDAGLIGKNSCGTGYDFDVYMHRGAGAYICGEETSLIESLEGKTGK PRLKPPFPADIGVFGCPTTVANVETVAVAPTICRRGGEWFASFGRGSSTTVLMDFDALVQ AQTGLGTAAIIVMNRQSDLVRCIARLIEFYKHESCGQCTPCREGVGWMNKVMQRWTHGNG RPEEIDMLWEISKQIEGHTICALGDGAAWPVQGLIRHFRPMLEQKLEGFREK-XXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXDEPYYCSQQINIPPALPDILKQFTKAAIRTQPKDVLGWAAAYFRAMSKGEVPP VKERLEMPVATQKTDTGLTPGLLKVLHKQLGPKKVLEIDDVEERWSDLALPKERFDELVR IGNFAGDIEWLKFFCLAASTLGEGLAETMKLVCEVLTSDPEGGAARIPFTLWVDLYKYLA DIDGAIPQSQVDDVCAHLQYDVEKQDGFIQPRNFMSADCPKLSGQLDSAQKGALMDQVKQ QIALANAQELLQKMTDKCFKKCVYKPGTSLDNSEQKCIAMCMDRYMDAWNLVSRAYSQRL QRERGRMMNRLFGRAKPKGPPPNLNDCISGIDSRGESIDKKISRLDAELMKYKDQMKKMR DGPSKNMVKQKAMRVLKQKKMYEQQREQLSNQSFNLEQSNFAIQTVKDTKTTVDAMKIAS KEFKKEYKNINIDKIEDIQDELEDLTEQANDIQEIMGRSYGMPEVDDDELEAELDALGDD LALDEDTSYLDDAVNTPNVPTNVPGADSVASQDGIPVDEFGLPQM----TPMTPATPASP QLQNIVCTVNLGCKLDLKRIALHARNAEYNPKRFAAVIMRIRDPRTTALIFSSGKMVCTG AKSEDQAKLAARKYARIVQKLGFQAKFLDFKIQNMVGSCDVKFPIRLEGLVLRHAQFSSY EPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKVRQEIYDAFNNIYPILKGFKK-SEDED DDFVEFA--PEPGTKSDIEEFNFQVLSPEEIVQHMVDCIKEVNLIVEIPATTTRILLNHF KWDKEKLLERYWDGDQDKLFADAHVISPYKKGKEYFCEICFLSFQSLMAGLECGHKFCSH CWQEYLTTKIMDEGMGQTISCAAHGCDILVDDATVMKIITDSRVRLKYQHLITNSFVECN RLMRWCPAPDCQNAIKVGHYDPKPVTCSCGYIFCFACGESWHEPVRCKWLKKWIKKCDDD SETSNWIAANTKECPKCHVTIEKDGGCNHMVCQHCKADFCWVCLGPWEPHGSSWYNCNRY DEDDAKKARDAQERSRAALQRYLFYCNRYLNHMQSLKFEHKLYASVRVKMEEMQHHNMSW IEVQFLKKAVDILCLCRQTLMYTYVFAFYLKKNNQSIIFEDNQKDLENATEQLSEYLERE ITLDMLADIKQKVQDKYRYCDSRRNVLLKHVLEGYDKDLWDYQE---------------- ------------------------------------------------------------ ------------------------------------------------TEKVYDACMEAF DCLPLAALMNQQFICVHGGLSPEIHTLDDIRKLDRFKEPPAFGPMCDLLWSDPLEDFGSE KTQDHFTHNSVRGCSYFYSYAACCEFLQQNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSL ITMFSAPNYLDVYNNKAAILKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVT EMLVNVLNICSDDELVND------GTVAARKEVIRNKIRAIGKMARVFTVLREESESVLQ LKGLTPNGLLPLGALSGGKDTLKSTLSGFSPNHKISGFEEAKCLDKMNERIPPRK---PE GGGGFGGRGGRGGGDRGGFGRGR----GGRGGMRGGRKVSVEAHRHEGVFVARGKEDALV TLNLVPGNTVYGEKKIAVEEGVKKEYRAWNPFRSKLAAAILGGVDHIHIKPGKKVLYLGA ASGTTVSHVSDIVGPDGIVYAVEFSHRSGRDLINVAKTRTNIVPIIEDARHPHKYRMLVG MVDVIFADVAQPDQARIVAINAHNFLKNGGHVVISIKANCIDSTAAPEAVFQGEVNKLKE EKIKPTEQLTLEPYERDHAVVVGIYRPP-------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------QERQQKVVQAQGEAEAAKLLGQAISINPAYLKLRKIRAAQNIARTVSQSQN RVYLSGQSLMLNLNDASFDDNLKSYTGSSSDEDDVNPREKIQKNSKGSSDFCVRIQQHAY GRREIEIAEQEMPGLMALRKRAQDDKPLEGAKICGCTHITAQTAVLIETLVSLGAQVRWA ACNIYSTQNEVAAALAEAGYSLYSWKGETEDDFWWAIDKCINSDNWQPNMILDDGGDLTH YMLKKYSTTFSMLKGIVEESVTGVHRLYQLSKAGKLTVPAMNVNDSVTKTKFDNLYSCRE SILDALKRTTDVMFGGKQVLVCGYGEVGKGCCAALKGLGAIVMVTEIDPICALQACMDGF RVVKMNEVVKQVDVLITCTGNKNVVSREHLDRLKNGCIVCNMGHSNTEIDVGSLRTPELT WEKVRSQVDHIIWPDGKRIVLLAEGRLVNLSCSSVPSFVVSITASTQALALIELFNAPPG RYKQDVYLLPKKMDEYVASLHLPTFDAHLTELSDEQAKYLGLSKAGPFKPNYYRYPDPDC IKMFVGQIPRSMDETDLRKMFEEYGPIYQITVLRDKATGQSKGCCFITYYTRQDSVNAQR DLHNLKTLPGMQHPIQMKPADSEKRN-EERKLFVGMVSKKCAENDIRVLFAPFGNIEECT ILRE-NGQSKGCAFVTYTSKQSAHNAMKALHHSQTME----------------------- ------------------------------------------------------------ -------------------------EAAFFAAIALTPTELVKCKLQAIVKHILRTEGIRG MFRGFVPTVAREMPGYFVFFGSYEFSRRMLTPEGKGPEDIGVKTILCGGIGGAMLWISVF PTDVIKSRAQIKEDGFLALYKGLGPTVVRSFISSG--------------DSQSEYSRLTA NISSNIQKITNNVSQVQRMSNQIGTPSDSEKLREELHQIEHYTNQLAKETNGLLKEVTRL ASEQRQKKLQMERFTDDFTAALNKFQHSLRHAAQKEKDSVEDVNLELIKEREEAIRKLEA DIVGVNDIFKELGMLVHEQGEVIDSIEANIESIHVQEGGQQLEKARDYQTSARKKKCILL IIGVVILVVVIIILAVVLSMVNVMKGVLIECDPAMKQFLLHLDDTNALGKKFIIQDLDER HLFVSADILETLNTKIDGLMDSLSYPLGNKKGKAPTPQEAIQRLRDVEEMLEKKSAFLEK KIEEQTAIARKRVALNALKKKKAYDKQLNNIDGTLSTIEFQRQSLENASTNTEVLKVMGV AADALKGAHQGLDVDKVHDIMDDIAEQHDISQEISEAISNPMGFNQDIDEDELNAELEEL EQETLDDQLLKVNDLPTVPSAEDADLRELEAWASSMQRFHNRVRQILMASGSTTFTKIVN KWNTALIGLMTYFREAVVNTQELLDLLVKCENKIQTRIKIGLNSKMPSRFPPVVFYTPKE LGGLGMLSMGHVLIPQSDLRWSKQTDVGITHFRSGMSHDEDQLIPNLYRYIMPWESEFID SQRVWAEYALRTDMIQALGGVEGILEHTLFKGTYFPTWEGLFWEKASGFEESMKYKKLTN ASKDVMDNTTTQKFWIDVQLRWGDYDSHDIERYARAKFLDYTTDNMSIYPSPTGVLIAID LAYNLHSAYGNWFPGCKPLIQQAMAKIMKANPALYVLRERIRKGLQLYSSEPTEPYLSSQ NYGELFSNQIIWFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIYTSV WAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKG SELQLPFQACLKVEKFGDLILKATEPQMLLFNLYDDWLKTISSFTAFSRLILILRALHVN TDRTKVILKPDKTTITEPHHIWPTLSDEEWIKVEVQLKDLILADYGKKNNVNVASLTQSE IRDIILGMEISAPSAQRQQIAEIEKQTKEQSQLTATTTRTVNKHGDEIFSSTTSNYETST FSSKTEWRVRAISATNLHLRTNHIYVSSDDIKETGYTYILPKNVLKKFIVISDLRAQIAG YLYGVSPPDNPQVKEIRCIVMPPQWGNHQTVHLPNITPTHEYLKDMEPLGWIHTQPNELP QLSPQDISTHAKIMADNSGWDGEKTIIITCSFTPGSCSLTAYKLTPSGFEWGRQNTDKGN NPKGYLPSHYERVQMLLSDRFLGFFMVPGQSSWNYNFMGVRHKPNMKYDLALANPKEFYH EVHRPSHFLNFSSLEEGMDREDLFSIYSEARKNLMIGSKTKVICQGFTGKQGTFHSQQAI EYGTRMVGGVSPGKGGSTHLDLPVFNSVAEAKAETEADATVIYVPPPFAAAAILEAIEAE IPLIVTITEGIPQQDMVKVKHSLLRQNKSRLVGPNCPGIIKPGECKIGIMPGHIHQRGCI GIVSRSGTLTYEAVHQTTQAGLGQTLCVGIGGDPFNGTNFVDCLDVFLKDPETKGIVMIG EIGGAAEERASEFLQEHNGKNAKPVVSFIAGVTAPPGRRMGHAGAIIAGGKGGAEDKIAA LRGAGVSVTMSPAQMGTTMRKEMEKRG-LPSEALRCTLCHERLEDTHFVQCPSAAEHKFC FPCSRESIKRQGAGGEVYCPSGKKCPLLGSNVPWAFMQGEIATILGXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-X CPFLLRVFCNTNRHHDMREFSRDQTPKNELQIYTWKDATLKELAGLVREVNPDARKKGTY FDFAIVQPDLRTPYMRLREIGTVVGGRKGNDDSVCLKAKKFVIGDYIDISISPPRGLGKT LQTISLLGYMKHHRNVPSPHLVIVPKSTISNWMNEFKRWCPTIKTVCLIGDQIARAALVR DVILPGDWDVCVTSYEMVIREKSVIKKFNWRYIVIDEAHRIKNEKSKLSEIVREFKSTNR LLLTGTPLQNNLHELWALLNFLLPDVFNSADDFDSWFSTNDCLDNDVIVKRLHNVLRPFL LRRIKSDVEKSLLPKKETKIYIGLSKMQREWYTRILMKDIDCVNGAGKTDKMRLLNILMQ LRKCCNHPYLFDGAEPGPPYTTDTHLFENCGKMVLLDKLLPKLQSQGSRVLIFSQMTRML DILEDYCGWRGFEYCRLDGQTPHEQRQESINEYNMPGSSKFVFMLSTRAGGLGINLATAD IVIIYDSDWNPQVDLQAQDRAHRIGQKKQVRVFRFITENTVEERIVERAEMKLKLDNIVI QQGRLVDAAHNKEVLNMIRHGADHVFAAKDSTITDADIDTILEEGEKRTEEMKKKLEVMG ESTLQSFSFDTEEGSLYKFEGEDYRDKQKLGGLSHWIEPPKRERKANYAVDAYFRDALRV SEPKAPKAPRPPKQPNIQDYQFFPPRLFELLDKEIYYYRKTIGYKVPRNPELGADADRVR KEEQRKIDDSERLNEDEEAEKEDLLKGFTTWSKRDFQQFIKANEKFGRDDIESISKEVEG KLPEEVINYSAVFWDRCSELQDIEKIMAQIERGEARIQRRSSIKRALDNKIARYRAPFHQ LRIQYGTNKGKNYTEEEDRFLVCMLHKLGFDKENVYDELRASVRQAPQFRFDWFIKSRTA MELQRRCNTLITLIEREVQEIEEKEKAERKKDIPTSWADQVEEGEHRELPTPKEEYDEEN GIRTIIEYKYNEDNKKVKVVKTYKVEKRKVSKSIARRKSWKKFGLAENDPPGPNPANTIE DIFMQFVHNKEAPEDEALSKLKVSCRICKGDHWTTKCPYKDTLTPLAEALGGGSKYIPPS LRGGSKGRGESMSMDEAATIRVTNLSEETRESDLQELFKPFGAISRIYLAKDRYTGASKG FAFVSFHRREDASRAIQGVSGYGYDHLILNVEWAKPSMSETYDFLFKFLIIGSAGTGKSC ILHHFIENKFKQDSNHTIGVEFGSKIVNVGGKSVKLQIWDTAGQERFRSVTRSYYRGAAG ALLVYDITSRETYNALTNWLTDARTLASPNIVIILVGNKKDLEDEREVTFLEASRFAQEN ELMFLETSALTGENVEETFLKCARSILTKIESGELDPERMGSGIQYGDASLRRL------ ---LVAPSDEQKLDTSQWPLLLKNFDKLNIRTNHYTPIPNGNSPLKRPIDEYIKTGVINL DKPANPSSHEVVAWIKRILRVDKTGHSGTLDPKVTGCLIVCVGRATRLVKSQQGAGKEYV CIFKLHSAVEDQKKILQAVETLKGALFQRPPLISAVKRQLRVRTIYESKLLEYDDDKNMG ILWISCEAGTYIRTLCVHLGLMLGVGGQMQELRRVRSGIHSEKDGLVTMHDILDAQWLYD NQKDESYLRRVIRPLESLLVSHKRVILKDSAVNAVCYGAKIMLPGVLRYEDGIEINEEIV IVTTKGEAIAIALALMTTAVMATVDHGCVAKIKRVIMERDTYPRKWGLGPVASQKKAMIK EGLLDKYGKKNDKTPADWVKSYKDFNGVIKRKHESPSKSEKKKKHKKKMAEADWDRKAPK NNTTLKSAADVRTAQRQGLDVETTKKFSASQNRQHTANKDTARLDRETEELHHDHVEISV SKLIQQKRAELGMTQKELATKINEKPQVINEYESGRAIPNQAILTKIERSLGVKLRGKDK GQPLFKKMLKPKALTQILNQANTDGVQYSLLLNGEGALLAFSGYGDKDARVTAAIASGIW AAYEKGGAIAFNEDRLKIVLLDCQEGKVAITKVSNLLLCIYATDEVGFGMLKAKAKALSE YLEGPLTQVASSTAATARINNKKQTLEDAYSPPANFLEIDICDAQLKKRYTDYEVRMRTN LPVFKLKESSVRRRYSDFEWLRNELERDSKIVVPQLPGKAFKRQLPFRGDEGIFEAEFIE DRRKGLEGFINKVAGHPLAQNERCLHMFLQEPVIDKNYTPGKVRNT-------------- ----------------KVFGYRGIVLFPWLARVYDRDQSSIGTPEVQSRTHTYYQVLIDA RDCPFIRAQSEGVMFLGNQENRSLYAIPGLDYVAHEDVLPYTSTEKQPIDHELFDRFLIY DPPFIARETLRAWQEKNHPWLELSDVHRETTENIRVTVTPFYMGESQESKVYWWRYCVRL ENLGLDPIQLRERHWRIFSLSGTLETVRGRGVVGQEVLLSKQSPAFQYSSHVSLQAPSGH MWGTFKMEKQDGSHFECRIPPFCLESKQDNS----------------------------- ---------------------PFCVFRWNPGARMRFKKTEVCQTCARLKNICQTCLLDLE YGLPVQVRDTALKLTNDIPRSDVNKEYFSQNVE----------TYGQLGKAQAPSDMLLK LARTTPYYKRNRPHICSFWVKGECKRGEECPYRHDKPTDPEDPLADQN------------ -------------------MDVFLMIRRKKVTIFADAKESTTVLDLKKIVEGILKTSPED QMLYKDNKTLADCGYTSQTARAQAPALVGLAFKKFECLDITSLSTPPELPDVMKAQDNSS SHSQEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMENFSKIEKIG EGTYGVVYKAKDKTSGRIVALKKIRLDTESEGVPSTAIREISLLKELDHINIVRLLDVIH SEKKLYLVFEFLNLDLKKFMDSSPPSG-IPSALVKSYLKQLLEGISYCHTHRVLHRDLKP QNLLIDTEGNIKLADFGLARAFGVPVRSYTHEVVTLWYRAPEILLGARFYSTAIDVWSIG CIFAEMITRRALFQGDSEIDQLYRIFRKLGTPDERVWPG--------------------- ------------------------------------LFNTLGRIGVGVAVAGGVVQSALY NVDGGHRAIIFDRFRGVQDKVIGEGTHFFIPWVQKPIIFDCRSRPRNVPVITGTKDLQNV NITLRILFRPAVNSLPNIFTNLGPDYDERVLPSITTEVLKAIVAQFDASDLITQREIASQ RVSEALRERGASFGLIMDDISLTHLTFGREFSEAVEQKQVAQQEAERARYVVEKAEQQKI ATVTSAEGDTIAAELLAKSIGDAGEGLIELRKLEAAEDIAYQLARSRNVVYLPSDQKTLL SLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXMGCAVSTDDRAAVERSKQIDKTLRADGEKAAREVKLLLLGAGESGKSTI VKQMKIIHEKGYSKDECLQYRPVVYSNTIQSMIAIIRAMGQLKIDFGQESRAEDARQLFL LAGNADDGELTPELAETMKRLWKDSGVQHCFGRSREYQLNDSAAYYLNELDRISMPEYVP TEQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFIVAMSE YDLTLAEDQEMNRMMESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIRSSPLTICFPD FTGSNTYEEAASYIQLQFNKKKDTKEIYTHFTCATDTNNVQFVFDAVTDVIIKNNLKDCG LFKKYAVQKTIINLKDSRLKPKDRAKKKRKKADPQNMKIRELPQASSAMFFKYNTQLGPP YHVLIDTNFVNFAIKNKLDIVQSMMDCLYAKCIPYVTDCVMGELERMGSKYRVALRIVKD PRFKRLTCFHKGIYADDCIVQRITEAKCYIVATCDKDLRRRIRKIPGVPIMYLADRRFSI ERMPDAFGAPKMSFSSDEVNFLVYRYLQESGFAHSAYTFGIESHISQSNINGALVPPAAL LSIIQKGLQYTEAEISIGEDGSERVIDSLSLIDAVMPDVVESRKQAAQK----------- ----NIEIPPSKATVLRGHESEVFICAWNPTTDLLASGSGDSTARIWNLNDNSNANQLVL RHCIQKGGTEVPSNKDVTSLDWNCDGTLLATGSYDGFARIWSTDGRLVSTLGQHKGPIFA LKWNKKGNYILSAGVDKTTIIWDASSGHCTQQFAFHSAPALDVDWQSNNSFASCSTDQCI HVCKHGADKPIKTFQGHTNEVNAIKWDPQGNLLASCSDDMTLKIWSMKQDTCVHDLQAHN KEIYTIKWSPTGPGTNNPNAPLILASASFDSTVRLWDVERGVCIHTLKNHQEPVYSVAFS PDGKYLASGSFDKCVHIWNVHSGALVHSYRGTGGIFEVCWNYRGDKVGASASDGSVFVLD LRK--NDLASLFECPVCFDFALPPIMQCQSGHIVCSSCRPKLSSCPTCRGALGNIRNLAM EKVASTVSFPCKYSTSGCPISLLHTDKAEHEDACEFRPYTCPCPGATCKWQGSLEQVMPH LMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKVD-VQMFYA IVQLIGTRKQAENFFYKLELNGHRRRLTWEATPRSIHDGIQSAIANSDCLMFDTNIAQLF ADNGNLGINVTIS-----QTLYQEYLQMPPITRAYTSACLLTTLLVQLDFLTPFHLYFNP ELIFYKYQIWRLITNFTFFGTFGFNFFFNMIFLYRYCRMLEEGSFRNRVADFVFMFFICA VLMSCVINIVFLGQAFTMMIVYVWSRRNMYVRMNFFGLMNFQAPYLAWVLLAFSWLLGNP ITIDLLGIAVGHIYFYLEDVFPNQQGGFRILKTPQLFKMLFDPVPEDPNYNALPPGGYNW G-GLDLLSAQGFRIDGRKTSELRRIQCRLDVFSQADGSAFIEQGNTKILCAVYGPHEVRG ARSKNDRALINCQFSMATFSTGERKRRPRGDRKSTEMTMHLRQTFEAAIMTERYPRSQID IFVEVLQSDGGNYCACVNAATLALVDAGIYMKDYVCACSSSYINDKSIVDINYMEESSGP EVIVATLPKSDHIVFLQMNGRMHEDYLERVLDTAVKGCKDIYSVLDRTVREMSGTYYFVI VGHFDNPVFEMEFIPPNKASEPKKEDHRHLNQFIAHAALDLVDEQMWASNNMYLKIVDKF NEWYVSAFVTAGRMRFLMLHDVKNEDGIKNFFTEMYETYIKHALNPFYEPYTPVKSVSFD RKAQFYARKYLPLQVRCAHTDVRVPDFSFYRRDDVKADRKAYTYMVLAGGGLAAGYGAKT IVTEFVSSMSASADVLAMAKIEIKLGEIPEGKNAVFKWRNKPLFVRHRTADEIEVEKGVN ISELRDPQHDDDRVKNPEWLILLGVCTHLGCVPIANSGDFGGYYCPCHGSHYDASGRIRK GPAPLNLEVPEYSFPDDDTLVVGMSRQANRFGDPRKVSAELFTLTYGALVAQLLKDIEND DEVNKQLDKMGYNIGIRLIEDFLARSNVGRCHDFRETADVIAKVGFKMFLGITPSITNWS PAGDEFSLLLDNNPLTDFVELPEGHSTLNYSNILCGALRGALEMVQMDVDVRFLQDTLKG DNITEIRLKFIKRLEDAVPEGED---KQFLQQAKEEFEEKWSKPAQNTAGLDDFDRIKTL GTGSFGRVMLVQHKQSKEYYAMKILDKQKVVKLKQVEHTLNEKRILQAVNFPFLVRLEYH FKDNSNLYMVLEFVTGGEMFSHLRRIGRFSEAHSRFYAAQIVLTFEYLHHLDLVYRDLKP ENLLIDVQGYIKVTDFGFAKKVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVY EMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLKNLLQVDLTKRYGNLKNAVA DIKNHKWFATTDWIAIYQRKVEAPFIPKCKGPGDASNFDDYDEEPLRIATTEKCAKEFAD FMLADSLLIVFISICTALLGEGLTWLLVYRTEKYKKLKTTVDKQSKKLEKQKDTIGENAD RSSKKKLERQEEKLKINNRDLSMVKMKSMFAIGFAFTALL-------------------- ----------------------------------------------------------CT KHFDNWTESEQVDFVEHLLSRMCHLQLGEINAFLKPMLQRDFISALPAKGLDHLAEKILS YLDAQSLCAAELVCKEWQRVISEGMLWKRLIEHMVLTNEMWKGLSERNGWAKYIFRPKPG ESLQDHTYYRKMYPEILNNIQVIENNWRMGRHSLQRIMCRSETSKGVYCLQYDDQKIVSG LRDNTIKVWDRNSLECVQVLTGHTGSVLCLQYDQNIIVSGSSDSTVRVWDVRTGQMVNTL IHHCEAVLHLRFCDGIMVTCSKDRSIAVWDMQSPNDINLRRVLLGHRAAVNVVDFDEKYI VSASGDRTIKVWNTSSCEFVRTLNGHKRGIACLQYRDKLVVSGSSDNTIRLWDIECGVCL RILEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPAGSLCMRTLVEHTGRVF RLQFDEFQIVSSSHDDTILIWDFLNMAKTYDYLFKLLLIGDSGVGKTCILFRFSEDAFNS TFISTIGIDFKIRTIELDGKKIKLQ----------------------------------- --------------------------KCDVNERRQVSKERGEQLAVEYGIKFMETSAKSS VNVEDSFYTLARDIKSKMDRKM---ETNADKNVEMWKIKKLIKSLEAARGNGTSMISLII PPKDQISRVAKMLADEYGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVIYCGT IVTDEGKEKKVNIDFEPFRPINTSLYLCDNKFHTEALTALLADDNKFGFIVMDGNGALFG TLSGNTREVLHKFTVDLPKKHGRGGQSALRFARLRLEKRHNYVRKVAETAVQMYITNDRP NIAGLVLAGSADFKTELSQSDMFDPRLQAKIIKIVDVSYGGENGFNQAIELSADALSNVK FIQEKKLIGKYFDEISQDTGKYCFGVDDTLKALEMGAVETLIVWENLDITRYTLRNHTSD EDKVLNLRPEQEKDKTHFVDKETGVELELIDQQPLLEWFANNYKSFGATLEIITDKSQEG AQFVRGFGGIGGMLRYQVDFQSLE-VDELDDDFDLDDYITRCSQPLVGKKNSDDEKYIQM IMDANAQSHKLFIMDARPSVNAVANKAKGGGYESEDSYPNTELVFLDIHNIHVMRESLRK LKDVCFPNIDDNHWLTNIESTHWLEHIKQILAGAVKIADKVESNKSSVLIHCSDGWDRTA QLSSLSMMMLDPYYRSIRGFEVLIEKEWLSYGHKFALRIGHGEDKHTDADRSPVFLQFID CVWQMTRQFPHAFEFNEQFLITILDHLYSCLFGTFLYNTDSQRVKEEVKKKTVSLWSFIN SDIEEYTNPLYKYVILPVASMRRMELWTRYYIRWNPRMRPQEPIHLRNRELLNLKAQLMR KFEDLQRELDIKNQPFRTFIPHLPFDLTQCEMAFPRPKTAPEEKSFTDALLKRNTDLAQT TQEQASILALVTKISGVMDNLIVSPVGFDAAQIEEVRQVGSHKKGTMMTGHNVADLVVVL KTLPTLEAVQALGNKTLEDLKAAEPQEVLTMITNESGFEVSSPDATVKVLIATLPQNLKK LDPELHLDAKLLTRHLSAIRHARWFEENAFHSSIKVLIRLLRDLKTRFEGLEPLNPWIID LLAHYSIMNNPPRQPLAINLAFRRALQLIAAGFFLPGSVGITDPCEPNNVRVHTSMSLEQ QDQVCYTGQTLVRVLAHGGYRQILGIEGNLNIATEMSVWDGVVVTPSDKAYEK---XXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXX----------------PRLATFWRYAKVEMKPPREFGEVQ AGFGKLASLKTGAWKKVTVKEAACITAEIAFWFFVGEIIGRRSIVGYAIPGAVDYEPHDI PRFYYKLPSEDEVLLQKLREESRAVFLQRRSKELLDNEELQNLWLELDKHHTPPLVGDEQ MIKYDDFLKVRNLAGPKCRPFFTATVFSKLVQTDPYGRISIMQFFNYVMRKVWLHQTRIG LSLYDVAGQGYLKESDLENYILELIPTLPQLDCLEKSFYSFYVCTAVRKFFFFLDPLRTG RVRIQDILACSFLDDLLELRDEDLPKEQQEVNWFSAPSALRVYGQYLNLDRDHNGMLSKD ELARYGTGTLTNVFLERVFQECLTYDGEMDYKTYLDFVLALENRKEPQALQYLFRILDVE NKGFLTVFSLNYFFRAIQDQMVAHGQEPVSFEDVKDEIYDMVKPVDPLRISLQDLIASGQ GDTVISILIDLNGFWTYENREVEVVRGQNFEVGPRYANLSYIGEGAYGMVVSAYDSVTKQ KVAIKKISPFEHQTYCQRTLREIKILTRFKHENIIDIRDIIRAKTLEEMKDVYIVQCLME TDMYKLLKTQHLSNDHVCYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFG LARVADPGHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDVWSVGCILAEMISNRPIFP GKHYLDQLNHILGILGSPGQEDLQCIINEKARGYLQSLPFKPKIPWVKLADLKALDLLDK MLTFNPHKRITVEEALAHPYLEQYYDPQDEPVAEEPFTIDMEYDDLPKEKLKELIFEET- -----QLTPPKTTPEWVKFCKQLFGGFSLLLWIGAILCFIAYSIQASTSENPVGDNLYLG IVLTAVVVVTGVFSYYQESKSSKIMESFKNLVPQFACVIRGGDKTTVHAEDLVIGDVIEV KFGDRVPADIRVISAHGFKVDNSSLTGESEPQSRTADFTNDNPLETRNLAFFSTNAVEGT CRGVVVRTGDDTVMGRIANLASGLEMGETPIAREIAHFIHLITGVAVFLGVSFFIIAFIL GYNWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTI CSDKTGTLTQNRMTVAHMWYDNKISEADTSEDQTSATYNQGDSDWLVLARVAMLCNRAEF KGGEEDKPVLKRDCIGDASESALLKCVELSIGKVIEYRKSHAKVMEIPFNSANKYQVSIH TDG--YLLVMKGAPERILDRCSTILMNGKDIPLDAQWREAFNSAYMELGGLGERVLGFCD YILDKKDYPDGYPFDAEEQNFPLTGLRFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVT GDHPITAQAIAKGVGIISEGNETVDDIANRLNIPREEVNARDAKACVVHGSDLRDMTPAQ IDDILINHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIA GSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLLFIVFD IPLPLGTITILCIDLGTDMVPAISLAYEEAESDIMKRKPRDPQHDKLVNHRLIGMAYGQI GMIQAAAGFFTYFVIMCENGFWPSRLFGIRKEWDAMGINDLEDSYGQEWTYTQRKQLEYT CHTSFFVSIVIVQWADLIICKTRRNSLFQQGMKNHHLTFGLFFETALAAFLCYCPGLDKG LRMYPLRFTWWLPPLPFSLAIFIYDECRKYLLRRYGHGWLEDETYYTFKKLSAAKKLGVG LAVGGLGVGVALSELTLHPPKYPWDHSGPFSALDHASIRRGYQVYKNVCAACHSMNYLCY RNLVGVSHTEEEAKAEAAEVMVMDGPDDDGNMFERPGKLSDRFPKPYPNDEAARAANNGA LPPDLSYIVNARHGGEDYLFALLTGYADPPAGVNLRDGLHFQPYFPGQAIGMAQALYNEI IEYEDGTEASMSQLAKDVSVFMRWACEPEHDQRKRMFVKAIMFFAMAASFYYKKHKWTVL KARKLAFIHPGLPSKCTYKPD-KEKSPHTHQKRRSLILDNVSEYVGETPMVKLNKIPKEE SLECDIFVKCEYLNPGGSVKDRIAYRMVNDAFKNGTLKKGDTIIEPTSGNTGIGLAMMGA IYGLKVIIVMPEKMSMEKVATLRALGAEIVRTPTSASFDSPESHISVAQRLMDEINKAHI LDQYRNPSNPIAHYDGTAEEIWEQMDKKVDMIVCGAGTGGTVAGISRKIKELNPNCKIVA LDPNGSILAQPDECPFYEVEGIGYDFVPTVLDRKLIDRWYKCEDKSSFLMSRRLIRKEGL LCGGSSGAAMVTAIRAAKDFGLKNGQRVVVLLPDSIRNYMTKFLSDDWMEERGF------ ----------------------XHGKATLPNNDTYEGMYENGLRNGQGTYRFKNGSRYIG EYQKGKKHGQGTFIYPDGSKYEGNWVEDQRCSFGKYTYVNGDXYEGEWANNVRQGQGTYF FAETGSKYVGTWKEGRREGAGELVHANHKYIGSWKSDKVEGKGKYVFDIGCQQHGEY-XX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXSIDALRFHLAAANKKCLREEIHKDVLVSGEYELSDAPGQKTDL KVTDSKSHVLFSKEDASKGKFAFTTEEYDMFEVCFQSQMPGGGQGPEREVSIQLKHGVEA KNYENIAKAEKLKPMEVELRRLEDLSESIVNDFAYMRAREEEMRDTNESTHSRVLYFSVF SMCCLLGLATWQVLYLRRFFKAKKLIEEMESGRTSSVGNDILGFGGNVVNKPDHGHLDWT KICERASKVITFIDLAGHEKYLKTTVFGMTGHAPDFSMLMVGANAGIVGMCKEHLGLALA LNVPVFVVVTKIDMCPPNVLADTLKLLQKILKSPGCRKIPVLVQNEDDVIVSASNFVSER ICPIFQVSNVSGQNLPFLKMFMNLLSTRLKNEPAEFQIDDTFSVPGVGTVVSGTCLRGHI RLNDAMMLGPDALGQFQPIVVKSIHRKRMPVKEVRGGQTASFSLKKNQIRKGMVMLSPKL EPTACWEFDGEVLVLHHPTTISVRYQAMVHVGSVRQTATIISMSQEHLRTGDKANVRFRF IKNPEYLRTDMRLVFREGRTKAVGTIIGLHPHIPGNTRQMRANKKGQDQEKLANQENHHF YLFKVLRAHILPLTNVAFNKSGSSFITGSYDRTCKVWDTASGEELHTLEGHRNVVYAIAF NNPYGDKVATGSFDKTCKLWSAETGKCYYTFRGHTAEIVCLNFNPQSVVATGSMDTTAKL WDIICTFNGHSAEIISLTFNSTGNQVLTGSFDHTVSLWDQRCHTLIGHKAEISSAQFNWD CSLIATGSMDKTCRIWDPGYGRCIKELQGHEDEVLDVGFDYTGQYLLTASADRCYNTANH CRLLGHEGEISKITFNPQGTKILTASSDKTARLWNPETGECQQILEGHTDEIFSCAFNYE GNTIITGSKDNTCRIWRADVFLEKHWKSVIHRSICDYFFEAQGKAATPEDVPPVISTPHH YLINIHRNNLFFVAVVTTEVPPLFVVEFLHRVVDILEDYFEEANETIIKDNYVVVYEILD EMLDNGFPLATESNILKELIKPPNILRTLANTVTGKHSNVSATLPTGQLSNVPWRRTGVK YTNNEAYFDVIEEIDAIIDKSGSTVCAEIQGYIDCLIKLSGMPDLTLSFMNPRLLDDVSF HPCIRFKRWENEKVLSFIPPDGNFRLISYHIGANNLVQIPVYIRHNISFREGSAGRLDLT IGPKQTMGKTVEKVILEIPFPKSVLNVTLTATQGKYTFDPVTKIMMWDVGKIDVTKLPNI RGSITLQSGAPIPESNPTISMQFQISQLAISGIKVNRLDMYGE----------------- ----MATECKPAVKFTTGDWFTSNHAISSNAERQRGTSHTVRQQAHMLRNETDNKTKWDN YDNNT----------------XKVLGDLDKEIKDISESKDLAEDALEAKNLPLNVAIECQ TMRDGRNGIDLVNDEVENQLHKEVEVIEGAKKELQQKIDESFEQICLLQEARQQIVADLH DKNIALGIDIDQYNLTEKSPGISYKPDPLRVPK--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------C QQLLPTYQGGEEPLPEGLFWLLVTGKVPTQAEAESLSKEWAVRASIPQHVVQMLNGFPNT LHPMSQFSAAITALNTESKFAKAYADAVPKSTYWEYCYEDAMDLIAKLPTVAAIIYRNLY KDGT-ITAINPDKDWSGNFSDMLGFEDPDFSEMMRMYLTIHSDHEGGNVSAHTCHLVGSA LSDPYLSFAAAMNGLAGPLHGLANQEVLVWLTKIELGDEKIKKFIWETLKTG-VIPGYGH AVLRKTDPRYMCQREFALKHLGDDHMFQLVSQLYKHVPDILIEHGKAKNPWPNVDAHSGV LLRHFGLTEMNYYTVLFGVSRALGVMASLVWDRAHGLPIERPKSMSTDGLMKQV-XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXX--------------------TPENLKRAKAIIDNYPKGHEAAACLPVLDIA QRQNNWLPISAMHRVAELLGMSRMRVYEVATFYTM---EPVGKYFVQICTTTPCILGGCG SDVILETIQKNLGIKPGQTTKDKMFTLLEVECLGACVNAPMVQINDNYYEDLTPKDMDEI LNDIKAGKTPKAGPRNG---RFASEPLTGLTSLTEPP----------------------- ------------------------------------------------------------ -------------DLKKYFDSCNGEIDPDAVKSFMYQLLRGLGFCHSRNVLHRDLKPQNL LINKNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLY------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------KRQTRGGKGMVKAKKKSSPQKIAL FRASRGKKKFVTVVQGLGSNDIDVKDASKYFANKFSCGSSVTGEDEIVIQGDFKDELFDL ITDKWPSIDEDNIEDKGDMKRSYCADRSAQWSNMKHKLFGTLDGYSCVMYGSPLRWRSWF FFPPDKGGLNAVNPNGFSSVLVPDKHSLITDAGKLHVLDSLLMRLKSEGHRVLIYSQMTK MIDILEEYMFHKKHSFMRLDGSSKISDRRDMVADFQTRSDIFVFLLSTRAGGLGINLTAA DTVIFYDSDWNPTVDQQAMDRAHRLGQTRQVTVYRLICKGTIEERILERAKEKSEIQKMV ISSGHFRPDSLKPKEVVSLLMDDE-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXYYQSLPKVVKRRIKALKKLQNEQMLIEGKFYEEVHALECKYA DKYIPIFDKRKDFVSGHVEPNDDDCDWPSDEETEADKAKIEDEENPVGVPDFWLTIFKNV ELLADMVQEHDEPILRHLSDIKIKHHFGFTLEFFFTPNEYFSNTCLTKEYEMRMEPDPAD PFSYEGPEIIKCKGCPIDWKKSKNVTVKTIKKTQKHRGRGVKRTVTKQVQNDSFFNFFSP PQQPENELDEDTEALLSADFEIGHFIRERIVPRAVLYFTGEALDEEDEGDEE---IILLK EGTDSSQGKPQLISNINACQAIVNAVRTTLGPRGMDKLIV-HGGKATISNDGATILKMLD IVHPAAKTLVEIAKSQDAEVGDGTTSVTLLAGEFLKQCKQFVEEGVHPQIIVKAYRKASN LAIEKIKEISVKVEKTPEHHRELLIKCASTALSSKLVAHQKDFFSPMVVDAVLTLDEYLP LNMIGIKKVTGGGLEDSKLIRGVAFKKTFSYAGFEMQPKKYVNPKIALLNIELELKAEKE NAEIRVDNVQEYQSIVDAEWSILYEKLQKIHESGAKVVLSKLPIGDVATQYFADRDMFCA GRVPDEDLKRTLKACGGAIQTTVQGMKLGTCELFEEIQIGGDRYNMFTGCPKAQTCTLVL RGGADQFMEETERSLHDAIMIVRRAIKNDSIVAGGGAIEMELSKYLREYSRTIPGKEQLL IGAMAKALEIIPRQLCDNAGFDATNILNKLRQKHAGTWYGVDVLSEDIADNLKACVWEPA VVKINALSAASEAACLILSVDETIKSPSAEKQGPGAGRGRGRPMXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMPNIKVFSGTSHPDLAQKVADRLGINLGKVVTKKFSNQETCVEIGESVRGEDVYIIQ TGCGEVNDMLMELLIMINACKIASACRVTAVIPCFPYARQDKKDKSPISAKLVANMLSVA GADHIITMDLHASQIQGFFDIPVDN----------------------------------- SIADRLNVDFALIHKERKKANEVASMVLVGDVKERIAILVDDMADTCGTTCLAAEKLVEA GATKVYAIVTHGILSGPAVSRINNSIFEAVVVTNTIPQEQKMKSASKIQ----------- ------------------------------------------------------------ ------------------------------------------------------------ ----------VAELLGYETDEELEELYQKTAWYFDRKVNKPGASYDIFKHA--------- ---------VLFNNIKRRLTPQAVKLRSDIRVACYKYEGIDAVKAALTKGLDLSTEDMPI KINLIAPPVYVVTTQTIEKQDGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMLDGLKEDLHRQGVTTTAKGHCYACNDP IMGQVITALGRMYHPVHFVCAHCNVELGTGTFFERDGRPFCETDYHNLFSPKCAYCSQPI LDRCVTALDKTWHPEHFFCAECGGQFDETGFHEKNGLPYCRDDYFDKFAPKCGGCATPIM DNYISALNKQWHHECFICQDCHMPFAGGSFFDHEGMPYCETHYHAKRGSLCAGCNKPITG RCITAMYKKFHPEHFVCAFCLKQLNKGTFKEQDQKSYCHACFVKLFMRPLTEEETKLFFE KLSKYIGENIKLLIDRPDGLYCFRYHRDRVFYCSEELLKRAASCARGELLSFGTNFGKFT KTGKFRLHITALDYLAPYAKYKVWLKPSAEQQFLYGHHIMKSGLGRITENTPQYQGIVVY SMSDLPLGFGVAAKSTAECRHADPMTIVTFHQADIGEYLRNEAAL---RNFYVGGNWKMN GNKESINEIIERLNKAVGKTEVVVAPPTCYLEFTRSKLVDVFAQNCYKVEKGAFTGDISP AMIKDIGCDGVILGHSERRHVFGESDQLIGEKVKHALEAGLKVIPCIGEKLDQREAGKTE DVCFEQMKASDWTNVVIAYEPVWAIGTGKVATPDQAQDIHKKIREWVAKEVNPDVASKLR ILYGGSVSGSNCVELAKMPDIDGFLVGGAALKPEFVQIINAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------ENLNTAFDVAEKYLDIPKMLDADDLVNSPKPDEKSVMTYVSAYYHAFSG AQKAETAANRICKVLKVNQENEKLMEDYERLASDLLEWIKRTTPWLENRQTDNTLPGTRS KLEEFRDYRRKQKPPKLEDKMRLESIFNTLQTRLRLSNRPAYLPTEGKMVSDIVNAWKGL ERAEKGFEDWLLAELQRLERLEHLAQKFRHKCDIHEQWSTGKDDMLQNQDFKRCRLSELK AIKKKHEAFESDLAAHQDRVEQIVAIAQELNSLGYHDVLSVNTRCETICTGWDRLGVLTQ ERRAGIEEAEKILDRIDQLHLEFAKRAAPFNNWMDGAKEDLVDMFIVHTTEEIQSLIDAH EQFKSTLGAADSEYNAIIGLVVEVRRIAEQHGIEGANENPYTTLTSRDIELKWSDVRNLV PSRDSTLRQELIRQQNNERLRQQFAQKANVVGPWIERHHDLVMAIGMQKGSLDSQLQKLN GYQNEVMAYKHNIDELERYNQEVQESMIFENRHTPYTMETLRVGWEQLLTSISRAINEVE NQILTRDSKGISEAQLDEFRKSFNHFDKNRSRRLEPKEFKACLVSLGYNIRDDRQGEADF MRIMHIVDPNSSGYVTFDAFLDFMTRETADTDTAEQIVQSFRILAGDRAFITADILRREL PPDQAEYCIQRMAPYSGSDSVAGALDYMSFSTALYGESDLNKLAIDSLDLNGKRILMRVD FNVPMKDGKVTNTQRIAAAVPSIKYALEHGAKSVVVMSHLGRPDGRRQEKYSMKPVHGEL KKLLGRDVTLLNDCVGPEVEAACANPASGSVILLENLRYHVEEEGKGVGEGGEKVKADAA SVAAFRASLTKLGDVYINDAFGTAHRAHSSMVGLQLPQKASGFLLKKELQYFAKALESPD RPFLAILGGAKVKDKIQLIENMLDKVNEMIIGGGMAYTFLKVLKKMKIGTSLYDEEGAKI VEKLMEKAKAKNVQVHLPVDFITANKFSEDADMGSATVDDGIPDGWMGLDCGPKTTALFK EVVSRAKTIVWNGPVGVFEFENFAAGTKGVMDAVVAVTASGTTTIIGGGDTATCAAKWGT EDKVSHVSTGGGASLELLEGKVLPGVADLSDA-------------------MGVFVCELY WKHAPNTCRNFAELAKRGYYNNIKFHRIISDFMIQTGDPTGTGRGGASIYGKAFDDEIHP ELKHTGAGVLSMANSGPNTNGSQFFMTLGPAQWLDGKHAIFGRISQGMKVVKQIGMVECD INDRPIDDIRMV--------RSRSRSKSRKKKPYKYWDKAPTGFEHIQPMQYKAMQASIP FAGSAVSRQARRLYVGNIPFGVTEEHMMDFFNKQMKIAGLAQAEGQPVIAVQINLDKNFA FLEFRSVDETTQAMAFDGINFQGQSLKIRRPRDYQPLPGLTDTPSVGVVSTVVPDSAHKI FIGGLPNYLNEDQVKELLMSFGPLKAFNLVKDSATGLSKGYAFCEYLDIACQGLNGMQLG DKKLIVQRASVGAKNAAQPAVQIQIPGLNLNMSATEVLCLMNMVVPEELEDEEEYEEILD DVRDECGKYGRVKSIEIPRPIKGIEVPGCGKIFVEYHSNEECIRAQQTLAGRKFSNRVVV TSFFDPDKYHRREFFVPLFDRILVQRFEPELKTKGGIMIPEKSMGKVLEATVVAVGPGQL NEAGKNIPLSVSVGDKVLLPEYGGTKVNLEDKEYHLFRDSDLLGKFERLKGQIPDIKTSL DIVKYLIDKKDVIETNFLMSDQLYVKAKIPPTKTVSLWLGANVMLEYTLSDADQLLTKNA ANKSLAQAEEDLSFIRDQTTTLEVNMARVYNHDVKRRQAER-MAQEALESAGLHFDELNK IRVLQPEVATQTSELKEECKEFVDKISEFQKIVGTFIELVDNVAKEVEKEKMKAIGSRNL LKSIAKQREAQQQQLQALIAEKKMQLERLRVQYESLQKEESEQNEFIEQFILQKRERRRD RDREDTRRSRSRDRDRRDLTPEERDARTVFVMQLAPSVRPRDLDEFFSSVGKVRDVRIIT DNKTRRSKGIAYVEFEDVDSVALAMGLSGQKLKDRPLIVQASQAEKNRAGELSGPMRLYV GSLHYNITEDMLKAIFEPFGKIDHINLVMDNETGRSKGFGFVTFHTAEDAKRALEQLNGF ELAGRPMKCGHVTERMIGTSALDSDEMDRAGIDLGATGRLQLMAKLAEGTGMQLPSYAQN ALNMNDTTQAPPIATQCFMLSNMFDPNGSNQNWDQEIKDDVIEECNKHGGVLHIFVDKGS GQGNVYVKCPSIAAAVASVQALHGRWFAGRVITAAYVPLPNYHQLFNEAQNARQLLLSS- EDKDDDISPTPPQPPKKRSRRGAVSAEVYTEEDAASYVKKVVPKDYKTMAALSKSIAKNV LFAHLDDNERSDIFDAMFPVHRHAGEVIINQGDEGDNFYVIDIGEVDIYVNNEWVSTVGD GGSFGELALIYGTPRAATVKAKTDIKLWGIDRDSYRRILMGSTIRKRKMYEEFLSKVSIL ENLDKWERLTVADALEPVQFEDNEVIVKQGEPGEDFFIITEGQAVVHQKRSENEEAVEVG KLGVSDYFGEIALLLDRPRAATVIAKGPLKCVRLVRQRFERVLGSCSDILKRNISQYNSF VSLSVNNYIGIARLNRLIFIADRAYEYVRKTRNTDMYEKICHRIEEHVSQDLPKFNKEFA DSINKEAAQRLERLDIDLKNYRSNSIKESIRRGHDDLGDFYLDMGDLPNALKCYSRARDY CTSAKHLVNMCMNVIKVSAHQGNWQHVLSYANKAESSPEITEHSKDAPSLQTKLRCAAGL AELNLKMYKSAARYFLQANFDNLKYPELVSHRDVAVYGGLCALASFDRQELQKNVLSTSN FKLFLEQEPLVRDTIHQFFQSSYTECLKTMDKLKNTLKLDLYLAPHVNNLYKQIRQRALC QYFSPYLSVNMRTMAKAFNTNIDLLEDELMKLILDGRINARIDSHNKILHAKDVDQRSTT FEKALALGYDYQRRMNTLILRTAVIKHDIQVKAPQRE----------------MSQKNEL LDKAEDIADQVLRNGKHVLPHIARLCLISTFLEDGIRMWMQWDEQRSYINGQWHCGWFLA VLFVIVNLIGQLGGCIMVLSRQKVQIACAILFGIIALQTIAYSILWDLHFLMRNLALAGG VLLLLAESKAEGRSLFAGLPSLGENTSKQYMQLSGRILLVLMFMTLMRFEFSFLDIFQNI FGGFLMGLVAIGYKTKLSALLLVCWLTVINFYFNAFWNVPSYKPMRDFLKYDFFQTFSVI GGLLLVVALGPGGVSVDAQKKKWRQKVTMVPGDGVGPELMNSVREVFSAAGVPVDFEELF LSTNCVGLKGIITTPLETLNMKLRKELDLFANVVKIRSIPGVPTRHGNLDFVIIREQTEG EYSALEHESVQGVVESLKIVTRANSLRIAKFAFDYATKHDRKKVTAVHKANIMKLGDGLF LECCREVAHHYPKIKFDSMIIDNCCMQLVSKPHQFDVMVLPNLYGNIVDNLAAGLVGGAG VVPGESFSKNVAIFEPGARHPFAQAVGRDIANPVAMLLGASNMLKHMHLEFYGQLIEDSV LRVIKAGKVRTPDMGGYSTTTDFNIAVINNLSEEFFKFFDRASRIMERALCEDTNILVDY TGGDKSEELQAGERLKLSRNFFDERWSKHRTVTCIDWSTQFPELLAASYNNNEESPHDPD GVVLVWNLKFKKNSPEYIFHCQSAVMSTCFAKFHPNLVVGGTYSGQIVLWDNRSSKRTPV QRTPLSAAAHTHPVYCVNVVGTQNAHNLISVSTDGKMCSWSLDMLSQPQDSIELQHRQSK VAVTSFSFLAGDVNNFVVGSEEGAVYTACRHGSKAGIGEMFEGHQGPVTGVDCHNVQGQI DFSQLFLTSSFDWTIKLWSIKEQKPLYSFEDNGDYVYDVSWSPIHPALFASVDGQGRLDL WNLNHDTEVPYASTYSAALNRCRWHQSGHQIAAGDDMGRIHIYDIAEHLAHPKNDDWTKF VHTMQEIRNNASDREDE-IQQHLVNATKIVEDQLDAEINKLDHLDDDEMDQIRKRRMAAM KRNKEQKEEYLAQGHGKYFEVPDEKAFFAETKKSKNVVCHFYRDSTYRCKIVDKHLEILA PKHIETKFIKIDAEKCHYLVEKLHIKTLPTICIAKDSKTTDYIVGFGDLGGVDEFPTEML EWRLGVAQVINYSGDLMNPPNDGPTKKTIRDGGADGKCVQLVGFGGIKMVKVVNKPKPEK GEVSVRVKACGMSFMDLMVRQGVIDNPPKTPVTMGFECAGEIDAVGEEVTDFMVGERVIC FREAWAEVVCHVYKMPTNMSFQDGAAFAVNYLTAYMLLIEIGNLKSGQTVFAHSLGGGVG LAIGQLCKTVDNVTLFGTASTKHETIKEN-VEHLFDH-NVDYCQEVKKINPEGLDLVLDC LCGEDTNRGISLLKPMGRYVLYGSSNIVTGETKSFFSFAKSWWQVDKISPIKLYDENKSI SGFTLRQLIIMDKLFQLYNQGKLKPTIDSTWAFEDVAEAMQKMHDRKNIGKIILDPAMMS RKQTPSDFLKQIIGRPVVVKLNSGVDYRGVLACLDGYMNIALEQTEEYVNGQLKNKHGDA FIRGNNVLYISTQKRRIMALPQSALLLKKQLKELQKNPNQTFSAGLKDESDLYVWEIVIM GPPDTFYEGGVFKATLTFPKDYPIRPPKMRFLSEMWHPNVEKNGVVCISILHEPGDDKYG YEKPEERWLPIHTVETILLSVISILADPNPESPANVDAAKEFREAKSEFRKRVSRCVRKS ----------ALTQTQLEFGQYVGECLPKFVQSVKVHTHGELEVRVAPEGIIPVITFLKD HHNGQFLSLADIAGVDYPTRQHRFEIVYNLLSLRYNTRIRVVTYTDEMTPVDSINSIFAG ANWYEREIWDMYGVFFAGHPDLRRILTDYGFEGHPFRKDFPLSGYTEVRYDDETKRLVVE PLELAQEFRKFEYSTPWEMFPHHKKSLNPYCQIDYRSKTWTCNFCFNRNAFPPQYAGMSD QQQPAEIIPQFSTIEYTLTRMTCAPPVFLIVLDTCMDEEDLTAVKESLQMSLSLLPPNAL IGLITYGKMVQVHELGCEGCSKSYVFRGTKDLTAKQIQEMLGIGRGA-QIPFNRFLQPVH KCDMVLTDLLSELQSDPWPVATGKRPLRSTGAALSIAVGLLECTYPNTGARIMVFCGGPC TQGPGMVVDDELKHPIRSHHDIEKDSVKYMKKAMKYYEALAARTANNGHVIDLYSCALDQ TGLHEMKFSCNYTGGHMVLGDSFNTSLFKQTFQRVFSKDARGEFKMAFGASLEVKTSREL KVSGAIGPCVTANNNQCVSDTEIGIGGTCQWKLCGVYPNTTLGVYFEVVSQHNAPIPQGG RGYVQFITQYQHSSGQRRVRVTTLARNWADASVNLPHIAALYDQEASAVLMARMAMFRAE SEEVQDVLRWLDRMLIRLCQKFGDYAKDDPSSFRFSEQFSLYPQFMFHLRRSQFLQVFNN SPDETSYYRHILNREDLTQSLIMIQPILYSYSFTGPPEPVLLDSSSIQPDRILLMDTFFQ IVIYRGETIALWKKEGYHNQPEYENFRQLLHAPADDANEILQTRFPLPRYIDTEYEGSQA RFLLSKVNPSQTHNNMYSDGGAPVLTDDVSLQVFMDHLKKLAVSSSS-----NDQQLKVI ADLEIEMMADMYNRMTSSCHKKCIPPKYKDGELSKGESVCIDRCVAKYLEIHDRIGKKLT SISAQDEETMKKIQAQPQPAVIHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYR KKVTLDGEEVQIDILDDYAAIRDNYFRSGEGFLCVFSITEQESFQASAEFREQILRVKND ENIPFLLVGNKCDLDNKRQVSLEEAQRRATSWNVPYIETSAKTRANVDKAFIDLLQVMRK R----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------FINLNTKSPEYLSLFIDDKLKKGVKGMTEQEIETVLDKTM VLFRFLQEKDVFERYYKHHLAKRLLLNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFKD MTVSNTTMDEFKSHTQQQVNLYGVDLFVRVLTTGFWPTQSAN-KCNIPSTARNAFEAFKS FYLMKHSGRQLTLQPQLGSADLNATFYGSKKDELNSSKGPRKHIIQVSTYQMCILMLFNS RDKYTYDEIQNETDIPEKDLMRAIQSLALGKVTQRILYKEPKGKEIESTDVFSVNDQFTS KLFRVKIQTVAAKGESEPERKETRSKVDEDRKHEIEAAIVRIMKARKLMQHNVLVAEVTE QLKARFLPSPVVIKKRIEGLIEREYLARTPDDRKIYTYVADRINVFPSRMAMKAMKDRLK GAQKGHSLLKKKADALTMRFRQILKKIIETKEKMGEIMKESSFSLAEAKFACGDFNELVL QNVTKAQIKVRTRKDNVAGVLLPVFEPYADGSDCYELTGLSKGGQAIDRLKKNYSKTVEL LVELASLQTSFVTLDEAIKLTNRRVNAIEYVIIPRIERTLSYITSELDEREREEFYRLKK IQKKKAEIRPNNLLDDRDEDLLFPIRVVVTGAAGQIAYSLLYSVGKGDVFGHNQSLVLVL LDIPPMMGTLDGVAMELQDCAMPLVKEVVKTADPNVAFNNADAALLVGAMPRREGMERAD LLKANAKIFEDQGKAMDQHANKNIKVVVVGNPANTNALICAKFAPSIPKENFTCLTRLDQ NRAQAQIALRENVKNIIIWGNHSSTQYPDVNHGTCIREVIKDDAWLNGEFLTTVQKRGAA VIAARKLSSAMSAAKAICDHMRDWWHGTEDGSWVSMGVPSDGYGIPEGLVYSFPVRIDRT YSIVQNLPIDDFSRDKMDKTAAELKDERD----------GVLMVGPNFRVGKKIGCGNFG ELRLGKNLYNNEHVAIKLEPMKSRAPQLHLEYRFYKQLGQAEGVPQVYYFGPCGKYNALV LELLGPSLEDLFDLCDRKFSLKTVLMIAIQLMSRVEYVHSKHLIYRDVKPENFLIGRQSN KKQHIIHIIDFGLAKEYIDPETSKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEAL GHMFMYFLRGSLPWQGLKADNLKERYQKIGDTKRATPIEVLCENFPEELATYLRYVRRLD FFETPDYDYLRKLFTDLMAKKGWECDWEFDWVGKQM------------------------ ------------------MTTIRPFTCDDMFKFNNVNLDPLTENYGLPFYLQYLTHWPEY FQVAESASGEIMGYIMGKSEGHPENWHGHVTALTVAPEFRRLGLAAKLMNIVEEISDKKL CFFVDLFVRVSNKIAVDMYHRLGYTEYRRVIEYYSGDVDEDAFDMRKALSRDVEKLSIIP LKHPVRPIDLEQQLDCALDLMRRLPPQQIEKNLTDLIDLVPQLVEDLLSSVDQPLKIARD KKEGKDYLLCDYNRDGDSYRSPWSNEYDPPLQDGAVPSDRLRKLELESNAAFDQYRELYF DGGVSSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVIEVQEKSSGRSAHYKLTST VMLWLQTNKSGSGTVNLGGSLTKQKEQDTSVTNENTHLVNIGRMVEEMENKIRNELNTIY FDMTKICVNALRSTVSLKQHHMKNELASALAKR--FEDVVDDLDDPLDEVENQEQIELIT SGDLVDPQKRVTTPYMTKYERARILGTRALQIAMCAPVMVELEGETDPLQIAMKELKARK IPIRIRRYLPDGSYEDWGVDELIIT-ATQSIKDAIYAPAGGSSFTIGRGLLAGASVTGLG ALCYYGLGLSNEVGAIDRSVLWPKIVKDRIRDTYMYFGGSIGLTAVSRNPRIMSMMMKNS WLAIGATFAAMIGTGMVARSVPYKEGAKQLAWMLHCGVMGAVIAPITLIGGPLIVRAAWY TAGVVGGLSTLAVCAPSEKFLNMGGPLAIGLGVVFVSSIGGMFFPATSALGAGLYSISMY GGLVLFSGFLLYDTQKIIKRAENHPVYAAVPYDPVNNSIGIYMDTMNIFIRIAMLLAGGG GNKRMEIVYVYTKKRSEFGRQCNFSDRPAELHVDILPDASLADSFIERNPVDTATHCCQE MSEHEVNTERYETDSRGINHTEGGWPKDVNPQEVEQVIRYRKKVEKDEMYVSAIQQLGSQ MEHVIKQNNAIDIYEEYFDDVDADYSEESPSAKTINVFRDQNEIKRTATHISWFPDGPRK LAVAYCNLEFQGSSSDTMDSYIWDIENPNKPEMVLKPSSPLVCVEYNPKDSHVLLGGCYN GQIAYWDTRKGSQPVEMTPVEHSHRDPAYKTIWLQSKTGTECFSASTDGQVLWWDTRKLG EPTEILYLDPTKKQDLTKAQGAMCLEYEPTIPTKFMVGTEQGTVMSCNRKAKTPAEKIVA VYPGHHGPVYSLQRNPFFPKNFLSVGDWTARIWSEDVRESSIQWTKYHMAYLTDGCWSPV RPAVFYTTKMDGTLDIWDFIFKQNDPTLSLQVCDEPLHSIRVQEHGRFIAAGSHSGTTTL LELSDNLCTLQRNEKGLITAMFERETRREKILESRHREMKLKERTKSSYDDLVKYISPIA QPLAPRKLTKKLYKLSKKAVRKGVREVQKFIRKGEKGIVIFAGDTNPIDVVCHMPIVCEE GGLPYCYTPSKEDLGAAYGSRRATCMIMIRPHEDYQELYDELKDQVSGLPQPIMPVDVLE EEGLPQNPDLKLAQWKFLLSTDKYKNDKKIRDDLLEAVKKNNMAPFYEEVCKDLGWKVDS ALLKKMKAENEQALKEIDTKIEDAEANLGETEVRDFMLNKAEYYSKIGDKEATLSQFRKI SEKTTTLGFRLDMVFHQIRLGLFYMDRDLITRNLEKAHTMIEEGGDWDRRNRLKVYRGIF CMSNRDFKTASQLFLDTIATFTSYELMEYKDFVTYTVLCCMIALERPKLREKVVKGSEIL EMLHSLPSVQKYLFSLYNCQYEDFFRNLANVEEVLKYDRYLVLHYRYYVREMRILAYTQL LESYSSLTLDYMAKAFGVTVEFIDKELSRFIAAGRLHCKIDKVGGIVETNRPDSKNYQYQ ATIKQGDLLLNRIQKLSRVINITRGFQNSFDPVKGIPYKDLSIGIPKEIFKNEKRVALHP AATATLKKGFNVNVEESAGVEAKFSNQEYEAAGASVPKDKVFKSDIVLKVRSPDTSEVSL LK-GNNLISFLYPAQNKDLIDQLAKNNMTVFAMDCVPRISRAQVFDALSSMANIAGYKAV IEAANNFGRFFAGQITAAGKVPPAKVLVIGGGVAGLSAVGSAKNLGAIVRCFDTRAAVKE QVESFGAEFLEVNMKESGEGTGGYAKEMSKEFLEAEMALFAKQCKEVDIVITTALIPGKP APKLITKAMIESMKPGSVVVDLASEAGGNIETTKPGELYKYHDVTHIGYTDFPSRLPGQA STLYGNNISKFLLSIGFHINLEDEVTRGAIVLHDGKLLWPAPVPPPPNYFNITLKDSLMY TGGLSGMVGLGMISPNPAFTTMVTTFGLAGIVGYHTVWGVTPALHSPLMSVTNAISGITA VGGLLLMGGGYYPTDIAQALATTAAFISAINIGGGFTVTQRMLDMFKRPTDPPEYNYLYG IPAAAFLGGYGYCAAGTYPDIHQMAYLAASLCCVGALTGLSSQSTSRVGNALGIIGVTSG IAATYGLLKPSPELAVQMAASLGLGGTIGMVAAKRMEVTDLPQMVALFHSLVGIAAVATC FSNFLIEHPHFATDPAAGVIKTSLFLGTFIGGVTFTGSLIAFGKLQGLLKSDPLLLPGRN LLNGGMAAANVAALGAYLATNDTVDLSMLGATAGLSSVMGVTLTAAIGGADMPVVITVLN SYSGWALCAEGFMLNNNLMTIVGAMIGSSGAILSYIMCKAMNRSLPNVILGGYGTSSTGT GKPMEITGTHTEATADGVTDMIVNAKNIIIVPGYGLCVAKAQYPIAELVDLLTKKGKKVR FGIHPVAGRMPGQLNVLLAEAGVPYDQVLEMDEINEDWKETDLVLVIGANDTVNSAAEED PNSIIAGMPVLRVWNSKQVIVMKRTLGVGYAAVDNPIFFKENTNMLLGDAKKTCDALLQK TK----PTVPGCPPGLEYLTQVDQLLVHQQVELFELFTNWETKNKYQIKNSLGQQIYFAA EDSDGCERQCCGPQRGFTMHIVDNTNQEIISVQRPFKCCAGCNCCAGCAMEVSIEGPPGN PIGYIKQQCMEPTYAVMNEILIIEGPAIICAG--CPGDQEFSIYTTKVGAITKQWSGFAK EMFTDADNFGCSFPMDLDVKMKGCLLGAVFLIDFMFFEQKQNGADAELQEFISMEQQKAQ YNQQVHRLADTCWETCLDKPSGKLSSKEETCLTNCVERFIDTSLHITNRFQQIIQNRAMD RSEGLVQRRNVSHGPEDTDSKETRLTLMEEVLLLGLKDREGYTSFWNDCISSGLRGCILI ELGLRGRVELEKCGMRRRGLGLRKILGKSEAPTGDVLLDEALKHVKE-NPPETVQTWIEY LSGETWNPLKLKFQLRNVRERLAKNLVEKGVCTTEKQNFLLFDMTTHPLVDSTMKQKLVK KVQDSVLTKWVNNPQRMDKRMLSLIYLAHASDVLENAFAPLSDDDYELAMKRVRELLELD PEAECMKDGSNELMWAVISAFNK-------SEEDCEVCVKFIKKFQGTLTKIKNAFMKYC KNKKGKDERFCYYVGGLETSATGIVNEMARPVSIGMPAEKVCEKLSMKDSQICDLKYEKQ IDLANTNLKKLKVKDLKKVLSLWDDSCKGCAEKSDFIRRIEELMPEHDPEAYSDDILKGF KLNWMNLRDADSGKVLWQGNEDLSVPGQEHEARVPKKILKCRAVSREINFSSEHELKNFR LEQRVLFKGRCLEEWYFDFGFVIPGSTNTWQSVIEAAPENQMMPANVLTGNVVIETNFYD GEMRVSQSKVCIYYV---------------DEEEYQGEKPLYIHYCLCGNLCCILDCPLE KLPMRRRDNARVIDGAKHAHKLTFEKDGVIHLRREGGLERQYRQKCKKCGLWLFYQHKSN VYFIVDGALKMTSDINTSIVQQTKQPPKVTLTKHTKNMGKFSSVTVSTVDEEEEELEAKE IADSYAANARVIEKQLIRKGLSKRKLMEQAEEESKKRRTKGTLID-----------QLSR SYAEMAFTFASPAEVSVKQVDVPSFSGSFGILPEHVPTLAVLKPGVVTVTEEDGTLKKYF VSSGSVTVNDDSSVQILAEELVTVDMLDMQAIRDGASKAQQEASSETAKAEAEIAMECYE QLQKALECKFLVTELQGRLDETGKYKRMIETGHGLDKKKKIKYNTSELRLIEALQEPHVC DKILEYNLHKERSGSNRFAKGRSETMNTLHGLKAKGVKVELGIPDELWDSPSAEVTDMQK KCYTLVEDYEEVIENWYYNHQENLMDYLCRDRVLAKAKVXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-- -FHFRINGTNADAKSQISRDYPVVDHTYDAVVVGAGGAGLRAAFGLANEGFKTACITKLF PTRSHTVAAQGGINAALGNMEADDWKFHMYDTVKGSDWLGDQDAIHYMTEEAPAAVIELE NYGMPFSRLENGKIYQRAFGGQSIDYGKGGQAHRCCAVADRTGHSLLHTLYGRSLAYDTK YFIEYFAMDLIMEGGECRGVIALCLEDGSLHRFRSKNTILATGGYGRAYFSCTSAHTCTG DGTAMVTRAGLDNEDMEFVQFHPTGIYGAGCLITEGSRGEGGYLINSEGERYMERYAPTA KDLASRDVVSRASTIEIREGRGVGEESDHVYLKLSHLPPEVLQARLPGISETAMIFAGVD VTRDPIPVLPTVHYNMGGTPTNYKGQVIQYKGGDYVVPGLYACGEVACASVHGANRLGAN SLLDLVVFGRACANTIKENHKPGESQPELKSNAGEESVANLDKLRHANGSTPTADLRLKM QKAMQKYAAVFRDGPTLEEGCKVMAKIYQEMDLKLTDRGMIWNTDLVETLELQNLMLNAV QTVDSAENRKESRGAHAREDFSKRIDEYDYSKPIEGQKKKPLEEHWRKHTMIGMDIASGK TKISYRPVIDDTLDDNVCQSVPPAVRSYMTALTQEEIINNTKTVVQGLETLKNEHNQILN SLISSLKTIKKGDTNLVEEKTGILKKSVEMIDLGLGEAQVMMALAQHLQHVEAEKQKLRA QVRRLCQENAWLRDELANTQQKLQQSEQKVATLEEEKKHLEFMNEMKKYDSDDALGFPED DDDPTHHAMAQAASGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHD HPDVATMLNILALVYRDQGKYKEAGNLLQDALCIREKTLGDDHPAVAATLNN-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------TNKCA SQKMGGSRFIADVKGSEMCKEGQGIIGLQAGNKCASQKGMAMGSTRHVSDVKCDEMSKEG QSVIGLQAGSNKGASQSGMSFGGTRHAADIRADDMSADGQAVIGLQAGSNKGASQSGMQF GGQRHAADIRADDLSDGQSIIGLQAGSNKGASQSGMGFGKTRHVADIRADQMGGHNVIGL QAGSNKGASQSGMSMGTQRHVADI------------------------------------ -------------------------NDSDVHIYQTKWEKIHTLSEHTQRVTSVDWAPESN CIVTCGADRNAYVWPTLVILRINRAATCVRWSPNETKFAVASGARLIAICYFEN------ --------------IDWHPNNVLFACGSTDFKVRVFSGFIKEIEAKPQPTSWGKKM---- ------------------------------------------------------------ ---------------------------------------------TVHENTITQISAYEG GKDHVNQFSTSGVDGQLVIWNFK---DGYVGFANLPNQVYRKAVKKGFEFNLMVVGEAGL GKSTLINSLFLTDVYNSEHPGPSQRIKKTLSVEKSQIVLKEGGVTLKLTVVDTPGFGDNV DNSNCWVPLTDFINARFEEFLNAESRVNRKVMPDTRIHCCLYFIQPSGHGLKPLDIEFMK KLHDKANIIPLIAKADTLTVDECREFKKTILNEIAQHNIKIYEFDDDDDNKDLKKLKDRV PFAVIGSNTVMDVGGKKVRGRSYPWGVVEVENLEHNDFIALRNMLIRTHMQDLKDVTNNV HYENFRYNKLASVSXSPLLQMEEEKREHDLKLKKMEAEMEQVFEMKVKEKKQKLKDSETD LQKRAEQMKKSLEQQEKELDEKRKQFERERSQWEETQR---RFFSRTTIFSPEGRLYQVE YAMEAIGHAGTCLGILAKDGVLLAAERRNVNKLLDEVGYSEKIYKLNDDIGCSVAGITSD ANVLTNELRLIAQRYTLYYQEPIPVEQLCSTICDYKQSYTQYGGKRPFGVSILYMGWDKH HGFQLYQSDPSGNYGGWKATCIGNNSSAAVSMLKTDFKEDGMSLDEALNLAIKVLTKTLD TQKLTSEKMEIATLTRVDGKTKIKVLPNQQLDAIIKKLEEEEAKAEAEKKE--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------QEDKIKALDEIASKLIQSEHFA SDDVAQRRDTLLQRRTLLYEKSQTRSRLLQDSLRFQMFERDCDEMKSWINEKLKTASDEG HMDPTNLQAKLQKHQNFQAEIEANTSRMADLNKDGQKLIDDDHYQTKEVKEHLEELDNLW KQLLEQSEKRGKKLGQANDQQQYNRNLEDVELWLSDMEAQIVSEDFGKDLTSAQNLQKKH NVVENDVQQRADRIEAIQAQAAQFQESGHFDADEIVAKKAAVVERYQQLQAPMMARKNKL TDAQKLHQFYRDIEDEEDWIREKEPMAASTNRGRDLIGVQNLIKKHQGLLQDLSTHDPRI EEVTKLGDQMVQDGHFASNDITRKCDDLKDRWANLNDKANKRKEDLEDSLQAQQYFADAN EAESWMKEKEPVVGSQDYGKEEDSSEALLKKHEALMADIDAFKATIETLQLEAATCRQQE TPVVDEHGKEFVYALYDYQEKSPREVSMKKGDMLVLLNSSNKDWWKVEVNDRQGFVPAVY VRKVEGGMTASQNNLAEEFTVATRQKQIQDQYKKLLDLGKQREEKLKESNRAFQLVREAS ELAQWIGEKETIAITEEVSVDLEHVEQQQRKFEDFQKDLKSNEARLMEMNTIAETLEALG QFDAAEKIRAQVQNLNERWTALEQVTAEKATTLMSSHEVQRYHRDVDETLDWIREKDGTL NSDNVGNDLASVQRLQRKHEGIERDLAALGDKVSDLDETANRLMQTHPEQAEGIYHHQTD LNELWNVLTQKADGRKGKLLDSYDLQRFLSDYRDLMNWINSMMALVSSEELAKDVTGAEA LLERHQEHRTEIDARAGTFQAFEMFGNQLLQNNHYASDEVKDKLDNLAQARDALEKAWIA RRMRLDQCLELQLFLRDCEQAETWMATREATISDGVDGA-TVDTMIKKHEDFDRAINAQE EKIDALKSFADQLVAGDHYDKDEIEAKRAEVLDRWSNLKDGLIEHREKLGEAQTLQSFSR DADEIEAWITERMQIAMEESYKDPSNIQSKHQKQQAFEAELAANADRLTQVLGSGQKLID RNQCMGSEDAVKSRIVSLTDQWEYLVTKTREKSAKLKEANRQAVYNAAVKDIEFWLGECE HILENEDYGKDLTSAQNLSRKHQILEADIEAHEDRIKEMNEHADSIVEAGVVDSESIIER KKAINVRYEKITVLSEERRVKLNEANHLYTFFRDIDDEEAWIREKKLLVSSDDFGRDLTS VQNLRKKHKRFEAELVTHEPSHKEVIDAGNQLMEETTMNKDDIESRLKALENSWEELKQL TANRGQKLEESILYQQFCAGIEEEEAWIMEKQHLLSGEDYGDTLAAVQGLIKKHEAFETD SAVHEDRCNDIYKSGDTLIEAGNHNADSIKNRCDNLKEKLTALKNTAATRKARLIDNSAF MQFIWKIDVVESWIADKEVQVHSDDYGRDLSSVQTLLTKQETFDAGLLAFEKEGITTITQ LKDQLVEAKHHQTPTIQKRHDDTITRWKKLLADSEARKKRLLRLQDEYRQVEDLYLTFAK KASAFNSWFENAEEDLTDPVRCNSIEEIKALQYAHDQFKNSLSAAQADFEQLKALDEQIK SFNVGPNPYTWFTMDALIDTWKNLQKIINDRNVDLSREQQRQEENDELRKQFAQSANSFH AWLMDSRAAMMEGSGTLEEQLEAIKAKATEVRAQRGQLKRIEDLGAAMEERLILDNRYTE HSTVGLAQQWDQLDQLGMRMQHNLEQQIQARNQSGVSEDALREFSMMFKHFDKDKSGKLE HKEFKLCLRALGYDLPMVEEGQYDPEFQAILDCVDPNRDGCVSLQEFMAFMISRETENVQ TASDIEQAFRALASEDRPYIKSSELYSNLTKEQTDYCIRNMKPYVDKSGREVPDSYDYKE FCQTLFTN-----------------------------------------------QRSPG WEGWTKVTRRCGSRTDTGVAWGCRYGYEDMGVYKEVCYCDGSDGCN----IDSADAGNPQ LVSEYVNDIYKYMRELEVKELTGRMRAILLDWLVQVHVRFNLLQETLYLTVGIIDRYLQE PVSKTKLQLIGVTAMLIASKYEEMYAPEVGDFEYITDDAYSTAQIRSTELVILKQLDFNL GKPLPLHFLRRNSKAGEVDATKHMLAKYLMELTIIDYELAHVVPSKIAAAALCLSVKVLG WNETLQHYSTYSESDILPVMKKMAILANKRCKSVYEKYSSSKFMRISTIPQLRSQAVKDL -----------------------------LDETIIIFHSLLTGSYAQRFGKDPPASVSIG LRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFQTDGFHAAATNNLCL ATGVRGGVDWMRKLAFRYRRIKELYSSYRNNVGGLLGPQKREQWLQLRSEIEAMTDSWLT LALRSLSIINERSNCVNVLVTTTQLVPALAKVLLYGLGGVFNIENVYSATKIGKESSFER IASRFGRKCTYVVVGDGRDEEAASKQMNWPYWRISSHSDLAALHHALDLGYLIKSLSIGG ERTTGQTIRTQNVMAASAIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILNQLEVEH PAAKILVELAQLQDEEVGDGTTSVVIIAAELLKNADELVNNKIHPTSIISGYRLACKEAV KYIQEHLCIKVDDLGRECIINCAKTSMSSKIIGSESDFFSNMVVDAAMAVKMSDGKGAVR VPIKAVNVLKAHGKSTRESTLVKGYALNCTVASQAMVKKITNAKIACIDFGLMKAKMKLG VQVLVNDPSQLEDIRKRESDITKERVQKILATGANVILSTGGIDDLCLKYFVEAGAMAVR RCKKVDLKRIAKATGGQLVMTLANLEGEEAFEASALGHAEEVVQERICDDELILIKGTKA RTAASIILRGANDFYVDEMERSVHDALCVVKRVLESKSVVPGGGAVEAALSIYLENFAIS LSSREQLAIAEFARSLL----QLSVNAAKDSTDLVAKLRAFHNKSQTEPTHRELKWIGLD LYDGVVRDNKKAGVFEPAISKIKSLKFATEAAITILRIDDMIKLAPEDNKGPSYAQA--- ---DDSVARLLASKNVLNRNIVEGKDLTVEYSIYNVGGSAAFDVKLNDESFPEPDFEKVQ GILQVRWERIAPGTNVTHVVVLRPTKAGYFNFTSAHVNYLAAEEEQLFGYTSAPGYRDII PNKEYDRRFSPHMVDWAAFAVMTLPSLGIPFLLWYSSSKKYDSPKTKKH---SHKDVTER VKAILELIDGLKILFETLINENSSLVVSRQILTEFCNILPKLEDDQAKNISHFILEMIQP RVITFEDQVTAVRQHLSGIYEKEGNWRESADILMGIPLETGQKQYPNEFKLKIYLAIARL SLLYEDSIQAESYVNRASLLQAETKDTVLQITYKACYAMVLDYKRKFIEAAQRYIDISYK KEVVEEEQMFYLQNALICTVLAGAGQPRSRMLATLFKDERCQQLKANSILEKMYLDRIIR KSDLVEFESLLKEHHKAVTGDGSTILDRAVIEHNLLSASKLYNNISFTELGSLLEIQPVK AEKIASQMISEGRMPGYIDQIDSHVYFETRVALPNWDKQIQSLCSQVNTIITQIKTEAPD WFAAHSQ----MKLTEKVVPHFRVAKLFRENQDRINSMNFAASGETLISSSDDDSIVIYD CQNGTPKRNLNSKKYGVDLITYTHATHTAIHSSTKVDDGIRYLSLHDNKYIRYFLGHTKK VVTLNMSPIDDTFLSGSLDKTIRLWDLRSQNCQGLMHLNGRPVAAFDPEGLIFAAGINSE AVKLYDLRSFDKGPFATFRMAQEKDCDWTGLKFSPDGKLIVISTNGQVVRLIDAFQGHPL QTYMGFTNNKGIPIEASFSPDSQFVFCGSTDGRVHCWSTESGNRIAILNAEHSGPVQCVQ FNPKYMHLASACSNMCFWLPQLDE------------------------------------ ------------------------------------------------------------ ---AVNGFALGGGCELAMMCDIIYAGEKAKFGQPEIKLGTIPGAGGTQRLTKAIGKSKTM EMVLTGDMLSAKDA-----------------------------------------NKSYE MTLTEGLNFERRLFHSTFGTADRTEGMKAFIEKRPANFTD >Cerebratulus_lacteus MSERKAVIKNADMSEEMQQDGIDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSG-----RNFQTSAVQRDIDQAAKYIGAGAATV GVAGSGAGIGSVFGNLVIGYARNPGLKQQLFSYAILGFALSEAMGLFCLMMAFLILFAFM SHYKEASKAPAPVIHRIRITLTSRNVKSLEKVCADLIRGAKEKHLKVKGPVRMPTKVLRI TTRKTPCGEGSKTWDRFQLRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADMDQVM AFVEPGKQFAKDSIRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNII V-AAPISKKRKFVADGVFKAELNEFLTRELAEDGYSGVEVRVTPTRTEIIILATKTQNVL GEKGRRIRELTSVVQKRFNFPESTVELYAEKVATRGLCAIAQCESLRYKLIGGLAVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPTNDYVDTAVRHVLLRQ GVLGIKVKIMLPWDPTGKLGPKRPLPDHVSIVEPKEEKVPPQPYSEQKGQKMSKRGRGGS SGGKFRISLALPVGAVINCADNTGAKNLYIIAVHGIKGRLNRLPSAALGDMVVATVKKGK PELRKKVMPAVVVRQRKAIRRKDGTFIYFEDNAGVIVNQKGEMKGSAITGPVAKECADLW PRIASNASSIRKGKVQKVQLGPQVNEGEDVFGVAHIFASFNDTFVHVTDLSGKETIVRVT GGMKVKADRDEASPYAAMLAAQDVAERCKVLGITALHIKLRATGGNKTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRLMGKPSGLRTARKLRNHRRDQRWADKT YKKAHLGTRYKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP RDGCLNFIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKEKKERPRS--- -TLRTRKFMSNRLLCRKQMVVDVLHPGRATVPKTEIREKLGRMYKTTADVIFCFGFRTKF GGGKTTGFALIYDSLDFAKKFEPKFRLVRHGARKQRKEKKNRQKKVRGTAKAKVG-MPHV PLVCSKTFATPRRPFEKERLDQELKLIGEYGLRNKREVWRIKLTLAKIRKAARELLTLDE KDSRRLFEGNALLRRLVRIGVLDEGKMKLDYVLGLRLEDFMERRLQTQVFKLGLAKSIHH ARVLIRQRHIRVRTQVVNIPSYIVRLDSQKHIDFSLKSPFGGGRPGRVRRKNAKKGKGGG GDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMPLAKDLLNPRIEEEKQKCKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQSVVLCV GCSTVLCQPTGGKARLTEGCSFRRKQHMVHMNVLADALKCICNAEKRGKRQVLLRPCSKV IIRFLIVMMKHGYIGEFEVIDDHRAGKIVVNLTGRLNKCGVISPRFDVALRDMEKWTSNL LPSRQFGFLVLTTSGGIMDHEEARRKHLGGKILGFFF-GRMHAPGKGISQSALPYRRSVP VWLKLTPDDVKEQIYKLAKKGLKPSQIGVILRDSNGVAQVRFVTGNKILRILKAKGLAPE LPEDLYNLIKKAVAIRKHLERNRKDRDAKFRLILVESRIHRLARYYKTKKVLAPNWKYDS HTASALVAVAELPEIKLFGRWSSDDVQVGDISLTDYIAVKEKYSKYLPHSAGRYQVKRFR KAQCPIVERLSSSLMMHGRNNGKKLMTVRIVRHAFEIIHLLTGENPLQVLVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREASFRSIRTIAECLADELINAAK GSSNSYAIKKKDELERVAKSNRMSEQMTLRGTLKGHTHWVTQIATNSRYPEFLLSSSRDK SLIVWKLKKEGDYGIAKKKLSGHGHFISDVVISSDGMFALSGSWDKTLRLWDLTTQKTTR QFTGHEHDVLSVAFSPDNRQIVSGSRDKTVKLWNTLGVCKYTIDEGHSDWVSCVRFSPNT SNPIIVSSGWDKIVKVWNLTNCKLKTNHYGHTGNLNCVTVSPDGSLCASGGKDKHAMLWD LNEGKHLYTLDGGDQINALTFSPNRYWLCAATGPSIKIWDLEGKSVVDELRQESLSSG-- PPQCTALAWSTDGQTLFAGYTDHLIRVWQVSVTSQMREYKLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKQVEIDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKLARQFNCSFMETSAKSK INVNEIFYDLVRQINKKNPET--KEEK-SSTHVNVKVTAQDGATVHFKIKKQTPLRKLMH AYCDRQSIKFSSVRFMFDGNHIQQMDTPEDIGLEDDETIEVYLQQTGG---MPLNPKPFL NGLTGKPVMVKLKWGMEYKGYLVSVDGYMNLQLFSTEEYIDGVNMGNLGEVLIRCNNVLY IRGVEEEDEEGEMKDMSDAEGDDQAT--VGAGAMDINTALQEVLKTALIHDGLARGLHEC TKALDTRRAVLCVLANNCDEPGYTKLVEALCAEHTINLIKIDNKKKLGEWAGLCKIDKDG KPRKVVGCSCVVVKDYGKETQAYDVLTEYFKSK-XXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMYTASAKILKPGGEKPDEFEQSISQ AILELEMNSDLKSSLRELYITAAKEIDVQGKKAIIIFVPVPQLKAFQKIQTRLVRELEKK FSGKHVVFIAQRRILPKPTRKTRTKNKQKRPRSRTLTSVHDAFLEDLCYPAECVGKRVRV KLDGTRLIKVHLDKTQQTNIEHKLETFTAVYKKLTGKDVVFEFPDYVLGRGGFRGGFGGR GRGRGRGRGRGKE-DKEWVPVTKLGRLVKDTKIKSLEEIYMFSLPIKEFEIIDLFLENKL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDHDGHVGLGVKCSKEVATAIRGAIILAKLSV VPVRRGYWGNKIGKPHTVPCKVTGKCGSVVVRLIPAPRGTGIVSAPVPKKLLQMAGIEDC YTCARGQTATLGNFAKATYAAIAATYAYLTPDLWKETMFTKPPYQEFTDYLAKMSGGLDV LALKEEDVSKFLASSTHLGANTSDFQMEAYVYKKKSDGVNIINLRRTWEKLLLAARAIAA IEHPADVCVISARPYGQRAVLKFAAATGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDP RTDHQPVQEASYVNIPVIALCNTDSPLKYVDIAIPCNNKGPHSIGLMWWMLAREVLRLRG SISREVPWDVMVDLYFYRDPEEAEKETDVGDWASDPSVNPVPMATEDWGAELTGGASAVP V------MKFNKMVSSSRRKNRKRYFNAPSHVRRKLMSSPLSKELRQKYNVRSMPVRKDD EVQVVRGHFKGQQVGKIVQVYRKKFVIHIERIQRDKANGATVNVGIHPSKVVIVKLKLDK DRKRILDRKSRSRATGKHTEESIASPSSTNVGGTVRQRKATTTTGGGAGMWRFYTEDSPG IKVGPVPVLVMSLLFIASVFMLHIWGKYTRGXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---DKLNKRIGGKGAMRRKKKVIHRTAMTD DKKLTTALKKLSVTTIPQIEEANMFKDDGTVIHFVNPKVQASLTANTFSVIGQSEIKQLT EMLPGILNQLGTEGPTHLQKLAESTEDID-EDDEVPELVENFDVASKGEMTRYSLDPENA TKSAKARGSHLRVHFKNTRETAQAVKKMPLGRAKRYLKNVCDKKEIVPFRRFNGGIGRHA QSKQFGATQGRWPKKSATFLLQLLKNAESNAEYKGLDTDHLMIEHIQVNRAPQMRRRTYR AHGRINPYMSSPCHIEVILAEKEQVVSRPVKKKVSQKKLKRQKMTMRD-------ELTPQ EIRELRSVFETFDGNSDGFLNPIELRNAMKVLGFKVSRDEVKDMSSECTKR--GMCGFSE YLGFVIERQGDRDIQEEILKGFKLMDYDNSSKITLTNLKQATHEAGVNFTEEDLKDADTN GDGVVDKDEFIRIMLQTNLFMGISRDKWHKRRKTGGRREPIRKKRKFELGRPAAGTKLGS KRIHTVRTRGGNKKYRALRLDTGNFSWGSESQTRKTRIIDVVYNASNNELVRTKTLVKNC IVQIDATPFRQWYEAHYATQLGRKKGAKLTEAEEASLNKRSKKTQKKYVERKKTAKVEAP IEEQFATGRLYACISSRPGQCGRCDGYVLEGKELEFYHRKLKAKKGKMSLVIPENFQHIL RVMNTNIDGKRKIMFAMTAIKGVGRRYANVVLKKADIDLKKRAGELSEEEVDRMMTIMSN PRQYKIPDWFLNRQKDVKDGKYSQIMSNGLDSKLREDLERLKKIRAHRGLRHYWGLRVRG QHTKTTGRRGRTVGVSKKKGSGTESDSDESVPELEDMSAASCVQEEPISKAKQSRSEKKA RKALLKNNLKPVLGVSRVTIRKAKNILFIIPKADVFKSPASDTYIIFGEAKIEDVSNQAQ INAAEKFKAGEEVDETGLESKDIELVMQQANVRRGQAVHALKKHSNDIVNAIMMGRVRTK TIKKAGRVIIEKYYPRLTLDFHTNKRICEEIAIIPSKRLRNKIAGFVTHLMKRIQCGSVR GISIKLQEEERERRDNYVPEVSAIEEVDPDTKEMLKMLDFANIPGLQVTQPIAQTXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMRELRIRKL CLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVRSFGIRRNEKIAVHCTVRGPKAE EILERGLKVREYELRKGNFSATGNFGYGIQEHIDLGIKYDPSIGIYGMDFFVVLGRPGFN VAHKRRKRGKVGFQHRITKEEAMKWFQQKYDGVILPGKXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQTEKAFQKQPTVFLNKKKALLPRYYK SVGLGFKTPREAIEGTYIDKKCPFTGNVNIRGRILTGTVLKMKMQRTIVIRRDYLHYVRK YNRFEKRHKNMSVHLSPCFRDVKLGDIVTVGECRPLSKTVKFNVVKVTKGAGSKKGFEKF MVNVPKQRRTFCKGKKCKRHTLHKVTQYKAGKASLFAQGKRRYDRKQSGYGGQTKPVFHK KAKTTKKIVLRMECTDCKYRKQLPIKRCKHFELGGDKKRKGQMIQFMGRVIRSQRKGAGS VFKSHTKNRKGAAKLRAVDYAERHGYIKGVVKDIIHDPGRGAPLARVVFRDPYKYKLRTE TFLASEGLYTGQFIYCGKKASLQTGNILPVGSMPEGTIICCLEEKTGDRGRLARTSGNYA TVISHNPDTKRSRVKLPSGFKKVIPSANRAVVGIIAGGGRIEKPMLKAGRAYHKYKVKRN SWPKVRGVAMNPVEHPHGGGNHQHIGHASTVSRDKSAGRKVGLIAARRTGRLRGTKQITQ KXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRRPARCYRYCKNKPYPKSRFCRGVPDA KIRIFDLGRKKAGVDEFPLCIHLVSDEYEQLSSEALEAGRICCNKYMVKSCGKEGFHIRI RVHPFHVLRINKMLSCAGADRLQTGMRGAFGKPQGTVARVNIGQPIMSVRARENHKANVI EALRRAKFKFPGRQKIILSRKWGFTKWEKPLYETMRADGRLIPDGVSAQYKPHHGPLKHW LDRQKVIRILGRTGSQGQCTQVRVEFLDDTNRSIIRNVKGPVREGDILTLLESEREARRL RMTKGTSSFGKRHNKTHTLCRRCGRSSYHIQKKTCAQCGYPAAKTRHYNWSVKGKRRKTT GTGRMRYLKIVHRRFRNGFREGTEPKPRKAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-GAYKYMQELYRKKQSDVMR FLLRVRCWHYRQLSTIHRVSRPTRPDKARRLGYRAKQGFCIYRIRVRRGGRKRPVAKGAV YGKPVHQGVNQLKFNRSHQSVAEERVGRKCGSLRVMNSYWVAQDSTYKYFEIIMVDPFHK AVRRCPDLQWICTSKSKHREMRGLTSAGRKSRGLGKGHSYNATKGGSRKAAWRRNNFQQM HRKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGKSSKMLQHINFRMRCTL QDGRVFVGTFKAFDKHMNLILGDCDEFRRVRPKSSKQREEKRVLGLVLLRGENLVSMTVE GPPASEEGMPRVPAAGAGPGPGVGRAVGRGMG-GGGLQGPVRGVGGPSSSMMAPG--MAR GGPPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSIGV PIKVLHEAEGHVVTCETTAGEVYRGKLVEAEDNMNCQMSNITVTLRNGQVEQLENVYIRG SKIRFLILPDMLKNAPMFRKVAAGRGKSAILRAAARGRGRGRGGGDRDRMQNDAGDFVDM YIPRKCSASNKIIHAKDHASIQINFAEVDETTGRMTGSNKTYAICGAIRRMGESDDCLLR LAKKDNMVAKMPRGPKKHLKRLNAPKHWMLDKLSGVFAPKPSCGPHKMRECLPLMIFLRN RLKYALTYDECTKIVMQRHIKVDGKVRTDKNYPAGYMDVITIEKTSENFRLIYDVKGRFA VHRITAEEAKYKLCKVKKLGIAQKGVPYIVTHDGRTIRYPDPLIRVNDSVQVXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXERKPYSPFQNASTAEYAVAR VDDLMNWARKSSLWPLTFGLACCAVEMMHFAAPRYDMDRFGVVFRASPRQADCIIVAGTL TNKMAPALRKVYDQMPDPRRVISMGSCANGGGYYHYSYAVVRGCDRIVPVDIYVPGCPPS AEALLYGVLQLQKKIKRMKT-------TDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYA NNSNYKNDTMIRKEAYVHKSVMEELKRIIEDAEIMREDDSLWPPPDRVGRQELEIVIGDE HISFTTSKIGSLVDVHQSKDTEGLRTFYYLVQDLKCLVFSLIGLHFKIKPIMAPTKKSKK AIENINSRLALVMKSGKCVLGYKQTLKALRQGKAKLVIIANNTPPLRKSEIEYYAMLAKT GVHHYNGNNIDLGTACGKYFRVTVLSITDPGDSDIIRSMP--XXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKIELCA FSGYKVYPGHGKKLVRVDGKVYQFINAKSQASFLMKRNPRKISWTVLYRRKHKKGQQEEQ QKKRTRRTTKYQRAITGATLSDIMAKRNQKPEVRKAQREQAIRAAKEKSRSKKSKAPRVG GKRMKLNISYPATGCQKLIEVVDDLKLRNFYEKRISAEVAGECLGDEWKGYVFRISGGND KQGFPMKQGVLTATRVRLLLGAGHSCYRPRRSGERKRKSVRGCIVDAQLSVLSLVIVKKG EQDIPGLTDTTIPRRLGPKRATKIRKLFNLSKEDDVRQYVVRRPLEAQTKAPKIQRLVTP VVLQRKRRRMALKKKHTAKKREAAAEYAKLLAQRMKEKKEKKMERRRSASASKKVKAKEL RTRKKEELLKQLEDLKQELAALRVTKVTGGAASKLSKIRVVRKSIARVYTVIHQKQKENL RKYYKPKDLRQKKTRAMRRALTPFEKSLKSSKQIRRERAFPMRKYAVK------------ --------------------------------------SYNGSIFHRVIEGFMIRGGDFV TGNGFGG----------------------------------------------------- ------------------------------------------------KKKKTTLKFVID CTLPVEDGIMDAGSYERYLHERIKIQGKTNNLKSKVSINSEVPFSKRYLKYLTKKYLKKN NLRDWLRVVANSKESYELRYFQINNEEEEEEGDEXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXMSFLLQKLSDKKAVDEVIKNTEDVILVLRFGRENDSTCLRLDDILS KAEEELSRMAKIFIVDVDSVPVYTRYFDISLIPATIFFFNAQHMKVDWGTPDHTKFIGSF RNKQDFIDVVEVLYRGAMRGKLMVPSPLD-------XXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXTAPFDARFPNQNQTRNCWQNFVDYHRCQKIMDYE PCEYFKRIYTSICPKQWHETWTE-----------XXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPKEKVHINIVVV GHVDSGKSTTTGHLIYKCGGIDKRAIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITI DIALWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVASGTGEFEAGISKNGQT REHALLCYTLGVKQMIVGCNKMDSTEPPYSEARFAEISKEVSGCLKKLGYNPKAVAFVPI SGWHGDNMLKMPWFKGWNIASGKTLFEALDSILPPKRPTEKPLRLPLQDVYKIGGIGTVP VGRVETGTLSPGTIVNFAPPNITTEVKSVEMHHETLTKA--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPRQ INEIKDFLLTARRKDAKSVKIKKNVKFKVRCKRFLYTLVIQDREKAEKLKQSLPPGLAVK ELKMSKLSRETLIEAIATILQKKRKFTESVELQISLKNYDPQKDKRFTGTVKLKNIPRPK LKICVLGDQQHCDEAKANTIPCMDVEALKKLNKNKKLVKKLAKKYDGFLASDSLIKQIPR ILGPGLNKAGKFPSVLSHSEAMAQKVEEQKATIKFQMKKVLCLSTAVGHVKMTQDELVAN CVLAINFLVSLLKKNWQNVKALYVKSTMGPAQRIYXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXX-----IQNFNDPFACSGTVHIRIQQRNGRKFITTVQGLVVDKYEKLL IKKWKKDFNCNGSLGTCSLGLTTYILQGNHQEAVKNFLLKHELKDQIKVHSWXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX MESLYSIPFTVLECPNLKLKKPTWVKMPSAMVVFALILGSYFLVTGGIIYDVIVEPPSIG STTDERGNSRPVAFMPYRVNGQYIMEGLASSFLFTIGGLGFVILDQTNKPTTPKLNRILL LSVGFVSILVSFFMCRVFMRMKLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXLVRFLTKLSHETVTIELKNGTQVHGTITGVDVSM NTHLKNIKMTQKNRDPVGLDSLSIRGNNIRYFILPESLPLDTLLIDDTPKARAKKASMQK PKSEMSPEELAQREQEEFSAGPLSILTMSVKNNTQVLINCRNNKKLLGRVKAFDRHCNMV LENVKEMWTEFPRAGKGKKKAKAVNKDRYISKMFLRGDSVILVLKNPLPIIIDARGHLLG RLAALVAKTILNGQRVVIVRCEEINISGSFYRNKLKYLDFIKKRCNVNPKRGPFHFRAPS KIFWRTVRGMLPHKLSRGKEALDRLKVFEGIPMPYDKEKRMVVPSALKVLRLHPRRKFCR LGRISHEIGWKYQNVVNTLEGKRRARSADFYRKKKVETVWRNKATKVAAHQKVIESYGYD GDATKGAKVFKQRCSQCHTVDNNGKHKTGPNLHGLIGRKTGQAPGFSYTDANKKKGITWG KDTLWVYLEKPAKYIPGTKMVFAGIKKKQERADLIAYLEEAT-IFVERTLAIIKPDAVSE EIEDIILRSGFTVLQKRRVNLTPEQASDFYAEHFGKLFFPSLVAYMSSGPIIGLVLSREK AISYWRELIGPTNTLKARQTHPDCLRAIYGTDDQRNALHGSDSHHSAEREIRFFFPDSVV EPIPTGQAARDYLSKSVNPTLLKGLTELCKQKPSEPVTWLADWLLENNPNKPKIQMFEAK LENGSMWRKIVEAVKDIIENAIFDCSSNGIKLQGMDSSHICLVHLELHKDGFNSYRCDRN IALGVKVENLLKLLRCAGPNDAITFRAENGGDTLMLIFESPSPNKVSKYEMKLIDLDQEH LGIPDQDYSCTVRMPSGEFSRICRDLSQIGDTVIVTCAKDGITFSCSGDLGTGQVTLQQT VNMDKEKDQVVIEQKEGVNLNFSLRFLTMFSKAAPLSSRVKLNLAPAIPLVCEYEIEEI- ----------------KTVASYHTSRRKPVGQVVAVIGAVVDVQFEDELPPILSALEVEN RTPRLILEVAQHLGESTVRTIAMDGTEGLVRGQKCQDTGHPIRIPVGPETLGRIINVIGE PIDERGPVPTDKRASIHAEAPEFVEMSVQQEILATGIKVVDMLAPYAKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIEGGVINLKDDSSKVSLVYG QMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFPQAGSEVSAL--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------MLMSKKNRIMIFEHLFKEGVLVAKKDHSLPKHPEVEVPNLHVI KALQSLKSQGYVKEQFAWRHYYWSLTNEGIQYLRDFLHLPPEIVPSTLKRQDMGADRQAY RRGGGGDKKGDVGAGATXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX MTNPKGYRRGTRYMFSRQFKKHGVTHLSKYLKVYKRGDIVDIKGDGAIQKGMPHKSYHGR TGRIYNVTQHAVGVIVNKRVRGRILAKRINLRIEHIKHSNCRLDFISRVKKNEALKKEAK EQPNCKRMPEGPRKAHFVRTKLNKPQVIEPIPYEFVAXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXKKLTKEEELLLQDFSRNVTTKSSALFYGNAFIVSAIPIWLFWR IHQMDPSIIFGVMTLISTYLVAFAYKNVKFVLKHKIALKREEAVSREVMKKVADDKRMSK KEKDERILWKKNEVADYEATTFSIFYNNALYLVLMVVASFYILRSVNPSVNYILSVVVSS GLLALFSTSTKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXMAEYLASIFGTEKDKVNCSFYFKIGACRHGERCSRLHNKPTFSQTILIPN LYINPQNSALIQLSDVEMQQYYDEFFEEVFVELEDKYGEIEEMNVCDNLGDHLVGNVYVK FRYEEDAEKAVQGLNNRWFNGRPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKP ISRELRRELYGRYRRSRSRSPPTRRSHSRSRRERRRRSRSRSRERXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDVENELLDYEE-EEQEAKDVKGSYVSIHSS GFRDFLLKPELLRSIVDCGFEHPSEVQHECIPQAILSMDVLTQAKSGMGKTAVFVLATLQ QLEPVENQVSVLVLCHTRELAFQISKEYERFSKYMNGVKIAVFFGGITIKKDEDTIKKNC PHIVVGTPGRILALAKALNLKHVKHFILDECDKMLEQLDMRGDVQEIFRMTPHEKQVMMF SATLSKEIRPVCKKFMQDPMEVYVDDDSKLTLHGLQQHYVKLKDTEKNRKMFDLLDVLEF NPVIIFVKSLQRCIAL-------------------------------------------- ----------------------------------------------------XXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---- -------------------------------------------VGTFPFNSFLSGFISCV GSFVLAVCLRVQVNPSNKNDFLTISVERAFADFVFAHVILHLVIMNFIGXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXMGKFMKSGKVVLVLNGRFAGRKAVIVKNYDEGTSEKPYGHALVA GVDRYPRKVTKRVGKKKIKQRSKIKAFVKVFNFNHLMPTRYSVVALEKSLVNKDSFRDPA LKRKARREVKTKLEERYKTGKNKWFFQKLRFERTLIILKPDAVQRGLVSNIIGRFEQKGF KLVGMKMLKASRELVAKHYERFKKLKYYEGLCDYMSSEPVVPMVWEGDVVKTSRMLLGET DPTKSLPGTIRGDYSVHIGRNVIHGSDSAGTATEEIALWFKPEELCDWEPSQNKWLYEKK AAKPVAVPTKAKDKALKAKKNVLRGVKDKRKRKIRTSVHFRRPKTLKLARAPKYPRRSTP KRPRLDQFKIVKFPLTTESAMKKIEDNNTLVFVVDKRANKPQVKLAVKKLYDIDVAKVNT LIRPDGEKKAYVRLAPDYDALDVANKIGIIMPSKQRMRVANEKHTKNVTNRGNVPKTLKP SEEKYPVGPWLIALFIFVVCGSALFEIIQHIRLXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX---IFCKIARGEIPSTKIHEDDQCFVIRDIAPQAPVHLLVIPR KCVESVAADQQLLGHMMRVVAKVAEAQEGFRTVMNTGPNGGQDVMHLHIHVLGKREMNWP PXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXRLYSKAVFTGYKRGLRNQHESTALLKIEGVITKKDTNYYLGKKCCYVYKA KNKTACPGHDKSSHIRIIWGKVTRPHGNSGVVRAKFRRNLPAKAMGRRIRVMMYXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXMAARPLITVYSDKNEPTGTNVTLPAVFKAPIRPDIVNFVHFEMLKNTRQPYAV SVQAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRK INVNQKRYAMCSAIAATGIPSLVMSKGHRIEQTPEVPLVVSDKVEEIKKTKEAVVFLKKF KAWADIEKVYNSKRFRAGKGKMRNRRRIQRRGPLVIYNQDNGISRAFRNIPGITLINVSR LNLLKIAPGGHVGRFCIWTESAFKRLDALYGTWRKPSKEKNDYNLP-------------- ------------------------------------------------------------ -----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSHRKFSAPRHGSLGFLPKKRSKRHRGKV KAFPKDNRNKPCHLTAFLGYKAGMTHIVREADRPGSKINKKEIVETVTIVEAPPMVVVGA VGYVETPKGLRTFKTVFAEHLGEECRRRFYKNWYRSKKKAFSKYSKKWADESGKKEIEKD FRMMKKYCKVIRVIAHTQMKLMKKRQKKAHIMEIQVNGGSIAQKVDYVREHMEKKIPINT VFDKDEMIDVIGVTKGKGYKGVTSRWHTKKLPRKTHKGLRKVACIGAWHPSRVGFSVARG GQKGYHHRTEINKKIYRIGQGIHTKDGKVIKNNAXTDYDITDKSITPMGGFPHYGKVNND YV---------------------------------------------------------- ------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGK DYSVHRLILGTHTSDEQNHLLIASVQLPNDNAQFDASHYDSEKGEFGGFGSVSGKIEIEI KINHEGEVNRARYMPQNPCVIATKTPSSDVLVFDYTQHPSKPEPTGECNPNLRLKGHQKE GYGLSWNPNLNGCLLSASDDHTICLWDISQASREKQNLDAKTIFTGHTAVVEDVSWHLLH ESLFGSVADDQKLMIWDTRSTHTTKPSHTVDAHTAEVNC--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---MPLPSRARVYPDVNTHRPREYWDYESHVVEWGQQDDYQIVRKLGRGKYSEVFEAINI TNNEKCVIKILKP----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSKAHPPELKKYM DRKLNLKINGKRKVQGVLRGFDPFMNVVLDDAFEEKKVDDNRKIGRVVIRGNSVILLESL ERIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXMAPRYEMACGLNKGHKVTTRKPRPSRRKGAQTKHVRFIRDVVR DVVGYAPYERRCIELLRVSRDKRALKFVKKRLGTHIRGKRKREEMQQVIQAQRK-XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------------- ------------------------------------------------------------ ---------------------------------------------------------KEY ADTLGIPFFETDPEDTENVERAFVALAAAMKSRMEAAGVE-------------------E ESLGEDVLRMGTDEIVSRTRLLDNEIKIMKSEVMRISHELQA------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------XXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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MTDRKAVIKNADMSEDMQQDAVDCATQALEKYNIEKDIAAFIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSGPITQLRGFQTSAVQRDIDQAAKYIGAGAATV GAAGAGAGIGSVFGSLVIAYARNPSLKQQLFSYAAMGFALTEAMGLFCIIMAFLILFAFM SHYKETGKAPEATIHRIRITLTSRNVKSLEKVCADLIKGAKEKNLKVKGPVRMPTKILRI TTRKTPCGEGSKTWDRYQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADMDQVM QFVEPAKTFAKDSIRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNII VMAAQISKKKKFVADGVFKAELNEFLTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVL GEKGRRIRELTSVVQKRFNFPEGTVELYAEKVATRGLCAIAQCESLRYKLIGGLAVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPTNDYVDTAVRHVLLRQ GVLGIKVKIMLPWDPSGKIGPRRPLPDHVSIVEPKEEQIPKEPISEQKGGKMSKRGRGGS SGGKFRISLALPVGAVINCADNTGAKNLYIISVHGIKGRLNRLPAAGSGDMVMATVKKGK PELRKKVMPAVVVRQRKTIRRKTGLFIYFEDNAGVIVNNKGEMKGSAITGPVSKECADLW PRIASNAGSIRKGKTVKVQLGPQAVEGENVLGVAHIFASFNDTFVHVTDLSGKETIVRVT GGMKVKADRDEASPYAAMLAAQDVAERCKTLGITALHIKLRATGGNRTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRLMGKPRGLRTARKMRNHRRDQRWHDKD YKKAHLGTRWKANPFSGASHAKGIVLEKIGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP NDGCLNYIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKEKKERPRSESA ATLRTRKFLTNRLLCRKQMIVDVIHPGRATVPKTEVREKLARMYKTTADVVFCFGFRTQF GGGKTTGFALVYDSLDFAKKFEPKYRLQRHGSSKQRKERKNRQKKVRGTAKAKIGAMPRV PLVCSKTYTTPRRPFEKERLDQELKLIGEYGLRNKREVWRIRYTLAKIRKAARELLTLDE KDPRRLFEGNALLRRLVRVGVLDESKMKLDYVLGLRLEDFLERRLQTQVFKLGLAKSIHH ARVLIRQRHIRVRKQVVNIPSYVVRLDSQKHIDFSLKSPYGGGRPGRVKRKNAKKGGRGD AGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMPLAKDLLHPSLDEERRKCKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRRKQHMVRMNVLADALRSICNAEKRGKRQVLIRPCSKV IIKFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVALSDLEKWTNNL LPSRQFGFLVMTTSGGIMDHEEARRKHLGGKILGFFFMGRMHTPGKGISQSALPYRRSVP TWLKLSPDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKAKGLAPD IPKDLYHLIKKAVAIRKHLERNRKDKDSKFRLILIESRIHRLARYYKSKKVLPPNWKYES ATASALVAVAEIPEIKLFGKWSSDDVQVSDISLTDYIAVKEKYAKYVPHSAGRFQVKRFR KSQCPIVERLTSSLMMHGRNNGKKMLAMRIVKHAFEIIYLLTGENPLQVLVNAVINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGSREAAFRNIKTIAECLADELINAAK GSSNSFAIKKKDELERVAKSNRMTEQMTLRGTLQGHGGWVTQIATTPQYPDMILSASRDK TLIMWELTRDTNYGVQKKRLRGHGHFVSDVVMSSDGQFALSGSWDGTLRLWDLNTGLTTR RFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIEDCHSEWVSCVRFSPNT GNPIIVSCGWDKLVKVWNLTNCKIKTNHIGHNGFLNCVTVSPDGSLCASGGKDGQAMLWD LNEGKHLYTLDGGDKINALTFSPNRYWLCAATGPSIKIWDLEGKIVVDELRQEVISTXCR APECVSLAWSADGQTLFAGYTDXLIRVWQVSMAAKXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXMSEEKKDSTEHINLKVTGQDGSVVHFKIKKNTPLRKLMS AYCDRTGVKMGVMRFRFDGQPINEQDTPLQLEMEDGDSIDVFQQQTGGXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXMSDAEGDDVPVSVSVDGAMDTNTALQEVLKNALIHDGLARGLHEC AKALDKRQAHLCILANNCDEPMYVKLVEALCAEHGINLIKVDDNKKLGEWAGLCKIDKEG KARKVVGCSCVVVKDYGKETQALDVLNEYFKSKKXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFSASAKIIKPQGEKPDEFESSISQ ALLDLEMNSDLKAQLRELYISGAKEIDVAGKKAIIIFVPVPQLRAYQKIQVRLVRELEKK FSGKHVVFIAQRRILPKPTRKTRTKNKQKRPRSRTLTTVHDNILEDLCHPAEIVGKRIRI KLDGSRLIKVHLDKSQQTNIEHKMDTFTAVYKKLTGKDVIFEFPDYVMXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSGNLDV LALKEEDVTKFLACSTHLGSTNVDFQMEQYCYKRKPDGTYIINLRKTWEKLLLAARAIAA IENPADVCIISARPYGQRAVLKFASATGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDP RTDHQPVTEASYVNIPVIALANTDSPLRYVDIAIPCNNKSAHSIGLMWWLLAREVLRLRG TISREVPWDVMVDLYFYRDPEEAEKEPEVADWATDGIVAPVPITTEDWSAQTTDDWSAPA ATNEWGGMKFNKLVSGSRRKNRCRHFNAPSHMRRKIMSSPLSKDLRQKYNVRSIPIRRDD EVQIVRGHYKGQQVGKIVQVYRKKFVVHIERIQREKANGASVHVGIHPSKVVIVKLKMDK DRKRILERKARSRQVGKHTEESVASPSSTNVGGTVRQRKTTSGAGSGAGMWRFYTEDSPG IKVGPVPVLVMSLLFIASVFMLHIWGKYTRGKKGEKKKSTINEVVTREYTVNVHKRIHGV GFKRRAPRAIKEIRKFAEKMMGTPDVRIDTRLNKHMWSKGVKNVPFRVRVRLARKRNEDE DSPHKLYTLVTYVPVDTFKGTETNNVDASSKSEFLVNGKYRLVRKIGSGSFGDIYLGINI SNGEEVAVKLESHKARHPQLLYESKLYKILQGGVGIPHIRWYGEKDYNVLVLDLLGPSLE DLFNFCSRRFTMKTVLMLADQMIGRIEFVHNKNFIHRDIKPDNFLMGIGRHCNKVFLIDY GLAKKFRDNRTRQHIVYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRGS LPWQGLKAAT-------------------------------------------------- ------------------------------MNKEKLKQRIGGKGSAKKKKKVVHRTATTD GKKLQSTLKKLAVNNIPGIEEVNMIKEDGQVIHFNNPKVQASLTANTFALTGHAEQKQIT EMLP-ILNHLGAESLSNLRKLATATDDIDDDEDDVPXLIENFDEASKGEMARYSLDPENA TKSAKARGSHLRVHFKNTRETAQNIKKMHLHRAFKYLKNVVNKAECVPFRRYSGGVGRCA QAKQWSTTQGRWPKKSAEFLLQLLKNAESNAEYKGLETDHLVIEHIQVNRAPKMRRRTYR AHGRINPYMSSPCHIEVILAEREQAVAKAVKKKVSQKKLQRQKMMMRE-------ELSEE QKQEIRESFELFDTDKDRFIDYHELKVAMRSLGFDIKKAEVLKILKDYDREGSGKISFDD FNEVMTDRMLDRDPQEEIMKAFRLFDDDDSGKISLRNLRRVARELGENLGEEELRAFDKD GDGEINASEFVAIM------MGISRDKWHKRRKTGGRQEPIRKKRKYELGRPAANTKIGA RRIHTVRTRGGNKKYRALRLDTGNFAWGSEAQARKTRIIDVVYNASNNELVRTKTLVKNC IVQVDSTPFRQWYEAHYATALGRKKGAKLTEAEESVLNVRSKKTQKKYDERKKTAKVDSI LEDQFGTGRVLACISSRPGQCGRADGYILEGKELEFYQRKIKAKKGKXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRVRTK TVKKAARVIIEKYYTRLGNDFHTNKRICEEIAIIPSKPLRNKIAGFVTHLMKRIQRGPVR GISIKLQEEERERRDNYVPEISAIEEVDPDTKEMLKMLDFGNIQGLQVTQPIQSVXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMRELRIRKL CLNICVGESGDRLTRAAKVLEQLTGQQPVFSKARYTVRSFGIRRNEKIAVHCTVRGPKAE EILERGLKVREYELRRNNFSHTGNFGFGIQEHIDLGIKYDPSIGIYGMDFYVVLGRPGFN VSQKENAXGVVGVQHRVQKEESMKWFQQKYDGVILPGKMGIKFLEFVKPFCAVIPEIAKP ERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGIS PIVTSSLIMQLLAGAKIIEVGDTPKDRALFNGSQKLFGTVLTICQAIVYVMTGMYGDPSD IGAGVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVN TGRGTEFEGAVIALFHLLATRADKVRGLREAFYRQNLPNLMNLMATVLVFAIVIYFQGFR VDLPIKSARYRGQYSSCPIKLF-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------QTERAFQKQPTVFLNRKRNLLLRYSK SVGLGFKTPREAIDGTYIDKKCPFTSNVSIRGRILTGVVLKMKMQRTIVIRRDYLHYIRK YNRFEKRHKNMSVHLSPAFRDVTQGDIVTVGECRPLSKTVRYNVLKVAKGAGGKKGFQKF MVNVPKSRRTFCKAQKCRKHTLHKVTQYKKGRDSLAAQGKRRYDRKQSGYGGQTKPIFHK KAKTTKKVVLKMECTECKYKKQLAIKRCKHFELGGDKKKKGQMIQFMGRVIRSQRKGPGS VFTAHTKNRKGAAKLRAVDFAERHGYIKGVVKDIIHDPGRGAPLAKVVFRDPYRFKLKTE TFVASEGMYTGQFLYAGKKXTLQIGNILPVGSMPEGTVICCLEEKTGDRGRIARGSGNFA TIISHNPDTKRTRVRYPSGSKKVLPSANRAMVGIVAGGGRIDKPMLKAGRAYHKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGHASTVRRDCSAGKKVGLIAARRTGRLRGTKQITG KAKRTKKVGITGKYGTRYGASLRKLIKKMEVTQHSKYTCSFCGKENMRRKVVGIWSCKSC RKTVAGGAYVYSTTQAATVRSGVRRLREMKEXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXRVTKVLGRTGSQGQCTQVRVEFLDDSNRSIIRNVKGPVREGDILTLLESEREARRL RMTKGTSSFGKRHNKTHTICRRCGRSSYHIQKKRCASCAYPNPHKRHFNWSVKAKRRRTT GTGRQRHLKIVFRKFRNGFREGQVAKPRSKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGAYKYMQEIYRKKQSDVLR FLLRVRCWQYRQLSAVHRATRPSRPDKARRLGYRAKQGFVIYRVRVRRGGRKRPVPKGAT YGKPTNQGVNQLKFQRSLQNVAEERAGRRCGGLRVLNSYWVAEDSTYKFFEIIMVDPFHK AIRRDAKVNWICNSVHKHRELRGLTSAGKRSRGLGKGHKFNSTIGGSRRAAWKRNNTTSL RRKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGKSSKMLQHINFRMRCIL QDGRIFIGTFKAFDKHMNLILGDCDEFRKVRPKNAKSREEKRVLGLVLLRGENLVSMTVE GPPPAEEGIARVPIPGAGPGPGMGRAAGRGVP-GGGLQGPVRGVGGPSQQMMQPQGGMGR GGPP----TFKLVLVGDGGVGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGAVRF NVWDTAGQEKFGGLRDGYYIQGQCAIIMFDVTARVTYKNVPNWHRDLVRVCESIPIVLCG NKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPA LAPPEVQMDPNMAKQYEAELEIAQQVALPEDADD-XXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXLSFAENFALSGAAAVISKTAAAPIERVKLLVQNQDEMIKQGRLAEPYKGVIDCTM KTYRSEGIIPFWRGNLANCIRYFPTQALNFAFKDQIKALFKSSKNDSYAVKFSKNIASGG AAGALSLFFVYSLDYCRTRLANDAKSAGKREFNGIIDVYKKTIKSDGVQGLYRGFVISCV GIIVYRGCYFGFYDTLKPLLLGPDAGILASFALGYVVTISAGLVSYPIDTIRRRMMMTSG QAVKYKGSIDCTVQILKNEGFMSLMKGAGANILRGVAGAGVLAGFDKFKDLYIRW--MSD CCDLDRQIEQLRRCEIIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLK ELFRVGGDVPDTNYLFMGDFVDRGFYSVKTFLLLLALKVRYPDRITLIGGNHESRQITQV YGFYDECLRKYGSITVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRGIDRK QEVPHDGPMCDLLWSDPEDTNGWGVGPRGAGYLFGSDVVAQFNAANDIDLICRAHQLVME GYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQRDFTIFEAAPQESRGKPQADYFL VRLPPEVNRILYIRNLPYKITAEEMYDIFGKYGAIRQIRVGTTPETKGTAFVVYEDIFDA KNACDHLSGFNVCNRYLVVLYYQSNKAFKKLDQEKKREELDKMKQKYGLSTPDNKMSIGV PIKVLHEAEGHIVTCETTTGEVYRGKLVEAEDNMNCQMSNITVTYRDGRVSQLENVFIKG SKIRFMILPDMLKNAPMFKRVGAGRGKSAILRAAARGRGRA--------MQNEAGEYVDM YIPRKCSASNRIIQAKDHASIQLNIAEVDESTGRMTGAHKTYAICGAIRRMGESDDCLIR LAKRDNVIAKMARGPKKHLKRLHAPKHWMLDKLGGVFAPRPSTGPHKLRECLPLMVFLRN RLKYALTYDECKKIMAQRLIKVDGRIRTDKTYPAGFMDVITIEKTAENFRLIYDIKGRFS VHRITSEEAKYKLCKVKKLSVGPKGVPFVVTSDGRTIRYPDPLVRVNDSVQVXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMTEYKLVVVGAGGVGKSA LTIQLIQNHFVEEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGF LCVFAVNNNKSFEDINQYREQIKRVKDADEVPMVLVGNKVYLQVRQVDQKQGKSLADFYN IPYIETSXKTRQGVDDAFYTLLEK----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKVELCV YSGLKIYPGHGKRLVKIDGKGYQFLNAKCERSHMMKRNPREINWTVLYRRKHRKGQTEEV AKKRTRRTTKFQRAITGASLSDILAKRNQKPEVRKAQREQAIRAAKEKQKAKDKAQPRVG GKRMKLNVSYPATGCQKLIEVDDEHKLRSFYEKRMASEVSAEALGDEWKGYIVRITGGND KQGFPMKQGILTNDRVRLLLSKGHSCYRPRRTGERKRKSVRGCIVDANLSVLNLMIVKKG EQDIPGLTDKTIPRRLGPKRASRIRKLFNLSKEDDVRQYVVRRPLPPQTKAPKIQRLVTP MTLQRKRHRVALKRKRAAKKRDDAAEYAKLLVQRLKEAKERKMERRRSASQSKKVKAKEL RGKKKEELLKQLEDLKQELLTLRVAKVTGGAASKLSKIRIVRKSIARVLTVINQTQKENL RKFYKPKDLRPKKTRAIRRALSKNEAALKTKKQERKERLYPMRKFAVKXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKKKKVVLKFTID CTHPVEDGIMECANFEXFLQERVKVNGKAGNLKSKLIVTADIPFSKRYLKYLTKKYLKKN NLRDWLRVVANAKDSYELRYFQINNEEEEEDEGDXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTRIITLDELKQHNNAKSCWFTVHDKVYDVT KFLEEHPGGEEVLLEQAGKFGTESFEDVGHSTDAREMMEQFYVGDLAEEDKSTWVSWLLP LGIAIAAALVYRF-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---PLSLDMI RDRVLLVLKLYDKVDPEKLTLESHFMNDLGLDSLDTVEVIMAMEDEFGFEIPDSDAERLL TPKDIVQYIADKEDIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGAEKTHINIVVI GHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEASEMGKGSFKYAWVLDKLKAERERGITI DIALWKFETEKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQT REHALLAYTLGVKQMIIGVNKMDSTEPKYSKARFEEISKEVTSYIKKIGYNPAGVPFVPI SGWHGDNMLNMPWFKGWTTGSGQTLISALDNITPPTRPTDKALRLPLQDVYKIGGIGTVP VGRVETGVIKPGMVVTFAPPMVTTEVKSVEMHHQALE-KQSLRHVGFNVKNVSVKDIRRG NVXGDSKADPPKAAENFTAQ---------------------------------------- ------------------------------------------------------------ ---------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXMTRGRTELGDVTMHNIKQLKRLNQVVFPVTYNDKFYKDVL EVGELAKLAYFNDIVVGAVCCREDKTDGLRRLYIMTLGCLAPYRRYGIGTVMLQHVLKIC QEDANYDNIYLHVQINNESAIKFYEKFGFEIVEKKENYYKRIEPADAFVLQKTLRKMPKQ IMDIKDFLLTARRKDAKSVKIKKNVKFKVRCSRYLYTLVIQDREKAEKLKQSLPPGLAVK ELKMSKIPRDTLIDAVQTIMKKKRNFTESVELQISLKNYDPQKDKRFSGTVKLRHIPRPK LKVCVLGDAQHIDEAKANNISCMDVDDLKKLNKNKKLVKKLAKKYNVFLASDSLIKQIPR ILGPGLNRAGKFPTLLTHSESMVSKVEDVKATIKFQMKKVLCLAVAVGHVNMAQDDLVSN VNMSINFLVSLLKKNWQNVRALYVKSTMGPAIRIYMADADKLSIDSIIARLLEVRGSRPG KNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEQKEVP-------------------- ---MFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEIVGTNVSTT FITCPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPF ICTMPMRLDEGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDEL PAEFKLYLPVQNKM--TDIRNLNDPFADAEGIHIRIQQRNGRKTLTTVQGINSEYDLKKI VKHCKKVFACNGTVVEHGEYGEVIQLQGDQRCRVADMLISSSMEDQVKVHGFXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXSSRLTATLVRQLPRAVAKQNALGAGFVSCRNLSASAEVSSILEERILGAPKANLEET GRVLSIGDGIARVYGLKNIQADEMVEFSSGLKGMALNLEPDNVGIVVFGNDKLIKEGDIV KRTGAIVDVPVGEALLGRVVDALGNPIDGKGPIDTDLRQRVGTKAPGIIPRISVRDPMQT GIKAVDSLVPIGRGQRELIIGDRQTGKTAIALDAIINQKRFNDAQDEKKKLYCVYVAIGQ KRSTVAQIVKRLTDTDAMKYTIVVSATASDAAPLQYLAPYAGCAMGRVLQRQRQHALIIY DDLSKQAVAYRQMSLLLR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MEALYNIPFAFFECPNLKIKKPTWIKQPSPMTTFSIILVSYFLVTGGIIYDVIVEPPSIG STTDERGNSKPVAFMPYRVNGQYIMEGLASSFMYILGGLGFIILDQTNKPLMPKLNRILL LSVGFVSVLISFFTLRIFMRMKLPMPKVKRSRKPPPEGWELIEPTLDELDQKMREAETDP HEGKRKVESLWPIFRIHHQRSRYIFDLFYKRKAISRELYEYCLKENIANKNLIAKWKKQG YENVCCLRCIQTRDTNFGTNCICRVPKSKLEEGKIVECVHCGCRGCSGEYAQVIKMLGNG RLEAMCFDGTKRLCHIRGKLRKKVWINTTDIILIGLRDYQDAKADVILKYTPDEARNLKT YGELPESTKINEDQDDNITFEDIDEILVRFLMKLSHETVTIELKNGTQVHGTITGVDVCM NTHLKAVKMTVKNKDPVQLDTLSIRGNNIRYYILPDSLPLDTLLIDDTPKARAKK--MQK PKSEMTPEELSQREQEEFNTGPLSVLTQSVKNNTQVLINCRNNKKLLGRVKAFDRHCNMV LENVKEMWSEVPKTGKGKKKSKPVNKDRYISKMFLRGDSVILVLRNPLPIIIDARGHLLG RLAAIVAKTILQGQRVVVVRCEEMNISGNFYRNKLKYLDFLKKRCNVNPRRGPFHLRAPS KIFLRTVRGMVPHKLARGKDALEKLKVFEGIPPPYDKQKRLVVPSALKVLRLQPRRKFCR LGRLSHEVGWKYQNVVATLEAKRKIKSKAHYERSKTITQLKSQAVKIAQHQQVIESYG-A GDATKGKKIFVTRCAQCHTVEKGGKHKTGPNLNGLFGRKTGQAEGFSYTAANQSKGITWG RDTLFIYLENPKKYIPGTKMIFAGLKKKNDRADLIAYLEESTKXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFEAR LTQASLLKKVLEAIKDLLTDVTWDCNSTGMSLQAMDSSHVSLVSLMLRCDGFDTYRCDRN MTMGINLGSMSKILKCAANDDALTLKVGDNADVVTFMFESPNQEKVSDYEVKLMDLDTEH LGIPETDYSCVIKMPSAEFQRVCRDLSQVGESVVICCTKEGVKFSTTGDLGTGNIKLAQT ANVDKEEEAVIIEMQEAVTLTFALRYLNFFTKATPLAAQVSLSMSADVPLXVEYKFADMG YVRYYLAPKLEDNEDAKSVAAYHTTNRTATGRVVAVIGAVVDVQFDDELPPILNALEVQD HSPRLILEVAQHLGENTVRTIAMDGTEGLVRGQVCLDTGNAIKIPVGPETLGRIINVIGE PIDERGPVNSKHHLAIHQEAPEFIDMSVEQEILVTGIKVVDLLAPYSKGGKIGLFGGAGV GKTVLIMELINNIAKAHGGYSVFAGVGERTREGNDLYHDMIATGVIDLKGNNSKVSLVYG QMNEPPGARARVCLTGLTVAEFFRDHEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVX YQPTLATDMGTM------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------MLMPKKNRVAIYEHLFKEGVMVAKKDFYAPKHPELDVPNLQVI KAMTSLKSRGYVNEQFAWRHFYWYLTNEGIQYLRDFLHLPPEIVPATLKRQAMGADRAEY RRGAGADKKADVGAGATXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------EQVGDKEYDMSFDAMTD RAAVHTFFGEITKGMSIVIGQVFKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAICPAQAISIEAETRADGSRRTTRYDIDMTKCIFCGFCQEACPVDAIVEGPNFEY ATETHEELLYNKEKLLDNGDKWEQAIAANLQADHLYRMASPAKVAKPEGKNNHDNDKEQQ EAIEQIDEVQNEIDRLNENASEEILKVEQKYNKLRQPYFQNRSELIAKIPNFWVTAFVNH PQVSALLNEEDEEALQFLTKVEVQEFEDIKSGYRINFNFDSNPYFENTCISKEFHLNSSK STPIKWKAGKDLTKKSKKRNHEEQESFFSWFTDHGDAGADELGEVIKDDIWPNPLQYYPA SEIEEEGADEEGIDEDDKKLTKEEELLLQDFSRNVTTKSWALFYGNAFIVSAIPVWLFWR IHQMDPIIIFVVMTLVSTYLVAFAYKNVKFLLKHKIAQKREEGVSRDVMKQVAEDKKMSK KEKDERVLWKKNEVADYEATTFSIFYNNALFLVLVILASFYVLRSFSPTFNYVASMGTAG GLLALFSTSTKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXMAEYLASIFGTEKDKVNCSFYFKIGACRHGERCSRLHNKPTFSQTVLLQN LYLNPQNTAQVHVSDVKVQQHYDDFFEEIFVELEQKYGEIEEMNVCDNLGDHLVGNVYVK FRYEEDAEKAVNDLNNRWFNSRPVHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKP ISRELRRELYGRKRRRRSRTPPARRSRSRSRRSPGRRGRSRER--XXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---EELLDYEE-DEHEAKDVKGTYVSIHSS GFRDFLLKPEMLRAIVDCGFEHPSEVQHECIPQAILSMDVLCQAKSGMGKTAVFVLATLQ QLEPVDGQVSVLVLCHTRELAFQISREYERFSKYMSNTKIAVFFGGVSIKKDEEVLKKNC PHIVVGTPGRILGLVKNLNLKHIKHFILDECDKMLEQLDMRRDVQDIFRMTPHEKQVMMF SATLSKDIRPVCKKFMQDPMEVYVDDDSKLTLHGLQQHYVKLKDNEKNRKLFELLDVLEF NQVIIFVRTVQRCMALAQLLVEQXFPAIAIHGAMGR------------------------ ----------------------------------------------------PPTYGDLG KSARDIFGKGYNYGFFKLECKTKTANGVQFTSSGSQNQDTNKVGANLETKYKCSDYGLTF TEKWNTDNILATEITIEDQIAQGLKLTFDTSFAPQTGKKSGRIKSGYKREYVNLNCDVDF DFAGPTIHGAAVLGYNGWLAGYQMSFDKSKLAKSNFAVGYSTDDFTLHTNVNDGSEFGGS IYQRVSSDFETGVSLSWTAGTNATRFGLGAKYTPDKDTTIRAKINNSSQIGLSYQQKVRD GVTLTLSSLLEGKSFNQGGHKIGLGLDLE-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMTES LFSVVTKFYDEYSNSTSKKLKIVDAYLTYILLTGVVQFVYCALVGTFPFNSFLSGFISCV GSFVLGVCLRLQVNPQNKSEFLGISPERAFADFIFAHLILHLVVINFIGXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXVIDHYENPRNVGSLDKEDRTVGTGLVGAPACGDVMKLQIKVDDDG KIVDAKFKTFGCGSAIASSSLATEWIKGKTISEARKIKNTDIAKELSLPPVKLHCSMLAE DAIQAALKDYKIKNQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXMGKFMKSGKVVLVLGGRYAGRKAVIVKNYDEGTQDKQYGHALVA GIDRYPRTVTKRMGKKKIKQRSKVKPFVKVYNFNHLMPTRYSIVNLDKAVVNKDAFRDPA LRRKARREVKGKLEERYKTGKNKWFFQKLRFERTFIMVKPDGVHRGLVGETIKRFEQRGY KLVAIKFMQASEDHLKEHYADLAGRPFFPSLIKYMASGPVVPMVWEGNSVKVGRMILGET KPIESLPGTLRGDFCIDVGRNIVHGSDSVDSAKKEISHWFKAEELVPWQICNDPWIHEAD APKPVKTGSKSKDKALRARKSVLRGVHGKRQRKVRTSVHFYRPKTLRLSRQPKYPRKSTP RRNRFDQFKIVKFPLTTESAMKKIEDNNTLVFIVDKLANKHQIKLAVKQLYDIDVSKVNT LNRPDGEKKAYVRLAPDYDALDVANKIGIIMASKQRMRVANDKHSKNITTRGNVPKSLKP TEEKYPVGPWLLGLFVFVVCGSAIFQIIQSIRFXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXMAARPLISVYSEKGESSDSNVTLPAVFRAPIRPDIVSFVHSEMRKNTRQPYAV SEKAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRR INVNQKRYAMCSAIAATGIPALVMSKGHRIEEIPEVPMVVSDKIEEYKKTKEAVGLLRRL KAWSDIEKVYSSKRFRAGKGKMRNRRRIMRRGPLIIYNQDNGICRSFRNIPGTTLINVNR LNLLKIAPGGHVGRFCIWTESAFKKLDAIYGTWRKASTEKNNYNLPMPKMTNNDLARLLK SEEXQKALRAPKKDITRKVLXRNPLKNKRAMXELNPFAAVQKKTAK-------------- -----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------QMRAT INQKLIETGERDRLKELLRTRLIECGWRDQLKAYCKEVVKQKGLEHITVDDLVAEITPRG RALVPDQVKKELLQRIRNFLAVQSNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXMSHTILMVQPGRKPEGRTYSDYESVNECLEGVCKIFEEYLKRMNPNSPSITYDISQ LFDFIDQLADLSCLVYQKSTGTYVPHNKDWIKEKIYILLRKQAGKMAEQTEEKKTEEVKR -VHTYPLIRHSDMNEEMRTETMELCVTACEKFSNNNESAAKLIKDTMDKKFGASWHAVVG EGYGFELTHEVKNLLYMFFGGNMAIVVWKCSMSHRKFSAPRHGSLGFLPKKRSKRIRGKV KAFPKDDPSKPIHLTSFLGYKAGITHIVREVDRPGSKLNKKETVESVTIIETPPMVVVGV IGYIETPHGLRTFKTVFAQHLSEECRRRFYKNWYRSKKKAFTKYSKKWQDEQGKKEIEKD FNKMKKYCKVIRVICHTQMKLMKKRQKKAHVMEIQVNGGSISQKVDWAREHLEKQVPITD IFDADEMIDIIGVTKGKGFKGVTSRWHTKKLPRKTHKGLRKVACIGAWHPSRVSFSVARA GQKGYHHRTEINKKIYRIGKGHPHQGRKGRQNNASTEYDLTEKTITPLGXFPHYGE-SHD FIMIYGCCV--------------------------------------------------- ------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXIFDPSLKKKKKKKTPFDLDGAMDEISLDDNLTKKKKKKKKVF DMDELGDALPKTDGSLPKKKKKSNTDRDYTYDELLNRVFDIMREKNPDMVAGEKKRFIMK PPQVMKIGTKKTSFSNFAEICKMLHRQPKHLLAFLLAELGTSGSVDGNNQLIIKGRFQQK QIESVLRRYIKEYVTCHTCRSPETILQKDTRLFFLQCESCGSRCSVASIKSGFQPLL-KR AAIRAK--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQVPESILKRRKQNAAKNRVKRREMFKRAE KYVKEYRVKERDDIRLHRQAKKTNSFYVPAEPKMAFIIRHRGINGIHPRPRKILQLFRLR QINNGVFVKLNKATLNMLRIADPYITWGYPNLKSVRELVYKRGYGKIEGKRLPLTDNALI EKKLGQYGIICIEDLIHEIFTVGPHFKEASNFLWPFKLNTPNGGWRIKNEHFVDGGDFGN REDKINALLKKMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSKAHPPELKKYM DKRLSLKLNGSRQVTGVLRGFDPFMNLVVDEAVEETKTGQKNNIGMVVVRGNSIVLLESL DRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXMVLKYDMAVGLSKGHKVTKLKPRPSRRKGQLNKHVKFIRDIVR EISGFAPYEKRAMELLRISKDKRALKFCKKRLGAHIRGKRKREEMQMTLQNMRKAXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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TPYSGGQFRMKLVLSSNFPSEPPKAYFLTKIFHPNVAKNGEICVNTLKKDWKPQLGIKQV LLTIKCLLIVPNPESALNEEAGKLLLEQYDDYSTRAKLYTEIHARPXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXMAELLLDSEIRFWVFLPIVIITFLIGILRHYV TILLSSEKKVELSQITDSQVLIRSRMLRENGRFIPRQAFLMRKHYFNDKDDGFFMKNPMT DPSMMTDMLKGNLTNVLPMIVIGGWINWAFSGFLTTKVPFPLTYRFKPMLQRGVELSSLD ASWVSSASWYFLNVFGLRSMYNLILGQDNAADQTKVMQDQMSGAAMAMPPDPTKAFKAEW EALEICDHQWALEGIEEEV-MFLWDWFAGILNFLGLYKKSGKLVFLGLDSAGKTTLLHML KDDRMAQHVPTLHPTSEELSMGGMRFTTFDLGGHQQARRVWKDYFPAVDGIVFLVDACDR ERFQEAKAELDSLLSDEQVAGAPVLVLGNKIDVAGAASEEEIRHLFGLHGQTTGKGTVSR SELRPMELFMCSVLKRQGYGEGFRWLAQYINXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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SYIEGYVASQADSAVFAQLSGPKATFVHALRWYSHIKSF--DTSSLPGVAKSVDQYGPAG TADDDDDDDVDLFGSEAERIKQERLAAYAAKKAPGLIAKSNIILDVKPWDDETDMDAMEK SVRAIEMDGLLWGASKLVPLAYGIKKLQICCVVEDDKVGTDDLEEKIIEIEDFVQSMDIA AFNKIKVQEIREVTRIERIGAHSHIRGLGLDDALEARNVSQGMVGQMPARRAAGIILEMI KEGKIAGRAILIAGHPGTGKTAIAMGMAQALGQDTPFTSIAGSEIFSLEMSKTEALTQAF RKSIGVRIKEETEIIEGEVVEIQIDRPAAGTGAKVGKLTLKTTDMETVYDLGQKMIESLT KEKVQAGDIITIDKATGKITKLGRSFTRARDYDAMGAQTRFVQCPEGELQKRKEVVHTVS LHEIDVINSRTQGFLALFSGDTGEIKAEVREQISAKVAEWREEGKAEIVPGVLFIDEVHM LDIESFSFLNRALESDMAPILIMATNRGITRIRARSTRVTR-IPIDLLDRLLII------ ------------------------------------------------------------ -------------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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TTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADMDQVM QFVEPAKTFAKDSIRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNII VMAAQISKKKKFVADGVFKAELNEFLTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVL GEKGRRIRELTSVVQKRFNFPEGTVELYAEKVATRGLCAIAQCESLRYKLIGGLAVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPTNDYVDTAVRHVLLRQ GVLGIKVKIMLPWDPSGKIGPRRPLPDHVSIVEPKEEQIPKEPISEQKGGK-SKRGRGGS SGGKFRISLALPVGAVINCADNTGAKNLYIISVHGIKGRLNRLPAAGSGDMVMATVKKGK PELRKKVMPAVVVRQRKTIRRKTGLFIYFEDNAGVIVNNKGEMKGSAITGPVSKECADLW PRIASNASSIRKGKAQKVQLGPQAVEGENVFGVAHIFASFNDTFVHVTDLSGKETIVRVT GGMKVKADRDEASPYAAMLAAQDVAERCKVLGITALHIKLRATGGNRTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRLMGKPRGLRTARKMRNHRRDQRWHDKD YKKAHLGTRWKANPFSGASHAKGIVLEKIGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP NDGCLNYIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKEKKERPRSDSA ATLRTRKFLTNRLLCRKQMIVDVLHPGRATVPKTEIRDKLARMYKTTADVVFCFGFRTQF GGGKTTGFALIYDSLDFAKKFEPKYRLQRHGSSKQRKERKNRQKKVRGTAKAKIGAMPRV PLVCSKTYTTPRRPFEKERLDQELKLIGEYGLRNKREIWRIRYTLAKIRKAARELLTLDE KDPRRLFEGNALLRRLVRVGVLDEGKMKLDYVLGLRLEDFLERRLQTQVFKLGLAKSIHH ARVLIRQRHIRVRKQVVNIPSYVVRLDSQKHIDFSLKSPYGGGRPGRVKRKNAKKGGRGD AGMGNVFQKMFTSLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVIDSNDRERCNEAREELLRMLAEDELRD ALLLVFANKQDLPNAMNAAEITDKLHLHTLRNRKWYIQATCATSGDGLYEGLDWLSQTLK NQ-MPLAKDLLHPSLDEEKRRCKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCSS-----------------------MVRMNVLADALRSICNAEKRGKRQVLIRPCSKV IIKFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVALSDLEKWTNNL LPSRQFGFLVMTTSGGIMDHEEARRKHLGGKILGFFFMGRMHTPGKGISQSALPYRRSVP TWLKLAPEDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKAKGLAPD IPEDLYHLIKKAVAIRKHMERNRKDTDSKFRLILIESRIHRLARYYKSKKVLQPNWKYES ATASALVAVAEIPEIKLFGKWSSDDVQVSDISLTDYIAVKEKYAKYVPHSAGRFQVKRFR KSQCPIVERLTSSLMMHGRNNGKKMLAMRIVKHAFEIIYLLTGENPLQVLVNAVINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGSREAAFRNIKTIAECLADELINAAK GSSNSFAIKKKDELERVAKSNRMTEQMTLRGTLKGHGGWVTQIATTPQYPDMILSASRDK SLIMWKLTRDTNYGVPQRALKGHGHFVSDVVMSSDGQFALSGSWDSTLRLWDLSTGQTTR RFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIEDCHSEWASCVRFSPNT QNPIIVSCGWDKLVKVWNLTNCKLKTNHIGHTGYLNCVTVSPDGSLCASGGKDGQAMLWD LNEGKHLYTLEGGDKINALTFSPNRYWLCAATGPSIKIWDLEGKIVVDELRQEVISTGAE PPECISLAWSADGQTLFAGYTDNLIRVWQVSMAAR------------------------- --------------------VDGNQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERV-------------------- ---------------------MSEEKKDSTEHINLKVTGQDGSVVHFKIKKNTPLRKLMS AYCDRTGVKMGVMRFRFDGQPINEQDTPLCLEMEDGDSIDVFQQQTGGXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXMSDAEGDDVPVSVSVDGAMDINTALQEVLKTSLIHDGLARGLHEC AKALDKRQAHLCILANNCDEPMYVKLVEALCAEHGINLLKVDDNKKLGEWAGLCKIDKEG KARKVVGCSCVVVKDYGKETQALDVLNEYFKSKK-------------------------- -------------ENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSI DSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDENTRRELAKMKQEPVKPEEGRS MAEKINAFAYLECSAKTKEGVREVFETATKAALQVKKKKKNKXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFSASAKIIKPQGEKPDEFESSISQ ALLELEMNSDLKAQLRELYISGAKEIDVGGKKAIIIFVPVPQLRAYQKIQVRLVRELEKK FSGKHVVFIAQRRILPKPTRKTRTKSKQKRPRSRTLTTVHDNILEDLCHPAEIVGKRIRI KLDGSRLIKVHLDKSQQTNIEHKMDTFTAVYKKLTGKDVIFEFPEYVMGRGGFRGGFGGR GRGRGRGRGRGKEGDKDWVPVTKLGRLVKDLKIKTLEEIYLFSLPIKEFEIIDFFLGSAL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDHNGHVGLGVKCSKEVATAIRGAIILAKLSV VPVRRGYWGNKLGKPHTVPCKVTGKCGSVLVRLIPAPRGTGIVSAPVPKKLLNMAGIEDC YTCACGQTATLGNFAKATYAAIANTYGYLTPDLWKETVFTKSPYQEHTDYLAK------- ------------------------------------------------------------ ----------------------------------------------------RLLVVTDP RTDHQPVTEASYVNIPVIALANTDSPLRYVDIAIPCNNKSPHSIGLMWWLLAREVLRLRG TISREVPWDVMVDLYFYRDPEEAEKEPEVTDWATETIVAAVPITTDDWSAQTTDDWSVAA Q------MKFNKLVSGSRRKNRCRHFNAPSHMRRKIMSSPLSKDLRQKYNVRSIPIRKDD EVQIVRGHYKGQQVGKVVQVYRKKFVVHVERIQREKANGASVHVGIHPSKVVVVKLKMDK DRKRILERKARSRQVGKHTEESVASPSSTNVGSTVRQRKTTSGAGSGAGMWRFYTEDSPG IKVGPVPVLVMSLLFIASVFMLHIWGKYTRGKKGEKKKSTINEVVTREYTVNIHKRIHGI GFKRRAPRAIKEVRKFAEKMMGTPDVRIDTRLNKHMWSKGVKNVPFRVRVRLARKRNEDE DSPHKLYTLVTYVPVTTFKGTQTINVDSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNPEKLKQRIGGKGTQRRKKKVVHRTATTD GKKLQSTLKKLSVNNIPGIEEVNMIKEDGCVIHFNNPKVQASLTANTFAITGHAENKQIT EMLPGILNQLGAESLANLQKLATGTDDIDDDEDGVPDLVENFDEASKGEMARYSLDPENA TKSAKAKGSHLRVHFKNTRETAQNIKKMHLHRAVKYLKNVVTKSECVPYRRYSGGVGRCA QAKQWSTTQGRWPKKSAEFLLQLLKNAESNAEYKGLETDHLVIEHIQVNRAPKMRRRTYR AHGRINPYMSSPCHIEVILAEREQAVAKAIKKKVSQKKLKRQKMMMREXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXMGISRDKWHKRRKTGGRQEPIRKKRKYELGRPAANTKIGA RRIHTVRTRGGNKKYRALRLDTGNFAWGSEAQTRKTRIIDVVYNASNNELVRTKTLVKNC IVQIDSTPFRQYYEAHYATPLGRKKGAKLTENEESVLNVRSKKTQKKYDERKKTAKVDGL LEDQFGTGRVLACIASRPGQCGRCDGYILEGKELEFYQRKIKAKKGKMSLVIPEKFQHIL RVLNTNIDGRIKIAYALTAIKGIGRRYSHVVIKKADVDLTKRAGELTDEEVDKVTTIMQN PRQYKIPDWFLNRQKDVKDGKYSQVISNALDNKLREDLERLKKIRAHRGLRHYWGLRVRG QHTKTTGRRGRTVGVSKKKNSGTDSDSEDSMPELEDMAAAAGLQEELVSKAKQSRSEKKA RKAMSKLGLKHIAGVSRVTIRKSKNMLFVISRPDVYKSPASDTYIVFGEAKIEDLSQQAQ MAAAKQFKAEEEVDEGGVEAKDIELVMSQANVSRGKAVKALKNNQNDIVNAIM------- ------------------------------------------------------------ -------------------------EVDPDTKEMLKSLDFGNIQGLQVTQPIQSVXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMRELHIRKL CLNICVGESGDRLTRAAKVLEQLTGQQPVFSKARYTVRSFGIRRNEKIAVHCTVRGPKAE EILERGLKVREYELRRNNFSQTGNFGFGIQEHIDLGIKYDPSIGIYGMDFYIVLGRPGFN VSQKKRKRGVVGPAHKVQKEESMKWFQQKYDGVILPGK---------------------- -----------WTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGIS PIVTSSLIMQLLAGAKIIEVGDTPKDRALFNGSQKLFGTVLTICQAIVYVMTGMYGDPAD IGAGVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVN TGRGTEFEGAVIALFHLLATRSDKVRGLREAFYRQNLPNLMNLMATILVFAIVIYFQ--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------QTERAFQKQPNIFLNKKRNALLRYHK SVGLGFKTPREAIDGNYIDKKCPFTSDVSIRGRILTGVVLKMKMQRTIVIRRDYLHYIRK YNRFEKRHKNMSVHLSPAFRDVTPGDIVTVGECRPLSKTVRYNVLKVAKGAGGKKGFQKF MVNVPKSRRTFCKAQKCRKHTLHKVTQYKKGRDSLAAQGKRRYDRKQSGYGGQTKPIFHK KAKTTKKVVLKMECSECKYKKQLAIKRCKHFELGGDKKKKGQMIQFMGRVIRSQRKGPGS VFTANTKNRKGAAKLRPVDFAERHGYIKGVVKDIIHDPGRGAPLAKVVFRDPYRFKLKTE TFVASEGMYTGQFLYAGKKATLQVGNILPVGSMPEGTIICCLEEKTGDRGRIARGSGNFA TIISHNPDTKRTRVRYPSGSKKVLPSANRAMVGIVAGGGRIDKPMLKAGRAYHKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGHASTVRRDCSAGKKVGLIAARRTGRLRGTKQVTG KAKRTKKVGITGKYGTRYGASLRKLIKKMEVTQHSKYTCSFCGKENMRRKVVGIWCCKSC KKTVAGGAYVYSTTQAATVRSGVRRLREMKEMGRRPARCYRYCKNKPYPKSRFCRGVPDS KIRIFDLGRKKAKVDDFPLCIHLVSDEYEQLSSEALEAGRICANKYLVKICGKDGFHLRV RVHPFHICRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQPIMSVRGRESDRDHII EALRRAKFKFPGRQKIHVSRKWGFTKWDKTVYEGMRQDGRLVPDGVTVQYRPNHGPLKRW KDAQRVTKVLGRTGSQGQCTQVRVEFLDDSNRSIIRNVKGPVREGDILTLLESEREARRL RMTKGTSSFGKRHNKTHTICRRCGRSAYHIQKKRCASCAYPNPHKRHFNWSVKAKRRRTT GTGRQRHLKVVFRKFRNGFREGQVAKPRSK------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --SPRGAGYTFGQDISETFNHSNALTLISRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRC GNQAAIMELDDSLKYSFLQFDPAPRRGEPHVTRRTP----MGAYKYMQEIYRKKQSDVLR FLLRVRCWQYRQLSAVHRATRPSRPDKARRLGYRAKQGFVIYRVRIRRGGRKRPVPKGAT YGKPTNQGVNQLKFQRSLQNVAEERAGRRCGGLRVLNSYWVAEDSTYKFFEIIMVDPFHK AIRRDAKVNWICNSVHKHRELRGLTSAGKRSRGLGKGHKFNSTIGGSRRAAWKRNNTTSL RRKRGIAIGRLSEERKAWRKDHPFGFVAKPIKNPDSTLNLMNWECAIPGKKGTTWEGGLF KLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSLLDEEKDWRPAVTIKQILLGIQE LLNEPNAKDPAQAEAYTIYCQNKVEYERRVREQAMKYKDPSV------------------ -----------------NLILGDCDEFRKVRPKNSKSREEKRVLGLVLLRGENLVSMTVE GPPPAEEGIARVPIPGAGPGPGMGRAAGRGVP-GGGLQGPVRGVGGPSQQMMQPQGGMGR GGPP----SFKLVLVGDGGVGKTTFVKRHMTGEFEKKYVATLGVEVHPLVFHTNRGPVRF NVWDTAGQEKFGGLRDGYYIQGQCAIIMFDVTARVTYKNVPNWHRDLVRVCENIPIVLCG NKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPA LEPPEVQMDPNMARQYEAELEIAQQVALPDDADD-XXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXLSFAENFALSGAAAVISKTAAAPIERVKLLVQNQDEMIKQGRLAEPYKGVIDCTM KTYRSEGILPFWRGNLANCIRYFPTQALNFAFKDQIKALFKQSKNDSYGVKFSKNIASGG AAGAMSLFFVYSLDYCRTRLANDAKSAGKREFNGIIDVYKKTIKSDGVQGLYRGFVISCV GIIVYRGCYFGFYDTLKPMLLGPDAGLLASFALGYVVTISAGLVSYPIDTIRRRMMMTSG QAVKYKGSIDCTMQIMKNEGFMSLMKGAGANILRGVAGAGVLAGFDKFKELYVRWRLXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- ----------------------------------------ITVTCRDGRVAQLENVFIRG SKIRFLILPDMLKNAPMFKRVGAGRGKSAILRAAARGRGRA--------MQNEAGEYVDM YIPRKCSASNRIIQAKDHASIQLNIAEVDDSTGRMTGAHKTYAICGAIRRMGESDDCLIR LAKRDNVIAKMARGPKKHLKRLHAPKHWMLDKLGGVFAPRPSTGPHKMRECLPLMVFLRN RLKYALTYDESKKIMAQRLIKVDGRVRTDKTYPAGFMDVITIEKTAENFRLIYDIKGRFS VHRITGEEAKYKLCKIKRLSVGPKGVPFVVTSDGRTIRYPDPLVKVNDSVQV-------- --------------------------------KSTIGVEFATRSIQVDGKTIKAQIWDTA GQERYRAIXXXXXRGAVGALLVYDIAKHLTYENVERWLKELRDHADNNIVIMLVGNKSDL RHLRAVPTDEAKAFAEKNNLSFIETSALDSTNVETAFQNILTEIYKIVSQK--------- ----------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKRKPYSPFQVSNKVDFALA- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMVASKKAKK SIESINSRLALVMKSGKYVLGYKQTLKTLRQGKAKLVIIANNTPPLRKSEIEYYAMLAKT GVHHYNGNNIELGTSCGKYFRVTTLSITDPGDSDIIRSMPSEXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKVELCA FSGLKIYPGHGKRLVKIDGRNFQFINAKSERSHMMKRNPRKINWTVLYRRKHRKGQMEEV SKKRTRRTTKFQRAITGASLSDILAKRNQKPEVRKAQREQAIRAAKEKQKAKDKAQPRVG GKRMKLNVSYPATGCQKLIEVDDEHKLRSFYEKRMAAEVSAETLGDEWKGYIVRITGGND KQGFPMKQGILTNSRVRLLLSKGHSCFRPRRSGERKRKSVRGCIVDAQLSVLNLMIVKKG EQEIPGLTDKTVPRRLGPKRASRIRKLFNLSKEDDVRQYVVRRPLAPQTKAPKIQRLVTP LTLQRKRHRVALKRRRAAKKRDDAADYAKLLVQRLKEAKERKMERRRSASQSKKVKAKEL RGKKKEELLKQLEDLKQELLTLRVAKVTGGAASKLSKIHIVRKSIARVLTVINQTQKENL RKFYKPKDLRPKKTRAIRRALTKHEAALKTPKQLRKERLYPMRKFAVKDAASGPKVTDQV YFDIEIGGKAAGRIVIGLFGKTVPKTVKNFRTLAEGSKTYKGSKFHRVIKDFMIQGGDFT RGDGTGGRSIYFDDENFKLKHHGAGWLSMANAGKDTNGSQFFITTKMTSWLDGRHVVFGK VVKGMKVVRAIENSSTDGDRPTNAVVIKDCGVIEVDKPYTVEKKDAEEKKKKVVLKFTID CTHPVEDGIMDSASFEKFLHERIKVNGKTGQLKSKLIIQADIPFSKRYLKYLTKKYLKKN NLRDWLRVVANAKDSYELRYFQINNEEEEEEEGDXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTKTITLEELKKNSNAKSCWIAIHDKVYDVT KFLEEHPGGEEVLLEQAGKYGTESFEDV-------------------------------- --------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------ -------------------------------------TTGSNYYVRILSTIDRELLKPSA SVALHKHSNALVDVLPPEADSSITMLSADEKPDVAYSDIGGMDIQKQEVREAVELPLTHF DLYKQIGIDPPRGVLMFGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVR DVFRLAKENAPAIIFIDEIDAIATKRFDA------------------------------- ------------------------------------------------------------ -----------------------------------------------------PLSLDMI RERVLLVLKLYDKVDPEKLTVESHFMNDLGLDSLDTVEVIMAMEDEFGFEIPDSDAERLL TP---------------------------------------------------------- ---------------------------------------------QLRETQALVLSPTRE LATQIQKVILALGDYMSVQCHACIGGTNVGEDIRKLDYGQHVVSGTPGRVFDMIRRRNLR TRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVLLVSATLPHEILEMTSKFM---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------XXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGQDKTHINIVVI GHVDSGKSTTTGHLIYKCGGIDDRTIAKFEKEASEMGKGSFKYAWVLDKLKAERERGITI DIALWKFETTKFQVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQT REHALLAYTLGVKQLIVGVNKMDSTEPKYSKARFEEIKKEVSGYIKKIGFIPTAVAFVPI SGWHGDNMLNMEWFDGWKKASGKTLFNALDSINPPKRPTDKPLRLPLQDVYKIGGIGTVP VGRVETGVIKPGVIVTFAPSNVTTEVKSVEMHHTSMEKAEPGDNVGFNVKNVSVKDIKRG NVAGDSKNDPPKQADNFTAQVVVLNHPGQIHAGYTPVLDCHTAHIACKFVELKEKMDRRS GKKLEDNPKTIKSGDSAIVIMAPSKPMCVEAFTDYAPLGRFAVRDMRQTVAVGVIKAVEK KEGAGGKVTKSAQKA--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------ADQEIGMYSHDNIICGITSVAFSKSGRLLLG GYDDFNCNVWDTLKQERAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKIWNXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPKQ IMDIKDFLLTARRKDAKSVKIKKNVKFKVRCSRYLYTLVIQDREKAEKLKQSLPPGLAVK ELKMSKIPRDTLIDAVQTILKKKRNFTESVELQISLKNYDPQKDKRFSGTVKLRHIPRPK LRVCVLGDAQHCDEAKANSINCMDVEDLKKLNKNKKLVKKLAKKYNVFLASDSLIKQIPR ILGPGLNRAGKFPTLLTHSESMVSKVDDVKATIKFQMKKVLCLAVAVGHVSMAQDELVSN VNMSINFLVSLLKKNWQNVRALYVKSTMGPSIRVY------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------FFAKRQLVT LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLNAGRPVTPPRGQAKNK GKMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXX-------------------------RNGRKTLTTVQGINSEFDLKKI VKHCKKIFACNGTVVEHGEYGEVIQLQGDQRSRMQDMLCKSGMADQVKVHGFXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXSSRLTATLVRQLPRAVAKQNALGAGFVSCRNLSSSAEVSSILEERILGAPKANLEET GRVLSIGDGIARVYGLKNIQADEMVEFSSGLKGMALNLEPDNVGIVVFGNDKLIKEGDIV KRTGAIVDVPVGEALLGRVVDALGNAIDGKGPVDTDLRQRVGTKAPGIIPRISVRDPMQT GIKAVDSLVPIGRGQRELIIGDRQTGKTAIALDTIINQKRFNDATDEKKKLYCVYVAIGQ KRSTVAQIVKRLTDTDAMKYTIVVSATASDAAPLQYLAPYAGCAMGEYFRDNGKHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNENFGGGSLTALPVIE TQAGDVSAYIPTNVISITDGQIFLETELFFKGIRPAINVGLSVSRVGSAAQTKAMKQVAG SMKLELAQYREVAAFAQFGSDLDQATQNLLNRGVRLTELLKQGQYVPMAIEEQVVVIYAG VRGLLDKLDPSKITQFEAEFLQTIRNSHQDLLKDIREDGEISPANDEKLKGIVKSFVAGF MEALYSIPFSVFECPNLKIKKPTWIRQPSAMTTFSLILVSYFLVTGGIIYDVIVEPPSIG STTDERGNSKPVAFMPYRVNGQYIMEGLASSFMYLLGGLGMIVLDQTNKPLMPKLNRILM LSVGFVCVLVSFFTLRVFMRMKLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEYAQVIKMLGNG RLEAMCFDGTKRLCHIRGKLRKKVW----------------------------------- ------------------------------------------------------------ ---------TVKNKDPVQLDTLSIRGNNIRYFILPDSLPLDTLLIDDTPKARAKK----K PKSEMTPEELSQREQEEFNTGPLSVLTQSVKNNTQVLINCRNNKKLLGRVKAFDRHCNMV LENVKEMWSEVPKTGKGKKKSKPVNKDRYISKMFLRGDSVILVLRNP-PILIDARGHLLG RLAALVSKTILQGQRVVVVRCEEINISGNFYRNKLKYLDFLKKRCNVNPRRGPFHLRAPS KIFLRTVRGMVPHKLARGKDALSKLKVFEGIPPPYDKQKRMVVPSALKVLRLKPIRKFCR LGRLSHEVGWKYQNVVATLEAKRKLKSKAHYERTSTIAHMRKQAAKISKHQQVIESYGYA GNAEKGKKLFVQRCAQCHTVEANGKHKTGPNLHGLFGRKTGQAAGFSYTDANKSKGITWG RDTLFIYLENPKKYIPGTKMIFAGLKKKQERADLIAYLEASTK----------------- -----ILRSGFTILQKRRVHLTPEQASDFYAEHYGKLFFPSLVAYMSSGPVLTLVLSREK GISYWRELIGPTNTLKARQTHPDCLRAVYGTDDQRNALHGSDSYSSAAREIRFFFSDSIV EPVPVGQAARDYLAHTVNPILLKG-------------------------------XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXKSVAAYHTTNRTAVGRVVAVIGAVVDVQFDDELPPILNALEVQD RSPRLILEVSQHLGENTVRTIAMDGTEGLVRGQVCLDTGTAIKIPVGPETLGRIINVIGE PIDERGPVNSKHQLAIHQEAPEFINMSVEQEILVTGIKVVDLLAPYSKGGKIGLFGGAGV GKTVLIMELINNIAKAHGGYSVFAGVGERTREGNDLYHDMITTGVIDLKGNNSKVSLVYG QMNEPPGARARVCLTGLTVAEFFRDHEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIA ELGIYPAVDPLDSNSRILDRNVVGSEHYDVARGVQKILQDNKSLQDIIAILGMDELSEED KLTVSRARKIMKFLSQPFQMAEVFTGHPGKFVSLXQTIQGFKAILHGEYDHLPEVAFYMV GTVDEVVEKANRLAAEQMLMPKKNRVAIYEHLFKEGVMVAKKDFYAPKHPELDVPNLQVI KAMTSLKSRGYVNEQFAWRHYYWYLTNEGIQYLRDFLHLPPEIVPATLKRQAMGADRAEY RRGGGADKKADVGAGSTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX MTNTKGYRRGTRYMFSRKFRTKGHLPLSTYLKTYKRGDIVDIKGNGAVQKGMPYKAYHGR TGRIFNVTQHAVGVIVNKRVKGRILPKRINVRIEHVKHSNCRLEFLRRVERIEKLKKEGK ETVKVKREPAQPKPAQVVRTKYNKVQELQQIPYEFIA-----------------YSAMTD RAAGHMFFSELAKGMSVVVGQIFKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAICPAQAITIEAETRSDGSR----------------------------------- -------------------------------------MASPAKVAKPEGKNNHDNDKEQQ EAIEQIDDVQNEIDRLNENASEEILKVEQKYNKLRQPYFQKRSELIAKIPNFWVTAFVNH PQVSALLNEEDEEALQFLTKVEVQEF---------------------------------- ------------------------------------------------------------ -----------------KKLTKEEELLLQDFSRNVTTKSWALFYGNAFIVSAIPVWLFWR IHQMDPVILFVVMTLVSTYLVAFAYKNVKFLLKHKIAQKREEGVSRDVMRQVAEDKKMSR KEKDERVLWKKNEVADYEATTFSIFYNNALFLVLVILASFYVLRSFSPTINYVASMGTAG GLLALFSTSTKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXX------SIFGTEKDKVNCSFYFKIGACRHGERCSRLHNKPTFSQTVLLQN LYLNPQNTAQVHVTDVEVQQHYDDFFEEIFVELEQKYGEIEEMNVCDNLGDHLVGNVYVK ------------------------------------------------------------ ---------------------------------------------XXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------------ ------------------------------------------------------------ -----------------------------RFSKYMSNIKIAVFFGGVSIKKDEEVLKKNC PHIVVGTPGRILALVKTLNLKHIKHFILDECDKMLEQLDMRRDVQDIFRMTPHEKQVMMF SATLSKEIR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------FTTSGNQNQDTNKVGANLETKYKCSDYGLTF TEKWNTDNILATEITIEDQIAQGLKLTFDTSFAPQTGKKSGRIKSGYKREYLNLNCDVDF DFAGPTIHGAAVLGYNGWLAGYQMSFDKSKLAKSNFAVGYATDDFTLHTNVNDGSEFGGS IYQRVSSEFETGVSLSWTAGTNATRFGLGAKYTPDKETTFRAKINNSSQIGLSYQQKIRD GMTLTLSSLIEGKSFNQGGHKIGLGLDLE-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMTES LVSVVVKFYDEYMNSTSKKLKIIDAYLTYILLTGVVQFVYCALVGTFPFNSFXSGFISCV GSFVLGVCLRLQVNPQNKAEFLGISPERAFADFIFAHLILHLVVINFIGXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXMGKFMKSGKVVLVLGGRYAGRKAVIVKNYDEGTQDKQYGHALVA GIDRYPRVVTKRMGKKKMKQRSKIKPFVKVFNFNHLMPTRYSIVNLDKGVVNKDAFRDPA LRRKARREVKGKLEERYKTGKNKWFFQKLRFERTFIMVKPDGVHRGLVGETIKRFEQRGY KLVAIKFMQASTEHLEKHYADLSKMPFFPSLIKYMSSGPVVPMVWEGDAVKVGRMILGET KPVQSLPGTLRGDFCIQVGRNIVHGSDAVDSAKKEIDLWFKPEELVSWQICTDAWVHEVD APKPVKTSGKAKDKALKAKKSVLRGIHGKRQRKVRTSVHFYRPKTLRLTRQPKYPRKSTP RRNRFDQFKIVKFPLTTESAMKKIEDNNTLVFIVDKLANKHQIKLAVKQLYDIDVSKVNT LNRPDGEKKAYVRLAPDYDALDVANKIGIIMASKQRMRVASDKHSKNILTRGNVPKTLKP SEEKYPVGPWLLALFVFVVCGSAIFQIIQSIRFXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXGDTVFGKILRGEIPCKFIYQDEQVVAFDDLNPQAPVHFLVIPR KPIAMLSGDEQLLGHMLVAARKVAVEDDGYRVVINNGKNGCQSVYHIHIHVMGGRQLGWP PXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX X----------------------------------------------------------- ------------------------------------------------------------ ----------------QTEQVQKEQNYQRYREERFRQTSESTNTRVLWWSIAQTLILLVT GFWQMRHLKSFFEAKKLVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXRLYCKAVFTGFKRGLRNQHENTALLRIDGVQDIKSTQFYLGKKCAYVYKA KNKTANPGHSKSNHIRVIWGKVTRPHGNSGAVRAKFTSNLPPKAIGRRVRVMMYXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------- ----LDYHERKRKKEARSVHESATKAKKLRGLKAKLYNKKRHAEKVQMKKTLKMHEEKKT KQKSTEEVPDGAVPAYLLDREGQNRAKVLSNMIKQKRKEKAGKWDVPLPKVKGLGEAEVF KVVKTGKSRRKAWKRMVTKATYVGEGFTRKPPKYERFIRPMALRYKKAHVTHPELKATFC LPIIGVKKNPSSPMYTQLGVMTKGTVIEVNISELGLVTQGGKVIWGKYAQVTNNPENDGC INAVLLVMAARPLISVYSEKGESTDSNVTLPAVFRAPIRPDIVSFVHSEMRKNTRQPYAV SEQAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRR INVNQKRYAMCSAIAATGIPALVMSKGHRIEQIPEVPMVVSDKIEEYKKTKEAVGLLRRL KAWSDIEKVYSSKRFRAGKGKMRNRRRIMRRGPLVIYNQDNGICRSFRNIPGTTLINVNR LNLLKIAPGGHVGRFCIWTESAFKKLDAIYGTWRKPSAEKNHFNLPMPKMTNNDLARLLK SEEIQKALRAPKKDISRKVLKRNPLKNSRAMLKLNPFAAVQKKTAKRRTQRQTLRDQRRG IVTEKSGGKARPRKGAAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSHRKFSAPRHGSLGFLPKKRSKRIRGKV KAFPKDDPSKPIHLTSFLGYKAGMTHIVRDVDRPGSKQNKKETVESVTIIETPPMVVVGV IGYIETPHGLRSFKTIFAQHLSEECRRRFYKNWYRSKKKAFTKYSKKWQDEQGKKEIEKD FNKMKKYCKVIRIIAHTQMKLMKKRQKKAHMMEIQVNGGSIAQKVDWAREHLEKQVPIQD VFDADEMIDIIGVTKGKGFKGVTSRWHTKKLPRKTHKGLRKVACIGAWHPSRVSFSVARA GQKGYHHRTEINKKVYRIAKGIHTKDGKVVKNNASTQYDLTEKTITPLGGFPHYGEVNND FVMILGCCVGPKKRVITLRKSLMVHTSRKSMEKINLKFIDTSSKFGHGRFQTAQEKQSFM GPLKKDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXX------------------------------------------ ------------------------------------------------------------ ---VMKIGTKKTSFSNFAEICKLLHRKPKHLLDFLMAELGTSGSVDGNNQLIIKGRFQQK QIESVLRRYIKEYVT--------------------------------------------- --------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQVPESLLKKRKQNAAKNRIKRREMFKRAE KYIKEYRVKERDEVRLHRQAKKNGSFYVPAEPKLAFVIRHRGINGIHPRPRKIMQLFRLR QINNGVFVKLNKATLNMLRIADPYITWGYPNLKSVRELIYKRGYGKIEGKRLPLTDNALI EKKLGQYGIICIEDLIHEIFTVGPRFKEASNFLWPFKLNTPNGGWRIKNEHFVDGGDFGN REDKVSALLKKMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXAVLKYQMAVGLNKGYKVTKLKPKPSRRKGTLNKHVKFIRDIVR EISGFAPYEKRAMELLRISKDKRALKFCKKRLGAHIRGKRKREEMQATLQNMRKAXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------------- ------------------------------------------------------------ -------VYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEY ADQLGIPFLETSAKNATNVEQAFMTMAAEIKNRMGPVSTTPNVKINA------------X XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXKPPFKVADIELAAWGRKALELAENEMPGLMMMRRKYGKQKIL AGARIAGCLHMTVQTAVLIETLTELGAEVQWSSCNIFSTQDHAAAAIAKTGVPVYAWKGE TDEEYLWCIEQTLVFKDGKPLNMILDDGGDLTNLVHEKYPQYLEGIKGLSEETTTGVHNL YKMMAQGKLKTPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGRVAVVAGYGDV GKGCAAALRAFGSRVLITEIDPINALQAAMEGYEVTTMDEAVKEARVFVTTTGCKDIIHG YHFAQMLEDAIVCNIGHFDCELDVAWLNENCQSKENIKPQVDRYTMKNGRHIILLAEGRL VNLGCAMGHPSFVMSNSFTNQVLAQIELWTKAEQYKIGVHILPKKLDEEVAAAHLEHLGV KLTKLSEDQSSYLGIPKDGPFKPEHYRYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFRSALESFKSSPF ATPFGLKVNETREIQAA-DETSCEFGSAKYFALCGFGGILSCGLTHTAVVPLDLVKCRIQ VDAAKYGNIFQGFRITLAEDGARGLAKGWAPTFIGYSAQGLGKFGFYEVFKNVYSNLLGE EKTFLWRTSLYLAASASAEFFADIALCPFEAVKVRIQTQPGFANTLREGWPKIMETEGFN GFYKGLVPLWGRQIPYTMMKFACFERTVEALYKFVVPKPRADCTKSEQLVVTFVAGYIA- ---------------------GATFVGIAKSLGFGAMWKGLGPRIIMIGTLTALQWFIYD SVKVAFRLPRPPPPEMPESLKRKL-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GAPIIPISAQLKYNIEVICEYIYKKIPIPLRDFTSEPRLIVI RSFDVNKPGCEVDDLKGGVAGGSILRGVLKVGQEIEVRPGIVAKDNEGKLTCKPIFSRIV SLFAEQNDLQYAAPGGLIGVGTKIDPTLCRADRMVGHVLGAVGALPDIYTELEISYFLLR RLLGVRTEGDKKGAKVQKLSKNEILMVNIGSLSSGGRVLAVKADLAKIGLTSPVCTEIGE KIALSRRVEKHWRLIGWGQIRRGVTVKPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXMFLWDWFAGILNFLGLYKKSGKLVFLGLDNAGKTTLLHML KDDRMAQHVPTLHPTSEELTMGGMRFTTFDLGGHQQARRVWKDYFPAVDGIVFLVDAVDR ERFVEAKAELDSLLSDEQVAGAPVLILGNKIDVPGAASEEDIRHMFGLHGQTTGRGTVSR SELRPMELFMCSVLKRQGYGEGFRWLAQYINXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPNLPPISGEKL HGKSELRKIPVPSHRYTPLKENWMKIFSPVVDHLNLQIRFNLKSRNVELKTCKATKDVGA LQKG-XXXXXFMLGFEIEDSLALVRLDDLYLESFNVTDVKMLKGDHLARAVGRIAGKGGK TKYTIENVTKCRIVLADTKVHILGSFQNIRIARRAICNLILGSPPSKVYGTMRTIAARSA ER---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------IDDMVAQGLKSDGGFVWACKNYDGDVQSDVVAQGYGSLGLMTSVLMCPDGK TIEAEAAHGTVTRHYREHQKGNPTSTNPIASIFAWTRGLEHRAKLDNNADLARYCQVMEK ACIDTVESGKMTKDLAGCIHGLKNVKPEHYLYTMDFLDAIAENFDXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFGDLKSDSGLSVLNDFLADK SYIEGYVSSQADSAVFAALSGPKASFTHALRWYNHIKSY--DTSSLPGVKKALDQYGPAG TAAADDDDDIDLFGSEAEKLKQERLAAYAAKKSPTVIAKSNIILDVKPWDDETDMAELEK CVRTIEMDGL-------------------------------------------------- -----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--EFDLTTRMGQYLDRHLVFPLLEFLSVK EIYDEKEMLKGKLDLLSNTNMVDFAMDVHGSLYPDQDVPASLRDKRKNVVEELKRLQAQT DPIVKIFEDPEVMIHTSRDGKVLFDFLAKNYDFRPEMLDTLYTFAKFHYECGNYSGAAEY LYFVRVLVPPNDKNALSALWGKLASEILMQDWEAALEDLNRLKDVIDSALQSLQQRTWLI HWSLFVYFNHPKGRDLIIDMFLYQPQYLNAIQTMCPHILRYLTTAVITNKTVLKDLVKVI QQESYTYRDPITEFLECLYVNFDFDGAQQKLRECETVLVNDFFLVACLEDFIENARLFIF ETFCRIHQCISISMLADKLNMSPDEAERWIVNLIRNARLDAKIDSKLGHVVMGTQAVSPY QQVIEKTKGLSFRSQMLAMNIEKKL----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXX---LLGSVFAESTIHFKEEFWESRWVESTHKGAEA GKFKWSAGKFYGDADLDKGIQTSQDARFYGLSAKFENSFSNEGKDLVIQFTVKHEQNIDC GGGYVKVFSKDLDQKDMHGDSPYFIMFGPDICGPGTKKVHVIFNYKGKNHLVKKDIRCKD DVYTHLYTLIVRPDNSYEVKIDNEKVEGGELEADWDFLPAKKIKDPEAKKPEDWDENEKI PDPEDKKPEDWDKPEHIADPDAKKPDDWDDEMDGEWEPPQIDNPDYKGEWKPKQIDNPNY KGKWVHPEIDNPEYSPDSKIYSFNDIGVIGFDLWQVKSGTIFDNLMITDDVKAAEEHGNN TWGKTKDAEKKMKDAQDEEERKKKEEEEKAKKDTEKKDDE----XXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXX--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ LDPSIYESLQKEKVEAGDVIYIEANSGAVKRQGRSDTFATEFDLEAEEYVPLPKGDVHKK KDVIQDVTLHDLDVANARPQGGQDIMSMMGQLMKPKKTEITDKLRKEINKVVNK------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------DFEHDEEGDRGLQKL KEKARKRKGRGFSHSGGVQQYEAMETGGPGPQRSVEGWILFVTNVQEEAQEDDIKDKFGD Y----------------------------------------------------------- ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSFMFTSESVGEGHPDKICDQI SDAVLDAHLRVDPNAKVACETCAKTGMVMLLGEISSKAQVDYQKVVRDTIKHIGYDCSEK GFDYKTCNVLVALEEQSPDIALGVHVDRDEDNIGAGDQGLMFGYATDETEECMPLTVVLA HKLNAKIAELRRKGVLAWARPDTKTQVTCEYKIVNGACIPTRVHTIVISAQHSEEISLDD MRVELMEKVVKAVIPEKYMDENTVTHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAH GGGAFSGKDFSKVDRSAAYAARWVAKSLVKAGLCRRVLVQISYAIGVAEPLSITVFSYGT STKSEKELLQIVKNNFDLRPGRIVKDLNLKRPIYQKTASYGHFGRPEFPWEQAKKLAFXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMRLEKCYFCSSTVYPGH GIEFVRNDCKSFRFCRSKCHKAFKKKRNPRKTRWTKAFRKAAGKDLAVDPSFEFEKRRHV PVKYNRNLWNNTVNAMKRVEEIKIKRQNQFIINRLKKGKELRKEEDIREFKKNIHLIKSP AAR---YTVVMVRHGESTWNKENRFTGWYDSDLSPVGVTEAQTAGQMLKEKGYKFDVAFT SVLKRAIKTLYLIQEELDLHWIPVERHWRLNERHYGALQGLNKAETAAEHGEEQVKIWRR ----------------PGFDSRYALVDKRLIPTCECLQDTVARVLPYWYDVIVPAIKTGK KVLIAAHGNSLRAMVKYLDSMSDADIMGTNIPTGIPLVYELDEDLKPVKHYYLASEDQVK AAMDKVAAQGKAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXMGIDIRHNKLRKVHRTEPKSQDVYLRLLVKLYRFLARRTGA KFNKIVLKRLFMSKTNRPPLSIARLVRHMKKPGRENKTAVVVGTITDDVRILDIPKIKIC ALHLTERARARVLKAGGEIITFDQLALRSPKGKNSVLLQGPRKAREAYRYFGRAPGVPHS NTKPLVRSKGRKFERARGRRKSRGYKNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKARGTFKEYKIVGRRRPTEKERV PALYQMRIFAPDRVVAKSRYWYFVGMLKKMKKGTGEIVSVKQVHEKKPVSIKNVGIWLRY VSRSGQHNMYREYRDLTITGAVTQCYRDMGARHRARASAIQIMRVEEVPASKTRRANIKQ FHDSKIKFPLTHRVGRQLHRPRFTTSRPLTYYXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMAVQFTDGVVIGADSRTTTGAYIA NRVTDKLTPVTDNIFCCRSGSAADTQAIADIVSYHLNFHKMETGEAPLVKTAANIFRDLC YNYRDQLTAGIICAGWDKQEGGQVYTIPLGGMCQRQPFSIGGSGSTYIYGHVDATFREGM N-------------------------------------------------XXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMTSKDYYFDSYAHFGIHEEMLKDEVR TLTYRNSIYHNKHLFKGKVVLDVGCGTGILCMFAAKAGAKKVIGIECSGIIEHAQKIIKS NNLDDVISLVKGKVEEVSLPEGIDKVDIIISEWMGYCLFYESMLNTVIYARDKWLAPNGL IFPDRATLYVCAIEDRQYKDEKINWWDNVYGFDMSCIRKVAIQEPLVDVVDPKQVVTNSC LVKEVDIYTVKLEDLSFSAPFHLQCRRNDYVQALVTFFNIEFTKCHKRTGFSTAPDAPYT HWKQTDDYLTVKKGEELLGTITMNPNSSNNRDLDFNIAIDFKGELSQLDETMTFKMRMVK EDKTTWKSNYFMRIVQLMDEYPKCFIVGVDNVGSKQMQKIRISLRILMGKNTMMRKAIRG HMDNNPALEKLLPHIKGNVGFVFTKLDLVDVRNKILENKVAA------------XXXXXX XXLGPEKTSFFQALAIPTKIARGTIEILNEVHLIKVGDKVGASEATLLQMLKIYPFSYGL VILQVYDSGTIFSPEVLDIT---------------------------------------- --------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXX---------FARAAEKLYLSDPTKCRYVIKYKHNEGQLILKMTDDQVCLQYR TEHAQDIKKFEKLTSQLMRHMASKEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------- ------------------------------LRASITPGTVLILLAGRHKGKRVVFLKQLK SGLLLVTGPYHLNGCPLRRINQSYVIATKTKIDISGVKMPERVNDQYFRRKRQK--LQAK GDIFEFKKEEYSVSEERKQDQLEVDGQILDVVRKNAEKKSLFGYLGATFSLKNKQYPHTM VFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXX----------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------VFMFPAG LYFCFKKLTDANIFIIMYGTTSIYFAGVMVRLMLVLAPVMCILSGIAVSATLTTYMRNLD VSKKADSNYPVKNEVATAVVCLMTAFLITYTFHCTWVTSEAYSSPSIVLSARSGDGSRII FDDFREAYYWLRHNTPEDAKIMSWWDYGYQITAMANRTILVDNNTWNNTHISQVGQAMAS PEDKAYEIMRELD----------------------------------------------- ------------------------------------------------------------ ---------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQETFSLFDNRGDGRI YTHQIGEVLRAMGQNPTEAEVKKCNDPDSRVTFETFLPILSTISKNQSRCSIEEFVEGFK VFDKEQNGTINSAELRHLLTSLGEKLQDEEVEQLLQGQEDPQGNINYEEQI------XXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXX------------------------------------ ------------------------------------------------------------ ---------------------IIYAGDKAKFGQPEINIGTIPGAGGSQRLTRVVGKSLAM EMCLTGNPISAQVAKEAGLVSKIFPAAEVIGEAIKTAEKISAQSKLVMAICKEA------ ---------------------------------------- >Cirratulus_sp MTDRKAVIKNADMSEDMQQDAVDCATQALEEYNIEKDIAAFIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSG--TQLREFQTSAVRKDIDQAAKYIGAGAATV GVAGSGAGIGSVFGSLVIAYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLLLFAFX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX X--------------GSFQAELNEFFTRELAEDGYSGVEVRVTPTRTEIIILATRTQSVL GEKGRRIRELTSVVQKRFNFPPDTVELYAEKVSTRGLCAIAQAESLRYKLIGGLAVGRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGEPCNDYVDTAVRHVLLRQ GVLGIKVKIMLPWDPNGKIGPKRPLPDNVSIVEPKDEQLPQQPYSEQKGGKXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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------------------------------------------------------------ -----------KQTRAGQRTRFKAFVAIGDFNGHVGLGVKCSKEVATAIRGAIVLAKLSV VPVRRGYWGNKIGKPHTVPCKVTGKCGSVLVRLIPAPRGTGIVSAPVPKKLLHMAGIDGC YTSARGQTATLGNFAKATYAAIAATYSYLTPDLWKETVFTKSPYQEFTDYLMKMSGGLDV LALKEEDVAKFLACSTHLGATNADFQMESYVFKRKPDGVHIINLRKTWEKLLLVARAIAA IENPADVCVISARPYGQRAVLKFASHVGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDP RTDHQPVREASYVNIPVIAFCNTDSPLRFVDIAIPCNNKSIYSIGLMWWLLAREVLRLRG TISREVSWDVMVDLYFYRDPEEAEKE---------------------------------- -------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXX---SATSVGGTVRQRKAPAAGAGAAGMWRSYTEDSPG IKVGPVPVLVMSLLFIASVFMLHIWGKYTR-XXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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SGSSAEDVAKQ------------------------------------------------- ----------------------------------XXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRVIRSQRKGPGS IFKAHTKNRKGAAALRAVDYAERHGYIKGVVKDIVHDPGRGAPLAKVMFRDPYKYKMRTE TFVASEGMYTGQFVYCGKKASLQIGNILPVGMMPEGTIVCCLEEKMGDRGRLARASGNYA TVISHNPDTRRTRVKLPSGTKKVMPSDNRAMVGIVAGGGRIDKPMLKAGRAYFKYKAKRN CWPKVRGVATNPVEHPHGGGNHQHIGMASTVRRDTSAGRKVGLIAARRTGRLRG------ -XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------QNKPYPKSRFCRGVPDP KIRIYDLGRKKARVDDFPLCVHLVSDEYEQLSSEALEAGRICANKYLVKTCGKDAFHMRV RLHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQPIMSVRAREQHKANVI EALRRAKFKYPGRQKIYVSNKWGFTKWTQSDYEVMRADGRLIPDGVGVQYKPDHGPLKAW MDRQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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-----------------------------------EIEKEVTAYVKKVGYNPKAVAFVPI SGWHGDNMLNMPWYKGWAIASGKTLFNALDSILPPERPTEKPLRLPLQDVYKIGGIGTVP VGRVETGKIKAGMVVTFAPNRVTTEVKSVEMHHEQLAEGLPGDNVGFNIKNVSVKEVRRG NVCGDSKNDPPLEADNFTAQVIVLNHPGEIRQGYSPVLDCHTAHIACKFLELKEKIDRRS GKKLEDAPKAVKSGDAAIVNMKPQKPMCVEKFSEYAPLGRFAVRDMRQTVAVGVIKDVSK KEGGGGKVTKAAQKAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSYAYLF KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES FRSVTRSYYRGAAGALLVYDITRRDTFNHLTSWLEDARQHASSNMVIMLIGNKSDLEARR DVKKEEGEAFAREHGLIFMETSAKTAANVEEAFINTAKEIYQKIQDGVFDINNEANGIKI GPQHSPTNPSGGGGGSQGGGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX >Crassostrea_gigas --------ENADMSEDMQQXPVDCATTALEKYNIEKDIAAYIKKEF-XKYNPTWHCIVGR NFGSYVTHXTKHFIYFYLGQVAILLFKSG----TRQFRTTATRQDIDQAAKYIGAGAAAV GAAGSGSGIGTVFGSLIIGYARNPSLKNNLFTYAVLGFALSEAMGLFCFLLAAGILFAFM SHFKD-SKAPEAPIHRIRITLTSRNVKSLEKVCADLIKGAKEKSLKVKGPVRMPTKVLRI TTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADMDQVM QLVDPAKQFAKDSLRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNII V-ANPVSKKKKFVADGVFKAELNNFLTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVL GEKGRRIRELTSVVQKRFNFPEGTVELYAEKVAQRGLCAIAQCESLRYKLIGGLAVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPINDYVDTAVRHVLLRQ GVLGIKVKIMLPWDPSGKIGPKRPLPDHVSVVEPKDEAVPAHPYSEQKGAK----GRGGS AGGKFRISLALPVGAVINCADNTGAKNLFVIAVSGIKGRLNRMPAAGAGDMFVATVKKGK PELRKKVMPAVVIRQRKPVRRKNGVFIYFEDNAGVIVNNKGEMKGSAITGPVAKECADLW PRIASNASSIRKGKKEQIVLGPQVKEGENVFGVAHIFASFNDTFVHVTDLSGKETIARIT GGMKVKADRDEASPYAAMLAAQDVAEKCKTLGITALHIKLRATGGNRTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL-GKPRGLKTARKCVNHRRDQKWHDND YKKAHLPSRW-VKPFQGSSHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP NDGCLNYVEENDEVLVAGFGRKGHAVGDIPGVRFKIVKVANVSLLALFKGKKERPRSEGA ATIRTRKFMTNRLLCRKQMIVDVLHPGKATIPKTEVREKLAKMYKTTPDVIFCFGFRTKF GGGKTSGFGLIYDSLDFAKKFEPKYRLQRHGGRKQRKERKNRQKKVRGTKKAKVGA--RV PIKRSKTYTTPRRPFEKERLDQELKLIGEFGLRNKREVWRVKYTLGKVRKAARELLTLDE KDQRRLFEGNALLRRLVRIGVLDEGKMKLDYVLGLKLEDFLERRLQTQVFKLGLAKSIHH ARVLIRQRHIRVRKQVVNIPSFVVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGTT-- ---GEIFSQLFKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERITEAREELTRMLNEDELRD AALLVFCNKQDLPNAMNAAEVTDKLGLHSLRNRSWYIQATCATSGDGLYEGXHWLSNTLK NSKMPLAKDLLHPSLEEEKRTCKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRKKSHMVRMNVLADALKCIAAAEKKGKRQVLIRPCSKV IVRFLTVMMKHGYIGEFEIVDDHRNGKIVVNLTGRLNKCGVISPRFDISIRDMERWTTNL LPSRQFGFIVMTTSGGIMDHEEARRKHLGGKILGFFF-GRMHNPGKGISQSALPYRRSVP TWLKLTSEDVEEQIMKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKKKGMXPD LPEDLYHLIKKAVNIRKHMERNRKDRDSKFRLILVESRIHRLARYYKTKKVLPPNWKYES ATAAAMV-AVELPEIKLFGKWSSDDVQVSDISLTDYIAVKEKYAKYLPHSSGRYQVKRFR KSQCPIVERLTCSLMMHGRNNGKKLLTTRIVKHAFEIIHLLTGENPLQVLVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREASFRNIKTIAECLADELINAAK GSSNSHAIKKKDELERVAKSNRMAEQMTLRGTLQGHGGWVTQIATTPQYPDMVLSASRDK TLIMWKLTRDANYGLPFKCLKGHGHFVSDVVMSSDGQFALSGSWDKTLRLWDLSAGTTTR LFCDHEKDVMSVAFSADNRQIVSGSRDKSIKLWNTLGVCKYTIDEGHTDWASCVRFSPNT ANPIIVSCGWDKMVKVWNLTNCKLKTNHIGHSGYLNCVTVSPDGSLCASGGKDGQAMLWD LNEGKHLYTLDGGDVINSLCFSPNRYWLCAATGPSIKIWDLEGKIVVDELRQEVLSTNAQ APQCISLAWSADGQTLFAGYTDNLIRVWQVSMAARMREYKLVVLGSGGVGKSALTVQFVQ NIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTFNDLQDLREQILRVKDTDDVPMILVGNKSDLEDERVVGKLAKHFNCEFMETSAKKK INVNEIFCDLVRLINKKNPERMSEEKKDSSEHINLKVTGQDGSVVHFKIKKNTPLRKLMS AYCDRAGLKLGVVRFRFDGNPINETDTPSGLDMEDGDSIDVFQQQTGGMASLPMNPKPFL NGLTGKPVMVKLKWGMEYKGYLVSVDGYMNLQLANTEEYIDGAQTGNLGEVLIRCNNVLY IRGVEEEDEEGEMKDMSDAEGDDVPV--VSGGSMDVFTAVQEVLKTALIHDGLAKGLHEC AKALDKRQAHLCILANNCDEPMYVKLVEALCAEHGINLMKVDDNKKLGEWAGLCKIDKEG KARKVVGCSCVVVKDYGKESQALDVLNDYFRSKKMAAIRKKLVIVGDGACGKTCLLIVFS KDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSI DSPDSLENIPEKWTPEVKHFCPSVPIILVGNKKDLRNDESTKRELMKMKQEPVRPEDGRA MAEKINAYGYLECSAKTKEGVREVFENATRAALQTKKKKKGIMDEFQTGEETAFVTDEVT NIVKEAIESTIGPNAYQHNKVNQWTSNVVEQCLNQLTKLGKPFKYIVTCVIMQKNGAGLH TASSCFWDNGTDGSCTVRWENKTMYCIVSVFGLAI------------------------- -------------------------------------VPVPQLRAYQKIQTRLVRELEKK LSGKHVVFIAQRRILPKPTRKTR-KSKQKRPRSRTLTAVHDAMLEDLAFPAEIVGKRIRI KLDGSRLIKVHLDKNQQTNIEHKVDTFSAVYKKLTGKDVVFEFPEFVLGRGGFRGGFGGR GRGRGRGRGRAKEGEKEWMPVTKLGRLVKDQKIKSLQEIYLFSLPIKEFEIIDYFLGPSL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDHDGHVGLGVKCSKEVATAIRGAIILAKLTV IPVRRGYWGNKIGKPHTVPCKVTGKCGSVVVRLIPAPRGTGIVSAPVPKKLLQMAGIDDC YTCARGCTATLGNFAKATYAAIANTYSYLTPDLWKETAFTKSPYQEFTDYLAKMSGGLDV LALGEDDITKFLACNTHLGATNVDYQMEQYVFKRKPDGVYILNLRKTWEKLLLAARAIAA IENPADVCVISARPYGQRAVLKFASATGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDP RTDHQPVTEASYVNIPVIALCNTDSPLRYVDIGIPCNNKGLHSVGLMWWLLAREVLRLRG TISRDHPWDVMVDLYFYRDPEEAEKEQEVTDWASEAMVAPAPQTAKDWSA-TTDDWSAAA SAPEWGGMKFNKMVTSSRRKNRQRHFNAPSHIRRKMMSSPLSKELRQKYNVRSMPIRKDD EVQVVRGHYKGQQVGKIVQVYRKKFVVYIERIQREKANGASVHVGIHPSKVVIVKLKIDK DRKRILDRKARSRQIGKHTEESVAPASSTSVGSTVRQRKTPSSGGSGAGMWRFYTEDSPG IKVGPVPVLVMSLIFIASVFMLHIWGKYTRGSKKGD-KKVLTEVITKECTIHMHKRIHGI GFKRRAPRAIKEIRKFAEKMMGTPDVRVDTRLNKHIWSQGVRNVPYRVRVRLARKRNEDE DSVHRLYTLVTYVPCASFKGTQTINVDN-------------------------------- ---------------------------KILQGGVGIPHIRWYGEKDYNILVMDLLGPSLE DLFNFCSRRFTMKTVLMLADQMIGRIEYVHNKNFIHRDIKPDNFLMGIGRHCNKVFLIDF GLAKKYRDS--------------------------------------------------- ------------------------------------------------------------ ------------------------------MNPEKLKQRIGGKGTARRKKKVVHRTATTD DKKLQSSLKKLSVNNIPGIEEVNMIKEDGTVIHFNNPKVQASLAANTFAITGQAENKQIA EMLPGILNQLGAESFSSLKKLASSTEDIDEDDDGVPELVGNFDETSKGEMVRYATEPDNP TKSAKARGSYLRVHFKNTRETAQAIKRMHVKRATKYLKNVMAKKEVVPFRRFSGGVGRCA QAKAFKHSQGRWPKKSAEFLLQLLKNAESNAEYKGLDTDHLVIEHIMVNAAPKMRRRTYR AHGRINPYMSSPCHIELILAEREQAVPRPVKKKVSQKKLKRQKMMMRDKKGGPKPELTDE QRQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMIADIDKEGSGTIDYND FQNIMTQKMSEKDLKEEIQKAFRLFDDDDTGKISFKNLKRVSKELGENLTDEELQEADRD GDGEINEQEFLKIMKKTSLYMGISRDKWHKRRKTGGRMTQIRKKRKFELGRPAANTKLGN RRIHSVRTMGGNKKYRALRLESGNFAWGSEAITRKTRIIDVVYNASNNELVRTKTLVKSC IVQIDATPFRQWYEAHYAKPLGRKAGVKLAEKEEAVLKTASKKTKRKYAEREKLAKVEHA LDDQFSAGRVLAKVASRPGQCGRCDGYILEGKELEFYQRKLKTKKGKMALILPEKFQHIL RILNTNIDGRRKIMFAMTAIKGIGRRYANVVCKKADVDITKRAGELSEEEIDKIVTIMQN PRQYKIPDWFLNRQKDIKDGKFSQVMSNTLDNKLREDLERLKKIRAHRGLRHYWGLRVRG QHTKTTGRRGRTVGVAKKK-SGTESDSDDDVPELEDVAAAAGIPEELVSKAKQSRSEKKA RKAMSKLGLKQIQGVTRVTIRKSKNILFVINRPDVYKSPASDTYIVFGEAKIEDLSQQAQ MAAAEKFKTEGEVDETGVESKDIELVMSQANVSRSKAVKALRNNSNDIVNAIMMARVRTK TVKKAARVIIEKYYTKLTLDFHTNKRVCEEIAILPSKKLRNKVAGFVTHLMKRIQRGPVR GISIKLQEEERERRDNYVPEISYIDEVDPDTKEMLKALDFGNLQGLQVTQPITAVMKWEY KEEHSFEKRRAEGEKIRKKYPDRVPVIVEKAPKARVGDLDKKKYLVPSDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGSLYQEHHEEDFFLYIAYSDESVYGMRELRIQKL CLNICVGESGDRLTRASKVLEQLTGQQPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAE EILERGLKVREYELKKNNFSDTGNFGFGIQEHIDLGIKYDPGIGIYGMDFYVVLSRPGFN IAYRRQRKSKIGPQHKISKEEAMKWFQQKYDGIILPGK---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --TGILLAVTIIYQYFEIFVKEQSEMGGMSTLLFQTERSFQKQPTVFLNNKKNLMTRHFK SVGLGFRTPREAMLGTYIDKKCPFTGNVSIRGRILTGVVQKMKMQRTIVIRRDYLHYVKK YKRFEKRHRNMSVHLSPCFRDVEMGDIVTVGECRPLSKTVRFNVLKVSKGGASKKGFKKY MVNVPKSRKTFCKGKKCKKHTLHKVTQYKTGKASLYAQGKRRYDRKQSGFGGQTKVIFRK KAKITRKIVLRLECTECKYRKQLAIKRCKHFELGGEKKRKGQMIMFMGRVIRTQRKGPGG IFKARTKNRKGKAALRAVDFAERHGYIKGVVKDIIHDPGRGAPLAKVVFRDPYRFRLRTE TFVASEGMYTGQFLYCGKKANLQIGNILPVGTMPEGTIVCCLEEKMGDRGKIARASGDYA TIISHNPDTKKSRVKLPSGAKKLIPSANRAMVGIVAGGGRIDKPMLKAGRAYFKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGKASTVRRDTSAGRKVGLIAARRTGRLRGT----- -AKRTKKVGICGKYGTRYGASLRKTIKRMEVSQHSKYTCQFCGKDAMKRKAVGIWSCSRC RKTVAGGAWVYSTTAAATVRSAVRRLREMKEMGRRPARCYRYCKNKPYPKSRFCRGVPDP KIRIFDLGRKKARVDEFSLCVHLVSDEYEQLSSEALEAGRICANKYLVKNCGKDAFHMRI RVHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQPIMSVRARENHQASVI EALRRAKFKFPGRQKIHISKKWGFTKWEKPQYEEMRADGRLIPDGVTVQYKPEKGPLKAW MDRQEVLKVLGRTGSQGQCTQVRVEFLDDSNRSIIRNVKGPVREGDILTLLESEREARRL RMTKGTSSFGKRHNKTHTACRRCGRRAYHIQKKTCASCAYPSPKRRHFEWSEKAKRRRTT GTGRMRYLKTVQRKFRNGFREGTTPKPRKR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AAIMELDDSLKYSFLQFDPAPRRGEPHVTRRTPDYFLMGAYKYMQEIYRKKQSDILR FLLRVRSWQYRQLSSCHRAPRPTRPDKARKLGYKAKQGFVIYRVRVRRGGRKVPVPKGIT YGKPTTSGVNQKKFQRSHRSIAEERVGKKCGGLRVLNSYWVAQDSSYKFYEIIMVDIFHK AVRRDPKLQWICNPVHKHRELRGLTSAGKMSRGLGKGHRYTKTIGGSRRAAWKRNN---- ----GIAIGRLSEERKAWRKDHPFGFVARPAKNPDGTLNLLNWECAIPGKKGTPWEGGLY KLRMLFKEDYPSSPPKCKFEPPLFHPNVYPSGTVCLSLLDEEKDWRPAVTIKQILLGIQE LLNEPNVKDPAQAEAYTIYCQNRVEYERRVRDQAVRFRDPSLGRSSKMLQHINYRMRCAL QDGRTFIGTFKAFDKHMNLILGDCDEFRKIKPKSSKQREEKRVLGLVLLRGEHLVSMTVE GPPPAEEGVARVPLAGAAPGQGMGRAAGRGISGPGGLQGPARGVGGPSPQMMAPG-GMMR GGPPDQIPTFKLVLVGDGGVGKTTFVKRHVTGEFEKKYVATLGVEVHPLKFHTTRGEIIF NVWDTAGQEKFGGLRDGYYIQGQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCG NKVDIKDRKVKAKAIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLVGDANLEFVAMPA LAPPDIKMDPNLAAQYEQELQAAVEVALPDDDDDLHEGIKQYYISKIEELQLVVTDKTQN LRRLEAQRNELNAKVRMLREELQLLQEQGSYVGEVVKPMDKKKVLVKVHPEGKFVVDIDK NIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEI KEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ KFIGEGSRMVRELFV--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----LSFAENFALSGAAAIISKTAAAPIERIKLLVQNQDEMLKAGRLSEPYKGVIDCTV RTYKTEGFLPFWRGNMANCIRYFPTQALNFAFKDKIKQIFKASKQDSYMLGFAKNIGSGG LAGAMSLCFVYSLDYCRTRLANDAKSAGKRQFNGMVDVYRKTIASDGVAGLYRGFVISCV GIIVYRGCYFGFYDTFXQILLGDNASVLLSFALGYVVTISAGLVSYPIDTIRRRMMMTSG EAVKYKGSLDCAMVIIKNEGFMSLMKGAGANIXRGVAGAGVLAGI--------------- -SDLDRQIEQLRRCEVIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLK ELFKVGGDVPNTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQV YGFYDECLRKYGSITVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLNQIRAINRK QEVPHDGPMCDLLWSHPEDMQGWGVSPRGAGYPFGHDVVAQFNAANSIELICRAHQLLME GYN-HFRETVLTVWSAPNY-YRCGNVAPILELYEHLDRDFTIFEAAPQESRGKPQPDYFL VRLPPEVNRILYVRNLPYKITAEEMYDIFGKYGAIRQIRVGNTTETKGTAFVVYEDIFDA KNACDHLSGFNVCNRYLVVLYFQPNKAFKKTDDNKKKEDIDKMKQKYGLSTPEKKMSIGV PIKVLHEAEGHIVTCETTTGEVYRGKLVEAEDNMNCQMSAITVAYRDGRVAQLENVYLRG SKIRFLILPDMLKNAPMFKRVSANRGKSAILRTAARGRGRGGPGGPRGGMQNETGEFVDM YIPRKCSASNRIIAAKDHASIQINIADVDPTTGRMTGSNTTYAICGNIRRMGESDDSLIR LAKRDHLI----RGRKKVLKRLTAPKSWMLDKLGGVFAPRPSTGPHKLRESLPLIVFLRN RLKYALTYDEVKKITMQRLIKVDAKVRTDKNFPTGFMDVISIEKTNENFRLLYDVKGRFT VHRIQKEEAKYKLCRVRKVGVAAKGVPYITTHDGRTIRYPDPLVKVNDTVMLMGTKDDEY DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTA GQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADNNIVIMLVGNKSDL RHLRAVPTDEAKAFAEKNNLSFIETSALDSTNVETAFQNILTEIYKIVSQKQIRDSPDDN NVQTIHVGPT------------MSSRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVR GNNIVVLGVEKKAVAKLQEDRTVRKIALLDDHVALAFAGLTADARILINRARVECQSHKL TVEDPVTLEYITRYIAQLKQKYTQSNGRRPFGLSALIIGFDGTPHLYQTDPSGTYHEWKA NAIGRSAKPVREFLEKSYTDEVANQEECIKLALKALLEVVQSGAKNVELAVMRDKEPLKM LELEEVEKYIAEIEKEKEEEAEKKKQK--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------THPEYYEEMGIKPPK GVILYGPPGTGKTLLAKAVANQTSATFLXVVGSELIQKYLGDGPKLVRELFRVAEEHAPS IVFIDEIDAVGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVVMATNRIETLDPA LIRPGRIDRKIEFPLPDEKTKRRIFTIHTNRMTLAEDVNIDDYVMAKDDLSGADIKAICT EAGLLALRERRMKVTNEDFKSAKENVLYRKNEATPEGLYLXREXYSPHQHENNMDFVMAR ADDLLNWGRRTSIWPMTFGLACCAVEMMHFAAPRYDMDRFGIVFRASPRHCDVMIVAGTL TNKMAPALRRVYDQMPNPRWVISMGSCANGGGXYHYSYSVVRGCXRIVPVDIY------- ------------------------------------------------------------ ------------------------------------------------------------ ---FTTSKIGSLVDVNQSKDPEGLRTFYYLVQDLKCLVFSLIGLHFKIKPI----KKSKK TIENINSRLALVMKSGKYVLGYRQTLKTLRQGKAKVVIIANNTPPLRKSEIEYYAMLAKT GVHHYTGNNIELGTACGKYFRVCTMSITDPGDSDIIRSMPSTMTEYKLVVVGAGGVGKSA LTIQLIQNHFVEEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGF LCVFAVNSTKSFEDINQYREQIKRVKDADEVPMVLVGNKVDLQTRTVESKQAKQVADSYN IPYVETSAKTRQGVDDAFYTLVREIRKFMGDRYNIHSQLEHLQSKYIGTGHADTNKWEWL TNQHRDSCASYMGHADMLNYFALAENESKARVRFNLMERMLQPCGPPPERPEDMKIELCS YSGYKIYPGHGKRIVKVDGRVFQFLNGKCEASHKMKRNPREINWTVLYRRKHKKGNLEEI AKKRTRRTTKFTRAVTGLSLAEIQAKRNQKPEVRKAQREQAIRAAKEKQKAKDATKPRVG GKRMKLNISYPATGCQKLIEVDDEKKLRPFYEKRMASEVPADSLGDEWKGYVLRIAGGND KQGFPMKQGILTNVRVRLLLSKGHSCFRPRRTGERRRKSVRGCIVDSNLSVLAMVIVKKG EKDIPGLTDTTIPRRLGPKRASKIRKLFNLSKEDDVRQYVVRRPLPAKTKAPKIQRLVTP VVLQRKRHRLALKKKRHSKRREDAAEYAKILAQRLKEAKERKRSRSNS-----KVKAKEL RGKKKEDLEKQLDDLKQELGTLRVAKVTGGAASKLSKIRVVRKSIARVLTVMHQTQKENL RKYYKPTDLRKKKTRAMRRALTPFEKSIKSRKQQRRERLYPMRKFAVKDKTKGPKVTDKV YFDISIGGEDAGRIVIGLFGKTVPKTVKNFKTLAEGTETYKGSKFHRVIRDFMIQGGDFT RGDGTGGRSIYFADENFKLKHYGAGWLSMANAGKDTNGSQFFITVKKTEWLDGRHVVFGK ILEGMDVVRKIENNPTAGDKPVKEVEIXDCGSLPVDSPFAVEKEDAK-KKKKTSLRYTID CTHPVEDGIMDVGNFEKFLQERIKVNGKTGNFKNKINLTSDIPFSKRYLKYMTKKYLKKN NLRDWLRVVANNKESYELRYFQINNEDEEEDEDESKDDKGDEEKTYGGCEGPDAMYVKLV SSDGHEFIVKRDHALTSGTIKAMLSGPGQFAENETNEINFREIPSHVLQKVCMYFTYKVR YTNSSTEIPEFPIAPEIALELLMAANFLDC-KIYRESEVTG-KKDKSTWLIIHDNVYDVT KFLEEHPGGEEVLLEQAGRDATEAFEDVGHSNDARELMKDYLIGELHPDDKGNWTGWLLP LGVALAAAFVYRYF---MLQHLHNGWQVDQAILAEEDRVVVVRFSHDWDPSCMVMDETLY KCAEKMKNFAVVYLVDTSEVPDFNKM-------TVMFFYRNKHIMIDLGTGNNNKINWSM ADVQEFIDIVETVFRGARKGRGLVISPKDYSTK--------------------------- ----LHAQEEVKRIQSVPLVIGQFLEAVDQNTGIVGSTTGSNYYVRILSTIDRELLKPSA SVALHKHSNALVDVLPPEADSSITMLQADEKPDVQYADIGGMDIQKQEVREAVELPLTHF DLYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAASIRVVGSEFVQK---------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------GKNVYTIEEV EKRVMITLQLFDKIDPEKLTKDSHFIKDLGLDSLDQVEIIMAVEDDFDFEIPDDDAERLM TPALIIEYICDKEDTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIPLRRP FDPAAHELDASFRLTKFADLKGGCKVPQEALEKLLEGL-QAQESEQSHFQYIAAAPRIGI GMDASVTPLRHGGLSLVQTTDFFYPLVDDPYMMGKISCANVLSDLYAMGVTDTDNMLMLL GVSNKMSEKERDIVVPMMMRGFKDQAEEGGTAVTGGQTVINPWMTIGGVATTVCQSNEFI MPDNAVVGDVLVLTKPLGTQVAVNAYQWLDQPERWNRVKLVVTEDDVRKAYQRAMFSMAR LNRTAARLMHKYNAHGATDVTGFGLLGHAKNLAKIQKNEVSFVVHNLPIIAKMASISKAC GNMFGLLQGHSAETSGGLLMALPREQAAAFCKDIEKQEGYQSWIIGIVEKGNRTARIIDK PRVIEVPAKDRD-----------YFINIDAHAEECFFDKVTSGTKMSLMFEVAEGGFLDI DVKIYGPDGKVIHQGDRESNGKYTFAAHMDGVYRYCFNNKMSTVTPKILMFTMDIGEKPK ANHNKLTEMINELSTALTGVKHEQEYMEVRERIHRAINENTNSRVVLWSFFEALVLVAMT LGQVYYLKRFFEVRRVV--ATLKPYLDAIRHTLTAGFSLQNFDSQVVERHNKPEVEVKSS KELLLTPVTISRNEKEKVLIEGSINSLRISITIKQADDIEKILCHKFMRFMMMRAEHFTV LRRKPVEGYDISFLITNTHTEQMYKHKLVDFIIHFMEEIDKEISAMKLAVNSRARISAEE FLKRFSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLV TMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTMPNTFKSLDSWRDEFLIQASPRDPEN FPFVVIGNKIDLENRAVTAKRAQSWCTSKGEIPYFETSAKEAINVEQAFQTVAKNALAQE TEVDLYNEFP----------------TAKFDARFQMCNQDKACWQNYVDYFRCIKKEDYE PCNWFKKQYQALCPGFWTERWDEQREAGAFPAKIMPDHLGADQRKTKEDKDEDKPIQALD EGDIALLKTYGVGQYSKAIKSVEEDIQNGVKKVNELAGIKESDTGLAPPALWDLAADKQT LQNEQPLQVARCTKIINADSDDPKYIINVKQFAKFVVDLGDQVAPTDIEEGMRVGVDRNK YQIHIPLPPKIDPSATMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGI EPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARN KKACIIFFDEIDAVGGARFDDGACGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDT LNPALMRPGRLDRKIEFGLPDLEGRSHIFKIHARSMSVEKDIRYELLARLCPNSTGAEIR SVCTEAGMFAIRARRKMATEKDFLEAVNKVIKAYAKFSSTPRYMTYNMGKEKTHINIVVI GHVDSGKSTSTGHLIYKCGGIDQRTIQKFEKEAAEMGKGSFKYAWVLDKLKAERERGITI DIALWKFETTKYHVTIIDAPGHRDFIKNMITGTSQADCAVLIIAAGTGEFEAGISANGQT REHALLAFTLGVKQLIIGVNKMDSTEPPYSEARFNEIKGEVEKYIKKIGYNPKAVPFVPI SGWHGDNMIKMDWFKGWAIASGKTLLEALDSILPPKRPTDLPLRLPLQDVYKIGGIGTVP VGRVETGIIKPGMVVTFAPPNITTEVKSVEMHHESLPEAVPGDNVGFNIKNVSVKEIRRG NVCGDSKNDPPKGAKNFLAQVIILNHPGEIKNGYAPVLDCHTAHIACKFVEIKEKCDRRS GKVLEEAPKCIKNGDAGMVLMVPSKPMCVEAFSKYAPLGRFAVRDMRQTVAVGVIKEVEK AEPSQGKVTKAAQKA--------------------------TLASATANVEPVGRIQMRT RRTLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAP SGSYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDNQIVTSSGDMTCA LWDIETGQQTTAFTGHTGDVMSLSLSPDMRTFVSGACDASAKLWDIRDGMCKQTFSGHES DINAITYFPNGYAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLG GYDDFNCNVWDVLKQDRAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKIWNMSYAYLS KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES FRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLEARR DVKKEEGEAFAREHGLIFMETSAKTAANVEEAFINTAKEIYQKIQDGVFDINNEANGIKI GPQHSPS-PSSSGGGAQGSGMTRGNTELGDITPHNIKQLKLLNQVVFPVTYNDKFYKDVL EVGELAKLAYFNDIVVGAVCCRVDTSDQQRRLYIMTLGCLAPYRRLGIGTSMVEHVLKIC EEDNNFDNVFLHVQINNDGAIRFYEKFGFEIVEEKKNYYKRIEPADAYVLQKSFRKMPKQ IQEIKDFLLTARRKDAKSVKIKKNVKFKVRCSRYL------------------------- ---MSKINRDNLNDSISAILQKPRKFTQSVELQIVLKNYDPQKDRRFAGTVRLRTVPRPK MKICILGDQIHCDQAKANNLPCMTADDLKKLNKDKKLIKKLAKKYDAFLASDSLIKQIPK ICGPGFNRVGKFPTQVSHQESLVQKVEEVKGTIKFQLKKVLCLATCVGHVNMTKEELYGN ITLAINFLVSLLKKNWQNVRALYIKGTMTPAQRVYXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEIVGTNVSTT YITCPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPF ICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDEL PAEFKLYLPVQNK----------DPFKEASTIHIRIQQRNGRKTLTTVQGISTDYDLKKI VKACKKEFACNGTVVEHPEYGEVIQLQGDQRNRIRDFLRDIGIEEQLKVHGFSALFNFQS LLTVVLLLICTCAYIRSIAPRLLDKNKTGVLGTFWKCARIGERLSPYVAVSCVGMAIVIL FFT--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------TIIVSATASDAAPLQYLAPYSGCAMGEFFRDNGMHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDDHGGGSLTALPVIE TQAGDVSAYIPTNVISITDGQIFLETELFFKGVRPAINVGLSVSRVGSAAQTKAMKQVAG SMKLELAQYREVAAFAQFGSDLDQATQNLLNRGVRLTELLKQGQYVPMAIEEQVTVIYAG VKGHLDKIDPSRITQFEAEFLDHVKGHQQEMLTQIRKDGQITEATDAKLKEVVTTFLAGF MEAIFSIPFTVLEVPNLKLKRPXWVKQPSAMVMFSMVLFSYFLVTGGIIYDVIVEPPSIG STTDERGNSKPVAFMPYRVNGQYIMEGLASSFLFTIGGLGFVILDRTNH-SMPRLNRILL ISVGFISILISFFMCRVFMRMKLPMPKVKRSRKPPPEGWELIEPTIDELDAKMREAETDP HEGKRKVEALWPIFRLHHQKSRYIYDLFYRRKAISRQLYEYCLKENIADKNLIAKWKKQG YENLCCLRCIQTRDTNFGANCICRVPKSKLEAGKIVECIHCGCRGCSGEYAQVTKMLGNG RLEAQCFDGVKRLCHIRGKLRKKVWINGGDIILLGLRDFQDTKADVILKYTADEARNLKA YGELPESTRINEEDEHDIEFDEIDELXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--LAK PKSEMTPEELSQREQEEFNTGPLSVLTQSVKNNTQVLINCRNNKKLLARVKAFDRHCNMV LENVKEMWTEVPKTGKGKKKSKPVNKDRYISKMFLRGDSVILILRNPMPILIDARGHLMG RLAAIVAKTVLQGQRVVVVRCEGINISGNFYRNKLKYLKYLRYRCNVNPSRGPFHYRAPS RIFFKAVKGMIPHTTTRGKDALGRLKVFEGVPPPYDKQKRKVVPAALRILRLKQNRRFCD LNGLAHEVGWKYQGVIGTLEAKRKARSKKFYENRKVADNLKAKARKIAQYQKVIEGYGYA GDVDKGKKVFVQKCAQCHTVEAGGKHKTGPNLNGLFGRKTGQAAGFSYTDANKSKGITWG KDTLFEYLENPKKYIPGTKMVFAGIKKAQERGHLIAYLESSTKIYVERTLAIVKPDAISE EIEDIILRSGFAILQKRRVHLTPEQASDFYAEHYGKMFFPSLVAYMSSGPVLAIVIARDQ AISYWRELIGPTNALKARQTHPDCLRAVYGTDDQRNALHGSDSFSSSEKEIRFFFPDSVI EPVPVGQAAKDYLAKSVNPCLLKGLTELCKQKPIDPVIWLADWLLENNPNKPKVRMFEAR LVQGSLLKKLMEAIRDLIPEAIWDCSGTGITLQAMDNSHVALVAVNLRSDGFETYRCDRN LSMGMSLASMSKVLKCASNDDVITLKAGDNADTVTFMFESPNNEKVSDYSLKLLDLDCEQ LGIPDTEYSCVVKMPSHEFQRICRDLSRIGESMVICCTKEGVKFSASGDLGTGNVKLAQN ASADKEEEAVIIEMNQAVTLTFALRY---------------------------------- ---------------------------APPGRVVAVIGAVVDVQFDDALPQILNALEVKD RQPRLVLEVAQHLGENVVRTIAMDGTEGLVRGAQCIDTGYPIRIPVGRGTLGRIINVIGE PIDERGPVKTDTVLPIHAEAPAFTEMSVEQEVLETGIKVVDLLAPYSKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMITSKVISLTDDTSKVSLVYG QMNEPPGARARVALTGLT------------------------------------------ ---------------------------QAIYVPADDLTDPAPATTFAHLDATPVLSRGXA ELGIYPAVDSLDSNSRILDVNVVGERHYRVARGVQKILQDFKSLQDIIALLGMDELFEED KLTVVRARKIQKFLFLPFQVGEVFPGQEGKYVPLKETLTGFERVVNGEYDHIPEVGFYMV GPIAEVDQKAARVAEEQMLMPKKNRVQIFEYLFKEGVLVAKKDFSAPKHPEIDVPNLHVI KALTSLKSQGYVREQFSWRHYYWYLTNEGIQYLRDYLHLPAEIVPATLKRQPGAQDRAEY RRAAGGDKKTESGAGADMGKQNSKLKPEVLADLNLNTNFNKEEIQEWYKGFIKDCPSGSL SIEEFKSIYSELFPLGDASKFAEHVFRAFDENKDGTLDFREFMCALNVSSRGTLEQKIHF AFRIYDLDGDGYISKNEMCEIIKAIYKMVGPAMKDDEQEQTPEXRTEVLFEKMDKNMDKL LSLSEFIEGVKGD-----------MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNL TGLNEQVPHYRQALDMILDLEPDDELEDNPNQSDLIEQAAEMLYGLIHARYIMTNRGIAQ MIEKWQQGDFGACPRVYCENQCMLPIGLSDVPGEAMVKLYCPKCQDVYTPKSSRHHHTDG AYFGTGFPHMLFMVHPEYRPKRPANQFVARLYGFKIHPLAYNLQYQAASNFK-------- MTNTKGYRRGTRYMFSRPFKKHGVIPLSTYMLNYKRGDIVDVKGHGAVQKGMPHKFYHGK TGRVFNVTKHAVGVIINKRVRERVIPKRINVRIEHVKHSNCRLEFLKRVANNEQAKKAAK ERKNLKRFPELPRKKHFVSTKYNKPEVLEPIPYEFIA--RNKYVIVSKKEPEVTFEAMTD RFVFYTFLQEIIAGGRTVLGMLFKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAICPAQAITIEAETRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEY STETHEELLYNKEKLLSNGDKWEVEIAANLQADYMYRMATPAKVSKPEGKNNHDNDKEQQ EAIEQIDEVQNEIDRLNEQASEEILKVEQKYNKLRQPYYSKRSDLIAKIPNFWVTAFVNH PQISALLNEEDEEALQFLTKVEVQEFEDIKSGYKINFYFDSNQYFENDVISKEFHLNSSK STPIKWKSGKDLTKKSRKRNMEEQESFFCWFTDHGDAGADELGEVIKDDIWPNPLQYYLA SEIEEDGG-EEGMMDEEKSLTKEEELLLQDFSRNVSTKSSALFYGNALIVSAIPIWLFWR IHQMDLYILFAVGTLVSTYLVAFAYKNVKFVLKHKIAQKREDAVTREMTKKFSDDKKMTR KERDERILWKKNEVADYEATTFSIFYNNAFYLVLLILCSFYVLKNFSPMFNYLMSVGLAA GLLALFSTSNK----KSKQIKLVLLGESGVGKSSIALRFVRGEFNENGEATIGAAYLTKT INVQNSTIKFDIWDTAGQERYHSLAPMYYRGAPAAVVVYDITSQVSFKEAQRWTREIIDF GGSCSYIILLGNKSDLRAVPYEDGKEFASNNGLMFTEVSAKTGMNVDDVFTNLAAKIAAQ SSP------------ASIFGTEKDKVNCSFYFKIGACRHGERCSRLHNKPTFSQTVLIEN LYMNPQNTALIQMDDTELQQFYDEFFEEVYVELE-KYGEIEEMNVCDNLGDHLVGNVYVK FRYEEDAEKAVNELNNRWFNGRPVHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKP ISRELRRELYGRSRRSRSRSPPTRRSRSRSRRERRSRSRSRERRRMFLTRSEYDRGVNTF SPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVVLAVEKRVTSPLIEASSIEKVFEVDDHIA CAMSGLIADSRTLIDRARVEAQNHWFTYNAKMSVESVTQAVSNLALQFGDDDADPGAMSR PFGVALLFAGIDNKGPQLYHMDPSGTFIQYDAKAIGSGSEGAQQALQDTYHKSMTLKEAC KSALTILKQVMEEKLNSSNVEMGTVTKEKKYHMFSKQELEDVIKDIAMKTWEMSNNMENI SALDEVYRYDKKQQQDILTAKPWDKDXHYFKHIKVSALALLKMVMHARSGGNLEVMGLLL GKVDGNTMIVMDCFALPVEGTETRVNAQAQAYEYMAAYTDAAKQVKRLENAIGWYHSHPG YGCWLSGIDVSTQMLNQQFQEPFVAIVIDPVRTISAGKVNIGAFRTYPKGYKAPDEAQSE YQSIPLSKIEDFGVHCKNYYSLEMSYFKSALDRKLLESLWNKYWVNTLSSSSLITNADYT TGQV-------------------------------------------------------- ----GLPRRIIKETQRLLQEPVPGIQALPDESNARYFHVIVAGPAESPYEGGTFKLELFL PEEYPMSAPKVRFMTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPD DPLANDVAEQWKVNESQAIQTARAWTKLYAENETELLDYE-DDETETKDVKGTYVSIHSS GFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILSMDVLCQAKSGMGKTAVFVLATLQ QLEPVDGQVSVLVLAHTRELAFQISKEYERFSKYMNNVKIAVFFGGMSIKKDEDVLKKNC PHIIVGTPGRILALCKVLNLKNVKHFVLDECDKMLAALDMRRDVQEIFRNTPHEKQVMMF SATLSKEIRAVCKRFMQDPMEVYVDDDSKLTLHGLQQHYVKLKDNEKNRKLFELLDVLEF NQVIIFVKSVQRCMALAQLLVEQNFPAIAIHRAMTQEERLSRYQQFKDFQKRILVATNLF GRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDETDAKVPPTYGDLG KAAKDIFSKGYNYGEWKLEAKTKTDSGVEFTTTG-SHSDKGIISGSLETKYKYSDLGLTF KEKWNTSNVLFTEIAIEDQLVKGLKLEFNTSFAPQTGTKSGKIKTSYKMDYLNLGCDVDF VFAGPTINAAAVLGYKGWLGGYQMSFDKSKLTKNNFAVGYEASDFTMHTNVNDGAEYCGS IYHKIRKDLEGGVKLSWSS-AKSTALELGTKYKIDSDSSVSAKVDSNSRVGLGYTTKLRD GVKLTLSALVDGKNFNAGGHQLGLGLDFEA------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------MDEIDAIRRFSEGTSADREIQRTLMELLNQMDGFDALGQV KMIMATNRPDTLDPALLRPGRLDRKIEISLPNEQSRLEILKIHAQPIAKHGEIDWEAVVK LSDDFNGADLRNVCTEAGMFAIRAERDYVIEEDFMKAVRKVADNKKLETKLDYKPV-SEN LVSVLKKFYDEYMTSTSKRLKIVDAYLVYILLTGVIQFVYCALVGTFPFNSFLSGFISTV GSFVLAVCLRLQVNPQNKTDFVGISPERAFADFIFAHVILHLVVINFIGTFSNPSQLLPL ELVDKCIGSRIHIIMKNDKEIVGVLLGFDDYVNMVLEDVTEFESTPEGRRVTKLDQILLN GNNITMLVPGGEGPEVIDHYENPRNVGSMDKKDKNVGTGLVGAPACGDVMKLQIKVDDDG KIIDAKFKTFGCGSAIASSSLATEWVKGKKLDEAVKIKNTDIAKELCLPPVKLHCSMLAE DAIKAALQDYKLKNQMLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKES FDYLKTLASDVHVVRGDFDENLNYPEQKVVTVGQFRIGLCHGHQVVPWGDTESLALVQRQ LDVDILISGHTHKFEAFEHENKFYINPGSATGAYNALDSNVTPSFVILDIQQSTVVAYVY KLVQDDVKVERIEYKKMGKFMKPGKVVLVLSGRFAGRKAVIVKNHDDGTQDKPYGHALVA GIDRYPRKVTRKMGKKKMKDRSKLKAFLRVYNYNHLMPTRYSVVNLDKSAVNKDAFRDPA LKRKARRDVKAKFEERYKTGKNKWFFQKLRFERSFIMVKPDGVQRGLVGEIMKRFEQRGY KLVACKQMQASKAHLEKHYADLSSKGFFAGLVTYMASGPVVAMVWEGDVVKTGRKMLGAT NPLDSNPGTIRGDYCIDVGRNICHGSDSVESAKREIDLWFKPEEVMSYNACEAPWLYE-- -------PPKAAEKAVKAKKAVLRGVHSKRNKKFRPSVHFRRPKTLSLPRAPKYPKKSVS RVCKLDRFSIVKFPLTTESAMKKIEDNNTLVFIVDKRANKPQVKQAVKKLYDIDVAKVNT LVRPDGEKKAYVRLAPDYDALDVANKIGIIMAAKQRMRLANEKHSKNITTRGNVPKSLKP AEEKYAVGPWLLGLFIFVVCGSAVFQIIQSIRMXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMIRFI LIQNRAGKTRLAKWYMHFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIVYRRYAGL YFCICVDVSDNNLMYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYSVVDEMFLAGEIRE TSQTKVLKQLLMLSSLEEPTIFSKIVDKSIPADIIYEDEQCLAFRDVSPQTPVHFLVIPK SPIPGLSTDLQLLGHLLLTAKRVAERSNGYRLVINNGPDGAQSVYHLHIHVLGGRQMSWP PMGGIWSYFSGLFGSRERRILILGLDGAGKTTILYKLQVGEVVTTIPTIGFNVETVQYKN LKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSMDRERMGISKQELFSMLEEDELKKAV LVIFANKQDIEGAMTPSEVANALGLTSITTHKYQIFXTSA-------------------- -GLYFHIGETEKKCFIEEIPDETMVVGHYKVEMFDRNVNDYVPTVYGLGMHVEVTDPEDK TIMSRTYAADGRFTFTSHSAGEHVICLHSNSTAWFSSGQLRVHMDIQVGEHAVDYSQIQA KDKLSELQLRIRQLLDQVEQITKEQNYQRYREERFRQTSESTNQRVLWWSIAQTVILLIT GFWQMRHLKSFFEAKKLVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXRLYCKAVFTGYKRGLRNQHENTALLKIDGVGSKSETPFYYGKRCAYVYKA KRKTACPGHDKASRIRVIWGKITRSHGNSGAVRAKFRKNLPSTAMGKRIRVMLYMAKKTY DLLFKLLLIGDSGVGKTCLLFRFSDDAFNTTFISTIGIDFKIKTVELGGKKIKLQIWDTA GQERFHTITTSYYRGAMGIMLVYDITNPKTFENISKWLRNIDEHANEDVEKMILGNKCGM ENKRQVSKDR-------------------------------------MPQNEHIELHRKR HGYRLDYHERKRKKEGRKAHEMAEKAKKLRGIRAKLYNKKRHAEKVQMKKTIKMHEERKT KQKNNDEVPEGAVPAYLLDREGQSRAKVLSNMIKQKRKEKAGKWDVPLPKVRGMSEAEVF KVIKSGKTKRKGWKRMVTKVCYVGEGFTRKPPKFERFIRPMGLRFNKAHVTHPELKATFC LPIIGVKKNPTSTMYTSLGVITKGTIIEVNISELGLVTQAGKVIWGKYAQVTNNPENDGC INAVLLVMAARPLISVYGDKGETTKSNVTLPAVFRAPIRPDIVVFVHSQMRKNARQPYAV SEKAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTRTWRRWHRK INVNQKRYAICSAIAATGIPAVVMSKGHRIEEIPEVPLVVSDKVEEFKKTKEAVALLKRV KAWGDIQKVYNSKRFRAGKGKMRNRRRIQKRGPLVIYNSDNGICRAFRNIPGITLINVSR LNLLKIAPGGHVGRFCIWTESAFRKLDKIYGSWKKLAADKKDYNLPKPKMTNSDLSRLLK SDEIQSALRLPKRDNRRRVLKKNPLKNPRVMNHLNPYSKVMRKAAQRKASRQAKLDAKRG IKTEAAKKAAKAKKTA-GSGGQELATRTLQIQSKRFYLDVKQNRRGRFIKIAEVGAGGKK SRLLLAMSTAAEFRDYLTEFSEHYASLGPPNPDNLPEDGKLKSEQMVKENRRYYLDLKEN QRGRFLRVSPRGGPRSQIAIPAQGMIEFRDALTDLLDEFGTDDHEGQNELPESKYLRVEN KVFYFDVGSNRRGVYLRISEANYRTAVTIPERSWGRFRDMLCEFCD---------QMRAT INQKLVETGERDRLKDLLRTRLIECGWRDQLKQHCKEVVKQKGLEHITVDDLVAEITPKG RALVPDNVKKELLQRIRTFLAQQADMNIRCARPEDLMNMQHCNLLCLPENYQMKYYFYHG LSWPQLSYVAEDEEGKIVGYVLAKMEEDPEDSVPHGHITSLAVKRSHRRLGLAQKLMDQA SRGMIECFDAQYVSLHVRKSNRAALHLYKNTLKFSVSEIEPKYYADGEDAYAMRRNLGEF REK-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMAEQEEQKKEPDSKR -VHTYPLIRHSDMNDEMKTEAMELCVTACEKFSSNNENAARMIKETMDKKFGASWHAVVG EGYGFEITHEVKNLLYMFFGGNMAIIVWKCS----KFSAPRHGSKAFLPKKRSRRHRGKC KSFPKDDKSKPCHLTAFLGYKAGMTHIVREVDRPGSKSNKKEIVEAVTILETPPMMIVGV VGYIETPKGLRAFKTIFAEHLSEDCRRRFYKNWYRAKKKAYTKYSKKWQDEDGKKEIERD FAKMKKYCKVIRVIAHTQMKLLKKRQKKAHIMEVQVNGGTVNQKVDWAREKLEKAVPIEQ VFAQDENIDCIGVTRGRGFKGVTSRWHCKKLPRKTHKGLRKVACIGAWHPSRVQFSVARA GQKGYHHRTEINKKIYRIGKGIHTKDGKVIKNNGATDYDPADKTITPMGGFPHYGEVNQD FVMIKGCCMGSKKRVITLRKSLLATFRKKAMEKISLKFIDTSSKYGHGRFQTFEEKKNFL GPLKKDMQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLG LWDTAGQEDYDRLRPLSYPQTDVFLMCFSLISPASFENIRAKWYPEVNHHCPNAPTILVG TKLDLRDDKDTIEKLKEKKLSPITYPQGLALAKELGSVKYLECSALTQKGLKMVFDETIR AVLCPKPTKKTKKGCVLLFDPSNMKKKKKKKMPFELDGGTTSEKADDFGIKKKKKKKKAF DMNELEDNLPEPESALPLKKKKLASDRDYTYDELLTRVFDIIREKNPDMVAGEKKKSVMR PPQVLKVGTRKSSFANFSDICRLLHRQPKHVLAFLLAELGTSGSVDGNNQLIIKGKYSQK QIENVLRRYIKEYVTCHTCRSPDTLLQK-------------------------------- --------FDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGK DYSLHRLILGTHTSEEQNHLLIASVQLPNDNAQFDASHYDSEKGEFGGFGSVSGKIEIEI KINHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPELRLKGHQKE GYGLSWNPNLNGHLLSASDDHTICLGDINQNPKEHRVIEAHTIFTGHTSVVEDVAWHLLH ESLFGSVADDQKLMIWDTRSNNTTKASHIVDAHTAEVNCLSFNPYSEFILATGSADKTVA LWDLRNLKLKLHSFESHKDEIFQVQWSPHNETIL-------------------------- ------------------------------------------------------------ ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVPETLLKKRKRNEEKQKEKRKIIFRRAE KYIKEYRAKERDDIRMARQARKNGNFYVPDEPKLAFVMRIRGINGVHPKPRKVMQLFRLR QINNGVFVRLNKATIHMLRIAEPFIAWGYPNLKSVRELVYKRGYGKVGNQRIPLTDNALI EKHLGRFGIICMEDLIHEIYTVGPNFKYAANFLWPFKLNTPNGGWRRKYNHFNDGGDFGL REDSINPLLRRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMRKAHPPELKKYM EKKINLKLNGGRQIQGILRGFDPFMNLVVDECIEETKLGERNQIGMVVVRGNSIILLEAL DRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXMGIKYNMAIGLNKGHRTIGRKNRPTRRRGALTKHARFVRDLVR EITGFAPYERRMQELLRIQKDKRALKFAKRRLGSHIRAKRKREEMQAVLQKMRKAMVDEA TKRTLAQIPLLKTKAGPRDGELWVTRLKEEYQSLIKYVQNNKESDNDWFRLESNTEGTRW FGKCWYVHELLKYEFDVEFDIPITYPTTAIEIALPELDGKTAKMYRGGKICLTDHFKPLW ARNVPKFGIAHAMALGLGPWLAVEIPDLIQKGIVTHK-------FLDDVRRMNPRQLYYQ VLNFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFFRGDLLFLTNYREEPIRVGE IVVFKIEGRDIPIVHRVLKVHEKEDGKVKFLTKGDNNSVDDRGLYAPGQLWLEKKDVVGR ARGFVPYVGIVTILMNDYPKFKYAILACLGLFVLIHREMSTMNPEYDYLFKLLLIGDSGV GKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYR GAHGIIVVYDVTDQESFSNVKQWLQEIDRYASENVNKLLVGNKSDMETKKVVDYTTAKEY ADQLGIPFLETSAKNATNVEQAFMTMAAEIKNRMGPVISAPSVKINASNPVKQSGG-CCX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------ ------------------------------------------------------------ --------------YRGAMGFILMYDVTNEESFNAVMDWCTQIKTYSWDNAQVVLVGNKC DLEDERVVSTERGKQLADQIGLEFFETSAKENINVKAVFERLVDIICDKMSESLDQD--- -----------------MNTHKMAITRDYISQPRITYKTVSGVNGPLVILDDVKFPKFAE IVQLTLADGSSRMGQVLEVSGSKAVVQVFEGTSGIDAKHTLCEFTGDILRMPVSEDMLGR VFNGSGKPIDRGPPVLAEDYLDIQGQPINPWSRIYPEEMIQXGISAIDTMNSIARGQKXP IFSAAGLPHNEIAAQICRQGGLGKLPGKSVLDDHEDNFAIVFAAMGVNMEAARFFKQDFE ENGSMENVCLFLNLANDPTIERI------------------------------------- ------------------------------------------------------------ ------------------------------RLMKSAIGEGMTREDHSDVSNQLYACYAIG KDVQAMKAVVGEEAPTPDDLLYLEFLTKFEKNFISQGHYENRTIFESLDIGWQLLRIFPK QMLQRIPQSTLEKYYPRDA-GPGFVGIKFCKECNNMLYPKEDKENKLLLYACRNCDYQEE ATNPCIYVNKITHEVDELTQIIGDVIADPTLPRTEDHPCPKCAHKESVFFQSHSTKAEEG MRLYYVCTNPQCVHRWTEKPPYKVADISLADWGRKCIEIAENEMPGLMQMREMHGASKPL KGARIAGCLHMTTQTAVLIETLTALGAQVQWSSCNIFSTQDFAAAAIAKTGVPVYAWKGE TDEEYIWCIEQTLVFPDGQPLNMILDDGGDLTNLVHERYPQYLDGIKGLSEETTTGVHNL AKMMAAGKLKIPSINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGKVAMVAGYGDV GKGCAHALRAFGARVMITEIDPIIALQAAMEGFEVTTVDECIKKARIFVTATGCKSIIHG EMFEQMLEDSIVCNIGHFDCELDVAWLNDNCVKKEQIKPQVDRYTLKNGRHIILLAEGRL VNLGCAHGHPSFVMSNSFTNQVLAQIELWTKQGQYKLGVHLLPKKLDEAVAAAHLEHLGV KLTKLSDDQSGYLGIPKDGPFKPEIYRYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXX-SFSNVENLSPQIIRQVSKEIADLCNDPPEGIKIFPNEEDITDIQAQIEGPSG TPYAGGLFRMKLVLGKNFPSEPPKGFFTTKIFHPNVASNGEICVNTLKKDWKAELGIKHV LLTIKCLLIVPNPESALNEEAGKLLLEQYEDYSSRAKLYTEIHAKPMFRSLIETARNNPL AKPFTKSSDVSGTGMAAAEETSCEFGSNKYYALCGFGGILSCGITHTAVVPLDLVKCRIQ VNPEKYGGIVNGFRLTVQEGGMKELAKGWAPTAIGYSAQGLCKFGFYEVFKIVYGNAMGE ENAFLWRTSLYLVASASAEFFADIALCPMEAVKVRIQTQPGWSSTLREGFPRILKEEGIN GFYKGLVPLWARQIPYTMMKFSCFERTLEALYKYVVPKPRSECNKSEQLMVTFTAGYIAG VFCAIVSHPADTIVSKLNNAPGSNFVSAAKELGLKGMWKGLGPRIIMIG-----QWFIYD SVKVYFRLPRPPPPEMPESLXRKL-HWKIERVLAVSMLGVMPACLFVIMDTLLITVLLHG FWGVDGVLTDYLELTIAGLAGLIYFNYNDVGVCEAIKMVW---SEAPEEDAAELQFPKEF ENAETLLISEVQRKTQNESAEEEQELSEVFMKTLNYTSRFSKFKNRETISAIRSVLMQKK LHKFELAALANLCPDNAEEAKSLIPSLEGRFEDEELQQLLEDIKTKRSFQYTLQPHLSKQ DVKTLNIDRLTPLTAEVISRQATINIGTIGHVAHGKXTVVKAISGVQTVRFKNELVRNIT IKLGYANAKIYKCNNDSCPRPGCYRSCGSSKEDNFPCDRPGCGRFQVQRHVSFVDCPGHD ILMATMLNGAAVMDAALLLIAGNESCXQPQTSEHLASGDHETWKHILILQNK-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------MAELLLDSDIRIWVFLPIALITFFTGIIKHYV TILLSSEKKTELQQVTDSHVLIRSRILRENGKFITKQGFLMRKSFFNAENTGYFAKNPMT DPSMMTDMLKGNVTNVLPMIVIGGWINWAFSGFLTTKVPFPLTLRFKPMLQRGVELVSLD ASWVSSASWYFLNVFGLRSLYTLILGQDNSADQTKAMQEQMSGAGMMTPPDP-------- --------------------MFLWDWFAGILNYLGLYKKSGKLVFLGLDNAGKTTLLHML KDDRMAQHVPTLHPTSEELSMGGMRFTTFDLGGHQQARRVWKEYFPAVDGIVFLVDVCDR ERFAEAKAELDSLLTDEQVASAPVLVLGNKIDKAGAASEDEIRHWLGLHGQTTGKGTVPR NELRPMELFMCSVLKRQGYGEGFRWLAQYXHXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--- ------------------------------------------------------------ ------------------------------------------------------------ ---------KTFNIKNDFTPAEEEQVRKENEWCEEKXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSASAVYL LDSKGKVLICRNYRGDIDMSVIDKFMSLLMEREEDMNTSPIIQHGNTTFIFIKYNSLYLV ATSKKNANVTMVFAFLHKLVQVFIEYFKELEEESIRDNFVLIYELLDEVMDFGFPQTTDS KILQEFITQEGHKMEVAPRPPPAVTNAVSWRSEKIKYRKNEVFLDVIESVNLLVSANGNV LRSEIVXAV--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --GRPPIHVKFEIPYFTVSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRTQMGILER IAEIDSEMSRTQKNKATSGHLGLLKARLAKLRRELIEPKGGGGGGGEGFDVAKTGDARIG FVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDG KGRGKQVIAVARTCSLIFIVLDVLEPLQHKKLIEHELEGFGIRLNQSPPNIGFRRKEKGG INLQTLVPQSELDIDLVKTILGEYKMHNADIVLRSDCTAEELIDVVEGNRVYIPCIYILN KIDQISIEELDIIYKVPHCVPISAHHKWNFDDLLEKMWEYLGLVRIYTKPKGQLPDYTSP VVVK-------------------------------------------------------- --------------------------------------------------------CVIC GGPGVSDAYYCKECTIMEKDRDGCPKIVNLGSAKTDLFYERKKYGFKKR----------- --KSEFRKIPIPSHRYTPLKENWMKIFTPIVEKLHLQIRFNLKTRNVEIKTCKDTKDIGS LQKAADFVRAFTLGFEVDDGLALVRLDDLFLESFDVTDVKPLKGDHLSRAIGRIAGKNGK TKFTIENVTKTRIVLADSKIHILGSFSNIKIARTAICNLILGSPPSKVYGNTRSVASRSA ERRIKVANPVVEMDGDEMTHIIWEKIKETLILPYVDVDLKYYDLGLPYRDQTDDQVTIDA ALATKKYNVAVKCATITPDEERVEEFKLKKMWLSPNGTIRNILGGTVFREPIICQKVPRL VPGWTRPIVIGRHAHGDQYKATDMVIPGNGKLELIYTPEGGQEQRTTVFDFKNGGGCSMX MYNTDESITAFAHTCFQYAIMKKWPLYMSTKNTILKRYDGRFKDIFEEVYQQGYKAKFDE LKIW-EHRLIDDMVAQALKSDGGFVWACKNYDGDVQSDVVAQGYGSLGLMTSVLVCPDGK TVESEAAHGTVTRHYGEHQKGNPTSTNPVASIYAWTRGLEHRGKLDGNNDLIAFSQKLEK ACVDTIDSGKMTKDLAGCIYGLKNVKPEHYLNTMDFLQAIRE---MGKLLSKIFGSKEMR ILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFSVWDVGGQDKIRPLWR HYYTGTQGLIFVVDSADRDRIDEARQELHRIINDREMRDAIILVFANKQDLPDSMKPHEI QEKLSLTRLRDRNWYVQPACATS-----------------FGDLKKKEGLSVLNAYLADK SYIEGFQPSQADAVVFDALSGPSADLENALRWYNHIKSYGAARSSFTGRKKDLSAYGPAG SDDDDDDDDIDLFGSKAE--RERRLAEYAAKKAPALIAKSSLLLDVKPWDDETDMAELEK CVRTIEADGLLWGASKLVPVGYGIRKLQINAVIEDEKISTDFLEDEITKFEDYVQSMDIA AFNKIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------LDMFIYQPLYLNAIQTTCSHILRYLTTAVITNKTVMKDLVKVI QQESXQYKDPITE----------------------------------------------- ------------------------------------------------------------ -----------------------------MGVEKQVLAQGDGKTFPEKGQTVVVHYTGTL TDGKKFDSSKDRGKPFEFKIGXSQVIKGWDEGVMTMSVGEKAILTCSPDYAYGPSGVGGV IPPNATLIFEVELLGLKMPKYYCDYCDTYLTHDSPSVRKTHCNGRKHKENVRLYYQKWLE EQVQKLVDDTTAAFKAAGKPGG---------PPQGPM-PMPGGP-MPLMGP-PGGPMGMM RP---PMGPMMPMMRGPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXLLLLVGVVLSDPTEFFREEFWRDRWVESTFKGADQ GKFAWTAGKFYGDADKDKGIQTSQDAKFYGISSKLEKPFSNEGKPLVIQFTVKHEQNIDC GGGYIKLYPKDLDQKKLHGDSPYFVMFGPDICGPGTKKVHVIF----------------- ------------------------------------------------------------ ------------------------------------EPPQIDNPEYKGEWKPKQIDNPDY KGKWVHPEIDNPEYTPDSNLYKYDDIGAVGFDLWQVKSGTIFDNILVTDDEKHAEEVGKA TWGATKDPEKKMKDEQDEEERKKREEEEKKRKEEEDKNDDEDDDXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNIFRLIGDMSHLLAIIILLIKM WKTRSVAGISGKSQILFALVFTTRYLDLFTSFVSIYNTCMKVFFISASYFTLFLMYHKFK ATYDSNHDTFRIEFLVVPVGGLAFLVNHEFAPLEILWTFSIYLESVAILPQLFMVSKTGE AETITSHYLFALGSYRGLYLLNWIYRYYFEGFFDLIAVVAGVVQTILYCDFFYLYITKVL KGKKISLPA--------------------------------------------------- ------------------------------------------------------------ --------------------------------------------HVVIGLKTAKGTKQLK LDPSIYESLQKEKVEVGDVIYIEANSGAVKRQGRSDSYATEFDLEAEEYVPLPKGDVHKK KEVIQDVTLHDLDIANARPQGGQDIMSMMGQLMKPKKTEITDKLRKEINKVVNKYIDQGI AELVPGVLFIDEGHMLDIECFT-------------------------------------- ------------------------------------------------------------ ---------------------------------------------EFEVDEEGDQGLLKL KEKAKKRKGRGFSTRSGVDDYEAMDVGGPGPQRSVEGWILFVT----------------- ------------------------------------------------------------ ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------- ----------------------------------TSKANVDYQDVIRSTIKQIGYDDSSK GFDYKTCNVLIALEQQSPDIAQGVHVDRDDDNIGAGDQGLMFGYATDETEECMPLTVVLS HQLNARIAQLRRSGELKWARPDTKTQVTIEYKYDKGACVPLRVHSVVISAQHDETVTLEK LRKELMEKVVNYVIPQKYLDSQTKYHIQPSGKFIIGGPQGDAGLTGRKIIVDTYGGWGAH GGGAFSGKDFSKVDRSAAYASRWVAKSLVKAGLCKRVLVQVSYAIGIAEPISITVFSYGT SKYSEKQLLEVINKNFDLRPGKIVKELNLRAPIYQKTACYGHFGRPDFPWEVPKKL--XX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMAKYTLVCVRHGESEWNQKNLFCGWHDADLSTTGVEEAKNAGKMSKEKGYQFDIAYT SLLKRAIKTLYMVQEELDLHWIPVIRHWRLNERHYGALQGLNKSETAAKYGEAQVKIWRR SYDTPPPALEPTDPRWSANDRRYGQFDASVVPACECLKDTVARVLPYWHDIIVPTIKSGQ RVVIXAHGNSLRALVKYL------------------------------------------ -------------MELQDEFYSNAEYIETASGNKVSRQSVLCGSQNIVINGKTIIMTDCV IRGDLANVRIGRHCVVSKRAVIRPPFKKFSKGVAFFPLHIGDHVFIGEDSIVNAAQVGNY VHIGKNCVIGRRCVLKDCCAIADDTVLPPETVVPPFTVFSGSPGMSFLFGGRSNKTFKPK KNIPEGTHQYDLMKHAAVTLGSGNLRQAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTIT EFCIEETCPVMSAGPKYEYHWADGQTVKKPIKCSAPKYIDYLMSWVQDQLDDENLFPSKI GVPFPKNFLSIAKTILKRLFRVYAHIYHQHFKEVVQLSEEAHLNTSFKHFIYFVQEFNLI ERRELAPLQE---------MGIDICHKNKRKVVRKEPRSQDIYLRLLVKLYRFLARRTNA KFNKIILKRLFMSKTNRPPLSVARLVRLMKRTGRDNKTAVVVGTVTDDLRLLDVPKLKLC ALNVTERARARILKSGGQIITFDQLALKSPKGQNTVLMQGPRKSRKAFRHFGRAPGVPHS STAPYVRSKGRKFEKGRGRRASRGYK-DLKHGSIEGSYNVARTVSLLRIVIAQSKCTTAK DVMESVVKEGKQLIAAQQSETAVGNMVRRVLKIIREEYVLDAINELIIELENSAQALEHI HANEVIRTVEAFLKKKFQVMVVEYHGQALAMSLARANIETTVINDSAVFAIMSRVNKVII GTHTVMAN---------------------------------------------------- -------------------------------------MIIPVRCFTCGKVIGNKWEAYLG LLQVEYTEGDALDALGLKRYCCRRMLLSHVDLIEKLLNYAPLEKRSPDPVEGRKHIDVQT ELYLEELSDRVEEADVEVQTDAFLDRPPSTMYVPAKTG---------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------KARGDLKEYQVVGRMMPRPRDRV PALYQMKIFAPDKCTAKSRFWYFVSQLKKMKKTQGEILQCKEMYEKHPLVIKNVGIWLRY VSRSGIHNMYREYRDLTSAGAVTQCYRDMGARHRARASTIQIIRVEEVAASKTRRPNIKQ FHNSKIRFPLTHRLNRKLHKPRFTTSRPHLTF-AYKEMEEFWDKNRNRPLSPLRIYNPEL TSMLSLCHRATGIAMAVTVPFVAATLLGLPGDFSSYIEYIKDLHLNPAILTAAKYVLAFP ICYHYINGIRHLAWDWAIGFDLKTTYQSGYFV---------SVALSAYRDQHFKGSRTEQ EKALLTSSTLYVGNLSYYTTEEQIHELFGKCGDIKRIVMGLDKVKKTPCGFCFVEYYTRE EGEYAMRYVNGTRLDDRIIRTDWDHGFKEGRQYGRGKSGGQVRDEYRTDYDEGRGGYGKI IATKI------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------CIFANFSVTGG KWIVSGSEDNLVYIWNLQTKEVVQKLQGHTDVVLCCACHPTENIIASAALENDKTIKLWK SDVMIVFQDLITGDELFTDAFKDFFYEVEGKGNVDIGGNPSSGCNIVLADKKSYQVYLKD YMKALKAYDFYLGVALLDYITPYMLFFKDGIKEEK-MAVEYDGGVVIGADSRTTTGAYIA NRVTDKLTKITDKIYCCRSGSAADTQAVADIVSYHLNFQKMDMGEEPKVKIAANIFRELC YNNRDNLSAGIIVGGWDKTEGGQVYAIPLGGMLTRMPFTTGGSGSTYIYGYVDANFKTGM TKEECLKF------------------------------------------XXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMVLADLGRKITSALR SLSNATIINEEVLNAMLKEVCAALLEADVNIKLVKQLRENVKSAIDLEEMASGLNKRRMI QHAVFKELVKLVDPGVKAWTPTKGKNNVIMFVGLQGSGKTTTCSKLAYYYQRKGWKTCLI CADTFRAGAFDQLKQNATKARIPFYG---------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------MSILEYNGAAIIAMKGRDCVAIASDRRLGIQAQTVSTNFQKIFEMGPRLYI GLPGLATDVQTVHQRLQFRLNLYELRENRRIKPKTFLSMVSNLLYERRFGPYFVEPVIAG LDPKTFEPFIASMDLIGCPMVTDDFVVSGTCSEQMYGMCESVWEPNMDPQELFESISQAL LNAVDRDAVSGWGGIVHIIEKDQVXTTELK----MTSKDYYFDSYGHFGIHEEMLKDEVR TLTYRNSMIYNKHLFRGKVVLDVGCGTGILSMFAAKAGAAKVIGIECSSIIEYGQKIVAE NNYSNVVTLVKGKVEEVELPDGIDKVNIIISEWMGYCLFYESMLQTVIYARDKWLKPGGL IFPDRATLYVAAIEDRQYKDDKINFWDNVYGFDMSAITKVAISEPLVDVVDPKQVVTTSC LVKEVDILHST------------------------------------------------- ---------------------------------------------------------MVK EDKSTWKSNYFLKISSLLDEYPKAFIVNADNVGSKQMQQIRQALRVLMGKNTMMRKAIRG HIEKNPLLEKLLPFIKKNVGLVFLKGDLVETRDLLLANKVKAPAKAGALAPLDVHVPAQA TTLGPEKTSFFQALQIPTKITRGCIEILNEVHLIKAGEKVGSSESTLLNMLGVSPFSYGL AVEKVYDSGTIFEPEILDITDDDLKAKFLMGVRNIAAISLTIGYPTAASAPHSIANGFKR LLAIAVETDYTFPAAEKTKESAVKGKLIAVIGDEDTCTGFLLGGIGELNKKREPNFLVVD KNTSRHDIEEAFRGFLKRDDIAIILINQTIAEEIRYVIDSHDQPIPAVLEIPSKDSPYDS SKDSILRRAKGMFSAEDMRGNENSLPMELCSNFDADEIKRLGKRFKKLDLDNSGSLSVDE FMTLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVRGDKLSKLRFAFKIYDMD KDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIIHADTDGDGKISFEEFCAVVGNMDV HKKMVVDVMTYLTSWEEFAKAAERLYLNDPQKCRFVTKYRHCDGKLNVKVTDDHVCLQYR TEHAQDVKKLEKLTNQLMRHMASKELYEEVKLSKSAREREKYDNMAELYAVINTLQSLEK AYIKDAVQPREYTGACSKLLVQYKAAFKLVQG-DFSTVEQFMKKYRLDCSAALERIKEDR PITIKDSQGNTSKAIADIVSLFITVMDTLRLEIRAMDKLQPDLKELMETMNRLSILPRDF EGTQKVKKWLDIFDEMSASEELDDNQVRQILFDLDSAYNAFNRILHDXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXARLVKKTIGGDKNGGHR LVRKTRMSRYYPTEDKPRKLRSAFSKHKHSLRSSITPGTVLILVAGRHKGKRVVFLKQLD SGLLLVTGPFHLNGCPLRRINQIYTIATKTKLDISGVKLPERLNDKYFNRKQLKKPRHTE GEIFDTKKEVYTVSDERKEDQVAVDKQILDVIRKNKEKKLLFGYLGSMFSLGSRQYPHKM VF---------------------------------------------------------- --------------VKKFILMRANIQAVSLKIQTLKSNNAMAQAMKGVTKAMMTMNRQLK LPQIQKIMMEFEKQSEIMDMKEEMMSDAIDDAMGDEDDEEESDAVVSQVLDELGLQLTDQ LSDIPNAGTSDKQQPQGVSDADADLEARLENLRRQ--YCDFCLGDSEENKKSNQPEELVS CNDCGRSGHPTCLQFTANMIISVKKYPWQCIECKSCGLCGTSDNDDQLLFCDDCDRGYHM YCL-----------------------TLDRPINLYPLTNYTFGTKEPLYEKDSSVPARFQ RMRDEFEKIGMRRSVEGVLIVHEHGLPHVLLLQLGTTFFKLPGGELNSGEDQVEGLKRLL TETLGRQDGGTMEWVVEDTIGNWWRPNFEPPQYPYIPAHITKPKEHKRLFLVQLPEKALF AVPRNYKLVAAPLFELYDNSAGYGPIISSLPQALS------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------YIGEMGKDYIYAVAP LLEDALMDRDLVHRQTSMSAIQHIALGVYGFGCEDALTHLLNYVWPNIFETSPHVVQAFM DSIEGMRVGIGPSKILQYALQGLFHPARKVRDVYWKVYNTV------------------- -------------DECMYDDEEYDLEYSEESNSEPDVDLENQYYNSKALKEDDPRSALES FQKVLELEGKDKGEWGFKALKQMIKINFKLGNFPEMMKRYKQLLTYIKSAVTRNYSEKSI NSILDYISTSKQMELLQNFYETTLDALKEAKNERLWFKTNTKLGKLYFDRGDYQKLQKIL KQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKTLYEQSLHIKSAIPHPL IMGVIRECGGKMHLREGEYEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGIN PFDSQETKPYKNDPEILAMTNLVSSYQNNDINEFEKILKTNRRNIMEDPFIREHIEDLLR NIRTQVLIKPIKPYTRIHIPFISKELNIDPTEVENLLVSCILDSAINGRIDQVNQVLELD TGTARYNAMDKWTAQL------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXX--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --TIKAFIPAIDSFGFETDLRTHTQGQAFCLSVFHHWQIVPGDPXDKSILIRPLEAQPAT HLAREFMIKSRRRKGLSEDVSINKFFDDPMLLELAKQDVMQSYPMQETFNLFDQRGDGKI AAAQLGDVLRALGQNPTEIEVKKCNNPDARISFEVFIPILQTISKNRDHATFDDFVEGLK MFDKDQNGFITSAELRHILTSLGDRLSDEDVDQLFQGMEDSQGNINYEEFIKMVMNGMPE MTFNVDHGYLEGLLRGFKSGILRQNDYLNLVQCETLEDLKLHLQSTDYGNFLANEPSPLT VSVIDDKLKEKLVVEFQHLRNQCVEPLSTFLDYITYSYMIDNIILLITGILHQRPINELI PKCHPLGSFEKMEAIHIASTPAELYNAVLVDTPIAPYFLDCISEQDLDEMNIEIIRNTLY KAYLEDFHSFCREMGGATAEAMCEALAFEADRRAFIITINSFGTELTKEDRAKLYPXCGD LYPYGLQLLAKADDYDQVRQVADIYGHYKELFEGSGTGPGEKTLEDKFFEQEVNFMKNSF MQQFQFGVFYAYVKLKEQENRNIIWIAECVAQRHRAKIDSYIPIF--------------- ------------------------------------------------------------ ----------------------------------------------------------RD IRTPCVLPDRKLTGHRQEVCGLKWSPDHQHLASGGNDNKLYVWNMTSTNPVQTYNEHLAA VKAIAWSPHQHGLLASGGGTADRCIRFWNTLTCQPLQCVDTGSQVCNLAWSKHSNELVST HGYSQNQILVWKYPSLVQIAKLTGHTYRVLYLAMSPDGGAIVTGAGDETLRFWNVFSKTR STKESKSVLNLFTRIRAILTIAFYYILTGKGTRIDFGWFLEQTSPYMWASFGVAITISFS VVGAAWGIFTTGASILGGGVKAPRIKTKNLISIIFCEAVAIYGIIMAIIIGQGDSYDAGF RMFAAGVTVGVSNVACGITVGIVGSGAALADAQ--------------------------- -----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGKLLGPKGVAVDKNGHIIVIDNKGS CIFIFQSNGKLISKFGSRGDWQFAGPHYVAINANNDIIVSDFHNHCIKVFDEGNFLFTFG SNGEGNGQFNAPTGVAVDQKGNILVADWGNSRIQVFDSSGSFLSFVNLYGP--------- ------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXX--EPKKVVNPLLEKRPRNFGIGQDIQPKRDLSRFVRWPKY IRLQRQRAVLMQRLKVPPPINQFSQTLDKQTATQLFRLMDKYKPESKQQKKARLKARAEE RAAGKEDKPTKRPPVMRSGVNTVTALVEQKKAQLVVISHDVDPIEIVIFLPALCRKMGVP YCIVLGRVVHRKTATCLAFTNVNSEDKNALNKLCEAVKTNFNDRFDEIRRHWGGGQMGNK SQARINKLEKAKARELAQKMRYVAAYLLAALSGNNSPSADDLKKIIGSVGIDCEADKITK IIGELKGKNLEELITKGQEKLASVPSGGPAAAAEAKKEEESDDDMGFGLFD--------- ---------------STEKGLFRAAVPSGASTGIYEALEMRDKG-KDYHGKGVLNAVNNV NNSIAGLVKMDEADQTAVDNKMISEDGTENKSKFGANAILGVSLAVCKAGAAKKGVPLYR HIADLAGNKEVILPVPSFNVINGGSHAGNKLAMQEFMILPTGASSFTEAMKMGTEVYHHL KAVIKKKYGQGACNVGDEGGFAPNIQDNNEGLQLLSTAIENAGYTGKIKIGMDVAASEFC KLYDLDFKNDKSKKEDWLPSDKLXDLYKKFIENYPIVSIEDPFDQ-----------IQIV GDDLLVTNPKRVQKGIDVKACNCLLLKVNQIGSVTESIQAWKMSKENNWGVMVSHRSGET EDTFIADLVVGLCTGQIKTGAPCRSERLAK-------------------------GAPPA AGAFVKKDAPPTAFRKFYERGDFPIALEHDTKGNKIAWKVEIEKLDYHHYLPLFFDGLCE TAHPYEFFARQGVHDMLEHGGSKILPVIPQLIIPIKNALNMRNPQVMCTTLKVLQHLVVS ADMVGEALVPYYRQILPILNIFKNRNLNSGDGIDYSQQKRENIGDLIQETLEAFERXGGE DAFNNIKYMIPTYESCMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXX---------------------------------------------- ------------------------------------------------------------ -----------------------------------------QYKDLQKYFLDDFDRLEXK DYMPTEQDILRTRVKTPGLVGVHFFLKNFNFKLFDVGVXRSERKXWIHCFEDVTAIXFCV AMSEYDQVLHEDETPIEMQESLKLFDSICNNKWFTDTSEEKIKKSSLTICFPEYTGNQTY EEAAAYIQAQFEAKNKSSTKEIYCHQTCATDTNNIQFVFDAVTDVIIANNLRGCGL-YHS KFTEPPKLVGNMALMPLRTTYKGPAFDIIDEAIYYFKANIFFRNYEIKSEADRTLIYITL YITECLKKLQKCSTKSAGSKEMYTLGLINFPIPGEPKFPLNAMFTKPANRAEEDTMRNYL LQIRQETGLRMVEKVFE-QDDKPSKWWLCFAKRKFMEKSLSSPG-AGPYNYSYIFKYIII GDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVT RSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIFLIGNKSDLEAQRDVTYE EAKQFADENGLMFLECSAKTGDNVEDAFLDTAKKIYQNIQDGSLDLNAAESGVQHKPATP RNPINTDQAPIDKGCAC----AVCVLKDSNVTGTVQFSQEAPVTLSGEIKGLTPGQHGFH VHQFGDNTNGCTSAGAHFNPFNKEHGAPEDTERHVGDLGNVTAGKISITDKMIDLAGPQS IIGRTVVIHADVDDLGKGGHELSKTTGNAGGRLACGVIGITKMVNFTVDQIREIMDRKHN IRNMSVIAHVDHGKSTLTDSLVSKAGIIASAKAGETRFTDTRKDEQERCITIKSTAISLY YELKKEDLRNAFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQA IGERIKPVLFMNKMDLALLTLQLEAEPLYQVFQRIIENVNVIIATYGIEDNPMGEISVDP KKGTVGFGAGLHGWAFTLKDFGAMYSKKFGIPEDKLMKKLWGDNFYN-DRGFVKYILTPI YHVFTTCMPKEKSLALAEKMGVKLTAEDKELEEKQLLKVIMRKWLPAGDAMLQMIVIHLP SPVTAQRYRMENLYEGPDDDVAAIAVKNCDPKGVLMMYISKMVPTTDKGRFYAFGRVFFG TVAPGLKARXMGPNYVPEKFIQRTILMMGRYIEPIEDVPCGNICGLVGVDQYLIKTGTIS TYKDAHNMRVMKFSVSPVVRVAVECKNPSELPKLVEGLKRLAKSDPMVQCTIEESGEHII AGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETVSEESDITCLSKSPNKHNRLFMKA RPMADGLPEAIDNGDITARQEMKERARILADKYGMDVGEARKIWCFGPEGTGPNILTDVT KGVQ-LNEIKDSVVAGFQWATKEGVLCEENVRGARFDIHDVTLHADAIHRGGGQIIPTAR RVLYACMLTAQPRLMEPIYLVEIQCPEQAVGGIFQCLNKRRGVVFDNQQIGSTPQFLVKA HLPVNESFGFTGDLRSCTGGQAFPQCVFDHWSILVVIDTRKRKGLKEGVPGLDNFLDKLX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- ------------------------------------------------------------ ---------------------MSVCGDRLVVGTAGRRILVWDLRNMGYVQQRRESSLKYQ TRCIRCFPNKQGYVLSSIEGRVAVEYLDPSPEVQXRKYAFKCHRIKENGVEKIYPVNAIA FHTHHNTFASGGS----------------------------------------------- --------------------MDFQHRAGGKTGVGGVASASESNRDRRERLRQLALETIDL NKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQANLARRAAKEAKEAPAQPAPE KARVDIKKFVKIGRPGYKVTKQRDPDNGQQSLLFQIDYPEIVEGIAPRHRFMAAYEQKVE PPDRKWQYLLFAAEPYETIAFK-------------------------------------- ------------MDDEQETYKLWRIRKTIMQLCHDRGYLVTQDELDQTLEEFKGQFGDKP SERKPSRSDLIVLVAHNDDPTDQMFVFFPEEPNVGIKTIKTYCQRMQEENITRAIIVVQN RMTPSAKQSLTDMAPKYILEQFLEAELLINITEHMLVPEHVVMTPEEKTELLSRYKLKES QLARIQ------------------------------------KDKESIGTVIGIDLGTTY SCVGVFKNGRVEIIANDQGNRITPSYVAFTADNERLIGDAAKNQLTSNPENTIFDVKRLI GRTWDDKSVQKDIQYYPFKVINKNGKPHISVEANGEEKVFAPEEVSAMVLGKMREIAEGF LGKKINNAVITVPAYFNDAQRQATKDAGXIAGLNVMRIINEPTAAAIAYGLDKKEGEKNI LVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKKGKDIRK DNRAVQKLRREVEKAKRALSSQHQAKIEIESLFDGEDFSETLTRARFEELNMDLFRSTMK PVKQVLEDADLKKEEIDEIVLVGGSTRIPKVQQLVKDFFNGKEPNRGVNPDEAVAYGAAV QAGVLSGEEDTGDLLLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQIFSTAADNQPT VTIQVFEGERPMTKDNHLLGKFDLTGIPPAPRGVPQIEVTFEIDVNGILKVTAEDKGTGT KNHIVIQNDNNRLSPEDIERMINDAEKFADDDKKVKEKVEAKNELESYAYSLKNQIGDKE KLGGKLSDEDKKTIEEAVDEKIKWMESNADAEVEDLKAQKKELEEIVQPIMTKLYQEAPP PSGADEKDELDSTADDPELEAIKARVREMEEETEKLKEMQKEVDTQMSAEEKMDADARSV YVGNVDYGATAEELEQHFHGCGSVNRVTILCDKFTGHPKGFAYVEFADKDSVTTAQALDE SLFRGXQIR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------EELEKKVDFWMEKYEKDVEAKQHELDVLKASKA KDLDKLQELTKLYKEYEQVVVEDRIEKEKARRKADQEAIELRAAIRVQSWWRGVMVRKGF GPYSKKKKGKLKVGINGFGRIGRLVLRAALDKVDVVAVNDPFIDLDYMVYMFKYDSTHGV FNGEIKLVINGKAMSVYCERDPANIPWSKDGAEYIVDSTGCFTTLDKAGSHMKGGAKKVI ISAPSADAPMFVCGVNAEKYSKDQNIVSNASCTTNCLAPLAKVIHEKFGIVEGLMTTVHA YTATQKVVDGPSNKDWRGGRGAAQNIIPSSTGAAKAVGKVIPDLNGKLTGMAFRVPVPDV SVVDLTCRINKGASYNDIKAAIKNELKGILGYTEDDVVSQDFRGDKRSSIFDAKAGIALN DNFVKLVSW--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------SNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQ RAHVIVMAATNRPNSVDGALRRFGRFDREVDIGIPDATGRLEILRIHTKNMKLADDVDLE QVAQETHGHVGADLAALCSEAALQQIREKMDLIDLEDEHIDAEVLDSLAVTMEDFRWALS KSNPSALRETCVEVPTVTWEDIGGLESVKKELQELVQYPVEHPEKFLKFGMTPSKGVLFY GPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFD ELDSIAKARGGNAGDGGGAADRVINQLLTEMDGMGAKKNVFIIGATNRPDIIDPAILRPG RLDQLIYIPLPDDKSRIAILKANLRKSPVAKDVDVNYLAKVTHGFSGADLTEICQRACKL AIRQSIEAEIRMERERDKDPEDFDPVPEISRAHFEESMKFARRSVSDNDIRKYEMFAQTL QQSRGFGG---------------------------------------------------- ------------------------HTGPVLDVDWSDDGTKVFTASCDKTAKMWDLQSNQA IQIAQHEAPVKTIHWIKAPNYTCVMTGSWDKTLKFWDTRTPNPIDTIQLPERCYCADVKY PMAVVGTAGRELIIYQLENRPQEFTRIESPLKFQHRVVSIFLDKKNNAPTGFALGSIEGR VAIHYVNPTNPKDNFTFKCHRSGVQDIYAVNDIAFHPVHGTLATVGSDCKFSFWDKDART KLKTSEAFDQPLTSCCFNPQGNVFCYATSYDWSKGHEGFDPXK-KPHIFLRSCFDELKPS MKKMSSPSPGKRRMDTDVVKLIESKHEVTILGGLNEFIVKFHGPQGTPYEGGVWKVRVDL PEKYPFKSPSIGFMNRIYHPNIDEVSGTVCLDVINQAWTAIYDLANIFEAFLPQLLTYPN PIDPLNGDAAAMYLHKPEDYKKKVLEYVKKYATEEALREHESSMSDFSEDEAQDMELMGD TEVLTTLKILIIGESSVGKSSLLLRFTDDTFDPEQAATIGVDFKVKTLQVDGNRAKLAIW DTAGQERFRTLTPSYYRGAQGAILVYDVTNRASFQKLDVWLNELETFSTKHDLIKMLVGN KIDQENREVSKEDGLKFARKHHMLFIEASAKTREGVQCAFEELVEKIIQTPGLWETSGID ISQVIWSIINGTFCSFKVRTKSQKFCRNEYNLTGLCNRASCPLANSQYATVREEKGVCYL YMKTVERAAFPSRMWEKVKLSRSYEKALQQINEHLIYWPKFIKHECKQRFTKITQYLIRI RRLVLKRRKKLVPLSRKIEKRERRKEEKALIAAKIDTAIEKELLERLKSGTYGEXYNFPS HAFDK----------------------------------LMQTRCPEPARMKKFAVYRWD PEKPGDKPKMQTYDVDLNTCGPMVLDALIKIKNEMDPTLTFRRSCREGICGSCSMNIGGS NTLACLCKIDDNLGKATKIYPLPHMYVIKDLVPDMSNFYAQYRSIEPYLKKKDGSDKNIG DKQYLQTTGDRAKLDGLYECILCACCSTSCPSYWWNSDKYLGPAVLMQAYRWMVDSRDDY TSERLFQMEDRFSVYRCHTIMNCTKTCPKGLNPGLAIGEIKKMLAKYNS------DARPN QTIYINNLNEKVKKDELKKSLYAIFSQFGQILDIVAMKTLKMRGQAFVIFKDINSANSAL RSMQGFPFYEKPMRIQYSKKDSDIIAKMKGTFVERPKRPKEHESKKKKKANAPTAIPEQP PNQILFLTNLPEETNEMTLSMLFNQFPGF------------------------------- -----------------MDSQGRKVVVCDNGTGFVKCGYAGSNFPAHIFPSLVGRPIIRS TAKIGNIEIKDIMLGDEASELRSMLEVNYPMENGIVRNWDDMLLLYDYTFGPEKLNLNCR DSKILLTEPPMNPNKNREKMIEVMFEKYGFQGVYIAIQAVLTLYAQGLLTGVVVDSGDGV THICPVYEGFALPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMMKEKLCYV GYDIEQEEKLALETTVLVESYTLPDGRVIRVGGERFGAPEALFQPHLINVDGVGVAELLF NTIQAADIDTRPEFYKHIVLSGGSTMYPGLPSRLEREIKQLYLERVLKGDTTKLSKFKIR IEDPPRRKHMVFLGGAVLADIMKDKDSFWMTRQEYEEKGLRVLDKL--------GKVITC QAAVAWEAKKPLTLETVEVEPPRAGEIRIKVLYTGVCHTDAYLLDGFDPEGAFPIIMGHE GGGVVESVGEGVTSVQPGDHVIPLYIPQCNECKFCKSPKTNLCGKIRATQGKGVMPDGTS RFKCKGKTLLHFMGCSTFSQYTVVTEISVTKVNPAAPLDKVCLLGCGISTGYGAALNTAK VEPGSTCAIWGLGAVGLAXAMGCKEAGAKRIIGVDINPDKFELGKKFGLTEGVNSKDYNK PIQEVLVGXDXGGLDYTFECIXNXACXXTALXSCXKGWG--------------------- -----------------------------------------------------------X XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXDPNKITKVVVHPLVLLSVVDHFNRMGKVGNAKRVVGVLLGSNRQG ILDVSKSFAVPFDEDDKDKTVWFLDHDYLESMYSMFKKVNARERIVGWYHTGPKLHQNDV AINELLRKYCPNSVLVVIDAKPKDLGLPTEAYIAVEEVHDDGTPTTKTFDHVPSEIGAEE AEEVGVEHLLRDIKDTTVGSLSQRITNQLMGLKGLHAHVNDINSYLQKVTSKQLPVNHQI VYQLQDVFNLLPDVNLQDFVKSVYVKT--------------------------------- --------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXX-----KRVVLNDLSQLPQDYSTTPGGSIFSTTPGGTKIFYDRHFLLKCRNSPLT KSPPANMAKIPGITTP---GKRKEIYKYEAPWTVYSMNWSIRPDKRFRLALGSFVEEYNN KVQIVSLDEETSEFTSKSTFDHPYPTTKIMWIPDAKGGYPDLLATSGDYLRVWRVSRLEC LLNNNKNSDFCAPLTSFDWNEVDPNLLGTSSIDTTCTIWGLETGQVLGVVSGHVKT---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------PVIGGHSGVTIILL FSQATPAVSFPREERKKLPERIQNAGTEVVEVKAGAGSATLSMAFAAARFAYKMLDPLNG ADNKVECAYVRSTETPAAYFVTPLLLGKNGVEKNLGIPKTIEYEAQLIENAMPELQSNFK KGIEFMSK---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------EPTRENV QGMRQAVYEKLDEDGIISPGIRVSGDDVLIGKTLTLPANEDELEGTTKRFTKRDASVFMR RSETGIIDQVMITLNQEGYKFCKIRVRTVKTPQIGDKFASRHGQKGTCGITYRQEDMPFT CEGITPDIIINPHAVPSRMTIGHLIECLQGKVAANKGEIGDATPFNDAVNVQKVSNLLHQ YGYHQRGNEVLFNGFTGRKLNAQIFLGPTYYQRLKHMVDDKIHSRARGPLQILNRQPMEG RARDGGLRFGEMERDCQIAHGAAQFLRERLFEASDPY----------------------- ------------------------------------LLAETPGGFSFENCCRNXVFXKGI KAPTAYKTGTTIVGLVYKDGVVLGADTRATEDTVVADKNCSKIHYISDNIYCCGAGTAAD TEMTTQMISSQLELHRLNTGRTPRVCTANRLLKQMLFRYQGHISAALVLGGVDSTGPHLY SAYPHGSTDKLPYVTMGSGSLAAMAVFERGFKPNMEKEEAKKLVRDAIAAGIFNDLGSGS NVDVCVITKKVNYIRPFDEANLKGQRQGSYRYKKG-----------------MSKVTFKI ILTSDPKLPYKVLSVPEQTPFTAVLKFAAEEFKVPPATSAIITNDGIGINPAQSAGNVFL KHGSELRLIPRDRVG-MAFTFAAFCYILALILTAVLIFFAIFHIIAFDELKTDYKNPIDQ CGSLNPLVLPEYFIHILFTFLFITAMEWFTVLLNIPLIIYHIRRYINRPVMSGPGLYDPT TIMNADELNRAQKEGWIKLAFYLISFYYYLYCMIYTLVS-MGLLTILKKMKQKEKEVRLL ML---------------------------------------------------------- ------------------------------------------------------------ --------------------------------------------HNKKKICYYYDGDIGN YYYGQGHPMKPHRIRMTHNLILNYGLYRKMEIYRPHKATQEEMTKFHSDDYIKFLRSIRP DNMSDYNKQMQRFNVGEDCPVFDGMYEFCQLSTGGSVAGAVKLNKQAADIAINWAGGLHH AKKSEASGFCYVNDIVLAILELLKYHQRVLYVDIDIHHGDG------------------- ------------------------------------------------------------ ----------------------------------LLLGGGGYTIRNVARCWTYETSIALG VEIANELPYNDYFEYYGPDFKLHISPSNMANQNTGEYMDKIKTRLFENLRMLPHAPGVQM TAIPEDALNDEENPDERISIRASDKRVTGEGEYSDSEDEG---------------GRAFF ECNICLDTAKDAVVSMCGHLFCWPCLHQWLEARPNRQTCPVCKAGISKDKVIPIYGRGAS EQTDPREKLPPRPQGQRSEPENNRGFPGFAFGFQMSFVIEAFPFGIFASTLNFNDGRPGP APPGTAHHNEEQFLSKVFLWVAVLFIFWLLIALYSIIFKQENAHEDSIWSCAWQQSDRDR SENIITGGIDDLVKVWKWTGLELRHVLEGHQLGVVSVDMNLSGTLAASSSLDSHVRVWDV DTGKCIKSMEAGPVDAWTISFSPDSRFLATGSHSGKINLFGVESGRKEESLDIRGGFTLS IAYSPDGKLIASGAIDGIINIFDTQTGRLLEGHAKPIRSLCFSPGLQLXVTGS------- ------------------------------------------------------------ -------------------------------------------NYAQFDGWELRQLINFV AADDGVPEPEIIIEVLKGCRNNNDYALATRFLEVVRLKGGNKMSETWPYIMQEIGPTMQE LGISTLKEMGYEEPELWLENVDDMCIRLRNIPGGAQVTDILTFLGEFSQFIIFQGVHMVY TAQGEPSGEAFIQMDSEESAQLAINRNKRPIKKRIIDVIQCSGEDMNLVLTNDGRFPDVC SSCGGGPATCLLSPDCLL------------------------------------------ ---------------------------------------------------VTPENIQIQ ILPGRLTGDALISFMTRSEAERAITRGKQTMGQCLIELF--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GIFNPGKILTVLFGGSTKFVFEGADRS IHDALCVIRCLVKKRALIAGGGAPETELSLQLNDYANTLTGMEQYCFRAFAEALEVIPIT LAENAGLNPIATVTELRNRHAQGEKTAGINVRKGAITNILEENVVQPLLVSTSAIHLATE TVKSIMKIDDIVNC-MILLEINNRIVEETLTLKFQNAEAGNKPDNVDITVADFDGVLYHI SNPNDEKSKIRVSISLKFYKDLQEHGADELIKKEYGDYLAAPEAGYNVSVVFDEKVPKDW EDWVTKVGLLKRNCFASVFEKYFQFQEEHKRAVIQYRDDETMYVDAQKDRVTVIFSTIFK DDDDVVIGKVFMQEFKEGRRKFQQAPQVLFSHRDPPQELANTGARGGDNIGYITFVLFPR HAARENTINLIHTLRDYLHYHIKCSKAYIHSRMRAKTSDFLKVLNRARPEVKDKEKKTIM LTFCPTCANVLVVEEGQNCYRFACNTCPYVQNIQRKIASRKYPKLKEVDDVLGGAAAWEN VDSTEETCPKCSHNRAFFMQIQTRSADEPMTTFYKCCNMACAHRWRXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------NEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRDN Q-SPDLQWLIIRNNSSFLLKGNTYSREQNNLKSKNSFRYNGLVNRQTVGVVPAKDGKGVV LVTKKAGKRPGSSYNKVELKRGSRQTFSTIRKTLRNNSYRKDLKMAAVRRASALLKSQKP VVVKK--DEPYYCSQQINIPPSLPDILKQFTKAAIRTQPKDVLAWSAAYFKDMAKGETPP VKERLEMPTATQKTDTGLTPGLLRVLNKQLGPKKTVSLNLVMEKWADLALPKEQFDDLVR IGSFGGEVEWNKFFALCASALGENITDAMKTVCEILTADPEGGPSRIPFPLFKDLYTYLA QIDGEISQQQINEVCNYLKYHVDKQDGYVQPRNFPEAECP----KLDPAKRDEFMNEVKQ QLAIASAQELLQKMTNKCFKKCITKPGTSLSNSEHKCVAMCMDRYIDTQNLVAQAFSSRL QQEMSRMMNRLFGRGKEKQPPPNLTDCVNSIDSRGESIDKKIGRLDAELKKYKDQMKKMR DGPSKNMVKQKAMRILKQKKMYENQRDNLMQQSFNIEQQNYAIQSLKDTKTTVDAMKIGA KEFKKAYKHVNIDSIENLQDDLEDLTEQANEIQEVMGRSYGMPEVDDDELEAELDALGDD LALDEDSSYLDD-VALPSVATSEPGGESMKEGN-VPVDEFGLPQIP-----MTPATPASP QLQNIVCTVNLGCKLDLKKIALHARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTG AKSEDQAKLAARKYARIVQKLGFAAKFLDFKIQNMVXSCDVKFPIRLKGLVL-------- -------------------------------------------------------ISEED DDFVEMGLEAEPSTKRDAEDFPYEVLPADQIVQFMVDCIKEVNAVVQIPSTVTRILLNHF KWDKEKLMERYYDGDQDRLFTEAHVICPHRRLDETMCEICCVPVPADMTGLECGHKFCAP CWTDYLTSKIVNEGMGQTISCAAYGCDILVDDATVMSLVTDKKVKLKYQQLITNSFVECN RLLRCCPAPDCGHAVKVQYFDTKPVTCKCGHTFCFACGENWHDPVQCKWLRKWIKKCDDD SETSNWIAANTKECPKCHVTIEKDGGCNHMVCQNCKADFCWVCLGPWEPHGSSWYNCNRY DEDEAKKARDNPEKSRSALSRYLFY----------------------------------- ------------------------------------------------------------ --------------------------------------------XXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMDPKKLKDLLA--QGGKKGGRLGMGLMAL AGAAI-GIQQSFYTVDGGHRSIIFSRIGGVQKQVLAEGLHFRVPWFQYPIIYDIRARPRK ITSPTGSKDLQMVNISLRVLTRPDQTFLPQIYRQIGTDYDERVLPSICNEVLKSVVAKFN ASQLITQRQQVSMLIRRELTERAQDFHIILDDVSITELSFGKEYTAAVEAKQVAQQEAQR AQFYVERAKQEKQQKIVQADGEAQAAKLIGEAIQQNPGFLKLRKIQAAQKIAKTLATSQN RVYLQSGNLMLNITDKDFDSNLE------------------------------------- --------------------------------INSCTHITAQTAVLVETLAALGASVRWA ACNIYSTQNEVAAALAEAGFSIYAWKGETEEDFWWCIDKCINSEGWQPNMILDDGGDATH LMLKRYPAMFNMIKGIVEESVTGVHRLYQLSKSGKLTVPAMNVNDSVTKTKFDNL----- ------------------------------------------------------------ ------------------------------------------------------------ -------VDHIIWPDGKRIILLAEGRLVNLSCSSVPSFVVFITSATQALALIELYNAPQG RYKQDVYLLPKKMDEYVASLHLPTFDAHLTELTDEQAKYLGLNKTGPFKPNYYRYPDPDA IKMFVGQIPRSMDENDLRKMFEEFGAVYQLNVLRDKATGQSKGCCFVTFYTRKAALDAQN ALHNIKTMSGMHHPIQMKPADSEKRN-EERKLFVGMISKKCSESDVKMMFAPFGSIED-- ------------------------------------------------------------ ---------FVSGGVGGVCLVVAGHPLDTIKVRLQTMPPLYKGTFDCAMQTIRKEGFFGL YKGMSAPVMFAVCFLGFGV-GKKLQLAGVFTTAIMTPGERIKCLLQICAKQLYREGGIRS IYRGTAATLLRDVPASGMYFMTYEWLQHVLTPKGHDRNELSVRTLTAGGFAGMFNWLVAI PPDVLKSRLQ-------------------------------------------------- ------------------------------------------------------------ -AEQSKWRMQRDRLTDDFSTALKNFQTIQRTAAEKERASVEDVDLDMLHEREAAIKQLES DITDVNQIFKDLGMLVHEQGEMLDSIEANVETVHVEEG---------------------- -------------------MVNVDKGILVECDPAMKQFLLQLDDTKALGRKFVIKDLDDT HLFISADILETLQDQVDGLMDKLSFPLGKNKDKAPSPQEGIQRLREVEEMLMKKSDFLEK KIEQELTTAKKRAALAALKRKKRFEKQLQQIDGTLTTIEFQREALENASTNTEVLKVMGV AAKALKGAHNNLDVDKVHDLMDEVAEQQEIANEISDAISNPVGFGQDQDEDDLLAELEEL EQEEIDEQLIGVPTLPSVPTDE----------IS-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ SELQLPFQACLKVEKFGDLILKATEPQMVLFNLYDDWLKTISSYTAFSRLILILRALHVN NDRTKVVLKPDKTTITEAHHIWPSLSDEEWMKIENQLKDLIMADYGKKNNVNVASLTQSE IRDIILGMEISAPSAQRVQIAEIEKQTKEQSQLTATTTRTVNKHGDEIITSTTSNYETST FASKTEWRVRAISATNLHLRTNHIYVSSDDIKETGYTYILPKNVLKKFIIISDLRAQIAG YLYGVSPPDNPQVKEIRCIVLPPQWGTHQTVHLPNILPNHEYLKEMEPLGWIHTQPNELP QLSPQDITTHARVMADNPSWDGEKTVIITCSFTPGSCSLTAYKLTPTGCEWGRQNTDTGN NPKGYLPSHYERVQMLLSDRFLGFFMTPSESSWNYNFMGVRHDPNMKYELQLSNPXEFYH EIHRPSHFLNFSSM------------YTTTRKNLMIDKNTKVICQGFTGKQGTIHSQQAI EYGTRMVGGVSPGKGGQVHLGLPVFNSVQEARDKTNCDASVIYVPPPFAAAAIVEAIDAE IPLVVCITEGIPQQDMVKVKHKLVRQNKTRLIGPNCPGIIKPGECKIGIMPGHIHQRGRI GIVSRSGTLTYEAVHQTTMTGLGQTLCVG------------------------------- -----------------NGPTAKPVVSFIAGLTAPPGRRMGHAGAIIAGG---------- ----------------------------ASAESLKCTICQERLEDTHFVQCPSVGDHKFC FPCSRNSIKMQGAGTEVYCPSGKKCPLVGSSVPWAFMQGEIATILG--RFVEVGRVAYIS YGPDAGKLAVIVDVIDQNRALVDGPCSGVSRKQMNFKALELTSIVMIPRGLRPGNLRKAW EKQEVQKKWDSTTWAQKIANKKKRAQLTDFDRFKLMKAKQARNRLINVEFGKLRKTVKKT CPLLLRVFNNIGRHNAMSEYHRGQTPANELQIYTWLDATLKELTSLVKEVNPEARRKGTF FDFAIVYPDPRAPVYRLREIGTTCAGHKGQDDGVSLANKKFVIGDFLDIAITPPR----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------QWIEPPKRERKANYAVDAYFREALRV SEPKAPKAPRPPKQPNVQDFQFFPPRLFELLDKEIYYFRKSISYRAPKNPDLGADAERVR KEEQGKIDEAEVLTEEELAEKEDLLKGFTNWSKRDFNQFIKANEKYGRDDLDSIARDVEG KTPEEVMEYSGVFWDRCNELTDIEKIMAQIERGEGQIQRRISIKKALDAKMARYRAPF-- ------------------------------------------------------------ -------------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------------- ------------------------------------------------------------ ----------------------------------------------------ASRFAQEN ELMFLETSALTGENVEETFLKCARSILTKIESGELDPERMGSGIQYGDTSIRRMSSKRPD CACLLKPSSVEQLDTSQWPLLLKNFDKLNVRTAHYTPIPAGYSPLKRPIQEYLKSGFINL DKPANPSSHEVVSWVKRILRVQKTGHSGTLDPKVTGCLIVCIERATRLVKSQQGAGKEYV CIFKLHSAVEDEKLVAQKIEMMTGALFQRPPLISAVKRQLRIRTIYECKMWEYNKEDAMG IFWVSCEAGTYIRTMCVHLGLFLGVGGQMQELRRVRSGIMSEKSQLYTMHDVMDAQWTYD HHKDESYLRRVVNPLEALLTSHKRIIMKDTAVNAVCYGAKIMLPGVLRYEDGIEVNDEIV IVTTKGEAVALAIAHMTTAVMATCDHG--------------------------------- ------------------------------------------------MATADWDRKKQP KASQLRSQQAINSAQRQGLSVETTKKYDGGHNRQLKGDKNTAKLDRETEELHHDTVGMDV SKLIQYGRNQKKLSQKDLATKINEKTQIVTEYENGKAIPNQQVLAKMERILGIKLRGKDK GQPM---MLKPKALTQVLSQANTGGVQSTLLLNNEGALLAYSGYGDKDAAVTAAIASNVW MSYQKSGTVAFSDDKLKYIMLECEEGKVAITKVANLLLCICSKENVGFGMLKAKMEALAL YLEEPLSQVAAS--ATSRIPPKKQTLEDAYSPPANFLEIDITDPQSKGRYTDYAVKMKTN LPVFKVKESTVRRRYSDFEWLRNELERDSKIVVPPLPGKAWKRQLPFRSDEGIFDDDFIE DRRKGLEQFINRVAGHPLAQNEKCLHMFLQETNIDKNYVPGKIRTT-------------- -------YGIGQTFINKTFGYRGVIFGQNPATLH---ITEPFGGRKKEKKHKYYHVLCDE RDTRRNDVSIQRVYAASDVTNKFLVHVRGVDLVPHEDVLPYQSTENPIIGNKLFAKW--- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------SKGANTYNRPNWEDAEFPILCQTCLG DNPYIRMMKEKYGKECKICARPFTVFRWCPGARMRFKKTEVCQTCSKLKNVCQTCLLDLE YGLPVQVRDAALKVQDNMPKSDVNKEYYTQNMEREIATNDGTAPGGALGKAMAPSDMLLK LARTTPYYKRNRPHICSFWVKGECKRGEECPYRHEKPTDPDDPLADQNIKDRFYGSNDPV ADKLLQRYTDMPKLTLPED-DVFLMIRRKKTTIFTDAKESTPVSDVKKIVEGILKIRPED QKLFKDNKTLGDYGFTFATARAQAPATIGLACKEFEQLEITPLSSPPELPDVMKQQDSTS AHAQE---RLGRVELRRLINSHKDEDFVKATELLERGEQQVFNNNH------NFSPGGTC YDRYQYFPDYTIDYWHPLEKAQYPKYFATREIRKMEHILWWHEKYG---MEDYIKIEKIG EGTYGVVYKGRNKKSGRLVALKKIRLESEEEGVPSTAIREISLLKELQHPNIVCLEDVLM QENKLYLVFEFLSMDLKRYMDTIPNGQFMDKMLVKSYLYQIMQAILFCHQRRVLHRDLKP QNLLIDNKGVIKLADFGLARAFGIPVRVYTHEVVTLWYRAPEILLGSQRYSTPVDIWSVG CIFAEMMTKRPLFHGDSEIDQLFRIFRTLTTPTDETWPGVTSLPDYKPTFPNWKTNQLAS AVDNTGLDLLQQMLIYDPANRISAKKALSHIYF----FTKLGTLGVAVAGLGSVVNLALY NVEGGHRAVLFDRFRGVQEKVSGEGTHFLVPWVQRPIIFDCRSRPRNVSVITGSKDLQNV NITLRILFRPVVNELPKIYTNLGLDYDDRVLPSITNEVLKAVVAQFDASEMITQREIVSQ KVSEELITRASQFGIILDDISLTHLTFGRKFTLAVEMKQVS------------------- ------------------------------------------------------------ ---MKELHTSQTVKIPKGVSASVKARKVIIKGPRGTLTRTFRHLAVDITMVGKNTVMVEK WFGKHKELAAVRTVCSHIENMIKGVTKGFLYKMRSVYAHFPINCAVQEGGCSVEIRNFLG EKFVRKVGMLPGVSIKPS-TQKDEFILEGNDIEAVSTSAALIQQSTTVKNKDIRKFLDGI YVSEKTTVV--MGCAVSADDKAAVERSKQIDKALRVDGEKASREVKLLLLGAGESGKSTI VKQMKIIHEKGYSQEECLQYKPVVXSNTIQSMIRHHPSHGTIKLEFGYPERADDARKLFS VTGNAEEGDLSPELAAIMKRLWKDSGVQGCFSRSREYQLNDSAEYYLYSLDRISQPSYXP TEQDXLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTXIIFIGAMSE YDL--------------------------------------------------------- ------------------------KAIYPHFTTATDTSNIQVVFQVVMDSILRDNLR--- -----------------------------KKPNPENITERNLPQASSAMFFKYNTQLGPP YHIIVDTNFINFSIKNKLEIIQSMMDCLYAKCIPYITDCVMGELEKLGSKYRVALKIARD PRFKRLPCLHKGTYADDCIVQRITQHKCYIVATCDKDLRRRIRKIPGVPIMYLQQHRYSI ERMPDAFGAPK------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------KDVTSLDWNCEGTLLATGSYDGYARIWSTEGRLVNTLGQHKGPIFA LKWNKRGNYILSAGVDKTTIIWDASSGNCTQQFAFHSAPALDVDWQSNATFASCSTDQCI HVCRLGMERPMKTFQGHTNEVNAIKWDPQGQLLASCSDDMTLKIWSMRQDPCVHDLQAHS KEIYTIKWSPTGPGTNNPNVPLILSSASFDSTVRLWEVEQGRCLHTLTKHQEPVYSVAFS PDGKYLASGSFDKCVHIWNVQSGQLVHSYRGTGGIFEVCWNH------------------ ---SNSDLASLFECPVCFDYALPPITQCQSGHIVCQPCKQKLNICPTCRGPLGNIRNLAM EKVATTVMFPCKYSSSGCPVTLLHTDKQEHEETCEYRPYCCPCPGASCKWQGSLEQVMGH LMQQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHNFMLVLEKQEKLEGQQMFYA IVQLIGTRKQAENFAYRLELNGHRRRLSWEXTPRSIHDGVQS------------------ --------------------FQQEYMEMPPITRAYTTAXVLTTIAVQLDIISPLQIYLDP TAVFSKYQVWRLVTNFTYLGSIGFNFLFNIIFAYRYCRMLEEGSFRNKTADFFFMILFGC TLLTVTVNLVFLGSALTIMLVYLWSRRNPYVRMNFFGLMTFHAPYLPWVLLGFSVLLGNS VITDLLGIAAGHIYYFLEDVFPQQPGGFKILKTPRFLTYLFEGAPEDPKLHPLPPGGFNW GEGLELLSDQGFRIDGRRSHELRKIQCKLGVFSQADGSAYVEQGNTKVLAAVYGPHEIRG SRSKQDKVLVNCQYSMATFSTSERKRRPRGDRKSQEMTMHLQQTFNAAILTSLHPRSQID IFVEVLQSDGGNYCASVNAATLAVIDAGIPMKDYVCACSASYLGDSPIVDINYLEESSGP EITVAVLPKSEQIVFLEMNGRLHEDNLSKVVDMAVKGCKDVYGVLDRTVREMPGNYHFVI VGHLDNPIFEMEFCPPNRAAEPKKDDHRHLNQFVAHEALDLVDEQVWTTNNMYLKIVDKF NEWFVSAFVTASRMRFMMLHDVKNEDGIKNFFTETYEMYIKHSMNPFYEINKPIVSPAFE KKVQLYGRKYL-------HTDIPEPDFEAYRSNSSKAKRKVYSYTLVGGASAATVYMGKE IVQDLVGYLDINDAARALAITEIKLNDVPVGKSLLTTWKGMPLFVRHRTEAEIKAEQAVD LLSLRDPQHDSDRSLTPEWMILVGVCTHLGCIPLQDQGSFGGMYCPCHGSHYDSSGRIRK GPAPLNLTV--------------MSRQGTRGVDLRKVNGELFSLTYGALVAQLLKDYEDD EEVNKQLEKMGYNIGVRLIEDFLARSNVGRCNDFRETADVISKLAFKMYLGIQPVVSNWS AAGDEFSLLIENNPLTDFVELPPGHSQLNFSNILCGVLKAALEMVQMEVDVRFVQDTLXG DNITEIRLKFVKRLEDAVP------IKEFLAKAKEEFQNKWDHPGQNTSCLDDFDRIKTL GTGSFGRVMLVQHKANKDFYAMKILDKQKVVKLKQVEHTLNEKKILQAIQFPFLVSLDFH FKDNSNLYMVLEFVTGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKP ENLLIDSQGYLKVTDFGFARK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------RVWDVHTGEMLNTL IHHCEAVLHLRFCDGIMVTCSKDRSIAVWDMQSPTEINLRRVLVGHRAAVNVVDFDEKYI VSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDCLVVSGSSDNTIRLWDIESGACL RTLEGHEELVRCIRFDNKRIVSGAYDGKIKV-DLAAALDPRSPAGSLCLRT--------- -------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXITRSAQPLVGRRNRQDEHYIQT IMDANAQSHKLYIMDARPLVNALANMVRGGGYEREEWYTNAEIAFLDIHNIHVMKDSLRK LREVVFPTIDDSKWLSNIEATHWLDHIKQILAGALRVADKVESAKTSVLVHCSDGWDRTA QLTSLASLMLDPYYRTIKGFEVLIEKE-LSFGHKFAQRVGHGEDRHSDTDRSPVFLQFMD CVWQMTQQFPNAFEFNEHFLITIIDNAYSCLFGTFLCNCDQQRTEKGLKQKTVSLWSFVN CQVEEFTNPLYQHVLFPVASLRRIELWTGYYCRWNPRMRPQEPIHLRNKELLILKAQLQK KVDELLKE-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---- -----------------------------SVDGFIGDINSGHWDTVLQAIQTLKLPDNKL IDLYEQIVLELIELRELGAARSLLRQTDPMIMLKHNQNDRFLHLENMLARSYFDPREAYP EGQTKEKRRNAIAQALAGEVNVVPPSRLLALLGQSLKWQQHQGLLPPGTTIDVFRGKAAV KEQEEEKYPTQLSKTIKFGQKAHIECARFSPDGQFLVTGSVDGFVEVWNFTTGKIRKDLR YQAQDNFMMMDEAVLCMCFSKDSEMLATGAQDGKIKVWKILTGQCLRKFDKAHNKGITSV NFSKDNSQLLSASFD--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------YFKTELAPPIEAKESI AKFLDLPFMSGQKIANMNVKEASLLVADVAVFFVVGEVIGRRCWGGYKIPGA-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------TQVFXDRVFQECFTYEGEM------------------------------- ------------------------------------------------------------ ---------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXX------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------QWADLIICKTRRLSLFHQGMKNHHMTFGLFFETALAAFLTYCPGLEQG LRMQNLRWSRWFPAFPFSIAIFIYDESRKYILRRNPGGFVERETYYSFNNSPKGFKMLGL IVVGGIGTYIAVKELMLHPPKYPWWHRGWFTEIDKKSARRGYMVYKQVCSACHSLNRVRF REMIGIIFTEAEAKAEAAEYQIIDGYDENNMPIKRPGKLFDAIPSPYDNQIQAENANNGV APPDLSYVVLGREGGEDYIFSLLTGYYEPPAGVKLPEGVHYNPYFPGGLIAMAQALYDEI IEYEDGTPATQSQLAKDVTTFLTWAGEPYYDSKKALEFKAYILLLFVGSYYFYRRTWSSL KHKLVVWQRPDLPSKCTYYEAKMKESPHIHKELKPKIMPNVLYNIGNTPLVKVNRITQEE SIPCDVYAKCEFFNAGGSVKDRIGLRMIEDAEAAGMLKPGDVLIEPTSGNTGIGIALGAA VKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTSAAFDSPESHIGVAKRL--------- ---------------------------------------------------------VIG VDPLGSIIAEPEDVTFYEVEGVGYDFIPTVCDRKLVDKWYKSDDKESFIMARRMIRQEGL LCGGSSGSAMANALKAIKDFGMKTGQKCVVILPDSIRNYMTKFLSDDWMSQRNFXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMP DIMRLITKDLSEPYSIYTYRYFIHNWPKLCFLAMDKEKCVGAIVCKLDMHKKMVRRGYIA MLAVDADYRRKQI----------------------------------------------- ------------------------------------------------------------ --------------------------------------MPGGGQSPDREVSLDMKHGVEA KSYDELAKAEKLKPLEVELRRLEDLSKSIVDDFEYMKSREKMMRDTNESTHSRVMYFSIF SMCCLLGLATWQVFYLRRFFKAKKLIEEMESGRTSSVGNDILGF---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------DILVLHHPTTISVRYQAMVHVGSVRQTATIMNMTKEHLRTGDKSIVRFRF IKNPEYLKTDMRMVFREGRTKAIGNITKLYPHVSANTRQQRAAKKAQEXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXGDVFMEKHWKSVIHKSICDYFFEEQGKAGSPEDVPPVIATPHH YLLNIYRNQLYFVAVVTTEVPPLFVIEFLHRIFDTFEDYFTECSETTLKEHFVIVYELLD EMLDNGFPLAVESNILKELIRPPNFLRTITDTVTGKNTGVSATLPTGQLSNVPWRRTGVK YTNNEAYFDVIEEIDAIIDKQGNTVIAEVQGYIDCLIKLSGMPDLTLSFINPRLLDDISF HPCVRYKRWESEKVLSFVPPDGNFRLISYHIGAKNMVAVPLYIRHNIQYREGSGGRFEVT IGPKQTMGKVVENISLGVPF---------------------------------------- ------------------------------------------------------------ ----MATALRPNTRYQPPDWFTNNYTISTNAERQRDASHQVRQESRFLRNETDNQTKWDQ HSNNVRLADRVDNIRQWKEILEKTLADIDKEIADLSDAKELTEQALEAKNLPMDVAIECL TLREGRQGIDV------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------TNLKKVLTVKI PEKQQEVIAFRKEHGKTKVGEVTVDMMYGGMRGIRGLVTETSVLDPDEGIRFRGYSIPEC QKLLPTAKGGKEPLPEGLFWLLVTGDVPTQQQVEAITREWNERSPLPNHVITMLNNFPHN LHPMTQFSAAITVLNSESKFAKAYSEGVNKLKYWEYVYEDSMDLIARLPTIAAIIYRNLY RAGTSVGVVDMDKDWSYNFTSMLGYDEPDFTELMRLYLTIHSDHEGGNVSAHTTHLIGSA LSDPYISFAGGMNGLAGPLHGLANQEVLVWLTQVQVSDEKLRDFVWNTLQSGKVVP--GH AVLRKTDPRYMCQREFALQKLPNDPMFRLVSQLYKIVPDVLLEQGKAKNPWXNVDAHSGV LLQHYKMTEMNYYTVLFGVSRALGCMASLIWDRALGLPIERPKSFDTPSLRKLASMPPKF GGGEKCGICSKSVYAAERIEAGGTPFHKLCFKCSECKMSLKLNTYAQADGILYCKKHYQE IVVAKNTQ-SQSFVHRDSPENNPNTPFEFTQENIKRADVIIGNYPEGHQAAAVIPLLDLA QRQHGWLPISAMHKVAEMLDMPKMRVYEVATFYTMFNRKPVGKYFVQICTTTPCILGGVG SDVILKAIEENLGIKPGEMTQDGMFSLLEVECLGACVNAPMVQINDDYFEDLTVDDINKI LNEIKQGKKPTPGPQSGQNRRFASEPKGGLTSLSEPPTGPGFGVRPDLMENFRKIEKIGE GTYGVVYKAQDKTTGQLVALKKIRLDTESEGVPSTAIREISLLKELDQSCIVRLLDVVHS EQKLYLVFEYLNQDLKKYMDSCASGMPSSLIRSYMHHLLLGIAYCHSHRVLHRDLKPQNL LID--------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------XXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXMPYQYPALTPEQKKELSDIAHRIVAPGKGILAADEST GSIAKRLQSIGTENTEENRRFYRQLLLTAVNPCIGGVILFHETLYQKADDGRPFPQVIKS KGGVVGIKVDKGVVPLAGTNGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPS ALAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDH HIYLEGTLLKPNMVTPGHACTQKFSHEEIAMATVTALRRTVPPAVTGITFLSGGQREEEA SINLNAINKKPWALTFSYGRALQASALKAWGGNNENLKA--------------------- ------------------YIQSLPKSVKRRIKALKKWQFEAAKIEADFYKEVHELECKYA SKYTPLYEKRKTVITGNVEPTDEECDWPSDDEKEDEKANVEEGEDVKGIPHFWLTVFKNV DMLSEMVQEHDEPILQHLQDVQVKFSMGFTLEFYFDTNDFFTNTVLTKHYSMRSEPDEED PFSFEGPEIVKCKGCEIDWKKGKNVTVKTIKK------------XAKTVQNDSFFNFFNP PQVPDDDMDEDLEALLAADFEIGHFIRERIVPRAVLYFTGEALEEEEND------IILLK EGTDSSQGVPQIVSNINACQSVADAVRTTLGPRGMDKLIINDQGKSIISNDGATILKNLD IVHPAAKTLVDIAKSQDAEVGDGTTSVVLLAGEFLKQSKPFIEENVHPQIVIRAFRKATD LAVQRIKEISVKVKKDKGEHRELLEKCAATTLSSKLVAHQKDFFAKMVVDAVMHLDELLP FDMIGVKKVTGGALEDS------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------LRDYSRTIAGKEQLM ISAMAKALEIIPRQLCDNAGFDATNILNKLRQSHAALWSGVNIMKEDICDNFEGFVWEPA VVKINAITAASEATCLILSVDETIKNPKSGGDPGGPGMGRGR--KRNNVIPNGHFHKDWQ RYVRNWFNQPARKQRRHDNRVKKARRIAPRPVAGSLRPIVRCPTFKYNTKIRAGKGFTLD ELKAAGINKKLALTIGIAVDYRRKNKSLESQQQNTQRLKEYKSKLILFPKKQSKPKKGDA TEEEIKMATQLTGLVMPIKKAYKPEKARKITDAEKKFSAFTALRQARAAKRLQGFREKKA RE-MPNIKVFSGMSHPDLAQKICDRLGIEPGKVVTKKFSNGECCVEIGESVRGEDVYIVQ SGCDEVNDMLMELLIMINACKIASACRVTAVIPCFPYARQDKKDKSPISAKLVANMLSVA GADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWVKDTIPDWRNSCIVSPDAGGAKRVT SIADRLNVDFALIHKERKKANEVATMVLVGDVKDRIAILVDDMADTCGTFCHAAEKLTEA ------------------------------------------------------------ -------------------LTCRFYKNKYPEVEDVVMVNVRSIAEMGAYVHLLEYNNIEG MILLSELSRRRIRSINKLIRIGRNECVVVIRVDKDKGYIDLSKRRVSPEEVTKCEEKFAK AKAVNSILRHVGELMKFHSDEQMEELYTKTAWFFDDKYKKPGASYEAFKHAVTNPEILDE LDIDEETKSVLLQNIKRRLTPQAVKIRADIXVCC-------------------------- ----------------------MARGQQKIQSQQKNAEKAAKLKHDQKKAAQAALTYKCT VCMSQMPDPKTYKQHFESKHPKSPLPDCLKD-MLGNLHEDMKSQGVTTKTKGVCGACNQP VIGQVITALGKVWHIEHFTCANCNLPLGTKNFYERGGEAYCEEDYHKIFAPKCAYCNGPI VDKCVTALDLTWHPDHFFCAQCGRPFGDDGFHEKNGKAYCRQDFLDMFAPRCGGCGHPIL DNYISALSRHWHPECFVCRDCHQPFGGRSFFDHEGLPYCETHYHAKRGSLCASCQKPITG RCITAMGKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCHPCFVKLFMRPLTDEETKSFFD KLSKYIGENIKLLLERPDGSYCFRLHRDRIFYVREDLMKKAGNISRKNLLSMGTCFGKMT KTGKFHLQITALDFMAPYAKHKIWLKPSAEQQFVYGHHVMKSGLRRITENTSQYEGVVVY SMNDLPLGFGVAAKSTQDCRHADPMTLVAFHQADIGEYIXNEEAL---RKFFVGGNWKMN GNKQSIDGIADFLKTGDPNTEVVVSPPACYLGYTRQKVIGVAAQNCYKVSSGAFTGDISA DMIKDLGCEWVILGHSERRNVFGESDQLIGEKTKYALSKGMKVIACIGEKLEEREAGKTE EVVFRQTQADQWPNVVLAYEPVWAIGTGKTATPEQAQEVHEKLRAWLAERVSKEVAASVR IIYGGSVNAGNCXDLGAKPDIDGFLVGGASLKPDF------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------RCQKICDQWDRLGTLTA QRRQGLDEAEKILEKIDTLHLDFAKRAAPFNNWLDGAKEDLLDIFIVHSVEEIQQLLEAH ETFKQTLPEADKEFNAIMALASEVQRLANQVGLQ-LTDNPYTTVDPQDIANKWADVKHLV PKRDGTLQNEMMKQQNNMRLRKQFAAKANVVGPWIENQLDAVASMGIQKSSLEEQLKKLR QYEQATTQYKPNIDELERYNQEIQEAMIFENHYTQYTMETLRVGWEQLLTAIARNINEVE NQILTRDSKGISEDQMNEFRVSFNHFDKNRSRRLEPKEFKACLVSLGYNIRDDRQGDADF QRIMSIVDPNNSGYVTFEAFLDFMTRETADTDTAEQVMQSFKILAGDKPYITAQILRQEL PPDQAEYCIQRMAPYSGRDAVPGALDYMSFSTALYGESDLNKLAIDQIDVSGKRVLMRVD FNVPLKEGKITNNQRTVAAIPTIKYALEKGAKSVVLMSHLGRPDGRKADKYSLLPVKAEL DKLLGKPVEFLSDCVGAEVEAKCADPPAGSVFLLENLRFHLEEEGKGVNEAGEKVKASKE AVEAFRQSLSKLGDVYVNDAFGTAHRAHSSMVGCQLEQRASGFLLKKELSYF-------- ------------------------------------------------------------ ----------------------------------------------MGLDVGPQSIAKFA EVVGRAKTIVWNGPPGVFEFENFKKGTVALMDAVVAATQRGATTIIGGGDTATCAAKFGT EDKVSHVSTGGGASLELLEGKTLPGVAALSDA-SGVPPNTWQPSNVTIETTMGQLVLELY WKHAPNTCRNFAELARRGYYNNTKFHRIIKDFMIQGGDPTGTGRGGASIYGKEFDDEISN EL-HTGAGILSMTDSGPNTNGSQFFITLAPTQWLDGRHAIFGRVSSEMTVILRIGLVECD NDDRPVD----------------------------------------------------- ------------------------------------------------------------ ----------------------------------------------------VQDSPHKI FIGGLPNYLNEDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDQGCAGLNGMQLG DKKLI------------------------------------------------------- ------------------------------------------------------------ --------------FLPLFDRVLVERFAPELKTKGGIMLPEKSQGKILQATVVATGKGAR DQQGNIIPPSVKPGDEVLLPEYGGTKVVLEDKEYFLFRDSDILGKFERLKAQIPDIKTSL DIVKHLQSRKDPMETRFLLSDQVYAKARIPPTENVNLWLGANVMLEYGIEDAKVLLEKNA ANKSLSQVEDDLSFIRDQTTTLEVNMARVYNWDVKRRQ----MADEALARAGLHFDELNK IRVLEPDVAQQTVELKEECKEFVDKIGDFQKIVGSFIEVVDNVSKEVEKEKMKALGSRNL LKSIAKQREAQQQQLQALITERKMQLERLRIQYEALQKEENEQNEFIEQFTLQKXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX DDVADEISSSQFPLNIVRNRRGAVSAEVYKEEDAAQYVKKVVPKDYKTMAALSKAISRNV LFSHLDDNERSDIFDAMFPVHRHAGEVIIQQGDEGDNFYVIDQGEVDIFVNDEHVTTIGE GGSFGELALIYGTPRAATVKAKGDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLGKVSIL DNLDKWERLTVADALEPVQFE--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------VYLQNWSHVQSYVNKAESTPEMAEGKDGGQIVLTKLKCAAGL ADLATKKYKSAAKYFLQANFDYCDFPELLSPCNVATYGALCALASFDRQELQKNVISSSS FKLFLELEPQLRDIIHKFYESKYASCLKLLGEIKDNLLLHMYLAPHVNVLYTQIRNRALC QYFSPYLSADMTKMAEAFNTXVPALENEIMQLILDGQVNARIDSHNKILYAKDTDQRSST FEKSFAMGKEYQRRTKALILRSAMLRNQIHVKSPPRDGGQGGEMSIAPGTVSSXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXX------------------------------------- -------------------------------------SLPGFKTRHKNLDFVIIREQTEG EYSALEHETVPGVVESLKIITRKNSKRIAKFAFDYAMKHNRSKVTAVHKANIMKLGDGLF IKCCEEVAQFYPKIKFDTMIIDNCCMQLVSNPHQFDVMVMPNLYGNIVDNLAAGLVGGAG VVPGESYSSDVAXFEQGARHAFAEAIGKNIANPTATLLSACNMLKHIHLD---------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -AVTCFSFLSGDVNNFVVGSEDCTVYTACRHGGKTGISEAFEGRMGPITGIDCHNVPGQI DFSPYFLTSSFDWTLKLWSIKDQKFLHSFEDNSDYVYDVQWSPIHPALFASVDGDGRLDL WNLNNETEVPTAS---VCSRRGRWHSVDPSIAVGDDVGRIHIYXVXENTAKPKMDEWSRF VRTLQELKQ-------------------VVEQQLDAEIEKLDRMEDDDYEKLRQRRLDAM KNAQKQKQELMAKGHGKYYEIASEKDFFEESKRSKKLVCHFYRDSTFRCKIIDKHLEILA PKNVETKFVKINAEKCPFLVETPRIVVLPTLCIAIDGKTTDYIVGFDELGGVDDFPT--- ------------------------------------------------VVAIAEDPQPGD GEILIKNRYVGINASDINVTAGRYGSKIKPPFYIGFEGLGEV------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------------MS RKQTPSEFLKQIIGRPVVVKLNSGVDYRGVLACLDGYMNIALEQTEEYVNGQLKNKYGDA FIRGNNVLYISTQKRR-MAYEQSALLLRKQLADLNKNPVEGFSAGLIDDEDLYKWEVVII GPQDTPYEGGFFKAHLIFPKEYPHRPPKMVFKSEIWHPNIGPDGVVCISILHEPGDDKYG YETASERWLPVHTVETILVSVISMISDPNDESPANVDAAKMWREQPEDFKKRVARCVRKS QD-------PERKKQLEDFGQYVGQCLPRYVQKVRLMSGDELEILIHPEGVLPVMAFLKD HHNAQFTNIVDIACVDVPTRVFRFEVIYNLLSIRYNSRIRVLTYTDELTDLDSTCKLFPV SN-YETEIWDMSGVYF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------CVSLGVGPSVSDTEMGLGGTSQWKMCGLYPNTTLALFFEVVSQHNAPIPQGG RGYLQFITQYQHSSGQRRVRVTTLARNWADASTNIQHIAAGFDQEAAAVLMARTAVFRAE TDDGPDVLRWLDRMLIRLCQKFGDYQKDDPNSFRFSENFSLYPQFMFHLRRSQFLQVFNN SPDETSYYRHMLNVEDLTQSLIMIQPILYAYSFNGTPEPVLLDTSSIQPDRILLMDTFFQ IVLYHGETIAQWRKQGYQDQPEYENFKQLLNAPVDDAQEIL------------------- ----------------------------------------------------NEAQMKLF TDLEIEMTADMYNKMTACCLQKCIPPKYKEAELSKGEAVCLDRCVAKYMEIHDRIGKKLT QLSTEDEARVKQMQATQQPQVIHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYR KKVVLDGEEVQIDILDEYAAIRDNYFRSGEGFLCLFSITEQESFQATVDFREQILRVKND DTIPFLLVGNKADLEDKRYVSVEEAQERAKQWSVPYVETSAKTRANVDKVFYDLMRAIRD RKMEKKSKKRKCTIL--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------QLKTECGCQFTSKLEGMFKD MTVSNTIMEEFKTSLNQSVNMAGVDLVVRVLTTGFWPTPNANSRCNIPPSARTAFENFRK FYLNKHSGRMLTLQPQLGSADLNATFYGQKKDDAGGSKEPRKHIMQVSTYQMCILMLFNK SEKWTFEEIKNETDIQERDLIRAIQSLSVGKVSQRVLHKEPKTKEVEPAHVFTVNDHFTS KLF--------------------------------------------------------- ----------------------------------------DRINIFPSRMAMAIMKARLK GAQKGHSLLKKKADALTMRFRAILKKIIETKVLMGDVMKEASFSLAEAKFTSGDINHMVL QNVNKAQLKVRSKKDNVAGVLLPVFEGYQDGSDSYELTGLSRGGQQIDRLKKNYARAIQL LVELASLQTAFVTLDEVIKITNRRVNAIEHVIIPRIERTLAYITSELDEREREEFYRLKK IQEKKRKIK--------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------------FTALTRLDQ IRVQAQVAARSAVKNCVIWGNHSSTQYPDLTYAVVAREAIKDDXWVKNDFVKTVQQRGXX VIKARKLSSAMSAXKAIVDHVHDWWFGVPEGSMVSMAVPSDGYGIEEGLVYSFPVRTDHT YEIIKDLPIDDFSREKMDITMKELVDEKNMAMSACXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXMTTIRPFVCEDLFRFNNVNLDPLTETYGLPFYMQYLARWPEY FQTCESAGGRIMGYIMGKAEGGGEKWHGHVTALTVAPEFRRLGLAGKLMNNLEQISEQKK CFFVDLFVRVSNKVAVNMYRKLGYEVYRTVLEYYSGDVDEDAYDMRKALSRDKDKKSMIP LKRPVRPDEL-------------------------------------------------- ------------------------------------------------------------ ----SSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRSAHYKLTST VMLWLQTSKDASGVMNLGGSLTRQVEQDATVSDASPHIVNIGKMVEDMENKIRNTLNEIY FGKTRDIVYGLRSFIPLKQDALRNDLAAALSKRS-XXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXX---------------------------------- ------------------------------------------------------------ -------------TSMLTQSIPYKEGSKQLAWMLHSAVVGGIVAPLTMLGGPLLVRAAWY TAGVVGGLPALAMCAPSEKFLNMGGPLAIGLGVVFVSSLGSMFLPPTTSLGAGLYSISIY GGLVLFSMFLLYDTQKVIKRAENHPVYSAQKFDPINACMGIYMDTINIFIRIATILAGGG GRRKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXWAEKTKYLSPIS KPLASRKLTKRLYKVIKKAIVSGIKFVQKSIRKGDSGIMILAGDVSPIDVISHIPILCEE NQIPYCYVPSKTDLGGACGNRRSMTMLIVKPNEDYQDLFEECKTEIQNLPMPIMPIENLE EEGLEKNPNFEHAQRKFLLETDKYKNDVEIKKKLLAAVEANCMAPFYEELCKDLKWKCDE NLLKKMKAANEAELKKLDVSIEDAEKNLGETEVREFMLKKAEYLCKIGDKEASLTQFRKT QEKTVTLGYRLDLVFHLIRMGLYYMDHDLITRNLEKAQSLIDEGGDWDRRNRLKVYRGVY CMSIRDFKQAATLFLDTVATFTSYELMXYQTFVTYTAICSMI------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------SRGLKNPAEAPKGIPYNKLTIGVPKEIFKNERRVAMSP ATVTVLKKGFNINIEENAGLEAKFKNDEYAKAGAKISKKEAFESDIVLKVRAPMTEEIAN FRSGTTLISFLYPKQNPELVKQLAEQNLNVFAMDMIPRISRAXXFDALSXMANISGYKAV VEAANNFGRFFTGQITAAGKXXPAKVFVIGXXXAXLAFIGTAKALGA------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------EIDVPSAVEMITEARNIIITPGYGLCVAKAQYPI--------------- ------------------AEAGVPYDIVLEMDEINDDFPETDLVLVIGANDTVNSAAEED PNSVIAGMPVLRVWGSKNVIVMKRTLGVGYAAVDNPIFFKQNTSMLLGDAKKTCDALLTK IK--------GFPPGVEYLTQVDQFLFKQQIEFLEVFTGWETANKYKITNTQVQQVFFAA EESDACSRQCCGPNRSFTIHITDNMGQEVIRVVRDFKCGAGCPWCACLAHEVTIEAPPGQ VVGYVRQGWCPPKYSIRDAILRMEGPTCMITGPCCPNDIDFNIFGTEVGKISKQWSGMLR EMFTDADNFGVSFPMDLDVKIKAVMIGAVFLIDFMYFEQNQNXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-N RSSGLVQRKTATVEEEDHESKETRLTLMEEILLLGLKDREGYTSFWNDCISSGLRGCILI ELALRGRLELEKAGMRRRSLLNRKVLLKSSNPTGDVLLDEALKHIKETDPAETVQSWIEY LSGETWNPLKLRYQLRNVRERLAKNLVEKGVC---------------------------- ------------------------------------------------------------ ------------------------------TKDNCEVCVTVIDKFEKTLKKLEKLFMKFC KDLRGKEERFCYYIGGLKTSATYILGTMSKPMKSFMPSTKICEKLRGADNQICDLKYDKQ IDLTKVNLKKLKVKDLKKILSDWGEACKGCAEKSDFIKKVEELMPQYA-------IMKGF KLNWMNLRDADNGKILWQSSDDLSAPGQDHEARVPKKILKCRAVSREINFSSKEAMDKFR LEQRVLFKGKCLEEWFFEFGFVIPGSTNTWQSVIEAAPESQMMPANVLTGNVIIETHFFD GDLLVSKSKVKIFYVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXX-------------------------------KNWQWFIDETRLYSALEEDRLC ERILSYNFDDER------------------------------------------------ ---------------------------------------MFLPADITSEKEVKEVLATME NYKCLDVLVNCAGIGVARKTYSIQKNLPHPLDEFERVLKVNTLGTFNMIRQAVILMAQNE PNEDKARGVIINTSSVAAFDGQMGQVAYAASKAAIAGMTLPLARDIGEFGIRVCTICPGV FDTPLLAALPQKGIDALTKTVVFPQRL-------------------------------SR DFHFKFQR---NQADQISKQYPVIDHTFDAVVVGAGGAGLRAAFGLANEGFKTACITKLF PTRSHTVAAQGGINAALGHMEEDHWHYHFYDTVKGSDWLGDQDAIHYMCEEAPKAVIELE NYGMPFSRLENGKIYQRAFGGQSINYGKGGQAHRCCCVADRTGHSLLHTLYGRSLKYDTS YFI--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXKMGAKYDPQAEAEVRHWFKQLLNEGSMTVEK NLKDGILLIKLLQKLACDKIKLKFNTSQAPFKQMENIELFLKGANAYGVPDNSLFQTVDL YEGRNMAMVIATILQVGTEAQRNGFQGETAGNKPVEKNVRDFSYAQLKSGHLQAGTNKLD SQAMGAVRHISDIRADKFDKTSEGVITLQAGNQWASQKGMAIGAVRHISDLKVSQACQEG QATISLQSGTNKFDSPKGRGFGAVRHINDIRADDLLLEG--------------------- ------------------------------------------------------------ ------------------------------------------------------------ -AYSFGATPITCHAWNGKGDEIAIKNDQNIEIYKKGYDQTATLSEHGQRVTGIDWEPQHN RIVTSGADRNAYVWPCLVILRINRAASCVKWSPNGDKFAVGSGSRLVSICYFEEENHWWV SKHIKKPIRSTITCLDWHPNNVLIAAGSSDFKARIFSAYIKEVESKPTSTCWGAKMPFAN CMFEVSNGGGWVQDVSFSASGELLAFVGHDSSISVVNGVLKGAFLPMLSLTWIGPHSIVA AGHDCVP----------------------AMNRFRNLDKKATELKTKHQNTITQVSIYSG TKDNCNKFCTAGKDGQMIIWDVKSEDDEFIGFATLPDQVHRKAVKRGFEFSFMVVGETGL GKSTLISSLFLTDLYKD------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------MSRRYDSRTTIFSPEGRLYQVE YAMEAIGHAGTCLGILANDGVLLAAERRNTNKLLDEVSYSEKIYKLYNDMACSVAGITSD ANVLTNELRLIAQRFHLQYQEPIPCEQLVSSLCDLKQAYTQFGGKRPFGVSLLYMGWDKH YGFQLYQSDPSGNYGGWKATCIGNNSANAVSMLKQEYKEGEMNLNDALLLAIKTLSKTLD MTKITADKVEIATLTREDGQTKMTILGAPAVEEVIKKHEEIEAK---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------DNSAF LQFLWKTDVVESWIADKETQVRSDDYGRDLSSVQTLLTKQETFDAGLQAFEKEGIQTITS LKDQLIQAQHAQTPAIQKRYNDVMERWQKLLNDSEGRKQRLLRLQDKYRQIEDLYLTFAK KASAFNSWFENAEEDLTDTVRCNSVEEIKYLRENHDQFKASLSAAQADFNQLAALDKQIQ GFQVGTNPYTWFTMEALEDTWKNLQRIIKERDVELSREQQRQEENDQLRKQFAQAANAFH TWLTETRAAMMEGSGTLEDQLEATKQKAAEVRS--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------DMVQYYPSEIAAAALCLSMKLLD WTDTLEHYSSYSEEDLSPLMKKLCSLVIK------------------------------- -XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSPTLTVGG DRTTGQSVRTQNVLAASSIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEH PAAKVLVELAELQDQEVGDGTTSVVIIAAELLKNADELVKCRIHPTSIISGYRLACKEAC KYIQEHLTINVEELGKECIINAAKTSMSSKIIGSESDFFSNMVVEAANAIKTSDGKGGYK YPIKAINVLKAHGKSSKESTMVHGYALNCTVASQAMTKKVVGAKIA-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---EENVARLLASKNVLNQYLVEGRDLTVQYTIFNIGGSAALDVNLKEESFPEQDFEVVK GNLNVKWERIAPGTNVSHVXVLRPLQFGYFNFTAAEVSYKPSENSAVVGFTSAPGEGGIV GSKDFDRKFSPHVLDWLVFAIMTLPSLTIPFLLFYRSKSRYDTPKPKKNXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXMKLTDNVVRNYRVAKIFRENTDRINRIDFSSDGNTLISSSDDDSIVIYD CQNGTPKKTLNSKKYGVDLICYTHAVNTALHGSTKVDDTIRYLSLHDNKYIRYFPGHTKK VVSLNMSPINDSFLSGSLDKTIRLWDLRSQNCQGLMHLPGRPVAAFDPEGLIFAAGINSE CVKLYDLRSFDRGPFTTFKLTQDKDCDWTGMKFSPDGKLILISTNGQILRLIDAFQGTPL QTFMGFQNNKGIPLEASFSPDSRFAFCGSTDGRIHCWNTETGVKVAVMNADHPGPIQCLQ FNPKYMMLASACSNMAFWLPYIDDEYIIVEKKGEKNNVGFIQLNRPKALNALCKGLMSEL DQAVQKFEKDDDVGCTVLTGSDRAFAAGADIKEMQTKEFSDVWRGNFLSEWDALSRCSKP VIAAVNGFALGGGCEVAMMCDIIYAGDKAQFGQPEITLGTIPGAGGTQRLCKAVGKSKAM EMVLTANRISAEKAEKAGMVSKVVPAAELVNEAIKTAEKISSFSKIATGMCKEAVNAGYE MTLKEGLHFEKRLFHASFASNDRREGMTAFSEKRPPKFTD >Cristatella_mucedo XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----RGLQTTAVRQDIDQAAKYIGAGAATV GVAGSGAGIGAVFGNLVIGYARNPGLEQQLFSYAILGFALSEAMGLFCLMMAFLLLFAFM AYAKD-SKAPEAQIHRIRITLTSRNVKSLEKVCADLIKGAKDKQLKVKGPVRMPTKILRI TTRKTPCGEGSKTWDRFQMRIHKRLIDLVSPSEVVKQITSISIEPGVEVEVTIADMDQVM AFIEPGKQFAKDSIRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNII VMATQVSKKRKFVADGLFKAELNNFLMRELAEDGYSGVEVRVTPTRTEIIILATRTQSVL GEKGRRIRELTAVVQKRFGFPEDTVELYAEKVGNRGLCAIAQCESLRYKLLGGLAVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGNPPNEFVDKAVRHVLLRQ GVLGIQVKIMLPYDATGKNGPKKPLPDNVNIVEPKDEAVPASPYSETRGVKMSKRGRGGT SGGKFRIPLGLPVGAVMNCADNTGAKNLYTIAVFGVKGRLNKLPAAGVGDMILCSVKKGK PELRKKVMPAVVVRQRKAFRRKDGVFIYFEDNAGVIVNNKGELKGSAITGPVAKECADLW PKIASSSGSIRKGAKEAVSLGPQVLEGEKVFGVAHIFASFNDTFVHVTDLSGKETICRIT GGMKVKADRDESSPYAAMLAAQDVAEKCKTIGINALHIKLRATGGNRTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRLMAKPRGLHTARKMRNTRRAQRWNDKD YKKSHLGTRWKANPFGGSSMAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKVTAFVP NDGCLNFIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALFKGKKERPRSEGA ATLRTRQLFSNRLLNRKQMIVDVLHPTKPTIPKTEVREKLARLFKTTPDVVFCFGFRSQF GGGKTTGFALIYDSLNDAKKFEPKYRQARHGGRKQRKERKNRQMKVRGTAKAKVGAMPRI PTIYSRTYAAPKRPFEKERLDQELKLLGEYGLRNKREIWRVRLTLAKTRKAARELLTLDE KDQKRLFEGNALLRRLVRIGVLDESKMKLDFVLGLKVEDFLERRLQTQVFKLGLAKSIHH ARILIRQRHIRVRKQVVNIPSFVVRLDSQKHIDFSIASPYGGGRPGRVKRKNLKKAESGG GNMGNTIQKLLAGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVTEAKEELMRMLEEDELRD AVLLVFANKQDLPNAMNAAEISDKLGLHNLRNRSWYIQATCATNGEGLYEGLDWLSNSLK NAKMPLAKDLLHPSFEEEKRKCKIKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRKKQHMVRMNALADALKAINNAEKRGKRQVMIRPNSKV IVRFLKVMMKHGYIGEFEIVDDHRAGKIVVNLNGRLNKCGVISPRFDVKINSLEEWSNNL LPSRQFGFLVLTTSGGIMDHEEARRKHLGGKILGFFFMGRMHTPGKGISKSALPYRRSVP TWLKLTSDDVKEQIFKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKCKGLAPE IPEDLYFLIKKAVAIRKHLERSRKDKDGKYRLILVESRIHRLARYYKTKRVLPPTWKYES ATASALVA--ELPEIKLFGKWSTEDVQVSDISLQDYIPIKDKYAKFLPHSAGRYQVKRFR KAQCPIVERLTCSLMMHGRNNGKKLMAIRIVKHCFEIVHLLTGENPLQVLVNAIINGGPR EDSTRIGRQGTVRRQAVDVSPLRRVNQALWLLCTGAREAAFRNIKTIAECLADELINASK GSSNSYAIKKKDELERVAKGNRMNEQMTLRGTLRGHSGWVTQIATTPLYPDMLLSASRDK SLIMWKLTRDQSYGIPQRALKGHSHFVSDIVMSSDGQFALSGSWDSTLRLWDLSTGATTR RFVGHTKDVLSVAFSADNRQIVSGSRDKSIKLWNTLGVCKYTIEECHPEWVSCVRFSPNT ANPIIVSSGWDRVVKVWNLTNCKLKTNHYGHTGYLNCVTVSPDGSLCASGGKDGRAMLWD LNDNKHLYTLEAGDIISALTFSPNRYWLCAASGPTVKIWDLEGKLLVDELRPDVISTSAR QPDCLSLAWSADGQTLYAGYSDXAIRVWQVSMAARMREYKLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTYNDLRDLREQILRVKDTTEVPMIVVGNKCDLEDERVVGKLANEWHCIFMETSAKKK IAVNEIFFDLVRQINKKNPGKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMAALPMNPKPFL NGLTGKPVMVKLKWGMEYKGYLVSVDGYMNLQLANTEEYIEGALAGNLGEVLIRCNNVLY IRGVEEEDEEGEMRDG------------AAGATMDVNTALQEVLKTALIHDGLARGLHEC AKALDKRQAHLCVLASNCDEPMYVKLVEALCAEHGINLIKVDDNKKLGEWAGLCKIDKQG QPRKVVGCSCVVVRDYGKESQALDVLNQYFKSR-MAAIRKKLVIVGDGACGKTCLLIVFS KDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSI DSPDSLENIPEKWTPEVRHFCPNVPIILVGNKKDLRHDPNTIRELAKMKQEPVKLEQGRA VSESITAFGYLECSAKTKEGVREVFETATRAALQVKKKKRGKXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMYSSSAKIVKPPNEKPDEFEQSISQ ALLELEVNSDLKAQLRELNITAAKEVDVGGKKSIVIFVPVPQLKAYQKIQTRLVRELEKK FSGKHVVFIAQRRILPKPTRKSKTKQKQKRPRSRTLTAVHEAILDDLCYPAEIVGKRIKI KLDGSRQFKVYLDKNQQTNVEHKLDTFASVYKKLTGKDVAFEFPEYMLTRGNFRGGFGGR GRGRGRGRGRAKEGEKEWVPVTKLGRLVKDMKIKSLEEIYLFALPIKEYEIIDYFLGSAL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDHNGHVGLGVKCSKEVATAIRGAIILAKLSI IPVRRGYWGNKIGKPHTVPCKVTGKCGSVLVRLIPAPRGTGIVSAPVPKKLLVMAGIEDC YTAARGCTATLGNFAMATYNAVAETYAYLTPDLWKETVFTKPPFQEFTDYLAKMSGGLEA LSLKETDVTKFLACGSHIGSSNVDFQMQQYVFKRRPDGIYIINLRKTWEKILLAARAIAA IENPADVCVISARNYGQRAILKYASATGATPVAGRFTPGTFTNQIQSAFREPRLLVVTDP RSDHQPVTEASYVNIPVIALCNTDTPMRFVDIAIPCNNKSVHSIGLMWWMLAREVLRLRG TISRDIPWDVMVDLYFYRDPEEVEKEAPEPDWSGETVAAGVPVPTTDWSA-AADDWAASG ATTDWGAMKFNKLVSSSRRKQRKRHFQAPSHIRRKIMSSPLSKDMRQKYRVRSLPIRKDD EVQVVRGHYKGQQVGKVVQVYRKKFVVHVERIQREKANGATVYVGIHPSKVVIVKPKLDK DRKKILERRARAR--GKHTEESI---SATTVGSGLKSRKPTAAGVGSAGMWKFYSEDSPG IKVGPVPVLVMSLLFIASVFMLHIWGKYQR-KGDKKKKSAINDVVTREYTIHVHKRIHGI GFKRRAPRSIKAIREFAVKTMGTKDVRIDTRLNKHMWSKGVRNVPYRVRVRLARKRNEDE DSPNKLYTLVTYVPVTTFKGLQTINVDNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNPEKLKARIGGKGSARRKKKVIHRTATTD DKKLQSSLKKLAVNNIPGIEEVNMIKDDGTVIHFNNPKVQASLAANTFTINGHAETKALT DLLPSILQQLGGDFYHQGKTLAKPPKTIEESDENVPELVGNFDEPSK------------- ------------------------------------------------------------ -----------------------------------------------VNAAPLMRRRTYR AHGRINPYMSTPCHIELILGEREDAVSKPAKKRESKKKLKRQKMLNREXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXMGISRDKWHKRRPTGGRKEPIRKKRKFELGRAPAQTKLGP KRIHTIRTRGGNKKYRALRLDTGNFAWGSEGRTCKTRIIDVVYNASNNELVRTKTLVKNS IVQIDGTPFRQWFEAHYASSLGRKKGQKVTESEDSALNKRSKKTQKKYDARKKLAKVEPA LEEQFTGGKLLACIASRPGQCGRCDGYVLEGQELQFYLRKLKAKKGKMSLLVPEKFQHIL RIMNTNIDGRRKILYALTAIKGIGRRFAFAICRKADVDLSKRAGELTEEEVDKVITVMGN PRQYKIPDWFLNRQKDIKDGKYSQVLANNLDNKLREDLERLKKIRAHRGLRHFWGLRVRG QHTKTTGRRGRTVGVSKKKDSESGTDSDDE------TGQQSADGDASGKQGKQSRSEKKA RKAMSKLGLKQVTGVSRVTIRKSKNILFVINKPDVYKSPASDTYVVFGEAKIEDLSQQAQ MAAAEKFKSDAQVDEVGVESKDIELVMSQANVSRSRAVKALKNNNNDIVNAIMMGRVRTK TVKKASRVIIEKYYTRLTLDFHTNKRICEEIAIVPSKPLRNKIAGFVTHLMKRIQAGPVR GISIKLQEEERERRDNYVPETSYIEEVDPDTKEMLKALDFPNIPGLQVTQPISNTMKWAY KEEHPFDKRRAEGEKIRKKYPERVPVIVEKAPKARVGDLDKKKYLVPSDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGSLYQEHHEEDFFLYIAFSDESVYGMRDLRIRKL CLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVRSFGIRRNEKIAVHCTVRGPKAE EILERGLKVREYELKKSNFSDTGNFGFGIQEHIDLGIKYDPGIGIYGMDFYIVLGRPGFS VSNRRIKRGKVGPKHKVSKEESMKWFQQKYDGIILPGKMGIKFLEFVKPFCAVLPEISKP ERKIQFREKVLWTAIVLFIFLVCCQIPLFGIMSSDSADPFYWLRVIMASNRGTLMELGIS PIVTSSLIMQLLAGAKIIEVGDSPKERALFNGAQKLFGMVITVGQAIVYVMTGMYGDPAS IGAAICMLIVIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKALSPATVN TGRGTEFEGAIIALFHLLATRQDKVRALREAFYRQNLPNLMNLLATIAVFAIVIYFQGFR VDLPITSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAARFA--------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------QTERAFQKQPTVFLNKKSALLARYYK NIGLGFKTPREAIEGAYIDKKCPFTGNVSIRGRILTGVVLKMKMMKTIVVRRDYLHYVTK YNRFEKRHKNISAHLSPCFRDVSIGDIVTIGECRPLSKTVRFNVVKVAKTSGSKKGFKKF MVNIPKQRRTFCKGKKCKKHTLHKVTQYKKGKDSVVVQGKRRYDRKQSGYGGQTKPVFHK KAKTTKKIVLRMECTECKYRKQLPIKRCKHFELGGDKKKKGQMIQFMGRVIRAQRKGAGS VFKAHTNHRKGAAKLRALDFAERRGFIKGVVKDIIHDPGRGAPLAKVAFRDPYKYKQRIE TFVAVEGLYTGQFVYCGKKAALQIGNVLPVGQMPEGTVVSSLEEKTGDRGALARSSGNYC TVVTHNPETGKTRVKLPSGAKKVVQSSARAVVGIVAGGGRIDKPILKAGRAYFKYKAKRN CWPKVRGVAMNPVDHPFGGGNHQHIGKPSTVSRDTSHGRKVGLIAARRTGRIRGTRDNI- -AKRTKKVGIVGKYGTRYGASLRKMVKKMEITQHSKYTCSFCGKEAMKRKAAGIWACKSC RKIVAGGAYAYSTSAGATVRSAVRRLRE---MGRRPARCYRYCKNKPYPKSRFCRGVPDP KIRIYDLGRKKATVQEFPLCVHLVSDEYEQLSSEALEASRICCNKYLVKFIGKDAFHIRM RVHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVDIGQPIISVRAKEASKQQVI ESLRRAKFKFPGRQKIFVSRKWGFTKWDKEEFETKLAEGLLIADGANVQYKPNRGPLEAW KQAQKVTKILGRTGSQGQCTQVRVEFLDESNRSIIRNVKGPVREGDILTLLETEREARRL RMTKGTSSFGKRHIKTHTLCRRCGRSSYHIQKSKCAQCGYPSARLRKYNWSEKSKRRHTT GTGRMKHLRNVHRRFRNGFREGQVPKAKAVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGAYKYIAELWRKKQSDVMR FLLRVRCWQYRQLSAIHRVSRPTRPDKARRLGYKAKQGYVIYRCRVRRGGRKRPVPKGAT MGKPKNQGINQLKNQRSHQAIAEERVGRKCGGLRVLNSYWVAQDSTYKFYEVILIDPFHK AIRRNPDTQWITKPVHKHREMRGLTSATKKSRGLGKGHGFNHTKGGSRKAFWRKNNYQAM RRKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXLNFLESFTLSGAAAVIAKTCSAPIERVKLLVQNQDEMVKQGRLATPYKGVIDCTV RTYQSEGLLPFWRGNLANCIRYFPTQALNFAFKDSIKQLFKPSKQDSYASSFGKNIAAGG TAGALSLCFVYSLDYARTRLANDAKAVKKRQFTGLIDVYSKTLKTDGIAGLYRGFVISCV GIVVYRGFYFGLYDTLKPIMLGEKASVVLSFLLGWGVTVSAGLLSYPIDTIRRRMMMTSG AAVKYKGSVDCAVQIVKKEGFMSLMKGAGANILRGVAGAGVLAGFDKF---------XXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSIGV PIKVLHEAEGHIVTLETTSGEVYRGKLIEAEDNMNCQLAGLTVTYRDGRVAQLENIYIRG SKIRFLILPDMLKNAPMFKKISAGRGKSAILRAAARGRGRAARG-----MQNDPGENVDM YIPRKCSASNRIISAKDHASIQINLAEVDEKTGRMTGTYKTYAISGAIRRMGESDDSIGR LAKRDGLVAKMVRGPKKHLKRLNXPRHWMLDKLSGVFAPKPSCGPHKLRECLPLIVFLRN RLKYALTYNEVVKITNQRLIKIDGKVRTDITYPAGFMDVITIEKTGEQFRLIYDVKGRFA VHRISKEEAQYKLARIRAVGVAAKGVPYVTTHDGRTIRYPDPLIKVNDTIMVXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---QAKSKK AIESINSRLALVMKSGKYVLGYKQTLKSLRLGKSKLIIIANNSPPIRKSEIEYYAMLAKT GVHHYNGNNVELGTACGKYFRVCTMSITDPGDSDIIRSMPS------LVVVGAGGVGKSA LTIQLIQNHFVEEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYCAMRDQYMRTGEGF LCVFAVNNVKSFEDINLYREQIKRVKDADEVPMVLVGNKVDLPSRQIDSRTAQNFANSVV IPYVETSAKTRQGVDDAFYDLVREIRKYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMKLNVAYPATGSQKTFEIDDEAKLRPFYEKRMSQEMPADSLGEEWKGYIVRITGGND KQGFPMKQGILTNGRVRLLLSKGHSCFRKGRSGERKRKSVRGCIVDAQLSVLNLVILKKG ESDVPGLTDRTVPRRLGPKRASNIRKLFNLSKTDDVRQYVVRRPIAPVTHAPRIQRLVTP VVLQRRRHRLALKKKRISARREDAAEYAKLLAQRLKEAKERKAERRRSASTSKKVRAKDL RGKKKEELVKQVQDLKQELSVLRVAKVTGGAASKLSKIRVVRKSIARVLTVMNQTQKDNL RKFYKPTDIRYKKTRAMRRALTKHETSLKTAKQQRKERLYPARKYAVKAEVKGPKVTDQV YFDISIGGESAGRITIGLFGKTVPKTVKNFVGLCTHE-GYKGSKFHRVIKNFMIQGGDFT RGDGTGGKSIYFADENFKLKHYGAGWLSMANAGPDTNGSQFFLTTVKTQWLDGKHVVFGK VLSGMSVVRKVEGTSTDRDKPAKDVVISDCGVIAVEEPFEVAKEDATDKKKKTAIKFTLD CTRPVEDGIMDVADFEKFLKQKIKVDGKAGNLKNKLIITCSITFSKRYLKYLTKKYLKKN NLRDWLRVVAATKDSYDLRYFQINNEEEEEEED-XXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXMSYMLQHLHNGWQVDQAILSEEDRVIVIRFGHDWDPACMVMDETLY RCAEKIKNFAVIFLVDVTEVPDFNKMYELYDPCTSMFFYRNKHIMIDLGTGNNNKINWPM EDTQEFIDIVETVYRGARKGRGLVVSPKDYSTKYRYKKLQRQLEFLEVQETYIKDEQKNL KKEYLHAQEEVKRIQSVPLVIGQFLEAIDQHTGIVGSTTGSNYYVRILSTIDRELLKPSA SVALHKHSNALVDVLPPEADSSITMLRADEKPDVAYSDIGGMDVQKQEVREAVELPLTHF DLYKQIGIDPPRGVLMFGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVR DVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTVNVKVI MATNRADTLDPALLXPGRLDRKIEFXLPDRRQXRLIFSTIT------------------- --------------------------------------------------XXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXX------------FITVDANAEECFFDKVPSGTKMSLIFEVAEGGFLDI DVKISGPEGKQIYSGERESNGRYTFAAHMEGVYKYCFSNKMSTMTPKTVMFRMEVGDAPK EAHNKLESSINELSQALTAVKHEQEFMEVRERVHRAINDNTNSRVVLWAFFEALVLVAVV LGQIYYLKRFFEVRRVIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXTPPFDARFPNQNQTRNCWQNFVDFHRCVKKDDPA PCDYFKKTYKSLCPKAWHEKWEGQVESGTFAGKI-KDYLGKDQRKAKDDEKEDKPIQSLD EGDIEILKTYGVGQYSKSIKTAEDDIQKVMKRVNELCGIKESDTGLAPPTLWDLAADKQT LQSEQPLQVARCTKIINADSDDPKYIINVKQFAKFVVDLGDQVAPTDIEEGMRVGVDRNK YQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPEKFVKLGI DPPKGVLCYGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMART KKACIIFFDEIDAVGGARFDDGAGGDNEVQRTMLELINQLDGFDPR-------------- ------------------------------------------------------------ -----------------------------------------------MGSDKTHINIVVI GHVDSGKSTTTGHLIYKCGGIDKRQIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITI DICLWKFESKNFYITIIDAPGHRDFIKNMITGTSQADCAVLIVASGTGEFEAGISKNGQT REHALLAFTLGVKQLIVGVNKIDSTEPPYSSARYEEIKSNVSEYIKRIGYNPEAVPFVPI SGWHGDNMINLPWFKGWKIFSGKTLLEALDAIEPPVRPTSLALRLPLQDVYKIGGIGTVP VGRVETGVLKPGMVVTFAPCDLSTEVKSVEMHHEVLAEAVPGDNVGFNVKNIAVKDLRRG FVAGDSKNNPPRETDTFYAQVIIMNHPGQISXGYAPVLDCHTAHIACKFVEIKEKIDRRT GKCTEELPKFVKSGDAAMVTMKPQKPMCVEPFAQFAPLGRFAVRDMKQTVAVGVVKXVTK KDPNAAXVTK-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPKE IKEIKDFLLTARRKDAKSVKIKKNVKFKVRCSKYLYTLVIQDREKADKLKQSLPPGLAVK ELKMSKISRDSLRETVDQLLVKARKFTETVELQVSLKNYDPQKDKRFSGTVKLKYVPKPR MKICIIGDQQHQDEATANNIPCINMEDLKKLNKDKKLVKKLAKKYDAFLASDSVIKLIPR VLGPGLNKAGKFPAMLTHGESMVAKVDELKASIKFQMKKVLCLAVAVGHVNMTGEELTSN ITMSINFLVSLLKKNWQNVRALYIKTTMGPSQRIYXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------HKPD SQPVGLVVNPNRTIAAAADAYSCEFGSSTYYAYCGLGGILSCGLTHTAVVPLDIVKCRLQ VDSAKYKNLGTGFRISVQEEGIRGLAKGWAPTLIGYSAQGLCKFGFYEMFKIVYGNAIGE ENAYLWRTSLYLAASASAEFFADIALCPMEAVKVRMQTKPGWASTLRQGFPIILREEGIG GFYKGLVPLWGRQIPYTMMKFACFERTVEVLYXYVVPKPRSECSKPEQLVVTFAAGYIAG VFCAIVSHPADXIXSKLNQX---------------------------------------- -------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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SYIEGYSPPQADTGVFEALAAPSSDYAHALRWYNHILSYGGDRNSFPGQKNAVPSSGSAK SKAKADDDDIDLFGSEAEKIKQQRVDEYAAKKAPAIIAKSSILLDVKPWDDETDMKKMEE CVRSIELDGLVWGAGKLVPVGYGIKKLQIMCVVEDDKVGTDLLEEKITAFEDLVQSVDVA AFNKI------XVTRIERIGAHSHIRGLGLDDALVARQISQGMVGQQEARRAAGIIVEMI KEGKISGRAVLIGGPPGTGKTAIAMGMAQSLGLDTPFTAMAGSEIFSLEMSKTEALTQAF RKSIGVRIKEETEIIEGEVVXIQIDRPATGTGAKVDKLTLKXXEMXTIYDLGQKMIESLT KEKAXAGDIITIDXATGKITXLGRSFTRARDYDAXXPQTRFIQCPEGELQXRKEVVHTVT XHEIDVINSRTXGFLALFSGDTXEIKS--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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------------------------------------------------------------ ------------------------------------------LRLPLQDVYKIGGIGTVP VGRVETGIIKAGMIVTFAPVNLTTEVKSVEMHHQALEEAVPGDNVGFNVKNVSVKDIRRG NVAGDSKNDPPKETEEFKAQVIILNHPGQINAGYAPVVDCHTSHIACKFRELLEKIDRRS GKKLEDNPANVKSGDAAIVEMVPQKPMCVEAFADYAPLGRFAVRDMRQTVAVGVIKSVKK RDGGQGKVTKAAQKAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------TAKEIYQKIQDGVFDVNNEANGIKL GPHQPANKGTGGGAGNQGSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXMSDAEGDDVPS--VEAGSMDISTALQEVLKTALIHDGLARGLREC AKALDKRQALLCILANNCNEPMYKRLVEALCAEHGINLMKVEDNKKLGEWSGLCKIDKEG KARKVVGCSCVVVKDFGKETQAHDVVNEYFKSKRXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMYSGSAKIVKPQGEKPDEFELSISH ALLELETNSDLKAQLRELYITGAREVEVQGKTAIIISIPPPQLRAYQKIQTRLVRELEKK FSGKHVVFIAQRRILPKPTRKTRRKNKQKRPRSRTLTAVHDAILEDLVFPAEIVGKRIRI KLDGSRLIKVHLDRNQQTNVEHKIDTFSAVYKKLTGKDVNFEFPE--------------- -------------GGQEWIPVTKLGRLVKDMKIKTLEDIYLFSLPIKEFEIIDFFLGSSL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDFNGHVGLGVKCSKEVATAIRGAIILAKLSV IPVRRGYWGNKIGKPHTVPCKVTGKCGSVVVRLIPAPRGTGIVSAPVPKKLLNMAGIDDC YTSARGQTATLGNFAKATYAAIAQTYSYLTPDLWKETVFTKSPYQEFTDYLAKXXXXXXX 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EMLPGILNQLGAESLANLKKLATVTGDIDEDDDDVPDLVENFDEASKGEMTRYSLNAENP SKTAMARGSHLRVHFKNTRETAHTIKGMHLRRAVAYLKNVVGMKECVPFRRFNGGVGRCA QAKHFKTTQGRWPKKSAEFLLQMLKNAESNAEFKGLDTDHLMIEHIQVNRAPKMRRRTYR AHGRINPYMSSPCHIEMMLVEREQAIAKPSKKKVSQKKLRKQKQQMRDXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXMGISRDKWHKRRATGGRQNPIRKKRKYELGRPAANTKLGP KRIHTIRTRGGNKKYRALRLDTGNFSWGSEAQTRKTRIIDVLYNASNNELVRTKTLVKSA IVQVDAVPFRQWYEAHYATPLGRKKGVKLTESEEAVLNKRSKKTQKKYDERKKTAKVETA LEEQFGAGRLLAAISSRPGQSGRCDGYVLEGKELEFYLRKLKSKKGKMSLVIPEKFLHIL RVMNTNIDGGRKVAFALTAIKGIGRRFATIVCKKADIDMNKRAGELSEEEVEKLITIIAN PRQYKIPDWFLNRQKDVVDGKYSQVMSNALDNKLREDLERMKKIRAHRGLRHYWGLRVRG QHTKTTGRRGRTVGVSKKK---SDSDSDEDVPDLEDIAQAAGLPEELVSKAKQSRSEKKA RKAMSKLGLKPVQGVSRVTIRKSKNILFVISRPDVYKSPASDTYIVFGEAKIEDLSQQAQ VRAVDQFKNDEEIDETGVEAKDIELVMSQANVTRAKAVKALKNNQNDIVNAIMXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMRWEY KEEHPFEKRRAEGEKIRKKYPDRVPVIVEKAPKARVGDLDKKKYLVPSDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGALYQEHHDEDFFLYIAYSDESVYGMRELRILKL CLNICVGESGDRLTRASKVLEQLTGQQPVTSKARYTVRSFGIKRNEKIACHCTVRGAKAE EILERGLKVREYELRKNNFSQTGNFGFGIQEHIDLGIKYDPGIGIYGMDFYVVLGRPGYS IPHRKHKRGVIGPKHKVSKEESMKWFQQKYDGVILPGKXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQTERAFQKQPNVFLNKKRGLQPRYVK NIGLGFKTPREAIDGHYIDKKCPFTGNVSIRGRILNGVVIKMKMNRTIVIRRDYLHYIRK YNRFEKRHKNMSVHLSPCFRDVSLGDVVTAGECRPLSKTVRFNCIKVTKTSSDKKGFSKF XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRVIRCQRKGAGS VFKAHTKNRKGAARLRAVDYAERHGYIKGVVKDIIHDPGRGAPLAKVTFRDPYRYKLKSE TFIASEGMYTGQFIYAGKKANLQIGNILPVGVMPEGTIVCCMEEKAGDRGRLAKASGNYA TVVSHNPETKKTRVKLPSGSKKVVPSANRAMVGIVAGGGRIDKPMLKAGRAYHKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGKASTVRRDTSAGRKVGLIAARRTGRLRGSKASIG KAKRTKKVGITGKYGTRYGASLRKTIKKMEITQHGKYTCSFCGKEAMKRRAAGIWGCRSC RKVVAGGAYVYSTTAAATVRSAVRRLRELKEMGRRPARCYRYCKNKPYPKSRFCRGVPDA KIRIFDLGRKKARVDEFPLCIHLVSDEYEQLSAEALEAGRICANKYLVKNVGKDTFHLRM RPHPFHVVRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQPLMSVRARENSKDHVI EALRRAKFKFPGRQKIFVSSKWGFTKWERPAYETMRADGRLIPDGVSVQYKPSKGPLQAW ----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSIGV PIKVLHEAEGHVVTCETKTGEVYRGKLVEAEDNMNCQMTNITVTYRDGRVNQLENVYIRG SKIRFLILPDMLKNAPMFKKVGAGRGKSAILRAAARGRGRGGRGGN---XXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXMARGPKKHLKRLHAPKHWMLDKLGGVFAPRPSSGPHKMRECLPLMIFLRN RLKYALTYDEVKKILYQRLIKIDGQVRTDKTYPAGFMDVITIEKTGENFRLIYDVKGRFA VHRISPEEAKYKLCKVRKVAVGPKGVPFIVTHDGRTLRYPDPLVKVNDTVKLXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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TNQHRDSYASYMGHFDMLNYFALVENEAKARVRFNLMERMLQPCGPPPERPEDMKVELCS FSGFKIYPGHGKRVIKTDGRAFVFINGKCEKSHLMKRNPRKINWTVLYRRKHKKGQQEEV SKKRTRRTAKFQRAITGATLADIMAKRNQKPEVRKAQREQAIRAAKEKQKAKDGGRPRVG GKRMKLNVSFPATGCQKLIEEDDERKLRIFYDKRISAELAADALGDEWKGYRLRITGGND KQGFPMKQGVLTTQRVRLLLGKNHSCYRPRRSGERKRKSVRGCIVDANLSVINLCIVKKG ETDIPGLTDTTIPRRLGPKRASKIRRLFNLGKEDDVRQYVVRRPLAATTKAPKIQRLVTP LVIQRKRHRLSLKKKRAAKKRDDAADYAKLLAQRMKEAKERKMERRRSASHSKKVXAKEL RXKRKEDLLKQLDELKXEXSQLRVAKVXGGAASKLSKIRTVRKSIARVHTVVHQTQKENL RKFYKPKDLRKRKXRAIRRQLTTHEKSIKTHKQQXKDRIYPMRKFAXRXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXMSYMLQHLHNGWQVDQAILSEEDRVVVIRFGHDWDPTCMVMDETLY QVAEKVKNFAVIYLVDITKVPDFNKMYELYDPCTVMFFYRNKHIMIDLGTGNNNKINWAM EDEQEFTDIVETVYRGSRKGRGLVVSPKDYSTKYRYXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAHQPYTLDAI RDRVLLVLKLYDKVTAEKLTLDSHFMNDLGLDSLDHVEVIMAMEDEFGFEIPDADAERLL RPADIVQYIADKEDVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXTAPFDARFPNQNQTRNCWQNFVDFHRCQKVEDYE PCDYFKKVYRSLCPNAWVEKWTEQLEAGTFAGKIXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPTQKVHINIVVI GHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITI DIALWKFETAKYYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQT REHALLAYTLGVKQLIVAVNKMDSTEPPYSQNRFEEIQKEVSSYIKKIGYNPDTVAFVPI SGWHGDNMLKMSWFGGWKKXDWPTLLAALDSIEPPKRPTXQPLRLPLQDVYK-------- -----------GMVVVFAPVNVTTEVKSVEMHHTALEKAGPGDNVGFNVKNVSVKEVRRG NVCSDSKNDPAKETDEFKAQVIILNHPGEIRKGYSPVVDCHTAHIACKFDTILEKIDRRS GKKLEENPEKVKSGDSALVEMKPSKPMCXEAFSDYAPLGRFAVRDMRQTVAVGVIKSVKK KEAGAGKVTKAAQKAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---- ----------------------------VRCSRYLYTLVVPDREKAEKLKQSLPPGLAVK ELK--KLSREGLNEAVAAMLAKKRKFTETVELQVALKNYDPQRDKRFAGTVKLKHIPRPK MRVCVLGDQQHIDEATSNSIPCXDVESLKKLNKNKKLVKKLAKEYDAFLASDTLIKTIPR ILGPGLNKAGKFPTMLTHNESMVGKVEEVRATIKFQMKKVLCLAVAVGHVGMTHXELXAN ISLSINFXVSLLKKNWQNVRALYIKSSMGALQ---XXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------FGGGSLTALPIIE TQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQIKAMKQVAG SMKLELAQYREAAAFAQFGSDLDAATQQLLNRGVRLTELLKQGQYVPMAVEDQVAVIYAG VRGMLDKLDPSRITSFEKGFMAHIRASHQDILKSIRETSSITPETDAKLKDIVLKFLEGF -----------------------------------------------------VEPPSIG STXDERGNTKPVAFMPYRVNGQYIMEGLASSFLFTMGGLGFVILDQTNKPGTPKLNRILM FCIAFVCILISFFMCRVFMRMKLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPIIIDARGHLLG 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXQYILTEKRGEKQNVGLIQLNRPKALNALCDGLMTEM KTALMDFDKDPSVGAIVLTGSQKAFAAGADIKEMENLEFPGTYISEFLKGWDQVARTRKP IIAAVNSFALGGGCEVAMMCDIIYAGEKAFFGQPEILLGTIPGAGGTQRLTQAVGKSKAM EMVLTGDKISAHEAEKAGLVXKVFPADQLVDEAVKLXKKXAXNSTLIVMMAKESVNASLK ---------------------------------------- >Euprymna_scolopes MFERKAVIKNSDMSEDMQSDAIECSTQALEKFNIEKDIAAYIKKEFDKKFNPTWHCIVGR NFGRYVTHEAKHFIYFYLGQVAILLFKFG-----RLFQTSSMRNDIDQAAKYIGAGAATV GAAGSGAGIGSVFGNLVIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLILFAF- -------------------------------VCADLIRGAKDKQLKVKGPVRMPTKILRI TTRKTPCGEGSKTWDRYQMRIHKRIIDLHSPSEIVKQITSISIEPGVEVEVTIADXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX X-ATTISKKRKFVADGVFRAELNNFLMKELSEDGYSGVEVRVTPTRTEIIILATRTQNVL GEKGRRIRELTSVVQKRFHFPEGSVELYAEKVATRGLCAIAQCESLRYKLIGQLPVRRAC YGVLRFIMESGAKGCEIVVSGKLRGQRAKSMKFVDGLMIHSGDPVNDYIDTAVRHVLLRQ GVLGIKVKIMLPFDPNGKIGPKRPLPDHVSIVEPKEEVIVQTPYSEHKGAK-----RGGT AGGKFKISLGLPVGAVINCADNTGAKNLYVIAVSGIKGRLNRLPAAGCGDMLVATVKKGK PELRKKVMPAVVIRQRKPFRRKDGVFIYFEDNAGVIVNNKGEMKGSAITGPVAKECADLW PRIASNASSIRKGKAQQVSLGPQVLEGENVFGVAHIFASFNDTFVHVTDLSGKETIARVT GGMKVKADRDEASPYAAMLAAQDVAERCKTVGITALHIRLRATGGNKTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL--EPRGLRTARKLRDHRRKQRWHDND YKKANLGTRYKANPFGGSSHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP NDGCLNFIEENDEVLVAGFGRKGHAVGDIPGVRFKIVKVANVSLLALFKGKKERPRSEST ATLRTRKFLTNRLLCRKQMVVDVLHPGRATVPKTEIREKLARMYKTTPDVIFVFGFRTQF GGGKSSGFGMVYDTLDYAKKFEPKHRLARHGSRKQRKERKNRQKKVRGVAKTKIGAMPRV PLVQSKTYSTPRRPFEKERLDQELKLIGEYGLRNKREVWRVKYSLANIRKGARELLTLEE KDPKRLFEGNALLRRLVRIGVLDESKMKLDYVLGLRLEDFLERRLQTQVFKLGLAKSIHH ARVLIRQRHIRVRKQVVNVPSFVVRLDSQKHIDFSLKSPFGGGRPGRVKRKNMRKAQGGG AVMGNIFDKLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERICEARDELSRMLNEDELRD AVLLVFANKQDLPNAMNAAEVTDKLALHNMRNRTWYIQATCATSGDGLYEGLDWLSX--- ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRMHCPGKGISQSALPYRRSVP TWLKLTSEDVKEQIYKLAKKGLTPSKIGVILRDSHGVAQVRFVTGNKILRILKAKGLAPK IPEDLYHLIKKAVSVRKHMERNRKDKDSKFRLILVESRIHRLARYYKTKRVLPPNWKYES STASALVAAPELPEIKLFGKWSPDDVQVNDISLTDYIAVKEKYSKYLPHSAGRYQLKRFR KAQCPIVERLVCSLMMHGRNNGKKLMTMRVVKHAFEIIHLLTGENPLQVLVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQALWLLCTGAREAAFRNIKTIAECLADELINAGK GSSNSYAIKKKDELERVAKSNR-------------------------------------- ------------------------------------KFALSSSWDATLRLWDLNQGTTSR RFVGHTXDVLSVSFSADNRQIVSGSRDRTIKLWNTLGVCKYTIEDSHPDWVSCVRFSPST ANPIIVSCSWDKIVKVWNLTNCKLKTNHYGHTGYLNTVTVSPDGSLCASGGKDGQAMLWD LGEGKHLYTLDGGDVINALCFSPNRYWLCAATGPSIKIWDLEGKNVVDELRPEVITQS-S QPLCTCLAWSANGQTLFAGYTDNNIRVWQVSTAAR-----------------------VQ GIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTFNDLQDLREQILRVKDTNDVPMLLVGNKCDLEDERVVGKLARQFNCGFLETSAKSK INVNEIFHDLVRLINKKNPER----KM-DSEHVNLKVVGQDGSVVHFKIRKHTALKKLMQ AYCERAGVRPGSVRFMFDGQAIGEKDTPSQLEMEDNDTIDVFQQQTGGXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------------- ----------------VADIEVDXKQVELALWXTAGQEDYDRLRPLSYPDTDVILMCFSI DSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEVTRRELAKMKQEPVKAEEGKS MADKICAFSYLECSAKTKEGVRQVFETATRAALQVKKKKKPRMDDLQAAEENVFVVDDVT NVIKESVESVIGSNAYQHNKINQWTSNVVEQCLSQLTKMNKPFKYIVTCVIMQKNGAGLH TASSCFWDSTTDGSCTVKWENKTMYVIVSVFGLAI------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------HKLEVFRGVYKRLTGKDVVXEFPDFVL------------ ------------------VPVTKLGRLVKDMKIHTLEEXYLFSLPIKEAEIIDFFLGSAL KDEVLKIMPVQKQTRAGQRTRFKAYVAIGDHNGHVGLGVKCSKEVATAIRGAIVLAKLSI IPVRRGYWGNKIGKPHTVPCKVAGQCGSVTVSLIPAPRGTGIVSAPVPKKLLSMAGIDDV YTHARGSTATMGNFAKATYNAIAQTYAYLTPDLWKDNAFTKSPYQEYSDHLAK------- ------------------------------------------------------------ --NPADVCVISARPYGQRPXVEIASATGATPIAGRFTPGAFTNQIQKAFREPRLLVXTDP RTDHQPVNEASYVNIPVIALCNTDSPLKYIDIAIPCNNKSVHSIGLMWWLLAREVLRLRG NISREHPWEVMVDLYFYRDPEEAEKETDVTDWASEAAASAVPIPTEDWSAPEPAEWSVPA ATT----MKLNKSVSSSRRKNRKRHFNAPSHIRRKLMTSPLSKELRQKYNVRNMPIRKDD EVQVVRGHYKGQQLGKVVQCYRKKFVICIERIQREKANGASVHVGIHPSNVVIVKLKLDK DRKRILDRRSRSRVAGKHTEESIVPPSSTNVGSNVKQRKTTTAGGGGAGMWRFYTEDSPG IKVGPVPVLVMSLLFIASVFMLHIWGKYTRG----RKKSSMNEVITKECTIHLHKKVYGV KLKKKAPKAIKKIKMFAERMMRTKDVRIDTKLNKHIWSNGIRHVPFRIRVRLSRRRNEDE DSPNKLYTLVTHVPCVNFKGTQTMNVEN-------------------------------- ------------------------------------------------------------ ----------------MIADQMIVGVGFVHNKNFIHRDIKPDNFLMGIGRHCNKVFMIDF VLAKKYRDSRTRQHIAYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRGS LPWQGLKAATKKQKYEKISEKKMSTPVEALCKGFPAEFAMYLNYCRGLRFEEAPDYMYLR QLFRILFRTLNYQYDYTFDWTMLKQK----MNAEKLKQRIGGKGTARRKKKVVHRTATTD DKKLQSSLKKLTVSNISGIEEVNMIKEDGQVIHFNNPKVQASLTANTFAITGHAETKQIA EMLPGILNQLGAESLSSLKKLANSTEDIDADDDEVPDLVENFDEPSRGEMARYASEAENL SKSAKARGSLLRVHFKNTRETAQAIKRMHLKRAVRYLKSVMERKEIVPFRRFCGGVGRHA QAKQWGTTQGRWPKKSAVFLLQLLKNAESNAEFKGLDTDHLVIEHIQVNQAPKMRRRTYR AHGRINPFMSSPCHIEVILTEKEVPVPKPVRKKVSQKKLKKQKMMMRD------------ ------------DTDGSGTIDAKELKVAMRALGFEPKKEDIKSMIAQVDKNGTGTIDFND FLTIMSQKMSDKDTKEEILKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQEADRD NDGEVNQEEFLRIMKKTSLYMGISRANWHKRKATGGRQVQIRKKRNFELGRPAAMTKLGS RRVHTVRTRGGNKKFRALRLDTGNFSWGSESISRKSRIIDVVYNASNNELVRMKTLVKSC IVTIDGTPFRQWYEAHYALPLGRKKGVKLTEQEEAVLNVRSRKNQKKYIRRKKTAKVEST LLEEFMTGRLLAKITSRPGQIGKSDGIVLEGKELEFYMRKIKAKKGKMTLVIPEKFQHIL RIMNTNIDGRRKSMFAITAIKGIGRRFSNVVCKKANIDLKKRAGELTEEEVDRVLTVMSN PRQYKIPDWFLNRQKDIKDAKYSQVMANNLDNKLREDLERLKKIRAHRGLRHFWGLRVRG QHTKTTGRRGRTVGVAKKKDADSDTKSEDSIPELQ-VAQVAGCXEELVSKAKQSRSEKKA RKAMSKLGLKQVQGVTRVTIRKSKNILFVINRPDVYKSPASDTYIVFGEAKIEDLSQQAQ MAAAEKFKAEEEIDETGVEPKDIELVMSQASVSRVKAVKALKNNNNDIVNAIMXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKWQY KDEHPFEKRRAEGEKIRKKYPDRVPVIVEKAPKARVGDLDKKKYLVPTDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPPSATMGSLYQEHHEEDFFLYIAYSDESVYG--------- -----------RFPRPPRVLEKFQGKTPFFFKGGLISEPFGSGGMEKIVSPSLSRGARVG GFFEGGLRVGGFVLGKLFFSEIGNFGLGI------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------ATVFVFAIVIYFRGFR XDLQIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYFISQMLANKFHGNLFVNLLG IWTS-EGGGPARSYPTGGLCYYLSPPDTLTHVVEDPIHAMVYIFFMLGSCAFFSKTWIEV SGSSAKDVAKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIG SGTGILLAVTIIYQYFEIFVKEQSEMGGMSTLLFXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRVIRSQRKGAGS VFRAHTKHRKGAAKLRPIDFAERHGYIKGVVRDIIHDPGRGAPLARVSFRDPYRYKRKTE TFVCAEGLYTGQFLYCGKKATLQVGNILPLGAMPEGTIICSVEEKTGDRGKLARASGNYA TVISHNLETKKSRIKLPSGAKKIVSSTNRAMIGIIAGGGRMDKPLLKAGRAYYKYKAKKN CWPKVRGVAMNPVEHPHGGGNHQHIGKASTVRRDTSAGRKVGLIAARRTGRLRGSKQVTG KXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRRPARCYRYCKNKPYPKSRFCRGVPDP KIRIFDLGRKKARVDEFPLCIHLVSDEFEQISSEALEAGRICANKYLVKHCGKDAFHLRI RLHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQVIMSVRAKEMHETMIV EALRRAKFKFPGRQKIVISKKWGFTKWDRENYGPMRTAGTLIPDGVSVQYKPEHGPLKFW ----RVTKVLGRTGSQGQCTQVRVEFIDDSNRSIIRNVKGPVREGDILTLLESEREARRL RXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------------ ------------------------------------------------------------ --------------------------------QITQVYGXXDECXEKYGNANVWKFFTDL FDFLPLTALVDGQIFCLHGGXSPSIDSLDHIKALDRIQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHSNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRC GNQAAIMELDDALKYSFLQFDPAPRRGEPHVTRRTPDYFLXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXX-------------------------------------------------------- -------------------------------------------------TNKTDLLGIQE LLNEPNIKDPAQAEAYTIYCQNRSEYEKRVRAQAMKFREES-GKSSKMLQHIHYRVRCTM QDGRILXGTFKAFDKHMNLILGDCDEFRKIKPKSSKQREEKRVLGLVLLRGEHLVSMTVE GPPPAEEGIARVPLAGAAPGHGMGRAAGRGVPAAPGLQGPVRGVGGPSQQMMTPQ----- ----EDIXTXKLVLVGDVXVGKTTFVKRHLTGEXEKKYVATLGVEVHPLVFYTARGPVKF NVWDTAGQEKFGGXRDGYYIKGQCAIIMFDVTSRVTYKNVPNWHRDLVRVCQNTPIVLCG NKVDVKDRKVKAKTITFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVEMPA LQPPEVEMSQTLALQYEKELEEAQRIALPDDDDDL------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ KFIGEXSRMXRELFVMPREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLD GFEPKQNIKVIMATNRIDILDPALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRG IDLRKIAEMMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFELAVAKVMQKDSEKNISI KKQWKLGXAENXAXSGAAAIISKTAAAPIERVKLLVQNQDEMLKTGRLKEPYKGVIDCTM KTFKSEGLIPFWRGNMANCIRYFPTQALNFAFKDQIKILFKASKQDSYPLKFGKNIASGG VAGALSLCFVYSLDYCRTRLANDAKSSKKRQFNGMVDVYRKTIASDGVAGLYRGFVISCV GIVVYRGCYFGFYDTLKPIVIGDAANLMASFALGYIVTISAGLVSYPIDTIRRRMMMTSG EAVKYSGSIDCTKQIIANEGFMSLMKGAGANIXRGVAGAGVLSGFDKFKEIYVAFRV--- ------------------------------------------------------------ ------------------------FYQCRNILLLLALKVRYPDRITLIRGNHESRQITQV YGFYDECLRKYGSITVWRYCTEIFDFLSLSAIIDGKIFCVHGGLSPSIQTLDQIRAIDRK QEVPHDGPMCDLLWSDPEDMQGWGVSPRGAGYLFGSDVVSQFNVANDIDLICRAHQLVME GYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHVQRDFTIFEAAPQECRGKPQPDYFL XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXX--------------------------FAPRPSTGPHKWRECLPLIXFLRN RLKYALTSDEVKKIVKQRLIKVDGQVRTDPTYPSGFMDVITIEKTNEHFRLIYDAKGRFA IHRIKTDEAKYKLCRVTRVQTGPKGIPFLCTHDGRTIRYPDPLIKVNDSILL-------- -YLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTA GQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADNNIVIMLVGNKSDL RHLRAVPTDEAKAFAEKHNLSFIETSALDSTNVEAAFQNILTEIYKIVSQKQIRESPDDP NVQTITVAPTDTSVGVKKQCCT-------------------------------------- ------------------------KIPLPDEHVAMAFAGLTADARILINRARVECQSHRL TVEDPVTVEYITRFIAQLKQKYTQSNGRRPFGLSALIVGFDGTPRLYQTDPSGTYHEWKA NAIGRSAKTVREYLKKGYTDEVAKDEECIKLALRALLEVVQSGGKNVELAVLRDNQPLKM MESSEIERYIADIEKEKEEEAEKKKQK--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------KNLVAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPS IVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDARGDVKVIMATNRIETLDPA LIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTLAPDVNIDDYVMAKDDLSGADIKAICT EAGLLALRERRMKVTNEDFKKAKENVLYRKNEGTPEGLYL---------------FVLAR LDDLLNWGRKCSLWPLTFGLACCAVEMMHIAAPRYDMDRFGVVFRASPRQADVIIVAGTL TNKMAPALRKVYDQMPEPRWVISMGSCANGGGYYHYSYAVVRGCDRVIPVDIYVPGCPPT AEALLYGILQLQKKIKRMNTLQMWYRKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------- --ENINSRLALVMKSXKYVLGYKQALKTLRQGKAKLVIIANNSPPFR------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------EQIKRVREGGEVPLVLVGNKNDLPPLSVGTKQEKQVGESFG FPYVGGPPKTRQGVGEAFFSLVGGIGKFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKIEVCS FSGYKIYPGHGKRMVKTDGKVMQFLNAKCERSYKMKRNPRKINWTVLYRRKHKKGQTEEV TKKRTRRTAKFQRAIAGATLSDIMAKRNQKPEVRKAQREQAIRAAKEKQKAKEVRAPRVG GKRMKLTIAFPATGCHKMIEIDSETKLRPFYDKRISAEVSAESLGDEWKGYMFTIAGGND KQGFPMKEGVLSNGRVRLLLFKGHSCFRPLIEGERPTKSVQGCIXSAHLSVQSLVIVNKG EGEIPG------------------------------------------------------ -----------------------------------------------------KVKAKDL RGKRKDELKTQVKELKNELAHLRVAKVTGGQASKLSKIRVVRKSIARVLTVINQTQKEHL RKYYKPKDLRPKKTRAMRRLMTPHEQSLITHRQARKRMLWKVRKYAVKGKASGPKVTEKV FFDISIGDENVGRXVIGLFGKTVPKTVKNFKTLAEGTMTYKGSSFHRVIKDFMIQGGDFT KGDGTGGSSIYFNDENFKLKHYGAGWLSMANAGKDTNGSQFFITTVQTSWLDGRHVVFGV VLEGMDVVRKIESSKTSGDKPMKKVVIADCGSLPVEEPFSVPKKSAEEXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------EEEKTYGSCEGPNAMYVKLV SSDGHEFIVKRDHALTSGTIKAMLSGPGQFSEHETNEINFREIPSHVLQKVCMYFTYKVR YTNSSTEIPEFPIAPEIALELLMAANFLDCXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------ ------------------------------------------------------------ -----------------------------------------------------------F EVCKQM-VLTPLGCFMFDPPXCGKTLYPRSVALPPTAKFTRGVGSEFVPKYLGEGPRLVR DVFGMAKENAPAIIFFDENGAIGTKRFDAQTGADRGVQRILLELFNQMDGFDPPVNVKVI LATNRGGTLDPAFLRPGRLDRKIEFPLPDCRQKRLIFFSLPSKMNLSEEVYLEGFVARPD KISGGDFNAIFQEAGMQAVRGNPFLVLVKGFEKGFKNHVKKGETGPGFYK----LTFENV EKRVLLVFNLYDKIDPNKLSLDAHFMNDLGLDRFDTVEVFMAMEGEFGFEIPDAYADRLL RPCDIVQYFAGKGDI--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------TQAVIFCNTKRKVDWLTEKM REANFTVSSMHGDMPQKDRDNIMKEFRSGASRVLITTDVWARGIDVQQVSLVINYDLPNN RELYIHRIGRSGRFGRKGVAINFVKNDDIRIFRDIEQYYSTQIDEMPMNVADLIXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX------------KHTLTAAMCXQNFESQVVERHNKPEVEVKSS KELLLTPVVISRNEKEKVLIEGSINSLRISIAVKQADEIEKILCHKFMRFMMLRAENFII LRRKPVEGYDISFLITNFHTEQMYKHKLVDFIIQFMEEIDKEVSEMKLAVNSRARLSAEE FLKCF---KSATKSNIXGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVEDRLV TMQIWDTAGQERFQILGVAFYRGADCCVLVFDVTAQNTFKSLEGWRDEFLIQASPRDPEN FPFVVIGNKIDLENRAVSAKRAQGWCHGKGDIPYFETSAKEAINVEQAFQTVAKNALAQE TEVELYNEFPDQIKLTNEQNREGCGCXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPDYLGNEQRKVKEDSEKEKPIQALD EGDIALLKTYGVGQYSKLIKACEEDVQNNLKKVNELTGLKESDTGLAPPALWDLANDKQN LQNDQPLQVARCTKIINADSDDPKYIINVKQFAKFVVDLGDHVAPTDIEEGMRVGVDRNK YQIRIPLPPKIDPTVTMMQVEETPDVTYEDIGGCKEQIEKLREVVETPLLHPERFVDLGI EPPKGVLLFG-------------------------------------------------- KKACIISXDEIDAIGGARXDDGAVGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDT LDPALMRPGRXDRKIEFGLPDHEGRTQIFKIHAKPMNVEKKIRFEMLARKCPNSTGAEIR SVCTEAGMLAIRERRKLATEKDFLNGVHQVIKALAKFSATPRYMTYNMPKEKNHINIVVI GHVDSGKSTSTGHLIYKCGGIDKRTIDKFEKEAQEMGKGSFKYAWVLDKLKAERERGITI DIALWKFETDKYYITIIDAPGHRDFIKNMITGTSQADCAVLVVAAGVGEFEAGISKNGQT REHALLAYTLGVKQMICAVNKMDTAE--YSQTRFDEIVKEVSSYIKKIGYNPKAVAFVPV SGWHGDNMINMSWYKGWSIASGVTLIQALDAIIPPTRPVEVPLRLPLQDVYKIGGIGTVP VGRVETGVLKPGVVVTFAPSGISTEVKSVEMHHEALPEANPGDNVGFNVKNVSVKDLRRG YVAGDSKHCPPKETKQFEAQVIVINHPGQIQAGYSPVLDCHTAHIACKFLELKEKIDRRS GKK------------------------------DFPPLGRFCVCDMRRTLAVGVI----- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GHTGYLSCCRFIDDNQIXTSSGDMTCA LWNIETGNQITSFGGHTGDVMSLSLAPDMRTFVSGACDASAKLFDIRDGICKQTFTGHES DINAITYFPNGFAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLG GYDDFNCNVWDVLKQERAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKIWN------- ------------------------------------------------------------ -----------SSSALLXYDITXRTPFTHLTTWLEDARQHSNPNMVIMLIXNKSDLEARR DVKKEEGEAFAREHGLIFMETSAKTAANVEEAFINTAKEIYQKIQDGVFDINNEANGIKI GPQHSNANTSAGGGGTTGSN---------------------------------------- -------------------CCRVDNSVNQRRLYIMTLGCLYPYRRLGIGTVMLEHVLKIC EEDGNFDNVFLHVQVNNEGAIKFYEKFGFGIVEEKKNYYKRIEPADAYVLQKTF--XXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX------------------KKRRFVESVELQIALKNYDPQKDKRFSGTVKLKYIPRPK LRVCILGDQQHMDEAKLNQVPCMDADALKKLNKNKKLVKKLAKKYDAFLASDSLIKQIPR ILGPGLNKAGKFPTPISHAESMTGKVEETKATIKFQMKKVLCLAVCVGHVKMSPDNLYSN ISLAINFLVSLLKKNWQNVRALYIKSTMGPSQRIY------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------SPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSILTKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFLYGGLNAGRPVTPPRGTVKGK GKMMFKNTVQSGFLSILYSGGSKPLQIWDKNARNGHIKRITVSDIQSIVLEIVGTNVSTT YITCPADHKKTLRIKVPFLVMIIKNLKKYLTSEVQVMDDKGARRRFRASNYQSTTRVKPY ICTMPMRLDDGWNQIQFNLSDFTRRAYGSNYIETIRVQIHSNCRIRRVYFSDRLYFDDEL RGEFKLYIP----------------------IHIRIQQRNGRKTLTTVQGISKDYDLKKI VKACKKEFACNGTVVDHPEYGEVIQLQGDQRVNIRDFLKQIGIDEQLKVHGFXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX---------------------------AARKFTTTAEVSSILEERIXNASAVDLQET GKVLSIGDGIARVYGLKNIQAEEMVEFSSGLKGMALNLEPDNVGVVVFGNDKLIKEGDIV KRTGAIVDVPVGKALLGRVVDALGNPIDGKGALQTDVRARVGTKAPGIIPRTSVREPMQT GIKAVDSLVPIGRGQRELIIGDRQTGKTAIAIDTIINQKRFNTGQDESKKLYCIYVAIGQ KRSTVAQIVKRLTDADAIGYTIVVSATASDAAPLQYLAPYSGCAMGEYFRDNGGHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNPSHGGGSL------- -----LSALMPQEVVSVTGGQIFLGNEXFNKGFRPAFNFGLFLNRVGFGAQAKGLKQGAG SMKLGLGQYREVAAFAQFGFGLDPPPPDLFNRGFWLTELLKQGQYFPLGFGGQVAIIFVG VRGFFGKIDPFKITVFGPQF---------------------------------------- MESMCAIPFIFWVCPPLNLKRPPWGGPPPPLFFFVLGGRSSFLVAGGPPRDVLLAPPGVG SSSVERGNPKPVAFLPCGVFGHSLLEGLASSFLFPPGGLGFVLPAPAAKPRFPRLPRVLL FCVAFFPILXSFIMCRVIMGMK---------------------PTLDELNQKMREAETEP HEGKRKVEALWPIFRIHHQRSRYIYDLFYRRHAISRELYEYCLREAIADKNLIAKWKKQG YENLCCLRCIQTRDTNFQTNCICRVPKSKLEEGKIVECVLCGCRGCSGXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXLVRFLMKLSHETVTIELKNGTLVHGTITGVDVSM NTHLKAVKMTLKNKDPVQLETLSIRGNNIRYFILPDSLPLDTLLIDDTPKAKAKKXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-ILIDARGHLLG RLATVVAKCLLQGQRVVIVRSEGINISGHFHRNKMKYLDYLKKRCNVNPARGPFHFRAPS KIFFRTVRGMLPHNNKRGKEALGRLKAFEGIPPPYNQRKRMIVPSALRIIRLKPGRKYCD LNRLAHEVGWKYQAVTATLEERRKAKSAVFAGRSKLKLALDRKAKKIKKQQKVIEQYGYD GDPAKGKKLFVQRCAQCHTVELGGKHKTGPNLNGFIGRPTGQAPGFSYSDSNKSKGITWT KETLWIYLKNPKAYIPGXKMVFAGIKKEKERADVIAYL---------------------- ------------ILQRRRVHLTLEQASDFYSEHFGKKIFASLVEFMSSGPIICLLLARSH AINIWDELIGPPNTYKAQQICPESIRALYGHDELQNAVHGSENQICAEREIRFFFPESIL DPIQTNQLVKDYLAKTVNPTLLKGLTQLSKVKPSDPVGWLAEWLQNNNPYKPRIQ----- ------------------------------------------------------------ ------------------------------------------------------------ ------EYSCVVKMPSVEFQRXCRDLSQIGESVIISCTKEGVTFSSTGDLGTGNIKLAQS NNVDKEEESVIIQMNEAVSLAFALRYLNFFTKATPLSPQVTLSMSQDVPLVVEYKISDMG YIRYYLAPKIEDQD---------------------------------------------- ---------AQHXGENVVRTIAMDGTEGLVRGESCIDMGDPIKIPVGPGTLGRIINVIGE PIDERGPINTTHFSAIHQEAPPFVEMSVQQEILETGIKVVDLLAPYAKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNELYHEMITSGVISLKDDSSKVSLVYG QMNEPPGARARVALTGLTVAEYFRDEEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLA------------------------FVPADDLTDPAPATTFAHLDATTVLSRGIA ELGIYPAVDPLDSTSRILDPNVVGAEHYEVARNVQEILQNYKSLQDIIAILGMDELFEDD KLTVTRARKIQKFLSQPFQVAEVFTGFPGKYVPLAETIKDFNFVLKGEQDHLPEVAFYMV GNLEEVVAKAGKLVEE-----------------KEGVMVAKKDFTGVKHPEIDVPNLHVI KALQSLKSRAFVNEQFAWRHYYWYLTNEGIQYLRDFLHLPSEIVPATLKRQGPFADR-EY RRAPFGDKKADVGAGSS------------------------------------------- ---------------------------TFDTNADGTLDFRXYICALSVTSXGKVEQKLRW AFTMYDVDGNGXISRQEMLEIVTAIYKMVGTVMKMPEDESTPEKRTDKIFRQMDKNLDGK LSLAEFIEGAKSDPSIVRLLQCDP------------------------------------ ------------------------------------------------------------ ----------------------------------SNVKLYCPKCQDVTXPKSTRHHHTDG AYFGTGFPHMLFMVHPEYRPKRPANQFIPRLYGFKIHPLAYQLQYQAAANFKMGHSNSKR MTNTKGYRRGTRHMFARSFRRHGTIPLSTYMKVYKRGQIVDVKGNGAIQKGMPHKSYHGR TGRIYNVSQHAVGVIVNKRVKHRIIPKRINLRIEHVKPSKCQEDFFKRISECQKLKAQAK ARISLKRKPEGPRKKHFVNITKNKPIVLEPIPYEFVA-----WKDVSPPEPSMKWSDITD RAARTAFWGEMFTGLAMVFGHLLKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAICPAQAITIEAEPRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEF STENREELLYNKEKLLTNGDKWEPEIAANLQADHLYR----------------------- --------------------------------------------LIRKSP-LWXHGVVNH PQISAILDEEEEECYHYLNMVEVEEFEDIKSGYRIKFHFSSNPYFSNDVLCKEFHLAASK STPIIWQDGMDLTKKVRKRKLRPNRTFFSWFLDNKDPSADDIAEVIKDDMWPNPLQYFLA PDIEVEENDDDELDESVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXX------------------------------------------------- ITMKDRQINFDIWDTAGQERYHSLAPMYYRGAQAAIVVYDLTKSDTFVRAQRWVKELRQQ ANPNVLIVLAGNKADMRDVTVEEARIYAQEQKLMYVETSAKSGLCVSDIFLALAEKICMA PPKVDIKEQR-----------------------------------LHNKPTFSQTVLSQN LYLNPQNAAIVQMGELEIQQHYDEFFEEVYVEME-KYGEIEEMNVCDNLGDHLVGNVYVK FRYEEEAEKAVADLNNRWFNGRPILAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKP ISRELRRELYGRTKKSRSRTPPMRRSRSRSRPRRANRSRSRERRR--------------- ------------------------------------------------------------ --------------------------------------------ALAFGDDDADPGAMSR PFGVALLFAGIDHKGPQLFHMDPSGTFIQYDAKAIGSGSEGAQQKLQDVYHKSMTLDEAR KQALTILKQVMEEKLDPTNVEMATVTRENNFQMCSKKELEEVIVEI-------------- ------------------------------------------------------------ -----------------------------------------------------WYHSHPV W-LLLSGIDVSTQMLNQQCQEPFVAIVVDPVRTISAGKVNMGAFRTYPKGYRPADEGPSE YQSIPLNKIEDFGVHCKQYYSLDVSYFKSSLDRKLLESLWNKYWVNTLSSSSFIANAEYT TGQIFDLSEKLEQSEAQLGRSGFMEKKSEDKLSKATKDGCKTTIEAIHGLMSQVIKDWLF NHV-------IKETQRLIAEPVPGISATPDESNARYFHVVVAGPSESPYEGGVFNLELFL PEEYPMSAPKVRFMTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPD DPLANDVAEQWKINEAEAIQKAREWTRLYA------------------------------ ------------------------------------------------------------ -----------------------------------NNVKIAVFFGGMPIKKDEEVXKKNC PHIVXXTPGRILALTKTLVLKHVKHFILDECDKMLNELDMRRDVQEIFRMTPHEKQVMMF SATLSKEIRPVCKKFMQD------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------KSKLSKSNFAVGYSAGDFTLHTNVNDGTEFGGS IYQRVNSKLDIGVNLSWTNGSNATRFGLSGKYILDNDASLNAKINNSSQLGLGYSQKLRD GVVLTLSALVEGKNFNAGGHKLGLGLDLAA------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------KRCLXYGPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIGES ARLIREMFAYARDHEPCILFMDEIDAIRRFSEGTSADREIQRTLMELLNQMDGFDALGQV KIIMATNRPDTLDPALLRPGRLDRKIEIPLPNEQARLEILKIHAQPIAKQGEIDWEAIVK LSDDFNGADLRNVCTEAGMFTIRAERDAVIEEDFMKAVRKVAENKVLESKLDYKPL---- -------------------------YLLYVFLTGVMQFLYILVVGTFPFNSFLSGFISSV GSFVLAVCLRLQVNPQNKAXFTSISPERALADFIFANIILHLVVINFIGXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXVIDHFENPRNVGSLDKNDKNTGTGLVGAPACGDVMKLQIKVDDDG KIVDAKFKTFGCGSAIASSSLATEWVMGKSLKEASEIKNNQIAKELCLPPVKLHCSMLAE DAIKAALNDYKKKN----------------------------PGKIQHILCTGNLCTKES FDYLKTLASDVHVVRGDFDDNLNYPEQKVVTVGQFRIGLCHGHQVVPWGETDSLFMVQRQ LDVDILISGHTHIFDAFEHENKFYINPGSATGAYSASEKNVIPSFVILDIQQSTVVAYVY KLINDDVKVERIEYKKMGKFMKSSKVVLVLSGRYAGRKAVIVKNYDDATQDRGYSHALVA GIDRYPRKVTKRMGKRKMKERSKLKTFVKVLNYNHLMPTRYSIVNLDKSCVNKDAFRDPA LKRKARREVKGKLEEKYKTGKNRWFFQKLRFXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-- ---------KAKAKANRAKKAILKGVNTKRAKKIRTNVRFRRPRTFRQPRDPKYPRKSTC KRDKFDQFRIVKYPLTTESAMKKIEDNNTLVFIVDKKANKHQINQAVKKLYDIDAEKVNT LIRPDGEKKAYVKLVSDYDALDIANKIGIIMAPKQRMRIANQKHSQNVANRGNVPKTLKA SEEKYPVGPWLLALFIFVVCGSAVFQIIQSIRMXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- ----------------------------------TVRDAKHTNXVEXRNXKIVYRRYAGL YFCICVDVSDNNLXYLEAIHNXVEVLNEYFHSVCELDLVFNFYKVYSVVDEMFTAGEIRE TSQTKVLKQLLMLSSLE--TIFAKIIRGDIKTDFVYEDDQCVAFNDISPQAPVHILIIPR KPIAQLSDDEQILXHLLVVARKLAAKGNGFRIVINDGRHGGQSVYYLHVHLFAGRQLSWP PXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XGLYFHIGETEKKCFIEELPDETMVVGRYKVEIFDRNINNYVPTVYGLGVHVEIRDPEDK VIMSRTYAAEGRFTFTSHSAGEHLVCLHSNSSAWFSSGQLRVHLDIQVGEHAVDYQQVQT KDKLSELQLRIRQLLDQVEQITKEQNYQRYREERFRLTSESTNQRVLWWSVAQTIILLIT GFWQMKHLKSFFEAKKLV------------------------------------------ ------------------------------------------------------------ -----------PADMDFDPNSNPXCYKTKDEDVVIQQVDEIRIKIVGTRVDAKDIFAIGT LMDDYLGLVSRLYAKAVFTGYKRGLRNQYEHTALLKIDGVLDRKETDFYLGKKCAYVYKA KRKTNVPGTKDASHIRIIWGKVTRPHGNSGAVRAKFRKNLPARAIGRRIRVMLYXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------- -----------------------------------LXHKKRHAEKVQMKKTIKMHEQKKT KQKNDDVVPEGAVPAYLLDREGQSRAKVLSNMIKQKRKEKAGKWNVPLPKVKGVSETEVF KVVKTGKRQKKAWKRMVTKVTFVGDGFTRKPPKFERFIRPMGLRFKKAHVTHPELRATFN LPIISVKKNPSSPFYTSLGVITKGTVIEVNVSELGLVTQGGKVIWGKYAQVTNNPENDGC INAVLLV----------------------------------IFQFVMTXMMKNSRHPYCV SEYAGHQTSAESWGTGRAVARIPRVRGGXTHRSGQGAFGNMCRGGRMXAPTKTWRRWHRK INVNQRRYAMCSAVAASGVTALVESKGHRVQDVAEMPLVINDKVQEYKKTKEAVTLLRQL KAWNDIEKVYKSKRFRAGKGKMRNRRRIMRKGPLLVYEKDNGIVKAFRNIPGITTINVKH LNLRRIAPGGHVGRFIIWTESAFRKLDNIYGTWKQESKEKTGYNLPMPKMSNSDLTRI-- ------------------------------------------------------------ ------------------------------------------------------------ -----------------TEFSEHYASXGPPDPDNLPEDGNLKTETMVKDNRRYYLDLKEN QRGRFLRVSPRGGPRTHIAIPAQGMIEFRDALTDLLDEFGIEDHD-RSELPENRTARVEG KIFYFDVGSNARGVFLRLTEGGYRSSITIPERAWSRFRDLMAEFADKXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXX----------------------------------- ------------------------------------------------------------ --------------------------------KFSISEVEPKYYADGEDAYAMRRDLAEF IDKD------------------------------------EEHLKRMNPACPSITYDISQ MFDFIAELTDLSCLVFQKYNGTYVPHNKEWMKEKIYIMLRKQAG-MAETAEEKKEPETKR AAHTYPLIRHSDMMDEMKTETMELCVTACEKFSNNNETAAKMIKETMDKKFGASWHAVVG EGYGFEITHEVKNLLYMFFGGNVAIVVWKCS----------------------------- ------------------------------------------------------------ -----------------AAHLGEDCRRRFNRNCPPSRRK-LPQSTRKSVKMSCQEVYENX YKKMXXYCTSVRIIAHTQIRLXKNAQKKAHIAEIQXNGGTIADKVKWARDHLEKPIFIAD VFQQDELIDIIGVTQGKGMKGXTSRWHTKKLPRKTHKGLRKVACIGAWHPSRVQYSVARA GQKGYHHRTEINKKIYRIGRGLHTQDGKVIKNNASTDHDPAEKSITPVGGFPHYGELNQD FLMLKGCVMGTRKRIITLRKSLLTHFRRKALEKITLKFIDTASKYGNGRFQTLLEKKNFM GPLKKD-------------------------------YIPTVXDNYTANVMVDGKPINLG LWXTAGQEDYDRLRPLSYPQTDVFLICFSLISPASFENVRAKWYPEVCHHCPNTPIILVG TKLDLREDKETVEKLKEKKLSPITYPQGLAMAKEITAVKYLECSALTQKGLKTVFDEAIR AVLCPKPKPNKRNRCKI------------------------------------------- --------------SLSMKKKKYGSDRDYTYDELLTRVFEIMREKNPDMVAGEKKRFVMR PPQVLRVGTKXTSFANFSEICRLLHREPKHVLAFLLAELGTSGSIDGNNQLIIKGRFQQK QIETVVRKYIKEYVTCHTCRSPDTLLQKDTRLFFLQCESCGSRCSVASIKSGFQAVTVKR AAMRAK------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------DAHTAEVNCYXFNPYSEXIXATGSADKTVA XWDLRNLKLKYHSFESHKDEIFQVQWSPHNETILASSSTDRRLHIWDLSKIGEEQSAEDA EDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEEPETPAG ELEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----ILKKRKLKEMLRKKKRMLMFKRAE RYVKEYRQQARDEIRLRRMARKAGNFYVPDEPKVAFIMRIRGINGVHPRPRKVMQLFRLR QINNGVFIKVNKATLHMLKICEPYVTWGYPNLKSVRELIYKRGYGKIDKKRIPLNDNVLV EKKLGRFGIICMEDLIHEIFTAGKHFKQASNFLWPFKLSTPRGGWVRKYNHYNDGGDFGN REEKINGLLRKMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX---------------------------FMYDSFDNTYQPQIGIDSXXKPMYLEDRTI RLXLXDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFQQTSKWIDDVRTERGSDVIIM LVGNKTDLSEKRQVTTEEGERKAKELSVMFIETSAKAGYNVKQLFRRVAAALPGMEQETK KPMTEVKLKETPAE---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----PYVGIVTILMNDYPKLKYAVLVCLGLFVLIHRE-----------------GDSGV GKSCLLLRFADDTTTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYR GAHGIIVVYDVTDQESFNNVKQWLCEIDRYASENVNKLLVGNKCDQTTKKVVDFTTAKEY ADTLGIPFLETSAKNATNVEQAFMTMAAEIKNRMGPVTAAPNVKINSSTPVKQSSGGCC- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------LLARACAAQTKSTFLKLAGPQLVQMFIGDGA KLVRDAFALAKEKAPAIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQMDGFMPTSQ IKVIAATNRVDILDPALLRSGRLDRKIEFPHPNEEARARILQIHSRKMNVEGDVNYEELA RCTDDFNGAQLKAVCVEAGMIALRREAKELVHEDYMDAIIEVQAKKKTNLQYYA------ -----------------------RYADDXFTSAFVSTVGIDXKVKTVFRQDKRVKLQIWN TAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDNAQVVLVGNKC DLEEERVVSTERGKQLADQLGLEFFETSAKENINVKAVFERLVDIICEKMSESLDTDPTK GTRLTENPNPQNGSCQC------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------QGRNGSITQIPILTMPNDDITHPIPDLT GYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTREDHADVSNQLYACYAIG KDVQAMKAVVGEEALTPEDLLYLEFLTKFEKNFISQGHYENRTIFESLDIGWQLLRIFPK EMLKRIPAAMQAKYYPRE-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXX------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------DPIYALQAAMEGYEVATMDEACKIGRIFVTTTGCRDIICG RHFEQMPEDAIVCNIGHFDIEIDVKWLTENSIEKVEIKPQVDRYTLKNGRHLIVLAEGRL VNLGCAHGHPSFVMSNSFTNQTIAQIELWTK--EYSLGVHFLPKKLDEEVAALHLDHLGV KLTTLTDKQADYLGLSKKGPFKPEHYRY--------------PLSMLRRSDAEQLCVKVR SGAYIRGFCQAYDKHFNMAMIDVDETYRKPIFPKQNKKQI-------------------- -------MLCSNVENLSPQVIRQVAKELAELSSNPPEGVKVFPNEEDITDIQARIEGPAG TPYAGGIFKMKLVLGKNFPTEPPKGFFLTKIFHPNVANNGEICVNTLKKDWKPELGIKHI LLTVKCLLIVPNPESALNEEAGKLLLEQYDDYSTRARLYTEIHAKP-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------FHGLWKGLGPRIVMIGTLTALQWFIYD TVKVXFRLPRPPPPEMPESLKKKM------------------------------------ -----------IHVSIIAMSGLLHFNYNDIGVSRALLLLW---XXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------RPGIVSKEEDGQLSCKPILSRIL SLLAEQNDLQYAVPGGLIGVXTKMDPTLCRADRMVGHVLGAVKVLPEIYTELEISYFLLR RLLGVKTEGDKKGAKVQKLAKNETLMVNIGSLSTGGRVLAVRADLAKIVLTSPVCTEIGE KIALSRRVEKHWRLIGWGQIRRGLTVKP-------------------VITFLVGINRHYV TILLSSEKKSE-QQVADSHALIRSRXLRENGKYIPKHAFNMRKSFFNDEDRGFFVKNPMT DPTMMTDMLKGNVTNVLPMIIIGGWINWAFSGFLTTKVPFPLTLRFKPMLQRGIELLSLD ASWVSSISWYFLNVFGLRSMYTLILGQDNAADQTKVMQEQMSGSAMVAPPDPMKAFKAEW EALEICNHQWMLEGVEDEL-MFVLEWFTNILSFLGLYKKSGKLVFLGLDNAGKTTLLHML KDERMAQHVPTLHPTSEELSMGGMRFTTFDLGGHQQVRRVWKDYFPAVDGIVFLIDAFDK ERFNEAKAELDSLLTDEQVANAPILILGNKIDKPGASSEDEIRNCFGLHGQTTGKGPSPR YELRPMELFMCSILKRQGYGEGFRWMAQYI-XXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIPN IKFQSPDGEIFEVDVEISKQSVTIKTMLENVEEDEEALPLPNVNSAILKKVIPWCTYHRD DPPPPEGVGNKGKRTVALCSWDTEFPKVDQGTLFELILASNYFDIKGLLDVTCKTVANLI KGKAPVEIRKTFNLKNDFPPPEEGPVRKGNEWFEEKXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------DKVLFESTGRGKAKSVELEDVKFHQCVRLSRFEN DLTISFIPPDGEFELMSYRLTTHVKPLIWVESVIERHAHSRVEYMIKAKSQFKRRSTANN VEIIIPVPQDADSPKFKTTVGSCKYTPEVNAVIWTIKSFPGGKEYLMRAHFGLPSVIGED SEGKPPIQVKFEIPYFTVSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRT-XXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XX---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------SSLNFAFMKKCPLYMSTKNTILKRYDGRFKDISEEIYEADYPKKFDE LGIWYEHRLIDDMLAQALKSSGGYVWSCKNYDGDVQSDIVAQGYGSLGLMTSVLICPDGK TIESEAAHGTVTRHYREHQKGNPTSTNPIASIFAWTRGLEHRGKLDGNQDLVRFAQILEK ACVDTVDSGKMTKDLAGCIYGLKNVKPEHYLVTMDFLDAIAE---MGKLVSKIXGNKEMR ILMLGLDAAGKTTVLYKLKLGQSVTTIPTVGFNVETVTYKNVKFSVWDVGGQDKIRPLWR HYYTGTQGLIFVVDCADRDRIDEAKQELHRIINDREMRDAIILIFANKQDLPEAMKPHEI REKLGLTRIHDRNWYVQPSCATSGDGLYEGLTWLTSNYKSFGDLKVESGIKALNDYLAKR SYIEGYEPSQADSVVFSCLSGPDASMCHARRWYNHIKSYGAETAKFPGEKKDVNCYGDST CDDDADDDDIDLFGSESEKIRQQRLAEYAERKSPTLIAKSNIILDVKPWDDETDMGKLEE CVRSVETDGLLWGASKLLPVGYGIKKLQICCVVEDDKVGTDFLEEEITKFEDYIQSVDVA AFQKI------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --EIDVINSRTQGFCT-FSGDTGEIKTEVREQINAKVAEWREEGKAEIVPGVLFIDEVHM LDIECFSFLNRALESDMAPVLVMATNRGITRIRGTQYQSPHGIPIDLLDRLLIISTSPYE DKEIRQILKIRCEEEDVEMSDDALTVLTRIGMETSLRYAIQLITTASLVSRKRKSTEVDV DDIKRVYSLFLDESRSTQFLKEYQQAFMFNE----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------INNSCITNKQVLKDLVKVI QQESYTFRDPITEFVECLYVNFDFDGAQQKLRECETVLINDFFLTACLDDFIENARLLIF ETFCRIHECISINMLAEKLNMTPDEAEHWIVNLIRNARLDAKIDSKLGHVVMGTKAISPY QQVIEKTKNLDSRSNMLAVNIQKKLGLK-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXMPKYYCDYCDTYLTHDSPSVRKTHCNGRKHKENVRLYYQKWLE EQVQKLVDDTTAAFKAGKIASNPFQSGNAMIPPPTTLAVPPAAPAMSLMGPPPGAHLPPL RPPMGP-------------------------LLDILQKKGEIPNMAAXQKVXQSDFXQTV REVYEHVYETVDVSGTREARANATAKATVAAFAASEGHAHPRVIELPKTEEGLGFNVMGG REQNSPIYISRIIPDGVAAKEGGLKRGDQLLSVNGESVEGENHEKAVELLKNAVGSVRLV VRYTPKVLEEMEARFDKQRSARRR--------------IHFQEEFWRSKWVDSTYKGGDQ GKFVISAGKFYGDAEKDKGLQTSQDAKFYGISAKFDK-FNNENSPLVLQFTVKHEQNIDC GGGYAKLYSSDIDQKNLHGDSPYLIMFGPDICGPGTKKVHVIFNYKGKVLLTKKXIRCKD DVYTHLYTLIVKPDNTYEVRIDNEKVESGDLESDWDFLPSKKIKDPEAKKPENWDDRE-- ------------------------------------------------------------ -----------PRYSPDDSLYKYSDIGAVGFDLWQVKSGTIFDNLIVTDSVEEAEDHAKN TWVKTKAPEKKMKDKQEEEERKVREEEEKKMKDEEPDKEEEEDDXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------VSGCVQTILHCDSLYLIVTKVA RGKMITLPA--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ERVIRDVTXHDVDTANARPQGXQDIMSMMSTLMKPKKTEITDKLRKEINKVVNKYIDQGI AELVPGVLFIDEVHMLDIECFTYLHRALESSLSPIVIFATNRGKCTIRGTVDIASPHGIP LDLLDRVMIIRTLPYTQEEMVQILSIRSQTESIHITDESLQLLSEVGTKTTLRYAIQLLT PGNLLARINGKDXIGKEEIEEIGKLFHDAKSSAKILQKYEEKYMKXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-- ---------------------------------------------------------FPP GYPLSPPKMKFNSEIFHPNIYVDGRVCISILHAPGDDPMGYETSAERWSPVQSVEKILLS VVSMLAEPNDESAANVDAAKTWREDRQRFNDIARKTVQKSLGLMRIEKCYFCSGNMYPGR GMVFVRNDCKVFRFCRSKCHQSYKKKRNPRKVRWTKAFRKASGKDLTVDPVYEFEKRRNV PIKYSRELWTQTLGAMEKIAEIRQRREDHHIKCRLQKGKELRKEADVREVKQHIHLMKSP CAN--------------------------------------------------------- -------------------------RHWRLNERXYGAYQGLNKAETAQKYGEDQVKIWRR SYDVPPPALE-EXSRCASGQKAYADLDKKVIPKCECLKDTVARALPFWHDVIVPALRAGK KPIIAAHGNSLRAMVKYLDKMTDDEILNLNIPTGIPLVYELDANLNPIKHYYVADEAQVK AAMDKVANQGKAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------- ------THQYDXMKHAAATXAAGXC-VCCALPEXEDLNEWWLLTRLXFFNQINMLYGTIT EFCTEESCAVMSAGPKYEYHWADGQTVKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKI GVPFPKNFLSIAKTILKRLFRVYAHIYHQHFREVVQLSEEAHLNTSFKHFIFFVQEFNLI DRRELAPLQELIDKLTSKE-GYRYCHRFERKVRRTAPKSNDIYLRLLVKLYRFLARRTNS MFNKVVLKRLFMSRTNRPPIPLSRVVRHMKRHGREDKIAVVVGTVTDDIRMFDMPKMKIC ALRMTERARGRVLKSGGEILSFDQLAIKAPKGNNTILMQGRRKARKVYRHFGPAPGVPHS HTKPYVRSKGRKFERARGRRKSTGYKN--------------------------------- ------------------------------------------------------------ -----IKTLLAFFKSKFKVMVVEFHGQEMAKKLASANIETTLITDSAVFAIMSRVNKVII GTHTVLANGGLKVIGGHSIALAAKYYSVPLVVVAAMSKLSSHYLCSYDDAFNRFLSPSDI YNPAFDYVPPELVTLFISNIGGNAPSYVYRLLSELYHMIIPIRGFTCGKVIGNKWEAYLG LLQVEYTEGDALDALGLKRYCCRRMLLSHVDLIEKLLNYAPLEK---------------- ------------------------------------------------------------ -----------------------------------------EQQRLEEKERRHREEKARR MEQQKQVIIKEQETAEKIAAMAFAKSYLRDLVPTVFATLSDNGYFYDPVENDVEQGMIPW LMENVVIEVNRYNLSRRLMDAILWDVTKSRRKAY--MRARGELKEYKVIGRELPTEKCPK PPLFQMRIFASETCSAKSRFWYFASQLRKLKKTRGEIVCCHRIFERKPGTIKNYGIWLRY QSRSGIHNMYKEYRDLSAAGGVTQCYRDMGARHRARPSSIQIIRVETVVPKKCRRAYIKQ FHDAKIKFPLPHRVNKSLHNPRFTTRRPYTNF--------FWDKNKQRPISPLTI-XTSV DLCPSXAHRATGIAMSGAVTALAIAMLGLPHDFTYYVKLIQDLNLPASVIIGAKYIAVFP FMYHTANGIRHLAWDWATGFKLNTLYKTGYLTIVHL---TSSVALGSYRDQHFKGARSEQ EYYLLRSSTLYIGNLSFYTTEEQIHELFSRCGDVKRIVMGLDKVTKTPCGFCFVEYYDRA DAENAMRYVNGTRLDDRIIRTDWDVGFHEGRQYGRGKTGGQVRDEYRTDFDEGRGGYGKI ISSRM-------------------------------SSADKLVKMWGAYDGKCEKTISGH KLGIYDVAWCTDRRLLVSASDDKTLKMWELASGKCMKTLKGHSNYVFCCNFNPQSNLIVC GSFDESVRTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID DDNPPVSFVKFSXNGKYILAATLDNTLKLWDYSKGKCLKTYTGH---------NFSVTGG KWIVSGSEDNMVYXWNLQTKEIVQKLQGHTDVVLCCACHPTENIIASAALENDKTIKLWR SDVMIIYKDIITGDELFSDSYSDCYYEIEGKFDSMIGSNPSTDVNIVIAAKKQFMAFIKD YMKKLIAYEFYNGILLLNYSTPFFTVFKDSVVSEK--AVEFKDGVVIGADSRTTTGAYIA NRVSNKLTKVTDNIYCCRSGSAADTEAVSDIVHYHLSFYRMEMGEEPRVKVAAHIFKDLC YNYRDSITAGIIVAGWDKHEGGQVFSIPIGGMITRMPFALGGSGSTYLYGYVDSNYKPGM TKEECLKFTGNALALAMSRDGSSGGIVNMAVITKDGIEKILMVGDEIAKFXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------FMSKGSEQESMARLKKLMTIMDS----------- ----------------------NDQELDSLE--GERLFARSRCQRVARGAGVSVREVSEL LQQKFAQMVKKMGGIKGLFK-GGDINKNVFAQMTKLNHQMAKMMNPRILQQMGGMQGLQT MMRQFQQGAMSILTYNGSAIMAMKGKECVAIAADRRLGIQSLTVNTDFQKIFPMGPRLFI GLPGLATDVQTVSQRLKFRLNLYELRENRRIKPSTFNSMVSNLLYERRFGPYFVEPVIAG LDPITCEPFIASMDLIGCPMISNDFVVSGTCTEQMYGMCESLWEPDLEPGDLFETISQAL LNAVDRDALSGWGATVYVVEKDKVTKRTLKARMD-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------PKQVVTNSC LSKKLTLYXVKEEDLTYTAPFHLQCRRNDYIHALVCFFNIEFTKCHKRTGFSTAPESRYT HWKQTKEYLTVKKGEEIFGTFRMQPNKKNNRDLDFTVELDFKGELSEMSECLQYKMR--- --------------------------------------------------NTMIRKAIRX HLIRTPVLKVVAPHKKNNVVXCHPKNDLSEVRKXLKENKVKAPARAVPIAPCDVQVGAQN TGLGPEKTSFFQALSIPTKISRGTIEILNDVRLIKEGEKVGASEATLLNMLNISPFSYGL VIEQVYDSGTVFAPAVLDITDDDIRKKFMSGVANVASLSLAIGYPTMASAPHMLINGFKN LLAISLETKITFAEAEAVKDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXLMXEVNCSKQHEKGEKYDNMADLYAVINTXQSXEK LXIKDAVQPKEYTAACSKLLVQYKAAFKQVQSTSFPTVEDFMKKYRLDCPAALERIKEDR PITIKDDKGNTSKCIADIVSLFITIMDKLRLEIRAMDEIQPDLRELNETMTRLSLLPQNF EGKEKVSKWLTTLSGMQASEELNDSQVRQMIFDLESAYNAFNRVLHNXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTKSLPKTIGGEKNGETR KVRVSRLPRHLPTQVAKRKLQNPFSQHKRRLRASIRPGTVLILVAGRHRGKRVVFLKQLG TGLLLVTGPFALNGCPLRRVNQIYTIATKTRLKIKPVKIPSRINDDYFRRKSLKNLKHRE GELFDTAKEEYTLSNERKEDQLAVDKQILKVIKASKEKKSLKGYLETMFALKNKMYPHKM LFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXX------------------------------ARSQ RMREEFEKIAMRRSVEGVLIVHEHGLPHVILLQLGTTFFKLPGGELNPNEDQVDGLKRLL TETLGRQDGAPMDWIIEDTIGNWWRPNFEPPQYPYVPAHITKPKEHKRLFLVQLPEKALF AVPRNYKLVAAPLFELYDNAAGYGPIISSLPQALSRF-----MTPGGTTPTGQKAMAMAT PTPGHLMSMTPEQLQAYTWQRELDERNRPLSDDELDAMFPVGYKILQPPAGYLPIRTPAR KLMATPTPMAGTPMGFRMQVQIVDMQPKGNLPMMKPDDMQYFD----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------KLLVDVDEESLHPARKVRDVYWKVYNTVYIGAQDSMIPAYPRIPNDV KNQYIRYELDYML----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------RTTCLKYLVLANMLMKSGIN PFXSQETKPYKNDFEILAMTNLVSAYQNNDIDEFEKILQRNKQNIMEDPFIREHIEDLLR NIRTQVLIKLIKPYTRIHIPFISKELNIMPQEVESLLVSCILDHTINGRIDQVNKVLVLV TGVAQYNALDKWTSQLHSLHQTVINKMA-------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------FANAIDAEEILLFERATFLVISYWQRKPHRDVH RFEKISNIIKQFKLSCTKVAASFQSMEVRNSHFAAFVDAFTSNTYVMVIMSDSSITSAAT LLNIKNARQHFERLEKEE-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXX--------------------------------------- ------------------------------------------------------------ -----------------------------------------------IDQSIVKTSPITX VSGPEEIYIFRQIKFNTSSVIKIAVEPVNPSELPKMLDGLRKVNKSYPLLNTKVEESGEH IILGTGELYLDCVMHDLRKMYSEIDIKVADPVVSFCETVVETSSLKCFAETPNKKNKITM IAEPLEKGLAEDIENEVVQITWPRKRLGEFFQTKYDWDLLAARSIWAFGPDATGPNILVD DTLPSEVDKNLLVSVKDSIVQGFQWATREGPLCDEPIRNVKFKILDAVIAGEPIHRGGG- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------QDIFNLFDEKGDGKI SAYHLGEVLRAMGENPTQAEVKKCGREIERLSFEIVLPIMQTISRNKPLVTYDDLVEGFR VFDKDQNGIVSSAEMRHLLTGLGERLSPEEADQLLQGIEDNQGNINYEELIRIVM----- ------------------------------------------------------------ ----------------------------------------------------QRPISELI HKSHPLGSXEQMEAIHIASTPAELYNAVLVDTPLAPYFIDCISEQDLNEMNVEIIRNTLY KAYLEDFYSFCKEMGGATAEVMCEALAFEADRRAFVITINSFGTELTKDDRAKLYPRLGK LYPDGLSMLARADDYEQVRAVADYYAEYKELFEGVGINAGEKTLEDRFFEYEVRLMRNAF MQQFQYGVFYSYLKLKEQECRNIIWIAECVAQRHRAKIDSYIPIF--------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------RQE-CVXEMSPDHQHLXSGGNDNKLFVWNMTSVSPVQTYTEHLAA VKAIAWSPHQHGLLASGGGTADRCMRFWNTLTGQPLQCVDTGSQVCNLAWSKHSNELVST HGYSQNQILVWKYPGLVQIAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTR STKESKSVLNLFTRIRILIIVGLYYCLSGQGERFGIGWFLESSSPFMWAMIGIGLTISLS VVGAAWGIYTTGSSILGAGVKAPRIRTKNLISIIFCEAVAIYGIIMAIVIDNQNNYKAGY MMFGAGLTVGLCNLACGICV---------------------------------------- --------------------------------------------------RIYIESPAEY PFNPPKITLRTKIYHPNVDEKAQVCLPIISAENWKPATKTDQVIQSLVALVNDPEPEHPL RADLAEEFSKDKKKFMKNAEEYTKKFGEKRPADGASQTYPQQCSSLRKNGYVLMKGRPCK IVDMSTSKTGKHGHAKVHLVGIDLFNGKKYEDICPSTHNMEVPNVKRKDYTLLDVSDRIL ELMDDDGNLKSDLNLP-------------------GQLSYPWGIAWDNMGFIYVCEKENN RVQVFQANGNFVRKFGRSGPGTFNSPHYLAVSPDNXXYVTDSNNNRIQVFSYGDYLFSFG SEGIGRGHLCNPRGISIDDQGFVIVADCGNHRIQVFRGDGRFYSMFGFKSPEGVSVMTNG AVAVTDRENNRVQLF---MAAGPIAERNQDATVYVGGLDEKVTEAILWELFLQAGPVVNV HMPKDRVTQSHQGYGFIEFMGEEDADYAIKIMNMIKLYGKPIRVNKASAHQKNLDVGANI FIGNLEPEVDEKLLYDTFSAFGVILQTPKIMRDLDTGNSKGYAFINFASFEASDAAIEAM NGQYLCNRPITISYAFKKDNKGEKHGSAAERLLAAQNPLSLTDRPHQLFADAPPPPPQ-- -----------------------SFAPPP------------------------------- ------------------------KESGNPLFEKRPKNFGIGQDIQPKRDLTRFVKCPRY VKIQRQKAVLYQRLKVPPPINQFKQGLDKQLATQLFKLLDKYKPETKQAKKARLRARAER RAAGKEDVPTKRPPVVRAGCNTVTTLIQQKKAQLVVIAHDVDPIELVLYLPALCRKMGVP YCIVLGRVVRRRTCSSLAITQVNPEDRANLNKLVESVKTNFNDRFEEIRRHWGGGILGAK SQARLTKLERVRAKEIAQKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------Y RRIRLRFKNPNSNPDDWLTSDQLADVYKDFVKNYPVVSIEDPFDQDDWEAYTKMTCIQIV GDDLLVTNPKRVQKGIDLKAANALLLKVNQIGSVTESIEACKMSQNAGWGVMVSHRSGET EDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELGDKAVFAGKKFRNP--PPD AGAFRPRXSKATSXRRFYERGTF-LVLXIDTKGNKIAWKVEIEKMDYYHYFPLFFEGLRE TQHPYEFFARQGIHDMLEHGGNKILPCIPQLIIPIKEALNTRSLPVVCTTLKVLQHLVLS AEFVGEALVQYYRQILPIFNIFKNKNLNIGDEIDYSQQKRMNVGDLIQETLELFERHGGE DAFINIKYMIPTYESC-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--- -------------------------------------------------ESDRTLIYIPL YITECLKKLQRCTSKNAAQKEMYTLALKNYPIPGDSAFPLNALYAKPQKGTEEETMRQYL QQIRQETGLRMCDKVFDPETDKSSKWWLCFAKRKFMDKSLAAPG---------------- ----------------------------------------------------QERSRPVP RSYSRGTAGALMVYDITRRRTYNHLSTCFTDARNLTNXNTVIFLIGNKSDLEGQRDVTYE EAKQFAEENGLMFLECSAKTGENVEDAFLDTAKKIYQNIQDGSLDLNAAESGVQHKPSAP RNALNTDQAPSKEGCGCMSIKAVCVMKDGEVSGTIFFNQESDVKVMGEIKGLTDGKHGFH IHEFGDNTNGCTSAGGHFNPEKKEHGAPTDENRHVGDLGNVESSNVSIEDKLIKLTGVNS IIGRTVVVHADVDDLGKGDHELSKTTGNAGGRLACGVIGIAK------------------ ------------------------------SEAGEMRFTDTRXDEQERXITIKSTAISLY YELPKDDLNRAFLINLIDSPGHVDFSXEVTAALRVTDGALVVVDCVSGVCVQTETVLRQA IAERIKPVLFMNKMDLALLTLKLEKEEMYQTFRRVVENINVIIATYGGSDGPMGDVMVDP QKGNVGFGSGLHSWAFTLKNFAQMYSNKFKIPVPKLMKRLWGDNFFNCVRGFIQFILAPI YQVFETCMPHEEALALAEKMAIKITSDEKDLREKQLLKVMMRKWLPAGDALLQMIVIHLP SPVTAQKYRMEMLYEGPQDDAAAQAVKTCDPQGVLMMYISKMVPTTDKGRFYAFGRVFSG TVSTGQKVRIMGANYTPEKSIQRTMLMMGRYVEPIEDVPCGNICGLVGIDQYLVKTGTIT TFKEAHNMKVMKFSVSPVVRVAVEAKNPSDLPKLVEGLKRLAKSDPMVQCAIEESGEHIV AGAGELHLEICLKDLEEDHAQIPIKVSTPVVSYRESVREESDRPCLSKSPNKHNRLYMRA RPCPSGVAEAIDGGEITPRQDFKERAKNLADKYGFDVGEARKIWTFGPEGTGPNLLVDVT KGVQYLNEIKDSVVVGFQWASKESVLCEENMRGVRFDIHDVTLHTDAIHRGGGQIIPTAR -----------------------------------------AHCGEQMNAAGTPMCQVRA CLPENESNACTADVRXNNGGQAFPQ-VCDQWQELVVTEARKRKGLGDGVPPLDKVVDKLM LPLSLLRTAVNHPMLVELKNGETYNGHLVSCDNWMNINLREVICTSRDGDRFWRMPECYI RGSTIKYLRIPDEVIDMVKEEVVMKNKGRGEMKQRGRG--GRGTFGGRGGRGGGGGRGGG GGG--------------------------------------------------------- ------------------------------------------------------------ IWDPRSPCSPGVLPNQTKXYTLAVCGDRLVVGTAXEKVLVWDLRNIGYVQQRRESSLKFQ TRCIRCFPNKQGYVLSSIEGRVAVEYLDPSPEIQKRKYAFKCHRIKENGVEKIFPVNSIA FHNSHNTFATGGSDGFVNIWDGFNKKRLCQFHKYPTSITSLAFSHDGSTLAIASSYMYEF DVPEDAVFIRNVTDQETKPK---------------------------------------- ------------------------------------------------------------ ------------------------------------------DVIIPRHRFMAAYEQKVE PPDRKWQYLLXAAEPYETIAFKVPSREVDKDPKKXWTYWNKETKQFFXQFAFKLDQKAIP PPPQRMPPPPPVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------ ------------------------------------------------------------ ---------QHDTKFYPFKVINKNNKPYVQAMVSGEMKTFAPEEISAMVLGKMREIAEAY LGKDIKNAVVTVPAYFNDAQRQATKDAGLIAGLNVMRIINEPTAAAIAYGLDKREGE--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------------PC VLIQVYEGESPMTKDTNLLGKFDLTGIPPXPRGVPQSEVAFDIDANGILNVSATDKSTXK ENKITITNDKGRLSKEEIERMVNDADKYRQEDDEQRSRVTAKNALESYAFNTKSTVED-D KVKEKISEEDKKTIVDKCQEVISWLDQNQLASKDEFEHQQKELEKVCNPIITKLYQAMP- ----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXPKIGINGFGRIGRLVLRCALMKASVVAINDPFVDLNYMVYMFKYDSTHGL FKGEVTLIVNGVQIAVFNEKDPSNIPWGSVGAEYVLESTGVFTTTEKASAHLKGGAKKVV ISAPSADAPMFVVGVNHQNYTKDLKVVSNASCTTNCLAPVAKVVHEKFGILEGLMTTVHA YTATQKCVDGISAKDWRGGXTAGTTSXPSSTGAAKAVXKXIPELNGKLTGMAFRVSTXDV SVVDLTVRLXXXTTYXDIKNAVE-KMKGVLGYTEDAVVS--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------PEVMPK LTRESESTLRKAFEDAEKNPPPITLIDEIMVLPQRGKSQHGDVERRIVSQMLTLMDGMKQ RSHDGVMAATNRPNSVDPALRRIARFDKEVDINVPDATGRLEILRIHTKNMKLANDVDLE QIAQETHGHVGADLASPCSEAALQQIRGKMDLIDLDDETIDAGVLDSLAVTMEDFRWALG KSNPSALRETSVEVPSVSWDDIGGLEHVKRELQELVQYPVEHPDKFVKFGLT-------- ------------------------------------------------------------ -----------------------INQLLTEMDGMNAKKNVFIIGATNRPDIIDTAILRPG RLDQLIYIPLPDDKSRVQILKATLRKSPVAKDVDVDFLAKKTNGYSGADLTEICQRACKL AIRQSIEAEIRLEKERNQNPDDVDPVPEIRRDHFEEAMKFARRSVNENDVRKYEMFGKTL QQSRGFGNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX-------------------------------------------------VWKVRVDL PEKYPXKSPSIGFMNRIFHPNIDEVSGTVCLDVINQAWTALYDLSNIFESFLPQLLNYPN PIDPLNGDAAAMYLHKPEEYKKKVQEYVKKYATEEALREQESSMSDFSEDEVQDMEL--- ------------------------------------------------------------ ---------------------------------------------------DLVKMLVGN KIDKERREVSKEEGLKFARKHRMLFIEASAKTKEGVQYAFEELVEKIIQTPGLWETDGLR LSE--------------------------------------------------------- ----------------------------------VITWPRYIRQKCXERLIKIRQYLQRI RKITLRGKRKLVPLQRKVERREKRREEKALVAAQLDNAIEKQLLERLKSGAYNDIYNFPV HAFNKVVEGEEVEKEDDQTPDVEYIPYEDFEESDIEDLE--------------------- ------------------------------------------------------------ --LSXVSKIDDNLSKQTKIYPLPHMYVIKDLVPDMNNFYAQYASIEPYLKRKDLKEEDIG KEQIYQSVEDRSKLDGLYECILCACCSTSCPSYWWNSDKYLGPAVLMQAYRWMIDSRDDF TTERLSMMEDKFSVYRCHTIMNCTKTCPKHLNPGLAIGQIKKMLALY------------- ---------------------------------------------QQIVLQQLQQQQQQQ QQQQQQPVMQNPT--------------------------------------AANTIPEQP PNQILFLTNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENEMQAGAAKDALQ GFKITPNNAMKITFAKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------- -------------------APPKVRSPH-KILHTGXAILMLY-LGWIDPEGIFPVILGHE GAGIVESIGENVTSVKPGDHVIPLYVPQCRECKFCKNPKTNLCQKIRVTQGKGVMPDGTS RFKCQGKDIFHFMGCSSFSEYTVVAEISVAKVDMKAPLEKVCLLGCGISTGYGAALNTAK VEKDSICAIWGLGAVGLAVAMGCKTAGASRVIGIDINNSKFEVAKKFGVNEFINPKEHDK TIQQVLCEMTDGGCDFTFECIGNVATMRAALESCHKGWGVSTIIGVAAAGQEISTRPFQL VTGRVWKGTAFGGYKSRDSVPQLVLDYMSGKLLIDEFITHNMEMEKINEAFDLMHQGKS- ------------------------------------------------------------ ----------------------NDMERIWQYXYSKDQLQTFAEEHPVLLTEAPLNPRRNR EKAAXIFXETFNVPALYISMQAVLSLYATGRTTGLVLDAGDGVTHAVPIYEGFAMPHSIM RVDVAGRDVTRYLRLLLKKEGYDFHTSAELEVVKAIKEKICYLPLNPMKEEGVETEKVAY TLPDGNTIEIGPARFRAPELLFKPDQIGEECEGIHECLVYSIRKSDLDLRKVLYSNIVLS GGSTLFKGFGDRLLTEVKKLAPKDLRIRISAPQERLYSTWIGGSILASLDTFKKMWVSKR EYNEEGVKAVHRKMF--------------------------------------------- ----------------------------------MSKKVMHGKK-CGWYHTGPKXHQNDV SINELMRKYCPNSVLXVIDAKPKDLGLPTEAYIAVEEVHDDGTPTTKTFEHVSSEIGAEE AEEVGVEHLLRDIKDTTVGTLSQRITNQLMGLKGLHSHIDDVNRYLEKVASGQLPVNHQI IYHLQDVFNLLPDVNLQDFVKAVYVKTNDQHLVVYLAALIRCIIALHNLINNKIQNRDAE KSEGKDKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXKEIPTKRILISDPSQMPMDYSTTPGGSIFSTTPGG------------------- ----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------VRANTLIAEARGLDVSKVSVPVIVGHSGVTIFPL ISQTTPPVSFPXEERERLSRRIQNAGTEVVEAKAGAGSATLSMAYAGARFTFSMLEALSG MEGKVECAFVRSDETEVKYFSTPLLLGPNGVEKNLGIGKLIEYEVQLIKEALPELEANIK KGEDFV------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------HAIPSRMTIGHLIECLQGKVAANKGEIGDATPFNDSVNVQKVSNLLQQ YGYHLRGNEILYNGHTGRKLNAQVFLGPTYYQRLKHMVDDKIHSRARGPLQIMNRQPMEG RSRDGGLRFGEMERDCQIAHGAAQFLRERLFEVSDPYRVHVCNLCGLVCIANLRNQTFEC RGCKNKTQISQMRMPYACKLLFQELMSMSIAPRMMV------------------------ ------------------------ADTRATDDTVVADKNCAKIHYILTNIYCCXAGTAAD TEKITQMISSQLELHKLNTGRTPRVVTANCLLKQMLFKYHGMISAALVLGGVDPTGPHLY SIWPHGSTDKLPYVTMGSGSLAAMAVFEDRYKPNMSREEAMALVRDAIAGGIFNDLGSGS NIDLCVLTKKVDYVRPFDECNQKGKRTGSYKYARGTTSVLTTEVTKVPFTIV-------- -LTSDPKQPYKVLSVPEKAPFTAVLKSAAEEFKVPAATSALITMDGIGINPAQTASNVFI KHGSELRLIPRDRVGH-------------------------------------------- ------------------------------ILLNAPLIAYHVRRYMNRPYMSAHGLYDPT TIMNADELSRAMREGWVKLAFYLLSFFYYLYSMIYVLVSSMGLLTILKKMKQKEKEMRIL MLGLDNAGKTTVLKKFNGEDIDTISPTLGFNIKTLEHLGYKLNIWDVGGQKSLRSYWRNY FESTDGLIWVVDSADRMRLQDCKQELDALLLEERLAGATLLVFANKQDLPGALKAEEIKD ALELSXIKTHHWLILNCSAVSGENLLQGMDWLIDDIASRIFTMD---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------WTHELPIALN XEIANELPYNDYFEYYGPDFKLHISPSNMANQNTAEYLEKIKSRLYENLRMLPHAPGVQM QAIPDDAVNEDENPDERISIRASDKRIVRDEELSDSEDEG-EGRRERMNYKPKAK----- QCILCLEPRKDTIATPCGHLFCWNCIHEWCQSKNE---CPLCREKFTTSRLI-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------AIDGIVNIFDTTTGRSLEGHAMPIRSLCFSPDSQLLVTGSDDSHIKI YDVQHANLVGTLSGHGSWVLTVDFNPDNVHFVSGSSDRKVKIWDATTRQCVHTFGEHSDQ VWCAKYNPEGNKVVSVSDDKSVYIYDCPLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXX------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------VHMRGLPFQAIEQDIRDFLXPLDPIRIEFE Y-RNRPTGEADVDLLHXQEAVSGMELHKNYIQDRYIELF--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------QIVLEEADRS IHDALCVIRCLVKKKALIAGGGAPEIDLALRLMQVASSLTGMEQYCFRAFAEAMEVIPFT LAENAGLNPVSTVTELRNRHAHGEKNTGINVRKGAITNILEENVVQPLLVSQSAVYLAAE TVRSIMKIDDVLTCV--------------------------------------------- ---------------------------------------------YNISLVYDENIPEDY VEXCEEGSLLKRNCXASVFEKYFQFQANHKRAVIHYRDEETMYVDAQKDRVTVIFSTVFK DDSDVVIGK--------------------------------------------------- HQNKDNTINLIHTLRDYSHYHIKCSKAYIHSRMRAKTSDLXKVLNRARPEPKAVEKKTMX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------- --------------------------------------KISGLRGRGGAGFPTGMKWXFM NKPSDGRPKYLVVNADEGEPGTCKDREIMRCDPHKLVEGCLIGGRAMGARAAYIYIRGEF YNEASSLQIAINEAYEAGFIGKNACGSGYDFDVFIHRGAGAYICGEETALIESLEGKQGK PRLKPPFPADVGVFGCPTTVSNVETVAVAPAICRRGGEWFASFGRDRNR----------- -----------------------------------------------------RFVTGNG RPEEIDMLYEITKQIEGHTICALGDGAAWPVQGLIRHFRPLIEERMAEY----------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------HSRNEGVATYAAAVLFRMSEDKPHDFRKRLSVELTSSLFRGD QMSADLQWMIIRKNNSFLIKRNWLSKEPNNLKGRHSFRFNGLIHKKTVGIEPCKDGKGIV FVTRKKGRHPSATFNRVDMKKDPRRTLTAIRKTLSKTRYRRDLKMAAMRKASAVIRSQRP LVKKAGR----YCSQQIDIPPDLPDIMKQFTKAAIRTQPKDVLECANAYFTALYKGEEPP VKERYEMPMATQKTDTGLTIGLLKILNKQLSSRKDVTPLEIEEKWNNLSLPKEQLDELLK LGDLRGLFQWEKFLALAASALAESIQTAIKNICDILTDDPEGGASRIKIDKFEFFYNYLA TIDGEIPPSYVTEVLKHFKSVANNHDGYIQPSFF---------XXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXX----------------------------------------------------- ------------------------------------------IQSLKDTKTTVDAMKGGV KEXKKAYKHVKIDDIEDLQDELEDLTEQAGEIQEIMGRSYGMPEIDDSELEAELDALGEE IGLDEDTSYLDDAVTTPSVPTSEPGADSM--KDSVPVDEFGLPQI---XXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- ------------------------------------EKMCHRPHRHQ-VYYCSWKGSALV TKNMXCWRFVYGEKKIVVEEGNKIEYRAWNPFRSKLAAAILGGIDNIHMKPGSKVLYLGA ASGTTVSHVSDLVGPEGLVYAVEFSHRSGRDLLNVATKRTNIVPIIEDARHPLKYRMLVG MVDTIFADVAQPDQARIVALNAHHFLKNNGFVVISIKANCIDSTAEPEAVFAGEVAKLRL EKIKPLEQLTLEPYERDHAVVVGCYRAPPKK----------------------------- ------------------------------------------------------------ --------------------SRPDAFSLPTMYRQMGXXYDERVXPSICNEVLKSXVAKFN ASQLITQRQQVSMLIRRQLRERAQDFHIILDDVSITDLSFGREYTAAVEAKQVAQQEAQR AQFIVERAKQERQQKIIQAEGEAEAAKMIGESVSINPGYLKLRKIRAAQSISKTISNSQN RVFLDANSLMLNIMDPLFGDSAE------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------SVLKTKXDNLYSCRE SIXDALKRTTDVMXGGKQVLICVXGEVGKXCAQALKGMGCVVMVTEIDPICALQACMDGF RVVKLNEVVRQIDILITCTGXKNVVTREHLDRLKNGCIVCNIGHSNTEIDVGSLRTQELT WEKVRSQVDHIIWPDGKRIVLLAEGRLVNLSCSSVPSFVVSITASTQALALIELYNAPAG RYKDDVYLLPKKMDEYVASLHLPTFDAHLTELTDEQAKYLGLNKAGPFKPNYYRYPDPDA IKMFVGQIPRSMDENELRKMFEEFGPVFQLNVLRDKMTGQSKGCCFVTFYTRKSALDAQN ALHNIKTLPQMHHPIQMKPADSEKRNVEERKLFVGMISKKFNESDIRILFSNYGSIEDCT VLRDQNGQSKGCAFVTFNNRQSAQNAIK-------------------------------- ------------------------------------------------------------ --------------------------------------------------KLFKEGGIRS VYKGTGATLLRDMPASGMYFMSYEWMQNMLTPKGGNRNELSARTLVAGGTAGIFNWLVAI PPDVLKSRYQTKEEGILAMYRGVTPVMLRAFPANAACFLGYEVTIKALN----------- ------------------------------------------------------------ ----------------------------------------IEEDTALILEREERIQQLEG DILDVNEIFRELGVMVSEQGDQIDSIEANIETARVEGGYEQLKKAETYQKRSRKKMCLLL LFLIIIVAVIVIII-----MVNVLKGVLVECDPAMKQFLLQLDDKNTLGKKFVINDLDDT HMFISADIVETLKTQINDLM------------KXPSPQEAIDKLRSIEEMLMKKSDXLES KIQTELETAKKRGALLALKRKKRFEKQLQQIDGTLSTIELQREALDNASTNTEVLNVMGA SAKAIKAAHNNMDIDKVHDLMDDVAEQQEIANEISEAISNPVGFGQDIDEDELLQELEEL EQEELERDLLNVGQLPSVPLAEDTDLSELAAWA--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----VSPADNXQVKEIRCIVIPHSXGTHQRVHLPNTLPDHEYLQEMEPLGWVHTQPNELP QLSPQDITTHAKVMSDNSSWDGEKTVIITCSFTPGSCSLTAYKLTPSGYDWGRQNTDTGN NPKGYLPSHYEKVQMLLSDRFLGFFMVPSQSSWNYNFMGVRHDPNMKYDLQLANPKEFYH EVHRPSHFLNFSAMEDGADREDLY------------------------------------ ------------------------------------------------------------ -------------------EKKLTEQSTTRLIGPNCXGIXXLGECKIGIMPXHIHQPGTI GIVSRSGTLTYEAVHQTTLVGLGQTLCVGIGGDPFNGTDFIDCLEVFIRDPKTKGIVLIG EIGGNAEENAAEYLKKXNGADAKPVVSFIAGLTAPPGRRMGHAGAIIAGGKGGANEKIEA LREAGVHVTASPAQMGSTMVKAMQ-------ESLKCTICNQRLEDTHFVQCPSVPEHKFC FPCSRESIKDQGAGNEVYCPSKNKCPLVGSLVPWAFMQNEIATILG-RKFVEVGRVAYIV SGTYSGRLCAITDVIDQNKALVIGPLTGVPLRAINFKSLHLTRFVLFRHSAKSQEVKTAW ERKAISRRWAQTKWAKKIECRKKKAQMTDFDRYKLMRAKQSRNKIIRLQVGKLRKKPLKT CPLLLRVFCNTGRHHPLNEYLRGQTPSNELQIYTWMDATLKELTGLVKEVNPDARRKGTY FDFAMVYPDLRQQMYRLQEIGTTCSGHRGADDNVTLASKKFTIGDYLDIAISPPRXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------------------- ------------EGKDVKIIKSTEWETKRLTKSIAKRKQWKKXESAENDPPGPNSANTIE EITMTFINNKDASDENPLQKLKVSCRICKGDHWTTRCPYKDTLQPLQENLSKTGKYVPPS LRDGANKRGESMNNDEFATIRVTNLSEDTRESDLQELFRPFGTIHRIYLAKDKNTGQSKG FAFINFHRREDAARAIAGVSGYGYDHLILNV----------------------------- -LHQFIENKFKQDSNHTIGVEFGSKVVNVGGKSVKLQIWDTAGQERFRSVTRSYYRGAAG ALLVYDITSRETYNALTNWLTDARTLASPNIVIILVGNKKDLEADREVTFLEASRFAQEN ELMFLETSALTGENVEETFLKCARSILTKIESGELDPERMGSGIQYGDASLRRLQTRRPD CAC--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------AQIMLPGVXRXEDGIELNEEXV IVTTKGEAICLAIALMTTSVMTTCNHGTVAKIKRVIMERDTYPRKWGLGPKANVKKLMIS KGLLNKFGTPNEKTPQKWLEMLIKLQAPKKRKREPESDDQKKKKKKKKMAEADWSGKR-A KAGQLRSKQAVTTAQRSGASIETTKRYSAGQNKQHAANINANKLDLETEELHINKVSLDV SRLISQIRQQRNMTQKELATKINEKQQVINEYESGKAVPNQQILGKLERALGVKLRGKER GQPLAKK----------------------------------------------------- ----------------------------------NLLLCIYAKETVEFGMLKAKLQALAN YLEGPLQRLAAS------------------------------------------------ --------------------------------------------------------EFIE ERRHGLESFINRVAGHPLAQNERSLHMFSXEPVIDKNYVPGKIRTT-------------- ------------------------------------------------------------ ---------------------------------AHEDILPYSSNERHPIHHELLTKFLMH DPAFIARDTLRAWQEKNHPWLQLSDVHREITENIRVTVIPFYIGESQQTNVFWWRYCVRL ENLGDDTVQLRERHWRIFSLSGTLETVRGRGVVGQEPILSNEQPAFQYSSHVSLQAPSGH MWGTYKMERRDGTSFECRIPPFSLESKSDDAXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ICIPCRAYTHEVVTLWYRAPEVLLGQARYTAALDMWSIG CIFAEMVMKRPLFHGDSEIDQIFRIFKILSTPNEECWPGVTSLPDYKTLFPKWRKNNLAK SVDESGLDLLRDLFIYNPSNRISAKKALRHEYF--------------------------- ------------------------------------------------------------ ------------------------------------------------------REVVSQ RVSEELIERASTFGLLLDDISLTHLTFGKEFTEAVELKQVAQQDAEKARYLVEKAEQIRQ AAVTTAEGDSIAAKVLSQAFVDAGEGLIELRKLEAAEDIAQQLARSRNVLYLPKGQQTLL NLPMKTIKADQLIKIPKGVSVRVKSREVEVTGPRGKLNRSFRHLFITITHPSPNFIKVEK QFGKRKELAAVRTVCSHIENMIKGVTKGFSYKMRSVYAHFPINVVILEQGQAVEIRNFLG EKYVRHVDMLPGVVFSVSPAQKDEFILEGNDIELVSRSAALIQQSTSVKEKDIRKFLDGI YVSEKGTV---------------------------------------------------- ----------XXSQEECYQYRPGVDSNIMQSMNAIIRAMDXXKITCGCPESENDARTLXD ISMNTDESDMTPDMAAXYKRLWADSSVVSCVARSREYQLNDSAQYYLNSXDRISMPNYIP SEQDVLRTRVKTTGIVETHFTXKDVHFKMFDVGGQRSERKKWIHCFEGVTAIIFIVAMSE YDLMLAEDQEMNRMMESMKLFDSICNNKWFSDTSIILFLNKKDLFEEKIKKSPLTTCFSE YEGANTYEEAAAYIQVQFNKRKDSKEIYTHFTCATDTNNVQFVFDVVTDVIIKNNLKDCG LFQKXASMKRMISLKDARIKHDQR-KKIPKKIDKSKITLRDAPQTSSALFFTYNTQLGPP YRILLDTNFIHFSVKNKVDIITGLMDCLYAKCIPYVTDCVMGELEKLGVKYRVSLKVIKD SRFERLACLHKGTYADDCLVQHVTQHKCYIVGTCDKDLKRRIRKIPGVPIMFLRNKGYSI ERMPDAFGAPK------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------ILASASFDSTVRLWDVEQGNCIHTLPNHQEPVYSVAFS PXGKFLASGSFDKCVHIWNVQTGSLVHSYRGTGGIFEVCWNFRGDKVGASASDGSVFVLD LRKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XX-------XQRKMDQRSHDQMRPTFLRAGVISQAKGSAYSELNKTKVICAVYGPREI-- TRRESMKGQLTCEFKFATFSCQLRRQH-QADNQEKDLAIQLLEALEPAVCLHKFPKAQVN VYATVLENDGSALAAAITCASVALAYAGIEMYDLVLSTSVRLAGDVVLLDPSANEEFKPG SLTVGYMPSLNQISALTSSGECELEVLTKAMKLCIESCQKV----------XXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXPSQVRFAHTDIQVPDFSAYRRESVKESRKAFTYLLSVGGSVTGIYAAKT VVHEFVSSMSASADVLALAKIEVKLGDIPEGKNVTFKWRGKPLFVRHRTSEEIETERAVD VSSLRDPQHDDDRCQKPEWLVLLGVCTHLGCVPVSNIGDFGGYYCPCHGSHYDAAGRIRK GPAPLNLEVPPYIFKDETTLVVGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXX-DVKEFLARAKEEFQQKWDHPSHNTACLDDFDRIKTL GTGSFGRVMLVHTRXIKXYYAMKILXQTKVVXLKQVXHTLNEKRIYKQFLXPFX------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------KSRNLEKQREAGMDVAD RSQKKKLNGQEEKLKNNSRDXSLVKMKSMFAIGFAFTALLSMFNSIFDGRVVAKLPFTPI SLMQGLSHRNLGGDDYTHCSFIFLYILCTMSIRQNIQKMLGLAPSRVASKQGVGFFSPXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXX-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------RMEKRHNYVRKVAEVAVQLFITNDKP NISGLVLAGSADFKTELSQSDMFDPRLQAKIIKIVDVSYGGENGFNQAIELASDALANVK FIQEKKLIGRYFDEISQDTGKYCFGVDDTLKALEMGAVDILIVWENLDITRYILKNHSTD EEKILHLRPEQEKRK--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------FGHKXAQRIGHGEDKHSDADRSPVFLQFID CXWQMTNQFPIAFEFNEHFLITIMDHLYSCLFGTFLYNTEQQRVKEDVKPKTVSLWSFIN SNMEDFLNPLYQHVLLPVASLRQIELWMGYYCRWNPRLRPQEPIHLRNKELLFLKSQLQR KYEELKKE---------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------------TTIPPNLKX MDPELHLDGKIMQGHLAAIRHARWFEENASHSSIKVLIRLIRDLKNRFQGLEPLTPWIVD LLAHYAIMNNPSRQPLPINVAFRRCLQLLAAGFFLPGSVGITDPCEQGTVRVHTVMTLEQ QDQVCFTAQTLLRVLSHGGFRQILGLEGNSSIATEMSVWEGVVVTPSDKAYEKPEK---- ------------------------------------------------------------ ----------------------VLRQTDXMIMLKQTQPDRYVHLENMLARSYXDPREAYL EGQTKEKKRSAIAQALSGEVNVVPPSRLLALLGQALKWQQHQGLLPPGTTIDVFRGKAAV REQEEEKYPTQLSKTIKFGQKAHVECSRFSPDGQFLVTGSVDGFIEVWNFSTGKIRKDLR YQAQDNFMMMDDAVLCMCFSRDSEMLATGSQDGKIKVWKLLTGQCLRKFERAHAKGVTCV TFSRDNGQLLSASFDQSIRVHGLKSGKTLKEFHG-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------LFFQEATLVTAEIACWFFIGEIIGKGSLIGYNIPGA-------- ------------------------------------------------------------ -----------------------------------------MQFFNYVMRK-XVASNRIX LSLYDVTGLVISRXNRXGKYILELIPTLPRLNVXERSFYSFYVCTAVRKXFFFLDPMRTG KIKILDILACSFLDDLLELRDEELSREMQESNWFSAPSALRVYGQYLNLDRDHNGMLSKE ELARYGTGTLTDVFLDRVFQECLTYDGEMDYKTYLDFVLALENRKEPQALQYLFRILDVE QKGFLSVFSLNYFYRAIQEQMRRHNQDPISFEDVKDEIFDMVKPKDPLKITLQDLITSGK GDTVLSILIDLNDFWTYENRE--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----LDQLNHILSVLGSPSPEDLQCIINVKARGYIQVLPYKPRIPWCNLADPKALDLLDR MLTFNPNKRITVEQALAHPYLEQYYDPDDEPVTEKPFTFETELDDLPKERLKSLIFDETV RLKQ-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ IPXPLGTITILCIDLGTDMXPAISLAYEQAESDIMKRQPRDPVNDKLVNERLISMAYGQI GMIQASAGFFTYFVIMAENGFWISRLLGIRKNWDSMGVNDLEDSYGQEWTYAQRKKLEYT CHTAFFVSIVVVQWADLIICKTRRLSLFQQGMKNHRLTFGIIFETVLAAFLTYCPGLDQG LRMQPLRASWWFPAFPYSLLIFIYDECRKLILRRHPGGWVESETYY-------------- ------------------------------SVFDHASIRRAIKLXNKCCXACHSMRYLCY RXFGGVSHTEDEARVEAEEVMVVDGPDDDGNMYERPGKLSDRFPKPYANDEAARAANNGA LPPDLTYITSARHGGEDYIFSILCGYCDAPAGVTIQEGTYYNPYFAGGAIGMAQALYNEI IEYDDGTPATQSQLAMDVVTFLKWAAEPEHDQRKKMALKALVIFLISLSYYYKRHKWSVL KSRKIA------------------------------------------------------ ------------------------------------------------------------ -----------------KIDMLKLLGVELFPVPA-VALTDPNHYNQQARRYAESLENSVW TDQFDNLANRLAHLETTGPEIWRETNGKVDAVTFSTGTGGTFSGVSIYLKEQNPQIQSFV ADPPGSVVYNWFERSEGETEGIGQGRITGNMQGAPVDDAFHVTDKETMEMVFRLLGEEGF FVGASSGLNVAAAVQAAKKLGPGH--TIVTCLCDTGQRYYAKLFSEAELKKR-------- ------------------------------------------------------------ ------------FIYPDDQKYEGQWIDDLRY-VGTYHYVNGDTYEGEWKNHVRHGQGVYT YADTKSKYVGKWANGKMSGPGELIHSNHKYIGMFRNNYPNGIGKYMFNIGCEQHGVY-MA DIMKLITRDLSEPYSIYTYRYFIHNWPKLCFLCMDSRKCVGAIVCKLDIHKRVIRRGYIA MLAVDAEYRRRKIGSNLVLKAIRAMLTDGCDEVVLETEITNKAALKLYENLGFVRDKRLF RYYLNGVDALRLKLWLR--------------------------------ISEAPXQKTNL AVTDSKGHILYSKQDAKKGKFAFTTDEYDVXEVCFDNKLVAGGHGADREVTLIMKHGVEA MSYEDLAKAEKLKPLEVELRRLEDLSKSIVDDFAYMRAREEEMRDTNESTHSRVMYFSIF SMCCLLGLATWQVLYLRRYFKSKKLIE-----------------HRKCVNKPEHGNLXWI KXCEQSHKVITFIDLADIEKYLKTTVCXMTGHAPDFAMLMVGANAGVIGMTKEHLGLALA LNVPVFVVVTKIDMCPPNVMQDTMKLLQRLLKSPGCRKIPVQVQNSDDVVCTATNFTSER MCPIFQVSNVTGENLDLLKMFLNLLSTRHKSEPAEFQIDDTFSVPGVGTVVSGTLLRGLI KLNDTIMLGPDSLGQFQSIVIKSIHRKRMPVKEVRGGQTASFALKKSSIRKGMVMVSPXL EPKACWEFEGEILVL--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------RIHKLTVTNAEVSSTQFNWD CSLIXSGSMDKSCKIXDTASGQCIATLKDHEDEVLDVCFDYTGQYLLTASSDNVYDVPTH RKLEGHVGEISKVTFNPQGTAILTASSDKTARIWDPESGVCKQVLEGHTDEIFSCAFNYD GNIIITGSKDNSCRIWRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXX-------------------------------------------------------- ------------------------------------------------------------ --------------------------------------------------ARQQIQSELQ DKNMPMGIDIDQYNLSHTSPNIRYKPDPLRYXKSSTTPQQWEDYTRYNVDRAQAELKGSR ILRETILHTQHQTKNDLEAQHNATEYAFRKRMHDFERAIDELEWQKKNTEEEIAEMDNDI RALNDAIANKRFHMKQVQTRLENRTYRPNVELCRDAPQIGLTDEVKQLDATVMALKEKLR QSQHALDGLQKNLHHINDELDCKMHSLMLDRRCMDVRQRLERNLTMTGI----------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TSXVPFDPDKDWTWNLHPMLGFEDPAFTELMRLYLTIHSDHEGGNVSAHTTHLIGSA LSDPYLSFAGGMNGLAGPLHGLANQEVLVWLTKFQVTDDQLREFIWATLKSGQVVPGYGH AVLRKTDPRYTCQRDFALKHLPNDPMFKLVSQLYKVVPDTLMQHGKAKNPWPNVDAHSGV LLQYYNLTEMNYYTVLFGVSRALGCLASLIWDRALGLPLERPKSFDVKHLKKMV------ ---DKCGICQKTVYPQEKVEAGGIKFHKLCFKCSECKMSLNLNNYAQADGILYCKKHYQD IVVAKNTQ---LFVHRDSPHNNSKDVLXVTPENMTRAEAIIANYPEAHKRAAVIPLLDLA QRQIGWTPISAMHTVAKMLGMPKMRVYEVATFYTMFNREPVGKNFVQICTTTPCMLGGVG SDVIFDALKKKLGIGNGETTPDKMFTLLEVECLGACVNAPMVQINDDYYEDLTVEDINRI IDDIIAGKKPKPGPQSGQGHRFSCEPKGGLTCLTDKPTGPGFGVRSDL------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------VLXGAKLYSTSIDMWSAGCIX AELANAGRPLFPGNDVDDQLKRIFKLLGTPTEDTWPGVTQLPDYRTYPIYHVSPQVVPKL NSKGRDLLQRLLVCNPSQRLCSEEGMQHSYFADLSPAIK--------------------- -----PVEYCELYPNCDRCKLWLEKILPAQLQMMARKRQTRGGNGVLKAKKITEPQGLKL STATRGKKKRVTFIDGLATYDIDLKVAGKFFATKFYCGSSVTG-DEIVIQGDVKDDLFDI IPEKWPQIDEDSIDDLGEQKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXX------------------------------------- ------------------------------------------------------------ -----------------------------GLAARCADTQERSAQFAKWRCVLKIGPHTPS YQAMMENANVLARYAMICQQNGLVPIVEPEVLPDGEHDLATSQKVTEQVLAFTYKALADH HIFLEGTLLKPNMCTAGQACTAKFTPEQNALATVTALRRSVPAAVPGITFLSGGQSEEDA TINLNAINNKPWALSFSFGRALQASVLKAWQGKDENIKKAQEQLLIRAKANGLASVGKYG GSSDSAASESLYIKNHAY------------------------------------------ ------------------------------------------------------------ -----MXQEYDEXILKHXMDISVXLXNGFTLEFYFEPNDFFNNSVXTKQYIMKSEIDEND PFSFEGHEIIKCCGCEIEWKKGKDVTTKVVKKKLKHKGRGTTKTVTKTVENDSFFNFFNP PTPPADELDEDTEDILAEDFEVGDFIRERIIPRAVLYFTGEALDDRG------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------LGRCDAFEEEQIGGERYNCSPXCPQAKTCTLIL RGGAEQFIEETERSLHDAIMIVRRTLKNYTVVAGGGAIEMELSRYLRDYSRTIAGKDQLL IGAMAKALEIIPRQLCDNAGFDATNILNKLRQKHSGMWFGVDVTKEDITDNFEACIWEPA VVKCNAIMSATEATCLLLSVDETIRNPKSENPSEGGARGRGRP----------HFHKDWQ RYVRTWFDQPMRKKRRAKRRLIRARKVAPRPAKGLLRPIITCPSIKYNARVRAGRGFTLE ELKKAGINKREAPTIGIAVDFRRRSMSAEALQRNAQRLKEYRSKLILFPRKLSKPGKKDS PPEELKLATQLKGTLLPIVNKMKKDKPRKVTRDMRKFKAYYTIATARADKRCFGRRQRR- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------QCIDISIMLAEA IRRTHNGESVSYLFFHVPL----------------------------------------- ------------------------------------------------------------ ---------------------QLTELYMKTACYCDEKSKKPGASYDAFKLAVTNPNILDE CDIDANTKKVLLENIHRRLTPQAVKIRADIEVACYKYEGVDAVKAALTKGLELSTEDMPI KINLIAPPLYVMTTQTLERIEGMARGQQKIQSQQKKAQKMEKLKHDQKKAAAAALNYKCK VCMSLMPDVKTYKQHFENKHPKATLPEELND----------------------------- ------------------------------------------------------------ --------------------------------------------------------QPIN DSYISALNRHCXPECFVCWDCQRPFGNMSFFDHDGLPYCEQHYHAKRGSLCADCQQPITG PSIIAMGRKFHPKHFTCAFCLKQLNNVTFKEQNNKPYCHPCFSKLFMRPLTDEECKVFFE KLSKYIGENIKQLLERPDGKYCFRFHKDRVYYSKENLMKKAGHISRENLLGFGTCFGKFT KSGKFRLHITALDFLAPYAKYKIWLKPNAEQQFLYGNHVMKAGLGRITEATQQFQGVVVY SMSDLPLGFGVAAKSTQECRHADPMATIAFHQADIGEYLRNEERI--------------- ------------------------------------------------------------ ------------LGHSERRNXFGETDELIGEKIEHAISEGLIVIACIGEKLEEREAGKTE DVVFAQTKTKDWSKVVIAYEPVWAIGTGKTATPEQAQAVHESLRKFLIDNVSKEVADNVR ILYGGSVSASNCNELATKPDIDGFLVGGASLKPDFVKIVNA------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------DIANAWKAW -KLQRKFXGMVLSEXQRLERLDHLAQKFRHKCSIHEEWXTAXDGMLNA-PLQKCSLQEMK ALKKKHEAXESDLAAHQDRVEQIAAIAQELNALNYHDVASVNSRCQLICDNWDVLGTLTQ KRRQELEQAERVLERIDQLHLEFAKRAAPFNNWMDGAKEDLMDMFIVHTTEEIKDLIQAH EQFKETLGEADKEMNTIVSLENEANRLAAEIGI-GVPENPYTALLVSHLTHKWSEVKSLV PQRQDVLQQE-------------------------------------------------- ------------------------------------------------------------ ---------GISEDQMNEFRMSFNHFDKGRTRRLEPKEFKACLVSLGYKIRDDKQGEVDF QRIMSIVDPNSSGYVSFDAFLDFMTRETADTDTAEQVMQSFKILAGDKNYITAQILRHEL PPEQAEYCIQRMAPYSGGDAVAGALDYMSFSTALYGESDL-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------WLKVIKKMEIGSSLFDEDGSKI VEGLIEKAKSKNVELVLPVDFVTGDKFAENATVGQATVSGGIPAGHMGLDVGPESSKKFA EVIAKAKTIVWNGPPGVFEFDNFAQGTKSMMDAVVKATQSGTISIIGGGDTATCCAKFNT EDKVSHVSTGGGASLELLEGKVLPGVAALTDAXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRLKTQIPDIKTCL DIVKHLQSIKESFETQFLLSDLLYAKAKIPPTDKVFLWLGANVMLEYSLNDAQTLLEKNM ANTSLVQVEEDLGFFRDQTTTLEVNMARVYNWDVKRRQSNKE------------------ ------------------CNEFTYKIESFHKIVTSLIEVVDNVSKEVEKEKMKAIGSRNL LMSATKQREEEQIQLMALIREKKMQMERLRIQHEALLKQERDQNDFIEQFML--RSRSXD RSSREKXHRRSPSRSPMELFLEERDARTIXCMQLXARIXPRDLEEFFSSIGKVRDVRLIT DNKTRRFKGIAYVEFVDVECVNKALALTGQRLLGVPIMVQPSQAEKNRAAGNSGPMRLYV GSXHFNITEEMLRGIFEPFGKIDDIKLIKDHEXGRLQGYGFITFHDXEDXKKALEQLNGF ELAGR------------------------------------------------------- -----------------FMLANMFDPSSSKINWDQEIRDDVIEECNKHGGVVHIYVDKAA VQGNVYVKCPNIAAAVASVNALHGRYFAGKLITAAYVPLPNYHTLFPGAIRANQLLLPS- DERDDEVSPTPPHHIPKRTRRGGVSAEVYKEEDAALYVKKVVPKDYKTMAALSKAIAKNV LFSHLDDNERSDIFDAMFPVHRHAGEVIIQQGDDGDNFYVIDQGEVDVYVNNEHVTTIGE GGSFGELALIYGIPRAATVKAKNDVKLWGIDRDSYRRILMGSTI---------------- ---------------------DGQQIVRQGEPGEDFFIITEGTAAVLQRRADNEEPIEVG RLGPSDYFGEIALLLDRPRAATVVARGPLKCVKLDRARFERVLGPCSDILKRNISQYNSY VSLSV------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------IKDNLLLDNFLAPHVQPLYMLIRKKALS QYFRPYLSVDMHDMAEAFNTNVKDLEDELMQLILEGQINARIDSHNKVVYTKNIDQRSST YEKALTFLHEYQRKTLGVILRAAFAKRHLLV----------------------------- ------------------LPHVARSCLIAPFXEDGIRMWNQWSEQRDYMNSTWNCGGFLA SMFVLFNLVGQLGGCVMVLSRQRVPTACAILFGIITLQTIAYSILWDLKFLLRNLALAGG VLLLLAESKAEGRSLFAGLPSLGEDNPKQYMQLSGRILLVLMFLTLLRFDLNLFQIIENL VGTGLILLVAVGYKTKLSAMVLVVWLTALNLYFNAWWNIPDYRPMRDFLKYDFFQTLSVV GGLLLVVAYGPGGVSMDEHKKKW------------------------------------- ------------------------------------------------------------ EYSGLEHESTRGVXESLKIITRDNSLRIAKFAFDYAMKNNRKKVTAIHKANIMKLADGLF LECCKEVAAMYPDIELDSMIVDNCCMQLVSKPDQFDVMVLPNLYGNIVDNLSAGLVGGAG VVPGGSFGHNVAMFEPGARHPFAEALGRNIANPTAILLSACYMLHHIHLDFHADAISTAV LKVINDGKIRTPDMGGYSTTTDLTMAVIDNLXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXX--------------------EKIENMDEDDFHAIQKKRLEDL KKXHKLRKEWMELGHXEYSEVANEREFFDECKKSKNVVCHFYRESTFRCKIVDKHFQILA PKHLEAKFIKLNVEKCPFLVERLNIRILPTIYVAVNNKSVCHIRGFTELGNTDEFSTEML EWRLGQTKVINYDGEMIAGPGGPKSTKTIRQNSDEE------------------------ ------------------------------------------------------------ ----------YVYKIPEGIXFHDAAAIAMNYLTAYIILFDIGNLRSGQSILAHSIGGGVG QAIIQLTKTVENVTLYGTASAKHESLKPN-VTHLFDH-GVDYAQEIRKLSPEGVDIVLDC LCGDYTNKGISLLRPMGRYILFGTSSVVTGETKSFFSFAKSWWQVDKISPLKLYDDNKFL AGFQLRQLLLMDKLFKLYTDGTIKPVIDQVASFEDIAEAMQRLHDRXNIGKIILDXXIXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX------------QLNELMKNPVEGFSAGLIDD-DIYRWEVXII VPPDTLFEEGLFKAHLVFPKEYPLRPPKMTFKSEIWHPNIDKDGNVCISILHE------- -----------HXVETILVSVISMLADPNDESPANVEAAKMWREHPDEFKRKVGKCVRKS QE-------PLLRSTLYDFGEYVGSCLPKYVQQVQLTYNNELEVLIHPEGIIPVMTFLKD HHNAQYLNIVDIAGVDIPCRTYRFEIIYILLSLRYNSRIRVKTYTDELTPIDSICSVFAG ANWYEREIWDMYGVFFSNHPDLRRILTDYGFDGHPFRKDFPLSGYTEVRYDDEAQRVVIE PLELTQEFRKFEYSTPWETFRGFRTK---------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------RDPMPRYM-TQMQCFSA RFLLSKVXPSQTHNNA--GCGAPVLTDDVSLQVFMEHLKKLAVSSSSXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------SKGPRKHIIQVSTFQMCVLMLFNT HGKITYEEIKSETDIPEKDLLRAIQSLAVGKIAQRVLHKDPKTKEIEPDHVFTVNDQFTS KLFRVKIQTVAGKGEAEPERKETRSKVDEDRKHEIEAAIVRIMKARKKLQHNVLVAEVTE QLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKMYTYLAXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXX------------------------------------- ----------------------------------------------VGAMPRREXMERKD LLAANVKISKXQGKPLNEHAKKTAKVLSLXNPANTNALICMKNAPSIPPENFSALTRLDQ NRAQYQIAARQDVKNVIIWGNHSSTQFPDVTHATVVKEAIADDVYLKEDFLKTVQQRGAA VIKARKMSSAMSAAKAICDHVRDWWNGVPDGSFVSMAVCSDGYGIEKGLIYSFPVRTDHS YQIVQGLSIDDFARGKMDATMQELQEERDMALGVC------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------RQINSYLG------------ ------------------------------------------------------------ ------------------------------------RHGGSVQVVSSTNGELAPLIDHSN TPITVPNDVEVVDETKCC------------------------------------------ ------------------------------------------------------------ -----LFVRVSNKVPVDMYNKLGYTVYRRVXEYYSGQDDEDAFDMRKALSRDKDKKSVIP LPHPVRPEEL-------------------------------------------------- ----------------DFYRSPWSNMYDPPLEDGTVPSDRLRKLEINANAAFDQYREMYF EGGVSSVYLWDLDHGFAGVVLIKKAGDGSKKIKGCWDSIHVMEVQEKSSGKTAHYKLTST VMLWLLTTKEGSGTMNLGGSLTRQIEMDAPVGESSPHIVNIGKMIEDMENKIRNTLNEIY FGKTRDIVNGLRSVMPLQADALRNDLVMALQKR--XXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXX---------------------------------- ----------------------PEIVRHRIRDTYLYFGGSVAATAISRSPAMLNIMMRNS WMAIGASFAAMIGSGMLVRSLPYKEGTKQMAWMLHSGVVGAVIAPLCFLGGPILVRAAWY TVGVVGGLSTLAMCAPSEKFLNMGGPLAAGLGVVFVSSIGGMFFPPTSALGAGLYSISIY GGLVLFSMFLLYDTQKIIRNAEHHPVYAARPYDPINNSIGIYMDTVNIFIRIATILSGGS SRRRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXX-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------SSTVX GKPMTITRTHTEIDVDGTSELIANAKNIIIVPGYGLCVAKAQYPIAEMVDLLKKKGKNVR FGIHPVAGRMPGQLNVLLAEAGVPYDVVLEMDEINDDFGETDLVLVIGANDTVNSAAEDD PNSIIAGMPVLRVWKSDQVIVMKRSLGVGYAAVDNPIFFKENTSMLLGDAKKTCDALL-- --MPIPTNVSNCPPGLEYLTAIDQLIVDQQVELIEALTNIECANKYKIVNSQNQQVYMAT EESELCERICCKNGRGFMMHIWDNYGREVIKVTRPFQFCAGCCWCADCSLYIEIEAPVGQ VVGRVQQTCMAAHYDVQNSVLKIRGPTCVLDGPCCTGDQDFNIFTQNIGKISKKWSGFVR EMFTNADKFGMSFPLDLDIKTKATLFGALFLIDFMFFE----XXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXX---------------------FHDRLSTVIEEFKKFC TKAKSKRERLCYYLGGLEMSATNILKLLAKPVTWDMPAAKICEKLKKADSQICELKYEKT IDLAKTNLKKLKVKDLKKLLSQWGEACKGCAEKSDFIKVIEDLMPIYAPEA-XXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX--------------------------------------------- ------------XDSQKHAHKLXYDPDDXXYXRRP-GVEKQYRQKCKRCGXWLYYHHQSN VMFIVEDALRKAGEVKTDVYSQISKPKKVTLTKHTKNMGKFSSVTVSTVDEEEEEIEAKE IADSYAANALVIEKQLLRKGMSKRKLMEQAEEEAKK-RPKGTLIDXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------- ----------------------------HGFEDFKRVLMVNTAGTFNVIRLAVGLIGKNQ PNADGHRGIVVNTASVAAYDGQMGQVAYSASKGAIVGMTLPLARDLASQGIRCMTIAPGL YDTPLLAGLPEKVRKYLAATVPFPSRLGYPEEYAQLVQSIIENPMLNGEVIRIDGALR-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------GLYASGESACASVHGAIXXGAN SLLDXXVXGRACANTIAEENKPGDPIGQISQNAGEESVANLDRLRYANGSISTAELRLKM QKAMQNHAAVFREGHTLKKGCEVMSEIYSQLDLKISDRGLVWNTDLIESLELQNLMINGM QTIYSAENRKESRGAHAREDFQTRIDEYDYSRPLEGQVKKPI-EHWRKHTISDIDIKTGK VSLTYRPVIDDTLDMQDCPYVVPAVRSY-----EEDVLRRTRKAIRDLNTLRNEHNSLIN NIQIASKDNNALDKDFRDERLNILKHSQEAIDLAGEEHPTTLTVQDELARILIRTNRRQ- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------EALKMLRSIVSVKYAMYGDYSVPVAETLTLMAALHLAD GELERALKSYEKCLEIRRLMLGEKHPKTIDVQRNIDILRAN------------------- ------------------------------------------------------------ -------------------------------------------------------QTVNL SKGRNMPMVXATIXQCXTEAQRXGFSRTCLWPXNPKKHVVSFTDEQXRAGELQAGTNKCA SQKIGGVRHIADIRADDLDKTGNAVISLQAGNKFASQKGMSFGAVRHVSDIRCDDMEQNA QGHIGLQSGTNQCASQKGMGFGAVRHISDIRADVMDKDGQSVIGLQAGSNKGASQKGMVI GAVRHVADIRADDHVEAEGVLSLQAGTNKFASQKGMSFGAVRHIADIRADDMQSEG---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------WVHDVSFSPSGDKLAWVGHNSSISVVNATLKTNFLPFVSCTWLNESSILG VGYDCCPLLFAYSDQQLRFMCNLDIGTQSAMQRFRDLDRMAVNVKTLHQNTITQAIVYSG TKENCSKFSTSGVDGNLIIWDFKKELENYVGFANLPNQVYRKSVKRGFEFNLMVVGESGL GKSTLINSLFLTDLYSSEYPGPSLR----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------FNLHEDMACSVAGITSD ANVLTNELRLIAQRYLLQYGEPMPCEQLVSALCDIKQSYTQFGGKRPFGVSILYMGWDKH YGFQLYQSDPSGNYGGWKATCIGNNSASAVSMLKQEYKEGETNLEEALRLAIKVLSKTLD MTKLTSEKVEIAKLTREDGKTKIEILSADYVEKSIKKHEEEEDKTEADKKK--------- --------------------------------------------------------KHEV LNEISSIGGEVTSLETEAKRLEEIHADQAPQIEVKQREIEENWQSLRGKAAERKSRLDDS NNLHRFLADFRDLISWIHDMRAIISADELAKDVAGAEALLESHHEHKGEIDARADSFKST TEAGTHLVQSGHYAADDVKEKLQELAVERNNLLELWEERRIMYEQCMDLQLFYRDTEQAD TWMTKQEAFLANEDLGDSLDSVEALIKKHDDFEKSLAAQEEKIKALDEFASKLIESEHYA HEDVAARRDQLLDRRNKL------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------LEPYKNXQDPLSAVSQKX DDALCLQQFXRDXXDEETDXREKDPXAAXTNRXRDXIGVQSLIKKHQXLLAELTGHESRI TNVCQLGQGMXGEGHXAAEEIQQKTQELEEKWTGXKDKANQRKQDLDDSLQAQQYFADAN EGESWMREKEPIAANTDYGKDEDSAEALLKKHEAFFADLEAYRTVIEGLREQALACKQQE APVIDDLGSEKVMALYDYTEKSPREVSMKKGDVLVLLNSANKEWWKVEVNDRQGFVPAAY VKKLDPSLSASRNNLMDEFTISVRQNQIETQYANLIDL---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----EPYKNXQDPLSAVSQKXDDALCLQQFXRDXXDEETDXREKDPXAAXTNRXRDXIG VQSLIKKHQXLLAELTGHESRITNVCQLGQGMXGEGHXAAEEIQQKTQELEEKWTGXKDK ANQRKQDLDDSLQAQQYFADANEG------------------------------------ ------------------------------------------------------------ ----------ESWMREKEPIAANTDYGKDEDSAEALLKKHEAFFADLEAYR----TVIEG LREQALACKQQEAPVIDDL----------------------------------------- -----------------------GSEKVMALYDYTEKSPREVSMKKGDVLVLL------- --------------------------------NSANKEWWKVEVND--RQGFVPAA---- ----------------------YVKKLDPSLSASRNNL---------------------- ------------MDEFTISVRQNIETQ--------------------------------- ------------------------------------------------------------ -------------------------YANL------------------------------- ------IDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX X----------------------------------------------------------- --------------------------------------------FPTDGFHAAATNNLCI ATGVRGGVDWMRKLAFRYRRIKEIYNSYRNNVGGLLGPQKREQWLQLRQEIENMTDSWLT MALKSLNIINSRSNCVNVLVTTTQLVPALAKVLLYGLGGVFSIENIYSATKIGKESCFER IVSRFGRKCTYVVVGDGRDEEAAAKQMNWPFWRISNHSDLAALHHALELSYL-------- ------------------------------------------------------------ ------------------------------------------------------------ ----------TEXLDSECIVNAAKTSMSSKLIGAEADFFSKMVVDAIMAVKVTDSKGNSR YPVKVVNVLKAHGRSSKESILVNGYALNCTIASRAMPRIIVGAKIACLDFGLRKEKMKLG VQLLIEDPEKLENMRKRESDITKERIEKILATGANVILVSGGIDDLCLKYFVEAKAMAVR RCKQVDLKRIAKATGGMHIH--------------------------------MLIKGPKV HSAASIILRGANDYMCDEMERSVHDAMCVXKRVLESKSVVPGGGAVVAALSIYLENFATS LGSREQLAIAEFAHSLLVIPKQLAVNAAQDSTELVAKLRAYHNMAQTKPEHLDLKWIGLD LHEGTVRDNKKAGVLEPAMSKIKALKFATEAAITILRIDDMIKLNPEQKERDPHDDCC-- ---AEKTARLLFTKNVMNQYLVEGKDIVIEYKIYNVGDSAATDVKLKEEGFPETEFKIVQ GFLAVQWDRIAPKTNVSHAIVMKPLKYGFVNFTAAELTYLPKEDERLVGYTSAPGKSGII NQKDFERRFSPHVLDWLVFAIMTLPSLGIPYMLWYSSKRKYDTIKPKRN----------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TEGRMTGSVDQIASIVHFETHEALPNWDKQIQSLCVQVNLIIERISEKEPD WMIKY------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -TFTGHTNNKGIPLEASFSPDSKXVFSGSTDGKIHXWSTETXSKVAMLSADHPGPVQCVQ FNPKYMMLATACTNMAFWLPYVDE------------------------------------ -------------------GKGKTFAAGADIKEMKDQESXNVVKTNFLGHWDGITKARKP VIAAVNGYALGGGCELAMMCDIIYASDRAKFGQPEILLGTIPGAGGTQRLTRAVGKSKAM ELILTGNMITAAEAEKXGLVSKITSSDELMTATMETAEKIASQSKLVTAMCKEAINAAYE MSLTEGCHFEKRLFHATFATHDRKEGMTAFVEKRPPKFTD >Eurythoe_complanata MTDRKAVIKNADMSEEMQQDAVDCATQALEKYNIEKDIAAFIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX- ------------------------------------------------------------ ---------------------------------IVKQITSISIEPGVEVEVTIAD----- -----AKNFSKDSLRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNII V----------------------------------------------------------- ---------LTSVVQKRFNFPEGTVELYAEKVATRGLCAIAQCESLRYKLIGGLAVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGEPTNDYVDTAVRHVLLRQ GVLGIKVKIMLPWDPAGKIGPKRPLPDHV----------------------MSKRGRGGA SGGKFRISLALPVGAVINCADNTGAKNLYIIAVHGIGGRLNRLPAAGSGDMVMATVKKGK PELRKKVMPAVVIRQRKAIR---------------------------ITGPVAKECADLW PRIASNASSIRKGKVQKVSLGPQTVEGENVFGVAHIYASFNDTFVHVTDLSGKETICRVT GGMKVKADRDEASPYAAMLAAQDVAEKCKTLGITALHIKLRATGGNKTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL-------------------------- ------------NLIAGASHAKGIVLEKIGVEAKQPNSAIRKCVRVQLIKNGKKITXFVP RDGCLNFIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANTSLLALYKEKK-------- ----------------KQMVVDVLHPGRATVPKTEIREKLARMYKTTPDVIFCFGFRTQF GGGKIIGFALIYDSLDFAKKFEPKYRLGRHXTRKQRKERKNRQKKVRGIKKAKVG----- ---------------------------------NKREVWRVKYTLANIRKAARELLTLDE KDPRRLFEGNALLRRLVRIGVLDEGKMKLDYVLGLRLDDFLERRLQTQVFKLGLAKSIHH ARVLIRQRHI-------------------------------------------------- ---------ILKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVCEAREELMRMLAEDELRD CHLLVFANKQDLPNAMNAAEITDKLGLHSLRNRNWYIQATCATSGDGLYEGLDWLSTQLK TSKMPLAKDLLHPSLDQERRKCKLKRLVQSPISYFMDVKCPGCYKITTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRRK-----------------------------RPCSKV IVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVALRDLESWTTRL LPSRQFGYLVLTTSGGIMDHEEARRKHLGGKIL-------------GISQSALPYRRSVP TWLKLTSEDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKAKGLAPD IPEDLYHLIKKAVAIRKHLERNRKDKDSKFRLILVESRIHRLARYYKSKKVLPPNWKYES ATASALVAVTELPEIKLFGRWSSEDVQVNDISLNDYIAVKDKYAKYLPHSGGRYQVKRFR KAQCPIVERLTCSLMMHGRNNGKKLLTMRIVKHAFEIMHLLTGENPLQVVVNAVINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREASFRNIKSIAECLADELINAAK GSSNSYAIKKKDELERVAKSNR-------------------------------------- ------------------------------------------------------------ ---GHTKDVLSVAFSADNRQIVSGSRDKSIKLWNTLGVCKYTIEDCHTEWVSCVRFXPNT QNPIIVSCGWDKLVKVWNLTNCKLKTNHIGHTSYLNCVTVSPDGSLCASGGKDGQAMLWD LNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEGKIVVDELRQEVISTSAQ PPQCVSLAWSADGQTLFAGYTDNLIRVWQVSVAGRMREYKLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKQVEVDCNQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKMARHFNCAFLETSAKSK INVNEIFYDLVRQINKKNPEQ-------ASEHISLKVTGQDGSVVHFKIKKNTPLRKLMT AYCDRTGVKMGAMRFIFDGNPISETDTPAGLEMDNEDTIDVFQQQTGG------------ --LTGKPVMVKLKWGMEYKGYLVSVDGYMNLQLANTEEYIDGAFSGNLGEILIRCNNVLY IRGVEEEDEEGEMKD--------------------------------------------- -------------------------------AEHGINLFKVDDNKKLGEWAGLCKIDREG KARKVVXCSCVVVK--------------------------------DGACGKTCLLIVFS KDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSI DSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRTDELTKRELMKMKQEPVRPEEGKS MSEKINAFSYLECSAKTKEGVREVFETATRAALQVKKKKKGGMDDFQSAEETAFVVDEVS NIIKEGIEGAIGGNAYQHNKVNQWTSNVVEQCLNQLTKLGKPFKYIVTCVIMQKNGAGLH TASSCFWDNSTDGSCTVRWENKTMYCIVSVFGLAI------------GEKPDEFESSISQ ALLELEMNSDLKAQLRELYITAAKEIDVQGKKAIIIFVPVPQLRAYQKIQTRLVRELEKK FSGKHVVFIAQRRILPKPT-------------SRTLTAVHDNILEDLCYPAEIVGKRIRI KLDGSRLIKVHLDKNQQTNIEHKLDTFTAVYKKLTGKDVNFEFPD---GRGGFRGGFGGR GRGRGRGRGRGKEGDKDWIPVTKLGRLVKDLKIKSLEDIYLFSLPIKEFEIIDFFLGTAL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDFAGHVGLGVKCSKEVATAIRGAIILAKLSV VPVRRGYWGNKIGKPHTVPCKVTGKCGSVIVRLILAPRGTGIVSAPVPKKLLHMAGIEDC YTSARGQTATLGNFAKATYAAIAQTYSYLTPDLWKETQFTKSPYQEFTDYLAK------- --LKEEDVSKFLSCGTHLGSTNVDFQMESYVYKRKPDGVYIINLRKTWEKLLLAARAIAA IENPADVCVISARPYGQRAVLKFASATGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDP RTDHQPVTEASYVNIPVIALTNTDSPLRYVDIAIPCNNKGAHSIGLMWWLLAREVLRLRG TISREVPWEVMVDLYFYRDPEEAEKEPEVADWAS---------TTEDWAATEPQDWSAGT T-NEWGG-----------------------------------------------PIRKDD EVQVVRGXYKSQQVGKVVQVYRKKFVIHIERIQREKANGASVHVGIHPSKIVIIKLKMDK DRKRILERKARSRDKGKHTEESI--------------------------MWRFYTEDSPG IKVGPVPVLVMSLLFIASVFMLHIWGKYTRGKREGKKKSAINDVVTREYTVNIHKRIHGI GFKRRAPRAIKEIRKFAEKMMGTPDVRVDTRLNKHMWSKGIRNVPYRVRVRLARKR---- ---------------------------------FIINGKYRLVRKIGSGSFGDIYLGMNI QNGEEVAVKLESHKARHPQLLYESKLYKILQGGVGIPHIRWYGEKDYNVLVMDLLGPSLE DLFNFCSRRFTMKTVLMLADQMIGRIEYVHNKNFIHRDIKPDNFLMGIGRHCNKVFLIDF GLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRSS LPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLR QLFRILFRTLNHQYDYTFDWTMLKQKACAG------------------------------ ------------VNNIPGIEEVNMIKEDGQVIHFNNPKVQASLAANTFAITGHAETKQIT EMLPGILNQLGAESLSNLKKLATATEDIDEDDDDVP------------------------ ----------------NTRETAHAIKKMHLRRAVRFLKNVSAHKECVPFRRYNGGVGRCA QAKNWKATQGRWPQKSAEFLLQLLKNAESNAEYKGLDTDHLVIEHIQVNKAPKMRRRTYR AHGRINPYMSSPCHIEVILAEREQAIARPAKKKVSQKKLKRQKMKMRDKKTGPKPELTEE QKQEIREAFDLFDAEGTGTIDAKELKVAMRALGFEPKKEEIKKMIQEIDKENTGTIDFND FLTMMTKKMSEKDSKEEILKAFRLFDDDGTGKISFKNLKRVAKELGENITDEELQEADRD GDGEINEQEFLRIMKKTSLY---------------------------------------- -------------------------------------IIDTMYNASNNELVRTKTLVKNS IIHIDATPFRQWYEAHYTLPXGRKKGATLTDQDKAVLEKRSKKRQKKYDERKKLSKVEPA LEEQFTTGR--------------------------------------------------- ------------------------------------------------------------ -------------QKDVKDGKFTQVMSNVLDNKLREDLERLKKIRAHRGLRHFWGLRVRG QQT------------------------------------------------------KKA RKAMSKLGLKQVAQVSRVTIRKSKNILFVINRPDXYKSPASDTYIVFGEAKIEDLSQQAQ MYIKVLLQIEEEIDEAGVEGKDIELVMSQANVSRPKAVKALKNNNNDIVNAIM------- -----------------------NKRICEEIAIIPSKKLRNKIAGFVTHLMKRIQRGPVR GISIKL----RERRDNYVPEISAIEEVDPDTKEMLKMLDFGNIP-----------MKWEY KEEHAFEKRRAEGEKIRKKYPDRVPVIVEKAPKARVGDLDKKKYLVPSDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGALYQEHHEEDFFLYIAYSDESVYGMRDLRIVKL CLNICVGESGDRLTRAAKVLEQLTGQQPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAE EILERGLKVREYELRRGNFSDTGNFGFGIQEHL--------------------------- -------------KHRVNKEESMKWFQQKYDGVIMPGKMGIKFLEFVRPFCAVLPEIAKP ERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGIS PIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMVITVGQAIVYVMTGMYGDPAD IGAGVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVN TGRGTEFEGAIIALFHLLATRQDKVRGLREAFYRQNLPNLMNLMSTIFVFAIVIYFQGFR VDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAAKFSGNFFVNLLG VWADVGGGGPARSYPVGGLCYYLSPPETLTHVVEDPIHACLYIVFMLGSCAFFSKTWIEV SGSSAKDVAKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIG SGTGILLAVTIIYQYFEIFVKEQSEMGGMSTLLF-------------------------- ------KTPREAIDGTYIDKKCPFTGNVSIRGRILSGVVLKMKMQRTIVIRRDYLHYVRK YNRFEKRHRNMSVHLSPCFRDGDXGDVVTVGE---------------------------- ------QRFSPCPRKEEVRHTLHKVTQYKKGRDSLHVQGKRRYDRKQSGYGGQTKPIFYK KAKTTRKIVLK------------------------------------------------- ---------------------------KGVVRDIIHDPGRGAPLAKVVFRDPYRYKLKTE TFVAAEGMYTGQFLYCGKKANLQIGNILPVGSMPEGTIVCCMEEKTGDRGRLARASGNYA TVISHNPDAKRTRVKLPSGTKKVIPSANRAMVGIVAGGGRIDKPMLKAGRAYFKYKAKRN CWPKVR------------------------------------------------------ ----------------------------LEVSQHGKYTCSFCGKETMKRRAVGIWSCKSC RKTVAGGAWVYSTTAAATVRSAVRRLREVKEMGRRPARCYRYCKNKPYPKSRFCRGVPDS KIRIFDLGRKKARVDEFALCVHLVSDEYEQLSSEALEAGRICANKYLVKHCGKDAFHLRM RPHPFHVVRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQPIMSVRAREGHKEHVL EALRRAKFKXPGRQKIFVSRKWGFTK---------------------------------- -----------RTGSQGQCTQVRVEFLDDSNRSIIRNVKGPVREGDILTLLESEREARRL R-TKGTSSFGKRHNKTHTICRRCGRSAYHIQKKTCARCGYPSQRIRKYNWSIKAKRRKTT GTGRMRHMKSVFRRFRNGFREGTVPKPKRKMVDDRAAAKELDQWVEQLMECKQLTENQVR TLCEKAKEILTKESNVQDVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDR GYYSVETVTLLVALKVRFKDRITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHSNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRC GNQAAIMELDDALKYSFLQFDPAPRRGEPHVTRRTPDYFL-------------------- ------------------------------------------------------------ --KPTNQGVNQLKFQRGLQSVAEERVGRRCRALRVLNSYWVAEDSTYKFYEIIMVDPFHK AVRRDPNYQWICKPTAKHREMRGLTSAGRKSRGLGKGHKFHMTTGGSRRANWKRRNSLQV RRKR------------------------------------------------TPWESGLY KLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSLLDEEKDWRPAVTIKQILLGIQE LLNEPNIKDPAQAEAYTFYCQNKIEYERRVREQAMRFRNPAMGKSSKMLQHINYRMRCTL QDGRIFIGTFKAFDKHMNLILGDCDEFRKVKPKTSKQREEKRVLGLVLLRGENLVSMTVE GPPPAEEGIARVPIPGATGGPGMGRAAGRGVPSAGGLQGPVRGLGGPSSQMMQPQPGM-- RGPP-----FKLVLVGDGGVGKTTFVKRHLTGEFEKKYVATLGVEVHPLIFHTNRGPFRF NVWDTAGQEKFGGLRDGYYIQGQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCG NKVDIKDRKVKAKAIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLVGDPNLEFVEMPA LAPPEVHFDPQLAAKYEQELQEAQDVALPDEDEE-TEGIRQYYISKIEELQLVVTEKTQN LRRLEAQRNELNAKVRMLREELQLLQEQGSYVGEVVKPMDKKKVLVKVHPEGKFVVDLDK NIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEI KEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ KFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRLEGGSGGDSEVQRTMLELLNQLD GFEPKQNIKVIMATNRIDILDSALLRPGRIDRKIEFPAPNEEARLDILKIHSRKMNLTRG INLRKIAEMMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFELAVAKVMQKDSEKNMSI KKLWKLSFAENFALSGAAAIISKTAAAPIERVKLMVQNQDEMLKAGSLKEPYKGVVDCTV RTFKSEGVLPFWRGNLANCLRYFPTQALNFAFKDQIKKAFKSGAKDSYAIKFTKNVASGG AAGAMSLCFVYSLDYARTRLANDAKVSGKRQFNGLVDVYRKTLKSDGVVGLYRGFVISCV GIIVYRGCYFGFYDTLKPLLLGDDAGLFISFALGYVVTISAGLVSYPIDTIRRRMMMTSG QAVKYKGSFDCFVQIMKNEGPMSLMKGAGANILRGVAGAGVLAGFDKFKELYVAWRVMSD SSDLDRQIEQLRRCEIIKESEVKALCSKAREILVEESNVQRVDSPVTVCGDIHGQFYDLK ELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQV YGFYDECLRKYGSITVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSINTLDQIRAIDRK QEVPHDGPMCDLLWSDPEDTQGWGVSPRGAGFLFGSDVVAQFNAANDIDVICRAHQLVME GYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQRDFTIFEAAPQETRGKPQADYFL VRLPPEVNRILYVRNLPYKITAEEMYDIFGKYGAIRQIRMGSTPETKGTAFVVYEDIFDA KNACDHLSGFNVCNRYLVVLYYQSNKAFKKMDQEKKKEELDIMKAKYGLSTPEKKMSIGV PIKVLHEAEGHVVTCETNTGEVYRGKLVEAEDNMNCQMSNITVTYRDGRVAQLENVFIRG SKIRFLILPDMLKNAPMFKRVGAGRGKSAILRAAARGRGRS--------MQNEAGEFVDM YIPRKCSASNRIINAKDHASIQINFAEVDETTGRMTGSNKTYAICGAIRRMGESDDCILR LAKRDGVI---------------------------------------------------- ----------------------------------GFMDVVTIEKTSENFRLIYDVKGRFT VHRIQPEEAKYKLCKVKRVQTGPKGVPFLVTHDARTIRYPDPLIRVNDSVQVMGTKDDEY DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTA GQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADNNIVIMLVGNKSDL RHLRAVPTDEAKAFAEKNNLSFIETSALDSTNVETAFQNILTEIYKIVSQKQIRDSPDDN NVQTITVAPTDNSADRKKPCCTMSSRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVR GKDIVALGVEKKAVAKLQEDRTVRKIGLLDDHVAMAFAGLTADARILINRARVECQSHKL TVEDPVTLEYITRYIAQLKQKYTQSNGRRPFGLSTLIIGFDGTPHLYQTDPSGTYHEWKA NAIGRSAKTVREFLEKHFSDEIASEKEVIKLALKALLEVVQSGSKNMELAVMRRNQPLQM LESEEV---------------------------DKKDDKEKKRKYEPPVPTRVGKKKKKM KGPEAANKLPQVTPHTRCRLKLLKLERIKDYLLLEEEFIKNQERLKPQEEKQEEERSKVD DLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSIFSFVDKDQLEPGCSVLLNHKVHAVV GVLSDDTDPMVTVMKLEKAPQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIKPPK GVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPS IVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSRGDVKVVMATNRIETLDPA LIRPGRIDRKIEFPLPDEKTKRRIFNIHTARMTLADDVNIEDYVMAKDDLSGADIKAICT EAGLLALRERRMKVTNEDFRKAKENVLYRKNEGTPEGLYLKRKPYSPFQDSNYAEYALAR ADDLVNWARKSSLWPMTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQADCMIVAGTL TNKMAPALRKVYDQMPDPRWVISMGSCANGGGYYHYAYSVVRGCDRIVPVDIYVPGCPPS AEALLYGILQLQKKIKRMKRAQAWYRQTDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYA NNSNYKNDTMIRKEAYVHKSVMDELKRIIEDSEVMLEDDSLWPPPDRVGRQELEIVIGDE HISFTTSKIGSLVDVNQSKDPEGLRTFYYLVQDLKCLVFSLIGLHFKIKPI--------- -----------------YVLGYRQTLKTLRQGKAKLVIIANNTPPLRKSEIEYYAMLAKT GVHHYNGNNIELGTACGKYFRVTTLSITDPGDSDIIRSMPSGMTEYKLVVVGAGGVGKSA LTIQLIQNHFVEEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGF LCVFAINNTKSFEDINQYREQIKRVKDADEVPMVLVGNKVDLPTRTVETTQGKMLADTYG IPYVETSAKTRQGVDDAFYTLVREIRKYMGDRYNIHSQLEHLQSKYIGTGHADTNKWEWL TNQHRDSYSSYMGHFDMLNYFSLVENEAKARVRFNLMEKMLQPCGPPPERPEDMKIELCS FSGFKIYPGHGKKMVKTDGRVFQFINAKCEKSQLMKRNPRKINWTVLYRRKHKKGQTK-- --------------------------------------------------AKDASKPRVG GKR----------------EVDDEHKLRTFYEKRMAAEVTADHLGDEWKGYVVRISGGND KEGFPMKQGVLTTGRVRLLLAKGHSCYRPRRSGERKRKSVHGCIVDSNLSVLSLVIIKKG EKDIPGLTDTTVPRHLGPKRASKIRKLFNLSKEDDVRQYVVRRPLPPRTKAPKIQRLVTP LVLQRKRHRLALKRRRAAKKREDAAEYAKLLAQRMKEAKERKLERRRSASQSKKVKAKDL RGQKKEDLMKQLHELKTELASLRVSKVTGGAASKLSQIRTVRKSIARVLTVINQTQKENL RKFYKPKDLRXKKTRALRRALTKYELSLKT---------------------KGPKVTEKV FFDIAIGGEDVGRIVIGLFGKTVPKTVKNFRTLAEGTETYKGSKFHRVIKDFMIQGGDFT RGDGTGGRSIYFPDENFKLKHYGAGWLSMANAGKDTNGSQFFLTTKKTSWLDGRHVVFGK VLEGMKVVRKIENTKTGQDKPEKDVVIKDSGSLPVDTPFAVTKEDATEKKKKVVLKFTVD CTHPVEDGIMDSGNFEKFLHERIKVNGKTNNFKSKIVVTSXVPFSKRYLKYLTKKYLKKN NLRDWLRVVASTKDAYELRYFQINNEEEEEEEQL-------------------------- ----HEFIVKRDHALTSGTIKAMLSGPGQFAENETNEINFREIPSHVLQKVCMYFTYKVR YTNSSTEIPEFPIAPEIALELLMAANFLDC-KIITIEEMKQHKNSKSLWIAIHDSVYDVT KFLDEHPGGEEVLLEQGGGYATEAFEDVGHSTDARELMKDYLIGELAEADKSSWTSYLLP LGIAIAAALLYRFVMSYMLQHLKNGWQVDQAIMSEEDRVVVIRFGHDWDPTCMVMDETLY KCAEKMKNFAVCYLVDITAVPDFNKMYELYDPCTVMFFYRNKHIMIDLGTGNNNKINWSM EDSQEFIDIVETVYRGARKGRGLVVSPKDYSTKYRYKKLQRQLEFLEVQEEYIKDEQKNL KKEYLHAQEEVKRIQSVPLVIGQFLEAVDQNTGIVGSTTGSNYYVRILSTIDRELLKPSA SVALHKHSNALVDVLPPEADSSITMLQADEKPDVAYSDIGGMDIQKQEVREAVELPLTHF DLYKQIGIDPPRGVLMFGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVR DVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTVNVKVI MATNRADTLDPALLRPGRLDRKIEFPMPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPD KISGADINAICQEAGMQAVRENRYVVLAKDFEKGYKNNIKKDETEHEFYK-----TYDEI RDRVLNVCKEFDKVIAEKLTIDSHFMNDLGLDSLDQVEVIMAMEDEFGFEIPDADAEKLL RPADVVQYIADKQDV--------------------------------LREDLLRGVYAFG FEKPSAIQQRAIKPIVKGRDVIAQAQSGTGKTATFSISILQCLDTQIRETQALVLSPTRE LATQIQKVILALGDYMSVQCHACIGGTNVGEDIRKLDYGQHVVSGTPGRVFDMIRRRNLR TRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVLLISATLPHEILEMTSKFMTDPI RILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKM REANFTVSSMHGDMPQKERDAIMKEFRSGASRVLITTDVWARGIDVQQVSLVINYDLPNN RELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLIMALRRP FDPVAHELDPNFRLTKFSDLKGGCKVPQEVLLKLLEGL-QAQEAEQSHFQYVAAVPRIGI GMDSCVTPLRHGGLSLVQTTDFFYPLVDDPYMMGKIACSNVLSDLYAMGVTECDNMLMLM AVSNKMTEKERDVVVPLMIRGFKDLAEEAGTSVNGGQTVINPWMTIGGVATTVCQPNEFI MPDNAVVGDVLVLTKPLGTQVAVNAYQWLDQADRWNRIKLVVSEDDVRKAYQRAMFSMAR LNRTAARLMHKYNAHGATDVTGFGLLGHASNLARIQKNEVGFVIHNLPIIAKMAAVSKAC GNMFGLLQGHSAETSGGLLIALPREQAAAFCKDIEKQEGYQAWIIGIVEKGTRSARIIDK PRVIEVPAKEKEFIGTILGAVDCYFINIDAHAEECFFDKVTSGTKMSLMFEVAEGGFLDI DVKILGPDGKQIYSGDRESNGKYTFAAHMDGVYKYCFSNKMSTMTPKIIMFSMDIGEKPK AHHNKLEEMINELSTALTGVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMT LGQIYYLKRFFEVRRVVMAATLRPYLAAVRHTLTAAMCLENFNSQVVERHNKPEVEVRSS KELLLTPVVISRNEKEKVLIEGSVNSLRISIAVKQADEIEKILCHKFMRFMMMRAENFVV LRRKPVEGYDISFLITNFHTEQMYKHKLVDFIIHFMEEIDKEISEMKLAVNSRARISAEE FLKQFSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLV TMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTMPNTFKTLDSWRDEFLIQASPRDPEN FPFVVIGNKIDLENRAVSTKRAQGWCHSKGDIPYFETSAKEAINVEQAFQTVAKNALAQE TEVELYNEFPDQIKIT----------TAVFDARFPNQNQTRNCWQNYVDYHRCHKIDDYE PCEYFKRVYRSLCPNSWTAQWDEQLEAGSFAGKIMPDHLGADQRKVHDEDEEEKPIQALD EGDIALLKSYGAGMYSGSIKKIEEDTQNILKRVNELTGIKESDTGLAPPALWDLAADKQT LQSEQPLQVARCTKIINADSDEPKYIINVKQFAKFVVDLSEQVAPTDIEEGMRVGVDRNK YQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIDKLREVVETPLLHPERFVNLGI DPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMART KKACIIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDT LDPALTRPGRLDRKVEFGLPDLEGRSHIFKIHARSMSVEKDIRYELLARLCPNCTGAEIR SVCTEAGMFAIRARRKMATEKDFLEAVNKVIKAYAKFSATPRYMTYN------------- ------------------------------------------------------------ ----------KYYITIIDAPGHRDFIKNMITGTSQADCAVLVVAAGIGEFEAGISKTGQT REHALLAFTLGVKQLIVAINKMDLSQPSYSEERYNEIKKEVSTFIKKVGYNPAAVAFVPC SGWNGDNMINMSWFDGWKIASGYTLLDALDSILAPKRPTDKPLRLPLQDVYKISGIGTVP VGRVETGTMKPGNIVTFAPALLTTEVKSIEMHHTTLAEAFPGDNVGFNVKNVSVKDVKRG NVCGDSSNDPPKEAVTFNAQVIILNHPGEIHAGYAPVVDCHTAHIACKFTELMEKNDRRS GKKLEDAPKFVKSGDAAMVLMTPSKPICVEAFSDYPPLGRFAVRDMKQTVAVGVIKSVEK SSGEKGKVTKAAQKAELEQLRQEAEQLKNQIREARKAAADTTLVQATSVVEAVGRIQMRT RRTLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAP SGSYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIVTSSGDMTCA LWDIETGQQTTSFTGHTGDVMSLSLSPDMRTFVSGACDASAKLWDIRDGMCKQTFSGHES DINAITYFPNGYAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLG -----------------------------------------------------MSYAYLF KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES FRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARR DVKKEEGEAFAREHGLVFMETSAKTAANVEEAFINTAKEIYQKIQDGVFDINNEANGIKI GPQHSPTNPSGGGGANQGGG---------------------------------------- --------AYFNDIVVGAVCCREDKTDNQRRLYIMTLGCLAPYRRLGIGTVMLQHVLRIC EEDANFDNVFLHVQVNNEGAIKFYEKFGFEIVEQKQNYYKRIEPADAFVLQKTFRKMPKQ IMEIKDFLLTARRKDAKSVKIKKNVKFKVRCSQ--------------------------- ------------------------------------------------------------ ---------------------------------NKKLVKKLAKKYDAFLASDSLIKQIPR ILGPGLNKAGKFPTPLTHNEHMTGKIDEVKATIKFQMKKVLCLAVAVGHVNMTSDSLIKQ I----------------------------------MAEADKLNIDSIIARLLEVRGSRPG KNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLNAGRPVTPPRGSAKSK GKMMFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEVSGTNVSTT YITCPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPF ICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDEL PAEFKLYLPVQQK-----IENLKDPFCEADVIHIRIQQRNGRKTLTTVQGISDEYDKKKI AKCCKKEFACNGTVVTHPEYGQVIQFQGDQRDKVAEFLVKLGFKDQIKVHGFSAIFNFQS LLTVVLLLICTCAYIRSIAPRMLDKNKEGLLGIFWKCARIGERKSPYVAICCIAMAVSIL FFS--------------------------------------------------------- ----SIGDGIARVYGLKNIQAEEMVEFSSGLKGMALNLEPDNVGIVVFGNDKLIKEGDIV KRTGAIVDVPVGLEILGRVVDALGNPIDGKGPLNASARQRVGIKAPGIIPRISVKEPMQT GIKAVDSLVPIGRGQRELIIGDRQTGKTAVAIDTIINQKRFNDGQNEKEKLYCIYVAIGQ KRSTVAQIVKRLTAADAMKYTIIVSATASDAAPLQYLAPYAGCAMGEYFRDNGKHAVIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSDNFGGGSLTALPVIE TQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTKAMKQVAG SMKLELAQYREVAAFAQFGSDLDASTQALLNRGVRLTELLKQGQYVPMAIEEQVAVIYAG VKGHLDKLDPSRITQFETEYLQHVKTQHQDLLNTIREDGKITDATDAKLKKVVVDFIAGF ------------------------------------------------------------ --------------------------------------------DQTNKPMMPKLNRILL LSVGFVCILVSFFMCRVFMRMKLP--KMKRSKKPPPDGWELIEPTLDELDQKMREAETEP HEGKRKVESLWPIFRIHHQKSRYIYDLFYRRKAISRELYEYCLKEAIADKNLIAKWKKQG YENLCCLRCIQTRDTNFGANCICRVPKSKLEEGKIVECVHCGCRGCSGEYAQVIKMLGNG RLEAMCFDGNKRLCHIRGKLRKKVWINTSDIILVGLRDYQDVKADVILKYTPDEARNLKA YGELPENTKIDANEEDNIAFDEIDDILVRFLMKLSHETVTIELKNGTQVHGTITGVDVSM NTHLKTVKMTVKNKDPVQLESISIRGNNIRYFILPDSLPLDTLLIDDAPKAKARK----- -----------QREQEEFNTGPLSVLTQSVKNNTQVLISCRNNKKLLGRVKAFDRHCNIV LENVKEMWTEVPKTGKGKKKSKPVNKDRYISKMFLRGDSVILVLRNPL------------ ----------------------------HFYRNKLKYLDFLRKRCNTKPSRGPYHFRAPS KIFWRTVRGMLPHKLKRGKEALDRMKVF-------------------------------- -----------------------------------------------------------A GDPVKGKKLFVQRCAQCHVVEKGKGHKTGPNLNGLFGRKTGQAPGFSYTDANKNKGIVWG KDTLWVYLENPKKYIPGTKMIFAGLKKTKERADL---------IFVERTLAIIKPDALSE EIEDIILRSGFSILQKRRVHLTPEQASDFYAEHYGKLFFPSLVSYMSYGPVLALVISRDK AISYWRELIGPTNTMKAKQTHPDCLRAIYGTDDQRNGLHGSDSYSSAAREIRFFFPDSVV EPIPVGQAAKDYLARAVNPTLLKGLTELCKQKPRDPVVWLADWLLDNNPNKPKVKMFEAR LVQGALLKKVIEAIKDLLTEATWDCNGTGIGLQAMDSSHVSLVSLNLRSDGFDTYRCDRN LSMGINLGSMSKILKCAGNDDAITVKADDNADTVTFVFESTNGEKVSDYEMKLMDRDVEH LGIPETDYNCVIKMPSAEFQRICRDLSQIGESVVICCTKEGVKFSASGDLGTGNIKLAQS ANVDKEEEAVIIEMNEGVVLTFALRYLNYFTKATPLSPQVTLSMSPDVPLVVEYKIADMG HVRFYLAPKIEDEEGA-------------------------------------------- --------------ENTVRTIAMDGTEGLVRGQVCVDVGTPIRIPVGRETLGRIINVIGE PIDERGPVNAKMQAPIHAEAPEFVEMSTEQEILETGIKVVDLLAPYCKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVINLTDDTSKVSLVYG QMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTKSGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIA ELGIYPAVDPLDSTSRILDPNIVGTLHYQVARGVQKILQDYKSLQDIIAILGMDELSEED KLTVARARKIQKFLSQPFQVAEVFTGSEGKLVPLKDTIKGFKQILDGELDHLPEVAFYMV GPIEEVISKAERLAEEH----------IYECLFKEGVLVAKKDFHAPKHPEXEVPNLHVI KAMQSLKSRGLVKEQFAWRHFYWYLTNEGI------------------------------ -----------------MGKQNSKLKPEVLEDLRQNTEFTDEEIQEWYKGFLKDCPSGHL SVDEFKKIYGNFFPYGDASKFAEHVFRTFDTNGDGTIDFREFICALSVTSRGKLEQKLKW AFSMYDLDGNGYISRQEMLEIVTAIYKMVGTVMKMPEDESTPEKRTDKIFRQMDKNLDGK LSLEEFIEGAKSDPSIVRLLQCDPMSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNL TGLNEQVPHYRQALDMILDLEPDDELEDNPNQSDLIEQAAEMLYGLIHARYIMTNRGIAQ MIEKWQQGDFGYCPRVYCENQPMLPIGLSDVPGEAMVKLYCPKCQDVYTPKSSRHHHTDG AYFGTGFPHMLYMVHPEYRPKRPANQFVPRLYGFKIHPMAYQMQWQAAS----------- ---------------------KGVIPLGTYMKVYKRGDIVDIKGNGAVQKGMPHKSYHGR TGRIYNVTPHAVGVIVNKRVKGRILAKRINVRIEHVKHSNCRLDFINRVHENEKKKRAAK ARVECKRQPLQPRAGHFVSTKYNKPEYL-------------------------------- -----------------------KEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAICPAQAITIEAEPRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEY STETHEELLYNKEKLLENGDKWEAEIAANLQADYLYR------------------DAETQ KALEEIDACQNDIDALNEKASEEILKVEQKYNKLRKPHFEKRNDLIKKIPNFWVTAFVNH PQISAILDEEEEECLHYLNKVEVEEFEDIKSGYRIKLHFSENPFFENDVLCKEFHLAASQ SMPMKWKEGMDLTKRARKRKLGPTRTFFQWYLDNTDPSADDIAEVIKDDMWPNPLQYFLA PDIEVEENDDDDLDESVKKLTKEEELLLQDFSRNVTTKSSALFYGNAFIVSAIPMWLFWR IHQMEPYVLFGIMTIVSTYLVAMAYRNVKFLLKHKIAQRREEAVSREVMKKVADDKKMSK KEKDERILWKKNEVADYEATTFSIFYNNALYLVLIIIASFYLLKSFSPTVNYVLSV---- -----------ATQGKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQT VCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVKELQRQ ASPNIVIALAGNKADLRMVEYDEAQAYAEENSLLFMETSAKTAMNVNDIFLAIAKKLPKN EQAIDISQDN-------------------------------------------------- ------------------------FFEEIFIELEDKYGEIEEMNVCDNLGDHLVGNVYVK FRYEEDAEKAVADLNNRWFNGRPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHQKP ISRELRRKLYGRNRRSRSRSPPTRR--------------------MFLTRSEYDRGVNTF SPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVVLAVEKRVTSPLIEPSSIEKIMEVDSHIG CAMSGLIADSRTMIDRARVEAQNHWFTYNEKMSVESVTQAVSNLALAFGDDDADPGAMSR PFGVALLFAGIDAKGPQLFHMDPSGTFIQYDAKAIGSGSEGAQQALQEIYHKSMTLKEAC KHALTILKQVMEEKLNATNVEMGTVTPQNQFKMFTKEKLEDVI----------------- ----------KKQQQDILTAKPWDKDPHYFKYIKISALALLKMVMHARSGGNLEVMGLML GKVDGNTMMVMDSFALPVEGTETRVNAQAQAYEYMAAYTESAKQVGRLENAIGWYHSHPG YGCWLSGIDVSTQMLNQQFQEPFVAIVVDPVRTISAGKVNLGAFRTYPKGYKPPDEGPSE YQSIPLNKIEDFGVHCKQYYALDVSYFKSSMDRKLLESLWNKYWVNTLSSSSLLTNADYT TGQIFDLADKLEQSEAQLGRGGFMEKKSEDKLSKATKDGCKNTIEAIHGLMSQVIKDRLF NQV--LPKRIIKESMRLKSEPVPGISAEPCENNARYFTVVIAGPEESPYSGGIFKLELFL PEEYPMAAPKVRFLTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPD DPLANDVAEQWKSDESAAIEQAREWTKKYA---EELLDYEE-DEHEAKDVKGTYVSIHSS GFRDFLLKPELLRSIVDCGFEHPSEVQHECIPQGILAMDVLCQAKSGMGKTAVFVLATLQ QLEPVDGQVSVLVLCHTRELAFQISKEYERFSKYMNNVKIAVFFGGMAIKKDEEVLKKNC PHIVVGTPGRVLALGKSLNLKHVKHFILDECDKMLEQLDMRRDVQDIFRMTPHEKQVMMF SATLSKDIRPVCKKFMQDPMEVYVDDDSKLTLHG------------KNRKLFELLDVLEF NQVIIFVKSVQRCMALAQLLVEQNFPAIAIHRAMTQEERFSRYKEFKDFQKRILVTTKPF GRGMDRKQVNMVFNYDMPE---------------------------------PPSYGDLG KAARDLFNKGFNYGFYKLECKTKANNGIQFTVNGNSNHDTNKTTGNLETKYKWNDYGLTF LEKWNTDNTLGTEITIEDQLAKGLKLSFDTEFAPQTGKKSGKIKTAYKQDYININADVDF DFAGPTIHGAAVLGYNGWLAGYQMSFDKSKLARSNFAVGYTTDDFTLHTNVNDGAEFGGS IYQRVNDELETGVQLSWTAGSNATRFGLCAKYTPDKDSSIRAKVNNSSQIGLSYQQKIKD GVNITLSSLIEGKNFNQGGHKVGFGLEFEANSTREKALTDYRKKLLEHKELEARLKEMRE QLKELTKQYDKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQIDKAK LRAGTRVALDMTTLTIMRHLPREVDPLVYNMSMEDPGDIGYSQIGGLGEQIRELREVIEL PLMNPELFQRVGITPPKGCLLYGPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIGES ARLIREMFGYARDHQPCIIFMDEIDAIRRFSEGTSADREIQRTLMELLNQMDGFDALGQV KIIMATNRPDTLDPALLRPGRLDRKIEIPLPNEQARMDILKIHASPIAKHGEIDWEAVVK LSDDFNGADLRNVCTEAGMFAIRAERDYVIEEDFMKAVRKVADNKKLESKLDYKPLMPDT LGSVIHRFYDEYMSSTPKKLKIIDSYLLYIMLTGIVQFGYCALVGTFPFNSFLSGFISCV GSFVLAVCLRMQVNPQNKTDFTGISPERAFADFIFAHVILHLVVINFIGTLASPSQLLPL ELVDKCIGSRIHIIMKNDKEIVGTLLGFDDYVNMVLEDVTEFESTPEGRRVTKLDHILLN GNNITMLVPGGEGPEVIDHYENPRNVGSLDKEDSNVGTGLVGAPACGDVMKLQIKVDDDG RIVDAKFKTFGCGSAIASSSLATEWIKGRTLTEASEIKNSHIAKELCLPPVKLHCSMLAE DAIKAALSDYKVKKQMLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKES FDYLKTLASDVHIVRGDFDENLHYPEQKVVTVGQFRIGLCHGHQVVPWGDTESLAMIQRQ LDVDILITGHTHKFEAFEHENKFYINPGSATGAYNPLDSSIVPSFVLLDIQQSTVVAYVY QLVVDDVKVERIEYKKMGKFMKGGKVVLVLSGRFAGRKAVIVKNYDDGTQDKPYGHALVA GIDRYPRKVTKRMGKKKIKQRSKVKAFVRVLNYNHMMPTRYSVVNLDKTLVNKDAFRDPA LRRKARREAKARSQRLHKRPRRR--------ERTFIMVKPDAVQRGLVGEIIRRFERRGF KLVAMKFMLASQDLLAQHYAEHKGKPFYAKLLDYIGSGPVVPMVWEGNAVKVGRDMLGAT DPAKSAMGTIRGDFCLEMGRNACHGSDSVPTAQREISLWFDDKELIDWNPVQHDWVFE-- -PKPVKSGGKGKDKALKAKKAVLRGVHDRRNRKKRTIVQFKRPRTLRLPRDPKYPRKSTP RRNRLDQFKIVRFPLTTESAMKKIEDNNTLVFIVDKRSNKPQIKAAVKQLYDIDVSKVNT LIRPDGEKKAYVRLA----------------------RIQNEKHSKNVINRGNVPKTLKA AEDKLPVGPWLLGLFVFVVCGSAIFQIIQSIRMXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---FI LIQNRAGKTRLAKWYMHFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIVYRRYAGL YFCICVDVSDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYSVVDEMFLAGEIRE TSQTKVLKQLLMLSSLE------KIIDRSIPADIIYEDSLSLAFNDVNPMAPVHFLVIPK KPIPGISEDEQLMGHLMLVARKVAKQDNGYRIVINNGPDGAQSVYHLHIHVMGGRQMSWP PMGGFFSLFSGLFGARERRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVTYKN LKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSMDRDRIGISKQELVSMLEEDELKKAI LVVFANKQDIEGAMTVTEVANALGLSALKNRKYQIFKTSAIKGEGLDEAMEWLANSIQNT K-------------------------GNYKVQMFDPNINDYLPTTPGLGMHVEVKDPETK VVLGRTYAAEGRFTFTSHTAGEHIICLHSNSTAWFGGGQLRIHLDIQVGEHANDYQQIAA KDKLTELQLRVRQLLDQVEQITKEQNYQRYREERFRQTSESTNQRVLWWSIAQTVILLIT GFWQMRHLKGFFEAKKLV--------------------NLLNTVKQKLFTEVEGTCTGKY GFVIAVTTIDNIGAGYIQPSRGFVVYPVKYKAIVFRPFKGEVLDAVVTQVNKVGLFTEIG PLSCFISRHSIPADMEFDPNSNPPCYKTKDEDMVIQQDDEIRIKIVGTRVDATDIFAIGS LMDDYLGLVSRLYSKAIFSGFKRGLRNQHENTALLKIEGVHTKQETDFYLGKRCAYVYKA RNKTACPGHDKASRIRVIWGKITRPHGNSG------------------------MAKKTY DLLFKLLLIGDSGVGKTCLLFRFSDDAFNTTFISTIGIDFKIKTVELGGKKIKLQIWDTA GQERFHTITTSYYRGAMGIMLVYDITNAKTFDNISKWLRNIDEHANEDVEKMILGNKCDM EDKRQVSKERGDSIAREHCIPFLETSAKSNINVEKAFMDLAQAILNK------------- ------------------------------------------------------------ ----------------------QTRAKVLSNMIKQKRKEKAGKWEVPLPKVKGVSEAEVF KVVKTGKSRRKAWKRMVTKVTYVGEGFTRKPPKYERFIRPMGLRFKKAHVTHPELKATFC LPIIGVKKNPTSPLYTSLGVITKGTIIEVNISELGLVTQGGKVVWGKYAQVTNNPENDGC INAVLLV----------------------------------------------------- ------------------------------------------------------------ ----------------------------------EVPLVISDKVEEYKKTKEAVGLLRRL KAWPDIEKVYSSKRFRAGKGKMRNRRRIQRRGPLIIYNQDNGISRAFRNIPGITLINVSR LNLLKIAPGGHVGRFCIWTESAFKKLDAIYGTWRKQSKEKNNYNLPMPKMTNSDLSRLLK S----------------------------------------------------------- -----------------GSGEQELATRTLQIQSKRFYLDVKQNRRGRFIKVAEVGAGGKK SRLLLAMSTAAEFRDHLTEFSEHYASLGPPNPENLPEDGKLKSEVMVKDNRRYYLDLKEN ARGRFLRVSPRSSQRSQIAIPAQGMIEFRDALTDLLDEFGTDDHEGPGELPEPRSMRVEN KMFYFDVGQNRRGVYMRISETNFRTAVTIPERSWARFRDIISDFVDKQERKIRDAQMRAT INQKLVETGERERLKELLRTRLIECGWRDQLKAYCKDVVRQKGLEHITVDDLVAEITPKG RALVPDQVKKELLQRIRSFLAQQSN----------------------------------- ------------EKGKIVGYVLAKMEEDPEDSVPHGHITSLAVKRSHRRLGLAQKLMDQA SRAMVECFNAKYVSLHVRKSNRAALHLYTNTLKFAISEIEPKYYADGEDAYAMRRDLSEF LDK-MSHTILLVQPGRKPEGRTYSDYESVNECLEGICKIYEEYLKRNNPNSPSITYDISQ LFDFIDTLADLSCLVFNKSTGMYIPHNKDWIKEKIYILLRKQAGKMAEEGGEKKAEETKR IIHTYPLIRHSDMNEEMRTETMELCVTACEKFSNNNETAAKMIKETMDKKFGASWHAVVG EGFGFELTHEVKNLLYLFFGGNMAIIVWKCS----KFSAPRHGSLGFLPKKRSRRHRGKV KAFPKDDPSKPPHLTAFISYKAGMTHIVREVDRPGSKVNKKEIVECVTILETPPMVMVGV VGYIETPKGLRTFKTVFAEHLSDECKRRFYKNWYRSKKK--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------KEGKVVKNNASTEYDLTEKTITPMGGFPHYGEVNND FVMIKGCCMGPKKRVITLRKSLLVHTKRKATEKITLKFIDTSSK---------------- ------MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLG LWDTAGQEDYDRLRPLSYPQTDVFLICFSLISPASFENVRAKWFPEVSHHCPNTPIILVG TKLDLREDKETVEKLKEKKLSPITYPQGLAMAKEIGAVKYLECSALTQKGLKTVFDEAIR AVLCPKPKPKKNRGCRILIFDPTMKRKKKKKTPFDLDAALDELLLDDGLAKKKKKKKKPF DFSEIDDALPKEETSLPMKKKKVDSDRDYTYDELLKRVFEIMREKNPDMVAGEKKRFVMK PPQVMRVGTKKSSFSNFAEICKMLHRQPKHLLAFLLAELGTSGSVDGNNQLIIKGRFQQK QIENVLRRYIKEYVTCHTCRSPDTILQKDTRLFFLQCETCGSRCSVASIKSGFQAVTGKR AAIRAKTSFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGK DYSLHRLILGTHTSDEQNHLLIASVQLPNDNAQFDASHYDSEKGEFGGFGSVSGKIEIEI KINHEGEVNRARYMPQNPCVIATKTPSSDVLVFDYTKHPSKPDPSGECSPELRLKGHQKE GYGLSWNPNLNGHLLSASDDHTICLWDINTTPKEGRVIDAMTIFTGHTSVVEDVSWHLLH ESLFGSVADDQKLMIWDTRSNNTSKPSHTVDAHTAEVNCLSFNPYSEFILATGSADKSVA LWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQSAEDA EDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEEPDTPAS ELEMPAPSRARVYADVNTHRPREYWDYESHVVEWGQQDDYQIVRKLGRGKYSEVFEAINI TNNEKCVIKILKPVKKKKIKREIKILENLRTGTNIITLLAIVKDPVSRTPALIFEHVNNT DFKQLYQTLTDYDIRYYVFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLA EFYHPNQEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPFFHGHDNY DQLVRIAKVLGTEELYEYIDKYQIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALD FLDKLLRYDHAERLTAREAMEHPYF----------------------------------- ------------------------------------------------------------ --------------------------------------VYKRGYAKVDHKRVPLTNNDII EESLGKYGIICMEDLIHEIFTVGPNFRHANNFLWPFKLNTPTGGWRKKNNHFVEGGDFGN RDDKINNLLKKMMQFMLLFSRQGKLRLQKWYVAHPDKLKKKITRELITTILARKPKMCSF LEWKDLKIVYKRYASLYFCCAIENEDNELLTLEIIHRYVELLDKYFGSVCELDIIFNFEK AYFMLDELLLGGEVQETSKKNVLKAIAAQDLLQEETPQGFFEDHGLGMSKAHPPELKKYM DKKLALKLNGGRTVSGILRGFDPFMNLVVDEAMEETKSGEKHSIGMVVIRGNSIVLLESL ERIEFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTI RLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFQQTSKWIDDVRTERGSDVIIM LVGNKTDLSDKRQVSTEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMEQTEQ KKMIEVKLKDTPAEPQK----------LNKGHKVTIRKPRPSRRKGKLNKHVKFIRDIVR EVCGMAPYERRCVELLRISKDKRALKFCKKRLGTHIRGKRK--------------XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----FDFLDDVRRMNARQLYYQ VLNFAMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNYREEPIRVGE IVVFKVEGREIPIVHRVLKVHERENGTVKFLTKGDNNSVDDRGLYAPGQLWLEKKDVVGR ARGFVPYVGIVTILMNDYPKFKYAILALLGLFVLIHREMSTMNPEYDYLFKLLLIGDSGV GKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYR GAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEY ADQLGIPFLETSAKNATNVEQAFMTMAAEIKNRMGPVSAAPNVKINPSTPVKQGGGSCC- ----EEVLRMSNEEVVSRTRLLDNEIKIMKSEVMRISHELQAQKEKIKENTEKIKVNKTL PYLVSNVIELLDVDPQDQGEEDGANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDPENL KPGDLVGVNKDSYLILETLPQEYDSRVKAMEVDERPTEQYGDIGGLDKQIQELIEAVVLP MTHKERFETIGIEPPKGVLLYGPPGTGKTLMARACAAQTKSTFLKLAGPQLVQMFIGDGA KLVRDAFALAKEKAPAIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPSND IKVIAATNRVDILDPALLRSGRLDRKIEFPCPNEEARARILQIHSRKMNVRSDVNYEELA RCTDDFNGAQCKAVCVEAGMIALRREATELTHEDYMDAILEVQAKKKANLQYYAKDAADQ NFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRQDKRVKLQIWD TAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDNAQVVLVGNKC DLEDERVVSTERGKQLADQLGLEFFETSAKENINVKAVFERLVDIICDKMSESLDSDPTQ TKRLTENPNPQNGGCQC--THKLAVTRNYISQPRITYKTVSGVNGPLVILDDVKFPKFAE IVQLTLNDGSQRTGQVLEVSGSKAVVQVFEGTSGIDAKHTTCEFTGDILRIPVSEDMLGR IFNGSGKPVDKGPPVLAEDFLDIQGQPINPWSRIYPEEMIQTGISAIDGMNSIARGQKIP IFSANGLPHNEIAAQICRQAGLVKLPEKSVMDDHEENFCIIFAAMGVNMETARFFKQDFE ENGSMENVCLFLNLANDPTIERIITPRIALTTAEFFAYQCEKHVLVILTDMSSYAEALRE VSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLT GYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTREDHADVSNQLYACYAIG KDVQAMKAVVGEEALTPEDLLYLEFLQKFEKNFIAQDNYENRSIYETLDVGWQLLRIFPK ELLKRIPQQKLAKYYPRDS----------------------------------------- --------NKITHEVDELTQIIADVIADPTLPRTEDHPCPRCGHKEAVFFQSQTTRSEEG MRLYYVCTLQSCAHRWTE--------------GQRALEVAENEMPGLMSMRKLYGASKPL KGARIAGCLHMTVQTAVLIDTLRELGAEVQWSSCNIFSTQDHAAAYIAKSGVPVYAWKGE TDEEYIWCIEQTIMFGD-KPLNMILDDGGDLTNLVHEKYPNLLEGIKGLSEETTTGVHNL YKMLADGKLKCPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGKVAVVGGYGDV GKGCAAALRAFGARVIVTEIDPINALQAAMEGYEVSTIEETLKEARIYVTATGCHGILKG EHFEQMLEDTIVCNIGHFDCEIDVKWLQDNCKEKNTIKPQVDRYTLKNGRHIILLAEGRL VNLGCAMGHPSFVMSNSFTNQVLAQIELWTKADQYKIGVHFLPKKLDEEVAAAHLDHLGV KLTQLTEAQSKYLGIPQKGPFKPEHYRY--------ANTVEEPLDLIRLSLDERIYVKMR NDRELRGRLHAYDQHLNMILGDVEETVTTMEIDEETYEEIYKSTKRNIPMLFVRGDGVIL VSPPMRTMSTSNVENLSPQIIRQVAKEISTLTSDPPEGIKVFPNEEDITDIQATIEGPAG TPYAGGVFKMKLVLGKNFPNEPPKGFFLTKIFHPNVASNGEICVNVLKKDWKAELGIKHV LLTIKCLLIVPNPESALNEEAGKLLLEQYDDYSMRAKMYTEIHAKP-------------- ----GLKVNETRTIAAP-EETSCEFGSSKYYALCGFGGILSCGITHTAVVPLDLVKCRIQ VDPSKYKNIINGFKVTLREGGPRELGRGWAPTFIGYSMQGLCKFGFYEVFKIFYGNLLGE EKTYLYRTSLYLAASASAEFFADIALCPMEAVKVRIQTQPGWARTLREGVPKLMKEEGAW GFYKGIVPLWGRQIPYTMMKFACFERTVEALYKYVVPKPRSQCSKPEQLVVTFVAGYIAG VFCAIVSHPADTIVSKLNQDKGSSFVEVGKKLGLMGMWKGLFPRIIMIGTLTALQWFIYD SVKVYFRLPRPPPPEMPESLKRKL-HWKQERAVIFALMASVPAGLIYPLDYTIASLVMHT YWGLGAIFTDYVHLSIGTFAGLCLLTYNDIGVARTIR------XXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNLQPHLAKQ ELDKLEVSKLTPLTPEVISRQATINIGTIGHVAHGKSTVVKAISGVQTVRFKNELERNIT IKLGYANAKVYKCDDEAVPRPQCYTSRGSAHPDSFPCDYRNSGKYQLVRHVSFVDCPGHD ILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQ AREQYEQILRFVQGTIAEGAPVIPISAQLKYNIDAVCEYVVKTIPVPVRDFTSQPRLIVI RSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKDQEGKLTCKPIFSRIV SLFAEQNDLQFAVPGGLIGVGTKIDPTLCRADRLVGHVLGAVGALPDIYIELEISYFLLR RLLGVRTEGDKKGAKVQKLSKNEILMVNIGSLSSGGRVLAVKADLAKIGLTSPVCTEIGE KIALSRRVEKHWRLIGWGQIRRGVTVKP--ELLLDSDIRLWVFLPIVLITFLVGIIRHYV TILLSSEKKVELQQIADSQALIRSRMLRENGRFVPKQSFLMRKEYFNNEDSGYLMKNPMT DPTMMSDMLKGNITNVLPMIVIGGWINWAFSGFLTTKVPFPLTLRFKPMLQRGVELASLD ASWVSSASWYFLNVFGLRSMYNLILGQDNAADQTKVMQDQMSGAAMAMPPDPSKAFKAEW EALEICDHQWALEGVEDEI-MFLWDWFTNMLNFLGLYKKSGKLVFLGLDNAGKTTLLHML KDDRMAQHVPTLHPTSEELSMGGMKFTTFDLGGHQQARRVWKDYFPAVDGIVFLIDALDR ERYVEAKAELDSLLTDEQVASAPVLILGNKIDVAGAASEDEIRHIFGLHGQTTGKGVVAR SELRPMELFMCSVLKRQGYGEGFRWLAQYIN----------------------------- AVQQFIQQAIKRDFNNIDEILNPPEGQDEGVWKYEHLRQFCMELNGLAVKLQAECNPETC TQMTATEQWIFLCAAHKTPKECPAIDYTRHTLDGAACLLNSNKYFPSRVSIKDSSVAKLG SVCRRVYRIFSHAYFHHRSLFDEYENETGLCKRFTTFVTKYQLMSKDNLIVPILEDQ--- -----------------------IKTMLEDDEDEDDVVPLPNVNAAILKKVIQWCTYHKD DPPPPEDDENKEKRTDDISSWDAEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMI KGKTPEEIRKTFNIKNDFTPAEEEQVRKENEWCEEK------------------------ ------------------LVTRTQGTKIASEGLKGRXFEVSLADLQNDEVAFRKFKLVAE EVQGRNVLTNFHGMNLTTDKLRSMVKKWQTLIEANVDVRTTDAFLLRLFCIGFTKKRQNQ IKKTCYAQHTQVRAIRKKMVEIMSREVSSNDLKEVVNKLIPDSIGKDIEKACQGIYPLHD VYIRKVKILKKPKFDLGKLMELHGEGGTTVTTEGGEKVDRPEGYEPP-----MSASAVYI LDIKGKVLICRNYRGDIDMSVIDKFMPLLMDREEDGNVAPIIQHGPTAFVYIKYNNLFLV ATSKKNSNVAMVFTFLHKIVQVFIEYFKELEEESIRDNFVMIYELLDELMDFGYPQTTDS KILQEFITQEGHKLEVAPRPPPAVTNAVSWRSEGIKYRKNEVFLDVIESVNLLVSANGNV LRSEIVGAIKMRVYLSGMPELRLGLNDKVLFESTGRGKSKSVELEDVKFHQCVRLSRFEN DRTISFVPPDGEFELMSYRLNTHVKPLIWVESVIERHVHSRVEYMIKAKSQFKRRSTANN VEIVIPVPADADSPKFKTTTGSCKYAPDQNAVVWTIKSFPGGKEYLMRAHFGLPSVEAED NEGRPPIHVRFEIPYFTVSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRTQMGILDK IAEIEAEMARTQRNKATMGHLGLLKARLAKLRRELIEPKGGGGGAGEGFDVAKTGDARIG FIGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDG KGRGKQVIAVARTASLILIVLDVLKPLQHKKLIEHELEGFGIRLNKTPPNISFRRKDKGG INLTATVSQSELDLDTVKAILGEYRIHNADITLRIDATAEDLIDVVEGNRVYIPCIYVLN KIDQISIEELDIIYKIPHCVPISAHNKWNFDDLLEKIWDYLRLVRIYTKPKGQLPDYESP VVLKRDQQIIEDFCNKLHRTIIKEFKHALVWGSSVKHQPQKVGKDHFLQDEDVVQIVKKM AKHHPDLIFCRKQPGVAIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGSYQGRCVIC GGPGVSDAYYCKECTIMEKDRDGCPKIVNLGSAKTDLFYERKKYGFKKRPNLPPISGEKL MGKTELRKIPVPANRYTPLKENWMKIFTPIVEHLHLQIRFNLKTRNVEIKTCKETRDVGA LQKAADFVKAFTLGFEVEDALALMRLDDLYLESFQITDVKPLKGDHLARAIGRIAGKGGK TKFTIENVTKCRIVLADTKIHILGSFQNIKIARTAICNLILGSPPSKVYGNMRA------ --RIKVAKPVVELDGDEMTRIIWEKIKEKLVFPYVDVECLYYDLGLPYRDQTNDQVTIDS ALAIQKHNVGIKCATITPDEERVEEFKLKKMWLSPNGTIRNILGGTVFREPIICKSIPRL VPGWSQAITIGRHAHGDQYRATDFVATKPGKLELVFTPHDGSDNRMEVYDFKDRGGVGLS MYNTDESIEGFAHACFQYALKKKWPLYMSTKNTILKRYDGRFKDIFQEIFEAQYEKDFEA AGIWYEHRLIDDMVAQALKSSGGFVWGCKNYDGDVQSDVVAQGYGSLGLMTSVLMCPDGK TVEAEAAHGTVTRHYREHQKGNPTSTNPVASIFAWTRGLDHRATLDGNPDLSRYCNLLEK ACVDTIDSGKMTKDLAGCIYGLKNVKPEQYLYTMDFLEAIAEQFEMGKLLSKIFGNKEMR ILMLGLDAAGKTTVLYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWR HYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMKPHEI QEKLGLTRIRDRNWYVQPSCATTGDGLYEGLTWLTSNAKS---LSSNTGLQALNDFLCDK SYIEGYGPSQADVAVFEAVKSPGSSFAHALRWYNHIKSYGNDRKTFPGKKQNAEFYIFGT TDKDEDDDDLDLFGSELERIKQERVKAYEAKKSPALVAKSNIILDVKPWDDETDMKEVEK VVRSIATDGLRWGASKLVDLAYGVKKLQISCVVEDDKVGTDFLEESITAYEALVQSVDVA AFNKV---EIREVTRIERIGAHSHIRGLGLDDSLEARQVSQGMVGQTTARRAAGVILEMI KDGKIAGRAVLIAGHPGTGKTAIAMGMAQALGTDTPFTSIAGSEIFSLEMSKTEALTQAF RRSIGVRIKEETEIIEGEVVEIQIDRPATGTGAKVGKLTLKTTEMETIYDLGQKMIESLT KEKVQAGDIITIDKATGKITKLGRSFTRARDYDAMGPQTKFVQCPEGELQKRKEVVHTVS LHEIDVINSRTQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIVPGVLFIDEVHM LDIECFSFLNRALESDMAPILIMATNRGITRIRGTQYQSPHGIPIDLLDRLLIISTSPYE EKEIKQILKIRCEEEDVEMSDEALTVLTRIGIETSLRYAIQLITAANLVCRKRKGAEVSM DDIKRVYSLFLDESRSTQFLKEYQQEFMFNEMAEFDLTTRMGQYLDRHLVFPLLEFLSVK EIYDEKEMLKGKLDLLSNTNMVDFAMDVYKSLYPDQDVPSTLKEKRTEVVAELKRLQADT EPITKIFEDPEVTIHTSRDGRQLFEFLASKFAFKPEMVDTLYRFAKFQYECGNYSGAAEY LYFVRVLLPPNDKNALNALWGKLASEILMQDWDTALDDLNKLKDVIESALQSLQQRTWLI HWSLFVFFNHPKGRDLIIDMFLYQPQYLNAIQTMCPHILRYLTTAVITNKTVLKDLVKVI QQESYTYRDPITEFLECLYVNFDFDGAQQKLRECETVLVNDFFLVACLDDFIENARLFIF ETFCRIHQCISINMLAEKLNMTPEDAERWIVNLIRNARLDAKIDSKLGHVVMGTQAVSPY QQVIEKTKGLAFRSQMLAMNIEKKLGLR-MGVELRTIKPGDGMTFPKHGQIVVIHYTGQL PDGTVIDSSRDRNEVFKFKIGQGLVLKGWDEGIKMMSVGERAKMICSADYAYGKKGFPGV VPSNSPLIFDIEL----MPKYYCDYCDTYLTHDSPSVRKTHCNGRKHKENVRLYYQKWLE EQVQKLVDDTTAAFKAGKIQSNPFSSGGAMIPPPASL----AGP-MPMMGPGPGGPIPPM RPPHMPMGPHMPMMGPMEPLTLERDVQRAIELLENLQRSGDATKLAALQKVLQSDFCRAV REVYEHVYETVDITGSPEIRANATAKATVAAFAASEGHAHPRVVELPKTDEGLGFNVMGG KEQNSPIYISRIIPNGVACRHGGLKRGDQLLSVNGVSVEGEPHEKAVDLLKAAQGTVKLV VRYTPRVLEEMEARFDKQRSARRRQ--------------------WESRWVQSTHKGSEA GKFEWSAGKFYGDAEKDKGIQTSQDAKFYALSAKFE-PFNNDGKTLVIQFTVKHEQNIDC GGGYVKLFAKDLDQKDMHGESPYLIMFGPDICGPGTKKVHVIFNYKGKNLLTKKDIRCKD DVFTHLYTLIVRPDNTYEVKIDNQKVESGDLESDWDFLAPKKIKDPNAKKPDDWDEREKI DDPDDKKPDDWEKPEHIPDPDAKKPDDWDDEMDGEWEPPMIDNPDYKGEWKPKQKDNPAY KGKWVHPEIDNPEYKADADLYKYSDISAIGFDLWQVKSGTIFDNVLITDDEKHAEAVGEE TWGKTKDAEKKMKDAQDEDERKQ---------------------------EPSLYTVKGI VILDNDGNRLVAKYYDDQFPTAKEQKNLFNKTHRANAEIIMFEGLTCVYRSNVDLFFYVI GSAQENELILASVLNCLYDATSQMLRKNVEKKALLDNLDGVYLAIDEICDEGIILESDPT AVSQKVAIRSDDIPLGEQTVAQVIQSAKEQIKWSLLKMNIFRLIGDLSHLLAILVLLVKI WKSRSCAGLSGKSQIMFALVFTTRYLDLFTTFISVYNSVMKVIFISAAYATIYLMFVKFK ATYDSNHDSFRMEFLIVPVGGLAFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGE AETITSHYLFALGSYRALYILNWIYRYYFEGFFDLIAVVAGVVQTILYCDFFYLYVTKVW KGKKLTLPA--------------------------------------------------- ---------------------GTGKTAIALAIAQELGSKVPFCPMVGSEVYSTEIKKTEV LMENFRRAIGLRIKETKEVYEGEVTELTPVETENPMGGYGKTVSHVVIGLKTAKGTKQLK LDPSIYESLQKEKVEVGDVIYIEANSGAVKRQGRSDTFATEFDLEAEEYVPLPKGDVHKK KEVIQDVTLHDLDVANARPQGGQDILSMMGQLMKPKKTEITDKLRKEINKVVNKYIDQGI AELVPGVLFIDEVHMLDIECFTYLHRALESSISPIVIFATNRGKCVIRGT-DLPSPHGIP LDLLDRLMIIRTLPYSEEEMVQIINIRAQTESIPVHEESLQMLGSIGVKTTLRYAVQLLT PSNLLARINGKDTIMRDDIEEINDLFYDAKSSAKILQEQEDKFMKDFENDEEGDQGLLKL KEKVKKRKGRGF-TKSGVQEYEGMEV-GPGPQRSVEGWILFVTSVHEEAQEDDIIDKFGE YGEIKNIHLNLDRRTGFLKGYTLVEYETFNEAQTAMQALNGTEILGQKINVDWSFVRGPQ ANK-SYQLYRNTTLGHTLQESLDELIQCGQITPQLALKVLLQFDKAINSALATRVKNRLS FRGHLNTYRFCDNVWTFVLNDVEFRSVSKVKIVACDGRNSFLFTSESVGEGHPDKICDQI SDAVLDAHLSQDPNAKVACECASKTGMILLLGEISSKANVDYQKVVRQAIKNIGYDDSSK GFDYKTCNVLSALEEQSPEIAASVHEGRSTDDIGAGDQGLMFGYATDETEECMPLTIVLA HKLNAKIAELRRNGGLPWARPDSKTQVTCEYDLDKGACVPMRVHTVVISVQHSDTVTTEQ LRRELMEKVIKPVIPKQYLDSETTFHLNPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAH GGGAFSGKDFSKVDRSAAYAARWVAKSLVKAGLCRRALVQVSYAIGIAEPLSVFVTSYGT GVKPDPELLEIVHKNFDLRPGRIVKDLKLRTPIYQKTACYGHFGRPEFEWEKPKELKYMA GSALKRLMAEYKQLTLNPPEGIVAGPVDEENFFEWEALITGPEGTCFEGGVFSTRLTFPA DYPLSPPKMKFTCEIFHPNIYQDGRVCISILHAPGDDPMGYESSAERWSPVQSVEKILLS VVSMLAEPNDESAANVDAAKTWREDRQKFEEIAHRSVRKSLGLMRLEKCYFCSSTVYPGH GITFVRNDCKVFKFCRSKCHKAFKKKRNPRKVRWTKAFRKAAGKELVADQSLEFEKRRHV PVKY------------------------------------LRKESDIKEVQKNIHLIKSP A--MATYKVVMIRHGESQWNKENRFCGWYDADLSELGVQEARSAGEMLKEKGFKFDVAYT SVLQRAIKTLYHVQDVLQLHWIPVHRHWRLNERMYGGLQGLNKSETAAKHGEEQVKIWRR SYDTPPPVVDEASEHFPGNDPKYQLVDRNLIPRSECLKDTVARALPYWYDVIVPDVLNGK KVLIAAHGNSIRALVKYLDNMSDADIMGLNIPTGIPLVYELDANLKPIKHYYLADEEAVK AAVAKVAAQGKAKMEQTDIFYDKAEYIETASGNKVSRQSVLCGSQNIVLNGKTIIMSDCI IRGDLANVRIGRHCIISKRAVIRPPFKKFSKGVAFFPLHVGDHVMIEEDSIINAAQVGSY VHIGKNCVIGRRCVLKDCCAIADNTVLPPETVVPPFTLFSGSPGMNFLFGNRNNKTFKPK KNIPEGTHRYDLMKHAAATLGSGNLRLAVQLPDGEDLNEWVAVNTVDFFNQINMLYGTVT EFCTEQSCPVMSAGPKYEYHWADGHTVKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKI GVPFPKNFLSIAKTILKRLFRVYAHIYHQHFDQVVQLEEEAHLNTSFKHFVFFVQEFQLV DRRELAPLQELIEKLTSKD---------------KEPKSQDIYLRLLVKLYRFLARRTNG KFNKIVLKRLFMSKNNRPPMSVARLARHMKKPGRGDKTAVVVGCITDDVRILDVPKMKVC ALRVTERARARILKAGGDIITFDQLALKAPKGQKTVLLQGPRKAREAYRHFGPAPGVPHS HTKPYVRSRGRKFERARGRRASRGYKNGLKQGHIKGSYDVAKTVLLLRRLVSQKKWTNAS ELMTIVRKEGKRLIDAQPSETAVGNMVRRVLKIIREEYIIEAINELLSELETSGQALEHI HSNEVIRTVEVFLKGKFQVTVVEYEGQELATSLAKVGIETTVITDSAVFAIMSRVNKILI GTQTILADGGLKAIGSHSIALAAKHYSVPLIVCAPMFKLSPQYQCSYDDVFNKFESPQDI QNPVFDYVPPELVTLYISNIGGHAPSYVYRLLSELYHMIIPIRCFTCGKVIGNKWEAYIG LLQAEYTEGDALDALGLKRYCCRRMLLAHVDLIEKLLNYAPLEKKSPEAVEGRKHIDVQT ELYLEELSDRVEEADVECQTDAFLDRPPSPLFIPAKTGVDVATQILEGDLFDFDVEVKPI LEVLVGKTVEQSLLEVMEEEELANLRSQQRAFEELRNAELVEQQRLEEQERRHREEKERR MKQSREILRKQKETADKISARAFAQSYLADLVPSVFGTLSDNGYFFDPVERDVEQSFMPW LMERVEEQLVKIVRGRTVVDGILRDVVKARIEAYNQ------------------------ -----------------------------------------------PQKIKNFGIWLRY NSRSGTHNMYREYRDTSTTGAVTQCYRDMGARHRARTASIQVIKVEVIASSKCRRPNIKQ FHDTKIRFPLTHRVGKRLHRPRFTTRRPHTTFTAIEEMNIYWEKNLNRPQSPWLIYKLQF QSALSATHRATGLGMTIALWGIGFTALS-GVEAQTVFDTITALQVNPALMCGIKTFIVWP FFYHAFNGLRHLGWDAGKGFEMQ---------------------LSAYRDQHFKGSRSDQ ERALLESCTLYVGNLSYYTTEEQIYELFSRCGDVKRIIMGLDKYKKTPCGFCFAEYYTRK DAENGMRYVNGTRLDDRIIRTDWDAGFKEGRQYGRGKSGGQVRDEYRTDYDSGRGGYGEL FKRR-KPNYTLKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTINGH KLGISDVAWSTDSRLLCSASDDKTLKIWELATGKCLKTLKGHSNYVFCCNFNPQSNLIVS GSFDESVRTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG KWIVSGSEDNMVYIWNLQTKEIVQKLQGHTDVVLCCACHPSDNIIASAALENDKTIKLWR SDVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------SRTTTGSYVA NRVTDKLTEVTDFIYCCRSGSAADTQAITDIVKYHLNFHKMEMGEQPLVKTAASVFQDLC YNYRDSLSASIICAGWDKRLGGQVYTVPLGGMCQRQPFSIGGSGSTYVYGHVDANFKEGM TKEECLEFTANTLALAMMRDGSSGGVIRLAAITEKGVERKVFLGHELPRF---------- --------------------------------------------VQPDLDELEVNMEDNE DAESTKSEVKLGKLQFSLDYDFQKGELSVGVIQASDLPGMDMSGTSDPYVKVYLLPDKKK KFETKVHRKTLNPVFNETFTFKVPYAEIGSKTLVFAIYDFDRFSKHDQIGQVHMPLNSVD LGRVVEEWRDLTSPEADNEKENKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSD PYVKLSLMLNGKRIKKKKTTIKKCTLNPYYNESFTFEVPFEQIQKVTQIITVVDYDRIGT SEPIGRVVLGCNSTGTELRHWSDMLANPRRPIAQWHTLQEMPEKNMVLADLGRKITTALR SLSSATVINEEVLNSMLKDICKALLEADVNVKLVKKLRENVRAVIDFDEMAAGLNKRRMI QSAVFKELVKLIDPGVKAWTPTKGKNNIIMFVGLQGSGKTTTCTKLAYHYQKKGWKACLV CADTFRAGAFDQLKQNATKARIPFYGFMTKGNEQESMARLKKLMTIMDS----------- ----------------------NDTELDSHE--GARLFTRGRVQRVARGSGVSVREVQEV LTQKFAQMVKRMGGIKGLFK-GGDMAKNVQAQMAKLNSQMAKMMDPRVLQQMGGMAGLQN MMRQFQQGA--------------------------------------------------- -------------------------------------------------------PIITG LDPKTNEPFLASLDLIGCPMIPEDFVVVGTSAEQMYGMCESLWEPDLEPDDLFETISQAL MNAVD-----------------------------MTSKDYYFDSYAHFGIHEEMLKDEVR TLTYRNAMYHNKHLFRGKTVLDVGCGTGILCMFAAKAGAKKVIGIECSSIIDHAVKIVKS NGLDDVITLVKGKAEEVTLP--VEKVDIIVSEWMGYCLFYESMLKTVLFARDKWLAPGGL IFPDRATLYICGIEDRQYKDEKINWWDTVYGFDMSCIRKVAICEPLVDVVDPNQVVTNSC LVKEVDMYTIQEADLTFSAPFHLQCKRNDYIQALVTFFNIEFTKCHKRTGFSTAPDDHYT HWKQTDEYITCKKGEELFGTINVRPNNRNNRDLDFTIDIDFRGELSEMVESNHYKMRMVK EDRSTWKSNYFVKIIQLLDEYPKCFIVGADNVGSKQMQTIRASLRVLMGKNTMMRKAIRS HLETNPSLEKLLPHIKGNVGLVFTKGDLTEVREIIQNNKVAAPAKAGALAPVCVKLPAQN TGLGPEKTSFFQALSIPTKISRGTIEILNEVNLINQGEKVGASEATLLNMLKISPFSYGL QIEQVYDSGTCFDPAVLDITDEDLRSRFMEGVTNIACLSLAIGYPTIASAPHSIVSGFKN LL------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXGNEASLPMELCSTFDADEIQRLGKRFRKLDLDNSGSLSVEE FMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKESKLRFAFKIYDMD KDGYISNGELFQVLKMMVGSNLKDAQLQQIVDKTIILADTDGDGKISFEEFCAVVGNMDV HKKMVVDV----------------------QKCRFVIKYRHKDGQLLIKMTDDTVCLQYR TEHAQDVKKLEKLTSQLMRHMASKDLFEEVKLYRTGREREKYDNMADLYAVINTLQCLEK AYIKDSVTPKEYTAACSKLLVQYKAAFKQVQGDEYPTVETFTKKCKLDCPAALERIKEDR PITIKDDKGNTSKCIADIVSLFITIMDKLRLDIRAMDEIHPDMRDLMDTMNRLSILPSDF EGRAKVSGWLQTLGAMQASDELDDTQVRQLLFDLESAYNAFNRVLHSMLSSMVKEHQARQ QSRKELQEKRKKDAAAATALTHALVDHLNAGVAQAYVNQKKLDTETKILQANASHFARQT LQWLKLVEDFNQSLKEIGDVENWARSIETDMRTISSALEYAYK----------------- -------------------------------KESGAPGTVLILVAGRHKGKRVVFLKQLA SGLLLVTGPYHLNGCPLRRINQIYVIATQTKLD--------------------------- --------EEYVVSEERKQDQVEVDKQILDVVRKHPEKKFMFGYLGAMFSLKNKQYPHTM VFLEWLFGRKKTPQEMLRQNQRALKKAMRELDREKNSMEQSEKKTIAEIKKMAKAGQMDA VKIMARDLVRTRKYVKKFMIMKANIQAVSLKIQTLKSTDDMARAMKGVTKAMKSMNTQLK LPQIQKIMQDFEKESEIMDMKEEMMSDAIDDAMGDDDDEEETEAIVSQVLDELGLQMADQ LSEIPGTGSA-KKQPQAVSDADADLEARLENLKRQNNYCDFCLGDEMENKKTGQKEVLVS CADCGRSGHPTCLQFTANMIISVKKYPWQCIECKSCGLCGTSDNDDQLLFCDDCDRGYHM YCLNPPLQAPPEGSWSCHLCIEEFYGTLDRIVNLYPLTNYTFGTKEALYEKDSSVAARFK RMRDEFGRIGMRRSVEGVLIVHEHGLPHVLLLQLGTTFFRLPGGELNPNEDQVEGLKRLL TETLGRQDGAAMDWLIEDTIGNWWRPNFEPPQYPYIPAHITKPKEHKRLFLVQLPEKALF AVPRNYKLVAAPLFELYDNAAGYGPIISSLPQALSRFNFIYNFTPSGTTPTGPKAMDMAT PTPGHLLTMTPEQMQVYNWQREIDERNRPLSDEELDTMFPPGYKVLQPPAGYVPIRTPAR KLTATPTPMAGT-------XQIVDLQPKGNLPMMKPDDMQYFDRKIMKLLLKIKNGTPPM RKAALRQITDKAREFGAGPLFNQILPLLMSPTLEDQERHLLVKVIDRILYKLDDLVRPYV HKILVVIEPLLIDEDYYARVEGREIISNLAKAAGLATMISTMRPDIDNMDEYVRNTTARA FAVVASALGIPSLLPFLKAVCKSKKSWQARHTGIKIVQQIAILMGCAILPHLKNLVEIIE HGLVDEQQKVRTITALALAALAEAATPYGIESFDSVLKPLWKGIRQHRGKGLAAFLKAIG YLIPLMDAEYANYYTREVMLILVREFQSPDEEMKKIVLKVVKQCCATDGVEPQYIKDEIL PPFFKHFWNQRMALDRRNYRQLVDTTVEIANKVGAAEIVSRIVDDLKDEAEQYRKMVMET IEKIMGNLGAADIDSRLEEQLIDGILYAFQEQTTEDVVMLNGFGTVVNALGKRVKPYLPQ ICGTVLWRLNNKSAKVRQQAADLISRIAVVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLG SILGALKAIVNVIGMTKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGSEFVS AREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVC TTVAIAIVAETCSPFTVLPGLMNEYRVPELNVQNGVLKSLSFMFEYIGEMGKDYIYAVTP LLEDALMDRDLVHRQTAMAAIQHIALGVYGFGCEDALNHLLNHVWPNIFETSPHVVQAFM GAVEGMRVGLGSCRVLQYTLQGLFHPARKVRDVYWKVYNTVYIGAQDAMIPAYPRIANDE KNQYIRYELDYIL--------------------------ENQYYNSKALKEDDPKAALES FQKVLELEGNDKGEWGFKALKQMIKINFKLGNYEEMMKRYKQLLTYIKSAVTRNYSEKSI NSILDYISTSKQMTLLQNFYETTLEALREAKNDRLWFKTNTKLGKLYFDREEYGKLQKIL KQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPL IMGVIRECGGKMHLREGEYEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGIN PFDSQEAKPYKNDPEILAMTNLVSSYQNNDINEFEKILKTNRRNIMEDLFIREHIEDLLR NIRTQVLIKLIKPYTRIHIPFISKELNIDVSEVESLLVSCILDNTIHGRIDQVNQVLELD TGVAQYSALDKWTTQLQSLHQSIVNKMAVLLMGKSGSGKTSMRSIIFANYIARDTRRLGA TIDVEHSHVRFLGNLVLNLWDCGGQEAFMENYFASQRDNIFRNVEVLIYVFDVESRELEK DMHYYQSCLEAILQNSPDAKVFCLVHKMDLVQEDQRELIFRQREEDLKRLSKPLATSIWD ETLYKAWSSIVYLLIPNVQQLETNLGNFGNIIDADEVLLFERATFLVISHCQRKPHQDVH RFEKISNIIKQFKLSCSKLAASFQSMEVRNSSFAAFIDIFTSNTYVMVVMSDPTIPSAAT LINIKNARKHFEKLERVEQ----------------------------------------- ------------------------------------------------------------ ------------------AAAMISIVPGYISRSVAGSYDNEGIAIFCMLLTYAMWIKAVK TGSMFWGAMCALAYFYMVSSWGGYVFLINLIPLHVLALMLTGRFSHRIYVAYNAVYCLGT ILSMQISFVGFQPVQSSEHMAALGVFGLCQIHAFIDYVRSKLSREQFDILFRSLALISAV VIGTATGKISPWTGRFYSLLDPSYAKNNIPIIASVSEHQPTTWSSFYFDLQMLVFLFPAG LYFCFKKMTDANIFIIMYGVTSIYFAGVMVRLMLVLAPVMCILSGIAISSTLTAYMKNLD ISKKPDATYPIKNEVASGVILLTAAFLITYTFHCTWVTSEAYSSPSIVLSARAGDGGRII FDDFREAYYWLRHNTPEDAKVMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMAS TEDKAYEIMRELDVDYVLVIFGGLTGYSSDDINKFLWMVRIGGSTDRGRHIKETDYYTPQ GEFRIDKEGSSTLLNCLMYKMCYYRFGSVYTEGGKPTGYDRVRNAEIGNKDFELDVLEEA YTTEHWLVRIYKVKDLDNRG-KLNIRPLLRIMLSRFFGTFTGFTSMCVQHIPSPAANAKN KVEHIYTGPLDTELAEAMFECDPDGPLMLHTTKLYPTEDATSFHVLGRVVSGTLYANEEV KILGENYSLQDEEDSRFGQVARLWVSEARYKVEVNRVPAGNWVLIEGIDQPIVKTSTITE PTGNEEAHIFKPLKFNTSSVIKIAVEPVNPSELPKMLDGLRKVNKSYPLVTTKVEESGEH VILGTGELYLDCVMHDLRKMYSEIDIKVADPVVSFCETVVETSTLKCFAETPNKKNKITM IAEPLEKGLAEDIENEVVQITWPRKRLGEFFQTKYDWDLLAARSIWAFGPDATGPNILVD DTLPSEVDKGLLGSVKDSIVQGFQWGTREGPLCDEPIRNVKFKILDAVIAQEPIHRGGGQ IIPTARRVAYSAFLMATPRLMEPYFFVEVQAPADCVSAVYTVLARRRGHVTQDAPVPGSP LYTIKAFIPAIDSMGFETDLRTHTQGQAFCLSVFHHWQIVPGDPLDKSIVIRPLEPQPAT HLAREFMIKTRRRKGLSEDVSINKFFDDPMLLELAKQDVMLSYPM--------------- ------------------------------------------------------------ ------NGTINSAELRHLLTSLGERLTDEEVEMLLQGQDDAQGNVNYEEFVKMVLSGMSE MFFNIDNGYLEGLVRGFKGGILRQPDYLNLVQCETLEDLKLHLQSTDYGNFLANEASPLT VSVIDDKLKEKLVVEFQHIRNQALEPLSTFMDYITYSYMIDNIILLITGTLHQRAISELI PKCHPLGSFEQMEAIHIAATPAELYNAVLVDTPLAPYFIDCISEQDLDEMNIEIIRNTLY KAYLEDFYSFCKELGGATADVMCEALAFEADRRAFIITINSFGTELTKDDRAKLYPRCGK LHPDGLASLARADDYEQVKAVAEYYAEYRALFDGAGTNPGEKTLEDKFFEHEVLLMKNAF MQQFQFGVFYSYVKLKEQENRNIIWIAECVAQRHRAKIDSYIPIFSPRKTVRKISKIPFK VLDAPELQDDFYLNLVDWSSQNVLSVGLGTCVYLWSACTSQVTRLCDLSCDGDSVTSVSW SERGHLVAVGTHKGYVQIWDVTASKRVTSLEGHSARVGALAWNADVLSSGSRDRLILQRD VRTPSLAPERRLTGHRQEVCGLKWSPDHQHLASGGNDNKLFVWNMTSINPVQTYTEHLAA VKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCVDTGSQVCNLAWSKHANELVST HGYSQNQILVWKYPSLVQIAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTR STKESKSVLNMFTRIRVISFIGLYYCLTGQGFRFDIGWFLEETSPYLWANMGIGLAISLS VVGAAWGIYTTGSSILGGGVKAPRIKTKNLVSIIFCEAVAIYGIIMAIVISNQANHFAGY AMFGAGLTVGLSNLFCGVCVGIVGSGAALADAQNPALFVKILIIEIFGSAIGLFGVIVGI LQCSRAKMGDK--------------MDEDNMLVWKALIIPDKPPYDKGAFKIRIDYPTEY PFKPPKITFLTKIYHPNIDEKGQVCLPIISAENWKPATKTEQVINSLVELISSPEPEHPL RADVAEEYTRDRKKFNKKAEEFVQKFSEKRP--GASETTPQQCSALRKNGYVVIKDHPCK IVEMSTSKTGKHGHAKVHLVGIDLFSGKKYEDICPSTHNMKVPKVERKEYQVVDIA-GFV SLMEDSGELKDNLRLPVEVIKSMGTEQIMKVKAGKGRLLGPKGVAVDNNGHIIVVDNKAS CVFIFQSNGKLIHKFGSRGEHQFAGPHFCAINANNDIMVSDFHNHCVKVFDEGTFKFSFG SNGEGNGQFNAPTGVAVDKLGNILVADWGNSRIQVFDSQGSFLSYINLYGPQGLGVTSDG HVVVADSGNHCIKIYKYL----------------------KVSEAILWELFLQAGPVVNV HMPKDRITQSHQGYGFVEFMGEEDADYAIKIMNMIKLYGKPIRVNKASAHQKNLDVGANI FIGNLDPEVDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFEASDAAIEAM NGQYLCNRPISISYAFKKDSKGERHGSAA------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------MVRSGVNTVTTLIEQKKAQLVVIAHDVDPIEVVMFLPALCRKMGVP YCIVLGRVVRRKTATCLAFTQVNPEDRSGLNKLIDAVKTNFNERADEIRRHWGGGQVGAK SQARIAKLEKAKARELAQKMRYVAAYCLAKLGGNSNPTAADIKSILGSVGIEAEDDRIVK VIKELDGKDLAEVVA-------------------------------------LLTDIKAR MIFDSRGNPTVEVDVTTDKGLFRAAVPSGASTGIHEALELRDKDPKAYHGKGTFKAIDNV NKIIRPALIIPVTDQGAIDKFMLELDGTENKSKLGANAVLGVSLAVAKAGAAHKGIPLYK HLADLAGNKKVILPVPAFNVINGGSHAGNKLAMQEFMLLPTGAKSFSEAMRMGSETYHHL KSVIKKKYGQDACNVGDEGGFAPNILDNFEGLELLKEAIAKAGYTDQIKIGMDVAASEFC KKYDLDFKNPNSDKSKWLTSDQLYEVYAEFIKRYPVVSIEDAFDQDDWPAWTKMCAIQLV GDDLTVTNPKRVQKGIDEKACNCLLLKVNQIGSVTESIQACNMSRQAGWGVMVSHRSGET EDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQIMRIEEELGADAIYAGVHFRDP--PPA AGAFKKRDSKPTSFRKFYERGDFPIALEHDTKGNKIAWKVEIEKLDYHHYLPLFFDGLCE TQHPYEFFSRQGVHDMLEHGNNKILPVIPQLIIPIKNALSTRNKKVMCTTLKILQHLVIA GDMVGEALVPYYRQILPVLNIFKNNNKNSGDGIDYNQQKRENVGDLIQETLESFERTGGC DSFINIKYMVPTYESC------------------KINIQKDTKVPNAALFTVNKEDHTLG NMIRSQLLKDPQVLFAGYKVPHPLEHKFVLRIQTTPDYSPQEAFTNAITDLISEISLLEE RFAQAVKEKQE--EDHRRKWDREEYERLAKERLEAEASKKDKXIKRDLLKPREYKVDLDS KLGKSQVITKTTPAAQQGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRIERSSLD QVKKRFEMNKKKMEEKKKEYDFEERMKELREEEEKQKAYRREKRKEKKRKANEADMDPDM AAVMGFSGFGTSKKMGCTMSAEERAALERSKQIEKNLKEDGIQAAKDIKLLLLGAGESGK STIVKQMKIIHEGGFTTEDNKQFKPVVYSNTIQXLVAIIRAMGTLNIAFGDNERESDAKM VLDVIARMEDTEPFSEELLQAMKLLWVDTGVQECFGRSNEYQLNDSAKYFLDDLDRLGSK DYMPTEQDILRTRVKTTGIVEVHFHFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCV AMSEYDQVLHEDETTNRMQESLKLFDSICNNKWFTDTSEEKIKKSPLTICFPEYTGKQTY EDAAAYIQAQFEAKNKSTTKEIYCHQTCATDTNNIQFVFDAVTDVIIANNLRGCGLYYHS QFLNPPQVVGNIALLSLKTQFKGPAFDIIDEALHFFKANVFFRNYEIKSEADRTLIYLTL YITECLKKLQKCQSKNAGLKEMHTLAISTYYIPGDARFPLNAMYLKPKNRQEEDTMRAYI LQLRQECGIRLCEKVFDPSTDKPSKWWMCFAKRKFMDKSLSAPGQAGPYNYSYIFKYIII GDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVT RSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIFLIGNKSDLEAQRDVTYE EAKQFAEENGLMFLECSAKTGENVEDAFLDTAKKIYQNIQDGSLDLNAAESGVQHKPTTP RNALHTDLSQNKEGCACMVIKAVCVLKAGETTGTVHFEQTGTVTVTGEISGLAKGNHGFH VHEFGDNTNGCTSAGSHFNPHGKEHGGPGDENRHAGDLGNVVAGKVNITDSQISLTGELS IIGRTIVVHADEDDLGKGGHDDSKTTGHAGARLACGVVGIAKMVNFTVEQLRAMMDRKTN IRNMAVIAHVDHGKTTLTDSLLSKAGIIAEDHAGSKRATDTRPDEQLRGITIKSTAISMY YELSDHELRNGFLINLIDSPGHVDFSPEVTAALRVSDGAMVVVDCVSGACVQTETVLRQA VTERIKPILMMNKLDRCILEKQMDQEDLYKQLRSVIAKVNSIVDTYVDEDSPMGDLTLSP NKGNVGFGAGLHGWGFTIPQIAAFYASRMKVDEAKLTKRLWGDHFYSYTRGFNMFVLEPI YKILSTSVRREEALEMAKKVGVKLTSEQQDQHGKLLMMTIMRRWLPAGDAMFQMIILHLP SPVTAQQYRTELLYEGPLDDEAAIAIKNCDSKGPLMLYVSKMAPSPDKARFLAFGRVFSG TVGSGQKVRIMGPEYSPIKSIPRTVLMMGSSIMPVDDVPCGNLVALVGVDKYLRKTGTIT TYEHAHNLKVLKFSVSPVVRVAVEVANASDLPKFVEGLKRLAKSDPMVQITNE-NEQHIV AGAGELHLEICLKDLEEEFAGVPIKKSDPVVAYKETVSAKSRLICLAKSGNKLNRIFMTA EPLPEGLAEEIEEGKVSANQDPKERARYIVDKFGFDAAEARKIWAFGPDGHGPNMIVDCT KSVQNLQTIRDAVLAGFNWATNEGPLGEEAMRGVRFNIMDAMVHTDPACRKGGQIIPASR RCVMSSMLTASPQILEPVYLVEIQCPDTVLGGIYSTLSNRRGYIFEEVQTPGTPLFNIKA YLPVNESFGFTAALRANTSGQAFPQCVFDHWQTLIVREIRKRKGLQETIPALDNYLDKLM LPLSLLRTAVNHPMLVELKNGETYNGHLVSCDNWMNINLREVICTSRDGDRFWRMPECYI RGSTIKYLRIPDEVIDMVK----------------------------------------- ---NEFKLNNAPTDGISAVKFGPNSSQFLLVSSWDATVRLYDVHSNNMRMSYQHPTAVLD CCFHDNVHAYSGGLDNTLKMFDFNTTSETMVGTHDAPIRCVEYCPEVNVVVTGSWDSTVK LWDPRTPCSAGSFSQPDKVYTLAVCGDRLVVGTAGRRVLVWDLRNMGYVQQRRESSLKYQ TRCIRCFPNKQGYVLSSIEGRVAVEYLDPSPEVQKKKYAFKCHRVKEDGTEKIFPVNAIA FHSLHNTFATGGSDGFVNIWDGFHKKRLCQFHRYPTSIAGLAFSGDGSTLAIASSYMFEQ GPQEDAVYIRRVSDQETKPKMDFQHRAGGKTGTGGVASASESNRDRRERLRQLALETIDI NKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQANLARRAAKEAKEAPAQPAPE KPRVDIKKFVKIGRPGYKVTKQRDPESAQQSLLFQIDYPEIVEVVIPRHRFMAAYEQKVE PPDRKWQYLLFAAEPYETIAFKVPSREVDKDPKKIWTHWNKETKQFFLQFAFKHDPK--- ------------------------------------------------------------ ------------------------------------------------ENISRAIIVVQT GMTPSAKQSLTDMAPKYILEQFLESELLVNITEHQLVPEHVLMTPEEKKELLDRYKLKES QLPRIQ------------------------------------DKKDSIGTVIGIDLGTTY SCVGVFKNGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTIFDAKRLI GRAWTEKTVQQDIKHFPFKVVNKNNKPHVEVNVGSEVKLFAPEEISAMVLSKMKEIAEAY LGKKVSNAVVTVPAYFNDAQRQATKDAGIIAGLNVMRIINEPTAAAIAYGLDKKEGEKNI LVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRK SNRAVQKLRREVEKAKRALSAQHQARIEIESFYEGEDFSETLTRARFEELNMDLFRSTMK PVTKVLEDGDLQKTDVSEIVLVGGSTRIPKVQQLVKDMFNGKEPSRGINPDEAVAYGAAV QAGVLSGEEDTGDLVLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPT VTIQVFEGERPMTKDNHLLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGN KEKIVINNDQNRLSPEDIERMINDA----------------------------------- ------------------------------------------------------------ ----------EAGVEDPELEAIKQRVREMEEEAEKLKEMQTEVEKQMSMEDKIEVDSRSV YVGNVDYGATAEELEA-------------------------------------------- ------------------------------------------------------------ ----VLFETLQELAQRGGFQTLVDAVKAEKDKKARLQETILKEEEGRKRVKTLQRQLLDV KKDQEVEIQQRNEMIAHLKDQLQEMKAKTNMEGKYIKKCAEVGVSQTQKRCAMAEREMRD EIENLREKIDEETRVNAEIESYLRTHQEILGQKVDYWMEKYDKDVEAKQHELDVLKASKA KDLERLQELTKLYAEYEQVVVEDRIEKEKARRKAEQEAEELKAAVRLQSWFRGVMVRKGL GPYSKKKKKK-KVGINGFGRIGRLVMRSCLASVKVVGVNDPFIDLDYMVYMFKYDSTHGR FKGDVKLVINGQSIVVYSKMKAEEIPWDSCGAEYLVESTGVFTTKEKAGLHTKNGVKRVV ISAPSADAPMYVMGVNHENFNAEDRILSNASCTTNCLAPLAKVIHDNFGIIEGLMTTVHA YTATQKVVDGPSSKAWRDGRTAAQNIIPASTGAAKAVGKVIPALNGKLTGMAFRVPVPDV SVVDLTCRLEKGADMATIQAKVKGAMKGFLGYTDELVVSSDFIGDTHSSIFDAKAGISLN NNFVKLISWYDNENGYSSRVLDLLKYIFGRDPDDLATAILRRKERPNRLLVEEAVNDDNS VVALSQGKMDELQLFRGDTVLVKGKRRRETICIVLSDDTVADDKIRMNRCVRNNLRVRLG DVVSVQACPDVKYGKRIHVLPIDDTVEGLTGNLFEVYLKPYFLEAYRPIRKGDIFIARGG MRAVEFKVIETDPSPYCIVAPDTVIHCEGEPVKREEEEEALNEVGYDDIGGCRKQLAQIK EMVELPLRHPQLFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSK LAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQ RSHVIIMAATNRPNSVDPALRRFGRFDREVDIGIPDATGRLEILRIHTKNMKLADDVDLE QIAAETHGHVGADVAALCSEAALQQIREKMDLIDLEDESIDAEVLDSLAVTQENFRWALS KSNPSALRETAVEVPNVTWEDIGGLENVKRELQELVQYPVEHPEQFLKFGMTPSKGVLFY GPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVRDIFDKARAAAPCVLFFD ELDSIAKARGGNVGDGGGAADRVINQLLTEMDGMSSKKNVFIIGATNRPDIIDPAILRPG RLDQLIYIPLPDEKSRVQILKANLRKSPVCKDVDLEFLAKMAHGFSGADLTEICQRACKL AIRQSIEAEIQRERERAQNPDDYDPVPEISRAHFEEAMKFARRSVTDNDIRKYEMFAQTL QQSRGFGSGTNTSFGGTTVFGGATNFNPMKDIEVTSPPDDSVSSLAFSPGTLPSTFLIAG SWDNNVRCWEVQQSGQTIPKAQQTHTGPVLDVAWSDDGTKVFTASCDKSAKMWDLNSNQA MQVAQHDAPIKTVHWIKAPSYSCLMTGSWDKTLKFWDTRTPNPMMTINLPERAYCADVLY PMAVVGTAGRGLIIYQLENQPQEFKRIESPLKYQHRCVSIFVDKKSNSPVGFALGSIEGR VAIHYVNPSNPKDNFTFKCHRNGVQDIYAVNGISFHPVHGTLATVGSDGRFSFWDKDART KLKTSDQMDQPISTCCFNAQGNIFAYSSSYDWSKGHEGFDPQKMKPHVFLRSCYDELKPS SKKMSSPSPGKRRMDTDVVKLIESKHEVTILGGLNEFIVKFYGPQSTPYEGGVWKVRVDL PEKYPFKSPSIGFLNKIFHPNIDEASGTVCLDVINQAWTALYDLSNIFESFLPQLLTYPN PIDPLNGDAAAMYLHKPEEYKKKVQEYVKKYATEEALREQESSMSDFSEDEAQDMELMDE PDVLTTLKILIIGESGVGKSSLLLRFTDDTFDPEQSATIGVDFKVKTLTVDGNRAKLAIW DTAGQERFRTLTPSYYRGAQGVILVYDVTSRQSFSKLDAWLNELETFATKHEIVKMLVGN KIDKEPREVSRDQGLQFARKHHMLFIEASAKTREGVQCAFEELVEKIIQTPGLWETDGLT VGSVIWSVINGTFCSFKVRTKSQKFCRNEFNLTGLCNRTACPLANSQYATVREEKGVCYL YMKTIERAAFPARLWEKVKLSRNFEKALKQIDENLIYWPRYIKHKCKQRLIKITQYLIRI RRLTLKRQKKIVPLSRKVERREKRREEKALVAAQVDTAIEKELLDRLKAGTYGDIYNFPS HAFDKALEEEEVSEEEESEPEIEYVAEDEVEESDLSDLEVLQTRLAQQERLKTFNIYRWN PDKPGDKPHMQSFSVDLNTCGPMVLDALIKIKTEQDPTLTFRRSCREGICGSCAMNIAGC NTLACLCKIDDNTSKPTKIYPLPHMYVMKDLVTDFNNFFAQYRSIEPYLKKKDVKEADIG REPYYQSMEDRAKLDGMYECILCACCSASCPSYWWNGDKYLGPAIIMQAYRWIMDSRDDF TEERLDQLRDKYSVYRCHTIMNCTRTCPKGLNPGAAIGEMKKLLGGYQSQGIPR------ --------------------LYAIFSQFGQILDIVALKILKMRGQAFVIFKDINSATNAL RSMQGFPFYDKPMRIQYAKKDSDMIAKIKGTFVERPKRKKQPEPKRKRKQQAPATIPEQP PNQILFLTNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENEIQSAAAKEALQ GFKITPTNAMKISFAKKMDSQGRKVIVCDNGTGFVKTGYAGTNFPEHIFPSLVGRPILRS TAKIGNIEVKDLMVGDEASQLRSMLEVNYPMENGVVRSWEDMIHLYDYTFGSQKLNINPR ECKLLLTEPPLNPTKNRQKMVEVMFEHYQFDGLYVAIQAVLTLYAQGLLTGVVVDSGDGV THICPVYEGFALPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMMKEKLCYV GYDIDQEQKLALETTVLVESYTLPDGRVIRVGGERFEAPEALFQPHLINVEGFGVAELLF NTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLEREIKQLYLERVLKGDTAKLSKFKIR IEDPPRRKHMVFLGGAVLADIMKDKDTFWMTRQEYQEKGLRCLEKLGVSMSETAGKPIQC RAAVAWEAKKPLSIETIEVAPPKAGEVRLKVLATGVCHTDAYTLDGFDPEGKFPCVLGHE GGGIVESVGEGVTSVKPGDHVIPLYIPQCRECKFCKSPKTNLCQKVRTTQGAGVMPDGTS RFTCKGQTLAHFMGTSTFSEYTVVAEVSVCKVADNAPLDKVCLLGCGISTGYGAALNTAK VEAGSTCAVWGLGAVGLASIMGCKVAGATRIIGVDINPDKFETAKQFGATECVNPKDYDK PIQQVLAEMTDGGLDYTFECIGNVATMRAALEACHKGWGTSVIIGVAAGGQEIATRPFQL VTGRVWKGTAFGGWKSRDSVPKLVDEYMEGIVKVNEFISHDLPLDKINEAFDLMHTGKSM DSYDVIANQPVVIDNGSGVIKAGFAGDQVPKYHFPNFIGRPKHVRVMAGALEGDTFLGPK AEEHRGLLTIRYPMEHGVVKDWNDMERIWQYIYSKDQLQTFAEEHPVLLTEAPLNPRRNR EKAAEIFFETFNVPALFISMQAVLSLYATGRTTGVVLDAGDGVTHAVPIYEGFAMPHSIM RVDVAGRDVTRYLQLLLRKEGHNFHTSAELEIVRTIKERACYLSINPQKEETMETEKSQY TLPDGSILEIGPARFRAPELLFRPDLIGEECEGIHEVLAFAIQKSDMDLRRVLFSNIVLS GGSTLFKGFGDRLLSEVKKLAPKDIKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKR EYDEEGVRAVHRKTF-----------PLVLLSVVDHFNRMGKVGNVKRVCGVLLGANKSG QLDVSNSFAVPFDEDEKDKSVWFLDHDYLESMYGMFKKVNAREKIVGWYHTGPKLHQNDI ATNELMRRYCPNSVLVIIDAKPKDLGLPTEAYIAVEEVHDDGTPTSKTFEHIPSEIGAEE AEEVGVEHLLRDIKDTTVGTLSQRITNQLMGLKGLNSQIQDIHSYLEKVVQGKLPINHQI IYHLQDVFNLLPDVNLMEFVKAVYVKTNDQMLVVYVASLIRSIIALHNLINNKIQNRDAE KNEGKDKKMGLLFTKLWSLFTNEEHKVIIVGLDNAGKTTILYQFLMNEVVHTSPTIGSNV EEVVWKNIHFLMWDIGGQESLRSAWNTYYTNTEFVILVVDSTDRERLTITKEELYKMLAC EDLKKAAVLIFANKQDIKGAMSAAEISQQLNLTSIKDHGWHIQACCALTGEGLYQGLEWI TNHIRRRSIPSRRVIINDPSQLPSQYSTTPGGTIFSTTPGGTRIIYDRAFLLQCRNSPLT KSPPCNLPKIPGVTSPPPPGKRKEIYKYEAPWTLYSMNWSVRPDRRFRLAVGSFVEEYNN KVQIVSLEEETSEFTSRSTFDHPYPTTKIMWIPDTKGVFPDLLATSGDYLRVWRATRLEC LLNNNKNSDFCAPLTSFDWNEVDPNLLGTSSIDTTCTIWGLETGQVLGLVAGHVKTQLIA HDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLAWNKQ DPNYLATMAMDAMEVIILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQAL IWDIQQMPRAIEDPILAYTASGEINQIQWSSTQPDWIAICYNNCLEILRV---------- ----------------------------------GVAADISHCSTRAKVTGFLGPEQLRQ SVEGCDVVVIPAGVPRKPGMTRDDLFNTNASIVRDLTDACAQFCPKAMICVISNPVNSTV PIASEVFKKRGVYDPNRIFGVTTLDIVRANMFVAEAKGLDVNKVNIPVIGGHSGVTIIPL ISQGTPPVSFPQDEREALTTRIQNAGTEVVEAKAGAGSATLSMAFAGARFVNSVLEALNG EEGVVECAFVRSDETEAKYFSTPLLLGKNGVEKNLGLGKLLEFEVNLIKKAMPELKANIA KGEEFIAKNIDRGKDFNIKTRIITDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFAS TLSHLRRLNSPIGRDGKLARPRQLHNTQWGMICPAETPEGAAVGLVKNLALMAYISVGSQ PSPILEFLEEWSMENLEEIAPTAIADATKIFVNGCWVGIHRDPEQLMNTLKKLRRQMDII VSEVSMVRDIRDREIRIYTDAGRICRPLLIVENQKLLLKRRHIDLLKEREYNNYSWQDLV ASGVVEYIDTMEEETIMLAMTPDDLQEKGVAYCSTYSHCEIHPAMILGVCASIIPFPDHN QSPRNTYQSAMGKQAMGVYITNFHVRMDTLANVLFYPQKPLVTTRSMEYLRFRELPAGIN SIVAIASYTGYNQEDSVILNESAVDRGFFRSVFFRAYKDAESKKGLDQEEVFEKPNRDHV QGMRHAVYDKLDEDGIIAPGTRVSGDDVLIGKTLTLPENEDELEGKVQQYSKRDTSVFMR RSETGIVDQVMVTINQEGYKFCKVRVRTTKTPQIGDKFASRHGQKGTCGIRYRQEDMPFT NEGLTPDIIINPHAVPSRMTIGHLIECLQGKVSANKGEIGDATPFNDTVNVQKISQLLYE YDYHLRGNEVLYNGHTGRKMNSQIFLGPTYYQRLKHMVDDKIHSRARGPVQILNRQPMEG RSRDGGLRFGEMERDCQIAHGAAQFLRERLFEVSDPYRVHVCNICGMIAIANLRNSTFEC RGCKNKTQISQIRLPYACKLLFQELMSMSIAPRMMT------GGFSFENCRRNALLENGF KPPKVYKTGTTIVGVVYKDGVVLGADTRATEDTIVADKNCSKIH---------------- ------------------------------------------------------------ -------------------------------------------VRNAIAGGIFNDLGSGS NVDLCVITKKVDYIRPYDEANQKGKRQGSYRYKRGTTAVISENVKKVEVEVV-TKVTFKI TLTSDPKLPYKVLSVPEQTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPAQSAGNVFL KHGSELRLIPRDRVGH---------------------------IIAFDELKTDYKNPIDQ CNSLNPLVLPEYGLHIFFNLLFLLSWQWGTLLLNTPLIAYHINRYLHRPVMSGPGLYDPT TIMNADQLNRAQREGWIKLAFYLLSFFYYLYSMIYVLVSSMGLLTILKKMKQKEKEIRLL MLGLDNAGKTTILKKFNGEDIDTISPTLGFNIKTLEHRGFKLNIWDVGGQKSLRSYWRNY FESTDGLIWVVDSADRRRLEDCRQELEALLLEERLSGATLLVFSNKQDLPGALSPTDIQE ALQLDNIKTHHWLIKGCSAVTGENLLTGIDWIIDDIASRIFTMD---------------- -----------------HNLLLNYGLYRKMEIYRPQKATYDEMTKFHSEDYIRFLRSIRP DNMSDYNKQMQRFNVGEDCPVFDGMYEFCQLSTGGSVAGAVKLNKQAADIAINWAGGLHH AKKSEASGFCYVNDIVLAILELLKYHQRVLYVDIDIHHGDGVEEAFYTTDRVMTVSFHKY GEYFPGTGDLRDIGAGKGKYYAVNFPLRDGIEDDSYELIFQPVMSKVMEMYQPSAVVLQC GADSLSGDRLGCFNLSLKGHGKCVEFIKKYNLPLLLLGGGGYTIRNVARCWTYETSMALA VDIANELPYNDYFEYYGPDFKLHISPSNMANQNTPEYLDKIKTRLFENLRMLPHAPGVQM QAIPEDALNDDVNPDERISIRASEKRITCDEEFSDSEDEGEGGRRDRQSYRRERKDNRSF ECNICLDTAHDAVVSMCGHLFCWPCLHQWLETRPNRQVCPVCKAGISKDKVIPLYGRGSA NQQDPREKLPPRPPGQRTEPENSGGFPGFGFGFQMSFGIGAFPFGFFASTFNFNDGRPQA PAAGTPQHSEEQFLSKVFLWVAVLFIFWLLIA---------------------------- ----------------------------GHQLGVVSVDINISGVLAASSSLDSHIRVWDL ETGKQVKSIDAGPVDAWTIKFSPDSRFLASGSHTGKINLFGVETGKKESSLDTRGKFTLS IAYSPDGKYIACGAIDGIINIFDLTTGKLLEGHAMPIRSLCFSPDSQLLVTASDDSHIKI YDVQHANLAGTLSGHGSWVLNVSFCPDNTHFVSSSSDKTVKVWDAASRQCVHTFFDHLDQ VWCTTYNTSGTKIVSVSEDRALHVYDCPVESDEEFDARYEAFFNNPEIDGWDIRRGINDL QAMDLVPEPRIISAALKACRRVNDFALAVRILEAVKDKCGAR-KDIWPYIVQEIQPTM-D LGIDSLEKLGYDKPELAAKDVWDMV----------------------------------- --------------------------------KRYIEVFKSKRSEMDWVVKRSGSNQDAV VRLRGLPFGCSKEEIAHFFSGMEIVPNGITLIHDGQGRTTGDAYVQFASQDIAESAQQKH KEKIGHRYIEIFKSTLAEARANYVSQTGHCVHMRGLPFAANEQDILDFFAPLNPVNVVIH FNEGRASGESDVDFATHEEAKEAMKKDKAAMQHRYIELF--------QIRRSNITAAKAV ADAIRTSLGPRGMDKMIQSGAGDVTITNDGATILKEMQVLHPAAKMLVELSKAQDVEAGD GTTTVVVVAGSLLDACQKLLTKGIHPTTISESFQKAATKATEILGSMSTQLELSDRESLL KSATTSLNSKVVSQYSNILSPITVDAVIKVIDPATATNVDLRDVKIVKKLGGTVEETELI DGLVFNQKSTGIGGPNKIEKAKIGLIQFCISPPKTDMQNQVIVSDYTQMDRVLKEERKYI LDIVKQVKKAGCNVLLIQKSILRDAVNDLALHFLAKMKIMVVKDIEREDIEFVCKSLNCK PVASVDHFTPEALGSAELVEEVQTGTSKVVKITGIANPGKTVTILVRGSNKLVLEEADRS IHDALCVIRCLVKKRALIAGGGAPEIEVALRLHDYANTLTGMEQYCFKAFAEALEVIPFT LAENAGLNPIATVTELRNRHAKGEKTAGINVRKGAITNILEENVVQPLLVSTSAIHLASE TVRSIMKIDDIVNC-MILLEINNRIIEETLNLKFENALGGNKPELVDITIADFDGVLYHI SNPDGDKTKIRVSISLKFWKDLQEHGADDLIQREYGSYLTSPEDGYNVSLSYSDNVPKDY KDVVKKAGLLKRNCFASVFEKYFEFQSKHKRAVIHYRDDETMYVDARKDRVTVIFSTVFK DDDDIIIGKVFMQEFKEGRRNYQQAPQVLFSHKEPPLELSQTDAKTGDNIGYITFVLFPR HENQDNTINLIHTLRDYLHYHIKCSKAYIHSRMRAKTSDFLKVLNRARPEPKNVEKKTIM LMFCPVCANVLIAEEGPKCYRFACNTCPYVHNVTRKISNRKYPKLKEVDDVLGGAAAWEN VDSTEETCPKCRHDRAFFMQIQTRSADEPMTTFYKCCNMSCGHRWR-------------- ---YGRHDWRLKGAMARGDYYKTKEILLKGHEWILKEIVASGLRGRGGAGFPTGMKWGFM NKPDDGRPKYLVVNADEGEPGTCKDREIMRHDPHKLVEGCLVAGRAMGARAAYIYIRGEF YNEASNMQVAINEA---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------FTQEQVD EMNQQLNQTRSQRVRAAMFPETLEEGIQIPSTQIHPDQPTAVQRLSEPSQMLKHAVVNLI NYQDDADLATRAIPELTKLLNDEDQVVVSQAAMMVHQLSKKEASRHAIMNSPQMVAALVR AMSNTNDVETTRCAAGTLHNLSHHRQGLLAIFKSGGIPALVKLLSSPVESVLFYAITTLH NLLLHQEGSKMAVRLAGGLQKMVALLQRNNVKFLAITTDCLQILAYGNQESKLIILASGG PGELVRIMRSYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGMHLGHQSQRLVQN CLWTLRNLSDAATKQDGLEGLLQMLVQLLSSNDINIVTCAAGILSNMTCNNQRNKVTVCQ VGGIEALVRTILQAGDREDITEPAVCALRHLTSRHPEAEMAQNAVRLHYGLPVLVKLLHP PSRWPLIKAVVGLIRNLALCPANHAPLREHGALPRIVQLLIRAHQDTQRTQGGYVDGVRM EEIVEGTVGALHILAREAHNRAVIRGLNCIPLFVQLLYSPVENIQRVAAGVLCELAAEKE GAEIIEQEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRGD A------------------------------KSKNSFRYNGLVHRKTVGIEAASDGKGVV LVTRKNWRKPAKAFTRTELKKGSRRTLNTLRKVLRNNRYRKDLKKGSRRTLNTLRK---- -------DEPYYCSAQINIPPELPDILKQFTKAAIRTQPKDVLGWSAAYFRALANGETPP VKERLEMPVATQKTDTGLSPGLLRVLNKQLGPRKTVDLSVIEEKWKDLALPKEQFDELVR IGSFGGNVEWIKFFSLACSALGENITDAMKTVCEILTADPDGGPARIPFQLFKDLYKYLA TVDGEISQEHMDEVINHLQYDVDKQEGMVQPRNFLSPDCPSLSGKIDAAQRDNLMESVKA QIAVANAQELLQKMSDKCFKKCVYKPGTSLDSSEQKCIAMCMDRYMDAWNIVSKTYATRL QRERSKM----------------------------------------------------- -------VKQKALRVLKQKRVYEQQRDNLMQQSFNVEQANFSIQSVKETKQVVDAMKVGV KEFKKEYKKVXIDDIENVQDDLEDLMEQANEVQEIMGRSYGMPEVDDEELEAELDALGDD IALDEDASYLDEASAAPNAPTSIPGADSVTNKDGVPVDEFGLPQLPS------------P QLQNIVCTVNLGCKLDLKKIALHARNAEYNPKRFAAVIMRIRDPRTTALIFSSGKMVCTG AKSEDQAKLAARKYARIIQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHGQFSSY EPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKVRKEIYEAFENIYPILKGFKKQDDEDD DEFVDMGMEPEPSSKHDVEEFPFEVLTTEQIVQHMVDCIKEVNAVVEIPATITRILLNHF KWDKEKLMERYYDGDQDRLFSEAHVISPHRKPTEVICEICYMLLPSMMTGLECGHRFCTQ CWTEYLTTKIMDEGMGQTIACAAHGCDILVDDATVMKLVTDPRVKLKYQQLITNSFVECN RLLRWCPTPDCGHAVKVTCYDAKPVTCVCAHTFCFACGENWHDPVKCKWLKKWIKKCDDD SETSNWIAANTKECPKCQVTIEKDGGCNHMVCQHCKADFCWVCLGPWEPHGSSWYNCNRY DEEEAKKARDAQEASRAALQRYLFYCNRYMNHMQSLKFEHKLYASVKQKMEEMQQHNMSW IEVQFLKKAVDVLCQCRQTLMYTYVFAFYLKKNNQSIIFEENQKDLENATEQLSEYLERD ITSDILVDIKQKVQDKYRYCESRRKVALDHVHEGYDKDLWEYQ-MATTDGKLSTTDRIIK GVPFPPSHRLTMSEVFDQKGKPKPDVLKQHFIVEGRVTEDVALRIINEGAALLRQEKTMI DIEAPVTVCGDIHGQFYDLMKLFEVGGPPATTRYLFLGDYVDRGYFSITERVYDACMEAF DCLPLVALMNQQFLCVHGGLSPEIHNLDDIRKLDRFKEPPAFGPMCDLLWSDPLEDFGNE KTTEHFSHNSVRGCSYFYSYAACCDFLQQNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSL ITIFSAPNYLDVYNNKAAILKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVT EMLVNVLNICSDDELMSEGDDTFE----ARKEIIRNKIRAIGKMGLEF------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TKIEYRAWNPFRSKLAAAILGGVDNIHMGPGAKVLYLGA ASGTTVSHVSDIVGPEGLVYAVEFSHRSGRDLINVAKKRTNIVPIIEDARHPHKYRMLVG MVDTIFADVAQPDQARIVAINAHHFLKNTGHVVISIKANCIDSTAAAEAVFAGEVTKLRE EKIKPREQITLEPYERDHAVVVGQYRPPPKKMDGKKLGDLAGRLQKGGKGAGIGLGFLAA AGGAVYALSQSFYTVDGGHRSIIFSRIGGVQPDIYKEGLHFRVPWFQYPIIYDIRSRPKR ISSPTGSKDLQMVNISLRVLSRPDAAMLPHMYRQLGTDFDERVLPSICNEVLKSVVAKFN ASQLITQRQQVSLMIRKELTERARDFNIILDDVAITELTFGREYTAAVEAKQVAQQEAQR AQFIVERAKQERQQKVVQAEGEAKAAKMIGEAIHTNPGYLKLRKIRAAQSISRTIAASKN RVYLNAGSLMLNIGEKEFDEMLE------------------------------------- ------------------------------------------------------------ ------------------------------------IDKCMNHENWQPNMILDDGGDATH LMLKKYPAMFSLVKGIVEESVTGVHRLYQLSKSNKLTVPAMNVNDSVTKTKFDNLYSCRE SILDALKRTTDVMFGGKQVVVCGYGEVGKGCCAALKGLGAVTMVTEIDPICALQACMDGF RTVKLQEVVRQVDIVITCTGNKNVVTREHMDRMKNGCIVCNMGHSNTEIDVNGLRTPELT WEKVRSQVDHIIWPDSKRIILLAEGRLVNLSCSSVPSFVVSVTASTQALALIELFNAPPG RYKQDVYLLPKKMDEYVASLHLPSFDAHLTELSDEQAKYLGLNKAGPFKPNYYRYPDPDA IKMFVGQIPRSMDENDLRKMFEDFGPIYQLNVLRDKITGQSKGCCFITFYTRKSALDAQN KLHNIKTMPGMQHPIQMKPADSEKRNVEERKLFVGMLAKKCNENDCRMMFSPFGTIEECT VLREQNNQSKGCAFVTYASRQCAQNAIKAMHHSQTMEGCRSPLVVKFADTQKEKEMKKIQ QMNNALGVQ-----------------------------------FDCAKKIFLKEGPTGF YKGMAAPLIFAVCFWGFNV-GKRIQIAGVFTTSIMAPGERIKCLLQVCAKQLYKEGGIRS VYKGTAATLLRDVPATGMYFMSYEYLQNILTPEGGSRKDMSPRTIFAGGMAGICNWLVAM PQDVLKSRLQTQKEGPKALYKGFTPVMIRAFPANGCCFLGYELAMKFLTDSSNEFTRLSQ VIGNNIQKITQNVAQMQRMVNQIGTQQDSPDLRDRLHQVQHYTNQLAKDTTKYLKDLAHL SSDQKQRKIQKERLMNDFTQALNNFQTTQRNVAEKEKASMEDVDLDLLREREQAIFQLEQ DITDVNQIFKDLGMLVHEQGEMIDSIEANVESVHVQEGTQQLSKARDYQSKARRKKCIII IIVIIVLAVIATIIGVTVSMVNVMKGVLVECDPAMKQFLLHLDETNALGKKFIIQDLDET HIFIASDMVEFLQDRIDELMDKLSFPMGKKKDQAPTAQEAIQKLRETEEMLEKKSDYLEK KIAQELGTAKKRAALMALKRKKRLEKQLQQIDGTLSTIEFQREALENASANSEVLKNMGY AAKALKAAHQQLDVDDVHDLMDDIQEQNELAEEIGQALSQPAGFGQDVDEDELLAELEEL EQEDLDEKLLDVANLPDVPRAEDDDMKELAAWASSMQRFHNRVRQILMASGSTTFTKIVN KWNTALIGLMTYFREAVVNTQELLDLLVKCENKIQTRIKIGLNSKMPSRFPPVVFYTPKE LGGLGMLSMGHVLIPQSDLRWSKQTDVGITHFRSGMSHDEDQLIPNLYRYIMPWESEFID SQRVWAEYALRTDMIQALGGVEGILEHTLFKGTYFPTWEGLFWEKASGFEESMKYKKLTN ASKDTMDNATTQKYWLDIQLRWGDYDSHDIERYARAKFLDYTTDNMSIYPSPTGVLIAID LAYNLHSAFGNWFPGAKPLIQQAMAKIMKANPALYVLRERIRKGLQLYSSEPTEPYLSSQ NYGELFSNQIIWFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSV WAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKG SELQLPFQACLKVEKFGDLILKATEPQMVLFNLYDDWLKTISSYTAFSRLILILRALHVN NDRTKIVLKPDKTTITEAHHIWPSLSDDEWIKVEVQLKDLILADYGKKNNVNVASLTQSE IRDIILGMEITAPSAQRQQIAEIEKQTKEQSQLTATTTRTVNKHGDEIITSTISNYETAT FSSKTEWRVRAISATNLHLRTNHIYVSSDDIKETGYTYILPKNVLKKFIIISDLRAQIAG YIYGVSPPDNPQVKEIRCIVMPPQWGTHQTVHLPNMLPGHEYLKEMEPLGWIHTQPNELP QLSPQDITTHAKVMSDNPGWDGEKTVVITCSFTPGSCSLTAYKLTPSGYEWGRQNTDKGN NPKGYLPSHYEKVQMLLSDRFLGFFMVPGQGSWNYNFMGVRHDPNMKYELQLANPKVFYH EIHRPSHFLNFSSLEEGTDREDLY----ATRQNLNVNKDTRVICQGFTGKQGTFHSTQAI EYGTNMVGGVSPGKGGSKHLDLPVFNSVQEAKDATGATATAIYVPPKFCAAAIIEAIDAE MPLVVVITEGIPQQDMVKVKQRLLKQSKTRVIGPNCPGIIRPGECKIGIMPGHIHQRGKI GIVSRSGTLTYEAVHQTTQVGLGQTLCVGIGGDPFNGTNFIDCLDVFVKDPKTEGIVLIG EIGGRAEENAAEFLKEHNGPNRKPVAAFIAGLTAPPGRRMGHAGAIISGGKGGAEEKIEA LKDAGVEVTMSPAQMG------------PSSEALKCTLCHERLEDTHFVQCPSVPEHKFC FPCSRESIKRQGAGSEVYCPSGKKCPLVGSNVPWAFMQGEIATILG-------------- -----GKLVAIVDILDQNRALVDGPCTGVARKIMNFKQLHLTKYVXISHSMRPGLVKKAW ERDQIS---------------EKRKELTDYDRFKLMKAKQARNRLINVEVGKMLX---KT CPLLLRVFCSTGRHNPMSEYSRGNTPANELQIYTWMDATLKELTSLVKEVNADARKKGTF FDFAIVFPDNRTPTYRLREIGTTCAGRKGQDDATTLASKRFNIGDYLDIAISPPRGLGKT LQTISLIGYMKHYRNIPSPHLIIAPKSTLANWMAEIERWVPTLRGVCLIGDQEKRAAFVR DVLMPGEWDVCVTSYEMCIREKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKSANR LLLTGTPLQNNLHELWALLNFLLPDVFNNSEDFDAWFNTNSCFENNVLVERLHEVLRPFL LRRIKSDVEKKLLPKKETKIYIGLSKMQREWYTKILMKDIDVVNGAGKSDKMRLLNILMQ LRKCCNHPYLFDGAEPGPPYTTDQHLADNCGKMVLLDKLLPRLKAQDSRVLIFSQMTRML DILEDYCYWRGFNYCRLDGQTPHEERQASINEFNAPNSEKFVFMLSTRAGGLGINLATAD IVILYDSDWNPQVDLQAMDRAHRIGQTKQVRVFRFVTDNTVEERIIERAEMKLRLDNIVI QQGRLVDQATNKEVLNMIRHGADHVFASKDSEITDEDIDAIMARGEKKTEELAQKMSKLG ESSLRSFTLDTPDSSVYQFEGQDYREKQKHSGIGHWIEPPKRERKANYAVDAYFREALRV SEPKAPKAPRPPKQPNVQDFQFYPPRLFELLDREIYYYRKNIGYKVPKNPEFGVDAERIR KEEQEKIDEAEILTDDEIAEKEELLKGFTNWSKRDFNQFIKANEKYGRDDIESISKEVEG KTPEEVMEYSSVFWERCNELQDIEKIMAQIERGEAKIQRRISIKKALDAKMARYRVPFHQ LRIQYGTNKGKNYTEEEDRFLVCMLHKLGFDKENVYDELRTSVRQAPQFRFDWFIKSRTA MELQRRCNTLITLIERENLELEEKEKAERKKDSKPSWADQVELGEDRELPPLHEDFDENN GIKKITEYKMNDEGKKVKIVKTYKIEVRKVSKTIAKRKMWHKFGAAAGDPPGPNPANTIE DVFMVFIHNKDQQDEDPLNKLKVSCRICKGDHWTTRCPYKDTLGPVEEGAAKPGKYVPPS LREGGPRRGESMQPDESATIRVTNLSEDTRESDLQELFRPFGTISRIYLAKDKNTGQSKG FAFINFHRRDDAARAIAGLSGYGYDHLILNVEWAKPSMSETYDFLFKFLVIGSAGTGKSC ILHQFIENKFKQDSNHTIGVEFGSKVVNVGGKSVKLQIWDTAGQERFRSVTRSYYRGAAG ALLVYDITSRETYNALTNWLTDARTLASPNIVIILVGNKKDLEAEREVTFLEASRFAQEN ELIFLETSALTGENVEETFLKCARAILAKLESGELDPERMGSGIQYGDASLRRLQPRRPE CSC---------------PLLLKHFDKLNIKTTHYTPIPSGCSPLKRPIDDYVRSGVINL DKPANPSSHEVVAWIKRIFEVSKTGHSGTLDPKVTGCLIVCVERATRLVKSQQSAGKEYV CIFRLHSAVENEKKIYQAVETLTGALFQRPPLISAVKRQLRVRTIYESKMIEYDKERNMG IIWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGIQSEKDGLVTMHDVLDAQWLYD HHKDEAYLRRVIKPLEALLVSHKRIILKDSAVNAVCYGAKIMLPGVLRYDDGIEVNDEIV VITTKGEAVALAVAQMTTAVIVSCDHGMVAKLKRVIMERDTYPRKWGLGPKASMKKEMIK SGLLDKYGRTNEKTPKEW------------------------------------------ ---QMRSQQAINAAQRQGVTIETEKKYAGGQNKQHSANKNTAKLDRETEELHHSTIGLDV GRLIQQGRQAKNLTQKELATKINEKPQVINDYEAGRAIPNQQVLGKLERAIGMKLRGKDK GKPLVPGMLKPKALTQVLSQANTGGVQSTLLLNNEGALLAFSGYGDKDARVTAAIASNIW SAYEKHGKAAFNEDKLQYVLMECEEGRVAITRVANLLLCIYAKESVGFGMLKAKAKALAE YLEEPLTQVAAS----------RQTLDDAYAIPANFLEIDVCSPEGKNRYTDYEVRMKTN LPVFKVKESCVRRRYSDFDWLRQELERDSKIVVPKLPPKAIFKQLPFRSDDGIFEEEFIE ERRKGLEEFVNKIAGHPLAQNERCLHMFLQEPVIDKNYVPGKIRS-RFLSARLAEVGILE TPKLQGKYDTGQLFLHRVFGYRGVVLFPWVGKVYDRDIASKGSKEVKGRTHTYYQVLIDS RDIPHIRVGTESVTFLSNQENGTLYSIPGLDYVGHEDILPYATTEKQPIHNHLFDKFLAL DNKFMAKNTLREWQLKNHPWLELTDVHRETTENIRVTVMPFYIGEVQQTPVYWWRYCIRL ENLGDETVQLRERHWRIFSLSGTLETVRGRGIIGKEPVFSKSQPAFQYTSHVSLQAPSGH MWGTFKMEREDGSSFECRIPPFALESKHEDS----------------------------- --------------ECKICARPFTVFRWCPGARMRFKKTEICQTCAKLKNICQTCLLDLE YGLPVQVRDAALKIQDEMPKSDVNKEYYTQNMEREIANSDGTSPVGALGKAQAPSDLLLK LARTTPYYKRNRPHICSFWVKGECKRGEECPYRHEKPTDPDDPLADQNIKDRFYGINDPV ADKLMRRYNNMPKLEPPED----------------------------------------- -----------------------APATIGMTFREFENLEITPLSTPPELPDVMKSPETAS HQPE-HLYRYHAVLLRARFDENKDIDMRKAKQLLQDGEHELFLKQHPQPMRFPHSPGGVS HGREPHSPDWLLDMWHPFEKAQYPEYFARREQRKKEFIERWEKQYGPAQ----------- EGTYGVVYKGKNKKTQRTVALKKIRLESEEEGVPSTAIREISLLKELQHPNIVCLEDVLM QENKLYLVFEFLSMDLKKYMDSIPSGQYM-----------------FCHQRRVLHRDLKP QNLLIDSNGVIKLADFGLARAFGIPVRVYTHEVVTLWYRAPEVLLGSARY---------- ------------------------------------WPGVSSLPDYKPTFPAWRNNTLNN SVDSTGLDLLQKMLIYDPAVRISAKAALNHPYFAVRFLNNLGKIGLGLAVAGGVVQTALY NVDGGHRAVIFDRFSGVKETVVGEGTHFLIPWVQRPIIFDIRSRPRNVPSLTGSKDLQNV NITLRILFRPIAARLPGIFTNLGIDYDERVLPSITNEVLKAVVAEFDASELITQREMVSQ RVNEELTNRAESFGLILDDISITHLTFGKEFTEAVELKQVAQQEAEKARYLVEKAEQQKL AAVIAAEGDSQGAVLLAKAFAEAGDGLVELRKIEAAEDIAYQMSQSPNIVYLPQGQQTLL SLP--------------------------------------------------------Q WFGIRHELAAVRTVCSHIENLIKGVAKGFRYRMRSVY------------DTLVEVRNFLG EKYTRRVRMLNGVTCSNSTSQKDELILEGSDIERVSRSAALIQQSTTVKRKDIRKFLD-- -----------MGICVSSEDKLASERSKQIDKTLRADGEKASREVKLLLLGAGESGKSTI VKQMKIIHEKGYSTEECMQYRPVVYSNTIQSMVAIIRAMGQLKIDFGHADRADDARQLFA LAGNAEDGELSADLAGIMKRLWKDSGVQSCFARSREYQLNDSAEYYLNALERISQPNYIP TEQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFIVAMSE YDLTLAEDQEMNRMMESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLSICFPE YQGSNTYEEAAAYIQVQFNKRKDTKEIYTHFTCATDTNNVQFVFDAVTDVIIKNNLKDCG LF-------------------------KRKKADPQNMKIRELPQASSALFFKYNTQLGPP YHVLIDTNFINFSIKNKLDVVQSMMDCLYAKCVPYITDCVMAELEKLGSKYRVALRIAKD PRFERLSCMHKGTYADDCLVQRVTQHKCYIVATCDKDLKRRIRKIPGVPIMYLSQHRYSI ERMPDAFGAPKMSFSSDEVNFLVYRYLQESGFAHSAYTFGIESHISQSNINGALVPPAAL LSIIQKGLQYTEAEISIGEDGAERVIETLSLIDAVMPDVVESRKQASTKNTNGEEHTEEM EIDGTVEIPSSKATVLRGHESEVFICAWNPTNDLLASGSGDSTARIWNMNDNSNANQLVL RHCIQKGGTEVPSNKDVTSLDWNCDGTLLATGSYDGFARIWSTDGRLVSTLGQHKGPIFA LKWNKKGNHILSAGVDKTTIIWDASSGHCTQQFAFHTAPALDVDWQSNISFASCSTDQCI HVCKLGVDKPIKTFQGHTNEVNAIKWDPQGTLLASCSDDMTLKIWSMQQDSCVHDLQAHS KEIYTIKWSPTGPGTNNPNASVILASASFDSTVRLWDVDRGSCIHTLTRHQEPVYSVAFS PDGKYLASGSFDKCVHIWNVHSGALVHSYRGTGGIFEVCWNHRGDKVGASASDGSVFVLD LRKSNNDLAQLFECPVCFDYALPPIMQCQSGHIVCSSCRPKLTCCPTCRGPLGNIRNLAM EKVASTVMFPCKYASSGCPETLLHTEKSEHEETCEFRPYCCPCPGASCKWLGSLEQVMPH LMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHNFMLVLEKQEKYDGLQQFYA IVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHDGVQSAIINSDCLVFDTNIAQLF ADNGNLGINVTISMC--------------------------------------------- ----------------------------------------EEGSFRGRTADFFFMFLFGG TLMTVTVNLVFLGQAFTIMLVYIWSRRNPYVRMNFFGLLNFQAPYLPWVLLGFSLLLGNS IVVDLMGIAIGHIYYFLEDVFPEQPGGFKILKTPGFLKWILDPVREDPNYNPLPPGGFNW GEGLELLSDQGFRIDGRRPNELRRIQCRMGVFGQADGSAYIEQGNTKVLAAVYGPHEVRG SKSKHDKVLINC------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MSGNYYFGI VGHHDNPVFEMEFVPPNKASEPKKDDHRHLNQFIAHAALDLVDEQMWMTSNMYLKIVDKF NEWFVSAFVTAGRMRFIMLHDMKNEDGIKNFFTEMYETYIKLSMSPFYEPNSAIKSAAFE KKAQFYGRKYL--QVRYAHTDIQIPDFSDYRRPSVAASRKSFTYMMVAAGSIPTAYAAKT LVTEFVSSMSASADVLALVKIEIKLEDVPEGKNVTFKWRGKPLFVRHRTAEEIETEQSVN IAELRDQQHDSDRVKKPEWLVLIGVCTHLGCVPIANAGHFGGYYCPCHGSHYDASGRIRK GPAPLNLEVPEYEFPDDSSLVVGMARQGTRGADPRKVSGELFTLTYGALVSQLLKDYEND EEVNKQLDKMGYNIGVRLIEDFLARSSVGRCHDFRETADVIAKVGFKMYLGTTPAVTNWS AAGDEFSLLLENNPLTDFVELPEGHNNLNYSNILCGVLRGALEMVQMEVDVRFTQDHLKG DNITEIRLKFVKRLEDAVPAGED---KQFLAQAREEFNQKWENPQQDTACLDDFERIKTL GTGSFGRVMLVQHKATTKYYAMKILDKQKVVKLKQVEHTLNEKKILQAISFPFLVSLDFS FKDNSNLYMILEXVEGGEMFSHLRRIGRFSEAHSRFYGSQIVLALEYLHSLEIMYRDLKP ENLLINTQGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVY EMAAGYPPFFADQPIQIYEKIVSGRVRFPSHFSGDLKDLLRNLLQVDLTKRFGNLKNAVN DIKNHKWFSTTDWIAIYQKKVEAPFTPRCKGPGDPSNFDDYEEEPLRISQTEKCAKEFAD FMIADTLLILFISVATAFLGEGLTWLLVYRTDKYKKLKAEVEKQSKKLEKKKEA-GESAD RGHKKKIERQEEKLKNHNRDLSLVKMKSMFAIGFAFTALLSMFNSIFDGRVVAKLPFIPI YWLQGISHRNLGGEDYTDCSFIFLYILCTMSIRQNIQKMLGFAPSRAANKQGGGLFGT-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------LTGHTGSVLCLQYDENIIISGSSDSTVRVWSVKTGEMLNTL IHHCEAVLHLRFCDGIMVTCSKDRSIAVWDMQSPTDINLRRVLVGHRAAVNVVDFDEKYI VSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACL RVLEGHEELVRCIRFDSKRIVSGAYDGKIKVWDLHAALDPRAPAGTLCLRTLVEHSGRVF RLQFDEFQIVSSSHDDTILIWDFLNMAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNS TFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKS FENIRNWIRNIEEHASQDVEKMVLGNKCDMNDRRQVSKDRGEQLAIEHGIKFMETSAKAS INVEEAFFSLARDIKAKMDRKL-DGESSADRNVEIWKIKKLIKSLEAARGNGTSMISLII PPKDQISRVAKMLADEFGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPGNGLVIYCGT IVTDEGKEKKVNIDFEPFRPINTSLYLCDNKFHTEALTALLADDNKFGFIVMDGNGALFG TLSGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAEVAVQLFITNDRP NIAGLVLAGSADFKTELSQSDMFDPRLQAKILKIVDVSYGGENGFNQAIELASEALANVK FIQEKKLIGKYFDEISQDTGKYCFGVVDTLKALEMGSVEILIVWENLDIQRYVLKNHQTD EEKILYLKPEQEKDKTHFTDKETGVEMELVDSQPLLEWFANNYKSFGATLEIITDKSQEG AQFVKGFGGIGGILRYQVDFQGLEAYDDLVDDWDPDEYITRCSQPLVG----XDERYIQM IMDANAQSHKLYIMDARPSVNAVANKAKGGGYESEDAYPHAELIFLDIHNIHVMRESLRK LKDICFPTIDDTHWLSNLESTHWLEHIKQILAGAVRMADKVENNKTSVLTHCSDGWDRTS QLTALAMVMLDPYYRTIRGFEVLIEKEWLSFGHKFGQRIGHGEDKHSDADRSPVFLQFID CVWQMTKQFPNAFEFNEHFLISILDHLYSCLFGTFLHNSEQQRVKEDLKNRTVSLWSYIN CQLEEFTNPLYQHVLFPVASMRRIELWTGYYIRWNPRMRPQEPIHLRNRELLILKAQLQK RVDELQRELDAKN---RTFIPHVPFDLVQCESAFPRAKPAADDKAFTDALLKRNQDLTPA AQEQSAVLNLATKVNTVIDNLIINPGAFDAAVIEEVRQVGSHKKGTMMAGHNVADIVVIL KTLPTVEAVQALGNKVIEDLKASDPQEVLSMLTNESGFEISSSEATVKVLITTIPPNLKK LDPELHLDGKIMQGHLAAIRHARWFEENAFHSSIKVLIRLLRDLKNRFEGFEPLTPWIIE LLAHYGIMSNPTRQPLAINIAFRRCLQL-------------TDPCESGNTRVHTVMTLEQ QDQVCYTAQTLLRVLSHGGYKQILGIEGNASIATEMSVWEGVVVTPSDKAYEKPEK---- ---------LFRTLTVLQEESGISLNTVDSVDSFVSDINNGHWDTVLQAIQSLKLPDQKL IDLYEQIVLELIELRELGAARSLLRQTDPMIMMKQQQPDRYLHLENMLARSYFDPREAYP EGQTKERRRAAIAQALSGEVNVVPPSRLLALLSQALKWQQHQGLLPPGTSIDVFRGKAAV REQEEEKYPTQLSKTIKFGQKAHIECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLK YQAQDNFMMMDDAVLCMCFSRDSEMLATGGQDGKIKVWKIGTGQCLRKFERAHSKGVTCV SFSKDNSQLLSASFDQTIRIHGLKSGKTLKEFRGHTSFVNDVVFTPDGHHILSASSDGTI KLWNIKSTECQNTFKSLGGTSAGEITVHSVHPLPRNVEQFVVCNRSNTVVIMNMQGQIVR SFSSGKREGGDFVCATVSPRGEWIYCVGEDMVLYCFSIHTGKLERTLTVHEKDVIGITHH PHQNLVSTYSEDGLLKLWKP------KVPQLANFAQPKLSTFWKYARVELRPPGELPQVQ RDIQSMVVARTGKWKNITAKEAALVTAEVAFWFFIGECIGKGSIVGYQVPGATHFDL-TI PKFYFKLPSEDELLLQKLREESRAVFLQRRSRELLDNDELQGLWFLLDKHHTPPLVGDEQ MINYEDFLKVGAQAGEKCQPFFTATVFAKLLQTDPYGRISIMQFFNYVMRKVWLHQTRIG LSLYDVAGQGYLRESDLENYILELIPTLPQLGGLEESFYSFYVCTAVRKFFFSLDPLRTG KVKIQDILACSFLDDLLELRDEDLSKDMQETNWFSAPSALRVYGQYLNLDKDHNGMLSKE ELARYGTGTLTDVFLDRVFQECLTYDGEMDYKTYLDFVLALENRKEPQALQYLFRILDVQ NKGYLNVFDLNYFFRAIQEQMKLHGQEPVSFHDVKDEIFDMVKPADPYKITLQDLIQSGH GDTVLSILIDLNWFWTYENRETEVVRGQMFDVGPRYKTLQYIGEGAYGMVVSAIDTHTNN KVAIKKISPFEHQTYCQRTLREIKILTRFKHENIINIQDIIRASTIEEMKDVYIVQCLME TDMYKLLKTQKLSNDHVCYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFG LARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDVWSVGCILAEMLSNRPIFP GKHYLDQLNHILSVLGSPNQEDLSCIINDKARSYIQALPFKSCVPFSKLADHKALDLLGK MLTFNPNKRITVEESLAHPYLEQYYDPQDEPTADEPFTFETELDDLPKEKLKELIFEET- -----ELSPPKTTPEWVKFCKQLFGGFAILLWIGAILCFIAYSIQASTFEDPPGDNLYLG IVLTAVVVVTGCFSYYQEAKSSRIMESFKNMVPQFAIVVRSGEKLNIHAEELVLGDLIEV KFGDRVPADIRIISAHGFKVDNSSLTGESEPQVRTAECTSENPLETRNLAYFSTNAVEGT ARGVVVSTGDNTVMGRIANLASGLEMGQTPIAKEIAHFIHIITGVAVFLGVSFFIIAFIL GYDWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTI CSDKTGTLTQNRMTVAHMWFDNQIVEADTSDDQSNATYDRDSPTWMALARIAMLCNRAEF KVNQENVPVLKRECNGDASESALLKCVELSIGNVSSFRASNEKICEIPFNSTNKYQVSIH NNDPRNLLVMKGAPERILDRCSTIYIHGEEKPLTEEWREAFNQAYLELGGLGERVLGFCD YILPADQFPIGYPFDADEENFPLTGLRFVGLMAMIDPPRAAVPDAVGKCRSAGIKVIMVT GDHPITAKAIAKGVGIISEGNETVEDIAARKGTSVQNIQPSEAKACVVHGSDLRDMTPAQ IDDILAHHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIA GSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLLFIIAD VPLPLGTITILCIDLGTDLVPAISLAYEQAESDIMKRMPRDPVNDKLVNQRLISMAYGQI GMIQASGGFFTYFVIMAENGFWPGRLLGIRKEWDSKGTNDLEDSYGQEWTYAQRKVLEYT CHTAFFVSIVIVQWADLCICKTRRNSILHQGMSNHRLTFGLFFETTLAAFLAYCPGLDKG LRMYPLRWSWWVAPMPFSVIIFIYDEVRKYILRRNPGGWVEEETYYSFRNLTKGKKVAAS LTAGGIGLGVALHELELHPPHFPWTHAGPFSSFDHMSIRRGYQVYKQVCAACHSMNYLCY RNLVGVCMTEEEAKMEAEEVQVTDGPNDEGEYFERPGKLSDRFPKPYANDEAARAANNGA LPPDLSYITSARHGGEDYVFSVLTGYCDPPTGVELAEGQYYNPYFPGGAIGMAQALYNEI IEYDDGTPATQSQLAKDVCTFLRWAAEPEHDDRKRMGLKAILFFLIAIAYYVKRHKWTVL KNKKLAWIRPDVPSRCTYSTSKLTESPHRHIKRRPKILPNILHMIGETPLVRINNIGKSF GLKCELLVKCEYFNAGGSVKDRIGLRMIEDAEKDGTLKPGDVLIEPTSGNTGIGLALAAA VKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTSASFDSPESHIGVAQRLLNEIPNAHI LDQYRNASNPLAHYDSTAEEIIDACDGRMDMIVVGAGTGGTLTGISRKIKEKFPEAKVIG VDPEGSVIAVPDDTSFYEVEGIGYDFVPTVCDRQFVDKWYKSGDKESLKMARRMIKEEGL LCGGSSGAALSCAIKAIKHYDL--------------------------------XXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMP DIMRLITKDLSEPYSIYTYRYFIHNWPKLCFLAMQGKKCVGAIVCKLDMHKKMVRRGYIA MLAVDDQYRRRKIGSHLVMKAIKAMVADDCDEVVLETEISNKAALRLYENLGFVRDKRLF RYYLNGVDALRLKLWLR------------------------------------------- ------------KDDATKGKFAFTTEEYDMFEVCFETKMPGGGQGADREIFLNMKHGAEA RDYAAIAKAEKLKPLEVELKKLEDLSESIVNDFAYMRAREEEMRDTNESTHSRVLYFSIF SMCCLLGLATWQVLYLRRYFKAKKLIEEMESGRTSSVGNDILGFQGKVVNKPEHGNLDWI KICEQASKVITFIDLAGHEKYLKTTVFGMTGHAPDFSMLMIGANAGVVGMCKEHLGLALA LNVPVFVVVTKIDMCPPNVLSDTLKMLQRILKSPGCRKIPVLVQNEDDVICTATNFTSER MCPIFQVSNVSGENLPLLKMFLNLLSTRISGEPAEFQIDDTFSVPGVGTVVSGTTLKGVI RINDTMLLGPDALGQFMPIAVKSIHRKRMPVKEVRGGQTASFALKKSQIRKGMVMVSPRL EPKACWEFEGEILVLHHPTTISCRYQAMVHVGSVRQTATIVAMSMEHLRTGDKAIVRFRF IKNPEYLRTDMRMVFREGRTKAVGNVTKLFPHVSANTRQQRAAKKAAEQEKLSQIDDHTF YLFKVLRAHILPLTNVAFNKSGSCFITGSYDRTCKVWDTASGEELHTLEGHRNVVYAIAF NNPYGDKIATGSFD----------------------------------------DTTAKL WDVICTLNGHSAEIISLAFNTTGDQLITGSFDHTVSVWDKRIHTLIGHRAEISSAQFNWD CSLIATGCMDKTCKIWDASTGQCIGTLRGHDDEVLDVCFDYTGQYLLT------------ ----XHEGEISKICFNPQGTRILTASSDKTARLWDPETGECKQILEGHTDEIFSCAFNYE GSTIITGSKDNTCRIWRGDVFMEKHWKSVIHRSICDYFFEAQGKAGSPEDVLPVIATPHH YLINIYRNSLYLVAVTTTEAPPLFVIEFLHRCLDIFEDYFTECTESIIKENYKIVYELLD EMLDNGFPLATESNILKEMIKPPNLLRTITDTVTGKSTSVSATLPTGQLSNVPWRRTGVK YTNNEAYFDLIEEIDAIIDRSGSTVFAEIQGYIDCLIKLSGMPDLTLSFVNPRLLDDVSF HPCVRFKRWENERVLSFVPPDGNFRVISYHIGAQNMVAIPVYLKHSISFKDGSSGRLDIT VGPKQTMGKPVENVVLEIPFPKAVLNVTLTPNQGKYSFDPVTKLMTWDVGKIDTTKLPNI KGTINLQSGAPPPEANPTISVQFTINQMAVSGLKVNRLDMYGEKYKPFKGVKYVTKAGKF QVRTMATYVKPATRYATSDWYTSNYAISTNAERQRSASHDIRQEGRFLRNETDNKTAWDQ ADNNTRLSDRILNIRKWKDILEKTLADTEKEIADLSEAKENTEVALESMNLPTDVNIENL VTREGRQNIDVVEDEVEDQLHKEKQVIDGIKKQLQQKIAEGTEQLHLLQEARQQLLLDLQ DKNIALEIDVDQYNLTEESPGISFKPDPLRVPKGSTTPQNWEDFSRYNKDRAEAEMNASR HLREAIHHTIQQTRNDLDAQQTATDYAYRRRMHDMKKAIDELNWQKQQTEEEIAELENDI RGLNDKIRAKINPMKLAQTRLENRTYRPNVELCRDNVQYGLTDEVKQLEASKQALEEKLR QSQHALHQLEQNLHRINEDLQCKTNSLKLDENCMLSRAKMEKNLSLTGV----------- ------------------------------------------------------------ ------------------------------------------------------------ VHPMAQFSAAITACSSESKYSKAYAEGVHKAKYWEYVYEDSMDLIAKLPTIAAIIYRNLY RDGTSVGAIDPDKDWSANFVSMLGFENPDLAEVMRMYLTIHSDHEGGNVSAHTCHLVGSA LSDPYLSFAAGMNGLAGPLHGLANQEVLVWLQKAKLSEAHLKEFIWNTLKSGQVVPGYGH AVLRKTDPRYVCQREFALKHFPNDPMFTLVSNLYKIVPDILLEQGKAKNPWPNVDAHSGV LLQYYGLKEMNYYTVLFGVSRALGCLASLVWDRALGLPIERPKSMSTEGLVKLAQMPFKP VQTEKCTICTKSVYAAERQEAGKRIYHKNCFKCSVCKMPLNLNNYAQAEGILYCKNHYAS EVVAKNAQIDQLFVHRDSAENNPELTFEFTAENKKRADAIISNYPKGHEAAAVIPLLDLA QRQNGWTSIPVMHYVADLLKMPKMRVYEVATFYTMFNRTPVGKYHIQICTTTPCMLGGVG SDVIVDAIKRKIGIGLGETSKDKMFTLTEVECLGACVNAPMVQINDNYYEDLTVKDIEEI LDDIKAGKVPKAGPR---SGRFACEPAGGLTSLTTPPYAPDFKVRSDLMQKYEKLEKIGE GTYGTVFKAKNKESHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHS EKKLTLVFEYCDQDLKKYFDSCNGEIDPDAVKSFMYQLLRGLAFCHSHNVLHRDLKPQNL LINKNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIF AELANAGRPLFPGNDVDDQLKRIFKLLGTPTEDTWPGMIQLPEYKPYPMYNVNQQVVPKL NAKGRDLLLNLLICNPARRMSAEDGMQHLYFSDLNPAIK-DSKFFTYDGPRDDINYPISG EC-SMPVEYCEYHPSYDRCKKWMEKNLPEELQQMLLKRQSRGGRGVIKARKKTEPQQVSL FRANRGKKKYVTVICGLATYEIDLKDASKYFANKFSCGSSVTGEDEIVIQGDVKDDLFDL ITEKWPQISEDNI----------------------------------------------- -------------------HCMPETIAHCKDCGKLQTMDILLRKLKSGQHRVLIFTQMTR MLDVLEAFLNYHGHRYLRLDGTTRVEQRQALMERFNMDKRIFCFILSTRSGGLGVNLTGA DTVIFYDSDWNPTMDAQAQDRCHRIGQTRDVHIYRLISEKTVEENILKKANQKRLLGDVA IEGGNFTTAFFKQQTIKEL----------MSLETVPKDLRNLRACLLCSLVKTFDQFEFD GCDNCEEYLHMKNNRDAVYDCTSSSFDGILALMSPEDSWVAKWQRINRFTKGCYAVSVTG RLPPGIIRELKSKGISYRSRDTS------------------------------------- ------------------------------------------------------------ ----PGIKVDKGVVPLAGSDGECTTQGLDGLNERCAQYKKDGAQFAKWRCVLKISTHTPS FQAVAENANVLARYASICQQNGLVPIVEPEILPDGDHDLETSLKVTEQVLSFVYKALADH HVFLEGTLLKPNMVTPGQSCSKKYTPQQVAEATVLALQRTVPPAVPGITFLSGGQSEEDA SIHLNAMNQRPWALTFSYGRALQASVLAAWGGKPENVAAAQQELLKRAKANGDAALGKYT GGAAGAAGASQFVADHAY---NLPKVVKRRIKALKKLQFEMIKIESKFYEEVHELECKYA EKYAPLYERRKEVVTAGVEPTDSDCDWPSD-EEETEKVKVEEEENPNGVPNFWLTIFKNV DMLSEMVQEHDEPILQHLQDIKVKFSMGFKLEFYFEPNEYFTNTLLTKEYILRAEPEEGD PFSYEGPEIVKCTGCTIDWQKGKNVTVKLIKKTQKHKGRGTKRTVTKTVQNDSFFNFFSP PEIAEGEADEDTEALLAADFEIGHFIRERIVPRAVLYFTGEALDEEEEDENEE--IILLK EGTDTSQGKPQLISNINACQAIVDAVRTTLGPRGMDKLIVDAQGRATISNDGATIMKLLD IVHPAAKTLVDIAKSQDAEVGDGTTSVVLLAGEFLKHCKPFIEEGVHPQIIVRAFRKATA LAVQKIKEIAVTIKKDPKEQRQLLEKCAATALSSKLVAHQKDFFAKMVVDAVMLLDELLP LSMIGMKKVQGGALEDSRLVAGVAFKKTFSYAGFEMQTKKYNNPKIALLNVELELKAEKD NAEVRVDSVEEYQSIVDAEWKILYDKLEKIHLSGANVVLSKLPIGDVATQYFADRNMFCA GRVPEEDLKRTMKACGGSIQTTTANLELGRCELFEEEQIGGERYNIFTGCPESKTCTIIM RGGTEQFIAETERSLHDAIMIVRRAIKNDSIVAGGGAIEMELSKYLRDYSRTIAGKEQLL IGAMAKALEVIPRQLCDNAGFDATNILNKLRQKHAGTWYGVDIMTEDIADNFHACVWEPS VVKINALTAASEATCLILSVDETIKNPKAQDAPAGRGRGRGRPMKRNNLIPNGHFHKDWQ RWVKTWFNQPARKARRHNNRVKKARKIMPRPVGGPLRPVVRCPTFKYNSRIRAGRGFTLE ELKAAGINKRQAPTIGIAVDYRRRNKSVESLQQNVQRLKEYKSKLILFPKKLSNPKTGDA TAEELKTATQLSGE-MPIIQVHKKEKARKITEEEKKYSAYTALRQARANARLFGLREKKA REAMPNIKVFSGTSHPDLAQKIADRLGIELGKVVTKKFSNQETSVEIGESVRGEDVYIVQ SGCGEINDGLMELLIMINACKIASACRVTAVIPCFPYARQDKKDKSPISAKLVANMLSVA GADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENIPEWKNSIIVSPDAGGAKRVT SIADRLNVEFALIHKERKKANEVAAMVLVGDVKDRVAILVDDMADTCGTVCHAAEKLLEA GAMKVYSICTHGIFSGPAISRINNSMFECVVVTNTIPQDDKMKGCSKIQCIDISMILAEA VRRTHNGESVSYLFSHVPL----------------------------------------- -------------------------------------------------------EKFAK AKCVNSILRHVGELLNYETDEQLEELYQKTAWAFDRKYNKAGASYEAFKHAVANPEILDE LDLDEETKKMLLSNIRRRLTPQAVKIRADIEVACYGYEGVDAVKSALRAGLSLTTEDMPI KINLIAPPLYVMTTQTLERAEG-------------------------------------- -------DPKTYKQHFENKHPKAPMPEVLLEV------------------------CDKV IVGQVITALGKIWHPEHFVCVQCGDELGTRNFFERDGQAYCERDYHNMFSPRCAYCTGPI LDKCVTALDKSWHPEHFFCAQCGRTFGDDGFHEKDGKAYC--DYFEMFAPRCGGCAQPIM DNYISALNHQWHPECFVCRECRIPFGGGSFYDHDGMPYCETHYHAKRGSL---------- -----------------------------------------------RPLTDEETKTFFE KLSKYIGDNIRLLLDRPDGTYCFRLHKDRVYYVSEDIMKRACNVARDNLMSFGTCFGKFT KSSKFRLHITALDYLAPYAKYKVWLKPSAEQQFLYGHHVMKSGLGRVTENTPQYQGVIVY SMADLPLGFGASAKSTQECRHADPMTIVVFHQADIGEYIRSEETL--------------- --------------------QIGVAAQNCYLEYVRGKLIGVAAQNCYKVEKGAFTGDISP AMIKDVGCEWVILGHSERRHVFGESDELIGAKVKHALEAGLHLIPCIGEKLEEREAGKTN DVVFTQTKATDWSRVVLAYEPVWAIGTGKTATPEQAQQVHQDLRQWLRTNVSAQVADSVR ILYGGSVNAKNCKELASKPDIDGFLVGGASLKPEFNTIINAREREGLLDPAWEKQQRKTF TAWCNSHLRKAGTQIDNIEEDFRNGLKLMLLLEVISGEQLPKPDRGKMRFHKIANVNKAL SYIESKGVKLVSIGAEEIVDGNVKMTLGMIWTIIVQNFHLSFKDGLAFCALIHRHRPELI DYNKLSKDNPLENLNTAFDVAEKYLDIPKMLDPEDMVASAKPDERSVMAYVSSYYHAFSG AQQAETAANRICKVLKVNQENERLMEEYERMASDLLEWIRRTTPWLENRSTDNTLPGTQR KLEEFRDYRRKHKPPKLEEKARLETTFNTLQTRLRLSNRPAYLPTEGKMVGDIANAWKGL ETAEKGFEEWLLSELQRLERLDHLAQKFKHKCDIHEEWSYGKEDMLQAQDFKQCRLNELK ALKKKHEAFESDLAAHQDRVEQIAAIAQELNALDYHDVTTVNTRCQRICDQWDLLGTLTQ TRRTGLEEAERVLERIDQLHLEFAKRAAPFNNWMDGAKEDLVDMFIVHTTEEIQGLIDAH EQFKQTLGEADKEYNAIITLVQEVQRYVQQYGIYGATENPYTTLSAQDIANKWTEVKQLV PKRDTTLQQEMIRQQNNERLRRQFAQKANVVGQWIERHLDAVASV-MQRGSLEDHLNKLK TVEKEVMAYKPNMDELERFNQDVQEAMIFENRHTPYTMETLRVGWEQLLTSVARNINEVE NQILTRDSKGISDQQMDEFRKSFFHFDKNRTRRLEPKEFKACLVSLGYNIRDDKQGEADF QRIMSITDPNHTGYVTFDAFLDFMTRETTDTDTAEQVMQSFKILAGDKPFITADILRREL PPDQAEYCIQRMAPYGGRDAAPGALDYSSFSTALYGESDLNKLGITSVDVKDKRVLIRVD FNVPLKGSEITNNQRIVAALPTVKHALEKGAKSVVLMSHLGRPDGRRQDKFTLAPVAAEL KKLLGKDVQFLNDCVGPEVESACANPAPGSVILLENLRFHIEEEGKGVDTEGKKVKAKED DVKKFRASLSKLGDVYVNDAFGTAHRAHSSMVGVELPQRAAGFLLKKELDYFSKALGTPE RPFLAILGGAKVADKIQLITNLLDKVNSMIIGGGMAYTFLKVHNKMEIGTSLFDAEGAKI VEDILKKAAEKGVTIQLPQDFTTADAFKEDANAGTATVAEGIPAGWMGLDCGPKTVAESK ALIAKAKTIVWNGPVGVFEFDKFATGTKAVMDAVVEVTSKGATTIIGGGDTATCCAKWGT EDKVSHVSTGGGASLELLEGKTLPGVAALSDA---------------------------- ---------------RRGYYNGIKFHRIIRDFMIQTGDPTGTGRGGASIYGKEFDDEISD ELKHAGAGIFSMANSGPNTNGSQFFITLAPTQWLDGKHTIYGRVSSGMQVVNRVGLLETD NNDRPQEDVKILKHRSRSRERNRSRSPKSKRKPYKYWDIPPAGFEHITPMQYKAMQAAIP FAGSAISRQARRLYVGNIPFGVTEEMMMDFFNTQMHLAGFAQAEGNPVIACQVNLDKNFT FLEYRSVDETTQAMAFDGIIFQGQALKIRRPRDYQPLPGMAETPSVGVVSTVVQDSPHKI FIGGLPNYLNEDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDQACAGLNGMQLG DKKLIVQRASVGAKNAQQAPVQIQIPGLNLNQ-ATEVLCLMNMVAVEELEDEEEYEDILE DVKEECGKYGVVRSIEIPRPITGIEVPGCGKIFVEFNSIIDCQKAQQALTGRKFANRVVV TSYYDPEKYHRREFFIPLFDRVLIERLAAETKTKSGLVIPEKAQAKVLEGTVVAVGKGAR SSKGDIIPPSVQVGDRVLLPEYGGTKVNFEDKEYLLLRDADLLGK--RLKTQIPDIKTSL DIVKHMKSKKAPIETQFMLSDQLYAKATIPPSEKVCLWLGANVMLEYDLEDAEALLVKNT ATKSLEQVDDDLGFIRDQTTTIEVNMARVYNWDVKRRQAEKG------------------ ---------------------------EFQKIVGSFIEVVDNVAKEVEKEKMKAIGSRNQ LKSIAKQREAQQQQLQALIAEKKMQLERLRVQYEALQKEEAEQSEFIEQFILQK------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GFGFVTFHDAEDAKKALEQLNGF ELAGRPMKVGHVTERTAEASVLDSDEMDRAGIDLGATGRLQLMAKLAEGTGFQIPQVAAN ALNMSGATAAPPIATQCFMLSNMFDPTGSNMRWDVEIRDDVIEECNKHGGVLHIYVDKAS PQGNVYVKCPSIAAAVASVQALHGRWFGGKVITAAYVPLPNYHALFPEATRANQLLLPST DEREDEISPIP-HHPKPRNRRGAVSAEVYTEEDAASYVKKVVPKDYKTMAALSKAIAKNV LFSHLDDNERSDIFDAMFPVHRHAGEVIIQQGDAGDNFYVIDQGEVDIYVNTEWVSVIGD GGSFGELALIYGTPRAATVKAKTDIKLWGIDRDSYRRILMGSTIRKRKMYEEFLSKVSIL ENLDKWERLTVADALEPVQFEDAQEIVRQGDQGDDFFIITEGAASVLQRRSENEEPVEVG KLGPSDYFGEIALLLDRPRAATVVARGLLKCIKLDRGRFERVLGPCADILKRNIAQYNSF VSLSVASYKGLAKLNRLLYIADHALAYVMTTFNTNMYQQIHRKLQEAITSNVPALDTQWI ETTAKKAALKLEKLDTDLKNYKSNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDY CTSAKHVVNMCLNVIKVSMYLQNWSHVLSYVNKAEATPEVTEGKDGGQAVITKLKCAAGL AELATKKYKSAAKYFLQASFDHCDFPELLSANNVTMYGALCALASFDRAELQKNVISSSS FKLFLELEPQLRDILHKFYESKYASCLRLLDEIKDNLHLDMYLAPHVNTLYTQIRNRALC QYFSPYLSADMNKMATAFNTTLAAMEDELMQLILDGQINARIDSHNKILYAKDIDQRSTT FEKSVAMGKDYQRRTKALILRSAMIKNQLHVKSPPRDGGQGAEMSIAPGTAAS------- ---------QVLRHGKHVLPHIARLCLISTFLEDGIRMWFQWNEQRDYIDATWGCGWFLA TMFVIVNLIGQLGACIMVLSRQKVNIACGILFGIIALQTVAYSILWDLKFLMRNLALAGG VILLLAESKAEGKSLFAGLPSLGENTPKTYMQLSGRILLVLMFLTLLRFELAFLQLIQNL VGTALIILIAVGYKTKLSALILVVWLTILNLYFNAWWNIPDYKPMRDFLKYDFFQTLSVV GGLLLVVALGPGGYSMDEHKKKWRQTVTLIPGDGVGPELTQSIKDIFSAAGVPVDFEELF VSRNGVGLKGIISSPLETLNMKIRRSLDLFANVVRIRSLPGFTTKHNNLDFVVIREQTEG EYSSLEHESVKGVVESLKIITREKSRRIAKFAFDYATKHGRSKVTAVHKANIMKLGDGLF LECCAEVAALYPKIKFENMIIDNCCMQLVSNPHQFDVMVMPNLYGNIVDNLAAGLVGGAG VVPGESFSHNVAVFEPGARHSFPTAVGRNVANPTAMLLCACNMLKHMNLEFHGTQIQQAI EKVIKAGKVRTKDMGGYSLTSDFTAAVIKNLSEEFQRFIDRSARIVERALYEDINIFADY GGADTDEGLAEGEKLKLNRQFYDERWSKHRTITCMDWSSQHPELLVASYNCNEEAPHEPD GVALIWNIKYKKPTPEYIFHCQSAVMSTCFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPV QRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKMCSWSLDMLSQPQDSMELQHKQSK VAVTSLSFLSGDVNNFVVGSEEGAVYTACRHGSKAGIGEAFEGHQGPITGVDCHAVPGQI DFSQYFVTSSFDWTVKLWNIKENRPLHSFEDNSDYVYSVRWSPIHPALFASVDGMGRLDL WNLNNDTEVPTATKYNVALNRAEWHPTGHNIAVGDDMGKIHIYDVGEPVAVPRNDEWSKF MHTLSDLKNNRAEQMEEHVEQQLLQAAKVVEQQVDAEIERLDKMDDDDFEALQQQRLQQL KKAQNQKKEWLTLGHGRYEEIATEKEFFDVCKKSKNVVCHFYRDSTFRCKIVDKHLEILA PKHIETKFVKLNAEKCPFLVERLRIVVLPTICLAKDGKTVDYIVGFDDLGGSDEFPTEML EWRIARGDVINYSGDLLTPPGTDHQKKNIRGRDDSD---------GIRMVKVQNKPTPKE GEVLVKVKACGLNFSDLVVRQGAIDNPPKTPFVMGFECAGEIVALGENVENYAVGDKVIA LSNAWAELLAHVFKMPSGMSFQDGAALCMNYVTAYVMLFDIGNLRKGQSVLVHSAGGGVG HAVCQLCKTVEDITIFGTASYKHDSIKNN-LTHLFDH-VVDYCQEIRKVSPEGVDIVLDS LCGDDTNKGIGLLKPLGRYILYGSANIVTGETKSFFSFAKSWWQVDKVNPIKLYDENKTI SGFNLRQLMIVNKLFKMYTEGKIRPQVDSAWAFEDVGDAMQKMHDRKNIGKVLLDPSL-- ----------------------------GVLACLDGYMNIALEQTEEYVNGQLKNKYGDA FIRGNNVLYISTQKRRI---SRAALLLKQQLAELTKNPVTGFSAGLVDD-DLFLWEVLII GPSDTLYEGGFFKCHLTFPKDYPNKPPKMQFMSEIWHPNIEKTGEVCISILHDPGEDKWG YEKAEERWNPVHTVETILISVISMLSDPNDESPANIEAAKDWRENMTEFKRKVARCVRKS QE-TVRPVNPLLHQTLTDFGRYVGECLPKFVQKAEVQNGDELEIMIHPDGIIPVLTFLRD HHNAQFTNIVDICALDVPTRQYRFELVYNLLSIHHNARIRVKTYTDELTPVESSCSVYHG SNWYEREIWDMFGVFFANHPDLRRILTDYGFEGHPFRKDFPLSGYVEVRYDDEVKRVVVE PIELAQEFRKFEFSSPWEAFPAFREE---------------------------------- ------------------------------------------------------------ ------------------------------------------------QLPSNRFLQPVH KCDMALTDLLGELQRDPWPVAQGRRPLRSTGVALSIAVGLLECTYPNTGARIMLFMGGSC TQGPGMVVGDELKHPIRSHHDIEKDNCKYMKKAMKHYESLANRAAANGHIIDLYSCALDQ TGLHEMKYAPNFTGGHMVMGDSFNTSLFKQTFQRVFSKDARNEFKMAFGGTLEVKCSREL KVQGCIGPCVSTNMGPCVADTEMGMGSTCQWKMCGLYPNTTFAFYFEVVNQHNAPIPQGG RGYVQFVTHYQHSSGQKRVRVTTVARNWVDASINTQHIVAGFDQEAAAV----------- -------------------------HKDDPNSFRFTEQFSLYPQFMFHLRRSQFLQVFNN SPDETSFYRHMLSREDLTQCL--------------------------------------- ------------------------------------------------------------ ------------HECSYCDAGGHVLTDDVSLQVFMEHLKKLAVSTSS------------I GDLEIEMMADMYNRMVNACQKKCVPPKYNEGDLSKGESVCLDRCVAKYMDVHDRIGKKLT AMSVQDEETVKKLQSAQQPAVIHKVIMVGSGGVGKSALTLQYMYDEFVEDYEPTKADSYR KKVVLDGEEVQIDILDDYAAIRDNYFRSGEGFLCVFSITEQESFQATAEFREQILRVKND ENIPFLLVGNKADLEDRRAVTIEEAQTRAQQWNVPYVETSAKTRANVDKVFFDLMRLIRT KKSSEKRRKKKCVILKLYTGLRDVVTEHLTKKVREDVLQALNNNFLQTLNNAWNDHQTSM VMIRDILMYMDRVYVQQNNVDNVYNLGLIIFRDWVVRFPTIREHLRQTLLEMVAKERRGE VVDRGAVKNACQMLMILGIDARSVYEEDFERPFLEQSAEFYKRESQKFLEDNSASVYIKK VEARINEEAERATHYLDKSTEEPIVKVLEEELISKHMKTIVEMENSGVVHMLKNNKTEDL ACMYKLFIRVQNGLKTMSDCVSGYLKEQGKALVTEEEGGKNAITFVQSLLDLKDRFDHFL HESFNDDKLFKQMISGDFEYFINLNQKSPEYLSLFIDDKLKKGVKGMTEQEIENVLDKSM VLFRFLQEKDVFERYYKQHLAKRLLLNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFKD MTVSNTTMEEFKAHIQQGTNLHGVDLFVRVLTTGFWPTQSATPKCNIPQAPRSAFEAFRR FYLAKHSGRQLTLQPQLGSADLNATFYGAKKEEGESKGGPRKHIIQVSTYQMVILMLFNS RDKLTYEEVKNETDIPERDLMRAIQSLALGKLTQRILSKEPKTKEIESDHVFTVNDHFTS KLYRVKIQTVAAKGESEPERKETRSKVDEDRKHEIEAAIVRIMKARKRMQHNVLVAEVTE QLKARFLPSPVIIKKRIESLIEREYLARTPEDRKIYTYVADRINIFPSRMAQTLMKARLK GAQKGHSLLKKKADALTLKFRQILKKIIETKQLMGNVMKEASFSLAEAKFTTGDFNHLVI QNVNKAQVKVRSKKDNVAGVMLPIFEPYADGSDSYELTGLSRGGQQIDKLKKNYAKAVEL LVVLASLQTSFVTLDEVIKITNRRVNAIEYVIIPKIERTLAYIITELDEREREEFYRLKK IQRKKKELNPANLLEDKDEDLLFPLRVLVTGAAGQIGYALLYNIAKGDMFGPKQPISLVL LDIESMVTVMEGVVAELQDCALPLLRETIATADVNVAFKDVDAAILVGAMPRRQGMERKD LLKANIKIFKAQGKALNQHAKKTVKVLVVGNPANTNCFICKKYAPDIPPENFSCLTRLDQ NRAQAQIAARQAVRNTIIWGNHSSTQYPDVRHASVVMEAVKDDNWINNEFIKIVQTRGGE IIRLRKLSSAMSAAKAVCDHMHDWTSGCAADEWVSMGVCSDGYDIQKGLIYSFPVNIDGT YTIVQGLKIDEFSREKMSATEAELIEEKDAALGECSGNSGVLMVGPNFRVGKKIGCGNFG ELRLGKNLYNNEHVAIKLEPMKSRAPQLHLEYRFYKQLGQAEGIPQVYYFGPCGKYNALV LELLGPSLEDLFDLCDRKFSLKTVLMIAIQLISRMEYVHSKHLIYRDVKPENFLIGRQSN KKQHIIHIIDFGLAKEYIDPETHKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEAL GHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEELATYLRYVRRLD FFETPDYDYLRKLFHDLMEKKGWECDWEFDWTGRQLRHGGSVQVVSSTNGELAATAGHSN TPITAQAEVEVVDETKCCMTTIRPFTCNDMFKFNNVNLDPLTETYGLPFYMQYLAHWPEY FQVAEAPSGEIMGYIMGKAEGHTENWHGHVTALTVAPEYRRLGLAAKLMNILEEVSEKKR CFFVDLFVRVSNKVATDMYTRLGYSVYRRVLEYYSGDTDE-------------------- ----------ERQLDCALDLMRRLPPQQIDKNLSDLIDLVPSLCEDLLSSVDQPLKIARD KSLGKDYLLCDYNRDGDSYRSPWSNTYEPHLEDGAMPSDRLRRLEIDANEAFDQYREMYF EGGVSSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRSAHYKLTST AMLWLQTTKQGSGTMNLGGSLTRQVETDANVSDASPHIANIGRLVEDMENKIRNTLNEIY FGKTKDIVNGLRSTKSLKRDALRVDLAQALQKRQT------------DEVETGEQVEILP VSDKVEPSKRITTNYMTKYERARVLGTRALQIAMCAPVMVELEGETDPLQIAMKELKAKK IPIIIRRYLPDGSYEDWGIDELIIT-RNPTLKETVTAPAGETAFTLGRGLVAGASVLGIG ALCYYGMGMSNELGAVDRATLWPPVVKDRIRDTYMYFGGGLGITAISRNHRLMNLMMRNS WMAILGTFALMIGSGMVARSIPYREGTKQLAWMAHAGIIGAVIAPLTLMGGPLLIRAAWY TAGVVGGLSTVA------------------------------------------------ ------------------------------------------------------------ ----MEIVYVYTKKRSEFGRQCNFSDRPAELHVDIAPDQTLTENFIERNPVDTGIQCVQE MSEHEVNTERFETDSRGINHTEGGWPKDVNPQEVEQVIRYRKKVEKDEMYMSTIIQLAGV MEHCIKQNNAIDIYEEYFADVDADETDEPPSAKTINVFRDPNELKRTSTHISWFPDGPRK LAIAYCNLEFQGSSPDTMDSYIWDVENPNKPEMTLKPVSPLVCLEYNPKDSHVLLGGQYN GQIAYWDTRKGSQPVEMTPIEHSHRDPAYKTVWLQSKTGTECFSASSDGQVLWWDTRKLG EPTEKLYLDPTKKQDFTKSQGAMSLEYEPTMPTKFMVGTEQGSIMSCNRKAKTPAEKIVA LYPGHHGPVYALQRNPFFPKNFLSVGDWTARIWSEDIRESSVMWTKYHMAYLTDGCWSPV RPAVFFTTKMDGTLDIWDFIFKQKDPILSLQVCDEPLHSIRVQEQARLIATGSETGTTTL LELSDGLCTLQRNEKALVTAMFERETRREKILESRHREMKLKERTKSSYEELVQRISPIA NPLAPRKLTKKLYKAIKRALRKGVREVQKFVRKGETGIVVFAGDTSPVDVICHMPLVCEE KELAYCYTPSKEDLGAACGSKRPTCMVMIKSHEEYKDLYDECYGDVKSLPLPI------- -----------------LLKTMKEANDKKLKNDLMEAIKKDNMAPFYEETCQELNWTLDE ALLKTMKEANDAELKKLDEAVDDAEKNLGETEVRDFMIKKAEYLSRIGDKEGTVSQFRKT GEKTVTVGYRLDMVFHQIRLGLFYMDHDLITRNIEKAQSLIDEGGDWDRRNRLKVYRGAY CMAIREFKNAANYFLDTVATFTSYELMDYKAFVTYTVLCSMIALNRPDLREKVVRGSEVL EVLHSLPDVRQYLFSLYNCHYGDFFKSLAKMEDMLKYDRILSPHYRFYVREMRIHAYAQL LESYSSLTLQYMAKAFGTTIDFIDQELSRFIAAGRLHCKIDKVGGIVETNRPDSKNYQYQ ATIKQGDILLNRIQKLSRVINI-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -GGLLLMGGGYYPTNTIQGLAAAAAFISSINIFGGFVITHRMLDMFKRPTDPPEYPYLYG IPAAAFLGGYGWCSQGTYLDIHQMTYLAAALCCVGALTGLSSQTTSRIGNILGMIGVSSG LAATVGLLKPPPEVLTQMAVAMGTGGLIGAIAAKRLEVTDLPQMVALFHSLVGAAAVVTC IANYMAEHAHFATDPAAGVIKTALFLGTYIGGVTFTGSLVAFGKLQGVLSSEPLMLPGRH VLNASLLAGNVGAMGYYMMSDASAGLGMLGTTTALSAIMGVTLTAAIGGADMPVVITVLN SYSGWALCAEGFMLNNNLMTIVGALIGSSGAILSYIMCKAMNRSLPNVILGGYGIST--- -SKRKIEGTHTEVNSDQTIDMIAESRDIMIVPGYGLCAAKAQYPIAEMVELLRKKGKKVR FGIHPVAGRMPGQLNVLLAEAGVPYDIVHEMDEINDDMPDVDLTLVIGANDTVNSAAEDD PESIIAGMPVIRVWLSKQVVVMKRSLGVGYAAVDNPIFFNPNTAMLLGDAKKTCDGLLQR MK-------PGCPPGLEYLTQIDQLLVHQQVELLEAFTGWETKNKYQVKNSMGQQVYFAA EESDMCMRQCCGPQRGFTIHITDNMGQEVIRVNRPFKCCAGVSCCAGCAMEVEVEAPVGN VIGHVKQQCLAPKYMIMDAILSIEGPVCICQGPCCTWDQEFVVRTGEVGKISKQWSGLVK EYFTDADNFGVSFPMDLDVKMKAVMVGAVFLIDFMFFETQQQ--DKELQEFLMMEQQKAQ FQAQIHQLTDTCWEKCIDKPRDKLDYKAETCITNCVERFIDTTVTITGRFQQLLQRSMVN RTEGLVQRRNVSSAEQDHDSKETRLTLMEEVLLLGLKDREGYTSFWNDCISSGLRGCILI ELGLRGRVELEKTGMRRRSLLNRKLLCKSDAPTGDVLLDEALKHIKESDPPQTVQSWIEY LSGETWNPLKLKYQLRNVRERLAKNLVEKGVCTTEKQNFLLFDMTTHPLTDNVIKQRLVK RVQDAVLSRWVNDANRMDKRLLSLIFLAHSSDVLENAFAPLSDEDYEVAMKRVRDLLDLD YEQMSMKDGSCDVMWCVITA---------------------------------------- ---------------------TAILGEMSKPVSWGMPGDKVCMKLWRKDNQICDLRYEKK LDLAKINLKKLKVRELKNLLSSWDEQCKGCTEKSEYVRLVEELMPKYDPEAAADDILKGF KLNWMNLRDADSGKILWQSSDDLSDPCKEHEARVPKKILKCRAVSREINFSSKEQMERFR LEQKVLFKGKCLEEWYFEFGFVIPDSTNTWQSIIEAAHESQMMPANVLNGNVVIETKFFD GDMQVSTSKVRVFYVMPKVVSRSVVCTDTKDQEEYQGEKPLYVYYCLCGQMSLILDCPVE KLPMRRRDNARVIDSNKHAHKITSEPDETIFLKRPEGIERQFRQKCKRCGLFLYYRHRNQ ITFIVDGALTKAVEMKTNVYSQISEPKKVMVTKHTKNMGKFSSVTVSTVDEEEEELEAKE IADSYAANAKVIEKQLLRKGLSKRKLLEQAEEEAKKMRPKGTLID--------------- -YADMAFTFASPGDVKVKQVDVPSFSGSFGILPDHVPLLAVLQPGVVTVLEEDGSQNKYF VSSGSVTINEDSSVQILAEEAARLDQLDGQAVREGAAKAAQELTSEEAKAEAQIAVDCYE ALSKAVECKYFITELANRLAKSAKSKEKIEMGYNFQQRKKFDYVTSELRLTEALMDPHIC ENILKYNVHAERGGSNRYAQGQSQTMGVLHGLVNKGVKVELGIPYELWDKPSAEITKMHR ACFKLAEDYEEDIEEWYYNYQYELKEYICRERYLKGKNS-FAPTDVTSEADVKDALVAQS KYGKLDVAVNCAGIGIAVQTYNFNKDRAHPLDEFQKVLTVNTGGTFNVIRLSCALMGKNE PNADGQRGVIINTASVAAFEGQRGQAAYSASKGAIVGMTLPIARDLARQGIRVNTIAPGL FDTPLLASLPEKVRTYLASTVPFPAKLGLPDEYAHLAQSIVENPMLNGEVIRLDGALRSR DFHFKISGRNAESKDGISRNYPVVDHTYDAVVVGAGGAGLRAAFGLAKEGFKTACITKLF PTRSHTVAAQGGINAALSNMEEDDWKFHFYDTVKGSDWLGDQDAIQYMTEEAPQAVIELE NYGMPFSRLENGKIYQRAFGGQTLKFGKGGQAHRCCAVADRTGHSMLHTLYGRSLYYDTN YFVEYFALDLIMEEGECRGVTAICLEDGSIHRFRAKNTVLATGGYGRTYFSCTSAHTCTG DGTAMTARAGLANQDMEFVQFHPTGIYGAGCLITEGSRGEGGYLINGEGERFMERYAPNA KDLASRDVVSRAMTIEIREGRGVGPDKDHIYLQLSHLPPEQLKTRLPGISETALIFAGVD VTRDPIPVLPTVHYNMGGVPTNYKGQVIQHDGKDHIIPGLYACGEAGCASVHGANRLGAN SLLDLVIFGRACALTIAEENKPGDAIGEIKPNAGEESVANIDNLLHSEGEAPTAELRLRM QKASQENAAVFRDGPSLQEGCVKLDGIYQDMDVKVTDKGRVWNTDLIETLELQNLMINAV QTVHSAEARKESRGAHAREDFKTRIDEYDYSKPLEGQKRN--DNHWRVHTMSFTDHNTGK TTLKYRPVIDSTLDSSKVQTIAPLIRSYMTALSQDEIISNTKTVVQGLDTLKNEHHQILN SLLTSMKTIKKGDTNLVEEKTNILKKSLEMIDLGLGEAQVMMALANHLQHVEAEKQKLRA QVRRLCQENAWLRDELANTQQKLQQSEQKGATLEEEKKHLEFMNEMKKYDSEDALGFPGD DDDENQSAMAQAASGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHD HPDVATMLNILALVYRDQGKYKEAANLLNDALGIREKTLGPDHPAVAATLNNLAVLYGKR GKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEQYYQRALEIYE TKLGPDDPNVAKTKNNLASAYLKQGKYKQKIAGRYDAGAEAEVLGWIRALTQPGMREVEK QLRNGQTLCKLAKAIKAGRMKLKFNTLSAPFKQMENIEIFLNFCQEYGVPKINQFQTVDL FEGRNMAQVLSCIQTLGSECQRHNFNGPTIGAKPTEKHVVQFTEEQLRAGHLQAGTNKCA SQSMGAARHVADIRADDMSAEGQAVLGGQMGNKGASQKGMAMGAARHVADIRADDMSAEG QSVLGGQMGYNKGASQAGMAIGAVRHVADIRADDMTAEGQTVLGGQMGYTGGASQKGMAM GSVRHVADIRADDMSEGSAVMGGQMGYTGGASQKGMSMGAVRHVADIRADDAEGQAISGG QMGYTGGASQKGMAMGATRHVADIRADDMSSQGVTSLQYGTNVGESQSGMSFGGRRDI-- -----------CHAWNRDRTQIAIPNNNEVHIYKVNWTRTHVLAEHVQRVNGIDWAPNSN RIVTCGADRNAYVWPTLVIVRINRAATCVRWSPQENKFAVGSGARLISVCYFEQENDWWV SKHIKKPLRSTVTSLDWHPNNVLLAAGSTDFKARVFSAYIKEVDQKPSSTAWGSKMTFGN VMGEFSSGGGWVHSVTFSASGDRLGWVGHDSSVAVANAATKTKFLPFLTCTWVTENSLVV GGHDCCPMLFTYDGSKVNFVAKLDEQKTSAMRHFQTLDRKATALKTLHQNTITQVSIHSG NKGQATKLTSTGVDGQLINWD--KDVEGYVGFANLPNQVYRKAVKKGFEFTLMVVGESGL GKSTLINSMFLTELYNAEYPGPSHRVKKTVDVETTNCMLKEGGVQLRLTVVDTPGFGDAV DNSNCWQPITDFIESKYDEFLNAESRVNRRTQPDSRVHCCLYFISPNGHGLKPLDIEFMK RLHDKVNIIPLIAKADTLTPDECREFKKTILNEIAQHKIKIYEFDDEEEQRLQKKLKDRV PFAVVGSNTVVDSGGRKVRGRVYPWGVVEVENLEHNDFIALRNMLIRTHMQDLKDVTNNV HYENFRFNKLSTVTKNPIAQMEEEKREHVQKMKKMEAEMEQVFEMKVKEKKQKLKDSEAD LQRRAEQMKKSLEQQQREHDEKKQQFDQERAAWEETQR-------RTTIFSPEGRLYQVE YAMEAIGHAGTCLGILAKDGVILAAERRNTNKLLDEVSNSEKIYRINDDMACSVAGITSD ANVLTNELRLIAQRYLLQYQEPIPCEQVVSTLCDIKQAYTQFGGKRPFGVSILYMGWDKH YGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQEYKEGELNLQSTLQLAVKVLSKTLD TNKLTSDKVEIASLTRQDGKTKVTILPSTEVEALIKVHEAEEAKAEAEKKK--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------SVIESLKDQASSCKQQE APVIDDIGKECVVALYDYTEKSPREVSMKKGDVLTLLNSSNKDWWKVEVNDRQGFVPAAY VKKIDASLSASQSNLADEFTISVRQTQIEKQYDNLLELGRQRKDKLEESCKAYQLVREAG ELAHWINDKETVALEQEVGEDLEQVEVIQRKFDDFQKDLKANEARLVELRTVAEKLTAMG QTEAAEKIKIQIEDLNQRWAALQHVTQERAQTLGSAHEVQRYHRDADETKDWIDEKDEAL NTEDIGHDLATVQRLQRKHEGLERDLAALGDKVKDLDETANRLMMTHPDQQTSIYEHQKE INERWNALTVKADTRKAKLLDSYDFQRFLSDFRDLMSWINSMLALVSSDELAKDMTGAEA LLERHHEHRMEIDARASTFQAFEMFGHQLLQNNHYASDDVRDKLKDLADAREQLEEAWIA RRAKLDQCLEAQLFNRDCEQAETWMAAREASMADSVDGGDSVESLIKKHEDFDRAINSQE EKISALNAFADQLITADHYDRDGISDKRDQVLERWRQLKEAMLENRSKLGEAQTLQQFSR DADEMEIWITEKLQMATDESYKDQANIQSKHQKHQAFEAELAANSDRLGSVVSMGQKLID GGQCAGGEDAVNARIAKLAQEWEFLTVKSTEKSEKLKTANRQRTYNAAVKDLEFWLGEVE HMLETEDYGKDLATVQNLVKKHQLLDADVKAHDDRIKDLNDQADAFIESGMWDTDTIKEK KQTINERYERVTTLATHRRSRLDEANTLHQFFRDIDDEEAWIKEKKLLVGSDDFGRDLTG VQNLRKKHKRLEAELSSHEPAIQAVQDTGEKLMAESNLLTDEIQQRLEQLNHNWEELKQM ATNRGQKLDESLSYQQFAASVEEEEAWILEKQHLLSAEDVGDTLAAVQGLLKKHDAFATD FQVHHDRCQEITKEGDKLIQEGNHNAEQIEQRCKTLQERLETLQEAANQRKARLIDNSAF LQFIWKTDVVESWIADKETQVRSDDYGRDLSSVQTLLTKQETFDAGLQAFEKEGIQTITA LKEQLVASNHAQTAAIEKRYSDVISRWMKLLADSDARKQRLLRLQEQYRQVEDLYLTFAK KASAFNSWFENAEEDLTDPVRCNSVEEIRALREAHDQFKASLSAAEADFNQLAALDKQIK SFNVGPNPYTWFTMEALEDTWKNLQKIIKERDGELQREQQRQEENDVLRKQFAQAANAFH SWLTETRSSMMEGTGTLEAQLEATKKKSADVRSQRGQLKRIEDLGALMEERLILDNRYTE HSTVGLAQQWDQLDQLGMRMQHNLEQQIQACNTSGVSEDALREFSMMFKHFDKDKSGKLD QNEFKSCLRALGYDLPMVEEGQTDPEFETILDTVDPNRDGHVSLQEYMAFMISRETENVQ SAQDVEQAFRALTTGDRPYITATELYANLTREQADYCISKMRPYEDTKGRVIPDAYDYGD FTRALFIN-------------SCPSYWYFDRHLNALVDCNSFEAKVPGTFCMKITQQSPG WGGWIKITRRCGSRSDTGVAWGCRWSYEENGVWRETCYCEDHDGCNGASR---------- --------------------------------LVQVHLRFHLLQETLYLTVDLIDRFLQD QVARSKLQLVGVTTMLLASKYEEMYAPEIADFVYITDNAYSKADIRRMECTILKKLDFNL GKPLPLHFLRRNSKAGEVDANKHTLAKYLMELTIVEYDMVNLHPSEIAAAALCLAMKILD WSETLVFYSKYTEKELLPIMQKMAKLVLRKLTAIKVKYQSSKFMKISVIPELNSQLVHDL AGRTTGRGRRQNNPSPGPENDLERVFVWDLDETIIIFHSLLTGSYAQRYGKDPPGSVSLG LRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFQTDGFHAAATNNLCL ATGVRGGVDWMRKLAFRYRRIKEIYNSYRNNVGGLLGPQKREQWLQLRSEIEGMTDSWLT LALKSLSIINSRSNCVNVLVTTTQLVPALAKVLLYGIGGVFSIENIYSATKIGKESC--- --------------GDGRDEESAAKQMNWPFWRISNHSDLAALHHALDLGYLMSALSVGG ERNTGQSVRTQNVMAACAIANIVKSSLGPVGLDKMLVDDVGDVTITNDGATILKLLEVEH PAAKVLTELAQLQDQEVGDGTTSVVIIAAELLKNADELVKCKIHPTSIIGGFRLACKEAC KYIQENLTVGVDELGRECIINAAKTSMSSKIIGPEMDFFANMVVDAAQAIKTSDGKGGNK YPIKAVNVLKAHGKSSKESMLIHGYALNCTVASQAMPKKITNAKIAFLDFSLQKAKMHLG VQVVVEDPEKLDAIRQRESDITKERIQKILATGANVILTTGGIDDLCLKYFVEAGAMGVR RCKRVDLKRIAKATGGTLIVTLANLEGEETYEAAMLGQAEEVTQERICDDELLLIKGTKA RTCASIILRGANDFMVDEMERSVHDALCVVKRVLESKTVVPGGGAVEAALSIYLENYATS LSSREQLAIAEFARSLLVIPKQLAVNAAKDSTDLVAKLRAYHNTSQTKAEHRDLKWIGLD LVEGVVRDNKKAGVFEPAISKIKSLKFATEAAITILRIDDMIKLAPEEKGGKSYQEAYHA GELXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSGGSHKDRTEK YRSILELVESLKAFIEALVNENVSLVISRQILSDFSAHLAKLPDDLARQVSHYTLEKIQP RVISFEEQVGAIRQLLANIYEREQNWREAANVLVGIPLETAQKQYSVDYKLETYLKIARL YLEDEDPVQAEAYINRASLLQAESDTEELQIYYKVCYARVLDYRRKFIEAAQRYNELSYK NIVAEEERMEALKKALICTILASAGQQRSRMLATLFKDERCQQLPTYAILEKMYLDRIIR SSDLQEFSAMLQQHQKAVTSDGSTILDRAVIEHNLLSASKLYNNITFEELGSLLEIPAAK AEKIASQMITEERMNGYIDQIDSIVHFEVREALPSWDKQIQSLCLQVNNIIEEISQASPE WMAKAADTQMAMKLTDAVVRSFRVAKVFRENTERINSIDFSPNGETLISSSDDDSIVIYD CQNGTPKRTLNSKKYGVDLIRYTHATNTAIHSSTKVDDTIRYLSLHDNKYIRYFPGHVKK VVTLCMSPIDDTFLSGSLDKTIRLWDLRSPNCQGLMHLPGRPVAAFDPEGLIFAAGINSE SLKLYDLRSFDKGPFATFKLQQDKDCDWTGLKFSPDGKLILISTNGQVIRLIDAFQGIPL QTFMGHANYKGLPLEASFSPDSQFVFSGSSDGKIHCWNTESGAKVTVLSCDHTGPVQCVQ FNPKYMMLASACTNMAFWLPQIDEEYLIVEKRGEKQNVGLIQFNRPKALNALFDPLMREL NQALALMERDDTIGCMVLTGSERAFAAGADIKEMQNQEFARVYRGDFLGHWKGLSLCKKP VIAAVNGFALGGGCEVAMMCDIIYAGEKAFFGQPEITIGTIPGAGGTQRLTKALGKSKTM EMVLTGNRISAQEAERCGLVSKVFPPDQLVDEAVKLAEKIASHSKLIVQMAKEAVDASFE MSLQEGLRFEKRFFHQTFSTNDRKEGMTAFVEKRAPNFTD >Flabelligera_affinis --DRKAVIKNADMAEDMQQDAVDCATQALEKYNIEKDIAAFIKKEFDKKYNPTWHVIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSGISTQLRQFQTSATRNDIDQAAKYIGAGAATV GAAGSGAGIGSVFGSLVIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLILFAFM SHYKE-GKAPETTIHRIRIALTSRNVKSLEKVCADLIKGAKEKNLKVKGPVRMPTKVLRI TTRKTPCGEGSKTWDRYQMHIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX X----------------------------------------------------------- ------IRELTSVVQKRFKFPEGTVELYAEKVGTRGLCAIAQAESLRYKLIGGLAVRRAC YGVLRFIMESNAKGCELVVSGKLRGQRAKSMKFVDGLMIHSGEPTRDYVDTAVRHVLLRQ GVLGIKVKIMLPWDPSGKNGPKNPLPDNVSIVDPKEETLPTQPYSEQKGVKMSKRGRGGS AGGKFRISLALPVGAVINCADNTGGKNLFVIAVHGYKGRLNRMPAAGSGDMIVATVKKGK PELRKKVIPAVVIRQRKPIRRKDGIVIYFEDNAGVIVNVKGEMKGSGITGPVAKECADLW PRIASNASSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGKPHGIKTARKLKIRRRDQKWHDKD YKKAHLGTRWKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP RDGCLNYIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKEKKERPRAXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPRV PSVFSKTYSTPRRPFEKERLDQELKLIGEYGLRNKREVWRVKLTLAKIRKAARELLTLDE KDSKRLFEGNALLRRLVRVGVLDEGKMKLDYVLGLKIEDFMERRLQTQVFKLGLAKSIHH ARVLIRQKHIRVRKQVVNIPSYMVRLDSQKHIDFSLRSSYGGGRPGRVKRKNLKKGHGGA DEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMPLAKDLLHPSLDEEKRKCKLKRLVQSPNSFFMDVKCPGCYKITTVFSHAQSVVICV GCSTVLCQPTGGKCRLTEGCSFRRKQHMVRMIVLSDALKSICNAERRGKRXVLLKPCSKV IIHFLTVMMQHGYIGEFEIIDDHIAGKIVVNLTSRLIKCGVISPRFDLKLHHLEQWTTRL LPSRQFGFLVLTTSGGIMDHEEARRKHLGGKILGFFFXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXX---------------------DIILTDYIAISEKNAKYLPHSAGRYQVKRFI KALCPIVQRLTNSLMMHGPNNGKKLLTMRIVEHAFEIIHLLTGENPLQVLVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREAAFRNIKSIAECLADELINAAK GSSNSYAIKKKDELERVAKSNRMTEQMTLRGSLKGHGDWVTQIATTPQFPDILLSSSRDQ SLILWRLTRDSSYGTPQRKLTGHGHFVSDVVMSSDGQFALSGSWDSTLRLWDLSTGETTR RFVGHTKDVLSVAFSADNRQIVSGSRDKSIKLWNTLGVCKYTIEEGHEDWVSCVRFSPNT QNPIIVSCGWDKLVKVWNLTNCKLKTNHYGHTRFLNCVTVSPDGSLCASGGKDGQAMLWD LNEGKHLYTLEAGCNINTLTFSPNRYWLCAASGPSIKIWDLEGKIVVDELRQEVIASG-- -PECTSLAWSSDGQTLFAGYTDNVIRVWQVSMAARXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX---SEGDDVPTPVVVGGGMDVNTALQEVLKNSLINDGLARGLHEC AKALDKRQAHLCILANNCDEPMYVKLVEALCAEHGINLIKVDDNKKLGEWAGLCKIDKEG KARKVVGCSCVVVKDYGKDSPALDSLQEYFKSRKXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMYSVSAKILKPGGERPDEFESTISQ ALLDLEMNSDLKASLRELFITGAKEVDAAGKKAIIIFVPVPQLRSFQKIQSRLVRELEKK FSGKHVVFVAQRRILPKPTRKTRRKNKQRRPRSRTLTSVHDAILEDLCFPSEIVGKRIRM KLDGSRLIKVHLDKTQQTNIEHKMETFAAVYKKLTGKYVVFEFPEFVL------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------CGSVSVHLTPAPRGTGIVSAPVPKKLL-MAGIDDC YTSCRGQTATLGNFAKATYAAVANTYSYLTPDLWKETVFTKSPYQEFTDYLSK------- ------------------------------------------------------------ ------------------------------------TPGTFTNQIQAAFREPRLLVVTDP RTDHQPVTEASYVNIPVIAFCNTDSPVKYVDIAIPCNNKSIFSIGLMWWMLAREVLRLRG TISRDVPWDVMVDLYFYRDPEEAEKE---------------------------------- -----------------------------------IMSSAMSKELRQKYNVRSMPITKDD EFQVVRAHFKG------------------------------------------------- -----------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------- -QSAKARGSHLRVHFKNTRETANTIRRMHLRRAVSFLKNVVDKKECXPFRRFNGGVGRCA QAKNWNHTQGRWPKKSAEFLLQLLKNAESNADFKGLDTDHLVIEHIQVNRAPQMRRRTYR AHGRINPYMSSPCHIEVILTEKEQAIVKPKKKKVSQKKPKRQKMMMRDXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXMGISRYTWHKRRKTGGRRIPIRKKRKFEMGRPAANTKLGP RRVHLVRTRGGNMKYRALRLDQGNFAWGSEAATRKTRIIDVVYNSSNNELVRTKTLVKNC IVQIDATPFRQWYEAHYAMPLGRKKGAKMTAAEEELVKKRSKKTMKKYKNRQKTAAVETA LSESFATGKLYACVSSRPGKAGRCDGYILEGRELEFYMRKLKSKKGKXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXX----------------------------------------- --------------------------------------PASDAYLVFGEAKIEDLTPQAH LAAADKFQADEEVDDAGVEAKDIELVVQQ------------------------MGRVRTK TIKKAARVIIEKYYTKLTLDFHTNKRICEEIAIIPSKKLRNKIAGFVTHLMKRIQRGPVR GISIKLQEEERERRDNYVPEVSAIEEVDPETKDMLKMMDMGNMAGPQLTQPVNTGXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX VRLPPEVNRILYIKNLPYKITAEEMYDIFGKYGAIRQIRVGNTPETRGTAFVIYEDIFDA KNACDHLSGFNVCNRYLVVLYYQPHKSFKKLDQQKKGEELDKMKAKYGLSAPEMKMSIGV PIKVLHEAEGHVITCETNAGEVYRGKLVEAEDNMNCQMSNITVTYRDGRIAQLENVYVRG SKIRFLILPDMLKNAPMFKKVGAGRGKSAILRAAARGRGRGDGRGGRGGXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXX-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------LGKHYTEEAVCERDTIKLALKALLEVVQSGSKNMEVAVMRRGEALKM LECDEIESYIQEIEKEKEEEAEKKKQK--------------------------------- ----------------------------------------------------EEERSKVD DLRGTPMSVGNLGEIIDDNHAIVSTSVGSEHYVSILSFVDKDQLEPGCSVLLNHKVHAVV GVLQDDTDPMVTXMKLEKAPQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIRPPK GVILYGVPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPS IVFIDEIDAIGTKRYESNSGGEREIQRTMLELLXPLDGFDSRGDV--------------- ------------------------------------------------------------ ----------------------------------------KRKPYSPFQGTSNVDYALAR ADDLINWARKSSLWPLTFGLACCAVEMMHFAAPRYDMDRFGVVFQASPRQADCILVAGTV TNKMAPALRKVYDQMPEPRWVISMGSCANGGGYYHYSYSVLRGCDRVIPVDIYVPGCPPT AEALLYAVLQLXKKIKKMKTVQMWYRKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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CTHPVEDGILDCGSFEKFLHERIKVHGKTNNFRNKLTVNADIPFSKRYLKYLTKKYLKQN NLRDWLRVVASTKDAYELRYFQINNEEDDDEEDNXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKKLQRQLEFLEVQEEYIKDEQKNL KKEYLHAQEEVKRIQSVPLVIGQFLEAVDQNTGIVGSTTGSNYYVRILSTIDRELLKPSA SVALHKHSNALVDVLPPEADSSITMLQSDEKPDVQYSDIGGMDIQKQEVREAVELPLTHF ELYKQIGIDPPRGVLMFGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVR DVFRL------------------------------------------------------- ------------------------------------------------------------ --------------------------------------------------XXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AAIVMLTPSKFMCVEAFSEYPPLGRFAVRDMRQTVAVGVVKSVEK KDPSAGKVTKAAQKAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMSKLSRDLLGESVSGILQKKKRFTQTVELXISLKNYDPQKDRRFAGTVKLKHIPRPK LKVCMLGDQQHCDEAKANNISSMDVEALKKLNKNKKLIKKLAKKYDCFIASDTLIKQIPR ILGPGLNKAGKFPTMITHNEPMVAKVDEVKSTIKFQMKKVLCLAVAVGHVNMTKEELSAN IMLAVNFLVSLLKKNWQNVRALYIKSTMSPSLRIYMAESDKLNIDSIIARLLEVRGSRPG KNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN IKLWKTFTDCFNCLPIAAII---------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXMTDPSIHNLRDPFAEDTQIHIRIQQRNGRKTLTTVQGISSEFDLKKI VRVAKKEFACNGTIVEHPEYGEVIQLQGDQREHICDFLKRVGLEEQIKVHGFXXXXXXXX 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YGELPESAKINEEFDDNITFDEIDDIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------ ------------------------------------------------------------ ------VRGMLPHKLHRGKEAMGRLKVFEGIPPPYDKKKRLVVPSALRTLRLKARRNFCL LGRLSHEVGWKYQHVVSTLEEKRKVRSHEFYLKKKKENKLKAQAVKIAPYQKIIEGYG-X XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX MTNTKGYRRGTRYMFSRQFRKKGVIPLSTYMKTYKRGDIVDIKGCGAVQKGMPHKSYHGK TGRVYNVTQHAVGIIVNKRVRGDILPKRINLRAEHVKHSKCKLDFLRRVKENEVKKAEGR AKVSTKRQPAQPRSGHIVRTRYNKPELLEPIPYEFIA--RAHYKQVSPPDPEMTWSAMTD RAANMAFLTEIFRGLSIVMSHLFKEPATLNYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAICPAQAITIEAETRDDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVXGPNFEY STETHEELLYNKEKLLQNGDKWEPEIAANLQADHLYRXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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LIRPDGEKKAYVRLASDYDALDVANKIGII------MKLANEKHTINVLNIGNVPKSLKP -EYKYPVGPWLVGLFIFVVCGSAIFQIIQSIIMXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX >Glycera_tridactyla MTDRKAVIKNADMSEDMQQDAVECATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSGLNSQIRQLQTSATQRDIDQAAKYIGAGAATV GVAGSGAGIGSVFGSLVIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLILFAF- -------------IHRIRITLTSRNVKSLEKVCADLIRGAKEKNFKVKGPVRMPTKILRI TTRKTPCGEGSKTWDRYQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADMDQVM QFLEPAKQFAKDSIRLVKRCTKPDRKEFQKIAVATAIGFAIMGFIGFFVKLIHIPINNII VMSAQVSKKRKFVADGVFKAELNEFFTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVL GEKGRRIRELTSVVQKRFSFPEGTVELYAEKVATRGLCAIAQAESLRYKLIGGLAVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGEPTHDYVDTAVRHVLLRQ GVLGIKVKIMLPWDPSGKIGPKHPLPDQISIVEPKEEEIPSQPKSEQKGGK--KRGRGGS AGGKFRISLALPVGAVVNCADNTGAKNLYVIAVNGIKGRLNRLPAAGTGDMIVATVKKGK PELRKKVMPAVIIRQRKPVRRKNGVFIYFEDNAGVIVNNKGEMKGSA------------- ----------RKGKVQKVSLGPQVLDGENVFGVAHIFASFNDTFVHVTDLSGKETIARVT GGMKVKADRDEASPYAAMLAAQDVAEKVKTLGITALHIKLRATGGNKTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL------------LRNHRRDQRWHDKD YKKSHLGTRWKANPFSGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP RDGCLNYIEENDEVLVSGFGRKGHAVGDIPGVRFKVVKVANVSLL------------EGI VTLRTRKFLTNRLLCRRQMVVDVLHPGRATVSKTEIREKLAAMYKSTPDVIFAFGFKTQF GGGKTTGFALIYDSLDFAKKFEPKYRQVRHGTRKQRKERKNRQKK-----------MPRI PLVCRKTYTTPRRPFEKERLDQELKLIGQYGLRNKREVWRVRFTLAKIRKAARELLTLEE KDQRRLFEGNALLRRLVRIGVLDESKMKLDYVLGLRLEDFLERRLQTQVFKLGLAKSIHH A----------------------------------------------------------- --MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIGEAREELMRMLAEDELRD AVLLVFANKQDLPNAMNAAEITDKLGLHSLRQRNWYIQATCATSGDGLYEGLDWLSNQLK NQKMPLAKDLLHPSPEEEKRKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRKKAHMVRMNVLADALKSICNAEKRGKRQVLIRPCSKV IVRFLTVMMKHGYIEEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVAIRDLEAW---- -------------------------------------MGRMHAPGKGISQSALPYRRSIP TWLKLTSEDVKEQIYKHAKKGLTPSQIGVRLRDSHGVAQVRFVTGNKILRILKKKGLAAS IPEDLYHLIKKAVAIRKHMERNRKDRDSKFRLILVESRIHRLARYYKTRKVLAPNWKY-- ----------------------------------------EKYAKYLPHSAGRYQVKRFR KAQCPIVERLASSLMMHGRNNGKKIMTGRIVKHAFEIIHLLTGENPLQILVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQSIWLLCTGAREAAFRNIKT-------------- ----------------------MTDQMTLRGTLSGHGGWVTQIATTPQYPDMILSASRDK TLIMWKLTRDTNYGIPQRALKGHGHFVSDVVMSSDGQFALSGSWDSTLRLWDLSTGTTTR QFVGHTKDVLSVAFSADNRQIVSGSRDRSINLWNTLGVCKYTIEDGHSDWVSCVRFSPNT QNPIIVSCGWDR---------------------------------------QDKQAMLWD LNEGKHLYTLEGGEVINSLCF------------------DLEGKAVVDEVRPEVFNTSAE PPQCISLAWSADG----------------------MREYKLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKVVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTFNDLHDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKLARDFNCAFLETSAKSK INVNEIFYDLVRQINKKNPERMSEEKKEGSEHINLKVIGQDGSVVHFKIKKNTPLRKLMS AYCERTGVKMEAMRFRFDGQPINETDTPSQLDMEDGDSIDVFQQQTGGMATLPMNPKPFL NGLTGKPVMAKLKWGMEYKGYLVSVDGYMNLQLANTEEYIDGALTGNLGEVLIRCNNVLY IRGVEEEEEDGEMKEMSDAEGDDVPSA-GVGGSMDISTALQEVLKLAITHDGLARGLREC AKALDKRQALLCILANNCDEPMYVRLVEALCAEHGINLMKVDDNKKLGEWAGLCKIDKEG KARKVVG---------------------------MAAIRKKLVIVGDGACGKTCLLIVFS KDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSI DSPDSLENIPEKWTPEVRHFCPNVPIILVGNKKDLRNDENTRRELAKMKQEPVKPEEGRQ MSDKINAFNYLECSAKTKEGVREVFETATRAALQVKKKKKNKMDDFQSAEENAFVVDEVS NIIKESIEGAIGGNAYQHNKVNQWTSNVVEQCLNQLTKLNKPFKYIVTCVIMQKNGAGLH TASSCFWDNTTDGSCTVRWENKTMYCIVSVFGLNIMFSESVKIVKPAGEKPDDFEQTISQ ALLELEMNSDLKAQLRELYFTGAREIDVAGKKAIIISVPVPQLRAYQKIQVRLVRELEKK FSGKHVVFIAQRRILPKPTRKTRRKNKQKRPRSRTLTAVHDAILEDLVFPAEIVGKRIRI KLDGSRLIKVHLDKNQQTNVEHKIDTFSTVYKKITGKDVNFEFPE--------------- ------GRGRGKEGEKEWIPVTKLGRLVKDMKIKSLEDIYLFSLPVKEFEIIDFFLGTAL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDYNGHVGLGVKCSKEVATAIRGAIILAKLSV IPVQR--------------------------------------------RIFDLAGIKDI YVNSFGRTKTTENMAKATIMALRKSSSIYIPSDWDKEEKVENPLSKH------MSGGLDV LGLKEEDVQKFLVCSTHLGASNVDFQMEQYVYKRKPDGTYIINLRRTWEKLLLAARAIAA IENPADVCVISARPWGQRAVLKFAAATGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDP RTDHQPVREASYVNIPVIALCNTDSPLRYVDIAIPANNKGQHSIGLMWWMLAREVLRLRG TISREVPWDVMVDLFFYRDPEEIEKE---------------------------------- ------------------------------------------------------------ ---------------------------------RDKANGASVHVGIHPSKVVILKLKMDK DRKRILERKARSRQQGKHTEESV-SPSSTNVGSTVRQRKPASSGAGAAGMWRFYTEDSPG IKVGPVPVLVISLLFIASVFMLHIWGKYTRGKRDGKKKSTINEVVTREYTINIHKRIHGV GFKRRAPRALKAIKEFAESQMGTADVRIDTRLNKHMWSKGVRNVPYRVRVRLARKRNEDE DSVHKLYTLVTYVPVTTFKGTQTVNVDSSAKSEFLVNGKYRLVRKIGSGSFGDIYLGINI SNGEEVAVKLESHKARHPQLLYESKLYKILQGGVGIPHIRWYGEKDYNVLVMDLLGPSLE DLFNFCSRRFTMKTVLMLADQMIGRIEYVHNKNFIHRDVKPDNFLMGIGRHCNKVFLIDF GLAKKYRDNRSRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRGS LPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGYPAEFAMYLNYCRGLRFEEAPDYMYLR QLFRILFRTLNHQYDYVFDWTILKQRAA--MNPEKLKARIGGKGTARRKKKVVHRTATTD DKKLQSSLKKLSVNNIPGIEEVNMIKDDGQVIHFNNPKVQASIAANTFAITGHAETKQIT EMLPGILNQLGTDSLANLKKLATATGDIDDDDDEVPDLVENFDEASKGEMTRYSLNAENP SKSAMARGSHLRVHFKNTRETAHNIKHMHLRRAVRYLKNVTDHKECVPFRKYNGGVGRCA QAKNWKATQGRWPKKSAEFLLQLLKNAESNAEYKGLDTDSLMIDHIQVNRAPQMRRRTYR AHGRINPYMSSPCHIEVILVEHEQADRK-------------------------KRELSEE QKQEICEAFELFDTDKDGAIDYHELKVAMRALGFTVKKADVLKVLKDYDNQNTGKILYHD FSEVMTDMMLDRDPQEEMMKAFQLFDDDDSGKISLRNLRRVARDLGENMADEE------- ----------------------------------------------------------GS HRVHEVRTRGGNKKFRALRLDSGNFSWGSESCTRKSRIIDVVYNATNNELVRTKTLVKNA IVMIDATPSKQWF-----------------------------------------AKVESG LEEQFSTGRLLASISSRPGQCGRCDGYIL------------------MSLVVPEKFLHIL RVMNTNIDGGRHVPFALTAIKGVGRRFASIVCKKADIDTSKRAGELSEEEVEKLITIMTN PRQYKIPDWFLNRQKDVNDGKYSQVLANQLDNKLREDLERLKKIRAHRGLRHYWGLRVRG Q------------------ASGSDSDSDEEVPDLEEVAQAAGLPEELVSKAKQSRSEKKA RKAMSKLGLKQVAGVSRVTIRKSKNILFVISRPDVYKSPASDTYIVFGEAKIEDLSQQAQ VRAADQFKTEEEVDESGVEAKDVELVMSQANVSRAKAIKALKNNGNDIVNAIMXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMRWEY KEEHPFEKRRAEGEKIRKKYPDRVPVIVEKAPKARVGDLDKKKYLVPSDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGALYQEHHDEDFFLYIAYSDESVYGMRELRIVKL CLNICVGESGDRLTRASKVLEQLTGQQPVSSKARYTVRSFGIKRNEKIAVHCTVRGAKAE EILERGLKVREYELRKNNFSATGNFGFGIQEHIDLGIKYDPGIGIYGMDFYVVLGRPGFG VPHKKHKSGVVGRSHRIGKEESMKWFQQKYD-------MGIKFLEFVKPFCAVLPEISKP ERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGIS PIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMIITVGQAIVYVMTGMYGDPHE IGAGVCLVIILQLFCAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVN TGRGTEFEGAIIALFHLLATRSDKVRALREAFYRQNLPNLMNLLATVFVFAIVIYFQGFR VDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAAKFGGNFIVNLLG VWADVGGGGP-------------------------------------------------- ------------------------------------------------------------ ----------------------------------XXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX ------------------------------------------------------------ ------------KCTSCKFRKQLPIKRCKHFELGGDKKKKGQMIMFMGRVIRCQRKGAGS VFTAHTRNRKGAAALRAVDFAERHGYIKGVVKDIIHDPGRGAPLCKVSFRDPYRYKLKTE TFIASEGMYTGQFLY--------------------------------------------- -------------------------------------GGIKDKPLLKAGVSYYLHKSRGQ QWPIVRGVAMNPVNHPHGGGNHQHIGFPSTVSKKAPFAQQVGLVGARSSGR--------- -AKRTKKVGIVGKYGTRYGASLRKMVKKIEISQHAKYTCSFCGKTKMKRRAVGIWHCGSC MKTVAGGAWTYNTTSAVTVKSAIRRLKELKD----------------------------- -------------------CIHLVSDEYEQLSSEALEAGRICANKYLVKHCGKDAFHLRM RPHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVA---------------------- ------------------------------------------------------------ ----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX X---GTSSFGKRHNKTHTLCRRCGGRCYHIQKKTCSRCGYPAQRIRKYNWSEKAKRRKTT GTGRMRHMKIVFRRFRNGFREG--------MVDDRAAAKELDQWIEQLNECKQLAENQVK TLCERAKEILTKESNVQDVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDR GYYSVETVTLLVALKVRFKDRITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDGQIFTLHGGLSPSIDTLDHIKALDRIQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHSNSLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRC GNQAAIMELDDALKYSFLQFDPAPRRGEPHVTRRTPDYFLMGAYKYMQELYRKKQCDVLR FLLRVRCWQFRQLSTIHRTSRPSRPDKARRLGYRAKQGIVIYRIRIRRGGRKRPVPKGAT YGKPTNQGVNSLKNQRSLQAVAEERVGRKCRSLRVMNSYWVGQDSTYKYFEIICVDPFHK AIRRDAKINWICRPTMKHREMRGLTSANRKSRGLGKGHNFHKTIGGSR------------ ----GIAIGRLMEERKAWRKDHPFGFVARPTKNPDGTLNLMNWECAIPGKKNTPWEGGLY KLRMLFKDDYPSSPPKCKYEPPLFHPNVYPSGTVCLSLLDEEKDWRPAVTIKQILLGIQE LLNEPNVRDPAQAEAYTIYCQNKVEYERRVREQAMRFRDPSLGKSSKMLQHVNYRMRCTL QDGRIFIGTFKAFDKHMNLILGDCDEFRKIKAKKTREREEKRVLGLVLLRGENLVSMTVE GPPPAEEGMARVPLPGGSGGPGMGRAAGRGIQSGPGLQGPVRGVGGPSQSMMQPQPGMGR GGPPENVPTFKLVLVGDGGVGKTTFVKRHLTGEFEKKYVATLGVEVHPLSFHTNRGVIRF NVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRITYKNVPNWHRDLVRVCENIPIVLCG NKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLVGDPNLEFVAMPA LAPPEVHMDPTLAKQYEEELEIAQKVALPDDDDDLTEGIKGYYISKIEELQLVNSEKTQN LRRLEAQRNELNAKVRMLREELQLLQEQGSYVGEVVKAMDKKKVLVKVHPEGKFVVDLDK NIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEI KEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ KFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRLESGSGGDSEVQRTMLELLNQLD GFEPKQNIKVIMATNRIDILDSALLRPGRIDRKIEFPAPNEEARLDILKIHSRKMNLTRG INLRKIAEMMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFELSVAKVMQKDSEKNMSI KKQWKLGFAENFALSGAAAIISKTAAAPIERVKLLVQNQDEMIKAGRLDKPYKGVIDCTA RTFRTEGIIPFWRGNLANCIRYFPTQALNFAFKDQIKAMFKLQKSDSYSVKFSKNIASGG AAGAMSLCFVYSLDYARTRLANDAKSSKKRQFNGLIDVYKKTLKSDGFVGLYRGFVISCV GIIVYRGCYFGFYDTLKPIVLGEDAGLFVSFALGYVVTITSGLISYPIDTIRRRMMMTSG EAVKYKGSMDCAVQVVRNEGFMSLMKGAGANILRGVAGAGVLSGFDKFKEIYISWRLMAD QSDLDRQIEQLRRCEVIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLK ELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQV YGFYDECLRKYGSITVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRAIDRK QEVPHDGPMCDLLWSDPEDTQGWGVSPRGAGYLFGSDVVATFNTDNNVDLICRAHQLVME GYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEAVQRDFTIFEAAPQESRGKPQADYFL VRLPPEVNRILYIRNLPYKITGDEMYDIFGKYGAIRQIRVGNTPETRGTAFVVYEDIFDA KSACDHLSGFNVCNRYLVVLYYQSNKAFKKVDTEKKQQEIDKMKAKYGLSTPE--MSIGV PIKVLHEAEGHVVTCETKTGEVYRGKLLEAEDNMNCQMSNITVTYRDGRVAQLEHVYIRG SKIRFLILPDMLKNAPMFKKVGAGRGKSAILRAAARGRGRGGGGRGG--MQNEGGEYVDM YIPRKCSASNALIHAQDHASIQINLAEVDDKTGRMTGQYKTYAICGAIRRMGESDDSLRR LAQQDSIIAKMARGPKKHLKRLNAPKHWMLDKLGGNFAPRPSTGPHKMRECLPLMVFLRN RLKYALTYMECKQILNQRLIKIDGKVRTDNTYPAGFMDVVTIEKTAENFRLIYDVKGRFA IHRISPEEAKYKLCKVRKVGTAAKNVPYLVTHDARTIRYPDPLVKVNDTIKLMSTKDDEY DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKVIKAQIWDTA GQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADNNIVIMLVGNKSDL RHLRAVPTDEAKGFAEKNTLSFIETSALDSTNVETAFQNILT------------------ ----------------------MSSRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVR GKDIVVLGIEKKAVAKLQEDRTVRKIALLDDHVAMAFAGLTADARILINRARIECQSHRL TVEDPVTLEYITRYIAQLKQRYTQSNGRRPFGLSTLLVGFDGTPHLYQTDPSGTYHEWKA NAIGRSAKTVREFLEKHYTDDVASENESIKLALKALLEVVQSGSKNMEVAVMRRDQALQT LESEEIDKYIAEIEKEKEEEAEKKKQKGGGQGGDKKDDKDKKKKYEPPVPTRVGKR-KKM KGPDIANKLPQVTPHTRCRLKLLKSERIKDYLLMEEEFIKNQERLKPQEEKQQEERSKVD DLRGTPMSVGSLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDQLEPGCSVLLNHKVHAVV GVLGDDTDPMVTVMKLDKAPQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIRPPK GVILYGAPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPS IVFIDEIDAIGTKRYESNSGGEREIQRTLLELLNQLDGFDSRGDVKVIMATNRIETLDPA LIRPGRIDRKIEFPLPDEKTKRRIFNIHTNRMTLADDVNIDDYVMAKDDLSGADIKAICT ESGLLALRERRMKVKNEDFKKAKENVLFRKNEGTPEGLYLKRKPYSPFR-DNKVDYAVAR VDDLVNWARKSSLWPLTFGLACCAVEMMHFAAPRYDMDRFGVVFRASPRQADCIIVAGTL TNKMAPALRKVYDQMPEPRWVISMGSCANGGGYYHYSYSVVRGCDRIIPVDIYVPGCPPS AEALLYGVLQLQKKIKKMKTVQMWFRKTEFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYA NNSNYKNDTMIRKEAYVHKAVMEELKRIIQDSEIMQEDDSLWPAPDRVGRQELEIVIGDE HISFTTSKIGSLVDVNQSKDPEGLRTFYYLVQDLKCLVFSLIGLHFKIKPI--------- ----------------------------------------------RKSEIEYYAMLAKT GVHHYNGNNIELGTACGKYFR---------------------MTEYKLVVVGAGGVGKSA LTIQLIQNHFVEEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGF LCVFAVNNTKSFEDINQYREQIKRVKDADEVPMVLVGNKVDLPTRAVETKQGRALGDSFG IPYIETSAKTRQGVDDAFYTLVREIRKYMTDRYNIHSQLEHLQSKYIGTGHADTTKWEWL TNQHRDSYASYMGHFDMLNYFSLVENEAKARVRFNLMERMVQPCGPPPERPEDMKVELCA FSGFKIYPGHGKKIVKTDGRAYTFINAKCAKSHLMKRNPRKVNWTVLYRRKHKKG----- ------------------------------------------------------------ ---MKLNISYPATGCQKLLEVDDDLKLRAFYEKRISAEVSCDTLGDEWKGYVVRISGGND KQGFPMKQGVLSTQRVRLLLAKNHSCYRPRRSGERKRKSVRGCIVDANLSVINMVIVRKG EQEIPGLTDTTVPRRLGPKRASKLRRLFNLSKEDDVRQYVVRRPLP-------------- ------------------------------------------------------------ ------------------------------------------------------------ -----PLDLRKKKTRAIRRNLTRHEASIKTAKQQHKE--------------KGPKVTDKV FFDIEIGGEAAGRIVIGLFGKTVPKTAENFKTLAEGTQGYKGSKFHRVIKDFMIQGGDFT RGDGTGGKSIWFKDENFKLTHYGAGWLSMANAGKNTNGSQFFITTKKTPWLDGKHVVFGK ILEGMDIVRKIENSKTDRDKPEKEVVIAESGSLPVETPFAVSKEDA--KKKKLVLKFTVD CTLPVEDGIMDCTSFEKFLNERVKVNGKTNNFKNKVVVNSDIPFSKRYLKYLTKKYLKKN NLRDWLRV--------------------------IKDDKAEEEKTVGGCEGPDAMYVKLV SSDGHEFIVKREHALTSGTIKAMLSGPGQFAENETNEINFREIPSHVLQKVCMYFTYKVR YTNSSTEIPEFPISPEIALELLMAANFLDC-----------HKTAKSCWFAIHDKVYDVT KFLEEHPGGEEVLLEQAGSHATEAFEDVGHSTDAREMMDPYLLGELPEHERSSWTSWLLP LGIAIVAALVYRMVMSYMLQHLHNGWQVDQAILSEEDRVVVIRFGHDWDPTCMVMDETLY RVAEKVKNFAIIYLVDITKVPDFNKMYELYDPCTVMFFYRNKHIMIDLGTGNNNKINWAM EDEQEFTDIVETVFRGARKGRGLVVSPKDYSTKYRYKRLQRQLEFLEVQEEYIKDEQRNL KKEYLHAQEEVKRIQSVPLVIGQFLEAVDQNTGIVLSTTGSNYYVRILSTIDRELLKPSA SVALHKHSNALVDVLPPEADSSITMLGADEKPDVTYSDIGGMDIQKQEVREAVELPLTHF ELYKQIGIDPPRGVLLFGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVR DVFRLAKENSPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTVNVKVI MATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFGTITARMNLSDEVDLEDYVARPD KISGADINAICQEAGMQAVRENRYVVLAKDFEKGYKNNIKKDETEHEFYKAHQPLTIQVI RDRVILVLKLYDKVDAEKLTLESH---------------------EFGFEIPDADAERLL RPADVVQYIADKEDV--------------------------------LREDLLRGIYAYG FEKPSAIQQRAIKPIVKGRDVIAQAQSGTGKTATFSIAILQCLDTQVRETQALVLSPTRE LAVQIQKVLLALGDYMSVQCHACIGGTNVGEDIRKLDYGQHVVSGTPGRVFDMIRRRNLR TRAIKMLILDEADEMLNKGFKEQIYDVYRYLPPATQVCLISATLPHEILEMTSKFMTDPI RILVKRDELTLEGIKQFFVAVEKEEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKM REANFTVSSMHGDMPQKEREAIMKEFRSGASRVLITTDVWARGLDVQQVSLVINYDLPNN RELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI------ ----------------------GCKVPQDVLLRLLEGLQNGRESEQSHFQYVAQVPRIGI GMDSCVTPLRHGGLSLVQTTDFFYPLVDDPYMMGKIACANVLSDLYALGVTECDNMLMLL GVASKMTDKERDVVVPLMMRGFKDQAEEAGTSVNGGQTVLNPWMTIGGVATTVCQSNEFI MPDNAVVGDVLVLTKPLGTQVAVNAYQWLDQSERWNRIKLVVSEDDVRKAYQRAMFSMAR LNRTAARLMHKYNAHGATDVTGFGLLGHANNLAKVQKNEVGFVIHNLPVIAKMAAVSKAC GNMFGLLQGNSAETSG-------------------------------------------- ------------ALVMVLVSVNAYFINIDAHAEECFFDKVSTGTKMSLMFEVAEGGFLDI DVKIIGPDGKSIYSGERESNGKYTFAAHMDGIYKYCFGNKMSTMTPKIVMFSMDIGEKPK AHQNKLEEMINELSTSLTGVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMT LGQIYYLKRFFEVRRVV------------------------------------------- --------------KERVLIEGSVNALRISIAVKQADELEKILCHKFMRFMMMRAENFRV LRRKPTEGYDISFLITNFHTEQMYKHKLVDFIIQFMEEIDKEISEMKLAVNSRARISAEE FLKRFSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLV TMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTMPNTFKTLDSWRDEFLIQASPRDPEN FPFVVIGNKIDLENRAVPTKRAQSWCHSKGDIPYFETSAKEAINVEQAFQTVAKNALAQE TNVELYNEFPDQIKLTNDQNREGCGCTAPFDARFPNQNQTRNCWQNFVDFHRCHKIEDYQ PCDYFKGVYESLCPAEWVERWNEQLDNGSFAGKI-------------------------- ---------------------------------------------------WDLAADKNT LQSEQPLQVARCTKIINADSEDPKYIINVKQFAKFVVDLGDQVAPTDIEEGMRVGVDRNK YQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPEKFVNLGI EPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMART KKACIIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDT LDPALMRPGRLDRKVEFGLPDLEGRAHIFKIHARSMSVEKDIRYELLARLCPNSTGAEIR SVCTEAGMFAIRSRRKMATEKDFLEAVNKVIKAYAKFSATPRYMTYN------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------SGNTLPSALDNILPPTRPTDKPLRLPLQDVYKIGGIGTVP VGRVETGIIKPGMIVSFAPAGLSTEVKSVEMHHESLTEALPGDNVGFNIKNVSVKDIKRG NVAGDSKNDPPKEAKNFTAQVIILNHPGQIRAGYAPVLDCHTAHISCKFLKLEEKCDRRT GKKLEDAPQHVKSGDSAVVILEPSKP---------------------------------- ---------------ELEQLRQEAEQLKNQIREARKAAADTTLSQAAANVEPVGRIQMRT RRTLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDGFTTNKVHAIPLRSSWVMTCAYAP SGNYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDNQIVTSSGDMTCA LWDIETGQQTTSFQGHTGDVMSLSLAPDYKTFVSGACDASAKLWDIRDGMCRQTFSGHES DINAITYFPNGYAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLG GYDDFNCNVWDTLKQDRAGVLAGHDNRVSCLGVAENGMAVATGSWDSFLRIWNMSYAYLF KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES FRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSNSNMVIMLIGNKSDLEARR DVKKEEGEAFAREHGLIFMETSAKTAANVEEAFINTAKEIYQKIQDGVFDINNEANGIKI GPQHSPTSPSGGGGAKPGGGMTRGRIELGDVTVHNINQLKRLNQVVFPVTYNDKFYKDVL DVGDLAKLAYFNDIVVGAVCCREDKSAGSRRLYIMTLGALAPYRRLGIGTVMLEHVLSIC EKDANFDNVFLHVQVNNESAIKFYEKFGFEIVERKQNYYKRIEPADAFVLQKTFRKMPKQ IMEIKDFLLTARRKDAKSVKIKRNVKFKVRCSRYLYTLVVPDKEKAEKLKQSLPPGLAVK ELKMSKLSRDVLTEAIAEVLTKKRKFTETVELQISLKNYDPQKDKRFAGTIKLRHVPRPK MSVCVLGDQQHMDEATANKISCMDVDALKKLNKNKKLVKKLAKKYDAFLASDSLIKMIPR ILGPGLNKAGKFPTAITHQDSMVAKLEEVRATIKFQMKKVLCLAVAIGHVNMSEDELLGN ITLAINFLVSLLKKNWQNVRALYI-----------MADADKLNIDSIIARLLEVRGSRPG KNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDVHGQYYDLLRLFEYGGFPPES NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLNAGRPVTPPRGTAKGK GKM--------------------------------------------------------- ------DPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPF ICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDEL PAEFKLYLPIQKKMTESMIQNFQDPFAEDNEIHIRIQQRNGRKTLTTVQGISPDYDLKKI VKACKKEFACNGTVVEHPEYGEVIQLQGDQRTKISDFLCKVGLQGSIKVHGFSALFNFQS LLTVVLLLICTCAYIRSIAPRMLDKNKEGLLGIFWKCARIGERKSPYVAVCCIAMAFSIL F--SSRVCSGLARQLPNTLRQRKSLGAGFVASRNVSTSAEVSSILEERILGTVSANLDET GRVLSIGDGIARVYGLKNIQAEEMVEFSSGLKGMALNLEPDNVGIVVFGNDKLIKEGDIV KRTGAIVDVPVGEGLLGRVVDALGTAIDGKGDLGAKSRARVGTKAPGIIPRISVREPMQT GIKAVDSLVPIGRGQRELIIGDRQTGKTAVAIDTIINQKRFNDGTDEKKKLYCIYVAIGQ KRSTVAQIVKRLTDADAMRYTIVVSATASDAAPLQYLAPYSGCAMGEFFRDNGKHALIIY DDLSKQ-XAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDNFGGGSLTALPIIE TQAGDVSAYIPTNVISITDGQIFLETELFFKGIRPAINVGLSVSRVGSAAQIKAMKQVAG SMKLELAQYREVAAFAQFGSDLDAATQQLLNRGVRLTELLKQGQYVPMAVEEQVAVIYAG VRGHLDKVDPSRITDFEHKFLQHIRASHTDLLGQIRADGQISPENDAKLKDIVTTFLAGF MEALYSIPFTVLEVPNLKIKKPSWVKKPSSMFIFACVLMSYFLVTGGIIYDVIIEPPSIG STTDEKGNSKPVAFMPYRVNGQYIMEGLASSFLFMIGGLGFIILDQTNKPNTPRLNRILL FCIAFVCIVISFGMCRVFMRMKLPMPKVKRSKKPPPDGWELIEPTLDELDQKLREAETEP HEGKRKVEALWPIFKLHHQKSRYIYDLFYRRKAISRELYEYCLKENIADRNLIAKWKKEG YENLCCLRCIQARDTNFGTNCICRVPKSKLEEGKIVECVHCGCRGCSGEYAQVTKMLGNG RLEAMCFDGMKRLCHIRGKLRKKVWINTSDIILIGLRDYQDAKADVILKYTPDEARNLKT YGELPESVNISDDNDDNITFDGVDD-LVRFLMKLSHETVTIELKNGTQVHGTIVGVDVCM NTHLKAVKMTLKNRDPVQIDTLSIRGNNIRYFILPDSLPLDTLLIDDTPKARAKK--LQK PKSEMSPEELAQREQEEFNTGPLSVLTQSVKNNTQVLINCRNNKKLLGRVKAFDRHCNMV LENVKEMWTEVPRTGKGKKKSKPVNKDRYISKMFLRGDSVILVLRNPLPLIIDARGHLLG RLASIVAKTILNGQRVVILRCEGINISGSFYRNKLKYLAFLRKRMNTNPSKGPYHFRAPS KVFWRVVRGMLPHKLHRGKEALGRLKVYEGIPAPYDKQKRLVVPSCLKVLRLKQRRRFCD LGRLSHEVGWKYQGVVASLEERRKVKSS-------------------------------A GDATKGKKVFVQRCAQCHTVEKGGKHKTGPNLNGLMGRKTGQAAGFSYTDANKNKGITWG KDTLWVYLENPKKYIPGTKMVFAGLKKKNERADLISYLEESTK----------------- ------------------------------------------------------------ ----------------ARQTHPDSLRALYGTDDQKNGLHGSDSFTSAAREVRFFFPDSVV EPIAVGQAAHDYLSKSVNPTLLKGLTELCKQK-----------------------MFEAR LVQGTLLKKVLEAIKDLLNEATWDCSSTGMSLQSMDSSHVSLVSLLMRSDGFDTYRCDRN LSMGIKLGSMSKILKCASNEDAITIKAGDDADTVTFMFESPNGEKVSDYEMKLMDLDTEH LGIPETDYSAVIKMPSGEFQRICRDLSQIGESIVICCTKEGVKFSASGDLGTGNVKLAQT ANVDKEEEAVIIEMQEPCTLTFALQYLNFFTKATPLSNRVTLSMSPDVPLVVEYKIGEMG YVRYYLAPKIEDGDDAKSLAAYHTTQQAAKGRVVAVIGAVVDVQFDDELPPMLNALEVTG RSPRLVLEVAQHLGENTVRTIAMDGTEGLVRGNECVDTGLPISIPVGPGTLGRIMNVIGE PIDERGPIPAASTAAIHAEAPEFVDMAVEQEILETGIKVVDLLAPYAKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVINLKDDSSKVSLVYG QMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGCMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIA ELGIYPAVDPLDSISRILDPNIVGENHYNIARGVQKILQDYKSLQDIIAILGMDDLSEED KLTVSRARKIQRFLSQPFQVAEVFTGSAGKLVPLKDTIKGFQMILEGEMDHLPEIAFYMV GPIEEVVSKAERLAEDK----------------------AKKDFHAAKHPELPIPNLHVI KALQSLKSRGYVTEAFSWRHYYWYLTNEGIQYLRDFLHLPPEIVPSTLKRQ--------- -----------------MGKQNSKLKPEVLADLRENTEFSEVEIQEWYKGFLKDCPSGHL SVEEFKKIYGNFFPYGDASKFAEHVFRTFDTNGDGTIDFREFICALSVTSRGKLEQKLKW AFSMYDLDGNGYISRQEMLEFLQAIYKMVGTVMKMPEDESTPEKRTDKIFRQMDKNLDGK LSLEEFIEGAKGDPSIVRLLQCDP------------------------------------ --------------DMILDLEPDDELDENPNQSDLIEQAAEMLYGLIHARYIMTNRGIAQ MIEKWQQGDFGYCPRVYCENQAMLPIGLSDIPGEAMVKLYCPKCQDVYTPKSSRHHHTDG AYFGTGFP-----------------QFVPRLYGFKIHSLAYQLQYQAAANFKMGYNNGKR MTNPKGYRRGTRYMFSRKFRTKGMIPLSTYFKVYKRGDIVDIKGNGAIQKGMPHKSYHGR TGRVYNVTQHAVGVIVNKRVRGRIIAKRINVRIEHVKHSNCRLDFLKRVEDIEKRKKAA- -------------------------------------AARATYKNVSDPEPTMDLKSMTD RAAQTLFWTELMKGLGIVLSQIFKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAICPAQAITIEAETRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEY STETHEELLYNKEKLLENGDKWEMEIAANLQADYLYRMATQAKQAKPEGKNNHESDKEQQ EAIEQIDEVQNEIDRLNEQASEEILKVEQKYNKLRQPFYQKRSELIGKIPNFWVTAFINH PQVSALLNEEDEEALQYLTKVEVHEFEDIKSGYKINFHFDGNPYFENKCISKEFHLNSSK STGITWKSGKDLTKKNQKRAHEEQESFFSWFGDHGDAGADELGEVIKDDIWPNPLQYYLA SEIEEEDE--EGLDEEEKKLTKEEELLLQDFSRNVTTKSSALFYGNALIVSAIPMWLFWR MHQMDPYVLFAVMTLISTYLISFAYKNSKFLLKHKISRKREEAVSREVMKQVSDDKKMSK KEKDERVLWKKNEVADYEATTFSIFYNNALFLVLVILASFYVLRSFSPTFNYILSISTSA GLLALFSTSTKATQGKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQT VCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNLETFGRAKTWVKELQRQ ASPNIVIALAGNKADLRMVEYEEAQAYAEENSLLFMETSAKTAMNVNDIFLAIAKKLPKN EPGVNLNEDEMAEYLASIFGTEKDKVNCSFYFKIGACRHGERCSRLHNKPTFSQTVLLQN LYINPQNTAQVVMTDMEGQEHFDEFFEEIFSELEDKYGEIEEMNVCDNLGDHLVGNVYVK FRYEEDAEKAVGDLNNRWFNGRPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKP ISRELRRQLYGRSHRTDTERSSDRRKVSSARSRSRSRSRSRSRGRMFLTRSEYDRGVNTF SPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVVLAVEKRVTSPLIEPASIEKIMEVDTHIG CAMSGLIADSRTMIDRARVEAQNHWFTYNERMSIESV---------------ADSGAMSR PFGVALLFAGIDQKGPQLYHMDPSGTFIEYDAKAIGSGSEGAQQALQDVYHKSMTLAEAK KHALTILKQVMEEKLNSTNVEMAVITPDAMFKMLTIEQLEEVIKEI-------------- ------------------------------------------------------------ --------------------------------------------VGRLENAIGWYHSHPG YGCWLSGIDVSTQMLNQQFQEPFVAIVVDPVRTISAGKVNLGAFRTYPKGYKPPEEGPSE YQSIPLNKIEDFGVHCKQYYALDVSYFKSSIDRKLLESLWNKYWVNTLSSSNLLTNADYM TGQIFDLADKLEQSEAQLGRGGFMEKKSEDKLTKATKDGCKNTIEAIHGLMSQVIKDKLF NQVGGLPRRIIKETQRLKAEPVPGIDAVPDESNARYFHVVVIGPSESPYEGGTFKLELFL PEEYPMSAPKVRFMTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPD DPLANDVAERWKVNEQQAIDTARQWTKMYA---DDLLDYDE-AVDESKDVKGTYVSIHSS GFRDFLLKPELLRSIVDCGFEHPSEVQHECIPQAILSMDILCQAKSGMGKTAVFVLATLQ QIEPVDGQVSVLVLCHTRELAFQISKEYERFSKHMNTVKVAVFFGGLTIKRDEDVLKKNC PHIVVGTPGRILALAKILNLKNIKHFVLDECDKMLEQLDMRRDVQDIFRLTPHEKQVMMF SATLSKD----------------------------------------------------- ------------------------------------------------------------ ----------------------------------------------------PPSYSDLG KSARDLFSKGFNYGFYKLEVKTKTNSGVKFTTSGSSNHDSQKVGGSLETEYKCKDYGLTF KEKWNTDNTLGTEVTIEDQLAKGLKLSFDTQFAPQTGKKSGKVKSSYKQDYVNVNCDVDF DFAGPTVHGAAVLGYKGWLGGYQMSFDKSKLTKSNFAVGYKGPDFTLHTSVNDGTEFTGS YHQKLNSQLESAVQLSWTAGSNATRLGLACKYEPDDATKIRAKLNNSMQIGLSYQHEIRD GVQLTLSSLLEGKNFNAGGHKLGLGLDLEADSVREKALTDYRKKLLEHKELEARLKEMRE QLKDFTKQYDKSENDLKALQSVGQIVGEVLKQLTEDKFIVKATNGPRYVVGCRRQIDKTK LKPGTRVALDMTTLTIMRYLPREVDPLVYNMSSEDPGDITYAQIGGLGEQIRELREVIEL PLLNPELFMRVGITPPKGCLLYGPPGTGKTLLARAVASQMACNFLKVVSSAIVDKYI--- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MPEN LRTVLVRINDEYMKSTSKKLKMIDAYLAYIVLTGVIQFVYCCLVGTFPFNSFLSGFISCV GSFVLAVCLRIQVNPQNKNEFQGISPERAFGDFIFAHVILHLVVMNFIGSLVSPSQLLPL ELVDKCIGSRIHIIMKSDKELVGTLLGFDDFVNMVLQDVTEFESTPEGRRVTKLDQILLN GNNITMLVPGGEGPDVIDHYENPRNVGSLDKNDSDVGTGLVGAPACGDVMKLQIKVDEDG KIVDAKFKTFGCGSAIASSSLATEWIKGKSINDAGKIKNTDIAKELSLPPVKLHCSMLAE DAIRAALNDYKKKS-MLVLVLGDLHIPHRSSTLPAKFKKLLVPGKIQHILCTGNLCTKES FDYLKTLASDVHVVRGDFDENMTYPEQKVVTVGQFRIGLCHGHQVVPWGDTESLAIVQRQ LDVDILITGHTHKFEAFEHENKFYINPGSATGAFSALDSGITPSFVLLDIQQATVVAYVY QLIGDDVKVERIEYKKMGKFMKPGKVVLVLGGRYAGRKAVIVKNYDEGSPDKPYSHALIA GVDRYPRKVTKRMGKKKIKQRSKLKAFVKVANYNHLMPTRYSVVSLDKAVVNKDSFRDPA LRRKARRDAKTKFEEKYKTGKNRWFFQKLRFERTFIMIKPDGVHRGLVGEIIKRFEQRGY KLVALKFVHASEEHLKKHYADLAGKPFFPGLIKYMSSGPLVPMVWEGDAVKTGRVMLGET NPLASKPGTIRGDFCIQVGRNICHGSDSVESANKEIDLWFNADALIDWSPVSNPWVYEKE APAPPKA--EANAKALKAKKAVLKGVHSHKKKKIRTSPTFRRP-TLRLRRQPKYPRKSAP RRNKLDHYAIIKFP---------------------------------------------- ------------------------------MPSKQRMRIANDKASKNVGNRGNVPKTLKS VDEKYPVGPWMLALFVFVVCGSAVFQIIQSIR-XXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMIRFI LIQNRAGKTRLAKWYMHFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIVYRRYAGL YFCICVDVSDNNLMYLEAIHNFVEVLNE-------------------------------- -----------------TPTIFSKIIDKTIPAEILHEDDQCLAFRDVSPVAPTHFLVIPK KIIPQLSVDESLLGHLMLTAKNVAKQTDGYRVVINDGVNGAQSVYHLHLHVIGGRQMSWP PMGGFLSYFSGWFGSKERRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVTYKN LKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSMDRDRIGISKQELVSMLEEEELKKAI LVVFANKQDIEGAMSVTEVANALGLSALKNRKYQIFKTSAIKGEGLDEAMEWLANSLQNQ KGLYFHIGETEKKCFIEEIPDETMVVGNYRVEVYDKVQNNYVPTVSGLGMHAEVRDPEDK VILSRMYAADGRFIFTSHSAGEHLICLHSNSTAWFGGGQLRVHLDIQVGEHTNDYQQIAA KDKLTELQLRVRQLLDQVEQITKEQNYQRYREERFRQTSESTNQRVLWWSIAQTVILLVT GFWQMRHLKSFFEAKKLV------------------------------------------ -----------------------VVYPVKYKAIVFRPFKGEVLDAVVTQVNKVGLFTEIG PLSCFISRHSIPADMEFDPNSNPACYKTKDEDMVIQQDDDIRVKIVGTRVDATDIFAIGT LMDDYLGLVSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMAKKTY DLLFKLLLIGDSGVGKTCLLFRFSDDAFNTTFISTIGIDFKIKTVELRGKKIKLQIWDTA GQERFHTITTSYYRGAMGIMLVYDITNAKTFDNISKWLRNIDEHANEDVEKMILGNKCDM EDKRQVSK---------------------------------------MPQNEHIELHRKR YGRRLDYHEKKRKKESRMAHENAAKAKKLRGLKAKLYNKKRHSEKVQMKKTIKMHEERKT KQKKTDEVPEGAVPAYLLDREGQSRAKVLSNMIKQKRKEKAGKWDVPLPKVRGVSEAEAF KVVTSGKRGKKAWKRMVTKATFVGEAFTRKPPKFERFIRPMALRYKKAHVTHPELKATFC LPIIGVKKNPSSPLYTSLGVMTKGTVVEVNVSELGLVTQGGKVVWGKYAQITNNPENDGC INAVLLVMAARPLITVYNEKGESTGTNVTLPAVFRAPIRPDIVNFVHSEMRKNARQPYAV SEKAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRR INVNQKRYAICSAIAATGIPSLVMSKGHRVEQLPEVPLVLSDNVESYKKTKEAMGLLKRI KAWNDIEKVKSSRRFRAGKGKMRNRRRIQRRGPMVIYNQDNGICQAFRNIPGITLLNVSR LNLLKIAPGGHVGRFCIWTESAFKKLDNIYGTWRKPSTEKSNYNLPMHKMTNTDLSRLLK SDEIQSVIRAPKKFMKKKELKKNPLRNVRTMIRLNPYAAVQRRNAI-------------- ---------------------QELATKTLQIQSKRFYLDVKQNRRGRFIKIAEVGSGGKK SRLLLAMSTAAEFRDHLTDFSEHYASLGPPNPDNLPEDGKLKSEVMIKDNRRYYLDLKEN QRGRFLRVSLRSQQRSQIAIPAQG------------------------------------ -MFYFDVGQNRRGVFMRISETNFRTAITIPEKSWARFRDILSDFVDKTEKKMRDAQMRAQ INQSLVETGERDKLKELLRIRLVECGWRDQLKHHCKEVVRQKGLEHITVDDLVAEITPKG RALVPDQVKKELLQRIRTFLAQQ-------AKPEDLMNMQHCNLLCLPENYQMKYYFYHG LSWPQLSYVAEDEKGKIVGYVLAKMEEDPEDCVPHGHITSLAVKRSHRRLGLAQKLMDQA SRAMTECFNAVYVSLHVRKSNRAALNLYANTLGFTISEIEPKYYADG------------- ----MAHTILLVQPGRKPESRTYSDYESINECLEGVCKIYEEYLKRINANSPSITYDISQ LFEFIDQLADLSCLVYQKSTATYEPHNKDWIKEKIYDLLRRQAGR--------------- ---TYPLIRHSDMNEEMRTEAMELCVTACEKFSNNNESAAKMIKETMDKKFGASWHAVVG EGFGYELTHEVKNLLYMFFGGTLAICIWKCS-------------------KRSRRHRGKV KCFPKDDKTKPVHLTAFLGYKAGMTHILRDVDRPGSKVNKKEVVEAVSIVETPPMVIVGV VGYIETPRGLRTFKTIFAEHLSEECRRRFYKNWYRSKKKAFTKSSKKWQDAAGQKEIERD FAKMKKYCKVIRVLAHTQMKLLKKRQKKAHIMEIQ------------------------- ------------------------------------------------------------ -----------NKKIYRIGQGIHTKDGKVIKNNASTEVDITEKSITPMGGFPHYGEVIND FLMIKGAVVGCKKRVLTLRKSLLVQTKRIALEKIRLKFIDTSSKFGHGRFQTSEEKKSFM ------MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLG LWDTAGQEDYDRLRPLSYPQTDVFLICFSLISPASFENVRAKWYPEVSHHCPNTPIILVG TKLDLREDKETQEKLKEKKLSPITYPQGLAMAKEIGAVKYLECSALTQKGLKTVFDEAIR AVLCPKPKAKTKRRCFVLIFDPSMKKKKKKKTPFDLDAALDDLNLDDNLTKKKKKKKKPF DLSELDEALPKEDKNFSTKKKKINSDRDYTYEELLKRVFDIMREKNPDMVAGERKKFNTK PPRVMRVGTKKTSFSNFKEICKALHRQPEHLLAFLFAELGTSGSIDGNDQLIIKGRFQQK QIENVLRSYIKEYVTCHTCKSRDTLLQKDTRLYFLQCETCGSRCSVTSIKSGFQAFTGKR AAIRAKTTFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGK DYSIHRLILGTHTSDEQNHLLIASVQLPNDNAQFDASHYDSEKGEFGGFGSVSGKIEIEI KINHEGEVNRARYMPQNPCVIETKTPSSDVPEFNY------------------------- ------------------------------------------------------------ -----------------------------------------------------------A LWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQSAEDA EDGPP------------------------------------------------------- --------RARVYADINTHRPREYWDYESHVVEWGQQDDYQIVRKLGRGKYSEVFEAINV TNNEKCVIKILKPVKKKKIKREIKILENIRGGTNVIALIAIVKDPVSRTPALIFEHVNNT DFKQLYQTLTDYDIRFYLFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLA EFYHPGQEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPFFHGHDNY DQLVRIAKVLGTEELYEYIDRYQIDLDPRFNDILGRHSRKRWERFVHSENQNLVSPEALD LLDKLLRYDHAERLTAREAMEHPYFYPIVKEAVPETLLKKRKQNAEKNREKRKEIFKRAE KYVKEYRIKERDQIRLARQAKKSDNFYVPPEAKLAFVVRIRGINGIHPRPRKVMQLFRLR QINNGTFIRLNKATIHMLRICEPYVTWGFPNLKSVREMIYKRGFGKIDGQRVALTNNAVI EQALGKFNIICMEDLIHEIFTVGPHFKEAN------------------------------ ------------MEFMLLFSRQGKLRLQKWYVAHPDKVKKKITRELITTILARKPKMCSF LEWKDLKIVYKRYASLYFCCAIEPKDNELLTLEIIHRYVELLDKYFGSVCELDIIFNFEK AFFMLDELLLGGEVQETSKKNVLKAIAAQDLLQEETPQGFFEDHGLGMSKAHPPELKKYM DKVLTLKLNGARSLTGTLRGFDPFMNLVMDEAVEETKSGEKNQIGMVVVRGNSIVLLESQ ERVEFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTI RLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFQQTSKWIDDVRTERGTDVIIM LVGNKTDLSDKRQVSTEEGERKAKELGVMFIETSAKAGYNVKQLFRRVAAALPGMEQTEK KP-TDIHLHDP--EPRR-----------------------------------KFIRDVVR EVCGFAPYERRCIELLRISKDKRALKFCKKRLGAHVRGKRKREEMQNVIQMMRKA-VDEH TKKTLAQIPLLKTRAGPRDAELWVQRLKEEYMTLIKYVESNKKADNDWFRLESNKDGTRW FGKCWYIHELLKYEFDVEFDIPVTYPTTAPEIA--------------------------- --------------------------------------VFDQFEFLDDVRRMNKRQLYYQ LLNFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNYKEEPIRVGE IVVFKVEGREIPIVHRVLKVHEKDDGAVKFLTKGDNNQVDDRGLYAPGQLWLDKKDVVGR ARGFVPYVGIVTILMNDYPKFKYAILALLGLFVLIHREMSTMNPEYDYLFKLLLIGDSGV GKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYR GAHGIIVVYDVTDQESFNNVKQWLQEIDRYASEHVNKLLVGNKSDLSTKKVVDYTTAKEY SDQLGIPFLETSAKNATNVEQAFMTMAAEIKNRMGPAPSASSVKINQSTPVKQGGGGCC- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------STFLKLAGPQLVQMFIGDGA KLVRDAFALAKEKAPAIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNAN IKVIAATNRVDILDPALLRSGRLDRKIEFPTPTEEARARILQIHSRKMNVSTEVNYEELA RCTDDFNGAMCKAVCVEAGMIGLRRGATELSHEDYMDAIMEVQAKKKANLNYYAXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX------------------------------------------- -----------------------------------------------------------R VFNGSGKPVDKGPSVLAEDFLDIQGQPINPWSRIYPEEMIQTGISAIDGMNSIARGQKIP IFSAAGLPHNEIAAQICRQAGLVKLPGKSVMDDHEDNFAIVFAAMGVNMEIARFFKQDFE ENGSMENVCLFLNLANDPTIERIITPRIALTTAEFLAYQCEKHVLVILTDMSSYAEALRE VSAAREEVPGRRGFPGYMYTDLATIYERAGRIEGRNGSITQIPILTMPNDDITHPIPDLT GYITEGQIYVDRQLQNRQIYPPINVLPSLSRLMKSAIGEGMTRDDHSDVSNQLYACYAIG KDVQAMKAVVGEEALSQEDLLYLEFLQKFEKNFIAQGHYENRTI---------------- --------------------GPGFVGIRFCQECNNMLYPKEDKENRILLYACRNCDYQQK ADNPCIYVNKIEHEIDELTQIIADVIADPTLPRTEDHPCEKCGHKEAVFFQSQTRRAEEG MRLYYVCTLPSCSHRWTEKPPYKVADMSLADWGRKALDMAENEMPGLMMMRRVYGPKKPL KGARIAGCLHMTVQTAVLIETLTDLGAEVQWSSCNIFSTQDHAAAAIAKTGVPVYAWKGE TDEEYIWCIEQTLVFADGKPLNMILDDGGDLTNLVHSKYPQYLKGIKGLSEETTTGVHNL YKMVKSGELKVPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGRVAVVAGYGDV GKGSAAALRAFGARVLVTEIDPINXLQAAMEGYEVTTMDEACKISRVFVTTTGCKDIIKS EHMTQMMEDAIVCNIGHFDCEIDTAWLNANCVKKDNIKPQVDRYTMPSGRHLILLAEGRL VNLGCAMGHPSFVMSNSFTNQVLAQIELWTKADQYSLDVHILPKKLDEEVAAAHLEHLGV KLTKLSDDQAQYLGIPQEGPFKPDHYRY-----QPPANTVEEPLDLIRLSLDERIYVKMR NDRELRGRLHAYDQHLNMIMEDVEETVTTIEIDEETYEEIYKSTKRNIQMLFVRGDGVIL VSPPMRTMSSGNVENLSPQIIRQVCRELSELVSDPPEGIKV------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------EETSCEFGSTKYFALCGFGGVLSCGITHTAVVPLDLVKCRIQ VDPAKYGGLIKGFKVTLAESGVRELGKGWAPTLFGYSAQGLCKFGFYEVFKNVYSNLIGE ENTFLWRTSLYLAASASAEFFADIALCPMEAVKVRIQTQPGWANTLREGFPKLMAEEGMG GFYKGIVPLWGRQIPYTMMKFACFERTVEALYKFVVPKPRADCTKSEQLIVTFVAGYIAG VFCAVVSHPADVIVSKLNKDKNATFTGVAKDLGFMGMWNGLGPRIIMIGTLTALQWFIYD SVKVYFRLPRPPPPEMPESLKLKLEHWLQEHYAGFALYPIIPLALAYVLDTALCMVMLHT HQGLSGVAGDYVHFSILAFGSLCHLNYFDVGFGNLVQQIYTKLNEQQEEDASELVFPKEF ENAETLLISEVKRKQQNECAEEEQELSEVFTKTLNYSQRFSKFKNRETIGAVXSLLMQKK LHKFELAALANLCPETAEEAKALIPSLEGRFEDDELQQILDDIQTKLSFQYMGQPHLARQ DLENLDITTLNPLSPEVISRQATINIGTIGHVAHGKSTVVKAISGVQTVRFKNELERNIT IKLGYANAKIYRCDAPDVQRPQCYTSKGSSHPDEFPCEFSNSGKYKLVRHVSFVDCPGHD ILMATMLNGAAIMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHIIILQNKIDLVKESQ AQDQYQQILRFVQGTIAEGAPIVPISAQLKYNVDAVCEYITKKIPIPVRDFLSLPRLIVI RSFDVNKPGCEVEDLKGGVAGGSILRGVLKVGQEIEVRPGIVAKDSEGKLTCQPIFSRIV SLFAEQNDLQYAVPGGLIGVGTKIDPTLCRADRMVGQVLGAHEALPDIYTELEIFYFLLR RLLGVRTEGGKKGAKVQKLTKYEILMVNIGSLSSGGRVLGEKGDMAKIQLTSPVCTEEGE KIALSRRVEKHWRLIGWGKIRRGVKI---AELLLDSNIRLWVFLPIVVITFLVGIIRHYV TILLSSEKKVDLTQIADSQALIRSKTLRENGRFIPKQSFLMRKEFFNNETTGYFVRNPMT DPAMMTDMMKGNLTNVLPMIVIGGWINWAFSGFLTTKVPFPLTL---------------- ------------------------------------------------------------ --------------------MFLWDWFAGILNFLGLYKKSGKLVFLGLDNAGKTTLLHML KDDRMAQHVPTLHPTSEELSMGGMRFTTFDLGGHAQARRVWKDYFPAVDGIVFLIDAVDR QRFPEAKAELESLLTDEQISHAPVLILGNKIDIPGAASEDEIRHMFGLHGQCTGRGTVSR NELRPLELFMCSVLKRQGYGEGFRWMAQYINXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPN IKLQSSDGEIFEVDVEIAKQSVTIKTMLEDDEDEEEAVPLPNVNAAILKKVIHWCTYHKD DPPPPEDDENKEKRTDDISSWDAEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMI KGKTPEEIRKTFNIKNDFTPAEEEQVRKENEWCEEKNKRVSKGGKKGGKKKIVDPFTKKD WYDVKAPSMFNIRQIGKTLVTRTQGTKIASDGLKGRVFEVSLADLQTDEVAFRKFKLVAE DVQGRNVLTNFHGMNLTTDKLRSMVKKWQTMIEANVDVKTTDGFLLRLFCIGFTKKRPNQ IKKTCYAQHTKVRAIRKKMVEIMHREVSANDLKDVVGK---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------EFELMSYRMQSNAKPLIWVESVFERHSHSRIEVMIKVKSQFKRRSTANN VEVEVPIPSDADSPKFKTTVGNCKWFPERNAVVWYIKSFPGCKEHIMRAHLKLPSVEAED QEGRPPVYVRFEIPYYTVSGLQVRYLKIIEKRGYQALPWVRYITQNGDYQVR-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -NLTATVAQSELDMDNVKTILGEYRIHNADITLRYDATTEDLIDVIEGNRVYIKCIYVLN KIDQISVEELDIIYKIPHCVPISAHHKWNFDDLLEKMWEYLQLTRIYTKPKGQLPDYEAP VVLKDGQSTVEDF----------------------------------------------M AKHHPDLIFCRKQPGVAIGRLCEKCDGKCVVCDSYVRPCTLVRICDECNYGSYQGRCVIC GGPGVSDAYYCKECTIMEKDRDGCPKIVNLGSAKTDLFYERKKYGFKKRPLLPPISGDKL VNKSDMRKIPVPANRYTPLKENWMKIFSPVVEHLHLQIRFNLKTRNVEIKTCKETKDISA LQRAADFVKAFTLGFEVDDALALLRLDELYLESFEITDVKPLKGDHLARAIGRIAGKGGK TKFTIENTTKCRIVLANEKIHVLGSFQNIKVARTAICNLILGSPPSKVYGNMRAVAARST ERRIKSAKPVVELDGDEMTRIIWAMIKDKLIFPFVDVECLYYDLGLPYRDQTDDQVTIDA AHAILKHSVGIKCATITPDEERVEEFKLKKMWLSPNGTIRNILGGTVFREPIICEKIPRL VPGWKLPITIGRHAFGDQYKATDFVAKGAGKFQMKYIPADGSPTVYDVFDFKE-GGVCMG MYNVDESIRGFAHSCMQYAIKKKWPLYMSTKNTILKRYDGRFKDIFEEIYQQHYRKQIED LGIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDVIAQGYGSLGLMTSVLMCPDGK TIEAEAAHGTVTRHYREHQKGNPTSTNPVASIFAWTRGLEHRANLDGNKDLAHFCQTLEQ ACVDTVDNGQMTKDLAGCIYGLKNVTPSQYLYTEDFLDAIKE------------------ ------------------------------------------------------------ ---------------------DEARQELHRIINDREMRDAIILIFANKQDLPDAMKPHEI QEKLGLTRIRDRNWYVQPSCATSGDGLYEGLTWLTSNAKSFGDLKSDSGLATLNDFLADK SYIVGYQPSQADSVVFDGVTSPGNKYAHALRWYNHIKSYAGEKASFPGAKKALSEYGPAG GADDDDDDDIDLFGSEAEKLKASRLAAYAEKKSPALIAKSNIILDVKPWDDETDMAEMER LVRTVSTDGLLWGASKLVPLAYGIKKLQICCVVEDDKVGTDFLEEEITAFEDVVQSVDIA AFNKI------------------------------------------------------- ----------------GTGKTAIAMGMAQALGQDTPFTAIAGSEIFSLEMSKTEALTQAF RKSIGVRIKEETEIIEGEVVEVQIDRPATGTGAKIGKLTLKTTEMETIYDLGQKMIESLT KEKVQAGDIITIDKATGKITKLGRSFTRARDYDAMGPQTKFVQCPEGELQKHKEVVHTVS LHEIDVINSRTQGFL--------------------------------------------- ------SFLNRALETDMAPVLIMATNRGITRIRGTNYQSPHGIPIDLLDRLLIISTSPYE EKEIKQILKIRCEEEDVEISDDALTVLTRIGMETTLRYAIQLITTANLTCRKRKGAEVGV DDIKRVYSLFLDESRSTQFLKEYQQEFMFHEMAEFDLTTRLGQYLDRHLVFPLLEFLSVK KIYDEHEMLSGKLDLLSSTNMVDFAMDVHKNLFPGREVPQTLRDKRIEVVGELKRLQVET EPITKIFEDAEVMMESARDGRQLYESLSKNYGFRADMIDLLYTHAKFQYECGNYSGAADY LYFVRVLIPPGDKQYLNVLWGKLASEILMQDWEMALSDLESLKEVIETALQALQHRTWLI HWSLFVFFNHPKGRDLIIDMFLYEPQYLNAIQTMCPHILRYLTTAAITNKNVLKDLVKII QQESYTYKDPITEFLECLFVHFDFDRAQKKLRECETVLVNDFFLVACLDDFIENARLFIF ETFCRIHQCITINMLAEKLNMKPEEAERWIVNLIRNARLDAKIDSKLGHVVMGQQAVSPY QQVFEKTKALAYRSQVLVMKIENKLGAKTMGVQVETTAPGDGVSFPSKGQTVHVHYTGTL TNGKKFDSSRDRGRPFTFKLGAGQVIKGWDEGVAQMSKGQRAKLTCSPDYAYGEAGAGGV IPPNATLVFDVELI---MPKYYCDYCDTYLTHDSPSVRKTHCNGRKHKENVRIYYQKWLE EQVQKLVDDTTAQFKADSAAGK----SAAPAAPPVAPGGAPTGPMMPMMGP--GGSMPPM RPPMGPMGGPMGAMGGP----LERDIQRAIELLEHLQKSGELARLAALQKVLQSDFCTAV REVYEHVYETVDISGSPEVRANATAKATVAAFAASEGHAHPRVVELPKTEEGLGFNVMGG KEQNSPIYISRIIPGGVADRNGGLKRGDQLLSVNGVSVEGEPHEKAVDLLKAAQGNVKLV VRYTPKVLEEMEARFDKQRTARRRQLACLIGAVVCEEVVFFQEAFWEERWVESSHKGSEQ GAFKWSAGKFYGDADDDKGIQTSQDARFYGISHKFEEPFSNQDKTLVIQFTVKHEQNIDC GGGYMKLYPSELDQKDLHGDSPYLIMFGPDICGPGTKKVHVIFTYKGKNLLTKKDIRCKD DVFTHLYTLIVRPDNTYEVKIDNKKVESGELEKDWDFLPPRTIKDPEAKKPEDWDDDEKI DDPEDTKPEDWEQPEHIPDPDAKKPDDWDDEMDGEWEPPMIDNPEYKGEWKPKQIPNPNY SGVWVHPEIDNPEYSADSNLYRYDDISAVGFDLWQVKSGTIFDNILITDDEKLAEQVGED TWGSTKDAEKKMKDEQDEVERKQREEEEAKRKEEEGEDEDE---MDCALPEPTLYTVKAI MILDNDGNRLVAKYYDDTFPTVKEQKNMFNKTHRANAEIIMLEGLTCVYRSNVDLYFYVI GSAQENELILVNVLNCFYDAISHMLKKIVEKRSLLDNLDGVFM----------------- -------------------------------------MNIFRLCGDLSHLLAILLLLVKI WKTRSCAGVSGKSQIMFAMVFATRYLDLFTSFISLYNTCMKVFFIVSSLVTVYLMYFKFR ATYDSNHDTFRMEFLVVPVAGLAFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGE AESITSHYLFALGSYRALYILNWAYRWYFEGFFDLIAVVAGCVQTVLYCDFFYLYVTKVW KGKRL------------------------------------------------------- ----------------------------------------------------------EV LMENFRRAIGLRIKETKEVYEGEVTELTPVETENPMGGYGKTVSHVIIGLKTAKGTKQLK LDPSIYESLQKEKVETGDVIYIEANSGAVKRQGRSDTYATEFDLEAEEYVPLPKGDVHKK KEVIQDVTLHDLDVANARPQGGQDIMSMMGQLMKPKKTEITDKLRKEINKVVNKYIDQGI AELVPGVLFVDEVHMLDIECFTYLHRALESTIAPIVIFATNRGRCTIRGTDDVVAPHGIP LDMLDRLMIIRTLPYSQEEMVQITRIRAQTENISISDDSLLLLGEIGVKTTLRYAVQLLT PAHLLCKINGKELIAREEIEEINELFYDAKSSAKILAEQEDKYMKDFEVDEEGDQGLMKL KEKVKKRKGRGFPTRIEVEEYEGMEVDGPGPQRSVE------------------------ ------------------------------EAQQAAENLNGSELLGQKINVDWSFVRGPT AKKMNYQFYRNTTLGHTLQESLDELIQCGQITPPLALKVLFHFDKAINQALATRTKTRIN FKGKLNTYRFCDNVWTFVLNEVEFRHVDKVKIVACDGKSTFLFTSESVGEGHPDKICDQV SDAVLDAHLKQDPNAKVACETAAKTGMIMLLGEISSKAHVDYQTVVRDAIKYIGYDDSAK GFDYKTCNVLSALEEQSPDIAHGVHVGRTEEEVGAGDQGLMFGYATDETEECMPLTVVLA HKLNAKVAELRRNGGLPWARPDSKTQVTVEYRMEKGACIPIRVHTVVVSVQHAEEISVEE LRTQVMEHVVRKVIPEKYLDAKTVFHIQPSGRFVIGGPQSDAGLTGRKIIVDTYGGWGAH GGGAFSGKDFSKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVAEPLSIFVTSYGT GVKHDSELLRIVKTNFDLRPGKIVKDLDLKKPIYQKTAAYGHFGRSDFSWEQPKKLIFMA GSALRRLMAEYKQLTLNPPEGIVAGPMNEENFFEWEALITGPEGTCFEGGVFPARLTFPA DYPLGPPKMKFTCDIFHPNIYPDGRVCISILHAPGDDPMGYESSA--------------- -------------------------------------------MRLEKCYYCSSTVYPGH GIVFVRNDSKVFRFCRSKCHKGFKQKRNPRKVRWTKAFRKSAGKELTVDSSLEFEKRRHV PVKYQRELWNKTVNAMKRIEEIKTKRQAQFIKNRLKKGKELRKQQDIKDVEKNIHLIRAP GAKMAVYKVVMVRHGESAWNKENRFCGWYDADLCPSGEEEAKNAGKMLKEGGYEFDIAFT SVLKRAIKTLFHVQDALDLHWIPVERHWRLNERMYGALQGLNKSETAQKHGEDQVKIWRR SFDVRPPDVDLTSEHFPGNDAKYKYVDKQLMPRAECLKDTIVRVLPYWYDNIVPAILKGQ RVLISAHGNSLRSLVKYLDNMSDADIMGMNIPTGIPLVYELDKDLKPVKHYYLASEEQVK AAMDKVAAQGKAK----------------------------------------------- -RGDLANVRIGRHCVISKRAVIRPPFKKFSKGVAFFPLHIGDHVFIGEDSIINAAQVGSY VHIGKNCVIGRRCVLKDCCAIADNTVLPPETVVPPLTIFSGSPG---------------- ------------------------------------------------------------ ------------------------------------------------------------ --PFPTSFESIVKKIHRYLFHVLAHIYQSHYKEMLCLKLHPHLNTVFQHFMSFNRQFELI DAKEVEILDDLFIKL----MGIDICHKKERKVHRTEPKSDDIYLRLLVKLYRFLARRTNA KFNKIVLKRLFMSKTNRPPMSIARLVRNMKKPGRESKIAVIVGTITDDVRILDIPKLRVC ALRVTERARTRILKNGGEIMTFDQLALKAPKGQNTVLIQGPRKARKAFRHFGTAPGVPHS HTAPFVRAKGRKFE---------------------------------------------- ------------------------------------------------------------ --------------KRFKVYVTQESGIQMGKDLDNLGIPTVVILDAAVGYIMEKIDLVIV GAEGVVESGGIINKGTYTMALSAKEMNKPFYVVAESFKFARLYPLN-QDVPNEFKYQASR EHPMVDYTPPQYLTLLYTDLGILTPSAI---------MIIPIRCFTCGKVIGNKWEAYLG LLQAEYTEGDALDALGLRRYCCRRMLLAHVDLIEKLLNYAPLEKXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKARGQLKEYKVIGRAHPTDKCRV PPLYQLRIFAPDPITAKSRFWYFCGLLRKMKKTQGEIVLCQQIYEKHPETIKNFGIWLRY NSRSGTHNMYREYRDLTTADAVTQCYRDMGARHRARACSIQIMRVAVIPSEKCRRGHIKQ FHDSKIKFPLPHRISKRLHAPRFT--------SARDQMDGFWRKNEGRPVSPWINYKWEL PMLTSLGHRFTGISMGLVLYGGAMGLYLAPENVTHYVDALAAMEMGPMVWFPLKSLVAFP LIYHYINAIRHYYWDFKGGYEVAVQLKTGVAAAGGASY-XXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXX------------------------------------------------------- ----------------------------------------------------------VS GSFDESVRTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTG- ------------------------------------------------------------ ------------------------------------------------------------ -------YQFFIGVALLDYVTPYMIFFKDGLEMEK-MAVEFADGVIIGADSRTTTGAYIA NRVTDKLTKITDYIYCCRSGSAADTQAIADIVSYHLNFHKMEIDAEPAVKTAATVFQELC YSYRDQLSAGIICAGWDAKKGGQVYSIPLGGMCVRQPFSIGGSGSTYVYGYVDAQYKEGM SKAECIDFCTKTLALAMSR----------------------------------------- ----------------------------------------------PELDDLEPNMEDNE DAESVKSEVKLGKLQFSLDYDFQKGELTVGVIQAADLPGMDMSGTSDPYVKVYLMPDKKK KFETKVHRKTLNPVFNETFMFKVPYAELGTKTLTFAIYDFDRFSKHDQIGLVQVPMNSVD LGRVVEEWRDLTSPEADNEK-NKLGDICFSLRYVPTAGKLTIVILEAKNLKKMDVGGLSD PYVKIALYQGTKRLKKKKTTIKKRTLNPYYNESFTFECPFEQIQKVTAIVTVVDYDRIGT SEPIGRVVLGCNATGTELRHWSDMLANPRRPVAQWHTLQEMPEKNMVLADLGRKITTALR SLSSATVINEEVLNSMLKEICKALLEADVNIKLVKKLRENVRSVIDFDEMAAGLNKRKMI QSAVYKELVKLVDPGVKAWTPTKGRSNVIMFVGLQGSGKTTTCTKLAYYYQRKGWKTCLV CADTFRAGAFDQVKQNATKARIPFYGIDTSGRHKQEDSLFEEMLQVSNVTPDNIVFVMDA SIGQGCESQAQAFKDKVDVASVIITKLDGHAKGGGALSAVTKSPVIFIGTGEHIDDFEPF KVQPFVSKLLGMGDIEGLIDKVNELKLDDEELMKKLKH---------------GQFTLRD MYEQFQNIMMSIMSYNGAAVVAMKGKDCVAIASDRRFGIQAQTVGFDFQKIFEMSPHLYL GIPGLATDVQTVSQRLKFRLNMYQLRENRPIKPHTFMSMVSNLLYERRFGPYFVEPVVAG LHPKTMEPYVASLDLIGCPMETEDFVVSGTCTEQLYGMCESLWEPNMEPDDLFECISQSL LNAVDRDAVSGWGIIVHIIEKDKVTTRTLKGRMDMTSKDYYFDSYAHFGIHEEMLKDEVR TLTYRNAMMHNKHLFRGKVVLDVGCGTGILSMFAAKAGAKMVIGIECSSIVEYAEKIVAS NKLDDVVKIIRGKVEEVKLPEGIEKVDIIVSEWMGYCLFYESMLSTVLFARDKWLASDGM IFPDRATLYLCAIEDRTYKDEKINWW---------------------------------- --KEVDMYTIKNEDLSFSSPFHLQCRRDDYIQALVSFFNIEFTKCHKRTGFSTAPECRYT HWKQTDDYITVKQGEEIYGVVNIKPNAKNPRDLDFHIDIDFHGELSEITESNHYKMR--- -----------------LDEYPRCFIVGADNVGSKQMQNIRIALRVLMGKNTMMRKAIRG HLENNPALEKLLPHIKGNV----------------------------------------- ------------------------------------------------------------ ------------------------------------------GYPTVASIPHVLINGFKN LLAVAAVTEIDFKEAE-------KGKLLAVIGDEDTCTGFLLGGIGELNRQRQPNFLVVD KNTSVSEIEEAFKVFSSRSDISIILINQNIAEMIRHILDSYSQPIPAVLEIPSKDHPYDA SKDSILRRAKGMFSADDLKGNEASLPLELCSTFDADEIKRLGKRFRKLDLDNSGSLSIDE FMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGMSQFSVKGDKESKLRFAFKIYDMD KDGYISNGELFQVLKMMVGNNLKDAQLQQIVDKTVIHADTDGDGKISFEEFCSVVGSMDV HKKMVVDVMTFITSWEEFAKAAERLYLSDPTKCRFVTQYRHKDGRLSVKMTDDKVCLQYQ TEHAQDVKKIEKLTSQLMRHMASKE---------------------------NTIQCLEK AYIKDLVPAREYTAACSKLLVQYKAAFKQVEGNEYPSVEVFMKKLKLDCPAALERIKEDR PITIKDDKGNTSRCIADIVSLFITIMDKLRLEIRAMDEIHPDLRDLSDNMKRLSLLPEDF DGKSKVDSWLSTLGSMQASDELDDSQVRQMLFDLESAYNDFNRVLHN------------- -------EKGKKEAVAATALTHALVDHLNSGVAQAYVNQKKLDTETKILQANASQFAKQT MLWLKLVEDFNTSLKEIGDVENWARSIETDVRTISSALEYAYKARVVTKEIKGDKNGGSR KVRINRMPRYYPTEEYPHKLASPFKAHKRNLRPSITPGTVLILLAGRHKGKRVVFLKQLG SGLLLVTGPYHLNGCPLRRINQIYCIATKTKIDISSVNIPEHVNDAYFRRAKLQKPKHAE GEIFDTKKESYSVSDERKKDQVDVDKQLLDVIRKHAEKKTLFGYLGAMFSLQNHMY---- --MEWLFGRKKTPQEMLRQNQRALTKAMRELDRERAKMEQQEKKIIADIKKMAKQGQMDA VKIMAKDLVRTRRYVKKFMLMRANIQAVSLKIQTLKANDSMAQAMKGVTKAMATMNKQMK LPQIQKIMMEFEKQTEIMDMKEEMMSDAIDDAMGDEDDEEESEQIVNQVLDELGLQMTDQ LTDIPGVGQSPSKTPVGVSDADADLEARLDNLRRQ--YCDFCLGDEEENKKTGTREELVS CADCGRSGHPSCLQFTPNMIISVKKYPWQCIECKSCGLCGTSDNDDQLLFCDDCDRGYHM YCLTPPLSEPPEGSWSCHLCIAEFYGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------TARA FAVVASALGIPSLLPFLKAVCRSKKSWQARHTGIKIVQQIAILMGCAILPHLKNLVEIIE HGLVDEQQKVRTITALALAALAESATPYGIESFDSVLKPLWRGIRQHRGKGLAAFLKAIG YLIPLMDAEYANYYTREVMLILIREFQSPDEEMKKIVLKVVKQCCATDGVEPQYIKEEIL PPFFKHFWNQRMAMDRRNYRQLVDTTVEIANKVGAAEIVSRVVDDLKDESEQYRKMVMET IEKIMGNLGSADIDSRLEEQLIDGILYAFQEQTNEDVVMLNGFGTVVNALGKRVKPYLPQ ICGTILWRLNNKSAKVRQQAADLIARIAIVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLG SILGALKAIVNVIGMTKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGAEFVS AREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVC TTVAIAIVAETCSPFTVLPALMNEYRVPELNVQNGVLKSLSFMFEYIGEMGKDYIYAVTP LLEDALMDRDLVHRQTAMAAIQHMALGVYGFGCEDALVHLMNHVWPNIFESSPHVVQAFM GAVEGIRVGMGPSKILQYTLQGLFHPARKVRDVYWKVYNTVYIGAQDAMIPSYPRIQDDD KNSYVRYELDYIL----------------------------------------------- --------------------------NFKLGNYGEMMNRYKQLLTYIKSAVTRNYSEKSI NSILDYISTSKQMDLLQNFYETTLEALREAKNDRLWFKTNTKLGKLYFDREEFAKLQRIL KQLHQSCQTDEGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPL IMGVIRECGGKMHLREGEYEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGIN PFDSQEAKPYKNDPEILAMTNLVSAYQNNDINEFEKILKMNRKNIMEDPFIREHIEDLLR NIRTQVLIKLIKPYTRIHIPFISKALNIDVSEVENLLVSNIL------------------ ------------------------------------------------------------ -----------------------------ENYFASQRDNIFRNVEVLIYVFDVESRELEK DMHYYQSCLEAILQNSPEAKIFTLVHKMDLVQDDQRELIFNERKEDLRRLSRPLATSIWD ETLYRAWSSIVYQLIPNVEALETNLKNFANIIDADEVLLFERATFLVISHCQQQPHHDVH RFEKISNIIKQFKLSCSKLAASFQSMEVRNSSFAAFIDVFTSNTYVMVIMSDPSIPSAAT LINIRNARKHFEKLERVEQ----------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------IPLHVLSLMATGRFSHRIYIAYCTVYAVGT ILSMQISFVGFQPVQSSEHMAALGVFGLCQIHSFVDYLKSKLSREQFEILFRSLVLLAAV VIGLATGKISPWTGRFYSLLDPSYAKNNIPIIASVSEHQPTTWSSFYFDLQMLVFMFPAG LYFCFKELSDANIFIIMYGITSIYFAGVMVRLMLVLAPVMCILAGIAVSSTLTTYMKNLD VGKKADSNYPLKNEIATGVVLLVTFFLVTYTFHCNWVTSEAYSSPSIVLSARSGDGGRII FDDFREAYYWLRHNTPEDAKVMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMAS TEDKAYEIMRELDVDYVLVIFGGLTGYSSDDINKFLWMVRIGGSTDRGEHIKEMDYYTPQ GEFRVDRQGSPVLLNCLMYKMCYYRFGSVYTEAGKPTGYDRVRNAEIGNKDFELDVLEEA YTTEHWLVRIYKVKDLENRGNKLNIRPLLRIIFKRFFGEYTGFTAMCVQHIKSPMANARN KVESIYTGPMDTELVSHMVECDPVGPMMVHTTKLYPTQDATTFHVFGRVISGTLYANQEV RVLGENFSLQDEEDSRFSGAGRLWISEARYKIEVNRVPAGNWVLIEGVDQPIVKTATITE PSGNEEAHIFRPLKFNTSSVIKIAVEPVNPSELPKMLDGLRKINKSYPLVTTKVEESGEH VVLGTGELYLDCIMHDLRKMYSEIDIKVADPVVSFCETVVETSSLKCFAETPNKKNKITM IAEPLEKGLAEDIENEVVQISWPRKRLGEFFQNKYDWDLLAARSIWAFGPDATGPNILVD DTLPSEVDKGLLSSVKDSIVQGFQWGTREGPLCDEPIRNVKFKILDAVIAQEPIHRGGGQ VIPTARRVAYSAFLMATPRLMEPYYFVEV------------------------------- ------------------------------------------------------------ ---------------------------------------------QETFSLFDNRGDDKI YASQLGEVLRAMGQNPTEAEVKKCNDPDCRVSFETFLPIYQTICKNRDTSSVEDFIEGFR VFDKEQNGTISSAELRHLLTSLGERLSDEECEMLLQNQEDGHGNINYEEFVKNILNG-NM FMFNIDNGYLEGLVRGFKGGILKQADYLNLVQCETLEDLKLHLQSTDYGNFLANEASPLA VSVIDDKLKEKLVIEYQHIRNQAVEPLSTFLDYITYSYMIDNIILLITGTLHQRAISELI PKCHPLGSFEQMEAIHIASTPAELYNAVLVDTPLAPYFIDCISEADLDEMNIEIIRNTLY KAYLEDFYSFCKEMGGPTAEVMCEALAFEADRRA-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------VST HGYSQNQILVWKYPSLVQIAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTR STKESKSVLNMFTSIRVLTLIGLYYVLSGQGYRVDFGWFLSETSPYLWCNLGVGLAISLS VVGAAWGIYTTGSSILGAGVKAPRIRTKNLVSIIFCEAVAIYGIIMAIVVGNIMNYAAGF MIFGAGLTVGFSNLACGICVGIVGSGAALADAQNAALFVKILIIEIFGSAIGLFGVIVGI LMTSKAKMGDSMAATRRLAKELEENVDESNILQWTGLIVPENAPYNKGAFRIQIDFPAEY PFKPPKITFKTRIYHPNIDEKGQVCLPIISPENWKPATKTDQVIQSLTALVHDPEPEHPL RGDLAEEFTKDRKKFNRNAEEFTKKYGEKRPSDGASKTFPMQCSALRKNGHVVIKSRPCK IVEMSTSKTGKHGHAKVHLVGIDVFTNRKYEDICPSTHNMDVPNVLRKEYSVIDMDEGFF ELMDEDGEMRSDLSHPATVWKAMDEEKVKEIK---------------------------- -------------------------PTFVCVGDSDNIIVSDGDNHRIQVFDNGHFLYQFG KRGTGKGQFNIPFGVAADLHGNILVVDGGNRRIQIFKHNGDFAGCIELNAPRGIAVTSDG YVVVADRDNHCFKKYKYL-AAGPIAERNQDATVYVGGLDDKVLEATLWELFLQAGPVVNV HMPKDRITQSHQGYGFVEFMGEEDADYAIKIMNMIKLYGKPIRVNKASAHQKNLDVGANI FIGNLDPEVDEKMLYDIFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFEAADAAIESM NGQYLCNRAISISYAFKKDAKGERHGTPAERLLAAQNPLSQADRPHQLFADARAPPQSAP VAPPPPPPSGTTTPPMPPSST-MGVQPPPMPPPGGPPPPA--PPPPVPPGMGPPPGMRPP PP-PPFGGRGMPPNMRGPPP---------------------------------------- ------------------------------------------------------------ ----------------------------------------------------------VP YCIILGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPK SVARIAKLEKAKAKELATKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVVIKKIHAR QIFDSRGNPTVEVDLHTEKGMFRAAVPSGASTGIYEALEMRDKVKGEYHGKGVMNAVNNV NKIIAPALVHDIADQTAMDKIMFDLDGTENKSKLGANAILGVSLAVCKAAAAHKDVPLYR HIADLAGNKDVILPVPCFNVINGGSHAGNKLAMQEFMILPTGAKTFSEAMKMGSEIYHHL KAVIKSKYGQDACNVGDEGGFAPNILSNFEGLDLLVQAIEKAGYTGKIQIGMDVAASEFC KKYDLDFKNPNSNPAEWLSSDQLFGVYQEFVAKYPVVSIEDAFDQDDWDAWSKMNAIQLV GDDLLVTNPKRVQEGIDRKACNCLLLKVNQIG---------------------------- -------------------------------------------------------XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXMNAPPTFECFLLYDGEKKIEIQKDTKVPNAAIFIINKEDHTIG NALTVQLLKDPQVIFAAYKNPHPLEHKVNVRVQTTSEYSPQEAVTNAITDLISEFSLLEE RFKESIREKQSGDEDHRRKWDPEEYERLALERLEAEAGKKEPPIKRETLKPRDYKVDLDS KLGRSQVITKTTPSAQQGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRIERSSLD SVKKRFEMNKKKLEEK-------------------------------------------- --------------------------------------------AKDIKLLLLGAGESGK STIVKQMKIIHEGGFTSEDNKQYKPVVYSNTIQSLVAIIRAMGTLNIAFGDQERESDGKM VLDVIARMEDTEPFSEELLQAMK------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YHS QFLNPSQVVGNMALLPLRTTFKGPAFDIIDEAIHYFKANVFFRNYEIKNESDRTLIYITL YISECLKKLQRCQSKNQGLKEMHTLAISRFYLPGENNFPLNALYNKPSSRNEEESMRMYL QQIRQETGIRVCEKVFDPATDKPSKWWMCFVKRKFMDKSLSGPGQAGPYNYSYIFKYIII GDMGV-KSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVAGQKIKLQIWDTAGQERFRAVT RSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIFLIGNKSDLEAQRDVTYE EAKQFADENGLMFLECSAKTGENVEEAFLDTAKKIYQNIQDGSLDLNAAESGVQHKPITP RPPL--DQNPGKEGCSC----AVCVLGSDAVKGSVFFEQSG-VKVTGEISGLAAGLHGFH VHEFGDNTNGCVSAGPHFNPKGVDHAGPTDAVRHVGDLGNVTADALHIEDKVITLVGPDS IIGRTVVVHADPDDLGKGGHELSKTTGNAGGRLACGVIGICKMVNFTVDEIREIMDKKKN IRNMSVIAHVDHGKSTLTDSLVSKAGIIAGAKAGETRFTDTRKDEQDRCITIKSTAISMY YIMSEKDCCTAFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQA IAERIRPVLFMNKMDLALLTLQLETEDLYQTFQRCVENVNVIIATYGEDGGPMGEIMVDP AKGTVGFGSGLHGWAFTLKQFAELYSSKFKIEESKLMRRLWGDQFYNYVRGFTQYILDPI YKVFNFCMSKEEALGLIEKIGVKLTSEEKDLQDKALLKTVMRKWLPAGEALLQMISIHLP SPHTAQKYRIDMLYEGPSDDEVAVSMKNCDPKGPLMMYVSKMVPTSDKGRFYAFGRVFSG TISTGQKVRIMGPNFTPCKTVQRTILMMGRYIEPIEDVPCGNICGLVGVDQFLVKTGTIS TFDGAHNMKVMKFSVSPVV----------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------RGVRFDIHDVTLHTDAIHRGGGQIIPTTR RVLYACALTAKPCLLEPVYLVEIQCPENAVGGIYGVLNKRRGHVIEQ------------A YLPVNESFGFTADLRAATGGQAFPQCVFDHWQILIVADTRKRKGIKEGIPPLENYLDKLM LPLSLLRTAVNHPMLVELKNGETYNGHLVSCDNWMNINLREVICTSRDGDRFWRMPECYI RGSTIKYLRIPDEVIDMVKEEVVQRGRGRGEMR-GGRGAPGRGGFGGRGGRGGGGGRGGG GGG--------------------------------------------------------- --------------------------AETNVGTHDAPIRCVEYTPEVNVVVTGSWGSTVR LWDPRTPCSAGTFSQPDKVYTLSLTGDKLVV----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------MDFQHRAGGKTGVGGVASASESNRDRRERLRQLALETIDI NKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQANLARRAAKEAKDAPSQPAPE KRSVDIKKFVKIGRPGYKVTKQRDPETQQQSLLFQIDFPEIVEGVIPRHRFMAAYEQKVE PPDKKWQYLLFAAEPYSTIAFKVPSREVDKDSKKFWTHWNKETKQFFLQFAFKHHPSSLP PPPPGGMPPPPRMDDDQECHKLWRIRKTIMQLCHDRGYLVTQDELDQTLDQFKAQFGSKP SERQPSRSDLIILVAHNDDPTDQMFVFFPDDPKVGIKTIKTYCQRMQEENIHRAIIVVQH GMTPTAKQSLVDMAPKYILEQFLEAEL--------------------------------- ------------------------------------------DDKDSVGTVIGIDLGTTY SCVGVFKNGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDAKRLI GREFSDPMVQKDAKHFPFKLVNKNSKPNVQVNVGGSPKDFAPEEISAMVLVKMKETAEAY LGKTVTHAVVTVPAYFNDAQRQATKDAGVIAGLNVMRIINEPTAAAIAYGLDKKEGEKNI LVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKTGKDVRK SNRAVQKLRREVEKAKRGLSAQHQARIEIESFYEGEDFSEALTRAKFEELNMDLFRSTMK PVQKVMEDADL------------------------------------------------- ------------------------------------------------------------ -----------------------------------QILVTFELDVNHILTVSAMDKGTGN EERIVVSSDSRRLSPEEIDAMIVDAERFADEDKLTKERVDARNDLESYSYTLRNQLREQE -----------------------------DSDAEEYKAQKKQLEDIVQPITSKIYGAQPP MEE-------TAEGEDPELEAIKARVREMEEEAEKLKEMQSEVEKQMSIEEKIDADSRSV YVGNVDYGATAEELEAHFHGCGAINRVTILCDKFTGHPKGYAYVEFVDKDSINMANALDE ------------------------------------------------------------ ----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXX-------------------------------------------------- ------------------------------------------------------------ -------------------------------------------------IKEGLMTTIHA YTATQKTVDGPSGKAWRDGRTAAQNIIPASTGAAKAVGKVIPALNGKLTGMAFRVPTPDV SMLE-------------------------------------------------------- -----LLSWYDNEFGYSCRVVDLIKH-----SDDLATAILRRKQRPNRLVVEEAVNEDNS VVSLSQAKMDELQLFRGDTVLLKGKRRKETVCIVLSDDTITNDKIRINRCVRNNLRIRLG DIVSIQACPDVKYGKRVHVLPIDDTVEGITGNLFEVYLKPYFLEAYRPVRKDDIFIVRGG MRAVEFKVIETDPSPYCIVAPDTVIHCEGEPVKREEEEEALNDVGYDDIGGCRKQLAQIK EMVELPLRHPQLFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSK LAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQ RSHVIVMAATNRPNSIDAALRRFGRFDREVDIGIPDATGRLEILRIHTKNMKLAEDVDLE QIAAETHGHVGADLAALCSEAALQQIREKMDLIDLEDESIDAEVLDSLAVTQEDFRWALG KSNPSALRETAVEVPNVSWEDIGGLENVKKELQELVQYPVEHPDKYLKFGMTPSKGVLFY GPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFD ELDSIAKARGGNVGDGGGAADRVINQLLTEMDGMSSKKNVFIIGATNRPDIIDPAILRPG RLDQLIYIPLPDDKSRIQILKANLRKSPIAKDVDLDFMAKMTEGFSGADLTEICQRACKM AIRESIETEIRKERERASNPDDYDAVPEIRRDHFEEAMKFARKSVTDNDVRKYQMFAQTL QQSRGFGG---------------------------------------------------- ---NNVRCWEVQSNGQTIPRAQQTHTGPVLDVAWSDDGTKVFTASCDKTAKMWDLNSNQA VQVAQHDAPIRTVHWVKAPNYTCLMTASWDKSLKFWDARTPNPMMTIQLPERAYCADVLY PMAVVGTAGRGLIIYQLENQPQEFKRIESPLKYQHRCVSIFTDKKTNAPTGFALGSIEGR VAIHYVNPQNPKDN---------------------------------------------- ------------------------------------------------------------ ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMDD SDILTTLKILIIGESGVGKSSLLLRFTDDNFDPEQAATIGVDFKVKTLTVDGNRAKLAIW DTAGQERFRTLTPSYYRGAQGVILVYDVSSRSSFQRLDTWLNELDTFSTKQDIVKMVVGN KIDKENREVSRDDGLKFARKHHTLFIEA-------------------------------- -------------------TKSQKFCRNEYNVTGICNRASCPLANSQYATVREEKGVIYL YSKTIERAAFPARLWEKVKLSRQYEKALKQIDDHLIYWPRFVKHKCKQRF---------- ------------------------------------------------------------ ---------------------------------------LGQLRYTAPERLKKFSIYRYD PDSPGAKPSMQDYEVDLDTCGPMVLDALIKIKNEQDPTLTFRRSCREGICGSCSMNINGL NTLACLCKI-GDANKKMKIYPLPHLFVVKDLVPDMSNFYAQYTWIEPYLKKKDENEENFG KVAHYQSPEDRAKLDGMYECILCACCTTSCPSYWWNSDKYLGPATIMQAYRWVMDSRDDY QKERLDQLRDKWSIYRCHTIMNCVKTCPKGLNPAAAIAELKKMMIGMESHGIPYQDIRPN YTIYINNLNELIKKDELKKSLYAIFSQFGQILDIVALKTLKMRGQAFVIFKDINSATNAL RSMQGFPFYDKPMRIAYAKKDSDLIAKMKGTFVERPKKKRQVEGGKKKKKQGPASIPEQP PHHILFLTNLPEETNEMMLSMLFNQFPGFKEVRLVPGRYDIAFVEFENEVQAGAARDALQ GFKITPTNAMKISFAKKMDRQGRNVIVCDNGTGFVKCGYAGSNFPAHIFPSLVGRPILRS NTKVGDIEVKDLMVGDEASALRSMLEVNYPMENGIVRSWEDMIHLYDYTFGSQKLNISPR ECKLLLTEPPMNPTKNREKMIEVMFEHYQFDGLYIAIQAVLTLYAQGLLTGVVIDSGDGV THICPVYEGFALPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRIMKEQLCYV GYDVEQEQKLALETTVLVESYTLPDGRVIKVGGERFEAPEALFQPHLINQEGVGVAELLF NTIQAADIDTRPEFYKHLVLSGGSTMYPGLPSRLEREIKQLYLERVLKGDREKLSKFKIR IEDPPRRKHMVFMGGAVLADIMKDKEDFWMSRKDYEEKGLRVMAKLGVSMADTVGKPIEC RAAVAWEAKKPLSIETITVAPPKAHEVRIKVLATGVCHTDAYTLDGFDSEGKFPVVLGHE GGGIVESIGEGVTSVAVGDHVVPLYIPQCKECKFCKSPKTNLCSKIRETQGAGVLPDGTS RFTCEGKTLYHFMGCSTFSEYTVVADISVTKVDAAAPLDKVCLLGCGISTGYGAPLNTAK VEPGSTCAVWGLGAVGLATLMGCRKAGATRIIGIDINESKFELASKFGATECVNPKNHDK PIQQVLIGMTDGGLDYTFECVGNVATMRAALESCHKGWGQSVIIGVAPAGTEISTRPFQL VTGRVWKGTAFGGWKSRDSVPKLVDEYMKKELMVDEFVTHSMQLDKINEAFDLMHAGKSM ESYDVIANQPVVIDNGSGVIKAGFAGDQIPKYHFPNYIGRPKHVRVMAGALEGDMFIGPK AEEHRGLLTIKYPMEHGVVKDWNDMERIWQYIYSKDQLQTFAEEHPVLLTEAPLNPRMNR EKAAEIFFETFNVPALFISMQAVLSLYATGRTTGIVLDSGDGVTHTVPIYEGFAMPHSIM RVDIAGRDVTRYLQLLLRKEGHNFHRSAELEIVKTIKERACYLTINPQKEETVETEKTQY TLPDGSTLEIGPARFRAPELMFRPDLIGEECEGIHEVLAYAIQKSDMDLRRTLFSNIVLS GGSTLFKGFGDRLLCEVKKLAPKDIKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKR EYDEDGARAVHRKTFDPTKLSKVVVHPLVLLSVVDHFNRMGKVGNVKRVVGVLLGSNRQG ILDVANSFAVPFDEDDKDRSVWFLDHDYLENMYAMFKKVNAREKIVGWYHTGPKLHPNDI AINELMRRYNPNSVLVIIDAKPKDLGLPTEAYIAVEEVHDDGTPTSKTFEHVSSEIGAEE AEEVGVEHLLRDIKDTTVGTLSQRVTNQLMGIKGLHSQLQDIHRYLESVVAGTLPISHPI LYQLQDIFNLLPDVNLSTFVKSVYVKTNDQMCVVYLASLIRSIVALHNLITNKLVNRDAE KNEGKDPKMGLLFSRLWSLFTNEEHKVIIVGLDNAGKTTILYQFLMNEVVHTSPTIGSNV EEVVWKNIHFLMWDIGGQ------------------------------------------ --------LIFANKQDIKGAMSSAEISQQLNLTSIKDHGWHIQACCALTGEGLYQGLEWI TNHIRR--IPTRRVQISDERQMPSDYSTTPGGTLFSTTPGGTRIIYDRQFLMQCRNSPLA KSPP-NLPKIPGVTSPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------A VLGAAGGIGQPMALLLKLNPNIAQLALYDIVNTPGVAADISHCSTRARVSAYQGSDQLSN CLTGCDVVVIPAGVPRKPGMTRDDLFNTNASIVRDLADACAQFCPEALLCIISNPVNSTV PIASEVYKKRGVYNPKKIFGVSTLDIVRANTFIAEAKGLDVSQVNCPVIGGHSGVTIVPL ISQCTPPVSFPSSEHEKMVHRIQNAGTEVVEAKAGTGSATLSMAYAGARFVNSCLEALNG EEGVVECAYVKSDETEAPYFSTPLLLGKNGIERNLGLGKLLEHEAQLLKKALPELNANIK KGDDFVNTNIDRGKDFNIKTRIITDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFAS TLSHLRRLNSPIGRDGKLARPRQLHNTLWGMICPAETPEGAAVGLVKNLALMAYISVGSQ PSPILEFLEEWSMENLEEIAPSAIADATKIFVNGCWVGIHRDPEQLMSTLKKLRRQMDII VSEVSMI----------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------GLFRSVFYRSYKDQESKKGLDQEELFEKPDRAFV GGMRHAVYDKLDEDGIIAPGTRVSGDDVVIGKTMTLPENEDELAGTATRYTKRDASVFMR RSEYGIIDQVMVTINNEGYKFCKIRVRTIKTPQIGDKFASRHGQKGTCGIRYRQEDM--- ------------------------------------------------------------ -GYHQRGNEVLYNGRTGKKLCSQVFLGPTYYQRLKHMVDDKIHSRARGPVQILNRQPMEG RSRDGGLRFGEMERDCQIAHGAAQFLRERLLEVSDPYRVHVCNI---------------- ------------------------------------------GGFSFENCKRNAALELGL KAPTAYKTGTTIAGIVFKDGVILGADTRATEDTVVADKNCSKIHFIAPNIYCCGAGTAAD TEMTTQMISSQLELHRLNTGRTPRLCTANRLLKQMLFRYQGYISAALVLGGVDVTGPHLY SIYPHGSTDRLPYVTMGSGSLAAMAMFENGYKPDMEKEEGMKLVRDGIAAGIFNDLGSGS NIDLCIITKKVEYLRTYEEANKKGVRQGKYRYKHGTTAITSESIRKI-----MSKVTFKI TLTSDPKLPYKVLSVPEGTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPSQSAGNVFL KHGSELRLIPRDRVG---FTFAAFAYIVALILSAFLIFFVIYHIIAFDELKTDYKNPIDQ CNSLNPLVLPEYGIHIFFNILFIFAYQWGTLLLNLPLIIYHIHRYMNRPVMSSAGLYDPT SIMNADQLNRAQKEGWIKLAFYLLSFFYYLYSMIYVLVSSMGLLTILRKMKQKEKEVRIL MLGLDNAGKTTILKKFNGEDINTISPTLGFNIKTLEHRGFKLNVWDVGGQKSLRSYWRNY FESTDGLIWVVDSADRRRLEDCQRELQALLLEERLAGATLLVFANKQDLPGSLPADEIKE ALDLDNIKTHHWLIQGCSAVTGENLLTGIDWIINDIASRIFTMD---------------- -------------IRMTHNLLLNYGLYRKMEIYRPHKATQEEMTKFHSDDYIKFLRSIRP DNMSEYNKQMQRFNVGEDCPVFDGLYEFCQLSTGGSVAGAVKVNKQATDIAVNWAGGLHH AKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGD-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------LPHAPGVQM QDIPEDNAGDETNPDERISIRASDKRMACDEEFSDSEDEG---------------DQKNF ECNICLDTAKDAVVSMCGHLFCWPCLHQWLETRPHRQVCPVCKAGISKDKVIPLYGRGST SQQDPREKLPPRPAGQRSEPENNQQFPGFGFGFQMSFGIGAFPFGLFATSFNFNDGRPPP PNAGSPQHNEEQFLSKVFLWVAVLFIFWLLIA---------------------------- -------------------------------------------------------RLWDL ETGKQVKSIDAGPVDAWTICFSPDARLLASGSHTGKINLFGVESGKKESQLDTRGKFTFS IAYSPDGRYIACGAIDGII----------------------------------------- ------------------------------------------------------------ -----------------------------ETDDQFDARYISFFNRADIDGWELRKGINDL QAYDLVPEPKIIVSMLKACRRLDDYALAVRVMEAVKEKCGNKVSTIWPYIEGEIKPTLDE LGICTLAEMGYDKPELYTQDVFDMVIRVRGLPWSASQEEVADFLEGCDIIDGKAGVHFTY VRDGRPSGEAYIEMGSEEDVERALQKNKQNMGRRYIEVFRSKRSEMDWVVKRSGPNQDAV IRLRGLPYGCSKEEIAHFFTGLEIVPNGITLLHDHLGRTTGDAYVQFANQDLAEQATHKH KEKIGHRYIEIFKSSLTEIRNNYDSQTGHCVHMRGLPFAANEQDILDFFKPLNPVNVVLH YNNGRAAGEADVDFSTHEEAQQAMTKDRATMKHRYIELFYQDRDKPSQIRTSNITAAKAV ADAVRTSLGPRGMDKMIQAGNGDVTITNDGATILKEMQVLHPAAKMLVELSKAQDIEAGD GTTTVVVIAGA-XDAAQKLLAKGIHPTIISESFQQCASKSAEILESMSTPLELSDRQSLL KSATTSLNSKVVSQYSSILSPLCVDAVMKVIDPITATNVDLRDIRIVRKLGGTVEDTELV EGLVLNQKSAGTGGPNKVEKAKIGLIQFCISPPKTDMENQVVVSDYTQMDRVLREERQYI LNIVKQIKKAGVTVLLIQKSILRDAVSDLALHFLAKMKIMVVKDVEREEIEFICKTLGCK PVASLDHMTPDMLGSAELVEDVQCGNSKVVKITGIANQGRTVSVLVRGSNKLVLEEADRS IHDALCVIRCLVKKKALIAGGGAPEIELALRLAEYSRTLTGMEGYCFKHFGEALEIIPFT LAENAGLNPISTVTELRNKHAHGEKTAGINVRKGAITNILEENVVQPLLVSLSAIDLAAE TVRSILKIDDIVNCVMILLEINNRIIEETLTHKFQNALCGNKPEQVDVTVADFDGVLYHI SNPGGDKSKLRVSISLKFFKDLQEHGADALIQREYGDFITTPEDGYNVSIVFDENIPENH EELVKKAGLLKRNCFASVFEKYFEFQEKHKRAVIHYRDEETMYVDARKDRVTVIFSTVFK DDDDIVIGKVFLQEFKEGRRRYQQAPQVLFSHKEPPLELKGSDAKTGENIGYITFVLFPR HEAKDNTINLIHTLRDYLHYHIKCSKAYIHSRMRAKTSDFLKILNRARPEAKN-EKKTIM LMFCPTCANILVVEEGPKCYRFACNTCPYIFNIDRKISNRKYPKLKEVDDVLGGAAAWEN VDSTEETCPSCGHGRAFFMQIQTRSADEPMTTFYKCCDMSCCHRWRKTKFGPLADQDRIF TNLYGRHDWKLKGAIGRGDWYKTKEILLKGHEWIQKEVVASGLRGRGGAGFPTGMKWSFM NRPDDGRPKYLVVNADEGEPGTCKDREIMRHDPHKLVEGCLVAGRGMGARAAYIYIRGEF YNEASNMQVAINEAYQAGLIGKNACGSGYDFDVYLHRGAGAYICGEETSLIESLEGKAGK PRLKPPFPADVGVFGCPTTVNNVETIAVAPTICRRGGDWFASFGRERNRDVLMDFDALVE AQTALGTAALIVMNKDADMIKCISRLMEFYKHESCGQCTPCREGVNWMYKITERFVSGNA RADEIDMLYEISKQVEGHTICALGDGAAWPVQGLVRHFRPLIEERIQSYNAQ-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------VGALHILGREAHNRAVIRGLNCIPLFVQLLYSQNENIQRVAAGVLCELAADKE GAEVIEQEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPPDFKKRLSVELTSSLFRGD Q---DLQWLIIRDNSSFLLKGSTFSREANNLKSKNSFRYNGLVQRKTIGVEPAADGKGVA LVTKKNWRK--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------EGGPARIPFPLFQDLYKYLA TIDGDISQDHINSVITHLQYDVDKQEGFVQPRNFLSDDCPSLS----------------- ------------KMSDKCFKKCIYKPGTSLDNSEQKCIAMCMDRYMDAWNLVSKSYGMRL QRER---MNRLFGKAKSKEPPPNLTDCISNIDSRGESIDKKIAKLDQELAKYRDQMKKMR DGPSKNMVKQKALRVLKQKRQYENQRDALMQQSFNMEQQNYAIQSLKDTKTTVDAMKVGV KQFKKEYKNVNIDQIEDLQDTLEDMMEDANDIQEVMGRSYGMPDIDDDELEAELDALGDE IGLDEDSSYLDDALNAPSAPTGIPGAESAATSDGVAVDEFGLPRIPAQ------------ --------------------------------------------------FSSGKMVCTG AKSEDEAKLAARKYARIVQKLGFPAKFLEFKIQNMVGSCDVKFPIRLEGLVLTHAQFSSY EPELFPGLIYRM-------------------------------------------IEDDD DDEFGMEMEPEQGARRDVEEFPYEVLTTEQIVQHMVDCIKDVNAIVEIPATTTRILLNHF KWDKEKLMECFYDGDQDKLFLEAHVISPYKKIIEITCEICYFPQPRSMSGLECGHRFCTE CWAGYLTTKIMDEGMGQTIACAAHGCDILVDDATVMNLVTDRKVRLKYQHLITNSFVECN RLLRWCPTPDCGHAAKVSYFDSKPVTCQCGHTFCFGCGENWHDPVRCKWLKKWIKKCDDD SETSNWIAANTKECPKCRATIEKDGGCNHMVCKKCRFDFCWVCLGPWEPHGSSWYNCNRF DEDDAKKARDAQERSRAALQRYLFYCNRYMNHMQSLKFEHKLYAMVKTKMEEMQQHNMSW IEVQFLKKAIDVLCQCRQTLMYTYVFAFYLRKNNQSIIFEENQKDLENVTEQLSEYLERD ITSDILVDIKQKVQDKYRYCESRRNVLLDHVHEGYERELWEYQDMANTEAKLSTTDRIVK TVPFPPSHKLTMSEVFDAKGKPKPDVLKQHFILEGRICEDTALRIINEGVSILRQEKTMI DIEAPVTVCGDIHGQFYDLMKLFEVGGPPSSTRYLFLGDYVDRGYFSITERVYDSCMEAF DCLPLAALMNQQFLCVHGGLSPEIHTLDDIRKLDRFKEPPAFGPMCDLLWSDPLEDFGNE KTTEHFTHNSVRGCSYFYSYAACCDFLQRNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSL ITIFSAPNYLDVYNNKAAILKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVT EMLVSVLNICSDDELMSEDD---------------------------------------- -------------------------------------------------------GFSPR GD-RGGDRGGRGGGGRGGFGGGRGGGRGGRGGMGGGKNVIIEPHRHEGVFIARGKEDALV TLNMVVGESVYGEKRMAVEEGKKLEYRAWNPFRSKLAAAILGGVENIHMKPGCKVLYLGA ASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINVAKKRTNIIPIIEDARHPHKYRMLVG MVDTIFADVAQPDQARIVAINAHHFLKNTGHVVISIKANCVDSTAAPEAVFAEEVNKLRS EKIKPREQLTLEPYERDHAVVVGQYRPPPK-MDPKNLKDFAGRLQKGSKGAGLGLGFLGA AGALVYGLYQSMYTVDGGHRAIIFSRIGGVQDEIYREGLHFRIPWFHYPIIYDIRTRPRK ISSPTGSKDLQMVNISLRVLSRPNSAMLPHLYRNLGMDYDDRVLPSICNEVLKSIVAKFN ASQLITQRQQVSLLVRKELTDRARDFNIILDDVAITELAFGKEYTSAVESKQVAQQEAQR AQFVVERALQERQQKIVQAEGEAQAAILIGQALGANPGYLKLRKLRAAQTISRTVAASKN RVYLNAQTLMLNINEKDFDDACE------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------MDKLKNGCIVCNMGHSNTEIDVNSLRTPDLT WERVRSQVDHVIWPDGKRMILLAEGRLVNLSCSSIPSFVVSITSATQALALIELYNAPEG RYKHDVYLLPKKMDEYVASLHLPSFDAHLTELTDDQAKYLGLNKAGPFKPNYYRY----- ------------------------------------------GCCFVTFFTRKAALEAQN ALHNIKTMPGMQHPIQMKPADSEKRN-EERKLFVGMLSKKCNENDVRMMFAPFGQIEECT VLREQN------------------------------------------------------ ------------------------------------------------------------ -------------------------VSAFFSSLSLCPTELVKCKLQALTKQIIRTEGIQG LFRGLTATLIREMPGYFFFFGGYELCRTALTPKGKTKDDLGPATVL-------------- ----------------------------RTFPATGALFLAYENTKKFLQSMYGDFSGLCD TISSNIFRINSNITSVDRAMKQIGTSRDSKQLRDKIHSTEQSTNFVINDTAKAFKQLSNI SRSDRQQKLQYERLKGDFQDTVQRYNSLQKKAAEKVKATMLDTDLELLHEREDRIRQLEA DVLDINEIFKDLGMLVHEQGETIDTIEENVENGNVEAGNDQLTQAVRYQRKARKKMCILV IILVIIAAIIALVI-----MVNVTKGLLVECDPAMKQFLLHLDDTNALGKKFVIQDLDET HIFISADILPTLQNRIDD---------GKKGDKAPTPQEAIQRLRETEDMLTKKSDFLEK KIEQELTTAKKRAALQALKRKKRYEKQLQQIDGTLSTIEFQREALENASTNTEVLNVMGE AAKALKSAHKNMDVDDVHNLMDDVAEQQEIANEISDAISNPVGFGQDMDEDDLMAELEEL EQEELDRQLLDV-ELPSVPTAEDDEMRELEMWASSMQRFHNRVRQILMASGSTTFTKIVN KWNTA------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------TTLSNYETAT FSSKTEWRVRAISATNLHLRTNHIYVSSDDIKETGYTYILPKNILKKFIIISDLRAQISG YLYGVSPPDNPQVKEIRCIVMPPQWGTHQTVHLPNTLPGHEYLQEMEPLGWIHTQPNELP QLSPQDVTLHAKMMSDNSTWDGEKTVIITCSFTPGSCSLTAYKLTPTGYDWGRQNTDKGN NPKGYLPSHYEKVQMLLSD----------------------------------------- ------------------------NCYTQTRSNLMLTKDTKVICQGLTGKQGTFHSQQAI EYGTNMVGGVSPGKGGQTHLGLPIFNSVAEARSATNADASVIYVPPPFAAKAIIEAIEAE VPLVVCITEGIPQHDMIRVKHALLRQTKTRLIGPNCPGIIKPGECKIGIMPGHIHKKGKI GIVSRSGTLTYEAVHQTTLVGLGQTLCVGIGGDPFNGTNFVDCLEVFLKDPGTEGIVLIG EIGGQAEERAADYLSEHNGDNRKPVASFIAGLTAPPGRRMGHAGAIISGGKGGAQEKIQS LRDAGVHVTMSPAQMGTTILEAMKELGK---ESLKCTLCQERLEDTHFVQCPSVGDHKFC FPCSRDSIKRQGAGSEVYCPSGKKCPLVGSSVPWAFMQGEIATILG-------------- ----------------------------VKRKAIPVKQLHLTQFVVIGPSARTGSVRKAW EKAEISQKWAETTWAKKLVARQKRKELTDYERFKLM------------------------ ----LRVFCSTGRHHNMSEYSRDNTPANELQIYTWMDASLKELTGLVKEVNVDARKKGTY FDFGIVYPDPSRPGHRLREIGTT------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------MDRAHRIGQQKQVRVFRLITENTIEERIIERAEMKLHLDNIVI QQGRLVDPAAHKEVLSMIRHGADQVFASKDSAITDDNIDAILMKGEEKTAELAKKMSTLG ESSLRAFSMDTNEGSVYQFEGEDYREKQKAIGM-NWIEPPKRERKANYAVDAYFREALRV SEPKAPKAPRPPKQPNVQDFQFYPPRLFELLDREIYVYRKTIGSRVAMNTDLGSDAERVR KEEQRKIDEAEPLNDEEGSEKEDLLKGFTNWSKRDFQQFIKANEKYGRDDIESISKEVEG KAPEEVMEYSSVFWERCHELQDIDRIMAQIERGEAKIQRRSSIKAALDAKMARYRAPFHQ LRIQYGTNKGKNYTEEEDRFLVCMLHKCGFDRENVYDELRTAVRQAPQFRFDWFIKSRTA MELQRRCNTLITLIERENMELVEKEKAEKRKEIGTSWADQVEHGDD-DLPPPHEEYDDNN GIKTVIEYKVNDDGKKVRVVKTYRVESRKVSKSIAKRKTWKKFGAASQDPPGPNPANTVE DVYMQFVHTKEADDKDPLERLKVVCRYCKGDHWSKQCPHKDKLEALEEIATIPGKYVPPS LREGGNKRGEAMMSDESATIRVTNLSEDTRESDLQELFEPFGHIQRIYLAKDKATGQSKG FAFINFYNRSDAANAIRGVSGFGYDHLILNVEWAKPSXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX----------------------------------IPFGSSPLKRDITEYVKTGFINL DKPANPSSHEVVAWIKRILRVEKTGHSGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYV CIFRLHSAVENQKKILQCVEQLTGALFQRPPLISAVKRQLRIRTIYESKMLEYDKERNMG IVWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGIQSEKDGLATMHDVLDAQWEFD NHKDETYLRRVIKPLEALLTSHKRIILKDSAVNAVCYGAKIMLPGVLRYEDGIEVNMEIV IVTTKGEAVALAIAQMTTAVMATCDHGIVAKIKRVIMERDTYPRKWGLGPVASRKKSMIK AGTLDKYGKRNEKTPADWANSYKDFRTKKKRKHDTASSEKKKKKKKKQMAEA-WNRKRQP KASQLRSQQAINSAQRHGVPIETSKKFSAGTNKQVGTSKNTAKLDRETEELHHDTIGLDV GRLIQQGRQAKQMTQKDLATKINEKPQVVNDYEAGRAIPNNNVMNKLERALGMKLRGKDK GRPL---MLKPKALTQVLSQANTGGVQSTLLLNNEGALLAFSGYGDKDARVTAAIASNIW TAYERNGQGVFNDDKLRYVMMECEEGKVIITGVANLLLCIYAKESVGFGMLKAKAEALVK YLEEPLTHVAAS------------------------------------------------ ------------------------------------------------------------ ---KGLEQFVNKVAGHPLAQNERCLHMFLLEPVIDKNYVPGKVRLT-------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------TDVHRETTENIRITVMPFYIGEVQQTRVYWWRYSIRL ENLGEETVQLRERHWRIFSLSGTLETVRGRGIIGKEPVFSKSQPAFQYTSHVSLQAPSGH MWGTFKM----------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GECKRGEECPYRHDKPTDPDDPLADQNIKDRFYGINDPV ADKLMKRYGNMPKLESPEDMDVFLMIRRKKMTIFIDAKESTTVLELKKMLQGITKKSPDE MRLFKDNKTLGDYGFTSTTARAQSPATIGLACREFEPLEIAPLSTPPELPDVMKPPETSS SHAQEHLIRYNSVMLRARFDQNKDEDMILAKKLVQEGEVELFQKMHPQPMKFANSPGGTS FGREPVLPDWLLDMWHPLERAQYPEYFARREQRKLEYIERWEKQYGKPSXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAARLFSNIGRLGLGVALVGGVVNTALY NVDGGHRAVIFDRFKGVRDNVTGEGTHFLIPWVQKPIIFDIRTRPRSIPTITGSKDMQNV NITLRILFRPQAGELPNIYNNIGIDYDERVLPSIVNEVLKAVVAQFDAGELITQRELVSQ KVNEDLTMRANSFGLILDDISITHLSFGREFSEAIEMKQVAQQEAERARYLVEKEEQKKK ANVIRAEGDSKAAELIAKSLGDAGDGLIELRRIEASEDITYQLSQSPNVVYLPQGQQTLL SLPMKYIRSNQTINIPDEVELSVKSRNVTVKGPRGTLRRSFKHLAVDIRKISKKQVIVER WFSAQTELAAVRTVCS-------------------------------------------- ------------------------------------------------------------ -----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXKKFAEMKRMISLKDSRIKKPDREKKKKKKRDPQNMSIRELPQASSALFFKYNEQLGPP YHVLIDTNFINFSIKNKLDIVKAMMDCLYAKCIPYITDCVMAELEKLGSKYRIALRIAKD PRFQRLSCMHKGTY---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------DVEQGVCIHTLTRHQEPVYSVAFS PDGKYLASGSFDKCVHIWNVQTGMLVHSYKGTGGIFEVCWNHRGDKVGASASDGSVFVLD LRKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXMAYQTFQQEYMQMPPITRAYTTACVLTTVAAQLDIITPFQLYFNP DLIFGHFQLWRLVTNFLFFGTIGFNFLFNMIFTYRYCRMLEEGSFRGRTADFFFMFLFGG MLMTLVVNLVFLGQAFTIMLVYVWSRRNPYVHMNFFGLLNFQAPYLPWVLLGFSLLLGNS VVVDLMGIAIGHIYFFLEDVFPEQPGGFKLLKTPAFLKWIFDGPADDPNYAPLPPGGFAW G--------------------------------------------------VYGPHEVRG AKSKYDRALINCQFSMATFSTSERKRRPRGDRKSVEMTIHLKQTFEAAIVTSLHPRSQID IFV--------------------------------------------------------- ---------------------------------------------------MAGNYYFVI VGHNDNPVFEMEFSPPNKANEP-KEDHRHLNQFIAHAAMDLIDEQMWQTNNMYLKIVDKF ------------------------------------------------------------ -----------VSQTRFAHTDVQVPDFSAYRRDAPRISRKMFTYVVMGASGATAAYAAKN IAQEFVSTMSASADVLALAKIEVKLSDIPEGKSAVFKWRNKPLFVRHRTEEEITREEAVD PATLRDPEHDSERVQKSEWLVLLGVCTHLGCVPIDGMGEYGGYYCPCHGSHYDASGRIRK GPAPLNLEVPEYTFADEETLVVGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXX---KEFLAKAKEDFTKKWEEPSSNTASLDDFDRIKTL GTGSFGRVMLVQHKASKEYYAMKILDKQKVVKLKQVEHTLNEKKILDAITFPFLVSLEYS FKDNSNLYMILEFVTGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKP ENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVY EMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLKNLLQVDLTKRYGNLKNGVN DIKTHKWFATTDWISIYQKKVEAPFIPKCKGPGDYSNFDDYEEEPLRISSTEKCAKEFAE FMYADTLLILFISICTALLGEGMTWVLVYRTDKYKKLKSEVEKQSKKLEKQKESVGESTE RSVKKKLERQEERLKNNNRDLSLVKMKSMFAIGFAFTSLLSMFNSIFDGRVVARLPFVPI SLIQNLSHRNLSGDDYTDCSFIFLYILCTMAIRQNIQKMLGFAPSRAANKQGGLF----- ------------------------------------------------------------ -----------LVCKEWYRVISDGMLWKKLIERMVRTDLQWKGLAERKLWIQHLFKPKPG EVPKDNKFYRQLYPRIIMDIERIETNWRTGRHTLQRIHCRSETSKGVYCLQYDDTKIISG LRDNTIKIWDRNTLDCVQVLTGHTGSVLCLQYDENIII---------------------- ------------------------------------------------------------ -------TIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACL RILEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLAAALDPRAPSG--------------- -------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXTDGESSCDRNVEIWKIKKLIKSLEAARGNGTSMISLII PPKDQISRVAKMLADELGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVIYCGT IVTDEGKEKKVNIDFEPFRPINTSLYLCDNKFHTEALTALLADDNKFGFIVMDGNGALFG TLSGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAEVAVQLFITNDRP NIAGLVLAGSADFKTELSQSDMFDPRLQAKIIKIVDVSYGGENGFNQAIELASEALANVK FIQEKKLIGRYFDEISQDTGKYCFGVDDSLKALEMGAIETLIVWENLDIMRYVLKNHSAD EEKILFLKPEQEKDKTHFVDKETQVELELVESMPLLEWFANNYKTFGATLEIITDRSQEG AQFVKGFGGIGGILRYQVDFQSLEAYDELEEDFDLDDYXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXX---KPFIPHVPFDLVQCELVFPRAKPAPDEKPLTDALLKRNAELTPS TQEQAAVLNLVTKIQNVLENLVVSPNTFEAAQLEEVRQVGSHKKGTMMAGHNIADIVVIL KTLPTMEAVQSLGNKTLEELKAADPSEMLTMLTNDNGFEISSAEATVKILITTVPRNLKI LDPEMHLDGKLMQGHLSAIRHARWFEENASHSSIKVLIRLLRDLKNRFEGLSPLTAWMVD LLAHYAIMNNPDRQPLAINIAFKRVLKLLAAGFFLPGSAGISDPCEQGNLRVHTCLTLEQ QDQVCFTAQTLLRVL--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------VLYCFSINTGKLERTLTIHEKDVIGIGHH PHQNMVCTYSEDGLLKLWKP---------------TPRLQTFWKYAKVELAPPAEFPAVS QGFNNLIKAQTGKWKQLTTREATLVAVEIGCWFFIGECIGKRGLVGYSIPGAVHYD--XX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXX--------------------------------------- ------------------------------------------------------------ ---------------------------------------------LLLNTTCDLKICDFG LARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDVWSVGCILAEMLSNRPLFP GKHYLDQLNHILGILGSPSVEDLECIINEKARGYLVSLPLKRKVPWAQLAHAKALDLLDK MLTFNPHKRITVEEALAHPYLEQYYDPADEPKAEEPFTFETELDDLPRERLKELIFQETI LLKDK----------------------------------------------PPGDNLYLG IVLTAVVVVTGCFSYYQEAKSSKIMESFKSMVPQFALVLRNSEKLNVHAEELVVGDVIEV KFGDRVPADIRVIQAHGFKVDNSSLTGESEPQIRTVEFTNENPLETRNLAFFSTNAVEGT CRGLVVCTGDRTVMGRIANLASGLEMGETPIAREIAHFIHIITGVAVFLGVTFFVIAFIL GYDWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTI CSDKTGTLTQNRMTVAHMWFDNRIVEADTTEDQSNAQYDRNSPTWMALARICMLCNRAEF KVGQENVPVLKRECNGDASESALLKCVELSIGKVTEYRTAHKKICEIPFNSSNKYQVSIH PDDQRYILVMKGAPERILDRCSTILINGEEKPLTEDWREAFNNSYLELGGLGERVLGFCD YLLPTEQYPANYPFDPDAENFPLTGLRFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVT GDHPITAKAIAKGVGIISEGNETVEDIAARRGIPVSEVNPREAKAIVVHGMDLRDMTPAQ IDEILANHSEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIA GSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLLFILAD VPLPLGTITILCIDLGTDLVPAISLAYEQAESDIMKRQPRDPLHDKLVNHRLIGMAYGQI GMIQASAGFFVYFVILAENGFWPSRLLGIREEWDSKAVNDLQDSYGQEWTYAQRKVLEYT CHTAFFVSIVIVQWADLCICKTRRNSIVHQGMLNHHLTFGLFFETTLAAVLAYTPGLDKG LRMYPLRWTWWIPPMPFSLAIFIYDEVRKYLLRRAPGGWLEIETYYSFKNASRAKKIAVG IGAGAVGLGVALQELELHPPKYPWSHSGMLDSLDHTGIRRGYQVYKQVCAACHSMDYLYY RNLIDVCMTEEEAKAEAEEVLVKDGPNDEGEMYERPGKLSDRFPRPYANDEAAKAANGGA LPPDLSFIVNARHGGEDYVFSLLTGYCDPPEGIELREGLAYNPYFAGGAIGMAQQLYDEG VEYDDGTPASVSQMAKDVCTFLRWSAEPEHDQRKRMGLKTVMIFLIGLSYYVKRFKWSLL KSRKFAWARPDLPSKCTYVLGKIDQSPHAHAKLRPDILPNILGRIGHTPLVQINNITKSL GIECEILAKCEFFNAGGSVKDRIGLRMIEDAEKSGLLKPGDVLIEPTSGNTGIGLALAAA VKGYRCIIVMPEKMSMEKVDILRALGAEIVRTPTSASFDSPESHIGVAKRLLNEIPNAHI LDQYRNPSNPLAHYDGTAEEILVACEDKVDMIVCGAGTGGTITGIARKIKERCPKCIVVG VDPYGSIIAVPEDTTFYEVEGIGYDFVPTVCERTYVTTWMKSEDKKSFLMARRLIREEGL LCGGSSGSSMYCAIEAIKKFNLGAGKRCVVILPDSIRNYMTKFLSDDWMAEREF------ -------LGEYEGERNEREERHGHGKATLPNGDTYEGMYENGKRHGHGVYRFKNGARYIG EWAKNKKHGQGTFIYPDGSKYEGSWVEDQRCG---------------------------- --------------GKREGQGELVHANHKYVGPFREDRPEGRGKYVFDIGCQQYGEYI-- ---------------------FIHNWPRLCFLAMSSSRCVGAIVCKLDMHKKLVRRGYIA MLAIDENFRRRGIGSHLVMKAIRAMVADECDEVV-------------------------- -----------------LIDGLRFHLPPNTKKCLKEEIHKDVLVTGDYELSEAPGQKTTL LVTDSKGHVLYNKDEADKGKFAFTTEEYDMFEACFQTKMTTGMQGADREVFLNMKHGVEA KNYADIAKAEKLKPLEVELKRLEDLSESIVNDFAYMRAREEEMRGTNESTHSRVLYFSIF SMCCLLGLATWQVLYLRRFFKAKKLIE--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------DLLKMFLNLLSTRLKDEPSEFQIDDTFSVPGVGTVVSGTTLKGII RVNDTVLLGPDALGQFMPIAVKSIHRKRMPVREVRGGQTASFALKKSQIRKGMVMVAARL DPKACWEFEGEILILHHPTTISVKYQAMVHVGSVRQTASIITMSQEHIRTGDKATVRCRF IK---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------VEAVAFSPTLNLVATGTLSGSLTLWDAARHTCP-HEAGIVRLQWVED APLVFTASLDGSVRLWDARSG--------------------------------------- REWLGHTEEILDMSLTRDGKNVITASGDSTSRVFS------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------F HPCVRFKRWESERILSFVPPDGNFRLISYHIGAQNMVAIPLYVRHTINFKDGSSGRLDIT VGPKQTMGKSIENVMLEIPFSKSVLNVTLTPTQGKYSFDPVTKIMSWDIGKIDSSKLPNI RGTINLQSGAPPPDSNPNIQVHFTINQMAVSGIKVNRLDMYGEKYKPFKGVKYVTKAGKF QVRT-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------DFSRYNKDRAEAEMAASR RLREAIHHTLQQTDNDLEAQHTNTDYAYRKRMHELKRSIDELNWQKQQTEEEIADQEAEI NRLADAIRAKINPLKLAQTRLENRTYRPNVELCRDNPQYGLCDEVKQLEASKAALEEKLK QAQHALDGLEQNLARINQDLQCKTNSLKLDEQCMSARSKLERNRTLTGITNLKDVLADLI PKEQSRVKEFRSKHGNTKVGEVTVDMMYGGMRGIKGLVTETSVLDPDEGIRFRGYSIPEC QKILPRAPGGEEPLPEGLFWLLLTGNVPTDAQVKAISKEWANRADLPTHVVTMLNNFPSK LHPMAQFSAAITACNSESVFAQAYADGVHKSTYWEHTYEDTMNVIAKLPTIAAIIYRNLY RDGTSVGAIDSEMDWSANFTSMLGYEDPNFTELMRLYLTIHSDHEGGNVSAHTCHLVGSA LSDPYLSFAGGMNGLAGPLHGLANQEVLVWLTKLKYTEQQLKDFIWNTLNAGQVVPGYGH AVLRKTDPRYTCQREFAMKHLPNDKMFKLVSDVYKVVPDILLEQGKAKNPWPNVDAHSGV LLQYYQMTEMNYYTVLFGVSRALGCLSSLIWDRAFGLPIERPKSLSTDKLVEMLKMPFKP PQAEKCQRCEKSVYAAERMEAGGKIWHKMCFRCAKCDMSLKLNNYQQDEGVLYCKNHFQE FILSKNAQIDALFVHRDSPENNADMKFEFTPENMERAQAIIKNYPVGHERAAVIPLLDIA QRQNGWLPIAAMHHVGDVLKMPYMRVYEVATFYTMFNRTPTGKYFVQICTTTPCMLGGIG SGPILQAIKDKLGINAGETTPDKMFTLTEVECLGACVNAPMVQINDDYYEDLTVADMNEI LDDLKAGRKPKAGPR---SGRFASEPAGGLTSLTEPPTGPGFGVRSDL------------ ------------------------------------------------------------ ------------------------------------------AFCHSHNVLHRDLKPQNL LINKNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIF AELANAGRPLFPGNDVEDQLKRIFKLLGTPTEDTWPGL---------------------- ---------------------------------------DGSKFLVHEGPKPGQKYPKQE DCDGWPAEYCEHHPNYEKAKEWMMKNLTADLKVLYLKRQKRGGKGVIKSKKKTTPQGVQL ARAPRGKKKSVTIVTGLKTYEIDLKVASKAFGSKFACGSSVTGEDEIVIQGDVKDDLFDY IPEKWPQIDEDDIDDLGDMKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------------DQFEFD GCDNCDEYLHMKGNRDLVYDCTSSSFDGLISIMSPEDSWAAKWQRLTRMVKGVYAISVTG RLPPGIVRDLKSK----------MPQFPQYLSQEAQDELRQIANAIVAPGKGILAADEST GTIGKRFATIGAENNEENRRQYRQLLFTSLSNYISGVILFHETLYQKTDDGKPFPQVLRE NGIIPGIKVDKGVVPLLGTDGEGTTQGLDGLDERCAQYKKDGCGFAKWRCVLKIQDHTPS YQAMVENANVLARYAMICQKNGLVPIVEPEVLCDGTHDMRTAQKVTEQVLAFQYKALQDH HIFLEGTLLKPNMVTPGQSCPNKVSPQDVAAATTRALRRTVPAAVPGVVFLSGGQSEEDA SIHLDAIN---------------------------------------------------- ------------------YIESLPKVVKRRLKSLKKLQFEMIKIESAFYEQVHELECSYA EKYGPLFERRKDIVNGDVEPTDSDCDWPSDEEEDDEKAVIKDEEKPSGVPQFWLTIFKNV DLLAEMVQDHDEPILEHLHDVKVEFSMGFTLHFHFTPNEFFTNTVLTKTYEMRSQPDEAD PFGFEGPEIVKCTGCKIDWKKGQNVTVKLIKKVQKHQSRGTRRTVTKTVQNDSFFNFFAP PTVTEGEPDEETDALLSADFEIGHFIRERVVPRAVLYFTGEALDEEEEGDDDEED----- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------VMHLDELLP LNMIGIKKVQGGGLEDSKLVAGVAFKKTFSYAGFEMQPKTYEAPRIAMLNIELELKAEKD NAEIRVDNVEEYQSIVDAEWKILYDKLENIHKSGAMVVLSKLPIGDVATQYFADRDMFCA GRVVDEDLKRTMKACGGAIQTSASSLTLGTCEKFIEMQIGCERYNLMTGCPQAKTCTLIL RGGSEQFMEETERSLHDAIMIVRRAVKNDAVVAGGGAIEMELSKYLRDFSRTIPGKEQLL IGAMAKALETIPRQLCDNAGFDATNILNKLRQKHAGTWYGVDILNEDITDNFEACVWEPA IVKINALTAASEAACLILSVDETIKNPKSGDQ-APAGRGRG---KRNNVIPNGHFHKDWQ RWVRTWFNQPARKIRRRNNRAKKAHKIAPRPVAGPLRPVVRCPTFKYNTRIRSGRGFSLE ELKAAGINKKQASCIGISVDFRRRNRSMEGLQQNVQRLKEYKSKLILFPKK--------- --EELKLATQLTGPVMPIRNVYKKEKARVITEEEKNFKAFASLRMARANARLFGIRAKRA KEA--------------------------------------------------------- ------------------------------------------------------------ ----------------------------EPAVLKWIRENIPEWRNCIIVSPDAGGAKRVT SIADKLNVDFALIHKERKKANEVASMVLVGDTKDKVAILVDDMADTCGTVCHAAEKLLDA GATKVYSICTHGIFSGPA------------------------------------------ -------------------LTCRFYEQHFPEKEDVVMCNVRSIAEMGAYVDLLEYKDIEG MILLSELSRRRIRSINKLIRVGRSECVVVIRVDKDKGYIDLSKRRVSPEDVAKCEDKFAK AKCVNSILRHVAELLDYETDEQLEELYQKTAWHFDRKYKKVGASYDAFKHVVTNPEVLDE CELDERTKKELLSNIKRRMTPQAVKIRSDIEVACYSYEGVDAVKNALRAGLNMSTEDMPI KINLIAPPIYVVKTQTLERQEGMARGQQKIQSQQKNAEKLAKQKHDQKKAAAAGLTYVCT VCKSQMPDPKTYKQHFENKHPKSPLPDQLKDV---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------CHKPITG RCITAMYKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCHPCFVKLF-------------- -----------------DGTYCFRLNRDRVYYISELLMKRAGNIARDNLLSFGTCFGKFT KTNKFRLHITALDYLAPYAKFKIWVKPNMEQQFLYGHHIMKSGLGRITENTGQYQGVIVY SMNDLPLGFGVTAKTTQECRHTDPMTIVAFHQADIGEYIRNEEALSGDRKLFVGGNWKMN GNKASIDGIIKFLNEGNPNTDVVVAPSSVYMDYVRSKLIGVAAQNCYKCEKGAFTGDISP AMIKDIGCEWAILGHSERRHVFGESDQLIGEKVAHALAAGIKLIPCIGEKLEEREAGKTN EVIFHQLKFKDWTNVVIAYEPVWAIGTGKTASPDQAQAVHADLRKWMTEHVSADVAKSVR ILYGGSVTADNCRELAAKPDIDGFLVGGASLKPDFVKIINAREREGLLDPAWEKQQRKTF TAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGEQLPKPDRGKMRFHKIANVNKAL QFIESKGVKLVSIGAEEIVDGNVKMTLGMIWTIIVQNFHMSWKDGLAFCALIHRHRPELI DYHKLSKDNPLENLNTAFDIAEKYLDIPRMLDAEDMVNSVKPDERSVMAYVSSYYHAFSG AQQAETAANRICKVLKVNQENERLMEEYERMASDLLEWIRRTTPWLENRTTDNTLPGTQS KLEEFRDYRRQHKPPKLEEKAKLETTFNTLQTRLRLSNRPAYMPTEGKMVSDIANAWKGL ERAEKGFEEWLLSELQRLERLDHLAQKFRHKCEIHEEWSYGKEDMLQAQDFKKCRLNELK ALKKKHEAFESDLAAHQDRVEQIAAIAQELNALDYHDSPAVNARCQRICDQWDLLGTLTQ QRRNALEEAERILERIDQLHLEFAKRAAPFNNWMDGAKEDLVDMFIVHTCEEIQGLIDAH EQFKMTLGEAEKEYRSIMSLVEEVNRISQQYGITGGADNPYTTLSAQDIAHKWTDVKMLV PKRDSTLQQEMIRQQNNERLRRQFAQKANMVGQWIERHLDAVASVGIQKGSLEDHLNKLK GIEKEVLGFKPNIDELERYNQEVQEAMIFENRHTPYTMETLRVGWEQLLTSVARNINEVE NQILTRDSKGITNEQMDEFRKSFFHFDKARSRRLEPKEFKACLVSLGYNIRDDRQGEADF QRIMSIVDPNNTGHVSFDAFLDFMTRETTDTDTAEQVMQSFRILAGDKPFITADILRREL PPDQAEYCIQRMAPYTGRDGMAGALDYTSFSTALYGESDLNKLGIDALDLKDKRVLIRVD FNVPLKGTEITNTQRIDAALPTVKYALDKGAKSVVLMSHLGRPDGKPQEKFSLKPVADCL KTKLGKDITFLKDCVGAEVEAACANPAKGSVILLENLRFHIEEEGKGTDAEGKKIKADPA KVEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGCQLPQKAAGFLLKKELTYFAKALETPV PPFLAILGGAKVKDKIQLIENMLDKVNEMIIGGGMAYTFLKVLNGMSIGTSLYDEDGAKI VQKLMDKAKANNVQIHLPVDFVTADKFAEDATVGKATRESGIPDGWMGLDSGPETCAKFA EVVGRAKTIVWNGPCGVFEFENFAHGTKSVMDAVVHATQQGTVSIIGGGDTATCCAKWGT EDKVSHVSTGGGASLELLEGKTLPGVAALSPAXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXX------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------QVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDQACAGLNGMQLG DKKLIVQRASVGAKNAQQQPVQIQVPGLNATQIPTEILCLMNMVSPDELEDEEEFDDIMD DVREECGRYGAVRSMEIPRPIKGVEVPGCGKIFVEFVSIIDCQKAQQALTGRKFSDRVVV TSYYEPDKYHRREFFIPLFDRVLVERLAAETKTKGGVLLPEKAQGKVLEATVVSVGPGAR SNDGQMIPTSVKSGDKVLLPEYGGTKLKFDDQEYFLFRDSDILGK--RLKGQIPDIRTTL DIVKHMQSKRDEMITQFQLSDHLFVKAKVPPTEKVCLWLGANVMLEYELDEAQSLLTKNA ATSSLEQVDNDLGFLRDQTTTTEVNMARVYNWDVKKRQ---------------------- -----------------------------------------------------AIGSRNL LKSVSKQREAQQQQLQALIAEKKMQLERLRVQQESLLKGEQEQNDFIEQFILQKRSRSRS RDKDSRKRSRSRERDREDLNPEERDARTVFCMQLSARIRPRDLEEFFSSVGKVKDVRIIT DNKTRRSKGIAYIEFQDLDSVPLAMGLTGQRLLGVPIIVQASQAEKNRLAGNSGPMRLYV GSLHFNITEDMLRGIFEPFGKIDQVDLVMDN--GRSKGFGFVTFHNAEDAKKALEQLNGF ELAGRPMKVGHVTERTADSSLLDSDEMDRAGVDLGATGRLQLMAKLAEGTGFEIPKHAAN ALNLNPSNVTPPIATQCFMLSNMFDPINSSPSWEVEIRDDVIEECNKHGGVLHIYVDKAS PQGNVYIKCPSIAAAVASVQALHGRWFAGKMITAAYVPLANYHALFPDATRTVQLLIPS- DERDDEVSPIPPLPTKKRVRRGAVSAEVYTEEDAASYVKKVVPKDYKTMAALSKSISKNV LFSHLDDNERSDIFDAMFPVHRHAGETIIQQGDEGDNFYVIDVGEVDIYVNNDWVSTIGD GGSFGELALIYGTPRAATVKAKTDIKLWGIDRDSYRRILMGSTIRKRKMYEEFLSKVSIL ENLDKWERLTVADSLEPVQFEDGQEIVRQGDQGDDFFIITEGTASVLQRRSENEDPVEVG KLGTSDYFGEIALILDRPRAATVISRGPLKCIKLDRARFERVMGPCSDILKRNIAQYNSF VSLSVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSQRNEL VDKAEDVADQVLRHGKHILPHIARLCLISTFLEDGIRMWFQWHEQRDYINATWGCGWVLA VLFVLINLVGQLVGCVMVLSRKYVNVACGILFGIIALQTVAYSILWDIKFLMRNLALAGG VILLLAESKAEGKSLFAGLPSLGENNHRTYMQLSGRILLVLMFLTLLRFELSPFQLIQNL IGTALIVLIAVGYKTKLASLTLVLWLMVLNMYFNAWWNIPDYKPMRDFLKYDFFQTLSVV GGLLLVVALGPGGYSMDEHKKQW-QKVTMIPGDGVGAELMQSVKDVFKAAGVPVEFEEIW ASDNRICLKGIISTPLSTLNMQIRKELDLFANVVKIRSLPGFKTRHNNLDFVIIREQTEG EYSALEHESVPGVVECLKIITRSNSQRIAKFAFDYATKHGRQKVTAVHKANIMKLGDGLF LETCREVADLYPKIKFESMIIDNCCMQLVSNPYQFDVMVMPNLYGNIVDNLAAGLVGGAG VVPGESYSQDVAVFEPGARHSYAGMAGRDVANPTGMLLCASSMLKHMHLEFHGQLIQDAV EKVIKTGKVRTPDMGGYGTRTDFTYAVINNVSEEYGRFLDRSTRVIERALSEQIDIFTDY TGVEGDEGLTEGEKLKLNRFFFDERWSKHRTVTCIDWSIQHPELLVASYNQNEESPNEPD GVALIWNLKYKKGTPEYVFHCQSAVMSTCFAKFHPNLVVGGTYSGQIVLWDNRANKRTPV QRTPLSAAAHTHPVYCVAVVGTQNAHNLISVSTDGKMCSWSLDMLS-------------- ---------------------------------------MFEGHQGPVTGIDCHAVPGAI DFSQYFISSSFDWTVKLWNIKEQRPMYSFEDNSDYVYDARWSPVHPALFATVDGNGRLDL WNLNNDTEVPTAS--NIALNRCRWHQSGHSIAVGDDVGKISIYDVGEPLAMPKNDEWNRF VHTLQELKNQQAEQEDD-LSEQLTQAAKIVENQLDAEIERLDKLDEDDYEVIRQKRLIAL KKAQTQKHEWLHMGHGKYEELAEEKHFFEVCKKSKNVVCHFYRDSAFRCKIVDKHLAILA PKHIECRFVKINAEKCPFLTQRLRIKVIPTIALVKDEKTGDYIVGFDDLGGHDEFTTEML EWRIAQNQVISYSGDLSTPPVDG------------------------------------- ---------------------------PKTPCVLGFEGSGVVAALGDGVTDPPVGTRVMC CSGLWREYAIEVFPIPDRMTFEEAAAIPVNYLTAYFMLFDFGNLRKNKSVLVHMAAGGVG IAAIQLCKTVPGVTVFGTASAKHDIIREEGCTHPIDYRTQDYVTEIRKIKEDGVDIVLDP LSGEDSQKGFNLLRPMGKIVHFGVANAVKGPNRSLIQFAKTWWSTKSFSPLSLMSMNKAI CGFHLGYMTVMQEILELYDQDKIKPRIDSVWAFEDYAKAMAQMHERRNIGKVIMSTEKMS RK-TPSDFLKQIIGRPVVVKLNSGVDYRGVLACLDGYMNIALEQTEEYVNGQLKNKYGDV FIRGNNVLYISTQKRRIMAKEQAALLLQRQLAELSKHPVEGFSAGLIDDDDIYKWEVLII GPPDTYYEGGFFKAHLTFPRDYPHKPPKMKFKTDIWHPNIDAQGDVCISILHEPGEDKYG YERPEERWLPIHTVETILVSVISMLADPNDESPANIDAAKEWRERRDEFKKKVARCVRKS QECTVRVAQPVMRQTLLEFGSYVGECMPKYVQKVQVTAFDELEILIHPDGVVPVLSFLND HTNAQFRNVADICGVDVPTRENRFEIVYNILSLRFNTRIRVRTYANELTPVQSCTSIFPA ADWYEREVWDMYGVFFANHPDLRRILTDYGFEGHPFRKDFPLSGYVEVRYDDEVKRVVAE PVELAQEFRRFDYSSPWEMFPNYREKLNPFAQVDYRAKIWSCNMCYQRNPFPPQYAAISE QHQPAELIPQFSTIEYTCTRRPCNPPVFLILLDTCMDEEDLQAVKESLQMSLSLLPPNAL VGLITYGKMVQVHELGCEGCAKSYVFRGTKDLTAKQIQDMLGIGRGPAQLPSNRFLQPLH KCDMALTDLLSELQRDPWPVAQGKRPLRSTGVALSIAVGLLECTYPNTGARVMMFCGGPC TQGPGMVVDDELKHPIRSHHDIEKDNCKFMKKAIKHYENLSNRAATNGHVVDIYSCALDQ TGLHEMKYVSNLTGGHMVMGDSFNTSLFKQTFQRVFSKDMKNEFKMAFGAQVDVKTSREL KVQGCIGSCV-------------------------------------------------- ------------------------------------------------------------ -------------------------------SFRFSEQFSLYPQFMFHLRRSQFLQVFNN SPDETSYYRHMLSVEDLTQSLIMIQPILYSYSFNGPPEPVLLDTSSIQVDRI-------- ------------------------------------------------------------ -----------------------------------------------MSNLTQEEQMKLL QDLEIEMMADMYNRMSSACQKKCVPPRYKDEELSKGEGVCIDRCVAKYIDIHDRIGKKLT SMSMQDEETMKKLQS--------------------------------------------- ------------------------------------------------------------ ---------------------------------VPYVETSAKTRANVDKVFFDLMREIRS RKIDEKSRKKKCTIL--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----KLFIRVPNGLKTMCDCISAYLREQGKALVADEEMNKNAITFVQSLLDLKDRFDHFL HESFNDDKLFKQMISSDFEYFINLNAKSPEYLSLFIDDKLKKGVKGMSEQEIENVLDKSM VLFRFLQEKDVFERYYKQHLAKRLLLNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFKD MTVSNTTMEEFKTHTQQRTNLEGVDLFVRVLTTGFWPTQSAKPKCNIPTAPQRAFEAFRR FYLGKHSGRQLTLQPQLGSADLNATFYGAKKDEGEAKGVGRKHIIQVSTYQMVILMLFNS QDKLTYEEIRNETDIPEKDLMRAIQSLALGKITQRILAKEPKTKEIEPHHNFTVNDQFTS KLYRVKIQTVAAKGESEPERKETRSKVDEDRKHEIEAAIVRIMKARKEMQHNVLVAEVTE QLKARFLPSPVIIKKRIEGLIEREYLARKPDDRKVYTYVADKINVFPSRMNMAIMKARLK GAQKGHSLLKKKADALTLRFRMILKKIIETKILMGEVMKEASFSLAEAKFTMGDFNHLVI QNVNKAQMKVRSKFDNVAGVNLPIFEAFADGSDSYELTGLARGGQQIDKLKKNYAKAIEL LVELASLQTSFVTLDEVIKITNRRVNAIEYVIIPRIERTLAYIITELDEREREEFYRLKK VQGKKKAIQ--------------PIRVLITGAAGQIAYSLLFSVAKGDVFGTDQPIILHL LDIEAMMGVLNGVVMELTDCALPLLHNVIATSDVNVAFKDIDVALMVGAMPRREGMERKD LLRANVKIFKAQGQALDQHSXKSVKVLVVGNPANTNSYICSKYAPSIPTENFSCLTRLDQ NRAAAQVAERQDVTNVIIWGNHSSTQFPDVNH---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------PQVYYFGPCGRYNALV LELLGPSLEDLFDLCDRKFSLRTVLMIAVQLLTRIEYVHTKHLIYRDIKPENFLIGRQSN KKQHIIHIIDFGLAKEYIDPETHKHIPYREHKSLTGTARYMSI----------------- ------------------------------------------------------------ ------YDYLRKLLLDLMSKKGWECDWEFDWTGRQL------------------------ ------------------------------------NLDPLTETYGLPFYMQYLAHWPEY FKVAESPSGHIMGYIMGKAEGPNENWHGHVTALTVAPEYRRLGLAAKLMNILEDISEKKS CYFVDLFVRVSNKVAVDMYHHLGYSVYRTVLEYYSGDHDEDAYDMRKALSRDVEKKSVIP LPNPVRPEDLEQQLDCALDLMRRLPPQQIEKNLTDLIDLVPSLCEDLLSSVDQPLKIARD KSVGKDYLLCDYNRDGDSYRSPWSNTYDPAMEDGAMPSERLRKLEIDANAAFDQYRELYF EGGVSSVYLWDLEHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRSAHYKLTST AMLWLQTNKAGSGTMNLGGSLTRQVEQDNPVTEANPHIVNIGRMVEDMENKIRNVLNQIY FGKTKDIVNGLRSTTSEQMADLTKDLAEALRNRSQDDDDLDEVPEPFDAENE-ENIDVLP EDRRVDPQKRITTPYLTKYERARVLGTRALQIAMCAPVMVELEGETDPLVIASKELKARK IPMIIRRYLPDGSYEDWGIDELIMTERAPTLKERAMAPAGDGAFTMGRGLVAGASLVGLG SLCFYGLGLSNEVGAIDRASLWPDIVRQRVRDTYMYFGGSLGFTAVCRSPTMMNLMMRNS WMALIGTMVAMIGSGMVARSIPYKEGSKQLAWMVHSSIVGAVIAPMTLLGGALVLRAACY TAGVVGGLSTLAICAPSDKFLNMGGPLAMGLGVVFISSISTMFLPPTTALGAGLYSIALY GGLVLFSGFLLYDTQKIIKRAETHPTYTTVPYDPINNCISIYLDTINIFIRILTILAGGG NRRR-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------LSIQVCDEPLHSIRVQDQGRLIACGSKSGTTTL LELSDGLATLQRNEKTLVTAMFERETRREKILESRHREMK--------WDELVSRIGPIA NPLASRKLTKRIYKCIKKALRKGVREVQKFIRKGERGLVIFAGDTNPVEVICHLPCVCEE NEMPYCYTPSKEDLGAACGSKRPTCMVMIKRGEDYEELYDQCQEELKSLPLPIMPVENLE EEGLAKNPNLQLAQWKFLLGTDTHKNDAKIKNDIMEAVQADDMSSFYEEVCRDLGWTMDG TLLANMKAKNEAEFKKIDESIEDAEKNLGETEIREFMLKKAEYYSKIGDKEAALTQFRKT MEKTVTLGYRLDIVFHLIRIGLFYMDHDLIKRNLEKAQTLIDEGGDWDRRNRLKVYKGMY HMGIRDFKTAANLFLDTIATFTSYELMDYKSFVTYTVFCGMIALDRPTLREKVVRGSEIL EVLHGLPDVREYLFSMYDCRYEQFFKKLAQVEHFMKYDRLFAPHFRYYAREMRIMAYSQL LESYRSLTLEYMANSFGVTTDFIDQELSRFIAAGRLHCKIDKVGGIVETNRPDSKNYQYQ STIKQGDLLLNRIQKLSRVINV-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------IAPPDYFKITSKDAMMY TTGLGGMVGLGCISPNADFTTMVSIFGLAGIVGYHTVWGVKPALHSPLMSVTNAISGITA VGGMLLMGGGYTPSSTAQALAAAAAFISSINIGGGFLVTKRMLDMFKRPDDPPEYNYLYG VPAAVFLGGYFAATQGNYPDIHQMAYLAASLCCVGALTGLSSQGTSRLGNTLGMIGVSSG IAATLGLLKPTPEVMTQMALCMAGGGALGMTGAKVIEVTDLPQMVALFHSLVGAAAVLTC ISNYMIEFPHFATDPAAGVVKTALFLGTYIGGVTFTGSLMAFGKLQGLLKSDALLLPGRH MLNAGLLAANIGAMGAYMTTADAFGMSMLGTTTALSSVMGVTLTMAIGGADMPVVITVLN SYSGWALCAEGFMMNNNLMTIVGALIGSSGAILSYIMCVGMNRSLPNVILGGYGTTSYAG GKAMEITGTATEIDVTGTVDLITEAQDIMIVPGYGLCVAKAQYPIAELVDLLRKKGKNVR FGIHPVAGRMPGQLNVLLAEAGVPYDIVHEMDEINDDMPHTDLTLVIGANDTVNSAAEED PNSIIAGMPVIRVWLSNQVIVMKRTLGVGYAAVDNPIFFKENTNMLLGDAKKTCDALLTS TRMTRPEVIPGCPPGLEYLTQVDQIVVKQIIEMLELFTGWETQNKYRLLNSMGQQVYYAA EESDLCMRQCCGPARGFVIHITDNAGQEIMRVTREFKCCAGCCWCANCAFELTVEAPPGQ PIGKVRQESWKPSFSIRDLVAYIEGPCCVCNAPCC-GDVEFPVLGTQIGKIAKQWTGALS EYFTDADTFSVSFPQDMDVRMKATFLGAVFLI----------SADPELQQFLMLEQQKAQ LQSSIHRLTDTCWDKCIDKPRDKLDYKTEQCLSNCVERFIDTTLQITNRFQQMLQRSMXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXSKKLTDITVENCEVCVKFIQKFDDTIDKIENALMAAC RKAKKDDNRFCYYIGGTDDSATSIINEVTKPLSYHLPAEKICKKLYKKDEQICDLKYDKE LDLTNVDLKKLKVKDLKKILSDWEEQCRGCTEKNDFVARVEELLPQHAPQAAXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXMPKVISRSVVCTDTKDQEEYQGEKPLYVYYCLCGQISLILDCPIE KLPMRRVDNARVIDSNKHAHKLTCEPDETVHIKRPNGIERQYRQKCKKCGLLLYYRHKNI VTFIVDGALKRSMEIQSDIYSQISEPKKVMVTKHTKNM---------------------- -----------------------------------------------------AAHQQRN GYADMAFTFASGGGANVKQVDVPSFSGSFGILPDHVPLLAVLKPGVVTVQEQDGASKKFF VSSGSITINDDSSVQILAEEAVPVESLDPQAIREGLSKATQDVTSDTAKAEAQIALECFE ALDKAI-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------VTSEADVKSAIAAQN KFGGLNAAINCAGIGVAHVTYNRNKDRVHDLESFARVLTVNTVGTFNVIRLAAQAMNKNE PNKDGQRGVIVNTASVAAFDGQRGQAAYSASKGAIVGMTLPIARDLAVCGIRVNTVAPGL FDTPLLASLPEKVRTYLASTIPFPSRLGDPDEYAHTVQYLVENPKVNGEVIRVDGALRTR DFHFRVHDRNTDVKSQISSDYPVVDHTYDAVVVGAGGAGLRAAFGLAKEGFKTACVTKLF PTRSHTVAAQGGINAALGNAEHDKWEWHFYDTVKGSDWLGDQDAIQYMCEQAPAAVIELE NFGMPFSRTDQGGIYQRAFGGQSLDFGRGGQAHRACCVADRTGHSMLHTLYGRSLHYETD YFIEYFALDLMMQDGKCVGCVALSLEDGNIHRFHAKNTVLATGGYGRAYFSCTGAHTCTG DGTALVSRAGLPNQDMEFVQFHPTGIYGAGCLITEGCRGEGGYLMNSEGERFMERYAPTA KDLASRDVVSRSMTIEIREGRGVGPEKDHCYLQLSHLPPEQLAQRLPGISETARIFAGVD VTRDPIPVLPTVHYNMGGVPTNYQGQVITYNGNDKIVPGLWAAGEAASVSVHGANRLGAN SLLDLVVFGRACALNIAATDKPGDKLPELDQNAGEETVANIDKLRHSNGQTSTADLRLRM QKAMQNHAAVFRDSKSLKEGVQKLDTLATEMDLKVTDKGMIWNSDLVETLELQNLMLNSV QTMYSAENRKESRGAHSHEDFPDRKDEFDYAKDLAGQEELPFEKHWRKHSLSYCD-AKGK VKLDYRPVIDKVLDKTKIDTIPPKLRVYMTALTQEEILSNTKTVVQGLDTLKNEHNQILN SLLNSMKTIKKADTNLVEEKTNILKKSVEMIELGLGEAQVMMALANHLQYVEAEKQKLRA QVRRLCQENAWLRDELANTQQKLQISEQKVATLEEEKKHLEFMNEMKKYDMEDSLGFPED DDESQE-------------------------REENKGKHKDSVPYGEYG--GWHKAAKVD SPTVTTTLKNLGALYRRQGKFEAAETLEECAMRSRK------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------QRHGFNGPVIGPKPTEKNVREFTEEQLKAGQGQAGWNKGA TQGAG-VRHCADIRADDMDKAGQAILGGQSGNKGATQAGMGAG-VRHCADIRADDMDKAG AGILGGQSGWNKGASQSGMAMGGTRHAADIRADDLDAAGQSVLGGQTGWNQGASQAGMAM GATRHAADIRADEMDAGQSVIGLQAGSNKGASQAGMAIGATRHAADIRADAAVGANVIGL QMGSNKGASQSGMAMGATRHVADMNVGPMKSQAVIHLQMGTNEGATQSGMSMGGRRDI-P DVHSFGIEPITCHAWNGDRSQLAIPNNHEVHIYKHEWQRTDTLQGHVQRVNGIDWAPSSN RIVTCGSDRNAYVWPTLVILRINRAATCVKWSPLENKFAVGSGARLISVCYFEQDNDWWV SKHIKKPLRSTVTSLDWHPNNVLIAAGSTDFKARVFSAYIKEVDEKPASTPWGKKMTFGN LMQEFSIGGGWVHSVSFSSTGVKLAWVGHDSSVNVVDASVKTSYLPYVTCCWVSHNSILV AGHDCCPMLFSYEGSSLTFVAKLDAKKVTAMAHFKSMDYHGQNLNTLHQNTITQVSIYGG SKESAAKFSTSGIDGK-------KEIEGYVGFANLPNQVYRKAVKRGFEFTLMVVGESGL GKSTLINSMFLADLYSSEHPGPSHRIKKTLSVETTQVLLKENGVQLRLTVVDTPGFGDAV DNSNCWQPITNFIEAKYDEFLNAESRVNRKTNPDHRVHCCLYFISPNGHGLKALDVEFMK RLHDKVNIIPLISKADTLTPDECREFKKTILNEIAQHNIKIYEFDDEEENKHQKKLKDRV PFAVVGSNTVVDSQGRKVRGRIYPWGVVEVENLEHNDFIALRNMLIRTHMQDLKDVTNNV HYENFRYNKLSAVTKSPLLQMEDERKEHMTKMKKMEAEMEQVFEMKVKEKKQKLKDSEHD LQRRAEQMKKSLEQQAREVEEKRMSFEKERAMWEEQQQMARRYDTRTTIFSPEGRLYQVE YAMEAIGHAGTCLGILAKDGVILAAEKRNTNKLLDEVSYSEKIYKLNDDMACSVAGITSD ANVLTNELRLCAQRYLLQYQEPMPCEQLVSALCDVKQAYTQFGGKRPFGVSLLYMGWDKH YGFQLYQSDPSGNYGGWKATCIGNNSAAAVAMLKQEYKENEMKMDDALQLAIKVFGKTLD TNKLTAEKIEISTLTRENGNTRIQILEDKKVDALIKEYEESEAKIEADKKEELNEAWERL KSLSLKRQEKLYGAHEIQHFNRDADETLTWISEKDVVLSNEDFGRDLASVQTLQRKHDGV ERDLAALEEKVKALGTEADRLTETHPEMNDDIRNKQSEIEDSWQRLRNKAAERKARLDDS YNLHRFLSDYRDLISWIQDMKNIISADELAKDVAGAEAFLERHQEHKGEIDAREDSFRNT ADAGQQLLESDHYAVDEVKEKLMTLANEKTSLLELWEERRILYEQCMDLQLFYRDTEQAD AWMSKQEAFLANDDLGDSLDSVEALIKKHEDFEKSLAAQEEKIKALDDFASKLIENEHYA ADDVAARRDQLLQRRNALYEKSRERRFKLEESYKFQMFERDCDETKIWINEKQKAASDEG YLDPTNLQGKVQKHQNFEAELQANKPRIEAVHATGQELIEAEHYASDTIKERLDEIQQLW QKLQEQSERKGLKLKEASEEQQFNRNVEDVEVWLAEIEGQLMSEDYGKDLTSVQNLQKKH ALMEADVAQRQDRLDHIVASSENFLQSGHFDSDNIKKKEAVVVDRYKVLVEPLKQRKTKL IDALRLQQLYRDIEDEEDWMREKEPIAASTNRGRDLIGVQNLMKKHQALQAELAGHDSRI HQVVEQGDEMIRDGHFAAEDIKKKTEELHDRWNQLNNKSEQRTQDLADSLQAQQYFADAN EAESWMKEKEPLVGNTDYGKDEDSAEALLKKHEALMSDIESYRTVIDSLVEQAQLCKQQE APVVDDLGKECVVALYDYQEKSPREVSMKKGDVLTLLNSANKDWWKVEVNDRQGFVPAAY VKKIDSSLTASQSNLADEFTISVRQNQISTQYENLLDMGRQRANKLKESNKAYQLVREAG ELAQWINDKETVVLADEVGEDLEQVEVIQRKFDDFQKDLKANEARLVELNTIAERLTAMG QTEAAEKIKIQIEDLNTRWAALQQVTQERAQTLGSAHEVQRYHRDADETKDWIEEKDNGL NMEDFGHDLATVQRLQRKHEGLVRDLAALGEKVEELNDTSNRLMQTHPDQAQSIHEHQKE INERWNDLTAKADQRKAKLLDSYDFQRFLSDFRDLMSWINSMMALVSSDELAKDVTGAEA LLERHQ------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------KHQKHQAFEAELAANADRIQAVVQMGKKLID NQSCSGTEGAVEDRINKLAQEWESLTTKSSEKSEKLQEANRQRMYTAAVKDLEFWLGEVE HMLESEDYGKDLATVQNLVKKHQLLEADVRAHEDRVRDLNEQADQFIDSGVLDTESIKEK KQSINERYERVTTLAAHHLARLNEANTLHQFLRDIDDEEAWIKEKKLLVGSDDFGRDLTG VQNLRKKHKRLEAELSSHEPAIQEVQDTGEKLMAESNLMNEDIQRRMQQLADSWDELKQM AGNRGQKLDESLTYQQFAANVEEEEAWITEKQHLLSGDDYGDTLAAVQGLLKKHDAFDTD CQVHKDRCSEMNKDGQRLIDEGNHNHELIRQRCEQLNNKLSSLEEAALLRKERLIDNSAF LQFIWKTDVVESWIADKETQIRSDDYGRDLSSVQTLLTKQETFDAGLQAFEKEGIQTITA LKDQLIAANHAQSNAIERRYNDVITRWQKLLGDSDARKQRLLRLQEQYRQVEDLYLTFAK KASAFNSWFENAEEDLTDPVRCNSVEEIKALREAHEQFKASLSAAETDFNQLAALDKQIK SFNVGPNPYTWFTMEALDDTWRNLQKIIRERDDELAREQQRQEENDIMRKQFAQAANAFH GWLTDTRAAMMEGSGSLENQLEATKRKSAEVRAQRSQLKQIEDLGAAMEERLILDNRYTE HSTVGLAQQWDQLDQLGMRMQHNLEQQIEARNKSGVSEEALREFSMMFKHFDKDKTGRLD THDFKSCLRALGYDLPMVEEGEKDPEFEAILDIVDPNRDGFISLQEYMAFMISRETENVQ SSQDVEAAFRALTSGEKPYITAQELFANLTKEQADYCTQRMKLYEDSSGREVPDAYDFVT FTHDIFVNALQCYQCDSNEDASCPSNKRFDKNLNALVDCNSMEAHTPGTFCMKVTQQSPG WRAWKKVTRRCGSRSDTGVAWGCRWEYEMNGVWKEVCYCEDRDGCNSATSXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX X----------------------RVFVWDLDETIIIFHSLLTGSYAQRYGKDAPSSVSLG LRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSNYNFATDGFHAAA------ -----------------------------------------EAWLQLRSEIEGMTDNWLT LALKSLSIINSRSSCVNVLVTTTQLVPALAKVLLYGLGGVFNIENVYSATKIGKESCFE- ----------------------------------------------------ASPLIVGG DRTTGQSVRTQNVLAASSIANIVKSSLGPVGLDKMLVDDVGDVTITNDGATILKLLEVEH PAAKVLVELAELQDQEVGDGTTSVVIIAGELLKNADELVKCKIHPTSIISGFRLACKEAC KYIQEHMTISVDELGRDCIVNAAKTSMSSKLIGVDSEFFSNMVVDAAQAVKTSDGKGNYK YPINAVNVLKAHGKSARESILVNGYALNCTVASQAMPKKVVNAKIACLDFGLMKAKMKMG VQILVEDPEQLDQIRQRESDITKERIQKILATGANVILVTGGIDDLCLKYFVESGAMAVR RCLKKDLKRIAKATGATMVSTLANLEGEESYEATLLGAADEVSQERICDDELMVIKGPKA RSAASIILRGANDYYCDEMERSVHDALCVVKRVLESKTVVPGGGAVEAALSIYLENFATS LSSREQLAIAEFARSLLVIPKQLAVNAAQDSTDLVAKLRAYHNTSQTKSDRRELKWVGLD LHEGVVRDNKKAGVFEPAISKIKSLKFATEAAITILRIDDMIKLAPEDKGGPSYQDAMRA GTL-EEEALLLVSKNILNQFLVEGKDLTVEYSIFNVGGSAATNVQLLDASFPEDDFKVVH GNLNVRWHRIASKTNTSHVVIVRPLKAGYFNFTSAEVSYMASEDEPQIGYTSAPGQGGIM NFKDYDRKFSPHVLDWAAFAVMTLPSLGIPFLLWFSSKSKYEA-KAKKNSNGAPKERTEK YKALLDLVENLKAFVEALVNENVSLVISRQILSELCGQLPKLGDDVSKNVAHFTLEKVQP RVISFEEQVASIRQHLATIYEKELAWRDAANVLVGIPLETAQKQYTNDYKLETYLKIARL YLEDEDPVQAEAYINRASLLQSDSQNDELQIYYKVCYARVLDYRRKFIEAAQRYNELSYK NIVAESERMEALKNALICTILASAGQQRSRMLATLFKDERCQQLPAYAILEKMYLDRIIR SSDLQEFSALLQPHQKALTADGSTILDRAVIEHNLLSASKLYNNISFEELGSLLDIPPAK AEKIASQMITEERMNGYIDQIDSIVHFEAREALPSWDKQIQSLCFQVNNIIEKISNHAPD WMAKASEQQM---LTDTVVQSFRVAKVFRENTDRINNLDFSASGDTLISSSDDDSIIIYD CQSGTPKRTLNSKKYGVDLIHFTHAPNTAIHSSTKVDDTIRYLSLHDNKYIRYFPGHNKK VVTLCMSPIDDSFISGSMD----------------------------------------- ------------------------------------------------------------ --------------------------------------------------EHMGPVQCIQ FNPKYMMLASADMQMSFWLPQIDE--ILTETRGEKNNVGFIKLNRPKALNALNKELMEEL RDALDKFEDDPNIGAVVLTGSDRAFAAGADIKEMVPMTFPDVYYKSFLSNWDRLAHMKKP VVAAVNGYALGGGCEVAMMCDIIFAGQKALFGQPEILLGTIPGAGGTQRLTRAVGKSKAM EMVLTGEPITAQEALVAGLVSRVSEVENLVDEAVATAEKIAGLSKVVVQMAKESVNASYE LTLNEGIRFEKRMFHQTFATEDRAEGMKAFQEKRKADFKD >Haementeria_depressa XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX X----------------------------------------------------------- ---------------------------------------------------------RAC YGVLKFIMESGAKGCEVIVSGKLRGQRAKSMKFLDGLMIHSGDPMNDYVDQAVRHVLLRQ GVLGIKVKIMLPWDPTGKLGPKRPQPDHVTILDPKDQPLPEQPYSEQKGTKXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXRKQKQVKVTLGPQVAEGELVFGVAHIFASFNDTFXHVTDLSGKETIVRVT GGMKVKADRDESSPYAAMLAAQDVAERCKLIGITALHIKLRATGGNRTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRLMGKPRGLRTARKLKNHRREQRWNDKD YKKSHLGTRWKSNPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP WDGCLNFIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVASVSLLALYKGKKERPRSXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPRI SLVQSKTYSTPRRPYEKERLDQELKLIGEFGLRNKREVWRVKYALTKIRTAARELLTLDE KDPRRLFEGNALLRRLVRIGVLEESKMKLDYVLGLKLEDFLERRLQTQVFKLGLAKSIHH ARVLIRHRHIRVRKQVVNIPSFIVRLDSQKHIDFSLKSPYGGGRPGRVKR---------- --XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMPLAKDLLHPTQEEEKRKCKLKRLVQSPNSYFMDVKCPGCYKIMTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRRKQH-VRMNVLADALKSICNAEKRGKRQVLIRPCSKV IIKFLTVMMKHGYIGEFEIIDDHRAGKIVVNLNGRLNKCGVISPRFDIKMKDLEHWTAYL MPSRQFGYLVMTTSGGIMDHEEARRKHLGGKILGFFFMGRMHAPGKGISQSSLPYRRSVP TWLKLSSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTSNKILRILKAKGLAPE IPEDLYFLIKKAVAIRKHLERNRKDKDAKFRLILVESRIHRLARYYKTKKVLPPTWKYES STASALVSVVEAQDVKLFGKWSAEDVNINDISLTDYIAVKEKYAKYLPHSAGRYQAKRFR KAQCPIVERLTDSLMMHGRNNGKKLMAMRIVKHAFEIIHLLTGENPLQ------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------CGWDRIVKVWNLTNCKLKTNHYGHXGFLNTVTVSPDGSLCASGGRDSQAMLWD LNEGKHLYTLDGVDTINALCFSPNRYWLCAATGPSIKIWDLEGKVVVDELKPELINTS-K SPDCLSLAWSADGQTLFAGYTDKLIRVWQVSVTARXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXMSDAEGDDAPAVAAAGGPMDLNTAIQEVLKNSLIHDGLARGAHEC AKALDKRQAHLCVLANNCDEANYVRLIEALCAEHNINLIKVDDNKKLGEWGGLCKIDKEG KARKVVGCSCVVVKDYGKESPALDVLNEYFKSRKXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-YSTNANIVKPPGEKPDELERSISQ ALLELEMNSDMKAQLRELTFTGAKEVDVHNKKAIIVSVPVPQLRSYQKVQSRLVRELEKK FSGKHVVFIAQRRILPKPTRKTRRKNKQKRPRSRTLTAVHNAMLEDLCFPSEIVGKRIRI KTDGSQIIKVHLDKSQQTNVEHKLDTFTAVYKKLTGKDVVFEFPEYVLGRGGFRGGFGGR GRGRGRGRGRAKEGDKEWVPVTKLGRLVKDMKIKTIEEIYLFSLPIKEFEIIDFFLGSSL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDFNGHVGLGVKCSKEVATAIRGAIILAKLSI VPVRRGYWGNKIGKPHTVPCKVTGSCGSVEVR---------------------------- -----------------------------------------------------XXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXMKFNKSVSGSRRKNRRRHFNAPSHIRRKIMSSPLSKELRQKYNVRSIPIRKDD EVQVVRGHHKGAQVGKVVQVYRKKYIIHIERIQREKVNGATVHVGIHPSKVVIVKLKMDK DRKLILERKARSKQ-GKHSEESVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------- ---------------------------MHLRRAVAYLKNVIDHKECVPFRRFTEGVGRCA QAKAWGTTQGRWPKKSAEFLLQMLKNAESNAEFKGLDTDHLVIEHIQVNRAPKMRRRTYR AHGRINAYMSSPCHIEIILAEREQAIEKPKKX----------------XXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXMGISRDKWHKRRKTGGRMSQVRKKRKFELGRPPAHTKIGG RRIHTIRTRGGNKKYRALRLDTGNFSWGSEAITRKTRVLDVVYNASNNELVRTKTLVKNC IILIDSAPFRNWYEGHYALPLSRKKGVKLT---------------RKYEGRKKTAKVEPA LEEQFASGKILACVSSRPGQCGRCDGYILEGKELEFYQRKIKAKKGKMSLVLPDRFQHIL RVMNTNIDGKRKVPFALTAIKGVGRRYAHVVCKKANVDVTKRAGELTEEEVEKLITIMSN PRQYKIPDWFLNRQKDIKDGKYSQAMSNVLDSKIREDLERLKKIRAHRGLRHFWGL---- -------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRVRTK TVKKASRVIIEKYYPRLTLDFHTNKRLCEEIAIIPTKKLRNKIAGFVTHLMRRIQKGPVR GISIKLQEEERERRDNYVPEKSAIDEICPDTKEMLKLIDMAHIPNLQVITPIATAXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMRDIRILKL CLNICVGESGDRLTRAAKVLEQLTGQQPVFSKARFTVRSFGIRRNEKIAVHCTVRGAKAE EILDKGLKVKEYELRKGNFSETGNFGFGIQEHIDLGIKYDPNIGIYGMDYYIVLGRPGYN VSKKRRAVGKVGPQHRVTKEEAIKWFQQKYDGVILP--XXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX MVNVPKQRKTFCRGKKCRKHTLHKVTQYKKGKDSLFAQGKRRYDRKQSGYGGQTKPIFHK KAKTTKKIVLKMECTECKYRKQLAIKRCKHFELGGDKKKKGQMIQFXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX X-KRTKKVGICGKYGTRYGASLRKDIKKMEITQHGKYTCSFCGKETMKRKAVGIWTCKSC KKIVAGGAYIYSTTAAATVRSTIRRLKENKE-------------------------VPDP KIRIFDLGRKKAKVDEFPLCIHLVSDEWEQISSEALEAGRICANKYLVKHCGKDAFHLRV RLHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVDIGQIILSVRAKDAHKDKVI EALRRAKFKFPGRQKIHVSRKWGFTKWDREKFEPMRAEGVLVPDGCGVQYKPPHGPLAAW ----KVTKTLGRTGSQGQCTQVRVEFIDETNRSIIRNVKGPVREGDILTLLESEREARRL RXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXX------------------------------------------------------- ------------------------------AYKAKIKALFVMNKKDPYLVNFSKNVASGG VAGAMSLVFVYSLDYCRTRLANDAKASKKRQFNGMVDVYRKTIASDGLVGLYRGFVVSCI GIIVYRGCYFGFYDTLKPIVLGENAGLM-------------------------------- ---------------------------------------------------------XXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMQNDAGEYVDM YIPRKCSASNRIIAAKDHAAIQINLAEVDESTGRMTGQNKTYAICGNIRRMGESDDCLNF LCKRDGLLPKMVRGPRKHLKRVVAPKHWMLDKLGGVFAPRPSCGPHKLRECLPLVVFLRN RLKYALTYEEVKKILKQRLVKVDGKVRTDKTYPAGFMDVITIERTNEHFRLIYDAKGRFA VHRIQPEEAKYKLCKVKKILIGLKGIPSLVTSDGRTIRFPDPLIKVNDTVKVXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------VPNAAEYALAR IDDLINWGRKSSLWPLTFGLACCAIEMMHFAAPRYDMDRFGVVFRASPRQADCIIVAGTV TNKMAPALRKIYDQMPDPRWVISMGSCANGGGYYHYSYSVVRGCDRIIPVDIYVPGCPP- ---------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------ ------------------------------ETCLLDILDTAGQEEYSAMRDQYMRTGEGF LCIFAVNNCKSFEDINQYREQIKRVKDADEVPMVLVGNKVDLSSRTVDTKSAKDKADSFC IPYVETSAKTRQGVDDAFFTLVREI---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKIDLCV FSGYKIYPGHGKRVVKVDGKSYQFLNGKCAKAHLVKRNPRKVHWTVLYRRKHKKGLTEEV SKKRTRRTTKFQRAITGASLSDIIAKRNQKPEVRQAQREQAIRAAKEKAKAKEKSQPRV- ---MKLNISCPATGCQKLIEVDDERKLRAFYDKRLATEVSAECLGDEWKGYVVRISGGND KQGFPMKQGVLTNGRVRLLLKDGHSCYRMRRSGERRRKSVRGCIGDANLSVLSLVIIRKG DQEIPGLTDTTIPRRLGPKRASKIRKLFNLDKKDDVRQYVVRRPLP-------------- ------------------------------------------------------VKAKDL RNKKKDELLKQLDELKTELSQLRVAKVTGGAASKLSKIRTVRKSIARVLTVIHQTQKENL RKFYKPKDLRKKLTRAMRRALTPHELGIKSAKELHKKLAYPQRVYAIKAELKGPKVTDKV FFDIEIGGKKEGRVVIGLFGKTVPKTVKNFKTLAEGTETYKGSKFHRVIKDFMIQGGDFN KGDGTGGLSIYFPDENFKLKHYGAGWLSMANAGKDTNGSQFFITSKATDWLNGRHVVFGV VLEGMKVVRAIENVKKDRDRPLDDVVIADCGSLPVDQPFTVPKESAKEXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQQVYKLADVKSHNNSKSCWVVIHNDVYDVT KFLEEHPGGEEVLLEQAGSFATEAFEDVGHSTDAKEMMKQYKIGTLQDSDK--------- --------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------EGARMVRELFEMART KKACIVFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDT LDPALTRPGRLDRKVEFGLPDLEGRTNIFKIHARSMSVEKDIRYELLARLCPNSTG---- ------------------------------------------------------------ -----------GHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITI DISLWKFETSKYYITIIDAPGHRDFIKNMITGTSQADCAVLVVAAGVGEFEAGISKNGQT REHALLAYTLGVKQLIVGVNKMDSTEPPYSEARFEEIKKEVSAYIKKIGYNPEAVPFVPI SGWNGDNMLKMPWFKGWSVYSGVTILEALDNIDPPKRPTDKPLRLPLQDVYKIGGIGTVP VGRVETGVIKAGMIVTFAPVNLTTEVKSVEMHHQALEEAQPGDNVGFNVKNVSVKDIRRG NVAGDSKNDPPKETEEFKAQVIIMNHPGQISAGYAPVVDCHTSHIACKFRDLLEKIDRRS GKKLEDNPANVKAGDA-------------------------------------------- ---------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMSNISRDSLAESVAALLTKKRKFTETVELQISLKNYDPQKDKRFSGTVKLRNIPRPK MAICVLGDQQHCDEAKANTIECMDAEALKKLNKNKKLIKKLAKKYDAFLASDSLIKQIPR IVGPGLNKAGKFPTMLTHSESMTGKIEEVKATIKFQMKKVLC------------------ -----------------------------------XXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX >Harmothoe_extenuata MSERKAVIKNADMSEDMQQDAVDCATQALEKFNIEKDIAAYIKKEFDKKYNPTWHAIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSG-----RQFQTSAVQRDIDQAAKYIGAGAATV GAAGSGAGIGSVFGSLVIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLILFAF- --------------------LTSRNVKSLEKVCADLIRGAKEKQLKVKGPVRMPTSLFWL NFRQ-----------------HKRLIDLHSPSEIVKQIT----------------MDQVV QFIEPAKSFAKDSIRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNII V---QISKKRKFVADGVFKAELNEFFTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVL GEKGRRIRELTSVVQKRFNFPEGTIELYAEKVATRGLCAIAQAESLRYKLIGGLAVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGEPIHDYVNTAVRHVLLRQ GVLGIKVKIMLPWDPTGKTGPKNPLPDHVSIVEPKEEIMPTQPISEQKGGKMSKRGRGGS SGGKFRITLALPVGAVINCADNTGAKNLYIISVHGIKGRLNRLPAAGSGDMVMATVKKGK PELRKKVMPAVVIRQRKSIRRKDGVFLYFEDNAGVIVNNKGEMKGSAILGPVSRECADLW PRIASNAS--RKGKVTKVQLGPQAVEGENVFGVAHIYASFNDTFVHITDLSGKETIVRVT GGMKVKADRDEASPYAAMLAAQDVAERCKVLGITALHIKLRATGGNK------------- ---------------------------------------------KLRDHRRDQRWHDKD YKKSHLGTRWKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP RDGCLNFIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKEKKERPRSEGV VTLRTRKFLTNRLLNRKQMVVDVLHPGRATVPKTEVREKLARMYKTTPDVIFCFGFRTQF GGGKTVGFALVYDSLDFAKKLEPKYRLVRHG-------------------------MTRV PLVCSKTYTTPRRPFEKERLDHELKLIGEYGLRNKREVWRVKYTLAKIRKAARELLTLDE KEPRRLFEGNALLRRLVRIGVLDESKMKLDYVLGLRIEDFM------------------- ------------------------------------------------------------ --MGLTISNLFNRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVTEAQEELSKMLQEDELRD AVLLVFANKQDLPNAMNAAEITERLGLNQLRGRIWYIQSTCATQGQGLYEGLDWLSNEL- ---MPLAKDLLHPTVDEERRRCKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRKKAHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRMHAPGKGISKSALPYRRSVP TWLKVTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILRAKGL--- ---------------------------SKFRLILVESRIHRLARYYKTRKVLAPNWKYES SS------VAEAAQIQLFGKWSSEDVQVGDISLTDYIAVKEKYAKYLPHSAGRYQVKRFR KAQCPIVERLTSSLMMHGRNNGKKLMTMRIVKHAFEIIHLLTGENPLQVVVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVN---------------------------------- ------------------------------------------------------------ -------------GIPQKALKGHGHFVSDVVMSSDGQFALSGSWDGTLRLWDLSTGTTTR RFIGHNKDVLGVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIEDGH------------T QNPIIVSAGWDKLVKVWNLTNCKLKTNHIGHTGYLNCVTVSPDGSLCASGGKDGQAMLWD LNEGKHLYTLDGG----------------------------------DELRQEVISSSAE PPQCICLAW--------------------------MREYKLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKVVEVDGNQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKLARTFNCAFLETSAKAK INVNEIFCDLVRQINKKNPDTMSDDKK-GNEHINLRVIGQDGQVVHFKIKKNTPLRKLMT AFCERTQLRMESLRFRFDGQAINETDTPMQIEMEDGDSIDVFQQQTGGMSTLPMNPKPFL NGLTGKPVMVKLKWGMEYKGYLVSVDTYMNLQLANTEEYIDGAQTGNLGECLIRCNNVMY IRGVEEEEEDGEMKEMSDAEGDDVPSAAAGSGNMDVNTALQEVLKTSLIHDGLARGLREC AKALDKRQAHLCVLANNCDERNYVALVEALCAEHGINLMKVDDNKKLGEWAGLCKIDREG KARKVVGCSCVVVKDYGK----------------MAAIRKKLVIVGDGACGKTCLLIVFS KDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSI DSPDSLENIPEKWTPEVRHFCPNVPIILVGNKKDLRNDENTRRELAKMKQEPVKPEEGRA MAEKINAFGYLECSAKTKEGVREVFETATRAALQVKKKKKNRMDDFQSGEETAFVVDEVS NIIKESIEGAIGGNAYQHNKVNQWTSNVVEQCLNQLTKLGKPFKYIVTCVIMQKNGAGLH TASSCFWDNTTDGSCTVRWENKTMYCIASVFGMSIMFSASAKIIKPSGEKPDAFESSISQ ALLELEMNSDLKAQLRELHITAAKEIDVAGKKAIIIFVPVPQLRAYQKIQTRLVRELEKK FSGKHVVFIAQRRILPKPTRKNRSKSKQKRPRSRTLTAVHDAILEDLCFPAELVGKRIRI K-----------------------------------------------DRGGFRGGFGDR GRGRGRGRGRGAKEDKEWMPVTKLGRLVKDIKIKSLEDIYLFSLPIKEFEIIDFFLGTAL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDSNGHIGLGVKCSKEVAT------------- -----------------------------------------------------------C YTSARGQTGTLGNFAKATYAAIAQTY---------------------------MSGGLEC LSLKEEDVVKFLACGTHLGSTNSDFQCEQYIFKRKPDGVYIINLRKTWEKLLLAARAIAA IENPADVCVISARPYGQRAVLKFASATGATPIAGRFTPGTFTNQIQAAFR---------- -----------YVNIPVIALTNTDSPLRYVDVAIPCNNKGVHSIGLMWWMLAREVLRLRG TISREVPWDVMVDLYFYRDPEEAEKDPTKEDWAAEAVVPAVPIKADDWSAAETGDWSAAP TSNEWGGMKFNKMVSSSRRKNRKRHFNAPSHIRRKIMGSPLSKDLRLKHNVRSVPIRKDD EVQVVRGHYKGQQVGKVVQVYRK------------------VHMGIHPSKVVIVKLKMDK -----------------------GAASATSVGSTVRQRKTGSSGAGAAGMWRFYSEDSPG IKVGPVPVLVMSLLFIASVFMLHIWGKYTRG-----------------------EEVHGI GFKRRAPRAIRELKKFAEKMMGTPDVRVDT-------------------------RNEDE DSPHKLYTLITYVPVTTFKGLQTVNVDSAGKSEFLVYGKYRLVRKIGSGSFGDIYLGINI TSGEEVAVKLESHKARHPQLLYESKLYKILQGGVGIPHIRWYGEKEYNVLVMDLLGPSLE DLFNFCSRRFSMKTVLMLADQMIGRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKVFLIDF GLAKKYRDNRTRQHIAYREDKNLTGTARYASVNAHLGIEQSRRDDLESLGYVLMYFNRGT LPWQGLKAATKKQKYEKISEKKMATPVEVLCKGYPAEFAMYLNYCRGLRFEEAPDYMYLR QLFRILFRTLNHQYDYVFDWTILKQKAAKAMNAEKLKMRIGGKGTARRKKKVVHRTATTD DKKLQSSLKKLQVSNIPGIEEVNMIKEDGTVIHFNNPKVQAALAANTFAITGHAETKQMT EMLPGILNQLGAESLASLKKLASAAGDIDDDDDEVPDLVENFDEASKGEMTRYSLDAENA TKSAKARGSHLRVHFKNTRETAHNIKHMHLRRAVSYLKNVANHVECVPFRRFNGGVGRCA QAKAWGAT---------------------------------------------------- ------------------------------------------------KKTGPKPELTEE QKQEIREAFDLFDADGTGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKDGSGTVDFND FLSLMTVKMSEKDSKEEIMKAFRLFDDDETGKISFNNLKRVAKELGENLTDEELQEADRD GDGEINEQEFLRIMKKTSLYMGISRDTWHKRRKTGGRQAPIRKKRKFELGRPAANTKLGV KRVHTVRTRGGNTKFRALRLDTGNFAWGSEATTRKTRIIDTVYNASNNELVRTKTLVKNA IVQVDAVPFRQWYEAHYAQPLGRKKGVKL------------------------------- -----------------------------------------------XXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXX---------------------AGLADELVSKAKQSRSEKKA RKAMSKLGLKQVAGVSRVAIRKSKNILFVINRPDVYKSPASDTYIVFGEAKIEDLSQQAQ VRAVDQFKAEEEVDESGVEAKDIELVMSQANVTRAKAVKALKNNQNDIVNAIM------- ------------------------------------------------------------ ----KYKEEERERRDNFVPEISAIEEV----------------------------MKWEY KEEHPFEKRRAEGEKIRKKYPDRVPVIVEKAPKARVGDLDKKKYLVPSDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGALYQEHHEDDFFLYIAYSDESVYGMRELRITKL CLNICVGESGDRLTRASKVLEQLTGQQPVSSKARYTVRSFGIKRNEKIAVHCTVRGAKAE EILEKGLKVREYELRRGNFSVTGNFGFGIQEHIDLGIKYDPGIGIYGMDFFIVLGRPGFN VPHRRKKVGVVGPKHKVTKDEAMKWFQQKYDGVILPGKMGIKFLEFVKPFCSVLPEIAKP ERKIQFREKVLWTAITLFIFLVCCQVPLFGIMSSDSADPFYWMRVILASNRGTLMELGIS PIVTSGLIMQLLAGAKIIEVGDTAKDRALFNGAQKLFGMVITVGQAIVYVMTGMYGDPAE IGAGVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVN TGRGTEFEGAIIALFHLLATRTDKVRGLREAFYRQNLPNLMNLLATVFVFAIVIYFQGFR VDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAAKFSGNFIVNLLG VWADVGSGGPARSYPIGGLCYYLSPPETLSHVGEDPIHAVLYIVFMLGSCAFFSKTWIEV SGSSAKDVAKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFMGAIG SGTGILLAVTIIYQYFEIFVKEQSEMGGMSTLLFQAERAFQKQPTVFLNKKKATLLRYVR NVGLGFKTPRDAYDGSYIDKKCPFTGDVSIRGRILTGVITKLKMQRTCVIRRDYLHYIRK XNRFEKRHKNMSVHLSPAFRDVSTGDIVTVGECRPLSKTVRFNVLKVTKGSG-KKGFSKF ------------------------------------------------------------ ---------LKMECSSCKFKKQLSIKRCKHFELGGDKK--------MGRVIRSQRKGPGS VFKAHTKHRKGAAKLRAVDFAERHGYIKGVVKDIIHDPGRGAPLAKVCFRDPYRYKLNTE TFIASEGMYTGQFLYCGKKAALQVGNILPVGSMREGTIIC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ -AKRTKKVGITGKYGTRYGASLRKTIKKMEITQHGKYTCSFCGKETMRRKAAXIWNCRSC KKIVAGGAYVYSTTAAATVRSAVRRLRES--MGRRPARCYRYCKNKPYPKSRFCRGVPDP KIRIFDLGRKKASVDDFPLCVHLVSDEYEQLSSEALEAGRICANKYLVKTCGKDAFHLRM RPHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQ--------------VI EALRRAKFKYSGRQKIFVSNKWG---------------GHLVHDGVGVQYKPEHGPLKAW MAARKVTKVLGRTGSQGQCTQVRVEFLDDSNRSIIRNVKGPVREGDILTLLESEREARRL R------------------------------------------KMRKYNWSEKACRRRTT GVGRMRHMKNVFRRFKNGFREGTEAKPRRKMVEDRASAKELNQWIEQLNECKQLTENQVK TLCEKAKEILTKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDR GYYSVETVSLLVALKVRYKDRITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDSQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHSNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRC GNQAAIMELDDALKYSFLQFDPAPRRGEPHVTRRTPDYFLMGAYKYIQELYRKKQTDVLR FLFRVRCWQYRQLSAVHRAPRPSRPDKARRLGFRAKQGYVIYRVRVRRGGRKRPVPKGAT YGKPTNQGVNSLKFQRSTQSVAEERAGRKCKGLRVLNSYWVAQDSTYKFFEIIMIDTFHK AIRRDAKINW-------HREMRGLTSAGKKSRGLGKGHKFNGTIGGLR------------ ----GIALARLSEERKGWRKDHPFGFVAKPTKNPDNTLNLMNWECAIPGKKGTPWEGGLY RLRMIFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSLLDEEKDWRPAVTIKQILLGIQE LLNEPNIRDPAQAEAYTIYCQNKLEYERRVREQALKFRD---GKSSKMLQHINYRVRCTL QDGRIFIGTFKAFDKHMNLILGDCDEFRKVKPKKSKEREEKRVLGLVLLRGENLVSMTVE GPPPAEEGIARVPLPGAGGGPGMGRAAGRGIPAAAGLQGPVRGVGGPSQQAMQPQRGM-- GGPPQERITFKLVLVGDGGVGKTTFVKRHLTGEFEKKYVATLGVEVHPLPFNTNRGEIYF NVWDTAGQEKFGGLRDGYYIQGQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCG NKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLVGDPNLEFVAMPA LAPPEVIMDPNMAAQYEQELKIAQETALPDEDDDLNEGIKQYYISKIEELQLVTTEKTQN LRRLEAQRNELNAKVRMLREELQLLLEQGSYVGEVVKPMDKKKVLVKVHPEGKFVVDLDK NIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEI KEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ KFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRLESGSGGDSEVQRTMLELLNQLD GFEPKQNIKVIMATNRIDILDSALLRPGRIDRKIEFPAPNEEARSDILKIHSRKMNLTRG INLRKIAEMMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFELAVAKVMQKDSEKNMSI KKQWKLGFAENFALSGAAAVISKTAAAPIERVKLLVQNQDEMIKQGRLDRPYKGVIDCTA RTFQTEGLLPFWRGNLANCIRYFPTQALNFAFKDKIKAMFKSSKNESQAVKFGKNIASGG AAGALSLTFVYSLDYARTRLANDAKGGAKREFNGLIDVYKKTLKSDGIQGLYRGYVISCV GIIVYRGCYFGFYDTLKPLLLGEDAGLMASFALGYVVTISAGLVSYPIDTIRRRMMMTSG QAVKYKGSIDCAVTVIKGEGFMSLMKGAGANILRGVAGAGVLSGFDAFKGVYMAWRL--- -SDLDRQIEQLRRCEIIKESEVKSLCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLK ELFKVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQV YGFYDECLRKYGSITVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRAIDRK QEVPHDGPMCDLLWSDPEDTQGWGVSPRGAGYLFGSDVVAQFNAANDIDLICRAHQLVME GYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLRRDFTIFEAAPQESRGKPQADYFL VRLPPEVNRILYVRNLPYKITAEEMYDIFGKYGAIRQIRVGGTPETKGTAFVVYEDIFDA KNACDHLSGFNVCNRYLVVLYYQSNKAFKKLDAEKKKDELDRMKAKYGLSTPEI-MSIGV PIKVLHEAEGHIVTCETKTGEVYRGKLVEAEDNMNCQMANITVTYRDGRVAQLENVYVRG SKIRFMILPDMLKNAPMFKKVGAGRGKSAILRAAARGRGRGGGG---------------- -----------IINAKDHASIQVNLCVVDPTTGRMTGQ---------------------- ----------MVRGPKKHLKRLHAPKHWMLDKLGGVFAPKPSSGPHKTRECLPLMLFLRN RLKYALTYTECKKILHQRLIKIDNKVRTDQTYPAGFMDVIKIEKTAENFRLIYDVKGRFA VHRISPEEAKYKLCKIKKVGTHQKGVPFVVTHDGRTIRYPDPLVKV------MGTKDDEY DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTA GQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADNNIVIMLVGNKSDL RHLRAVPTDEAKAFAEKNNLSFIETSALDSTNVETAFQNILT-IYKIVSQKQIRDSKDDN NVQTISVGPTDTFAERRKQCC-MSARYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVR GKDMVVLGVEKKAVAKLQEDRTVRKIALLDDHVAMAFAGLTADARILINRARVECQSHKL TVEDPVTLEFITRFIAQLKQRYTQSNGRRPFGLSALIIGFDGTPRLYQTDPSGTYHEWKA NAIGRSSKTVHEFLEKHYTEEISSEKETVKLALKALLEVVQSGSKNMEIAIMRRGEKLQM MESEEVEKYIAEIEKEKEEEAEKKKQKGGGQGGDKKDDKDKKRKYEPPVPTRVGKKKKKL KGPEAANKLPMVTPHTRCRLKQLKLERIKDYLLMEEEFIKNQERLKPQEEKQEEERSKVD DLRGTPMSVGNLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDQLEPGCSVLLNHKVHAVV GVLGDDTDPMVTVMKLEKAPQETYADIGGLDAQIQEIKESVELPLTHPEYYEEMGIRPPK GVILYGQPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPS IVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPA LIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTLADDVKIDDYVMAKDDLSGADIKAICT EAGLLALRERRMKVTDEDFKKAKENVLYRKAEGTPEGLYL-RKPYSPFQKNNTAEYALAR VDDLVNWARKGSLWPLTFGLACCAVEMMHFAAPRYDMDRFGVVFRASPRQADCIIVAGTV TNKMAPALRKVYDQMPDPRWVISMGSCANGGGYYHYSYSVVRGCDRIIPVDVYVPGCPPS AEALLYGVLQLQKKIKRMNLTQQWYRKTDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYA NNSNYKNDTMIRKEAFVHKSVMDELKRIIEDSEIMKEDDGMWPQPDRVGRQELEIVIGDE HISFTTSKIGSLVDVNQSKDPEGLRTFYYLIQDLKCLVFSLIGLHFKIKPIXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMTEYKLVVVGAGGVGKSA LTIQLIQNHFVEEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGF LCVFAVNNTKSFEDINQYREQIKRVKDADEVPMVLVGNKVDLQSRTVETKEGSALSASYG IPYIETSAKTRQGVDDAFYTLVREIRKYMGDRYNIHSQLEHLQSKYIGTGHADTTKWEWL TNQHRDSHASYMGHVDMLNYFSLVENET-------------------------------- ------------------------------------------------------------ --------------------TDILAKRNQKPEVRKAQREQAIRAYKE------------- ----ELNIAYPATGCQKLIEVDDEKKTRFFYDKRISAEVPA------------------- --------------------------------------SVRGCIVDGHLSVLNLIIVKKG EKEIPNLTD---------------------------------------SKAPKIQRLVTP LVLQRKRHRIAMRKKR-------------------------------------KVKAKDL RGKKKEELTKQLEELKTELSALRVAKVTGGAASKLSKIRIVRKSVARVLTVIHQTQKENL RKFYKPKDLRKKL-----------------------------------KAAKGPKVTDKV FFDITIGGEAAGRVVIGLFGKTVPKTVKNFKTLAEGTFTYKGSKFHRVIKDFMIQGGDFT RGDGTGGKSIYFADENFKLKHYGPGWLSMANAGKDTXGSQFFITTKTTPWLDGRHVVFGK ILEGMDVIRKVENTDKDRDKPTKDVLIADCGSLPVDTPFAVAKEAAEE------------ ------------------------------------------------------------ ---DWLRVVANNKDSYELRYFQINNEEEEE----------EDEKVYGGCEGPDAMYVKLV SSDGHEFIVKRDHALTSGTIKAMLSGPGQFAENETNEINFREIPSHVLQKVCMYFTYKVR YTNSSTEIPEFPISPEIALELLMAANFLDC-----LEELKQHKDGKSLWMAIHDKVYDVT KFLEEHPGGEEVLLEQGGGFATEAFEDVGHSTDARELMEQYEIGELPEDERGGISGWLIP LGIAIVAALVYKYVMSYMLQHLYNGWQVDQAILSEEDRVIIIRFGHDWDPTCMVMDETLY RCAEKVKNFAVIYLVDNTLVPDFNKMYELYDPCTVMFFYRNKHIMIDLGTGNNNKINWAM EDEQEFVDIVETLYRGARKGRGLVVSPKDYSTKYRYKKLQRQLEFLEVLEEYIKDEQKNL KKEHLHAQEEVKRIQSVPLVIGQFLEAVDQNTGIVGSTTGSNYYVRILSTIDRELLKPSA SVALHKHSNALVDVLPPEADSSITMLGADEKPDITYSDIGGMDIQKQEVREAVELPLTHF ELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVR DVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTVNVKVI MATNRSDTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITGKMNLSEEVDLEDYVARPD KISGADINAICQEAGMQAVRENRYVVLAKDFEKGYKNNIKKDETEHEFYKAHQPLSLESI RERVLLVLKLYDKINPETLTVDSHFMNDLGLDSLDHVEVVMAMEDEFGFEIPDSDAERLM RPADVVQYIADKEDV-RRVQTMPDDLRFVEFETSEEVEVTPTFDSMGLRDDLLRGVYAYG FEKPSAIQQRAIKPIVKGRDVIAQAQSGTGKTATFSISILQCLDTQVRETQALILSPTRE LAGQIQKVILALGDYMNVQCHSCIGGTNIGEDIRKLDYGQHVVSGTPGRVFDMIRRRNLR TRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVCLISATLPHEILEMTSKFMTDPI RILVKRDELTLEGIKQFFVAVEKEEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTDKM REANFTVSAMHGDMPQKEREAIMKEFRSGASRVLITTDVWARGLDVQQVSLVINYDLPNN RELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDIEQFYSTQVDEMPMNVADLIMSLRRP FDPVAHDLDAKFRLTSFADLKGGCKVPQEVLLKLLEGL-QSQESEQGHFQFVANVPRIGI GMDSCVTPLRHGGLSLVQTTDFFYPLVDDPYMMGKIACANVISDLYAMGVTECDNMLMLL GISQKMTDKERDVVVPLMLRGFRDLAEEAGTSVNGGQTVMNPWLTIGGVATTACQANEFI MPDSAVVGDVLVMTKPLGTQVAVNAYQWLGT-EKMNRIRLVVSEEEVKKAYQRAMFSMAR LNRTAARLMHKYNAHGATDITGFGMLGHATNLARIQKNEVSFVIHNLPVIAKMASVSKAC GNMFGLLQGHSAETSGGLLVALPREQAAAFCKDIEKQEGYQAWIIGIVEKGNRTARIIDK PRVIEVPAKEKE----------GFFINIDAHAEECFFDKVSSGTKMSLMFEVAEGGFLDI DVKIVGPDGKNIYSGDRESNGKYTFAAHMDGIYKYCFSNKMSTMTPKIVMFTMDIGEKPK AHHNKLEEMIGELSQSLTGVKHEQEYMELRERIHRAINDNTNSRVVLWSFFEALVLVAMT LGQIYYLKRFFEVRRVV--SSLQPYLNAVRHTLTAAMCLENFSSQVVERHNKPEVEVRTS KELLLTPVVISRNPKERILIEGSVNSLRISIAVKQADEIEKILCHKFMRFMMMRAENFVV LRRKPVPGYDISFLITNFHTEAMYKHKLVDFIIHFMEEIDKEISEMKLAVNSRARISAEE FLKRFSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLV TMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTMPNTFKTLDSWRDEFLIQASPRDPEN FPFVVIGNKIDLENRAVSTKRAQSWCHSKGDIPYFETSAKEAINVEQAFQTVAKNALAQE TEVDLYNEFPDQIKLTNDAVRDGCG-TAPFDARFPNQNQTRNCWQNYVDYHRCHKVDDYE PCEYFKGVYRSLCPNEWTTRWDDQMEAGAFAGKIMPDHLGKDQRRTLDDEKEDKPIQVLD EGDIALLKTYGTGQYHRSIKTVEEDIQNILKRVNELSGIKESDTGLAPPALWDLAADRQT LQSEQPLQVARCTKIINADSEDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNK YQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIDKLREVVETPLLHPERFVNLGI EPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMART KKACIIFFDEIDAVGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDT LDPALMRPGRLDRKVEFGLPDLEGRAHIFKIHARSMSVEKDIRYELLARLCPNSTGAEIR SVCTEAGMFAIRARRKMATEKDFLEAVNKVIKAYAKFSATPRYMTYNMGQEKFHINIVVI GHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITI DIALWKFETTKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVA----------SKNGQT REHALLAYTLGVKQLIVGINKMDNTEPPYSASRYEEIVKEVSSYIKKIGYNPETVPFVPI SGWHGDNMLNMTWFKGWSV---------------------------DKKVYKIGGIGTVP VGRVETGSLKPGMVVTFAPAAITTEVKSVEMHHTALEEALPGDNVGFNVKNVSVKDIRRG NVCGDSKDDPPFETKEFKAQVIILN-----------------------------KIDRRS GKKLEDNPAHVKSGDAAIVNMVPQKAMCVESFNQYPPLGRFAVRDMRQTVAVGVIKEVTK NTGGPSKVTKAAQKAELEQLRQEAEQLKNQIREARKAAADTTLSQAAGNVEPVGRIQMRT RRTLRGHLAKIYAMHWSSDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAP SGSYVACGGLDNMCSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIVTSSGDMTCA LWDIETGQQTTSFTGHTGDVMSLSLSPDMRTFVSGACDASAKLWDIRDGMCKQTFSGHES DINAITYFPNGFAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLG GYDDFNCNVWDTLKQDRAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKIWNMSYAYLF KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES FRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLEARR DVKKEEGEAFAREHGLIFMETSAKTAANVEEAFINTAKEIYQRIQDGVFDINNEANGIKI GPQHSPTSPAGGGGAKPGGGMTRGRTELGDVTVHNLKQLKRLNQVVFPVTYNDKFYKDVL DVGELAKLAYFNDIVVGAVCCREDKSEHQRRLYIMTLGCLAPYRRLGIGTVMLEHVLKIC KDDGNFDNVFLHVQVNNDSAIKFYERFGFEIVERKANYYKRIEPADAFVLQKTFRQMPRQ IMEIKDFLLTARRKDAQSVKIKKNVKF--------------------------------- ---MSKISRDALTEAVTAVLQKKRKFTESVELQIALKNYDPQKDKRFSGTVKLKHIPRPK MRVCVLGDQQHCDEAKXNDVSFMDAEALKKLNKNKKLVKKLAKRYDAFLSSDSLIKQIPR ILGPGLNKAGKFPTLLTHTESMMSKVDEVRGTIKFQMKKVLCLAVAVGHVNMTPEELTSN INMSINFLVSLLKKNWQNVRALYIKSTMGPAQRIYMADADKLNIDSIIARLLEVRGSRPG KNVQLTEFEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLNAGRPVTPPRGTAKNK GKMMFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEIVGTNVSTT YITCPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPF ICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDEL PAEFKLYLPVQNKMTEITIQNFQNPFQEHNEIHVRIQQRNGRKTLTTVQGIAAEFDKKKI VKFCKKDFACNGTVVQHPEYGEIIQLQGDQRNKIGLFLTRAGLEDQIKLHGFSAIFNFQS LLTIVLLLICTCAYIRSIAPRMLDKNKEGMLGIFWKCARIGERKSPYVAVCCIGMAFSIL FLSSARVAASLARQLPRAVSQRNTVGAGFVACRKFTTAAEVSAILEERILGASQADLEET GRVLSIGDGIARVYGLKNIQAEEMVEFSSGLKGMALNLEPDNVGIVVFGNDKLIKEGDVV KRTGAIVDVPVGEGILGRVVDALGNPIDGKGELPNVTRARVGTKAPGIIPRISVREPMQT GIKAVDSLVPIGRGQRELIIGDRQTGKTAVAIDTIINQKRFNEGTNEKAKLYCIYVAIGQ KRSTVAQIVKRLTDAGAMKYTIIVSATASDAAPLQYLAPYSGCAMGEYFRDNGKHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDNFGGGSLTALPVIE TQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTKAMKQVAG SMKLELAQYREVAAFAQFGSDLDAATQQLLNRGVRLTELLKQGQYVPMAIEEQVSVIYAG VRGYLDKIDPARITAFENEYLAHLRASQQETLKTIAADGQITPATDAKLKEIVTTFLAGF MEAILAIPFSVLEIPNLKIKKPTWVKQPSSMVVFAMVLMSYFLVTGGIIYDVIVEPPSIG STTDERGNSKPVAFMPYRVNGQYIMEGLASSFLFTMGGLGFVILDQVNKPTTPKLNRILM LCIAFVSILVSFFMCRVFMRMKLPMPKVKRSRKPPPDGWELIEPTIDELDQKMRESETEP HEGKRKVEALWPVFKIHHQKSRYIYDLFYRRKAISRELYDYCIKEGIADKNLIAKWKKQG FENLCCLRCIQTRDTNFGTNCICRVPKGKLEEGKIVECVHCGCRGCSGEYAQVTRMLGNG RLEALCFDGSKRLCHIRGKLRKKVWINNSDIVLVGLRDYQDKKADVILKYTPDEARNLKA YGELPESAKINDDIDDNITFDEIDDILVRFLMKLSHETVTMELKNGTQVHGTIVGVDVSM NTHLKTVKMTLKNKDPVQLDTLSIRGNNIRYFILPDSLPLDTLLVDDTPKAKSKKSLMQK PKSEMSPEELAQREQEEFNTGPLSILTQSVKNNTQVLINLRNNKKLLARVKAFDRHCNMV LENVKELWTEVPRTGKGKKKSKPVNKDRYISKMFLRGDSVILVVKNPLPIVIDGRGHLLG RLAAIVAKTTLQGQRVVVVRCEELNISGSFYRNKLKYLSFVKKR---------------- ------------------------------------------------------------ --RLSHEVGWKYQGVIATLEAKRKAKSNLF-----------------------------K GDPAKGKKVFVQRCAQCHTVESGGKHKTGPNLSGLFGRKTGQASGFSYTDANKDKGITWG KDTLWIYLENPKKYIPGTKMVFAGLKKKTDRADLISYLEESTKIFVERTLAIIKPDALAE EIEDIILRSGFTILQKRRVHMSPEQASDFYVEHYGRLFFPSLVVYMSEGPIIVMVLAREK AISYWRELIGPTNTLTARQTHPDSLRAIYGTNDQRNGLHGSDSYSTAAREIRFFFPDSVV EPVPLGQAAKDYL------------------------------------------MFEAR LVQGSILKKTLEAIKDLLTEATWDCSSTGISLQAMDSSHVSLVSLALRSDGFDTYRCDRN LAMGIKLASMSKILKCASNDDAITLKGEDDGDTITFMFESSNGEKVSDYELKLMDIDQEH MGIPETSYSCVIKMPSAELQRICRDLSQIGESVVICCTKEGVKFSATGDLGTGNIKLAQT ANVDKEEDAVIIEMQEAITLTFALQYLNFFTKATPLS----------------------- ----------------KCVSSYHTTQSVAGGRVVAVIGAVVDVQFDDVLPPILNALEVEN RTPRLVLEVAQHLGENTVRTIAMDGTEGLVRGQVCKDTGTPIKIPVGPETLGRIINVIGE PIDERGPVNSKAFAAIHAEAPEFVEMSVEQEILETGIKVVDMLAPYAKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVISLKDDTSKVSLVYG QMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTTKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIS ELGIYPAVDPLDSTSRILDPNVVGAEHYQIARGVQKILQDYKSLQDIIAILGMDDLSEDD KLTVARARKIQKFLSQPFQVAEVFTGSAGKLVPLKDTIKGFKAILEGDMDHLPEVAFYMV GPIEEVVTKADRLAAERMLMPKKNRIAIFEHLFREGVMVAKKDFHAAKHPELEVPNLHVI KALQSLKSKGLVTEQFAWRHFYWYLTNEGIQYLRDFLHLPPEIVPSTLKRQSMGDDRGAY RRG--------------MGKQNSKLKPEVLQDLRQSTEFSEDEIQEWYKGFLKDCPGGHL SVEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFICALSVTSRGKLEQKLKW AFSMYDLDGNGYISRQEMLEIVTAIYKMVGTVMKMPEDESTPEKRTDKIFRQMDKNLDGK LSLEEFIEGAKSDPSIVRLLQCDP------------------------------------ ------------------------------------------------------------ MIEKWQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCSKCQDVYTPKSSRHHHTDG AYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPLAYQLQYQAAANFKMGYNNGKR MTNTKGYRRGTRYMFSRQFRKHGVTKLSTYMKMYKRGDIVDIKGDGAIQKGMPYKAYHGR TGRIFNVTQHAVGVIVNKRVKGRIIPKHLNIRVEHIKHS--------------------- ----------------------------------------SNYKQVSPEDPSMEWKDITD RAATSAFWLELMKGMSIVGSNIFKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAICPAQAITIEAEERADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEY TTETHEELLYNKEKLLENGDKFEVEIAANLQADHLYRMATQAKIAKTEGKNNHDADKEQQ EAIEQIDEVQNEIDRLNEQASEEILKVEQKYNKLRQPFFSKRSELIAKIPNFWVTAFINH PQVSALLNEEDEEALQYLTKVEVQEFEDIKSGYRIKFHFDTNPYFENDVISKEFHLNSSN STTIKWKAGKDLTKKSKKRNHEEQESFFVWFSDHGDAGADELGEVIKDDIWPNPLQYYLA SEIDEEEPDEEGLEDEE------------------------------------------- ----------------------LSYKNVKFLLKHKIAQRREDAVSREVMKKVADDKRMSK KEKDERVLWKKNDVADYEATTFAIFYNNALYLVLIIVASFYVLRSFSPTFNYILSVGSAG GLLALFSTSTKATQGKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQT VCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVKELQRQ ASPNIVIALAGNKADLRMVEYEEAQAYAEENSLLFMETSAKTAMNVNDIFLAIAKKLPKN EPGVDITQDNMAEYLASIFGTEKDKVNCSFYFKIGACRHGERCSRLHNRPTFSQTVLIQN LYINPQNTAQIMLSDMEAQEHFDEFFEEIFTEIEDKYGEIEEMNICDNLGDHLVGNVYIK FRYEEDAEKGVADLNNRWFNGRPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKP ISRELRRQLYGRSRKSRSRSPPTRR--------------------MFLTRSEYDRGVNTF SPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVVLAVEKRVTSTLIEPSSIEKVFEVDSHIG CAMSGLIADSRTMIDRARVEAQNHWFTYNEKMSVESVTQAVSNLALAFGDDDADPGAMSR PFGVALLFGGIDEKGPRLFHMDPSGTFIQYDAKAIGSGSEGAQQSLQEVFHKSMTLKEAC KHALTILKQVMEEKLNSTNVELGTVTPERQFHMYTTEELEEVIKEIAQKTWELSNNIESG PTVDDIYRYDKKQHQDILTAKPWDKDPHYFKHIKISALALLKMVMHSRSGGNLEIMGLLL GKVDGPTMLVMDSFALPVEGTETRVNAQAQAYEYMAAYIESAKSVGRLENMIGWYHSHPG YGCWLSGIDVSTQMLNQQFQEPFVAIVVDPVRTISAGKVNLGAFRTYPKGYKPPDEGPSE YQSIPLSKIEDFGVHCKQYYSLEASYFKSSLDRRLLESLWNKYWVNTLSSSSLITNADYT TGQIFDLADKLEQSEAQLGRGGFMEKKSEDKLAKATKDGCKNTYEAIHGLMSQVIKDKLF NQVGGLPRRIIKETQRLVAEPVPGIVATPDDGNARYFHVTVAGPEESPYEGGTFKLELFL PEEYPMSAPKVRFMTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPD DPLANDVADMWKLDEAHAI------------EEDELLDYD---EEETKAVKGTYVSIHSS GFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILSMDVLCQAKSGMGKTAVFVLATLQ QLEPVDGQVSVLVLCHTRELAFQISKEYERFSKYMNNVKVAVFFGGMSIKKDEEVLKKNC PHIIVGTPGRILALGKTLNLKHAKHFILDECDKVLEQLDMRRDVQDIFRMTPHEKQVMMF SATLSKDIRPVCKKFMQDPMEVYVDDDSKLTLHGLQQHYVKLKDNEKNRKLFELLDALEF NQVIIFVKSVQRCMALSQLLVEQNFPAIAIHRVMTQEERLSRYQQFKDFQKRILVATNLF GRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDETDAKVPPSYGDLG KSARDIFNKGFNYGFYKLECKTKTANAVEFTTNGSSNHDTSKVTGSLETKYKLPDYGLTF QEKWNTDNTLGTEITIEDQLAKGLKLAFDTQFAPQTGKKSGKIKAAYKQDYINVNCDVDF DFAGPTI-XAAVLGYNGWLAGYQMSFDKSKLSKSNFAVGYKGGDFTLHTNVNDGSEFGGS YYQKVNDELECGVQLSWTAGSNATRFGLAAKYTPDRDSTFRAKINNSSQIGLAYQQKLRD GVTLSVSSLIEGKSFNQGGHKVGLGLDLAADSVREKALTDYRKKLLEHKELEARLKEMRE QLKELTKQYEKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQIDKSK LKAGTRVALDMTTLTIMRYLPREVDPLVYNMSVEDPGEIGYSQIGGLGEQVRELREVIEL PLMNPELFMRVGITPPKGCLLYGPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIGES ARLIREMFAFARDHQPCIIFMDEIDAIRRFSEGTSADREIQRTLMELLNQMDGFDALGQV KMIMATNRPDTLDPALLRPGRLDRKIEIPLPNEQARMEILKIHAQPIAKHGEIDWEAVVK LSDDFNGADLRNVCTEGGMFAIRAERDYIIEEDLMKAVRKVGENKKLESKLDYKPL-ADT LLSVVSKFYDEYMSGTPKKLKIIDSYLTYVLLTGVVQFLYCCLVGTFPFNSFLSGFISCV GAFVLAVCLRIQVNSQNKNEFLGISPERAFADFIFASVILNLVVVNFIGTLVSPSQLLPL ELVDKCIGSRIHIIMKNDKEIVGTLLGFDDFVNMVLEDVTEFESTPEGRRVTKLDQILLN GNNITMLVPGGEGPEVIDHYENPRNVGAMDKNDLSVGTGLVGAPACGDVMKLQIQVDEDG KIVDAKFKTFGCGSAIASSSLATEWVKGKTLDEAGSIRNTDIAKELCLPPVKLHCSMLAE DAIKAALSDWKSKN-MLVLVLGDLHIPHRSSSLPSKFKKLLVPGKIQHILCTGNLCTKDS FDYLKTLASDVHVVRGDFDENMNYPEQKVVTVGQFRIGLCHGHQVVPWGDTESLALIQRQ LDVDILITGHTHKFEAFEHESKFYINPGSATGAYNALDS-IIPSFVLLDIQQSTVVAYVY QLSGDDVKVERIEYKK-------------------------------------------- ----------------------------------HLMPTRYTAISLNKSVVNKDSFKDPA LR-----------------------------ERTFLMIKPDGVHRGLVGEIIKRFETKGY KLVAFKFMQATEGILSQHYAEHEGKPFFDGLLQYIMSGPVVPMVWEGEVISTGRNIIGAT NPLKAPPGTIRGDYGLVMGRNLIHGSDSEESSQREISIWFTEEELVDWVPNQNTWIYE-A APKPVKTAGKTKEKALRAKKNVLRGVHGKRVRKIRTTVKFRKPKTLALPRAPKYPRKSTP RRPRMDQFSIVKYPLTTESAMKKIEDNNTLVFIVHKQSNKPQIKMAVKKLYDIDVSKVNT LIRPDGEKKAYVRLA---------------MPSKQRMRIANDKASKNVGMRGNVPKTLKA AEEKYPVGPWLLALFLFVVCGSAVFQIIQSIRMVKIRSWTAVATWRWVANDDNCGICRMP FDGCCPDCKLPGDDCPLVWGQCSHCFHIHCIVKWLNSQQVHQLCPMCRQEWKFKEMIRFI LIQNRAGKTRLAKWYMHFDDDEKQKLIEEVHAVVTIRDAKHTNFVEFRNFKIVYRRYAGL YFCICVDVSDNNLACLEAIHNFVEVLNEYFHSVCELDLVFNFYKVYSVVDEMFLAGEIRE TSQTKVLKQLLMLSSLEQPTIFSKIIDKSIPADILYEDDQALAFRDVQPQAPKHFLVIPK QIIPGISQDKDLLGHLLLVARQVAKEDSGYRIVINNGQDGAQSVYHLHLHVMGGRQMNWP PMGGLLSYFSGLFGSKERRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVTYKN LKFQVWDLGGQTSIRPYWRCYFSNTDAIIYVVDSMDRDRIGISKQELVSMLEEDELKKAI LVVFANKQDIEGAMSVTEVANALGLSALKNRKYQIFKTSAIKGEGLDEAMEWLANSIQNT K----------------------------------------------------------- ---SRTYAAEGRFTFTSHTAGEHTICLLSNSTAWFGGGQLRVHLDIQVGEHANDYQQIAA KDKLTELQLRVRQLLDQVEQITKEQNYQRYREERFRQTSESTNQRVLWWSIAQTVILLVT GFWQMRHLKGFFEAKKLVMFYHVELEHEILLHPRYFGPSLLNTVKQKLFTEVEGTCTGKY GFVIAVTTIDNIGAGLIQAGRGFVVYPVKYRAIVFRPFKGEVLDAVVTQVNKVGLFTEIG PLSCFISRHSIPADMEFDPNSNPPCYKTKDEDMVIQEDDEIRIKIVGTRVDATDIFAIGS LMDDYLGLVSRLYSKAVFTGFKRGLRNQRENTALLKIEGVLNKNETDFYLGKRCAYVYKA KRKTACPGHDKSSRLRVIWGKVTRSHGNSGAVRAKFRKNLPATAMGKRIRVMLYMAKKTY DLLFKLLLIGDSGVGKTCLLFRFSDDAFNTTFISTIGIDFKIKTVELGGKKIKLQIWDTA GQERFHTITTSYYRGAMGIMLVYDITNAKTFDNISKWLRNIDEHANEDVEKMILGNKCDI EDKRQVSKDRGDTIAREHAIPFLETSAKSNINVENAFMDLAQAILNKMPQNEHIELHRKR YGYRLDYHERKRKKEARAGKELSKKSQKLRGIKAKLFHKKRHSEKVQMKKTIKMHEERQT KQKTDDKVPEGAVPAYLLDREGQSRAKVLSNMIKQKRKEKAGKWEVPIPKVKAMSEKDVF KVVKSGKTRRKGWKRMITKATFVGEGFTRKPPKFERFIRPMGL----------------- ------------------------------------------------------------ -------MAARPLISVYSEKGEPTGSSVTLPAVFRAPIRPDIVNFVHSEIRKNNRQPYAV SVGAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRR VNVNQKRYAMCSAIAATGIPSLVMSKGHRVEELAEVPLVIADKVEEVKKTKEAVAVLKRL KAWSDIEKVKNSRRQRAGQGKLRNRRRVQRRGPLVIYNQDNGICRAFRNIPGITLLNVSR LNLLKIAPGGHMGRFCIWTESAFKQLDSLYGTWRKASEKKADFNLPMTKMTNTDLARLLK SEEIQNAIRAPKKDRQRRVLKKNPLKNIRTMIRLNPYAAVQKRNAVQKKNKQKLLDQKRG IATVETKGKARPRKTTA-AGEQELGTKSLQIQSKRFFLDVKQNRRGRFIKIAEIGAGGKK NRLLLAMSTAAEFRNHLTEFSEHYASLGPPNPDNLPEDGKLKTEVMIKDNRRYYLDLKEN QRGRFLRVSLRSQQRTQIAIPAQGMIEFRDALTDLLDEFGTDDHEVHGDLP--------- -----------------------------------------------HDKKIRDAQMRAA INQKLMETGEKEKLKELLRMRLIECGWRDQLKAYCKDVVKKKGLEHITVDDLVAEITPKG RALIPDQVKKELLQRIRAFLAAQPNMNIRCAKPEDLMNMQHCNLLCLPENYQMKYYFYHG LSWPQLSYVAEDEKGKIVGYVLAKMEEDPEDSVPHGHITSLAVKRSHRRLGLAQKLMDQA SRAMVESFNAKYVSLHVRKSNRAALHLYANTLKFQISEIEPKYYADGEDAYAMRRNL--- ----MSHTILLVQPGRKPESRTYSDYESVNECLEGVCKIYEEYLKRMNPTSPSITYDISQ LFDFIDQLADLSCLVYQKTTQTYVPHNKEWIKEKIYELLRRQAGRMADEGADKKGEEPKK IVHTYPLVRHSDMNEEMRVEAMELAVTACEKFSNNNETAAKLIKEVMDKKFGASWHVVVG EGFGFEITHEVKNLLYMFFGGSQAIILWKCSMSHRKFSAPRHGSLGFLPKKRSRRHRGKA KSFPKDDPSKDIHLTAFIGYKAGMTHILREVDRPGSKVNKKEVVEGVTIVETPPMVVVGV IGYIETPKGMRSFKTIFAEHLSEECKRRFYKNWYRSKKKAFTKASKKWQDEQGKKEIEKD FAKMKKYCRVIRVIAHTQMKLLKKRQKKAHLMEIQINGGSITQKVDWAREHLEKHIPITQ VFGQDEMIDVIGVTRGRGYKGVTSRWHCKKLPRKTHKGLRKVACIGAWHPARVSYSVARG GQKGYHHRCEINKKIYRIGAGIHTKDGKVIKNNASTFYDLTDKTITPMGGFPHYGEVRND FLMIRGGLPGAKKRCLTLRKSLLTHTKRKAQEKITLKFIDTSSKWGHGRFQTPQEKSNFM GPLKKDMQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLG LWDTAGQEDYDRLRPLSYPQTDVFLICFSLISPASFENVRAKWYPEVSHHCPNTPIILVG TKLDLREDKETVEKLKEKKLSPITYPQGLAMAKEIAAVKYLECSALTQKGLKTVFDEAIR AVLCPKPKPKTKRPCLLLVFDPSLKKKKKKKTPFDLDAAMEDVSLEDNLTKKKKKKKKVF DMGDIEAAVPKEEASLLSKKKKSDTDRDYTYDELLKRVFDIMREKNPDMVAGEKKRFIMK PPQVMRVGTKKSSFSNFSDICKMLHRQPKHLLAFLLAELGTSGSIDGNNQLIIKGRFQQK QIELVLRRYIKEYVTCHTCRSPETILQKDTRLYFLQCETCGSRCSVASIKSGFQAVTGKR SAIRAKTTFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGK DYSIHRLILGTHTSDEQNHLLIASVQLPNDNAQIDASHYDSDKGEFGGFGSVSGKIEIEI KINHEGEVNRARFMPQNPCVIATKTPSSDVLVFDYTKHPSKPDPSGECQPELRLKGHQKE GYGLSWNPNLNGHLLSASDDHTICLWDINTTPKEGRVIDAHTIFTGHTSVVEDVSWHLLH ESLFGSVADDQKLMIWDTRSSNTSKPSHTVDAHTAEVNCLSFNPYSEFILATGSADKTVA LWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQSAEDA EDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEETDTPAS ELEMPAPSRARVYPDVNTQRPREYWDYESHLVEWGQQDDYQIVRKLGRGKYSEVFEAINI TNNDKCVIKILKPVKKKKIKREIKILENLRGGTNVITLLAIVKDPVSRTPALIFEHVNNT DFKQLYQTLGDYDIRYYMFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLA EFYHPGQEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPFFHGHDNY DQLVRIAKVLGTEELYAYIEKYQIDLDPKFNDILGRHSRKRWERFVHSENQHLVSAEALD FLDKLLRYDHAERLTAKEAMEHPYFYHVVKE-VPESLLKKRKKSAERHFEKRQLAFKRAE KYVKEYRIKERDEIRLHREARKHGNFYVPEQPKLALVMRIRGINGIHPRPRKVMQLLRLR QINNATFVKLNKATIHMLRIAEPYIAFGYPNLKTVRDMIYKRGFGKVEGRRVPLTDNAII EEKLGKFGIICVEDLIHEIFTVGPNFKQANNFLWHFKLNTPTGGXKKKGNHFVENGDYGN REDKINALLKRM------------------------------------------------ ----NMKLVFRRYATLYFIVGIDEEENELAVLEFVHNIVETLERYFEKVCELDIMFNLDK VHMILDEMIMNGRIIETNRSRIL------------------------MSKAHPPELKKYM DKRLVLKLNGARSVSGVLRGFDPFMNLVIDESIEETKSGEKRSVGMVVVRGNSIVLLECL ERIEFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTI RLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFQQTSKWIDDVRTERGTDVIIM LVGNKTDLSDKRQVSTEDGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMEQTE- ----------------------------------------------------KFIRDITR EVTGFAPYERRTLELLRISKDKRALKFCKKRLGTHLRGKRKREEMIRTIQQQRQSMVDEG TKRALAKIPLLKTKASPRDGELWVQRLKEEYQSLILYVGNNKEADNDWFRLESNKEGTRW FGRCWYIHELLKYEFEIEFDIPVTYPTTAPEIAIPELDGKTAKMYRGGKICLTDHFKPLW ARNVPKFGIAHAMALGLGPWLAVEIPDLIQKGVISHKELLDTVDFLDDVRRMNARQLYYQ VLNFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFFRGDLLFLTNYKEEPIRVGD IVVFKVEGREIPIVHRVLKVHEKLEGDVKFLTKGDNNQVDDRGLYAPGQLWLEKKDVVGR ARGFVPYVGIVTILMNDYPKCKYAILALLGLFVLIHREMSTMNPEYDYLFKLLLIGDSGV GKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYR GAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEY ADQLGIPFLETSAKNATNVEQAFMTMAAEIKNRMGPAPSPPNVKINASTPVKQGGGGCCE EALGEEVLRMGTDEIVSRTRLLDNEIKIMKSEVMRISHELQAQKEKIKENAEKIKVNKTL PYLVSNVIELLDVDPQDQAEEDGANVDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDPENL KPGDLVGVNKDSYLVLETLPAEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELIEAVVLP MTHKERFETLGIQPPKGVLLYGPPGTGKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGA KLVRDAFSLAKEKAPAIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFMPNSN IKVIAATNRVDILDPALLRSGRLDRKIEFPTPNEEARARIMQIHSRKMNVSADVNYDELA RCTDDFNGAMCKAVCVEAGMIALRRGATELSHEDYMDAILEVQSKKKANLNYYAKDAADQ NFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRQDKRVKLQIWD TAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDNAQVVLVGNKC DLEDERVVSTERGKQLADQLGLEFFETSAKENINVKAVFERLVDIICDKMSESLDSDPTQ TKRLTENPNPQNSGCQC------AITRDYISQPRLTYKTVSGVNGPLVILDGVKFPKFAE IVKLTLQDGSQRSGQVLEVSGSKAVVQVFEGTSGIDAKHTTCEFTGDILRIPVSEDMLGR VFNGSGKPVDKGPTVLAEDYLDIQGQPINPWSRIYPEEMIQTGISAIDGMNSIARGQKIP IFSAAGLPHNELAAQICRQAGLVKLPGKSVMDDHEDNFAIVFAAMGVNMETARFFKQDFE ENGSMENVCLFLNLANDPTIERIITPRIALTTAEFLAYQCEKHVLVILTDMSSYADALRE VSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLT GYITEGQIYVDRQLHNRQIFPPINVLPSLSRLMKSAIGEGMTREDHADVSNQLYACYAIG KDVQAMKAVVGEEALSQEDLLYLEFLQKFEKNFIAQGPYENRTIFETLDIGWQLLRIFPK EMLKRIPAEKLAKYYPRDA-GPGFVGIRFCQECNNMLYPKEDKETRTLMYACRNCEYSQV ADNPCIYVNKIEHEIDELTQIIADVIADPTLPRTEDHPCPRCNHKEAVFFQSQSNRA-EG MRLYYVCTQPNCAHRWTEKPAYKVADISLAEWGRKALDMAENEMPGLMMMRRVYGPKKPL KGARIAGCLHMTLQTAVLIETLTELGAEVTWSSCNIFSTHDHAAAAIAKTGVPVYAWKGE TDEEYLWCVEQTLVFPDGQPLNMILDDGGDLTNLVHTKYPQYLPGIKGLSEETTTGVHNL YKMMKKGELKVPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGKVAVVAGYGDV GKGSARALQAFGARVIVTEIDPINALQAAMEGFQVTTMDEACSQARVFVTATGCSGILEG KHFEQMPEDAIVCNIGHFDCEIDVKWLDDNCVSKDNVKPQVDRYTLKNGRHLILLAEGRL VNLGCAMGHPSFVMSNSFTNQVLAQIELWTKSSEYTTDVHILPKKLDEEVAAAHLEHLGV NLTKMTATQAEYLGIPQEGPYKPFHYRYADDSEQAPTPTVEEPLDLIRLSLDERIYVKMR NDRELRGRLHAYDQHLNMILGDVEETVTTVEIDEETYEEIYKATKRNVPMLFVRGDGVIL VSPPMRTMSTSNVENFSPQTIRQVAKELSGLVADPPEGIKVFPNENDITEVQATIEGPSG TPYTGGIFKMKLVLGKNYPNEPPKGFFLTKIFHPNVAKNGEICVNTLKKDWKAEMGIKHV LLTIKCLLIVPNPESALNEEAGKLLLEQYDDYSMRAKMYTEIHARP-------------- ----GLQVNPVRTIAAA--SGEIEFGSNKYFALCGFGGILSCGITHTAVVPLDLVKCRIQ VDPAKYGGIINGFRITVKEGGIKELGKGWAPTLIGYSMQGLCKFGFYEVFKNVYGNLLGE EKTFLWRTSLYLAASASAEFFADIALCPMEAVKVRIQTQPGWASSLREGVPKLIAEEGIG GFYKGIVPLWCRQIPYTMMKFACFERTVEALYKNVVPKPRAECTKGEQLIVTFVAGYIAG VFCAVVSHPADTIVSKLNKEKDATAMGVAKNLGWKGMWGGLGPRIIMIGTLTALQWFIYD TVKVAFGLPRPPPPEMPASLRAKLEHWKMERFATFALLPIIPAAFMFTLDYAVAAVVLHV HWALGGVATDYVHMSMAAFGGLCYLNYNDIGIVQAVIRFFSELNEAQEEDASELTFPTEF ENAETLLVSEVQRKQQNENAEEEQELSEVFMKTLNYTQRCSKFKNRETIAAVRSLLMQKK LHKFELAAIANLCPETADEAKALIPSLEGRFEEEELQQILDDIQTKRSFQYTKQPHLSKQ DLSCLEINKLTPLTPEVISRQATINIGTIGHVAHGKSTVVKGLSGVQTVRFKNELERNIT IKLGYANAKIYKCDSPTVPRPQCYTSRGSAHPDDFPCDVVGGGNFKLVRHVSFVDCPGHD ILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQ AKEQYDQILKFVQGTIAEGAPIIPISAQLKYNVDAVCEYLVKKIPIPVRDFTSEPKLIVI RSFDVNKPGCEVDELKGGVAGGSIIRGVLKVGQEIEVRPGIVSKDQEGKLTCRPIFSRIV SLFAEQNDLQYAVPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIYTELVISYFLLR RLLGVRTEGDKKAAKVQKLSKDEILMVNIGSLSSGGRVLAVKADLAKIGLTTPVCTEIGE KIALSRRVEKHWRLIGWGEIRKGVTIKPMAELLLDSNIRFWVFLPIVVITFLIGILRHYV TILLSSEKKVELQQIADSQALIRSRMLRENGRYIPHQAFQMRKDFLNNEESGYFTKNPMT DPSMMTDMMKGNITNVLPMIVIGGWINWAFSGFLTTKVPFPLTLRFKPMLQRGIELYSLD ASWVSSASWYFLNVFGLRSMYNLILGQDNAADQTKVMQDQMSGAAMAMPPDPSKAFKAEW EALAIVDHQWALDGVEDEV-MFLWDWFAGVLNFLGLYKKSGKLVFLGLDNAGKTTLLHML KDDRMAQHVPTLHPTSEELSMGGMRFTTFDLGGHQQARRVWKDYFPAVDGIVFLVDACDR DRFVEAKAELDSLLTDEQIASAPVLVLGNKIDVAGAASEDELRHLFGMHGQTTGKGTVPL SELRPMELFMCSVLKRQGYGEGFRWLAQYINLLRRNRAGTKAEQWSSWPDESFEEMDSTL AVQQFIQQAIRRDFSNIDEILTPPDSQDEGVWKYEHLRQFCMELNGLAVKLQSECNPETC TQMTATEQWIFLCAAHKTPKECPAMDYTRHTLDGAACLLNSNKYFPSRVSIKESSVAKLG SVCRRVYRIFSHAYFHHRTLFDEYENETALCRRFTTFVTKYNLMSTDNLIVPILED---- ------------------------------------------------------------ DPPPPEDDENKEKRTDDISSWDAEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMI KGKTPEEIRKTFNIKNDFTPAEEEQVRKENEWCEEKNKRLTKGGKKGSKKKIVDPFSKKD WYDVKAPSMFNIRQIGKTLVSRTQGTKIASDGLKGRVFEVSLADLQNDEVAFRKFKLVAE EVQGRNVLTNFHGMNLTTDKLRSMVKKWQTLIEANVDVRTTDGYLLRVFCIGFTKKRPNQ IKKTCYAQSTKIRAIRXKMVEIMAREVSSNDLKEIVNKLIPDAIGKDIEKACQGIFPLHD VYVRKVKILKKPKFDIGKLMDLHGEGS-------------------------MSASAVYI LDIKGKVLICRNYRGDIDMSVIDKFMPLMMESEEEGTMAPIIQHGNTTFVYIKYNNLHLV ATTQKNTNLVLVFTFLHKIVRVFCEYFKELEEESIRDNFVIIYELLDELMDFGYPQTTDS KILQEFITQEGHKLEVAPRPPMAVTNAVSWRSEGIKYRKNEVFLDVIESVNLLVSANGNV LRSEIVGAIKMRVYLSGMPELRLGLNDKVLFESTGKGKSKSVELEDVKFHQCVRLSRFEN DRTISFIPPDGEFELMSYRLNTHVKPLIWVESVIERHQHSRVEYMIKAKSQFKRRSTANN VEIVIPVPQDADSPKFKTTTGSCKYAPDQNAVIWTIKSFPGGKEYLMRAHFGLPSVEGED SEGRPPIHVKFEIPYFTVSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRTQ------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------DVLKPLQHKKLIEHELEGFGIRLNKEPPNISYKRKDKGG INLTMTVAQSELDLDLVKTILGEYRIHNADITIRFDASAEDLIDVIEGNRIYIPCIYVLN KIDQISIEELDVIYKIPHCVPISAHHKWNFDDLLEKMWEYLKLVRIYTKPKGQLPDYESP VVLKTDHVSVEDFCNKLHRSIIKEFKYALVWGSSVKHQPQKVGKEHVLQDEDVVQVVKKM AKHHPDLIFCRKQPGVAIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGSYQGRCVIC GGPGVSDAYYCKECTIMEKDRDGCPKIVNLGSAKTDLFYERKKYGFKKRPNLPPISAEKL AGKSMMRKVPVPSNRYTPLKENWMKIFTPVVEHLNLQIRFNLKTRNVEIKTCKDTKDIGA LQKATDFVRAFTLGFEVDDALALIRLDDLYLESFEITDVKPLKGDHLARAIGRIAGKGGK TKFTIENVTRCRIVLADTKIHILGSFLNMKTARTAICNLILGSPPSKVYGNMRAVAARSS E-RIKVAKPVVELDGDEMTRIIWANIKENLIFPYLDVDCLYYDLGLPHRDATDDQVTIDS AEAIKKHSVGIKCATITPDEERVEEFKLKKMWLSPNGTIRNILGGTVFREPILCAKVPRL VPGWTEPIVIGRHAFGDQYKATDFVVQGAGKFEMTFTPADGSEKRMEVFNFKD-GGVGMG MYNTDESITGFAHSCFQYALKKGWPLYMSTKNTILKRYDGRFKDIFEEIFQANYKKDFDA AGVWYEHRLIDDMVAQGLKSSGGFVWACKNYDGDVQSDIVAQGYGSLGLMTSVLMCPDGK TIEAEAAHGTVTRHYREHQKGNPTSTNPVASIFAWTRGLEHRANLDGTPEVAKFAQSLEQ ACVKTIDNGLMTKDLAGCIYGLKNVKKEHYLYTDDFLAAIRE---MGKLLSKIFGNKEMR ILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWR HYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMKPHEI QEKLGLTRIRDRNWYVQPSCATTGDGLYEGLTWLTSNAKSFGDLKTEASLKTLNEFLADK SYIEGYTPTAGDAVVFAALSKPGATLCHALRWYNHIKSYGNDSAKFPGAKKPVASYGPAG GADDDDDDDFDLFGDAAEKLKQKRIAEYTAKKSPTLIAKSSIILDVKPWDDETDMAEMEK LVRTISADGLVWGASKLVPVGYGIKKLQIICVVEDDKVGTDFLEEKITAFEDLVQSMDIA AFNKIKVQEVREVTRMERIGAHSHIRGLGLDDALEARNVSQGMVGQVTSRRAAGIILEMI KDGKIAGRAILIAGHPGTGKTAIAMGMAQALGQDTPFTSLAGSEIFSLEMSKTEALTQAF RKSIGVRIKEETEIIEGEVVEIQIDRPATGTGAKIGKLTLKTTEMETIYDLGQKMIESLT SEKVQAGDIITIDKATGKITKLGRSFTRARDYDAMGAQTKFVQCPEGELQKRKEVVHTVS LHEIDVINSRTQGFLALFSGDTGEIKTEVREQINSKVAEWREEGKAEIVPGVLFIDEVHM LDIECFSFLNRALETDMAPILIMATNRGITKIRGTTYASPHGIPIDLLDRLLIISTSPYE EKEIKQILQIRCEEEDVEISEDALTVLTRIGVETSLRYSIQLISTANLVSRKRKGTEVSV DDIKRVYSLFLDESRSTQFLKEYQQEFMFHEMAEFDLTTRMGQYLDRHLVLPLLEFSSVK EIYNEEEMLKGKLDLLSNTNMVDFAMDVHRLLYPDQDVPPMLKDKRSEVVSELKQIQAEV EPITKIFEDPKVKIETARDGKALFEFLVKNYDFRQDMVDILYRYAKFQYECGNYSGAAEY LYFVRVLVPAGDKNALNALWGKLASEILMQDWETALDDLNRLKEVIDNPLQSLQQRTWLI HWSLFVFFNHPKGRDLIIDLFLYQPQYLNAIQTMCPHILRYLTTAVITNKTVLKDLVKII QQESYMYRDPITEFLECLYVNFDFDGAQRKLRECETVLVNDFFLVACLDDFIENARLFIF ETFCRIHQCISINMLADKLNMSPDEAEKWIVNLIRNARLDAKIDSKLGHVVMGTQAVSPY YQVIEKTKQLGFKSQELVENIEKKLGQKQMGVDVETITPGDGSSFPAAGQKVEVHYTGTL TNGKKFDSSRDRGKPFQFTIGMGEVIKGWDEGVMKMSKGERAKLTCSPDYAYGASGVGGV IPPNATLLFDVELI---MPKYYCDYCDTYLTHDSPSVRKTHCNGRKHKENVRVYYQKWLE EQVQKLVDDTTAAFKADKPPRS----AGAAVPPPSGP-QPAPGPMMPMMGP-PGGHMGPM RPHMGPMGHMMPMMRPPEPLTLERDIQRAIELLEHLQRSGEVGKLAALQKVLQSEFCTAV REVYEHVYETVDISGSPEIRANATAKATVAAFAASEGHAHPRVVELPKTEEGLGFNVMGG KEQNSPIYISRIIPQGVADRHGGLKRGDQLLSVNGVSVEGEPHEKAVDLLKAAQGTVKLV VRYTPKVLEEMEARFDKQRTARRRQLACAVAVALSDPTVYFKEEFWESRWVSSTSKGAEQ GKFVLTAGKFYNDAEKDKGIQTSQDARFYGLSAKFDEAFSNEGKTLVVQFTVKHEQNIDC GGGYVKVFSSELDQAGMHGDSPYNIMFGPDICGPGTKKVHVIFNYKGKNLLTKKDIRCKD DVFSHLYTLIVRPDGTYEVKIDNKKVESGDLEADWDFLPPKMIKDPEAKKPDDWDDREKI DDPEDTKPEDWDKAEHIPDPDAKKPDDWDDEMDGEWEPPMIDNPEYKGEWKPRQVDNPNY KGKWVHPEIDNPEYVADDKLGVYEDFGAIGFDLWQVKSGTIFDNVLITDDEKAAEEHGEE TWGKAKDGEKKMKDAQDEEERKK---------------------MDAPMPEPSLYTVKAI LILDNDGNRLIAKYYDDTYPTVKDQRNLFNKTHRANAEIIMLEGLTCVYRSNVDLFFYVI GSQQENELILVSVLNCYYDAVSQMLKKNVEKRALLDNLDGVFLALDEVCDNGIIMESDAS TIVNRVSFRADDIPLGEQTVAQVLQSA----------MNVFRLCGDLSHLLAIVLLVLKI WKTRSCAGLSGKTQIMFALVYATRYLDLFTNFISLYNSSMKVIFIGTSFATVFLMFMKFR ATYDSNHDTFRMEFLLVPVAGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGE AETITSHYLFALGSYRALYIINWIYRYYFEGFFDLIAVVAGCVQTILYCDFFYLYITKVW KGKKLTLPAMKIEEVKSTTKTQRIATHSHVKGLGLDENGYAHQTAAGLVGQELAREAGGI ITEMIRAKKMAGRAVLLAGPPGTGKTAIALAIAQDLGNKVPFCPMVGSEVYSAEIKKTEV LMENFRRAIGLRIKETKEVYEGEVTELTPVETENPMGGYGKTVSHVVIGLKTAKGTKQLK LDPSIYESLQKEKVETGDVIYIEANSGAVKRQGRSDTFATEFDLEAEEYVPLPKGDVHKK KEVIQDVTLHDLDSANARPQGGQDIMSMMGQLMKPKKTEITDKLRKEINKVVNKYIDQGI AELVPGVLFIDEVHMLDIECFTYLHRALESTIAPIVIFATNRGKCTIRGT-DMTAPHGIP LDMLDRLMIIRTLPYSQEEMVQIIKIRAQTENLDIGDDALQLLSEIGVKTTLRYAVQLLS PASLVCKINGKESISVEEIEEINELFFDAKSSAKILAEQEDKYMKEFEVDEEGDQGLQKL KEKVKKRKGRGFPTRSGVEDYEGVETGGPGPQRSVEGWILFITNVHEEALEDDIIDKFAD HGDIKNLHLNLDRRTGFLKGYALVEYETFSEAQAAMENLNGSEILGQKINVDWCFVRGPS KTK-SYQLYRNTTLGHTLQESLDELISCSQITPQLALKVLLQFDKAINTALSNRVKNRIT FKGHLNTYRFCDNVWTFVLDNVDFRNVDKVKIVACDGKSTFLFTSESVGEGHPDKICDQI SDAVLDAHIKQDPNAKVACETAAKTGMIMLLGEISSKANVDYQKVVRDAIKHIGYDDSSK GFDYKTCNVLSALEEQSPDIAQGVHVGRNEEDIGAGDQGLMFGYATDETEECMPLTVVLA HKLNARLAELRRNGVFSWARPDTKTQVTIQYRMEKGACIPVRVHTVVISLQHSEDISTEQ LRKDVMEHVVNVVIPKKYMDAETVYHIQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAH GGGAFSGKDFSKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVAHPLSVFVSSYGT GVRSDQELLKIVNDNFDLRPGCIVRDLDLRKPIYQKTACYGHFGRPDFTWEQPKELKLMA GSALKRLMAEYKQLTLNPPEGIVAGPVHEENFFEWEALITGPEGTCFEGGVFPARLTFPA DYPLSPPKMKFTCDLFHPNIYADGRVCISILHAPGDDPMGYESSAERWSPVQSVEKILL- -------------------------------------------MRLEKCYFCSSTIYPGH GIQFVRNDCKTFRFCRSKCHKLFKRKRNPRKIRWTKAFRKSTGKDLTVDPSLEFEKRRHV PVKYDRQLWNKTVQAMKRVEEIKNKRQNLHILQRLKKGKELDKLADIAEYKKNIHLIKSP AASMAAYTIVMVRHGESSWNKENRFCGWFDADLAETGTNEAITAGKMLKDKGYTFDVAYT SVLKRAIKTLYHIQNELDLHWIPVTRHWRLNERMYGALQGLNKAETAAKHGEDQVKIWRR SFDTPPPAVEESDERWPGHDAKYKYVDKQLIPKAECLKDTI---------VIVPEIMKGQ RVLIAAHGNSLRSLVKYLDKMSDEEIMSLNIPTGIPLVYELDKDLKPIKHYYLADEAAVK AAMDKVAAQGKAKMEQEDILYNKPEYIETASGNKVSRQSVLCGSQNIVLNGKTIIVSDCI IRGDLANVRIGRHCVVSKRAVIRPPFKKFSKGVAFFPLHIGDHVFIGEDSIINAAQVGSY VHIGKNCVIGRRCVLKDCCAIADNTVLPPETVVPPFTLFSGSPGMSFFFGGRGNKTFKPK KNIPEGTHQYDLMKHAAATLGSGNLRLAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTVT EFCTEQSCPVMSAGPKYEYHWADGHTVKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKI GVPFPKNFLSIAKTILKRLFRVYAHIYHQHFDQVIQLQEEAHLNTSFKHFIFFVQEFQLV DKRELAPLQELIEKLSSKDMGIDIRHKYDRKVRRTAPKSEDVYLRLLVKLYRFLARRTSA KFNKIILKRLFMSKNNRPPMSVARVSRNMNKTGRSDKMAVIVGTVTDDIRMLKLPKLRIC ALHVTERARARILKAGGEIMTFDQLALKSPKGQNTVLMQGPRKAREAYRHFGLAPGVPHS KSAPYVRSKGRKFERARGRRASRGYK-DLKSENIQGSYDVARTVGLLRRIISQTRWANAG ELMAIIREEGTRLMDAQPSETAVGNMVRRVLKIVREEYIIEAINELISELETSGQALEHI HSNEVIRTVEAFLKKKFQVIVVEYQGHKLATSLAKAGIETTVITDSAVFAMMSRVNKVII GTHTLMANGGLKAIGSHSIALAAKHHSVPFIVCAAMFKLSPQYLTTHDDGFNKFVSPHDV HSPVFDYVPPDLVTLFISNIGGNAPSYVYRLLSELYHMIIPIRCFTCGKVIGNKWETYLG LLQAEYTEGDALDALGLKRYCCRRMLLSHVDLIEKLLNYAPLEKKSPDPVDGRKHMDVQT ELYLEELSDRMEEADVECQTDAFLDRPPSPLFIPAKTGVDVYTEILEGDLFDFDVEVKPI LEVLTGKTVEQALLEVMEEEELANLRSQQRAFEELRNAELVEQQRLEEQERRHREEKERR MKQQREILRKEKETAEKIAARAFAQSYLSDLVPSVFGTLSDNGYFFDPVERDVEQNFMPW LMGEVETRLDRVVAGRAVLDGLLRVVVNQRREAFAKMKASGVLREYKVIGRECPTEKVPV PPMYQMTIFAPNQATAKSRFWYFAGLLKKMKKSRGEIVCCSQVHDKSPTRIKNFAIWLRY VSRSGTINMYREYRDLTTCKAITQCYRDMGARHRARASSIHIIKVEVIPANQCRRVHVKQ FHDSKIRFPQPRRVAKRLHYPRFTTARPQTHY---------------------------- --------------LGLALYSASIGMAVAPGDFSIYLDYLKALELGPAFWFPIKIFCSFP IFYHCMSGMRHLYWDFKGGYEIREQNKSAYLILSSAPY---SIALSQYRDQHFKGSRIDQ DRLLHVTSTLYVGNMSFYTTEEQVYDLFGRCGDVKRIVMGLDKFKKTPCGFCFVEYYSRE DGESAMRYVNGTRLDDRIIRTDWDAGFKEGRQYGRGKTGGQVRDEYRTDFDSGRGGYGKI MATKVKPNYTLKFTLAGHTKAVSSVKFSPNGEWLASSAADKLIKIWGAYDGKFEKTISGH KLGISDVAWSTDSKLLVSASDDKTLKIWDVATGKCMKTLKGHSNYVFCCNFNPQSNLIVS GSFDESVRTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG KWIVSGSEDNTVFIWNLQTKEVVQKLQGHTDVVLCCACHPTENIIASAALEDDKTIKLWR SDVMIIYKDLFSEDELCSDTYPGVIICVKGKDGANFGANASSGVDVVLAKKKDYLTHIKG YIARVLEFQFFMGMIPLKYSTPYLYFFKHGLIEEKV--------------------TYIA NRVTDKLTKVTDQIYCCRSGSAADTQAIADIVNYYLNFHKMEMEQEPLVKTSAAIFQDLC YSYRDQLSAGIICAGWDRKKGGQVYSVPLGGMCVRQPFTIGGSGSTYCYGYCDATFKEGM TKEECLNFCKNTLALAMSRDGSSGGIARLAVITETGVERHIVLHDDLPKF---------- ---------------------------------VQLLGASYKEKVQPDLDELEVNMEDNE DAESTKSEVKLGKLQFSLDYDFQKGELTVGVIQAADLPGMDMSGTSDPYVKVYLMPDKKK KHETKVHRKTLNPVFNESFTFKVQYAEIGSKTLTFLIYDFDRFSKHDQIGQVQVPLNSVD LGRVVEEWRDLTSPEADNEKEDKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSD YKMKL-----------------------------------NELAKKTLEITVWDHDLGKQ NDYIGGVQLGINGKGERLRHWFNTLKTPDHIYEQWHTL-------MVLADLGRKITNALR SLGSATVINEEVLNSMLNEICRALLEADVKFTLVKKLRENVRSVIDFDEMAAGLNKRRMI QSAVVKELTKLIDPGVKAWTPVKGKSNVIMFVGLQGSGKTTTCTKLAYYYQRKGWKSCLV CADTFRAGAFDQIKQNATKARIPFYGFMTKGNEQESVARLKRLMTIMDS----------- ----------------------NDSELDSHE--GAKLFSRGRVARVARGAGVSQKDVQEL LTQKFAQMVKKMGGIKGLFK-GGDMAKNVSAQISKLNHQMAKMMDPRVLHQMGGMAGLQN MMRQFQQGAMSIMSYNGAAIIAMKGKNCVAIASDRRYGVQAQTVGMDFQKIFEMGPRLYV GLPGLATDVQTVHERLRFRLNLYELKENRRIKPKTFVSMVSNLLYERRFGPYFVEPVIAG LHPKTMEPYVASLDLIGCPMVTEDFVVSGTCTEQMYGMCESLWEPDLEPDDLFETISQAL MNALDRDAVSGWGAIVHIIEKDKVTTRTLKARMDMTSKDYYFDSYAHFGIHEEMLKDEVR TLTYRNSIYMNKHLFKGKVVLDVGCGTGILCMFAAKAGAKKVIGIECSSIIENAEKIVKS NKLDHIVTLVRGKVEEVALPDGIEKVDIIISEWMGYCLFYESMLNTVIHARDKWLAPGGL IFPDRATLYIAAIEDRQYKDEKINWWDSVYGFDMSCIRKVAISEPLVDVVDPKQIVSNAC LLKEVDIYTVKEDDLTFTVPFHLKCLRSDYIQAFITYFDISFTMCHKRTGFSTGPESRYT HWKQTDDYMTVKAGEDIDGVMTIKPNASNKRDLDFTIDVDFRGELSQMKESNEYKMRMVR EGKTAWKAKYFEKIVELFDENPKCFIVGVDNVGSKQMQTIRSSLRVLMGKNTMMRKALRG HLEKNPAIEKILPHLKGNVGLVFTKGDLTEIRDKINENKVAAPAKAGAVAPVDVSIPPQN TGLGPEKTSFFQALSIPTKISKGTIEILSSVLMVTAGDRVGASQATLLNMLKISPFSYGL IVVQVYDSGTIFSPEVLDITDDDLCARFMQGV-NIAAVSLAIGYPTLASAPHSIVNGFKN LLAI----------------SAAKGRLMAVIGDEDTCTGFLLGGIGELNKHRNPNFFVVD KNTSVSELEEHFKNFVNRDDIAIVLINQNIAEMIRHTIDMYDKPIPAVLEIPSKDHPYDA SKDSILRRAKGMFNPDECRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXMTFLTSWEEFSKAAEKLYIADPMNCRFVIKYRHCSGKLVIKMTDDTVCLQYQ TEHAQDVKKLEKLTSQLMRHMASKELYEEVKLYRNAREREKYDNMADLYAVINTLQCLEK AYIKDLVTPKEYTAACSKLLVQYKAAFKQVEGDEYRTVEIFMKKCKLDCPAALERIKEDR PITIKDDQGNTSKCIADIVSLFITIMDKLRLEIRAMDEIHPDLRELMETMNRLSLLPREY EGKTKVSTWLQTLGGMQASDELDDAQVRQMLFDLESAYNEFNRVLHN------------- ----------------------ALVDHLNAGVAQAYVNQKKLDTETKILQANAAQFSKQT MQWLRLVEDFNQSLKEIGDVENWARSIETDMRTISSALEYAYK----------------- ------------------------------------------------------------ ------------------------------------------------------------ ---FDQKKETYSVDEQRKTDQVNVDKQILDAIRKHAEKKLVFGYLGSMFALKSKQYPHQM VFLDFLFGRKKTPQEMLRQNQRALNKAMRDLDRERQHMEQQEKKIIADIKKMAKAGQMDA VKIMAKDLVRTRRYVKKFILMKANIQAVSLKIQTLKSNDAMAQAMKGVTKAMTTMNKQLK LPQIQKIMMDFEKQSEIMEMKEEMMNDAIDDAMGDEDDEDESDAIVSQVLDELGLQMTDK LSDIPNTGVS-GKQAVGVSDADADLEARLDNLRRQNNYCDFCLGDESENKKTGQKEELVS CADCGRSGHPSCLQFTANMIISVKKYPWQCIECK-------------LLFCDDCDRGYHM YCLNPPLSEPPEGSWSCHLCIKEFYG--ERSVNLYPLTNYSFGTKEALYEKDPSVAARFK RMREEFEKLGMRRSVEGVLIVHEHGLPHVLLLQLGTTFFKLPGGELNPTEDPVQGLKRLL TETLGRHDGPPMDWLIEDTIGNWWRPNFEPPQYPYIPAHITKPKEHKRLYLVQLPEKAQF AVPRNYKLVAAPLFELYDNASGYGPIISSLPQALSRF-----FTPSGTTPTGQKAMAMAT PTPGHLMSMTPEQMQAFTLKREIDERNRPLTDDELDTMFPPGYKVLQPPAGYVPIRTPAR KLTATPTPMAATPTGFRMQVSVVDMQPKGNLPLLKPDDMQYFDRKIMKLLLKIKNGTPPM RKAALRQITDKAREFGAGPLFNQILPLLMSPTLEDQERHLLVKVIDRILYKLDDLVRPYV HKILVVIEPLLIDEDYYARVEGREIISNLAKAAGLATMISTMRPDIDNMDEYVRNTTARA FAVVASALGIPSLLPFLKAVCRSKKSWQARHTGIKIVQQIAILMGCAILPHLKNLVEIIE HGLVDEQQKVRTITALALAALAEAATPYGIESFDSVLKPLWRGIRQHRGKGLAAFLKAIG YLIPLMDAEYANYYTREVMLILVREFQSPDEEMKKIVLKVVKQCCATDGVEPQYIKEEIL PPFFKHFWNQRMAMDRRNYRQLVDTTVEIANKVGAAEIVSRVVDDLKDEAEQYRKMVMET IEKIMGNLGSADIDSRLEEQLIDGILYAFQEQTTEDVVMLNGFGTVVNALGKRVKPYLPQ ICGTILWRLNNKSAKVRQQAADLISRIAIVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLG SILGALKSIVNVIGMTKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGAEFVS AREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVC TTVAIAIVAETCSPFTVLPALMNEYRVPELNVQNGVLKSLSFMFEYIGEMGKDYIYAITP LLEDALMDRDLVHRQTAMAAIQHMALGVYGFGCEDSLTHLLNYVWPNIFETSPHVVQAFM GAIEGVRVGLGAAKILQYTLQGLFHPARKVRDVYWKVYNTVYIGAQDAMIPAYPRIMNDD KNQCIRYELDYMLDDFMCDDEEYDLEYSEDSNSEPDVDLENQYYNSKALKEDDPKEALNS FQKVLELEGKDKGEWGFKALKQMIKINFKLGNFTEMMTRYKQLLLYIKSAVTRNYSEKSI NSILDYISTSKQMELLQNFYETTLEALREAKNDRLWFKTNTKLGKLYFDREEYVKLQKIL KQLHQSCQTDEGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPL IMGVIRECGGKMHLREGEYEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGIN PFDSQEAKPYKNDPEILAMTNLVSAYQNDDINEFETILKTNRQNIMEDPFIREHIEDLLR NIRTQVLIKLIRPYTQIHIPFISKELNIDVTEVENLLVSCILDNTIHGRIDQVNSVLELN AGVARYSALDKWTSQLMSLHQSVVNKMA-------------------------------- ----------------------------------------------------------EK DMHYYQSCLEAILQNSPEAKVFCLVHKMDLVQEDQRDHIFREREEDLKRLSKPLATSIWD ETLYKAWSSIVYQLIPNVQALENNLTHFAKIIDADEVLLFERATFLVIAHCQHMQHRDVH RFEKISNIIK-FKLSCSKLAAAFQSMEVRNSSFAAFIDVFTSNTYVMVIMSDPSIPSAAT LINIKNARKHFEKLERLGAVLSFSTRLFSVLRFESVIHEFDPYFNYRTTKFLVEEGFYNF HNWFDDRAWYPLGRIIGGTIYPGLMVTSAAFYHVLNFLNITIDIRNVCVFLAPVFSSLTV LITFVLTKELKDAGAGLVAAAMISIVPGYISRSVAGSYDNEGIAIFCMLFTYAMWIKSVK TGSVFWASICALAYFYMVSSWGGYVFLINLIPLHVIALMVTGRFSHRIYVAYNTVYCLGT LLSMQISFVGFQPVQSSEHMAAFGVFGLCQIHAFIDYVRSKLSYHQFQLLFRSLVLFTGV IIATATGKISPWTGRFYSLLDPSYAKNNIPIIASVSEHQPTTWSSFYFDLQMLVFMFPAG LYFCFKELTDANIFIIMYGITSIYFAGVMVRLMLVLAPVMCILSGISVSATLNTYMKNLD MGRKAETNYPIKNEIASAVVFLVTVFLITYTFHCTWVTSEAYSSPSIVLSARAGDGGRII FDDFREAYYWLRHNTPEDAKVMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMAS TEDKAYEIMRELDVDYVLVIFGGLTGYSSDDINKFLWMVRIGGSTDRGAHIKENDYYTPQ GEFRIDKEGAPTLLNCLMYKMCYYRFGSVYTEGGKPTGYDRVRNAEIGNKDFELDVLEEA YTTEHWLVRIYKVKDLENRGNQLNIRPLQRLVCARFFGEFTGFVGMCVQHIPSPQANAHN KVETIYTGPTDTELAEAMFQCDPDGPLMVHTTKLYPTTDATAFHVLGRVVSGTLYANQDV RILGENFSLQDEEDSRHGQCGRLWISEGRYTVEVNRVPAGNWVLIEGVDQPIVKTATITE ASGNEEAHIFRPLKFNTSSVMKIACEPVNPSELPKMLDGLRKINKSYPLITTKVEESGEH VVLGTGELYLDCVMHDLRKMYSEIDIKVADPVVSFCETVVETSSLKCFAETPNKKNKITM IAEPLEKGLAEDIENEVVQITWPRKRLGEFFQNKYDWDLLAARSIWAFGPDSTGPNILVD DTLPSEVDKGLLGSVKDSIIQGFQWGTREGPLCDEPIRNVKFKILDAVIAAEPIHRGGGQ VIPTARRVAYSAFLLATPRLMEPYYFVEVQAPADCVSAVYTVLARRRGHVTQDAPVPGSP LYTIKAFIPAIDSFGFETDLRTHTQGQAFCLSVFHHWQIVPGDPLDKTIVIRPLEPQPAT HLAREFMIKTRRRKGLSEDVSINKFFDDPMLLELAKQDVMLSYPMQETFMLFDSKGDGKI SGRQLGDVLRAMGQNPTEAEVKKCNDSDMRISFEMFLPVLQTVSKNKDTNTIEDFIEGFR VFDKEQNGTISSAELRHLLTSLGEKLLDEEVEQLLMGQDDAQGNVNYEEFVKTVISGMSE LTFNIDNGYLEGLVRGFKGGVLKQADYLNLVQCETLEDLKLHLQSTDYGNFLANEASPLA VSVIDDKLKEKMVVEFQHIRNQAVPPLSTFLDYITYSYMIDNIILLITGTLHQRAISELI PKCHPLGSFEQMEAIHIASTPAELYNAVLVDTPLAAYFIDCISEQDLDEMNIEIIRNTLY KAYLEDFYQFCSRLGGATANVMCEALAFEADRRAFIITINSFGTELTKDDRSKLYPRCGQ LHPDGLS------------AVAEYYTEYRVLFEGSGTNPGEKTLEDKFFEHEVHLMKNAF LQQFHFGVFYAYIKLKEQECRNIIWISECVAQRHRAKIDSYIPIFSCRKTTRHIPQVPER ILDAPEILDDYYLNLIDWSAQNLLAVCLAGHVYLWDASTGDIQQLMEMENPEDYVTSVSW IKEGNYLAVGTSSSEVQLWDVTSQKRIRCMTGHSARVGALSWNNHILSSGSRSGMIHHHD VRQAQHQV-AEAAGHTQEVCGLRWSPDGRFLASGGNDNLLQVWQEQAGQPLYTFSQHQAA VKALAWCPWQPSLLASGGGTADRHIRFWNCNTGTCVSSVDTKSQVCALLWSKEYKELISS HGFAHNQLVIWKYPGMTKVSELTGHTARVLHMAKSPDGSTIVSAAADETLRLWKCFS--- ------------------IFVGLYYCLTDQGYRFDFGWFLSQTSPYLWANMGIGLSISLS VVGAAWGIYTTGSSILGGGVKAPRIRTKNLVSIIFCEAVAIYGIIMAIVISNAMNAKAGY MMFGAGLTVGLCNLFCGICVGIVGSGAALADAQNGALFVKILIIEIFGSAIGLFGVIVGI LQSTGAKMGNKMAATRRLAKELSDNT-EDNVLQWTCLIKPSDIPYNKGAFKIRIDFPAEY PFKPPKITFQTKIYHPNIDEKGQVCLPIISAENWKPATKTDQVLEALVRLVKTPEPEHPL RADLAEEFSRDKKRFFKNAEDFTKRYAEKR---GASLSYPNQCSALRKNGYVLIKGRPCK IVEMTTSKTGKHGHAKVHMVGLDIFTGKKYEDICPSTHNMDVPHVYRDEFDIIDVSDGFL TLMNKEGTLREDLLITAYVIKSMGEERVTKIET--------------------------- ------------------------------------ITVSDTNNDCVQIFDDGNFIHQFG RTGTGKGELRQPFGVAADKE-HILVVDSGNKRVQVFTKDGQFVSMVELEQPRGMAIT--- ------------------MAAGPIAERNQDATVYVGGLDEKVSEAILWELFLQSGPVVNV HMPKDRITQSHQGYGFVEFMGEEDADYAIKIMNMIKLYGKPIRVNKASAHQKNLDVGANI FIGNLDPEVDEKMLYDIFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFEAADAAIESM NGQYLCNRPISISYAFKKDSKGERHGTPAERLLAAQNPLSQADRPHQLFADTPPAPAPGS VAPPPPPPSSLT------GMPPLGVPPPPMPPPPGF---------------PPPPGMGGM PPRPPPPSAPPPPM------KAEPKKVVNPLFEKRPKNFGIGQDIQPKRDLSRFVKWPKY IRLQRQKTILFKRLKVPPSINQF------------------------------------- ------------------------------------------------------------ ------------------------EGGGALSKLVEAVKTNYNERYDEIRRHWGGGV---- -------------------MRYVAAYLLAVLGGNNSPSAADVKKILSSVGIDADDSCVKT VIDQLKGKNIEEVMAEGRTKLASMPSGGGGAA-------------------VVIKKIHAR QIFDSRGNPTVEVDLTTDKGLFRAAVPSGASTGIYEALEMRDGG-KTYHGKGVMNAVGNV NNVIAPALVLDIADQAAIDKIMLDMDATENKAKFGANAILGVSLAVCKAAAAHKGVPLYQ HIADLAGNKQLIMPVPAFNVINGGTHAGNKLAMQEFMILPTGASSFSEAMRMGTEIYHHL KKVIQKKYGQDACNVGDEGGFAPNILDNFEGLELLKVAIENAGYTGKIEIGMDVAASEFC KKYDLDFKNPKSDPATWLTPDQLFDVYKGFCEKYPVTSIEDAFDQDDWAAWTKMNAIQLV GDDLLVTNPKRVKDGIEKKACN-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------GVHDMLEHGGSKILPVIPQLIIPIKYALSTRKQQVMCTTLKVLQHLVVS ADMVGEALVPYYRQILPVLNIFKNKNLNSGDGIDYSQQKRENIGDLIQETLEAFERHGGD DAFINIKYMVPTYESCMMNAPPTFDSFLLYEGEKKVVIEKDTKVPNAAVFTVNKEDHTLG NMIRTQLLKDPQVLFAGYKNPHPLEFKITIRIQTTSDYTPQEAFTNAITDLIAEVSLLEE RFREAIREKE---EDHRRKWDREEYEKLARERLEKETGKKEPPVKRELLKPREYKVDLDS KLGKSQVITKTTPAAQQGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSSLD QVKKRFEMNKKKKEETKKDYDFEERMKELREEEEKQKVYRREKRKERKRKATDDEMDPDM AAIMGFSGFGTSKKMGCAVSSEDKQAMERSKQIDKSLRADGEKASREVKLLLLGAGESGK STIVKQMKIIHEKGYSNDECLQYRPVVYSNTIQSMIAIIRAMGQLKIDFGHPDRADDARQ LFSLAGGAEDGE-MTPELAAIMKRLWKDSGVQECLGRSREYQLNDSAEYYLNALDRISMP SYM--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------EIKSEADRTLIYITL YVTECLKKLQKCQSKNQGLKEMHTLAITRFYIPGEGAFPLNALYHRPASRPEEDTMRAYF TQLRQETGIRVVEKIFDPATDKPSKWWMCFVKRKFMDKSLSAPGQAGPYNYSYIFKYIII GDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVAGQKIKLQIWDTAGQERFRAVT RSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIFLIGNKSDLEAQRDVTYE EAKQFAEENGLMFLECSAKTGENVEDAFLDTAKKIYQNIQDGSLDLNAAESGVQHKPSTP RNALNTDQSQNKEGCACMSIKSVCVMASGAVKGTINFEQQGAVKVTGEITGLAAGEHGFH IHEFGDNTNGCTSAGSHFNPEGKTHGGPSDAVRHVGDLGNVTAGKFTIEDKLISLTGPHS IIGRTVVVHEGVDDLGKGG-----------------------MVNFTIDEIREVMDHKTN IRNMSVIAHVDHGKSTLTDSLVSKAGIIAGSKAGETRFTDTRKDEQERCITIKSTAISLY YQLKKADANPGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQA IAERIKPILFMNKMDLALLTLKLDKETMYQTFQRIVESVNVIIATYGDEDGPMGDISVAP DKGTVGFGSGLHGWAFTLKQFAEIYSDKFKIETPKLMKRLWGDQFFSMARGFCKFILDPI FQMFDLCMSKEDVMKLVEKLAVKLTSEEKDLDAKPLLKCIMRHWLPAGDTLLQMICLHLP SPVTAQRYRVEMLYEGPNDDDAANAIRTCDPKGPVMMYVSKMVPTNDKGRFYAFGRVFAG TVASGLKCRIMGPNFVPVKSIQRTILMMGRYTEPIEDVPCGNICGLVGVDQFLVKTGTIT TFEKAHNMRVMKFSVSPVVRVAVECKNPADLPKLVEGLKRLA------------------ --------------------------------------------------NKHNRIFMRC QPMPDGLPEDIEKGEVTPRQEMKERARYLSEKYDYDATEARKIWCFGPEGTGANIVVDCS KGVQYLNEIKDSVVAGFQWATKEGVLADENMRGVRFDIHDVTLHADAIHRGGGQIIPTAR RVLYASVISAGPRLLEPVYLVEIQCPENAIGGIYGVLNRRRGHVFEEGAVAGTPMFIVKA YLPVNESFGFTADLRSNTGGQAFPQCIFDHWQIMIVMETRKRKGLKLELPALDHFNDKLM LPLSLLRTAVNHPMLVELKNGETYNGHLVSCDNWMNINLREVICTSRDGDRFWRMPECYI RGSTIKYLRIPDEVIDMVKEEVVQKSKGRGDMRRGGRGGPGRGSFGQRGGR-GGPGRGGG PG---------------------------------------------------------- ----------------------------------------------------GSWDSTVR LWDPRTPCSAGTFTQPDKVYTLALYGDKLVVGTAGRRILVWDLRNMGYVHQRRESSLKYQ TRCIRCFPNKQGYVLCSIEGRVAVEYLDPAPEVQKKKYAFKCHRLKEDGVEKIYPVNAIS FHNVHNTFATGGSDGFVNIWDGFHKKRLCQFHRYPTSISSLSFSHDGSMLAIA------- --------------------MDFQHRAGGKTGTGGVSSASETNRDRRERLRQLALETIDI NKDPYFMRNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQANLARRAAKEAKEAPAQPAPE KARVDIRKFVKIGRPGYKVTKQRDPETGQQSLLYQIDYPEIVEGVMPRHRFMAAYEQKVE PPDKKWQYLLFAAEPYETIAFKVPSREVDKDPKKFWTHWNKETKQFFLQFAFKHDPK--- ------------------------------------------------------------ ----------------NDDPTDQMFVFFPDEPKVGIKTIKTYCQRMQEENISRAIIVVQT GMTPSAKQSLADMAPKYILEQFLEAELLINITEHHLVPDHELMTPDEKKELLERYK---- --------DPVARYFGLKRGQVVKIIRPSETAGRYISYRLVV------------------ ------------------------------------------------------------ ----------------------------------------APEEVSAMVLVKMKETAEAY LGKEVTHAVVTVPAYFNDAQRQATKDAGSIAGLNVMRIINEPTAAAIAYGLDKRDGEKNI LVFDLGGGTFDVSLLTIDNGVFEVVSTNGDTHLGGEDFDQRVMEHFIKLYKKKKGKDIRK SNRAVQKLRREVEKAKRTLSSQHQARIEIESLFDGEDFSETLTRAKFEELNMDLFRSTMK PVQKVMEDSDLAKTDIDDIVLVGGSTRIPKIQKLLQDFFNGKEPNRGINPDEAVAYGAAV QAGVLSGEEETGDLVLLDVNPLTMGIETVGGVMTKLIQRNTVIPTKKSQIFSTAADNQPT VTIQVFEGERPMTKDNHLLGKFDLTGIPPAPRGVPQIEVSFEIDVNGILKVSAEDKGTGN KEKITINNDQNRLSPEDIERMIQDAEKFADDDKKVKERVEARNELEGYAYSLKNQIGDKE KLGAKLSDEDKETIEKAVEEQITWLEAHQEAESEEFKAHKKELEDIVQPIMTKLY--TPP PGSEEDHDELDEAVDDTELEAIKARVKEMEEEAEKLKEMQSEVEKQMSVEEKIDADARSI YCGNVDYGSTAEELEAHFHGCGSINRVTILCDKFTGHPKGFAYIEFADKDSVATAQALDD SLFRGRQIKVSAKRTNRPGISTTNRPPRGRFRRPRSNYGGGGYQPR--RGGRFRSRRSSW YSPY------------------------------------------RKRVKMLQRQLLEV RKEKEQELQQRNEAIAHLKDQLQETKAKTNMEGKYIKKSCEVMVAQTQKRCGMQEKDMKE EIEQLRHKVDEETRVNAEIESYLRTHQTELEQKVDYWMDKYEKDVEKKQRELDVLKASKA KDLERLQELTKLYAEYENVVLEDRIEKEKNRRKAEQEAEELRAAVRIQSWFRGVMVRRGL GAFGKKKKGKPKVGINGFGRIGRLVLRAALKQVNVVAVNDPFIDLDYMVYMFKYDSTHGR YKGDVSLVVDGQSISVYNMMKPSEIPWGTAGAEYVVESTGVFTTIEKANAHIQGGAKKVI ISAPSADAPMFVMGVNHEKYEKSMNIISNASCTTNCLAPVAKVIHDNFGMIEGLMTTIHA YTATQKVVDGPSSKAWRDGRTAAQNIIPASTGAAKAVGKVIPDLNGKLTGMAFRVPVTNV SVVDLTCRLEKDATMDQIKAAVKGAMKGFLGYTEDAVVSTDFISDEHSSIFDAGACIALS PKFVKLVSWYDNEFGYSNRVVDLIKHAYKVDQEDLATAILRRKERPNRLCVEEAVNEDNS VVSLSQAKMDELQLFRGDTVLLKGKRRRETVCIVLSDDTVTNDKIRINRCVRNNLRVRLG DIVSIQACPDVKYGKRVHVLPIDDTVEGLTGNLFEVYLKPYFMEAYRPVRKGDIFLVRGG MRGVEFKVIETDPSPYCIVAPDTVIHCEGEPVKREEEEEALNEVGYDDIGGCRKQLAQIK EMVELPLRHPQLFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSK LAGESESNLRKAFEEAEKNSPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQ RAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEILRIHTKNMKLADDVDLE RVAAETHGHVGADLAALCSEAALQQIREKMDLIDLEDEQIDAEVLDSLAVTQENFRWALG KSNPSALRETSVEVPNVSWEDIGGLENVKKELQELVQYPVEHPDKFLKFGMTPSKGVLFY GPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFD ELDSIAKARGGNAGDGGGAADRVINQLLTEMDGMSSKKNVFIIGATNRPDIIDPAILRPG RLDQLIYIPLPDEKSRINILKASMRKSPVSKDVDLEYLSKVTHGFSGADLTEICQRACKM AIRECIEQEIRREREQAEKADDYDPVPEIRRDHFEESMKFARRSVSDNDIRKYEMFAQTL QQSRGFGGGNTSTFGTSSVFGSNSNYNAMKDYEVTSPPDDSVSSLAFSPGILPSTFLIAG SWDNNVRCWEVQQNGQTIPKAQQTHTGPVLGVCWSDDGTKVFTASCDKSAKMWDLNSNQA VQVAQHDAPIKTVHWVKAPNYSCLMTGSWDKTLKFWDTRTPNPMMTIQLPERAYCADVQY PMAVVGTAGRGLSIYQLENQPQEFKHIESPLKYQHRCVSIFADKKNSSPGGFALGSIEGR VAIHYVNPQNPKDNFTFKCHRNGVQDIYAVNDIAFHPVHGTLATAGSDGRFSFWDKDART KLKTSEQFDQPISTCCFNAQGSIFAYASSYDWSKGHEGFDPQKMKPHIFLRSCYDELKPS QKK------GKRRMDTDVVKLIESKHEVTILGGLNEFIVKFYGPQGTPYEGGVWKVRVDL PEKYPFKSPSIGFMNRVFHPNIDEVSGTVCLDVINQAWTALYDLSNIFESFLPQLLTYPN PIDPLNGDVA-----------------------------------------------MDD QDIITTLKILIIGESGVGKSSLLLRFTDDTFDPEQSATIGVDFKVKTITVDGNKAKLAIW DTAGQERFRTLTPSYYRGAQGVILVYDVCSKSSFSRLGQWLNELETFSTKHDIVKMLVGN KIDMERREVTRDEGLKFARKHHMLFIEASAKTKEGVQCAFEELVEKIIQTPGLWETDGLS LGSVIWGVINKGFCSFKVKTKTQKFCRNEFSLTGLCNRSSCPLANSQYATVREEKGVIYL YMKTIERAAFPRRLWEKVKLSRNFETALKQIDDQLIYWPHFLKQKCKQRFTKITQYLIRM RRLRLKRQKKLVPLQRRVERRENRREEKALVAAQLENAIEKELLERLKKGTYQDIYNFPT TAFDKALEQEEVGDEQETDNEIEYVAEEEFDESDISDMELIQGRFQTEPRLKTFKIYRWD PERAGDKPRMHAYEVDLNTCGPMVLDALIKIKNEIDPTLTFRRSCREGICGSCSMSVGGK NTLACLCKIDANTSKTTKIYPLPHMYVVKDLVVDMNNFYAQYKRIEPYLKKKDVKEEDIG KEAFHQSPEDRAKLDGMYECILCACCSTSCPSYWWNQDKYLGPAVIMQA----------- -------------------------------------------------------DIKPN HTIYINNLNEKIKKDELKRSLYAIFSQFGQIVDIVALKTLKMRGQAFVIFKDVTSATNAL RSMQGFPFYDKPMRISYSKKDSDVIAKMKGTFVERPKKKRSEGSKKKKKTAAPTSIPEQP PHHILFLTNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENEVQAGAAKDALQ GFKITPTNAMKISFAKKMDSQGRKVVICDNGTGFVKCGYAGSNFPTHIFPSLVGRPLLRS NTKVGDIEIKDLMIGDEASALRSMLEVNYPMENGIVRSWEDMIHLYDYTFGEQKLNIDPR ECKMLLTEPPMNPTKNREKMIEVMFEHYQFDGLYVAIQAVLTLYAQGLLTGVVIDSGDGV THICPVYEGFALPHLTRRLDIAGRSVTRYLIKLLLLRGYSFNHSADFETVRIMKEKLCYV GYDVEQEQKLALETTVLVESYTLPDGRVIKVGGERFEAPEALFQPHLINVEGVGVAELLF NTIQAADIDTRPEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDSEKLNKFKIR IEDPPRRKHMVFLGGAVLADIMKDKDSFWMTRAEYEEKGLRVMEKL---MADTVGKPITC QAAVAWEAKKPLSIETVEVAPPKAHEVRIKLLATGVCHTDAYTLDGFDSEGKFPVILGHE GGGIVESVGEGVTNVAPGDHVIPLYIPECGDCKFCKSPKTNLCSKIRSTQGSGVMPDGTS RFTCKGQTIYHFMGCSSFSEYTVVADISVAKVDEKAPLEKVCLLGCGISTGYGAALNTAK VEPGSTCAVWGLGAVGLAVLMGCKKAGASRIIGIDINPDKFETAKKFGMTEGVNPKDHSR PIQEVLVEMTDGGLDYTFECVGNVATMRSALEACHKGWGTSVIIGVAAAGTEISTRPFQL VTGRTWKGTAFGGWKSVSSVPKLVDSYMQKDLMVDEFITHNMGLTDINKAFDLMHAGESM ESYDVIANQPVVIDNGSGVIKAGFAGDQVPKYHFPNFIGRPKHVRVMAGALEGDMFIGPK AEEHRGLLTIKYPMEHGVVRDWNDMERIWQYIYSKDQLQTFAEEHPVLLTEAPLNPRRNR EKAAEIFFETFNVPALFISMQAVLSLYATGRTTGIVLDSGDGVTHTVPIYEGFAMPHSIM RVDIAGRDVTRYLQLLLRKEGHNFHTSAEMEIVKTIKERACYLSINPQKEETMETEKTQY TLPDGSLLEIGPSRFRAPELLFRPDLIGEECEGIHEVLSYAIQKSDMDLRRVLFSNIVLS GGSTLFKGFGDRLLSEVKKLAPKDIKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKR EYDEEGVRAVHRKTFKTNQISNVIVHPLVLLSVVDHFNRMGKVGNVKRVVGVLLGSNRQG VLDVSNSFAVPFDEDDKDKSVWFLDHDYLECMYTMFKKVNAREKIVGWYHTGPKLHQNDV LINELIRKYCPNSVLVIIDAKPKDLGLPTEAYIAVEEVHDDGTPTTKTFEHVPSEIGAEE AEEVGVEHLLRDIKDTTVGTLSQRITNQLLGIKGLHSQLGDIHSYLEKVSSGKLPINHTI VYQLQDIFNLLPDMHFQEFIKSVYMKTNDQMLVVYLASLIRSIIVLHNLINNKLQNRDAE KNEGKKDDMGLLFSKLWGLFTNEEHKVIIVGLDNAGKTTILYQFLMNEVVHTSPTIGSNV EEVIWKNIHFLMWDIGGQESLRSAWSTYYTNAEFVILVVDSTDRERLSITKEELYKMLNC EDLKKAAVLIFANKQDIKGAMSSAEISQQLNLTSIKDHGWHIQACCALTGEGLYQGLEWI TSHIRRRAIPTKRITVNDPSQLPHDYSTTPGGTLFSTTPGGTRIIYDRSFLMQCRNSPLA KSPP-NLPKIPGVTSP-------------------------------------------- ------------------------------------------------------------ -LNNNKNSDFCAPLTSFDWNEVDPNLLGTSSIDTTCTIWGLETGQVMGLVSGHVKTQLIA HDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLAWNKQ DP---------------------------------------------------------- --------------------------------------------------RNLSTTSKVA VLGASGGIGQPMALLLKTNPAISHLSLYDIVHTPGVAADLSHCSTPAKVTGHQGPEELGD CLKDCDVVVIPAGVPRKPGMTRDDLFNTNASIVKTLAEGCAIHCPKAMICIVSNPVNSTV PIASEVFKKHNVYDPRRIFGVSTLDIVRANTFISEAKGLNVASVNCPVIGGHSGVTIIPL ISQCTPPVSFPEDERAKLIVRIQEAGTEVVQAKAGAGSATLSMAFAGAKFVNSVLDALNG EIGVVECTFIKSEETESKYFSTPVLLGKNGVEKNLGLGKLMEHEVALLKKAMPELLTNIQ KGEDFVHKNIDRGKDFNIKTRIITDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFAS TLSHLRRLNSPVGRDGKLARPRQLHNTLWGMICPAETPEGGAVGLVKNLALMAYISVGSQ PSPILEFLEEWSMENLEEIAPSAIADATKIFVNGCWVGIHRDPEQLMNTLKKLRRQMDII VSEVSMVRDIRDREIRIYTDAGRICRPLLIVENQKLLMKRRHIDLLKEREYNNYSWQDLV ASGVVEYVDTMEEECIMVAMTLEDLQDKSVVYCSTYTHCEIHPAMILGVCASIIPFPDHN QSPRNTYQSAMGKQAMGVYITNFHVRMDS------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------LCVEAPGGFSFENCHRNRFLEKGY KAPTAYKTGTTIVGIIFKDGVVLGADTRATEDTIVADKNCSKIHYIAPNIYCCGAGTAAD TEMTTNMISSQIELHRLHTGRTPRVCTANRMLKQRLFRYKGHISAALVLGGVDSTGPHLY SVYPHGSTDCLPYVTMGSGSLAAMAVFEDGWKPEMELEEAKELVARAIRAGIFNDLGSGS NVDVCVITKKVDYIRPYDEANLKGVRQGKYRYKKGTSAVLTESIKKLEFDVTMSKVTFKI VLTSDPKLPYKVLSVPEGTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPAQTAGNVFL KHGSELRLIPRDRVGHMAFTFAAFCYILALILSAFLIFFVIYHIIAFDELKTDYKNPIDQ CNSLNPLVLPEYGLHIFYNILFIFAGQWFTLLLNVPLIAYHIHRYMHRPVMSGNGLYDPT TIMNADQLSRAQKEGWVKLAFYLLSFFYYLYSMIYVLVSSMGLYTILKKMKEKEKEVRLL MLGLDNAGKTTILKKFNGEDINTISPTLGFNIKTLEHRGFKLNVWDVGGQKSLRSYWRNY FEMTDGLVWVVDSADRRRLQDCREELAALLLEERLAGATLLVFANKQDLPGALKAEEIKE ALDLQSITTHHWMIIGCSAVTGENLLSGIDWVIDDIASRIFTMD--KRKVCYYYDGDIGN YYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATQEEMTKFHSDDYIKFLRSIRP DNMSEYNKQMQRFNVGEDCPVFDGLYEFCQLSTGGSVAGSVKLNKQATDIAVNWAGGLHH AKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY GEYFPGTGDLRDIGAGKGKYYAVNFPLRDGIDDESYEHIFQPLLSKVMEVYQPSAIVLQC GADSLSGDRLGCFNLSLKGHGRCVEFMKKYNLPLLMLGGGGYTIRSVARCWTYETSVALG VEIANELPYNDYFEYYGPDFKLHISPSNMANQNASDYLDKIKTRLFENLRMLPHAPGVQM ADIPEDAINFEQNPDERISIRASDKRIACDEEFSDSEDE----------------DTKNF ECNICLDTARDAVVSMCGHLFCWPCLHQWLETRPQRQVCPVCKAAISREKVIPLYGRGST GQQDPRDKMPPRPPGQRTEPENNTGFPGFGFGFQMSFGIGAFPFGFFASTFNFNDGRPQP AAPGTPHHADEQFLSRVFLWVAVLFIFWLLIAMFAVVAKQEQAHEDSIWSVAWAKSERDG TEHIVTGSVDDTVKLWKWADLEHKHTLEGHALGVVSVDINSQGTMAASSSLDAHIRLWDL EAGKQVKSIDAGPVDAWTICFSPEARYLASGSHTGKINLFGVESGKQEHQLDTRGKFTLS LAYSPDGKYIACGAIDGIINIFDMTTGKLLEGHAMPIRGLCFSPDSQLLVTASDDSHIKI YDVQHANLAGTLS----------------------------------------------- ------------------------------------------------------------ -------------------------------------KCGPKVGEIWPYVEGEIKPTLEE LGILTPEQMGYDKPELAQEDVYDMVVRIRGLPWSASVDEVSNFLEGCEIVDGKDGINFTS TRDGRPSGEAYIELVTEKDLELALSKDKNHMGKRYIEVFRSKRSEMDWVVKRSGPGQDAV IRLRGLPFGCSKEEIAHFFSGMELVPNGITLLQDHQGRTTGDAYVQFASQEIAEKAQQKH KEKIGHRYIEIFKSSLEEVRNNYDSQTGHCIHMRGLPFVANEQDILDFFKPLNPVNVVLH YNDGRASGGADVDFATHEEAQSGMTKDRACMKHRYIELFYKDKEKPTQVRYSNITAAKAV ADAIRTSLGPRGMDKMIMSSKGDVTITNDGATILKEMQVLHPAAKMLVELSKAQDIEAGD GTTTVVVVAGSLLDAAQKLLAKGIHPTTISESFQRAAKKSMEILEGMSVPLELSDRASLL KSATTSLNSKVVSQYSSSLSPLCVDAVLSIIDPATATTCDLRDIRMIKKLGGTVEDTELV EGLVLNQKTAGTGGPHRVEKAKIGLIQFCISPPKTDMENQVVVTDYTQMDRVLKEERAYL LNIVKQVKKAGCNVLLIQKSILRDGVSDLALHFLAKMKIMVIKDIEREEVEFIC------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------MILLEINNRIIEDSLTVKFQGALAGAKLDAVDITAADFDGVLYHI SNPDGDKSKIRVSISLKFWQELQEHGADDLMKREYGDFLTATEADYNVSLVYDENVPSNW EAVVKKAGLLKRNCFASVFEKYFEFQEKHKRAVIHYRDEETLYVDARKDRVTCIFSTVFK DDDDIIIGKVFMQEFAEGRRRYQQAPQVLFSHKEPPLELSKTDAAVGDNIGYITFVLFPR HDAKDNTINLIHTLRDYLHYHIKCSKAYIHSRMRAKTSDLLKVLNRARPDTKSTEKKTIM LMFCPICANILIVEEGQRCFRFACNTCPYIHNVTRKISNRKYPKLKEVDDVLGGTAAWEN VDSTKEKCPKCEHERAFFMQIQTRSADEPMTTFYKCCDPSCGHRWR-------------- ------------------------------------------------------------ ------------------------------------------------------------ -----NMQVAINEAYKAGFLGKNACGSGYDFDVYMHRGAGAYVCGEETSLIESLEGKAGK PRLKPPFPADVGVFGCPTTVNNVETIAVAPTILRRGADWFAGMGRERNRSVMMDFDDLVA NQTALGTAAVIVMNKQADVVKCISRLMDFYHHESCGQCTPCREGITWLAKIMHRMVTGNA RPAEIDQMYELSKQVEGHTICALGDGAAWPVQGLVRHFRPELEARMKAYVEKHYTQEQVD EMNQQLNQTRGQRVRAAMFPETLEEGIQIPSTQIHPDQPTAVQRLAEPSQMLKHAVVNLI NYQDDADLATRAIPELTKLLNDEDQVVVSQAAMMVHQLSKKEASRHAIMNSPQMVAALVR AMSNTNDIETTRCAAGTLHNLSHHKQGLLAIFKSGGIPALVKLLSSPVESVLFYAVTTLH NLLLHQEGSKMAVRLAGGLQKIVSLLQRNNVKFLAIATDCLQILAYGNQESKLIILASGG PGELVRIMRSYTYEKLLWTTSRVLKVLSVCSSNKPAIVESGGMQALAMHLGHQSQRLVQN CLWTLRNLSDAATKQEGMEGMLQMLVQVLNSNDINIVTCAAGILSNLTCNNQRNKVTVCQ VGGIEGLVRTILQAGDREDITEPAVCALRHLTSRHPEAEMAQNAVRLHYGLPVLVKLIHP PSRWPLIKAVVGLIRNLALCPANHAPLREHGAIPRIVQLLIRAHQDTQRQQSAYVDGVRM EEIVEGTVGALHILAREAHNRAVIRGLNCIPLFVQLLYSPIENIQRVAAGVLCELAAEKE GAEVIEQEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKK-------------- -XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXX-------------------------------------WAYAYFRAMANNETPP VKERLEMPVATQKTDTGLTPGLLRVLNKQLGPKKVVPLSLIEEKWKDLALPKEQFDELVR IGTFSGDVEWIKFFALACSTLGESITDAMRTICEILTADPEGGPARIPFPLFQDLYKYLA QVDGEISQEHINSVISHLQYDVDKQDGLVQPRNFLGTDCPNLS-------RDQLMDQVKA QIAVANAQELLQKMSDKCFKKCVTKPGTSLDSSETKCIAMCMDRYMDSWNLVSRAYTTRL QKERTKMMNRLFGRGKPKGPAPNLNDCIQNVDSRGESIDKKISRLDQELAKYKDQMKKMR DGPSKNMVKQKAMRVLKQKKMYENQREGLANQSFNMEQSNFAIQTLKDTKTTVDAMKVGV KQFKKEYKNINIDKIEDLQDELEDMTEQAGEIQEIMGRSYGMPEIDDDELEAELDALGDD LMMDEDSSYLDQAPSIPEGSVSAPGA---STKDGVLVDEFGLPQIHAQMTPMTPATPETP QLQNIVCTVNLNCKLDLKKIALHARNAEYNPKRFAAVIMRIRDPRTTALIFGSGKMVCTG AKSEDLAKLAARKYARIVQKLGFNAKFMDFKIQNMVGSCDVKFPIRLEGLVLTHGQFSSY EPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKVRQEIYEAFENIYPILKGFKKQQDDDE DEFVGMEMEAEGGSRHDEEDFPFQVLTTEEIVQHMVDCIKDVNAVVEIPATTTRILLNHF KWDKEKLMEIYYDGDQDKLFSEAHVISPFKKALEATCDICFMSYPSAMTGLECNHPFCIR CWTEYLTTKIMDEGMGQTISCAAHGCDILVDDATVMKLVTDPKVKLKYQHLITNSFVECN RLLRWCPMPDCGHAVKVTYHDARPVTCACDHIFCFACGENWHDPVRCKWLRKWIKKCDDD SETSNWIAANTKECPKCQIIIEKDGGCNHMVCQTCKADFCWVCLGPWEPHGSSWYNCNRY DEDDAKKARDAQERSRSALQRYLFYCNRYMNHMQSLKFEHKLYASIKTKMEEMQQHNMSW IEVQFLKKAVDVLCQCRQTLMYTYVFAFYLKKNNQSIIFEDNQKDVENATEQLSEYLERD ITSDMLVDIKQKVQDKYRYCESRRKVLLDHVHEGYEKELWDYQDMASTDGKLSTTDRVVK SVPFPPSHRLTMSEVFDAKGKPRPDVLKQHFILEGRVTEDVALRLINDGAALLRQEKTMI DIEAPVTVCGDIHGQFYDLMKLFEVGGPPATTRYLFLGDYVDRGYFSITERVYDSCMEAF DCLPLAALMNQQFLCVHGGLSPEIHNLEDIRKLDRFKEPPAFGPMCDLLWSDPLEDFGNE KTTEHFTHNSVRGCSYFYSYSACCDFLQQNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSL ITIFSAPNYLDVYNNKAAILKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVT EMLVNVLSICSDDELMTEGD---------------------------------------- ------------------------------------------------------------ -----------------------GGGRGGRGGMRGGKAVTVEPHRHLGVFIARGKEDALC TKNMVPGEAVYGEKRIPIEEGVKIEYRAWNPFRSKLAAAILGGVDNIHMKPGSKVLYLGA ASGTTVSHVSDLVGPDGLVYAVEFSHRSGRDLINVAKKRTNIIPIIEDARHPHKYRMLVG MVDTIFADVAQPDQARIVAINAHNFLKNSGNVVISIKASCIDSTAQPEAVFAAEVNKLRE EKIKPQEQITLEPYERDHAVVVGTYRAPKK-MDPKNLKDIAGRLQKGGKGAGLGLGLLAA AGGAIYGLAQSMYTVEGGHRAIIFNRIGGVSQNIYKEGLHFRVPWFQYPIIYDIRSRPRK VSSPTGSKDLQIVNIALRVLSRPDPGTLPFIYQTLGTDYDDRVLPSICNEVLKSVVAKFN ASQLITQRQQVSLMVRKELTDRARDFNIILDDVAITELAFGKEYTQAVEAKQVAQQEAQR ATFVVEKAKQERQQKVVQAEGEAEAAKLIGVAVSQNPGYLKLRKIRASQSVARTIATSKN RVYLTAGSLILNVNDPAYDEGLESYTGSSSDEEDINPREKDQKNSNGFKDFCVRIEQNAF GRREIEIAEQEMPGLMALRKRAQGDKPLSGAKIVGCTHITAQTAVLIETLGALGGQVRWA ACNIYSTQNEVAAALAEAGFSIFAWKGESEDDFWWCIEKTIQADNWQPNMILDDGGDATH LMLRKYPNMFARVKGIVEESVTGVHRLYQLSKSAKLTVPAMNVNDSVTKTKFDNLYSCRE SILDALKRTTDVMFGGKQVIVCGYGEVGKGCCEALKGMGSVVMVTEIDPICALQACMDGF RVVKLNEVIRQVDIVITCTGNKNVVSREHLEKMKNGTIVCNMGHSNTEIDVNGLRTKDLT WERVRSQVDHIIWPDGKRIILLAEGRLVNLSCSSIPSFVVSITAATQALALIELYNAPAG RYKHDVYLLPKKMDEYVASLHLPSFDAHLTELTDEQAKYLGLNKAGPFKPNYYRY-DPDA IKMFVGQIPRSMDENDLRKMFEEFGPVYQLNVLRDKVTGQSKGCCFVTFYTRKSALDAQN MMHNIKTMPGMQHPIQMKPADSEKRNVEERKLFIGMLSKKCTENDVRMIFAPFGTIEECT VLREQNGQSKGCAFITYASRQCALNSIKAMHHSQTMEGCRSPLVVKFADTQKEKEMKKVQ Q---------------------------------------------CLRHTLQQEGVRGL YHGAAPAVKAAVVFCSYGVCEELVRMTGVVASFFLCPMELVKCRLQALAREVLRAEGVRG LYRGLNGIWVKEIPGSFIYFGSYETAKSAMVTLNP-DHKHSNELFSCGVFAGLC-YCVTH PVESVKTRVQVRNEGFRPLCNGLRPTMLR--------------------DSSNEFVRLSQ AVGNNIQKVTQNVAQMQRMVNQIGTSQDTPQLRDKLHQVQHYTNQVAKETTNYLRDLMRH QSEQRQRKMQRDRLTGEFTSALNNFQAAQRQAAEKEKASVQDVDLQLIQQREQDIRKLES DIVDVNQIFKDLGMLVHEQGEVIDSIEANVESVHVSDGAQQLHMAKDYQSKARRKKCIII IIILVVLAIIGLIIGLTVNMVNVSKGILVECDPAMKQFLLHLDETNALGKKFVIKDLDET HIFISGDILDTLQDKIDGLMDKLNFPIGKGKQKTPTPQEAIQRLREIEEMLQKKSDFLEG KVANELATAKKRAALQALKRKKRYEKQLQQIDGTLSTIEFQREALENASTNTEVLNVMGE AAKALKAAHKNMNVDDVHELMDDVAEQQEIANEISDAISNPVGFGDGIDEDELNAELEEL EQEELDEQILQI-DLPSVPSSEDDDLRELEMWASSMQRFHNRVRQILMASGSTTFTKIVN KWNTALIGLMTYFREAVVNTQELLDLLVKCENKIQTRIKIGLNSKMPSRFPPVVFYTPKE LGGLGMLSMGHVLIPQSDLRWSKQTDVGITHFRSGMSHDEDQLIPNLYRYIMPWESEFID SQRVWAEYALRTDMIQALGGVEGILEHTLFKGTYFPTWEGLFWEKASGFEESMKYKKLTN ASKDQMDGTTTQKYWLDIQLRWGDYDSHDIERYARAKFLDYTTDNMSIYPSPTGVLIAVD LAYNLHSAFGNWFPGCKPLIQQAMAKIMKANPALYVLRERIRKGLQLYSSEPTEPYLSSQ NYGELFSNQIIWFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSV WAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKG SELQLPFQACLKVEKFGDLILKATEPQMVLFNLYDDWLKTISSYTAFSRLILILRALHVN NDRTKIILKPDKTTITEPYHIWPTLTDEEWMKVEMQLKDLILADYGKKNNVNVASLTQSE IRDIILGMEISAPSAQRQQIAEIEKQTKEQSQMTATTTRTVNKHGDEIITTTLSNYESQT FASKTEWRVRAISATNLHLRTNHIYVSSDDIKETGYTYILPKNILKKFITISDLRAQIAG FLYGVSPPDNPQVKEIRCIVMCPQWGTHQTVHLP-VLPNNEYLKEMEPLGWIHTQPNELP QLSPQDVTTHAKVMADNASWDGEKTVIITCSFTPGSCSLTAYKLTPSGFDWGRQNTDKGN NPKGYLPSHYEKVQMLLSDRFLGFFMVPSQGSWNYNFMGVRHDPNMKYELQLSNPKEFYH EVHRPSHFLTFSAIEDGTDREDLY--YTASRPNLAINKHTKVICQGFTGKQGTFHSQQAI EYGTNMVGGVSPGKGGKTHLDLPVFNSVKEARDATNCDATVIYVPPKFAAPAILEAIDAE VPLIVAITEGIPQQDMVKVKHKLLRQGKSRLIGPNCPGIIKPGECKIGIMPGHIHKQGKI GIVSRSGTLTYEAVYQTTQVALGQTLCVGIGGDPFNGTNFIDCLEVFLNDPETEGIVLIG EIGGQAEEKAAAYLMEHNTSKFKPVASFIAGLTAPPGRRMGHAGAIIAGGKGGANEKIQA LKDAGVEVTLSPAQMGTAILEAMKKAGK---ESLKCTLCQERLEDTHFVQCPSVSDHKFC FPCSRDSIKRQGAGA--------KCPLVGSNVPWAFMQGEIATILGFSRFVEVGRVAWVA FGADKGKIVAIVDIIDQSRVLVDGP-KNVPRCCKSLKQLHLTNIVAFPASARTGVVRKAW EKAEVDKVFGESTWAKKIAAREKRAAMSDFDRFKLMKAKQSRNRIIASRCGTLAKTNKKT CPLLLRVFCCMGRHHVLSEYSRGNTPANELQIYTWMDATLKELTSLVKEVNVDARKKGTF FDFAIVYPEPRTPVCRVREIGSTCSGRKGADDNVTLASKRFDIGDYIDIAIQPPRGLGKT LQTISLLGYMKHYRNIPSPHLVIGPKSTLANWMAEIKRWVPSLRAVCLIGSQAERAALIR DVLMPGEWDICVSSYEMVIKEKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKTANR LLLTGTPLQNNLHELWALLNFLLPDVFNSSEDFDSWFNSSNIAENDQLVTRLHEVLRPFL LRRIKKDVEKSLPPKQETKVFVGLSKMQREWYTKLLLKDIDVVNGAGKSDKLRLLNILMQ LRKCCNHPYLFDGAEPGPPYTTDKHLVDNSGKMYVLDKLLPKFLAEGSRVLIFSQMTRVL DILEDYCCWKEYDYCRLDGQTAHTDRQTQIDEYNRPGSNKFVFMLSTRAGGLGINLMTAN IVILFDSDWNPQVDLQAMDRAHRIGQKKVVRVFRFVVENTVEERIMERAEMKLRLDNVVI QQGRLVDAQT-KDVLQMIRHGANHVFASKDSELTEVDIDAILKRGEEKTEQLNKKMEELG ESTLRTFTLDTPESSVYQFEGQDYRDKHKIPGIGNWIEPPKRERKANYAVDAYFREALRV SEPKAPKAPRPPKQPSVQDFQFYPPRLFELLDQEIYYYRKTIGYRVPKNPDLGSDAERVR KEEQRKIDESDILSQEELTEKEDLLKGFTNWNKRDFNQFIKANEKYGRDDIEGISKEVEG KSPDDVMEYSSVFWERCNELQDIERIMAQIERGEAKIQRRIGIKKALDAKMARYRAPFHQ LRIQYGTNKGKNYTEEEDRFLVCMLHKLGFDRENVYDELRTSVRQAPQFRFDWFIKSRTA MELQRRCNTLITLIERENMELEEREKAEKKKDTKHSWADQIELGEE-GLESPREEFDAKN GIKTITEYKHNDDGKKVKVVSTYKIETRRLAKSASARKLWKKFGAAASDGPGPNPANTIE DVHMQFMSPKDMADDSVFGKLKVSCRYCKGDHWSKQCPHKDKLEAITEAIAKPGKYVPPS LRDGARRPGESMQSDESATIRVTNLSEDTRESDLQELFRPFGSIQRIYLAKDKVTQQSKG FAFINYHRREDAARAIAGVSGFGYDHLILNVEWAKPS----------------------- --------------NHNIGVEFGSKVVNVGGKSVKLQIWDTAGQERFRSVTRSYYRGAAG ALLVYDITSRETYNALTNWLTDARTLASPNIVIILVGNKKDLEAEREVTFLEASRFAQEN ELMFLETSALTGENVEETFLRCARCILTKIESGDLDPERMGSGIQYGDASLRRLQQRRPE CSC-IQSSSKPTLDTSQWPLLLKNFDKLNVRTAHYTPIASGCSPLKRPIVDYVKSGFINL DKPANPSSHEVVAWIKRILRVEKTGHSGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYV CIFRLHSAVDNEKKVLQAVDTLTGALFQRPPLIAAVKRQLRVRTIYESKMMEYNKENNMG IIWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGIQSEKDSLMTMHDVLDAQWQFD HNKDESYLRRVIKPLEALLTSHKRVILKDSAVNAVCYGAKIMLPGVLRYDDGIEVGDEIV IVTTKGEGVALAIAQMTTAVIATCDHGIVAKIKRVIMERDTYPRKWGLGPMASKKKAMIK DGTLDKHGKPNSTTPKDWTSSYVDYAKPKKRKHDTPSKEDKKKKKKKK------ERKRAP GKGQARSSQAVNAAQRTGADIDTSKKYAAGQNKQHSANKNTAKLDRETDELHHSTISLDV SKLIQQGRQAKGFTQKDLSTRINEKPQIVNDYEAGRAIPNQ------------------- -------MLKPKALTQALSQANTGGVQSTLLLNNEGSLLAFSGYGDKDARVTAAITSNIW SAYEKNGKSAFNEDQLNFVLMECEEGVVAITRVANLLLCMYAKETVGFGMLRAKAQSLAD YLEGPLTQVATSSSATARIQSKKQTLDDAYAPPANFLEIDVVNPQGKKRYTDYEVRMRTN LPVFKVKESSVRRRYSDFDWLKGELERDSKIVVPSLPGKAWGRQLPFRNDDGLYEEQFVE DRRKGLEQFVNKVAGHPLAQNERCLHMFLQEPVIDKNYVPGK------------------ -----------------------------------RDIATKGSREVKGKTHTYYQVLIDG RDIPHIRVGTESVTFLSSQENGTLYSIPGLDYIGHEDVLPYTTTEKQPIHNHLFDKFIGQ ESPYVARDTLREWQDKNHPWLELTDVHRETTENIRVTVMPFFIGEVQQTHVYWWRYCIRL ENLGEETVQLRERHWRIFSLSGTLETVRGRGIIGKEPVFSKLQPAFQYTSHVSLQAPSGH MWGTFKMEREDGPSFECRIPPFSLESK----MATSKGANTYNRQNWEDSEFPVLCQTCLG DNPYIRMTKEKYGKECKICVRPFTVFRWCPGARMRFKKTEVCQTCSKLKNICQTCLLDLE YGLPVQVRDAALKIQDEMPKSDVNKEYYTQNMEREIANSDGTVSVGALGKAMAPSDMLLK LARTTPYYKRNRPHICSFWVKGECKRGEECPYRHEKPTDPDDPLADQNIKDRYYGLNDPV AEKLLNRYQNMPKLDPPEDMDVFLMIRRRKTTTFIDAKESTTVIELKKMLQGITKKPPED NRLYKDNKTLGDYGFTSSTARAQAPATIGLVFREFEPLEIAPLSTPPELPDVMRPQESSS SHVQEHALRYEAVVMRSRFDEHKDEDMVKAKQLLQAGEQELFEKMHPQPFKFANSPGGVA YGREAKIPDWMFDVWHPLERAQYPEYFARREQRKQEYIDKWHQKYGK------------- ------------------------------------------------------------ --------------------------------------------ILFCHQRRVLHRDLKP QNLLIDSKGVIKLADFGLARAFGIPVRVYTHEVVTLWYRAPEVLLGSPRYSTPVDVWSIG CIFAEMVTKRPLFHGDSEIDQLFRIFRTMTTPTEENWPGVSSLPDYKPIFPNWKTNTLSQ SVDAVGVDLLQKTLIYDPSARMTAKDALQHPYFAARLFNALGKLGVGLAVAGGVAQSALY NVDGGHRAVIFDRFAGVKPGVIGEGTHFLIPWVQKPIIFDIRSRPRSVPTVTGSKDLQNV NITLRIIFRPLATELPNIYTNLGIDYDDRVLPSIVNEVLKAVVAQFDASELITQREVVSQ KVSEELTLRTTQFGMVLDDIAITHLTFGREFTHAVEMKQVAQQDAERARFVVEREEQRKK AAVIRAEGDAIASELLSDAFRVAGEGLVELRKIEASEDIAYQ------------------ ---MKVINSQQTIKLDPAVDISVKARVVTVKGPRGVLKRDFRHLTVDIKKVGKSSICVEK WFGLRKELATVRTVCTHIQNMVKGVTKGYKYKMRSVYAHFPINVALSEAGTVVEVRN--- --------------------QKDELVIEGNDIELVSRSAALIQQSTTV------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFIVAMSE YDLTLAEDQEMNRMMESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSALNVCFPE YTGANTYEEAAAYIQLQFNKRRETKEIYTHFTCACDTNNVQFVFDAVTDVIIKNNLKDCG LFKKFAVMKRMINLKDSRIDKKDRLSKKRKKADPQNMKIRELPKVSSALFLKYNTQLGPP YHVLIDTNFINFSIKNKLDILKSMMDCLYAKCTPYITDCVMAELEKLGSKYRVALRIAKD PRFERLPCLHKGTYADDCLVKRVTEHKCYIVATCDKDLKRRIRKIPGVPIMYLSEHKYSI ERMPDAFGAPK------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----KGNYILSAGVDKTTIIWDASSGHCTQQFAFHSAPALDVDWQSNVSFASCSTDQCI HVCKLGTDKPIKTFQGHTNEVNAIKWDPQGSLLASCSDDMTLKIWSMKQDSCVHDLQAHS KEIYTIKWSPTGPGTNNPNAPLILASASFDSTVRLWDVERGLCIHTLTRHQEPVYSVAFS PDGKYLASGSFDKCVHIWNVQSGSLVHSYKGTGGIFEVCWNHRGDKVGASASDGSVFVLD LRKTGNDLASLFECPVCFDYALPPIMQCQSGHIVCSACRGKLTLCPTCRGPLGNIRNLAM EKVASTVMFPCKYSSSG------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -LMTIVVNLVFLGQAFTIMLVYVWSRRNPYVRMNFFGLMNFQAPFLPWVLLGFSLLLGNS VIVDLMGIAIGHIYYFLENVFPEQPGGFKILRTPSILKWLLDPHTEDPDYNPLPPGGFDW G-GVELLSDQGFRADGRRSTELRKIQCRLGVFAQADGSAYIEQGNTRVLAAVYGPHEVRG SKGKHDAAIINCQYSQATFSTGERKRRPRGDRKATEMTQHLEQTFQAAIQTSLYPRSQID IFVEVLQSDGGNYCASVNAATLAVVDAGIPMRDYVSACSASFVDDTPIVDVNYVEESSGP ELLVAMLPKTEQIVFLQMNARVHEDHLSKVLDTATKGCKDVYAIIDRSVRDMAGNYYFAI IGHHDNPVFEMEFVPPNKTNEPKKDDHRHLNQFIAHASLDLVDEHMWATSNMYLKIVDKF NEWFVSAFLTAGRMRFIMLHDTKNEDGIGNFFQEMYEIYIKYSMNPFYEPNTPIKSQAFE RKSQFYGRKYL--QIRMAHTDVQVPDFSEYRRDAVKASRKGFTYLMVAGGSMAAAYGGKS LAQEFITTMSASADVLAMAKIEINLGDIPEGKSATFKWRNKPLFVRHRTADEIAKEESVD VASLRDQQHDSERVQKPEWLILLGVCTHLGCVPVNGLGDYGGYYCPCHGSHYDASGRIRK GPAPLNLEVPEYSFQTETLLVVGMARQGSRGADPKKMSGELFTLTYGSLVAQLLKDYESD EEVNKQLERMGYNIGVRLIEDFLARSNVGRCHDLRETADVIAKVGFKMFLGITPVVTNWS AAGDEFSLLLENNPLTDFVELPEGHSNLNYSNIMCGALRGALEMVQMDVGVWFVQDHLKG DNITEIRMRFIKRLEDAVPAGED------------------------------------- ------------------------------------------------------------ ------------------------RIGRFSEPHSRFYAAQIVLVLEYLHHLDIMYRDLKP ENLLVDVSGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVY EMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLKNLLQVDLTKRYGNLKNAVN DIKNHKWFSTTDWIAIYQKKVEAPFIPKCKGPGDFSNFDDYEEEPLKISSTEKCAKEFAD FMIADTLLILFISIATALLGEGLTWLLVYRTEKYIKLKAEVEKQSKKLEKQKEATGESAD RSHKKKIERQEERLKNNNRDLSLVKMKSMFAIGFTFTALLSMFNSIFDGRVVAKLPFLPI GLLQNLSHRNLVGDDFYDCSFIFVYILCTMSIRQNIQKLLGFAPSRAANKQGGGLFGA-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------LDCVQVLTGHTGSVLCLQYDENIIISGSSDSTVRVWSVKTGEMLNTL IHHCEAVLHLRFSDGIMVTCSKDRSIAVWDMQSPTDINLRRVLVGHRAAVNVVDFDQKYI VSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACL RVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLAAALDPRAPGGTLCLRTLVEHSGRVF RLQFDEFQIVSSSHDDTILIWDFLNMAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNS TFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKS FENIRNWIRNIEEHASQDVEKMILGNKCDMNDRRQVSKERGEKLAIEHGIKFMETSAKAS INVEEGFFTLARDIKAKMDRKLADGETSADRNVEIWKIKKLIKSLEAARGNGTSMISLII PPKDQISRVAKMLADEFGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVIYCGT IVTDEGKEKKVNIDFEPFRPINTSLYLCDNKFHTEALTALLADDNKFGFIVMDGNGALFG TLSGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAEVAVQLFIANDRP NVAGLVLAGSADFKTELSQSDMFDPRLQAKIIKIVDVSYGGENGFNQAIELASEALANVK FIQEKKLIGKYFDEISQDTGKYCFGVDDSLRALEMGAVEILIVWENLDIMRYVLKNHQTD EEKILFLKPEQEKDKTYFVDKNTGVELELVDSMALLEWFANNYKSFGATLEIITDKSQEG AQFVRGFGGIGGVLRYQVDFQSLEACDDFEEEFDLDDY----------KRNKDDEHYIHL IMEANAQSHKLYIMDARPSVNAVANKAKGGGYESEEAYQNAELVFLDIHNIHVMRESLRK LKDICFPSIDDSHWLSNIESTHWLEHIKQILSGAVRIADKVESNKTSVLVHCSDGWDRTA QLTSLAMLMLDPYYRTIRGFEVLIEKEWLSFGHKFAQRVGHGEDKHSDADRSPVFLQFVD CVWQMTRQFPNAFEFNEHLLITVLDHLYSCLFGTFLYNSEQMRIKERVRQETVSLWSFVN CQVEEFTNPLYTHVLFPVASMRRIELWTAYYIRWNPRMRPQEPLHLRNREL--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------PHEVLTMLTNENGFEISSAEATVKVLITTIPPNLKK LDPDLHLDAKLMQGHLAAIRHARWFEENAFHSSVKVLIRLLRDLRSRFEGMEPLTPWMID LLAHYSIMNNPNRQPLPLNIACRRCLQLLAAGFFLPGSAGISDPCESGNIRVHTSMTLEQ QDQVCYTAQTLLRVLSHGGYKQILGLEGDASIATEMSVWEGVVVTPSDKAYEKPEKVVRL IEQYLKENNLLRTLTSLQEESGISLNTVDSVDSFSSDINNGHWDTVLQAIQTLKLPDSKL IDLYEQIVLELTELRELGAARSLLRQTDPMIMMKQQQPDRYIHLEKMLERSYFDPREAYT EGQTKERRRAAIAQALAGEVNVVPPSRLLALLGQALKWQQHQGLLPPGQTIDVFRGKAAV REQEDEKYPTQLGKSIKFGQKSHVECAKFSNDGQYLVTGSVDGFIEVWNFTTGKIRKDLK YQAQDNFMMMDDAVLCMSFSRDSEMLATGGQDGKIKVWKIVTGQCLRRFERAHTKGVTCV TFAKDNSQLLSASFDQSIRIHGLKSGKTLKEFRGHTSFVNDAVYTQDGHHIISASSDGTI KVWNIKSTECQNTFKSLGGTAGSDITVHSIHPLPRNVEQFVVCNRSNTVVIMNMQGQIVR SFSSGKREGGDFVCATLSPRGEWVYCVGEDMVLYCFSITTGKLERTLTVHEKDVIGLNHH PHQNLIATFSEDGLLKMWKP---------------TPRLQTFWKYAKVELKPPGEMPQVS QGFNNLVAARTGKWAQVTVKEATLVAVEIAMWFFVGECLGKGTIVGYQIPGAVHFD--AI PKFYFKLPSEEEFLRLKLREESRAVFLQRRSRELLDNDELQSLWFLLDKHHTPPLVGDEQ MINYEDFTKVAAEAGPKCKPFFKPSVFSKLLQNDPYGRISIMQFFNYVMRKVWLHQTRIG LSLYDVAGQGYLKESDLENYILELIPTLPQLDGLEKSFYSFYVCTAVRKFFFFLDPLRTG KIKIQDILACGFLDDLLELRDEELSKDMQESNWFSAPSALRVYGQYLNLDKDHNGMLSKD ELARYGTGTLTEVFLDRVFQECLTYDGEMDYKTYLDFVLALENRKEPQALQYLFRLLDVQ NKGFLNVFDLNFFFRAIQEQMKVHGQEPVSFHDVKDEIFDMVRPADPYKLTLQDLINCAQ GDTVISILIDLNGFWKYENRE-EIVRGQPFEVGPRYSNLAYIGEGAYGMVVSANDNMTKT RVAIKKISPFEHQTYCQRTLREIKILTRFKHENIVDIRDIIRAPTIDQMRDVYIVQCLME TDMYKLLKTQKLSNDHVCYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFG LARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDVWSVGCILAEMLSNRPLFP GKHYLDQLNHILGVLGSPSADDLNCIINEKARGYLQSLPFKAKIAWSKLADQKALDLLDR MLTFNPHKRITVEEALAHSYLEQYYDPADEPIAEEPFTFETELDDLPREKLKELIFNETM LLNR-------------------------------------------------------- ----------------------------------FAIVVRNGDKMNVHAEELVVGDIIEV KFGDRVPADVRVVSAHGFKVDNSSLTGESEPQTRTAEFTNENPLETKNLAFFSTNAVEGT CRGLVISTGDRTVMGRIANLASGLEMGQTPIAREIEHFIHIITGVAVFLGVSFFIIAFIL GYYWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTI CSDKTGTLTQNRMTVAHMWFDNRIVEADTTEDQSDACYNSNSPTWKALASIAMLCNRAEF KMGQENVPVLKRECNGDASESALLKCVELSIGKVTDFRARHKKAVEIPFNSTAKYQVSVH PDEPQYLLVMKGAPERILDRCSTILINGEEKPLSEEWREAFNQAYLELGGLGERVLGFCD YHLDAAQYPHGYPFDSEEENFPLTGLRFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVT GDHPITAKAIAKGVGIISEGNETVEDIAARRNIPVSEVNPRDAKACVVHGSDLRDMTPAQ IDDILANHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIA GSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLLFILAD VPLPLGTITILCIDLGTDLVPAISLAYEQAESDIMKRQPRDPLHDKLVNHRLIGMAYGQI GMIQASAGFFVYFVILAENGFWPSRLLGIRMRWDSKAVNDLEDSYGQEWTYAQRKVLEYT CHTAFFVSIVIVQWADLMICKTRRNSIIHQGMMNHHMTFGLFFETTLAAFLAYCPGLDKG LRMYPLRWTWWVPPMPFSLIIFIYDEFRKYILRRNPGGWVEQETYY-------------- ------------------------------------------------------------ ----------------------------------------DKFPTPYANDEAAKAANNGA LPPDLSFIVNARHGGEDYIFALLTGYCDPPEGIEIREGMAYNPYFAGGAIGMAQQLYNEG IEYDDGTPATVSQMAKDVSVFLRYAAEPEHDERKRMGLKAMLIFLIAISYYYKRHKWTVL KSRKLAWVRPDQPSRCTYQLGKLSDSPHAHKSCNATILPSILHHIGNTPLVRLNNITRKD KIPCDILAKCEFFNSGGSVKDRIGLRMIEDAEKSGQLKPGDVIIEPTSGNTGIGLALAAA VKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTSASFDSPESHIGVASRLQQEIPNAHI LDQYRNPSNPLAHYDGTAEEIMTFRLLYEEGFFVGASSGLNVVAAVQVARNMGPGHTVV- ------------------------------------------------------------ -----------------------------TALCDTGQRY---------------MSDLGS EEEQGPYLGEYEGERNEREERHGKGKATLPNGDTYEGYYENGKRNGLGTYRFKNGARYIG EWSKNKKHGQGTFIYPDGSKYEGSWVDDQRCGVGKYYYINADTYEGEWQNHVRHGRGTYT YSETGTKYSGMWREGKREGHGELIHTNHKFVGPFKEDRPEGKGKYVFDIGCQQHGEYI-- -------------------------------------KCVGAIICKHDLHKKMVRRGYIA MLAVDQNYRRRGIGSHLVMKAIRAMVAEECDEVVLETEITNKAALRLYENLGFLRDKRLF RYYLNGVDALRLKLWLR---ALMFHLSPNQKKCLKEEIHKDVLVTGDYELSEAPGQKTSL LVTDSKSHVLYNKEDAKKGKFAFTTEEYDMFEVCFESKMLAGGHGADREIFVDMKHGVEA KNYADIAKAEKLKPLEVELKKLEDLSESIVNDFAYMRAREEEMRDTNESTHSRVLYFSVF SMCCLLGLATWQVLYLRRFFKAKKLIE--------------------------------- ---------------------------------------VVGANAGVVGMAKEHLGLALA LNVPVFVVVTKIDMCPPNVLAETLKMLQRILRSPGCRKIPVLVQSTDDVVVSATNFTSER MCPIFQVSNVNGENLDLLKMFLNLLSTRLVDEPPEFQIDDTFSVPGVGTVVSGTTLKGVI RLNDTMLLGPDPLGQFMSLAIKSIHRKRMPVREVRGGQTASFALKKSQIRKGMVLVAPRL EPKACWEFEGEILVLHHPTTISAKYQAMVHVGSVRQTASILTMSEEHLRTGDKAQVRFRF IKNPEYLRRDMRMVFREGRTKAVGTVTKLFPHVSANTRQQRAAKKAQE------------ ---------------VAFSPDFEMMVTGSDDERVRIFNAVTGKFVCKLKGHTGAVRAVAV -APNSKAFASASYDKTIRIWRTPDVECLQVLEGHSKSIECLAFSFDSKLCSGSWDKTAII WDVEKIFEGHTNLVQSVAFSNNSRWLATGSWDHTVRLWTEPVRVLRGHRGNVHAVAFSKE -GMLATGAWDKTVRLWAPRNG--------------------------------------- CVLRGHGGWVMALSFSPDSLLLASASQDDTVRVWDVVTGKPLKEMEGKTETVAQCGFGPG GAIVASGAANITLAL--------------------------------------------- ------------------------------------------------------------ ----------------------------ITDTVTGKSTSVSGTLPTGQLSNVPWRRTGVK YTNNEAYFDVIEEIDAIIDKSGSTVFAEIQGYIDCLIKLSGMPDLTLSFVNPRLLDDVSF HPCVRFKRWESERILSFVPPDGNFRLISYHIGAQNMVAIPVYLRHSISFKEGSSGKLDIT VGPKQTMGKSVENLVIEIPF-----------SQGKYTFDPVTKIMTWDAGKIDTAKLPNI KGTINLQTGVPPPDSNPTINVSFSINQLAVSGIKVNRLDMYGEKYKPFKGVKYVTKAGKF QVRTMATQVGPGSRYATSDWFTSNYTISTNAERQRGASHDIRQEGRFMRNETDNKTKWDQ SDNNTRLSDRVDMIRKWKDILEKTLADTDKEIKDLSDTKDLLECSLEAKNLPTEVNIENL VTREQRRSIDVVEDEVEHQLHQEQKVIEGIKKQLQQKIDECFEQLCLLQEARQQLLADLQ DKNVALGIDVDQYNLTEESPGISYKPDPLRVPKG-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PPAPGGEEPLPEALFWLLMTGNVPTEAQVKAISKEWANRADLPSHVVTMLNNFPSN LHPMAQFSAAITACNSESKFAKAYSDGVKKALYWESAYEDSMDLIAKLPTIAAIIYRNLY RDGTSVGAIDPEKDWSANFTAMLGYEDAQFTELMRLYLTIHSDHEGGNVSAHTTHLVGSA LSDPYLSFSAGMNGLAGPLHGLANQEVLVWLTRLKYTEDQLKEYIWTTLKSGVVVPGYGH AVLRKTDPRYQCQREFALKHLPKDPMFKLVSDVYKVAPNILLEQGKAKNPWPNVDAHSGV LLQYYGMTEMNYYTVLFGVSRALGCLSSLIWDRALGLALERPKSMSTEGLMKLVKMPWKA PVGEKCIRCEKSVYAAERMEAGGKIWHKLCFRCNTCDMLLKLNNYSQDQGKLYCKAHFQE YVTSQN---DKLFVHRDTAENNPETPFVFTPDNLKRAQVIIGNYPVGHQAAAVMPLLDIA QRQNNWLPISAMNYVAEMLKMPKMRVYEVATFYTMYNREPVGKYHIQICTTSPCMLGGIG SERILETIKTNLGIKCGQTTSDKLFTLEEVECLGACVNAPMVQINDNYYEDLTEKDMEEI LEDLKAGRTPKAGPRSG---RFSAEPAGGLTTLTEPPKGPGFGVRPDLMQKYEKLEKIGE GTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHS EKKLTLVFEYCDQDLKKYFDSCNGEIDPDVVKSFMYQLLRGLAFCHSHNVLHRDLKPQNL LINKNGELKLADFGLARAFGIPVRCYSAEVV----------------------------- ------------------------------------------------------------ -----------------------------------------------------VRYPQEE DCDGWPLEYCEYHPNYAKAKEWMEKNLADDMKALYLRRQTRGGKGVIKTKKKQTPQRIGV SRASRGKKKYVTVVTGLATYEIDLKVASKAFGSKFACGSSVTGDDEIVIQGDVKDDLFDF IPEKWPTIDEDNIDDLGDQKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSLETVPKELRNMRACLLCSLVKTIDQFEFD GCDNCDEYLHMKNNRDAVYECTSSSFDGLVAVMGPEDSWVAKWQRVNRFVKGCYAISVTG RLPPGVIRELKSKGITYRSRDTS------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------QQNGLVPIVEPEVLPDGTHDLETARKVTEQVLAFTYKALADH HVFLEGTLLKPNMVTAGQACEKKYTPQEVAKATVNALQRTVPAAVAGVTFLSGGQSEESA XVHLDAVNKKPWALSFSFGRALQASVLAAWQGKAENVKAAQDQLVARAKANGQAALGQYG GGVAGATGDSLFVANHAY------------------------------------------ ------------------------------------------EEDTKGVPQFWLTTFKNV DMLSEMVQEHDEPILKHLTDVKVRFLMGFCLDFHFESNDFFTNTVLTKEYIMRSEPDETE PFGFEGPEIIKCKGCTVDWKKGKNVTVKVIKKVQKHKGRGTKRTVTKTVQNDSFFNFFTP PEVPEGEPDEDTEALLTADFEIGHFIRERIVPRAILYFTGEALEEEEEGEEEDGDIILLK EGTDTSQGKPQLISNINACNAIVDAVRTTLGPRGMDKLVVDQGGKATISNDGATIMKLLD IVHPAAKTLVDIAKSQDAEVGDGTTSVVLLAGEFLRQCKPFIEEGVHPQIIVRAFRKATH LAVERINEISVKVKRKPEELRALLIKCAATALSSKLVARQKEFFSEIVVDAVMQLDELLA LNMIGIKKVKGGALEESKLIGGVAFKKTFSYAGFEMQPKNYATPKIALLNIELELKSERD NAEVRVDSVEEYQAIVDAEWEILYSKLQKIHESGAKVVLSKLPIGDVATQYFADRDMFCA GRVPDEDLRRTMKACGGSIQTSASSLTLGTCDKFEEIQIGGERYNIFMGCPKASTCTLII RGGSEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKEQLL IGAMAKALEIIPRQLCDNAGFDATNILNKLRQKHAGMWYGVDILNEDIANNYEAFVWEPC VVKINALTAASEAACMILSVDETIKNPKLDQGGGGGGRGRGRPM---------------- ------------------------------------------------TRVRAGKGFTLD ELKAAGVGKKQAATIGIAVDYRRRNRSVESLQQNVQRLKEYRSKMILFPKKTSKPKKGDA TAEEVKMATQLKGDVMPVRNYIRREKARAITAEERKGSVFVALRQARSHKRLFG------ ---MPNIKIFSGTSHPDLAQKIADRLGIELGKVVTKKFSNQETCVEIGESVRGEDVYIVQ SGCGEVNDMLMELCIMINACKIASACRVTAVIPCFPYARQDKKDKSPISAKLVANMLSVA GADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENIPEWRNSIIVSPDAGGAKRVT SIADKLNVDFALIHKERKKANEVSSMVLVGDVRDKVAIMVDDMADTCGTVSHAAEKLHEA GASKMYSITTHGIFSGPAISRINNSMFECVVVTNTIPQDEKMKLSPKIRCIDISMMLSEA IRRTHNGESVSYLFSHVPL----FYEHKFPEVEDVVMVNVRSIAEMGAYVHLLEYNNIEG MILLSELSRRRIRSINKLIRVGRSECVVVIRVDKDKGYIDLSKRRVSSEEIAKCEEKFAK AKCVNSILRHVAELLKYETDEQLEELYQKTAWAYDRKYKKTGAAYEAFKHAVATPEILDE LELDEETKKVLINNIKRRLTPQAVKIRADLEVACYKYEGVDAVKKALKAGLELSTEDMPV KINLIAPPLYVMTTQTLERADGMARGQQKIQSQQKAAEKAAKLKHDQKKSAAVALTYVCT ECKAQMPDPKTYKQHFENKHPKKPLPDQLKDL-----------QGVMTIPKGHCAACAKP IVGQVITALGRIWHPEHFTCSHCKEELGTRNFFERDGVPYCERDYHNLFSPRCGHCNGPI LDKCVTALDKTWHPEHFFCAKCGRLFGDDGFHEKDG------------------------ -----------------------------------------------------CMKPITG RCITAMYKKFHPEHFVCAFCLKQLNKGTFKEQNEKPYCHPCFVKLFMRPLTDEETKTFFE KLSKYIGENIKLLIDRPDGTYCFRLHKDRVYYVSEELMKRAANIARPNLVSFGTCFGKFT KTGKFRLQITALEFLAPYAKFKIWLKPSAEQQFVYGHHVMKSGLGRITENCPQYQGIIVY SMADLPLGFGVSAKGTTECRHADPMAIVAFHQADIGEYIRSEDTLASQRKFFVGGNWKMN GNKASMDGIIKFLNEGNANTDVLVAPPTCYLPYVKEKLFNVCAQNCYKVEKGAFTGEISP AMIKDIGCGWVLLGHSERRHVFGESDQLIGEKTAHALAAGLSILPCIGEKLDEREAGQTE AVCFRQLKADEWSRVVIAYEPVWAIGTGKVATPEQAQEVHAALRKWLAENVSAEVA---- -------SGGNCKNLAGQGDIDGFLVGGAALKPEFNDIINAR------------------ ------------------------------------------------------------ ----------------------------------------SWKDGLAFCALIHRHRPELI DYNKLSRDNPIENLNTAFDIAEKYLDIPRMLDAEDMVNSVKPDERSVMAYVSSYYHAFSG AQQAETAANRICKVLKVNQENERLMEEYERMASDLLEWIRRTTPWLENRTTDNTLAGTRD KLEEFRDYRRKHKPPKLEEKAKLETTFNTLQTRLRLSNRPAYLPTEGKMVGDIANAWKGL ERAEKGFEEWLLSELQRLERLDHLAQKFKHKCDIHEEWAYGKEDMLQAQDFKMCKLNELK ALKRRHEAFESGLAAHQDRVEQIAAIAQELNSLDYHDSPAVNARCQRICDQWDLLGTLTG QRRTALEEAERILERIDQLHLEFAKRAAPFNNWMDGAKEDLVDMFIVHTTEEIQGLIDAH EQFKGTLGEADKEFNGIIGLIQECQRIAQQFGIHGAADNPYTTLTAQDIAHKWSEVKLLV PKRDSTLQAEMIRQQNNERLRRQFAQKANLVGQWIERHLDSVASVGVQKGSLEDHLNKLK GIEKEVMAFKPNIDELERYNQEVQEAMIFENRHTQYTMETLRVGWEQLLTSVARNINEVE NQILTRDSKGISNEQMDEFRKSFFHFDKNRSRRLDPKEFKACLVSLGYNIRDDNKGDMDM RRIMAIVDQNNTGHVTFDAFLDFMTRETTDTDTAEQVMQSFKILAGEKPYITAEILRREL PPDQAEYCIHRMTPYVGRDAIPGALDYTSFSTALYGESDLNKLAIDSIELKDKRVLIRVD FNVPLKGTEITNTQRIDAAIPTIKYALEKGAKSVVLMSHLGRPDGKPNPKFSLKPVADAL KKILEKDIQFLSDCVGAEVEAACADPAPGSVILLENLRFHIEEEGKGVDADGQKVKADAA KVEEFRASLSKLGDIYVNDAFGTAHRAHSSMVGCQLPQKASGFLMKKELTYFAKALDKPE RPFLAILGGAKVKDKIQLIESMLDKVNEMIICGGMAYTFNKVLDDMKIGTSLFDEEGSKI VQKLMDKAKANNVQMHLPTDFITADKFDENPAVGTATKESGIPDGWMGLDIGPESITQFT EVIGRAKTIVWNGPAGVFEFEKFAKGTRGLMDAVCHVTTKGATTIIGGGDTATCAAQWGT EDKVSHVSTGGGASLELLEGKVLPGVAALSEA---------------------------- ----PNTCRNFAELARRGYFNGIRFHRIIKDFMIQGGDPTGTGRGGASIYGKQFDDEIHD ELKHTGAGILSMANSGPNSNGSQFFITLGPTQWLDGKHAIFGRVASGMMVVKRIGLVETD NNDKPVDDVKILRRRSRS--KKRSRSPR-RKKPYKYWDVPPPGFEHITPLQYKAMQAPIP FAGSAISRQARRLYVGNIPFGVTEEMMMDFFNTQMKMAGLAQAEGNPVIACQVNLDKNFA FLEFRSVDETTQAMAFDGINFQGQSLKIRRPRDYQPLPGMAETPSVGVVSTVVQDSPHKI FIGGLPNYLNEDQVKELLTSFGPLKAFNLVKDSGTGLSKGYAFCEYVDQACAGLNGMQLG DKKLIVQRASVGAKNAQQTPVQIQIPGLNMTQVPTEVLCLMNMVMPEELEDEEEYEDILE DVREECAKYGVLKSLEIPRPIKGVEVPGCGKIFLEFNSMIDSQKAQQALSGRKFSNRVVV TSYYDPDKYHRREFFLPLFDRVLVQRAAKETTTKGGIMIPEQAQGKMLEATVIAVGPGAR TNTGDIVPPSVKAGDKVLLPEYGGNKLEFDNDEYFLFRDSDILGKFQRLKSQIPDIKTSL DIVKHMQLKKEELQTHFQLSDTLFVKARVPPTEKVCLWLGANVMLEYNLEDAEQLLSKNA ATRTLEQVEEDLGFLRDQTTTIEVNMARVYNWDVKRRQ----MADEALAKAGLHFDELNK IRVLEPEVSQQTTELKEECKDFLDKMVEFQKIVGGFIELVDNVSKEVEKEKMKAIGSRNL LKSVTKQREAQQQQLQALIAEKRMQSERLRIQHESLLKEEADQNDFIEQFILQK------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------FHDAEDAKKALEQLNGF ELAGRPMKVGHVTERTAEASILDSDEMDRAGIDLGATGRLQLMAKLAEGTGFQIPQVAAN ALNMNPAQATPPIATQCFMLSNMFDPNASGPGWETEIRDDVIEECNKHGGVLHIYVDKAS PQGNVYVKCPSISAAVASVQALHGRWFAGKVITAAYVPLPNYHALFPEAVRSQQLLM--- -ERDDEVSPIPPPAPKKRSRRGAVSAEVYTEEDAASYVKKVVPKDYKTMAALSKAISRNV LFSHLDDNERSDIFDAMFPVHRHAGETIISQGDEGDNFYVIDIGEVDVYVNNELVIVISD GGSFGELALIYGTPRAATVKAKTDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLGKVSIL ENLDKWERLTVSDSLEPVQFEDAQEIVRQGDPGDDFFIILEGMASVLQKRSENEEPVEVG KLGPSDYFGEIALLLDRPRAATVVARGPLKCVKLDRGRFERLLGPCSDILKRNIAQYNSF VSLSV------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------AKDGGQAVVTKLKCAAGL AELATKKYKSAAKYFLQASFDHTDFPELQSANDVAKYGALCALASFDRQELQKHVISSSS FKLFLELEPQLRDIIHKFYESKYASCLKLLDEIKDTLLLDIYLAPHVTTLYIQIRNRALC QYFSPYLSADMNKMATSFNTTVAALEDELMQLILDGQINARIDSHNKILYAKDIDQRSST FEKSVLMGREYQRRTKALILRSAMLRNQIQVKSPPREGGQGGEMSIAPGSAAS------- ------------------------------------------------------------ ------------------------------------------------KFLMRNLALAGG VILLLAESKAEGKSLFAGLPSLGENTHKTYMQLSGRILLVLMFLTLLRFEFNFLQLLQNL IGTVLILLIAVGYKTKLASLILVIWLTCLNFYFNAWWTIPDYKPMRDFLKYDFFQTLSVI GGLLLVVALGPGGYSMDEHKKKWRQTVTMIPGDGVGPELMGSVKDVLSAAGAPVDFEELF VSRNRVCLKGIVSTPLATLNMKIRNELDLFANVVKVQSLPGFATRHNNLDFVIIREQTEG EYSALEHESVPGVVESLKIITRQNSQRIAKFAFDYATKHGRSKVTAVHKANIMKLADGLF LDTCREVSSLYPKIAFEEMIIDNCCMQLVSNPHQFDVMVMPNLYGNIVDNLAAGLVGGAG VVPGESFSADVAVFEPGARHAFASSAGKDEANPTALLLCAANMLNHLHLEYHGAIIRNAL EKTIKTGKVRTRDMGGYGTRTAFTIEVIRNV----------------------------- ------------------------------------------------------------ ----------------------------CFAKFHPNLIIGGTYSGQIVLWDNRSNKRTPV QRTPLSAAAHTHPVYCVNVVGTQNAHNLISVSTDGKMCSWSLDMLSQPQDSMELQFKQSK VAVTSFSFLSGDVNNFVVGSEEGAVYTACRHGSKAGIADMFEGHQGPVTGIDCNSVPGSV DFSHYFLTSSFDWTVKLWNIKENRPLYSFEDNSEYVYDAKWSPINPALFSTVDGSGRLDL WNLNNDTEVPTASVVQTALNRCKWHQSGKELAAGDDVGKIHIYDIAEPVATPRHDEWARF VHTLSDLKNEKAEDEE--VEAQLMHAAQMAEAQLDAQIEKLDNLDEDDMESLRRKRLATM KKQQAQRQEWLVQGHGKYEEIPEEKEFFEVCKKNKRVACHFYRDSTERCKIIDKHMAELA PKHMETKFCKINAEKCPFLTQRLRIKVLPTICMSKDSKTCDWIIGFDDMGGVDDFPAEML EWRMGQNDIVHYSGDLLTPPWQPNPKKTIKDNDSDSKTIVLVGHGGYDKLKIQQNDSPAK DQVLVHVKATGVNFSELMCRAGMYDRCPKLPAVLGWEGAGIITEVGEGVDQFTVGDRVMC MQGMWTEYAANVFLIPDEMTFEEAAAIPVTYVTAHICLFNFGNLRPNQSVLLHMAAGGVG TAATQLCKTVENVTLFGTASAKHDQIKENGVTHPIDYRTTDYVAEVKKVNPDGVDIVMDP LAGDDASKGYNLLKPLGKIIHYGGTNFVTGTTKNYMQMIKTWWSTKSINPLHLMSQNKAV CGVNL----VLKEIIQLYKDGKIKPVIDSVWAYEDVDLAMAKMHDRKNVGKVIL----MS RKHTPSDFLKQIIGRPVVVKLNSGVDYRGVLACLDGYMNIALEQTEEYVNGQLKNKYGDA FIRGNNVLYISTQKRRV--SSQAQLLLSRQLKELNKNPPQWFSAGLIDDDDLYKWEVVII GPSDTFYEGGFFKANLIFPKEYPQKPPKMTFMSEIWHPNIDQAGDVCISILHDPGEDKFG YERPEERWLPVHTVETILVSVISMLTDPNDESPANIDAAKEWRDNRSEFKKKVSLCVRKS LE----------RDTLVEYGRYVGECLPKYVQSVQVSHGNELELMIHPDGVVPVLTFLKE HTNGQFLSLADIAGVDVPTRQCRFEIVYNLLSLRFNSRIRVRTYTDELTPIQSACAVFKA ADWYEREIWDMYGVFFAGHPDLRRILTDYGFEGHPFRKDFPIQGYVEVRYDDEVKRVVAE PVEMAQEYRKFDNSSPWEIFPAYRE-LNPFCQVDYRAKVWTCNFCFQRNSFPPQYASISE QHQPAELIPQFSTIEYTLTRAQCHPPVFLIVLDTCMDEEDLQAVKESLQLSLSLLPPNAL IGLITYGKMVQVHELGAEGCSKSFVFRGTKELSAKQIQEMLGIGRGTAQLPSNRFLQPLH KCDMALTDLLSELQRDPWPVSQGKRPLRSTGAAMSIAVGLLECTYPNTGARIMTFVGGAC TQGPGMVVNDELKNPIRSHHDIEKDNCKYMKKAIKHYESLACRSADNGHIIDLYSCALDQ TGLHEMKFLSNYTGGHMVMGDSFNTSLFKQTFQRVFSKDVMNEFKMSFGATLEIKTSREL KVQGCIGSCTSLQVSSSVSDTEMGAGGTCSWKMCGLYPNTTYAYYFDVVNQHNAPIPQGG RGYIQFITQYQHSSGQKRVRVTTVARNWVDASINTQHIAAGFDQEAAAVLMARVAIHRAE TDDGPDVLRWLDRMLIRLCQKFGDYHKDDANSFRFSEQFTLYPQFMFHLRRSQFLQVFNN SPDETSYYRHSLLVEDLTQSLIMIQPILYAYSFSGPPEPVLLDTSSIQADRILLMDTFFH ILIYHGETMAAWRKAGYQDLPEYENFKQLLQAPVDDTQEILQTRFPMPRYIDTEAGKSQA RFLLSKVNPSQTHNNMYADQGGHVLTDDVSLQVFMEHLKKLAVSTASMTTLSAEDQLKLI QDLEIEMMADMYSRMSNACQAKCVPPKYKDAELNKGEAVCIDRCVAKYLEVHDRIGKKLT AMHGQDEETMKKLQA-----VIHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYR KKVVLDGEEVQIDILDDYAAIRDNYFRSGEGFLCVFSITEQESFQATADFREQILRVKND ENIPFLLVGNKADLEARRHVTIEEAQTRAQQWKVPYVETSAKTRANVDKVFYDLMRQIRS NKSTKEKRKRKCTIL--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------EMENSGVAHMLKNIKTEDL ACMFKLFFRVPNGPKTMSDCISSYLREQGKALVKEEDSGKNAITFVQTLLDLKDRFDHFL HESFSDEKLFKQMISSDFEFFINLNTKSPEYLSLFIDDKLKKGVKGMSEQEIENVLDKSM VLFRFLQEKDVFERYYKQHLAKRLLLNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFKD MTVSNGTMDEFKSHVQTGTNLHGVDLFVRVLTTGFWPTQSATPKCNIPTSPRNAFEAFRR YYLAKHSGRQLTLQPQLGSADLNATFFGSKKDDGETTIGQRKHIIQVSTYQMVILMLFNQ RERLTYDEIKSETDIPEKDLMRAIQSLALGKMTQRILTKEPKTKEIEPDHLFMVNDQFTS KLYRVKIQTVAAKGESEPERKETRSKVDEDRKHEIEAAIVRIMKARKRMQHNVLVAEVTE QLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKIYTYVADRLPIFPSRMNLQLMKVKLK GAEKGHSLLKKKADALTMRFRQILRKIIETKTLMGTVMKEASFSLAEAKFTTGDFNHLVL QNVSKANVKVRSKTDNVAGVSLPIFESYTDGTDSYELTGLSRGGQQIDKLKKNYAKAVEL LMDLASLQTSFITLDEVIKITNRRVNAIEHVIIPRVQNTLSYISSELDEREREEFFRLKK IQKKKAEVRGANLLEEYDEDLLFPIRVLVTGAAGQIAYSLLYPIANGDVFGKDQPIILVM LDIQMMMDALGGVVMELQDCALPLLKEVIATSDPAVGFKDIDVAALVGAMPRREGMERSD LLKANGKIFEAQGKALDQYAKKDVKVLVVGNPANTNAFIIKKFAPSIPTQNFSCLTRLDQ NRAQAQIAARDAVRNVIIWGNHSSTQFPDVSHAFVVYEAVQDEAWLKNEFVKTVQTRGGA VIKARKLSSALSAAKAICDHLRDWWVGTKEGEFTSMGVCSDGYGIEKDLMYSFPVTINGQ WSIVQGLSISDFAREKMDATHKELCDERDSAM-------GVLMVGPNFRVGKKIGCGNFG ELRLGKNLYNNEHVAIKLEPMKSRAPQLHLEYRFYKQLGQSEGIPQVYYFGPCGKYNALV LELLGPSLEDLFDICDRKFSLKTVLMIAIQLISRMEYVHSKHLIYRDVKPENFLIGRQSN KRQHLIHIIDFGLAKEYIDTETRKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEAL GHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCESFPDELATYLRYVRRLD FFETPDYDYLRKIFTDLLAQKGFENDCEFDWTGRQV------------------------ GPISPA------------MTTIRPFTCDDMFKYNNVNLDPLTETYGLPFYMQYLAHWPEY FQIAESPSGQSMGYIMGKAEGHGENWHGHVTAVTVAPEFRRLGLAAKLMNILEETSEKKH CFFVDLFVRVSNKVAVDMYERLGYSVYRRVLEYYSGDVDEDAFDMRKALSRDTDKRSVVP LEHPVRPEDLEQQLDCALDLMRRLPPQQIEKNLTDLIDLVPSLCEDLLSSVDQPLKIARD KSLGKDYLLCDYNRDGDSYRSPWSNTYDPPLEDGAMPSERLRKLEIDANTAFDQYRELYF EGGVSSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHV------------------T AMLWLQTNKSGSGTMNLGGSLTRQVEQDSTVSEGSPHIVNIGRMVEDMENKIRNTLNEIY FGKTRDIVNGLRSSQSLIKENLRNDLAKALQARS-------------------------- ---RVDNAKRITTPYMTKYERARVLGTRALQIAMCAPVMVELEGETDPLMIAMKELKAKK IPIIIRRYLPDGSFEDWAIDELIISE-----------PAGDGAFTMGRGLVAGASVVGIG ALCFYGLGMSNEVGAIDRASLWPDIVKSRIRDTYFYFGSSLVFTAISRSPRMMSLMMKNS WMAIIGSMVAMIGTGMVARSIPYQEGSKQLAWMLHAGVVGAVIAPITLLGGPLLIRAACY TAGAVGGLSTLAMCAPSEKFLTMGAPLAMGLGVVLISSIGSAFLPPTTALGAGLYSISIY GGLVLFGAFLLYDTQKIIKRAETHPVYAATPYDPINNSISIYLDTINIFIRIATILAGGG NRRRMEIVYVYTKKRAEFGRQCNFSDRPAELHVDIVPDKTLTESFIERNPVDTSTQNVQE MSEHEVNTERFETDTRGINHIEGGWPKDVNSTEIEQVMRYRKKVEKEEGYMFTVQQLSGV MEHCIKQNNAIDIYEEYFDDLEVDLDEEVPSAKTINVFRDPNEQKRTSTHISWFPDGPRK LAIAYCNLEFQGNSPDTMDSYIWDVDNPNKPEMTLKPVSPLVCLEYNPKDSHILIGGQYN GQIAYWDTRKGSQPVEMSPIEHSHRDPAYKTIWLQSKTGTECFSASTDGQVLWWDTRKLG EPTEKLYLDPTKKQDFSKAQGAMSLEFEPTMPTKFMVGTENGTVMSCNRKAKTPGEKIVA IYPGHHGPVYALQRNPFFPKNFLTVGDWTARIWSEDIRESSIMWTKYHMAYLTDGCWSPV RPAVFYTTKMDGTLDIWDINFKQNDPTLSLQVCDEPLHTLRVQDNGRLIATGSQSGTTTL LELSDSLCTQQRNEKGLVTAMLERETRREKILESRHREMKLKERTKSSWDELVGQVGPIA NPLASRKLTKKLFKVVKKALRKGIREVQKFVRKGEKGMIIFAGNTSPIDVISHMPMVCEE KEIPYCYVPAKEDLGLASGSKRPTCMLMIKPHDDYQDLYDQCFEELQGLPLPVMPLENLE DEGLEKNPNLDLAQKKFLLTTDEYRNDSKLKKELLAAIEQDNMAPFYEEVCAEFSWPVNA ALLDQMKAENETKLKEIDAKVEDAEKNLGETEVRDFMLKKAEYYCRIGAKDEAISQFRKT AEKTVAVGYKLDMVFQLIRIGLFHMDHDLIKRNLEKAQSMIDQGGDWDRRNRLKVYKGCY MMAIRDFKEAANLFLDTVATFTSYELMDYKDFVKYTVYCSMIALDRPDLRKKVVSGSEIL EILHSLPNVKQFLFSLYNCHYGDFFKALALVEVEMRYSRLLSPHYRYYVREMRILAYSQL LESYRSLALDYMATTFGVRQEFIDQELSRFIAAGRLHCKIDKVGGIVETNRPDSKNWQYQ STIKHGDILLNRIQKLSRVINI-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------IVRAFDTREAVRE QVQSMGAEFLEVNIKESGEGAGGYGKTMSKEFIEAEMALFAKQAKEVDIIISTALIPGKV APILITKEMVDSMKPGSVVVDLAAEAGGNIETTKPGELYFYNDVCHIGYTDLPSRLPTQS STLYANNISKLLLSFGYNVDFNDEVARGSIVLHNGEMMWPAPVPKEINYFNVYMKDSMMY SAGMAGALGLGLGAPNAAFTAMLTTFGLAGIVGYHTVWGVVPALHSPLMSVTNAISGITA VGGLWLMGGGYFPSDTPQAMAAIAAFISAINIGGGFRVTQRMLDMFKRPDDPPEYYSLYA IPALGFMGGYGAALVYDYPHIHQMAYLAASLCCVGALTGLASQTTARLGSTLGMMGVSTG IVATLGLLQPTPEVLAQMCGTLGAGALLGMTAAKRIEVTDLPQMV--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------GYGLCVAKAQYPIAELVDVLKKKGKNVR FGIHPVAGRMPGQLNVLLAEAGVPYDIVHEMEEINDDMPQVDLTLVIGANDTVNSAAEED PNSIIAGMPVIRVWLSKQVVVMKRTLGVGYAAVDNPIFFKENSNMLLGDAKKTCDSLLQG VK-----AIPGVPAGLEYLVTVDQLLVHQQMELLEILTTWETSNKYAIKNSVGQQVYYCA EESNLCMRQCCGPARGFILHITDNFGNEVIRVTREFKCCAGCPCCAFCAFEITVEAPVGT VAGYVKQ----------DAILRVTGPLCQCQCICCPRDLPFDILTAEVGSITKQWGGILR EAVGDADMFGVKFPADLDVRVKATCLAAVFLVDFMYFETKQN--DPELQEFLMMEQQKAQ FQGTIHSMTDTCWDMCVDKPRDKMDYRTEACVTNCVDRFIDTTLQITQRFQQML----MN RTDGLVQRRNVAPEEDDHDSKETRLTLMEEVLLLGLKDREGYTSFWNDCISSGLRGCILI ELGIRGRIDLEKTGMRRRSLLNRKLICKNDTPTGDVLLDEALRHIKETQPPETVQNWIEY LSGETWNPLKLKYQLRNVRERLAKNLVEKGVCTTEKQNFLLFDMTTHPLVDSVIKSRLVK RVQDAVLSRWVNDPQRMDRRLLSLIYLAHASDVLENAFAPLSDEDYELAMKRVRELLDLE FEAESMKEGANEVMWSAIIAFAKGKKLTAATEENCEVCVKFLTKFIDNLPKIEKEFLKTC KAAKSAENRFCYYVGGTSDSATSTLNDLTKPISWGVPADKVCMKVYRKDEQICDLKYEKQ MDFVNANFKKLKVKDLKKILNDWEDNCRGCTEKDDYIRRIEELLPKYAPDAAPQAIMDGF KLNWMNLRDADSGKILWQGSEDLSTTGVEHEARVPKKILKCRAVSREINFSSKEQMERFR LEQRVMFKGRCLEEWFFEFGFVIPESTNTWQSVIEAAPENQMMPASVLNGNVIIETRFYD ADILVSTSRVRIFYVMPKVVSRSVVCTDTKDQEEYKGEKPLYVYYCLCGQMSLILDCPLD KLPMRRKDNARVIDSAKHAHKLTCEADETVHIKRSEGIERQYRQKCKKCGLLLYYRHRNQ VTFIVEGALKQSSDVTKDAY-EIPKRKKVMVTKHTKNMGKFSSVTVSTVDEEEEELEAKE IADSYAANAKVIEKQLLRKGINKKRMMEFAEEEAKKMRPKGTLIDLARHCARLATHQQSR SYAEMSFTFATASKVNVNQVDVPSFSGNFGILPDHVPLLAVLQPGVVTVYEKDNTTKKIF VSSGSVTINDDSTVQILAEEACGIEEIDAQSVREGLSKANADLSSEVAKAEAQIAIDCYE QLQKAMD----------------------------------------------------- ----------------------------------KGVEVKMDIPYELWDEPSAEVTKMHR ACFNLVEKYEDDIDEWYYNHQEDLADYICRQRYLKDRNG------VTSEADVKAALTAKE KYGKLDVSVNCAGIGIAVVTYNPKKDRVHDLADFAKILTVNTVGTFNVIRLSAQMMNENE PNVDGQRGVIINTASVAAFDGQRG------------------------------------ ----------------------------------------------------------SR DFHFRVDGRNTNAKEKISRDYPVVDHEYDAVVVGAGGAGLRAAFGLAREGFKTACITKLF PTRSHTVAAQGGINAALGNVEEDKWEWHFYDTVKGSDWLGDQDAIQYMCEEAPKAVTELE NFGMPFSRLKTGKIYQRAFGGQSLDYGRGGQAHRACCVADRTGHSMLHTLYGRSLHYDTD YFVEYFALDLIMEKGQCVGVIALNLEDGNIHRFHSKNTVLATGGYGRAYFSCTGAHTCTG DGGAMVTRAGLPMEDMEFVQFHPTGIYGAGCLITEGCRGEGGYLINSEGERFMERYAPTA KDLASRDVVSRSMTIEIREGRGVGPEKDHAYLQLSHLPQEQLAARLPGISETAQIFAGVD VTRDPIPVLPTVHYNMGGIPTNYKGQVITFNGTDKIVPGLYAAGESACVSVHGANR---- -------FGRGCALAIADENKPGETILEMNQNAGEESVANIDNLLNSNGSTPTADLRVKM QKAMQNHAAVFRDGPTLEEGCKKMADIYSDLDLKVTDKGMVWNSDLVETMELQNLMLNAM QTIYSAEARKESRGAHSREDFPDRIDEYDYAKPLQGQAMKPMEEHWRKHTMASVDHVTGK VTLDYRPVIDKTLDAARCETIPPKLRVYMTALTQDEILGSTKTVVQGLDTLKNEHNQILN SLLSSMKTIKKGDTNLVEEKTSILKKSLEMLELGLGEAQVMMALATHLQHVEAEKQKLRA QVRRLCQENAWLRDELANTQQRLQQSEQRVATLEEEKKHLEFMSEMKKYDMEGSLGFPED DDDVQSGAMAQAASGGCEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHD HPDVATMLNILALVYRDQGKYKEAANLLNDALGIREKTLGPDHPAVAATLNNLAVLYGKR GKYKEAEPLCKRALEIREKVLGKAHPDVAKQLNNLALLCQNQGKYEEVEQYYQRALEIYE TKLGPDDPNVAKTKNNLASAYLKQGKYKQ------------------------------- ------------------KMRLKANTLNAPFKQMENIQNFVEFCEAYGVHRNSTFQTVDL FDGTNMAQVISCLQTLGSEARRQRFQGPCIGPKPTNQNYRNFSYEQLREGHLQAGTNKCA SQSMGAVRHVADIRADDLTQEGAAIIGGQYGTHGASQKGMSMGAVRHVADIRADQFTAEG GAII-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --HSFGITPITCHAFNGDRSQLAIPNNHEVQIYKQKWDLIATLTEHVQRITGIDWAPRSN RIVTCGADRNAYVWPTLVILRINRAATCVKWSPQETKFAVGSGARLISVCYFELENDWWV SKHIKKPLRSTVTSLDWHPNNVLIASGSSDFKARVFSAYIKEVDEKPAAT---------- ------------------------------------------------------------ ---------YAYDGSEIKFHSKVDEKKFTAMSHFQNLDTRGQELASIHQNTISQVSIHTG DKSKAVKVSTSGLDAKLIIWDLKKEVEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGL GKSTLINSMFLADLYSAEYPGPSHRIKKTVNVEPTQVLLKEGGVQLRLTVVDTPGFGDAV DNSNCWHPVTEYIENKYDEYLNAESRVNRRTMPDNRVHCCLYFISPNGHGLKPLDVEFMK RLHDKVNIIPLIAKADTLTPDECREFKKTILNEIAQHKIKIYEFDDEEENKLQKKLKDRV PFAVVGSNTVVESQGRKVRGRMYPWGIVEVENLEHNDFIALRNMLIRTYLQDLKDVTNNV HYENFRY----------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ANVLTHELRLIAQRYLLQYGEPIPCEQLVSTLCDMKQAYTQFGGKRPFGVSLLYIGWDKH YGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQEYKEGETNLQEGLELSIKVLSKTLD TNKLTHEKVEIATLTRENGKTKIHILTPDETNALIKKHEEEVAKAEAEQKRELNEAWERL KQLSLRRQEKLFGAHEIQHFNRDADETIVWIAEKDVVLSTDDYGRDLASVQALQRKHDGV ERDLAALEEKVTQLGQESQRLTDTHPEQAPEINTKCDEIVHNWETLKRKAGERKVRLDDA YHLHRFLSDFRDLVSWIHDMRAIISADDLAKDVAGAEALLERHQEHKGEIDAREDSFRAT AEAGQRLMESDHYAVDEVKEKLVTLAEEKTSLLDLWEERRILYEQCMDLQLFYRDTEQAD AWMSKQEAFLANEDLGDSLDSVEALIKKHEDFEKSLAAQEEKIKALDEFATKLIENEHYA AEDVANRRDALLQRRNVLYNKSTMRRLKLEESYKYQMFERDCDETKIWINEKLKAASDEG YMDPTNLQGKVQKHQNFEAEVQANQARIQAVTENGQELIDSDHYASDQISERLDEIKGLW EQLVGQSERKGTKLKDANDQQAFNRNIEDVEVWLAEIEGQLMSEDYGKDLTSVQNLQKKH ALVEADIQSRQDRVDTVVMAADQFATKGHFDADTIVAKKATVVERYQQISEPMNQRRQKL SDALRLQQFFRDVEDEEDWIREKEPIVASTNRGRDLIGVQNLMKKHQALQAELAGHDSRI GRVKEQGTEMVNDGHFASDDIQRRTTMLSERWNNLKDKATQRRQDLDDSLQAQQYFADAN EAESWMREKEPIVGNTDYGKDEDSAEALLKKHQALMSDLEAYRSVIDSLHEQAAACKQQE APVVDDLGKECVVALYDYQEKSPREVSMKKGDVLTLLNSSNKDWWKVEVNDRQGFVPAAY VKKIDSSLTASQSNLADEFTISVRQQQIETQYENLLEVGHQREEKLEESCKAYQLVREAG ELAQWINDKETVALSDEIGDDLEQVEVIQRKFDDFQKDLKANEARLVELNTIAERLTAMG QTEAAEKIKIQIEDLNSRWAALQQVTSERAQTLGSAHEVQRYHRDADETKDWIEEKDTAL NTSDYGTDLATVQRLQRKHEGLERDLAALGEKVRELDEIANRLMQTHPDQAQSIYDHQKD INEAWNALTAKADQRKAKLLDSYDFQRFLSDQRDLTSWINSMMALVSSDELAKDVTGAEA LLERHQEHRMEIDARAGTFQGFETFGHQLLQNNHYASDEVRDKLKELADAREQLEDAWIA RRAKLDQCLELQLFVRDCEQAETWMAAREMSLSDDVDGSETVENLMKKHEDFDRAITSQE EKIAALQSFADQLVDSEHYDKSGITDRCTQVLGRWTDLKESLLDNRSKLGEAQNMQQFSR DVDEMEIWITEKLQMAMDESYKDPANI--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------Q------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------AIQCYQCDSNEDNSCPSNRYFDRNLNALIDCNSLEAHTPGLFCMKVSQQSPG WRAWTKITRRCGSRAEDGVAWGCRWFYEPNGVWRETCYCEDRDGCNGAATIDLKKEYQPS L---YVEGVVAYLKNREKKPIRPSARAVLVDWLIQVQDHINLETETLHLSLALLDHMLSV AMALSHVQLMGITCLFIASKMNERFPPKIDELLRLTEYAYKKEDLKAMERVVIKQLEFDV FIPTPVDFLERYIKVSAEDVDVKRMANFLLEHSLTDCLVMVKFPSLRAAAAVWLSRRLLL WTASLEFYSGFDEERVMEVVERMASQLLKKFQAAYEKYSS-------------------- -ARGRSRGRRQNNPSPGPENDLERVFIWDLDETIIIFHSLLTGSYAQRYGKDAPGSVSLG LRMEEMIFNLADNHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFTTDGFHAAATNNLCL ATGVRGGVDWMRKLAFRYRRIKEIYSSYRNNVGGLLGPQKREQWLQLRSEIEGITDSWLT LALKCLNIINSRSTCINVLVTTTQLVPALAKVLLYGLGGVYNIENIYSATKIGKESSFER IVSRFGRKCTYVVIGDGRDEEAAAKQMNWPFWRISNHSDLAALHHALDLGYLMTALALGG ERTTGQSVRTQNVMAAASIANIVKSSLGPVGLDKMLVDDVGDVTITNDGATILKLLEVEH PAAKVLVELAELQDQEVGDGTTSVVIIAAELLKNADDLVKCKIHPTSIISGYRLACKEAC KYIQEHMTMGIDDLGRDCLVNAAKTSMSSKIIGSESDFFSNMVVDAATSIKTPDGKGGFK YPIKAVNVLKAHGKSSKETMLINGYALNCTIASQLMKKSITNAKIACLDFSLQKTKMKMG VQLLIEDPEKIEAMRQREYDITKERIAKILATGANVILTTGGVDDLCLKYFIEGGAIAVR RCKKTDLKRIAKATGGQLVVSLANLEGEETFEASMLGTADEVSQERICDDELIIIRGTKA RSASSIILRGANDFMLDEMERSLHDALCVVKRVLESKTLVPGGGAVEAALSIYLENFATS LSSREQLAIAEFAKSLLVIPKQLAVNAAQDSTDLVAKLRAYHNTSQTKPEHRDLKWVGLD LHEGVVRDNKKAGVLEPAISKIKSLKFATEAAITILRIDDLIKLTPEQKQGSAYQQAMAR GELEEDNARLLASKNILNQLLVEGKDVTVEYTIFNVGGSAAHNVHLVDSSFPETDFERVR GFLSVKWPRIAPSTNVSHVVILKPLRSGYFNFTSAEISYLPSEDQPQMGYTSAPGEGGIM NFKDYDRKFSPHVLDWAAFAVMTLPSLGIPFLLWYSSKSKYDTPKQKKNGGGSQKERTEK YRVILDQIEGVKAFVESVVNENVSLVISRQILSELCTKLPTVPDEACKLICHFTLERVQP RVISFEEQVASIRQCLADIYERESNWREACNVLIGIPLETAQKQYPNDYKLKTYLKIARL YLEDEDPVQAEAFITRASLLQADSSDQQLQIYYKVCYARVLDYRRKFIEAAQRYNELSYK TIVAEEERMEALKNALICTILASAGQPRSRMLATLFKDERCQQLPSYGILEKMYLDRIIR SDSLQEFAAMLQPHQKAVTSDGSTLLDRAVIEHNLLSASKLYNNISFEELGSLLEIPAAM AEKIASQMITEGRMNGCIDQIEHIVHFESREALPTWDKQIQSLCFQVNNIIEKINTHEPA WMAK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------KDCDWTGLXFSPDGKLILISTNGSVVRLIDAFQGTPL QTFVGHTNMKGLALEASFSPDSQFVFSGSTDGKVHCWNTETGAKVVTLTCEHTGPVQCVQ FNPKYMMLASACSNMAFWLPQIDEEHIIVDKVGAKKNVGFIQLNRPKALNALCSPLMDEL SAVLTEFDNDQSVGCVVLTGSERAFAAGADIKEMGPKTFAGVYNEDFISKWTSLANMRLP VIAAVNGFALGGGCEVAMMCDIIYAGEKAQFGQPEITLGTIPGAGGTQRLTKAVGKSKTM EMVLSANRITAQEA---------------------------------------------- ---------------------------------------- >Helobdella_robusta MSDRKAVIKNADMSEDMQQDAVDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSGMMTLSRLMHTTAVRRDIDQAAKYIGAGAATV GVAGSGAGIGSVFGSLVIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLILFAFM SNLKDAGKAPEPTIHRIRITLTSKNVKSLEKVCGDLIRGAKEKQLKVKGPVRMPTKILRI TTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADMDQVM QYIEPAKTFAKDSIRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNII VMATQVSKKRKFVNDGVFKAELNEFFTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVL GEKGRRIRELTSVVQKRFNFPDGTVELYAEKVATRGLCAIAQAESLRYKLIGGLAVRRAC YGVLKFIMESGAKGCEVIVSGKLRGQRAKSMKFLDGLMIHSGDPMNDYVDQAVRHVLLRQ GVLGIKVKIMLPWDPTGKLGPKRPLPDHVTILDPKDQPIPEQPYSEQKGTKMSKRGRGGS SGGKFRITLALPVGAVINCADNTGAKNLYIISVHGIKGRLNRLPAAGSGDMVMATVKKGK PELRKKVMPAVVVRQRKAIRRKDGTFLTFEDNAGVIVNNKGEMKGSAITGPVAKECADLW PRIASNASCIRKAKVVKVTLGPQVAEGELVFGVAHIFASFNDTFVHVTDLSGKETIVRVT GGMKVKADRDESSPYAAMLAAQDVAERCKQIGITALHIKLRATGGNRTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRLMGKPRGLRTARKLKNHRREQRWNDKD YKKSHLGTRWKSNPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP WDGCLNFIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVASVSLLALYKGKKERPRSDSV ATVRTRKFLTNRLLCRKQMVVDVLHPGRSTVPKTEIRDKLASMYKTTSDVVFCFGFRTQF QGGKTTGFALIYDTLDVAKKFEPKYRLARHGSKKQRKERKNRQKKVRGTKKAKVGAMPRI ALVQSKTYSTPRRPYEKERLDQELKLIGEFGLRNKREVWRVKYALTKIRTAARELLTLDE KDPRRLFEGNALLRRLVRIGVLEESKMKLDYVLGLKLEDFLERRLQTQVFKLGLAKSIHH ARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLKSPYGGGRPGRVKRKNQRKPDSGA AAMGNIFTKLFQGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVGEAREELMRMLAEDELRD AVLLVFANKQDLPNAMNAAEITDKLGLHSLRQRNWYIQATCATSGDGLYEGLDWLSNQLK NQKMPLAKDLLHPSQEEEKRKCKLKRLVQSPNSYFMDVKCPGCYKIMTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRRKQHMVRMNVLADALKSICNAEKRGKRQVLIRPCSKV IIKFLTVMMKHGYIGEFEIIDDHRAGKIVVNLNGRLNKCGVISPRFDIKMKDLEHWTAYL MPSRQFGYLVMTTSGGIMDHEEARRKHLGGKILGFFFMGRMHAPGKGISQSSLPYRRSVP TWLKLSSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVKSVTSNKILRILKAKGLAPE IPEDLYFLIKKAVAIRKHLERNRKDKDAKFRLILVESRIHRLARYYKTKKVLPPTWKYES STASALVSVVEAQDVKLFGKWSAEDVNINDISLTDYIAVKEKYAKYLPHSAGRYQAKRFR KAQCPIVERLTDSLMMHGRNNGKKLMAMRIVKHAFEIIHLLTGENPLQILVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREASFRNIKTISECLADELINAGR GSSNSYAIKKKDELERVAKSNRMTEQMTLRGTLQGHEGWVTQIATTPTYPDMILSASRDK KLICWRLTRDGRYGYPQKALHGHGHFVSDVVLSSDGQFALSGSWDSTLRLWDLSTGQTTR RFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIEDCHTGWTSCVRFSPNT QNPLIVSCGWDRIVKVWNLTNCKLKTNHHGHSGYLNTVTVSPDGSLCASGGRDSQAMLWD LNEGKHLYTLDGVDTINALCFSPNRYWLCAATGPSIKIWDLEGKVVVDELKPELINTS-K SPDCLSLAWSADGQTLFAGYTDKLIRVWQVSVTARMREYKLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKHVEIDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTFNDLQDLREQILRVKDLEEVPMILVGNKCDLEDERVVGKLARSWNCAFLETSAKSK LNVNEIFHDLVRQISKKTPELMAEEKK-SDEHINLKVTGQDGSVVHFKIKKNTPLRKLMS AYCERTGVKMGSMRFRFDGQPINETDTPSQLDMEDGDAIDVFQQQTGGMSALPLNPKPFL NGLVGKPVLVKLKWGMEYKGYLVSVDGYMNLQLANTEEYMDGALSGNLGEVLIRCNNVLY IRGVEDIDEEGEMREMSDAEGDDAPAVVAAGGPMDLNTAIQEVLKNSLIHDGLAKGAHEC AKALDKRQAHLCVLANNCDEANYVRLIEALCAEHNINLIKVDDNKKLGEWAGLCKIDKEG KARKVVGCSCVVVKDYGKESPALDVLNEYFKSRKMAAIRKKLVIVGDGACGKTCLLIVFS KDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSI DSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRGDEATRRELMKMKQEPVRPEEGKA MSEKINAYAYLECSAKSKDGVREVFETATRAALATRKKKKGLMEDGLTSEETTFVVDDVS NVIKEAIESAIGGSMYQHSKVNPWTNNVVEQCLNQLSKLGKPFKYIVTCVIMQKSGAGLH TASSCYWDSITDGSCTIRWENKTMYCIVSVFGVAIMYSTNAKIVKLPGEKPDELESSISQ ALLELEMNSDMKTQLRELTFTGAKEVDVHNKKAIIISVPVPQLRSYQKVQSRLVRELEKK FSGKHVVFIAQRRILPKPTRKTRRKNKQKRPRSRTLTAVHNAMLEDLCFPSEIVGKRIRI KTDGSQIIKVHLDKSQQTNVEHKLDTFTAVYKKLTGKDVVFEFPEYVLGRGGFRGGFGGR GRGRGRGRGRAKEGDKEWVPVTKLGRLVKEMKIKTIEEIYLFSLPIKEFEIIDFFLGSSL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDFNGHVGLGVKCSKEVATAIRGAIILAKLSI VPVRRGYWGNKIGKPHTVPCKVTGSCGSVEVRLIPAPRGTGIVGAPVPKKLLHMAGIDDC YTSANGQTATLGNFAMATYEAIANTYAYLTPDLWKETVFVKSPYQEHTDFLMKMSGGLDA LALREADVAKFLACGTHLGTSNLDFQMEQYIFKRKAEGTYIINLRKTWEKLLLAARAIAA IENPADVCVISARPYGQRAVLKFASYTGATPIAGRFTPGAFTNQIQAAFREPRLLVVTDP RTDHQPVTEAAYVNIPVIALCNTDSPLRYIDIAIPCNNKSIQSIGLMWWLLAREVLRLRG TLSSDVPWDVMVDLFFYRDPEENEKEFSTEQWGADSV---APQTTDDWSATDTGDWSNAV PTTEWGGMKFNKSVSGSRRKNRRRHFNAPSHIRRKIMSSPLCKELRQKYNVRSIPIRKDD EVQVVRGHHKGAQVGKVVQVYRKKYIIHIERIQREKVNGATVHVGIHPSKVVIVKLKMDK DRKLILERKARSKQ-GKHSEESVTSPSATSVGGTVRQRKVPASGAGGAGMWRFYTEDSPG IKVGPVPVLVMSLLFIASVFMLHIWGKYTRGKREGKKKNVANEVVTREYTINIHKRIHGM GFKKRAPRAIKEIKKFAQKQMGTMDVRIETRLNKHMWSKGIRNVPYRVRVRLARKRNEDE DSPHKLYTLVSYVPMVNFKGSQTVNVESSSKSEFLVNGKYRLVRKIGSGSFGDIYLGINI ANGEELAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWFGEKEYNVLVMDLLGPSLE DLFNFCGRRFSMKTVLMLADQMIGRIEYVHNKNFIHRDIKPDNFLMGIGRHCNKVFLIDY GLAKKYRDNHTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGNVLMYFNRGS LPWQGLKAGTKKQKYEKISEKKMSTPVEVLCKTFPAEFAMYLNYCRGLRFEEAPDYMYLR QLFRILFRTLSHQYDYVFDWTILKQKTAAGMNAEKLKQRIGGKGSARRKKKVVHKSNVTD DKKIQMVLKKIGVNNIPGIEEVNMIKDDGDVIHFNNPKVQACLQSNTFAVTGHCETKSVT DLLPSILSQLRPDSLTALKKMASKLGTIE-DDDEVPELVENFDEASKTEMTRYSLNPENA AKSAKARGSHLRVHFKNTRETAQNIKHMHLRRAVAYLKNVIDHKECVPFRRFTGGVGRCA QAKAWGTTQGRWPKKSAEFLLQMLKNAESNADFKGLDTDHLVIEHIQVNRAPKMRRRTYR AHGRINAYMSSPCHIEIILAEREQAIEKPKKKKVSQKKLKKQKMMMREKKSGPKLELTEE QKQEIKEAFDLFDTEGTGTIDTKEIKVAMRALGFEPKKEEIKKMIADIDKEGTGRLDFND FMTLMTSKMNEKDYKEEIMKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQEADRD GDGEINESEFFRIMKKTSLYMGISRDKWHKRRKTGGRMSQVRKKRKFELGRPPAHTKIGA RRIHTIRTRGGNKKYRALRLDTGNFSWGSEAITRKTRILDVVYNASNNELVRTKTLVKNC IILIDSAPFRNWYEGHYALPLSRKKGVKLTPEEEARLNKRSKKAQRKYEIRKKTAKVEPA LEEQFASGKILACISSRPGQCGRADGYILEGKELDFYNRKIKAKKGKMSLVLPERFQHIL RVMNTNIDGKRKVPFALTAIKGVGRRYAHVVCKKANVDVTKRAGELTEEEVEKLVTIMGN PRQYKIPDWFLNRQKDIKDGKYSQAMSNILDSKIREDLERLKKIRAHRGLRHFWGLRVRG QHTKTTGRRGRTVGVSKKKDSATDSDGEESIHELEELAQAAGLNEEPVSKAKQSRSEKKA RKAMSKFGLKPIPGVSRVTVRKSKSILFVINRPDVYKSPVSDTYILFGEAKIEDLSQQAQ MAAAEKFKTEENVDETGVEAKDIELVMSQASVSRKKAIKALKRNQNDIVNAIMMGRVRTK TVKKASRVIIEKYYPRLTLDFHTNKRLCEEIAIIPTKKLRNKIAGFVTHLMRRIQKGPVR GISIKLQEEERERRDNYVPEKSAIDEICPDTKEMLKLIDMAHIPSLQVTTPIATAMRWEY KEENSFDKRKSEGDKIRKKYPDRVPVIVEKAPKARVEDLDKKKYLVPAELTVGQFYFLIR KRIHLKPEEALFFFVNNIIPPTSTTMGQLYQEHHEEDAFLYIAYSDESVYGMRDIRILKL CLNICVGESGDRLTRAAKVLEQLTGQQPVFSKARFTVRSFGIRRNEKIAVHCTVRGAKAE EILDKGLKVKEYELRKVNFSETGNFGFGIQEHIDLGIKYDPNIGIYGMDYYIVLGRPGYN VSKKRRAVGKVGPQHRVTKEEAIKWFQQKYDGVILPGKMGIKFLEFVKPFCAVLPEVQKP ERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGIS PIVTSGLIMQLLAGVKIIEVGDTPKDRALFNGAQKLFGMVITVGQAIVYVMTGMYGAPSD IGAGVCLIIIIQLFVAGVIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVN TGRGTEFEGAVIALFHLLATRQDKVRGLREAFYRQNLPNLMNLLATVFVFGVVIYFQGFR VDLPIKSSRYRGQYSSYPIKLFYTSNIPIILQSALVSNLYIISQMLSAKFSGNFIINLLG VWGDVGGGGPARSYPIGGLCYYLSPPETLQHVLEDPLHAILYIAFMLGSCAFFSKTWIDV SGSSAKDVAKQLKDQQMIMRGHREASMIHELNRYIPTAAAFGGLCIGALSVMADFMGAIG SGTGILLAVTIIYQYFEIFVKEQSE--GMGSLFFQVERAFQKQPTIFLNKKGT--QRYYK NVGLGFKTPREAIEGHYIDKKCPFTGNVFIRGRILTGVVLKMKMQRTIVIRRDYLHYVSK YERFEKRHKNLSVHLSPCFRDVQIGDIVTVGECRPLSKTVRFNVIKVTKGTGSKKAFAKF MVNVPKQRKTFCRGKKCRKHTLHKVTQYKKGKDSLFAQGKRRYDRKQSGYGGQTKPIFHK KAKTTKKIVLKMECTECKYRKQLAIKRCKHFELGGDKKKKGQMIQFMGRVIRSQRKGAAG IFKAHTKHRKGAAQLRAVDYAERHGYIKGVVKDIIHDPGRGAPLAKVVFRDPYRYRLRTE TFIAAEGMHTGQFIYCGKKATLQVGNILPLDSLPEGTSVCCLEEKMGDRGRLARTSGNCA VVISHNPETKRSRVKLPSGAKKLLPSSNRAMVGIVAGGGRMDKPMLKAGRAYHKYKAKRN CWPRVRGVAMNSVEHPHGGGNHQHIGKPSTVARDKSAGRKVGLIAARRTGRLRGTKQAVG KAKRTKKVGICGKYGTRYGASLRKDIKKMEITQHGKYTCSFCGKETMKRKAVGIWTCKSC KKVVAGGAYIYSTTAAATARSTIRRLKESKDMGRRPARCYRYCKNKPYPKSRFCRGVPDP KIRIFDLGRKKAKVDEFPLCVHLVSDEWEQISSEALEAGRICANKYLVKHCGKDAFHLRV RLHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVDIGQIILSVRAKDAHKDKVI EALRRAKFKFPGRQKIHVSRKWGFTKWDREKFEPMRAEGTLVPDGCDVQYKPPHGPLSAW MAAQQVTKILGRTGSQGQCTQVRVEFIDETNRSIIRNVKGPVREGDILTLLESEREARRL RMTKGTSSFGKRHNKTHTLCRRCGGRCYHIQKQTCARCGYPAKRMRKYNWSEKACRRRTQ GIGRMKHLKKVFRRFRNGFREGGVAKKVKAMVEDRAAAKELDQWIEQLMDCKQLAENNVK TLCDKAREILSKESNVQEVKCPVTVCGDVHGQFHDLMELFKIGGKSPDTNYLFMGDYVDR GYHSVETVTLLVALKVRFKDRITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDNQIFCLHGGLSPSIDTLDNIRALDRIQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHSNGLTLVSRAHQLVMEGYNWSHDKNVVTVFSAPNYCYRC GNQAALCELDDSLKYSFLQFDPAPRRGEPHVTRRTPDYFLMGAYKYMQELYRKKQSDVLR FLLRIRCWQLRQLAAVHRASRPTRPEKAKRLGYKAKQGFVIYRVRIRRGGRKRPAPKGQV YGKPKSVGINQLKNQRSLQAVAEERVGRKCKALRVLNSYWIGQDSTYKFFEVICVDPFHN AIRRDKAIQWICKPVAKHREMRGLTSANRKSRGLGKGHGYSKTIGGSRRANWKKNNTIEM HRKRGIAIGRLSEERKAWRKDHPFGFVARPTKAPDGTLNLMNWECGIPGKKTTPWEGGLY KLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSLLDEEKDWRPAVTIKQILLGIQE LLNEPNVKDPAQAEAYTIYCQNRAEYERRVREQALRFRDPSLGRSSKMLQHINYRMRCTL QDGRIFIGTFKAFDKHMNVILGDCDEFRKIKSK-NKAKEEKRTLGLVLLRGETLVTMTVE GPPPPEEGLARVPVPGSAGGPGVGRAAGRGMPI-LGLAGPARGIGMPPSQMMQPQPGMMR GGPPDDMPSFKLVLVGDGGTGKTTFVKRHLTGEFEKKYIATLGVEVHPLVFHTNRGPIRF NVWDTAGQEKFGGLRDGYYIQGQCAIIMFDVTARVTYKNVPNWHRDLVRVCENVPIVLCG NKVDVKDRKVKAKSITFHRKKNLQYYDISAKSNYNFEKPFLWLARKLTGDQNLEFVAMPA LAPPEIEMDPSMANKYEEELKIAQSTALPDDDDDISEGLKQYYVTKIEELQLIVAEKIQN LRRLEAQRNELNAKVRLLREELQLLQESGSYVGEVVKAMDKKKVLVKVHPEGKFVVDIDK NIDITDVTPNCRVALRSDSYTLHKILPNKVDPLVSLMMVEKVPDSTYENVGGLDKQIKEI KEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ KFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSARLEGGSGGDSEVQRTMLELLNQLD GFEPKQNIKVIMATNRIDILDSALLRPGRIDRKIEFPAPNEEARLDILKIHSRKMNLTRG INLRMIAEMMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFELAVAKVMQKDSEKNMSI KKLWKLSFYENFLLSGAAAIISKTAAAPIERVKLLVQNQGEMIKMGRLDRPYNGVIDCTV RTFKTEGILPFWRGNLANCIRYFPTQALNFAFKDKIKALFVMNKKDPYMVNFSKNVASGG VAGAMSLVFVYSLDYCRTRLANDAKASKKRQFNGMVDVYRKTIASDGVVGLYRGFVISCV GIIVYRGCYFGFYDTLKPIVLGDNAGLMISFALGYIVTITSGLISYPIDTIRRRMMMTSG EAVKYKGSIDCAVKVVKSEGFMSLMKGAGANILRGVAGAGVLAGFDKFKALYVKWRVMSA VSDLDRQIEQLQKCEIIKESEVKALCARAREILIEESNVQRVDSPVTVCGDIHGQFYDLQ ELFKVGGDIPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRIMLIRGNHESRQITQV YGFYDECLRKYGSVAVWRYCTEIFDYLSLSAIIDDTIFCVHGGLSPSIQTLDQIRAIDRK QEVPHDGPMCDLLWSDPEDTQGWGVSPRGAGYLFGSDVVQQFNTSNNIELICRAHQLVME GFKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLKRNFTIFEAAPQEQRGKPQADYFL VRLPPEVNRILFIKNLPYKITAEEMYDIFGKYGAIRQIRVGNTTETKGTAFVIYEDIFDA KNACDHLSGFNVCNRYLVVLYYQPNKQYKKTDVQKKAEELDNMKEKYGLSTPEFKMSIGV PIKVLHEAEGHVVTCETNTGEIYRGKLVEAEDNMNCQFAGVTVTYRDGRTMELENVYIRG SKVRFLILPDMLKNAPMFKKVGAGRGKSAILRAAARGRGRSFSGSNRGGMQNDAGEYVDM YIPRKCSASNRIISAKDHAAIQINLAEVDEQTGRMTGQNKTYAICGNIRRMGESDDCLNF LCKRDSILPKMVRGPRKHLKRVVAPKHWMLDKLGGVFAPRPSCGPHKLRECLPLVIFLRN RLKYALTYEEVKKILKQRLVKVDGKVRTDKTYPAGFMDVISIERTNENFRLIYDAKGRFA VHRIQSEEAKYKLCKVKKILIGLKGIPSLVTSDGRTIRFPDPLIKVNDTVKVMSGREDEY DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIMVDNKRIKAQIWDTA GQERYRAITSAYYRGAVGALVVYDIAKHMTFENVERWLKELRDHADDNIVIMLVGNKSDL RHLRAVPTDLAKSFAEKNSVSFLETSALDSTNVEAAFTHILTAIYKIVSQKHMADTGDDY NAQAITIPPTSTLDKKNSSCCSMTSSYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVAVR GTNVVVLGVEKKAVAKLQEDRTVRKIALLDDHVALAFAGLTADARILISRARVECQSYKL TVEDPVTVEYITRYIAQLKQKYTQSNGRRPFGLSTLIVGFDGTPRLYQTDPSGTHFEWKA NAIGRSAKTVREFLEKNYSEEVASDRETIKLAVKALLEVVQSGSKNMEVAVMRKDQPLEI QNTDVIDELIKEIEKEKEEENEKKKKKGG-HHGDKKDDKDKKKKYEPPVPTRVGKKKKRI KGPEAANKLPQVTPHTRCHLKLLKLERIKDYLLMEEEFIKNQERLKPQEEKQEEERSKVD DLRGTPMSVGSLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDQLEPGCSVLLNHKVHAVV GVLSDDTDPMVTVMKLEKAPQETYADIGGLDQQIQEIKESVELPLTHPEYYEEMGIKPPK GVILYGAPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPS IVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSKGDVKVIMATNRIETLDPA LIRPGRIDRKIEFPLPDEKTKRRIFTIHTGRMTLAEDVNLEDYIMAKDDLSGADIKAICT EAGLLALRERRMKVTNEDFKKAKENVLYRKNEGSPEGLYLERKPYSPFQVPNAADYVLAR LDDIINWGRKSSLWPMTFGLACCAIEMMHFAAPRYDMDRFGVVFRASPRQADCMIVAGTV TNKMAPALRKIYDQMPDPRWVISMGSCANGGGYYHYSYSVVRGCDRLIPVDIYVPGCPPT AEALLYGVLQLQKKIKRMKTTQIWYRKSNFYLRYYVGHRGKFGHEFLEFEFRPEGKLRYA NNSNYKNDVMIRKEAFIHKSVMQELQRIIEDSEIMQEDDNLWPQPDRVGRQELEIVMDDE HISFTTSKIGSLMDVNQSSDPEGLRTFYYLVQDLKCFVFSLIGLHFKINPIMVAQKKTKK AIESINSRLALVMKSGKYFLGYQQTLKTLRQGKAKLVIIANNTPPLRKSEIEYYAMLAKT GVHHYNGNNIELGTACGKYFRVTTLSITDPGDSDIIRSMPTTMTEYKLVVVGAGGVGKSA LTIQLIQNHFVEEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGF LCIFAVNNCKSFEDINQYREQIKRVKDADEVPMVLVGNKVDLSSRTVDTKSAKDKADSYC IPYVETSAKTRQGVDDAFFTLVREIRKYMGDRYNIHSQLEHLQSRYVGTGHADTNKWEWM THQHRDSYASYIGRPDLLNFFAISENESKARVKFNFLERMLQPCGPPPERPEEMKIELCV FSGYKIYPGHGKRVVKVDGKSYQFLNGKCSKAHLVKRNPRKVHWTVLYRRKHKKGLTEEV TKKRTRKTTKFQRAITGASLSDIIAKRNQKPEVRQAQREQAIRAAKEKAKAKEKSQPRVG GKRMKLNISCPATGCQKLIEVDDERKLRAFYDKRLTAEVNAECLGDEWKGYVVRISGGND KQGFPMKQGVLTNGRVRLLLKDGHSCYRMRRSGERRRKSVRGCIVDANLSVLSLVIIKKG EQEIPGLTDTTIPRRLGPKRASKIRKLFNLDKKDDVRQYVVRRPLPPVFRAPKIQRLVTP LVLQRKRHRLALKRKRIIKRREDKAEYQKLLAQRIKEAKERKMERRRSASHSKKVKAKDL RNKKKDELLKQLDELKTELSQLRVAKVTGGAASKLSKIRTVRKSIARVLTVIHQTQKENL RKFYKPKDLRKKLTRAMRRALTPHELGIQTAKELHKKLAYPQRVYAIKSAEKGPKVTDKV FFDIEIGGEKQGRIVIGLFGKTVPRTVKNFKTIAEGTESYKGSKFHRVIKDFMIQGGDFN KGDGTGGLSIYFPDENFKLKHYGAGWVSMANAGKDTNGSQFFITTKATDWLNGRHVVFGV VLEGMKVVRLIENVKKDRDKPLDDVVIADCGSLPVEEPFAVPKESAKERKKKTSLKYTLD CTHPVEDGIMDCANFEKFLLEKIKVNGKTGNLKSKVVVNSEVPFSKRYLKYLTKKFLKKN NLRDWLRVVANSKDSYELRYFQINNEEEDEEDEKKASPNNQDDSKYGGCEGPEAMYVKLI SSDGHEFIVKRDHALTSGTIKAMLSGPGQFAENETNEIHFKEIPSHVLQKVCMYFTYKVR YTNSSTEIPEFPISAEIALELLMAANFLDCTKIYKLADVKSHNNSKSCWIIIHNDVYDVT PFLEEHPGGEEVLLEQAGSFASEAFEDVGHSTDAKEMMKQYKIGTLHESDRTSWTSWLIP LAIAAAIAFFYRYFMSYMLQHLKNGWQVDQAILSEEDRVVIIRFGHDWDPTCMVMDETLY NVAERVKNFATIYLVDITEVPDFNKMYELYDPCTVMFFYRNKHIMIDLGTGNNNKINWAM EDQQEFIDIIETIFRGARKGRGLVVSPKDYSTKYRYQKLQKQLEFLEVQEEYIKDEQKNL KKEYLHAQEEVKRIQSVPLVIGQFLEAVDQNNGIVGSTTGSNYYVRILSTIDRELLKPSA SVALHKHSNALVDVLPPEADSSITMLSADEKPDVSYSDIGGMDIQKQEVREAVELPLTHF ELYKQIGIDPPRGVLMFGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVR DVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTVNVKVI MATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITGKMNLSDDVDLEDYISRPD KISGADINAICQEAGMQAVRENRYVVLPKDFEKGYKNNTKKDEQEHEFYKSHVPLTLDMV NQRVLLVLRLYDKINPDKLTLESHFINDLGLDSLDHVEVIMAIEDEFGFEIPDSDAERLL TPAHIVQYIADKEDLERRKQT-VEDLKNVEFESSEDVDVLPTFDMMGLRPELVRGIYAYG FEKPSAIQQRAIKPIVKGRDVIAQAQSGTGKTATFSIAILQNIDTQIRETQALVLSPTRE LAQQIQKVLLALGDYMSVQCHACIGGTNVGEDLRKLDYGQHVVSGTPGRVFDMIKRRTLR TRSIKLLVLDEADEMLNKGFKEQIYDVYRYLPPAIQVAIISATLPHEILEMTSKFMNDPV RILVKRDELTLEGLKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKM RENNFTVSAMHGDMPQKEREAIMQEFRTGASRVLITTDVWARGIDVQQVSLVINYDLPNN RELYIHRIGRSGRFGRKGVSINFVKHDDIRILRDIEQYYSTQIDEMPMNVADLILSIRRP FDPQIHDLDPNFRLTRFADLKGGCKVPSDALTRMLEPFRELLDSEQSHFQYVAATPRIGI GMDACITPIRHGGLSLVQTASCLYPIIDDPYMLGKIVGSAVMSNLFAMGVTECDNMLMTL SISQKMTDRERDVVVPLIMSGFKDCAEEVGVTVNGGQTIVNPWMYLGGVATSVCQSNEYI MPDNAMIGDVLVLTKPLGTLVAANAYQWLDVNEKWNRIKLVVGEEDVRKAYQRAMFSMAR LNRIAALLMHKYNAHGATDIGGYGLLGHANKLAGIQKNEVGFVIHNLPVIAKMAAVSKAC GNMFGLLQGHSAETSGGLLISLPREQAAAFCKDIEKQEGYQAWIIGIVEKGNRTARIIDK PRVIEVPAKDKEFFTLILEYVAGYYITIDAHAEECYFDRVSSGTKLSLMFEVAEGGFLDI DVHITGPDGKQIYSGERESNGKFTFAAHQDGDYKYCFSNKMSTMTPKVVMFTMEIGEKAK TTQNKLEEMISELSSKLYGVKHEQEYMEVRERIHRAINDSTNSRVVLWSFFEALVLVAMT LGQVYYLKRFFEVRRVIMSATLQPYLKAVRNTLTAAICVENFSSQVVERHNKPEVEVRTS KELLLTPVVISRNEKEKVLIEGSINSLRISIAVKQADEIEKILCKKFMRFMMMRADNFVI LRRKPIEGYDVSFLITNFHTEQMYKHKLVDFVINFMEEIDKEISEMKLALNSRARISAEE FLKRFSRRKTLLKVIILGDSGVGKTSLMNQFVNKKFSNQYKATIGADFLTREVMVDNKLV TLQIWDTAGQERFQSLGVAFYRGADCCVLAFDVTVASTFKNLDSWRDEFLIQASPRDSEH FPFVVIGNKIDLENRAVTAKRAQQWCEMKNHAPYFETSAKDAIGVEQAFQTVARNALAQE ADSEMYNEFPEPITLTGNPGGSNCSCTPPFDARFPNANQTRNCWQNYVDFHRCQKIEDYA PCEYFKKVYKSLCPNEWISRWDDQREKGAFPARIMKDYLGKDQRKTVDDNEDDKPIQVLD EGDIALLKTYGVGMYYKSIKSTEDDIQGILKRVNELTGIKESDTGLAPPAHWDLAADKQT LQSEQPLQVARCTKIINADSDDPKYIINVKQFAKFVVDLSDHVAPTDIEEGMRVGVDRNK YQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVEVPLLHPERFVNLGI EPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMART KKACIVFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDT LDPALTRPGRLDRKVEFGLPDLEGRTNIFKIHARSMSVEKDIRYELLARLCPNSTGAEIR SVCTEAGMFAIRARRKMATEKDFLEAVNKVIKAYAKFSATPRYMTYNMPAEKTHINIVVI GHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITI DISLWKFETSKYYITIIDAPGHRDFIKNMITGTSQADCAVLVVAAGVGEFEAGISKNGQT REHALLAYTLGVKQLIVGVNKMDSTEPPYSEARFEEIKKEVVAYIKKIGYNPDFVPFVPI SGWNGDNMLKMPWFKGWSVYSGVTILDALDNIDPPKRPTDKPLRLPLQDVYKIGGIGTVP VGRVETGIIKAGMIVTFAPVNLTTEVKSVEMHHQALEEAQPGDNVGFNVKNVSVKDIRRG NVAGDSKNDPPKETEEFKAQVIIMNHPGQIGPGYAPVVDCHTSHIACKFRDLLEKIDRRS GKKLEDNPAHVKAGDAAIVEMVPQKPMCVESFSEYPPLGRFAVRDMRQTVAVGVIKSVKK REGGQAKVTKAAQKAELEQLRQEAEQLKNQIREARKAMADTSLAQMTANMEPVGRIQMRT RRTLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDGYTTNKMHAIPLRSSWVMTCAYAP SGNYVACGGLDNICSIYSLKTREGNVRVSRELSGHNGYLSCCRFLDDNQIVTSSGDMTCA LWDIETGQQTTSFSGHTGDVMSLSVAPDMRSFVSGACDASAKLWDIRDGMCKQTFTGHES DINAITFFPSGYAFTTGSDDATCRLFDTRADQEIGMFSHDNIICGITSVAFSKSGRLLFG GYDDFNCNVWDSLKQDRAGVLAGHDNRVSCLGVTEDGTAVATGSWDSFLKIWNMSYAYLF KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMIGIDGKQIKLQIWDTAGQES FRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARR DVKKEEGEAFAREHGLIFMETSAKTAANVEEAFINTAKEIYQKIQEGVFDINNEANGIKI GPQHFQANAVGGGGSGQSGGMKKGVIELGDVTSHNIKQLRRINEVVFPVVYNDKFYKDIL EVGELAKLAFYNDIVVGAVCCREDKMDGQKRLYIMTLGCLAPYRRLGIGSIMLEHILNIC QTDGLYDNVYLHVQISNSSAISFYEKFGFKIVETKENYYKKIEPADAYVLQRSFKEMPKQ IQEIKDFLLTARRADAKSVKIKKNVKFKVRCSRYLYTLVINDNEKADKLRQSLPPGLQVK DLKFSKISRDSLAESVAALLTKKRKFTETVELQISLKNYDPQKDKRFSGTVKLRNIPRPK MAICVLGDQQHCDEAKANSVECMDAEALKKLNKNKKLIKKLAKKYDAFLASDSLIKQIPR IVGPGLNKAGKFPSMLTHGESMTGKIEEVKATIKFQMKKVLCLSVAVGNVNMTQDELVSN ITMAINFLVSLLKKNWQNVRSLYIKSTMGPVQRLYMADADKLNIDSVIARLLEVRGSKPG KNVQLTDNEIRSLCLKSREIFLSQPILLELEAPLKVCGDIHGQYYDLLRLFEYGGFPPES NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKEVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYAGVQGSRPVTPPKGTAKGK GKMMFRNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDGDIQSLVLEIIGTNVSTT FITCPCDPKKTLGIKLPFLVMIIKNLKKYFTFEVQILDDKNVRRRFRASNYQSTTRVKPF ICTMPMRLDEGWNQIQFNLSDFTRKAYGTNYIETLRVQIHANCRIRRLYFSDRLYSEEEL PAEFKLFIPVMGKMTDSVIQNLQDPFAEDESIHIRIQQRNGRKTLTTVQGVSSEFDLKKI VKVAKKEFACNGTVVEHPEYGEVIQLQGDQRQNISKFLKQVGLDDQIKVHGFSAIFNFQS LLTVVLLLICTCAYIRSIAPSLLDKNKEGLLGVFWKCARIGERKSPYVALCCVAMAFSIL FLSSSRIASLAVRQLPKSITEKHALGAGFVACRKLSTTAEISSILEERILGTTAVNLEET GKVLSIGDGIARVYGLKNIQAEEMVEFSSGLKGMALNLEPDNVGIVVFGNDKLIKEGDIV KRTGAIVDVPVGAELLGRVVDALGNPIDGKGPIK-AKRARVGVKAPGIIPRISVREPMQT GIKAVDSLVPIGRGQRELIIGDRQTGKTAIAMDTIINQKRFNDGQNEKSKLYCIYVAIGQ KRSTVAQIVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCAMGEYFRDNGKHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDTFGGGSLTALPVIE TQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQMRAMKQVAG SMKLDLAQYREVAAFAQFGSDLDAATQALLNKGVRLTELLKQGQYCPMAVEEQVCVIYAG VRGHLDKVDPSRITAFEVKFLEHLRSSQQDLLKAIREAGKLTDETDAQLKKVVIDFLAGF MESLYNVPYSFLECPNLKLKKPTWLHTPSAMFVFSLVLVSYFLVTGGIIYDVIVEPPSIG STTDERGNSKPVAFMQYRVNGQYIMEGLASSFLFSMGGLGFIILDQTNKPSTPRLNRILL LSIAFICILVSFFMCRVFMRIKLPMPKVKRSRKPPPEGWELIEPTLEELDQKMREAETDP HEGMRKAEALWPIFRIHGQKSRYIFDLFYKRKAISRELYEYCLKEKIADANLIAKWKKTG YENLCCLRCIQTQDTNFHTNCICRVPKSKLEEGKIVECVNCGCRGCSGEYAQVTKMLGNG RLEATCFDGSKRLCHIRGKLRKKVWINGGDIILVGLRDYQDNKADVILKYTPDEARNLKA YGELPESAKINEDMDDNVLFDDIDDVIFRFLMKLSHETVTIELKNGTQVHGTITGVDVSM NTHLKSVKMTAKNKDPVPLETLSIRGNNIRYYILPDSLPLDTLLIDDTPKGRGRGSTIQK PKSEMTPEELAQKEQEEFNTGPLSVLTLSVKNNTQVLINCRNNKKLLGRVKAFDRHCNMV LENVKEMWTEVPKTGKGKKKSKPVNKDRYISKMFLRGDSVILVLKNPLPIIIDARGHLLG RLAATTAKSILQGQKIVVLRCEGINISGNFYRNKLKYLDFLKKRMNTNPSRGPYHHRAPS KIFWRTVRGMLPHKLHRGKEALDRLKAFEGVPPPYDKQKRFVVPSALRIIRL-PRRKFCQ LSRLSHEVGWKYQGVVATLEKRRKLKSSLYFKKKICEKKLMEQAKKVPQYQKIIESYGHA GDVEKGKKLFVQRCAQCHTVEAGGKHKTGPNLHGLIGRQTGLASGYTYTDANKSKGIKWT QDTLFEYLENPKKYIPGTKMIFAGLKKEQERADLIAYLESATKITIEKTLAIIKPDAFEY EILDTILRNGFFVLNKMKIHLSPEQASEFYEEHYNKSFFSRLIHYISSGYIIVLVLGKQN AVLDWRNLIGPTDSEKARESHPHSLRALYGKDKEVNAFHGSDSLESAKREIKFFFPNLVE EPVALENDARYFMQKYVNPTLLKGLTALCHKKPENPVVWLADWLTNNNPNKPRIQMFEAR LVQGSLLKKVLEAVKDLLNEATWDCNGTGMSLQAMDSSHVSLVSLCLRSDGFDTYRCDRN ISMGINLGSMSKILRCAGNEDAITVKANDTTDTITFMFESPNGEKVSDYEMKLMDLDTEH LGIPETDYSCVIKLPSSEFQRICRDLSQIGESVVICCTKEGVKFSANGDLGTGNIKLAQS ANVDKEDEAVVIEMQEAVTLTFALRYLNFFTKATPLSARVSLSMSADVPLVVEYKIGDMG YIRYYLAPKIEDNEDAKSAACLHTTSKIAKGKIVAVIGAVVDVQFDDELPSILNALEVEN RKPRLILEVAQHLGEKTCRTIAMDGTEGLIRGQVCTDTGAPIRIPVGPETLGRIINVIGE PIDERGPVNAKHFAEIHADAPEFVEMSVEQEILETGIKVVDMLAPYAKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIMSGVIDLKGDKSKVSLVYG QMNEPPGARARVALTGLTVAEYFRDKEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIA ELGIYPAVDPLDSTSRILDPNIVGQEHYSVARGVQKILQDYKSLQDIIAILGMDELSEDD KLTVARARKIQRFLSQPFQVAEVFTGSEGKLVPLKESIKGFKMILNGEMDHLPEVAFYMV GPIEEVIQKADRLAEERMLMPKKNRVLIYEHLFKEGVLVAKKDFHAPKHTEIDVPNLHVI KALQTLVSKGFVTEQFCWRHYYWYLKNEGITYLRDFLHLPPEIVPSTLKRQQVGEDRAAY RRG-GSDKKGEAGAGANMGKEQSKLKPEALEDLRKNTAFTDDEIQEWYRGFMKDCPSGKL SKEEFKKIYANFFPSGDASMFSGHVFRTFDTNNDGTIDFREFLCALSITSRGNLEQKLKW AFNMYDLDGNGFISKREMLEIVSAIYKMVGSTMKMPEDESTPEKRTDKIFRQMDKNLDDK LSLKEFIDGAMNDSTIVQLLQCDPMSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNL TGLNEQVPHYRQAIDMILDLEPEDNLDDNPNQSDLIEQAAEMLYGLIHARYIMTNRGIAQ MIEKWQQGEFGYCPRVYCENQPTLPIGLSDVPGESMVKLYCPKCQDVFVPKSSRHHHTDG AYFGTGFPHMLFMVHPEYRPKRPTNQFVSRLYGFKIHPLAYELQTQAANNFKSSYANNKR MTNSGGYRRGTRHLFSRKFRKRGVIPISTYLKTYKRGDMVDIKGNGAVQKGMPHKSYHGR TGVVYNVTPHAVGVIVNKRVKGRILPKRVNIRVEHIKHSACRQEFLKRVAENERKKREAK EVVFCKRQPEQPRPGHFVSTKYNKPIILEPIPYEFLAATRTHYKQVSPEDPVMEWKELTD RAANKAFFIELMKGMNIVMSQLFKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAVCPAQAITIEAETRADGSRRTTRYDIDMNKCIFCGFCQEACPVDAIVEGPNFEY STESREELMYNKEKLLANGDKWEVEIAANLQADHLYRMAAQPKVAKVEGKNKKDADKEQQ EAIEKIDEVQNEIDRLNEQASDEILKVEQKYNKLRQPFFQKRSEMIAKIPNFWVTAFVNH PQVSALLNDEDEEVFHFLTKVEVQEFDDIKSGYKITFHFKENEFFKNQTISKEFHLNSSI STPINWKNGKDLVKKYRKRNHEDPESFFSWFSDNSDAGVDELGEVIKDDIWPNPLQYYLA SEMDEDHS-DDGVDDDEKKLTKQEELLLQDFSRNVSTKSSALFYGNAFIVSAIPIWLFWR IHQIDMYILFLIFTSVSTYLVALAYKNVKFVLKHKIAIKRGEAVNREVMRQIADDKKMSK QEKEERVLWKKNEVADYEATTFSIFYNNALFLVLVIVASFYLLRSFSPYVNYSLSMVTAS GLLALFSTSSKSTQPKACQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQT IVLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIIVYDITSQDTFLRATNWVKELQRQ ASPNIVMALAGNKSDLRMVEYADAQQYAEENNLLFMETSAKTAANVNDIFLAIAKKLPKS DPSVDLSQANMAEYLASIFGTEKDKVNCSFFFKIGACRHGDRCSRLHNKPTFSQTVLLQS LYNNPLNTATSGIEEAQNQEEYDNFFEEVFTELEEKYGRIEEMNVCDNLGDHLLGNVYVK FESEEIAERAVADLNNRWFNGRPITAELSPVTDFREACCRQYELGECTRGGFCNFMHLKP ISRELRRELYGRSKRSRSRSPPTRRGTHERD-RRRRRSRSRSRDRMFLTRSEYDRGVNTF SPEGRLFQVEYAIEAIKLGSTAIGIQTPEGVVLAVEKRVTSPLIEPSSIEKIFEIDSHIG CAMSGLVADSRTMIDKARMEAQHHWFTYNEKMKVESVTQSVSNLALQFGDDDADPGAMSR PFGVALLIAGIDELGPQLFHMDPSGTFIQYDAKAIGSGSEGAQQALQEIFYKDMKLENAC VEILKILKQVMEEKLNATNIEMATITKEHNFKLLDKDELQRFIDRIAYMTWELSNKIEAL SGADEIYHYDEKQQKDILAAKPWEKDPHYFNSIKISALALLKMVMHARSGGNLEVMGLLL GKVDINNMIVMDSFALPVEGTETRVNAQAQAYEYMAAYIDAAKQVGRLENAIGWYHSHPG YGCWLSGIDVSTQMLNQQFQEPFVAIVIDPIRTISAGKVNLGAFRTYPKGYKPPDDGPSE YQSIPLNKIEDFGVHCKQYYPLDVSYFKSSLDRRLLEMLWDKYWVNTLSSCNLLTNADYT TGQIYDLTDKLEQSESFLGRGPFVADRAEDKLTKATKDSCKNTIESIHGLMTQVIKDKLF NKIGGLPRRILKETQRLKAEPVPGIEATPDENNARYFHVIVVGPKDSPYEGGVFKLELFL PEEYPMSAPKVRFMTRIYHPNIDKLGRICLDILKEKWSPALQIRTVLLSIQALLSAPNPD DPLANDVAEQWKVNEAQAIETARQWTRRYAADNDELLDYEEDEQEEIKELKGTYVSIHSS GFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGLDVVCQAKSGMGKTAVFVLATLQ QLEIVDKQVSVLVMCHTRELAFQISKEYERFSKYMNGVKIAVFFGGMAITKDEATLKNNC PHIVVGTPGRILALVKNLDLKHLKHFILDECDKMLDQLDMRRDIQEIFKVTPHEKQVMMF SATLGKDIRPVCKKFMQDPMEVYVDDDSKLTLHGLQQHYVKLKDNEKNRKLFELLDALEF NQVIIFVKSIQRCVALSQLLVEQNFPAIAIHKAMSQDDRLSRYQQFKDFQSRILVATNLF GRGMDIERVNIVFNYDMPENSDTYLHRVARAGRFGTKGLAVTFVSDETDAKVPPSFADLG KSARDLFSKGFHFGFFKVEAKTKTNGGVEFTTGGSSSHDTGLFSGSLESKYKWKEHGATL KETWSTDNALAGELTVEDQLLEGLKLGFETKLFIASGKKSGKVKTAYKNDLVHTT--LDF DVMTYGLLGSIVFGHNGFLGGFQLNYDKSLMSQSNVAIGYSKDDLDLFVGVKGCNEYSSS VFHKIHDDLETGIHLSWLSGTNETAFGFGAKYNIDRDATIKAKVDNSSRVGLSYQQKLRP GVTLTLSTLVEGKTFTAGGHKFGCALEFEANSVRDKILQDYRKKLLDHKELEARLKEMRE QLKELTKQYDKSENDLKALQSVGQIVGEVLKQLTEDKFIVKATNGPRYVVGCRRQLDKTK LKPGTRVALDMTTLTIMRYLPREVDPLVYNMSTEDPGNISYSQIGGLSEQIRELREVIEL PLMNPELFQRVGITPPKGCLLFGPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIGES ARLIREMFGYGRDHQPCIIFMDEIDAILKEHQLIEKSRELSWRQACLLNQMDGFDALGQV KIIMATNRPDTLDPALLRPGRLDRKIEIPLPNEQARLEILKIHAGPIAKHGEIDWEAIVK LSDDFNGADLRNVCTEAGMFAIRAERDFVIEEDFFKGVRKIADNKKLETKLEYKPVMADT LTGVLKRFYDDYSLSTSKKLKIVDAYLLYILLTGAIQFLYCCLVGTFPFNSFLSGFISCV GSFVLAVCLRVQVNPVNKDVFHGLSPERAFADFIFAHVILHLVVINFIGSLANPSQLLPL ELVDKCIGSKIHIIMKNEKEIVGTLLGFDDFVNMVLEDVTEFETTPEGRRITKLERILLN GNNITMLIPGGEGPDVIDHYENPRNVGSFDKKEKNVGTGLVGAPACGDVMKLQIKVDENG KIVDAKFKTFGCGSAIASSSLATEWIKGKTLNEAGKITNAEIAKELCLPPVKLHCSMLAQ DAIKAALSDYNKKNKMLVLIISDLHIPFRSNGIPVQFRKLLVPGKIQHILCTGNLCSREM FDYLKTLANDLHIVRGDFDDNLYLPEQKVVMVGKFKIGLCHGHQIVPWADQESLLALQRQ LDVDVLVTGHTHKVEIFEQENKLFINPGSATGAYSSFESNIVPSFILLDVQANMIIAYLY QLIAGEVKVERTEFKKMGKFMKSGKVVLILGGKYAGRKAIIVKNYDDGTSEKQYSHALVA GISRYPLAVTKKMNKKKIKTRSKIKPFIRVYNYNHLMPTRYTVVNLDKQLVNKDAFRDPA LRSKARREIKAKFEERYKTGKNRWFFQKLRFERTFIMVKPDGVHRGLVGEIIKRFEQKGF KLVALKFVHASEDHLKKHYEALSSKPFFGGLVKYMSSGPLVPMVWEGNVVKTGRIILGET NPFDSKPGTIRGDFGIEVGRNICHGSDSVESAKIEVALWFHDAELLNWTPVATPWIYESA VPKPIKIDGKAKEKALKAKKAVTKGVHDKRSRKIRTSVHFRRPKTLSLERVPKYPRRSHV KKPSLDQYKVIKYPLTTESAMKKIEDNNTLVFIVDKRATKSKVKWAVKKLYEITASKVNT LIRMDGEKKAYVRLAPDFDALDVANKIGIIMAPKQKMRLANEKHSKNVVNRGNVPKTLKQ EDEKLPVGPWLLGLFIFVVCGSAVFQIIQSIRMVRFKGWTAVATWKWIANDDNCGICRMA FDGCCPDCKIPGDDCPLVWGQCSHCFHIHCIVKWLNSQQTHQICPMCRREWKFKEMIRFI LIQNRAGKTRLAKWYMHFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIVYRRYAGL YFCICVDITDNNLVYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYSIVDEMFLAGEIRE TSQTKVLKQLLMLSSLEKPTIFSKIIDKTIPAKLIYEDEHCVAFHDANPQAPVHFLLVPR KIITGLSEDKMLLGHMMTVVDKVAREDSGYRVVINNGPQGCQSVYHLHLHVLGGRQLGWP PMGGLFSYFSSLFGSVERRILILGLDGAGKTTILYRLQVGEVVSTIPTIGFNVETVQYKN LKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSMDRDRIGISKQELVSMLEEEELRKSV LCIFANKQDIEGSMTVTEVANALGLAAIKNRRYQIFKTSAIKGDGLDEAMEWLATTLQSS KGLYFHIGETQKKCFIEDIPDDTLVVGKYKVEIFDANISRFVPSLPGLGMHVEVKDVEDK TMLSRTYASEGRFSFTSHMAGEHLICLHANTSAWFGGHQLRIHLSIQVGERANDYQEIAS KDKLTELQLRVRQLLDQIEMISKEQNYQRFREERFRETSESTNQRVFWWAVAQLSILVVT GFWQMKHLKGFFEAKKLVMFFHVNLDHEILLHPRYFGPNLLQTVKQKLFSEVEGTCTGKY GFVVAVTTIDNIGVGLIQPGRGFVVYPVKYKAIVFRPFKGEVLEGIVTQVNKIGIFADIG PLSCFISKQSIPADMEFDSLSNPQCYKSKDEDAIIQVDDEIRIKIVGTRVDAKEIFAIGT LMDDYLGLINRLYAKAVFTGYKRGLRNQHENTALLKIDGVTNKKETDFYLGKRCAYVYRA KKKTACPNREKATHLRVIWGKVTRPHGSSGAVRAKFKSNLPPKAIGRRIRVVGYMAKKTY DLLFKLLLIGDSGVGKTCLLFRFSDDAFNTTFISTIGIDFKIKTVELGGKKIKLQIWDTA GQERFHTITTSYYRGAMGIILVYDITSLKTFENISKWLRYIDEHANADVEKMILGNKCDM EDRRQVPKEKGQEIADQHHIPFLETSAKSNVNVERAFLQLAQAILDKMPQNEYIELHRKR HGRRLDYEERKRKKESRKAQEDSRKAKKLRGIKAKLYNKKRHLEKIQMKKTIKMHEERDT KQKAPQDVPDGAQTYFLLDREMQNRAKVLSNTIKEKRKEKAGKWEVPLPRVSAVSEADMF RVVKTGKTRRKAWKRLITKVCFVGEGFTRKPPKFERFIRPTGLRQTKAHVTHPELKATFC LPIIGVKKNPTAPLYTQLGVITKGTILEVNVSDLGLITTGGKVVWGKYAQVTNNPENDGC INAVLLVMAYRPFISVYDEKGVATGTALPMPAVFRAPIRTDIVSTVHMDMLKNGRQPYAV STKAGHQTSAESWGTGRAVARIPRVSGGGTNRSGQGAFGNMCRGGRMFAPTKTWRRWHRH INVNQRRYAICSAIAATGIPAIVQSKGHLIDSVPEIPLVLSDKVQEIKKTKEAVGVLRKL KAWPDIEKVKNSKRFRAGKGKMRNRRRIQKRGPIIVYNQDNGITRAFRNIPGITLLSVDR LNLLKIAPGGHVGRFVIWTESAFKQLDPIYGTWKKASEHKTGYNLPAPKMTNTDLQRILK SDEIQKALRLPIKSRTKKVLKRNPLKNKEVMQKLNPFAIVQTKVAKQKLKKQALLDAKRG IATLDMGSKARPRKRIAGSGEEELASKTLQIQSKRFYLDVKQNRRGRFIKLAEVGAGGKK SRLLFAMSTAAEFRDLLTEFSDHYASLGPPNASKIPDDGKLKSEVMSKENRRYYLDLKEN QRGRFLRVSPLSRQRAQVAIPAQGMIEIRDSLTDLLNEFGTDDHETHEELPEPQSLKAEN KIFYFDIGQNRRGKFMRISETNFRTAITIPERSWARFRDVLSDFADKEKKREHQIKVKAT INQKLIESGERERLKELLRTRLIECGWRDQLKLHCKEIVKQKGLENITVDDLVSEITPRA RSLVPDEVKKEMLQRIKAFVGQQSNMNIRNARPEDLMNMQHCNLLCLPENYQMKYYFYHG LSWPQLSYVAEDDKGKIVGYVLAKMEEDPED-VPHGHITSLAVKRSHRRLGLAQKLMDQA SRSMVECFNAKYVSLHVRKSNRAALHLYKVTLKFQISETEPKYYADGEDAYAMRRDLTAF AEKYMSHTILLVQPSKKPEGRTYSDYESVNECLEGTCKIFEEYLKKMNPNSPSITYDISQ LFDFIDQLADLTCLVFDKASGKYVPHNKAWIKEKIYVLLRQQAGKMADENVDKKEEGKK- --HTYPLIQYSDMHEEMKIEAMELCVTACEKFSNNNEQAAKMIKDLMDKKFGMPWNVCVG EGFGFEVTFHKRNILFMFFGGNIGILVWKISMSHRKFSAPRHGSLGFLPKKRSRRHRGKV KAFPKDDKSKPVHLTAFLGYKAGMTHVVREVDRPGSKVHKKEVVEAVTILETPPMIVVGI VGYIETPKGLRTFKTVWAEHLGDECKRRFYKNWYRSKKKAFTKASQKWADETGKKEIDKD FNKIKKYCTVVRVLAHTQMKLMNRRQKKAHIMEIQLNGGSIPQKVDWARQHMEKAVPVKQ VFDVDEMVDVIGVTKGKGFKGVTSRWHTRKLQRKTHKGLRKVACIGAWHPSRVSFSVARA GQKGYHHRTEINKKIYRIGTGIHKEGDKLIKNNASTEHDLTEKSITPMGGFPHYGEVNQD FVMLRGCCMGPKKRVITIRKSLLIQTKRKALEKVNLKFIDTSSKFGHGRFQTHEEKKSFM GVLKKDMQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGRPINLG LWDTAGQEDYDRLRPLSYPQTDVFLICFSLISPASFENVRAKWFPEVSHHCPQTPIVLVG TKLDLREDKETIDKLKDKKLSPITYPQGLAMAKEIQAVKYLECSALTQKGLKTVFDEAIR AVLCPKPKPKQKRPCTLLVFDPNLKKKKKKKKPFDIDGLEPEIDPTDTLDKKKKKKKKQI DLSELGSALPEVVGTMKKKKKKEQSDNDYTYEELLARVFEIMREKNPDMVAGEKKKFVMK PPQVMRVGTKKTSFCNFAEICRLLHRSTKHLQAFLSAELGTSGSLDAQSQLIIKGRFQQK QIESVLRRYIKEYVTCHTCKSPETMLQKETRLFFLQCETCGSRCSVASIKSGFQAVTGKR AAIRARTTFDDAVEERIINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVARPEGK DYSLHRLILGTHTSDEQNHLLIASVQIPNDNAQFDVSHHETEKGEFGGFGSVTGKIEIDI KINHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECHPDLRLKGHQKE GYGLSWNPNTNGYLLSASDDHTICLWDINSTPREGRVVNALSIFMGHTSVVEDVSWHLLH ESIFGSVSDDQKLMIWDTRSNNTNKPSHIVDAHTAEINCLSFNPYSEFILATGSADKTVA LWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEDQSAEDA EDGPPELLFIHGGHTAKISDFSWNHNEPWVICSVSEDNIMQVWQMAENIYNDEDNDAAAA DTEMPAPSRARVYSDVNNSRPREYWDYEAHVVEWGQQSDYQIVTKIGRGKYSEVFEAMNV VTNEKCVIKILKPVKKSKIKREIKILENIRNGTNIINLLAVVKDPISRTPALIFEYINNT DFKQLYQTFSDFDVRYYTLETIKALDFCHSMGIMHRDVKPHNIMIDHENRKLRLIDWGLA EFYHPGQEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFKKEPFFHGHDNY DQLVRISKVLGTDELFEYIDKYQIVLDPRFNNILGRHSRKRLERFVNSENQHLVSQEALD FLDKLLRYDHQQRLTAQEAMKHPYFCMYVVESVPESLAKKRKLNAERESLKKKLYFERAK KYAGEYKAKENELLTYSRQARQHGNFYVPPQPKLAFVIRIRGINGLHPKPRKILQLFRLR QINNGVFIKLNKATINMLRIVEPYVTWGYPNLKSVKELIYKRGFGKVDGRRIPLTSNSII EKKLGSRNMICMEDLIHEIFTVGPNFKFASNFLWHFKLNTPNGGWRKKTNHFVDGGDFGC REDKINNLLRRMMQFLLLFSRQGKLRLQKWFTTSSDRSKKKITRELITTILARKPKMCSF IEWRDMKIVYKRYASLYFCCCVEPDDNELIVLEIIHRFVELLDKYFGSVCELDIIFNFEK AYFMLDELLLGGEIQESSKKNVLKALTAQDLLQEETPQGFFEDHGLGMSKAHPPELKKFM DKRLQLRLNGSRLITGILRGFDPFMNLVIDEAVEETKTGERNEIGMVVVRGNSVGLLEAL ERVEFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNSYQATIGIDFLSKTMYLEDRTI RLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDISNLSSFEQTTKWIDDVRMERGSDVIII LVGNKTDLFDKRQVSMEDGEKKARELDVMFIETSAKSSYNVKQLFRRVAAALPGMDTAET MQ-VELKPKETPIELHSMAIIHDMAVGLKKGHKVSAKRKRPSTRKGTQTKHAKFVRDLVR DVCGFAPYEKRSMELLKVGKDKRALKFCKRRLGTHLRGKRKREEMSTVIQKMRKAMVDEA TRKQLSSIPLLQTRAGPKDGELWVQRLKEEYQALIKYVQNNKTADNDWFRLESNKEGTRW FGKCWYIHELLKYEFDIEFDIPVLYPTIAPEIAIPELDGKTAKMYRGGKICLTEHFKPLW ARNVPKFGIGHAMALGLGPWLAVEIPDLISKGLVKHKQFLDSFGFLDDVRRMDARQLYYQ VMNFAMIVTSALMIWKGLMVLTGSESPIVVVLSGSMEPAFYRGDILFLTN-KDDPIRVGD IVVFKIEGREIPIVHRALRVHEKENGTIKFLTKGDNNQVDDRGLYAPGQLWLERKDVVGR ARGYLPYIGMITIIMNDYPKFKYFTLAMLALFALIHREMSAMNPEYDYLFKLLLIGDSGV GKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYR GAHGIIIVYDVTDQESFNNIKQWLQEIDRYASENVNKLLVGNKSDLTLKKVVDYTTAKEY ADQLHIPFLETSAKSATNVEQAFVTMAAEIKSRMGPTGPSPNVKITSSTPVKQSSGGCCQ DNLEKEILRMSNDELVSRTRLLDNEIKIMRSEVMRISHELQAQKDKIKENTEKIKVNKTL PYLVSNVIELLDVDPQDQAEEEGANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDPEQL KPGDLVGVNKDSYLILETLPAEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELIEAVVLP MTHKDRFTALGIQPPKGVLLYGPPGTGKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGA KLVRDAFSLAKEKAPAIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQSNHD IKVIAATNRVDILDPALLRSGRLDRKIEFPAPNEEARARIMQIHSRKMNVNNDVNYEELA RCTDDFNGAQCKAVCVEAGMIALRRGATELNHEDYMDAILEVQAKKKANLNYYAKDAADQ NFDYMFKLLIIGNSSVGKTSFLFRYADNSFTSAFVSTVGIDFKVKTVFRQEKRVKLQIWD TAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWSTQIKTYSWDNAQVVLVGNKC DLEDERVVSTERGKQLALNMGLEFFETSAKENISVKAVFERLVDIICDKMSESLDSETVS SKQLLEKPNNNNKGCQCFATHQLAVTRDYVSQPRLTYKTVSGVNGPLVILDGVKFPKFAE IVKLTLQDGSIRSGQVLEVSGSKAVVQVFEGTSGIDAKYTTCEFTGDILRIPVSEDMLGR VFNGSGKPVDKGPNVLAEDFLDIQGQPINPWSRIYPEEMIQTGISAIDGMNSIARGQKIP IFSANGLPHNEIAAQICRQGGLVKLPGKSVLDDHHDNFAIVFAAMGVNMETARFFKQDFE ENGSMDNVCLFLNLANDPTIERIITPRIALTTAEFMAYQCEKHVLVIMTDMSSYAEALRE VSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLT GYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGDNMTRDDHADVSNQLYACYAIG KDVQAMKAVVGEEALTPEDLLYLEFLQKFEKTFIAQSPYENRTIFETLQIGWQLLRIFPK EMLKRIPQPLLAKYYPREAGGPGFVGIKFCQECNNMLYPKEDKEQRKLLYSCRNCDFQMD ADNPCIYVNKIQHEVDELTQIIGDVIADPTLPRTEDHPCQKCEHKEAVFFQSQTRRAEEG MRLYYVCTHPSCMHRWTEKPKYKVADINLAAWGERAIEIARNEMPGLMMMQKVYGTKKPL KGARIAGCLHMTVQTAVLIETLVELGAEVQWSSCNIFSTQDHAAAAIAKRGIPCYAWKGE TDEEYLWCIEQTLFFPDGKPLNMILDDGGDLTNIVHEKHPELLPGIKGISEETTTGVHNL YKMLGKSQLKVPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGKVALVAGYGDV GKGCATALRAFGARVIISEIDPINALQAAMEGYEVTTVENALSEARIFVTTTGCKDIITG AHFPHMLDDAIVCNIGHFDIEVDVKWLNENAVSRETVKPQVDRYTLKSGRHIILLAEGRL VNLGCAMGHPSFVMSNSFTNQVLAQIELWTRTSHYPLGVHFLPKKLDEEVASLHLDHLGV KLTKLTPEQSAYLGIPIEGPYKPDHYRYADEAPEPVSNTVEEPLDLIRLSLDEKIYVKMR NERELKGRLHAYDQHLNMILGDVEETITTVVIDEETYEEIYKMTKRSIPMLFVRGDGVIL VSPPMRSMSTSNVENLNPNVIRLVTKELLDLQKNPPEGIRVTLNESDVTDIHAVIEGPEE TPYEGGSFEVKLILNRNFPQEPPKGFFLTKIFHPNVAQNGEICVNTLKKDWQPNYGIKHI LLTIKCLLIVPNPESALNEEAGKLILEQYENYCSRAKLFTEIHARPMSRTLQEIIRNNPF SSPFGLKVNQFRSLAALAEEYSCEYASNKFFALCGLGGIVSCGVTHTMIVPLDLVKCRIQ VDRAKYGNIINGFKVTLRESGVRELGKGWAPTFFGYSMQGCFKFGLYEVFKHIYADLVGE ENAFLWRTTLYLAASASAEFFADIALCPMEAVKVRIQTQPGFAVTLREGLPKFIKEEGVT GLYKGLIPLWGRQIPYTMMKFACFERTVEALYKFVVPKPRSDCTKAEQLMVTFVAGYIAG VFCAIVSHPADTIVSILNKQKGSTFIGVAKNLGFRAMWNGLFPRIIMIGTLTAAQWFIYD SVKVYFKLPRPPPPEMPESLKKKLEHWINERYAAVALLPLIPAALIYVLDTLLTAMVMHT HWRLSGVAQDYIHITIFAFGSICYFNYTDIGFANAARLLYTKLNEAEREDAAELIFPKEF ENAETLLISEVQRKTQNENAEDEQELSHVFMKTLTYTERFSKFRNRETIAAVRSLLMQNK FHKFELATLANLCPESADEAKSYIPSLEGRFEDDELQQILDDIKTKRSFQYSQQSYLAKQ DLANLKIHELNPLTPEVISRQATINIGTIGHVAHGKSTLVKALSGVQTVRFKNELERNIT IKLGYANAKIYKCDDPSVPHPQCYTSRGSAHADEITCEFSSNGKFKLVRHVSFVDCPGHD ILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMQLKHILIMQNKIDIVKESQ AKEQHEQIIRFIQGTIADGVPIIPISAQLKYNIDAVCEYIVKKIPIPIRDFTSEPRLIVI RSFDVNKPGCEVDDLKGGVAGGSILRGVLKVGQEIEVRPGIVSKDAEGKLTCKPIFSRIV SLFAEQNDLQYAVPGGLIGVGTKIDPTLCRADRLVGQMLGTVGTLPDIYIELEISYFLLR RLLGVRTEGDKKAAKVQNLSKNEIIMVNIGSLTSGGRVLAVKKDLAKVGLNNPVCTDLGE KIALSRRVEKHWRLIGWGQIRRGVSVLPMAELLLDSSIRVWVFLPIVVITFLVGIIRHYV TILLSTEKKAEMQQISDSQVMIRSRMLRENGRILPKQSFQMRKHFFNNETTGFFMKNPIT DPSMMADMMKGNFTNVLPMIIIGGWINWAFSGFLTTKVPFPLTLRFKSMLQRGVELSSLD ASWVSSASWYFLNVFGLRSMYSLILGQDNAADQTRLMQDQVSGPAIGMPPDPSKAFKAEW EALEICDHQWELENAEDELIMFLWDWFAGILNYLGLYKKSGKLVFLGLDNAGKTTLLHML KDSRMAQHVPTLHPTSEELTMGGMRFTTFDLGGHEQARRVWKDYFPAVDGIVFLVDCFDK ARLNEARKELQSLLADEQIANAPVLILGNKIDLSGACSEDEIRYMFGLHSIATGTGIRPR SELRPVELFMCSVLKRQGYGDGFRWLAQYINIVRRNRPGTKANDWCKWPDESFEEMESTL AVQQFIQQAIKRDFNNVEEILTAPEGQDEGVWKYEHLRQFCMELNGLAVKLQLECNPETC TQMTATEQWIFLCAAHKNPKECSAIDYTRHTLDGAACLLNSNKYFPSRVSIKEASVSKLG SVSRRVYRIFSHAYFHHRTLFNEYENETALCKRFTTFVIKYNLMAKDYLIVPILEEQMPQ IKLQSSDNDIFPVDIEIAKQSVMIKTMLEDDDSDEEPVPLPNVNGSILKRVIQWCTYHKD DPPTPDDDDAKDKRTDDICSWDQEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMI KGKTPEEIRKTFNIKNDFTAAEEEQVRRENEWCEEKNKRLSKGGKKGGKKKIVDPFSKKD WYDVKAPSMFNNRNIGKTIVSRTVGTKIASDGLKGRVFEVSLADLQNDEITFRKFKLMSE EVQGRHVLTNFHGMDMTTDKLRSMVKKWQTLIEAHVDVKTTDGYLLRLFCIGFTTKRQNQ LKKTSYAQSTQVRAIRKKMVEVMLREVVASDLKDVVNKLIPDSIGKDIEKYCQGIYPLHD VYVRKVKILKKPKFDLGKLLELHGEGTGK-TTEGGERIDRPGNYEPPVVDSVMSSSVVYI LDLKGKVLISRNYRGDIDSNVIDKFMPLVMEKEEEGNVTPIIQHGNVSFAYIKYNNLYLV SLTKKNANIVMVFQFLHKMVQVFLEYFKELEEESIRDNFVIIYELLDELMDFGYPQTTDS KILQEYITQEGHKLEIAPKPPMAVTNAVSWRSEGIKYRKNEVFLDVVESVNLLVSANGNV LRSEIVGAIKMRVYLSGMPELRLGLNDKVLFESTGRGKSKSVELEDVKFHQCVRLSRFDN DRTISFIPPDGEFELMSYRLNTHVKPLIWVESVIERHAHSRVEYMIKAKSQFKRRSTANN VEIIVPVPVDADSPKFKTTCGSCKYSPEQSAVIWTIKSFPGGKDYLMRAHFGLPSVTAED SEGKPPIHVHFEIPYFTVSGVQVRYLKIIEKSGYQALPWVRYITQNGDYQLRTQMGILER IAEIENEMARTQKNKATMGHLGLLKARLAKLKRELIEPKGGGGGTGEGFDVAKTGDARIG FVGFPSVGKSTLLTNLAGVYSEVAAYEFTTLTTVPGCIKYKGAKIQLLDLPGIIEGAKDG KGRGKQVIAVARTCSLVFIVLDVLKPLQHKRILESELEGFGLRLNKTPPNITFKRKDKGG INLTATVAQSELDIDTVKAILGEYRISNADVTLRHDATTEELIDVIEGNRVYVPCIYVLN KIDQISIEELDIIYKIPHCVPISAHHKWNFDDLLEKMWNYLRLVRLYTKPKGQLPDYTSP VVLKEEHQSVEDFCNKLHRNIIKEFKYALVWGSSVKHQPQKVGKEHVLNDEDVIQIVKKM AKHHPDLIFCRKQPGVAIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGSFQGRCVIC GGPGVSDAYYCKECTITEKDRDGCPKIVNLGSAKTDLFYERKKYGFKKRPTLPPINLQSL GTKNEIRKVPIPPHRRRPLQENWERIINPIVNQLKLDVRYNLKSRCVEIRNGVQTTEISA LQKAEDFVRAFSLGFEVNDAMALMRLDDLFIESFQVTDVKPLKGDHLARAIGRIAGKLGK TKFSIENATKTRIVLCDEKVHILGGYKNVDIAKTAICRLILGSPPSKIYGTMKAVAARKN EKRIQVAKPVVDLDGDEMTRIIWSWIKEKLVLPYVNVEILYYDLGLPHRDATNDQVTIDA ALAIKKHNVGIKCATITPDEERVKEFNLKKMWLSPNGTIRNILGGTVFREPIICKNIPRL VPGWIKPITIGRHAHGDQYKATDYVARGPGKLELCFTPENGEVQKLEVFTFKTTGGVGLA MYNTDESITGFANSCFQYALKKKSPLYLSTKNTILKKYDGRFKDIFQEIYEKSYQKSFES SGIWYEHRLIDDMVAQALKSAGGFVWACKNYDGDVQSDIVAQGYGSLGLMTSVLMCPDGK TMEAEAAHGTVTRHYREYQKGKPTSTNPVASIFAWTRGLEHRAVLDGNEDLKHWCTGIEK ACVDVIDSGKMTKDLAACIYGLKNVKEEHYLNTEDFLNAVKEKFDMGKLLSKIFGNKEMR ILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVKYKNVKFNIWDVGGQDKIRPLWR HYYTGTQGLIYVVDCADRDRVDEARQELHRIINDREMREAIILVFANKQDLPDAMKPHEI QEKLGLTRIRDRNWYVQPSCATTGDGLYEGLTWLTSNIKTFGDLKTSDGLKNLNTYLEDK SYITGYQPSQSDVAVFELLKGPSAEYIHCLRWFNHIKSYGDDKKKFPGEKPKLDA----- -AKKDDDDDIDLFGSEAERVKKERLAAYEAKKSEAIIAKSNIVLDVKPWDDETDMAQVEE CVRSVQCDGLLWGASKLVPLAYGIKKLQITCVVEDDKVGTDFLEEEITKFEDLVQSVDIA AFNKIKVQEVREVTRIERIGAHSHIRGLGLDDALEARKISQGMVGQVSARRAAGIILEMI KEGKIAGRAILIAGHPGTGKTAIAMGIAQALGSDTPFTSIAGSEIFSLEMSKTEALTQAF RKSIGVRIKEETEIIEGEVIEIQVDRPATGTGSKVGKLTIKTTEMETIYDLGQKMIESLT KEKVQAGDIITIDKATGKITKLGRSFTRARDYDAMAANTRFVQCPEGELQKRKEVVHTVS LHEIDVINSRTQGFLALFSGDTGEIKSEIREQINFKVAEWREEGKAEIVPGVLFIDEVHM LDIECFSFLNRAVESDMAPILIVATNRGITKIRGTNYKSPHGVPIDLLDRLLIISTTPYE NDEINQILKIRCEEEDVEMTEDALTVLTRIGQETSLRYAIQLITTAYLVCRKRKGKEVGI EDVKRVYSLFLDESRSTQYLKEYQQEYMFYEMAEYDLTNHMAPYLDRHMVLPLMEFLSGK EIYDINTLLRVKIDLLESTKMVDYSTDVYKLLHPNAEPPQAMVDKRQDVLSQMKELEAET EPLINILGNDETNIQNTRDSRQLLEYLSKK-GFKMEMLDTLYKCAKFHFECGNYTRSSQY LYFVRVLLPPSDRNFMNTMWGKLASDILMQDWENAIDDVSKLKEVLDSPLVLLQQRTWLI HWSLFVFFNHSKGRDLIIDMFLYSPHYLNAIQTMCPHILRYVTSAVITNRQLLKDLVKVI QQESYSYKDPITEFISCLYVNFDFDGAQKKLVECKTVISNDFFLVGCLDDFIENARLLIF ETFCKIHNRISISLLAEKLNMEEEEAERWIVNLIRNARLDAKIDSKLGLVVMGPQATSAY QQVIEKTKNLAFKTQMLVMNIEKKFSVKEMGVDVQTITAGDGKTFPQKGQTVIVHYTGTL VDGKKFDSSRDRGRPFEFQIGVGQVIRGWDEGVAKMSVGQVAKLTCTPDYAYGSSGAGGV IPPNSTLIFDVELIGVKMPKYYCDYCDTYLTHDSPSVRKTHCGGRKHKENVCTYYQKWLE EQVQKLVDDTTAAFKAGKIPSNPYLNLGAMIPPPMAL-LGPPGA-PPMFMPPPMGSLPPL RPP--------PMGLPPEPLSLARDVQRAVEILDILQKSGDFDKLASLQKILQSEFCVAV REVYEHVYETVDLSGSTDVRANATAKATVAAFAASEGHAHPRIVELPKTEEGLGFNVMGG REQNSPIYISRIIPGGVADRHGSLKRGDQLLSVNGVSVEGEPHEKAVELLKAAQGSVKLV VRYTPKVLEEMEARFDRQRMARRRQIVKLIATVFTEPTVYFKEEFWRSRWVESTAKGSDQ GEFGWSAGKFFNDPEKDKGLKTTQDAKFYGISAKFDKPFSNEGKTLVVQFSVKHEQEIDC GGGYVKIFPSDLDQKNMHGDSPYNIMFGPDICGYSTKKVHVIFNYNGKNLLTKKEIRCKD DVLTHLYTLIVRPDNTYEVKIDNKKEESGTLEEDWDFLEPKKIKDPDAKKPEDWDDRENI DDPDDKKPEDWDKPEHIPDATATKPEDWDDEMDGEWEPPMVDNPEYKGEWKPKQIPNPSY KGSWVHPEIDNPAYVADSKLYSYSDIGAIGFDLWQVKSGSIFDNILITDDEAYAEKYGEE TWGVMKAGEAKAKEKADEIENKKHKAKADDDDDDEDENDEKKTDMEPGLLDPSMYLVKGI LIMDNDGNRLFARYYDSLFPTVKEQKSLFSKTHKTNAEILMLEGLICIYRSSVDLLFYVI GSAQENELILVSVLNCIHESISTLLRKNVEKRALLDNMDGVFLAIDEICDSGLILECDPA IVSQRACFRMDDLPLGEQTIASVIQSAKDQIKWPLLKMNIFRLVGDLSHLAALIILLLKI WKSRSCAGVSGKSQIMFAMVYMTRYLDLFTTFVSVYNSVMKVVFLLFSFVTVYLIYFKFK ATYDGNHDTFRVEFLVVPVAGLAVLVNHEFSFLEILWTFSIYLESVAILPQLFMISKTGE AETITSHYLFALGIYRALYIANWIFRYYMEGFFDFIAIVAGCVQTILYCDFFYLYVTKVW KGKRLTIPAMKIEEVKHTTKSQRIAAHSHVKGLGLDENGFALQMASGLVGQEQAREAAGI VLEMIRSKKMSGRAVLLAGPPGTGKTAIALALAQELGSKVPFCPMVGSEVYSTEIKKTEV LMENFRRAIGLRIKETKEVYEGEVTELTPAEIENSFGGYGKTISHVIIGLKTAKGSKQLK LDPTIYDGLQKEKVEVGDVIYIEANSGAVKRQGRSDIYATEFDLEAEEYVPLPKGDVHKK KEVVQDVTLHDLDVANAKPQGGQDVISMLGQFMKPKKTEITDKLRQEINKIVNKYIDQGI AELVPGVLFIDEVHMLDIECFTYLHRALESTIAPIVIFATNRGKCSIRGTEDLVAPHGIP LDLLDRLMIVRTMPYSKEEIQQIISLRAQTENIQIEEEALAKMSEIGVKTTLRYVTQLLT PASILAKTNGKEKISKEEVDETHSLFFDAKSSAKILAEQKDKYMKEFEVDDEADKGIQKL KEGAKRRKGRGFLTRGNVDEYESMEVKENGPQRSVEGWIVFVTNIHEETQEDDVREKFEE FGEIKNLHLNLDRRTGFLKGYALVEYNTYKEAEAAIQTLNGTDICGQKINVDWTFVKGPN KKRMSYQLYRNTTLGHTLQESLDELIQVGQITPQLALKVLLQFDKSINQALSNRVNKKIT FKADLNTYRFCDNVWTFVLNNAEFRRVDKVKIVACDGKSTFLFTSESVGEGHPDKICDQV SDAVLDAHLSQDPNAKVACETAAKTGMIMLLGEITSKANVDYQKVVRDTIKYIGYDDSSK GFDYKTCNVLSALEQQSPDIAQGVHIGRDEENIGAGDQGLMFGYATDETEECMPLTIILA HKLNQKISELRRSGVLAWARPDTKTQVTCEYRMLKGACIPQRVHSIVISVQHSEDVTLEQ IQKDLKEKVIKAVVASKYLDERTVYHLNPSGKFVIGGPQGDAGLTGRKIIVDTYGGWGAH GGGAFSGKDFSKVDRSAAYAARWVAKSLVKAGLCKRVLVQVSYAIGVAKPLAVFVSSYGT GVKPDSELLRIVMENFDLRPGRIVKDLDLKRPIYFKTASYGHFGRPEFTWEQPKPLKFMA GSALKRLMAEYRQLTLNPPEGILAGPSNEDNFFEWEALIAGPEGTCFEGGVFPARLTFPS DYPLSPPKMKFTCNIFHPNIYKDGQVCISILHAPGDDPMGYESSSERWSPVQSVEKILLS VVSMLAEPNDESAANVDAAKVWREDRNKFDEMARKTVEKSLGIMRIERCYFCSSPCYPGH GTTFVRNDNKVFRFCRGKCHKAFNKKRNPRKVRWTKAFRKCSGKELTVDPVYELEKRRNI PIKYERELMKKTIAGMKRIHELRVKREAQYIKERLTKGKELRKKDDIREVTKCIHLIKSP AVAMATYKVVMVRHGESAWNAENRFCGWFDADLADCGVVEAKRAAQRLKEKGFTFDVAFT SVLKRAIKTLFYIQDGLDLHWIPVHKHWRLNERMYGALQGLNKSETAAKHGEDQVKIWRR SYDVPPPPVDKTSPYWPGKDCKYKYVDTNLIPRTECLKDTVARALPYWHDIIVPEIKKGQ KVIIAAHGNSLRALVKYLDNMTDEQIMALNIPTGIPLVYELNADLQPITHYYLASDEEVK AAIDKVANQGKAKMELQDIFYDKSEYIETASGNKVSRQSILCGSQNIVLNGKTIIMNNCI IRGDLANVRIGKHCIVGLRTVVRPPFKKFSKGVAFFPLQIGDNVIIEEDSVINAAHIGSF VHIGKNCVIGRRCVLKDCCAIADNTVLPPETVVPPFTLYSGNPGMSFFFGQRNYKTFKPK KHIPEGSHQHDLMKHAAATLGSGNLRLAVALPEGEDLNEWVAVNTVDFFNQINMLYGTIT EYCREDSCPVMSAGKKYEYHWADGLTIKKPIKCSAPKYIDYMMTWVQDQLDDESIFPSKI GVPFPKNFLSISKTILKRLFRVYAHVYHQHFEQVVNLQEEAHLNTSFKHFIYFVQEFSLV DKKELMPLQDLIDRLTAKDMGIDICHKHDRKVHRKEPKTDDIYLRLLVKLYKFLARRTNA KFNQIVFKRLIMSRTNKPPLSLSRLSRHMKKQGRENKLAVVVGTVTDDERLYTVPKLKLV ALRVTDTARTRILKAGGEILTFDQLALKAPKGENTVLLQGQRKARKAYRHFGLAPGVPHS HTKPYVRAKGRKFERARGRRKSRGYKNDLKFFNVIGSYNLAQTCALLKELISEEPWSTTD DIKSNLKEISVQIAEAFPKETCFTHVFNRFFKLFHDEITLEIVQEMTDDIEASRHALEII RPLEMIKTVEMFLKADFHVMVLEKQGREMAAALASHDIPTTLIKDGSMHAIMSTVTKVIV GAHTITSNGGIKGLMSLSLAQVASFENKPFIVVAPSFKLSEKHFLCFDIQSNIFLSPYEI NNHVFDFVPPEFITLIMTNLGPSIPSQLYRLVNEVYNMIIPIRCFTCGKVIGNKWDQYLA LLQAEYTEGDALDALGLKRYCCRRMLLTHVDLIEKLLNYAPLEKRTPEPVEGRQHMEMQT ELYLEEFGDMIEEVNQGCQTDPFINKPPTPMFVPAKIGIDASTQIFDGDLFDFDVEVRPM VEVLIGKVLEQSLMEVMEEEELASLRERQRMFEEMRNAELQEQQRLEEEDRRRKDEKLKR MKHQQELIRKEKETAEKIAAKAFAQSFLSDLVPSVVASLSENGYFHDPIEAELEKNFMED LMRGVCKRLRYEVISRKLIDRIIKKIVRQREEQYLKMKAKGDLKEYKVVGRMMPTDKMRT PPIYQMRIFAPDRPQAKSRFWFYASYLRKVKRTQGEILLCQQIYEKRPTSIKNFGVWLRY DSRSGTHNMYREYRDLTTAGAITQCYRDMGARHRARASSIQIIKVNPIPSSKVRSKNLNQ FIDSRIKFPLTHRVNRRLHHPRFTTTRPHTTFSAFNEMQRFWDKNLGRPNSPWVIYRPHL PMITSFCHRVTGIAMGVVFYAFSIGVFLAPGDFPSYVEFVKNLQLPQLFLFPAKTIVAFP LVYHYINGIRHLTWDAGHGFELKTQYKSGAIILASIAYWDDAVELSSYRDQHFKGNRHEQ EEKLLISSTLYIGNLSFYTCEEQIHELFSQAGDVKRIIMGLDKFKKTPCGFCFVEYYIRE DAENAMRFINGMRLDDRVIRTDWDAGFIEGRQFGRGKSGGQVRDEYRNDYDDGRGGYGKL VQQRIKSNYTLKYTLAGHTKAVSSVKFSPNGEWLASSAADKLIKIWGAYDGKFEKTISGH KLGISDLAWSSDSKLIVSGSDDKTLRVWDVASGKCLKTLKGHSNYVFCCNFNPQSNLIVS GSFDESVRTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID DDNPPVSFVKFSPNGKYILAATLDNSLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG KWIVSGSEDNLVYIWNLQTKEVVQKLVGHSDVVLCCACHPTENIIASAALENDKTIKLWR SDIMIIYKDAFTGDELFSDSVPNIVYKLKGTDDSAIGGNKSQGVDIVLNAKKDYLPHIKA YMKQVKEYQLFSGLALMKWDVPYMYFFKHGLIEEKVMAVEFDGGVVIGADTRTTTGSYVY NRITDKLTKVSETIYCCKSGSSADTQAISDVVSYHLSVHKLEFGGEPLVKTAAKIFQDLC YNYRDQMSAGIICAGWDHIHGGQVYCIPLGGMCIRQPVTIGGSGSTYIYGYVDATYKEKM SVKECQEFVANAITLAIGRDGSSGGFVRLATITKDGVERMTVLPNQLPKFVCIGILALLI LLCCCGCLLRMCWKRRKGKEGKKGLKGAVDLKNVQLLGSSMKEKVQPDLESLEGNMEDNE GVENAKEEVKLGKLQFSMDYDFQKSELSVGVIQAVDLPGMDMSGTSDPYVKVYIMPDKKK KFETKVHRKTLNPVFNETFVFKVPYAEIGSKTLTFAVYDFDRFSKHDQIGQVLVPLNSVD LGRVVEEWRDLTSPESE-EKENKLGDICFSLRYVPTAGKLTIVILEAKNLKKMDVGGLSD PYVKLALLMNGKRIKKKKSTIKKCTLNPYWNESFSFEVAFEQIQKISLDITVVDYDRIGT SDPIGHVLLGCNATGTELRHWSDMLANPRRPIAQWHTLQEVPEKNMVLADLGRKITSALR AFSSATVINEEVLNSMLKEICAALLASDVNVVLVKKLRENVRSVIDFDEMAAGLNKRRMI QSAVFKELVKLIDPGVKAWQPQKNHANVVMFVGLQGSGKTTTCTKMAYYYQKKNWKTCLV CADTFRAGAFDQVKQNATKAKIPFYGMDPRVLHSMGQNMMKKLQQGAGANPDNIVFVMDA SIGQACEAQARAFKDKVDVASVIVTKLDSHAKGGGALSAVTKSPIIFIGTGEHIDDFEAF KVQPFVSKLLGMGDIEGLIDKVSELKLDDEELMKKLKQ---------------GQFTLRD MYEQFQNIMMSIMSYNGAAIIAMRGKDCVAIAADRRFGIQAQTVSMDFEKVFKLGQHLYI GLGGLATDVQTVIERLRFRVNLYELKENRRITPKALLSLVSNFLYEHRFGPYFIEPVIAG LDPKTGQPFTASTDLIGCSSEAEDFSISGTCTEQMYGMCESLWKPDMSPDELTEVISQAL LNAQDRDAVSGWGAIVRIIEKDKVTTKILKARMDMTSKDYYFDSYAHFGIHEEMMKDEVR TLTYRNAMYHNRHLFKDKVVLDVGSGTGILCMFAAKAGAKMVIGIECSSIIEQSEKIIQA NKLDHVIKLVRGKVEEVILPNGIEKVDIIISEWMGYCLFYESMLKTVIYARDKWLAQGGL IFPDRASLYICAIEDRQYKDEKINWWDNVYGFDMSCIKKVAISEPLVDVVDPKQVVTNNC LLKEVDMYRVTEEDLSFSSQFCLMCRRSDYVQAFVTYFNIDFTCCHKPTGFSTAPGARYT HWKQTDDYLTVKSNEEIVGVFHIKPNTRNNRDLDFVLDVSFHGDLSSLDTSMTYKMRMVK EDRSTWKAGYFTKLISLLDEYPRCFIVGADNVGSSQMQKIRIALRVLMGKNTMMRKAIRG HIENNPALEKLLPHIKGNIGLVFTKGELTDVRKIIEENKVAAPAKAGAFAPLDVTVPAQN TSLGPEKTSFFQALAIQTKISKGTIEILNDVKLIKAGDKVGASEATLLNMLNISPFTYGL LIEQVYDSGTVFDVSILDITDDDIRSKFMEGVANLASLSLEIGYPTMVSVPHSIINAFKN LLSVALCTDITFEEAEAIKESITRGKLIAVIGDEDTCTGFLLGGIGELDKHRHPNFLVVE KTTSVSEIEECFKKFTSRDDIAIVLINQNIAELIRNVIDVYNQTIPTILEIPSKEHPYDP EKDSILRRAKGMFSGEEMRGNEASLPMELCSTFDVEEIKRLGKRFRKLDLDGSGSLSIDE FMSLPELKQNPLVQRVIEIFDTDGNGEVDFKEFIEGVSLFSVKGDKLSKLKFAFKIYDID RDGFISNGELFQVLKMMVGNNLKDSQLQQIVDKTIINADKDGDGKISFDEFCAVVGNMDV HKKMVVDVMTYLRSWEEFSKAAERLYTDDPMKCRYVIKYNHVKGMVVLKMTNDKVCIQYR SEHAQDVKKIEKFTSQLMRHMASKEVFQEVKLYKTARERDRYDSLAELFALVNTLQCLEK AYIKDSVTPSEYTAACSKLLVQIKAAFKQVQDDEHPTIEEFTRKRKMNCAAALERIKEDR PITIKDDKGNTSRCIADIVSLFITIMDKLRLEIKCMDELQPDLKELYDTMNRLSLLDSNY IGKSKVSEWLSVLSVMQASDQLSEPQVRQLLFDLDSSYQAFNHVLHNMLSSMVKEHQAKQ AQNRELQEKRRLEATVTTKFANALVDSLNKGVGQAYVNQKKLDTETKILHANVMQLTKQT NLWLKLINDFNQAVKEIGDVENWSRSIEADMRTISSALEYVYKAHVVEKQVNGDKNGGKR LVVVRRQPRYLNTQDKPWRMRSPFSQHKRYLRSSITPGTVLIMVAGRHKGKRVVFLKQLK SGLLLVTGPYHLNGCPLRRINQIYVIATKTKLDISAVKIPERLTDDYFKRKTLKRPKHTE GEIFDTKKEKYAVTEERKKDQVDVDGQILQVVRNHPDKKFLFGYLGSLFSLKNGEYPHKL IFMSWIFGRKKTPQEMLRQSQRALNKAMRDIDRERQSMENQEKKIIIDIKKMAKQGQMDA VKILARDLVRTRRYVKKFILMRANIQAVSLKIQTLKSNDAMASAMKGVTKAMATMNKQMK LPQIQQIMQEFEKQSEIMDMKEEMMNDVIDDALGEDDDEEESEAIVTQVLDELGLQMADQ LSDLSAPSSK-KQQPSGVSDADADLEARLENLRRQSKYCDFCLGDEMENRKTGLKEEMVS CADCGRSGHPSCLQFSPNMIISVKQYPWQCIECKSCGICGTSDNDDQLLFCDDCDRGYHM YCLKPPLSEPPEGSWSCHLCVVEFYGTLERTISLYPLTNYTFGTKDPQYEKDQSIVARFD RMKEDFKKTGMRRSVEGVLIVHEHGLPHVLLLQLGTSYFKLPGGELKPGEDQVGGLKRLL TEMLGRQDQPPVEWTIEDTIANWWRPNFESPQYPYIPAHITKPKEHKRLYLVQLPEKALF AVPRNYKLVAAPLFELYDNSAGYGPIISCLPQNLSRFNFIYNFTPSATTPVGPKAMSMAT PTPGHVVPMTPEQMQAWTLQKELDERNRPLTEEEIDAVLPEGFKILQPPAGYVPIRTPAR KLTATPTPIAGTPTGFRMQTHVVDLQPKGNLPMMKPDDMQYFDRKIMKLLLKIKNGTPPM RKAALRQMTEKARELGANSLFNQILPLLMSPTLEDQERHLLVKVIDRILYKLDDLVRPFV HKILVVIEPLLIDEDYFARVEGREIISNLAKAAGLATMISTMRPDIDNMDEYVRNTTARA FAVVASALGIPSLLPFLKAVCKSKKSWQARHTGIKIVQQISILLGCAILPHLKSLVEIIE HGLVDEQQKVRTITALALAALAEAATPYGIESFDSVLKPLWKGIRQHRGKGLAAFLKAIG YLIPLMDAEYANYYTKEVMLILIREFQSPDEEMKKIVLKVVKQCCATDGVEPMYIKDEVL PPFFKCFWNQRMALDRRNYRQLVDTTVEIATKVGASEIVGRVVDDLKDEAEQYRKMVMET IEKVMANLGATDVDSRLEEQLIDGILYAFQEQTAEDIVMLNGFGTVVNALGKRVKPYLPQ ICGTILWRLNNKAAKVRQQAADLISRIANVMKLCQEEKLMGHLGVVLYEYLGEEYPEVLG SILGALKAIVNVIGMTKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGAEFVS AREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVC TTVAIAIVAETCSPFTVLPGLMNEYRVPELNVQNGVLKSLSFMFEYIGEMGKDYVYSVTP LLEDALMDRDLVHRQTAMAAIGHLALGVYGFGCEDALTHLLNYVWPNVFETSPHVIQAFM SAVEGMRLALGPTKILHYVSQGLFHPARKVRDVYWKVYNSLYIGSQDALVPAYPRIFNDD KNQYIRYELDYLLDDYMVGDEEYDLEYSEDSNSEPDVDLENQYYNSKALKEDDPKAALEN FQKVLDLEGKDKGDWGFKALKQMIKINFRLGQHREMMSRYKQLLTYIKSAVTRNYSEKSI NSILDYISTSKQADLLQNFYQTTLDALKEAKNERLWFKTNTKLGKLYFDREDWTKLQKII RQLHGSCQTEEGEDDMKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPL IMGVIRECGGKMHLREGEYGKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGIN PFDSQEAKPYKNNPEILAMTNLVSAYQNNDICDFEKILKTNRENIMEDPFIREHIEDLLR NIRTQVLIKLIKPYTRIHIPFISQELNIDVNEVECLLVSCILDNTIRGRIDQVNQLLELE TGVARYNAVHKWANQLSSLHEAIVSRMAVLLMGKSGAGKTSMRSIIFANFIAKDTRRLGA TIDVEHAHVRFLGNLILNLWDCGGQEAFMESFISNQRDNIFKSVEVLIYVFDVESRELEK DLENYKACLDALRQNSPEAKIFCLVHKMDLIPLDQQQALFDERKNILIQNSAPMATSIWD ETLYKAWSTIVYQLIPNINQIESSLVKFAEVLEADEILLIEKATFLVICHCERKAHPDAQ RFEKISNIIKQFKISCSKVTAVFNSIEVRNSKFAAYIESFTPNTYVMVVTSDPELTSVMT LMNIHNGRKHFEKLEKVEAILSFSVRLFSVLRYESVIHEFDPYFNYRTTRFLAEEGFYNF HNWFDDRAWYPLGRIIGGTIYPGLMLTSALLHNILNFLHITIHIRDVCVFLAPLFSSLTV IVTYHLTKELKDVGAGLVAASMIAIVPGYISRSVAGSYDNEGIAIFCMLLTYLFWIKSVK TGSLCWSVMCAVAYFYMVSSWGGYVFLINLIPLHVLALMATGRFSHRIYVAYSTVYCVGT ILSMQIPFVGFQPVQSSEHMAALGVFGLCQIHAFIDYVRSRLTRDQFSILFRSLVIFTGV VIATALGKISPWTGRFYSLLDPSYAKNNIPIIASVSEHQPTSWSSFYFDLQILVILFPAG LYFCFKKLTDANIFIILYGITSIYFAGVMVRLMLVLAPVMCILSGIAVSSTLSEYMKNLD SAKKPDANYPVKNEVATGVVAMVTIFLVMYTFHCSWVTSEAYSSPSIVLAARGGDGGRII FDDFREAYYWLRYNTPEDAKVMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMSS TEEKAYEIMRELDVSYVLVIFGGLTGYSSDDINKFLWMVRIGGSTDRGAHIKETDYYTPQ GEFRVDKEGSPTLLNCLMYKMCYYRFGSVYTESGKPTGYDRVRNVEIGNKDFELDVLEEA YTTEHWLVRIYKVKDLSNRGNKLNIKPLLKIVLGRFFGNFTGFVSMCVQHIKSPIDNARR KIEHIYTGPLDTELANHMFNCDPDGPLMVHTTKLYPTYDATTFHALGRIMSGTLSSDQNV RILGENYSLEDEEDSRMGLVNRLWISEARYNIEVNRVPAGNWVLIEGIDQPIVKTSTITD VSGNEGAHIFRPFKFNTSSVIKIAVEPVNPSELPKMLDGLRKVNKSYPLVTTKVEESGEH VILGTGELYLDCIMHDLRKMYSEIDIKVADPVVSFCETVVETSSLKCFAETPNKKNKITM IAEPLEKGLAEDIENEVVQIGWPRKRLGEFFQNKYDWDLLASRSIWAFGPDTTGPNILVD DTLPSEVDKTLLASVKDSIVQGFQWGTREGPLCDEPIRNVRFKILDAQISTEPIQRAGGQ VIPTARRVAYSAFLMATPRLMEPYFFVEVQAPADCVSAVYTVLARRRGHVTQDAPVPGSP LYTIKAFMPAIDSFGFETDLRTHTQGQAFCLSVFHHWQIVPGDPLDKSIVIRPLEPQPAT YLAREFMVKTRRRKGLSEDVSINKFFDDPMLLELAKQDVVLSYAMMETFSLFDNKGDGKI AVNQLGEVLRAMGQNPTEAEVKKCKEPESRISFETFLPILVTISKNKEAPKVEDFIEGFR VFDKDQNGTIHSAELRHLLTNLGERLTDDEVNELLQGHEDAQGNVNYEEFIKKVITGMNS LNFNLNFGYLEGLLRGFKAGILKQSDYLNLIQCETLEDLKLHLQSTDYGNFLANEASPIQ VGTIDDKLKEKLVVEFQHIRNHSLPPLSNFLDYITYSYMIDNIVLLITGTLHQRSISELI PKCHPLGSFEQMEAIHIASNAAELYNAVLVDTPLAPYFIDCISEQDLDEMNIEIIRNTLY KAYLEDFYKFCQTLGDSTAEMMSTALEFEADRRAFIITINSFGTELSKDERAKLYPRMGK LYPDGLAALARAEDYDQVKSVAEFYAEYKQIFDE---TQGDKTLEDKFFEHEVKLMKNAF MNQFHFGIFYAFVKLKEQENRNIVWIAECVSQRHRTKIDSYIPIFSPRKAMRKISRIPFK VLDAPELQDDFYLNLVDWSLQNTLSVGLGSCVYLWSACTSQVTRLCDLSSEADSVTSVSW SEKSSMLAVGTHRGLTQIWDVSVNKKVSTLVGHTARVGALAWNADLLASGSRDRLVLLRD TRTPSSNVDRKLPSHKQEVCGLKWSPDYQHLASGGNDNKLYIWNTRSSEPVLAYSDHIAA VKAIAWSPHQHGLLASGGGTADRRIRFWNTITGRPLQCVDTGSQVCNLAWSKHSSELVST HGYSQNQILVWKYPSLAQIAKLTGHTLRVLYLAMSPDGESIVTGAGDETLRFWNVFNKTR STKESNSALNLFTRIRAFIICSFYFTFTNQGYRYGISWILDQTSPFMWANLGIGLSISLS VVGAAWGILTTGSSILGGGVKAPRIRTKNLVSIIFCEAVAIYGIILAIVISNYNNHFAGY SMFGAGLTVGFSNLFCGICVGIVGSGAALADAQNATLFVKILVVEIFGSAIGLFGVIVAI LQIQKVKMGDKMAASRRLTKELQDHVDESNILVWSGLVVPENVPYNKGAFRVRIDFPAEY PFKPPKITFQTKIYHPNIDEKGQVCLPIISSENWKPATRTDQVIQALTALVNEPEPEHPL RADLAEEYTKDKKKFLKNAEEHTKKYAERRPSDGASDTFPMQCSALRKNGFVVLKGKPCK IVDMTTSKTGKHGHAKVHLVGLDIFTGKKCEDICPSTHNMQVPSVTRKELEVIDLSEGFF SLMGEDGDMRDDLKITATVWKAMGEEVVKELKTGKGKLVGPKGVAIDAQGRVVVVDNKSS TVFLYTLSGKILGKFGLRAQARMAGPHFCAIDPDGDVVVTDFHNHKVKVFTEGQYKFTFG SAGDGNGQFSAPTGVCIDSQGNILVADWGNSRVQIFDKNGSFLCFIDLYGPQGIAMTKDN DIIVADSGNHCLKIYKQLMAAGPIAERNQDATIYVGGLDEKVTDSILWEMFLQSGPVVNV HMPKDRITQSHQGYGFVEFMGEDDADYAIKIMNMIKLFGKPIRVNKASAHQKNLDVGANL FIGNLDPEVDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGFAFINYASFDAADAAMEAM NGQYLCNRAITISYAFKKDSKGERHGSAAERLLAAQNPLSHADRPHQLFADAPPMM--IP MIPPPPPPGVMPMPMPPPAMQGMFMQPPRQPPPPEHPPPSMMG--------GMPNFQGGP PPMPPPGGQPMSHSMLPPPPKVEVKKTVNPLFEKRAKNFGIGQDIQPKRDLSRFVRWPKY IRLQRQKRILYQRLKVPPPIHQFNQALDRQNVTQLFRLMDKYKPETKVEKKIRLVEMAKN KVKGKSVEQTKRPPVMRSGINTVTALVERKKTDLVVIASDVDPIEIVLFLPALCRKMGVA YCIVLGRVVHRKTVTCLAFPTVNSEDRSALNKLVETVKTDFNERAEEIRRHWGGGVMGHK SQARIAKLEKAKAKELAQRMRYVSAYLLARLGGNENPKEVDIKKILSSVGIDSDDALVKK VVSELSGKNIEELIAAGREKLASVPSGGAVVAAKAKEEEEDDGDMGFGLFDMVIQKLHAR QIFDSRGNPTVEVDLTTDKGTFRAAVPSGASTGIHEALELRDKVAADYHGKGVLKAVGNI NNIIAPALVIDVTNQSCVDEFLLKLDGTENKSKLGANAILGVSLAVCQAGAKQKGVPLYR HIADLAGNKELVLPVPAFNVINGGSHAGNKLAMQEFMLLPTGASSFTQAMKMGSEVYHHL KSVIKAKYGQDACNVGDEGGFAPNIQNNEEGLELLKTAIEKAGYTGKIEIGMDVAASEFY KKYDLDFKNPKSDPAQWLTSDQLFEVYKGFLAKYPVVSIEDAFDQDDWAAWTKMNSIQLV GDDLTVTNPKRVNIAIEKKACNCLLLKVNQIGSVSESIQACKLAQSAGWGVMVSHRSGET EDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELHGSAKYAGKHFRNPGNPPL ARSTKVRCCISTDFRKFYHRGDLPVRV---INSRKILWTVPIESLDYDFYLPLFFDGLVE LEHPFELLAYLGAYEMIENTGCKVNPVLSRLILPMKNALCTRNCRVIMKVLKLIQVMIVK ESEIGISLVPYYRHLLGILNIFKNKNVTTGDLIEFGH--RDNLGDLINETLEMMERCGGD NAFINIKYMIPTYESCFMNAPPTFESFLLFDGDKKVTIEKDTKVPNASIFTILKEDHTLG NLLKNQLLKDPHVLFAGYKIPHPLEHKFVLRIQTTSEYSPQEAFTNAITDLISEISLLEE RFSEAIRERQERDEDHRRKWDLDEYDRLARERTEEEDRRKEAPVRRELLKPRDYKVDLDS RLGKSHVITKTTPASQMGGYYCNVCDCIVKDSINFLDHINGKKHQRNLGMSMKVERSSLD QVRKRFETNKRKKEEEEKHYVFEEKIKELKEEEEKQKAYKKEKRKGKKRKSFDDERDGEV TSIMGFSGFGTSKKMGCSMSAEDRLAVERNKQIEKSLREDGQQAAKDIKLLLLGAGESGK STIVKQMKIIHEGGFTSEDNKQFKPVVYSNTIQSLVAIIRAMSILHIEFGDPERETDAKL ILDVIQRMEDTEPFTDELLAAMKRLWADSGVQECFNRSNEYQLNDSAKYFLDDIDRLGSK DYMPTEQDILRTRVKTTGIVEVHFNFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCV GMSEYDQVLHEDETTNRMQESLKLFDSICNNKWFTDTT-----KPHKMITNPNFAGSNTF EEASSYIQAQFEAKNKSTTKEIYCHQTCATDTNNIQFVFDAVTDVIIANNLRGCGLYYHS QFVNAPQVVGNMALLPLKTQFKGPALDIIEEALSFFKANVFFRNYEIKSEADRTLIYLTL YISECLKKLQKCKSKNEGLKEMQSLAISRFYLPGEAQFPLNAMYAKPANKNEEDNMRAYI QQLRQEMGLRLCDRVFD-ETDKPSKWWMCFVKRRFMDKSLSGPGQAGPYNYSYIFKYIII GDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVAGQKIKLQIWDTAGQERFRAVT RSYYRGAAGALMVYDITRRSTYNHLNSWLSDARNLTNPNTVIFMVGNKSDLEAQRDVTYE EAKQFADENGLLFMESSAKTGDNVEDAFLDTAKKIYQNIQDGSLDLNAAESGVQHKPMAA RGSLANDQTASRDGCSCMKFAAVSVMRDGPVKGVVHFSQDANTKIFGEITGLTPGKHGFH VHEFGDNTNGCMSAGGHYNPFLKSHGGPGDSLRHVGDLGNVVADKFEMVDSLIQLTGAES VIGRTLVIHADEDDLGKGGYEDSTTTGHAGARVACGVIGIAKMVNFTIDEIREIMDKKKN IRNMSVIAHVDHGKSTLTDSLVSKAGIIAGAKAGEMRFTDTRKDEQERCITIKSTAISLY YSLPEKDLINSFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQA IAERIKPVLFMNKMDLALLTLQLAPEELYQTFQRTVENVNVIIATYGEDGGPMGEVMVDP AKGTVGFGSGLHGWAFTLKQFAEIYSEKFKIEAHKLMKRLWGDQFYNYVRGFTQYILDPI YKVFEFCMPKEDALALCEKLGIKLTTEEKENQEKQLMKVVMRKWLPAGDALLQMITIHLP SPVTAQKYRMELLYEGPHDDEAAIAIKNCDPKGPLMMYVSKMVPTSDKGRFFAFGRVFSG VVVTGMKARIMGPNFVPVKNIQRTILMMGRYTEPIEDVPCGNVCGLVGVDQFLVKTGTIT TFENAHNLRVMKFSVSPVVRVAVECKNPADLPKLVEGLKRLSKSDPLVQISIEESGEHII AGAGELHLEICLKDLEEDHACVPIKVSEPVVSYRETVSEESDRMCLSKSPNKHNRLYMKA VPMPDGLSDDIDKGEVHPRQEVKERARYLAEKYDYDVTEARKIWCFGPETNGPNLVMDCT KGVQYLNEIKDSVVAGFQWASKEGVLCEENMRGVRFNIYDVTLHADAIHRGGGQIIPTAR RCFYASVLTAAPRLLEPVYLVEIQSPEAAVGGIYGVLNRRRGHVFEENRVIGTPMFVVKA YLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILVVTETRKRKGLKEGVPPLDNFFDKLM LPISLLKTAVNHPMLVELKNGETYNGHLVCCDAWMNINLREVICTSRDGDRFWKMPECYI RGSMIKYLRIPDEVIDMVKEEIHQKNRGRGEMRTRGRGGPGRGVFSNRGGRQNRGGRGGG AGASEIKLSNPPSDCISSLCFSPTSSQFLLVSSWDNNVRLYDVNENVLRTQYSHTHAVLD CCFQ----------------------AKSVIGTHAAPIKCVEFSSEHNVIITGSWDSNVK LWDPRSPTTVTSLLQSNKVYTMSLCGDKLIVGAAKRKVLIWDLRNTGYVEQKRESSLRYQ TRCIKAFPNKQGYVLSCIEGRVAVEYIDHSPEIQKKKYAFKCHRIKED-VEKIYPVNALA FHNIHSTFASGGSDGFVNIWDGFNKKRLCQFHRYPTSISALCFDNSGTVLAIASSYLYED DYPEDNVFIRRVTDHETKPKMDFQHRPGGKTGMGGVASASDANRDRRERLRLLALETIDL NKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQANLAQRAAKEAKESPIQPSLE KPRIDVRKFVKIGRPGYKVTKQREPETGQQSLLFQIDYPEIVDNIQPKHRFMAAYEQRIE PPDKRWQYLLFAAEPYETIGFKVPSREVDKESSKFWTSWNKETKQFFLQFAFKLESTSLP PPPPPMRPPPGLMDEEAEIRKLWRIRKTIMQLCHDRMYLVTQSELDQNLEQFKQQFC-RP GERCPPRSELMVLVAHNDDPTDQLFVFFPDEPKVGIKTIKTYCQKMQEESISRAIIVVQQ GMTPSAKQSLTDMAPRYILEMFLESELLINITEHQLVPEHIVLTADEKKELLQRYKLKDN QLPRIQSSDAVARYYGLTKGQVVKIVRPSETAGRYVSYRLVVDKKDSVGTVIGIDLGTTY SCVGVYKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTIFDVKRLI GRRFNEPSVQQDIKFYPFTVTNKNDKPYVQVKVGEETKTFAPEEISAMVLIKMKEVAEAY LGKKVTHAVVTVPAYFNDAQRQATKDAGAIAGLNVMRIINEPTAAAIAYGLDKKEGEKNI LVFDLGGGTFDVTLLTIDNGVFEVLSTNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRS NNRAVQKLRREVEKAKRVLSSQHQAKIEIESFFDGDDFSETLTRAKFEELNIDLFKSTIK PVQKVLEDADLKKDQVDEIVLVGGSTRILKVQQLVKDFFNGKEPSRGINPDEAVAYGAAV QAGVLGGEEDTGDLVLLDVNPLTLGIETVGGVMTKLIGRNTVIPTKKSQIFSTAADQQPT VSIQVYEGERPMTKDNHLLGKFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGN KNNIVINNDQNRLSPEDIDRMINDAEKFAEDDKKVKEKVEARNELEGYAYSLKSQIGDKE KLGGKLSSDDKETLEKAVEEQIKWLEKNHDAEAEEFKTHKKQLEDVAQPIVSKIYQQAPP PTQEEDRDELDTSSEDPELEAIKARVREMEDEAEKIRAMQSEVEKQMTEADKLEADARSI WIGNVDYGTTAEELEAHFHGCGSVNRVTILCDKFSGHPKGFAYVEFANIEAIDPAMALND SLFRGRQIKVTCKRTNKHGLTSTNRPPRGRGMRARGGGQYPSYSPRVGRGGYGRSRRPHY YSPYVILATSEEMRYKGTFETLKLRNQMERTALENGPKLIIQEMQYQEKCKKLIESIIDE KEQGQMMIKEREAQVASLKDYLKEQKVLRAYEMSYIKKFSEASLEQLKKMNDKQIWLLQE DERKVQQLIENDIKANEVMESFLKKEIESYQELLNWWTSKYEIDVEKKTAELKELKERRE KDLEWQETLKKRIVEYEQVIEDDR--RMKAIKQAEEDFMKLKKAIQIQAWWRGLRVRRCL GPFKKKKQKKPKIGINGFGRIGRLVVRVAIEKVEVVAINDPFIDLEYMVYMFKYDSTHGK FKGEVGLIINGHHISVHNSKDPSAIPWGADGAEYVVESTGCFTTVEKASAHLKGGAKKVV ISAPSADAPMFVMGVNEDGYKKEYNVISNASCTTNCLAPLAKVIHDKFTIIEGLMTTIHS YTATQKTVDGPSNKDWRGGRTAAQNIIPSSTGAAKAVGKVIPALNGKLTGMAFRVPTPNV SVVDLTARLEKAAKYDEIKAAVKGPLKGILGYTEDQVVSTDFNTSSYSSVFDAGAGISLN DHFVKLVAWYDNEYGYSNRVIDLINYAFKVDQDDLATAILRRKAKPNRLLVEEAISDDNS VVSVSQAKMDELQLFRGDSVLLKGKRRREAVCIVLSEEGLSDEKIRINRIVRNNLRVRLG DIVSIQSCTDVKYGKRVHILPIDDTVEGLTGNLFEVYLKPYFLEAYRPVHKGDIFLVRGG MRAVEFKVVETDPSPYCIVAPDTVIHCEGEPVKREEEEEALNEIGYDDIGGCRKQLAQIK EMVELPLRHPQLFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSK LAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQ RAHVIVMAATNRPNSIDAALRRFGRFDREVDIGIPDTTGRLEILRIHTKNMKLAKDVDLE RVAAETHGHVGADLAALCSEAALQQIREKMDLIDLEDDAIDAEVLNALAVSQEDFRWALS KSNPSALRETAVEVPNVTWEDVGGLENVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFY GPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFD ELDSIAKARGGNVGDGGGAADRVINQLLTEMDGMSSKKNVFIIGATNRPDIIDSAILRPG RLDQLIYIPLPDEKSRVAILKAGLRKSPVAQDVDIDYLAKVTHGFSGADLTEICQRACKL AIREAIESDLRRERDQENKPDDYDPVPEIRRDHFEEAMKFARRSVTDNDIRKYEMFSQTL QQSRGMGSGASGSFGQSALN----FNNPSKDIEIPSPPDDSISSLKFSPATLSSTFLAAG SWDNNVRCWEVQQNGTSVPKAMQAHAGPVLDVCWSDDGSKIFTASTDKSAKMWDLASNQF VQVAQHEAPVKTVHWIKGSSYSVLMTGSWDKTLKFWDTRTPNPILNIQLPERVYCADVLY PMAVVGTAGRQVIIYQLDNHPQEFKSLESPLKYQHRCVSIFCERKPALPVGFALGSIEGR VAIQYVNPVNPKDNFTFKCHRSNHQDIYAVNGIAFHPVHGTLATIGSDGRFSFWDKDART KLKTSDPLDQPITTCAFNAQGTIFAYAGSYDWSKGHEGYDPSKMKPRIYLRSCFEELKQS NKKMSSPSPGKRRMDTDVVKLIESKHEVTLLGGLHEFVVKFYGPTGTPYEGGVWKVRVDL PERYPFKSPSIGFMNRIFHPNVDEVSGTVCLDVINQAWTALYDLSNIFESFLPQLLTYPN PTDPLNGSAAALYLHRPEDYNKKVQEYVQKYATEAALREQESSLSDFSEDETQQMELMEE GDILTTLKILIIGESGVGKSSLLLRFCEDTFDPDQSATIGVDFKVRTLIVDGNKAKLAIW DTAGQERFRTLTPSYYRGAQGCILVYDITNRQSFLKLENWLTELETYSTKHEIVKMLVGN KIDKEKREVSREDGLTFARKHHMLFIEASAKTKEGVQCAFEELVEKIIQTPGLWETDGFS LSQVIWSIVNGSHCSFKICTKTQKFCRNEYNLTGLCNRRMCPLANSRYATVREEKGVCYL YMKTIERSAFPARLWEKVKLSKDFEKSLKQIDENLIYWPKYIIHKCKQRYTRVMQYLVQI RKLTLKRQKKIVPLSQKVERRENRREEKALVAAQLDNAIEKELLERLKAGKYGEIYNFPQ HSYNQAMEQLEVDEDNELEGEREFV--EDFDESDLSDVELGQMRVSASPKMKKFKVYRYD PDKPGDKPHMQTYEIDLNDCGPMVLDALIKIKNEVDPTLAFRRSCREGICGSCSMNINGA NTLACLCPIDNNLGKTTKVYPLPHMWVIKDLVPDMNNFYAQYKFIEPYLKKKNFNEEDLG KKSFLQSPEDRAKLDGMIDCILCACCSTSCPSYWWNGDKYLGPAVIMQAYRWIMDSRDDF KHERLAQMRDEWSLYRCHTIMNCTKTCPKGLNPGAAIGEMKKVMLGYASHGIPKQEAKPN HTIYVNNLNEKIKKDELKKSLFAIFSQFGEILDIIARKTLKTKGQAFVIFKDINSSTNAL RSMQGFPFYDKPMRIQFSKKDSDIIAKMKGTFIERPKRLYISDGKKKRKGANPALIPDQP PHYILFLTGLPEETNNIMLQMLFQNFPGFKEVRLVPGRHDIAFVEFENEYQAGVAKESLQ GFNLTPTSKMKITFAKKMDSKGRQVVVCDNGTGFVKCGFGGTNFPTHIFPSLVGRPILRS KAKIGNIVVKDLMIGDEASELRSMLEVSYPMENGIVRNWDDMIALYKYTFGPDKLNIDPT NCKILLTEPPMNPLKNREKMAEVMFEQFNFQAIYIAIQAVLTLYAQGLLTGVVVDSGDGV THICPVYDGYALPHLTKRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRIMKEKLCYV GYDIELEQKLALETTVLVEQYTLPDGRVIKVGGERFEAPEALFQPHLINVEGVGIAELLF NTIQAADIDTRPDFYKHIVLSGGSTMYPGLPSRLEREMKQLYLERVLKGDTERLTKFKIR IEDPPRRKHMVFMGGAVLAKIMKDKEDFWMTRQEYQEQGVRVLSKLSPSMTSCVGKIIEC LAAVAWQANEPLKIEKVSVAPPKAGEVRIKILHSGVCHTDAYTLGGHDSEGVFPVILGHE GGGIVESVGEGVTEFEIGDHVIPLYIPQCKECKFCLNPKTNLCQKIRVTQGRGVMPDGTS RFTCNGKTIYHFMGCSTFSEYTVVASISLCKIPKEADLQKVCLLGCGISTGFGAVFNTAK VEKGSVCGVWGIGAVGLAAIMGCQKAGASKIYAVDINEKKFDLAKKFGATHVINPANYNK PMQEVLVEMTDGGFDYTFECIGNVQTMRSALEACHKGWGVSVIIGVAAAGQEISTKPFQL VTGRTWKGTAFGGYKSKDCVPLLVNKYLGKELEIDDFVTHTMELNDINKAFHLMHTGESM DAFSVLANQPLVIDNGSGIIKAGFAGDQMPKCHFPNYVGRPKHVRVMAGALEGDLFIGPK AEEHRGLLSIRYPMEHGIITEWNDMEKIWEYLYSKEQLYTFSEEHPVLLTEAPMNPRRNR ERAAEIFFETFNAPALYISLQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGYALPHSIL RSDIAGKDVSKYLRLLLRKEGFDFHTTAEFEIVKGLKERICYLATSPLKEESADTEKVQY QLPDGQVIEVGSSRYRAPELLFRPDLVGEEYPGIHEVLTSAIQRSDVDLRKMLYSNVVLS GGSTLFKGFGDRLLNEMRLLAPKSTKIRISAPQERLFSTWIGGSILASLDTFKKIWVSKK EYENDGAKVIHRKTFDSSKISKVVVHPLVLLSVVDHFNRMGKVGNVKRVVGVLLGANRQG VLDVSNSFAVPFDEDPKEQDVWFLDHDYLENMYSMFKKVNAREKIIGWYHTGPKLQQNDV IINELIRKYVTNSVLVIIDAKPNQVGLPTEAYYAVEEVHDDGTPAAKTFEHVASEIGAEE AEEVGVEHLLRDIKDTSVGTLSQRITNQLTGLRGLKMQLGEIHSYLEKVCSGTMPINHQI IYLLQDVFNLLPDINLQSFVRSVYVTTNDQLLVVYISALIRSIIALHNLINNKVQNRDSE KNEGAKDSMGLLFAKFWSLFSSEEHKVIIVGLDNAGKTTILYQFLMNEVVHTSPTIGSNV EEVLWKNIRFIMWDIGGQESLRASWSTYYSNTEFVILVIDSTDRERLSITKEELYKMLAF EDLKKSFLLVYANKQDLKGAMTAAEISYQLNLTSIKEQGWHIQGCCALTGEGLYQGLDWI GSRIKRKKILIKKVQITDHAQLPSNYSATPGGTIFSTTPGGTRIVYERDFLLQCRNSTLS MTPPTNLPIIPGVTRPPPPGKRKEIYKYEAPWTCYSMNWSVRPDRRFRLALGSFIEEYNN KVQILSLDEETSDFICRHTFDHPYPTTKIIWIPDTKGAFSDLLATSGDYLRVWRVTKMEC LLNNNKNSDFCAPLTSFDWNEVDPNLLGTSSIDTTCTIWGLETGQAIGPVTGHVKTQLIA HDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHLPLLRLAWNKQ DPNYLATMAMDALEVIILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQAL IWDIQQMPRAIEDPILAYTASGEINQIQWSSMQPDWIAICYNNCLEILRVKNFSFSSKVA VLGASGGIGQPFSLLLKLNPHITQLALYDIVHTPGVAADLSHCSTNAVVTGHMGPEQLKD ALTGCDVVTIPAGVPRKPGMTRDDLFNTNASIVRDLANACAKYCPKAMICVIANPVNSTV PITCEVFKAHGVFDPRRIFGVTTLDIVRANTFIAQAKGLDVAHFNCPVVGGHSGITIIPL ISQCNPPVSFPQEERAAITTRIQNAGTEVVEAKAGAGSATLSMAFAADKFVTSLLQALSG EDGVVECAFVASEETEAKYFSTPLLLGKNGVEKNLGLGKLSEFEIGLVKNAIPELQKNIK KGEEFLLKNIDRGKDFNIKTRTITDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFAS TLSHLRRLNSPIGRDGKLARPRQLHNTLWGMICPAETPEGCAVGLVKNLALMAYISVGSQ PSPILEFLEEWSMENLEEISPSAIMDATKIFVNGCWVGIHRDPEQLMNTLKKLRRQMDII VSEVSMIRDIRDREIRIYTDAGRICRPLLIVENQKLLLKKRHIDLLKEREYNNYVWQDLV ANGVVEYIDTMEEETVMLAMTPEELVEKGVLYCTTYTHCEIHPSMILGVCASIIPFPDHN QSPRNTYQSAMGKQAMGVYITNYHVRMDTLAHVLFYPQKPLVTTRSMEYLRFRELPAGIN SITAIASYTGYNQEDSIIMNESAVDRGFFRSVFYRSYKDAESKKGFDQEEVFEKPDRSYV QGMRNASYDKLDDDGIISPGIRVSGDDALIGKTITLPENEDELEGQARRYTKRDNSVFMR KSETGVVDQVMLTINQDGYKFCKIRVRTIKTPQIGDKFASRHGQKGTCGMRYRQEDMPFT AEGISPDIIINPHAIPSRMTIGHLIECLQGKVAANRGEIADATPFNDTVNVRKISDVLKE YGYHMHGNEVLYNGHTGRKMVSQIFIGPTYYQRLKHMVDDKIHSRARGPVQILNRQPMEG RSRDGGLRFGEMERDCQIAHGAAQFLKERLFEVSDPYPVHVCNLCGLICIANLRNQNFEC RGCKNKTQISQIRMPYACKLLFQELMSMSIAPRMMVILDELNGGFSFENCRRNAVLAQGF KHPKATKTGTTIAGVVFKDGVVLGADTRATSDTIVADKNCSKIHRIADNIYCCGAGTAAD TDRTTKMIESNMELIRLNTGRTPRVVAANRMIRQFLFRYSGHISAALVLGGVDVTGPHLL SIHPHGSSTSLPYVTMGSGSLAAMAVFESRYKINMERQEAMQLVHDAIAAGIFNDLGSGS NVDLCVITKKTEYLRPFNVATKKGVRQGDYTYKKGTTVVLSETVEYIEEDTMMTKVTFKI ILTSDPKLPYKVLSVPEQTPFTAVLKFAAEEFKVPSETSAIITNDGIGINPAQTAGNVFL KHGSELRLIPRDRVGHMAFSFVAFCYIIALIFTAILIFFVIYQIIAFDELKTDYKNPIDQ CRSLNPLVLPEYGLHAFFVLLFIITFEWITVVLNLPLLFYHIHRYMNRPVMSCPGLYDPT TIMNADELSRGNREGWIKLAFYIITFFYYLYSMIYVLVSSMGLMTIIKKLKQKEREIRLL MLGLDNAGKTTIVKKFNGDDISTISPTLGFSIKTIEHRGFKINFWDVGGQTSLRTYWRNY FESTDGLIWVVDSADKRRLQDCKKELDQLLVEERLAGATLLVFANKQDLDGAVSSETIME ILDLENLKTHHWMILGCSAVTGDNLLKGVDWLIDDISSRIFTLDHSKRKICYYYDGDIGN YYYGQGHPMKPQRIRMCHNLLLNYGLYRKMEIYRPHKASQDEMTRFHSDDYIKFLKSIRP DNMSDFNKQMQRFNVGEDCPVFDGLYEFCQLSTGGSIAGAVKLNKQATDIAINWSGGLHH AKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTMSFHKY GEYFPGTGDLRDIGAGKGKYYAVNFPLRDGINDESYEQVFQPVMSKVMEMFQPSAVVLQC GADSLSGDRLGCFNLSLKGHGKCVEFVRRFNLPTLMVGGGGYTIRNVARCWTYETSIALQ TEIANELPYNDYFEYYGPDFKLHINPSNMTNQNTTEYLDKIKSRLFENLRMLPHAPGVQM ADIVDDALKEEQNPDERISIRASDKRIACDDEFSDSEDEGDGQKKNKESNRTKRMTSGAF ECNICLDTARDAVVSMCGHLFCWPCLHQWLETRPSRKTCPVCKAGISKSKVIPLYGRGNT NHQDPRDKVPPRPQGQRSEPENTNSFPGFGFGFQMSFGIGAFPFGFFASTFNQGDGRNQN GI--NAPHPDERFLNRVFLIIALLFLFWLMMAMYSLCYKQENAHDDSIWSCTW--TAKND QQYIVTGSISDHVKIWQWKDLEVKHSLEGHQLGVVSVDADSSGELAASSSLNSNIRIWEI ESGKSLQSIDAGPVDAWTIKFSPDGKHIATGTHTGKINLYAVESGQKESQLDTKGKFMLS VAYSPNGQYIACGAIDGFIYVLDVQTSRLLEGHAMPVRDLTFSKDSTHLITASDDNYIKV YDVHQATAICSLSGHGSWVLGVDFSPDNNHFASSSSDRTVKIWDLKNRVCEHTFTDHTDQ VWSVHYNQKGDQLVSVSEDKSILIYDCPIESEAEFDNRYERFFNNSKIDGWEIRKGINDL HGYDLVPEPKIIVAILKACRRVNDYALAVRYLEAVKDKCGPNVGKIWPYLLKEIGPTLKD LGVLTPEEMGYDKPELALKDVHDMIVRLRGLPWSVSNEEIINFFEGCSL----ADINLLY NKDGRPSGEAFVELSTTEDMDIALSKHREYMGRRYIDVFSATRNEMEWTLRKNGMPRDAV VKLRGLPYSCDKDTLVNFFEGLPITPNGISLMTDPHGNATGDAYVQFANQKFADVALKKH KERIGHRYIEIFRSTLSEARSNYISQTGYSIHMRGLPFSATESDVMEFFYPTTPVNIEIE LNQGRPSGNANADFMNKYDADQAMKKDRQSIKHRYIELFYKDKDKPTQIRYSNITAAKAV ANAIRTSLGPRGMDKMIQTGKGEVTITNDGATILKQMQVLHPAAKMLVELSKAQDVEAGD GTTTVVVVAGSLLDAAQRLLQKGIHPTTISECFQSAAAKACSILENMSMPVQLSDRESLL KSATTSLNSKVVSQYSNTLSPICVDAVLKVIDPVKDTNVDLRDIKIIQKLGGTIEDTELI DGLVFNQRAAGQGGPSKVEKAKIGLIQFCISPPKTDMENQVIVSDYTQMDRVLREERQYI LNIVKNIKKAGCNVLLIQKSILRDAVNDLALHFLAKQKIMVVKDVEREDIEFVCKTIGCR PIASLDHFQPDMLGAAELVEEVQAGDSKLVKVSGIQNAGKTVTILVRGSNKLVLEEAERS IHDALCVIRCLVKKKAIIAGGGAPEIELSLRLMELSESLVGMEQYCFRAFAEALEVVPFT LAENAGLNPIGTVTELRNRHARGEKMAGINVRKGTITNILEENVVQPLLVSTSAIHLAAE TVRSILKIDDIVICMMILLEINNKIIEDTLSLKFANAAAGVKHELIEVTIADFDGVLYHI SNPNDDKSKIMVSISLKFYKDLQEHGADDLIKREYGQLLTTNEKGYNVSILFDNNLPANK EEAIKKAGLLKRNCFASVFEKYFEYQQKQKRAVINYRDDETMYVEAKKDRVTVIFSTVFR DVDDVIIGKVFMQEFKEGRRQYQQAPQVLFNHKEPPLELQNTSAKTGDNIGYITFVLFPR HAARDNTINLIHTLRNYLHYHIKCSKAYIHAMMRAKTNDFLKVLNRARPEPKTVEKKIIM LLFCPNCFNALVLAEKNGRNRLLCLTCPFFHEIVKKITFKKYTKLKDVEDALGGPDAWKN AQATNETCPSCEHTRAFYMELQTKSADEPTTVFYRCC--ECAHVWKKTKFGNLKDEDRVF TNLYGRHDWRLKGALKRGDWYKTKEILLKGTDWIQGEVKKSGLRGRGGAGFPTGMKWSFM NKPNDGRPRYLVVNGDEGEPGTCKDREILRHDPHKLIEGCLIAGRAIGARAAYIYIRGEF YNEASNTQLAIKEAYEAGLIGKNACGSGYDFDVYLHRGAGAYVCGEETSLIESIEGKAGK PRLKPPFPADIGLFGCPTTVNNVETIAVAPTICRRGGDWFASFGRPRNRTVLMDFDDLTA NHSAFGTAAIIVMDKRNDVIKCIARLAHFYKHESCGQCTPCREGCNWMSKVMDRFVLGKA RPEEIDMLYEMSKQIEGHTICALADGAAWPIQGLIRHYRPEIEGRMKEYAAKHYMQEQIN DMNQQLTQTRSQRVRAAMFPETFDEEIQIPSTQKHFGQMTTVQRLAEPSRMLKHAVVNLI NYQEDADVAVRAIPELISLLNDEDQIVVGHAALMSHQLSKKEASRHALLNSPQIIAALIN ALNKAKDPETIRYLTGALHNLSHHQQGLLYIFKSGGIPALIRLLSSPIESILFYAMTTLH NLLLHQEGAKMAVHTAGGLQKMVALLTYDDPKFLAITTDCLQLLAYGNQECKLIILASGG PDNLVRIMERYNYEKLLWTTSRVLKVLSVCPSNKVAIVEAGGIHVLSNLLVNPSTRLVHN CMWTIRNLSDSATKLEGMEPVLEVCVRMLQMDDLDMIICSCGILSNLTCNNHANKSYVYQ ISGVEALVATVVKAGDREDITEPSVCALRHLTSRHAHAELSQNLIREEGGLMPIINLLHP PSHWPLLKATVSLVRNLALCEKNNPELRGLGAVPKIIQLLVRSHQEVQKSDGIMMDAVRM DEMVETCVGALHILARDVHNRTIIKEHNCIPLFVQLLYFPHENTQRVTTGVLCELAAEKD AVEMTEQEGATAPLTELLHSHNEAVATYAAAILYRMSEDKSADYKKRLSIELTNSLVRGD PMSSDLQWMIVRNSSSFLMKRRTFSKERNNLKGLNSYRFNGLIRKKTIGVEPLPDGKGVA IITKSAHRKLPRQYTKVELKRGARRTLKSIKSIVRNGKYRKDLKSAALRRASAILKSQKP VVPKKIRDEPYYCSQQIKIPPDLPDVLKQFTKAAIRTQPQDVLAWSAAYFSAMANGEIPP VKDRLEMPSASLKTDTGLTKGLLKVLNRQLGPKKVVPISMIENKWLDLTMPKELFDDLVR IGNFTGYVQWSEFLALAASSIASDITGAMRNICEIVTHDAEGGASKIPFILFKNLYKYLA NIDGDISTEDMNAVEEYLQQYSKKQDGYIMPRNFENELCPNLAGKLDSNQKQQLMEQVKA QIAVANAQELLQKMSDKCFKKCIPKPGSGLDNSEQKCIAMCMDRYMDTWNIVSKTYTQRL QKEKSKMMNRLFGSSAKKQPPPNMTDCISNLDSRSESVDKKIARLEQELAKYRDQMKKMR EGPSKNLLKQKAMRVLKQKKMYEQQRDNMTQQSFNLEQANYNIQSLKDTQITVSAMKTGM KEFKKEFKKININSIEDLQDQMEDLTEQSQEIQEIMGRSYGMPEIDDDELEAELNALGDE IALDDDTSYLDEASKAPNAPTSVPGADSVVNKDGVPVDEFGLPKIPAQLTSLNPTTPASP QLQNIVCTVNLGCKLDLKKIALHARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTG AKSEGLARLAARKYARIVQKLGFSAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHAQFSSY EPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKERTEINEAFENIYPILKGFKKQDEDDD DGFDAHHIETKPLGDEDEEDYLHEVLSPDEVVKHMNDCIKEVNVILQLPTTITRILLNHF KWDRDKLMERYYDDDQDKLFADVRVVSPFKMPIKVRFNVIFVG-PYLMTGLQCGHTFCAS CWSKYLTTKIMDEGMGEMISCAAHGCDILVDDEMVMKLVTEPNVKLKYQQLITNSFVECN RLLRWCTAPNCSFVIKVQHSDARPVRCKCGNVFCFACGENWHDPVQCKWLKRWIKKCDDD SETSNWIAANTRECPKCHATIEKDGGCNHMLCKRCKFDFCWVCLGPWEPHGSSWYNCNRY DEDAAKKARDAQEKSRAALQRYLFYCNRYMNHMQSLKFEHRLYTSVSQKMEEMQQHNMSW IEVQFLKKAVDVLCQCRQTLMYTYVFAFYLRKNNQSIIFEDNQKDLENATEQLSEYLERD ITSEILVDIKQKVQDKYRYCESRRKVLLDHVHEGYEKDLWLYQDMAATECNLPTKERVVK GVPFPPTQRLTLSEVMDSKGRPRPEVLKQHFILEGRITEEAALKIINEGAALLRQEKTMI DVSAPVTVCGDVHGQFYDLMKLFEVGGSPATTRYLFLGDYVDRGYFSITEKVYEACMESF DCLPLAALMNQQFLCVHGGLSPEIHTLDDIKKLDRFREPPSFGPVCDLLWSDPLDEFGNE KTTEHFSHNSVRGCSYFYSYAACCEFLQQNNLLSVIRAHEAQDAGYRMYRKSQATGFPSL ITIFSAPNYLDVYNNKAAILKYENNVMNIRQFNCTPHPYWLPNFMDVFTWSLPFVGEKVT EMLVSVLNICSDAELENTDD----SSVAARKEIIKNKIRAIGKMARVFQVLREESESVLQ LKGLTPNGLLPIGALSGGKDSLKLAL-----THKISGFAEAKYLDKMNERMPPWKEFSPR GGGGRGRGGGRGGGGRGGYSSGRGG--GGRGGMRGGKKVVIEPHRHQGVFIARGKEDALV TKNMVCGESVYGEKRITVDENSKIEYRVWNPFRSKLGAAILGGVDNINIKPGSKVLYLGA ASGTSVSHVSDIIGPDGLVFAVEFSHRSGRDLINMAKKRTNVIPIIEDARHPHKYRMLVG MVDTIFADVAQPDQARIVAINAHSFLKNGGHAVISIKANCIDSTAPAATVFASEIDKLEQ EKFKRREMLTLEPYERDHAVVIAQYRPPPKKMDKNKISEIMSKLSKNGKGAGVGLGLLAA AGGLLYGVSQATYTVDGGHRAIIFSRIGGIKPDIYTEGLHFRVPWFQYPIIYDIRARPRK ISSPTGSKDLQMVNISLRVLSRPDAMQLPTMYRQLGVDYDERVLPSICNEVLKSVVAKFN ASQLITQRQQVSLLVRKELIDRARDFNIILDDVAITELTFGKEYTAAVEAKQIAQQEAQR AQYIVEKAKQERQQKVVQAEGEAKAAKLIGEAISKNPGYLKLKKIRTAQNIARTIAASRN RVYVQSGSLMLNVSDKEFDENLENTSSSDDDDDDTNPRESIQKTSKGFQDFCVRMQQAAF GRREIEIAEQEMLGLMTLRRKGQTDKPLIGAKIIGCTHITAQTAVLIETLHSLGAQIRWC ACNIYSTQNEVAAALAEAGFSVFAWKGESEADFWWCIDRCIQSDNWQPNLILDDGGDATH LILKKYPAIFGLVKGIVEESVTGVHRLYQLSKSGKLSVPAMNVNDSVTKTKFDNMYSCRE SVLDALKRTTDIMLGGRQVVVCGYGEVGKGCCQALKGMGAVVMVTEIDPICALQACMDGM KVVKLSEVIKSADLVITCTGNKNVVTRDLMDKMKNSCIVCNMGHSNNEIDVNSLRTPDLT WERVRSQVDHIIWPDGKRIILIAEGRLINLSCSSIPSFVVSVTAATQALALIELFNAPAG RYKQDVYLLPKKMDEYVASLHLPSFDAHLTELTDEQAKYLGLSKCGPFKPNYYRYPDSDT IKMFMGQISRSLDEDNLKAYLSEYGQVYEVKIIRDKVSGKSRGCAFVTFYSRKDALTAQM ALHNLITMPGLAHPIQMTPADGANQKVEDRRLFIGKISKHITEEELQSAFTPFGEIEDMF IVREPNDPTRGCAFVTYVHRDSALDAIKHLHMTKVFDSYAEPTIVKFADTQKEKEKKKML QNQQNAQLQFLGGVAGGTASVYIGQPLDTVKVKMQTFPALYNNAFNCFLTTFKKEGYRGL YAGTLPSLENSVLFLGYGLCQKMVALAAFFSSLVLCPTELIKCKLQALTKQVLREEGVKG LFKGLVPTFIREMPGYFFFFGGYETCKILLTPEGQSKDDLGLKTIVCGGVGGICLWTAIF PSDVIKSRVQIRKEGGRSLYRGLGPTLLRTFPATGGLFVAYENTKKYLSSSNNDFLRLSN VISNNIQKIFTNVGQLESIQNQMSTRPDNMELKDKFHQIQHYTNQLARDTTKFLKNLSAI LSEQKQQKLQREKLTGDFAGILNKFQMLQRQEKNIEGEELSEIDQEIMKEREDALVKLES DISDVNQIFKDLGMLVHEQGDVIDSIEANTESANVEQGTEQLSQAQKYNTKARKKKFCLI GTLVIILAIIIIVLAATLSMVYVLKGVLVECDPPMKQLLLKLNETKALGETFVLSDLDDS HLFIDSRFVKALQDKIDETMDKIHFPLGKKGAKTQTPQEAIQRLREVEEMLQKKSNFLEK KVEEEITTAKKRAAIAALKRKKRFEKQLQQVDGTLSTIEFQRDALENASTNTEVLKVMGD AAKALKSAHSHMNVDDVHNLMDDVAEQQEIANEISNAISNPVGFGQDVDEDDLLAELEEL EQEELDKELIKV-DLPSVPNQ-DDDMKELEMWASSLQRFHNRVRQILMASGSTTFTKIVN KWNTALIGLMTYFREAVVSTQELLDLLVKCENKIQTRIKIGLNSKMPSRFPPVVFYTPKE LGGLGMLSMGHVLIPQSDLRWSKQTDVGITHFRSGMSHDEDQLIPNLYRYIMPWESEFVD SQRVWAEYALRTDMIQALGGVEGILEHTLFKGTYFPTWEGLFWEKASGFEESMKFKKLTN ASKDTMDNSTTQKYWLDIQLRWGDYDSHDIERYTRAKFLDYTTDNMSIYPSPTGVLIGLD LAYNLHSAFGNWFPGCKPLIQQCMAKIMKANPALYVLRERVRKALQLYSSEPTEPYLSSQ NYGELFSNQIIWFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSV WAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKG SELQLPFQACLKVEKFGDLILKANEPQMYLFNLYDDWLKTISSYTAFSRLILILRAMHVN NDRTKMTLKPDRTTITETHHIWPTLNDEDWMKVEVQLKDLILADYGKKNNVNIASLTQSE IRDIILGMEISAPSQQRQQIAEIEKQTKEQSQLTATTTRTVNKHGDEIITSTTSNYETQT FASKTEWRVRAISATNLHLRTNHIYVSSDDIKETGFTYILPKNLLKKFIIISDLRAQIAG YLYGVSPHDNPQVKEIRCIVMPPQWGTHQTVHLPNILPTHDHLKQMEPLGWIHTQPNELP QLSPQDISTHARIMSDNPSWDGEKTVVITCSFTPGSCSLTAYKLTPSGYEWGRQNKDTGN NPKGYLPSHYEKVQMLLSDRFLGFFMSPVQSSWNFNFMGVHHDPNMKYEIQLANPKEFYH EIHRPSHFLNFRSLEDGADREDLFLAYDATRANLMVSKSTKVICQGFTGKQGTFHSKQAI DYGTLMVGGVSPGKGGQTHLGLPVFNSVKEAKEATGCDATVIYVPPPVAAKACMEAIDAE IPLIVMITEGIPQHDMVRVKRRLMDQDKSRLVGPNCPGLIKPGECKIGIMPGHIHTAGKI GVVSRSGTLTYEAVHQTTLTGLGQTLCVGIGGDPFNGTNFIDCLDVFLKDPKTEGIILIG EIGGQAEEQASEFLKEFNGPNRKPVVSFIAGLSAPPGRRMGHAGAIIAGGKGGAKEKIEA LKSAGVEVTMSPAQLGSTMVKAFEKMGKQNLENLRCTICLERLEDTHFVQCPSVPEHKFC FPCSRESIKRQGCGSEVYCPSGRKCPLVGSSIPWAFMLNEIETILGFKRFVEIGRVAYIA FGPDEGKLVTIVDVIDQNRALVDGPCTSVVRQAMNFNKLELTKFVIFPHSARTGVVKKAW EKADINKLWSETSWAKKIEAQNKRKVMTDFDRFKLFKAKQARNRLVRIEFGRLRKLAKQT CPLLLRVFCNTGRHNQLTEYSRGKTPMNELQVYTWLDATLKELTNLVKEVNKEARVKGTY FDFGIVYPDSRSPAYKFRDIGSTCSGKKGLDDNVTLASRNFQIGDYIDIAITPPQGLGKT LQTISLLGYMKHYRHTSGPHLVITPKSTLANWEAEVKKWVPTLVAVCLIGGQDERANLIR DVILPSEWDVMITSYEMVIKEKALLKKYNWRYMIIDEAHRIKNEKSKLSEIVREFKSANR LLLTGTPLQNNLHELWALLNFLLPDVFNSSDDFDSWFNTNTCLENAQLVERLHAVLRPFL LRRIKSEVEKRLLPKKETKIYIGLSKMQREWYTKILMKDIDIVNGAGKTDKMRLLNILMQ LRKCCNHPYLFDGAEPGPPYTTDRHIVDNCGKMVLLDKLLPRVKEQGSRVLIFSQMTRML DILEDYCLWKGYEYCRLDGQTPHEERQESINAYNQPGSTKFIFMLSTRAGGLGINLATAD VVVLYDSDWNPQVDLQAMDRAHRIGQLKQVRVFRFITDHSVEERIVERAEMKLRLDNIVI QAGRLVDQNTHKEMLSMIRHGADHVFASKDSEISDENIDAILERGEKKTEEMNKKLDELG EGTLRTFTLDQPTSSVYQFEGEDYREKHKISGITHWIEPPKRERKANYAVDAYFREALRV SEPKAPKAPRPPKQPTVQDFQFYPPQLFELLDKEIYFFRKSIGYRVPKDPDHGADAEKIR REEQKKIDDAEPLTDEEIALKDELLRGFSTWTKRDFNQFIKANEKYGRSDLESISKEVEG KTPAEVMEYASVFWERSNELQDIDRHLAQIDKGEHKIQRRLSIKRALDLKIARYKAPFHQ LRISYGTNKGKNYTEEEDRFLICMLHHLGIDKENAYDQLRASIRQAPQFRFDWFIKSRTA AELQRRCHSLITLIERENAELEEKEKQDRGKDVKPSWAEQVELGDEDTLPPPTETFDEKT GVKKVIEYKINDDGKKVKVIKTYKVETYKVSKTIAKRKTWKKFGDAKNDPPGPNPANTVE DIFLQFVHAKELPEDDPLSRLKVSCRICKGDHWTTKCPYKERLAPLQETLAKPGKYVPPS LREGGNKKGDSMSVDDSATIRVTNLSEDTRESDLQDLFRPFGQISRIFLAKDKLSGQSKG FAFINFHHKEDAARAIAGVSGFGYDHLILNVEWAKPSMTETYDYLFKFLVIGSAGTGKSC LLHQFIENKFRQDSSHTIGVEFGSKVVSVGGKFVKLQIWDTAGQERFRSVTRSYYRGAAG ALLVYDISSRETFNSLVNWLSDARTLASPNIVIILVGNKKDLEAEREVTFLEASRFAQEN DLMFLETSAMTSENVEETFLKCARSLLTKIETGEMDPERLGSGIQYGNASLKRLQPSTQR CSCMIQPSGRSKLETSQWPLLLKNFERLNVRTNHYTPIPAGCSPLLRPIDEYIKSGIINL DKPSNPSSHEVVAWIKRILRVEKTGHSGTLDPKVTGCLIVCIDRATRLAKSQQGAGKEYV GIFRLHEAVENEKQILMAVQSLTGALFQRPPLISAVKRQLRVRTIYDSKLVEYDKGRNMG IVWVSCEAGTYIRTLFVHLGLLLGAGGQMQELRRVRSGIMSENDSLVTMHDVLDAQWVYD NHRDESYLRRVIRPLESLLISHKRIILKDSAVNAVCYGAKILMPGVLRFDDGIELNEEIV VITTKGEAVAIAIALMTTAVIASCDHGFVAKIKRVVMARDVYPRKWGLGPVAAKKKDMIK SGLLDKHGKPTAATPKNWIQAYTDFSDKKKKLKEQADVEEKKEKKKKKMAECDWDRKKAP KSNQLKTQQAINAAQRQGLEIETSKKFNAGHNKQHVGDKNTAKLDRETEELHHETVGLDV GRLIQQGRQAKNLTQKDLATKINEKPQIVNEYENGKAIPNQVILGKMERILDIKLRGKEK GQSLHAKIFKPKVLTQVLSSANSDGVLCTLLLSGDGSLMAYTGYDSKNARDIAAIANNIW MHLSKNLKFTSDLDELDSVLINCQEGNVIVSRVANFLLCSYSNKDVELGLLRSKAQALVS FLQEPMKSVVAATAATARIQPKKQTLDDAYAPPANFLEIDVINPEGKKRYTDYEIRMKTN LPVFKIKESSVRRRYSDFDWLAAELERDSKIVVPMLPGKAWGRQLPFRSDDGLFDEEFIE ERRKGLEIFINKVAGHPLAQNEKCLHMFLLEPTIDKNYIPGKVRTTRRYATKLAEVGVLE TPKSQGKYETGQLFLHKVFGYRGVVLFPWIGKIYDRDLAFKINKDVKAKILTYYQVLMDT RDSPHVRVGTETVTFLSNQDNSTLYSIPGLDYIAHEDILPYKTSDEQPIKNHLFQKFFSS AVVLMARESLQDWQSKNYAWLELTDIHRETTKNIRVTVMPFYIGEVQQTRVYWWRYCIRI ENLGDESVQLRERHWRIFSLSGTLETVRGRGIVGQEPVFTKSQPAFQYTSHVSLQAPSGH MWGTFKMEKSDGSSFECRVPPFSLESKPEDNMAMSKSANTYNRQNWEESEFPILCQTCLG DNPYLRMTREKFGKECKICARPFTVFRWCPGARMRFKKTEICQTCSKTKNVCQTCLLDLE YGLPVQVRDAALNIRGEIPTSDVGREYYTQKMERELANTDGTTPAGALGKARAKSEMLMK LARTTPYYKRNRPHICSFWVKGECKRGEECPYRHEKPTDPDDPLADQNIKDRFFGINDPV AEKLLRRYNEFPDADENEDMDVFLMVRRKNVTLFLDAKESTTVIELKKIIKGILKKNLDE ILLYKDTKTLGDVGYTSVTAKAQAPATIGLVFKTFEPLEITELSTPPDLPEVMKPQETAA SHAQEHLYRYEAVLLRDRFDQNKNEDMVKAKQMLEDGEKELFENLHPQPFKFPNSPGGIA FEREVYYPDWMLDMWHPLERLQYPEYFKKREQRKLEYIDRWEKKYGKAEIDDYAKIEKIG EGTYGVVYKGRHKASGRFVAMKKIRLDSEEEGIPSTAIREISLLKELVHPSIVTLEEVLM QEGKLYLVFEFLSMDLKKYFDSLPIEKLMCPNLIKSYMQQILEALLFCHRRRIIHRDLKP QNLLIDAKGMIKLADFGLARAVCIPMRAYTHEVVTLWYRAPEVLLGCPRYCPAVDIWSVG CIFAEMASKKPIFRGDSEIDQLFRIFRTLTTPTEENWPGVSEMPDYKATFPSWKVNNLRQ AADDDALDLLEGMFIYNPTKRISAVTALKHKYFAGRLFNLLGKVGIGLAVAGGVANSALY NVDGGHRAVIFDRFAGVRQEVVGEGTHFIIPWVQKPIIFDIRSQPRSVPSITGSKDLQNV NITLRILYRPLVSKLPQIYMNLGIDYDERVLPSIVNEVLKAVVAQYDASELITQREMVSQ KVTEELTNRAAHFGVMLDDISITHLTFGREFTEAVEMKQVAQQDAERARYIVEKEEQLKL AAIIRAEGDSIAADLLAKAFAESGEGLVELRKIEAAEDIAAQMSQSSNVVYLPQGQNTLI GLPMKTINQNQTVKIPDGISISVKSRKVIVKGPRGTLRRNFTHMAVDIRKVNAKEIMVEK WFGIRKELAAVKTVCSHIENMIKGVTKGFRYKMRSVYAHFPINVSISENNSLVEIRNFLG EKINRQVKMLPGVTCVASKDMKDEFILDGNDIELVSRSAALIQQSTTVKNKDIRKFLDGI YVSEKGTVVQEMGCFHSKDGKRAIERSKQIDLQLKNEQEDSVRQVKLLLLGAGESGKSTF VKQIKIIHENGYTEEECLSYQAVVHNNTIQSLVAIIQAMGSLKIDFSNQERMQDARDFYA MVSSMNDVILTYELGQIMKRLWKDGGVQNCFKRSREYQLNDSAEYFLGALDRISQPNYRP TIQDVLRTRVKTTGIVETHFNLRGLSFKMVDIGGQRSERKKWIHCFEGVTAIIFLVALNE YDLMLAEDQEMNRMTESMKLFDSICNNKWFSNTSIILFLNKKDLFDIKIKTSPLALCFPE YKGRNTPQEAGAYIQKKFNKRRDIKEVYTHFTCATDTSNVQFVFQAVTDIIIKNNLRDCG LFKKFAVKKRIISLKDGRIKKQEREI-KRKKPDPQNMVVREIPQASSALFFKYNEQLGPP YHILIDTNFVNFAISNKLDIIQSMMDCLYAKCIPYVTDCVMGELEKLGRKYRVALRIVKD PRFQRLKCFHKGTYADNCLVNRVTQLKCYIVATCDKELRRRIRKIPGVPIMYITQHKFSI ERMPDDYGAPRMSFSSDEVNYLVYRYLIESGFTHAAYTFGIESHISHSNINGSIVPPAAL LNIIQKGLQYTEAEISIAEDGTERTVEAISLIDAVLPDFIEHKKQGTTTKAG---DKEMM ELDTGIEIPASKSVILKGHESEVFICAWNPTNDLLASGSGDSTARIWNLNESSSANQLVL RHCIQKGGTEVPSNKDVTSLDWNCDGTLLATGSYDGYARIWATDGHLVSTLGQHKGPIFA LKWNKKGNYILSAGVDKTTIIWDASSGRCTQQFGFHNAPALDVDWKDNMTFASCSTDQCI HVCKLGTDKPIKTFQGHTNEVNAIKWDPQGVLLASCSDDMTLKIWSLKQDTCIHDLQAHN KEIYTIKWSPTGPGTNNPNASLILASASFDSTVRLWDVERGVCVHKLTRHLEPVYSVAFS PDGKHIASGSFDKCVHIWSVQTGALVHTYRGTGGIFEVCWNYRGDKVGASASDGSVFVLD LRKSSNDLASLFECPVCFDYALPPIMQCQSGHIVCSHCRPKLQFCPTCRGALGNIRNLAM EKVASQVLFPCRYMSNGCEASLPHTDKANHEDGCEFRPYNCPCPGASCKWQGSLEQVMPH LLQQHKSITTLQGEDIVFLATDINLPGAVDWVMMQTCFGHHFMLVLEKQEKSEGNQLFYT IVQLIGTRKQAESFAYRLELNGQKRRLTWEATPRSIHDGVQSAINSSDCLVFDTNVARLF ADNGNLSINVTINTCMAYQPFQQEYMAIPIGTRVYTTGCVLTTLA-QLELISPFQLYFNP ELVYRHLQLWRVVTTFLFFGTLGFNFLFNIIFTYRYCRMLEEGSFRGRTADFVYMFILGG CLTTFVINLVFLGHAFTIMLVYVWSRRNPYIRMNFLGLINFQAPYLPWVLLGFSLLLGNS IAVDVIGIVVGHIYFFLEDVFPNQPGGFRVLETPKILKWLFDTPSEDENYRPMPPGGYDW GRGLELLSDEQFRADGRRPNEIRRVRCKMGVFKQADGSAYLEQGDTKVLAAVYGPHEAKS GKNKHDQAIVNCQYSMAVFSTTERKQRPRGDRKSTEIGQNLKQTFESAILTHLYPKSQIN IYIEILQADGSNLAASINAATLALVDAGIPMKGLVCCCSAGNVDDTPLIDLNHVEESQGL KLTIAMLPLTEQILMLNMNGRLHEERLEKVMSSAKNGCKEILKDLSQAVRDMSGNYYFVI VGHNDNPIYEIEFLTAAKANDPK--DHKHLNQFIAHAALDLVDEQMWASNSMHLKVVDKF NEWFVSAFVTASRMRFLILHDIKNDDAIKNFFQDAYELFVKHSMNPFYKFNTPIKSSAFD KKVQLIGKRHLPGQIRLAHTDIDFPDFSAYRHDR--DNRKAFSYLMVAAGTIPTTYFAKA MVQELVISMSASADVLAVGKIEVKLDKIPEGKNVTFKWRGQPLFVRHRTAEEIETEQAVD LSSLRHQEHDNDRVKKPEWLVVLGICTHLGCVPIPNKGEYGGYYCPCHGSHYDSSGRIRK GPAPLNLAVPEYAFADDDTLVVGMSRQVARGVDTKKISSELFALTYGSIVAQLVNDYEED DEINKQLDKMGYNIGIRIIEDFLARSGIGRCTDFRETADIISKVAFKMFLGITPVVTNWS STGDEFSLLIENNPLTEFVELPDNHSQLNYSNIICGAMRGALEMVQLDVSVWFVQDQLKG DNITEIRLKFNKRLEDALPPGEDENVKAFLAQAREDFNQKWESPQQNTATLDDFDRIKTL GTGSFGRVMLVQHKSSKEYFAMKILDKQKVVKLKQVEHTLNEKRILQAISFPFLVGLQYS FKDNSNLYMVLEFVTGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKP ENLLIDSQGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVY EMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVN DIKLHKWFTATDWIAIYQKKIDAPFHPKCKGPGDPSNFDDYEEEPLRISSTEKCSKEFAE FMIADTILIVVISIVTALFGEGLTWVLVYRTDKYKKLKNEVEKQSKKLEKQKETVADTSD RNHKKKLERQEEKLKTNNRDLSMVKMKSVFAIGIAFTALL----SIFEGRVVAKLPFVPI SWLQNISHRNLIGEDYTDCSFIFLYILCTMSIRQNIQKMLGFAPSRSANKQSSGFFSSCL KLFLTWNSNQQVQFVQELIQRMDHHQHGEIDTFLQPILQRDFISALPDRGLDHISEKILS YLDSKSLCSAELVCKEWYRVIADGGIWRKLIEKMVRTNTLWFGLAQRKGWMNYLFRPKPG ESHKEHLFYRRLFNEIIKDIDTIDNNWRTGNVALRRILCHSVASKGVYCLQYDDSKIVCG LRDNTIKVWNKSTLECVRSLRGHTGSVLCLQFSDDMIISGSSDATVRVWSITTGEIINIL IHHSEAVLHLRYSEGIMVTCSKDRSIAVWDIISPKEINLRRVLLGHRAAVNVVDFDLNYI VSASGDRTIKVWNTTTCEFVRTLNGHKRGIACLQYREKLIVSGSSDNTIRLWDVECGACL RILEGHEELVRCIRFDNKRIVSGAYDGRIKVWDLQAALDPRSPSGTLCLRTFVEHTGRVF RLQFDEFQIVSSSHDDTIIIWDFMNMAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNS TFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKS FANIKNWIRNIEEHATSDVEKMILANKCDMVERRQVTKEQGQALALENGVKFMETSAKAS INVEEAFITLARDIKIKMDKKLAEGETSADRNVEIWKIKKLIKSLEAARGNGTSMISLII PPKDQISRVTKMLADEFGTASNIKSRVNRLSVLGAITSVQQRLKLYTKVPPNGLVSYCGT IVTDEGKEKKVNIDFEPFRPINTSLYLCDNKFHTEALTALLADDSKFGFIVMDGNCALFG TLSGNTREVLHKFSVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAEVAVQLFIVNDRP NIAGLVMAGSADFKTELSQSDMFDQRLQAKIIKIVDVSYGGENGFNQAIELAAEALGNVK FIQEKKLIGRYFDEISQDSGKYCFGVADTLKALEMGAVEILIVWENLDIIRYVLKNNATN EEKVLHLKPEQEKDKTYFTDAETGVELELVDSVSLLEWFANNYKGFGATLEIITDKSQEG AQFVKGFGGIGGILRYQVDFQGLEALDDLGVDFDLDDYITRSSQPLVGKRSKDDEKYVQM IMDANAQSHKMYIVDARPQPNAIANKAKGGGYESEDTYQNAELIFVDIHNIHVMRESLRK LKEICYHPLDEAHWLSNIESTHWLDHIKQILAGAVRIADKVESNKTSVLVHCSDGWDRTA QLTSLSMLMLDSYYRTIKGFEVLIEKEWISFGHKFAQRIGHGDDKHSDSDRSPVFLQFID CVWQMTIQFPNAFEFNELFLITILDHLYSCLFGTFLGNCELQRKNEKVSERTVSLWSYIN SQLDDFTNPLYKHVLLVVASLRRLRMWNGYYLRWNPQMKSQEPVESRNRELATVEAATAT KLEGLEREYQMKTPNQKTFVPHVTFDIIQCENLFQRVKPPTDDKMFTEALLKKVQELTPN AKTQASVLSLVTSVQTVLDNLVIASGTFDAAVVDEVRQVGNHKKGTLLSGDNVAEIVVVL KTLPTFEAVQSLSNKVYQDMMVSSPREAFGATLNECGFEITNHEAVSRVYVTTIPPNFKF LDASLHLDSKMMEGHLLSIRRTRWFEENACHSTVKVLVRLLSDLRNRFQGFQPLTPWIID VFSHYCVMVNPQRTPLSINIAIRRCLQLLSSGFFLPGSQGIFDPCDKPNVRVHTVMSMEQ QDQVCFTAQTLLRVLSHGGFMYLLGFKKNLDIVNDVTLWNGVVVTPSEKAYEKEDEVIRL IEQFLKENGLTRTLSVLQEETGISLNTVDSVDSFVSDINNGHWDTVLQAIQSLKLPDQKL IDLYEQIVLELIELRELGAARSLLRQTDPMVMMKQQYPDRYLHLENMLSRSFFDPREAYL EGQSKERRRVAIAQALAGEVNVVPPARLLSLLSQSLSWQRHQGLLPPGTTIDVFRGKAAV KEQEEEKYPTQLSRALKFGQKAHVECARFSPDGQYLVTGSVDGIIE-------------- --AQDNFMLMEEAVLCLNFSRDSEMLASGGQDGKIKVWKVLTGQCLRKLDRAHSKGITSI YFSRDNSQLLTASFDMVIKIFGLKSGKALKEFRGHTSFVNDAIFSYDMHQIISTSSDGTI KIWNIKTTECSSTHKSFGGASGVDVTVHSAQLLPKNTEQFVVCNRSNTVVIMNMQGQIVK SFSSGKREGGDFVCCTLSPRGEWLYVIGEDRVMYCFSLLTGKLERTLNIHEKDVIGIAHH PHQNLIATFSEDGILKLWKPMSSAVQAVPKAIATLTPKLNTFWKYAKVELKPPAEWPQVA QGFQNLAKVRTQKWKQLTVKEAAVVATEVICWFFVGECIGKGTLIGYQIKGAVDFDLHSI PKFYTKLPQANELLKQKLRDEGRSAFLQRKSKDLLDNLELQTMWSLLEKYNSPPVLSNEQ MLNYDDFKLVANQVSNKCKQFFRPSIFAKLLTDDPYGRISTLHFFNYIMRKVWLHQTRIA LSLYDAAGLGFLRENDLESYILELIPTLPQLDSLDKSFYSFYVCMAVRKFFFFLDPLHIG KIKIQDVLTCTFLNDLLELRDEEMSKERQETNWFSTLFSFKVYGQYLKLDVDHNGMLSRE ELSKYNNGSLTPAFLDQVFQECLTYEGEMDYKTYLDFVLAMTHRECPQSIQYIFRILDTK HKGYLDVFDLNYFYRSMQEQIQQHILETVSFEDIKNEIFDMVRPMKPNQITCQDLVKSGQ ASTIVGLLIDVNSFWSYENREVEYVRDHPFEVGPRYSNLVYIGEGAYGMVVSAIDHLTKT KVAIKKISPFEHQTYCQRTLREIKILTRLRHENIINIQDIIRAPTVDEMKDVYIVQCLME TDLYKLLKTQKLSNDHVCYFTYQIMRGLKYIHSANVLHRDLKPSNLLVNTTCDLKICDFG LARVADPNHDHTGFLTEYVATRWYRAPEIMLSSKGYSKAIDVWSVGCILAELLSNKPIFP GKHYLDQLNHILGVLGSPSQEDLNSIINEKARGYLQSLPFKPKQPWNKLADPDALDLLDK LLTFNPHKRITVEEALAHRYLDQYYDPADEPVASEPFTFETELDDLPKEQLKKLIFEETN LLRQKQLSPPKTTPEWVKFCKQLFGGFSILLWIGAILCFFAYSIVATTSEDPSKDNLYLG IVLTAVVVVTGCFSYYQEAKSSRIMESFKNLVPQFAIVIRNGEKLNVHAEELVVGDIVEV KFGDRVPADIRILSAHGFKVDNSSLTGESEPQTRTPEFTNDNPLETRNIAFFSTNAVEGT CIGIVVSTGDRTVMGRIAGLASGLETGSTPIAREIAHFIHLITAVAVFLGVTFFIIAFIL GYNWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTI CSDKTGTLTQNRMTVAHMWFDDHIVEADTSDDQSNATYDKNSATWMALARIAMLCNRAEF KQGQDQFPVLKRECNGDASESALLKCVELSIGKVTQYRAAHPKICEIPFNSTNKYQASIH TENSHYLLVMKGAPERILERSQTILMNGVDEKMTEKWKDAFNQSYLELGGLGERVLGFCD LELPKSKFPKGYKFDADAENFPLTDLRFVGLMAMIDPPRAAVPDAVSKCRSAGIKVIMVT GDHPITAKAIAKGVGIISEGNETVEDIAVRKGIPVSQVNPREAKACVVHGTDLRDMTPAQ IDDVLKYHSEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIA GSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLFFIIAD VPLPLGTITILCIDLGTDMVPAISLAYEQAESDIMKRMPRDPINDKLVNSRLIGMAYGQI GMIQASAGFFTYFVIMAENGFWPKRLFGLRREWDSKSVTDIEDSYGQEWNYGQRKVLEFT CHTAFFMAIVIVQWTDLIICKTRRNSVIHQGMMNHHMTFGLFFETTLAAFLAYCPGLDKG LRMYPLKWTWWLVPLPFSIVIFIYDEIRRYILRRNPGGWLEMETYYSFKSLPKSQKAAYG VVGGALTLGTALQGEELHAPEYPWSHNGLLSSFDHASIRRGYQVYKQVCAACHSMNFMYY RNLVGAVLTEEEAVAEAESIDVQDGPNDEGNMFLRPGKLSDRFPNPYPNEEAAKVANNGV LPPDLSFITGARHGGEDHVFSILTGYCDPPAGVEVQEGLHYNAYFPGGWIGMARPLYDEI IEYDDGTPATTSQLAKDISTFLRWCAEPEHDERKRLGLKVIFISVMLIMFYFKRHKWMTL KSKKIAWIRPDQPSRCTYKLGVIKDSPHTHRPRRPKIFPNVLSQIGNTPLVRMNKIPADD GVQCEMLAKCEFFNAGGSIKDRIATRMVEEAEKSGRLKPGDTLIEPTSGNTGIGLALVAA VKGYRCIIVLPEKMSKEKVDVLKALGAEIIRTPTSASFDSPDSNMRVAARLLREIPNSHV LDQYRNPANPLAHYDETAEEIIQDCDGKLDMLVCAAGTGGTIAGLARKIKEKIPSCLIIG VDPVGSILAQPKDKTFYEVEGIGYDFLPTVFCRKYVDRWYKSEDKPSFIMARRLIRQEGL LCGGSSGSIMYCAVQAAKDYKLGPDKRVVVILPDSIRNYMTKHLNDDWMRARSFMSDNES N-EEQNNIGSYEGERNEKNERHGYGRAILPNGDTYEGSYKNGKRHNNGVYRFKNGARYTG NWKDNVKHGVGTFIYPDGTKYEGDWVDNLRWGNGKYSYLNGDYYEGEWKNHKRNGLGCYY FVESKSRYVGLWKDGQRDGHGEMIMEDCKYVGKYRSNKPYGEGKYIFEIRCKQIGFYVMP QIMDLITKDLSEPYSIYTYRYFIHNWPNLCFLAMYAKECVGAIVCKVDFHKKIFRRGYIA MLAVAKEHRHKGIGSHLVIRAIKGMVNDNCDEVVLETEITNHAALRLYENLGFVRDKRLF RYYLNGVDALRLKLWLKEISSIQFNLPAGQKKCLKEEIHKDVLVTGEYSITAVPEQKASL KVVDSKGHFLYNKEDAEKGKFAFTTEEFDMFEICFESHVPHGVHGLDREVSLTVKRGVEA KNYADIAKAEKLKPMELELKKLEDLSEAIVSDFARMKDREEEMRDTNESTHSRVLYFSLF SMSCLLGLATWQVLYLRRYFKSKKLIEEMESGRTSSVGNDILGFHGNVVNRPEHGSLDWV KICEKASKIITFIDLAGHERYLKTTVFGMTGHAPDFGMLMIGANAGIIGMTKEHLGLALA LCVPVFVVVTKIDMCPPNILQETLQMLHKVLKSPGCRKIPVLVQNQDDVVVSATNFTSER MCPIFQVSNVTGENLNLLKSFLNLLSTRMPNDPAEFQIDETFAVPGVGTVVSGTTLRGHI KLGDTLLLGPDPNGGFMSIVVKSIHRKRMPVKEVKGGQTASFALKKSQIRKGMVMVSPAL EPRACWEFEGEILVLHHPTTISVKYQAMVHVGSVRQTATILSMSREHLRTGDKAIVRFRF IKNPEYIRMDTRLVFREGRTKAVGTITKLFPYISANLRQSRPLKKSQQQEKLLLPENQKF YLFKVLKAHLLPLTNVAFNKSGSNFITGSYDRTCKVWDTDSGDNLAVLRGHTNVVYAIAY NNPFGDKIVTGSFDKTCRLWDAQTGKCYYTIKGHDAEVVCVSFNPQSCLATGSMDNHAKL WDLICHFKGHTQEIIAVSFNTVGSQLITGSFDHTVSVWDSRIHTLIGHKAEISNVQFNWD CSIIASGSMDKTVKLWDALSGQCMVTLLGHTDEVLDVSFDTTGQYLASASGDRVYNALTH SKLEGHENEISKVCFNPQGTRVMTASSDRTVRLWDAESGVCKQVLEGHTEEIFSCAYNYT GDIIITASKDNTCRIWKGDMFLEKHWKSVIHRSICDYFFEAQSKAAGPEDVPPILATPHH YLINIYKNQMYFIAVVLTEVPPLFVIEFLHRVVSTFEDYFGDCTESIVKDNYVIVYELLD EMLDNGFPLATESNVLKELIRPPNFLRTISDTVTGKSTNMSDTLPTGQLSNIPWRRTGVK YTNNEAYFDVIEEVDVIIDKSGSTVFAEIQGYIDCLIKLSGMPDLTLSFINPRLLDDVSF HPCIRFKRWESEKILSFVPPDGNFRLISYHIGSQNMVAIPIYIKHNICLKEGSAGRLDIT IGPKQTMGKTVENVVLEVPFSKSVLNATLTLTQGKYTFDPVSKVLIWDVGKIDPSKLPNI KGNIILQAGAPLPESNPTISVQFSISQMAVSGLKVNRLDMYGEKYKPFKGVKYVTKAGKF QVRTMATQLKSAPRFSTTDWFINNYNVSLGAEKERANASEVKQEARYLRNETNNRTKWDQ MDNNTRLADRVDDVRRWRDILDITLSNVEKEIVDLTTSKDELERALEDKNTPTEVNVENL VLRDARRGIDLVLDEADDELNKEKRVIEESKQLLQRQVDASFEIICALQEARQKLLADIQ DKNVAIDVDIEQYNLTEDSSMISFKPDPLRVPKGSVTLKEWEDHCRESRHRAEVALANAK MQREANVHAIQQTDNDLAAQLEATHFMLRKRIHEMEQALDELNWQKQQTEEEMKELEEDL KKQEAAIRATINPAKLAQTRMENRTFRPNMEKCLDSPFYGLSDEVRQIDSTKKALQEKFY QTQHAWNALEERLHNINKEIQSKTQALKLDKQCLNSRAKLLKNMDLTGLTNLKEELAVLI PEHREVVKKFVAEHGKFSLGEVTIDQLYGGMRGIKGLITETSVLDAEFGIRFRGYSIPDC QKMLPKAPGGIEPLPEGLFWLLCTGKMPSDAQAKAVSQEWANRAGLPSHVVTMLKNFPSN LHPMAQFSAAVTACNSESKFAKAYSQGIHRDKYWEYIYEDSMDLIAKLPTIAAIIYRNLY RDGTSVGAIDPNKDWSANFHSQLGYEDPQFADLLRLYLTIHSDHEGGNVSAHTCHLVGSA LSDPYLSFAAGLNGLAGPLHGLANQEVLVFLKGIQYTQEGLKEYVWSQLKAGQVVPGYGH AVLRVTDPRYTCQREFALKYLPNDPLFRLVSDLYKIVPDILLQLGKVKNPWPNVDAHSGV LLQHYGMKEMNYYTVLFGVSRALGCLASLIWSRALRFPIERPKSYSTALLQQMVQMPFVP PKVEKCETCGKSVYAAERQEAGGRIYHKLCFKCTVCKITLKLNNYSQADGVLYCKTDYQK NVLAKNAQIDVLFVHRDTPENSSKTPFQLTPENLKRVESILANYPKGFEPSAIIPMLDIC QRQHGWLPISAMNYVADYLKVSRMRIYEVATFYTMFKREPVGKYHVQVCTTTPCMVAGCG SGAILDAIKQKLGIDVGQTTADKTFTLGECECLGACVNGPMLMINDDYYEDLTAKDVNEI LDDIKAGKKPKPGPR--QSGRFSAEPSGGLTTLKEPPYGPGFKVLKELMQKYEKLEKIGE GTYGTVFKAKNRETQEIVALKRVRLDDDDEGVPSSALREICLLKELNHKNIVRLCDVLHS EKKLTLVFEYSDQDLKKYFDSCNGEIDPDTVKSFMYQLLKGLAFCHGRNVLHRDLKPQNL LINKNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIF AELANAGRPLFPGNDVDDQLKRIFKLLGTPTEDTWPGFTQLPEYKPYPLYPSSLQIVPKL NSKGRDLLLSLLVCNPSQRMGADDSMKHSYFSEMNANLKNDGQFIKYNGPVDCVHYPVQD VCDGWPLEYCEYHPAFEKAKEWVEKNLSEDVKELLIKRQTRGGKAQIKTKQKQDEKKITL SRSCRGKKKFVTVVSGLSTYEIDLKVASKAFGSRFACGSSVTGDDEIVIQGDIKDDLFDF LVEKWPQIDEDTIEDLGDQKRWYAVDRSSQYHQMRNDACYNRQQYNILWNGLPQLLNDIF VNTSAPGGLMGSTPQGYSKISIPSKETLIRDAGKLQVLDKLLTELKMNNHRVLIYSQMTR MIDLLEEFLWHRRHTYIRLDGSSKISERRDMVADFQSREDIFAFLLSTRAGGLGINLTAA DTVIFYDSDWNPTVDQQAMDRAHRLGQTKQVTVYRLICEGTIEERILQRALEKSEIQRMV ISGGNFAPDVLKPKEVVTLLLDDDDMDRQMSIEIVPNQLRHLRACLLCSLVKTLEQFEMD GCENCEKYLHMKNNRDHVYDYTSSSFDGLIAMMSPGDSWVAKWQRIDKYVKGVYAVSVSG KLPNNVISDLKSKGVHCRSRDTSMPRFVDALSKEKKEELSRIAKAIVAPGKGILAADEST ATIGKRFANIGLENNEDNRRKYRQLLFTSLHQYISGVIMFHESFYQKSDCGKPLPVLLKE QGIIPGIKVDTGVVNLAGTDNEVTTQGLDGLAERCAQYKKDGADFAKWRCVLKITSHTPS LLAMIENANVLARYASICQQAGIVPIVEPEVLPDGDHDLETAQRVTEQVLAFVYKALADH HIYLEGTLLKPNMVTAGQSCPTKYTPQQVAHATVLALRRTVPAAVPGVTFLSGGQSEVDA TVHLNAINCRPWALTFSYGRALQASVINAWKGKDDHITAGQQELLKRAKANSLASLGKYQ GEEGGAASQSLFVKDHAYYVASLPKVVKRRLKALKKLQVLTNLVEAKFFEELHKLECNYQ LKYEQIFLKRADIINARMEPTDEQCEWPNDEDDP--HVKIGDDETTKGIPDFWLTIFKNV DMLRAMVQPHDIPILKHLQDIKVHLD-GFTLDFLFEENEFFTNTVLTKTYYLKFNPQKDE ELLYEGPEVYKCTGTTIDWKPNKNVTVRLVKKVQKHKGRGTKRVLTKTVQNDSFFNFFNP PMVSENEMDEETDTLLEADFEIGQFIRERIVPRAILYYTGELVDEDEAGDDEDEDIILLK EGTDTSQGKPQLISNINACQAIVDAVRTTLGPRGMDKLIVDNHGKATISNDGATIMKLLD VIHPAAQTLVEIAKSQDAEVGDGTTSVVLLAGEFLKLSKSFVEEGVHPQIIIRAFRRASL LACQKIKDIAVHIKDDSKNHRQLLKRCASTALSSKLVAHQKDFFANMVVDAVMSLDELLS LDMIGIKKVTGGALEDSQLIEGVAFKKTFSYAGFEMQPKKYVKPKIALLNIELELKAEKD NAEVRVESVEEYQAVVDAEWSILYDKLEKLYMSGAKVVLSKLPIGDVATQYFADRDMFCA GRVTEEDLKRTMQACGGSIQSTVSSLTLGMCELFEERQVGGDRYNLFTGCPKARTCTLIL RGGAEQFIEETERSLHDAIMIVRRTIKNDAVVAGGGAIEMELSKYLRDYSRSVPGKEQLL INCMAKALEVIPRQLCDNAGFDATNVLNKLRQKHAGKWYGVDINSEGITDNFEACVWEPA VVKINALTAASEAACLILSVDETIKNPKSTVESGGQGMGGGRPFKGNNIIPNGHFHKDWK KHVRTWFNQPARKFRRWTKRNDKAKKIAPRPVAGLLRPVVRCPTFKYNSRIRAGRGFTIE ELKAAGFNKKYAKTIGIAVDFRRRNKSVEGFQVNVQRLKEYKANLILFPKKLNKPQKGDA TEEEMKLATQYKGKVLPIKASVVKEKARAITPEEKKYSAFVALRQARAHARLAGKRAKKQ KDAMPNIKIFCGTSHGELAHKICDRLGIELGKVTSKKFSNQETCVEIGESVRGEDVFIVQ SGCGEINDMIMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSPISAKLIANMLSTA GADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENIPEWRNSIIVSPDAGGAKRVT SIADKLNVDFALIHKERKKANEVASMVLVGDAKNKVAILVDDMADTCGTICKAAEKLFEA GALKVYAICTHGILSGQALTHINNSHFECVVVTNTIPQETNQNNCSKLQVIDISMILAEA IRRTHNGESISYLFGHVPLLTCRFYERKFPEIDDVVMVTVLSIAEMGAYVHLLEYNKIEG MILLSELSRRRIRSINKLIRVGRDECVVVIRVDKEKGYIDLSKRRVSPEEIIKCEEKFAK AKCVNSILTHVAQLMKYETDTQLEDLYMKTAWMFDRKMQRVGASYEAFKHAVTNPEVLDE CDIDPETKAVLLANIKRRLTPHAVKIRSDIEVACYEYEGVDAVKMALREGLKLSTEEMPI KINLIAPPLYVMTTQTLERAEGMARGQQKIQSQQKNAEKQAKLKSDQKKSAQAALVYSCS VCKAQMPDAKTYKQHFENKHPKSALPDELKDVMMEDLNKNMSMQGIQTAPHGNCAACSKL IVGQVITALRQLWHPEHFVCAHCKQELGTKNFFERDSLPYCEEDYHYLFSPKCAHCNEPI LNKCVTALDQTWHPEHFTCYSCGKPLGDEGFHERDGLIFCPSDYFNHFAPKCGACGQAIV ENFITALDQQWHPNCFACFECRRPFGASSFFEHEGLPYCEAHFHAKRGSLCAHCNQPITG RCITAMFRKFHPDHFVCTYCQKILNKGTFKEENDKPYCHQCYEKLFMRPLTDEETKILFE KLSKYIGDNIEVLINRSDGLYCFRYAKGRVHYVSDFIMKKAAHFPKENLVSFGTCFGKFS KNMKFRLHITALDYLAPYAKHKVWVKPAFEHRFLSGEHILKSGLGRMTDNTSKYQGVIVY SMSDLPLGFGATAKSTADCRHADVTNILVYHQADNGEYLRNEESLSEQRHFFVGGNWKMN GTYASIDEILKFLNGDDPKTEIVVAPPSLYLSYVRGKLISVAAQNAYKVEKGAFTGDISP TQIKDVGGDWVILGHSERRHVFKEPNELIGEKVGHALSAGLKLIPCIGEKLEEREANKTE EVCFCQMKANDWKRIVIAYEPVWAIGTGKVATPQQAQEAHHSVRQWISKNVSPDVAKCVR IIYGGSVTAGNCRELAQQPDVDGFLVGGASLKSEFVDIINARERQGLLDPAWERQQKKTF TAWCNSHLRKAGTQIENIEEDFQNGLKLMLLLEVISGEQLGKPDRGKMRIHKLSNVNKAL QFIESKGVHLVSIGAEEIVDGNLKMTLGMIWTIIVQNFHLSFKDGLAFCALIHRHRPELL DYGKLSKDNPLQNLNLAFDVAEKYLDIPKMLDADDMVSSAKPDERSVMTYVSAYYHAFAG AQKAETAANRICKVLKVNQENERLMEEYERLASDLLAWIRKTRPWLENRHTDNTIPGTRR KLAEFRDYSRAHKPPRVDQKAKLESTFNTLQTRLRLSNRPAYMPTEGKMVSDIATAWIGL ESAEKGFEDWLLKELQRLERLEHLARKFKQKCDIHEEWSLGKEDLLQAQDFKKCRLSDLK ALKQRHVAFESDLASHQERVEQIAAIAQELNQLGYHDVKSVNIRCQKICDQWDVMGSLSQ QRRNALDEAEHILEKIDRLQQEFARRAAPFSNWMDGTREDLIDMFIVHSIEEIQRLCDSH EQFKLTLGEAESEFNSIIGLVNEVNRIAQQYGITGAQDNPYSYITGNDLNKRWTSLKQLI PERDHTLQNELVKQQNNERLRRAFAQKANQVGQWIERYLDAVTSVALQKGKLEDHLNKLK NFEKEVYAYRSNIDELERYNNDIQEALIYDNKHTPYTMETLRIGWEQLLTLVNRSINEIE NQILTRDAKGITNQQLEEFRRSFLHFDKSRSRRLDSKDFKACLIALGYNIKDDRQGDADF HRILSIVDPNNFGFVTFEAFLDFMTREASDNESAEQVIQSFKVLSGDKNYITVEILRREL PIDQAEYCIRRMAPYRGRDGEPGALDYRSFSAALYGESDLNKLSIDKVDLKQKRILIRVD FNVPQKDGKITNNQRIVAALPTIKYALENGARSVVLMSHLGRPDGQKVDKFSLAPIADEL KKLLNKDVTFLHDCVGDEVEKACANPAPGSVILLENLRFHIEEEGKVTLKDGTKVKADPA KVEAFQASLSKLGDVYINDAFGTAHRAHSSMVGCKLPQRAAGFLLKKELEYFAKALEKPE KPFLAILGGAKVADKIQLIENLLDKVDEMIIGGGMAFTFLKVMHGTKIGKSLFDEEGSKI VGKLADKAKSKGVKIHLPVDFITGDKFAEDAAVGCACLESGINDDLLGMDVGPKTGDDFA EAILRARTIVWNGPPGVFEFKNFANGTKKVLDAVVEATKKGAITIIGGGDTATVCAKYNA EDKVSHVSTGGGASLELLEGKVLPGVAALSEAMSGIPPKSWQPPCVIVETSMGKMEVELY WKHAPRTCANFAELARRGYYNNVKFHRIIKDFMVQGGDPTATGRGGASIYGRSFEDEISA DLKHTGAGILSMANSGPDTNGSQFFITLAPTQWLDGKHTIFGRLSKGIQVLNRIGLVETD DNDKPLEDIKILRHRSRSRDRKRSRSRDKSRRAYKYWDVPPVGFEHVTPMQYKAMLASAM STNNALSRQARRLYIGNIPFGITEEMMMSHFNDQMKMAGVSQQDGEPVIACQVNMDKNFA FLEFRSAEECTQAMAFDGIIFQGQSLKIRRPRDYQPLPGLTENPSVGVVSTLVGDTPYKI FIACLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDQACLGLNGMQLG DKKLIVQRASIGKNPLAAMLTNLQIPGLNISDVSTEILCLMNMVTPEELEDEEEYDEILD DVREECSKYGSVKSLEIPRPIKGVEVPGVGKIFVEFHSVVDCENAQQNLAGRKFANRVVV TSYIDPDRYHRREFFIPLFDRVLVERFAAETKTKGGLFIPEKSQGKVLDATVVAVGEGNR TEKGDLIPVNVKVGDRVILPEYGGTKVILDEKEYFLFRNTDILGKLKRLKAQIPELKSSL NIISYLEHLKSTVESHYQLNDSLFSKAKIKPTNSVCLWLGANVMLEYDIDEARELLLKNT AVKTLSAVDDDLGFIRDQTTTIEVNMARVYNWDVKKRQKDKSMADESLSKAGLHFDDLNK LRILQPEVSSQSSELNEECKDFINKLSQFQSITSNFSKSLETIANAVNKKKFEAIGSRNK LKSVTKLKEAQQQQIKSLILERKMELERLKEQYRSLQKVEKEQLEMIERLTLNQKEHRRS REYYEKYRSRRRSRSPDELTPEERDARTIFCMQLSTKLRPIDLKDFFGKLGKIRDVRLIM DNRSRRSKGIAYIEFQDTESVAKALELSGQRLLGVPIIIQPSHGERNRSNGSVGPMKLYI GSLHYNITEEMLKGIFEPFGPIDELKLMRDHSTGRSLGYGFLQFKRGDDGKKALEQLNGF ELAGRPMKLGNVADYQLGSTLFDADEVDKAGFGMNATSRIQLMAKLAEGTGFEIPKAAAS VLNGGGDAPAPPIATQCFLLSNMFTANEKDAEWERELKDDVIEECNKHGGVLHIHVDKTS AQGHVYVKCPSIASAMSSVNALHGRFFAGKQITAAYVPLPNYHNLFPESIRAVQFILPSN KEEEREASPTPQAAPKKRSRRGAVSAEVYTEEDAASYVKKVVPKDYKTMAALSKAIARNV LFSHLDDAERSDIFDAMFSVNRHAGEIIIQQGDEGDNFYVIDHGEVDIYVNNDYISTIGE GGSFGELALIYGTPRAATVKAKSDCNLWGIDRDSYRRILMGSTIRKRKMYEEFLSKVSIL ENLDKWERLTVADALEPVQFEDGAVIVRQGDAGDDFFIIVEGAATVLQKRAENEEPVEVG QLGPSDYFGEIALLLDRPRAATVVAHGPLKCVKMDRSRFERVLGPCSDILKRNIAQYNSY VSLSVSSYKGLAKIYRLLHIAEYALTHVLTTCNTQMYQTIHRMLQEAVGSLVPPFDAVWL ESTNKKAAMKLEKLDIDLKNYKSNSIKESIRRGHDDLGDHYLECGDLCNALKCYSRARDY CTSSKNIVYMCFNVIKVSIYLQNWSHVTSYVNKAESTPYFCESKESNQQVVTKLKVSAGL ADLVLGRYKNAAKNFLQANFDQVDFPELLSSNNIATYGALCALATFDRQELQKLVISSST FKLFLELELQLRDIIYQFYDSKYALCLKLLDNIKDNLLLDMYLAKHVDNLYAQIRNRALC QYFSPYKSADMRKMAEAFNTTVSGLEDELTKLILDGKINARIDSHNKVLYAKDIDQRSLT FDKCFALEEEFQRKTKALILRAAVVKSQIQVKSPPRETNQASEISIMPGNATTMANINQL VNKAEDVMDQVLRHGKHILPHIARLFIIGTFIEDGFRMYVQWGEQRDFMNDTWGCGYYLA SFFVLYNLFGQLGGCVLILIRKFVEIACIDLFLIILLQSVAYSALWDLKFFLKNLALAGG IVLLWAESKSEGHSLFAGLPSAGVDRPKTYMQLGGRVLLVCMCLTLLRFEFVWLQVVQNV VAIALVFFIAVGYKTKLASMTLAVWLMVLNCWLNAWWMLPSTSYSRDFLKYDFFQTLSVV GGLLLVVALGPGGYSMDEHKKKWRKRVTLIPGDGVGPELMTSVKDVFSAIGVPVDFEEIY VSRNKVCLKGIIASPLMTLNMKIRKALDLFANVVHIKSMEGIKTRHNNLDIVIIRESIEG EYSALEHESVPGVIESLKIVTKTNSQRIARFAFDYAVQHGRKKVTAVHKANIMKLSDGLF LEQCTNIAKSYPTIKFESMIIDNTCMQLVSRPQQFDVMVMPNLYGNIVDNLAAGLVGGAG VVPGESHSTDIAVFEPGARHSFAESAGKNQANPTAILMCAANMLEHLGLDQYARIIKTAL CKVVASGKHRTNDVGGYTTKTDFTKAVIKNLSEDFQSFFSRATNIMERALEENCDLFTDY RGIEDGDRLTEGEQVKLNRNFSNERWSKNRTVTSLDWSDQYPELLLASYNNNESQPQEPD GVVLVWNIKYKKTSPEYVFHYQSPVTSACFAKFHPNLVIGGTYSGHIVLWDNRSNKRTPV QRTPISAAVHTHPVYCLDVVGSQNAHNLASISTDGKMCFWNLDMLSQPQETMELQHKQSK AAAMCFSFACCDSNNFVLGCEECVVYSACRHGNKTGILDIFEGHQGPVTGVDYHNNSGPI DFSSYFISSSFDWTVKLWNIREKAPVHSFEDNSEYIYDAKWSPIHPSIFSTVDGSGRLDL WNLNNDTEAPTTSTMGRAANKCSWHQSGLHIGIGDDEGGVHIYDVSESLAAPRSDDWSKF SHTLQELKQDQMEQSDDQLEKQVLAAAQILEQQVDSKLEELDNLSDSDFEELRKKRLLNL KKSQVQKEEWLKLGHGNYTEIHDEPEFFDVCKKSKNVVCHFYRPTTSHCQIVDKHLEILS SSHIECKFIKINAERCHFLVERLRIKVIPTICLIKETKSVDYIVGFDDLGGRTDFATSRL EWRIAQAGILNYAGDLLHPPTEV--KTIYSSKNEEDKAVTLTGFGGIRMVKVQQRPKPGP GEILIRVRAGGINFSDLMVRQGVIENPPKTPFIMGFECSGEVESLGEGVNGFSIGDRVIG ISKCWAESVCFVYKIPTGMSFEDAAAIFFNYVTAYILLFDIANLRPHQSVLVHSAGGGVG VAVSQLCRTVEGVVLFGTASNKHESIKNM-YDHLLDH-SVDYVQEVRKISPEGVDIVLDS LCGEDTNKGISLLKPLGKYVLYGSSNIVTGETKSFFSFAKSWWQMDKISPIRLHDENKTT SGFNLRHFLVLEKIFNLYNKGKIKPIIDSVWAYEDITEAMQKMHDRKNVGKLLLDPKMMS KKQTPSEFLKQIIGRPVVVKLNSGVDYRGVLACLDGYMNIALEQTEEYVSGQLKNKYGDA FIRGNNVLYISTQKRRIMSATQGALLLRRQLTELNKHPIEGFSAGLIDDNDIYKWEVLVI GPPDTFYEGGFFKAHLTFSADYPQKPPKMKFITEIWHPNIAKTGDVCISILHDPGEDKYG YERPEERWLPIHTVETIMVSVISMLTDPNDESPANLDAAKEWRDSKEEFRKKVANCVKKS QEMTVKSKLPAVQQTLVEYGKYMCDCLPRFIQHVQVVHGSELEVFIHPEGIIPVVTFLRD HTNAEFTSLADICGVDFPTRKNRFEIVYNFLSLRYNQRVRVRTYTDELTPVPSITPLFAG ANWYEREIWDMYGVYFQNHPDLRRILTDYGFEGHPFRKDFPLVGYVEVRYDDEAKRVVVE PIEMIQEWRNFDYTSPWESFPNFRENLNPFCQVDYRAKVWTCNFCFQRNSFPPQYSAISE QHQPAELVPHFSTLEYTLTRVQCHPPIFLIVLDTCMEDEDLQAVKESLQMSLSLLPPNAL VGLITFGKMVQIHELGCEGYSKSYVFKGTKDFTAKQVQELLGIGKGHMQLPYSRFLQPLH KCDMALTDLLGELQRDPWPVAQGKRPLRSTGVAASIAVGLLECTYPNTGARIMIFMGGAC TQGPGQVLGDELKYPIRSHHDIEKDNCKYMKKAMKHYESLAHRACNNGHVVDIYACALDQ TGLLEMKYLPTLTGGHMVMGDSFNTSLFKQTFQRVFAKDSKNEFKMAFAANIEVKTSKEL KVQGCIGSCTSMSNGTNISETEVGVGGTCQWRMCGLYPNTTYAFFFEVANQHNAPIPQGG RGYIQFITQYQHSSGQRRIRVTTLARNWFDAAVNIQNIAAGFDQDAAAVLMARIAAFRAE TDEGPDVLRWLDRMLIRLCQKFGEFNKDDPNSFVLSQQFTLYPQFMFHLRRSQFLQVFNN SPDETTYYRHMLMVEDIQQNLIMIQPIIYAYSFNGPPEPVLLDTSSILPDRILLMDTFFQ ILIYHGETIAQWRKAGYQDLPEYQNFKQLLQAPVDDAQDILQTRFPMPRYIDTESGGSQA RFLLSRVNPSQTHNNMYSEGGGHVLTDDVSLQVFMEHLKKLAVSSNSMANLTSEQQMKLL SDVEMEMMADMYNRMMNACQKKCVPPKYKESDLSKGEAVCLDRCVAKYLEVHERIGKKLT SLSIQDNENAQKMQSSSPSTIIHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYR KKVVVDGNEVQVDILDDYAAIRDNYFRSGEGFLCVFSITEQESFLQTADFREQILRVKND DNIPFLLVGNKMDLENKRQVSSQEAQAKAQQWKVSYVETSAKTKENVDKVFYDLMKLIRD KKNMNKLPKKKCIILKLYTGLREVVTDHLVNKVREEVLESLQNNFLQVLNAAWNDHQTSM VMIRDILMYMDRVYVQQNNVDNVYNLGLMIFRDQIIRYPPIHQHLRETLLSMVAKERKGE VVDRGAVKNGCQMLMVLGIDSRAVYEEDFERPFLVQSAEFYRLESEKFLSENSASVYIKK VEARILEEQERAVHYLDKSTKEPIVRVVQEELIRKHMRTIVEMPNSGVVHMLKNNKTEDL DCMFRLFSVVHDGLKTMSDCISAHLREQGKSLVTEDSNGCNPIIYIQSLLDLKDRFDHFL HESFSNDRLFKQMISSDFEHFINLNSKSPEYLSLFIDDRLRKGVKGMSEQEIETVLDKSM VLFRFLQEKDVFERYYKQHLAKRLLLNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFKD MTVSNTIMEEFRQHVNFRANMFGMDLCVRVLTTGFWPFQSSTTTCNIPATSRQAFETFRR FYLGKHSGRQLSLQAQHGSADLHAVFHASKRNGSMKSGGLRKHILQVSTYQMVVLMLFNS RDVWTYEEIKNETDIPERDLMRSVQSLALGKITQRVLTKDPKTKEIEPNHSFTVNDQFTS KLFRVKIQAVTNKSDSEPERVETRNKVDEDRKHEYPAAVVRIMKARKQLQHNVLVAEVTE QLKARFLPSPVVIKKRIEGLIEREYLSRTPEDRKVYTYVADRINVFPSRMAMTNMKTRLK GAQKGHSLLKKKSDALTHRFRQILKKIIDTKIMMGEVMKEAAFSLAEAKFAMGEFNHLVL QNVGRAKVKVRSKKDNVAGVMLPTFECDQDGPDSNVLLGLGRGGQQTDRLKKNYSKAIEL LVDLASLQTSFIVLDEAIKTTNRRVNAIEHVIIPRIELTLDYITTELDEREREEFYRMKK IQRKKAQIRNVMDMLHDDEDLLFPIRVVITGAAGQIAYSLLYPVAKGDVFGHDQPIVLVL LDIEVMLGVLKGVVMELVDCALPLLREIIPTADPNEAFEGADVAILVGAMPRKEGMERKD LLKANVKIFKVQGEALDKHAKKSVKVVVVGNPANTNAFICKKYAPSIAPENFTCLTRLDQ SRAQSQVASRQDVHNIIIWGNHSSTQFPDVSHGCVIMDAVKDEAWLKGAFISTVQKRGAE VIAARKLSSALSAAKAICDHLHDWWFGTPEGRWVSMGVPSDGYGVEKGLIFSFPVVINKT YSIVTGLELDAFAKEKICATQKELIEERDQALEACSGSGGVLMVGPNFRVGKKIGCGNFG ELRIGKNIYNNEHVAIKLEPMKSRAPQLHLEYRFYKQLGQTEGVPQVFYFGPCGKYNALV LELLGPSLEDLFDLCDRKFSLKTVLMLAIQLITRMEYVHSKHLIYRDVKPENFLIGRQTS KKRNIIHIIDFGLAKEYIDPDTHKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEAL GHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEELSKYLHYVRRLD FFETPDYDYLRKLFSDLVDRNGWICDWDFDWIARQIHLGGSVQVVSSTNGELQGTGGQSN IPINNTPDVEAAESVKCCMTTIRPFTCDDLFKFNNVNMDPLTETYGISFYLQYYVHSSEY FYSAESPSGDIMGYLMGKAEGSGENWHGHVTALTVAPEYRRLGVAAKLMNIMEEVSEQKK CYFVDLFVRVSNEVAIDMYKRLGYVVFRDVLNYYTGETDENAHDMRKALSRDVDKKSIIP FPRPVLPEELDQLLDSALDLMRRLPPQKIDKNLSDLIDLVPNLCEDLLSAVDQPLQIMRD KEVGKDFLLCDYNRDGDSYRSPWTNQYQPPIDDGAVPSERLRKLEIEANSAFDQYRDMYY EGGVSSVYLWDLDHGFAGVILIKKAGDGSNKIKGCWDSIHVVEVQEKSSGRAAHYKLTST AMLWLQTSKSGSGTMNLGGSLTRQAESDFNVGEASPHIANIGRMVEEMENKIRNTLNDIY FGKTKDIVNGLRSTQSAKKKMLQSELAGALNKRAQFDGDFDEMEVQ-DEIENQENIEIID STQKVDPEKRMTTPYMTKYERARVLGTRALQIAMCAPVMVELEGEIDPLAIAMKELKARK IPIIIRRYLPDGSYEDWAIDELIITDKGPTLKERLMAPAGDTAFTAGRGLLAGASLLGLG GLCYYGLGLSDQVGAIDRAALWPATVKERIRNTYAYFGGSLIFTALSRSPTFMNVMFRSS WMTLIGSMVAMMGTGILCQSLPYTESVKHLAWMLHSCVVGAVVAPIALMGGPLLVRAACY TVGVVGGLSALAMCAPSDKFLYMGGPLAMGLGVVFISSIGTWFLPPSTALGAGLYSIAVY GGLALFGAFLLYDTQKVVYRAEHHVAYADQPFDPINNSVGIFMDTINIFIRIAMILSGSS NRRKMEIMYVYSKRRSEFGRQCSFSDRPAELLCDIPVDPVLRSSFIDKNPVDVSIDCGPS YSEH-----------------EWGWPRDINPLEMEQVIRFRKKVEKEEGYLRSMADLSKR MEHCIKQNNAVDIYENFFED-----------PPYIDMFN-----KRSAVHITWYPDGPKK IAVAYRDDSFDEISEGGLYSFIWDVENSNHPDFTLKPPFPLCCLEFSPKDSHLLIGGLEN GQVALFDTRKNSRPCELTHIESCHRDRVTKILWIASKIGTECFSASVDGQVMWWDTRKLQ EPLEYMCLDTAKRQNLKTADGALSIEYEATMPTKFMAGTEQGNVLTCNRKAKSVQERVSS VHVGHVGGVRAIQRNPFFLKNFLTVGDWTAKIWVDDHKDSAIWSSKYGQHYMTDACWSPT RAGVFLTSRSDGMMEVWDITHMHANSVLKVKVTEECLDSMRMYDNGQMVAVGSREGLVML YNLNESLFLPDKNEKNIISNLFEREARREKLLESKHREFRTKERIKSSWDELVNRCQIIA NPLASRKLTKKIYKVIKKALRKGIKDVQKCLRKGEKGLIILAGDTHPIDVIAHLPIVCEE FQLPYCYVPSKEALGEASGSKRQTCAMLIKQHGDYKELYQECVDAVSSLPLPLMPVENFE EEGLAKNPNLELAQWKFLLQTDNYKNNSKIKNDLLQAVKDGNMAPFYEELCADLQWKLDT NLLEHMKSENEKKLKELDDSLEDAEKNQGEMEIRDIMLKKAEYYSSIGAKELALSQFRKV GEKTLTLGYRLDMEFHQIRIGLFYMDHDLIKRSFEKAQSLIDQGGDWDRRNRLKVYRGTY CMAVRDFKMAASLFLDTVATFTSYELMDYKTFVTYTVFCCMIALARPQQREKVIKGSEIL EVLHSLPDIQRYLFSLYNCQYKEFFKYLAIVEQILKHDRYLAPHYSFYAREMRIIAYTQL LESYRSLTLVYMARSFGVTVEFIDQELSRFIAAGRLHCKIDKVGGIVETNRPDSKNYQYQ ETIKKGDILLNRIQKLSRVINITRNLRSSSAPILGTPYTKLTIGVPKEIFPNERRVALAP ATVQTLKKGFTVKVEENCGLLASFNNADYEQAGAKIAVEEVFGSNLLLKVRAPTIAEANK LQAGNTLLSFLYPAQNKELIDLLVKKNVTAFAMDCVPRISRAQVFDALSSMANISGYKAV LLAANHFGRFFTGQITAAGKVPPAKVLVIGGGVAGLSAIGTAKNLGAIVRVFDTREAVRE QAKSMGAEFLEVSVKESGEGGGGYAKVMSKEFIEAEMALFAKQAKEVDIIITTALIPGKK APILITKQMIESMKPGSVVVDLAAEAGGNIETITPGQLTVHHGVTHIGYTDLPSRLPTQS STLYANNISKLLLSFGYYVDLKDDVIRGSIVSHQGQLLWPPPVEAPPNYFMNTLKESFMY TAGLGGILGLGCVSPNPAFTTMVTTFGLAGIVGYHTVWGVTPALHSPLMSVTNAISGITA VGGMILMGGGYYPTNTIEALAATAAFISCINIGGGFLVTQRMLDMFKRPEDPPEHKYLFL IPATAFIGGYGLATQGNYPDVHQMTYLAASLCCVGALSGLSSQKTARLGNVLGMIGVSSG LAATLGIMKPTNEVLTQMIACMGSGALIGTVMAKRMEVTDLPQMVALFHSLVGAAAVITC LANYMAEQPHFDTDPAANVTKTALFLGTYIGGVTFTGSLVAFGKLQGLLDSSPLLLPGRH PLNASLGLANVAAMGYFMMTNDNTGLYMLGATSSLSAVMGVTLTMAIGGADMPVVITVLN SYSGWALCAEGFMLNNNLMTVVGALIGSSGAILSYIMCKAMNRSLPNVILGGYGTSSYAG GQAMKIEGVHKEIKVNETVELINEANNILIVPGYGLCVAKAQYPIAELVQLLRSKGKNVK FGIHPVAGRMPGQLNVLLAEAGVPYDIVHEMDEVNPEINNIDLTLVIGANDTVNSAAEED PNSIIAGMPVIRVWLSKQVIVMKRTLGVGFAAVDNPVFFKNNTWMLLGDAKKTCDALLAS TKMDRPPAIPGVPPGLEYLSQIDQLLVHQQVEIMEMVTGWEACNKYQVKNTLGQQVYFAS EESDACARQCCGASRGFVMHISDNFGVEIVRVRREFNCCACYSCCANCKMEISIEAPVGQ VVGYATQNCLTPRYTISDAIFKLTGPKCICQGICCTQDVEFKISTDVIGKISKQWSGFGR EVYTDADNFSISFPLDLDAKMKATLLGTLFLIDFMYFEQKQNSADTELQEFLAVEQQKAM FQLHIHRLTNHCWDACVDQPKEKFSQRNETCLSNCVERFLDVSLLISTRFQQMLQKSLMN RSEGLVQRKNAAQEVEDLDSKEARLTLMEEVLLLGLKDKEGYTSFWNDCLSSGLRGCIIA ELALKGRIELEKTGMRRRSLLNRKIKCKSDVLTGDVLLDEALKHIKETNPPETTQSWIEY LSGETWNPMKLRYQLRNVRERLAKNLVEKGVCTTEKQNFVLFDMTTHPLNDKSIKSKLVK KVQDSVLSRWTNDVHRMDRRMLMLIYLSHVSDVLENAFAPLSDDDYEIAMKRVRYMLDLD PEQEAQREGTNELLWAIIAALSKAKKISEATEENCEVCVKHLTKFINSLDKVEEAFRKSC KKSKNDDNRFCYYVGGLEESATGMLGEMSKPISWSMPADKVCMKLYRKDAQICDLKYEKT FDFSKVNFKKLKVNELKQILLDWGEDCKGCTEKSDYINLVEQLLPKYAPDAAPSSILQGF KLNWMNLRDADSGKVLWQSTDDLSIPDIEHEARVPKKILKCRAVSREINFSSIEELTKFR LEQRVLFKDKCIEEWFFDFGFVIPCSTNTWQSIIEAAPEGQMIPASVLSGHVVIETKFFD DQILVSQSRVRIFYVMPKVVSRSVVCTDVKDQEEYQGEKPLNVYYCICGQMSLILDCPIE KLPLRKYDGARVIDSSKHAHKVTCDVDDVVHLRRETGIEKQFRFKCKKCSLWLFYRHKNQ ITFIVENSLVTQNDLKPDVYSRIAQPKKVMVTKHTKNMGKFSSVTVSTVDEEEDEIEAKE IADSYAANARVIEKQLLRKGVNKRKLLEQPDDDAKKARPKGTLIDLVKNSTKLSAAQQKM SYADMAFTFACPASVNVKQVDVPTLSGDFGILPQHVPLLAVLRPGVIAVHEADGAMKKYF VSSGSVTINDDSSVQILAEEACPIDHLDAQAIRDGATSAAQDLSSEQSKAEAQIALECYD ALQKAVECKFFATELKSRLDESARSKEIIETGHGLDRKKKFKYLTSELRLTEALHEPHIC EKILEYNVHAEREGSLRYAKGMSETMQTLHGLVNKGVKVELGIPYELWDKPSAEVSKMHR ACFTFAEEYEERIEEWYYNYQKNLLKYLCSDHYLKDKDQLFLKIKVTSENDVKNLFCIKS KFGKLNVAVNCAGISIAAVVYNQNKDRVHSYEDFIKVLTVNTGGTFNILRLSSQMMAKNE PNSNGERGVIINTASTAAFDGQKGQAAYSASKGAIVGMTLPLARDLSILGIRVVTIAPGL FNTLSLNSLPEKVQSFLANRIPFPSRFGSPDEYAHLVQFIIENHFINGEIIRIDGALRSR PFSFRVHGRNENAKQQLSRDYPVVDHEYDAVVVGAGGAGLRAAFGLANKGFKTACITKLF PTRSHTVAAQGGVNAALSNMESDRWEYHFYDTVKGSDWLGDQDAIQYMCEEAPKAVTELE NFGMPFSRLENGKIYQRAFGGQSLDFGKGGQAHRACCVADRTGHSMLHTLYGRSLKYDAD YFIEYFALDLIMENGQCKGVLALSLEDGNIHRFRCNNTVLATGGYGRCYFSCTGAHTCTG DGNAMANRAGIYNQDMEFIQFHPTGIYGAGCLITEGCRGEGGFLVNSKGERFMERYAPNA KDLASRDVVSRSMTIEIREGRGVGKDKDHIYLQLFHLPPEQLHARLPGISETAMIFAGVD VTREPVPVLPTVHYNMGGVPTNYLGQVVQSNGQDYIVPGLFACGEAASTSVHGANRLGAN SLLDLVVFGRACANTIETLNKPGDPAPRIDQNAGEATVANLDAIRHAKGTISTADLRLKM QKVMQEYAAVFRDGPTLKTGCEKLSALYKELNLKTTDRGMIWNSDLVESLELQNLMINSM LSAFTAENRKESRGAHAREDFPTRIDELDYSKPLEGQKKKTFAEHWRKHSLAHVDVATGK VSIDYRAVNDKVLDSSKVQTIPPKIRSYMGALSQEEIISNTRTVIQGLDSLRLEHHQLLN NLLSMNGIADKINNNIVEEKINMLKKAIEAIDLAIGEAQMMVSFAGHMETIESEKQKLRA QVRRLCQENSWLRDELSMTQQKLQHSEQKCAQLEEQKTHLEFMAAMKRYDSNAVLGFPEE DEENQATSQSSIVGGGYEVPARLRTLHNLVIQYASQGRYEVAVPLCRQALDDLEKTSGPD HPDVATMLNILALVYRDQGKYKDAANMLNDALQIREKSLGSDHPAVAATLNNLAVLYGKR GKYKEAEPLCKRALVIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEQYYQRALDIYQ SKVGPDDNNVDKTKNNLASAYLKQGKFKQKLSGKYDAGAEADVISWFKMLLGPGMKEMEK QLKDGQHLVKLAKEVRAKKMVLKANTLTAPFKQMENIQTFINFCSNYGVPKTGLFQTVDL YEGRNMPQVLNCLQQLGSEAQRHNMDGPTIGPKPTEKNIREFTEEQLKAGQLQAGTNKLA SQTMGGVRHVSDIKVDDMTREGHGVIGLQAGNKLASQAGMSFGAVRHVADIRADDMSKEG QGVIGLQAGSNKGASQTGMSMGSVRHVADIRADDLQKDGQAFIGLQAGTNKLASQAGMTF GGVRHAADIRADDMSDSHAVIGLQAGSNKGATQAGMKIGSVRHVADIRADDMEGQGVIGL QAGTNKLASQSGMTFGGVRHAADIRADDIAGQGVINLQYGTTDGANQSGMSFGSRRIIMP ESYSFGVDPISCHSWNKERNQIAILNSNEVEIHGFRWTLKETLTDHAQRITGIDWSPKSN QIVTCAADRNAHVWPALVVLGITRAATCVKWSPEGNKFAVGSGNRSVSVCYFDSMNDWWT NKKIKKPIRSTITCLDWHKNNQLLACGSTDFKARVYSASMKEVNESPSPTSWGSKLTFAN LLAEFPTEGGWIHGISFSGSGDKLAWVGHDSSICVADSIVKTEYLPFVDITWTSETALVV AGYDCVPLSYTYNNGAITFKAKIDAKKGGAMAHFRTQDTRGTTLNSIHQNTITQISIHSG TKDKCAKFSTTAADGQLVIWDCKKEPDTYVGFANLPNQVYRKSVKKGFEFTLMLVGESGL GKSTLINSMFLTDIYNNEHPGPSKRPNKTLKVEKMNVLLKEGGVQLKLTIVDTPGFGDAV NNSNCWQPVVEYIDSQYNAFLNAESRVIRQVSEDTRVHCCLYFISPNGHGLRQLDIEFMK QLHEKVNIIPLIAKADSMTAEECKTFKKTIMNEIMQNKIKIYEFDDEEERRIMKKMKERI PFAVVGSNMVVECNGRKIRARTYPWGVVEVENLEHNDFTALRNMLIRTHLHDLKDVTNNV HYENFRYEHLLASVKSPMLQIEEEKMEHAEKLKKMEMEMEMVFEAKVKEKQNKIKESDAD VGKRRDQMLKSLKQEEMELEEMREAFVRERDAWEEQYRMSRRYDSRTTIFSPEGRLYQVE YAMEAIGHAGTCLGILASDGIIIAAEKRNTNKLLDDVAFSEKIYKLHDDMACSVAGITSD ANVLINQLRIMSQRHQLQYHEPIPCEQLVASICDIKQAYTQFGGKRPFGVSILYMGWDHQ YGFQLYQSDPSGNYGGWRASCIGNNSSVAISMLKQDYKDGETNLNQALDLCIKVLVKTLD TNKLTADKVEIATLTRSNDKTRIRILKCSELEQLIKKYEAEEAKNEKEKKKELNEAWEKL KNLASKREKSLFGAHEIQNFNRDAEETIAWMIEKDTLLSSDDYGRDLPSVQALQRKHETL ERDLGALCEKVKNLESESNRLSEIHPDQVEDITKKQQDILNCWQNLIEKASNRKNNLESS FYLHRFLSDYRDLISWISDTKAIITVDELAKDVAGAEALLEKHQEHKGEIDAREDSFRLT AEAGQKLLDSNHPAVQEVKEKLVTLANEKTSLLELWENKRILYEQCMDLQLFYRDTEQAD AWMTKQEAFLANEDLGDSLDSVEALIKKHDDFEKSLAAQEEKIKALDEFACKLIENNHYA ADDVKIRRDALLNRRNLLNAKAKSRRHVLEESYKNQMFERDYDETKIWIHEKLKAASDEG YLDPTNLQGKLQKHENFASELQANQARIETVTKSGEDLISQNHYNKDHIKERLGEIIMLW QKLVDQSDRKGSKLKEANDQQQFNRNVEDVEIWLGEIEGQLTSEDFGKDLTSVQNLQKKH SLLEADVAARQDRIDSITQAADQFVQTGHFDADNIKAKQLHLIERYRALHEPMQLRKLKL RDALRLQQFFRDIEDEEDWIREKEPIAASTNRGRDLIGVQNLIKKHQALLAEISGHDSRI TSVCSQGENMVKEGHFAADDIIRKVKELRDKWEILKNKASKRKEDLDDSLQAQQYFADAN EADSWMREKEPIVGNTDYGKDEDSAEALLKKHEALMSDLDAYGTVVEQLKEQAQQCKQQE APVIDDIGKECVVALYDYQEKSPREVSMKKGDILTLLNSANKDWWKVEVNDRQGFVPAAY VKKIDSNLTASQSNLADEYTISVRQGQIENQYKNLLDLGNQRKEKLDESCKAYQLVREAG ELAQWIADKETVVKTDEDIVDLEQVEGKQRKFDDFRKDLKANEARLEELKTVAQRLTAMG QTEAAEKIRIQIDDLNQRWAALEQVTQEKAQTLGSAYEVQRFHRDADETKDWIEEKENTL KSPEFGNDLATVQRLQRKHEGLERDLAAINEKVKDLDSTAARLMQTHPDQAQTIFDHQAE ILDKWNSLVKNSDSRKAKLLDSYDLQRFLSDFRDLMSWIKSMTTLVSSDELAKDVTGAEA LLERHKEHKMEIDARNGTFQAFELFGNQLLQKNHYAATEVKNKLDELRVARGNLEKAWIE RRAKLDQCYELQLFNRDCEQAETWMAAREASLEDSGDGTDSVEALLKKHEDFDRAISSQE EKIANLQQYADQLVRDGHYDTAGIENRRDEVLERWKKLKEALLENRAKLGEAQSLQQFSR DVDEMEIWINEKLQTAMDESYKDPSNIQAKHQKHQAFESELAANTDRIQAVLKMGEKLIE KDQCAGSEDAVRERVHKLLGDWQFLTGKSGEKGDKLKEANRQRMYTAAVKDLEFWLGEVE HMLEAEDYGKDLATVQNLVQKHKLLEADIQTHDDRVKDLNDQADAFIDTGMWDTENIKEK KQSINERYERVRTLAAHRRTRLNEAQTLHQFFRDIDDEEAWIKEKKLLVGSDDYGRDLTG VQNLRKKHKRLEAELSSHDPSIQSVQDTGEKLMADSSLMTSDIQQRVNQLGANWDELKEL AKNRGKKLDESLAYQQFGASIEEEEAWINEKQHLLSGDDYGDSLAAVQGLLKKHNAFETD FKVHEDRCNEITKEGGKLISEGNHNADNIKQRCQTLKAKLESLQGAANDRKTNLVDNFAF LQFIWKTDVVESWIADKEAQVRSEDYGRDLSSVQTLLTKQETFDAGLQAFEKEGIQTITS LKDQLISSKHSQTPAIEKRYNDVISRWQRLLQDSDARKQRLLRLQEQYRQVEDLYLTFAK KASAFNSWFENAEEDLTDPVRCNSVEEIKALREAQDQFKASLSTAESDFNQLAQLDKQIK SFNVGPNPYTWFTMEALEDTWRNLQKIIQERDMELANEQHRQEDNDALRKQFAVAANAFH QWLTDTRAAMTEGSGTLEQQLEATKRKSAEVRAQRSLLKRIEELSASLEQRLILDNRYTE HSTVGLAQQWDQLDQLGMRMQHNLEQQIQACNQSGVTEDALREFSMMFKHFDKDKTGRLN HQEFKSCLRALGNDLPMVEEGQRDPEFEAILDLVDPNRDGFVSLQEYMAFMISRETENVQ SAHEVEAAFRALTTGDKPYITSNELFANLTKEQAEFCRSRMKPYKDSTGRQIPDTYDYIS FTKDLFINSLQCYQCDSNEDNSCPTYKPFDLNINALVDCQSFETRIPGTFCLKITRQSPG WYGWIKQTRRCGSRSETGVAWGCKWSYEEDGVWKEMCYCDDRDGCNHASPIDKEDEENPQ LMSEYVKDIYCYMRILESREVNGKMRAILVDWLVQVHLRFHLLQETLFLSVAILDRYLQQ QVAKSKLQLVGVTSMWIASKYEEMYAPEVADFVYITDNAYTKSELRQMECTIMKSLDFQL GRPLPIHFLRRFSKAGEVEGETHNLAKYFMEMILVEYDMVHYPPSKIAAAALLLSKLTIE WTASLVHYSTYTEADLLPLVYKLASIVIKKLVAVKNKYASSKFLRISKSEKLSSQIVTSL ASKSRSRGRRHNNPSPGPDSELERIFIWDLDETIIIFHSLLTGTYAQKYGKDPPTSVSLG LRMEEIIFSLADNNLFFTDLEECDQVHIDDVSSDDNGQDLSNYNFMTDGFHAAATNNLCL ATGVRGGVDWMRKLAFRYRRIKELYSAYRNNVGGLLGAQKRELWLQLRSEIEVLTDNWLT LALKSLSVINSRSTCVNVLVTTTQLVPALAKVLLYGLSPVFNIENIYSATKIGKESCFER IASRFGRKCTYVVVGDGRDEEAAAKQMTWPFWRTTNHSDLAALHHALDLGYLMSALCVAG DRTTGQSVRTQNVMAACSIANIVKTSLGPVGLDKMLVDDVGDVTITNDGATILKLLEVEH PAAKVLVELAQLQDEEVGDGTTSVVIIAAELLKNADELVKYKIHPTSIISGYRLACKEAC KYIQDNLTISTDELGKQSIINAAKTSMSSKVIGSDDEFFANLAVDAAHAVKVSDGKGGFK YPIKAINVLKAHGMRAVESVLVNGYALNCTVAAQAMPKRITNAKIALLDFSLQKAKMKLG VQVLVNDPSKLEAIRQRESDITKERVQKILSTGVNVVLTTGGIDDLCTKYFVDAGAMAVR RCKKVDLKRIAKATGGQLISTLANMEGEESYDASMMGQADEVIQERVSDDELILIKGPKA HTSASIILRGANDFLLDEMERSLHDALCVIKRVLESKSVVPGGGAVEAAVSIYLENFASS LSSREQLAIAEFANSLLVIPKQLAVNAALDSTDLVAKLRAFHNSSQTKPEHKELRWIGLD LIEGKVRDNKEAGVFEPTISKIKSLKFATEAAITILRIDDMIKLAPEQPKGKSYGDACNA GELDEENAKLLVAKSVLNNILVEDKELTVQYDVYNVGTSAAYEVKLEEKSFQSTDFEVLH GSLVAQWNRIGPGTNVTHVIVLKPLKSGYFNFSAAEISYLPSENEPQTGYTSSLGEGYFM NYKDYDRRFSAHVLDWSAFVIMTLPSLAIPYLLWHQSKNKYEHGKSKKNGNVSQKEKTEK YRQILEVVKNLKGFIDAISNENVSLVISRQILSEFCNQLNNLPDEISKEIAHYTLDKVQP RVVSFEEQTGLIRQKLAALYEKEQNWKEAAKILVGIPLETAQKQYSNDYKLETYLKVARL YLEDEDPVQAEAYINRASILQAESTSEALQIHYKACYARVLDYRRKFIEAAQRYNELSFK NCVAEDEKMTALKNALICTILASAGQQRSRMLATLFKDERCQQLPAFNILEKMYLDRIIR NSELDEFSSLLQAHQKAVTADGTTILERAVIEHSMLSASKLYNNISFQELGTLLEIPSKK AEKIASQMISEGRMNGYIDQIDSFVHFEVHDALPCWDKQIQSLCVQVNEVVEKIRTLDPD WMAKHEESMMSMKLTEQVVRNFVVAKIFRENSDRINSMDFSTTGETLISSSDDDSIIIYD CQNGTPKRTLNSKKYGVDLIRYTHATNTAIHSSTKVDDTIRYLSLHDNKYIRYFQGHSKK VVTLCMSPIDDTFLSGSLDKSIRLWDLRSPSCQGLMNLPGRPVAAFDPEGLIFAAGIASE SLKLYDLRSFDKGPFATFRMQQDKDCDWTGMKFSPDGKLILISTNGQVIRLIDAFQGTPI QTYTGQLNNKGLPLEASFSPDSQFVFSGSTDGKIHCWNTETGTKVVVLNSEHKLPVQCVQ FNPKFMMMASACSNMAFWLPQVDEKHLIVEFKGDKSNIGLIRLNRPKVLNALCDDLMNEV NSVLDRFEKDPSVNCVILTGSDKVFAAGADIKEMKNLDFKQVYKGSFLSHWSRIAKFKKP IIAAVNGFALGGGCELAMMCDIIYAGSKAQFGQPEIILGTIPGAGGTQRLTKTIGKYKTM ELVLSGRRMSAQDAEKAGLVCKVFPPEELLNEAIKLAETIASLSPMVVQMAKESINASLE LSLNEGLHFEKLLFHQTFATEDRKEGMAAFVEKRPPKFTD >Hirudo_medicinalis XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXIMTLSNLMHTSVARRXIDQAAKYIGAGAATV GVAGSGAGIGSVFGSLVIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLILFAFM AAVKETGKVPEPTIHRIRITLTSANVKSLEKVSNDLIRGAKEKQLRVKGPIRMPTKVLRI TTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVQADVTIAD----- ----PAKTFAKDSIRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNII VMAAQISKKRKFVADGVFKAELNEFFTRELAEDGYSGVEVRVTPSRTEIIILATKTQNVL GEKGRRIRELTSVVQKRFNFQEGAVELYAEKVATRGLCAIAQAESLRYKLVGGLAVRRAC YGVLKYIMESGAKGCEVIVSGKLRGQRAKSMKFVDGLMIHSGDPMNEYVDQAVRHVLLKQ GVLGIKVKIMLPWDPNGKLGPKRPLPDNVTILDPKDQPAPEQPYSEQKGAKXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXRKQKQAKVTLGPQVAEGELVFGVAHIFASFNDTFVHVTDPSGVETIVRVT GGMKVKADRDESSPYAAMLAAQDVAERCKQIGINALHIKLRATGGNRTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRLMGKPRGLRTARKLRNHRREQRWADKD YKKSHLGTRWKSNPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP RDGCLNFIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVASVSLLALYKGKKERPRSXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-PRV KLVQSKTYSTPRRPYEKERLDQELKLIGEFGLRNKREVWRVKYTLTKIRTAARELLTLDE KDPRRLFEGNALLRRLVRIGVLDTSKMKLDYVLGLKLEDFLERRLQTQVFKLGLAKSIHH ARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLKSPYGGGRAGRVKRKNERKAEGGE AAMGNIFAKLFQGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVGEAREELMRMLAEDELRD AVLLVFANKQDLPNAMNAAEITDKLGLHSLRQRNWYIQATCATSGDGLYEGLDWLSNQLK NQRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------------------- ------------------------------NLNGRINKCGVISPRYDIEVKNLEHWTSYL MPSRQFGFLVMTTSSGIMDHEEARRKHLGGKVLGFFFMGRMHAPGKGISQSSLPYRRTVP TWLKTTSEDVKEQIYKLAKKGLTPSKIGVILRDSHGVAQTRFVTSNKILRILKAKALGPE IPEDLYFLIKKAVSIRRHLEKNRKDKDAKFRLILVESRIHRLARYYKTKKVLPPTWKYES STASTLVSVVEAREAKLFGKWSADDVVISDISLTDYIAVKDKHAKYLPHSAGRYQVKRFR KAQCPIVERLTNSLMMHGRNNGKKLMAMRIVKHAFEIIHLLTGENPLQVVVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREASFRNIRSIAECLADELINAGK GSSNSYAIKKKDELERVAKSNRMTEQMTLRGTLQGHDGWVTQIATTPQYPDMILSASRDK KLICWRLTRDVRYGYPQRALHGHGHFVSDVVLSSDGQFALSGSWDHTLRLWDLSTGQTTR RFVGHTKDVLSVAFSADNRQIVSGSRDGTIKLWNTLGVCKYTIEDCHAGWTTCVRFSPNT QNPLIVSCGWDKIVKVWNLTNCKIKTNHYGHKGTLNTVTVSPDGSLCASGGKDSQAMLWD LNEAKHLYTLDGGDVINALCFSPNRYWLCAATGPSIKIWDLEGKVVVDELKPEVMNTN-K APECLSLAWSADGQTLFAGYTDNLIRVWQVSITARMREYKLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKVVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTFNDLQDLREQILRVKDMDEVPLILVGNKCDLEDERAVGKLARQWNCTFLETSAKSK INVNEIFHDLVRQINKKNPDVMAEEKK-ADEHINLKVTGQDGSVVHFKIKKNTPLRKLMS AYCERTGVKMGSMRFRFDGQPINETDTPAQLDMEDGDAIDVFQQQTGGXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXMSDAECEDSPVAQGASGNMDLNTAIQEVLKTALIHNGVARGAREC AKALDSRQSLLCILANDCNEANYIRLVEALCAEHGINLIKVDDKKKLGEWAGLCKIDKDG KPRKVVKCSCVVIKDFGKESPALDVLNDYLKSRKMAAVRKKLVIVGDGACGKTCLLIVFS KDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSI DSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEATRRELMKMKQEPVRPEEGKA MAEKINAYAYLECSAKSKDGVRDVFETATRAALATRKKKSVKXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMYSTNAKIVKPEGDKPDESESAISQ ALLELEMNSDMKAQLRELVFTGAKEVDVGNRKAIIVSVPVPQLRSYQKVQTRLVRELEKK FSGKHVVFIAQRRILPKPTRKTRQKNKQKRPRSRTLTAVHDAMLEDICFPSEIVGKRIRH KLDGSQIIKVHLDKLNHLNVEHKLDTFAAVYKRLTGKEVQFEFPEYVLGRGGFRGGFGGR GRGRGRGRGRAKEGDKEWVPVTKLGRLVKEMKIKTIEEIYLFSLPIKEFEIIDYFLGGSL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDYNGHVGLGVKCSKEVATAIRGAIILAKLSI VPVRRGYWGNKIGKPHTVPCKVTGSCGSVEVRLIPAPRGTGIVSAPVPKKLLHMAGIDDC YTSATGQTATLGNFAMATYEAIANTYSYLTPDLWKETVFVKSPYQEHTDFLSRMSGGLDI LAPREEDVIKFLACATHVGTANLDFQMKQYVFKRKPDGVHIIDLRKTWEKILVAARAIAA IENPADVCVISSRPVGQRAVLKFAYYTGATPIAGRFTPGTFTNQIQAAYREPRLLVVTDP REDHQPVTEASYVNIPVVALSCTDSPMRYIDVAIPCNNKSNLCVGLMWWMLAREVLRLRG TISREVPWSVMVDLFFYRSPEETEKEFTTTEWGSETV--AQPV-ADDWAATDTGDWASSA ATNEWGGMKFNKLVSGSRRKNRKRHFNAPSHVRRVIMSAPLSKELRQKYNVRSIPIRKDD EVQVVRGHYKSPQVGKVVQVYRKKYVVHIERIQREKVNGSAVNVGIHPSKVVIVKLKMDK DRKAILERKAKSKQQGKHTEESVAPASSTSVGGSVRQRKAPASGAGGAGMWRFYTEDSPG IKIGPVPVLAISLLFIASVFMLHIWGKYTRG---GKKKSVANEVVTREYTVNVHKRIHGI GFKKRAPRAIKEIKKFAQKHMGTVDVRIETNLNKHIWSKGIRNVPFRVRVRLSRKRNEDE DSPHKLYTLVTYVPCANFKGLNTVNVESSSKSEFLVNGKYRLVRKIGSGSFGDIYLGINI ANGEELAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWFGEKEYNVLVMDLLGPSLE DLFNFCGRRFSMKTVLMLADQMIGRIEYVHNKNFIHRDIKPDNFLMGIGRHCNKVFLIDY GLAKKYRDNHTRQHIPYRE----------------------------------------- ---------------------------------FPAEFAMYLNYCRGLRFEEAPDYMYLR QLFRILFRTLSHQYDYVFDWTILKQKNATSMNAEKLKQRIGGKGSARRKKKVVHKSNLTD DKKIQLVLKKIGVNTIPGIEEVNMIKDDGDVIHFNNPKVQASLQSNTFAITGHSEIKSVT ELLPSILSQLRPDSLTALKKMAS----LE-EDDEVPDLVENFDEASKTEMTRYSLNPENA AKSAKARGSHLRVHFKNTRETAQNIKHMHLRRAVAYLKNVVNHKECVPFRRFTGGVGRCA QAKAWGTTQGRWPKKSAEFLLQLLKNAESNAEFKGLDTDHLMIEHIQVNRAPKMRRRTYR AHGRINAYMSSPCHIEVVLAEKEEAIEKP-KKKVSQKKLKKQKLLMRDKKGGPKLELTEE QKQEIKEAFDLFDVDGSGTIDTKEIKVAMRALGFEPKKEEIKKMIADIDKESSGTIDFDD FLTMMTSKMNEKDSKEEIMKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQEADRD GDGEINESEFLRIMKKTSLYMGISRDKWHKRRKTGGRQVQIRKKRKFELGRPSGNTKIGP RRIHTIRVRGGNKKYRAMRLDAGNFAWGSEAITRKTRILDVVYNASNNELVRTKTLVKNC IIQIDAAPFRNWYEAHYALPLGRKKGVKLTAEEEAVLNKRSKKTERKYEARKKTAKIETA LEEQFASGKLLACVASRPGKCGRCDGYILEGRELEFYQRKLKAKKGK------EKFQHIL RVMNTNIDGKRKVPFALTAIKGVGRRYAHVVCRKANVDVTKRAGELSEEEVEKVITIMSY PRQYKIPDWFLNRQKDIKDGKYSLVMANILDSKIREDLERLKKIKSHRGMRHFWGLRVRG QHTKTTGRRGRTVGVSKKKESVTDSEGEDSTPELDDIAQAAGLNEEPVSKAKQSRSEKKA RKAMSKFGLKPVPGVSRVTVRKSKSILFVINRPDVYKSPVSDTFILFGEAKIEDLSQQAQ IAAAEKLKADEEVDEFGIEAKDIELVASQAGVTRAKAIKALKNNQNDIVNAIMMGRVRTK TVKKASRVIIEKYYPKLTLDFHTNKRLCEEVAIISTKRLRNMIAGFVTHLMKRIQKGPVR GISIKLQEEERERRDNYVPEKSAVDEVDSATQELLTEMGFAENSKIQVVS-----MRWEY KEENPFEKRKLEGEKIRKKYPDRVPVIVEKAPKAKVGDLDKKKYLVPSDLTVGQFYFLIR KRVHLRPEDALFFFVNNVIPPTSTTMGTLYQEHHEEDYFLYIAYSDESVYGMRELRISKL CLNICVGESGDKLTRAAKVLEQLTGQTPVYSKARFTVRSFGIRRNEKIAVHCTVRGNKAE ELLEKGLKVKEYELRKCNFSESGNFGFGIQEHIDLGIKYDPSIGIYGMDFYVVLGRPGFN VSKRRRAIGKVGPKHKVTKEEAVKWFQQKYDGIILPGK---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GSGISLFIATNICETIVWKAFSPTTVN TGRGTEFEGAVIALFHLLATRQDKVRGLREAFYRQNLPNLMNLIATVFVFGVVIYFQGFR VDLPIKSSRYRGQYSSYPIKLFYTSNIPIILQSALVSNLYIISQMLSAKFSGNFIINLLG VWGDVGGGGPARSYPIGGLCYYLSPPETLQHMLEDPLHAVLYIAFMLGSCAFFSKTWIDV SGSSAKDVAKQLKEQQMIMRGHREASMIHELNRYIPTAAAFGGLCIGALSVMADFLGAIG SGTGILLAVIIIYQYFEIFVKEQSE--GMGSLFFQVERAFQKQPTVFLNRKKATGPRYYK NVGLGFKAPREAIEGHYIDKKCPFTGNISIRGRILTGVVLKMKMQRTIVIRRDYLHFIRK YQRFEKRHKNLSVHLSPCFRDVQIGDIVTVGECRPLSKTVTFNVIKVAKGTGSKKAFQKM MVNVPKTRKTYCKGQKCRKHTAHKVTQYKKGKDSLFAQGKRRYDRKQSGYGGQTKPIFHK KAKTTKKIVLKMECTECKYKKQLAIKRCKKFELGGDKKKKGQMIQF-GRVIRTQRKGAAG XFKAHNKHRKGPAQLKAVDYAERHGYIKGVVRDIIHDPGRGAPLAKVVFRDPYRYRQKTE TFIAAEGMHTGQFLYCGRKAELNVGNILPVGSMPEGTSICCLEEKAGDRGRLARTSGNYA TIISHNPETKRTRVKLPSGTKKLIPSSNRAMIGIVAGGGRIEKPMLKAGRAYHKYKAKRN CWPRVRGVAMNPVEHPHGGGNHQHIGKPSTVARTKSAGRKVGLIAARRTGRLRGTKQLPT KXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRRPARCYRYCKNKPYPKSRFCRGVPDA KIKIFDLGRKKAKVDEFPLCIHLVSDEWEQISSEALEAGRICANKYLVKHCGKDAFHMRV RPHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVNIGQIIMSVRAKDGHKEKVV EALRRAKFKYPGRQKINVSKKWGFTKWDREQYEVMRADGRLVPDGVNVQYKPPHGPLAAW KHAQKVTKVFGRTGSQGQCTQVRVEFIDETNRSIIRNVKGPVREGDILTFLESEREARRL RMTKGTSSFGKRHNKTHTLCRRCGGRCYHIQKKSCARCGYPEARMRKYNWSEKACRRRTQ GIGRMRHLKKVFRRFRNGFREGTVPKKVKA------------------------------ ------------------------------------------------------------ -------VTLLVALKVRFKDRITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDGQIFCLHGGLSPSIDTLDNIRALDRIQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHSNGLTLVSRAHQLVMEGYNWSHDKNVVTVFSAPNYCYRC GNQAALFELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFLMGAYKYLDELYRKKQSDVLR FLLRIRCWMLRQLKGVHRAPRPTRPERARRLGYKAKQGFIIYRVRIRRGGRKRPAPKGQV YGKPKSVGINQLKNQRSLQAVAEERVGRRCKALRVLNSYWIGQDSTYKFFEVICVDPFHK AIRRDPEIQWICKPVAKHREMRGLTSANRKSRGLGKGHGYSKTIGGSRKANWKRINRIEM HRKRGIAIGRLSEERKAWRKDHPFGFVARPTKAQDGSLNLMNWECGIPGKKGTPWEGGLY KLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSLLDEEKDWRPAVTIKQILLGIQE LLNEPNVKDPAQAEAYTIYCQNRAEYERRVREQALRFRDPSLGKSSKMLQHINYRMRCTL QDGRVFIGTFKAFDKHMNVILGDCDEFRKIKPK-NKSKEEKRTLGLVLLRGESLVSMTVD GPPPPEEGLARVPIPGAVGGPGVGRAAGRGIPT-LGLGGPARGVGMPPTQIMQPQPGMMR GAPPDDIPSFKLVLVGDGGTGKTTFVKRHLTGEFEKKYIATLGVEVHPLVFHTNRGPIRF NVWDTAGQEKFGGLRDGYYIQGQCAIVMFDVTARITYKNVPNWHRDLVRVCENIPIVLCG NKVDVKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLTGDQNLEFVAMPA LAPPEIEMDPSMVNKYEEELKIAQSTALPDDEDDINEGLKQYYQSKIEELELIVADKTQN LRRLEAQRNELNAKVRLVREELQLLQESGSYVGEVVKAMDKKKVLVKVHPEGKFVVDVDK NIDISDITPNCRVALRSDSYTLHKILPNKVDPLVSLMMVEKVPDSTYENVGGLDTQIKEI KEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ KFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSARLEGGSGGDSEVQRTMLELLNQLD GFEPKQNIKVIMATNRIDILDSALLRPGRIDRKIEFPAPNEDARLDILRIHSRKMNLTRG INLKNIAEMMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFELAVAKVMQKDSEKNMSM KKLWKLSFYENFLLSGSAAIISKTAAAPIERVKLLVQNQGEMIKMGRLDRPYNGVFDCTA RTFKNEGILPFWRGNLANCIRYFPTQALNFAFKDKIKALFVMNKSDPYMVNFSKNIASGG VAGAMSLVFVYSLDYCRTRLANDAKAGKKRQFTGMYDVYAKTIKSDGFVGLYRGFVISCV GIVVYRGCYFGFYDTLKPIVLGDDPGLFISFALGYVVTITSGLISYPIDTIRRRMMMTSG EAVKYKGSMDCAVKVVKSEGFMSLMKGAGANILRGVAGAGVLAGFDKFKALYVKWRVMSA TSDLDRQIEQLQKCEIIKESEVKALCARAREILIEESNVQRIDSPVTVCGDIHGQFYDLQ ELFKVGGDIPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRIMLIRGNHESRQITQV YGFYDECLRKYGSVAVWRYCTEIFDYLSLSAIIDGTIFCVHGGLSPSIQTLDQIRSIDRK QEVPHDGPMCDLLWSDPEDTQGWGVSPRGAGYLFGSDVVQQFNTANAIDLICRAHQLVME GYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQRNFTIFEAAPQEQRGKPQADYFL XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMQNDAGEYVDM YIPRKCSASNRIIAAKDHAAIQINLVEVDEK-GRMTGQHKTYAVSGDIRRMGESDDSLNN LCKRDGILPKMARGPKKHLKRVVAPRQWMLDKLGGVFAPRPSCGPHKLRECMPLAIFLRN RLHYALTYEEVKKILAQRLVKIDGKVRTDKTYPAGFMDVISIEKTGENFRYIYDVKGRFT THRITPEEAKYKLCKVKKVLVGLKGVPSIVTNDGRTIRYPDPLVKVNDTIKIXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXMTSSYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVR GKNVVVLGVEKKAVAKLQEDRTVRKIALLDDHVALAFAGLTADARILISRARLECQSHKL TVEDPVTVEYITRYIAQLKQKYTQSNGRRPFGLSTLIVGFDGTPRLYQTDPSGTHFEWMA NAIGRSSKTVREFLEKNYSPEVASDKETIKLAVRALLEVVQSGSKNMEVAVMRKDRPLEI MSTKDIDDLIKEIEKEKEEEAEKKKKKGG--LGDKKDDKDKKKKYEPPVPTRVGKKKKRV KGPEAANKLPQVTPHTRCRLKLLKLERIKDYLLMEEEFIKNQERLKPQEEKQEEERSKVD DLRGTPMSVGSLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDQLEPGCSVLLNHKVHAVV GVLSDDTDPMVTVMKLEKAPQETYADIGGLDQQIQEIKESVELPLTHPEYYEEMGIKPPK GVILYGAPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPS IVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSKGDVKVIMATNRIETLDPA LIRPGRIDRKIEFPLPDEKTKRRIFAIHTGRMTLADDVSLEDYIMAKDDLSGADIKAICT EAGLLALRERRMKVTSEDFKKAKENVLYRKNEGTPEGLYL-RKPYSPFQISNAADYALAR VDDLINWGRKSSLWPLTFGLACCAIEMMHFAAPRYDMDRFGVVFRASPRQADCIIVAGTV TNKMAPALRKIYDQMPDPKWVISMGSCANGGGYYHYSYSVVRGCDRIIPVDIYVPGCPPT AEALLYAILQLQKKIKRMTLVQSWYRRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------KK TTESINSRLALVMKSGKYVLGHQQTLKTLRQGKAKLVIIAQNTPPLRRSEIEYYAMLAKT GVHHYNGTNIELGTACGKYFRVTTLSITDPG-----------MTEYKLVVVGAGGVGKSA LTIQLIQNHFVEEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGF LCIFAVNNAKSFEDINQYREQIKRVKDADEVPMVLVGNKVDLSSRNVDTKLARSKAESFS IPYVETSAKTRQGVDDAFFTLVREIRKYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKIELCS FSGFKIYPGHGSRVVKVDGKTFQFLNAKCAKAHLAKRNPRKVEWTVLYRRKHKKGITEEV SKKKTKKATKFQRAITGASLADIMAKRNQKPEVRQAQREQAIRAAKEKAKAKAKSQPRVG GKRMKLNIAYPATGCQKLIDVDDERRLRPFFDKRLATEVCADCLGEEWKGYVVKITGGND KQGFPMMQGVLTNQRVRLLLSNGHPCYRMRRDGERRRKSVRGCITDSNLSVISLVIVKKG EQEIPGLTDTTVPRRLGPKRASKIRKLFNLDKKDDVRQYVVRKPLPPQTKAPKIQRLVTP LVLQRKRHRVALKRRRDVKRREEAAEYQKLLAQRLKEAKERKMERKRSASHSAKVKAKDL RGKKKDELEKQLNDLKTELSQLRVAKVTGGAASKLAKICAVRKSIARVLTVINQTQKDNL RKFYKPKDLRKKLTRAMRRALTPYELNLKSAKELKKRMAFPERVYAVKXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------ --------------------------------KFKIFVNFGIPFSKRFLKYLTKKFLKKN NLRDWLRVVANFKESYEVRFFQINNEGDEDEAAKXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPKLIKFSELKENNNSKSCWLAIHNEIYDIT KFLEDHPGGEEVLLEQAGGYATEAFDDVGHSTDAKEIMKQYHIGTLAEEDRKSWTSWLIP LAIAAAVAFFYRYFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKKLQKQLEFLEVQEEYIKDEQKNL KKEYLHAQEEVKRIQSVPLVIGQFLEAVDQNNGIVGSTTGSNYYVRILSTIDRELLKPSA SVALHKHSNALVDVLPPEADSSISMLSADEKPNISYADIGGMDIQKQEVREAVELPLTHF ELYKQIGIDPPRGVLMFGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVR DVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTVNVKVI MATNRADTLDPALLRPGRLDRKIEFPFPDRRQKRLIFSTITSKMNLSDEIDLEDYISRPE KISGADINAIFQEAGMQAVRENRYVVLGKDFEKGYKNNTKKDEQEHEFYRXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXSKRKSGMLEDLRNVEFETSEEVDALPTFDSMGLREDLLRGIYAYG FEKPSAIQQRAIKPIVKGRDVIAQAQSGTGKTATFSISILQNIDTQLRETQALVLSPTRE LATQIQKVLLALGDYMNIQCHSCIGGTNVGEDIRKLDYGQHVVSGTPGRVFDMIRRRNLR TRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPGTQVVLISATLPHEILEMTSKFMTDPI RILVKRDELTLEGLKQYFVAVEREEWKFETLTDLYDTLTITQAVIFCNTKRKVEWLTEKM RGNNFTVSNMHGDMPQKEREAVMKEFRSGASRVLITTDIWARGIDVQQVALVINYDLPNN RELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMKVEDLIVTIRRP FDPVIHDLDPNFRLTRFSDLKGGCKIPNDALLRMLEPFRELLESEQSHFQYIAPSARIGV GMDSCITPIRHGGLSIVQTTSCMYPIIDDPYMLGKVVCSAVLSNLFAMGVTECDNMLMNI SVSQKMTERERDIVIPLIMNGFKDCAEETGAGVNGGQTIVNPWMFIGGTATSICQSNEYI MPDNAAIGDVLVLTKPLGTLVAATSYQWLDLPEKWNRIKLVVGEDDVRKAYQRAMFSMAR LNRIAALLMHKYNAHGATDIGGYGLLGHANKLASIQKNEVGFVIHNLPIIAKMAAVSKAC GNMFGLLQGHSAETSGGLLISLPREQAAAFCKDIEKQEGYQAWIIGIVERGNRTARIIDK PRVIEVPAKDRDFLICLMKSAFGFYITIDAHAEDCFFDRVSSGTKLSLMFEVVEGGFLDI DVHISGPDGKVIYSGERESNGKYTFAAHMDGVYKYCFSNKMSTMTPKVVKFSMDLGEKSK ATQNKLEEMIDQLSGALKAVKHEQEYMEVRERIHRSINDSTNSRVVMWSAFEALVLLAMT LGQVYYLKRFFEVRRVIMSATLQPYLKAVRNTLTAAICVENFSSQVVERHNKPEVEVRTS KELLLTPVVISRNEKEKVLVEGSINSLRISIAIKQADEIEKILCKKFMRFMMMRADNFVV LRRKPVEGYDISFLITNFHTEQMYKHKVVDFVIHFMEEIDKEISEMKLALNSRARISAEE FLKRF------------------------------------------------------- -----------------------------------ASSFKNLDSWRDEFLIQASPRDSEH FPFVVVGNKIDLENRAVTTKRAQQWCESKNHAPYFETSAKDAINVEQAFQTVARNALAHE ADTEMYNEFPEPFTLSGDSGGSNCS-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------------- ------------------------------------------------------------ ---------------------------------------------------MRVGVDRNK YQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVEVPLLHPERFVNLGI EPPKGVLLFGPPGTGKTLCARAVSNRTDACFIRVIGSELVQKYVGEGARMVRELFEMART KKACIVFFDEINAIGGARYDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDT LDPALTRPGRLDRKVEFGLPDLEGRTNIFKIHARSMSVEKDIRYELLARLCPNSTGAEIR SVCTEAGMFAIRARRKMATEKDFLDAVNKVIKAYAKFSATPRYMTYNMGAEKIHINIVVI GHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITI DISLWKFETAKYYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQT REHALLAYTLGVKQLIVGVNKMDSTEPPYSHDRFEEIKKEVGAYIKKVGYNPDTVAFVPI SGWNGDNM--------------------------------------------IGGIGTVP VGRVETGTLKAGTVVTFAPVNLTTEVKSVEMHHQALEEALPGDNVGFNVKNVSVKDIRRG NVCGDSKNDPPRETEEFKAQVIIMNHPGQISAGYAPVVDCHTAHIACKFRDLLEKIDRRS GKKIEDNPTNVKAGDAAIVNMVPQKPMCVESFVEYPPLGRFAVRDMRQTVAVGVIKGVKK RDAGQSKVTKSAQKAELEQLRQEAEHLKNQIREARKGMADMSLAQLTASIEPVGRIQMRT RRTLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDGYTTNKMHAIPLRSSWVMTCAYAP SGNYVACGGLDNICSIYSLKTREGNVRVSRELSGHNGYLSCCRFLDDNQIVTSSGDMTCA LXDIETGQXTT------------------------------------------------- ------------------------------------------------------------ ---DFNCNVWDTLKQDRAGVLAGHDNRVSCLGVTEDGTAVATGSWDSFLKIWN------- ------------------------QPVHDLTIGVEFGARMIGIDGKQIKLQIWDTAGQES FRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARR DVKREEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYQKIQEGVFDINNEANGIKI GPQHFQANASGGGGSGQSGSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPKQ IQEIKDFLLTARRQDAKSVKIKKNYKFKVRCSRYLYTLVINDPEKAEKLRQSLPPGLQVK DLKMSKISRDSLLEGVNAVLTKKRKFVETVELQISLKNYDPQKDKRFSGTVRLRNVPRPK MAVCVLGDQQHCDEAKANNIECMDAEALKKLNKNKKLIKKLAKKYDAFLASDSLIKQIPR ILGPGLNKAGKFPSMISHGESMTGKVEEVKATIKFQMKKVLCLAVAVGHVDMSPEELASN VTMSINFLVSLLKKNWQNVRSLYIKSTMGPPQRLY------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYAGVQGTRPVTPPKGAAKGK GKMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------KSKLYCIYVAIGQ KRSTVAQIVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCAMGEYFRDNGKHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDHFGGGSLTALPIIE TQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQMRAMKQVAG SMKLDLAQYREVAAFAQFGSDLDAATQALLNKGVRLTELLKQGQYCPMA----------- ------------------------------------------------------------ MEALYSIPYSVLECPNLKIKKPSWLHMPSSMVVFSLILASYFLVTGGIIYDVIVEPPSIG STTDERGNSRPVAFMQYRVNGQYIMEGLASSFLFSLGGLGFIILDQTNKPTMPRLNRIIL LSVGFVSILISFFMCRVFMRMKLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPLVIDGKGHLLG RLAATTAKALLQGQKIVVVRCEGIEMSGSFYRKKLEYLDFLRKRMNTNPKRGPYHFRAPR KIFWRTVRGMLPHKLHRGKEALNRLQAFEGVPPPYDKQKRMVVPSALRVIRLKPRRKFCQ LSRLSSEVGWKYQAVISTLERRRKLKSTIFHKKRVQERKLLEQAKKVSEYQNIIESFGHX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIKLDTTLALIKPDAIVI EIEDAILRAGFVVLQKRRLKLSPEKASEFYEEHLGKSFFSHLISFMSSGPIMALLLTKKD AVKEWRNLIGPTNSEKAREVQPDCLRARFGTDGQRNALHGSDSNSSALREIRFFFPNALL EMNPL-HKMEEYLDGVVRSTLVKGLAALCHNKPLNPVVWLADWLDNNNPNKPKVQMFEAR LIQGSLLRKVLEAIKDLLTEAAWDCNGTGISLQAMDSSHVSLVSLCLKADGFDTYRCDRN ITMGINLSSMSKILKCAGNEDAVTVKASDNADTITFMFESPNGDKVSDYEMKLMDLDTEH LGIPETNYSCVVKMPSAEFQRICRDLSQIGGSVAICCTKEGVRFSATGDLGTGNIKLAQS SNIDKEEEAVIIDMQEAVSLNFALRYLNFFTKATPLSPQVCLSMSADVPLVVEYKIPNMG YIRYYLAPKIEDNEEAVGAACFHSTPTVSKGKVVAVIGAVVDVQFDGELPSILNALEVEN RPSRLILEVAQHLGESTCRTIAMDGTEGLVRGEVCVDTGSPIRIPVGPETLGRIINVIGE PIDERGPVNAKHFAEIHADAPEFVEMSVEQEILETGIKVVDMLAPYAKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIMSGVIDLKGDKSKVSLVYG QMNEPPGARARVALTGLTVAEYFRDKEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIA ELGIYPAVDPLDSTSRILDPNIVGQEHYAVARGVQKILQDYKSLQDIIAILGMDELSEDD KLTVARARKIQRFLSQPFQVAEVFTGSEGKLVPLKESIKGFKMILNGELDHLPEVAFYMV GPIEEVIQKAERLAEER-LMPKQNRVKIYEHLFREGVLVAKKDFHAAKHTELDVPNLHVI KAVQSLVSKKYVKEQFCWRHYYWSLTNEGIAYLREFLHLPPEIVPTTLKRQ-PGDERPGY RRG-GPDKRGEAGAGANMGKEQSKLKPEILEDLRKNTAFTDEEIKEWYKGFMKDCPSGKL TKDEFKKIYANFFPSGDASVFAGHVFRTFDTNNDGTIDFREFLCALSVTSRGNLEQKLKW AFNMYDLDGNGFISKREMLEIVSAIYKMVGNAVKMPDDESTPEKRTDKIFRQMDKNLDDK LSIQEFIDGAMSDSTIVQLLQCD-MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNL TGLNEQVPHYRQAIDMILDLEPDDGLDDNPNQSDLIEQAAEMLYGLIHARYIMTNRGIAQ MIEKWQQGEFGYCPRVYCENQPTLPIGLSDVPGESMVKLYCPKCQDVFVPKSSRHHHTDG AYFGTGFPHMLFMVHPEYRPKRPTNQFVSRLYGFKIHPLAYELQSQAAANFKTSYTNNKR MTNSKGYRRGTRHLFSRKFRTKGVIPLSTYLKTYKVGDMVDIKGNGAVQKGMPHKSYHGR TGTVYNVTQHAVGVIVNKRVKGRILDKRINVRIEHVKHSACRSDFLKRVSENEKLKKEAK AQVVCKRQPQQPRSGHFVSTKFNKPQVLEPIPYEFLAXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-AAPAKIAKIEVKPKKD-ELEQQ EAIEKIDEVQNEIDLLNEKASDEILKVEQKYVKLRQPFYQKRSELIEKIPNFWATAFINH HKLSALLTDEDEEVFQYLTKLEVQEFDDIKSGYSIIFHFKENEYFKNSTIVKEFRMNSSK STPIQWKPGKDLTKKSKKRAHEESESFFSWFSDNGEAGIDELGEVIKDDVWAYPLPYYLX SEMDEGEEEDDGEDNVGKKLTKQEELLLQDFSRNVSTKSSALFCGNAFIVSAIPIWLFWR IHQMDLYVFFAIFTLISTYLVAMAYKNVKFVLKHKVALKRGEAVSREVMRKVADDKKMSK QEKEERVLWKKNEVADYEATTFSIFYNNAVFLLLVVVCSFYILRSFSPVLNYSLTMFAAS GLLALFSTSSKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFLTRSEYDRGVNTF SPEGRLFQVEYAIEAIKLGSTAIGIQTSQGVVLAVEKRVTSTLIEPSSIEKILEIDSHIG CAMSGLVADSRTMIDKARLEAQHHWFTYNQLMRVESVTQAVSNLALQFGDDDAEAGAMSR PFGVALLIAGIDDLGPQLFHMDPSGTFIQYDAKAIGSGSEGAQQTLQEVYHKSMTLDEAC VEVLKILKQVMEEKLNATNIEMATVTRENNFKMMTKEDLQNIIDKLAMRTWELSNNIEAI ASIDDIYRYDEKQQRDILTAKPWEKDPHYFSSIKISALALLKMVMHARSGGNLEIMGLLL GKVDANNMIVMDSFALPVEGTETRVNAQAQAYEYMAAYIEAAKQVGRLENAIGWYHSHPG YGCWLSGIDVGTQMLNQQFQEPFVAIVIDPIRTISAGKVNLGAFRTYPKGYKPPDEGPSE YQSIPLNKIEDFGVHCKQYYPLEVSYFKSSLDRRLLELLWNKYWVNTLSSCSLLTNADYT TAQIFDLTDKLEQSENYLGRITAWGDKTDDKLSKATRDCCKNTMESIHGMMTQVIKHKLF NQIGGLPRRILKETQRLRAEPVPGIEATPDESNARYFHVIVVGPKDSPYEGGVFKLELFL PEEYPMSAPKVRFMTRIYHPNIDKLGRICLDILKEKWSPALQIRTVLLSIQALLSAPNPD DPLANDVAEQWKVNEAQAIETARQWTRRYAADHEELLDYEEEEQEENKEVKGTYVSIHSS GFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGLDVVCQAKSGMGKTAVFVLATLQ QLEVVDKQVSVLVMCHTRELAFQISKEYERFSKYMNGVKISVFFGGMAITKDETTLKNNC PHIVVGTPGRILALVKSLDLKHLXHFILDECDKMLDQLDMRRDIXEIFKMTPHEKQVMMF SATL--------------PMQVYVDDDSELTLHALQHHICKV------------------ ------------------------------------------------------------ ----------------------------------------------------PPSFADLG KSARDLFSKGYHFGLFKVDVKTKTTNGVEFNTAGQSSHDTGLFQGNLESKYKLKEYGATF KETWNTDGNLGCEVSVEDQLVEGLKLGLEAKFGVSSGKKSGKAKSEYKNDFFHTN--LDF DLMSYGLLGSVVFGHNGFLGGFQLQYDKSLLSQSNVAVGYVKDDIDIHLGVKGCNEYVGS VFHKINKDLETGVQMSWLAGSGETAFGFGTKYNLDKDTTFKAKVDNSSRVGLSYQQRLRP GVTLTMSTLLEGRTLTAGGHKFGIALEFEALSARDKTLQDYRKKLLEHKELEARLKEMRE SLKELTKQYDKS-----------------------------------------------K LKAGTRVALDMTTLTIMRYLPREVDPLVYNMSTEDPGNISYTQIGGLSEQIRELREVIEL PLMNPELFQRVGITPPKGCLLFGPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIGES ARLIREMFGYGRDHQPCIIFMDEIDAIRRFSEGTSADREIQRTLMELLNQMDGFDALGQV KIIMATNRPDTLDPALLRPGRLDRKIEIPLPNEQARLEIIKIHASGISKHGEIDWEAVVK LSDDFNGADLRNVCTEAGMFAIRAERDFVIEEDFLKAVRKVADNKKLETKLEYKPVMTES VFGVLSRFYNDYTQTTSKKLKIIDAYLLYILLTGAIQFFYCCLVGTFPFNSFLSGFISCV GSFVLAVCLRVQVNPSNKDVFFGISPERAFADFVFAHVILHLVVMNFIGXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXMLVLIIGDLHIPFRSNGIPTQFKKLLVPGKIQHILCTGNLCTKEI YDYLKTLANDIHIVRGDFDENSSFPEQKVVMVGKFRIGLCHGHQVVPWGDQESLSTLQRQ LDVDVLVTGHTHKFEIFERENKLFLNPGTATGAFSALENTIVPSFILLDVQASTVIAYLY QLIDGEVKVERTEFKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEQTFLMVKPEGVQRGLVGEIISRFEKKGF KLVAMKFVHAPSSHLEEHYKEHKGKPFFERVVKDMSSGPVVPMVFQGGIIKAARVMLGET DPLKSNPGTIRGDFGISVGRNICHGSDSLESSRREIQLWFKEGEVFQWKPVFHDFLYEPE AVKPKEAPKPVKDKALKAKKATLKGVHEKRSRKTRTSVHFKRPKTLSLPRTPKYPQKSHA SKPRYDQFKIIKYPLTTESAMKKIEDNNTLVFIVDPNATKHQIKWAVKKMYEITAARINT MVISTNNKKAYVRLAPDFDALDVANKIGIIMAPKQKMRLANEKHSKNVTNRGNVPKSLKQ EEEKLPVGPWLLGLFIFVVCGSAIFQIIQSIRMXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- ----------------------------------------------FRNFKIVYRRYAGL YFCICVDITDNNLVYSEAIHKFVEVLNEYFHKVCELDLVFNFYKVYSIVDEMFLAGEIRE TSQTKVLKQLLLLSSLEKPTIFSKIIDKTIQAKILYEDDECVAFEDAHPQAPKHFLVIPR KIITGISSDEKLIGHLMVVAKKLAKEDKGYRLVINNGPNGGQSVYHLHIHVLGGRQMKWP PMGGLLSYFSSLFGSKERRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVQYKN LKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSMDRDRIGISKQELVSMLEEDELKKAV LCIFANKQDIDGSMTVTEVANALGLAAIKNRRYQIFKTSAIKGDGLDEAMEWLANTLQSS KCLYFHIPQTQKKCFXEDIPDETIVVGKYKVEIFDPNSNQFIPSVSGLGMHVDVRDPDDK SMLSRTYASEGRFSFTSHMAGEHFVCLHANASNLFGTTQLRVHLNIQVGERANDYQEIAS KDKLSELQLRVRQLLDQVEMISKEQNYQRFREERFRETSESTNQRVLWWALAQLIILIVT GFWQMNHLKGFFKAKKLV----VNLEHEILLHPKYFGAHLLMTVKKKLFSEVEGTCSGKY GFIIAVTAIDNIGAGQLLPGRGFARFPVKYKAIVFRPFKGEVVEGVVTQVNKIGIFVEVG PLVCFISRQSIPADLEFDPSSNPPSYRGKDEDSVIQPDDDIRLKIVGTRVDAKEIFAIGT LMDDYLGLIN-------FTGYKRGLRNQHESTALLKIDGVFNKEETXFYLGKRCCYVYRA KNKTAVPNKKVANHLRVIWGKVVRPHGSSGAVRARFSSNLPAEAMGKRIRIMLYMAKKTY DLLFKLLLIGDSGVGKTCLLFRFSDDAFNTTFISTIGIDFKIKTVELGGKKIKLQIWDTA GQERFHTITTSYYRGAMGIILVYDITSSKTFDNISKWLRNIDEHANADVEKMILGNKCDM EDRRQVPKEKGEEIAQQHNIPFLETSAKSNINVERAFLHLAQAILDKMPQNEYIDLHRKR HGRRLDYEERKRKKEGRRAHEESRKAKKLRGLKAKLFNKKRHLEKIQIKKTLKMHEEKDT KQKAPEDMDPGARAKYLLDRELQQRAKILSNTIKEKRKEKAGKWDVPMPRVNAVSEADVF KVVKTGKSRRKGWKRMITKVCYVGDGFTRKPPKFERFIRPMCLRESKAHVTHPDLKATFH LPIIGVKKNPSAALYTQLGVITKGTIIEVNISDLGLVTTGGKVVWGKYAQVTNHPENDGC INAVLLVMSCRLQVSVYDDKAVDTGKTLAMPAVFRAPIRVDIVNTVHMDMLKNGRQPYAV SKKAGHQTSAESWGTGRAVARIPRVSGGGTNRSGQAAFGNMCRGGRMFAPTKTWRRWHRH INVDQRRYAICSAIAASGIPSLVMSKGHIVDSVPEFPLVLDDKVEEIKKTKEAVGVLRKL KVWPDIEKVKSSKRFRAGKGKMRNRARIQKRGPIVIYNKDNGITRAFRNIPGITLISVDR LNLLKLAPGGSVGRFAIWTESAFKQLDSIYGTWKKASEKKTGYNLPVPKMTNTDLSRILR SEEIQKALRAPLKDRPKRVLKKNPLKNMEALSKINPYGIAQKKAANHLKEKQAILDAKRG IATLDTGSKARPRKQVANAGEEELASKVLQIQTKRFYLDVKQNRRGRFIKIAEVGTGGKK SRLLFAMSTAAEFRNRLTEFSEHYASLGPPNAEKISEDGKLKSEVITKENRRYYLDLKEN TRGRFLRVSPLSRQRAQVAIPAQGMIEIRDALTDLLNEFGCGNQDVQDEIPESQSLKVEN KIFYFDIGENRRGRFMRISETNFRTAITIPENSWARFRDVLAEFADKIDKKARDAQMKNT INQKLVETGERERLKELLRTRLVECGWRDQLKLHCKEIVKQKGLENITVDDLVAEITPKG RALVPDQVKKELLQRIKAFLSQQS-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------------------- ---------------------------------------------AVTVIETPPMIIVGV TGYIETPKGLRTLTTIWAEHISDECKRRFYKNWYRSKKRAFSKASLKWTDEAGKKEIESD FNKLKKYCTVVRVLAHTQMKLMNRRQKKAHIMEIQLNGGTVPEKVEWARQHMEKAVPVKQ VFDTDEMIDCIGVTKGKGFKGVTSRWHTRKLQRKTHKGLRKVACIGAWHPSRVSFSVARA GQKGYHHRTEINKKIYRIGDGIHKEGDKIIKNNASTEHDITEKSITPMGGFPHYGEVKQD FVMIQGCCMGPKKRPITLRKSLLAQVKRKALEKTNLKLIDTTSKFGHGRFQTHEEKRNHM GLLKKDMQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGRPINLG LWDTAGQEDYDRLRPLSYPQTDVFLICFSLISPASFENVRAKWYPEVSHHCPSTPIVLVG TKLDLREDKETIDRLKDKKLSPITYPQGLAMAREIGAVKYLECSALTQKGLKTVFDEAIR AVLCPKPKPKKKKVCVLL---------------------------DL-LDKKKKKKKKPL DLSEIASALPEQQGSVKKKKKKEQSENDYTYEELLSRVFEIMREKNPDMIAGEKRKFVMK PPQVMRVGTKKTSFCNFAEICKMLHRQPKHLLAFLLFELGTSGSLDGNFQLIIKGRFQQK QIESVLRRYIREYVTCHTCKSPETMLQKDTRLYFLQCEMCGSRCSVASIKSGFQAVTGKR AAIRART-MDYAVEERMINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGK DYSVHRLILGTHTSDEQNHLLIASVQIPNENARFDVSHHDTEKGEFGGFGSVTGKIEIDI KINHEGEVNRARYMPQNPCVIATKTPSSDVLVFDYTKHPSKPDPSGECHPDLRLKGHLKE GYGLSWNHNTNGYLLSASDDHTICLWDINATPKEGRVVNAMSIFTGHTSVVEDVSWHLLH NSVFGSVSDDQKLMIWDIRTVNTNKPSHIVDAHTAEINCLSFNPYSEFILATGSADKTVA LWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEDQSAEDA EDGPSELLFIHGGHTAKISDFSWNQNEPWVICSVSEDNIMQVWQMAENIYNEEEPESAVG EIDMPAPSRARVYADVNNSRPRDYWDYEAHIVEWGQQSDYQIVTKIGRGKYSEVFEAMNI VLDQKCVIKILKPVKKSKIKREIKILENLRNGVNIINLLAVVKDPISRTPALIFEYINNT DFKQLYQTFSDYDIRYYTLETIKALDYCHSMGIMHRDVKPH------------------- ---------------RYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFKKEPFFHGHDNY DQLVRISKVLGTDELFEYIDKFQIVLDPRFNSILGRHSRKRLERFVNNDNQHLVSQEALD FLDKFFGYDHQQRLIAREAMDHPYF------SAPESLLKKRNLIAQKLALRKKQYFERAE KYAKEYQATEKDQLAFSRQARNNGNFYVPPESKIAFVIRIRGINGLHPKPRKILQLFRLR QINNGVFIKLNKATLNMLKIVEPYVTWGYPNLKSVKELIYKRGYGKIEGRRTPLVDNAIV EQKLGKKNIICVEDLVHEVFTAGANFKSATNFLWPFKLNTPNGGWRKKGNHFVDGGDFGN REDKINALLRRMMQFLLLFSRQGKLRLQKWYITSSDRAKKKITRELITTILSRKPKMCSF IEWRDMKIVYKRYASLYFCCCVEPDDNELIVLEIIHRFVELLDKYFGSVCELDIIFNFEK AYFMLDELMLGGEIQESSKKNVLKALTAQDLLQEETPQGFFEDHGLG------------- -----------------LRGFDPFMNLVIDEAFEELKNGEKNALGMVVVRGNSVGLLEAL ERIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMVDEA TKKQLASIPLLQTKAGPKDGELWVQRLKEEYQALIKYVQNNKSADNDWFRLESNKEGTRW FGKCWYIHELLKYEFEIEFDIPVLYPSIAPEIAIPSLDGKTAKMYRGGKICLTDHFKPLW ARNVPKFGIGHALALGLGPWLAVEIPDLINKGIIQHKE---------------------- ------------MIWKGLMIVTGSESPIVVVLSGSMEPAFYRGDILFLTNVEEDPIRVGD IVVFKIDGREIPIVHRTLRVHERDNGTIKFLTKGDNNQVDDRGLYAPGQLWLEKKDVVGR ARGYLPYIGMITIIMNDYPKFKYFTLAMLAIFALLHRE---MNPEYDYLFKLLLIGDSGV GKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYR GAHGIIIVYDVTDQESFNNIKQWLQEIDRYASENVNKLLVGNKSDLTTKKVVDFTTAKEY ADQLRIPFLETSAKSATNVEQAFVTMAAEIKSRMGPSGPAPNLKITSSTPVKSSSGGCCQ DNLEKEILRMSNDELVSRTRLLDNEVKIMKSEVMRISHELQAQKDKIKENTEKIKVNKTL PYLVSNVIELLDVDPQDQAEEEGANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDPEQL KPGDLVGVNKDSYLILETLPAEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELIEAVVLP MTHKDRFTALGIQPPKGVLLYGPPGTGKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGA KLVRDAFSLAKEKAPAIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQSNHD IKVIAATNRVDILDPALLRFGRLDRKIEFPAPNEEARARIMQIHSRKMNVNKDVNYEELA RCTDDFNGAQCKAVCVEAGMIALRRGAFELCHEDYMDAILEVQAKKKANLNYYAXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXFKTHQLAVTRDYISQPRLTY-TVSGVNGPLVILDGVKFPKFAE IVKLTLQDGSCRSGQVLEVSGXKAIVQVFEGTSGIDAKHTTCEFTGDILRIPVSEDMLRR VFNGSGKPVDKGPNVLAEDYLDIQGQPINPWSRIYPEEMIQTGISAIDGMNSIARGQKIP IFSANGLPHNEIAAQICRQGGLVKLPGKAVLDDHEDNFAIVFAAMGVNMETARFFKQDFE ENGSMDNVCLFLNLANDPTIERIITPRIALTTAEFLAYQCEKHVLVIMTDMSSYAEALRE VSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLT GYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGKDMTREDHADVSNQLYACYAIG KDVQAMKAVVGEEALTSEDLLYLEFLQKFEKTFITQSPYENRTIFETLEIGWQLLRIFPK EMLKRIPQPLMAKYYPRIVGGPNFVGIKFCQECNNMLYPKEDKDRKKLMYACRNCDFQMD ADSPYVYVNKLDHEIDELAHIVTDVIGDPTLPRTEDHPCPKCGHKEAVFFESESRRAEET MRLYYVCTSSICKHKWTE---YKVADINLADWGEKAIAIARNEMPGLMMMQKVYGPKKPL KGARIAGCLHMTVQTAVLIETLVELGAEVQWSSCNIFSTQDHAASAIAKRGIPVYAWKGE TDDEYFWCIEQTIFFAGGKPLNMILDDGGDLTNFVHEKYPQLLPGIKGISEETTTGVHNL YKMLAKGELKIPSINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGKVAVVAGYGDV GKGCATALRAFGARVIVSEIDPINALQAAMEGYEVTTVEEAVKEARLFVTTTGCKDIITG AHFPHMLDDAIVCNIGHFDIEVDVKWLNENSVSKENIKPQVDRYTLSNGRHIILLAEGRL VNLGCAMGHPSFVMSNSFTNQVLAQIELWTKADKYPLGVHFLPKKLDEEVAALHLNHLGV KLTKLSPEQAAYLGIPVEGPYKPDHYRYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXMAMSNMENLTPNVIRMVTKELAELEKNPPEGIRVTLNDSDITDIHAIIDGPEE TPYSGGAFEVKLILNRNFPQEPPKGYFVTKIFHPNVSSQGEICVNTLKRDWQPSYGIQHI LLTIKCLLIVPNPESALNEEAGKLLLEHYDDYFSRAKMFTDIHARP-------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------QPGFAGTLREGLPKFIKEEGVM GLYKGLVPLWGRQIPYTMMKFACFERTVEALYKFVVPKPRSDCSKGEQLLVTFCAGYIAG VFCAVVSHPADTIVSILNKQKGSTFLQVAKSLGFKAMWSGLFPRIIMIGTLTALQWFIYD SVKVYFRMPRPPPPEMPESLKKKL-HWVNERYVAVALLPLIPAALAYVLDTLLSAMMLHT HWRLSGVAQDYIHISVLALGGILYFNYTDIGFANAARLLYTKLXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------VKESQ AKDQYXKFVRFVQGTIADGAPVIPISAQLKFNIDAVCEYIVRKIPIPLRDFTSEPRLIVI RSFDVNKPGCECEDAKGGVAGGSILRGVLKVGQEIEVRPGIVSKDNEGKLTCRPIFAQIL SLFAEQNDLQFAVPGGLIGVGTSIDPTLCRADRMVGQILGTVNTLPEIYIELEISYFLLR RLLGVRTEGDKKAAKVQNLFKNEMLMVNIGSLSSGGKVLAVKKDLAKIGLTNPVCTDLGE KIALSRRVEKHWRLIGWGQIRRGVSVTPMAELLLDSSIRIWVFLPIVLITFLIGIIRHYA TILLSTEKKVEMQQISDSQVMMRSRMLRENGRVLPKQSFQIRKHFFNNESTGFFMKNPLT DPSMMAEMMKGNVTNVLPTIVIGGWITWAFSGFLTTKVPFPLTLRFKPMLQRGVELASLD ASWVSSASWYFLNVFGLRSMYSLILGHDNAADQTKPMQDQMTGMAMGMPPDPSKAFKAEW EALEICDHQWELENVEDDLMMFLWDWFAGVLSYLGLYKKSGKLVFLGLDNSGKTTLLHML KDSRMAQHVPTLHPTSEELSMGGMKFTTFDLGGHEQARRVWKDYFPAVDGIVFLIDSFDR SRFHEAKKELFGLINDEQIANSPILILGNKIDIPGACGEDEIRREFELYQVVTGPGVRPK SELRPVELFMCSVLKRTGYGNGFRWLAQYINMVRRNRPGTKAGDWCKWQDESFEEMESTL AVQQFIQQAIRHDYNNIDEILTPPENQDEGVWKYEHLRQFCMELNGLAVKLQLECNPDTC TQMTATEQWIFLCAAHKNPKECPAIDYTRHTLDGAACLLNSNKYFPSRVSIKEASVAKLG SVSRRVYRIFSHAYFHHRALFNEYENETALCKRFTTFVTKYNLMSKDYLIVPILDDQMPD IKLQSSDGEMFSVEEKIAKQSIMIKTMLEDNEADDDPVPLPNVNGSILKKVLQWCTFHKD DPPIPDDDDGKDRRTDDICSWDQEFLKVDQGTLFELILAANYLDIKGFLDVTCKTVANMI KGKTPGEIRKTFNFKNDFPPAEEEQVRRENEWCEEKNKRLSKGGKKGGKKKIVDPFSKKD WYDVKAPCMFTNRNIGKTIVSRTVGTKIASEGLKGRVFETSLADLQNDEVSFRKFKLISE EVQGKQVLTNFHGMDMTTDKLRSMVKKWQTLIEAHVDVKTTDGYLLRLFCIAFTARKQSS TKKTAYAQSTQVRAIRKKMVEIMKKEVEKSDLKEVVTKLIPDSIGKDIEKFCQGIYPLHD VFVRKVKVLKKPKFDIGKLLDLHGELPGK---DASEKIDRPGNFEPPVVDSVMSSSVVYI LDLKGKVLISRNYRGDIDSNVIDKFMPLVMEKEEEGCITPIIQHGNISFSYIKYNNLYLV SVTKKNANIVMVFQFLHKMVQVFLEYFKELEEESIRDNFVIIYELLDELMDFGYPQTTDS KILQEYITQEGHKLEIAPKPPMAVTNAVSWRSEGIKYRKNEVFLDVVESVNLLVSANGNV LRSEIVGAIKMRVYLSGMPELRLGLNDKVLFESTGRGKSKSVELEDVKFHQCVRLSRFDN DRTISFIPPDGEFELMSYRLNTHVKPLIWVESVIERHAHSRVEYMIKAKSQFKRRSTANN VEIIVPVPVDADSPKFKTTCGSCKYSPEQNAVIWTIKSFPGGKDYLMRAHFGLPSVTAED LEGKPPIHVHFEIPYFTVSGVQVRYLKIIEKSGYQALPWVRYITQNGDYQLRTQMGILEK ISEIESEMARTQKNKATMGHLGLLKARLAKLKRELIEPKGGGGATGEGFDVAKTGDARIG FVGFPSVGKSTLLTTLAGVYSEVAAYEFTTLTTVPGCIKYKGAKIQLLDLPGIIEGAKDG KGRGKQVIAVARTCSLIFMVLDVLKPLQHKKILEXELEGFGIRLNKTPPNITFKKKDKGG INLTATVAQSELDIDTVKAILGEYRVNNADVTLRHDATTEELIDVIEGNRIYIPCIYVLN KIDQIFIEELDLIYKIPHCVPISAHHKWNFDDLLERMWEYLMLVRVYTKPKGQLPDYNSP VVLREGHVTVEDFCNKLHRSIMKEFKYSLVWGESVKHQPQKVGKEHLLHDEDVIQIVKKX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXRIKVEKPVVDLDGDEMTRIIWSWIKDKLVLPYLDVEILYYDLGLPHRDATNDQVTIDA AHAIQKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPIICKTIPRL VPGWVKPIVIGRHAHGDQYKATDIVIKKLGKLELVFTSTDGKEERLEVYNFKDTGGVGLA MYNTDESISGFAHSCFQYSLXKRCPLYMS----------------------KGLQANYDE ANIWYEHRLIDDMVAQALKSSGGFVWACKNYDGDVQSDVVAQGYGSLGLMASVLMCPDGK TIESEAAHGTVTRHYREYQKGKPTSTNPVASIFAWTRGMEHRASLDGNDDLKRWCHGIEK ACVDVIDSGRMTKDLAGCIHGIKNVKEEHYLNTQDFLEVIKEEFDMGKLLSKIFGNKEMR ILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVKYKNVKFNIWDVGGQDKIRPLWR HYYTGTQGLIYVVDCADRDRVDEARQELHRIINDREMRDAIILVFANKQDLPDAMKPHEI QEKLGLTRIRDRNWYVQPSCATTGDGLYEGLTWLTSNIKT---------LQLLESHLEMR SYIEGYAPSQADSIVFRSLELSPEKFPNLARWRRHVAWFTGQVYRFPGEYKNLKDLGFCS VKTSDDDDDFELFGSEKERVKQERLKAYEEKKKTQVIAKSNIILDVKPWDDETDMAKMEE LVRSIETDGLLWGASKLVHLAYGIKKLQITCVVEDDKVGTDFLEEEITKFEDYVQSVDIA AFNKIKIQEVREVTRIERVGAHSHIRGLGLDDALSARNVSQGMVGQISARRAAGIATVMI KEGXIAGRGMLIAGHPGTGKTAIAMGMAQALGADTPFTSMAGSEIFSLEMSKTEALTQAF RKSIGVRIKEETEIIEGEVVEIQVDRPATGMGAKVGKLTLKTTEMETVYDLGQKMIESLT KEKVQAGDIITIDKATGKITKLGRSFTRARDYDAMSANTKYVQCPEGELQKRKEVVHTVS LHEIDVINSRTQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKADIVPGVLFIDEVHM LDIECFSFLNRALESDMAPILIVATNRGITRIRGTHYVSPHGMPIDLLDRLLIISTSPYE EKDIXEILXIRCE----------------------------------------------- -------------------------------MAQYDLTNLMAPYLDRHMVLPLMEFASGK DIYDENSLLDGKLELLENTKMVDYSTDVYKARHPDQEPPQRMLEKRGEVLRNMKELEAEA DSLINILANEETNIQNTRDGRQLLEYLSKK-GFRMEMLDTLYACAKFHYECGNYSRSSQY LYFVRIMLPTNDANYMNTLWGKLASDILMQDWENAIDDVTKLKDTLDNNLILLQHRTWLI HWSLFVYFNHSKGRDYIIDIFLYSPNYLNAIQTMCPHIMRYVTAAVITNRQLLKDLVRVI TQESYTYRDPITEFLECLYVNFDFEGAQQKLKECEVVITNDFFLVGCLKDFIDNARLFIF EAFCKIHNRISISQFAEKLNMEEEEAERWIANLITATHLDAKIDCKNGLVIMGTPELNVH QQIIEKTKNLALKTQVQVLNLEKKCSIRDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXMPKYYCDYCDTYLTHDSPSVRKTHCGGRKHKENVCTYYQKWLE EQVQKLVDDTTAAFKAGKLPSNPYLNMGAMLPPPMGP-AGMAGPPGPMPNP--GGPM--L RPPMGPIPPVMPMGGAPEPLSLAGDVQKAVELLEILQKSGEFDKLAALQKVLQSEFCVAV REVYEHVYETVDLSGSPEVRANATAKATVAAFAASEGHAHPRIVELPKTEEGLGFNVMGG KEQNSPIYISRIIPGGVADRHGSLKRGDQLLSVNGVSVEGEPHEKAVELLKAAQGSVKLV VRYTPKVLEEMEARFDRQRLARRKQ----------------------------------- ------------------------------------------------------------ -------------------------------------------------LLTKKEIRCKD DVLTHLYTLVIRPDNTYEVKIDNKKEESGTLEDDWDFLEPKTIKDPEAKKPEDWDERENI DDPNDKKPEDWDKPEHIPDSTATKPEDWDDEMDGEWEPPMVDNPEYKGEWKPKQIPNPSY KGKWVHPEISNPSYVPDDKLYKYTDIGAIGFDLWQVKSGTIFDNVLITDDEAYAEKVGEE TWGITKVGEQKMKDKADEEEAKLREEEAKKQEAEEKSKEEDEDDMEPMLLDPTMYLVKGI LIMDNDGNRLFATYYDSTFPTIKEQKNLFSKTHKANAEIIMLEGLTIVYKLSVDLLFYII GASHENELILMSVLNCLYDSVSTMLHKNVEKRSLLDNLDGVFLTIDEICDSGLILESDPL VVSQRACYRMDDIPLGEQTLASVIQSAKDQIKWPLLKMNIFRLVGDLSHLAAIIILLLKI WKSRSCAGLSGKSQIMFAMVYTTRYLDLFTTFVSLYNSVMKVIFVVSSYVTVYLMYSKFK ATYDGNHDTFRVEFLVTPVAGLAVLINHELSFLEILWTFSIYLESVAILPQLFMISKTGE AETITSHYLFALGIYRALYILNWVYRYYTESFFDLIAVVAGCVQTVLYCDFFYLYITKVW KGKRLTIPAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------L KEGAKKRKGRGF-TRMSVEQFESMDAQEGGPQRSVEGWIVFITNINEEAQEDDVREKFEE FGEIKNLHLNMDRRTGYVKGYALVEYNTFKEAEAAIHTLNGAEICGQKIGVDWTFVKGST KKRMSYQLYRNTTLGHTLQESLDELIQIGQITPQLALKVLLQFDKSINQALSNRVNKKIS FKADLNTYRFCDNVWTFVLNNAEFRKVDKVKIVACDGKGVFLFTSESVGEGHPDKICDQV SDAVLDAHLSQDPNAKVACETAAKTGMIMLLGEITSKANVDYQKVVRDTIKHIGYDDSSK GFDYRTCNVLSALEEQSPEIAQGVHIGRDEDDIGAGDQGLMFGYATDETEECMPLTIMLA HWLNQKISELRRSGVLPWARPDSKTQVTCEYRMLKGACIPQRVHTVVISIQHSEDVTLDK IKKDLREHVISAVIPAKYLDDKTIYHLNPSGKFVIGGPQGDAGLTGRKIIVDTYGGWGAH GGGAFSGKDFTKVDRSAAYAARWVAKSLVKAGLCKRVLVQVSYAIGVAKPLSVFISSYGT GVKSDAELLKIVNENFDLRPGRIVKDLDLKRPIYSKTASYGHFGRSEFTWEQPKHLKFXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMSTYKIVMVRHGESAWNAENRFCGWFDADLADSGVAEAKKAAERLKEKGFLFDVAYT SVLKRAIKTLFYIQEGLDLHWIPVHKHWRLNERMYGALQGLNKAETAAKHGEDQVKIWRR SYDVPPPPVDRNSKYYPGSDPKYQLVDTKLIPVAECLKDTVARALPYWHDVIVPEIKDGK RVIIAAHGNSLRALVKYLDNLTDDEIMALNIPTGIPLVYELNSDLQPVKHYYLASDEEVK AAIDKVANQGKAK----DIIYPKAEFIETASGNKVSRLSILCGSQNIVLNGKTVIMTDSI IRGDLANVRIGKHCIVGKRAVIRPPFKKFSKGVAFFPLHIGDNVIIGEDSVINAAQIGSY VHIGKNCVIGRRCVLKDCCSIADNTVLPPETVVPPFSLFSGNPGMSFFFGTRNYKTFKPK KHIPEGSHQHDLMKHAAATLGSGNLRLAVALPEGEDLNEWVAVNTVDFFNQINMLYGTIT EYCLEDTCPVMSAGKKYEYHWADGTTIKKPIKCSAPKYIDYMMTWVQDQLDDESIFPSKI GVPFPKNFLSIAKTILKRLFRVYAHIYHQHFEQVMQLQEEAHLNTSFKHFIYFVQEFSLV DKKELMPLQELIEKLT---MGIDICHKHDRKVHRTEAKSKDNMLRLLVKLYKFLARRTSS KFNAIVFKRLIMSKNNKPPISISRLARHMRKEGREGKTAVVVGTITDDKRILSIPKLTVC ALRVTNTARTRILKAGGTVMTFDQLAMKAPKGENTVLVQGERKAREAYRHFGPAPGVPHS HTKPYVRSKGRKFERARGRRKSRGYK-DVTESVTDGSYFMASFVKLLKKILLETPWATGS EVKRNIVAATERLNTLFRNEPSFENISAKFLKVFEEECAKEVVNELVTEVEGCRQSRNYV QTNDVIRTVEMFLKNKFKVWIIGSNGREMAERLRTSGIEVEVRNETFLMTLMSSATKVIV GAHAAKVDSGFMCLGTYDVAMVAKKFNRPVIACVPSFKFTTREECCSETSANVFLGINDV QNPLFDFVPATFVGTTVSNV-----------------XXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------- ------------------------------------------------------------ --------------------------------------ELQEQQRLEEMERRRKHEKLLR MKQQEEKIKQDKETAEKIAAKVYAQQLLIDLVPSVLATLSENGFFHDPVEREIETNFFPS LLRNVRKNLNTHLTARRLLDGLIRETVIKR------XXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSAYKEMQSFWDKNLGRPNSPWIIYKPHL PMLTSFCHRFTGISMGVVFYAFSIATFVAPGDFPSYVEFIKNLQLPMALLFPAKTIVAFP LVYHYINGIRHLTWDAGRGYELGTQYKSGTIILASISYW--------------------- ------------------------------------------------------------ ------RYINGTRLDDRIIRTDWDAGFVEGRQYGRGKGGGQVRDEYRTDYDIGRGGYGKL IQQKL------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------SFVKFSPNGKYILAATLDNSLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG KWIVSGSEDHLVYIWNLQTKEIVQKLDGHSDAVLCCACHPTENIIASAALENDKTIKLWR SDVMIIYKDAFSGDELFSDSVPNIVYKVKGTDESAIGGNKSQGVDIVLNGKKDYMTHIKT YMKQVKEYQLFCGLALMKWDGPYMYFFKHGLLEEKVMAVEFDGGVVIGADSRTTSGSYVA NRVTDKLTKVSDLIYCCRSGSAADTQAIADVVSYHMSVHKMEYGGQPLVKSAAKLFQELC YSYRDQMSAGIICAGWDPKEGGQVYCIPLGGMCIRQPFTIGGSGSTYIYGYVDATYKEKM NVKECLEFTANAVSLAIGRDGSS-GIIRLAVITKDGVERHTLMPNQHPRF---------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------KVPYAEIGSKTLVFAVYDFDRFSKHDQIGQVLVPLNSVD LGRVVEEWRDLTSPESE-EKENKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLS- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------NPDNIVFVMDA SIGQACEAQARAFKERVDVASVIVTKLDSHAKGGGALSAVTKSPIIFIGTGEHIDDFEAF KVQPFVSKLLGMGDIEGLMDKVSELKLDDEDLMKKLKQ---------------GQFTLRD MYEQFQNIMMSIMSYNGAAIIAMKGKNCVAIACDRRFGIQAQTVAMDFDKVFRVGQRLFI GLGGLATDVQTVYEKLMFRVNLYELRENRRVKPQTLLSMVSSFLYEYRFGPYFIEPVIAG LDSKTGEPFVASLDLIGCPMVTEDFVVSGTCTEQMYGMCESLWKPDMTPDELTEVISQAL LNAQDRDALSGWGGIVKIIEMDKVTTKVLKARMD-------------------------- ------------------------------------------------------------ ----------------------------------------------------KWPAPGGI ILPDRATLYVCAIEDRQYKDEKINWWDNVYGFDMSCIRKVAISEPLVDVVDPKQVVTNSC LLKEVDMYTVKDGDLEFSAPFSLTCKRNDYIQAFVTYFNIDFTCCHRPTGFSTAPGSRYT HWKQTDDYLTVKANEDITGVFHIKPNSRNNRDLDFSLDVSFQGELSSLDGTMDYKMRMVK EDRSTWKAGYFTKIIQLLDEYPRCLIVGADNVGSKQMQKIRIALRVLMGKNTMMRKAIRG HLEQNPNLEKLLPHIKGNVGLVFTKGELNDVRQIIQENKVAAPAKAGAIAPLDVTVPAQN TSLGPEKTSFFQALAIPTKISKGTIEILNDVKLIKAGDKVGASEATLLNMLNISPFTYGL VIDQVYDSGTIFDVNILDITSDDIKARFLLGVAKIASLSLKIGYPTMASVPHSIVNGFKN LLAIAAVTEVTFKEAESMKEGIPRGKLIAVIGDEDTCTGFLLGGIGELNKQREPNFLVVE KSTSISEIEDAFKRFTNRDDIAIVLINQTIAELIHHVVDVYTGTIPAILEIPSKEHPYDP SNDSILRRAKGMFSGEDSRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXMTYFTSWEEFSKEVERLYTEDPMRCRYVIKYNHAKGQVVVKMTDDRVCLQYR SEHAQDVRKIEKFTGQLMRHMASKDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------- ------------------------------------VNQKKLDTETKILQANVVQFSKQA NQWLSLIKDFNQLIKEIGDVENWSRSIEADTRTISSALEYAYKEKFVEKQINGDKNGGKR KVAVRRQPKSYPTQEKAWKLRTPFSQHKRNIRASITPGTVLILVAGRHKGKRVVFLKQLQ SGLLLVTGPYHVNGCPLRRINQIYVIATKTKLDISGMNIPERLTDSYFKRKVLKKPKHAE GEIFDNKKEEYEVSAERKADQIDVDTQLLKVIRSHPDKKFLIGYLSTFFSIKTGEYPHKM LFMSWLFGRKKTPQEMLRQSQRALNKAMRDIDRERQGMENQEKKVIMDIKKMAKQGQMDA VKILAKDLVRTRKYVKKFILMRANIQAVSLKIQTLKSNDAMAQAMKGVTKAMMTMNKQMK LPQIQQIMREFEKQSEIMDMKEEMMNDAIDDAMGDEDDEEESEAIVSQVLDELGLQMADQ LSDLPSTGNK-GKQPTGLSDADLDIEAR-------XXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXX--DRAVNLYPLTNYTFGTKDPQYEKDQSVTARFD RMKEDFQMSGMRRSAEGVLIVHEHRLPHVLLLQLGSSFFKLPGGELKAGEDPVEGLKRLL TEMLGRQDQPPVDWVIEDTIANWWRPNFEPPQYPYIPAHITKPKEHKRLYLVQLPEKALF AVPRNYKLVAAPLFELYDNAAGYGPIISCLPQNLSRFNFIY------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------VGRIADRGYEYVA AREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVC TTVAIAIVAETCSPFTVLPALMNEYRVPELNVQNGVLKSLSFLFEYIGEMGKDYVYAVTP LLEDALMDRDLVHRQTAMSAIGHLALGVHGFGCEDALTHLMNYLWPNVFETSPHVIQAFM SAVEGMRLGLGPTKVLQYLLQGLFHPARKVRDVYWKVYNSLYIGAEDALVPSYPRISNDE KNKYIRYELDYVL----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------ESGSPRRTTCLKYLVLANMLMKSGIN PFDSQEAKPYKNNPEMLAMTNLVNAYQNNDINEFEKILRMNRENIMEDPFIREHIEDLLR NIRTQVLIKLIKPYTRIHIPFISQELNIDASEVECLLVSCILDNTIHGRIDQVNQLLELE TGTARYNAVHKWSNQIASLHEAIANRM-VLLMGKSGAGKTSMRSIIFANFIARDTRRLGA TIEVEHSHVRFLGNLVLNLWDCGGQEAFLESYLSAQKENIFRSVEVLIYVFDVESREIDK DLADYKRCLEALSSYSPEAKVFCLIHKMDLIQTNEQKKLFEDRQSRLTGLTEDIATSIWD ETLYKAWSAIVYQLIPNIKQIETSLVKFAELLEADEILLFEKATFLVICHCERKNHPDIH RFEKISNIIKQFKISCSKVTASFNSIEVRNSKFAAYIESFTPNTYVLVVTSDPEITSVVT LSNIRNGQKHFEKLEKADV----------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------KVMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMSS TEDKAYEIMRELDVNYVLVIFGGLTGYSSDDINKFLWMVRIGGSTDRGAHIKENDYYTPQ GEFRVDKEGSPVLLNCLMYKMCYYRFGSVYTESGKPTGYDRVRNVEIGNKDFELDVLEEA YTTEHWLVRIYKVKDLRNRGNKMNVRPLLRLILGRFFGQFSRFTTMCVQHICSPVDNARR KVEHIYTGPLETALADAMFKCDPEGPLMVHTTKLYPSLDATSFHVLGRVMSGTLSADQNV RILGENYSLEDEEDSRQGVVSKLWISEARYNIQVTRVSAGNWVLIEGVDQPIVKTSTITD IGDNKQAHIFRPFKFNTTSVMKIAVEPVNPSELPKMLDGLRKINKSYPLVTTKVEESGEH IILGTGELYLDCIMYDLRKMYSEIDIKVADPVVSFCETVVETSSLKCFAETPNKKNKLTM IAEPLEKGLAEDIENEVVQIWWPKKRLGEFFQNKYDWDLLASRSIWAFGPDSTGPNILVD DTLPSEVDKSLLSSVKDSIVQGFQWGTREGPLCDEPIRNVKFKILDAQIASEPIQRGGGQ VIPTARRVAYSAFLLATPRLMEPYLFVEVLAPADCISAVYTVLARRRGHVTQDAPVPGSP LYTIKAFLPAIDSFGFETDLRLHTQGQALCLSVFHHWQIVPGDPLDKGIVIRPLEPQPLT HLAREFMIKTRRRKGLSEDVSINKFFDDPMLLELAKQNVMLSYGMQETFSLFDNKGDGKI SYLQLGEVLRAMGQNPTDAEVKKCKEPESRITFETFLPILLTISKNKETPRVDDFIEGFR VFDKDQNGTIHSAELRHLLTNLGEKLTDEEVNELLQGHEDAQGNVNYEEFIKSVIFGMNS FTFNLDNGFLEGIVRGFKAGILKRPDYINLTQCENIDDLKQHLQSTDYGDFLNNEQGPLT VLAIDSXLTEKLVIEFNYLRNNSLQPLSQFLEYITYGYM--------------------- ----------------------ELYDAILVDTPLAHYFGECLSHKDLDELNIEIIRNTLY KAYIDDFYNFCKGLGSATEEIMCEILGFEADRRAFIITINSFETDLSTDDRKKLYSKCGR LHPDDLETLSKAEDIEQVKDVSQKYSEYNFIFKDYGSAGDAKSLEDRFFEKEV------- ------------------------------------------------------------ ---------------------------LGPCVYLWDATSGEIKSLMDMEQDDQYISSVAW VKNGTHLAIGTSTNDVQLWDVQNQKKLRSMQGHIARVGALSWNDHILTSGSRSGFINHHD VRVREHLV-SSFNAHSQEVCGLRWSPDGKHLASGGNDNVLNIFSNQFERPIYSFTEHSAA VKALAWCPWQPNLLASGGGSADQHIRFWNCNIGSNLNNVNTRSQVCSLLWSSEYKELISS HGYEFNQLTIWSYPKMEIVTELTGHANRVLHMAMSPDGSVVVSAGADETLRLWKCF---- ------------------------------------------------ANLGIGLSISXS VVGAAWGILTTGSSIIGGGVKAPRIRTKNLVSIIFCEAVAIYGIILAIVISNYNNHYAGY AMFGAGLTVGFSNLFCGICVGIVGSGAALADAQNASLFVKILVVEIFGSAIGLFGVIVAI LQIQKIKMGDKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGASDTYPQQCSALRKNGFVVLKGKACK IVDMTTSKTGKHGHAKVHLVGLDIFSGKKCEDICPSTHNMQVPNVSRKEYEVIDLSENFF SLMSEDGDTRDDLKLSATVWKAMSEEVVKDLKIGKGKLAGPKGVSIDKQGRVVIVDNRSS TVWLYTLNGKILGKFGARGHARLAGPHFCSIDPDGDVVVTDFHNHRVKVFSEGQYKFSFG SAGDGNGQFNAPTGICVDKQGNILVADWGNSRIQIFDKYGSFLSHIDLYGPQGLAITADN SVIVADSGNHCLKVYKHLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXKVEVRKTVNPLFEKRPKNFGIGQDIQPKRDLSRFVRWPKY IRLQRAKRVLYQRLKVPPPINQFTQALDRQNATQLFRLMDKYRPETKEEKKVKRIEEAKK KVAGETVEPAKRLPMMRSGINTVTALVERKKTDLVVIANDVDPIEIVLFLPALCRKMGVP YCIVLGRVVHRKTATCLAFPQVNTEDRSALSKLVETVRTNFNERAEEIRKNWGGGVMGLK SQARITKLEKAKAKELAQRMRYLSAYLLALMGGNDSPSVDDVNKILSSVGVDCDKALAQK VVDQLSGKNIQELIAAGKEKLASVPSGGAVASQEAKKEEEEDGDMGFGLFDMVIEKVHAR QIFDSRGNPTVEVDLTTDKGLFRAAVPSGASTGIYEALELRDKG-KDYHGKSVLKAIENV NSIIAPALVIDVTDQTAVDEMLLKLDGTENKSKLGANAILGVSLAVCQAGAKHKGVPLYR HIADLAGNKELILPVPAFNVINGGSHAGNKLAMQEFMLLPTGATSFTEAMRMGSETYHHL KNVIKAKYGQDACNVGDEGGFAPNIQNNEEGLELLKTAIEKAGYTGKIEIGMDVAASEFY KKYDLDFKNPESDASKWLSSEQLFDVYKGFIENYPVVSIEDAFDQDDWEAWTNMNGIQLV GDDLTVTNPKRVKEAIDKKACNCLLLKVNQIGSVTESIEACKLAQQAGWGVMVSHRSGET EDTFIADLVVGLNTGQIKTGAPCRSERLAKYNQLLRIEEELGDSAKFAGKNFRHPXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX-----------------RIKIEKDTKVPNACIFTILKEDSTLG GLLMDQLCKDPGVLFAGYKVPHPLDHKIILRVQTTPEYSPQEAFTNAITDLISEISLIEE RF-----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXMGCSMSAEDRLAVERNKQIEKSLREDGQQAAKDIKLLLLGAGESGK STIVKQMKIIHEGGFTSEDNKQFKPVVYSNTIQSLVAIIRAMSILHIEFGDPERESDAKL VLDVIQRMEDTEPFTDELLAAMKRLWSDSGVQECFNRSNEYQLNDSAKYFLDDIDRLGSK DYMPTEQDILRTRVKTTGIVEVHFNFKNLNFK---------------------------- ------------------------------------------------------------ ---------------------------------------------------------YHS QFTNAPQVVGNMALLPLRTQFKGPAMDVIDEALLYFKANVFFRNYEIKSEADRTLIYLTL YISECLKKLQKCRSKNEGLKEMQTLAIARFSLPGEAQFPLNAMYTKPSNRNEEDNMRAYI QQLRQETGLRLCDRVFD-ESDKPSKWWMCFVKRKFMDKSLSGPGQXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX-KFAAVSVLREGACKGVVHFHQDSNTTIKGEITGLTPGKHGFH VHEFGDNTNGCMSAGAHYNPSSKTHGGPEDAERHVGDLGNVVAGKFEIKDKLITLNGPQT VVGRTLVIHADEDDLGKGGHEDSKTTGHAGARVACGVIGLAK------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------RIMGPNYTHVKSIQRTILMMGRYTEPIEDVPCGNVCGLVGVDQFLVKTGTIT TFENAHNLRVMKFSVSPVVRVAVECKNPADLPKLVEGLKRLSKSDPLVQISIEESGEHII AGAGELHLEICLKDLEEDHACVPIKVSDPVVSYRETVSEESDRMCLSKSPNKHNRLYMKA RPMPDGLPADIDNGKVTQRQELKERARYLAETYDYDITEARKIWCFGPETTGPNIVVDCT KGVQYLNEIKDSVVAGFQWASKEGVLCDEHMRGVRFDIHDVTLHTDTIHRGGGQIIPTAR RCFYASVLTAAPRLLEPVYLVEIQSPEAVVGGIYGVLNRRRGHVFEENRVVGTPMFVVKA YLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILVVGDIRKRKGLSPTIPPLDNFLDKLX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXSEIKIANPPGDCISSLAFGPSQSQFLLASSWDCSVRLYDVNENALRFSHQHSMPVLD SCFQDSVQVLSGGLDKTLKLFNCNTTAETVIGKHDGAIKCVEHCPELNAILTGSWDSTVK MWDIRTPNHVGSFSQADKVYTMSLCGDKLLVATAGRKVLMWDLRYTGYVQQKRESSLRYQ TRCIKSFPDKQGYVLSSIEGRVAVEYLDPSPDVQKRKYAFKCHRVKEGNVEKIYPVNALA FHSIHSTFASGGFDGYVNIWDGFNKKRLCQFHKYPTSITALSFDGSGTMLAIASSYMFED DHSEDAIYIRRVTDHETKPK---------------------------------------- ------------------------------AHTQGKKHQANLAQRAAKDAKESPSQPAPL KQRVAVREFVKIGRPGYKVTKQQDPETGQYSLLCQIDYPEIAEGVIPMHRFMSAYEQRID PPDRKYQYVLFAAEPYETIAFKVPSKEVDKEAKTFWTLWNKETKQFFLQFAFKSETPLMP PRSSGMLGPPPMMDDEVELERLWKVRRTLMQLCHDRMYLVTQGELDMTLDQFKQLYGD-- TSKCQLRTSLTFLVAHNDDPTDQLFVFFPEDERVGIKIIKTYCQKMQEENISRAIIVVRQ AMTPSARQALQDMAPKYILEMFFESELLVNVTEHQLVPEHVVLTQDEKRELLQRYKLKES QLPRIQSGDAIARYFGLTKGQVVKIVRPSETAGRYVSYRLVV------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------LTLGIETVGGVMTKLIPRNTVIPTKKSQIFSTAADQQPT VSIQVYEGERPMTKDNHLLGKFDLTGIPPAPRGVPQIEVTFEIDVNGI------------ ------------------------XEKFAEEDKKVKEKVEARNELEGYAYSLKNQIGDKE KLGGKLSADDKDTIEKAVDEQIKWLEKNHDAEIEEFKEHKKQLEEIAQPIVSKIYQAAPP TE-DSEKDELESMQDDPELEVIKARVKEMEEEAEKIKEMQNEVEKQYSVEEKLDADTRSV WIGNVDYGATAEELEAHFHGCGSVNRVTIMCDKYTGHPKGFAYVEFADKDAVNTAMALDE SLFRGRQIKVTCKRTNRPGISTTNRPPRARYMRPRYGYIYATHVPRFR--GRFRPRKSFH YSPYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXPKIGINGFGRIGRLVARVAFEHVDVVAINDPFIDLEYMVYMFKYDSTHGP FKGEVSLIINGHKVSVHNSKDPAAIPWSEDGAEYVVESTGCFTTVEKASAHLKGGAKKVV ISAPSADAPMFVMGVNEKEYKKEYNVISNASCTTNCLAPLAKVINDRFTIIEGLMTTVHS YTATQKTVDGPSNKDWRGGRTAAQNIIPSSTGAAKAVGKVIPVLNGKLTGMSFRVPTPNV SVVDLTCRLEKAAKYDDIKKVVKGPLKGILGYTEDQVVSSDFNTSSYSSVFDAGAGISLN DHFVKLVSWYDNEYGYSNRVVDLINYVYKVD----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----ESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQ RAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDTTGRLEILRIHTKNMKLAKDVDLE RVAAETHGHVGSDLAALCSEAALQQIREKMDLIDLEDEAIDAEVLNALAVSQEDFRWALS KSNPSALRETAVEVPNVSWDDVGGLENVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFY GPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVRDIFDKARAAAPCVLFFD ELDSIAKARGGSVGDAGGAADRVINQLLTEMDGMSSKKNVFIIGATNRPDIIDSAILRPG RLDQLIYIPLPDDKSRVAILKANLRKSPVAKDVDVDYLAKVTHGFSGADLTEICQRACKL AIREAIESDIRREKENADRGDDYDPVPEIRRDHFEEAMKFARRSVTDNDIRKYEMFAQTL QQSRGIGP----MFGTSLSAGNMFSSNPVKDLEIPSPPDDSISSMAFSPGSLPNTFLAAG SWDNSVRCWEVQQNGTVVPKAWQSHAGPILDVNWNDDGTKIFTASTDKSAKMWDLNANQS IQVAQHEAPVKTVHWIKGASYTCLMTGSWDKTLKFWDLRTPNPILTLQLPERVYCADVVY PMAVVGTAGRHVVIYQLDNQPQEYKRMESPLKYQHRCVSIFTERKTGQPVGFALGSIEGR AAIQYVNPVNPKDNFTFKCHRANQQDIYAVNSIAFHPVHGTLATVGSDGRFSFWDKDART KLKTSEPLDQPITCCSFNAQGNIFAYSSSYDWSKGHEGYDPSKMKPHIFLRSCFEELKQT QKKMSSPSPGKRRMDTDVVKLIESKHEVTLLGGLHEFVVKFYGPSGTPYEGGIWKVRVDL PERYPFKSPSIGFVNKIFHPNVDEVSGTVCLDVINQAWTALYDLSNIFESFLPQLLTYPN PTDPLNGSAAALYLHRPEEYNKKVQEYVRKYATEAALREQESSLSDFSDDEMDGMELMEE GDILTTLKILIIGESGVGKSSLLLRFCENTFDPDQAATIGVDFKVRTITVDGNKAKLAIW DTAGQERFRTLTPSYYRGAQGCILVYDISNKNSFSKLENWLSELETYSTKHEIVKMLVGN KID-ENREVSRDEGLKFARKHHMLFIEASAKTKEGVQCAFEELVEKIIQTPGLWETDGFS LSPVVWGVINSGHCSFRMPSKTEKFCKNKYNLTGLCNRKSCSLANSNYATIREEEGICYL YMKTIERAPFPNRLWEKVKLSRNYEKARKQIDENLIYWPRFYIQKCKQRHTKILQYLSRM RKLTLKRQKKIVPLSKKVERREARREEKALTVARIDNVIQKELEERLKSGKYGNIHSFPQ KAYNQAMEELDVE-------EREYV--EDFEESDLSDMEAAQARFAAGEKLKTFKVYRWD PDKPGDKPHMQTYQVDLNDCGPMVLDALIKIKNEIDPTLAFRRSCREGICGSCSMNINGA NTLACLCKIDENVSKTSRIYPLPHMWVVKDLVPDMNNFYAQYKYIEPYLKKKNFDDKDIG KKSFLQSPVDRAKLDGMIDCILCACCSTSCPSYWWNGDKYLGPAVIMQAYRWIMDSRDDF KHERLAQMRDEWSLYRCHTIMNCTKTCPKGLNPGAAIGEMKKVMLGYSSDGIPKQXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXMDSKGNKVVVCDNGTGFVKRGFSGTNFPTHIFPSLVGRPILRS KAKIGNIELKDLMIGDEASELRSLLEVSYPMENGIVRNWDDMISLYKYTFGPDKLNIDPS HCKLLLTEPPMNPIKNREKMVEVMFEQFNFHALYIAIQAVLTLYAQGLLTGVVVDSGDGV THICPVFDGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRIMKEKLCYV GYDIELEQKLALETTVLVEQYTLPDGRVIKVGGERFEAPEALFQPHLINVEGVGIAELLF NTIQAADIDTRADFYKHIVLSGGSTMYPGLPSRLEREMKQLYLERVLKGDTERLAKFKIR IEDPPRRKHMVFMGGAVLAQIMKDKEDFWMSKKEYQEQGVRVLSKLGVS----------- ----AWSPKAPLKLQTIFVSPPKEGEVRIKVLYTGVCHTDAYTLEGHDPEGVFPVILGHE GAGVVQSVGDGVTEFQPGDHVIPLYIPQCRTCKFCMSSKTNLCQKIRETQGKGVMPDGTS RFKCDDKEIFHFMGCSTFSEYTVVAAIYLCKVDKAADLQKVCLLGCGISTGYGAVLNNAK VEPGSTCGVWGMGAVGLAAVVGCKKAGAKIIYAIDINPKKFELAKRLGATDVLNPNDFDK PIQQVLIEKTEGGFDYTFECIGNVQTMRAALESCHKGWGTSVVIGVAASGQEISTRPFQL VTGRTWKGSAFGGWKSKDSVPKLVDEYLDNSLALDEFITHTMDLDDVNTAFDLMLSGES- ---TVLANQPLVIDNGSGIIKAGFAGDQQPKCKFPNYVGRPKHIRVMAGALEGELFIGPK AEEHRGLLSIKYPMEHGIITEWNDMEKIWDYIYSKEQLHTFSEEHPVLLTEAPLNPRRNR ERAAEIFFETFNVPALYISLQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGYAMPHSII RSDIAGRDVSKYLRLLLRKEGYDFHTTAEFEIVKGLKENVCYLATSPLK-------KVQY QLPDGQVMXVGSSKYRAPELLFRPDLVGEEYPGIHEVLTSAIQRSDIDLRKMLYSNVVLS GGSTMFKGFGDRLLNEMRQLAPKNTKIRISAPLERLISTWIGGSILASLDTFKKIWVSKK EYDNDGAKIIHRKTF--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------TSIGTLSQRITNQLMGLKGLVSQLKEIHSYLDNVANGRLPINHQI IYMLQDVFNLLPEVNLQSFVRSVFVTTNDQLLVGYISALIRSVIALHNLINNKVQNRDSE KGEGSKDAMGLLLAKFWSLFGSEEHKVIIVGLDNAGKTTILYQFLMNEVVQTSPTIGSNV EEVVWKNIHFIMWDIGGQESLRASWSTYYTNTEFVILVIDSTDRERLSITKEELYRMLAC EELKKASLLVYANKQDLKGAMSAAEISHQLNLTSIKEQGWHIQGCCALTGEGLYQGLDWI GNRIKRKVIPIRRVPFTDHSQLPPDYSATPGGTLFSTTPGGTRIIYDRNFLMQCRNSPLA RTPPANLPDIPGVTRPPPPGKRKEIYKYEAPWTVYSMNWSVRPDRRFRLALGSFIEEYNN KVQIVSLDEETSDFICPHTFDHPYPTTKIMWIPDTKGTCPDLLATSGDYLRVWRVTRLEC LLNNNKNSDFCAPLTSFDWNEVDPNLLGTSSIDTTCTIWGLETGQAVGVVQGHVKTQLIA HDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDSQHLPLLRLAWNKQ DPNYLATMAMDALEVIILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQAL IWDIQQMPRAIEDPILAYTAAGEINQIQWSSTQPDWIAICYNNCLEILRVRSLSSSSKVA VLGASGGIGQPLSLLLKLNPLVSHLSLYDIVHTPGVAADLSHCSTNAIVTGHNGPDQLRE ALTGCDLVTIPAGVPRKPGMTRDDLFNTNASIVRDLADACAKYCPKAMICVISNPINSTV PIVSEVFKMRNVYDPKRIFGVTTLDIVRANTFIAQAKGLDVAHFNCHVIGGHSGITIIPL ISQCNPPVNFPXEEKVTLTTRIXNAGTEVVEAKAGAGS---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------NLLKERNYNNYSWQDLV ANGVVEYLDTMEEETSTVAMTPDELAAKGQSYCSSYTHCEIHPSMILGVCASIIPFPDHN QSPRNTYQSAMGKQAMGVYITNYHVRMDTLAHVLFYP----------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------DVSDPYPVHVCDFCGLIAIANLRNQNFEC RGCRNKTQVSQIQMPYACKLLFQELMGMSITPRMMMLLDEIPGGFSFDNCKRNAALAQGF KQPKALKTGTTIAGIIFKDGVVLGADTRATSDTIVADKNCSKIHRIASNIYCCGAGTAAD TEMTTRMIESNLELMRLNMGRTPRVVAANRMLKQFLFRYQGHISAALVLGGVDHTGPYLT CVLPHGSTDSLPYVTMGSGSLAAMAVFESRYKLNMEKQEAMQLVHDAIAAGIFNDLGSGS NVDLCVITKNVEFLRPFNVTTKKGVKQGEYKYAKGTTVVLSETVEILEEDILXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGLLTFIKKLKQKEREV-LI MLGLDNAGKTTIFKKFNGEDISTISPTVGFSIKTLEHRGFKLNLWDVGGQKSLRSYWRNY FESTDGLVWVVDSADRRRLEDCKAELDSLLVEERLAGATLLIFANKQDLEGAVSAEIIKE LLDGDNLKTHHGMILGCSSVTGENLLQGMDWLIKDISSRIFTLD---------------- ------------------------------------------------------------ -----------------------------------------------TDIAINWSGGLHH AKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTMSFHKY GEYFPGTGDLRDIGAGKGKYYAVNFPLRDGINDESYEQVFQPVMSKVMEMFQPSAIVLQC GADSLSGDRLGCFNLSLKGHGKCVEFVRKFNMPTLMVGGGGYTIRNVARCWTYETSIALN CEIANELPYNDYFEYYGPDFRLHINPSNMANQNTPEYLEKVKTRLFENLRMLPHAPGVQM QDIPEDAIKEEQNPDERVS------------------------------------XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXESDEEFDKRYESFFNDPNIDDWTIRKRMNDL HGYDLVPEPKIIIAAMKACRRLNDYALAVRYLEAIKDKCGPHVGKIWPYLLTEIGPTLKE LGILTPEEMGYDKPELACKDVFEMVVRLRGLPWTTGSEDIIQFLEGCSI----NDVHFIY TKEGKPSGEAYVELNSEDDFNLALTKNQQYLGKRYIDVFAANSEEMEWAVKKSGVNPDAV VRLRGLPFSCDRENLLKFFDGLPVTPNGVSLMTDPMGNATGEAFVQFANQSVADAALNKH MERIVHRYIEI------------------------------------------------- ---------------------------------------YKDKDKPTQIRFSNITAAKAV ADAIRTSLGPRGMDKMIQSGKGDVTITNDGATILKQMEVLHPAAKMLVELSKAQDVEAGD GTTTVVVVAGSLLDAAQKLLEKGIHPTAISESFQSAAAKSCAILEEMAMPLELADRESLL KSATTSLNSKVVSQYSGVLSPICVDAVLRVIDPSKDTNVDLHDIKLIQKLGGTVEDTELI DGLVFNQKTAGQGGPNRIEKAKIGLIQFCISPPKTDMENQVIVSDYTQMDRVLREERQYI LNIIKQIKKAGCNVLLIQKSILRDAVNDLALHFLAKMKILVVKDIEREDIEFVCKTIGCR PIASLDHFQPEMLGTADLVEEIQAGDSKLVKVSGIQNAGKTVTVLVRGSNKLVLEEAERS IHDALCVIRCLVKKRALIAGGGAPEIELSLRLMELSETLTGMEQYCFRAFAEALEVVPFT LAENAGLNPIATVTELRNRHARGEKMSGINVRKGAITNILEENVVQPLLVSTSAIHLAAE TVRSILKIDDIVAC-MILLEINNKIIEETLSLKFNNSLAGNKPEHIDVTVADFDGVLYHI SNPNGDKTKMMVSISLKFYKDLQEHGADSLIKREYGPWLTTPEKGYNVSLLFDNNLPADR DEAVKKAGLLKRNCFASVFEKYFDFQQKEKRAVINYRDDETMYVEAKKDRVTVIFSTVFK DIDDIIIGKVFMQEFKEGRRQYQQAPQVLFSHKEPPLELQNTSAKTGENIGYITFVLFPR HSARDNTINLIHTLRNYLHYHIKCSKAYIHARMRTKTNDFLKVLNRARPEPKAAEKKIMX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKTKFGPLKDEDRIF TNLYGRHDWRLKGAMKRGDWYKTKEIILKGFEWIQNEVKKSGLRGRGGAGFPTGMKWSFM NKPNDGRPRYLVVNGDEGEPGTCKDREILRHDPHKLIEGCLIAGSAIGARAAYIYIRGEF YNEASNTQMAIREAYEAGLIGKNACGSGYDFDVFLHRGAGAYVCGEETALIESIEGXPGK PRLKPPFPADIGLFG---------------------------------KEVMMDFDDLTD KQSAFGTAAIIVLDKSADVVKCIARLAHFYKHESCGQCTPCREGCNWMSKVMDRFAVGKA RPEEIDMLYEMSKQIEGHTICALADGAAWPVQGLIRHYRPEIEQRMKEYAEKT------- ------------------------------------------------------------ -------VAVRAIPELIALLNDDDQVVVGHAALMSNQLSKKEASRHAILNSPQMIAALIN ALNKTTDPETIGLLTGTLHNLSHHAQGLLYIFKSGGIPALVRLLSSPIESVLFYAITTLH NLLLHQEGAKLAVHSAGGLQKMVLLLGYPAPKFLAITTDCLQILAYGNQECKLIILASRG PQQLVGIMETHNY-KLLWTTSRVLKVLSVCPSSKVAIVEAGGVGALGKHLNHSSERLIQN CMWTIRNLSDVATKVEGVEGILETSVQXLSSHDNDMVICSAGILSHLTCNNHVNKMAV-- ------------------------------------------------------------ -----------------------NPQLRELGAVPRIVQLLIRAHQELQKADGVVVDGVRM EEVVEGCVGALHILSRDVYNRTIIKELNCIPLFXQLLYSPLENTQRVAAGVLCELAAEKD AVDATEQEGATAPLTELLHSRNEAVATYAAAILFRMSENKSPDYRKRLSIELTNSLVRGD PMSADLQWLIIRNNSXFLMKRKAFSKERNNLKGINSFRYNGLVNRKTVGVEEGADGKGVT LITKSSARKPAKLYRKVELKKNARKTFKSIKSIVEKGNYRKDLKMAAIRRASAILRSQKP VVPKKVKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------- ----------------------------------QKCVAMCMDRYMDTWNLVSRAYTQRL QKEKNRLMNRLFGSSKPKQPPPNMSDCVTSLDTRGESVDKKXARLDQELAKYRDQMKKMR EGPSKNLLKQKAVRILKQKRMFEQQRDNLMQQSFNLEQANYNIQSLKDTQVAVNAMKSGV KEFKKEFKKINVNAIEDLQDQMEDLTEQSNEIQEIMGRSYGMPEIDEDELEAELEALGDE IALDDDSSYLDEASRAPNAPTSVPGSESVVNKDGIPVDEFGLPKIPAQVTPINPPTPASP QLQNIVCTVNLGCRLDLKKIAMHARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTG AKSEEFARLAARKYARIVQKLGFQAKFLDFKIQNMVGSCDVKFPIRLEGLVLMHSQFSSY EPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKERSEINEAFENIYPILKGFKKQXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGFAPR GGGRG----GRGGGGRGGFGGRGGG--GRGGGMSGGSKVIVTPHRLPGMFVLRGKTDTLL TKNLVVGESVYGEKRVSADLEQKVEYREWNPFRSKLGAAILTGIGDIHIKPGSHVLYLGA SNGTTCSHVADLVGPEGMVYAVEFSLRCALKLKEMTSRRKNIVPIIEDARHPWKYRMLVG IVDTVFADVAQPDQARIVALNSDMFLKNGGYAVMAIKASCIDSTAPPQTVFAQESEKLVA AEFKRKELLTLEPYERDHAILVAQYKP-------DKASDLLSKIGKNGKGAGAGLGLLAA AGGLAYGLSKSFYTVEGGQRAIIFSRVGGIQPDIYKEGLHFRVPWLQYPIIYDIRARPRK ISSPTGSKDLQMVNISLRVLSRPDPAQLPTMYRQLGTDYDERVLPSICNEVLKSVVAKFN ASQLITQRQQVSLLVRKELTDRARDFNIILDDVAITELAFGREYTAAVEAKQIAQQEAQR AQYIVEKAKQERQQKVVQAEGESKAAKLIGEAISKNPGYLKLKKIRAAQNIAKTVSQSKN RVYAQAGTLMLNVNDKEFDENLE-----------------------------------SF GRREIEIAEQEMPGLMSLRKKGQGDKPLVGARIIGCTHVTAQTAVLIETLAALGAQVRWC ACNIYSTQNEVAAALAEAGFSVFAWKGESEADFWWCIDKCIQSDNWQPNMILDDGGDATH LILKKYPATFGRIKGIVEESVTGVHRLYQLSKSGKLTVPAMNVNDSVTKTKFDNLYSCKE SVLDALKRTTDIMLGGKQVLVCGYGEVGKGCC---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------PDPDT IKMFMGQISKSLDEDNLKAYLSEFGQVYEVKIIRDK-TGTSRGCAFVTFYTRKDALTAQM ALHNLKTMPGLIHPIQMTPADGPSLKVEDRRLFIGKVQKTLTEDELREAFAPFGEIENLY IVREMNDPKKGCAFVTYAKKESAINAINNLHMTKVFKTSTEATVVKIADTQKEKXRKRNL NNLQNGQLQFIAGGFGGVCLVVTGHPFDTVKVRLQTAPK-YSGTYDCVKQIFIKEGPKGF YKGMATPLIFALSFFGYHI-GKRLQLAGTFSSFILGPGERIKCLLQVCAKQLFKEGGVRS IFKGTMATFLRDVPASGIYFMTYDWIRISLTPNGQ--KDLSTRTLFAGGMAGIFNWIVAM PPDVLKSRLQTREEGAAALFKGFVPVMLRAFPANAACFLGYELT-----SGSSSFQRLSQ DISNNIYKISSNVSQLQSIQKQLLSGKTDAELKSKFHDLQHYTHQLATETSSKMKELTNY DVDQRTHKFQKEQLLNEFSKVLNTFQTIQRQEKDLEKKAISEVDLEILRERDDALVKLES DISDVNQIFKDLSVLVHEQGEVIDTIEDNVVSVQVEQGTEELQKARKHQTSARKKKLIIF IIILVIIIIIAIILGVKLKMVQVQIGLLVECDSTITELIIKIDESRELGESFIMADLDEN HLFITPEVIQALLDKLGEFADSLHF------------QEAIQRLRETEEMLQKKSDFLEK KIEQEISTARKRAAIQALKRKKRYEKQLQQIDGTLSTIEFQREALENASTNTEVLRVMGD AAKALKSAHSHMNVDDVHNLMDDVAEQQEIANEISNAISNPVGFGQDVDEDDLLAELEEL EQEALDEELIKV-SLPAVPSQ-DADMKELEMWAS-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------DNPSWDNEKTIIITCSHGTAACXMIVYKLTPSGLEWGRQNKDTGN NPRGYQPSHYEKVQMLLSDRFLGYFETPFQSSWNYNFMGVNHNPNMKYDLQIANPKPFYD PIHRPSHFLNFNALEDSCDQEDFF------------------------GKQGTFHSQQAI DYGTKMVGGVSPGKGGKMHLGLPVFNSVKEAKEATNCDATVIYVPPPVAAAACLEAIDAE VPLIVMITEGIPQHDMVRVKRRLMEQDKCRLVGPNCPGLIKPGECKIGIMPGHIHTAGKI GVVSRSGTLTYEAVHQTTLTGLGQTICVGIGGDPFNGTNFIDCLDVFIKDPSTEGIILIG EIGGQAEEQASDFLKEHNXPN--------------------------------------- ----------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------IVERAEMKLRLDNIVI QQGRLVDQNSNKEMLSMIRHGADHVFASKDSEITDENIDALLERGEKKTEEMQKKLSQLG EGTLRTFTMDQTE-SVYQFEGEDYREKQKISGIGHWIEPPKRERKANYAVDAYFREALRV TEPKAPKAPRPPKQPVVQDFQFYPPQLFELLDKEIYFFRKSIGYKVPKDPDHGADAEKIR KEEQRKIDEAEPLTDEEIAIKEDLLKGFSNWNKRDFNQFIKANEKYGRNDLESISKDVEG KAPEEVVEYATVFWERCNELQDIERHMAQIERGEHKIQRKLGIKKALDVKMSRYKAPFHQ LRIAYGTNKGKNYTEEEDRFLVCMLHRLGIDKENVYEQLRTSVRQAPHFRFDWFLKSRTA MELQRRCHSLITLIERENVEIEEKEKADRGKDTKPSWAEQVELGDDDVLPPPSEVFDKKT GLKTVVEYKINEDGKKVKVIKTYKVETCKVSRTVARRKLWKKFGEVQNDPAGPNPASTKE DTSITYIHSKELQDDDPLSKLKVMCRICKGDHWTTKCPYKDSLVPLQESNQKPGKYIPPS MREGGNKKGESMSMDDAATIRVTNLSEDTRESDLQELFRPFGLISRIFLVE--------- -------------------------------------MTETYDFLFKFLIIGSAGTGKSC LLHQFIENKFRQDSSHTIGVEFGSKVVNVGGKFVKLQIWDTAGQERFRSVTRSYYRGAAG ALLVYDVTSRESFNALANWLSDARTLSSPNIVIVLVGNKKDLENEREVTFLEASRFAQEN DLMFLETSALTSENVEETFLKCARNILAKIESGEMDPERLGSGIQYGNASLRRLQQQSHH CACXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------ ------------------------------------------------------------ -------------------------------------------LAKMEKILEVKLRGKEK GQPVNPKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXSAATARIQPKKQTLDDAYAPPANFLEIDVMNPEGKKRYTDYEIRMKTN LPVFKIKESTVRRXYSDFDWLASELERDSKIVVPVLPGKAWGRQLPFRSDDGLFDAEFIE ERRRGLEIFINKVAGHPLAQNEKCLHMFLLEPTIDKNYVPGKVRTTXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMALSKSGNLYNRQNWEESDFPILCQTCLG DNPYLRMTREKYGKECKICARPFTVFRWCPGKGMRFKKTEICQSCCRMKNVCQTCLLDLE YGLPVQVRDAALNIQDEMPKSDVGREFHVQKLEKELANTDGTMPHGTLGKVRGTSDMLAK LARTAPYYKRNRPHICSFWVKEACKTGEECPYRHEKPTDPDDPLADQNIKD--------- -------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLDDYMKIEKIG EGTYGVVYKGKHKKTGRLVALKKIRLDSEDEGVPATAIREISVLKELIHPGIVTLEEVLM QEGKLYLVFEYLTMDLKKYFDTLPTEKLMDPVLMKSYMYQILEAMLFCHKRRIIHRDLKP QNLLIDSKGMIKLADFGLARAVCIPVRAYTHEIVTLWYRAPEVLLGSPRYCPAVDLWSIG CIFAEMASKRPIFRGDSEIDQLFRIFRTLSTPTEETWPGVSSLPDYKSTFPSWRSNNLHI AATGDALDLLQAMFVYNPTYRISAAKALQHKYFAGKIFSAIGKLGVGLAVAGSLASSALY NVDGGHRAVIFDRFAGVRQQVVGEGTHFIIPWVQKPIIFDIRSKPRSVPTITGSKDLQNV NITLRILFRPLAERLPQIFTSLGSDYDERVLPSIVNEVLKAVVAQYDASELITQREVVSQ KVNEELTNRAAQFGIILDDISLTHLTFGREFTEAVEMKQVAQQDAERARYIVEKEEQLKL AAIIRAEGDSIAADLLAKAFAESGEGLVELRKIEAAEDIAAQLSQSPNVTYLPQGQQTLL SLPMKTINQKQFVKIPDGVQLSIKSRKVIVKGPRGTLRRDFSHMAVDLQKASANQVIVEK WFGTRKELAGVKTVCTHIENMIKGVTKGYKYKMRSVYAHFPINVSISDANTLVEIRNFLG EKHNRQVRMLPGVTCIASKDMKDEFVLEGNDIELVSRSAALIQQSTSVKDKDIRKFLDGI YVSEKLHVVEDMGCFHSKDEKVASLRSKQIDLKLKNDQALASRQVKLLLLGAGESGKSTF VKQIKIIHENGYSDEECLSYKPVVHNNTVQSLVAIIHAMGQLKIAFSSQDCTKEARQMFH MISGMEDVLLTPELGQVMRKLWKDSGVQKCFQRSREYQLNDSAEYFLNSLERISQMNYKP TPQDVLRTRVKTTGIVETHFTLKGLNFKLVDIGGQRSERKKWIHCFEGVTAIIFLVALSE YDLSLAEDQEMNRMMESMRLFDSICNNRWFKETSMILFLNKKDLFEMKIRTSPLSVCFPE YRGXNTYEEASTFIR--------------------------------------------- --XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXX---------YLVYRYLLESGFSHAAYTFGVESHISHSNINGSIVPPAAL LNIIQKGLQYTEAEISIAEDGTERQIETLSLIDAVLPEVIEQRKQMAAKGGAEES-QEPM DIDSGIEIPSSKVAVLKGHESEVFICAWNPINDLLASGSGDSTARIWNMNDPLSANQLVL RHCIQKGGTEVPSNKDVT------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------QAHS KEIYTFKGSPTGAGSKNPNANLILASASFDSTVIFWDVERGTCFPKIS-HLEPVFRVAFS PDAKYIASGSFDKGVHFWGVQRGALVHIYRGPGGIFEVCWNPRGDKVGGFAFEGSVFVLD LRKSSSDLASLFECPVCFDYALPPIMQCQSGHIVCSHCRPKLQFCPTCRGALGNIRNLAM EKVASQVLFPCRYFSNGCEVTLPHTEKTGHEDGCEFRPYNCPCPGASCKWQGSLEQVMPH LLQQHKSITTLQGEDIVFLATDINLPGAVDWVMMQTCFGHHFMLVLEKQEKSEGNQLFYT IVQLIGTRKQAESFAYRLELNGQKRRLTWEATPRSIHDGVQSAINSSDCLVFDTNVARLF ADNGNLSINVTINMCMAYQSFQQEYMEIPIVTRVYTTACVLTTVAVQLDIVSPFQLYFNP DLIVKNLQVWRLITNFMFFGSLGFNFFFNIIFTYRYCRMLEEGSFRSRTADFVFMFLFGG LLTSVVVNLVFLGHSFTIMLVYVWSRRNPYIRMNFLGLLNFQAPYLPWVLLGFSLLLGXS IAVDLMGIAVGHIYFFLEDVFPNQPGGFRILKTPQILKWLFDAP---------------- -----------IRADERKQVETRAIVGKLGVLKKANGSAYVEQGKTKVLIGIYGPQEVYE LKNQQGKMLINCQCSMAPFSLLDKK----CETKVVEFARILKQIFESAIISQCYINSQID IFLQILEHDGSALASSINATTLALVDAGIKLKGLVCSSSCGSVKGKALVDLNNLEEQQSF MLTVAMLPSVDQILMHSLKGKLHESQFDEVTETAAKACKDVLNNMNE-----------VI VGHNDNPIFEIEFLTPAKATDPKREDHKHLNQFIAHAALDLVDEQLWTTNNMYLKVVDKF NEWHVSAFVTASKFRFLLLHDVKNEDSIKNFFQDVYEMFIKHSMNLFYKFNTPIKTSAFE RKVQFFGKRHLEGQVRLAHTDIQVPDFSDYRHEKV-DKRKAVTGLAIAAAAIPGTYIAKT VVHDVVLSLSASADVLAIGKIEVDLSKIPEGKNVTFKWRGQPLFVRHRTAEEIAAEQTVD VSTLRDPQHDNDRVKKPEWLIVVGICTHLGCVPLPNQGEFGGYYCPCHGSHYDFSGRIRK GPAPLNLSVPKHNFTEENTIIVGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXENVKAFLAQAREDFNQKWENPQQNTASLDDFDRIKTL GTGSFGRVMLVQHKATKEFYAMKILDKQKVVKLKQVEHTLNEKRILQAISFPFLVGLQYS FKDNSNLYMVLEFVTGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKP ENLLIDSQGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVY EMAAGYPPFFXDQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVN DIKMHKWFAATDWIAIYQKKVDAPFHPKCKGPGDPSNFDDYEEEPLRISSTEKCAKEFAE FXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXX----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---EEAFVTLARDIKAKMDKKLNDGETSADRNVEIWKIKKLIKSLEAARGNGTSMISLII PPKDQITRITKMLADEFGTASNIKSRVNRLSVLGAITSVQQRLKLYTKVPPNGLVSYCGT IVTDEGKEKKVNIDFEPFRPINTSLYLCDNKFHTEALTALLADDSKFGFIIMDGSCALFG TLSGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYMRKVAEVAVQLFITNDKP NVSSLVLAGSADFKTELSQSDMFDQRLQAKIIKIVDVSYGGENGFNQAIELAAEALGNVK FIQEKKLIGRYFDEVAQDSGKYCFGVVDTLKALEMGAIEILIVWENLDIIRYVLKNSATN EEKILHLKPEQEKDKTYFTDAETGVELELVESQSLLEWFANHYKDFGATLEIITDKSQEG AQFVKGFGGIGGILRYQVDFQSMEPLDDPELEFDLDDYITRSSQPLVGKRSKDDERYLQL IMDANAQSHKFYIVDARPQVNAVANKAKGGGYESEDAYQNAELIFVDIHNIHVMRESLRK LKEICYHPLDDAHWLSNIESTHWLDHIKQILAGAVRIADKVESNKTSVLVHCSDGWDRTA QLTSLAMLMLDPYYRTIKGFEVLVEKEWISFGHKFAQRVGHGDDKHSDSDRSPVFLQFID CVWQMTMQFPNAFEFNELFLITILDHLYSCLFGTFLGNSELQRKNEKVSEKTVSLWSYIN SQLDDFTNPLYKHVLLVVASMRKLRIWNNYYLRWNPQMKSQEPVNLRNRELLLLKQQLQK KLEELQKEYQIKM----------------------------------------------- ------------------------------------------------------------ ---PTFESVQALSNQVYHDLVSGNPKEVFTLLLNDHGFEIKSVDASVKILVSTIPPNFKK LDPQIHLDVKIMQEHLSAIRQTRWFEENASHSSIKVLVRLLHDLRARFSGLEPLSTWIIE LFAHHCVMNTPQRQPLSINVAFRRGLQLLAGGFFLPGSAGIYDPCEPNSIRAHTSLTLEQ QDQVCHTAQTLLRVLSHGGYSYILGFKNDLNITSQVTFWNGVVVTPSEKAYEREEEVIRL IEQYLKEQNLFRTLSVLQEETGINLNTVDSVDSFVTDINNGHWDTVLVAIQSLKLPDEKL IDLYEQIVLELIELRELGGARSLLRQTDPMTMMKQRYPDRYLHLENMLGRSYFDPREAYY EGQTKEKRRAAIAQALSGEVNVVPPSRLLSLLKQSLKWQQHQGLLPPGTTIDLFRGXAAM KEQEEEKYPTQLSKSIKFGQKSYIECAQFSPDGQ-------------------------- ------------------------------------------------------------ -------------FDHIIRIFGLKSGKALKEFRGHMSFVNDAIFSGDSHSIISSSSDGTL KIWSVKFGECTNTFKSLGSSSGLDVAVCSAHLLPSNPEQFVVCNRSSTVVVMNMQGQIVK SFSSGKREGGDFVCCTLFPRGEWLYCVGEDHVLYCFSFQTGKLERTLTVHEKEVAGITHH PHQNLISTYSVEGFMKLWKPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-- ------------------------------------------------------------ ------------------------------------------------------------ ---------------DLENYILELIPTLPELDKMDKSFYPFYVCTAVRKFSFFLDPLHTG KIKIQDILICGFLDHLLELRDEDMSKESQDANWFSAVSSIKVYGQYLHLDADRNGMLSKE ELAKYGSGKLTPAFLDRVFQECLTYEGEMDYKTFLDFVLALTHKDQPQSIQYLFQILDTQ HKGYLNVFDLHFFFKSILEQLRKNNQETVSFEDVKDEIFDMIKPVDPLKITCQDLIRCGQ AETIIGLLIDTSSFWSYENREIEYVRDHPFEVGPRYSNLAYIGEGAYGMVVSAIDHVTKT KVAIKKISPFEHQTYCQRTLREIKILTRFKHENIINIQDIIRAPTVDEMKDVYIVQCLME TDLYKLLKTQKLSNDHVCYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFG LARVADPNHDHTGFLTEYVATRWYRAPEIMLNSKGYSKAIDVWSVGCILAELLSNKPIYP GKHYLDQLNHILGVLGSPFSEDLNSIINDKARGYLQSLPFKPKXPWDKLA---------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------DLRFVGLMAMIDPPRAAVPDAVSKCRSAGIKVIMVT GDHPITAKAIAKGVGIISEGNETVEDIAARKGVAVAQVNPRDAKACVIHGTDLRDMTPAQ IDDVLRHHIEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIA GSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLLFILAD IPLPLGTITILCIDLGTDMVPAISLAYEQAESDIMKRKPRDPVNDKLVNSRLISMAYGQI GMIQALAGFFIYFVIMGENGFRPSRLFGLRKSWDSKNVNDLADSYGQEWSYAQRKALEFT CQTGFFVAIVIVQWADLVICKTRRNSVFHQGMLNIHLIFGLFFETTLAIFLCYCPGLDKG LRMYPLNWTWWVAPLPFSALILIYDEVRKHIIRRCPGGWVEKETYYSFKSLSKGKKAAFG IVGGTVGLATALQDNELHPPSYPWSHKGLLESFDHASIRRGYQVYKQVCAACHSMNYMYY RNLVGHVYNEKEAAREASEVDVLDGPDDQGNMFTRPGKLPDRFPNPYPNDEAAKAANGGV LPPDLTLIVNARHGGEDYVFSLLTGYCDPPAGVPVNPDLHYNAYFPGGWTGMARSLYNDV VQYDDGTPATSSQMAKDVVTFLKWCAEPEHDDRKRMGMKAMIIFILLIAFYYKRHKWSIL KSRKIAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMP QIMRLITKDLSEPYSIYTYRYFIHNWPKLCFLAMHKGECVGAIVCKLDFHKKHCKRGYIA MLAVAQGYRRKGIGSYLVIRAIKGMVSDNCDEVVLETEITNQAALHLYENLGFVRDKRLF RYYLNGVDALRLKLWLKTYLALQFHLPAGQQKCLKEEIHKDVLVTGEYLITEVPDQKASL KVKDSKGHFLYNKEDATKGKFAFTTDEFDMFEICFEDHVPQGTHGLDREVSLVLKTGVEA KNYADIAKAEKLKPMEVELKKLEDLSESIVNDFSYMRAREEEMRDTNESTHARVLYLSVF SMLCLLGLATWQVLYLKNYFKSKKLIEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXGDVFLEKHWKSVIHRSICDYFFESQSKAAAPDDVPPVLATPHQ YLINIYRNQIYFIAVVLKEVPPLFVIEFLHRVVSTFEDYFAECSESAIKDNYVVVYELLD EMLDNGFPLATESNVLKELIRPPNLLRTITDTVTGKSTNMSDTLPTGQLSNVPWRRTGVK YTNNEAYFDVVEEIDVIIDKSGSTVFAEIQGYIDCLIKLSGMPDPTLSF----------- ---------------------------------------------------------DIT IGPKQTMGKPVENVILEIPFPKSVLNATLTVTQGKYTFDPVSKVLTWDVGKIDPNKLPNI KGNIILQAGSPLPESNPTISVQFSISQLAVSGIKVNRLDMYGEKYKPFKGVKYVTKAGKF QVRTMATFLKSAPHYNTSDWFANNEGISVAAERERSVAQEVKQEARFLRNETNNRTKWDQ LDNNNRLADRIDDVRGWKDALERTLTKVEKEIKSLSESKEDLENLLESLNLPTEVNTENL ALREGRRGIDLVNDEVEAELNKEKMLIEQMKKNLQKMIEGSLEYMCRLQEVRQLIMADLQ DKNAAIDIDVEQYNLTDSS-MISFXPDPTRI----------------------------- -------------------------FCLRKRIHEVEQALDELNWQKQQTEEDMKELEDDI RKQEAAIRAKTNPMKLAQTRLENRSYRPNKELCLDGPHYGLTDEVHQLEATKRALQEKLY QSQHALSLLEKRLHGINREIQLKSQAVKLDKQCLESRYKLERNLDLTGL----------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------EDSMDLIAKLPTIAAIIYRNLY REGTSVGAIDPSKDWSANFTSQLGYEDPQFADLLRLYLTIHSDHEGGNVSAHTCHLVGSA LSDPYLSFAAGLNGLAGPLHGLANQEVLVFLKECSYTQDDLKNFVWAHLKSGQVVPGYGH AVLRVTDPRYTCQREFAQKYLPNDPLFKLVSDLYKIVPDILLSLGKVKNPWPNVDAHSGV LLQHYGMTEMNYYTVLFGVSRALGCLASLIWWRGFRFPLEGPKFYSTELLQKMVKMPFVA PQTEKCATCGKSVYAAERQEAGGNAYHKLCFKCSVCKLNLKLNNYAQADGLLYCKTDYQK AILAKNAQIDVLFVHRDTPENNQNTPFELTPENKKRAEAILRNYPKGFEASGIIPILDLC QRQHGWLPISAMNYVADYLKVSRMRIYEVATFYTMFKRSPVGKYHIQVCTTTPCMLGGCG CNPILETIKNKLGIGVGDTTKDKMFTLGEVECLGACANAPVAMVNDDYFEDLTPKDVEEI INDLVAGKKPKPGPRSGQNNRFAAEPAGGMTSLKEPPYGPGFKVRSDL-QKYEKLEKIGE GTYGTVFKAKNRETQEIVALKRVRLDDDDEGVPSSALREICLLKELNHKNIVRLCDVLHS EKKLTLVFEYSDQDLKKYFDSCNGEIDPDTVKSFMFQLLRGLAFCHSRNVLHRDLKPQNL LINKNGELKLADFGLTRAFGIPVRCYSAEVVTLWYRPPDVLFGAKSYSTSIDMWSAGCIF SEVANAGRPL-------------------------------------------------- ---------------------------------------TASKFMSYTGPVEGVHYPLND ICDGWPLEYCEFHPHYEKAKEWAEKNLADDVKDLIIKRQTRGGKGLIKMKQKQDEKKICL SRASRGKKKFVTVVSGLSTYEIDLKVASKFFGGRFSCGSSVTGEDEIVIQGDVKDDLFDV LVEKWPQIDEDTIEDLGDQKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXMVRFAQYLSKEKEAELERIAKAIVAPGKGILAADEST ATIGKRFASIGLENTEDNRRKYRQLLFSSLAESVSGVILYHETFYQKSDDGKTFPQVLKE NGIIPGIKVDTGVVNLAGTDNEVTTQGLDGLAERCAQYKKDGADFAKWRCVLKISSHTPS YQAMLENANVLARYASICQQNGIVPIVEPEVLPDGDHDLETAQKITEQVLAFVYKALADH NIFLEGTLLKPNMVTAGQSCPKKFTPEQVALATVQALRRTVPVAVPGVTFLSGGQSEEDA TIHLNAINNRPWALTFSYGRALQASVISAWKGKAELVQAAQQELLKRAKANGLAAVGKYH GGEGGAASQSLFVKDHAYYVASLPKVIKRRLKALKKLQVEVNHLEAAFFEELHKLECQYQ AKYQSLYDKRAEIVNAKVEPTDEECEWPEDSEDP--GLSVEEDESIKGVPEFWTMIFKNT DVIRSMVQPHDWPIMKHLQDIQLFLN-SFRLDFVFEDNEFFTNKVLSKTYYMRIQPDEEN PILYEGPEVYKCEGSPIQWKPGKDVTVRLVKKVQKHKCRGTKRVLTKTVPNDSFFNFFNP PLVKEDEMDEDTEVILESDFEIGQFFRERIIPRAVLYYTGESVEDEEEEDDEELD----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------KLPIGDVATQYFADRDMFCA GRVTEEDLKRTMQACGGSIQSTVSSLTLGVCELFEERQIGGERYNLLTGCTKAKTCTLIL RGGADQFIEETERSLHDAIMIVRRTIKNDAVVAGGGAIEMELSKYLRDYSRTVPGKEQLL INCMAKALEVIPRQLCDNAGFDATNVLNKLRQKHAGKWFGVDIISEGITDNFEACVWEPS LVKVNALTAASEAACLILSVDETVKNPRSTVDAAGLGRGRGRPMKGNNVIPNGHFHKDWK KNVKTWFNQPARKIRRRQHRAEKARAIAPRPTAGAHRPVVRCPTFKYNTKVRAGRGFTLL ELKNAGVNKRFARTVGIAVDYRRRNKSTESLQINSQRLKEYMAKLIVFPKNAAKPNAFEA TEEQVKMATQFTGEVIPIKVPVYKEKARAISEEEVKYSAFVALRQARAHARLAGKRAKKQ KEAMPNIKIFCGTSHVELAQKICDRLGIELGKVTTKKFSNQETCVEIGESVRGEDVFIVQ SGCGEVNDMIMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSPISAKLIANMLSTA GADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENIPEWKNSIIVSPDAGGAKRVT SIADKLNVDFALIHKERKKANEVASMVLVGDAKNKVAILVDDMADTCGTICHAAEKLFEA GALKVYSICTHGILSGRALDHINSSRFECVVVTNTIPQERNTELCNKLQVIDISMILAEA IRRTHNGESISYLFGHVPLLTCRFYEHRYPEIEDVVKVTVLSIAEMGAYVHLLEYNKIEG MILLSELSRRRIRSINKLIRIGREECVVVIRVDKEKGYIDLSKRRVSAEEVAKCEDKFAK AKCVNSILTHVAQLRGFETDAQLEDLYQKTAWHFDRKFGKPGAAYEAFKNAVVNPDVLNE CDIDEXTKKILLTDIKRKLTPQAAKIRAEIXVSCYGYXSIFAHQDALRAG---------- ----------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--QRKFFVGGNWKMN GTYKSIDEILTYLNGKDPNAEVVVAPPAVYLSYVKQKIIGVAAQNAYKEEKGAFTGDISP AMIKDIGAQWVILGHSERRHVFGESNQLIGEKVGHALAAGLKLIVCIGEKLEEREANKTE EVCFAQLKANDWKRVVVAYEPVWAIGTGKVATPDQAQEAHKSCRHWLSVNVSPDVAKNVR ILYGGSVTAGNCKELAKKIDVDGFLVGGASLKPEFIEIVNARXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------- ------------------------------------------------------------ -----------------------------------------------------KLKADPA KVEAFQSSLSKLGDVYINDAFGTAHRAHSSMVGCKLPNRASGFLLKKELTYFSKALEKPV KPFLAILGGAKVADKIQLIENLLDKVDEMIIGGGMAFTFLKVINNMKIGKSLFDEEGSKI VQKLMDKAKSKNVHVHLPVDFITGDKFAEDAVVGKATVEGGIPDNCLGLDIGPKSIEDFS KTVLKAKTIVWNGPPGVFEFKNFAVGSKAILDAVVKATQGGAISIIGGGDTATVCANYQA EDKVSHVSTGGGASLELLEGKVLPGVAALSDA---IPPKSWQPPFVTLETSMGTIEIELY WKHAPKTCANFAELARRGYYNNTKFHRIIKDFMIQGGDPTGTGKGGASIYGKSFEDEIAE DLRHTGAGIISMANSGLNTNGSQFFITLAPTQWLDGKHTIFGRVSKGIKILNRLGLVETD NSDRPTDDVKIL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------QVKELLTSFGPLKAFNLVKDVGTGLSKGYAFCEYLDQACLGLNGMMLG DKKLIVQRASVGKNPLAAMLTNLQIPGLNLSEVPTEILCLMNMVTPEELEDEEEYEEILD DVREECGKYGAVKSLEIPRPIKGVEVPGVGKIFIEFFTMDDCENAQQNLSGRKFANRVVV TSFIDPDKYHRREFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHRHSSP QRRREVVRPEERFGDRSELNPEQRDLRTIFCMQLSTRLQKGDLLDFFTKVGKVRDVHLIR DSKSHRSKGIAYIEFYEIESASRALEMSGSKLDGIPIIVQPSHGERNRSNGYMGPMKLYV GSLHYNITEDMLRGIFEPFGPIDELKIMRDHQTGRSAGFGFLQFRHGEDGKRALEQLNGF ELAGRPIKLGSVADYQI-SSLFDIDESDKVGFGMSATGRIQLMAKLAEGTGFQIPAAAAN VLQSVPTASSPPISTQCFILSNMFSHDEMDDNWERELKDEVIEECAKHGGVLHVHVDRHS RDGNIYVKCATIASAMTSVASLHGRFFAGKQITASYVPLPNYHNLFPDAVKATQPLSPST -AEEREGSPTPLTATKKRSRRGAVSAEVYTEEDAASYVKKVVPKDYKTMAALSKAIAKNV LFSHLDDNE--------------------------------------------YVSTIGE GGSFGELALIYGTPRAATVKAKSDVNLWGIDRDSYRRILMGSTIRKRKMY---------- ------------------------------------------------------------ ------------------------------------------------------------ -----SNYAGLARIYRLIHIAXY--------------------------------DAQWV DNTSKKAALKLERLDMDLKNYKTNSIKESIRRGHDDLGDHYLECGDLSNSLKCYSRARDY CTNSKNIVNMCLNVIKVSIYLQNWPHVLSYVSKAETSPYISEGKEPSNQIVTKLKVTAGL ADLVCGKYKAAAKQFLQANFDHVDFPELLSANNIACYGALCALATFDRQELQKLVISSSS FKLFLELELQLRDIVHQFHESKYASCLKLLEEIKDYLLLDMYLAQHVDNLYALIRNRALC QYFSPYKSADMKKMAESFNTTVSGLEDELMKLILEGKISARIDSHNKVLYAKDTDQRSIT FEKSLIIGEEFQRKTKALILRAAVTRNQLQVKSPPRENNQPLDLSMVAGNAVAXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXRKTVTMIPGDGVGPELMTSVKDVFSAARVPIDFEEIY VS---------------------------------------------------------- -----------------------NSAKIARFAFDYAIQHDRKKVTAVHKANIMKLGDGLF LDTCTQMAKRYPTIQFENLIVDNTCMQLVARPEQFDIMVMPNLYGNIIDNLAAGLVGGAG VVPGESHSTDVAVFEPGARHAFAESTGXDRANPTAILLCSANMLDHVGLEKYA------- -------------------------------SEDFQTFFSRASNLVERAIGEYVDIFTDY SGQEDDEGLSEGEQLKLNRNFFSERWSKNRTITSLDWSTQFPELLLASHNNNESQPQEPD GVVLVWNIKYKKTTPEFVFHYQSPVTSACFAKFHPNLIIGGTYSGHIVLWDNRSNKRTPI QRTPISASVHTHPVYCIEVVGTQNAHNLASISTDGKVCFWNLDMLS-------------- -------------NNFVLGTEEGVVYSACRHGNKAGILDLYEGHQGPVTGIDCHSVPGAV DFSSYFISSSFDWTVKLWNIRESAPLHSFEDNSEYIYDAKWSTVHPAIFSTVDGSGRLDL WNLNMDTEVPTASTIGVAANKCRWHQGGLNIGVGDDEGNVHIYDVAESLAIPRTDDWSKF SHTLQDLKLEQAEQNDDQIEKQLLAATGILEQQVDVALQELD-----DIADYRKKRLETL KRAKAQKEEWLKQGHGTFEEAADEKDFFNICKKXKNVVCHFYRSSTIYCEVVDKHLTLLA PRHLEAKFIKINAEKSPFLTEKLRIKVMPTICLIKDGKSVDFIVGFGDLGGKEDFQTRVL EQRIAKAGVIEYSDD--HAPAE--------------XXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-- ---------------------------------------------------QLKNKYGDA FIRGNNVLYISTQRRR-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXTVRPATPALEQTLFDYGKYVADCLPKFVQKVQVVHGCELEVMISPEGIIPVMTFLKD HTNAEFTNIVDICGVDVPTRQYRFEIVYNLLSIRFNQRIRVRTYTDELTPVESLTPLFAG ADWYEREVWDLYGVYFQNHPDLRRILTDYGFEGHPFRKDFPLVGYVEVRYDDELKRVVAE PVELVQEWRNFDYSSPWESFPKFRESLNPLCQVDYQAKLWNCNFCFHKNAFPPQYAAITE QHQPAELVPQFSTLEYTLTRAQCHPPVFLFVLDICIEEDELQALKESVQMSLSLMPPNAL VGLITFGRMVQIHELGCEGYLKSYAFKGTKDFSAKQLQEMLGIGKGAPQLPYSRFLQPVH KCEIALTDLLGELQRDPWPVAQGKRPLRSTGIAASIAVGLLECTYPNTGARIMLFMGGVC TQGPGMIVEDSLSCYIRTHRNIAADDCRYMKKAMKHYEALAHRAANNGHVFDIYACALDQ TGFLEMKYLPTFTGGHLVMCDSFNTSLFKQTFGKVFDKDSHNEFRMAFGATVEVKTSKEL KVQGCIGSCVSMNNTGSNISVDLGIGETCQWKMCGLYPNTTYAFFFEVASQHNNAVPQGS RAYIQFITHYQHSCGHIRIMVTTLTRNWVD-SMNIQSITAGF------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------QSIATWRKEGYQDRPGLENFKQLLRAPQDVPKDFLRVRFPMPRYIVTDAGGLQA RFLLTRVNPSRTHNNAEL-DGGMGFTDDVSLQVFXQHLKKLAVSN--XXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXSSNPAAVHKVIMVGSGGVGKSALTLQFKYDEFVEDYEPTKADSYR KKVVVDGVEVQVDILDDYAAIRDNYFRSGEGFLCVFSITEHESFLQTADFREQILRVKND DYIPFLLVGNKMDLDNKRQVTSQEAQTKAQQWKVSYVETSAKTKENVDKVFYDLMKLIRD KKNSKPSRKKKCTIL--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------RKGAKGTSEQEIETVLDKSX VLFRFLQEKDVFERYYKQHLAKRLLLNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFKD MTVSNSIMDEFRQHINNEKNLYGVDLFVRVLTTGFWPFQSSTTACNIPSAPRQAFETFRR FYLGKHSGRQLSLQPQHGSADLNAMFYGVKKTLASGKGGSRKHIIQVSTYQMVILMLFNN RESYSYEEIKNETDIPDRDLMRAMQSLALGKITQRVLTKDPKTKDIEPDHSFTVNDQFTS KLFRVKIQAVANKGDSEPERVETRSKVDEDRKHEIEAAIVRIMKARKRLQHNVLVAEVTE QLKARFLPSPVVIKKRIEGLIEREYLSRTPEDRKVYTYVADKISVFPSRMAMTNMKTRLK GAQKGHSLLKKKSDALTMRFRQILKKIIETKMLMGEVMKEAAFSLAEAKFAMGDFNHLVM QNVSKAKVTVSSKKDNVAGVLLPTFECDQDGPDSNVLLGLGRGGQQTERLKKNYSKAIEL LVDLASLQTSFIVLDEAIKVTNRRVNAIEHVIIPRIERTLDYITTELDEREREEFYRMKK IQRKKVQVRHAPNILHEDEDLLFPLKVVITGAAGQIAYSLFYPVARGDVFGSNQPISLVL LDIEAMLGALKGVVMELVDCAFPLLKEIIPTADANEAFQDADVAILVGAMPRKEGMERKD LLKANVRIFKTQGEAIDKHAKKNVKVVVVGNPANTNAFICKKYAPSIAPENFTCLTRLDQ NRAQSQIAYRQEVENVIIWGNHSSTQFPDVAHGFAVEEAVKDEAWLKGAFISIVQKRGAE VIAARKLSSALSAAKAICDHLHDWWFGTKEGHWVSMGVPSDGYGVEKGLIFSFPVSIGGS YTVIQGLNINGFAKEKLEATQNELIEERDQALEACXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXX-------------------------------------------------- -----------------------------------------------------QYRDMYY EGGVSSVYLWDLDHGFAGVILIKKAGDGSNKIKXAADSIHVVEVQEKSSGRAAHYKLTST AMLWLQTSKAGSGTMNLGGSLTRQAENDFNVNETNPHIANIGRMVEEMENKIRNTLNDIY FGKTKDIVHGLRTTQSAKKMMLQNDLASALNKRAQXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXRTPTLKERLMAPAGANAYGMGKAVTAGASAFALG SLCYYGLGLSNERGTIDTHIYWSETIRQRVRSTYSYLGGSILITAASRFPPLINFMMRAP TLAMFGSFVASVSSLLICKSMPYTEGAKQVAWMAFASTMGAGICPLVFLGGPLLARAAAY TAGIVGGLSTLAVCAPSEKFLYMGGPLAMGLGAIIVASIGSMFVPVTTAIGSSLYSISLY GGLVLFGGFVLYDTQHIIHRAERHPYNADVPFDPINACIGIYLDTVNIFIRIASILASGN SKRK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------YIRLWDVNSEMKRDIPLKFNSYTTSLSLNSYNSDMIVGGFID GTVRLFDKRLPKNECEL----RCLREHSARINKVVCPEGYELISASNHGEVFFWDSR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------XXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPVENFE EEGLAKIPNLELAQWKFLLQTEKYKNDHKIRCDLLKAVVDGNMAPFYEEICVDLQWNVDS SLLTNMKAENEKKIKEFDDSLEDAEKNQGEVEVRDIMLKKAEYYSSIGAKELALAQFRKV GEKTLTLGYKLDMEFHQIRIGLFYMDHELIKRSLEKAQSLIDQGGDWDRRNRLKVYRGTY CMAIRDFKMAASLFLDTVATFTSYELMDYKTFVTYTVFCSMIALPRPQQRDKVVRGSEIL EVLHSLPDIHRYLFSLYNCQYQEFFKHLAKVEQILKHDRYLAPHYSFYTREMRILAYTQL LESYRSLTLNYMAKAFGVTTEFIDQELSRFIAAGRLNCKIDKVGGIVETNRPDSKNYQYQ ETIKKGDILLNRIQKLSRVINI-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YGLCVAKAQYPIAELVQFLRSKGKSVK FGIHPVAGRMPGQLNVLLAEAGVPYDIVHEMDEVNPEINDIDLTLVIGANDTVNSAAEED PNSIIAGMPVIRVWLSKQVVVMKRTLGVGYAAVDNPIFFKNNTWMLLGDAKKTCDALLAK AKMERPPAIPGIPQGLEYLSQIDQLLIHQQVELFEMITGWETSNKYQIKNSLGQQVYFAG EESDACGRLCCGAQRGFVMHITDNFGAEVLRATRHFKCCAGCNCCANCAMELYIEAPVGQ ICGYARQTCITPHFVILDAVFNVVGPMCICQGPCCTRDQEFKIFTSLIGKLSKQWSGFAR EFFTDADNFSATFPLDLDVQMKAVLLCTVFLIDFMYFEQQQNXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMS RSEGLIQRKNAAADIEDHDSKEARLTLMEEVLLLGLKDKEGYTSFWNDCLSSGLRACIMA ELALRGRIELEKTGMRRRSLLNRKVLCKCDTPTGDALLDEALKHIKETKPAETTHAWIEY LSGETWNPMKLRYQLRNVRERLAKNLVEKGVCTTEKQNFVLFDMTTHPLNDSAVKLKLVK KVQDSVLTRWTNDVHRMDRRVLMLLILSHVSDVLENAFAPLSDDDYEVAMKRVRLMLELD PEEESQKDGANELLWAVVASLSKG---TQVTEENCEVCVKFLSKFINTLEKIENEFRKFC EDAKHKDNRFCYYVGGLKESATGMLGEISKPVSWSMPADKICQKLKKMDAQICDLKYDKK IDLAKVDFNKLKVGDLKRILSEWGETCRGCSEKSDFVRMVKDLLPKYAPEAVPDLILQGF KLNWMNLRDADTGKILWQSADDLSLPDTEHEARVPKKILKCRAVSREMNFSSVEQLTKFR LEQRVLFKGRCIEEWFFDFGFVIPCSTNTWQSVIEAAPEGQMMPASILSGHVVIETKFFD DDLLVSMSKVRIFYVMPKVVSKSTVCTDVKDQEEYQEEKPLNVYYCICGQISLILDCPIE KLPLRKLEGARVIDSSKHAHKIMCVADNVVYLKRKEGIEKQFRFKCQKCNLWLYYRHKNQ VTYIVEGALIKHGETRPDMYSQLSEPKKVMVTKHTKNMGKFSSVTVSTIDEEEDEIEAKE IADSYAANARVIEKQLLRKGINKSKLLEQAELEAKKGRPKGTLIDHAFSGFRNAGAQQKA GYADMAFTFASPVSVNVKQVDVPTLNGDFGILPQHVPLLAVLKPGVVSVHENDGALKKFF VSSGSVTINDDSSVQILVEEGCSVDQLDAQAIRDGATKAAQDLSSEKSKAEAQIALDCYD ALQKAVDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVFVPTDVTSVEDVKNALVTKS KFGCLNVAVNCAGLGIAAVVYNHNKDRIHSLEDFMRILTVNTGGTFNVICQASQMMARNK PTEDGEKGVIINTASIAAFDGQRGQAAYAASKAAIAGMTLPITRDLAISGIRVVTIAPGL FNTPLLADLPDKVKNFLSTTVPFPSRLGEVDEFAHLAQSIIENPMLNGETIRLDGGLR-- ------------------------------------------------------------ -----------------------------------------QDAIQYMCEEAPNAVIELE NFGMPFSRLDNGKIYQRAFGGQSLDFGNGGQAHRACCVADRTGHSMLHTLYGRSLKYDAD YFIEYFALDLIMENGQCKGVLALSLEDGNIHRFRANNTVLATGGYGRSYFSCTGAHTCTG DGTAMANRAGISSQDMEFVQFHPTGIYGAGCLITEGCRGEGGFLVNNKGERFME------ ------------------------------------------------XSETAMIFAGVD VTREPIPVIPTVHYNMGGVPTNYKGQVVQTNGQDYVVPGLFAAGEAASTSVHGANRLGAN SLLDLVVF-RACANTIEQLNKPGDPVPKISPNAGEATVANLDAIRHAKGSISTADLRLKM QKVMQEYAAVFRDGPTLKTGCDKLSLIWKEMNIKTTDRGMIWNSDLVETLELQNLMINSV LTAFSAENRRKSRGAHAREDFPNRDDELD------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------LGFNEE DEDNQTSSQPSIAGGGYEVPARLRTLHNLVIQYASQGRYEVAVPLCKQALDDLERTSGPD HPDVATMLNILALVYRDQGKYKDAANMLNDALQIREKSLGTDHPAVAATLNNLAVLYGKR GKYREAEPLCKRALVIREKVLGKDHPDVAKQLNNLALLCQNQGKYDEVEQYYQRALDIYQ SKMGPDDSNVDXTKNNLASA---------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-- --HSFGVEPISCHSWNKDRSQVAILNNNEVQIHSTRWTLKETLSDHTQRVTGIDWAPSSN QIVTCAADRNAYVWPALVVLGITRAATCVKWSPQGNKFAVGSGNRCVSVCYFDSANDWWT NKKIKKPIRSTITCLDWHPNNQILACGSTDFKARIYSACMKEVKDQPAPSTWGDKLVFAN LLAEFSSESGWVHGIRFSGNGEKLVWVGHDSSICVVDSILKTEHLPFMDVTWVNDNSLVV GGYDCIPLTYTYSNGSITFKNKMDSKRGGAMAHFRTQDSRGTVLSSLHQNTITQLSPHSG TKDKCTKLTTSAADGLLVVWDVKKEQESYVGFANLPNQVYRKSVKRGFEFTLMLVGESGL GKSTLMNSMFLTDLYNAQYPGPSLRSQKTVKVEKMQVVLKEGGVQLKLTVVDTPGFGDSV DNTNCWKPIIDYIDEQYNLYLNAESRVIRQVTEDTRVHCCLYFISPNGHGLKPLDIEVMK QLHEKVNIIPLISKADSMTVEECKNFKKIIMDEIAQHSIKIYEFEDEDEQKVMKKMKERI PFAVVGSNTVIEVGGKKVRARSYPWGVVEVENLEHNDFLSLRNMLIRTHLHDLKDVTNNV HYENFRYDKLLTSVKSPLLQIEEEKKEHEEKLKRMEAEMHTVFEAKVQEKKNKLQESDTE LRRRQEQMMKSLEQQEAEFLEMKKAFIAERDTWEEQIKMSRRYDSRTTIFSPEGRLYQVE YAMEAIGHAGTCLGILASDGVVIAAEKRNTNKLLDDVAFSEKIYKLHDDMACSVAGITSD ANVLINQLRLLSQRHLLQYREPIPCEQLVSLLCDVKQAYTQFGGKRPFGVSVLYMGWDPH YGFQLYQSDPSGNYGGWRATCIGNNSSVAISMLKQEYKDGETDLKQALDLCIKVLVKTLD TNKLTSDKVEIATLTRVNDKTIIRILKCNELDQLIKKYEADEAKFDAEKKK--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ LKDQLVASRHSQTPAIEKRYNDVMSRWQRLLQDSDARKQRLLRLQEQYRQVEDLYLTFAK KASAFNSWFENAEEDLTDPVRCNSVEEIRTLREAQDQFKASLSTAESDFNQLAQLDKQIK SFNVGPNPYTWFTMEALEDTWKNLQKIIQERDAELLSEQHRQEDNDDLRKQFAVTANAFH QWLTDTRAAMTEGSGTLEQQLEATKKKSAEVRSQRSLLKRIEELSASLEERLILDNRYTE HSTVGLAQQWDQLDQLGMRMQHNLEQQIQACNQSGVTEDALREFSMMFKHFDKDKTGRLN HQEFKSCLRALGNDLPMVEEGQKDPEFEDILNHVDPNRDGFVSLQEYMAFMISRETENVQ SAQEVEAAFRALTTGDKPYITSNELFANLTKEQAEYCRNRMKLYKDSTGRQLPDAFDYIS FTKDLFINXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIDKDDLESPQ LMAEYVKDIYEYLRCLEGSDVTGKMRAILVDWLVSVHQKFQLLQETLFLAVSILDRYLQD HIPRQNLQLAGVTSLWIAAKYEEMYSPELADFVYITDNAYKAYEWRHMECIMLRALDFRL GGPLPIHFLRRFSKAGQVSGEVHMLAKYIIELALMEPDMVHYLPSKLSAAALLISMRIQE WSHILEHYSRYSESDLKEVLHKLAILITQKLTAIKNKYSSSKFFRISRSER--------- -SRNRNRGRRHNNPSPGPDSDLERVFIWDLDETIIIFHSLLTGTYAQRYGKDPPTSVSMG LRMEEM------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------LVPACSIANIVKTSLGPVGLDKMLVDDVGDVTITNDGATILKLLEVDH PAAKVLVELAQLQDEEVGDGTTSVVVIAAELLKNADELVKQKIHPTSIISGYRLACKEAC KYIQENLTMSVDELGKQCIINAAKTSMSSKVIGPDDEFFAAMAVDAANAVKISDGKGGFK YPIKSINILKAHGMRAAESQLINGYALNCTIAAQAMPKKIVNAKIAFLDFSLQKAKMKLG VQVLVDDPSKLEAIRQRESDITKERIHKILSTGVNVILTTGGIDDLCTKYFVDSGAMAVR RCKKVDLKRIAKATGGQMIVTLANLEGEESFDASCIGQAEEVVQEKICDDELILIKGPKA RTSASIILRGANDFLLDEMERSLHDSLCVIKRVLESKSVVPGGGAVEAAVSIYLENFATS LSSREQSAIAEFANSLLVIPRQLAVNAALESTDLVAKLRAYHNSSQTKPEHKELKWLGLD LVEGKVRNNREAGVLEPTVSKIKSLKFATEAAITILRIDDMIKLAPEQK-SKSYQDACHA GELDDESAHLLASKSVLNNLLVEEKDLTVQYDIYNVGSSAAYDVRLFDGTFPENEFEVKI GSLSVKWNRIGPGNNVSHVVVLKPLRSGYFNFSAAEVSYLPSESEPQIGYTSSLGQGYFM EYKFYDRKFSAHVLDWLAFVIMTLPSLAIPYMLWHSSKSKYELSKQKKNSNASQKEKASK FLKVLELTENLKIFVETVAHENVSLVISRQVLSDFCSSLPSFPDNIGKDIAHFTLEKLQP RVVSFEEQVGLIRQHSASIYEREQNWREAAKILVGIPLETAQKQYSNDYKLSTYLKIARL YLEDEDPVQAEMYINRASMLQAESTSEELQIMYKACYARVLDFKRKFIEAAQRYNELSFK TCIAEDEKMTALKNALICTILAGAGQQRSRMLANLFKDERCQKLPAFAILEKMYLDRIIR NSELKDFAEMLQEHQKAITPDGSTILERAVIEHSMLSASKLYNNISFDELGTLLEIPPRK AEKIASQMITEGRMNGHIDQIDSIVHFESQDALPSWDKQIQSLCVQVNDLVEKIKLVDPE WMSKVEESQMSMKLTESVVKTFLVAKIFQENTERINSIDYSATGETLISSSDDDTIIIYD CQNGTPKRTLNSKKYGVDLIRYTHAANTAIHSSTKVDDTIRYLSLHDNKYIRYFQGHTKK VVTLCMSPIDDTFLSGSLDKTIRLWDLRSPNCQGLMNLPGRPVAAFDPEGLIFAAGINSE SLKLYDLRSFDKGPFATFKMQQDKDCDWTGLKFSPDGKLILISTNGQVTRLIDAFQGTPI QTYTGQANNKGLPLEASFSPDSQFVFSGSTDGKIHCWNTNTGAKVVVLNGKHTGPVQCVQ FNPKFMMLASACSNMTFWLPQVD-KNIKVELKGDKMNVGLITLNRPKALNALCDELMKEL NTTLDEFETNDKVNCLVLTGNEKAFAAGADIKEMQDLNFEVVHKTQFLGHWSRITSFRKP IIAAVDGYALGGGCELAMMCDIIYASDKAQFGQPEIILGTIPGAGGTQRLTKALGKSRAM EIILSGNRLSAQEALQLGLVSKVCPSNDLLNEALKLAEKIASNSPLVVAMAKEAINLSYE VGLSEGLDFEKKIFHQTFATEDRKEGMSAFIEKRSPVF-- >Lineus_viridis XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------TNAVQRDIDQAAKYIGAGAATV GVAGSRAGIGSVFGNLVIGYARNPGLKQQLFSYCILGFALSEAMGLFCLMMAFLILFAFM SHYKEASKAPAPTIHRIRITLTSRNVKSLEKVCADLIRGAKEKHLKVKGPVRMPTKVLRI TTRKTPCGEGSKTWDRFQLRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADMDQVM AFVEPAKQFSKDSIRLVKRCTKPDRKEFQKIAVATAIGFAIMGFIGFFVKLIHIPINNII VMATPISKKRKFVADGVFKAELNEFLTRELAEDGYSGVEVRVTPTRTEIIILATKTQNVL GEKGRRIRELTSVVQKRFSFPESTVELYAEKVATRGLCAIAQCESLRYKLIGGLAVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPTNDYVDTAVRHVLLRQ GVLGIKVKIMLPWDPTGKLGPKRPLPDHVSIVEP-----------------MSKRGRGGS SGGKFRISLALPVGAVINCADNTGAKNLYIIAVHGIKGRLNRLPSACLGDMVVATVKKGK PELRKKVMPAVVVRQRKCIRRKDGVFIYFEDNAGVIVNVKGEMKGSAITGPVAKECADLW PRIASNASSIRKGKVQKIQLGPQVTEGENVFGVAHIFASFNDTFVHVTDLSGKETIVRIT GGMKVKADRDEASPYAAMLAAQDVAERCKVLGITALHIKLRATGGNKTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRLXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPKV PLVCSKTFATPRRPFEKERLDQELKLIGEYGLRNKREVWRIKLTLAKIRKAARELLTLDE KDPKRLFEGNALLRRLVRIGVLDEGKMKLDYVLGLRLEDFMERRLQTQVFKLGLAKSIHH ARVLIRQRHIRVRTQVVNIPSYIVRLDSQKHIDFSLKSPFGGGRPGRVRRKNAKKGSGGG GGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMPLARDLLNPRIEEEKQKCKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQSVVLCV GCSTVLCQPTGGKARLTEGCSFRRKQHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXVAEMPEIKLFGRWSSDDVQVGDISLTDYIAVKEKYSKYLPHSAGRYQVKRFR KAQCPIVERLCSSLMMHGRNNGKKLMAVRIVRHAFEIIHLLTGENPLQVLVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREASFRSIRTIAECLSDELINAAK GSSNSYAIKKKDELERVAKSNRMSEQMTLRGTLKGHTKDVTQIAANSRYPELLLSSSRDK SLIVWQLKKEGDYGTAKKKMTGHGHFISDVVISSDGMFALSGSWDKTLRLWDLATQKTTR HFNGHTNDVLSVAFSPDNRQIVSGSRDKTVKLWNTLGVCKYTIDEGHSDWVSCVRFSPNT AVPIIVSSGWDKIVKVWNLTNCKLKTNHYGHTGNLNCVTVSPDGSLCASGGKDKQAMLWD LNEXQHLYTLXGGDQINAL----------------------------------------- -----------------------------------MREYKLVVLGSGGVGKSAMTVQFVQ GIFVEKYDPTIEDSYRKQVEIDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKLARQFNCSFMETSAKSK INVNEIF--------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXMSDAEGDDQPT--VGAGAMDINTALQEVLKTALIHDGLARGLHEC TKALDTRRAVLCVLANNCDEPGYTKLVEALCAEHTINLIKIENKKKLGEWAGLCKIDKDG KPRKVVGCSCVVVKDYGKETQAYDVLTEYFKSK--------------------------- ------------------------------------------------------------ --------------PEVKHFCPNVPIILVGNKKDLRNDPNTMRELAKMKQEPVKGEDGRS MKDRISAYAYLECSAKTKEGVREVFETATKAALQMKKKKK--XXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----SAKILKPGGEKPDEFEQSISQ AILELEMNSDLKSSLRELYITAAKEIDVQGKKAIIIFVPVPQLKSFQKIQTRLVRELEKK FSGKHVVFIAQRRILPKPTRKTRTKNKQKRPMSRTLTAVHDAFLEDLCYPAECVGKRVRI KLDGTRLIKVHLDKTQQTNIEHKLETFTAVYKKLTGKDVVFEFPEYVLGRGGFRGGFGGR GRGRGRGRGRGKE-DKEWVPVTKLGRLVKDTKIKSLEDIYLFSLPIKEFEIIDLFLESKL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDHDGHVGLGVKCSKEVATAIRGAIILAKLSV VPVRRGYWGNKIGKPHTVPCKVTGKCGSVVVRLIPAPRGTGIVSAPVPKKLLQMAGIEDC YTCARGQTATLGNFAKATYSAIAATYSYLTPDLWKDLPFVKPPYQEFTDYLAKMSGGLDV LALKEEDVTKFLACSTHLGANTSDFQMDAYVYKCKSDGVHIINLRKTWEKLLMAARAIAA IENPADVCVISARPYGQRAVLKFASATGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDP RTDHQPVQEASYVNIPVIALCNTDSPLKYVDIAIPCNNKGPHSIGLMWWMLAREVLRLRG SISREVPWDVMVDLYFYRDPEEAEKE---------------------------------- -------MKFNKMVTSSRRKNRKRYFNAPSHVRRKLMSSPLSKELRQKYNVRSMPVRKDD EVQVVRGHFKGQQVGKIVQVYRKKFVIHIERIQRDKANGATVNVGIHPSKVVIVKLKLDK DRKRILDRKSKSRASGKHTEESIASPSSTNVGGTVRQRKTTTTAGGGAGMWRFYTEDSPG IKVGPVPVLVMSLLFIASVFMLHIWGKYTR-XXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---DKLARRIGGKGAMRRKKKVIHRTAMTD DRKLTGALKKLGVNTIPQIEEVNMIKDDGYVIHFNNPKVQASLAANTFSVIGQSETKQIT EMLPGIISQLGTEGLTHLQKLAESTDDID-EDDEVPELVENFDVASKGEMTRYSLDPENA TKSAKARGSHLRVHFKNTRETAMAVKKMPLGRAKRFLKNVCEKKEIVVFRRFNGGVGRHA QAKQFGATQGRWPKKSATFLLQLLKNAESNAEYKGLDTDHLMIEHIQVNRAPQMRRRTYR AHGRINPYMSSPCHIEVILAEKEQVVSKPVKKKVSQKKLKRQKMTMRDXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXMGISRDKWHKRRKTGGRREPIRKKRKFELGRPAAGTKLGA KRIHTVRTRGGNKKYRALRLDTGNFSWGSESQTRKTRVIDVVYNASNNELVRTKTLVKNC IVQIDAAPFRQWYEAHYALQLGRKKGAKLTEAEEAGINKRSKKTQKKYEERKKTAKVETA IEEQFATGRLYACVSSRPGQCGRCDGYILEGKELEFYHRKIKAKKGKXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXNSGTESDSDESVPELEDMSATTGVHEEPISKAKQSRSEKKA RKALLKHNLRPVTGVSRVTIRKAKNILFVIPKADVYKSPASDTYIIFGEAKIEDLSNQAQ ISAAEKFKSDDEIDETGLLSNDIELVMEQASVKRAKAVRALKNNENDIVNAIMMGRVRTK TIKKAGRVIIEKYYPRLTLDFHTNKRICEEIAIIPSKRLRNMIAGFVTHLMQRIQCGSVR GISIKLQEEERERRDNYVPDVSAIEEVDPDTKEMLKMLDFANIPGLQVTQPITQTXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMRELRIRKL CLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAE EILERGLKVREYELRKGNFSDTGNFGYGIQEHIDLGIKYDPSIGIYGMDFFVVLGRPGFN VAHKRRKRGKVGYKHKITKEESMKWFQQKYDGIILPXKMGIKFLEFVKPFCAVLPEISKP ERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGIS PIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMVITVGQAIVYVMTGMYGDPAD IGAGVCLLIIIQLFVAGLIVLLLDKLLQKGYGLGSGISLFIATNICETIVW--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------GALSVLADFLGAIG SGTGILLAVTIIYQYFEIFVKEQSEMGGMSTLLFQTEKAFQKQPTIFLNKKKALLPRYYK SVGLGFKTPREAIEGTYIDKKCPFTGNVNIRGRILSGTVLKMKMQRTIVIRRDYLHYVRK YNRFEKRHKNMSVHLSPCFRDVKLGDIVTVGECRPLSKTVKFNVVKVTKGSGSKKGFEKF MVNVPKQRRTFCKGKNCKKHTLHKVTQYKAGKATLFAQGKRRYDRKQSGYGGQTKPVFHK KAKTTKKIVLRMECTECKYRKQLPIKRCKHFELGGDKKRKGQMIQFMGRVIRAQRKGAGS VFKSHTKTRKGAAKLRAVDYAERHGYIKGVVKDIIHDPGRGAPLARVVFRDPYKYKLRTE TFLASEGLYTGQFIYCGKKASLQTGNILPVGSMPEGTIICCLEEKTGDRGRLARTSGNYA TVISHNPDTKRSRVKLPSGFKKVIPSANRAMVGIIAGGGRIEKPMLKAGRAYHKYKVKRN SWPKVRGVAMNPVEHPHG------------------------------------------ -AKRTKKVGIVGKYGTRYGASLRKTIKKMEVTQHSKYTCHFCGKDAMKRQAVGIWHCKGC KKTVAGGAWIYATTTAASARSAVRRFREMKDMGRRPARCYRYCKNKPYPKSRFCRGVPDP KIRIFDLGRKKAEVDDFPLCIHLVSDEYEQLSSEALEAGRICCNKYMVKTCGKEGFHIRI RVHPFHVLRINKMLSCAGADRLQTGMRGAFGKPQGTVARVNIGQPIMSVRARENHKANVI EALRRAKFKFPGRQKIILSRKWGFTKWEKPLYEEMRADGRLVPDGVSAQYRPHHGPLKKW MAAQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGAYKYMQELYRKKQSDVLR FLLRVRCWHYRQLSTIHRVSRPTRPDKARRLGYRAKQGFCVYRIRVRRGGRKRPVAKGAV YGKPVHQGVNQLKFNRSHQSVAEERVGRKCGSLRVMNSYWVAQDSTYKYFEIIMVDPFHK AIRRCPDLQWICTSKAKHREMRGLTSAGRKSRGLGKGHAYNSTIGGSKKAAWRRNN---- ----GICLGRLSEERKAWRKDHPFGFVARPVKNPDGTLNLMMWECAIPGKKGTPWEGGVY KLTMTFKDDYPSTPPKCKFVPPLFHPNVYPSGTVCLSLLDDDKDWRPAVTIKQILLGIQD LLNDPNVRDPAQAEAYTIFCQDRTEYDKRVRKQA--------GKSSKMLQHINYRMRCTL QDGRVFVGTFKAFDKHMNLILGDCDEFRRVRPKSSKQREEKRVLGLVLLRGENLVSMTVE GPPSSEEGMPRVPAAGAGPGPGMGRAVGRGMG-GGGLQGPVRGVGGPSSSMMAPG----- ----PKIPAVKLVLVGDGGVGKTTFVKRHQTGEFEKKYVATLGVEVHPLEFYSNRGKLLF NVWDTAGQKKFGGLRDGYYIQGQCAIIMFDVTSRVTYKSVPNWHRDLVRVCEGIPMVLCG NKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLGRKLVGDPNLEFVEMPA LTPPDVHMDPKLAQIYEQEIREAASTCL-------XXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX VRLPPEVNRILYIRNLPYRITAEEMYDIFGKYGAIRQMRMGVTPETKGTAFVVYEDIFDA KNACDHLSGFNVCNRYLVVLYYQSNKAFKKIDTEKKKQELDQMKAKYGLSTPE--XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXMPRGPKKHLKRLNAPKHWMLDKLSGVFAPKPSCGPHKMRECLPLTIFLRN RLKYALTYDECVKIVMQRLIKVDGKVRTDKNYPAGFMDVVSIEKTNENFRLIYDVKGRFA IHRITPEEAKYKLCKVKKLGVAAKGVPYVVTHDGRTIRYPDPL---------XXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXSGGGQGDKKDDKDKKRKYEPPVPTRVGKKKRKS KGPDAANKLPQVTPHTRCRLKLLKMERIKDFLLMEEEFIKNQERLKPQEEKNEEERSKVD DLRGTPMSVGNLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDALEPGCSVLLNHKVHAVV GVLGDDTDPMVTVMKLDKAPQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIK--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------XXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMAPTKKTKK AIENINSRLALVMKSGKCVLGYKQTLKTLRQGKAKLVIIANNTPPLRKSEIEYYAMLAKT GVHHYNGNNIDLGTACGKYFRVTVLSITDPGDSDIIRSMP--XXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKIELCA FSGYKVYPGHGKKLVKIDGKVYQFVSAKAEASFLMKRNPRKISWTVLYRRKHKKGQQEEQ SKKRTRRTTKFQRAITGATLMDIMAKRNQKPEVRKAQREQAIRAAKEKTKTKKSKAPKVG GKRMKLNISYPATGCQKLVEVNDDLKLRNFYEKRMSAEVNGECLGDEWKGYVFRISGGND KQGFPMKQGVLTTGRVRLLLSDGHSCFHARRSGERKRKSVRGCIVDAQLSVLCLVIVKKG EADIPGLTDTTIPRRLGPKRATKIRKLFNLSKEDDVRQYVVRRPLEQQTKAPKIQRLVTP VVLQRKRRRMALKKKHTAKKKEAAAEYAKLLA---------------------KVKAKEL RTRKKEELLKQLDDLKQELAALRVTKVTGGAASKLSKIHVVRKSIARVYTVIHQKQKENL RKYYKPKDLRKKKTRAMRRALTPHEKSLKSSKQIRKERAFPMRKYAVK---KGPKVTDKV FFDITIGGEDAGRIVIGLFGKTVPKTVANFKTIAEGTETYKGSGFHRVIKDFMIQGGDFT NHDGTGGRGVEFPDENFKLKHYGPGWMSMANAGPDTNGSQFFITTVKTPWLDGRHVVFGA VLEGMDVVRKIEN-----------------------------------XXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXX----------------AIKSTEDVVLVLRFGREHDPTCLQLDDILA KCEEELSRMAKIYTVEIDSVPVYCRYFDISLIPATIFFFNAQHMKVDWGTPDHTKFIGSF RTKQDFIDVIETLYRGAMRGKVMVPSPLD-------XXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------AIMKDFRSGASRVLITTDVWARGIDVQQVSLVINYDLPNN RELYIHRIGRSGRFGRKGVAINFVKSDDIRILRDIEQYYSTQIDEMPMNVADLIXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLV TMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTMPNSFKTLDSWRDEFLIQASPRDPEN FPFVVIGNKIDLENRAVSAKRAQGWCHSKGDIPYFETSA--------------------- --------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------GVNKMDSTEPPYSENRFNEIQKEVSGYLKKIGYNPKAVAFVPI SGWHGDNMLKMQWHKGWTVGSGKTLFDALDSILPPKRPTDKALRIPLQDVYKIGGIGTVP VGRVETGILKPGLVVNFAPPNITTEVKSVEMHHESLTEALPGDNVGFNVKNVSVKEIKRG MVAGDNKNDPPKGCENFTAQVIILNHPGEIHAGYSPVLDCHTAHIACKFLEFKEKIDRRS GKKLEDNPKMVKSGDAAIAVLQPSKPMVVESFVDYPPLGRFAVRDMKQTVAVGVIKSVIK KDPTSGKMTKAAVKAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPRQ INEIKDFLLTARRKDAKSVKIKKNVKFKVRCSRFLYTLVIQDREKAEKLKQSLPPGLAVK ELKMSKLSRETLNEAVSAILAKKRKFTESVELQISLKNYDPQKDKRFTGTVKLKNIPRPK LKICVLGDQQHCDEAKANELPNMDVEALKKLNKNKKLVKKLAKKYDGFLASDSLIKQIPR ILGPGLNKAGKFPSVLSHNEAMVAKIEESKATIKFQMKKVLCLSAAVGHVQMTQDELVAN CILAINFLVSLLKKNWQNVKALYVKSTMGPPQRIYXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXX-----IQNFKDPFALEGAIHIRLQQRNGRKTLTTVQGLVIPKYEKAV LKKWKRDFSCNGTLIE--DNGEIIQLQGDHCNDIMTFLINKEMKNQIKVH--XXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------KRARVGIKAPGIIPRTSVKEPMLS GIKAVDSLVPIGRGQRELIIGDRQTGKTAVALDTILNQRRFNDDSDEKKKLYCIYVAIGQ KRSTVAQIVQRLTNHDAMKYTIVVCATASDAAPLQYLAPYSGCAMGEYFRDNGKHALIIY DDLSKQAVAYRQMSLLLRRLPGREAYPGDVFYLHSRLLERAAKMNDSFGGGSLTA----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPIIIDARGHLLG RLASIVAKTILNGQRVVILRCEEINISGSFYRNKLKYLDFIKKRCNVNPKRGPFHFRAPS KIFWRTVRGMVPHKLSRGKEALDRLKVFEGIPQPYDKEKRMVVPAALKVLRLHPRRKSCR LGRISHEIGWKYQNVVNTLEGRRRAKSAEFYRRKKAETIWRTKATKIASQQKIIESYGYX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIFVERTLAIIKPDAVAE EIEDIILRSGFTILQKRRVHLTPEQASDFYAEHFGKLFFPSLVAYMSSGPIIAFVLSKEK AITYWRELIGPTNTLKARQTHPDCLRAIYGTDDQRNALHGSDSQSSGEREIRFFFPDSVV EPILTGQAARDYLSKSVNPTLXQGLTELCKTKPSEPV------------------MFEAK LENGSMWRKIVEAVKDIIENAIFDCSSNGIKLQGMDSSHICLVHLELHKEGFNSYRCDRN IALGVKVENLLKLLKCAGANDAITFRAENGGDTLMLIFESPAPNKISKYEMKLIDLDQEH LGIPDXDYSCTVKMP--------------------------------------------- ------------------------------------------------------------ ----------------KTVASYHTSRGVTPGQVVAVIGAVVDVQFEDELPPILSALEVEN RTPRLILEVAQHLGENTVRTIAMDGTEGLVRGQKCNDTGYPIRIPVGPETLGRIINVIGE PIDERGPVPTDRRASIHAEAPEFVEMSVQXEILATGIKVVDMLAPYAQGGKIGLFGGAGV GKTVLIMEL--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------MLMPKKNRIMIFEHLFKEGVIVAKKDNSLPKHPEVEVPNLHVI KALQSLKSQGYVKEQFAWRHFYWYLTNEGIQYLRDFLHLPPEIVPSTLKRQFGGADRQAY RRGGRGDKKGDVGAGATXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX MTNPKGYRRGTRYMFSRQFKKKGVTHLSKYLKCYRRGDIVDIKGDGAIQKGMPHKSYHGR TGRVYNVTQHAVGVIVNKRVRGKILAKRINLRIEHVKHSNCRLDFLNRVKRNEVIKREAR VKPECKRLPQGPKKAHFVRTKGNLPQVFEPIPYEFVATSRPSYKDIAEKEPSMDMRDITD RAATTAFWTELFRGFGITLSMIFKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAICPAQAITIEAESRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEY STETHEELLYNKEKLLTNGDRWEVEIAANLQADHLYRXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXKKLTREEELLLQDFSRNVTTKSSALFYGNAFIVSAIPIWLFWR IHQMDPSVLFGVMTLISTYLVAFAYKNVKFVLKHKIALKREEAVSREVMKKVADDKRMSK KEKDERILWKKNEVADYEATTFSIFYNNALYLVLMVVASFYLLRSINSTVNYILSVVLSS GLLALFSTSTK------------------------------------------------- ------------------------------------------------------------ ---------AGNKADLRSVTFEEARSYAEDNGFIFRETSAKTGQNVSDVFLQIARKMPKG VTSLNSDG--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAQKTWEMSNNIENV NIVEEIYRYDKKQQQDILTAKPWEKDPHYFKHIKISALALLKMVMHSRSGGNLEVMGLLL GKVDGNTMITMDSFALPVEGTETRVNAQAQAYEYMAAYTEAAKQVGRLENVIGWYHSHPX YGCWLSGIDV-------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPSYGDLG KSARDLFNKGYNYGFFKLECKTRANNGMEFTTSGNHNSDSGKVSGSLETKYKWVDYGLTF TEKWNTDNVLATEVTIEDQLALGQKLTFETSFAPHSGKKTGKIKVGCKRDFFNLNCDVDF DFAGPSVHAAGVLGYHGWLAGYQISFDKSKVTKNNFGVGYAGEDFTL------------- ------------------------------------------------------------ -----------------------------IDTVREKALTDYRKKLLEHKELEARLKEMRE QLKEFTKQYDKSENDLKALQSVGQIVGEVLKQLTEDKFIVKATNGPRYVVGCRRQIDKSK LRAGTRVALDMTTLTIMRYLPREVDPLVYNMSTEDPGDITYSQIGGLGEQIRELREVIEL PLMNPELFQRVGITPPKGCLLFGPPGTGKTLLARAVASQLEANFLKVVSSAIVDKYIGES ARLIREMFG--------------------------------------------------- ------------------------------------------------------------ --------------------------------------------------------XXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXMGKFMKSGKVVLVLNGRFAGRKAVIVKNYDEGTSEKPYGHALVA GVDRYPRKVTKRMGKKKIKQRSKIKAFVKVYNFNHLMPTRYSVVNLEKSLVNKDSFRDPA LKRKARREVKGKLEERYKTGKNKWFFQKLRFXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-- ---------KAKDKALRAKKNVLRGVQNKRSRKIRTSVHFRRPKTLKLARAPKYPRRSTP KRPRLDQFKIVKFPLTTESAMKKIEDNNTLVFVVDKRANKPQIKLAVKKLYDIDVAKVNT LIRPDGEKKAYVRLAPDYDALDVANKIGIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX---IFCKINRNEIPSEKLHEDDKCYVVRDICPQAPVHLLVIPK KCVESLAEDTLLLGHFLRIADKVAVKEDGYRTVINTGQDGGQDVMHLHIHVLGKREMEWP P----------------------------------------------------------- ----------QTSIRPYWRCYYSNTDAILYVVDSSDRDRISVSKNELVSMLEEDELKKAI LVVLANKQDLEGAMKKAEVSNALGLTAIKNRQWTIVPTSAVKGEGLKDAMEWLAEALKHP KXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXRLYNKAVFTGYKRGLRNQHENTALLKIEGVLTKKETAFYLGKKCCYVYKA KNKTACPGHDKSSHIRVIWGKVTRPHGNSGAVRAKFRRNLPAKAMGRRIRVMMYXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXMAARPLITVYSDKNETTGTNITLPAVFRAPIRPDIVNFVHFEMLKNTRQPYAV SVQAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRK INVNQRRYAMCSAIAATGIPALVMSKGHRIEETPEIPLVVSDKVEEIKKTKEAVSFLKKF KAWADIEKVYNSKRFRAGKGKMRNRRRIQRR----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--HRKFSAPRHGSLGFLPKKRSKRHRGKV KAFPKDDRTKPCHLTAFLGYKAGMTHLVREADRPGSKINKKEIVEAVTIVETPPMIVVGC VGYVETPKGLRTFKTIFAEHLGEECRRRFYKNWYRSKKKAFTKYSKKWQDEAGKKAIECD FRLIKKYCKVIRVIAHTQMKLMKKRQKKAHIMEIQVNGGTVSQKVNFVREHMEKKIXINT V----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQVPESLLKKRKQNAEAMRAKRSVIFKRAE KYVKEYRNKEKDEIRLSREAKKHGNFYVPEQPKLAFVTRIRGINGVHPKPRKVMQLFRLR QINNGVFVKLNKATLHMLRIAEPFISWGYPNLKSVRELVYKRGYGKIDNRRTALTDNAII EQKLSKFGIICMEDLIHEIFTVGPNFKQASHFLWPFK----------------------- ------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXMAPRYEMACGLHKGHKVTVRKPRPSRRKGALTKHTKFIRDVVR DVAGYAPYERRCIELLRVSRDKRALKFVKKRV---------------------------- ----------------------------------IMYVKNNKEADNDWFRLETNEKGTRW FGKCWYIHELLKYEFDVEFDIPVTYPTTAPEIALPELDGKTAKMYRGGKICLTDHFKPLW ARNVPKFGIAHAMALGLGPWLAVEIPDLISKGIVHHKEXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXKPPFKVANMDLAEMGRSSITIAENEMPGLMEMRRRHGAAKPL KGARIAGCLHMTVQTAVLIETLKELGADVQWSSCNIFSTQDFAAAAIAKTGVPVYAWKGE TDEEYAWCIEQTLIFPDGEPLNMILDDGGDLTNLVHEKYPQYLKGIKGLSEETTTGVHNL YKMMKAGKLKVPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGKVCVVAGYGDV GKGSAHALRAFGARVLITEIDPINALQAAMEGFEVTTMDEAVKEARIFVTATGCKGILGQ EHFTQMLEDSIVCNIGHFDCEINVAWL------KSEVKPQVERYTLPNGRHIILLAEGRL VNLGCAHGHPSFVMSNSFTNQVLAQIELWTKADQYELGVHFLPKNLDEEVARLHLDHLGV KLTKLTTEQSEYLGLPQAGPFKPDHYRYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------- ----GAKINENRVIKAA-EETSCEFGSAKYYALCGFGGILSCGITHTALVPLDLIKCRIQ VDPAKYKSIFRGFQVTVAEEGARALAKGWAPTFIGYSMQGLGKFGFYEVFKNVYSNMIGE EMTYSYRTSLYLAASASAEFFADIALCPMEAVKVRVQTMPGFANTLREGFPKILNNEGFN GFYXGLVPLWARQIPYTMMKFACFER---------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------YFNYNDVGFTGACKLLWT--XXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------DFTSLPRLIVI RSFDVNKPGFEVEDLRGGVAGGSILRGVLKVGQEIEVRPGIVSKDDEGKLSCKPIFSRIV SLYAEQNDLQYAVPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIYTELEISYFRLR RLLGVRTEGDKRGARVQKLSKGEILMVNIGSLSSGGRVIAVKSELAKIGLTNPVCTEI-- ----------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------------------- --------------------------------KYEHLRQFCMELNGLAVRLQQDCNPETC TQMTATEQWIFLCAAHKTPKECPAIDYTRHTLDGAACLLNSNKYFPSRVSIKESSVAKLG SVCRRVYRIFSHAYFHHKQIFDEYENETALCKRFTTFVMKYNLMSKDNLIVPILEEQXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVKKQGKGGKKGGKKKIVDPFTKKD WYDVKAPSMFNIRQIGKTLVTRTQGTKIASDGLKGRVFECSLADLQNDEVAFRKFKLMCE EVQGKNLLTNFHGMDLTTDKLKSMVKKWQTLIEAHVEVKTTDGYYLSLFCIGFTKKRQNQ VKKTCYAQTTQIRAIRKKMVDIMTREVASNDLKDVVNKLIPDSIGKDIEKTCQGIYPLHD VFIRKVKIVKNPKFDLGNL---------------------------------XXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XX---------------------------------------------------------- ------------------------------------------------------------ -----------------------------GKFELSWTPKGGAEQKMTVFEFKDGGGVGIG MYNTDESIKGFAHSCFQYAIMKKIPLYLSTKNTILKRYDGRFKDIFEEIF-PQYKADFDK AGIWYEHRLIDDMVAQALKSTGGFVWACKNYDGDVQSDVVAQGYGSLGLMTSVLVCPDGK TIESEAAHGTVTRHYREHQKGNPTSTNPIASIFAWT------------------------ ---------------------------------------------XXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFGDLKTDSGLKALNDFLLER SYIEGYQPSQADAVVFSALSGPKEELCNVLRWYNHIKSYGNETKSFAGAKRAVDQYGPSG AKPAADSDDDDIFGSEMEAMRKEKLAAEAAKK-NVVIGKSNIILAVKGYGDETDFNEVEK IVRAVEHQGLLWGASKLEEVAYGVKQMLITCVV--------------------------- -----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMAEFDLTKNISPYLDRHLVFPLLEFLSVK ELYDEKEMLKGKLDLLSNTNMVDFAMDVHKNLYPDQDVPKTLRDKRGDVVSDLKKLQADV EPITKIFEDPEVQIQTSRDGRQLYDFLAKNHGFQVEYLDTLYKFAKFQYECGNYSGAAEY LYFVRVLILPNDKNFLNVLWGKLASEILMQNWETALEDLTRLKDVIESALQSLQQRTWXI HW---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX-PKYYCDYCDTYLTHDSPSVRKTHCNGRKHKENVRLYYQKWLE EQVQKLVDDTTAQFKSG------------------------------------------- -----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXX---LMALAVADPTIHFQESFWKEHWLESTHR-SDQ GKWEWSAGKFYGDADLDKGIQTSQDARFYGISAKFEEPFTNEGKTLVIQFTVKHEQNIDC GGGYAKIFASSLDQKDMHGDTPYYIMFGPDICGPGTKKVHVIFNYKGKNLLTKKDIRCKD DEFTHLYTLILRSDNTYEVKIDNAKVESGELEADWEILPLQDIKDP-------------- ------------------------------------------------------------ ------------------------NIGAIGFDLWQVKSGTIFDNILITDDEAHAEMVGND TWGKTKDGEKKMKEAMDEADRKKQEEESKKEKDDDKEEDEAKDDXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTFLFTSESVGEGHPDKICDQV SDAVLDAHLRQDDHAKVACETTSKTGMILLCGEITSKANVDYQKVVRDTIKLIGYDDSKK GFDYKTCNVLVALEQQSPDIAQGVHEDRDEDDIGAGDQGLMFGYATDETEELMPLTVVLS HQLNAKIAELRRNGVLPWARPDSKSQVTAEYRFEDGACVPVRIHTVVISCQHDEDVTLEQ LRKDLKEKVVDVVIPAKYMDKRTVLHLNPAGRFVIGGPQGDAGLTGRKIIVDTYGGWGAH GGGAFSGKDFSKVDRSAAYAARWVAKSLVAANLCRRVLVQVSYAIGIAQPLSISVFSYGT SDMTEKQLLEVVKNNFDLRPGEIVKALDLRKPIYQNTASYGHFGRKEFSWEQPKKLRIXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMRLEKCYFCSSTVYPGH GVEFVRNDCKIFRFCRSKCHKAFKKKRNPRKTKWTKAFRKAVGKDLAVDPSFEFEKRRHE PVKYQRELWTKTVKAMKRVEEIKVKRQNQHIANRLKKGKELRKEADIKEVQKNIHLIKSP A--MAKYTIVLVRHGESAWNKENRFCGWHDADLSSIGIEEAKNGARMLKEKGYTFDVAYT SLLKRAIKTLNLVLDEMDLDWIPVHKHWRLNERMYGGLQGLNKSETAAKHGEDQVKIWRR SYDIPPPTLTVDDKRWPGHDRRYADMDQKLVPVTECLKDTVERVLPYWFDQIVPAIKRGE RVLISAHGNSLRGLVKYL------------------------------------------ -------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXMGIDICHKKDRKVHRTEPKSEDPYLRLLVKLYRFLARRTDA KFNKIILKRLFMSRTNRPPLSLARLIRHMKRDQNGKKIAVIVGTVTDDVRILEVPKMTVC ALHVTEGARARILKAGGTIITFDQLALKSPKGKNTLLIQGCRTAREAYRHFGKAPGVPHS TSAPYVRSKGRKFEQARSRRSSRGYKN--------------------------------- -------------------------------------------------VSRSRLGMPFI RDGATIRVVLELFKERFNVYLTEKSGVDMYNEVTALGIPATLILDAAVGYIMENVDLVLI GAEGVVESGGIINKGTYTMALSAKELGKPVYVVAESFKFTREFPLN-QDIPENFKYHSSK EHPLVDYTPPAYLXVLFTDLGVLTPSAVSDELIXVY-XXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKARGELLEYKIVGRSYPTEKCRV PPLYQMQIFAPNNTTAKSRFWYFANKLKKMKKSAGEIVCTSRVYEKKPCTVKNFGIWIRY DSRSGTHNMYKEYRDLTISGAVTQCYRDLGARHRARAHSVQIMKVQAIPSSKCRRAYIKQ FHDSKIRFPLTNRVKRPLHHPRFTTRRPHTTFXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--STNLSAYRDQHFRGSRGEQ EHLLATSTTLYLGNLSFYTTEEQIHELFSRCGDIKRIIMGLDKLKKTPCGFCFLEYYTRE DAENALRYVNGTRLDDRIIRTDWDAGFKEGRQFGRGKHGGQVRDEYRTDFDSGRGGYGKM VKEKIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX---------GDELASDCFPDVFYKFKLRDNFDIGANASMGFDCVLNSAKRFKAYFMT YLKELKELEIFSGLLVVHWSVPYGYLAMDGLTKKSSXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXMSIMSYNGAAVIAMIGKDCVAIAADRRYGIQAQTVSTDFQKIFEMGPRLYV GLPGLATDVQTVGQRLAFRLKLYELRENRRIKPKTFMSMVSNLLYERRFGPYFVEPVIAG LDPLTDKPFIASMDLIGCPMVTDDFVVSGTCSEQMYGMCESLWKPDMTPDELFEQISQAL LNAVDRDACSGWGGIVHVIEKTRL----------MTSKDYYFDSYAHFGIHEEMLKDEVR TLTYRNSMYHNKHLFKGKVVLDVGCGTGILSMFAAKAGAKKVIGIEMSSIVEHAEKIIAA NNLSDVITVVKGKVEEVSLPDGIEHVDIIISEWMGYCLFYESMLNTVLYARDKWLAPDGL IFPDRATLXVTAIEDRQYKDEKINWWDNVYGFDMSCI----------------------- ------------------------------------------------------------ ---------------------------------------------------------MVK EDRATWKSNYFMKIIKLLDEYPRCLLVSADNVGSKQMQSIRANLRILFGKNTMMRKAIRG HLENNPQLEKLLPHLKGNIGFVFTKAELTETRDRVLSHRVAAPAKAGALAPLDVTVPKQN TGLGPEKTSFFQALNIQTKITKGTVEIMNDVKLVTAGERVGASEAALLNMLKISPFSYGL VVEQVYDSGTVFNPAVLDITDDDLRAKFLEGVANVAAVSLAIGYPTAASAPHSIVNGFKN LLAISV--------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXARMVTKTIGGEKNGGTR TVRVNRLPRHYPTEDRRLKLKTAFSQHKRKLRASITPGTVLILLAGRHKGKRVVFLKQLK SGLLLVTGPYHLNGCPLRRINQTYVIATQTKLDCSKMNLPERLNDEYFKKKQLRRPKHTE GEIFETKKEEYAVSDERKQDQVEVDKQVLDVVRAHPDKKLMFGYLGSPFSLK-------- --LEWLFGRKKTPEEILRQNKRALDKAMRELDRERQNMERNEKKIIADIKKLAKQGQMDA VKIMAKDLVRTRRYVKKFILMRANIQAVSLKIQTLKSQNSMAQAMKGVTKAMQTMNKQLK LPEIQKIMMEFEKQSEMMDMKEEMMNDAIDDVMGDEDDEEESDAIVGQVLDELGLQLGDE LAGL-------------------------------XXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXDEPGARLLASKNILNQIIVEDKDVTVEYAVYNVGGSAAFNVILSDTSFPESSFEPVH GFLNVKWERVAPGNNVSHVVVLRPAKAGIFNFTSAELSYSPSEEETIKGYTSAPGHKEII PNKEYDRRFSPHFLDWAAFAVMTLPSLGIPFLLWFSSKSKYTSSKPKKNXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX >Lingula_anatina MSERKAVVKNADMSEDMQQDAIDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHAIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSGLASQIRSFQTSVSRRDIDQAAKYIGAGAATV GAAGSGAGIGSVFGSLVIGYARNPSLKQQLFSYAILGFAMSEAMGLFCLMMAFLLLYAF- -------KVTEAPIHRIRITLTSRNVKSLEKVCADLIKGAKEKSLKVKGPVRMPTKILRI TCRKTPCGEGSKTWSRYQMRIHKRIIDLHSPSEIVKQITSISIEPGVEVEVTIADXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX X---------------------------ELAEDGYSGVEVRVTPTRTEIIILATRTQNVL GEKGRRIRELTSVVQKRFSFPEGTVELYAEKVATRGLCAIAQAESLRYKLIGGLAVRRAC YGVLRFIMESGAKGCEVVV----------------------------------------- ---------------------------------------------------MSKRGRGGS SGGKFRISLGLPVGAVMNCADNTGGKNLYIISVKGIKGRLNRLPAAGSGDMVMATVKKGK PELRKKVHPAVVVRQRKSIRRKDGVFIYFEDNAGVIVNNKGEMKGSAITGPVAKECADLW PRIASNASCI-------------------------------------------------- ---KCKADRDEASPYAAMLAAQDVAEKCKTLGITALHIKLRATGGNRTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL-------------------------- ------------------------------------------------------------ ---XLNYIEENDEVLIAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKEKKERPRSEGA ATLRTRKFLTNRLLCRRQMIVDVLHPGRATVPKSEIREKLARMYKVTPDVIFAFGFKAQF GGGKTTGFALIYDSLDFAKKFEPRYRLIRHGARKQRKERKNRQKKVRGTKKAKVGA---- --------------------------------------------LVWVRKAARELLTLEE KDPRRLFEGNALLRRLVRIGVLDEGKMKLDYVLGLRQEDFLERRLQTQVFKLGLAKSIHH ARVLIRQRHIRVRKQVVNIPSFVVRLDSQKHIDFSLKSPYGGGRAGRVKRKNMKKGGGGG GD-------------------------------------------------------VEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVGEAREELNRMLAEDELRD AVLLVFANKQDLPNAMNAAEITDKLGLHSMRNRKWYIQATCATSGDGLYEGLDWLSNELK TK-MPLAKDLLHPSLTEEKRKHKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRRKAHMVRMNVLADALNTICNAEKRGKRQVLIRPCSKV IVRFLTVMMKHGYIGEFEIIDDHRSGKIVVNLTGRLNKCGVISPRFDVAIRDLEKWTSNL LPSRQFGYLVLTTSGGIMDQEEARR------------MVRMHAPGKGISQSALPYRRSIP TWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKAKGLAPD IPEDLYHLIKKAVAIRKHLERNRKDTDSKFRLILVESRIHRLARYYKSKKVLPPNWKYES ATASALVAVAEAPEIKLFGRWSSEDVQVSDISLTDYIAVKEKYAKFVPHSGGRYQVKRFR KAQCPIVERLTCSLMMHGRNNGKKLLAMRIVKHAFEIIYLLTGENPLQVVVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREAAFRNIKTIAECLADELINAAK GSSNSYAIKKKDELERVAKSNR------------------------------VLSASRDK SLIXWRLERDQNYGTTQKSLRGHNQFISDVVMSSDGQFALSGSWDGTLRLWDLNTGVTTR SFVGHTKDVLSVAFSADNRQIVSGSRDKSIKLWNTLGVCKYTIEDCHSEWVSCVRFSPNT HNPLIVSAGWDKQVKVWNLTNCKLKTNHYGHTGYLNCVTVSPDGSLCASGGKDGQAMLWD LNEGKHLYTLDGGDEINALCFSPNRYWLCAATGPSIKIWDLEGKIVVDELRQEVISTSAR PPQCISLAWSSDGQTLFAGYTDKLIRVWQVSITTRMREYKLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKQVEVDGNQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKLARAWNCAFLETSAKSK INVNEIFYDLVRQINKKNPHRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMAAIRKKLVIVGDGACGKTCLLIVFS KDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSI DSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDATTQRELQKMKQEPVRPEEXSS NGGKIGAFAYLECSAKTKEGVREVFETATRAALQVSKKKKRRXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------- ---------------------------------------------------------XXX RXXQXVVFIAQSVFXPKPTRKTRTKNXQKRPRSRSDSS-HDQSWIDLVLPXQ-------- ------------------------------------------------------------ ---------------KEWIPVTKLGRLVKDGKIKTLEEIYLFSLPIKEFEIIDFFLGSAL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDFNGHVGLGVKCSKEVATAIR---------- ------------------------------------------------------------ -----------------------------------------------------XXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXMKFNKMVTSSRRKNRKRHFNAPSHIRRKIMSAPLSKELRQKYNVRSIPIRKDD EVTVVRGHYKGQQVGKVVQCYRKKFVIYIERIQREKANGATVHVGIHPSKVVIVKLKIDK DRKRILERKARSRQVGKHTEESIASPSSTSVGSTVRQRKTPASMGSSAGMWRFYTEDSPG IKVGPVPVLVMSLLFIASVFMLHIWGKYTRGKGEKKKKSAISEVVTREYTVNVHKRIHGI GFKRRAPRAVKEIRKFAEKXMGTPDVRIDTRLNKHIWSKGVRNVPYRVRVRLARKRNEDE DSPHKLYTLVTYVPVASFKGLSTVNVDGSSKSEFIVGQKYRFLRKIGSGSFGDIYLGINI SNGEEVAVKLEPLKARHPQLLYESKVYKILQGGIGIPHIRWFGEKEYNTLVMDLLGPSLE DLFNFVSRRFTMKTVLMLADQMIGRIEYVHNKNFIHRDIKPDNFLMGIGRHCNKVFLIDF GLAKKYRDSHSRTHIPYREDKNLTGTARYASINAHMGIEQSRRDDMQSLGYVLMYFNRGS LPWQGLKAATKKQKYERISEKKMSTPVEVLCKGFPAEFAMYLNYSRGLRFDENPDYMYLR QLFRILFRTLNYQYDYTFDWTMLKQKAAA-MNPEKLKNRIGGKGTPRRKKKAVHRTATTD DKKLQSSLKKLAVNNIPGIEEVNMIKDDGQVIHFNNPKVQASLAANTFAINGHAETKQIT EMLPGILNQLGTEGLTNLKKLAEATDEIDDD------------------MVRYSLDPENP TKSAKAKGSHLRVHFKNTRETAQAIKRMHLRRAIRYLKNVVEKKEIIPFRRFNGGVGRHA QAKQFGSTQGRWPKKSAEFLLQLLKNAESNAEFKGLDTDHLVVEHIQVNRAPQMRRRTYR AHGRINPYMSSPCHIEVILAEREQAVAKTTKKKESKKKLKKQKM----KKGGPKAELTEE QKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKXMISDIDKDGSGTIDFND FLTLMTQKMSEKDSKEEILKAFRLFDEDGTGKISFKNLKRVAKELGENLTDEELQEADRD GDGEINEQEFLRIMKKTSLY---------------------------------------- ------------------------------------------------------------ IVQIDATPLRQWYEAHYCAPLGRKKGVKLSEQEEAALNKRSKKTQKKYDERKKVAKVEQA LEEQFMTGRVMAAISSRPGQCGRCDGYVLEGKELEFYLRKIKQKKGKMTLVLPEKFQHIL RVMNTNIDGKRKIAFAMTAIKGIGRRYSHVCARKADIDLSKRAGELSEEEVERMMTILSN PRQYKIPDWFLNRQKDVKDGKYTQVMSNSLDNKLREDLERLKKIRAHRGLRHYWGLRVRG QHTKTTGHRGRTVGVSKKK-SGTESDSDDDVPDLEEMAQAAGIKEELVSKAKQSRSEKKA RKAMAKLGLKHVAGVTRVTIRKSKNILFVINRPDVYKSPASDTYIVFGEAKIEDLSQQAQ VAAEQKFKAEEEVDDTGVEAKDVELVMSQANVSRSKAVRALKNNSNDIVNAIMMGRVRTK TVKKAARVIIEKYYTRLTLDFHTNKRICEEIAIIPSKPLRNKIAGFVTHLMKRIQRGPVR GISIKLQEEERERRDNYVPEISAIEEVDPDTKEMLKMLDFGNIPNLQVMQPISAA----- ---------------------------------------------VPSDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGALYQEHHEEDFFLYIAYSDESVYGMRELRIRKL CLNICVGESGDRLTRAAKVLEQLTGQQPVFSKARYTVRSFGIRRNEKIAVHCTVRGPKAE EILERGLKVREYELRRGNFSDNGNFGFGIQEHIDLGIKYDPGIGIYGMDF---------- ---------RIGAKHRVNKDEAMKWFQQKYDG---------------------------- ---------------------------------------------------------GIS PIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMVITIGQSIVYVMTGMYGEPSD LGAGVCLIIIIQLFVAGLIVLLLDELLQXGYGLGSGISLFIATNICETIVWKAFSPATVN TGRGTEFEGAIIALFHLLATRTDKVRGLREAFYRQNLPNLMNLMATVLVFAIVIYFQGFR VDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQL--------------- ----------------------------------DPIHAILYIVFMLGSWAFFSKTWIDV SGSSAKDVAKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVMADFMGAIG SGTGILLAVTIIYQYFEIFVKEQSEMGGMSTLLFQTERSFQKQPTVFLNKKRSLLLRYVK NVGLGFKTPREASEGHYIDKKCPFTGNVQIRGRILSGVVLKMKMQRTIVIRRDYLHYVRK YNRFEKRHRNMSVHLSPC------------------------------------------ XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------RKVVPSANRAMVGIVAGGGRIDKPMLKAGRAYHKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGKASTVRRDASAGKKVGLIAARRTGRIRGTKQITG KXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRRPARCYRYCKNKPYPKSRFCRGVPDP KIRIFDLGRKKANVNEFPLCVHLVSDEYEQLSSEALEAGRICANKYLVKFEGKDTFHIRM RLHPFHVLRINKMLSCAGADRLQTGMRG--GKATGTVARVHIGQPIMSVRAREGAKANVI EALRRAKMKFPGRQKVIVSHKWGFTKWPKEKFEDMRNQGRLDPDGVNVQYKPEKGPLSVW ----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XMTKGTSSFGKRHNKSHTLCRRCGRSSYHIQKKTCAQCGYPAAKIRKFNWSVKAKRRKTT GTGRQRHLKIIYRKFRNGFREGTTAKPRQK------------------------------ ------------------------------------------------------------ ----------------RYKERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDSQIFCLHGGLSPSIDTLDHIKALDRIQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHSNGLTLIARAHQLVMEGYNWCHDRNVVTIFSAPNYCYRF GNQAAI------------------------------------------------------ ------------------------------IGFRAKQGYVVYRVRVRRGGRKRPVPKGAT YGKPKTHGVNQLKFQRSLRNVAEERIGRRCGGLRVLNSYWVAEEATYKFYEVILVDPCHK GIRRDPKINWICKAVHKHRELRGLTGAGKNSRGLGKGHHFTKTIRRSHVVPTEKHN---- ----GIAFGRLAEERKAWRKDHPFGFVAKPVKNPDGSLNLMNWECAIPGKKGTIWENGLY KLRMLFKDDYPFSPPKCKFEPPLFHPNVYPSGTVCLSLLDEEKDWRPAVTIKQILLGIQE LLNEXTLKDPAQXEAYTIYCQKKA------------------XXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXX-------------------------------------------------------- ------------GLRDGYYIQGQCAIIMFDVTARVTXKKCPNWHRDLVRVCENIPMVLCG NKVDIKDRK-KKKTNVFHRKKNIQYYDISAKSNYNFEKPFLYLARKLVGDPNLEFVAMPA LQPPEVTMDPSIAKQYERELEMAQATALPEDDEDIXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXX------------------------------------------------------- --------------------------------KDKVKALFKSSPDEGQAMKFTKNIFSGG AAGAMSLMFVYSLDYARTRLANDAKGSAKRQFNGLIDVYAKTLKSDGIVGLYRGFVISCV GIIVYRGFYFGLYDSLKPLLLGKDAGVFISFLLGYVVTVTSGLLSYPIDTIRRRMMMTSG QAVKYKGSIDCGRQIIANEGFMSLMKGAGANILRGVAGAGVLAGFDKFKAVYIKFRLXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXMVRGPRKHLKRLHAPKHWMLDKLGGTFAPRPSTGPHKMRECLPLMIFLRN RLKYALTYDECKRIVAQRLIKVDGKVRTDFLYPAGFMDVITIEKTGEHFRLIYDVKGRFC VHRISAEESKYKLCKVKHVKVGPKGVPFIVTNDGRTIRYPDPLIKANDTVQV-------- ------------------------------------------------------------ ----------------------------------ERWLKELRDHADNNIVIMLVGNKSDL RHLRAVPTDEAKAFAEKHNLSFIETSALDSTNVEAAFQNILTEIYKIVSQKQIRDSPDDN DVRTIQVAPTDNSQPKKQCC--MSSTYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVR GNDIVVLGVEKKAVAKLQEDRTVRKXALLDDHVAMAFAGLTADARILINRARIECQSHKL TVEDPVTLEYITRHLAQLKQRYTQSNGRRPFGLSTLIIGFDGTPHLYQTDPSGTYHEWKA NAIGRSAKTVREFLEKHYTDDTASEHDTVKLALKALLEVVQSGGKNVELAYMKFGQPLKM MESAEVEKYIAEIEKEKEEEAEKKKQK-------------------------------KV KGPDAAMKLPQVTPHTRCRLKLLKLERIKDYLLMEEEFLRNQERLKPQEEKQEEERSKVD DLRGTPMSVGNLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDALEPGCSVLLNHKVHAVI GVLSDDTDPMVTVMKLDKAPQETYADIGGLDQQIQEIKESVELPLTHPEYYEEMGIKPPK GVILYGQPGTGKTLLAKAVANQTSATFLRVVGSELIQKIIGXAPKLVRELFRVAEEHAPS IVFIDEIDAVGTKXYESNSGGEREIQRTMLELLNQLDGXNXRGDGKVVMATNRIETLDPA L----------------------------------------------------------- ------------------------------------------------------------ ------------------GLACCAVEMMHFAAPRYDMDRLGMVFRASPRQADCIIVAGTL TNKMAPALRMIYDQMPDPRWVVSMGSCANGGGYYHYAYSVVRGCDRI------------- ---------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMVAQKKTKK ALENINSRLALVMKSGKYVLGYKQTLKTLRQGKAKLIIIA-------------------- ------------------------------------------------------------ ----------------------------DGESCLLDIXDTAGQEEYCAMRDQYMRTGEGF LCVFAVNNEKXFEDINQYREQIKRVKDADEVPMVLVGNKVDLPSRTVDTKQAGGVADSFG IPYVETSAKTRQGVDDAFYTLVREIRKYMGDRYNIHSQLEHLQSKYIGTGHADTNKWEWL TNQHRDSNASYMGHFDXLNYFAIVGNEAKARVKFNXMERMLQPCGPPPERPEDMKLELCA FSGYKIYPGHGRRVVKADGKVTIFLNAKCERSHLMKRNPRKINWTVLYRRKHKKGQTEEV SKKRTRRTAKFQRAIAGTSLTDIMAKKNQKPEVRKAQREQAIRAAKENXRAKDKSAPRVG GKRMKLNISFPATGCQKLIEVDDEKKIRAFYEKRMASEVSAESLGDEWKGYVVRISGGND KQGFAMKQGVLTNGRVKLLLGKGQSCYRERRSGERKRKSVRGCIVDS------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------KXCVVRRNVPRVLTVINQTQKENL RKFYKPKDLRKRQTRAIRRQLTSRELKLKTKKQQRKERLWPMRKYAVK-------VTKAA YFDIEIGXEKAGRIEIGLFGNNVPKTVENFAQLSSGQ-GYKGSKFHRVIKDFMIQGGDYD KGDGTGIKSIYFDDENFDIEHYGAGWVSMANAGKDSNGSQFFITTVKTSWLNGKHVVFGV VTKGMSVVRKIENSKTDKDKPETDV----------------------------------- ---------------DKYLQERIKVNGKTGNLKNKVVVTSDIPLSKRYMKYLTKKYLKKN NLRDWLRVVASSKDTYELRYFQINNEEEEEEEAE-----------YGGCEGPDAMYVKLV SSDGHEFIVKREHALTSGTIKAMLSGPGQFAENETNEINFREIPSHVLQKVCMYFTYKVR YTNSATEIPEFPIAPEIALELLMAANFLDCTEVIPLEQVLIKNKEGQTWIIIGHKVYNVT EFKEQHPGGAQVILDEAGKDATRAFHDVGHSADAEELMK--------------------- --------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX--------------------------------------------- ---------------LSGKDVIAQAQSGTGKTATFSIAILQQIKLEXEECQALVLAPTRE LAQQIQKVVIALGDYLQAQCHACIGGXNVMEDVRRLEYGVHVVVGTPGRVFDMIKXETLN PAYIKLFVLYEADEMLSRGFKDQIYDVFQFMPSTIQVILLSATMPADVLEVTXKFMRDPI RILVKKEELTLEGIKQFYV----------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------SNTKAVAQVPRVGI GMDACVTPLRHGGLSLVQTTDXFIPLVDDPYMMGRIACANVLSDLYAMGVTECDNMLALL AVSNKMGDKERDVVVPLMLTGFKDLAEEANTQVTGGQTVINPWMTIGGVATTVCQPNEFI MPDNAVIGDVLVLTKPLGTQVAVNAYQWLDQPERWNRIKLVVSEEDVKKAYQRAMFSMA- ------------------------------------------------------------ ------------------------------------------------------------ ------------IFISLLSYINCYFVSIDANAEECYFERVKPGTKMSLMFEVAEGGFLDI DVKITGPDGREIYSGDRESNGKYTFSAHMEGVYKYCFSNRMSTMTPKIVMFSIDVGDQPG AQHTKLEEMINELSTALTGVKHEQDYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMT LGQIYYLKRFFEVRRVVMSATLRPYLSAVRQTLTAALCLENFSSQVVERHNKPEVEVRXS KELLLTPVVISRIEKEKXLIEGSVNSLRLI-------EIEKXFCHNLMIFMMMRAEIFVL LRXKPVAGYDISFLVTNFHTEQMYKHKIVDFIIQFMEEIDKEISEMKLAVNSRARISAEE FLKRFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------- ---------------------------------------SFKYAWVLDKLKAERERGITI XIALWKFETSKYEVTIIXAPGHRDFIKNMITGTSQADCAVLIVASGTGEFEAGISKNGQT REHALLAFTLGVKQMIVGVNKIDSTEPPYSEARFKEICTEVSNYLKKVGYN-KLLPXVPI SGWHGDNMMNMSWYKGWAIAKGMTLLEALDSILPPQRPTDKPLRLPLQDVYKIGGIGTVP VGRVETGILKPGMVVTFAPAMLTTEVKSVEMHHESLTEALPGDNVGFNVKNVSVKEIRRG FVCGDSKSDPPQETAEFKAQVIVLNHPGQINAGYAPVIDCHTAHIACKWSELQEKIDRRS GKKLEDNPKFLKSGDAGIVNMIPSKPLCVEAFSNYQPLGRFAVRDMRQTVAVGVIKETKK KE-NTGKMTKAAEKAELEQLRQEAEQLKNQIRDARKNACDTSLAQAAANVEPVGRIQMRT RRTLRGHLAKIYAMHWATDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAP SGSFVACGGLDNICSIYSLKTREGNVRVTRELPGHTGYLSCCRFIDDNQIVTSSGDMTCA LWDIETGQNTTTFAGHTGDVMSLSLAPDMRTFVSGACDASAKLWDTRDGMCHQTFTGHES DINAITYFPNGYAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLG GYDDFNCNVWDTLRQDRAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKIWNMSYAYLF KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES FRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSSSNMVIMLI-NKSDLEARR DVKKEEGEAFAREHGLIFMETSAKTAANVEEAFINTAKAIYEKVQEGVLDINNESNGIKL GPQHSPSSPSGGSGGNQGGGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPRQ IMEIKDFLLTARRKDAKSVKIKKNVKFKVRCTKYLYTLVIQDREKAEKLKQSLPPGL--- -------SLSTLTDAVNEILRKKRKFTESVELQIALKNYDPAKDKRFSGTVKLKHIPRPK MRVCMLGDDAHCDEAKANDIPSMNADDLKKLNKNKKLVKKLAKKYDAFLASDSLIKQIPR LLGPGLSRAGKFPTLLTHSEPMTGKVEEVKATIKFQMKKVLCLAVAIGHVNMAPEELVAN LNISINFLVSLLKKNWQNVRALYIKTSMGPSQRIYMADADKLNIDSIIARLLEVRGSRPG KNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFTHES NYLLLXDYVDRGKQ---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------VDETLMCSFQILKPADKKKFTYGGLNAGRPVTPPR------ ---MFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEIVGTNVSTT YITCPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPF ICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDEL PAEFKLYLPVQKK-----IQNLKDPFGDASKIHIRIQQRNGRKTLTTVQGLSTVYDLKKI VKACKKEFACNGTVVDHPEYGEVIQMQGDQRNHVRDFLKSMGLEDQIKVHGFSALFNFQS LLTVILLMICTCAYVRSMAPRLLDKNKEGLLGIFWKCARIGERKSPWVAVCCVAMAFSIL FWS--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------YLHSRLLERAAKMNDNFGGGSLTALPVIE TQAGDVSAYIPTNVISITDGQIFLENELFYKGIRPAINVGLSVSRVGSAAQTKAMKQVAG RMKLELAQYREVAAFAQFGSDLDQSTQNLLNRGVRLTELLKQGQYVPMAIEEQVAVIYAG VRGHLDKMDPSRITAFEEEFLAHIRATQKELLTVIKNEGRITDATDAKLKDVVTSFLAGF ------------------------------------------------------------ ----------------YRVNGQYIMEGLASSFLFTMGGLGFVILDQTNSPLTPKLNRILL LVVGFVCILISFFMCRVFMRMKLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEYAQVTKMLGNG RLEALCFDGVKRLCHIRGKLRKKVWINGGDIILLGLRDYQDGKADVILKYTPDEARNLKA YGELPETAKIND--------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPLLIDARGHLLG RLASIVAKTLLQGQRVVVLRCEGINISGNFYRNKLKYLEFLRKRTNSNPSKGPYHFRSPS KIFWRTVRGMIPHKLTRGKDAMDRMKVFEGIPPPYDKQKRMVVPAALKVLRMNPRRKFCN LNRLSHEVGWKYQGVVATLESKRKVKARSYYDKKKAEGKMKAQATKGADLQKTVESMGY- -----------RKCSQCHTLNKDQPHKTGPNLYGLFGRQTGQAPGFAYTDANKSKGITWA RETIFEYLENPKKYIPGTKMIFAGIKKPGARGDLIKYLEVET-XXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXX-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------QILDPNVVGEEHYEVARGVQKVLQDYKSLQDIIAILGMDELSEED KLTVSRARKMQKFLSQPFQVAEVFTGTEGKLVPLSETIKGFKQVLNGELDHIPEVAFYMT GTVDEVLVRADELAEEQMLMPKKARIAVYEHLFKEGVMVARKDFIAPKHPELDVRNLYVI KAMQSLKSRGYVNEQFAWRHYYWYLTNEGIQYLRDFLHLPPEIVPSTLK----------- -----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXMSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNL TGLNEQVPHYRQALDMILDLEPDDELEDNPGTSDLIEQAAEMLYGLIHARYIMTNRGIAQ MIEKWQQGDFGYCPRVYCENQPMLPIGLSDVPGEAMVKLYCPXCQDVYTPKSSRHHHTDG AYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGF-------------------------- MTNTKGIRRGTRYMFSRKFRTKGAIPLSTYFKTYRRGDIVDIKGNGAIQKGMPHKIYHGK TGRVYNVTPHAVGIIVNKRVRGRIIAKRINVRIEHIRHSACRVDFLNRVHENEK------ -------------------------------------QKRTAYKVVTRRHFE-TLKDQTT NVARRLFFTELMRGLLIGVSWFFREPATLNYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAICPAQAITIEAEEREDGSRRXTRYDIDMTKCIYCGFCQEAC------------- -------------------------------------XXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX------------------------------------------- ------------------------------------------------------------ ---------------------FSIFYNNSLYLVLIILASFYLLRTFNPTVNYIVSVLAAG GLLALFSTST--------EVKVCLLGESGVGKSSIVLRFVSDTFKQGLEMTIGASFMTKT MVVDQQTVKFQIWDTAGQERYRALAPMYYRGASAAIVVYDVTKRDTFDAVKGWVRELANY GPKDIIIALAGNKSDLREVTKKEAAQYAEQIQAIFIETSAKNDSGIKELFTNIISRLP-- ------------------------------------------------------------ ------------------------------------------------------------ FVREEDAEKAVADLXHRWFNGQPVRAELXPVTDFREACCRQYEXGECTRGGFCNFMHLKP ISRELRRKLYGRRRRSRSRSPGGR---------GDRRSRSRDRDR--------------- ------------------------------------------------------------ ---------------------------------------------LAFGDDDADPGXMSR PFGVALLFAGIDDKGPQLFHMDPSGTFIQYDAKAIGSASEGAQQTLXEVYHKSMTLKEAC KKCLNILKQXMEEKLNSKSRSWTTVTPAAGYKLFSKEEIE-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------VHCKQYYSLDVSYFKSGLDRRMLESLWNKYWVNTLSSSSLLTNADYT TGQIFDLADKLEQSEIQLGRGGFMDKKAEDKLTKATKEGXKNTMESIHGLMSQVIK---- ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPCFADLG KDARDVFSKKYNFGFFKIETSTKTKSNVEFKVEGSSNHDTGNVFGTFETKYKWADPGITV KEKWNTDNMLSTDITIEDQLLEGLKLTLDGSFAPVSGKKSAKIKAAYKRDYINLNCDVDL GFAGPTVHGAAVLGYSGWLAGAQISFD---------AAGYKKDDFQIHTTVTDASEFGGS LYQKISKDLETAVSLNWSSGTNTTRLNLGAAYTLDNGAKVRAKVNNLSQIGMAYSQELRD GVTLNLSSMIDAKNFNSGGHKVGLGLEFE------------------------------- ------------------------------------------------------------ ---GTRVXLDMTTLTIMRHLPREVDPXVYNMSTEDPGKVNYSEV-GLGEQIRELREXIEL PLLNPELFMRVGITPPKGCLLYGPPGTGKTLLARAVASQIEANFLKVVSSAIVDKYIGES ARLIREMFAYARDHQPCIIFMDEIDAIRRFSEGTSADREIQRTLMELLNQMDGFDALGQV KI---------------------------------------------------------- --------------------------------------------------------MPES LGSVIGKFYDQYMQDTPKKLKLVDAYLLYILLTGVVQFAYCCLVGTFPFNSFLSGFISCV GSFVLGVCLRIQVNPQNKHEFNNLAPERAFADFIFAHIVLHLVVMNFIGXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX--------------------------------------LKIDENG KIVDAKFKTFGCGSAIASSSFATEWVKGKSVDDASSIKNTEIAKELSLPPVKLHCSMLAE DAIKAALSDWKKKNDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXERSFIMVKPDGVQRGLVGEIVKRFEQRGY TLRAMKMMHASKPHLEEHYKDLSSKGFFKDLVAYMNSGPVVAMVWEGDAVKTGRKMLGET NPLASAPGTIRGDFCIEVGRNICHGSDSVESANREISLWFKPEEIIAWDPCIKDWIQEXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----------------------------Q EEDKYPVGPWLIALFVFVVCGSAVFQIIQSIRFXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMIRFI LIQNRAGKTRLAKWYMHFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIVYRRYAGL YFCICVDVSDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYSVVDECXWQEKFVE TSQTKVLKQ----------TIFGKITRGEIPCKFIHEDDKCVAFHDLSPQAPIHFLVVPR KPLSQLSGDKEMLGHLLLVAKQVAKEEKGFRLVVNDGAEGAQSVYHLHIHMMGGRQMGWP P----------------------------------------------------------- ---------------------------------------------------EEEELKKSI LVVLANKQDIEGAMTVSEVANALGLSTIKNRKYQIFKTSAIKGEGLDESMEWLSNILQ-- ------------------------------------------------------------ -------------------------CLHSNSSAWFGGGQLRVHLDIQVGEHANDYPQIAT KDKLTELQLRVRQLLDQVEQITKEQNYQRYREERFRQTSESTNQRVLWWSIAQTLVLLVT GFWQMRHLKGFFEAKKLV------------------------------------------ ----------------------------------------------VTQVNKVGLFVEIG PLSCFISRHCIPGDMEFDPNSNPPCYKXKDEDMVIQQDDEIRVKVIGTRVDATDIFAIAS LMDDYLGLVSRLYVKAVFTGYKRGLRNQHENTSLLKLEGVTTKKATEFYLGKRCCYVYKA KNKSACPGHDKASRIRVIW-----------------------------------XXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXMAARPLITVYSEKAEPSESNITLPAVFRAPIRPDIVNFVHAEIRKNARQAYSV NEYAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRR VNVNQKRYAICSAVAATGIPALVMSKGHRIEEIPEVPLVVSDKVQEYKKTKEAVGLLKKL KAWADIQKVYNSKRFRAGKGKMRNRRRIQRRGPLVIYNQDNGITRAFRNIPGITLINVSR LNLLKIAPGGHVGRFCIWTESAFRKLDALYGTWRKASKEKSNYNLPMPKMTNSDLSRLLK SDEIQRVVRPPQRNNKRRVLKKNPLKNIRVMQKLNPYAAVMKRNALRKKAKQAAINKKRG IA---------------GSSEQELATKTLQIQSKRFYLDVKQNRRVRFIKVAEVGAGGKK SRLLLAMSTAAEFRDHLTEFSEHYASLGPASTDNLPEDGKLKSETMVKDNRRYYLDLKEN ARGRFLRVSPRGGPRSQIAIPAQGMIEFRDALTDLLDEFGTDDHEPAGDLPESRSLRTEN KVFYFDVGHNRRGVFMRVSENSFRTAITIPERAWTRFRDIFNEFLEKXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXMNIRNAMPQDLMNMQHCNLLCLPENYQMN-YFYHG LSWPQLSYVAEDEGGK-CRLCISKNEEDPEDSVPHGHITSLAVKRSHRRLGLAQKLMDQA SRAMVECFNAKYVSLHVRKSNRAALNLYQKTLKFNISEIEPKYYADGEDAYAMRRDLSEF SDK-MSHTILLIQPTKKPDSRTYSDYESINECLEGICKIYEEHLKKAHPQSPSITYDISQ LFDFIDQLHDLSCLVFQKSSTTYCPRNKDWIKEKIYIMLRKQAGK--------------K --HTYPLIRHSDMQDEMRVEAMELCVTACEKFSTNNETAAKMIKEPMDKXFGPSWHVVVG EGYGFEITHEVKNLIYMFFGGNVAITLWKCSMSHRKFSAPRHGSLAFLPKKRSVRHRGKV KAFPKDDPSKPVHLTAFLAYKAGMTHIVRDVDRPGSKTNKKEVVEGVTILETPPVVVVGV VGYIETPRGLRTFKTIFAEHLSEECRRRFYKNWYKAKKKAFTKYAKKWQDEDGKKAIEKD FEKMNKYCKVIRVIVHTQMKLLKKRQKKAHIMEIQLNGGSISEKIAWAREHMEKQIVVSQ VFSQDEMIDIIGVSKGKGYKGVTSRWHCKKLPRKTHKGLRKVACIGAWHPARVGFSVARA GQKGYHHRTEINKKIYRIGQGIHTKDGKVIKNNASTEYDITEKSITPMGGFPHYGEVNND YMMVLGATVGPKKRVLTLRKSLLTHTKRKALEKISLKFIDTSSKFGHGRFQTHEEKRNFL GPLKKDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXX----------------------------------KKKKKKPL DMDELSEALPENEDLSTKKKKKLDSERDYTYDELLTRVFDIMREKNPDMVAEKKKK---- ------------------------------------------------------------ ------------------------------------------------------------ --------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------------------- ------------------------NFYVPAEPKLAFVMRIRGINGVHPRPRKIMQLFRLR QINNGVFVRLNKATVNMLRIAEPYLAWGYPNLKSVRELIYKRGYGKVNGKRIPLTDNEII EKQLGQYGIICMEDLIHEIMTVGPNFKQASNFLWPFKLN--------------------- ------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSKAHPPELKKYL DKRLSLKLNGNRTVTGILRGFDPFMNLVIDESIEETKGGEKNNIGMVVIXGNSIVLLESL DRIEFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTI RLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFQQTSKWIDDVRTERGSDV--- ------------------------------------------------------------ -----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMTTMNPEYDYLFKLLLIGDSGV GKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGK------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------EEDGANIDLDSQRKGKCAVIKTSTRQTYFXPVIGLVEAEKL KPGDLVGVNKDSYLILETLPQEFDSRVKAMEVDERPTEQYSDVGGLDKQIQELIEAVVLP MTHKDRFTALGIQPXKGVLLYXPPGTGKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGA KLVRDAFALAKEKTPAIXFIDELDAIGTKRFDSEKAGDREVQRT-LELLNQLDGFHPTSE IKVIAATNRVDILDPALLRSGRLDRKIEFPLPTEDARARIMQIHSRKMNVSSDVNFEELA RCTDDFNGAQCKAVCVESGMLALRREATELSHEDYMDAILEXQAKKKANLQYYAXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXX--------------NNMLYPKEDKENKILAYACRNCDYQQX ADNPCIYVNKITHEVDELTQIIADVIADPTLPRTDDHPCPKCGHKEAVFFQSQTTKTEQG MRLYYVCTNNNCTHRWTEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXX-----------------------------EGIKIIPNEEDITDIQAAIEGPAG TPYAGGMFRXKLVLSKGFPSEPPKGFFXTKIFHPNVAKNGEICVNTLKRDWKTEYGIKHI LLTIKCLLIVPNPESALN------------------------------------------ ------------------------------------------------------------ --------------------------------------EGLCKFGFYEVFKXFYGNLLGE ENAYLWRTSLYLAASASAEFFADIALCPMESVKVRIQTQPGWSTTLREGFPRIMKDEGMN GFYKGLVPLWARQIPYTMMKFACFERTVEALYKYVVPKPRSECTKPEQLVVTFAAGSL-- ----XIXHXXPXXXXI------XXXIXXXQCLGLLGMWKGLFPRIIMIGTLTALQWFIYD SVKVYFRLPRPPPPEMPESLKAKLAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------------------- ------------------------------------------------------MKNPMT DPSMMTDMLKGNVTNVLPMIVIGGWINWAFSGFLTTKVPFPLTFRFKPMLQRGVELISLD ASWVSSASWYFLNVFGLRSMYNLILGQDNAADQTKVMQDQMSGAAMAMPQDPAKAL---- --------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--- -----------------------------------------------LKKVIQWCTYHKD DPPPPEDDENREKRTDDISSWDVEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMI KGKTPEEIRKTFNIKNDFTPAEEEQVRKENEWCEEKXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSVSALYI LDAKGKVMISRNYRGNXDSNVIDKFMTLLMDIEEDGSTTPILIHGNAAYMYIKCNNLYIV ALSKKMPMWHWSF-FLHKIVSVFTEYFKELEEESIRDNFVIVYELVDELMDFGYPQTTDS KILQEYITQEGHKLEVAPRPPMAVTNAVSWRSEGIKYRKNEVFLDVIESVNLLVSANGNV LRSEIVGAIKMRVFLSGMPELRLGLNDKVLFESTGRGKSKSVELEDVN-SQCVRLSRFEM IAPLXFIPPDGXFELMSYRLNTHVKPLIWVESVIERHAHSRVEYMIKAKSQFKRRSTANN VEIIIPVPADADSPKFKTTTGSCKYVPETSSVVWTIKSFPGGKEYLMRAHFGLPSVESED SEGKPPISVKFEIPYFTVSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRT------- ------------------------------------------------------------ --------------------------------------------------PGIIEGAKDG KGRGKQVIAVARTCGLIFIVLDVLKPLQHKRLIEHELEGFGIRLNKTPPNIVFRKKEKGG INLQQMVPQSELDADVVKTILAEYKIHNADITLRYDATPEDLIDVVEGNRVYIPCIYVLN KIDQI------------------------------------------------------- -----------------------------------------------------------X XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------- ----------VPANRYTPLKENWMKIFTPIVEHLHLQIRFNLKSRNVELK---------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------VKCATITPDEERVEEFKLKKMWLSPNGTIRNILGGTVFREPILCKNIPRL VPGWTQPIVIGRHAHGDQYKATDFVAEGNGKLTMTFTPENGSPVNMEVFNFKNGGGVGMA MYNTDESITGFAHACFQYAIQKKWPLYMSTKKKL-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------KNVKLNVWDVRGPXKIRPLWR HYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMKPHEI QEKLGLTRIRDRNWYVQPSCATTGDGLYEGLTWLTSNHKS-------------------- ------------------------------------------------------------ ----DDDDDFELFGSAAEKLKQERLEAYAAKKSPAVIAKSTVVLDIKPWDDETDMAELEK SVRSVAMDGLVWGASKLVPVGYGIKKLQIMCVIEDDKVSTEDLEDQIREFEDFVQSTDIV AFNKVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------VLKDLVKVI QQESYTYRDPITEFLECLYVNFDFDGAQQKLRECESVLVNDFFLVACLDDFIENARLFIF ETFCRIHECISINMLAEKLNMTPDDAERWIVNLIRGARLDAKIDSKLGHVVMGTQAVSPY QQVIDKTKGLSFRSQMLAMNIEKKLSAK-------------------------------- -----------------------------DEGVTEMSLGEKDKLTCSPDYAYGAKGYPGV IPPNATLIFEVELLSLEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX-----------------------------ALQKVLQSEFCQAV REVYEHVYETVDIQGSPEIRANATAKATVAAFAASEGHAHPRVVELPKTEEGLGFNVMGG KEQNSPIYISRIIPGGVADRHAGLKRGDQLLSVNGVSVEERIIEKA-------------- -------------------------LAALFCAALSEPTIYFEETFWEKRWVESTHKGAEQ GKFVHSAGKFYGDAEKDKGIQTSQDARFYGLSAAFDK-FSNEGKTLVIQFTVKHEQNIDC GGGYVKVFPSTLDQGDMHGDSPYNIMFGPDICGPGTKKVHVIFNYKDKNLLVNKDIRCKD DVMTHLYTLIVRPDNTYEVKIDNEKVESGKLEDDWNFLPPKKIKDPEAKKPDDWDEREKI DDPDDTKPEDWDKPEHIPDPDAKKPEDWDDEMDGEWEPPMIDNPDYKGEWKPKQIDNPDY KGKWVHPEIDNPEYTPDENLYKYDDIGAIGFDLWQVKSGTIFDNILITDDEDHAKKVGDE LWGVTKEAEKKMKDKQDEEERKKREEEEKKAKEEEDKKDEDEEE---------------- --------------------------NLYNKTHRANAEIIMFEGLTCVYRSNVDLYFFVV GSSMENELILASVLNTFYESVSQMLRKNVEKRALLDNLDGAFLALDEICDGGIILEADST AVCQRVAIKNDDIPLGEQTVAQV--------------XXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMA GSALKRLMAEYKQLTLNLPEGIVAGPINEENFFEWEALITGPEGTCFEDGIFPARLIFPP DYPLSPPKMKFTCDLFHPNIYPDGRVCISILHAQGDDPWVSETSXERWSPVQSVEKILLS VVSMLAEPNDESAANVDAAKTWRENKTEFEEIARRTVRKSLGLXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXX------------------------------LYRFLARRTNA KFNKVVLKRLFMSKINRPPLSIARLVRLMKKPGRDNKMAVCVGTITDDLRLLEVPKLRVC ALHVTSGARARILKSGGEIITFDQLALKAPKGQNTVLVQGPRKAREACKHFGPATGVPHS HTKPFVRSKGRKFERARGRRKSRGYK-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRSPEAVEGRKHIDVQT ELYLEELSDRVEEADVDCQTDAFLDRPPSPMFIPAKTGVDIATQILEGELFDFDIEVKPI LEVLVGKTVEQSLLEVMEEEELANLRSQQRSFEELRNAELVEQQRLEEQERRHREEKERR MKQQREILRKKK------------------------------------------------ ------------------------------------XXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-AQGEMLDFWKKNEKRPISPLTIWRSQL PMTLSFFHRFTGVAMICATYVFSWVMLASPVDYQWYITFLKDLH---------------- -IYHCINGVRHLAWD------------------------XXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMKLFRDVVSGDELLTDALPGCVYQVEAKSDALIGGNKSWKLNVVSASKKDYQTHIKT YMKKIEELEFYTGVVLKEYEVPVFYFFKDGLSEEKLXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------- ------------------------------------------------------------ ----------------------------------------------------FLTADKKK KYETKCTVXTLNPVFNETFMFKVPFADVACKTLVMAVYDFDRFSKHDQIGKVEVPLNSVD LGQVLEEWRDLQSPDSD-EKENKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSD PYVKIALY-QGQTHKEKKTNIKKKTLNPYXKRSLHSKFHWNRS-RSDLDHHHVDYDRIGT SEPIGRTVLGCTATGAELXHWXDMLANPRRPLQQVDTL-------MVLADLGRKITNALR SISNATVINEEVLNSMLKEICTALLEADVNIKLVKQLRENVRAVIDFDEMAAGLNKRRMI QSAVFQQLVKLIDPGVKAWQPTKGKNNVIMFVGLQGSGKTTTCTKLAYYYQRKGWKTCLI CAD--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMVK EDKSTWKSNYFLKLIQLLDEYPKCFLVGADNVGSKQMQQIRRSMRVLMGKNTMMRKAITG HMSNNPSLERLLPHIRGNVGFVFTKEDLNETRDLILSNKVPAAAKAGALAPVDVRIPAQN TGLGPEKTSFFQALSIPTKISKGTIEILNEVHLIKVGDRVGASEATLLQMLKIFPFTYGL IIEQVYDSGTVFSPEILDIKPEDIRKTFMEGVRNIAAISLEIGYPTAASAPHSIINGFKN LLAIAVETDYSFPAAETVKEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXGNETSLPLELCSTFDADEIKRLGKRFKKLDLDNSGSLSVDE FMSLPELQQNPLVQRVIDIFDEDGNGEVDFKEFIQGVSQFSVKGDKESKLKFAFKIYDMD KDGFISNGELFQVLKMMVGNNLKDTQLQQIVDKTIILADQDGDGEISFDEFSAIVGGMDV HKKMVVDVMTYLTSWDEFSKAAERLYISDPNKCRFVVKYRHCDGKLNIKITDDQVCLQYR TEHSQDVKKLEKLTNQLMRHMASKEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMLSSLLREHQARQ QARKEEQEKKRKEAYEATAFTHALVDHLNAGVAQAYVNQKKLDTETKILQINAGQFAKQT MQWLKLVEDFNTALKEIGDVENWARSIETDMRTVSSALEYAYK----------------- ------------------------------------------------------------ ---------------------------TKTKIDISKVKIPDNVNDEYFRRKKLKKPKHTE GEIFDTQKEVYAVSEERKKDQVDVDKQVLDAIRQSPDKKLLFGYLGAMFSLKNRQYPHEM QF---------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------SDAIVGQVLDELGLQIADE ISGLPTANQTPSKQPQGVSEADADLEARLENLRRQXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------- --------------------------------FEQFIPILQTVMKTQDTTTAEDFIEGFK VFDKDQNGFIGSAELRHLLSSLGEKLSDEEVEQLLQNMEDSQGNVNYEEFVKMVMAGXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXALILIGLYYCLSDQGYRFDIGWFLSTTSPVMWGGLGVAFAIALS VVGAAWGIFVTGSSINGAGVKAPRIRTKNLISIIFCEAVAIYGIILAIVMQNIANHKAGY QLFGAGLTVGLCNL---------------------------------------------- -----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGASQTFPMQCSALRKNGHVMLKGKPCK IVDMSTSKTGKHGHAKVHLVRHNITRXKKYEDICPSTHNMEVPNVSRKDYQLVDVTDGFL SLMEDDGNTRDDLKLP-------------------------------------------- ----------------------------------------------VQVYSRGQQVTTMG Q-----GLLELPLGITLNRQGHVMVCDSRKKSIFTFHADGQLLNTIPCETPVYITVNVND NIVISDLWGHCVHVLSPTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXKTEPKKVVNPLFEKRAKNFGIGQDIQPKRDLSRFVRWPKY IRLQRQKAILQQRLKVPPSINQFKQALDRQTATQLFRLMDKYRPETKQQRKQRLQARAEE RVKGKDDTPTKRPPVVRSGVNTVTTLIEQKKAQLVVIAHDVEPIEIVLFLPALCRKMAVP YCIVLGRVVHRKTCSCLALTLVNPEDKSALNKLIDAVKTNFNERGDEIRRHWGGGVMGAK SQARVAKIEKAKAKELAQKMRYVAAYLLAALGGNHSPSAKDLXKVLGSVGIEADAALMKK VIEELKGKDLKELIEKGSEKLASVPSGGGAAAEEKKKEEESDEDMGFGLFD--------- ------------------------------------------------------------ ------------------------------------------------------------ --------QNVILPVPAFNVINGGSHAGNNLAMQEFMLLPSGASSFSEALRMGSEIYHXL KSVIKKKYGQDACNVGDXGGFAPNIQDNKEGLELLKTAIELAGYTGKVVIGMDVAASEFY KKYDLDFKNPNSDKSKWLTSDQLNALYTDFTTNYPIESIEDAFDQDDWAAWAKMNA---- ------------------------------------------------------------ ---------------------------------------------------------PKS AGSLTTRPTKPTNFRKFYERGDFPIALEHDTKGNKIAWKVEIEKLDYHHYLPLFYDGLCE TVHPYEXLSRQGVHDMHEHGGSKILPVIPQLIIP-------------------------- -NMIGEALVPYYRQILPMLNLFKNNNLNSGDGIDYSQQKRENIGDLIQETLEHFERQGGE DAFINIKYMVPTYESCMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXDDHRRKWDKDEFERLARERLEEELEKDDKPVKRELLKPRDYRVDLEG KLGRSQVITKTTPSSQQGGYYCNVCDCVVKDSXNFLDHINGKKHQRNLGMSMKVERSSLD QVKKRFELNKRKRRKIXKSNDFEERMKELKKRRRXRKLQKREK----------------- --------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXMALKAVCVLKATDVIGTVYFEQTSACKVTGEVTGLKEGLHGFH VHQFGDNTNGCTSAGPHFNPSGKTHGGPDDENRHFGDLGNIKAGTVAITDKLVTLTGPNS VIGRTIVVHEGQDDLGKGGNEESLKTGNAGGRLACGVIGI-------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------LLTLRLDREAMYTEFQRTIESVNVIISTYASEDGPMGDFTVEP TKGTVGFGSGLHGWAFTLKMFADMYATKFKVPAAKLMKRLWGDQFFNGQRGFTLYVLTPI YNVFNKCLVETPVLELIEKMGVKLSAEEKELKDKPLLKAVMRKWLPAGDALLQMICVHLP SPVTSQKYRTELLYEGPPDDKVAQAMKECDPKGELMMYISKMVPTSDKGRFYAFGRVFSG TIATGMKARXMGPNFKPVKNIQRTILMMGRYTEPIEDVPCGNICGLVGVDQFLVKTGTIT TFDQAHNMKMMKFXVSPVVRVAVEAKN--------------------------------- ------------------------------------------------------------ -----------------XREDPKERGRYLADTYDWDVNEARKIWSFGPEGTGPNMVIDVT KGVQYLNEIKESVVAGFQWATKEGVLCEENMRGVRFNICDVTLHADAIHRGGGQIIPTTR RVLYASVLTARPKLMEPVYLVEIQAPESVVGNIYGVLHKRRGTVNEATTDRGV-QYTVKA FLPVNESFGFVSHIRQETGGQAFPQCVFDHWDLLVISETRARKKMKEGLPKLDDYLDKLX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------ --------------------------------------------------------KRLI GRSWSEKSVAEDVKFFPFNVIEKNSKPHVRVDVGGDRKTFAPEEISAMVLGKMKEIAEAY LGKKVTHAVVTVPAYFNDAQRQATKDAGSIAGLNVMRIINEPTAAAIAYGLDKKXGEKNI LVFDLGGGTFDVSVLTIDNGVLK------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------DDPELEAIKERVREMEAEAEKLKQMQNEVEKQ-------------- ------------------------------------------------------------ ------------------------------------------------------------ ----VVCNTLAEIEHRGTYESLVSAVREERNRKTGLQDTILKEEEGRRKLKTLQKQLVDV KKEKEVEIQHRNEMIAHLKDQLQEMKAKTNMEGKYIQKCAQVSVAQTLK----------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------GLMTTVHA YTATQKTVVRPSAKDWRVGRTAATNIIPXSTGAAKAVGKVIPELNGKLTGMAFRVPVANV SVVDLTCRLKAGAPYADICAAMKGSLKGVLGYTEDMVVNSDFNGDERSSIFDAKAGISLN DNFVKVVSWYDNEFGYSCRVVDLLAY-----GDDLSTAILRQKVRPNRLMVEEAINEDNS VVSLSQGKMDELQLFRGDTVLLKGKRRKETVCIVLSDDTVASDKIRINRCVRNNLRVRLG DVVSIQACPDVKYGKRVHVLPIDDTVEGLTGNLFEVFLKPYFLVSIPSHSQGRYFVVQGA MRAVEFKLL--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------NPMKDVEVASPPDDSVSSLQFSPGTLTSTFLVAG RWDNNVRCWQVEQNGQTXPKAQQDSTGPVLDVAWSDDGTKVLLPLVTKQQKL-GLASNQA MQIAQHDAPIKTIHWIKAPSYSCVMTGSWDKTLKFWDTRSPNPMMTINLPERVYCADVHY PMAVVGIAGRGIIIYQLENQPREYKTMDSPLKYQHRCISIFLDKKTNGPVGFALGSIEGR VAIQYLSPTNPKDNFTFKCHRGGAQDIFAVNGIAFHPVHGTLATVGSDGRFSFWDKDART KLKTSEQLPMPITCCHFNAAGNIFAYASSYDWSKGHEGFDPHKMKPHVLLRSCYDELKPS NKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMRE EEIETAIKVVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIEINCEDVRLMLW DTAGQEEFDAITKAYYRGAQACVLAFSSTDRDSF-------------------------- ------------------------------------------------------------ ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFIQARFALHPKLKKFSIYRYD PDKPNKKPALQEYEVDLNDCGPMVLDALIKIKNEQDPTLTFRRSCREGICGSCSMNINGA NTLACICKIDEG-SKATKIYPLPHMYVIKDLVPDMNXFYARSGFLGRFLRRKVETRQKXR NEAIFSSPEDRAKLDGLYECILCACCSTSCPSYWWNSDKYLGPAVLMQAYRWMVDSRDDF QHERLEKMRGAYAAYKCHTIMNCTRVCPKGLNPGWAIGEI---------------ENRPG CTVYINNLNEKIKKDELKKSLYAIFSQFGQILDIVALKTLKMRGQAFVIFKDINSATNAL RSMQGFPFYDKPMRIQYSKKDSDVIAKMKGTYVERPKK---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------GMAELLF STIQAADMDTRPVVY-NIVLSGGSTMYPGLPSRLEREIKQLYLERVLRGDTTKLSKFKIR IEDPPRRKHMVFLGGAVLASIMKDKDSFWMTREEYQEKGLGVLEKLGVS----------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------KGTAFGGWKSRESVPKLVEDYLKGIVKVDEFVSHNMPLEKINEAFDLMHSGQSX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX------------LVLLSVVDHFXRSGKWER-ERVVXVLLGSKRGD CLDISNSFAVPFDEDDRDKNVWFLDHDYLEQMSTMFKKVNAKEKIVGWYHTGPKLHQNDV IINELIRRYLPNSVLVIIDAKPKDLGLPTEAYIAVEEVHDDGTPTTKTFEHVPSEIGAEE AEEVGVELLLRDIKDTTVGXLSQRITNQLMGLKGLLSQLQDIRNYIEKVNQGQLPINHQI VYMLQDIFNLLPDVTLQDFVKSMYVKTNDQMLVLYLSSMIRSQSQLHNLINNKLQNRDAE KNGGARTAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXX--IPTRRVLLNDPSQLPHDYSTTPGGTLFSTTPGGTRIVYERHFLMQCRNSPLA KSPPPNLPKIPGVT--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------- ---------------------------------------------------------MQD CLTGCMFVMIPAGVPRKPGMSRDDLFNTNASIVRDIADAAAQYCPQAMMCIITNPVNSTV PIASEVFKKRGVYDPNRIFGVTTLDIVRANAFIAEAKGLDPTKVKVPVIGGHSGVTIIPV ISQATPGVSFKQEEREKITKRIQN-------AKAGGGSATLSMAYAGAQFAFSLLQAMNG KEGVVECAYVKSDETDAKYFSTPLQLGRNGVEKNHGVGNLIEFESQLLDQAMDELKANIK KGEDLLI--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------ -----------------------------------------KIHFIAPNIYCCGAGTAAD TEMTTQMISSNLELHRLNTGRVPRVCTANRMLKQMLWRYQGYISAALVLGGVDPTGPHLY SVYPHGSTDKLPYVTMGSGSLAAMSVFESRYKPDMEKEEGMKLVRDAIAAGIFNDLGSGS NVDLCIITKKVDYI--------------------------------------XXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------- ----------------------------------------KLNIWDVGGQKSLRSYWRNY FESTDGLIWVVDSADRRRLSDCKEELHQLLVEERLAGATLLVFANKQDLPGALPAEEIK- ALELDLIKTHHWLIQGCSAVTGENXLQGMDWIIQDISSRIFTMDXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVSPGS RCSLCLESRKHSTATPCGHLFCWDCILEWCESKLE---CPLCREKLEPSRLVCL------ ------------------------------------------------------------ --------------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXEEENATSKLFTDALNSPEIDGWDLRGIGNDF AGGELIPDADICIAYINACRRVNDYALGVRFLE----------------------PALEE VGMDIPEELGYDKPELAVKDV---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXYRDREKPTAVRDSNITAAKAV ADAIRTSLGPRGMDKMIQSANGDVTITNDGATILKQMQVLHPAAKMLVELSKAQDVEAGD GTTSVVVIAGSFLDASAKLLAKGIHPTTISEAF--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXM LTFCPVCANVLVVEEGQKCFRFACNTCPYVYNIQTK-DYKXIPRLKEVDDVLGGAAAWEN VDSTEEACPKCAHPRAFFMQIQTRSADEPMTTFYKCCDMKCGHQWR-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------YHHESCGQCTPCREGVGWMAKILHRFVKGNA RPDEIDMLYEISKQIEGHTICALGDGAAWPAQGLVRHFRPQLEERMAQYHA--XXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX X----------------------------------------------------------- -------------------EKGPRRTMNTIRKTLSGGRYRKELTMDAMRRASAILKSQQP RVTKQTRDEPYYCSQQINIPPELPDILKQFTKAAIRTQPKDVLAWAAAYFRAMSKGETPP VKERLEMPVATQKTDTGLTPGLLRILNKQLGPRKTVPLSQIEEKWKDLSLPKEQFDELVR IGSFGGDTEWLKFFSLAASTLGENITNAMKTICEILTADPEGGPCRIPFQLFKDLYKYLA QIDGEISKEHIDEVISHLQYDVDKQDGFVQPRNFLSPDCPKLSXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- ------------------------------LVQHMVDCIKEVNTVVQLPATTTRILLSHF RWDKEKLMERYYDGDQDQLFSEAHVVSPGRKMS---------QQLRMMTGLECGHRFCTA CWTEYLTTKIIDEGMGQTISCAAHGCDILVDDATVMSLVKDSKVRLKYQHLITNSFVECN RQLRWCPAPDCGRAVKVNYPDARPVTCQCGHTFCFSCGETWHDPVKCKWLRRWIKKCDDD XETSNWIAANTTE----------------------------------------------F DEDEAKKARDSQEKSRSALQRYXFYCNRYMNHMQSLKFEHKLYSMVRQKMEEMQQHNMSW IEVQFLKKAVDILCLCRQTLMFTYVFAFYLXKNNQSIIFEDNQKDLENATEQLSEYLERD ITSDIIVDVKQKVAGXNQICESRCKVLLDHVHEGYEKE------XXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------DLAGRLSRGGKGGMFGMGGLIA AGALAYGLYESFYTVEGGHRSIIFSRIGGVQNDIFTEGLHFRVPWFQYPIIYDIRAKPRR LSSPTGSKDLQTVNITLRVLARPDPLRLPDIYRTLGMDYDERVLPSIVNEVLKSVVAKFN ASQLITQRAQVSMLIRKNLMDRAIDFNIILDDVAITDLSFGRDYTSAVESKQVAQQEAQR AKYVVERAEQER------------------------------------------------ -----------------------SYTGSSSDDDDINPREKEQQSSQGFKDFCVRIEQHAF GRREIEIAEQEMPGLVALRKRAQDDKPLHGAKIIGCTHITAQTAVLVETLTALGAQVRWS ACNIYSTQNEVAAALSEAGYS--------------------------------DSGDATH LMLKKYPHLFNQIKGIVEESVTGVHRLYQLSKSGKLTVPAMNVNDSVTKTKFDNLYLCRE SIIDALKRTTDVMFGGKQVLICGYGEVGKGCAAALRGLG--------------------- --------------------------RSTLDRLKNGCIVCNMGHXNTEIDVGSLRTPELT WEKVRSQVDHIIWADGKRIXLLAEGRLVNLSCSSVPSFVVSITAXTQALALIELYNAPPG RYKQDVYLLPKXMDEYVASLHLPTFDAHLTELSDEQAQYLGLNKAGPFKPNYYRYXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXYIAGCLGGIAGL-VRHPFDTTKVQMQTQLAHYKGTWDAIKNIY-HHGGRGF FRGLSFPLINSVFFGVYG------------------------------------------ ------------------------------------------------------------ -------------------------------------------------XXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------------------- ------------------KEKKRYEKQLNQIDGTLSTIEFQREALENASTNTEVLKVMGT AAKALKSAHNDLDVDKVHDLMDEVAEQQDIANEISEAISNPVGFGTDVDEDELMAELEEL EQEDLDAQLLEVG---------------------XXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXX------------------------------------ ------------------------------------------------------------ ----------------------LIRQDKSRLW--LLPGIIKPGECKFGIMPGHIHKPGKI GIVSRSGTLTYEAVHQTTMAGMGQSLCIGIGGDPFNGTNFXDCLEIFLKDPETEGIILIG EIGGDAEEKAASYLMEHNGPHSKPVVSFIAGLTAPPGRRMGHAGAIISGGKGGAQEKIAA LNNAGVEVTKSPAQMGSTLRKAMEAAGKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFSRYVEIGRVAFVA FGPDQGKLVAISDVIDQNRALVDGPCTGVARKCMNLKQLHLTKYVLYGHGARTGTIRKAW EKAKISEQWAESTWAKKLARREQRAQLTDFDRFKLMKAKQARNRLIAIEYGKLKKAAKXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----------------LPPPSEDYDEQX GIKKVTEYKINEDGKKVKVVKI-SVETRRVFRPFAKGRLWRKFGLAANDPXWPNPANTVE EVYIXFVHNKEVDSERSLA-IKLLVVFVKVDHLDHKMPYKDTLGPIQETLKVGGKYVPPS LREG-------------------------------------------------------- -------------------------------------XXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXX------------------------------------------------ -------ESSTRRRYSDFEWLRNELERDSKIVVPPLPGKALKRQLPFRGDDGIFEDEFIE ERRKGLEQFVNKVAGHPLAQNERCLHMFLQEPMIDKNYVPGKVRTT-------------- ----------GSLFIHKKLGYRGVXLYPCQAKIYDRDISVT------PAEEIYYQVLVDL EDTSMEGAGNEECIFMAQKGELKPQILNGFGFVAHEDMLPYTSTSDWPVEHAEFENFFT- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXX---RYKCVVLRAMFEETRNIDQENAVNLLRKWQLYLELDAHPER-GFPAEPGG-- -------------------------------------------------XXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------LGIGVAAVGSVINSALY NVDGGHRAIMFDRFRGVQQNVIGEGTQFMIPIVQKPYIFDCRSRARNRPXVTGSKDLQNC NITLRILFRPVQEELPKNFINLGLDYDERVLPSITQEVLKAVVAQFDASELITQRELVSQ KVSEELMDRAAKFGIICDDIALTHLTFGKEFSEAVELKAVAQQKKEK------------- ------------------------------------------------------------ ---MKTLVSGQFVKIPDNVEVKVHSCKVMVKGPRGTLRRDFRHLAVDMKLVSKSLLRIDK YFGTRKELAAVTTVCSHILNMIKGVTKGFQYKMRSVYAHFPINISILNGGKNVEIRNFLG EKYIRAVAMQPGVICTASSAQKDEFILEGNDIELVSRSAALIQQSTKVKNKDIRKFLDGI YVSEKGTVVKD------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------AYIQLQFNKRAETKDIYCHFTCATDTNNVQFVFDAVTDVIIKNNLKDCG LFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- ---------PCKYMSNGCAVNLLHTEKTEHEETCEFRPYCCPCPGASCKWQGSLDQVMPH LMQHHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGYNFMLVLEKQEKMDGHQQFYA IVQLIGTRKQAESFIYKLELNGHRRRLTWEATPRSIHDGVQSAISSSDCLVFDTNIARLF AEGGNLGINVTISMCXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXEFFKAFLAQAKAEFSDKWEKPSQNTAGLDDFERIKTL GTGSFGRVMLVQHKQSKQ------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -MLADTILIVIISICTALMGEGLTWLLVYRTEXIQKIKSRVEKASKKLEKTKEYSN-EAD RSQKKKKE---------------------------------------------------- ----------------------------------------------------------CV ENFQTWSEMDQVDFVEHLLSLMCHYQHGQVNTFLKPMLQRDFISALPAKGLDHIAETILS YLDFKSLCSAELXCKEWYRVIADGMLWKKLIE---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXANGETSADRNVEIWKIKKLIKSLEAARGNGTSMISSLF HPNE-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------XXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXX---------------------------------------- --------------------------------FFVGEQIGRRSIIGYNIPG-------XX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------- ----------------LHPPHYRWDFKGYFAAYDXPSVRRGYQVYKQVCRVVTPWNLMXI AILWTCVNSEREAKREAEEAMVWDGPNDAGQMFQRPGKLSDXLPKPYDNVEAAKAANNGA YPPDLGHVVLAREEAESYIFALLTGYCDPPAGYELADGMAYNPYFAGGAISMAQALYNEI IEYEDGTPATQSQLAKDVVTFLSWASDPDLEQRKXFGIKAGVVLMTPVAYYYKRFKFHTL FTQQIFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------ ------------------------------------------------------------ ---------------------------------------------------XRHGQGVYT YAETGTKYTGTWKEGKREGAGDLIHANHKYVGQWKEDRPEGKGKYVFDIGCEQHGEYIXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXSIDALSFHLPINQKKCLKEEIHKNVLVTGIYDLTEAPGQRTKL VVVDSRGHILYQKDDASKGKFAFTTEDYDMFEVCFETKLPMGTHAPDREVIIDIKTGVEA KNYEALAKAEKLKPLEVELRKLEDLSEAIVNDFAYMRAREEEMRDTNESTHSRVLYFSIF SMCCLLGLASWQVLYLRRYFKAKKLIEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------AFMNPRLLDDLSF HPCVRFKRWEAERVISFVPPDGSFRLMSYHIGTQNLVAIPV-TDTNISFREGSGGRFDVS VGPKQTMGKTVENVSLEVPFPKSVLNVTLTP-KGKYTFDPVNKIMVWEIGRIDPKNCPNI KRILSVTSGAPIPEXYPTISVNSLSIQMAISXMKVNRLXMYG------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------DDVEAQLHKEVEVIDGIKKQLQQKCSEAFEQLCLLQEARQQIIMDLQ DKNIALGIDVDQYNLTERSPLISFKPDPTRVPKGSVTPQNWEDFSRYNKERAEAEMNAST RLREAIHHTLQQTANDLEAQRLATEYAYRKRIHETERAKGELEWQKQNTEEEIAQLEEDI RGIERAIRDKINPMKLAQTRLENRTYRPNVELCRDHVQYGLTDEVKQLEATKKGLEEKLR QAKHALDGLEQNLHRINEDL-----------------------------XXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXX---------------------------------------QAAACIPLLDLA QRQHGWCPISVMHYVADMLSMPRMRVYEVATFYTMFNREPVGKHFIQICTTTPCMLGGVG SDVILEAIKTKLGIEVGETTKDNMFTLAEVECLGACVNAPMVQINDDYYEDLTVDDMNSI LDDLIAGKKPKAGPRSGQNHRFACEPKGGLTSLKGTPTGPGFGVRSDLXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----FLVHEGPKPGVSYPLHP EC-SMPFEYCENGPSFDKCKKWLQDNLPEEFERLHVKRQKRGGRGVPKSRKKAAPQSVCL SRASRGKKXYVTVVTGLATYEIDLKDASKCFGSKFACGSSVTGDDXIVIQGDVKDELFDF ITEKWPQISEDNIDDLGDLKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSLETVPKDLRNLRECLLCSLVKTFEQFERD GCDNCEEYLHMKNNREXVYDCTSSSFDGLIAEMGNEDSWVXKWQRINRFEKG-------- ------------------------PQFYQYLSKEQEKELARIANAIVAPGKGILAADEST GTIGKRFSPINVENTEENRRLYRQLLFTAAAEHLSGVIMFHETLYHKTDDGTPFVKVLKD SGIIPGIKVDKGVVPLAGTDDECTTQGLDGLAERCAQYKKDGADFAKWRCVLKIKPQCPS YQAMLENANVLARYASICQQNGLVPIVEPEVLPDGDHDLETAQRVTEQVLAFTYKALSDH HVFLEGTLLKPNMVTAGFSCSKKYTAEDIARATVTTLARTVPAAVPGITFLSGGQSEEEA SVNLDAINRRPWALTFSYGRALQASVLQAWGGKKENVPAAQQELVKRATANGNAALGKYS GGEQGAAGKSLFVAGHAYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------LLP LNMIGVEEDKEESLEDSLLSCWSGLKSTFSYAGFRNATKEIHKPRIALLNIELELKAEKE NAEVRVDSVEEYQAVVDAEWNILYGKLGKIHKSGAKVVLSKLPIGDVATQYFADRDLFCA GRVPDEDLKRTLKACGGSIQTTVANLALGTCELFEEQQIGGERFNIFTGCPQAKTCTLIL RGGAEQFIEETERSLHDAIMIVRRAIKNDAVVAGGGAIEMELSKYLRDHSRTIAGKEQLL IGAMAKAXKLVPRQLCDNAGFDATNILNKLRQKHAGTWYGVDITAEDIADNLKACVWEPA IXKINALTAASEAACLILSVDETIKNPKAGEG-GPAGRGRGRPMKRNNMVPNGHFHKDWQ TRVKTWFNQPARKKRRHDRRVKKARLIAPRPVAGPLRPVIRCPTFKYNTKVRLGRGFTLD ELKAAGLNKKFARTIGISVDYRRRNKSVESLQQNVQRLKEYRSKLVLFPKKLSAPKKDDS GPEELKMATQLSGEVMPIIAVPKKEKARAISEEERKYSAYTALRQARANKRLFGIREKRA KEKMPNIKIFSGTSHADMAQKIAERLGIELGKVTTKXFSNQETCVEVGESVRGEDVYIVQ SGCGEINDMLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSPISANYVANMLSVS GAD--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------LFCRFYAHKFPEVEDVVMVNVRSIAEMGAYVHLLEXNNIEG MILLSELSRRRIRSIQQIXKIGRNECVVVIRVDKDKGYNXFSKRRVSXEEVMRCEEKFAK AKTVNSILRHVGELLXYESDEQLEEVSNKKNRHLMTNMEKQVASYEAFKHAVTNPEILDE CDIDDHTRXVLAANIKRRLTPQAVKIRADLDVRCYGYEGIDAVKSALNAGLNLSTEDMPI KINLIAPPTYVMTTTTLERVEGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------- ------------------------------------------------------------ ---------------------------------------------CVGEKLDEREAGLTE EVVFRQTKASDWDKVVIAYEPVWAIGTGKTATPDQAQEVHXQTTQWLSENVSPAVASSVR IQYGGSVNAKNCRXLAEKXDVDGFLVGGASLKPEFVTIVNAREREGLLDPAWEXQQRKTF TAWCNSHLRKVGTQIENIEEDFXNGLKLMLLLEVISGEQLXKPDRGKMRFHK-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------NKLSIDALDLGGKRVLIRVD FNVPLKGKEITNNQRIVEALPTIKYALEKGAKSVVLMSHLGRPDGNRNDKFSLAPVAEEL KKLLGRDVTFLSDCVGTEVEAACASPAQGSVILLENLRFHVEEEGKGVDAEGKKVKASVD AVEQFRASLSKLGDVYVNDAFGTAHRAHSSMVGVQHGQRAAG------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXX------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------PTEVLFLMNMVVPEELEDEEEYEEILE DVREECGKYGIVRSMEIPRPIKGVDVPGCGKIFGEFNSVIDCQKAQQALTGRKFANRVVV TSYYDPDQYHRREFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------- ---------------------------------------GPIVMLEXTIDDAEDTSTKKQ LLKQLAQVEEDLGFLRDQTTTIEV-XARVYNWDVKRRQALKSMADEALARAGLHFDELNK IRVLEPEVSQDTTELKEXCKDFVDKMGEFQKIVGSFIDMVDKVSKEVEKEKMKAIGSRNL LKSIAKQREAQQQQLQALLAEKKMQSERLRVQYEALQKEEAEQNEFIEQFILQKXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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SRAQAQIAARQDVSRVVIWGNHSSTQYPDVRHAVIVQDAVKDDSWLKNEFIKTVQTRGAA VIKARKLSSAMSAANAICDHMRDWWHGTPEGKWVSMGVSSSGYGIEPELIYSFPVTIGRN WKIVEGLPIDDFSRDKMDKTMKELQEERSTALE--XXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXTSTTNALKEEDCPVCIKFLTKFMNTLELKHEKFRKFC KSAKNKDERLCYYIGALETSATGILGEMSKPMSWGVPADKL------------------- ----------------------------------------------------XXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVVSKAARLSSLQQRR EKGDLILTFASPGDVSVKQVDVPTLAGSVGILPDHVPWIGCLKPGLLSVFEESGTKVQYF VSSGTATVNPDSSLQILAEEAVPVDRLD-------------------------------- -------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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------------------------------------------------------------ ------------------------------------------------------------ -----------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-- ------------------------------------------------RVTCLDWAPESD RIVSCGVDRNAYVWPTLVILRINRAATCVRWSPQENKFAVGSGARVISVCYFEKENDWWV SKHIKKPIRSTVTSLDWHPNNILLAAGSTDFKARVFSGWIKECEAKPQETPWGKKMPLGN LMVEFSDAGGWVHXVGFSPSGDKLAWVGHDSSVSVVSVNVKTTFLPFLSLIWATENSIVV AGHDCCPVLYSTDDQKLAFVSKLDIGTLSAMKRFQTLDKKATDLKTKHQNSITQLSVYSG SREQVTKFASSGVDGQIVVWDFK------------------------------------- ------------------------------------------------------------ ---------------------------------DNRVHCCLYLXNPSGHGLKPLDVEFMK RLHDKVNIIPMIAKADTMTPDECREFKKTILNEIAQHKIKIYEFDDEEENKLQKKLKDRV PFAVVGSNTLVSVGGKTVRARQYPWGIVEVENLEHNDFLALRNMLVRTHLHDLKDVTNNV HYENYRYNKLASVA---------------------------------------------- ---------------------------------------------RTTIFSPEGRLYQVE YAMEAIGHAGTCLGILAKDGVVLAAERRNINKLLDEVSFSEKIYKLHEDIACSVAGITSD ANVLTNELRLIAQRFYLQYQEPIPCEQLVSHLCDIKQAYTQYGGKRPFGVSLLYMGWDKH YGFQLYQSDPSGNYGGWKATCIGNNSAAAVSLLKQEYKEDEMDLKAALALTIKVLNKTLD MTKLTAEKFELSTLTRENGKTRIRILRQSEVEGLIKAHEKKKKRKEKSEAKXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXDGKPARLLASKTILNQYLVEGKDLTVEYNIYNVGESTAVDVQLVDMGFPQSDFETVR GSLRVKWERIAPGTNVSHAAILSPLK------------------EVQLTYTTAPGEEGIV SRKDYDRKFSPHVIDWVTFAIMTLPSIGFPFMLWYSSKSKYDT-KPKKNGGGSHKDLTEK YRAIFSLVENLKLFTESMLNENVSLVISRQILTEFGNHLTQLDEEVAKXCVSFFLEKIQP RVXSFEEQVAALRQHLAGIYEREQRWREAASVLVGIPMETGQKQYTTDYKLQTYLKIAQL YLEDDDPVNAEAYINRASLLQADTQNEELQVYYKACYARVLDYRRKFIEAAQRYNELSYR S----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXX------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------SVSAQSKLVSAMCKEAVNASFE MSLREGLHFEKRTFHATFATHDRMEGMTAFIEKRPADFKD >Lottia_gigantea MTDRKAVIKNADMSEDMQADSIECATQALEKFNIEKDIAAYIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAILLYKSGMLNQLRSFQTSAMRRDIDQAAKYIGAGAATA GAAGSGAGIGSVFGSLVLAFARNPSLKQQLFSYAILGFALSEAMGLFCIMMAFLFLFALM SYAKETSKAPQVKNHRIRITLTSRNVKSLEKVCSDLISGAKDKQLKVRGPVRMPTRILRI TTRKTPCGEGSKTWDRFQMRIHKRIIDLHSPSEIVKQITSISIEPGVAVEVTIADMDQVM QVVEPAKQFVKDSIRLVNRCTKPDRKEFQKIAMATAIGFCIMGFIGFFVKLIHIPINNII V------KKRKFVADGVFKAELNEFLTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVL GEKGRRIRELTSVVQKRFNFLENTVELYAEKVATRGLCAIAQCESLRYKLIGGLAVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFIDGLMIHSGDPLLEYVDTAIRHVLLRQ G------------------------------------------------------GRGGS AGGKFRICACLPVGAIINCADNSGAKNLYIMAVAGVGGRLNRLPAAGCGDMVVATVKKGK PELRKKVMPAVIVRQRKPFLRKDGVFIYFEDNAGVIVNPKGEMKGSAITGPVAKECADLW PRIASNASSIRKGKSSAISLGPQVEEGEDVFGIAHIYASFNDTFVHVTDISGKETICCVT GGMKVKADRDEASPYAAMLAAQDVAEKCKNLKISALHIRLRATGGNKTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDCNRRKGGRRGRRLMGKPSGLHTARKLRGHRRVQKWHDKD YKKAHFGTRWKANPFQGSSHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP NDGCLNFIEENDEVLVAGFGRSGHAVGDIPGVRFKIVKVANVSLWALFRGKKERPRS--- ATIRTRKYLTNRLLCRKQMVVDIIHPGKATVPKTEVREKLARMFKTTPDVITCFGFKTKF GGGKTSGFALIYDNMNVAKKFEPKYRLVRQGGRKQRKERKNRQKKVRGTAKAKVGAMGRI PRVQSKTYATPRRPFEKERLDQELKIIGEYGLRNKREVWRVKYTLGKIRKAARELLTREE KDPKRLFEGNALLRRLIRIGVLDESKMKLDYVLGLRLEDFLERRLQTQVFKLGLAKSIHH ARVLIRQRHIRVRKQVVNIPSYIVRLDSQKHIDFSLRSPYGGGRPGRVKRQNMKRAEAGG GGMGSAIAKLFGQLLGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVIDSNDRERVGEAREELNRMLSEDELRD AVLLIFANKQDLPNAMNAAEITDKLGLHSLRGRTWYIQATCATSGDGLYEGLDWLSGQLK ---MPLATDLLHPSLEDEKKKSKLRRLVQAPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRRKQHMVMISVLAMALNRITAAERRGKRQVILRPSSKV IIRFLTVMMKHGYIGEFEIIDDHRNCKIVVNLTGRLNKCGVISPRFDVSIRQLEKWTNQL LPSRQFGYLVLTTSGGIMDHEEARKKHLGGKILGFFFMGRMHNFGKGISKSALPYRRTVP TWLKLSAEDVQEQIYKLAKKGLTPSQIGVILRDSHGVAQVRYVTGNKILRILKSKGLAPD IPEDLYHLIKRAVVIRKHLEKSRKDKNAKFRMILIESRIHRLSRYYKTKRVLPPNWKYES ATASALVA-----EIKLFGKWTSDDVQVSDISLTDYIAVKEKFAKYMPHSAGRWQLRRFR KAQCPIVERTVCSLMMHGRNNGKKLMAVRILKHTLEIIHLLTGENPLQVLVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVDQAIWLLCTGAREASFRNIKSIAECLADELINAAK GSSNSYAIKKKDELERVAKSNR--EQMTLRGTLTGHSGWVTQIATNPGFPDTLLSASRDK TLILWKLTKDTNYGIAHKSLEGHSHFVSDVVLSSDGQFALSSSWDSELRLWDLMEAKSSR RFVGHEKDVLSVAFSADNRQIVSASRDKTIKLWNTLGVCKYTVEDCHKDWVSCVRFSPNS NNPIIVSCGWDRVVKVWNLTNCKLKTNHKGHKQYLNVVTVSPDGSLCASGGRDSQAMLWD LNEGKHLYTLDGGDCINTMTFSPNRYWLCAATGPSIKIWDLEGKIIVDELKPELISGQGG IPQCLSLAWSPEGQTLFAGYSDNVIRVWQVSLTARMREYKIVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKQVEVDGCQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTWNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERMVGKLARQFNCGFLETSAKAK VNVSEIFCDLVRLINQKNPEK--DEKI-GSEHINLKVTGQDGSVVHFKIKKNTPLRKLMS AYCNRAGITAGAVRFRFDGNPMNDDDTPISLDMEDGDSIDVFQSQTGGMATLPMNPKPFL NGLTGKPIMVKLKWGMEYKGYLVSVDGYMNLQLANTEEYIDGMLAGNLGEILIRCNNVLY IRGVEEEDEEGEFKDMSDEEGDNVPAAPAASGPMDLYTALQEVLKTSLIHDGLARGLHEC AKALDKRQAHMCILANNCDEPAYVRLVEALCAEHGINLLKVDDNKKLGEWAGLCRIDKEG KARNVIGCSCVVIKDYGKESQALDIINEYFKSKKMAGIRKKLVIVGDGACGKTCLLIVFS KDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSI DSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDENTKRELMKLKQEPVRPDEGRA MAEKINAYSYLECSAKTKEGVREVFETATKAALAVRKKKKGGMDDFQSAEETAFVIDEVT TIIKEAVEGAIGGNTYQHNKVNQWTSNVVEQCLNQLTKLGKPFKYIVTCVIMQKNGAGLH TASSCYWDNTTDGSCTIRWENKTMYCIVSVFGLAIMYNFRSKIRKPNGERPSDIEYSLIQ ALFELETNSDLKLQLRELHIVSAREVEIAGKKAIVIFVPYILLRNFQKIQTRLVRELEKK YSGKHVVFVAQRKILAQPKRNCKQKNRGKRSRLRTLTKVHEDLLDDICYPAEIVGKRIRI KLDGSRLIKVHLDKTQQTNIEHKVDTFSAVYKTLTGKDVKFEFPENMLTRGGFRGGFG-- GRGRGRGRGRAKE-EKDWVPATKLGRLVKDGKIKSLEEIYLFSLPIKEFEIIDLFLQGTL KDEVLKILPVQKQTKAGQRTRFKAIVAVGDNSGHVGLGVKCSKEVATAIRGAIIAAKLSI VPIRRGYWGNKIGKPHTVPSKLTGRCGSVLVRLIPAPRGTGIVSAPVPRKLLTMAGIDDC YTSCKGATSTIGNFAKATFFAIIQTYKFLSPDMWKDSVLTKEPFQEFSDHLHKMSGGLDV LALKEEDVTKFLVCGTHLGATNCNHQMKQYVFKRKPDGIHIINLRKTWEKLLLAARIIAA VENPADISVLSARPYGQRAILKFATYIGATPIAGRFVPGTFTNQIQAAYREPRLIVATDP RTDHQPITEASYINAPIISLCNTDSPLRHIDIAIPCNNKGVHSIGLVWWLLTREVLRLRG TISREHPWEIMVDLFFYRDPEEIEKETEVTDWASESIANPLPS-NTDWSGSGEKEWTGTA PANDWGGMKFNKLVSASRRKNRKRHFTAPSNIRRKIMSAPVSKELRTKHNVRSVPIRKDD EVQVVRGHYKGQQVGKVTQVYRKKYVIYVERIQREKANGATVHVGIHPSKVVVVKLKMDK DRKKILERKAASRKGGKHTEESI---SSTSVGTVARQRKPGGTAGSSAGMWKFYTEDSPG IKVGPVPVLVMSLFFIASVFMLHIWGKYTR-NKRDKKKSVANEVITREVTIHIHKYIHSV SCKRKAPRAIKEIRKFALKMMKTPDVRIDTRLNKYIWSKGVRSVPFRIRVRLARKRNEDE DSIHRLYTLVSYVPCTDFSGKESITVESTTKGEFVVGGKYRLVRKIGSGSFGDIYLAINN TNGEEVAVKLEATKARHPQLLYESKLYKILQGGVGIPYIRFYGEKEYNVLVLDLLGPSLE DLFNFCSRRFTMKTVLMLADQMIGRIEYVHNKNFIHRDIKPDNFLMGIGRHCNKVFLIDF GLAKKYRDSRSRTHIVYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRGS LPWQGLKANTKKQKYEKISERKMSCPVEVLCKGFPAEFCMYLNYCRGLRFEEAPDYMYLR QLFRILFRTLNYQYDYTFDWTMLKQKAAAQMNPEKLKLRIGGKGSARRKRKVQHRTTITD DKKLQSSLKRLGVNSIPGIEEVNMIKEDGQVIHFNNPKVQASLAANTFAVTGHAEMKQIA DMLPGILNQLGAESLSSLKKLASTSGDVD-DDDDVPDLIENFDEASKGEMVRYSSEPDNP SKCAKARGAYLRTSFKNMRETANTIKGMPLARATRYLKNVMEKKEIVPFNRFNGAVSNHA QAKNFKSMQGRWPKKSADFLLQLLKNAESNAEFKGLDTDHLAITHMQINMAPKIRRRLYR AHGRINPFMSTPCHIELILTEKEEMVPKPVKRKVSKKKLARQKAKMRDKKTGPKPELTEE QKQEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKDGHGTIDFND FLTIMTQKMSEKDAKEEILKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQEADRD GDGEINQEEFLRIMKKTSLYMGISRDKWHKRLKSGGRRPQPRKKRKHEMGRPPAQTKMGP KRIHIVRTRGGNSKHRALRLENCNVNWSTQGITRKTRIVDVVYNASSNELVRTKTLVKSA VIQVDANPFRQWFENHFGLPVNLKKGGKKDDDKKKEKKKKDKPVAKKLQNRKKLFKVEPS LQEQFRNGRLIVKISSRPGNCGRCDGYVVEGKELEFYLKKVKSKK--MALVIPEKFQHIL RIQNTNIEGKRKIMYAMTAVKGIGRRFANIMCKKANIDLRLRAGELSEEDVERLVTVMNN PRQYKIPDWFLNRQKDIKDGKFSQILSNGLDNKLREDLERLKKIRAHRGLRHYWGLRVRG QRTKTTGRRGRTVGVAKKK----DSDGDDSPPELEELAQAAGLNEETVSRQKQSRSEKKA RKAMAKLGLKAVGGVTRVTIRKSKNILFVINKPDVFKSPASDTYIVFGEAKIEDLNQAAQ ISAAEKFKADEEIDDTGVEAKDIELVMSQANVSRSKAIKALKNNSNDIVNAIMMPSVRTK TIKKASRVIIEKYYMKLTTDFHVNKRICDEIAIIPSKKLRNRIAGYCTDLMKRIAKGPVR GISIKLQEEERERRDNYVPDVSAIDEIDPDTKEMLKAMDFANIPNLQVVQPIAVAMKWQY KEEHPFEKRRAEGEKIRKKYPDRVPVIVEKAPKARVGDLDKKKYLVPSDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYGMRELKIAKL CLNICVGESGDRLTRAGKVLEALTGQPPVFAKARYTIRAFGIRRNEKIAVYATVRGPKAE EILERGLKVIEYELKTRNFSNSGSFGFGIQEHIDLGIKYDPSIGIYGMHFYIVLGRAGYN VSKRRRCKNRIGIKHRITKDEAMKWFQQKYDGIILPGKMGIKFLEFVKPFCAVLPEVSKP DRKIQFREKILWTAITLFIFLVCCQIPLFGIMSSDSADPFYWIRVILASNRGTLMELGIS PIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMVITVGQAIVYVMTGMYGDPAD IGAGVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFITTNICETIVWKAFSPATVN TGRGTEFEGAIIALFHLLATRSDKVRGLREAFYRQNLPNLMNLTATIFVFGIVIYFQGFR VDLPIKSARYRGQFTSYPIKLFYTSNIPIILQSALVSNLYVISQMLATKFGGNFFVNLLG VWADVGGGGPARSYPVSGLCYYMSPPETLSHVAEDPIHAVLYIAFMLGSCAFFSKTWIDV SGSSAKDVAKQLKEQQMVMRGHRDRSMIKELNRYIPTAAAFGGLCIGALSVMADFMGAIG SGTGILLAVTNIYQYFEIFVKEQGEMGGMGMLLFQNQKAFQKQNHVFGYKKLALYLRYVK KVGLGFRTPKEAIEGTYIDKKCPFTGNVNIRGRILMGVVQKMKMQRTIVVRRDYIHYVTK YKRFERRHKNISVHLSPCFRDVKIGDTVTVGECRPLSKTVRFNVLKVMKAAGSRKEFIKF -VNIPKSRKAYCQSPRCHKHTLHKVTQYKAGKASLHAQGKRRYDRKQKGYGGQTKPIFHK KAKTTKKVVLRLECLRCNLRKQVVIKRCKHFELGGDKRKKGQMIMFMPRVIRGQRKGRGS VFKASIRLRKGKPRHRPVDYAERNGYIKGVIKEILHDSGRGAPLARVVFRNPRKFCLQSE LFIAAEGMYTGQYVYCGRKANLQIGNVLPVGCMPEGTIVCSVEQKPGDRGKLAKASGNYA TVVSHNPDTNKSRVKLPSGSKKTVNSNSRAMVGIVAGGGRIDKPMLKAGRAYHKYKAKRN SWPRTRGVAMNPVEHPHGGGNHQHIGKPSTVRREIPAGRKVGLIAARRTGRLRGSRK--- -ARRTKKVGIVGKYGTRYGSSLRKIIKKIEVSQHSKFTCNFCGKDSMKRKAVGIWACKKC HKVVAGGAWTYSTSAAATVRSAVRRLREMKEMGRRPARCYRYCKNKPYPKSRFCRGVPDP KIRIFDLGRKKARVDEFANCVHLVSDEYEQLSSEALEAGRICANKYLVKHVGKDAFHLRV RVHPFHVVRINKMLSCAGADRLQTGMRGAYGKPQGTVARVNIGQPIMSVRSRDNAEGHVI EALRRAKFKYPGRQKIYVSKKWGFTKWSREEYDVKFKAGQLVPDGVTVQYKPDHGPLKAW M---KVLKVMGRTGSQGQCTQVRVEFLDESNRSIIRNVKGPVREGDILTLLESEREARRL RMTKGTSSFGRRHIKTHVMCRRCGRRSFHAQKKLCSSCGYPYPRKRKYNWSEKAKRRRAQ GTGRMKHLNKVFKRFKNGFREGQPKSKKVKMVEDRTTAKELDQWIEQLNECKQLSENQVK ILCEKAKDILSKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDR GYYSVETVSLLVALKVRYKDRITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDQQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHSNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRC GNQAAIMELDDALKYSFLQFDPAPRRGEPHVTRRTPDYFLMGAYKYMQEIYRKKQSDVMR FLLRVRCWQYRQLNPVHRCPRPTRPEKARQLGYKATQGFVIYRVRVRRGSRKKPVRKGIT YGKPKRHCVVRIKFARNLRSVAEEKVGRRCGNLRVLNSYWVCQDSVFKFYEVILVDPFHK SIRRNPRIQWICNPVMKHRELRGLTNAGKNSRGLGKGHKFNKTTGGSRWANWKKHNFEQM HRKRGIALGRLAEERKAWRKDHPFGFVAKPVKNPDGSLNLLNWECKIPGKKGTPWEGGLY SLRMLFKEDYPSTPPKCKFEPPLFHPNVYPSGTVCLSLLDEDKDWRPAVTIRQILLGIQE LLNEPNIKDPAQAEAYTIYCQNRDAYEKRVRAQAIKLLDDSGGRSSKMLQHINFRMRCML HDSRTFIGTFKAFDKHMNIILGDCDEFRKIKPKSNKQREEKRVLGLVLLRGEHLVSMTVE GPPPTEESMARVPLAGGPGGPGMGRAAGRGVG-GPGLQGPVRGVGGPSQQMMAPQPGMMR GPPP-----FQLVLVGDGGVGKTTFVKRHVTGEFEKKYVATLGVEVNSMLFNTNRGHIKF NVWDTAGQEKFGGLRDGYYIQGQCAIIMFDVTSRITYKNVPNWHRDLVRVCENIPIVLCG NKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLAKKLVGDADLTFVEMPA LKPPEVQMDEATLRRYEEELRDAAETALPDDDDN--EGIKQYYVSKIEEQQLIVTEKTQN LRRLEAQRNELNAKVRMLREELQLLQEQGSYVGEVVKPMDKKKVLVKVHPEGKFVVDIDK NIDINSVTPNCRVALRNDSYVLHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEI KEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ KFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSSRLESGSGGDSEVQRTMLELLNQLD GFEPKQNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARQDILKIHSRKMNLTRG INLRKIAEMMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFELAVAKIMLKDSEKNMSI KKQWKLSFFENFALSGAAAVISKTAAAPIERVKLLVQNQDEMIKQGRLSEPYKGVIDCTK KTMANEGFLPFWRGNLANCIRYFPTQALNFAFKDQIKKLFKQKKTDPYMVNFGKNIASGG TAGALSLCFVYSLDYARTRLANDAKSSTKREFNGLIDVYKKTLKTDGIQGLYRGFVISCV GIVVYRGFYFGLFDTLKPILLGDSANILLSFALGYTVTITSGLISYPIDTIRRRMMMTSG QAVKYKGAVDCALQIMKNEGFMSMMKGAGANILRGVAGAGVLSGFDKFQEIYINAKVMGE ISDLDRQIESLRRCEVIKENEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLK ELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQV YGFYDECLRKYGSITVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRAIDRK QEVPHDGPMCDLLWSDPEDMQGWGVSPRGAGYLFGSDVVSQFNASNDIDLICRAHQLVME GFKWHFNDTVLTVWSAPNYCYRCGNVAAILELDEHLQRDFTIFEAAPQEARGKPQPDYFL VRLPPEVNRILYIKNLPYKITAEEMYDIFGKYGAIRQIRVGNTPETKGTAFVIYEDIFDA KNACDHLSGFNVCNRYLVVLYYQANKSFKKVDTDKKKQDLDQMKQKYGLSTPEVKMSIGV PIKVLHEAEGHIVTCETTTGEVYRGKLIEAEDNMNCQMQNITVTYRDGRVAQLENVYIRG SKIRFLILPDMLKNAPMFKKVAAGRGKSAILRAAARGRGRAQPG-----MQNEAGEFVDM YIPRKCSASNQIIHANDYSSIQLAIAEVDETTGRMTGTQKLYAICGKIRFMGEADDCINR LCKKDKII----RGARKHLKRVTAPKSWMLDKLGGVFAPRPTPGPHKLRESLPMCVLLRN RLKYALNYEEVKKICMQRLIRVDGKVRTDKTFPTGFMDVIGIQKTGENFRILYDVKGRFV VHRIKPEEAKYKLCSVKKCQLGQKAIPYLATHDGKTIRYPDPAIKVHDTVMVMGTKDDEY DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDSKTIKAQIWDTA GQERYRAITSAYYRGAVGALLTYDIAKHLTYENVERWLKELRDHADQNIVIMLVGNKSDL RHLRAVPTDEAKAFAEKNSLSFIETSALDSTNVEAAFQNILTEIYKIVSQKQIRDSPDDT NVQTITVAPTENSSGPKKQCCNMSSSYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVR GKNIVVLGVEKKAVAKLQEDRTVRKIALLDEHVALAFAGLTADARILINRARIECQSHRL SVEDPVTLDYITRYIAQLKQKFTQSNGRRPFGLSALLIGFDGTPHLYQTDPSGTYHEWKA NAIGRSAKTVREFLEKNYTEEISSEEETIKLALKALSEVVQTGGKNMEIAVMKRGEPLKM LESDEIEKFIAEIDKEKEEEAEKKKPKGTGGAGDKSDDKDKKKKYEPPVPTRVGKKKKKL KGPDAATKLPQVTPYTRCRLKLLKLERIKDYLLMEEEFIKNQERLKPQEEKHEEERTKVD ELRGSPMSVGNMEEIIDDNHAIVSTSVGSEHYVSILSFVDKDQLEPGCSVLLNHKVHAVV GVLSDDTDPMVNVMKLEKAPQETYADIGGLDSQIQEIKESVELPLTHPEYYEEMGIKPPK GVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPS IVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSHGDVKVIMATNRIETLDPA LIRPGRIDRKIEFPLPDEKTKRRILTIHTSRMTLADDVNIDDYVMSKDDLSGADIKAICT EGGLLALRERRMKITNEDFKKAKENVLYRKNEGTPEGLYLKKRTVSPFQAIDKVDYAVAR IDDLLNWGRKSSIWPMTFGLACCAVEMMHIAAPRYDMDRFGIVFRASPRQADVIIVAGTL TNKMAPALRKIYDQMPEPRWVISMGSCANGGGYYHYSYSVVRGCDRVIPVDIYVPGCPPT AEALLYGLLQLQRKIMRMSVLQSWYRKTEFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYA NNSNYKNDTMIRKEAFVHKSVMEELKRIIEDSEIMQEDDTLWPSPDRVGRQELEVVIGDE HISFTTSKIGSLVDVNQSKDPEGLRTFYYLVQDLKCLVFSLIGLHFKIKPIMVSTKKAKK SSENINARLALVMKSGKYCLGHRQTLKTLRQGKAKLVIIANNTPPLVKSEIEYYAMLAKT GVHHYAGNNIELGTACGKYFRVGALSITDPGDSDIIRNMPT-MTEYKLVVVGAGGVGKSA LTIQLIQNHFVEEYDPTIEDSYRKQVVIDAETCLLDILDTAGQEEYSAMRDQYMRTGEGF LCVFAVNVAKSFEDINTYREQIKRVKDADEVPMVLVGNKVDLQTRNVDPVQAKQVADSYG IPYVETSAKTRQGVDHAFYTLVREIRQYMGDRYNIHTQLEHLQSKYIGTGHADTNKWEWL TNQHRDSASSYLGHFDTLNYFGLVENEAKARVKFSLMEKMLQPCGPPPKRIEDFRIELCS YSGLKIYPGHGKRVVLKDGKTFNFLNSKCCASHFMKRNPREIRWTVLYRRKYKKGNLETI TKKRNRKTVKHERGIAGATLSDILAKRNQPPEVRAAQREQAIRLAAG------KSAPRVG GKR--INVANPATGCQKLFEIEEEKKLRPFFEKRISTDVPGDSLGDEWKGYVFRITGGND KQGFPMKQGVLTTGRVRLLLKKGMSCFRERRAGERKRKSVHGCIVDNSLSVLSLIVIKKG DNEIPGLTDTTIPRRLGPKRASKIRKLFNLSKEDDVRQYVVRRPMPPRTKAPKIQRLITP DTISRRKHMLSLKKRRAEKSREAAADYAKLLAQRIRQAKERR-----------KIKAKDY RGKKKEELDKKLDELKEELQTLRVATVTGGSANKLSKIRTVRKSVGRVLTVMNQTRKENL RKFYVPKQLRRKKTRAIRRSLTDNEKNIKSKKARRKAQNFPMRKFAVKDKPKGPKVTDKV YFDIKIGGEDVGRIVIGLFGKTVPKTVDNFKKLAEGFETYKGSKFHRVIKDFMIQGGDFT RGDGTGGKSIYFADENFKLKHYGSGWLSMANAGKDTNGSQFFLTTKKTSWLDGKHVVFGK VLEGMKVVRKIENTKTSRDKPEKDVEIADSGSIKVDEAFSVEKKDSEERNKKKILKFSVD CTHPVEDGIMDVNNFEKYLHERIKVDGRTNNLKNRIVVSSEIKFSKRYLKYLTKKYLKKN SLRDWLRVVSSDKESYELRYFQINQDDEEEEGDE-------DEKIYGGCEGPDAMYVKLI SSDGHEFIVKRDHALTSGTIKAMLSGPGQFSENETNEINFREIPSHVLEKVCMYFTYKVR YTNSSTEIPEFPILPEIALELLMAANFLDC-KTYRLEEISKHKTAKSTWLVIHDEVYDVT KFLEEHPGGEEVLLEQAGGEATESFEDVGHSTDARELMKEYLIGKVHEVSKSSWTGWLLP LGIAITAALVYRFLMSYMLQHLHNGWQVDQAILSEEDRAVIIRFGHDWDPACMVMDETLY RCAEKMKNFAVTYLVDISKVPDFNKMYELYDPCTTMFFYRNKHIMIDLGTGNNNKINWPM EDSQEFIDIVETVYRGARKGRGLVVSPKDYSTKYRYKKLQRQLEFLEVQEEYIKDEQKNL KKEYLHAQEEVKRIQSVPLVIGQFLEAVDQNNGIVGSTTGSNYYVRILSTIDRELLKPSA SVALHKHSNALVDVLPPEADSSITMLSADEKPDIQYADIGGMDIQKQEVREAVELPLTHF ELYKQIGIDPPRGVLMFGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVR DVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTVNVKVI MATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITAKMNLSEEVDLEDYVARPD KISGADINAICQEAGMQAVRENRYVVLAKDFEKGYKNNIKKDETEHEFYK---------I ESRVLEVIKKYDKINAEKLTLDSHFMNDLGLDSLDQIEVIMAMEDEFGFEIPDADSERLM RPKDIIQYVADRDDI-RRV--LEDDLKNVEFETSEEVDVTPTFDNMGLREELLRGIYAYG FEKPSAIQQRAVKPITKGRDVIAQAQSGTGKTATFSISILQTVETQLRETQALCLAPTRE LAVQIQKVILALGDYMNIQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIKRRNLR TRSIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVLLISATLPHEILEMTSKFMTDPI RILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKM REANFTVSSMHGDMLQKEREAIMKEFRSGESRVLITTDVWARGIDVQQVSLVINYDLPNN RELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI------ --------------------------------------------------------KFSI GMDCSVTPLRHGGLSLVQTTDFFYPLVDDPYMMGKITCANVLSDLYAMGVTDCDNMLMLL GVSNKLSVKERDVIVPMLMRGFKDCAAEGGSSVTGGQTVLNPWMTIGGVATTVCQPNEFI MPDNAVMGDVLVLTKPLGTQVAVNAYTWLDQPERWNRIKLVVSEDDVRKAYQRAMFSMAR LNRTASRLMHKYNGHGATDVTGFGLLGHANNLAKIQKNEVGFVIHNLPVIAKMASISKAC GNMFGLLQGQSAETSGGLLICLPREQAAAFCKDIEKQEGYQSWIIGIVEKGNRTARIIDK PRVIEVPAKDRDVFVSLISSINCYFIQIDAHAEECFFDKVTSGTKMSLSFEVAEGGFLDI DVKMYGPDGKVIHSVDRESSGKYTFAAYMDGIYKYCFGNKMSTMTPKIVMFSMDIGEKPK ANHNKLSEMIVELSTALTGVKHEQEYMELRERTHRAINNNTNSRVVLWSFFEALVLVAMS LGQVYYLKRFFEVRRVVMAATLKPYLNAVRNTVTAAMCVQNFDSQVVERHNKPEVETKSS KELLLQPVIISRNEKEKVLIEGSINSLRISIAIKQADEIEKILCHKFMRFMMMRAENFFI LRRKPVDGYNISFLITNFHSEQMYKHKLVDFLITYMEEIDKEINEMKLAVNSRARISAEE FLKHFSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLV TMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTMPNTFKSLDSWRDEFLIQASPRDPEH FPFVVIGNKIDLENRAVSAKRSQSWCHSKGEIPYFETSAKEAINVEQAFQTVAKNALAQE TDVELYNEFPDQIKLSNDGNKEGCAC---FDARFPNMNQTRYCNQNYVDYNRCIDIEDYK PCEYFKRLYSETCPHALIQKWDALKEQ-------MPDHLGSDQRKVKDEKTDEKPIQALD EGDIALLKTYGVGQYTKTIKQCEEDIQNNLKKVNELSGIKESDTGLAPPALWDLAADKQT LQSEQPLQVARCTKIINADSDDPKYIINVKQFAKFVVDLGDQVAPTDIEEGMRVGVDRNK YQIHIPLPPKIDPSVTMMQVEEKPDVTYSDVGGCKEQIDKLREVVEVPLLHPEKFVNLGI EPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARA KKACIIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDT LDPALMRPGRLDRKIEFGLPDLEGRSHIFKIHARSMSVEKDIRYELMARLCPNSTGAEIR SVCTEAGMFAIRARRKMATEKDFLEAVNKVIKAYAKFSSTPRYMTYN---EKIHINIVVI GHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEANEMGKGSFKYAWVLDKLKAERERGITI DIALWKFQTAKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKEGQT REHALLAFTLGVKQLIIGVNKMDSTEPPYSESRFDEICKEVSGYIKKIGYNPKAVAFVPI SGFHGDNMLKMSWYKGWKIVSGDTLTDALDSIQPPKRPTDKPLRLPLQDVYKIGGIGTVP VGRVETGIIKPSMVVTFAPAGVTTECKSVEMHHESLTEGVPGDNVGFNIKNVSVKDIKRG MVAGDSKNDPPKGAKSFLAQVIILNHPGEIHAGYSPVLDCHTAHIACKFAELVEKIDRRS GKKLEDAPKMVKSGDAAIVNLIPSKPMCVEAFTDYAPLGRFAVRDMKQTVAVGVIKAVDK SE-AGGKVTKSAQKAELEALRQETEQLKNQIREARKAAADATLTQTTAQLESIGRIQMRT RRTLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAP SGSYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDNQIVTSSGDMTCA LWDIETGQQTTSFTGHTGDVMSLSLAPDFKTFVSGACDASAKLWDVRDGMCKQTFSGHES DINAITYFPNGFAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLMG GYDDFNCNVWDVLKQERAGVLAGHDNRVSCLGVTEDGTAVATGSWDSFLKIWNMSYAYLF KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTG---- -----------------------RDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLEARR EVKKEEGEAFAREHGLIFMETSAKTAANVEEAFINTAKEIYQKIQDGVFDINNEANGIKI GPQHSPANQSPGGGSNQGGGMTRGRIELGDITQHNIKQLKRLNQVVFPVTYNDKFYKDVL EVGELAKLVYYNDIVVGAVCCRIDNNDNQRRLYIMTLGCLASYRRLHIGTVMVEHVLDIC AKDGNYDNVFLHVQVNNEGAIKFYEKFGFEIVEEKQNYYKRIEPADAYVLQKSFRNMPKQ IKEIKDFLLTARRKDANSVKIKKNVKFKVRCSRYLYTLVIQDREKADKLRQSLPPGLAVK ELKMSKINRDNLRESINNIFEKKRKFTESIELQIGLKNYDPQKDKRFSGTIQLRHIPKPK MKVCILGDQIHCDQAKANEMPCMDADMLKKLNKDKKLVKKLAKRYDAFLASETLIKQIPR LLGPGLNKAGKFPTPISHNQSLVSKVQQVKGTIKFQMKKVLCLSVCIGHINMSQEEVYTN VNLAINFLVSLLKKNWQNVRTLHIKSSMGPVQRIYMADADKLNIDSVIARLLEVRGSRPG KNVQLTEGEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN IKLWKTFTDCFNCLPISAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLNAGRPVTPPRGNQKAK GKIMFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEIVGTNVSTT FIQCPTEPKKTLGIKLPFLVMIIKNLKKYFTFEVTVLDDKNVKRRFRASNYQSTTRVKPF ICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDEL PAEFKLYLPVQNKMTTESIQNLKDPFAESGEIHIRIQQRNGRKTLTTVQGIHPKYDLKKI VKACKKQYACNGTVSINPEYGECIQLQGDQREKIKEFMMQVGLPEQIKVHGFSALFNFQS LLTVLLLLICTCTYLRSIMPSIIDRNKTGFLGIFWKFARIGERKSPYVGACCVAMAISIL FWSTARLSASLVRQLPSAVNKKYAVGTTFAAAKKFSTSSEVSSILEDRILGTTNVNLEET GRVLSIGDGIARVYGLKNIQAEEMVEFSSGLKGMALNLEPDNVGVVVFGNDKLIGEGDIV KRTGAIVDVPVGREILGRVVDALGNAIDGKGAIKTPARARVGVKAPGIIPRTSVNEPMQT GIKAVDSLVPIGRGQRELIIGDRQTGKTAIAIDTIINQKRFNDGSDEKAKLYCIYVAIGQ KRSTVAQLVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCAMGEYFRDNGMHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNNDNKGGSLTALPVIE TQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTKAMKQVAG SMKLELAQYREVAAFAQFGSDLDQATQNLLNRGVRLTELLKQGQYVPMAIEEQVAVIYAG VRGHLDKLDPSKITSFESEFLQHLRSSQTNLLKTIATEGKISDASEEALKGVVTSFLQSY MEALYSIPFTVLECPNLKLRKPSWLRQPSAMFMFTLVLLSYFLVTGGIIYDVIVEPPSIG STTDERGNSKPVAFMPYRVNGQYIMEGLASSFLFTLGGLGFVILDMTNKPLMPRLNRILL LSIGFIAVLISFFMCRVFMRIKLPMPKIKRSRKPPPEGWELIEPTIDELDAKMREAETDP HEGKRKVEAMWPIFRLHHQKSRYIYDLFYRRKAISRELYEYCLKENIADKNLIAKWKKQG YENLCCLRCIQTRDTNFGTNCICRVPKPKLESGKIVECIHCGCRGCSGEYAQVSKMLGNG RLEAMCFDGNKRLCHIRGKLRKKVWINTGDIILLGLRDYQDTKADVILKYTPDEARNLKA YGELPENSKFH---------------LVRFLMKLSHETVTIELKNGTQVHGTVTGVDVCM NTHLKAVKMTIKNKDPVQIDTLSIRGNNIRYFILPDSLPLDTLLIDDTPKARQRK----K PKSEMTPEDMAAREQEEFNTGPLSVLTQSVKNNTQVLINCRNNKKLLCRVKAFDRHCNMV LENVKEMWTEVPKTGKGKKKSKPVNKDRYISKMFLRGDSVILVLRNPLPILIDARGHLLG RLSATVAKTLLQGQRVTVVRCEGINISGKYHRQKNRYLSLIKKRCNVKPSRGPFHFRAPR KIFYRTVRGMIPHRTVRGKEAMARLSVFEGIPAPYDKKKRVVIPSALRVIRLNPQRKYCE LNRISSEIGWKYSHVIETMEQRRKTRSSQYFSQKKNQAKLKAQARKTAEFDKILAANGYQ GDVEKGKKLFVQRCKQCHNVDKGGKNATGPALHGLWGRKTGQAPGFGYTTANVNKGITWN KDTLFEYLENPKKYIPGTKMVFAGLKKPKDRADLIAYLESTTKIYVEQTLALIKPDCISE EIEDIILRSGFAIIKKRRVHLTPEQASDFYAEHYGKLFFPSLVAYMSSGPIIAMALSRDR AISYWRELIGPTNTYKARNTHPDSLRAIYGTDDQRNALHGSDSFSSSQREIRFFFPDSIV EPVAVGQAAKDYLSKVVNPTLLKGLTSLCKQKPQDPLVWLADWLIENNPNKPRV-MFEAR LVQGSLLKKILEATKDLLNEALWDCSTNGITLQAMDSSHVSLVSLKMRSDGFETYRCDRN ISLGMATASMSKILRCAGNDDIVTVKAEDAGDKVTFVFESPQGEKMSDYEMKLIDLDAEH LGIPDTEYSCVVKMPSAEFQRVCRDLSQIGESVVITCTKEGVKFTATGDLGTGNIKLAQN INTDKEEESVVVEMSQGVCLTFALRYLNFFTKATPLSPQVTLSMSQDVPLVVEYKIGDMG QLRYYLAPKIEENDD--------------KGRIVAVIGAVVDVQFDDALPPILNALEVKD RSPRLVLEVAQHLGENTVRTIAMDGTEGLIRGQQCIDSGTPIRIPVGPKTLGRIINVIGE PIDERGPVPTDKFSAIHQEAPEFIEMNVQQEILETGIKVVDLLAPYAKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMITSKVISLTDDTSKVALVYG QMNEPPGARARVALTGLTVAEYFRDMEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIA ELGIYPAVDPLDSTSRILDPNVVGAEHYAIARSVQKILQDYKSLQDIIAILGMDELSEED KLTVSRARKIQRFLSQPFQVAEVFTGSPGKYVPLVECIKGFQRILKGELDHLPEIAFYMV GPIEEVISKAEKLAEDQMLMPKKNRVTIYEYLFKEGVMVAKKDFFAPRHPNINVPNLHVI KALTSLKSRGLVREQFAWRHYYWYLTNEGIQFLRDFLHLPPEIVPATLKRQGAHADRGEY RKSGGGDKKADVGAGANMGKANSKLKPEILEDLRKNTEFTDEELQEWYKGFLKDCPSGHL SVEEFKKIYGNFFPYGDASKFAEHVFRTFDTNGDGTIDFREFICALSVTSRGKLEQKLRW AFSMYDLDGNGFISRQEMLEIVTAIYKMVGTVMKMPEDESTPEKRTEKIFRQMDKNLDGR LSLDEFIEGAKSDPSIVRLLQCDPMSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNL TGLIEQVPHYRQALDMILDLEPDEDLEDNPNQSDLIEQAAEMLYGLIHARYIMTNRGIAQ MIEKWQQGDFGYCPRVYCENQAMLPIGLSDVPGEAMVKLYCPKCQDVYTPKSSRHHHTDG AYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPLAYQLQYQAAANFKFSHTNSKR -----GIRAGTRRLLACPFRKRGVVHTSRYMHVFKRGDYVDIKADPRIQKGMPHKYYHGK TGRVFNVARRALGVTVNKRVRTRIMAKKISVRIEHVKPSRCRDDFIKRVKENQRLIEEAK KKPQLKRQAAQPKPGFFVRTDKNKPQLIEPIPYEFI-QSRSHWKDVGQQKENMAWNDIAL RAAKASFFTEIMKGFGMTFAQQLKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAICPAQAITIEAEPRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEY STETREELLYNKEKLLSNGDKWEVEIAANLQADYLYRMASQAKVAKSDGKNNHDNDKEQQ EAIEQIDEVQNEIDRLNEQASEEILKVEQKFNKSRQPFFQKRSDLIAKIPNFWFTAFVNH PQVSALLNEEDEEALQYLTKVEVQEFEDIKSGYKINFSFDTNPYFDNEIISKEFHLNSSK STTIKWKSGKAVTHVRRKRNHDEQESFFNWFSDHNDAGADELGEVIKDDIWPNPLQYYLV SDLGDDDI--EGLDDDGTKLSREEELLLQDFSRNVSTKSSALFYGNALIVSAIPIWLFWR IHQMDLWFLFVIFSLVSTYLVAYAYKNVKFVLKHYIAQKREEGITKEMMSKLSEDKEMTK KEKDERVLWKKNEVADYEATTFSIFYNNALYLVLLIVFSFYILKNMNPSV---------- -----------ATQGKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQT VCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVKELQRQ ASPNIVIALAGNKADLRMVEFEEAQAYAEENSLLFMETSAKTAMNVNDIFLAIAKKLPKN EAGVRLNNDSMAEYLASIFGTEKDKVNCSFYFKIGACRHGEKCSRLHNKPTFSQTVLLLN LYLNPQNTALILVDDMQAQQEFDDFFEEVFTELEDKYGEIEEMNVCDNLGDHLVGNVYVK YRYEEDAEKAVNDLNNRWFNGRPVCSELSPVTDFREACCRQYEMGECTRGGFCNFMHLKP ISRELRRELYSRRR--RSRSRERRRSRSRD--------RSRDR--MFLTRSEYDRGVNTF SPEGRLFQVEYAIEAIKLGSTAIGIQSSEGTVLAVEKRVTSPLIEPSSIEKIMEVDSHIG CAMSGLIADSRTLIDRARVEAQNHWFTYNEKMSVESVTQAVSNLALAFGDDDAEPGAMSR PFGVALLFAGMDEKGPQLYHMDPSGTFIQYDAKAIGSGSEGAQQALQEVFHKSITLKEAC KSALTILKQVMEEKLNSTNVELATVTPERNFHMFTKEELENIIKDIAQKSWELANNIETV NSIDDIYRYDRKQHQDILTAKPWEKDNHHFKHIKISALALLKMVMHARSGGNLEVMGLLL GKVDGNTMIVMDGVALPVEGTETRVNAQAQAYEYMAAYTDAAKQVGRLENAIGWYHSHPG YGCWLSGIDVNTQMLNQQFQEPFVAIVIDPVRTISAGKVNIGAFRTYPKGYKPPDEGPSE YQSIPLNKIEDFGVHCKQYYSLDISYFKSALDCKLLESLWNKYWVNTLSSSSLLTNAEYT THQIFDLADKLEQSEAQLGRGSFMEKKSEDKLLKAKKDGCKTTIEAIHGLMSQVIKDRLF NQV-GLPRRILKETQRLIQEPVPGISAVPDENNGRYFHVVIKGPAESPYHSGMFQLELFL PEEYPMSAPKVRFMTKIYHPNIDKLGRICLDILKEKWSPALQIRTVLLSIQALLSAPNPD DPLSNDVAEQWKANEQLALETAKEWTQKYAAAENEILDYE-DEAETTKDVKGTYVSIHSS GFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILSMDVLCQAKSGMGKTAVFVLATLQ QLEPVDGQVSVLVLAHTRELAFQISKEYERFSKYMNNVKIAVFFGGMNVKKDEEVLKKNC PHIVVGTPGRLQALIKSLSLKHVKHFILDECDKMLAELDMRRDVQEIFRMTPHEKQVMMF SATLSKDVRPICKRFMQDPMEVYVDDDSKLTLHGLQQHYVKLKDNEKNRKLFELLDVLEF NQVIIFVKSVQRCMALAQLLQEQNFPAIAIHRAMTQEERLSRYQQFKDFQKRILVATNLF GRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITLISDENDAKIPPSFSDLG KSSRDIFDEGFNYGFTKLEAKTKTDSGVNFTVSGNSSTDTGKVSGKFETKYKWNEYGLTF TEKWNTDNVLNTQITIEDQLAKGLKLAFDTSFAPHTGKKSGKIKSGFKNDNVNLNCDVDF DFAGPTIHGAAVLGYTGWLAGYQMSFDKSKLTKSNFAVGYTAGDFTLHTSINDGQEFGGS VYQRVNKDLETAVNLAWTSGTNATKFGLGAKYTLDRNSSINAKVNNSSQVGLGFTHKLKD GIQLTVSSLIEGKNINAGGHKIGLGLEFEADSVREKALADYRKKLLEHKELEARLKEMRE TLKDLTKQYDKSENDLKALQSVGQIVGEVLKQLTEEKCKLKTDTNDTWIMRAEGRKKSYW FLADDWFKADKTDCLICRHLPREVDPLVYNMSAEDPGSVSFNQIGGLSEQIRELREVIEL PLLNPELFQRVGITPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSAIVDKYIGES ARLIREMFAFARDHAPCIIFMDEIDAIRRFSEGTSADREIQRTLMELLNQMDGFDALGQV KMIMATNRPDTLDPALLRPGRLDRKIEIQLPNEQARMEILKIHASPIAKHGEIDWEAVVK LSEDFNGADLRNVCTEAGMFAIRSERDYVLEEDFMKAVRKVADNKKLESKLDYKPIMPES LVSVLGKLYDEYVHSTPKKLKIIDAYLVYVLLTGIIQFVYCALVGTFPFNSFLSGFISTV GTFVLGVCLRLQVNPLNKSDFSGISPERAFADFVFAHVILHLVVVNFIGTFTSPSQLLPL ELVDKCIGSRIHIIMKNDIEIVGTFWGFDDYVNMVLEDVSEFESTPEGRRVTRIDKILLN GNNITMLVPGGEGPEVIDHYENPRNVGSMDKKDKDVGTGLVGAPACGDVMKLQIKVDDDG KIVDAKFKTFGCGSAIASSSLATEWVKGKSVDEAIKIKNTDIAKELSLPPVKLHCSMLAE DAIKAALSDYKIKNKMLVLVLGDLHIPHRCNSVPSRFKKLLVPGKIQHILCTGNLCTKES FDYLKTLASDVHVVRGDFDENMNYPEQKVVTVGQFRIGLCHGHQVVPWGDNESLAMVQRQ LDVDILISGHTHKFEAFEHEGKFYINPGSATGSYNPLDSSVVPSFVILDIQQSTVVAYVY KLVNNDVKVERIEYRKMGKFIKSNKVVLVLNGRYAGHKGIIVKNFDEGATDKPYGHALVA GIAKYPQKLTKKMTKRKLSLRSRIKTFVKVYNYNHLMPTRYSLVGLDKNVVNRDAAKDPA LKAKARKEVKAKLQDRYKNGRNRWFFRKLKFXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-- -----KTPLNARQKALNAKKAALKGVHNKRIRKVRTTPSFKRPKTMKLPRAPKYVRSLTT KR-GLDKYKIVKYPLTTETAMKKIEDNNTLVFIVDRRANKYTISNAVKALYSIEVAKINT LIRPDGEKKAYVRLPSDYDGLEIASKV---MPSKQRMRVASEKASKNVTARGNVPKTLKP GDEKYPVGPWLLGLFVFVVCGSAVFQIIQSIRL-----WTAVASWRWIANDENCGICRMP FDGCCPDCKLPGDDCPLVWGQCSHCFHIHCIVKWLNSQQVHQLCPMCRQEWKFKEMIRFV LIQNRAGKTRLAKWYMHFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIVYRRYAGL YFCICVDVNDNNLAYLEAIHNFVEVLNEFFHNVCELDLVFNFYKVYSVVDEMFLAGEIRE TSQTKVLKQLLMLSSLEKPTIFTKIIDKTIPADILYEDKQCMAFSDVNPTAPVHFLVIPR KPLTGISEDQELLGHLLLVAKKLAEDDKGYRIVINNGVEGSQSVYHLHIHVIGGRQMNWP PMGGLLSYFSGLFGSKERRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVTYKN LKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSMDRDRIGISKQELVSMLEEDELKKAV LVVFANKQDIEGAMTVSEVANALGLSALKNRKYQIFKTSAIKGLGLDEAMEWLSDTVQQQ K-LYFHIGETQKKCFIEEIPDETMVVGKYKVEIFDRNVNDYIPTVYGLGMHVEVRDPDDK IILSRTYAAEGRFTFTSHTAGEHVVCLHSNSTAWFSAGQLRVHLDIQVGEHAVDYQQVQA KDKLSELQLRVRQLLDQVEQITKEQNYQRYREERFRQTSESTNQRVLWWSIAQTVILLIT GFLQMKHLKSFFEAKKLVMFYHVSLEHEILLHPRYFGPNLLNIVKKKLFTEVEGTCTGKY GFVIAVTTIDNIGAGLIQPSRGFVLYPVKYKAIVFRPFKGEVLDAVVTQVNKVGLFTEVG PLSCFISRHSIPADMEFDPNSNPPCYKTKDEDIVVQQDDEIRIKIVGTRVDAKDIFAIGT LMDDYLGLVSRLFCKAVFVGYKRGLRRQYESTSLLRIDGVNTKKDTSFYLGKKCAYVYRV KKTTSTPGKRAEHKVKVIWGKVTRPHGCSGTVRAKFRTNLPSKAIGHRIRVMLYMAKKTY DLLFKLLLIGDSGVGKTCLLFRFSDDAFNTTFISTIGIDFKIKTVELGGKKIKLQIWDTA GQERFHTITTSYYRGAMGIMLVYDITNAKSFENISKWLRNIDEHANEDVEKMILGNKCDM EDKRQVPKERGNAIAIEHGIPFLETSAKANINVEKGFMELAQAILNKMPQNEHIELHRKR HGYRLDYHEKKRKKEGRMGHKMAEKARKLRGIKAKLHNKKRHSEKVQMKKTLKMHEERQT KQKSDDNVPEGAVPAYLLDREGQSRAKVLSNMIKQKRKEKAGKWDVPLPKVKGMSEAEVF KVVRTGKTRRKGWKRMVTKVTYVGENFTRKPPKFERFIRPMGLRFKKAHVTHPELKATFC LPMIGVKKNPSSTMYTSLGVITKGTIIEVNISELGLVTQGGKVIWGKYAQVTNNPENDGC INAVLLV-AARPLVSVYNEKGEKTGTNVALPAVFKAPVRPDVVNFVHFEMMKNTRQPYAV SQKAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRK INTTQKRYAICSAVAATGVPALIMSKGHRIEETPEIPLVVSDKVEEFKRTKEAVQLMKKL NAWIDIQKVYASKRMRPGKGKLRNRRQMMRKGPLIVFNKNNGICRAFRNIPGVNLLDVSR LNLLKVAPGGHVGRFTIWTEGAFKALDGLYGTWKKASTEKNHFNLPATKMTNTDLLRLLR SDEITSVVRPAIHDRKRRTLKKNPLKNRSVMIRLNPYAKVQHK---REKDRTNLLNKKRG LPPVQPKSKSIQRNAAK---EQELATRTLHIQSKRFYLDVKQNRRGRFIKVAEVGAGGKK SRLLLAMSSAAEFRDYLTDFTEHYASLGPTNTENPPEDGKLKSELIVKDNRRYYLDLKEN QRGRFLRVSPRGGPRSQIAIPAQGMIEFRDALTELLDEFGTDDQEPQSDLPESRSMRVEN KMFYFDVGSNRRGVYMRISENNFRTAITIPERSWGRFRDILSEFSDK--------QMRAT INQKLVETGERDRLKELLRTRLIESGWRDQLKSFCKDVVQQKGLAHVTVDDLVAEITPRG RALVPDKVKEELLQRIKMFLSQQANMNIRCARPEDLMNMQHCNLLCLPENYQMKYYFYHG LSWPQLSYVGETSDGNIVGYVLAKMEEDPEDSIPHGHITSLAVKRSHRRLGLAQKLMDQA SRAMVECFKAHYVSLHVRKSNRAALHLYTNTLKFKISEIEPKYYADGEDAYAMKRQL--- ----MSHTILLVQPHSRPDTRTYSDYESLNECLEGVCKIFEEHLKRLNPDQQSITYDISQ LFEFIEQLADLSCLVQQKSSGLYVPHNKEWVKQGIYSMLRKQAAKVA---EEKKVDTESK RVHTYPLIRHSDMNDEMKTEAMELCVTACEKFSANNENAAKMIKETMDKKFGASWHAVVG EGYGFEITHEVKNLLYMFFGGNMAIMIWKCSMSHRKFSAPRHGSKGFLPKKRSRRHRGRI HAFPKDDPKKPVHMTAFIGYKAGMTHIVRDVDRPGSKLNKKEVVEGVSIIETPPMMVVGV TGYIETPEGLKTFKTLWAEHLSEECRRRFYKNWSRSKKKAFTKNAKKWKDEAGKKLIESD FNKMKKYCKVIRVIAHTQTKLLRHLQKKAHIVEVQLNGGSIADKVDWARQQLEKPVPVNQ VFEQDEVLDIIGVTKGKGFKGVTARWHTKKLPRKTHKGLRKVACIGAWHPSRVQFSVARA GQKGYHHRTELNKKIYRIGLGIHTKDGKVVKNNASTDFDPVTKAITPMGGFHHYGEVNND FLMIKGAVVGTRKRVITLRKSLLTTFRRKHTEKVVLKMIDTTSKLGHGRFQTHEEKKAFM GPLKKDMQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLG LWDTAGQEDYDRLRPLSYPQTDVFLICFSLISPASFENVRAKWFPEVSHHCPQTPIILVG TKLDLREDKETIEKLREKKLAPITYPQGLAMAKEIGAVKYLECSALTQKGLKFVFDEAIR AVLCPKPKPPKKKNCKIL-FDSSMKKKKKKKTPFDPDSVMQPDKIDDGGLKKKKKKKKPT D----ENTEPSAETDSKKKKKKSGTDRDYTYDELLQRVFDIMREKNPEMISGEKKKFVMR PPQVLRVGTRKSSFANFTDICRLLHRQPKHVLAFLLAELGTSGSVDGNNQLIIRGKYNQK QIENVLRRYIKEYVTCHTCRSPDTLLQKDTRLYFLQCETCGSRCSVASIKSGFVAVTGKR AAIRAKTTYDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVSRPSDK DYSLHRLILGTHTSDEQNHLLIASVQLPNDNVQFDASHYDSEKGEFGGFGSVSGKIEIEI KINHEGEVNRARSMPQNPFIIATKTPSCDVLLFDYSKHPSKPDPSGECHPELRLKGHQKE GYGLSWNPNLNGHLLSASDDHTICLWDVNAGTKDSKTVDAHTIFTGHTSVVEDVAWHLLH ESLFGSVADDQKLMIWDTRSNNPNKPSHTVDAHTAEVNCLSFNPYSEFILASGSADKTVA LWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQSAEDA EDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEEPDTPAS DLE-PLPSRARVYPDINTHKPKDYWDYESHVVEWGNQDDYQIVRKLGRGKYSEVFESVNI TNNEKCVIKILKPVKKKKIKREIKILENLRGGTNIITLLAIVKDPVSRTPALIFEHVNNT DFKQLYQTFTDYDIRFYLYELLKALDYCHSFGIMHRDVKPHNVMIDHENRKLRLIDWGLA EFYHPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPFFHGHDNY DQLVRIAKVLGTDDLYAYIEKYQIDLDQRFNDILGRHSRKRWERFVHSENQHLVSPEALD FLDKLLRYDHQERLTAREAMDHPYFYAIVQEQAPESLLKKRKENKVSRQQKKKLIFKRAQ AYVKEYRVMEKQARGLLKVAEKYDNFYVPPEPKVVYVMRIRGINNIHPRPRKIMQLLRLR QINNGIFLRMNKATANMLKLAEPYITWGTPNLKTVRDLIYKRGYAKIKGSRIPLTDNALI ENVLGKYNIMCMEDLIHEICTCGPRFREVSNFLWPFKLSNPNGGWRKKLNHYNDGGDYGN RDEDINKLLRX-MQFMLLFSRQGKLRLQKWFVAHTDKVKKKITRELVTLVLGRKPKMCSF LEWKDLKVVYKRYASLYFCCAIEPEDNELLTLEIIHRYVELLDKYFGSVCELDIIFNFEK AYFMLDEFLLGGEVQETSKKNVLKAIAAQDLLQEETPQGFFDDHGLGMSKAHPPELKKYM DKRLTLKLNGGRQIVGTLRGFDPFMNLVVDESMEKLKTGGEQPIGMVVVRGNSIVLLESL ERVEFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTI RLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERGSDVIIM LVGNKTDLSDKRQVTTEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMEQTEP KKMTEVKLKETPAEPQAMAIKYDMAVGIKKGHKVTPKKNKANRMKGRNTKKNKFVRDLVR EIVGLSPYEKRCQELLRVSREKRALKFCKKRLGAHTRGKKKREEMQAILNAIRKAMVDEA TKKSLAQIPLLKTKAGPRDGELWVTRLKEEYQALIKYVQNNKDSDNDWFRLESNKEGTRW FGKCWYVHELLKYEFDLEFDIPITYPTTAPELALPELDGKTAKMYRGGKICLTDHFKPLW ARNVPKFGIAHALSLGLGPWLAVEVPDLIQKQIITHK-GLLDFDFLDEVRRMNKRQLYYQ ALNFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFYRGDLLLLTNHPEEPIRVGE IVVFKIEGRDIPIVHRVLKIHEKEDGSLKFLTKGDNNSVDDRGLYAQGQFWLEKKDVVGR ARGFLPYVGIVTILMNDYPKFKYLVLACLGIYVLIHRELSKMNPEYDYLFKLLLIGDSGV GKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYR GAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTAKKVVDYTTAKEY ADQLGIPFLETSAKNATNVEQAFMTMAAEIKNRMGPVTAAPSVKINSSTPVKQSGGGCCE ESLGEEVLRMSTDEIVSRTRLLDNEIKIMKSEIMRISHELQAQKEKIKENKEKIKVNKTL PYLVSNVIELLDMDPQDQEEEDGANVDLDAQRKGKCAVIKTSTRQTYFLPVIGLVDEEKL KPGDLVGVNKDSYLVLETLPAEYDSRVKAMEVDERPTEQYSDVGGLDKQIQELIEAVVLP MTHKERFEALGIQPPKGVLLYGPPGTGKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGA KLVRDAFALAKEKAPAIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQMDGFQPNQM VKVIAATNRVDILDPALLRSGRLDRKIEFPHPNEEARARILQIHSRKMNVSKDVNYEELA RCTDDFNGAQLKAVCVEAGMIALRREAAELSHEDYMDAIIEVQAKKKTNLQYYAKDAADQ NFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRQDKRVKLQIWD TAGQERYRTITTAYYRGAMGFLLMYDVTNEESFNAVQDWCTQIKTYSWDNAQVVLVGNKC DLEDERVVSTDRGKQLADQLGLEFFETSAKENINVKSVFERLVDIICDKMSESLDSDPTK GTRLTENTNAQNAGCSCRTINKLAVTRDYISQPRITYKTVSGVNGPLVILDDVKFPKYAE IVNLTLADGSQRSGQVLEVSGSKAVVQVFEGTSGIDAKHTTCEFTGDILRMPVSEDMLGR VFNGSGKPIDKGPAVLAEDFLDIQGQPINPWSRIYPEEMIQTGISAIDTMNSIARGQKIP IFSAAGLPHNEIAAQICRQAGLVKLPGKSVMDDHEDNFAIVFAAMGVNMETARFFKQDFE ENGSMENVSLFLNLANDPTIERIITPRIALTTAEYMAYQCEKHVLVILTDMSSYAEALRE VSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLT GYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGDDMTREDHADVSNQLYACYAIG KDVQAMKAVVGEEALTPEDLLYLEFLIKFEKNFISQGHYENRTIFESLDKGWQLLRIFPK EMLKRIPQHTLAKYYPRDA-GPGFIGIRFCKECNNMLYPKEDKDSKILLYACRNCDYQQE AENRCIYVNKIMHEVDELTQIVGDVIADPTLPRTEDHHCPKCSHKEAVFFQSHSSKAEEG MRLYYVCGNSQCLHRWTEMPSYKVADISLAEWGRKAIEIAENEMPGLMSMRRKYGPSKPL KGARIAGCLHMTVQTAVLIETLTELGAEVQWSSCNIFSTQDHAAAAIAKTGVPVYAWKGE TDEEYIWCIEQTIYFADKKPLNMILDDGGDLTNLIHSKYTDILPGIKGLSEETTTGVHNL YKMMKDGKLKMPAFNVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGKVALVAGYGDV GKGCAQALRAFGARVIVAEIDPINALQAAMEGYEVSTVDEAVKEARIYVTATGCSGILRP EHFQQMLEDSVVCNIGHFDCEIDVKWLNENSSKKEQIKPQVDRYTLKSGRHIILLAEGRL VNLGCAHGHPSFVMSNSFCNQVLAQIELWTKPGQYEVGVHLLPKILDEEVAHQHLEHLGV KLTKLSEEQAKYLGLPQNGPFKPNIYRYAEDQEQQPAQTVEEPLDLIRLSLDERIYVKMR NDRELKGRLHAYDQHLNMIMGDVEETVTTVEIDEETYEEIYKSTKRNIPMLFVRGDGVIL VSPPMRT-SISNVENLSPQTIRLVSKELGELTKSPPEGIKVFLNEEDITDIQASIVGPAG TPYAGGLFRMKLVLGKNFPSEPPKAYFLTKIFHPNVASNGEICVNTLKKDWKAELGIKHI LLTIKCLLIVPNPESALNEEAGKLLLEQYDDYSSRAKMFTEIHAQ--------------- -NPFGLEINPARRIKAAADETSCEFGSTKYFALCAFGGVLSCGITHTAVVPLDLVKCRIQ VDAGKYKNIVNGFRVTLAEEGFRALGKGWAPTFIGYSMQGLCKFGFYEVFKDVYSKMLGE ENTFLWRTSLYLAASASAEFFADIALCPMEAIKVRIQTQPGWSNTLREGFPRILQEEGMT GFYKGLVPLWCRQIPYTMMKFACFERTVEAIYKFVVPKPRSDCTKGEQLVVTFAAGYIAG VFCAIVSHPADTIVSKLNQDKGSNFMDIAKRLGFMGMWKGLMPRIIMIGTLTALQWFIYD SVKVFFRLPRPPPPEMPESLKKKL-HWKVERVLMLSMVPVLPAALFIVIDHLMSVVFLHG FWGMEGVLTDYLYISIIAFAGLVNFNYNDVGICKAVSMLWS--NEVQDEDASNLVFPKEF ENAETLLISEVQRKQQNESAEDEQELSEVFMKTLNSCQRFSKFKNRETIAAVRSLLMQKK LHKFELAALANLCPESADEAKSLIPSLEGRFEDEELTQILDDIKTKRSFQYNLQPHLSKQ DLNTLDVKKLTPLTPDVISRQATINIGTIGHVAHGKSTVVKAISGVQTVRFKNELERNIT IKLGYANAKIYKCDYERCPRPGCYRSCGSSKEDVFPCDRPGCGKFRLQRHVSFVDCPGHD ILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAVEIMKLKHILILQNKIDLVKEAQ AKDQYEQILAFVKGTVAEGAPVIPVSAQLKYNIDVVCEYVTKRIPVPIRDFTSEPRLIVI RSFDVNKPGCEVDDIKGGVAGGSILRGVLKVGQEIEVRPGIVSRDEDGKLTCRPILSRII SLFAEQNDLQYAVPGGLIGVGTKIDPMLCRGDRMVGQVLGAVNALPDIYTELEISYFLLR RLLGVKTEGDKKGAKVQKLTKNEILMVNIGSLSTGGRVQAVKADLAKIGLTTPVCTEINE KIALSRRVEKHWRLIGWGQIRRGVKVVPMADLLLDSNIRIWVFLPIVVITFLVGIIRHYV TILLSSEKKSDLQQVADSHALMRSRILRENGKYIPKDSYLIRKSFFNHEEKGFFVKNPMT DPSMMTDMMKGNITNVLPMIVIGGWINWAFSGFLTTKVPFPLTLRFKPMLQRGVELQSLD ASWVSSASWYFLNVFGLRSMYTLILGQDNAADQTRMMQEQMSGSAMMAPQDPMKAFKAEW EALEISNHDWILDGVEEEL-MFLWDWFSGVLNFLGLWKKSGKLVFLGLDNAGKTTLLHML KDDRMAQHVPTLHPTSEDLSMGGMRFTTFDLGGHRQARRVWKDYFPAVDGIVFLIDACDR ERFVEAKAELDSLLTDEQVANAPILVLGNKIDKPGAASEDEIRHWFGLNGQTTGKGTVSR SELRPMELFMCTVLKRQGYGEGFRWLAQYINIIRRNRPGTKARDWGNWQDESFEEMDSTL AVQQFIQQAIRKDFMNIDDILTPPEGQDEGVWKYEHLRQFCMELNGLAVRLQSECNPETC TQMTATEQWIFLCAAHKTPKECPAIDYTRHTLDGAACLLNSNKYFPSRVSIKESSVAKLG SVCRRVYRIFSHAYFHHRALFDEYENETYLCRRFTSFVTKYNLMSKDNLIVPILEDQMPC IKLQSSDGEIFEVDVEIAKQSVTIKTMLEDDEDEEEPVPLPNVNAAILKKVIQWCTYHKD DPPPPEDDENKEKRTDDICSWDAEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMI KGKSPEEIRKTFNIKNDFTPAEEEQVRKENEWCEEKXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSASAVYI CDVKGKVLISRNYRGDIDMSVIDKFMSLVMDKEEEGNVTPIIEHNNVTFIYIKYNNLYCV ATSKKNSNVALVFSFLHKIVQIFIEYFKEMEEESIRDNFVCIYELLDEVMDFGFPQTTDT KILQEFITQEGHKLEVAPRPPMAVTNAVSWRSEGVKYRKNEVFLDVIESVNLLVSANGNV LRSEIVGSIKMRVFLSGMPELRLGLNDKVLFESTGRGKSKSVELEDVKFHQCVRLSRFEN DRTISFIPPDGEFELMSYRLNTHVKPLIWVESVIERHAHSRVEYMIKAKSQFKRRSTANN VEIIIPVPTDADSPKFKTTVGNCRYTPEISSVIWSIKSFPGGKEYLMRAHFGLPSVETED SEGRPPIQVKFEIPYFTVSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRT-MSVLQK IAEIEAEMARTQKNKATSGHLGMLKAKLAKFRRELIEPKGGGGGAGEGFDVAKTGDARIG FVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKVQLLDLPGIIEGAKDG KGRGKQVIAVARTCSLIYIVLDVLKPLQHKHLIEKELEGFGIRLNKTPPNIVFKRKDKGG LNLTSTVAQSELDNDLVKTILNEYRISNADITLRIDATAEDLIDVIEGNRVYIPCIYILN KIDQISIEELDLVYKVPHCVPISAHHKWNFDDLLEKMWEYLALVRIYTKPKGQLPDYTAP VVLREGKTTIEDFANKLHRSIMKEFKYALVWGSSVKHQPQKVGKTHILQDEDVVQIVKKM AKHHPDLIFCRKQPGVAIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGSYQGRCVIC GGPGVSDAYYCKECTIMEKDRDGCPKIVNLGSAKTDLFYERKKYGFKKR----------- --KSELRKIPIPSNRYTPLKKNWLKIFTPIVEHLHLQIRFNLKTRNVEIKTCKATTDIRA LQKAADFVQAFVYGFEVEDSLALVRLDELYLETFDVTDVKPLKGNHLSRAIGRIAGHNGK TRFTIENVTKTRIILAASKVHILGSFQNINMARTAICNLILGSPPSKVYGQMRTVASRVS ERRIKVDKPVVELDGDEMTRIIWEKIKEQLIFPYLDLDCKYYDLGLPYRDQTNDQVTIDS AEAIKKYNVGIKCATITPDEERVEEFKLKKMWLSPNGTIRNILGGTVFREPIICQKIPRL VPGWTQPIVIGRHAFGDQYRATDFVAPGPGKLEMIYTPNGGQPNKMTVYDFKDGGGVALC MYNTDESITNFAHACFQYAIMKKWPLYMSTKNTILKRYDGRFKDIFEEIFAKQYKSKFDE LKIWYEHRLIDDMVAQCLKSSGGFVWGCKNYDGDVQSDIVAQGYGSLGLMTSVLVCPDGK TIEAEAAHGTVTRHYREHQKGNQTSTNPIASIYAWTRGLEHRGKLDGNQDLQRWAQLMEK ACVDTVDSGKMTKDLAGCIHGLKNVTPSHYLNTMDFLSAISEEFEMGKMLSKIFGNKEMR ILMLGLDAAGKTTVLYKLKLGQPVTTIPTVGFNVETVTYKNVKFSVWDVGGQDKIRPLWR HYYTGTQGLIFVCDTADRDRIDEARNELHRIINDREMRDVIILVFANKQDLPDAMKPHEV TEKLGLTRIRDRNWYVQPSCATTGDGLHEGLTWLTSNHKSFGDLKSKDGLSSLNTFFADR SYIDGYSPSAADAVVFEALASPASNYPHALRWYNHIKSYGDLRKSFPGTRKPVTSYGNST -DGDDDDDDFDLFGGALEELKKKRVAEYEARKAPTVIAKSSIILEVKPWDDETDMKEVEK NVRSIEADGLRWAASKLVPVGYGINKLQINCVVEDDKIGTDFLEEEITKFEDLVQSVDIA GFNKIKVQEVREVTRIERIGAHSHIRGLGLDDALEARAVSQGMVGQAAARRAAGVILEVI KEGKIAGRAILIAGQPGTGKTAIAMGMAQALGSDTPFTSIAGSEIFSLEMSKTEALTQAF RKSIGVRIKEETEIIEGEVVEIQIDRPATGTGAKVGKLTLKTTEMETIYDLGQKMIESLT KDKVQAGDIITIDKASGKITKLGRSFTRARDYDAMGPQTKFVQCPEGELQKRKEVVHTVT LHEIDVINSRTQGFLALFSGDTGEIKSEVREQINSKVAEWREEGKAEIVPGVLFIDEVHM LDIECFSFLNRALESDMAPILIMATNRGITKIRGTQYNSPHGVPIDLLDRLLIISTSPYE EKEIKQILKIRCEEEDVEMSDDALTVLTRIGMETSLRYSIQLITTANLVSRKRKATEVEV DDIKRVYSLFLDESRSTQFLKECQEEFMFNEMAEYDLTTRLGEYLDRHLVFPLLEFLSVK ELYDDKEMLKGKLDLLSNTNMVDFAMDVHQNLYPDQQVPPVLKDKRGKVVNELKTLQAET DVITKIFEDPEVTIQN-RDGRQLCDFLYQEKGFKPEMVETLYNYAKFQYECGNYSGAAEY LYFVRALVTPNDKNFMNALWGKLASEILMQNWDVALEDLNRLKDIIDGDLQLLQQRTWLI HWSLFVFFNHAKGRDTIIEMFLYEQSYLNAIQTMCPHILRYLTTAVVTNKQCMKDLVKII QHESYTYKDPITEFIECLYVHFDFDGAQKKLRDCETVLSNDFFLVACLDDFIENARLLIF ETFCRIHECISIGMLAEKLNMSPDDAEKWIVNLIRNARLDAKIDSKLGHVVMGTQAVSPY QQIIEKTKNLAFRSQVIAQNVEKKLGHSKMGVTIEELSPGDGRTFPKKGQLVVVHYTGTL DNGDVFDSSRDRGVPFKFHLGKGEVIKGWEEGIAKMSVGQRARLTCSPDYAYGNRGHPGV IPPKATLRFDVELL-----RYYCDYCDTYLTHDSPSVRKTHCNGRKHKENVRLFYQKWLE EQVQKIVDDTTAAFKAGKIQNNPFTPGGVMIPPPSGL----------------------- -----------------EPLTLERDVTRAVELLDVLQRSGEFPKLQALQKILQSEFLTAV REVYENVYETVDISGSPEIRANATAKATVAAFAASEGHAHPRVVELPKTEEGLGFNVMGG KEQNSPIYISRIIPDGVADRAKTLKRGDQLLSVDGVSVEGENHERAVELLKQSHGMVRLV VRYTPKVLEEMESRFDKQRAARRRQFLALVGTVLCDPKVYFNEEFYTDNWVESTKKGAEQ GKFVWSAGKFYGDADKDKGIQTSQDARFYGLSAKFDK-FSNEGKSLVVQFTVKHEQNIDC GGGYVKVFSSDLDQENMHGDSPYLIMFGPDICGPGTKKVHVIFNYKGKNLLIKKDIRCKD DVYTHLYTLVVNSDNTYVVKIDNEKVESGDLESDWDFLPPKKIKDPEAKKPEDWDDRENI DDPEDTKPEDYDKPEHIPDPEAKKPDDWDDEMDGEWEPPMIDNPEYKGEWKPKQIPNPKY KGKWVHPEIDNPEYSSDDSLYKYDDIGALGFDLWQVKSGTIFDNVLITDDEKYAEKYGTD TWGETKDPEKKMKEAQDEEESKKREEEEKKRKEEEDAKDEEEDKMDGGILEPSLYSIKAL AILDNDGNRLLAKYYDDTFPTAKEQKNLFNKTHRANAEIIMFEGLTCVYKSNVDLFFYVI GSTQENELILGSVLNAMYDSISQILRKNVEKRALLENLDAVYLAVDEICDGGIILEADSI AIVHKVAIRNDDIPLGEQTVAQVLQSAKEQIKWSLLKMNVFRLLGDMSHLLAILILLLKM WKTRSCAGISGKTQILFALVFTTRYLDLFSSFISIYNTTMKLFFIASSYFTIFLMYSKFK ATYDSNHDSFRMEFLVVPVGGLAFLVNHEFLPLEILWTFSIYLESVAILPQLFMVSKTGE AETITSHYLFALGSYRLLYIFNWVYRYYFDGFFDLIAVVAGCVQTILYCDFFYLYITKVL KGKKLSLPAMKIEEVKSTSKAQRIASHSHVKGLGLDENGYAIQTAAGLVGQESAREAAGI IVELIKSKKMAGRAVLLAGPPGTGKTAIALAIAQELGTKVPFCPMVGSEVYSSEIKKTEV LMENFRRAIGLRIKETKEVYDGEVTELTPVETENPMGGYGKTVSHVIIGLKTSKGTKQLK LDPSIYESLQKEKVEVGDVIYIEANSGAVKRQGRSDSFATEFDLEAEEYVPLPKGDVHKK KEVIQDVTLHDLDIANARPQGGQDIMSMMGQLMKPKKTEITDKLRKEINKVVNKYIDQGI AELVPGVLFIDEVHMLDIECFTYLHRALESTIAPIVIFATNRGKCTIKGTDDIVAPHGMP LDLLDRIMIIRTLPYRSEEMAQILRIRSQTESIQIDDDSLQMLANIGTKSTLRYAVQLLT PGNIMAHINGKECIGKDEVEEMNQLFFDAKSSAKHLAQHEDKYMKEFEVDEEGDQGLVKL KEKAKKRKGRGFPTKSGVEEYEGMDVDGPGPQRSVEGWILFITGVHEEAQEDDIYDKFTE YGEIKNLHLNLDRRTGFLKGYALVEYETFKEAQSAMDALNGSEILAQKINVDWAFVRGP- ---MSYQLYRNTTLGHTLQESLDELIRHGQISPNLALQVLLQFDKAINNALANRVKSKIS FKGKLNTYRFCDNVWTFVLNNVEFRTVDKVKIVACDGK-TFLFTSESVGEGHPDKICDQV SDAILDAHLKQDPNAKVACETVAKTGMILVCGEITSRAIVDYQKVIRNTIKQIGYDDSAK GFDYKTCNVLIALEEQSADIASGVHVDRNEEDIGAGDQGLMFGYATDETEECMPLTVVLS HQLNAKIAQLRRDGVLAWARPDSKTQVTVEYKYVKGAAIPLRVHTVVISLQHDETITTEK LRSELMDKVVKSVIPAKYLDNKTVYHIQPSGRFIIGGPQGDSGLTGRKIIVDTYGGWGAH GGGAFSGKDFSKVDRSAAYASRWVAKSLVKAGLCKRVLVQLSYAIGIAEPLSITVFSYGT SHKSEKELLEIIKNNFDLRPGKIVQELNLRSPIYQQTACYGHFGRPGFSWELPKKLKYMA GSALKRLMAEYKQLTLNPPEGIIAGPVNEENFFEWEALIMGPEGTCFEGGIFPARLTFPS DYPLSPPKMKFTCEIFHPNIYPDGRVCISILHAPGDDPMGYETSAERWSPVQSVEKILLS VVSMLAEPNDESAANVDAAKTWREDKTKFQEVAERTVRKSLGLMRLEKCYFCSSTIHPGH GIQFVRNDCKIFKFCRGKCHKAFKKRKNPRKARWTKAYRKATGKDLAVDPSFEFEKKRNI PIKYNRELWNNTIKAIDRIDKIKLKRQGQHIINRLKEGKKLRKEADVREVDKNIHLIRAP ----AEYTLVLVRHGESEWNKSNQFTGWYDCDLTEKGVAEAKFAGKALKEKGYTFDVAFT SVLKRAIKTLYFVQDELDLHWLPVHRHWRLNERHYGALQGLNKAETAEKYGNEQVHIWRR SYDTPPPALTPDDERWAGRDKRYADLDSSCVPACECLKDTVARVLPYWYDNIVPAIKSGK RVVISAHGNSLRALVKYLDNMTDDAILALNIPTGIPLVYKLDKDLKPLEHFYVADEEKVK AAMDKVANQGKAKMELQDIRYPHEEYIETASGNKVSRQSVLCGSQNIIINGKSIIMKDCM IRGDLANVRIGRNCVVR---------------VAFFPLHIGDNVFIGEDSVVNAAQVGSF VHIGKNCVIGRRSVLKDCCAIGDNTVLPPETVVPPFTYFSGSPGMSFLFGSRNNKTFKPK KNIPEGTHQYDLMKHAAVTLGSGNLRLAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTIT EFCSEETCPVMSAGPKYEYHWADGTTIKKPIKCSAPKYIDYLMTWVQDQLDDETIFPSKI GVPFPKNFLTIAKTILKRLFRVYAHIYHQHFKEVVQLSEEAHLNTSFKHFIFFVQEFSLI DRKELAPLQELIDKLSCKD-----------------------------QLYRFLARRTSA GFNKVVLRRLFMSRMHRPPIALSRLVKYATKPGREGRIAVVVGTITDDVRLMSCPKLTVC ALRVTERARARILKAGGEILTFDQLALRAPKGQNTVLVQGIRQARGANRHFGLAPGVPGS NTKPLVRAKGRKFEKARGKRNSRGYK-DMKLGNQQGSYSVANTVNLLVRIIAQTKWTSAL DLMNIVKSEGKRLMSSQPSETVIGNMVRRILKIIREEYVIEAVSELKSELETSAQALEHI HANEVIKTVEEFLKNKFQVIVVEYYGQELALSLAKSGIETMVINDTAVFAIMSRVNKVII GTHTVMANGGLKAIGSHAIALAAKHYSVPLIVCAAMFKLSPQYLCSYDDAFNKFVSPHEI HNPVFDYVPPELVTLFISNIGGNAPSYVYRLLSELYHMIIPIRCFTCGKVIGNKWEAYIG LLQVEYTEGDALDALGLKRYCCRRMLLSHVDLIEKLLNYAPLEKRSPEAVEGRKHIDVQT ELYLEELSDRVEEADVDCQTDAFLDRPPSPLFIPAKTGKDVATQILEGDLFDFDIEVKPI LEVLVGKTVEQALLEVMEEEELSNLRQQQRAFEELRNAELVEQQRLEEQERRHREEKERR MKQQHEVLKKEKETAEKIAARAFAQSYLADLVPSVFGTLADNGYFYDPVERDVEQGFMPW LMEQVEIQLEKSELGRMVLDGIIREVTSNRLDLY--MRVRGELKQYMVYGRHTPSATESN PPIFKMNIFANDKCSAKSRFWYHLRSLKKIKKAHGEILMCKLVGEKKPTVVKTYGVWLRY VSRSGIHNMYREYRELTAAKAVTSCYRDMGARHRARPSSIQIIRVKQVEDDKVRRPNIKQ FMKPNVRFPLPHRVNHKLYVPRFSTKRPQTKFSAYDEMKGYWDKNRQRPMSPLFAYKPHL AMLTSLSHRVTGVAMSVAITGTSCILLALPGDFTTYFDMVKDMSIPAAVIIGFKYLLAWP MTYHYINGFRHLAWDAGKGYDIKTLYKTGYFA-------TSSVQISTYRDQHFKGSRNDQ DHLLIQSTTLYVGNLSFYTTEEQIFELFSRSGDVKRVIMGLDKVRKTPCGFCFVEYYVRE DAENAVRYVNSTRLDDRIIRTDWDAGFREGRQYGRGKSGGQVRDEYRSDFDEGRGGYGKI VINKIKPNYTLKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGH KLGISDVAWSTDSRLLVSASDDKTLKIWDFSMGKCLKTLKGHSNYVFCCNFNPQSNLIVS GSFDESVRTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHKNEKYCIFANFSVTGG KWIVSGSEDNVVFIWNLQTKEIVQKLQGHTDVVLCCACHPTENIIASAALENDKTIKLWR SDVMYIFQEISSGDDLFTDAAKGLYYEVEATDDRLIGANPSSGLDVVLEDKSQFGKLIKS YFAKALEMEFFVSLTAFSWREAKMIFFKFGV------AVEFDGGVVIGADSRTTSGAYIA NRVTDKLTKVTDKIYCCRSGSAADTQAVADIVKYQLNFYEMEMGEEPLVHTAAHTFRELC YDHRDNISAGIIVAGWDKKEGGQVFAVPLGGMVVRQPFAIGGSGSTYLYGYVDSQFKPKM SKEECLPFVANALSLAINRDGSSGGIIRLAAITKDGVERITLTGNQLPKFILICAGALLF LVCCTYCMCKRCCRKKKKKEGKKGLKGAVDLKSVQLLGNAYKEKVQPDLDELQVNMEDNE DAESTKSEVKLGKLQFSLDYDFQKAELSVGVVQAADLPGMDMSGTSDPYVKVYLLPDKKK KYETKVHRKTLNPVFNETFTFKVPYAEIGAKTLVFAVYDFDRFSKHDQIGQVKIPLNSID LGKVTEEWQDLSSPDNEAEKENKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSD PYVKISMNLNGKRIKKKKTTIKKCTLNPYYNESFTFEVPFEQIQKVQLIITVVDYDRIGT SEPIGRVLLGCNSTGTELRHWSDMLANPRRPIAQWHTLQEVPEKNMVLADLGRKITSALK SLSNATIINEEVLNDMLKEICRALMEADVNIRLVKSLRENVRSVIDFDEMAGGLNKRRMI QSAVYKELVKLIDPGVKAFHPSKGKSNVIMFVGLQGSGKTTTCTKLAYYYQKKGWKTCLI CADTFRAGAFDQLKQNATKARIPFYGVDTSGRHKQEDSLFEEMLQVHQATPDNVVFVMDA SIGQACEAQARAFKDKVDVASVIITKLDSHAKGGGALSAVTKSPVIFIGTGEHIDDFEPF KVQPFVSKLLGMGDIEGLIDKVNELKLDDEELMKKLKQ---------------GQFTLRD MYEQFQNIMMSILAYNGAAIIAMNGKDCVAIAADRRFGVQAQTVSMDFDKIFEMGPHLYI GLPGLATDVQTVSQRLNFRLKMYELRENRRIRPKTFMSMVSNLLYERRFGPYFVEPVVAG LDPKTHQPFIASMDLIGCPMITDDFVVSGTCSEQMYGMCESLWEPNLEPDDLFETISQAL MNAFDRDAVSGWGAVVYIIEKDKVTKKLLKTRMDMTSKDYYFDSYAHFGIHEEMLKDEVR TLTYRNSMYYNKHLFKDKIVLDVGCGTGILSMFAAKAGAKKVIGIECSSIIDYAQKIIVD NRLDKVITLVKGKVEEVVLPDGIEKVDIIISEWMGYCLFYESMLNTVIFARDKWLAKDGL IFPDRATLYICGIEDRQYKDEKINWWDNVYGFDMSIIRGVAINEPLVDVVDHKQVVTNSC LVKEVDIYTVKIEDMVFTQPFHLQCRRSDYLHALVTFFNIEFTKCHKRTGFSTAPEAPYT HWKQTDNDLTIKKGEELNGTFSMKPNKQNNRDLDFQLELDFKGELSEMSESLRYKMRMVK EDKQTWKSKYFMRLVQLFDEYPKCFIVNADNVGSKQMQSIRIALRVLMGKNTMMRKAIRG HLENNSTLEKILPKIRGNIGFVFTKDDLVEVRAILLESKVKAPAKAGALAPLDVKVPAQQ TALGPEKTSFFQALQIPTKITKGTIEILNEVNLIKEGEKVGASEATLLNMLNISPFSYGL VIENVYDSGTIFSPKILDITDNYLKGVFMEGVRNIASISLVVGYPTAASVPHSIANGFKN LLALACVTEISFTEAEKTKESAQKGRLIAVIGDEDTCTGFVLGGIGEIDKNRRPNFLVVD KNTSVPEIEDVFKSFVSRDDIAIILINQSFAEMIRHAIDKHTEPIPAVLEIPSKEAPYDA SKDSILRRAKGMFSAEDFRGNENSLPLELCSTFDADEIKRLGKRFRKLDLDNSGSLSVEE FMTLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGISQFSVKGDKESKLRFAFKIYDMD KDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIIHADTDGDGKISFEEFCSVVGTMDV HKKMVVDVMTYIKSWDEFAKAVERVYVNNPLKCRFVMKYRNVDGLLTMKITDDHVCLQYK TEHNQDVKKLEKLLGHLIRDMASKELYEEVKLYRTARDREKYDNMADLYAVINTIQSLEK AYIRDAVLPKEYTAACSKLLVQYKAAFRQVQS-EFTTVEEFMKKYRLDCPAALERIKELR PITIKDDKGNTSKCIADIVSLFITVMDKLRLEIKAMDEIYPDIRELEETMNRLSILPSNF EGKETVKKWLDTLSSMTASDELDNNQVRQMLFELESSYNAFNRVLHDMLSNLVKQHQMRQ TARKEIQEKRKKDAIVSTALSHVLVDHLNSGVAQAYVNQKKLDTETKILQANASQFSKQT IQWLKLIEDFNTALKEIGDVENWARSIETDMRTISSALEYAYRAKGETKKVGGEKNGSER IVPAQKKPRYYPTETRPKKLVSSFNGHAHKLRPSITPGTVLIVLAGKHKGKRVVYLKQLR SGLLLVTGPFTVNGCPLRRVNQIYVIATKTKLNIDNIKLPERLNDDYFKKKKTRKAPKNE GDLFESTKEAKTVSPELKEDQVNVDKQVLEAISKHPDHKLFTGYLKSIFWLKKSQFPHNM IFLEWLFGRKKTPEEMLRQNQRALNKAMRDLDRERQKMEQQEKKVIADIRTMAKKGQMDA VKVMAKDLVRTRRYVKKFIAMRANIQAVSLKIQTLKSSNTMAQAMKGVTKAMQTMNKQLK LPQIQKIMMEFEKQSEIMDMKEEMMSDAIDDAMGDEDDEEESDAVVSQIFDELGLQMADD LNNLPQTGKSPAKQAVPVSDADADLEARLENLRRQNNYCDFCLGDQGENKKTNQAEDLVS CSDCGRSGHPSCLQFTDNMIVSVKKYPWQCIECKSCGLCGTSDNDDQLLFCDDCDRGYHM YCLNPPLQEPPEGNWSCHLCIEEFHGTIERTINLYPLTNYTFGTKEPLYEKDSSVPARFQ RMRDDFEKIGMRRSVEGVLIVHEHSLPHVLLLQLGTTFFKLPGGELNPGEDEVEGLKRLL TETLGRQDGGPMEWVVEDTIGNWWRPNFEPPQYPYTPAHITKPKEHKRLFLVQLPEKALF AVPRNYKLVAAPLFELYDNSAGYGPIISSLPQTLSRFNFLYNMTPGGMTPTMTPAMAMAT PTPGHLMSMTPEQMQAYSWQREIDERNRPLPDDELDAMLPPGYKVIQPPAGYIPIRTPAR KLIATPTPMAGTPVGFRMQTQIVDMQPKGNLPMMKPDDMQYFDRKIMKLLLKIKNGTPPM RKAALRVVTEKAREFGAGPLFNQILPLLMSPSLEDQERHLLVKVIDRILYKLDDLVRPYV HKILVVIEPLLIDEDYFARVEGREIISNLAKAAGLATMISTMRPDIDNMDEYVRNTTARA FAVVASALGIPALLPFLKAVCKSKKSWQARHTGIKIVQQIAILMGCAILPHLKNLVEIIE HGLVDEQQKVRTITALALAALAEAATPYGIESFDSVLKPLWKGIRQHRGKGLAAFLKAIG YLIPLMDAEYANYYTREVMLILIREFQSPDEEMKKIVLKVVKQCCATDGVEPQYIKDEIL PPFFKHFWNQRMALDRRNYRQLVDTTVEIANKVGAAEITGRVVDDLKDEAEQYRKMVMET IEKIMGNLGATDIDSRLEEQLIDGILYAFQEQTTEDVVMLNGFGTVVNALGKRVKPYLPQ ICGTILWRLNNKSAKVRQQAADLISRIAVVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLG SILGALKGIVNVIGMTKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGAEFVS AREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVC TTVAIAIVAETCSPFTVLPALMNEYRVPELNVQNGVLKSLSFMFEYIGEMGKDYIYAVTP LLEDALMDRDLVHRQTGMAAIQHMALGVYGFGCEDALTHLLNYVWPNVFETSPHVVQAFM GAVEGIRVAIGPSKILQYVLQGLFHPARKVRDVYWKVYNTVYIGAQDGMIPAYPRIPNDA KNQYLRYELDYILEEFMCEDEEYDLEYSEESNSEPDVDLENQYYNSKALKDDDPKAALES FQKVLELEAKEKGEWGFKALKQMIKINFKLNNYEEMMIRYKQLLLYIKSAVTRNYSEKSI NSILDYISTSKQMELLQNFYETTLDALKEAKNERLWFKTNTKLGKLYYDREDFTKLQKIL KQLHQSCQTDEGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPL IMGVIRECGGKMHLREGEYEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGIN PFDSQETKPYKNDPEILAMTNLVSAYQNDDINEFEKILKTNRRNIMEDPFIREHIEDLLR NIRTQVLIKLIKPYTRIHIPFISKELNIDAIEVENLLVSCILDSTINGRIDQVNQVLKLS TGIGRYDALDKWATQLHNLHHAVISKMAVLLMGKSGSGKTSMRSIIFANYIARDTRRLGA TIDVEHSHVRFLGNLVLNLWDCGGQEAFMENYFASQRDNIFRNVEVLIYVFDVESRELEK DMHYYQSCLEAILENSPDAKVFSLIHKMDLVQDDQRERIFKEREEDLKRLSKPLATSIWD ETLYKAWSSIVYQLIPNVQKLESNLTAFGDTIDADEVLLFERATFLVISHCERRPHEDVH RFEKISNIIKQFKLSCSKLAASFHCMEVRNSAFTAFVDVFTSNTFVMVIMSDKTIPSAAT LLNIKNAKKYFENLDKVD-ILAFSTRLFSVLQFESVIHEFDPYFNYRTTKFLAEKGFYNF HNWFDDRAWYPLGRIIGGTIYPGLMVTSAMIYNFLNFLHITIDVRNVCVFLAPLFASFTT IVTYMFTKELKDAGAGLVAASMLAIVPGYISRSVAGSYDNEGIAIFCMLLTYTLWVKAAK TGSVFWASLCALAYFYMVSSWGGYVFLINLIPLHVLVLMITGRFSHRIYVAYSSVYCLGT ILSMQIAFVGFQPVQSSEHMAALGVFGLCQIHAFVDYLRSKLTTEQFNLLFKSLVLLSGS IIATALGKISPWTGRFYSLLDPSYAKNNIPIIASVSEHQPTAWSSFYFDLQLLVFMFPVG LYYCFSKLTDANIFIIMYGVTSIYFSGVMVRLMLVLAPVMCILSGIGVSAVLSTYMKNLD VAKKTDNTYPLKNEIATGVIMIMTSFLIMYTFHCTWVTSEAYSSPSIVLTARGGDNGRII FDDFREAYYWLRQNTHHDAKIMSWWDYGYQITAIANRTVLVDNNTWNNTHISRVGQAMAS PEDKAYEIMRELDVDYVLVIFGGLTGYSSDDINKFLWMVRIGGSTDRGAHIKESDYFTPQ GEFRVDKDGSPILLNCLMYKMCYYRFGSVYTEGGKPTGYDRVRNTEIGNKDFELEVLEEA YTTEHWLVRIYKVKDLENRG-KLNIKPLLRLVCSRFFGSFTGFVDMCIEHVPSPQDNGKS KIEHLYTGPSDSELAEEMFNCDPEGPLMIHTTKLYPTNDATCFHVFGRVMSGTLHANQEV RILGENYTLQDEEDSRFGQVGRLWIAEARYKIEVNRVSAGNWILIEGIDQPIVKTSTITD VSTNDEVYIFRPLKFNTSSVIKIAVEPVNPSELPKMLDGLRKVNKSYPLLTTKVEESGEH IVLGTGELYLDCVMHDLRKVYSEIDIKVADPVVSFCETVVETSSLKCFAETPNKKNKLTM IAEPLEKGLAEDIENEVVQITWPRKKLGEFFQTKYDWDLLAARSIWAFGPDATGPNILVD DTLPSEVDKTLLSAVKDSIVQGFQWATREGPLCDEPIRNVKFKILDAMIAGEPIHRGGGQ IIPTARRVAYSAFLMATPRMMEPYYFVEVMAPADCVSAVYTVLAKRRGHVTQDAPVPGSP LYTIKAFIPAIDSFGFETDLRTHTQGQAFCLSVFHHWQIVPGDPLDKSIIIRPLEAQPAT HLAREFMIKSRRRKGLSEDVSINKFFDNPMLLELARQDVLLNYPM-ETFSLFDEKGDHKI AVQQLGDVLRALGQNPTEAEIRKCNNQDARISFEMFLPILQTICKNRQVPSFDDFIEGFK VFDKEQNGLMSSAELRHILTSLGDKLNDDEVDQLFAGLEDAQGNINYEELIKTVM--MPE LSFNIDHGYLEGLVRGFKCGVLKQADYLNLVQCETLEDLKLHLQSTDYGNFLANEPSPLT VSVIDDKMREKLVVEFQHLRNHCLEPLATFLDYITYSYMIDNIILLITGTLHQRPINELI SKCHPLGSFEQMEAIHIASTPAELYNAVLVDTPLAPYFIDCISEQDLDEMNIEIIRNTLY KAYLEDFYNFCKNLGGATAEVMCEALAFEADRRAFIITINSFGTELSKEDREKLYPRCGN LYPDGLSKLSQAEDYDQVRQVAEYYASYRELFEGAGTNPGDKTLEDKFFEHEVKLMKQSF MHQFQFGVFYSYVKLKEQECRNIIWIGECVAQRHRAKIDSYIPIFSPRKAVRKISKIPFK VLDAPELQDDFYLNLVDWSSQNVLSVGLGTSVYLWSACTSQVTRLCDLMTDGDTVTSVSW SDRGNQVAVGTNKGHVQIWDVAMTKKINTLEGHSARVGALAWNGDMLSSGSRDRLILQRD IRTPMIAPERRLTGHRQEVCGLKWSPDHQHLASGGNDNKLYVWNMTNTTPVQTYTEHLAA VKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCVDTGSQVCNLAWSKHSNEVVST HGYSQNQILVWKYPSLVQISTLTGHTYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTK STKESKSVLNLFTRIRVLIIVGLYYNLTGRGSRFDIGWFLQSTSPYMWALIGVGFAISLS VVGAAWGIYTTGTSISGGGVKAPRIKTKNLISIIFCEAVAIYGIIMAIVISTNQNYGAGF MMFGAGLTVGLTNLACGICVGIVGSGAALADAANGSLFVKILIIEIFGSAIGLFGLIVAI LQTSNAVM---MAATRRLQKELNDRVDDSNILFWQGLIVPDVPPYNKGAFKIEISFPAEY PFKPPKLAFKTKIYHPNVDEKGQICLPIISPENWKPATKTDQVIQALLALIHDPEPEHPL RGDLAEEFTKDKKKFMKNAEDFTKKFSERRPSDGASDTYPKQCSALRKNEHCLIKGRPVK IVEMTTSKTGKHGHAKVHLTGIDIFNGKKYEDICPSTHNMNVPNIKKAEYQLVDIGRNFL SLLSDHGIIRSDLRLPVTVIEAMGEEVVNSLK---GQFNYPWDVAIGSDGRMIVSDTRNH RVQLFNSEGQFMNKYGFEGWKHFDSPRGVAFNNEGHIVVTDFNNHRLLVIHDFQSARFLG TEGSGNGQFLRPQGVTVDQEGNIIVADSRNHRIQVFQPNGNFLCKFGMDRPSGLCVNPDG LLIVIDFGNNRIQVY---MSSAPIAERNQDATVYVGGLDDKVTEAILWELFLQAGPVVNV HMPKDRVTQTHQGYGFIEFLGEEDADYAIKIMNMIKLYGKPIRVNKASAHQKNLDIGANI FIGNLDPEVDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGFAFINFASFEASDAAIEAM NGQYLCNRPISISYAFKKDSKGERHGTAAERLLASQNPLSLTDRPHQLFADAPPPPSQPN MAPPPPPPGMG-------NMPPGSMMPPPMPP----MPPGMHPDPPPPGWRPPPPGMRGM RPQPPRGNRPPPPNMRPPP-KVDAKKLSNPLFIKRRKDFRIGQDIQPKRDLTRFVRWPKY VQLQRQRVVLYKRIRIPPPINQFTQTLDRQTAQQLFRLMDKYRPETALAKKRRLKKRAEE KVAKGTDAPTKRPVTVRSGVNTVTRMVESKKAQLVVIAHDVDPIELVLFLPALCRKMNVP YCIVLGRVVHRKTSTCLAIPTVNSEDKSSLSKLVEAVRTNYNERHEEIRRTWGGGILSKR SQAKQARIERIKAKELAQRMRYVAAYLLATLGGQTKPTAADIEKILSSVGIESEADKVKT VIGELSGKNLEDLIAEGQKKLATVPSGGGAAPGDAKKAAESDEDMGFGLFDMPIKSIKAR QIFDSRGNPTVEVDLYTENGLFRAAVPSGASTGIYEAIELRDKDPKAYHGKGVSKAVDNV NSRIAPLLLPDITNQTAVDQMMIDLDGSDNKGTLGANAVLGVSLAICKAAAKQKGVPLYK HIADLAGNPKVILPVPSFNVINGGSHAGNKLAMQEFMILPLGAKSFTEAMRMGTETYHHL KAVIKKKYGQDACNVGDEGGFAPSIEDNREGLELIKIAIEKAGYTGKIKIGMDTAASEFC KLYDLDFKNPASDKASWLSPDQLADLYRTFIKEYPIVSIEDPFDQDDWEGYTKFTAIQIM GDDLLVTNPTRVQKGIDLKACNSLLLKVNQIGTVTEAIKACKMAQGAGWSVMVSHRSGET EDSFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGADAVYAGEKFRNP----- -----------TNFRLFYNRGDFPIALEHDTKGNKIAWKVEIEKLDYHHYLPLFFDGLCE TVHPYEFFARQGVHDMLEHGGSKILPVIPQLIIPIKNALNKRNHKVLCTTLKVLQHLVVS ADLVGEALVPYYRQILPVMNIFKNKNLNSGDGIDYSQQKRENVGDLIQETLEAFERHGGE DAFINIKYMVPTYESCMMNAPPTFEAFLLFEGEKKITIEKDTKVPNAALFTVNKEDHTLG NMITTQLLKDPQVLFAGYKNPHPLEHKFVVRIQTTSDYSPQEAFTNAITDLISEISLLEE RFKESVKERAE---DHRKKWDLDEYEKLAKERLEEELSDKEIPVKRELLQPRDYKVDLDS KLGKSQVITKTTPAFQQGGYFCNVCDCVVKDSINFLDHINGKKHQRNLGMSMKIERSSLD QVKKRFEMNKKKKEEKSKEYDFEERMKELKEEEEKQKAYKKEKRKERKRKADTDEGDQDM AALMGFSGFGGSKKMGCTLSAEERDAMERSKAIERNLKEDGIQAAKDIKLLLLGAGESGK STIVKQMKIIHEGGFTSEDNKQFKPVVYSNTIQSLVAIIRAMSTLNINFGDNDRESDAKM VLDVIARMEDTEPFSEELLAAMKRLWNDSGVQECFGRSNEYQLNDSAKYFLDDLERLGAK DYMPTEQDILRTRVKTTGIVEVHFSFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCV AMSEYDQVLHEDETTNRMQESLKLFDSICNNKWFTDTSEEKIKKSPLTICFGEYTGKQTY EEAAAYIQAQFEAKNKSSTKEIYCHQTCATDTNNIQFVFDAVTDVIIANNLRGCGLYYHS SL-PCPRLVGNMGLLPIKTQYKGPASDIIDEAIGFFKANIFFRNYEIKSEADRTLIYVTL YITECLKKLQRCSSRSQAEKEMYTLGITNFPIPGEGGFPLNAMYSKPS-RQEDETMRAYL QQLRQETGLRMIDRVFDQQSDKPSKWWLCFAKRKFMDKSLSPAG-AGPYNYSYIFKYIII GDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVAGQKIKLQIWDTAGQERFRAVT RSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIFLIGNKCDLDAQRDVTFE EAKQFAEENGLMFLECSAKTGENVEDAFLDTAKKIYQNIQDGSLDLNAAESGVQHKPATP RNPLNTDTPPNKEGCAC----AVCVLKDGVGEGVVHFTQQGPVVVKGKLEKLQPGEHGFH IHELGDNTNGCISAGGHYNPFSKTHGGPTSDDRHVGDLGNVTANEFTITDKQLKLTGPYS IIGRTVVVHEKVDDLGKGGNDESLKTGNAGPRLACGVIGITKMVNFTVDEIREIMDKKLN IRNMSVIAHVDHGKSTLTDSLVSKAGIIAGSKAGETRFTDTRKDEQERCITIKSTAISLF YNLNEDDKDCGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQA IAERIKPVVLMNKMDLALLTLQLDKDTLYHTFQKIIEDVNVIVNTYGESDGPMGDIEVDP RNGTVGFGSGLHGWAFTLKDFAKIYAAKLKIEPAKLIKKMWGNQFYNNVRGFIFFVLNPI YQIFDACMTNEDALALVEKLNIKLTADDKQLVEKPLLKTIMRKWLPAGDAMLQMIVIHLP SPVTAQKYRCEMLYEGPIDDDAAMSMKNCDPEGELLMYISKMVPTNDKGRFYAFGRVFGG TVSTGQKVKIMGPNYDPEKSIQRTVLMMGRYVEAIEDVPCGNICGLVGVDSYIVKTGTIS TFSKAHNMKVMKFSVSPVVRVAVDCKNPSDLPKLVEGLKRLAKSDPMVQCSTEESGEHII AGAGELHLEICLKDLEEDHACIPLKKSDPVVSYRETVSEESSQTCLSKSANKHNRLFVKA APLPEGLAQAIDDGDITPRQEFKSRAKVLAEEYNMDVGEARKIWAFGPEGTGPNFLMDCT KAVQYLNEIKDSCVAGFNWATKEGVMCEENMRSVRFNIQDVTLHTDAIHRGGGQIIPTAR RVFYASFLTAAPKILEPVYLVEIMVPDAAMGGVFSTLNRRRGVVFENNPVGNTPQTLVKA HLPVNESFGFTGDLRSQTQGKAFPQCVFDHWQILVVSSARKRKGLKEGVPLLENFLDKMM LPLSLLRTAVNHPMLVELKNGETYNGHLVSCDNWMNINLREVICTSRDGDRFWRMPECYV RGSTIKYLRIPDEVIDMVKEDVMQKSKGRGEVR---RGGRGRGKENKR------------ ---SEFKLKNPPSDGISAIKFGPTSSQFLLVSSWDTTVRLYDIISNNQRMIYSHTDPVLD CCFQDSVHSFSGGIDKTLKMYDFNTQTETVVGTHDRAVKCVEFGADVNVIVTGSWDSTVK LWDPRSPCCAGSFTQPDKVYTLSIAGDKLIVGTAGRRVLVWDLRNMGYVQQRKESSLKYQ TRCIRCFPNKQGYVLSSVEGRVAVEYFDQSPEVQKKKYAFKCHRVKENGVESIYPVNAIA FHSQYNTFATGGSDGYVNIWDGFNKKRLCQFHKYPTSIASLAFSNDGSVLAIASSYMFEK GTPEDEIFIRNVSDQETKPKMDFQHRAGGKTGSGGVASASETNRDRRERLRQLALETIDL NKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQANLARRAAKEAKEAPSQPAPE KAKVEIKKFVKIGRPGYKVTKQRDPDNGQQSLLFQIDYPEIVDVIMPRYRFMAAYEQKIE PPDRKWQYLLFAAEPYETIAFKVPSREVDKDPKKLWTHWNRDTKQFFLQFAFKYDPNRLP PPPPPMGPPGMR--DEQETYKLWRIRKTVMQLCHDRGYLVTQDELDQTLDEFKAQFGDKP SERKPGRSDLIVLVAHNDDPTDQMFVFFPDEPRVGIKTLRPYIKRMEEENITRAVIVVQV GMTPSSKQALVELSDKYTLEQFIEAELLVNITEHMLVPEHVVMTPEEKAELLVRYKLKEA MIPRIQQGDPVARYFGLKRGQVVKIIRPSETAGRYVSYRLVVKDKDAVGTVIGIDLGTTY SCVGVFKNGRVEIIANDQGNRITPSYVAFTEEGERLIGDAAKNQLTSNPENTIFDVKRLI GRNWDDASVQHDIKYYPFKVIQKNSKPHIKANVQGTDTVFAPEEISAMVLGKMKEIAEAY LGKSITNAVVTVPAYFNDAQRQATKDAGKIAGLNVMRIINEPTAAAIAYGLDKKEGEKNI LVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRK DNRAVQKLRREVEKAKRTLSSQHQARIEIESLFEGEEFSETLTRAKFEELNMDLFRSTMK PVQRVMEDSDLKKDEIDEIVLVGGSTRIPKIQQLVKEYFGGKEPNRGVNPDEAVAYGAAV QAGVLSGEEDTGDLVLLDVNPLTLGIETVGGVMTKLISRNTVIPTKKSQIFSTASDNQPT VTISVLEGERPMVKDNHLLGKFDLTEIPAAPRGVPQIEVTFEIDVNGILRVSAEDKGTGK KNEIVIKNDQNRLSPEDIERMINDAEKYSEDDKKVKEKVEARNELESYAYSLKNQVNDKE KLGAKLSTEDVAKINEALEEKIKWMESNQDAEIEEYKEQKKELEAVVNPITSKLYEGAPP PEGGEDHDEL-------ELEAIKARVKEMEEEAEKLKEMQSEVEKQMTIEEKVDADSKSV YVGNVDYAATAEELEQHFHGCGSINRVTILCDKFTGHPKGFAYVEFADKDSITTAMALDD SLFRGRQIKVSPKRTNRPGISSTNRPPR----RARG------------------------ ----VMSESMSELIHNRTFQSLIEAVKLEKAKKAALQNTIQKEEDGRKRVRQLQKQLLDV KKEKESELQNREEMIAHLKDQLQEMKAKTNMEGKYIKKCAEVGVTQTQKRCYLSEKEMKD EIDNLQNQIDKETRANAEIESFLRNHHANLEKKLDFWQEKYEKDVESKQHELDVLKASKA KDLERLQELTKLYKEYEQVVVEDRIEKEKVRRKDELEAIELRGAIKVQAWWRGLMVRKGF GPYGKKKKGKIKIGINGFGRIGRLVMRAAIEKLEIVAVNDPFIDLDYMVYMFKYDSTHGR FKGEVKLIINGKPTIVHMLRDPTEIPWGAAGAEYVVESTGVFTTLEKAGAHFKGGAKKVV ISAPSSDAPMFVMGVNEDKYEKSMNVVSNASCTTNCLAPLVKVVNDNFGVEEGLMTTCHA FTATQKIVDGPSMKDWRGGRGAAQNIIPSSTGAAKAVGKVIPELNGKLTGMAFRVPVADV SVVDLTVRLKKPASYDAIKEAIKGPMAGVLGYTEDAVVSADFISDTRSSIFDAKAGIALN DNFVKLVSWYDNEYGYSNRVIELI--------DDLATAILRRKEKPNRLLVEEAINDDNS VVSLSQKKMDELQLFRGDTVLLKGKRRRETVCIVLSDDTVTDDKIRVNRCVRNNLRVRLG DVVSIQACPDVKYGKRVHVLPIDDTVEGLTGNLFEVYLKPYFLEAYRPVRKGDIFLIRGG MRAVEFKVIETDPAPYCIVAPDTVIHCEGEPVKREEEEEALNEVGYDDIGGCRKQLAQIK EMVELPLRHPQLFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSK LAGESESNLRKAFEEAEKNSPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQ RAHVIVMAATNRPNSIDAALRRFGRFDREVDIGIPDATGRLEILRIHTKNMKLSEGVDLE QIGQETHGHVGADLAALCSEAALQQIREKMDLIDLEDEHIDAEVLDSLAVTMDNFRWALS KSNPSALRETSVEVPNVSWEDIGGLENVKKELQELVQYPVEHPEKFLKFGMTPSKGVLFY GPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARSAAPCVLFFD ELDSIAKSRGGNAGDGGGAADRVINQLLTEMDGMSAKKNVFIIGATNRPDIIDPAILRPG RLDQLIYIPLPDDKSRIAILKANLRKSPVAKDVDVDYLAKVTHGFSGADLTEICQRACKL AIRQSIEAEIRFEKQRAQDPEESDPVPEISRAHFEESMKFARRSVSDNDIRKYEMFAQTL QQSRGFGGGGTSSFGTPTVFGQSTNLNPMKDFEVTSPPDDSVSCLKFSPGTLPSTFLIAG SWDNNVRCWEIQQNGQTVPKAQQSHTGPVLGVDWSDDGTKVFTASCDKTAKMWDLSSNQF MQVAVHDAPIKTVHWIKAQNYSCLMTGSWDKTLKFWDTRSPNPILSIQLPEKVYCADVKY PMAVVGTSNRGIIIYQLENQPREFKRVESQLKYQSRCISIFMDKKTNTPTGFALGSIEGR AGIQYVNPTNPKDNFTFKCHRGSMQDIYAVNDIAFHPVHGTLATVGSDGRFSFWDKDART KLKSSELFDQPITCCNFNAQGNIFAYATSYDWSKGHEGYDPQKMKPHIFLRSCFEEFKPS TKRMSSPSPGKRRTDTDILKLIESRHEVTILSGLNEFSVKFYGPVGTPYEGGVWKVRVDL PEKYPFKSPSIGFMNRIYHPNIDEVSGTVCLDVINQAWTALYDLLNIFESFLPQLLTYPN PIDPLNGDAAALYLHKPEEYKKKVKEYVQKYATSAALREQESSMSDFSEDEAQDMELMDE REVITTLKILIIGESGVGKSSLLLRFTDDTFDPEQAATIGVDFKVKTLAVDGNKAKLAIW DTAGQERFRTLTPSYYRGAQGVILVYDVCSKQSFSKLDAWLNELETFSTKHDMVKMLVGN KIDKEKREVSKDEGLKFARKHHMLFIEASAKTKEGVQCAFEELVEKIIQTPGLWETDGIT VGSVIWSIINNSFCSHKIKTKTQTFCRNEYNLTGLCSRRACPLANSQYATVREEKGICYL YMKTVERAAFPSRMWEKVKLSRNYEKALKQISDELIYWPRYIIHKCKQRFTKITQYLNRI RRLTLKRQKKIVPLNRKIERRETRREEKALVAADLSNNIEKELLERLKKGTYGDIYNFPS HAFDNVMKEEEVEEEEEGEREVEYVAEEDFEESDVSDME------QTQPRMKKFQIYRFD PDSPGAKPSMQTYEIDLNHCGPMVLDALIKIKTDDDPTLTFRRSCREGICGSCSMNINGT NTLACINKIDSNTSKVTKIYPLPHMYVVKDLVPDMSNFYAQYRSIEPFLKKKDTGESDIG KTQYLQSTSDRAKLDGLYECILCACCSTACPSYWWNSDKYLGPAVLMQAYRWMIDSRDDF TDERLSKMEDKFSVYRCHTIMNCTKTCPKGLNPGRAIGEIKKMMLDY-----------PN HTIYINNLNEKIKKDELKKSLYAIFSQFGQILDIVALKTLKMRGQAFVIFKEINSAANAL RSMQGFPFYDKPMRISFSKKDSNVIAKMKGTYVEEPRRKRDD-RKKKTKSQTSTAIPEQP PNQILFITNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFETEVQAGVAKDALQ GFKITPSNAMKISYAKKMDSQGRSVVVCDNGTGFVKCGYAGSNFPTFLFPSLVGRPIIRS QTKIFDIEVKDLMVGEEASKLRSMLEVNYPMENGIVRNWDDMLHLYDHTFGKDMMNINPQ NTRILLTEPPMNPMKNRERMIQTMFEKYQFHSVHIAIQAVLTLYAQGLLTGVVVDSGDGV THICPVYEGFALPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMMKERLCYV AYDVEQEQKLALETTVLVEPYTLPDGRVIKVGGERFEAPEALFQPHLINVEGLGVAELLF QTIQSADIDLRPELYKHIVLSGGSSMYPGLPSRLEREMKQLYLEKILKGNAEKLSKFKIK IEDPPRRKHMVFLGGSVLSDIMKDRDEFWMTRQEYEEQGIRVLDKL---MSDTVGKTITC KAAVAWEAKKPLVTETIEVEPPRAGEVRIKILATGVCHTDAYTLDGFDSEGAFPVVLGHE GGGIVESVGEGVTSVKTGDHVIPLYIPQCYDCKFCTSKKTNLCSKIRATQGKGVMPDGTS RFRCNGKQLFHFMGCSTFSEYTVVAEISVSKVDEKAPLEKVCLLGCGISTGYGAALNSAG VESGSTCAVWGLGAVGLAVIMGCKKAGATRIIGVDINSAKFKVAEDFGCTEFINPKDYDK PIQEVIVEKTDGGCDYTFECIGNIGTMRAALESCHKGWGVSTIIGVAGAGQEISTKPFQL VTGRVWKGSAFGGWKSRDSVPKLVDEYMRKELKVDEFVSFTLPLDKINEAFDYMHSGKSM ESYDVIANQPVVIDNGSGVIKAGFAGDQVPKYIFPNYIGRPKHVRVMAGALEGDTFLGPE AEEHRGLLSIRYPMEHGIVKDWNDMERIWQYIYSKDQLQTFSEEHPVLLTEAPLNPKRNR EKAAEIFFETFNVPALFISLQAVLSLYATGRTTGVVLDAGDGVTHAVPIYEGFAMPHSIM RVDIAGRDVSRYLRLLLRKEGFDFHTTAEFEVVKTIKEKMCYLALNPLKEESIDTDKAQY SLPDGNTILVGPARFQAPELLFRPDLIGEECQGIHEVLAYSIQKSDMDLRRTLFSNIVLS GGSTLFKGFGDRLLSEVKKLAPKDIKIRISAPQERLYSTWIGGSILASLDTFKKMWISKR EYNEEGVKALHRKTFDPSKIQKVVVHPLVLLSVVDHFNRMGKVGNMKRVVGCLLGSNRAG ILDVSNSFAVPFDEDERDKKVWFLDHDYLECMYGMFKKVNAKEKIVGWYHTGPKLHPNDI TINEMMRRYCPNSILVVIDAKPKDLGLPTEAYIAVEEVHDDGTPTSKTFEHVPSDIGAEE AEEVGVEHLLRDIKDTTVGTLSQRITNQLMGLKGLHGHIKDISSYLNKISTGQLPINHQI IYHLQDVFNLLPDVNLQDFVKAMYVKTNDQMLVVYIASLIRSIIALHNLINNKIQNRDAE KNEFKDPKMGYLFSKLWSLFTNEEHKVIIVGLDNAGKTTILYQFLMNEVVHTSPTIGSNV EEVTWNNIHFLMWDIGGQESLRAAWNTYYTNTEFVIVVIDSTDRERLSLTKEELCKMLAH EDLKKAAVLVFANKQDIKGCMSPAEISQQLSLTSVKDHVWHIQACCALTGKGLYKGLEWI TSHLKR-----RRVILHDAAHMPNDYSSTPGGTIFSTTPGGTRIVYDRAFLLQCRNSPLT KSPPPNMAKIPGVTTP-PPGKRKEIYKYEAPWTVYSMNWSVRPDKRFRLALGSFVEEYNN KVQIVALDEETSDFVAKSTFDHPYPTTKIMWIPDSKGVFPDLLATSGDYLRVWRVTRLEC LLNNNKNSDFCAPLTSFDWNEVDPNLLGTSSIDTTCTIWGLETGQVIGMVSGHVKTQLIA HDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHIPLLRLAWNKQ DPNYLCTMAMEAQECIILDVRVPCTPVARLNNHRACINAITWAPHSSCHICTAADDHQAL IWDIQQMPRAIEDPILAYTAAGEINQIQWSSTQPDWISICYNNNMEILRVRSFSTHAKVC VLGASGGIGQPLSLLLKNSPLISRLSLYDIAHTPGVAADLSHIETRAKVEGFMGPDQLEK CLQGSDVVLIPAGVPRKPGMTRDDLFNTNAGIVRDLADACSRVCPKAMLGIITNPVNSTV PIAFEMYKRNGIKEQKRIFGVTTLDTVRSNTFVAEAKGLDVSKVNVPVIGGHSGITIIPV MSQANPPVSFPSDERAKLTVRIQNAGTEVVEAKAGAGSATLSMAYAAAQFCFSLLEAMAG VDGKIECAYVRSSLTDASYFATPIALGKEGISQNLGLGKLNDYETELLKAAIPELKDNIK KGEDFVNK-IDRGKDFNIKTRIITDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFAS TLSHLRRLNSPIGRDGKLARPRQLHNTLWGMICPAETPEGAAVGLVKNLALMAYISVGSQ PSPILEFLEEWSMENLEEVAPSAIQDASKIFVNGCWVGIHRDPDQLMSTLRKLRREMDII VSEVCMIRDFHEREIRIYTDAGRICRPLLIVENMKLLLKKSHIKQLKLREYNNYSWQDLV ASGVVEYIDPLEEETTMLAMTPDDLAEKEAQYCSTYTHCEIHPAMILGVCASIIPFPDHN QSPRNTYQSAMGKQAMGFYITNYHVRMDTLAHGLFYPQKPLVTTRSMEYLRFRELPAGIN SIVAIACYSGYNQEDSVILNSSAIDRGYFRSFFFRSYKDSESKKGLDQEEIFEKPTRELV QGMRAAIYDKLDEDGIIAPGTRVSGDDVLIGKTITLPANEDELEGTAARFSKRDCSVFMR RSETGIIDQVMITINNDGYKFCKIRVRTVKKPQIGDKFASRHGQKGTCGITYRQEDMPFT SEGITPDIIINPHAIPSRMTIGHLIECLQGKVAANKGEIGDATPFNDTVNVQKISNLLHQ YGYQQRGNEVLYNGFTGRKLNAQVFLGPTYYQRLKHMVDDKIHSRARGPLQILNRQPMEG RSRDGGLRFGEMERDCQIAHGAAQFLRERLFEASDPYRVHVCNFCGLIAIANLRNQTFEC RGCKNKTHISQIRIPYACKLLFQELMSMNIAPRMMT---ELPSGFSFENCKRNLILEQGF TAPKAYKTGTTIAGVIFKDGVILGADTRATEDTVVADKNCEKIHYISSNIYCCGAGTAAD TEMTTQMISSKLELHRLETGRKPRVCTANRLLKQMLYRYHGYISAALVLGGVDSTGPHLY SVWPHGSTDKLPYVTMGSGSLAAMAVFEDRFKPDMEQEDAMKLVQEAIRAGIFNDLGSGS NVDLCIITKKTDYRRTYQEANLKGVRQGSYTYKRGTSAVLKTEVKKIELEVL-SKVTFKI TLTSDPKLPYKVLSVPEQTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPAQNAGNVFL KHGSELRLIPRDRVG-MAFTFAAFCYIVALILTAVLIFFAIFHIIAFDELKTDYKNPIDQ CSSLNPLVLPEYFIHMLFTFLFLCSFQFGSLLFNLPLAVYHVHRYMTRPVMSSPGLYDPT SIMNADQLNRAQKEGWIKLAFYLLSFFYYLYSMIYVLVSSMGLLTILKKMKQKEKEVRLL MLGLDNAGKTTILKKFNGEDINTISPTLGFNIKTLEHRGFKLNVWDVGGQRSLRSYWRNY FECTDGLIWVVDSADRMRLQDCKQELHSLLLEERLAGSTLLVFANKQDLPGSLSSEDIRK TLDLDNIKSHHWRILPCSAVTGENLLDGVDWIIDDIASRIFTMD--KKKCCYYYDGDIGN YYYGQGHPMKPHRIRMTHNLVLNYGLYRKMEIYRPHKATAEEITKFHSDDYIKFLRCIRP DNMSEYNKQMQRFNVGEDCPVFDGMYEFCQLSTGGSVAGAVKLNKQAADIAINWAGGLHH AKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMSVSFHKY GEYFPGTGDLRDIGAGKGKYYAVNFPLRDGIDDENYETIFKPVMTKVMDMYQPSALVLQC GADSLSGDRLGCFNLTLSGHGKCVEFMKKWNLPILLLGGGGYTIRNVARCWTYETSIALN VEIANELPYNDYFEYYGPDFKLHISQSNMANQNTVEYMDKIKTRLFENLRMLPHAPGVQM QPIPEDALNEEDNPDERISIRASDKRIACEEEFSDSEDEGEGGRKDRQNYKPKAKKTAAY ECNICLDTAHDAVVSMCGHLFCWPCLHQWLETRPHRQLCPVCKAGIGKDKVIPIYGRGNP NPQDPREKLPPRPQGQRPEPETTGGFPGFGFGFQFSFGIGAFPFGIFTSSFNMSDNRPGP PPPGSAQHTEEQFLSRIFLWVAIIFIFWLIVA-HSLIFKQEQAHKDSIWTCAWGRNEKDG IENIVSGSIDDTVKVWKWADLDLRFVLEGHQLGVISVDINPTGTLAATSSLDSHVKVWDL ETGKLAKSIDAGPVDAWTVAFSPDSRFLASGSHTGKVNLFGVDSGRKETSMDTRGKFTMS IAYSPNGKYIASGALDGIVNVFDMTTGKLLEGHAMAIRSICFSPDSQLLVTGSDDGQIKI YDVEHANLAGTVSGHGSWVLSTAFSPDNTHFISGSSDKTVKIWNAGTRQCVHTFYEHTDQ VWSAKYNGSGTRVVSVSDDRALHVYNCPI-------------------DSWLTRKVFSEI AGYDSIPDPKVMVAGLVACRRLNDYALAIRFIENIHHKAQGFDKNLWAYIQQEITPAMQE LGISSLEEMGYEKPEKEVVDVFDMIVRVRGLPWSSTTEEVLKFFEGSNICGGENGIHFTF SREGRPSGEAFIEFESPDDVEIAMGKHNAHMGSRYLEVFRSKRSEMDWVIKRAGPNQDSC VRLRGLPFGCSKEEIAQFFTGLEIVPNGIMLPEDRQGRSTGEAYVQFANQTIAERSLGKH KERIGHRYIEIFKSSLSEAHAQYKSNTGHSVHMRGLPFQALQSDIQDFFTPLRLVKVEFE YGSNRPTGEANVDFESHADAVEAMKKHKCNMQHRYIELFYQDKDKPTQIRYSNLTAAKAV ADAIRTSLGPRGMDKMIQAANGDVTITNDGATILKQMQVLHPAAKMLVELSKAQDVEAGD GTTSVVVLAGSLLDYSAKLLGKGIHPTTISESFQKASAKAVEILETMVTPLQLSDRESLL KSASTSLNSKVVSQYSNIFSPIAVDAVMRVIDPATADNVDLKDIKMIKKLGGTVEDTELI DGLVFNQKLS-SGGPSKIEKAKIGLVQFCISAPKTDMENQVIVSDYTQMDRVLKEERNYI LNIVKQIKKAGCTVLLIQKSILRDAVSDLALHFLAKMKIMVVKDIEREDIEFVCKTLACR PIASLDHFVAENLGSADLVEEVPAGTDKIVKITGIANPGKTVTVLLRGSNKLVLEEADRS LHDALCVIRCLVKKKALIAGGGAPEIELSIRLMEYANTLAGMEQYCFRAFAEALEVIPFT LAENAGLNPIAAVTELRNRHAEGEKTAGINVRKGAITNILEENVVQPMLVSTSAISLAAE CVRCILKIDDIV---MILLEFHNRIVQETLISKFKNAQEGSKPDTVDVTCADFDGVLYHI SNPDGDKNKLLVSISLKFYTDLQAHGADTLIKREYCDYLTSPEAGYNVSLLYNESVPQDY EEVAKKAALLKRNCFASVFEKYFDYQQKRERAVIHYRDDETMYVEAKKDRVTVIFSTIFK DNDDVVIGKVFMQEFKEGRRKYQQAPQVLFSHREPPQELQDTDARTGDNICYITFVLFPR HAARDNTINLIHTLRDYLHYHIKCSKAYIHQRMRAKTSDFLKVLNRARPENKEKEKKTIM LRFCPTCANLLFVEEGDKGYRFACHTCPYIKNITRKISHKKYPKLKEVDDVLGGAAAWEN VDSTEETCPKCEHNRAFFMQIQTRSADEPMTTFYKCCSMACGHRWR------MKDEDRMF LNLFGRHDWRLKGSMALGNWYKTKEILLKGPEWILKEISASGLRGRGGAGFPTGMKWGFM NKPSDGRPKYLVVNADEGEPGTCKDREIMRHDPHMLVEGCLVAGRAMGARAAYIYIRGEF YNEASNLQIAINEAYKAGFIGNNACGSGYDFDVYVHRGAGAYICGEETALIESLEGKQGK PRLKPPFPADVGVFGCPTTVANVETVAVAPGICRRGGEWFASFGRERNRDVLMDFDALIQ AQTGLGTAAIIVMNKQSDVIRCIARLIDFYKHESCGQCTPCREGCGWMKKVMDRFVTGDA EEREIDMLYELTKQIEGHTICALGDGAAWPVQGLIRHFRPVIVERMKQF----YSQDQVE DINQTLNQTRSQRVRAAMFPETLPEGVQIPSTQIHPDQPTAVQRLSEPSQMLKHAVVNLI NYQDDADLATRAIPELIKLLNDEDQVVVTQAAMMVHQLSKKEASRHAIMNSPQILAALVR AMNNTDDLEITRCAAGTLHNLSHHRQGLLAIFKSGGIPALVKLLSSPVESVLFYAITTLH NLLLHQEGSKMAVRLAGGLQKMVALLQRNNVKFLAITTDCLQILAYGNQESKLIILASGG PGELVRIMKSYTYEKLLWTTSRVLKVLSVCQSNKPAIVEAGGMQALAMHLGHQSQRLVQN CLWTLRNLSDAATKVDALEGILQVLTQLLSSNDINVITCAAGILSNLTCNNQRNKVIVCQ VGGIEALVRTIMQAGDREDITEPTVCALRHLTARHPEAEMAQNAVRLHYGLPVLVKLLHP PSRWPLIKAVVGLIHNLALCPANHAPLREHGALPRIVQLLIRAHQDTQRGGPSLVDGVRM EEIVEGTGGALHILAREPHNRAVIRGLNCIPLFVQLLYSPIENIQRVAAGVLCELAADKE GAEIIEQEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSMELTSSLYRGD QMSASFNWMIVRNNSSFLMKRGQFSREAGNLKGKNTFRFNGLIRDRTIAIQPAKTGKGIT VTTRNGQKRPNKRTFNTNINKDGRHTLKGVSNIMKSGKFDGKTHMAALRKTSAILRSQKP VVVKQRTDEPYYCSQQIAIPTDLPDILKQFTKAAIRTQPKDVLAWSAAYFRAMSNGETPP VKERLEMPVATQKTDSGLTPGILKVLNRQLGPKKTIPLSTVEEKWLDLALPKEQFDDIVR IGSFGGEIEWNKFLAIATSALAEGMAQSMKGLCDILTSDPDGGPSRIPFPLFKELYTYLA QIDGEISQQQINDVIDHLQYHVNKQEGYVQPRNFLSSECPKLS--------EEAMEQVKQ QIAMANLQELIQKITEKSFKKCVTKPGSSLDNSEQKCIAMAMDRYMDAFDVVSKTYVSRL QRE----MNRLFGRGKPKEPPPNLNDCISNIDSRGESIDKKVARLDAELKKYKDQMKKMR EGPAKNTVKQKAMRVLKQKKMYESQRDQLSNQSFNLEQQNFAISSLKDTKTTVDAMKVGV KDFKKAYKHVNIDQIENMQDELEDLMEMADEVQDVMGRSYGMPEVDDDELEAELDALGDE IGFDEDTTYLDDAVAAPSAPVGDPG-DSM--RGDVPVDEFGLPQIP-------------- --RNIVCTVNLNCKLDLKKIALHARNAEYNPKRFAAVIMRIRDPRTTALIFSSGKMVCTG AKSEDQAKLAARKYARIVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHSQFSSY EPELFPGLIYRMVKPKIVLLIFVSGKVVLTGAKVRTEIYEAFDNIYPILKGFRK------ ---------------QDEEEFHYNVLSADEIVKFMVDTIKEVNAVVQIPATITRILLNHF KWDKEKLMERYYDGDQERLFSEAHVVNPHKRDSELICEICCLGKVADMTGLECGHKFCAE CWTDYLTAKIMDEGMGQTISCAAYNCDILVDDATVMSLLKEPKVRLKYQQIITNSFVDCN RLLRWCPAPDCGHVLKVKYYDCKPVKCSCKHIFCFACGENWHDPVRCVWLKKWIKKCDDD SETSNWIAANTKECPKCNVTIEKDGGCNHIVCHNCKADFCWVCLGPWEPHGSSWYNCNRY NEDEARKARDNQEKSRSALQRYLFYCNRYMNHMQSLKFENKLYASVKTKMEEMQQHNMSW IEVQFLQKAVDVLCQCRQTLMYTYVFAYFLKKNNQSIIFEDNQKDLENATEQLSEYLERD ISSEMLHDIKQKVQDKYRYCESRRKVLLDHVHEGYEKDLWDHFDMASTDGKLSTTERIVK SVPFPPSHKLTMSEVFDAKGKPRPDVLKQHFILEGRVTEDVGIRLINEGAAILRQEKTMI EIEAPVTVCGDIHGQFYDLMKLFEVGGPPSTTRYLFLGDYVDRGYFSITERVYDACMEAF DCLPLAALMNQQFICVHGGLSPEIHTLEDIRKLDRFKEPPAFGPMCDLLWSDPLEDFGNE KTSEHFTHNTVRGCSYFYSYAACCDFLQQNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSL ITIFSAPNYLDVYNNKAAILKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVT EMLVNILNICSDDELMTEGDENVDAAVEARKDVIRNKIRAIGKMARVFTVLREESESVLQ LKGLTPNGLLPLGALSGGKETLSTALSGFDPTHKISGFEEAKCLDKMNERMPPRKGFRGR GGGDRGFRGGRGGGGRGGFGGRGGGGRGGRGGMAGGKQVIIEPHRHQGVFIARGKEDALV TKNMTPGETVYGEKKISVEENIKIEYRAWNPFRSKLAAAILGGVDHIHIAPGSKVLYLGA ASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINVAKKRPNIIPIIEDARHPHKYRMLMG MVDTIFADVAQPDQARIVALNAHNFLKNGGHVVISIKANCIDSTAEPEAVFADEVNKLKS EKIKPQEQLTLEPYERDHAVVVGVYRAPPKK-------------------AGAGLGLLAA AGGLIYGATHSFYTVDGGHRAIIFSRISGVKNDIYAEGLHFRIPWFEYPIIYDIRAKPRR ITSPTGSKDLQMVNISLRVLSRPESRNLPTIYKQLGQDYDERVLPSICNEVLKSVVAKFN ASQLITQRQQVSLLVRRELLQRAKDFNLILDDVSITELSFGREYTAAVEAKQVAQQEAQK AQFFVEKAKQERQQKVVQAEGEAEAVRLIGQALSTNPGYLKLRKITAAQNVARTIAQSQN RVYLNAGSLMLNLNEDSFD----SYTGSSSEEDDINPREKQQKTPKGFTDFCVKIDHAAF GRREIEIAEQEMPGLMALRRRAESDKPLSGAKIIGCTHITAQTAVLIETLISLGASIRWA ACNIYSTQNEVAAALAENSQPIFAWKGENEEDFWWCIDKCVNAEGWQPNMILDDGGDATH LMLKKYPAMFNMIKGIVEESVTGVHRLYQLSKSGKLSVPAMNVNDSVTKTKFDNLYSCRE SILDALKRTTDVMFGGKQVLICGYGEVGKGCGAALKGLGAIVMVTEIDPICALQACMDGF RVVKLDEVIRQIDILITCTGNKNVVNRQHLDRLKNGCIVCNMGHSNTEIDVTSLRTPELT WEKVRSQVDHIIWPDGKRIIMLAEGRLVNLSCSSVPSFVVSITATTQALALIELFNAPQG RYKQDVYLLPKKMDEYVASLHLPTFDAHLTELSDDQAKYLGLNKAGPFKPNYYRYPDPDA IKMFIGQIPRGMDENDLRKMCEEFGPVFQLNVLRDKVTGQSKGCCFVTYYSRKSALDAQN ALHNIKTMPGMHHPIQMKPADSEKRNVEDRKLFVGMLAKKLNENDVRMMFAPFGSIEDCT VLRDQNGQSRGCAFITYANRQSAQNCIKNMHHSQTMEGCSSPLVVKFADTQKEKEAKKLQ QMTNNVHLQLTGGTAGGFATVVVGQPLDTVKVKLQTFPTLYRNAFHCFKQTYAQDGFHGL YAGTVPSMENAVLFCFYGMCQKLVAGAAFFSSFALCPTELIKCRLQALTREILHKEGISG LYKGLTSTFLREMPGYFVFFGGYEISKVLLTPKDGDKENIGIRTIICGGVGGASLWIVIF PADVVKSRIQIRTEGIAALYNGLGPTLVRTFPATGALFLAYETTKKYLS----------- -IKSNIFKINSGANSIDKAMKSIGTDRDSVQLRDKIHETSQNISKLVQDSMRQLKVVGN- KPADKQQKIQLSKLRNDFQESVERFQGLQKMATEKVKSSVVEDDLALIREREERIRQLES DILDVNEIFRDLGALVSEQGETLDTIEANVERGNVEQANSQLSQAAVYQKKARKKKCCLL VILLVVAIVITIIIVVSVKMVNVTKGVLVECDPAMKQFLLHLDEKNALGRKFVIQDLDDT HLFISSDIIEILQTRIDDLMDKLSFPLSGKKDQAPTPQEGIQRLRDIEEMLTKKSDFLEK KVDQELATAKKRVALQALKRKKRYEKQLQNIDGTLSTIEYQREALENASTNTEVLKVMGS AAKALKGAHNNMDVDKVHDLMDEVAEQNEIANEISDAISNPIGFGQDVDDDDLMAELEEL EQQDIEEQLLDVT-LPSVPVSEDDEMNQLAAWASSMGKFHNRVRQILMASGSTTFTKIVN KWNTALIGLMTYFREAVVNTQELLDLLVKCENKIQTRIKIGLNSKMPSRFPPVVFYTPKE LGGLGMLSMGHVLIPQSDLRWSKQTDVGITHFRSGMSHDEDQLIPNLYRYIMPWESEFID SQRVWAEYALRTDMIQALGGVEGILEHTLFKGTYFPTWEGLFWEKASGFEESMKYKKLTN ASKDVMDGATTQKYWIDVQLRWGDYDSHDIERYARAKFLDYTTDNMSIYPSPTGLLIALD LAYSLHSAYGNWFPGSKPLIQSGMAKIMKANPALYVLRERIRKGLQLYSSEPTEPYLSSQ NYGELFSNQIIWFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSV WAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKG SELQLPFQACLKVEKFGDLILKATEPQMVLFNLYDDWLKTISSYTAFSRLILILRALHVN NDRTKIILKPDKTTITEAHHIWPTLSDEEWMKLEVQLKDLILADYGKKNNVNIASLTQSE IRDIILGMEISAPSAQRQQIAEIEKQTKEQSQLTATTTRTVNKHGDEIITSTTSNYETST FSSKTEWRVRAISATNLHLRTNHIYVSSDDIKETGYTYILPKNILKKFIIISDLRAQIAG YLYGYSPPDNPQVKEIRCIVLPPQWGTHQTVHLPNILPDHAYLKEMEPLGWLHTQPNELP QLSPQDISTHAKVMADNTAWDGEKTVIITCSFTPGSCSLTAYKLTPTGFEWGRQNKDTGN NPKGYLPSHYERVQMLLSDRFLGFFMVPSTCSWNYNFMGVRHDPNMRYELQLANPKEFYH EVHRPSHFLNFSTMEDGADREDMYNVYTQSRKNLAINKNTKVICQGFTGKQGTFHSQQAI DYGTRLVGGVSPGKGGSVHLGQPVFNNVKEAREATGADATVIFVPPPFAAAAILEAIDAE MPLIVCITEGIPQQDMVRVKHKLIRQGNSRLIGPNCPGIIKPGECKIGIMPGHIHQRGRI GIVSRSGTLTYEAVHQTTEKGLGQSLCVGIGGDPFNGTNFIDCLEVFLADPGTDGIVLIG EIGGQAEEKAAEYLRNNNGDNAKPVVSFIAGVTAPPGRRMGHAGAIIAGGKGGAEDKIEA LREAGVEVTMSPAQLGSTMIQAMSKSRKPNSEALRCTICEERLEDTHFVQCPSVIEHKFC FPCSKDSIKRQGAGSEVYCPSNKKCPLAGSSVPWAFMPGEIVTILGYDRVVEVGRVVFIA YGPDRGKLAVIVDIIDQNRALIDGPASGVVRKEIGYKAINLTRFKLIQKGICTKALKKVW AREKMEEKWAGTAWAKKLDSRQKREAMSDFDRFKVLKAKQARTRLINEEFNKLKASADKT CPLLLRVFCSLGRHHQTMEFARANTPANELQIYTWMDATLKELTSLVKEVNPDARKKGTF FDFAIVYPDPRTPTYRLREIGTTCCGKKSTDDNVTLASKKFQIGDYLDISISPPRGLGKT LQTISLLGYMKHYRNIPSPHLVIVPKSTLSNWMNEFKRWCPTLRTVCLIGLAEKRAEIIR DIILPGEWDVTITSYEMVIREKSVFKKFNWRYLIIDEAHRIKNEKSKLSEIVREFKSTNR LLLTGTPLQNNLHELWALLNFLLPDVFNSAEDFDSWFNTNNCLGDQQLVERLHAVLRPFL LRRIKSEVEKSLLPKKEVKVFVGLSALQREWYTKILMKDIDIVNGAGKLDKMRLLNILMQ LRKCCNHPYLFDGAEPGPPYTTDKHLFENSGKMVILDKLLPKLQAQDSRVLIFSQMTRML DILEDYCFWRGYDYCRLDGQTPHEDRQNSINDFNSPGSKKFIFMLSTRAGGLGINLATAD IVIIFDSDWNPQADLQAMDRAHRIGQKKQVKVLRFITENTVEERIVEKAELKLKLDSIVI QQGRLVDQAANKEVLTMIRHGASHVFASKDSEITDADIDQILEKGEQKTAELKSKLDSLG ESSLRNFTMEATDNSIYNFEGSDYREKQKIGGIG-WIEPPKRERKANYAVDAYFREALRV NEPKAPKAPRPPKQPNVQDFQFFPPRLFELLDKEIYYYRNSIGYRVPRNPELGSDAGKIQ MEEQQRIDDAEPLNEEELAEKEELLKGFTNWSKRDFQQFIKANEKYGRDDIDSIAREVEG KTPEEVIQYSTVFWERCNELQDIEKIMAQIDRGEARIQRRIGIKRALDVKMARYRAPFHQ LRIQYGTNKGKNYTEEEDRFLVCMLHKLGFDKENVYDELRQAVRQAPQFRFDWFIKSRTA MELQRRCNTLITLIERENLELEEKEKAEKRKSKGISWAEQVEAGDE-GLPPSSEDFDEKN GIKTITEYKYNEDNKLVKMVKTYKVETRKVSKSIARRKNWKKYGLAERDPPGPNSANTIE EINMQFINSRDQKEEDPLAKLKVQCRICKGDHWTTKCPYKDTLAPLQEHLKIGGKYVPPS LRDGANKRGETMAQDEAATIRVTNLSEETRETDLQELFRPFGPISRIYLAKDKLTGQSKG FAFINFHRREDAARAIAGVSGFGYDHLILSVEWAKPSMSESYDFLFKFLVIGSAGAGKSC ILHQFIESKFKQDSNHTIGVEFGSKVVNVGGKAVKLQIWDTAGQERFRSVTRSYYRGAAG ALLVYDITSRETYNALTNWLTDARTLASPNIVIILVGNKKDLEAEREVTFLEASRFAQEN ELMFLETSALTGENVEETFLKCARCILTKIESGELDPERMGSGIQYGDASLRRLQLRRPD CSCLLRPSEKQKLETSQWPLLLKNFDKLNVLTNHYVPIPSGCSPLKRSIEDYVKSGFINL DKPANPSSHEVVAWAKRILKVDKTGHSGTLDPKVTGCLIVCIERATRLVKSQQGAGKEYV CIFHLHSPVEDEQKVAKNIERLTGALFQRPPLISAVKRQLRVRTVYESKMLEYDKDKGMG VFWVSCEAGTYIRTMCVHLGLFLGVGGQMQELRRVRSGINSEKEGLVTMHDILDAQWLYE NHKDESYLRRAIKPLEALLTSHKRVIMKDTAVNALCYGAKIMLPGVLRFEDGIEIGQEIV IITTKGEAIALAIALMTTAVMSTCDHGVIAKLKRVIMERDTYPRKWGLGPKASIKKKMIK SGLLDKFGKPTDKTPKDWKNSYTDY----------------------------WNRKAPP KAQERRTTGAVNRAMQSGGVVDTRKKYAAATNKHVTTDKNTAKLDRETEELHHDAIDRSV AQLIQKGRSNKGLTQKELATRINEKPSVVNDYESGKAIPAQGILAKMERTLGLRLRGANK GQPLEPKMLKPKVLTQVLSQANTGGVGSTLLLNNEGALLAYSGYGDKDASVVSAIASNIW IAYTKAGTQGLGDPNLNCILTECNEGKLGITKVANLLLCMCTKESVGFGMLKAKLAALAE YLQDPLSQVASSGVATARISSKKQTLEDAYSPPANFLEIDVGDPQGKKRYTDYEVRMRTN LPVFKLKESITRRRYSDFEWLRNELERDSKIVVPPLPGKALKRQLPFRGDDGIFEKEFID ERQKGLEQFVNKVAGHPLAQNEKCLHMFLQEPVIDKNYVPGKIRTT--------EVGQLE PIKEEGKYEVGQLFLHKVLGYRGIVLNPWRVTVYDHDKVTKDSSQVTGKKQTYYEVLMDE RDYPYIRIRAESVTFIEQVEYFKL-CFSGLDYVAHDDIIPYHSKEKTPIVNQCFNKFLLY DPPFVMTEMLRTWHDKNITELQLSEVRRETTENIRVTVIPFYLGSFHCYFLFQWRYCVRL ENLGEETVQLRERAWKIMSLTGSIDRVTGRGVLGEQPILSGEDPAYQYSSHVVLHAGSGY MWGSYRMERRDGTSFNCKIPKFYLESK----MATSKGANTYNRQNWEESEFPLLCQTCLG DNPYVRMMKEKHGKECKTCNRPFTVFRWCPGARMRFKKTEVCQTCSQMKNICQTCLLDLE YGLPVQVRDAALRVQDSLPKSDVNKEFYMQNVEREIENSDGTNPVGAIAN-KVPSDMLLK LARTSPYYKRNRPHICSFWVKGECKRGEECPYRHDKPTDPDDPLANQNIKDRFYGTNDPV ADKLLRRYQDMPKLEPPEDMDVFLTIRQKKTTIFTDAKESTTVNEVKKIIEGILKVAPEN QKLFKDNKTLSDCGFTSATARAQQPATIGLATREFENLEITPLSNPPELPDVMKPQESTS SHAQE---RYQSVLMRDRFDRHKELDVSKAKKLLALGEEELFRKSHNKPLQYNNCPGGIA YERSPIPPDSIFDYWHPLEKALFPKYFAKREQMKQEYIERWEAKYGRS-MDDYTKIEKIG EGTYGVVYKGRHKKTSRLVALKKIRLESEEEGVPSTAIREISLLKELHHPNIVCLEDVLM QENKLYLVFEFLSMDLKRYMDTIPNGQFVDKMLVKSYTYQILQGILFCHQRRVLHRDLKP QNLLIDNKGVIKLADFGLARAFGIPVRVYTHEVVTLWYRAPEILLGSPRYSTPVDMWSIG CIFAEMVTKRPLFHGDSEIDQLFRVFRTLTTPTDETWPGVTALPDYKNNFPKWKTNQLAS SVDNVGLDLLLRTLEYDPAKRISAKEALNHSYFAARIFNAIGRVGVGLFVTGAVAQSALY NVDGGHRAVIFDRFRGIIPDVVGEGTHFLVPWVQKPIIFDVRSRPRNVVVVTGSKDLQNV NITLRILFRPVVKELPRIYTNLGVDFDERVLPSITNEVLKAVVALFDAGELITNREVVSQ KVSEELVERAGQFGIVLDDIALTHLTFGQEFTTAVESKQVAQQEAERARYNVEKAEQYKI AAIITAEGDAKAAELLAKSFGDAGEGMVELRKLEAIEDITVNLSKARNVTYLPSGQQTLL SLPMKLISSSQTVNIPKGVSICVKSRQITVKGPRGTLIKKFRHAGIHIYMKDHRHVTVEK FFGTSKQLATVRTICTHVENMIKGVVKGYLYKMRAVYAHFPINVVITDEGQRVEVRNFLG EKYTRIINMMPGVLISGSPGQKDEYILKGNDIEMVSRSAALIQQSTAVKEKDIRKFLDGI YVSEKTTVEQDMGCVTSSEDKVAMERSKQIDKGLKADGEKSSREVKLLLLGAGESGKSTI VKQMKIIHEKGYSQEECLQYKPVVYSNTIQSMIAIIRAMGLLKIDFGHPDRAEDARKFFS LAGNADEGELSPEVATIMKKLWKDSGVQECFSRSREYQLNDSAEYYLNAMDRISHTGYIP TEQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFIVAMSE YDLTLAEDQEMNRMMESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTVCFPE FSGSNTYEEAAAYIQMQFNKRKDTKEIYTHFTCATDTNNVQFVFDAVTDVIIKNNLKDCG LF-------------------------------------------SSALFFNYNTQLGPP YHVLLDTNFINFSIKTKLDVFKSMMDCLYAKCIPYITDCVMGELEKLGRKYKVALRIIKD PRFKRLPCLHKGTYADDCLVQRVTEHKCYIVATNDKDLKRRIRKIPGVPIMYTTRRKYSI ERMPDAYGAP-MSFSSDEVNFLVYRYLQESGFVHSAYTFGIESHISQTNINGALVPPAAL LNIIQKGLQYTEAEISIAEDGTVRPMESLSLIDAVMPEVVESKKQAAAKNTNGEDHTDSM EVDGTVDIPTSKTTVLRGHESEVFICAWNPANDLLASGSGDSTARIWNMNDNSSANQLVL RHCIQKGGTEVPSNKDVTSLDWNCDGTLLATGSYDGYARMWSTDGRLVNTLGQHKGPIFA LKWNKRGNCILSAGVDKTTIIWDASSGSCQQQFAFHNAPALDVDWQSNNSFASCSTDMCI HVCRLGCDRPTKTFQGHTNEVNAIKWEPQGNLLASCSDDMTLKIWSMKQDTCVHDLQAHN KEIYTIKWSPTGPSTNNPNASLILASASFDSTVRLWEVERGTCLHTLTKHQEPVYSVAFS PDGRYLASGSFDKCVHIWNVQSGSLVHSYRGTGGIFEVCWNHRGDKVGASASDGSVFVLD LRKSNPDLASLFECPVCFDYALPPIMQCQSGHIVCQTCRQKLRMCPTCRGELGNIRNLAM EKVASTVMFPCKYSNNGCQNTLLHTEKTEHEETCEFRPYCCPCPGASCKWQGSLEQVMPH LLQIHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHNFMLVLEKQEKIDGLQLFYA IVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHDGIQSAILSSDCLVFDTNIAQLF ADHGNLGINVTISVCMAAQTFQQEYLQMPPITRAYTTACVLTTVAVQLDVITPFQIYFNP DLIFRQYQIWRLVTNFLYFGPIGFNFLFNIIFAYRYCRMLEEGSFRGRTADFVFMFLFGG VFMILVINLVFLGSVFTIMLVYVWSRRNPYIRMNFFGLMNFQAPYLPWVLLGFSLLLGNS VIIDLMGIAIGHIYYFLEDVFPQQPNGFKILKTPQFLKYIFDAAPEDPNYNPLPPGGFNW GQGLELLSDQGFRIDGRRPNELRKIQCRLGVFKQSDGSAYIEQGNTKVLAAVYGPHEVRG SRSKHDKVLVNCQYSMATFSTGERKKRPRGDRKSTEMTMHLKQTFDAVILTSLYPRSQID IYVEVLQSDGGNYCASVNAATLALIDAGIPLKDYVCACSAGFVNDTSIVDISYLEESGGP ELIVATLPKSEQIVFLEMNSRLHEDNLSKVLDVASKGCKDIYEILDRAVREMTGSYYFVI VGHHDNPIFEMEFTAPSKQNDPKKDDFRHLNQFIAHAALDLVDEQMWSTNNMYLKVVDKF NEWFVSAFVTAGKMRLLMLHEVKNEEGIKNFFTEVYDTYVKHAMNPFYEINTPIKSTAFE RKVQVFGRKYLPSQVRYAHTDVKIPDFDPYRRNSLHSERRAFSYLTVGSAGVATVYCSKY LVETFISSMSASADVMALSKIEVKLDAIPEGSSATFKWRGKPLFIRHRTPQEIATEKGID INTLRDPQHDEDRAQKPEWLIVIGVCTHLGCVPIADAGEFGGYFCPCHGSHYDTSGRIRK GPAPLNLEVPEYSFPSEDLVIVGMSRQSARGTDIRKVNGELFTLTYGALVSQLMKDYEND EEVNKQLEKMGYNIGVRLIEDFLARANSNRCNDFRETADIISKVAFKMYLGITPVISNWS PSGDEFSLLIENNPLIDFVELPEGHSSLNYSNILTGVLKGALEMVQMDVDVKFVQDQLKG DNLTELRLKFIKRLEDAIPAGEDENVKEFLAKAKEDFTQKWDHPSQNNACLDDFERIKTL GTGSFGRVMLVQHKANKDFFAMKILDKQKVVKLKQVEHTLNEKKILQAINFPFLVRLEYS FKDNTNLYMVLEFVTGGEMFSHLRRIGRFSEQHSRFYGSQIVLVLEYLHHLDIMYRDLKP ENLLLDSLGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIY EMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLRNGVN DIKQHRWFNSTDWIAIYQRKVEAPFVPKHKGAGDTSNFDDYEEEALRISSTEKCAKEFAD FMFGDCVLIVAISICTALLGEGLTWVLVYRTEKYKKLKAEVEKQSKKLEKQKET---GAD VANKKKYERQEEKLKTNNRDLSFVKMKSMFAIGFAFTALLSMFNSIFDGRVVAKLPFTPI SLLQNISHRNLGGEDYTDCSFIFLYILCTMSVRQNIQKLLGLAPSRSANKQGSGFFGACM KYFEHWTENEQTEFVEHLLSHMCHYQHGRINAYLRPMLQRDFISALPAKGLDHIAENILA YLDSVSLCSAELVCKEWYRVVSEGNLWKKLIERKVRTDSLWKGLAERRGWGNTLFKPKPG EPAKDHKFYRGLYPSIIEDIDRIEDNWRTGRHTLQRIHCRSETSKGVYCLQYDDEKIISG LRDNTIKLWDRSQLECVKVLTGHTGSVLCLQYDEKIIISGSSDSTVRVWGVKTGEMLNTL IHHCEAVLHLRFCDGIMVTCSKDRSIAVWDMQSPTEINLRRVLVGHRAAVNVVDFDNRYI VSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYHDRLVVSGSSDNTIRLWDIEYGACL RVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRSPAGTLCLRTLVEHSGRVF RLQFDEFQIVSSSHDDTILIWDFLNMAKTYDYLFKLLLIGDSGVGKTCLLFRFSEDAFNS TFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITSEKS FENIRNWIRNIEEHASKDVEKMILANKCDMNDRRQVSKERGENLAVEHGIKFMETSAKAS INVDEAFFTLARDIKGKMDRR-TEGETSADRNVEMWKIKKLIKSLEAARGNGTSMISLII PPKDQVSRVNKMLADEYGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVIYCGT IITEEGKEKKVNIDFEPFRPINTSLYLCDNKFHTEALTALLADDNKFGFIIMDGNGALFG TLSGNTREILHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAEVAVQLFITNDKP NVAGLVLAGSADFKTELSQSDMFDQRLQAKILKIVDVSYGGENGFNQAIELAADSLANVK FIQEKKLIGRYFDEISQDTGKYCFGVEDTLRALEMGAVDTLIVWENLSITRFVVRDHSTE ENRILFLQPDQESDKTNFTDKDTGVEMEMVEQVSLLEWFANNYKNFGATLEIITDKSQEG AQFVRGFGGIGGILRYQVDFQMFHPDLQEYDDFDIDDYITRCSQPMVGKRNSHDERYIQM IMDANAQSHKLYILDARPTVNAVANKAKGGGFENEDSYQNAELVFLDIHNIHVMRESLRK LKEVCYPNIDEAHWLSNIESTHWLEHIKQILAGAVRVADKVESNKTSVLVHCSDGWDRTA QLTGLAMLMLDPYYRTIKGFEVLIEKEWLSFGHKFAQRVGHGEDKHSDADRSPVFLQFMD CVWQMTKQFPNAFEFNEHLLITILDHLYSCLFGTFLYNCEQQRAKEKLKHNTMSLWSFVN CQLEEFTNPLYKHVLFPVASLRRIELWVGYYCRWNPRMRPQEPVHLRNRELLILKQQLQQ KVNDLQKELQNKN---RAFVPHIPFDLLQCESAFPKSKPPSDEKAFTEALLKRNADLTPN AAEQASILALVTKIQSVLDNLVIAPGAFDSAQIEEVRQVGSFKKGTMMTGSNVADIIVML KTLPTKEAVAALGNKVLEELKSQESTEVLSMLTTESGFEISSADASVKCLISTIPPNLKK LDPELHLDGKVMQGHLAGIRHARWFEENAGHSSIKVLIRLLRDLRNRFEGLQPLTPWIID LLAHYAVINNPSRQPQPINIAFKRCLQLLSAGFFLPGSVGITDPCEQGTVRIHTVMTLEQ Q-AICYTAQTLLRVLSHGGYKQILGMEGNSSIATEMSVWEGVVVTPSDKAYEKSEDVVRL IEQYLKENNLLKTLSVLQEESGISLNTVDSVDGFISDINNGHWDTVLQAIQTLKLPDNKL IDLYEQIVLELIELRELGAARSLLRQTDPMLMMKHNQPDRYIHLENMLARSYFDPREAYP EGQTKEKRRTAISQALAGEVNVVPPSRMLALLGQSLKWQQHQGLLPPGTTIDVFRGKAAV KEQDEEKYPTQLSKTIKFGQKAHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLR YQAQDNFMMMDDAVLCMSFSRDSEMLATGSQDGKIKVWKILTGQCLRKFEKAHSKGVTSL YFAKDNSQLLSASFDQTIRMNGLKSGKTLKEFRGHSSFVNDAVFTPDGHHIISASSDGTI KVWNIKSTECQSTFKSLGGTAGTDITVHSIHPLLRNAEQFVVCNRSNTVVLMNIQGQIVR SFSSGKREGGDFVCATVSPRGEWIYCVGEDMVLYCFSITTGKLERTLTVHDKDVIGIAHH PHQNLISTYSEDGLLKLWKP----------------------WNVLKVEMAPPADMPEMA ATAQKLLKAFTYKFINLTFREMLIIVIDLILCFFLGEIIGKRSLVGYKL---------NV PKVYTQLPTNDEPVLLKLREDSRSAFLQRRSREILDNDELQKLWFLLDKHHTPPILEGEQ MISYDDFLLVAEKAGTKCKSFFKPSVFAQLVQTDPYGRISIMQFFNYVMKKMWLYQTRIG LALYDVAGQGYLKECDLETYILELIPTLPQLNGLEKSFYSFYVCTAVRKFFFFLDPVKTG KIKIVDILTCSFLDDLLELRDEELSKEIQESNWFSAPSALRVYGQYLNLDKDRNGMLSKS ELARYGTGTLTDVFLDRVFQECLTYEGEMDYKAYLDFVLTMENKREPQSLRYLFRILDIN YKSSLNVFSFNFFFRAIQEQMKLHGQEPVIFHDIKDEIFDMVRPADPYKITLEDLINCGK GDTVVSILIDFNDFWAYENREYELVRGQAFEVGPRYTKLLYIGEGAYGMVVSAYDNETKT KVAIKKISPFEHQTYCQRTLREIKILTRFKHENIIDIRDILRAKSADKMKDVYIVQCLME TDMYKLLKTQQLSNDHVCYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFG LARVADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDVWSVGCILAEMLSNRPLFP GKHYLDQLNHILGVLGSPSQADLNCIMNEKARGYIQSLPYKPKIPWTRLADSKALDLLDK MLIFNPQQRITVEQSLAHPYLEQYYDPADEPVAAEPFTFEMELDDLPKEQLKEMIFQETM TLKDRCLTPPKTTPEWVKFCKQLFGGFSLLLWIGAILCFIAYSIQASALEYPPGDNLYLG IVLAAVVIVTGCFSYYQEAKSSRIMDSFKNMVPQYAVCIRSGDKLNLKAEELVVGDVIDI KFGDRVPGDIRVISAHGFKVDNSSLTGESEPQTRTAEFTHENPLETRNLAFFSTNAVEGT CRGVVVKTGDKTVMGRIANLASGLEVGETPIAKEIAHFIHLITGVAVFLGVTFFIIAFIL GYYWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTI CSDKTGTLTQNRMTVAHMWFDGHILEADTTDDQSNAAYSRNDPTWNALARIAMLCNRAEF KTGQESVPILKKECNGDASESALLKCVELSIGNVTEYRRRNKKICEIPFNSTNKYQLSIH PNDPRMILVMKGAPERIMDRCSTVLLNGKETPLDDNFREAFNAAYLELGGLGERVLGFCD YVLPNEQYPPGYEFDPEGPNFPITGLRFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVT GDHPITAKAIAKGVGIISEGSKTVEDVASERGIPVEEVDPRDAKAAVIHGQDLRDMTPAQ IDEILRNHNEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIS GSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLFFILLD IPLPLGTITILCIDLGTDMVPAISLAYEQAENDIMKRQPRDPLNDKLVNERLISMAYGQI GMIQASAGFFVYFVIHGENGFWISRLMGIREAWDSRGINDLEDSYGQEWTYHQRKVLEYT THTAFFVSIVIVQWADLIICKTRRLSLFQQGMKNHRLTFGIFFETALAIFLTYCPGLDQG LRMQHLRFTWWLPALPFSLAIFVYDECRKYILRRRPGGFVERETYY-------------- ---------------ELHPPKMPWSHTGLFDSFDAASVRRGYFVYKQVCAACHSLNYLAY RTMVGAIFTEEEAKREAEEAVIVDGPDDEGHMFTRPGKLSDIFPAPYKNDEEARAANAGA LPPDLSYIVVGRHGEEDYIFSLLTGYVDPPAGVNIPEGLHYNPYFPGGAIGMAQALYNEI IEYEDGTPATQSQLAKDVTIFLRWAAEPNHDLRKKIAIKTFLVLLTLSVYYFKKYKWSVV KSVKTTWKRPDLPSKCTYTPDKIDQSPHRHIKQKPAIMPNILYNIGNTPLVRINRITEKE GVKCELLAKCEFFNSGGSVKDRIGLRMIEDAEAQGVLKPGDVLIEPTSGNTGIGLALAAA VKGYRCIIVMPEKMSMEKVDILRALGAEIVRTPTSAAFDSPESHIGVAKRLMEEIPNSHI LDQYRNPSNPLAHYDCTAEEILAACDNKLDMMVLTAGTGGTLTGIARKIKEKCPSCKIIG VDPAGSIIAEPEDTSFYEVEGIGYDFIPTVCDRSPVDKWYKSVDKDSFIMARRLIKEEGL LCGGSCGSAVYCAIKAIKDFGLKEGQRCAVVLPDSIRNYMTKHLSDDWLSQRHFMSDIGS EEEQGPYLGEYDGDRNEREERHGHGKATLPNGDTYEGQYEHGKRHGTGVYRFKNRARYIG EYNKNKKHGQGTFIYPDGSKYEGGWVDDQRCGHGKYYYVNGDTYEGEWQGHLRHGQGAYI YAATNTKYVGTWVNGKRESHGELIHANHKYVGTFKDDRMEGKGKYVFDIGCEQHGEYIMP DIMRLITKDLSEPYSIYTYRYFIHNWPKLCFLAKDKEKCVGAIVCKLDLHKKLVRRGYIA MLAIDSDYRRRRIGSNLVTKAIRAMISDDCDEVVLETEITNKAALKLYENLGFVRDKRLF RYYLNGVDALRLKLWLRNLNAIMFHLSPNQKKCLRDEIHKDVLVTGEYELSDAPGQKTHL TVTDSKEHILYSKEGASKGKFAFTTEEYDMFEICFETKMPGGGHGVDREISLILKHGVEA KSYEDIAKADKLKPLEVELRKLEDMSQSIVDDFAYMRAREEEMRDTNESTHTRVMYFSIF SMCCLFGLATWQVLYLRRYFKAKKLIEEMETGRTSSVGNDILGFTGNVVNKPDHGHLDWI KICEASAKVVTFIDLAGHEKYLKTTVFGMTGHAPDFAMLMIGANAGIIGMTKEHLGLALA LNVPVFVVVTKIDMCPPNVLQDTLKLLQRILKSQGCRKIPVMVQTKDDVICSATNFTSER MCPIFQVSNVTGENLELLKMFLNLLSTRVKSKPAEFQIDDTFSVPGVGTVVSGTLLQGNI RLNDNLLLGPDALGQFQPMVIKSIHRKRMPVKEVRGGQTASFALKKSAIRKGMVMVSPKL EPKACWEFEGEILVLHHPTTISVRYQAMVHVGSVRQTATILNMTEEHLRTGDKAHVRFRF IKNPEYIKPDMKMVFREGRTKAVGTIVKLHPHVCANTRQQRAAKKAQEQEKLCHVEDRYF YLFKVLRAHILPLTNVAFNKSGSSFITGSYDRTCKVWDTASGEELHTLEGHRNVVYAIAF NNPFGDKIATGSFDKTCKLWSAETGKCYHTFRGHTAEIVCLAFNPQSVIATGSMDTTAKL WDVLNTLNGHSAEIISLSFNSTGILLITGSFDHTVSVWDQQVHTLIGHKAEISSAQFNWD CSLIATGSMDKTCKIWDTDSGRCIGTLRGHEDEVLDVAFDYTGQHLLTASADRCYNAITH SKFEGHEGEISKICFNPQGTKVLTASSDKTARIWDPETGDCKQVLEGHSDEIFSCTFNYE GNTIITGSKDNTCRIWRGDVFMEKHWKSVINKSICDYFFEAQGKATNPEDVCPVINTPHH YLINIYRNNLYFVAVVTTEVPPLFVLEFLHRICDTFEDYFNECNESTLKEHYVIVYEILD EMLDNGFPLAVESNVLKELIKPPNFLRTITDTVTGKSTGVSGILPTGQLSNIPWRRTGVK YANNEAYFDIIEEIDAIIDKSGTTVTAETQGYIDCLIKLSGMPDLSLTFVNARLLDDVSF HPCVRFKRWENEKILSFVPPDGHFRLMSYHIGAQNMVAIPVYLRHTINYREGSGGRFDVT VGPKQTMGKTVENVILEVPFPKNVLNVTLTPNQGKYSFDPVSKFMTWDVGKIDTTKLPNI RGNISLQTGSPIPDSNPVINVQFTISQMAVSGIKVNRLDMYGEKYKPFKGVKYITRAGKF QVRTMATQVRPTTRFQPPDWFTNNYTISTNAERQRDASHQVRQEGRFLTNETDNQTKWDQ HSNNVRLADRVDHIRKWKEILEKTLADLDQEIADLSDSKELTEQALEAKNLPLDVAVECL TLREGRQGIDIVQDEAENQLHKEVEVIEGIRKNLQQRVSDSFEQICLLQEARQQIQADLQ DKNIALGIDIDQYNLTDRSPNISYKPDSLRVPKGSTTPQQWEDFSRYNKERADAEMQASG RLREAIHHTLQKTDNDLEAQKIATEFALRKRIHEFERAKDELEWQKKNTEDEIAELENDI RKLAEAIRAKTNPMKLAQTRLENRTYRPNVELCRDAPQYGLTDEVKQLEATKKALEEKLK QAQHALDGLEKNLHRINDDLALKNNSLMLDKRNMSVREKLERNLTLTGITNLKDFLADNI PKKQNEVKEFRKQFGSTKVGEVTVDMMYGGMRGIRGLVTETSVLDPDEGIRFRGYSIPEC QKLLPTAGGGEEPLPEGLFWLLVTGEIPTQAQADAITNEWNQRASIPNHVITMLNNFPTN LHPMSQFSAAITALNSESKFAKAYAEGVNKSKYWEYVYEDSMDLIAKLPTLAAVIYRNLY RDGSTPCAIDPKKDWSQNFSHMLGFEDPLFSELMRMYLTIHSDHEGGNVSAHTTHLVGSA LSDPYLSFSAGINGLAGPLHGLANQEVLVWVTKLQVTDQQMHDFIWNTLKSGQVVPGYGH AVLRKTDPRYMCQREFALKHLPNDSLFKLVAQLYKVVPDILLEQGKAKNPWPNVDAHSGV LLQYFNLKEMNYYTVLFGVSRALGCTASLIWDRALGLPIERPKSFDTPGLKKLV------ ---DKCASCEKTVYPQEKQEAGGKNFHKNCFKCTNCKMALKLNNYAQAHGILYCKKHFQE QVTAKNTQ-GHVFVHRDTDKNNPDIKFEFTAENQKRVEAIMANYPEGHKQAAVIPLLDLA QRQYGWTPISVMHTVADILKMPRMRVYEVATFYTMFNREPVGKYFVQICTTTPCMLGGVG SDVILDAIKENLGVKVGETTSDGMFTLSEVECLGACVNAPMIQINDNYYEDLTVDDTHRI LNELKAGKIPKPGPQSGQEWRFASEPKTGLTSLTEEPKGPGFGVRSDLMQAYEKLEKIGE GTYGTVFKAKNRDTHEIVALKRVRLDDDDEGVPSSALREICLLKELKHTNIVRLHDVLHS EKKLTLVFEYCDQDLKKYFDSCNGEIDPDAVKSFMYQLLRGLAFCHSHNVLHRDLKPQNL LINKNGELKLADFGLARAFGIPVRFYSSEVVTLWYRPPDVLFGAKMYSTCIDMWSAGCIF AELANAGRPLFPGNDVDDQLKRIFKLLGTPTEETWPGITQLPDYK--------------- ---------------------------------------VEKPFLEYSGPKDGVTYPIQG EC-TMPIEYCEYYPNYEKCKEWLERHLPQEFQKLTTKRQTRGGKGMLKAKKKAEPKGIKM WTQSRGKKKKITTLVGLADYDIDLKVASKFFANKFSCGASANDSGEIVIQGDVKDDLFDI LPEKWPQIDEDSINDLGDKK-RWTEDRSAAWEIVKESLCGTVEGRNSLLYGTPEIWKGYY FTPLEIGGLYSIHLHGWSDIYIPDKESLVTDAGKLFVLDSLLQRLKSEGHRVLIYSQMTR MIDLLEEYMWHRKHSYMRLDGSSKISERRDMVADFQTKSDIFVFLLSTRAGGLGINLTAA DTVIFYDSDWNPTVDQQAMDRAHRLGQTKQVTVYRLICKGTIEERIVQRAKEKSEIQRMV ISGGNFKPETLKPKEVVSLLIDDDEMEHKMSLETVPKDLRHLRACLMCSLIKTFEQFEYD GCDNCDEHLHMKNNRDNVYECTSSNFDGMIAMMGNEDSWVAKWQRIGRCVKGVYAISVTG KLSPRIVRELSRKGIVYRSRDTSMPDHAQYLTAEQQDELRKIANAIVAPGKGILAADEST GTIGKRFSSINLENTEENRRRYRELLFSSVAENISGVILFEETLYQKAKDGTPFVKVLQD KGIIPGIKVDKGVVPLAGTFSEGTTQGLDGLSERCAQYKKDGAQFAKWRCVLKIGPQTPS YQAMLENANVLARYASICQQNGLVPIVEPEVLPDGTHTLEEAQYVTEKVLAFQYKALSDH NIFLEGTLLKPNMVTAGQGCTVKYTAQQNAKATVEALSRTVPAAVPGVTFLSGGQSEVDA SINLNAINAKPWALTFSFGRALQASVIKAWAGQDANLGKAQAELIKRAKANGNASLGKYT PDGEGAAAQSLFIANHSYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIILLK EGTDTSQGVPQIISNVNACQAIADAVRTTLGPRGMDKLIVGDGGKAVISNDGATILKTLD IVHPAAKTLVDIAKSQDAEVGDGTTSVVLLAGEFLKEAKPYIEEKVHPQVVIRAFRKAGH LMIQKIKEIAIKIKKNPAELRELLEKCAATSLSSKLVAAQKDFFSKMVVDAVMMLDELLP LNMIGIKKVQGGALEDSMLVAGVAFKKTFSYAGFEMQSKTYTNPKIALLNIELELKAEKE NAEVRVNSVEEYQSIVDAEWKILYDKLETLYKSGAKVVLSKLPIGDVATQYFADRDMFCA GRVPEEDLKRTMKACGGSIQTTVQGLKLGTCENFEEVQVGCERYNVFKGCPQAKTCTIIL RGGAEQFMEETERSLHDAIMIARRAMKNDSVVAGGGAIEMELSKYLRELSQTIAGKEQLL MTALGKALEVIPRQLCDNAGFDATNILNKLRQKHAGTWFGVNVMTEDICDNFQGFVWEPS VVKINALTAAIESTCLILSVDETIRNPKAEGGPPGAGRGRGRPMKGNNVVPNGHFHKDWQ RYVKTWFNQPARKKRRHDTRLKKARRIAPRPAAGPLRPIVRCPTFKYNSKRRMGKGFSFE ELKAVKVSWKEALGIGIAVDFRRKNKSVESLQENVQRLKEYKSKLILFPRNKKKVRAGEA SSEEVKMATQLTGKLMPVKSSFKPDKARAVTAEEKKSSAYQQIVRARKEERFVG------ ---MPNIKVFSGTTHPDLARRICERLGIEPGKVVTKKFSNGECCVEVGESVRGEDVYIVQ SGCHEVNDMLMELLIMINACKIASACRVTAVIPCFPYARQDKKDKSPISAKLVANMITVA GADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIREHITDWRNCCIVSPDAGGAKRVT SIADRLNVDFALIHKERKKANEVASMVLVGDVKNRVAILVDDMADTCGTVCHAAEKLLEA GAQKVYSICTHGIFSGPAVTRINNSLLESVVVTNTIPQDQPMKLAPKIQTIDISIILAES IRRTHNGESVSYLFENVPLLSCRFYKNRFPEVEDVVMVTVRSIAEMGAYVHLLEYNNIEG MILLSELSRRRIRSINKLIRVGRSECVVVIRVDKDKGYIDLSKRRVSQEEVIKCEEKYAK AKAVSSILRHVAEILHYETNEELEELHMKTAWHFDDVYKKPGMAFEIFKHAVLNPETLDE CDIDDKTKAVLLENIKRRLTPQSVKIRADIEVACTNYEGVDAVKRALKKGLEFTTELLPI KINLIAPPQYVVTTQTLERSEGMARGQQKIQSQQKNAEKLAKSKTSQKKAAQNALVHTCT VCKSQMPDPKTYKQHFESKHPKNDLPDCLKEVMLGDLQTDMNKQGASVKTKGVCAACNKS VVGQVITALGKIWHIEHFTCAHCNNELGTQNFYERDSAAYCETDYHNLFAPRCGYCNGPI VDKCVTALNSTWHPEHFFCAQCGQPLGDEGFHEKDGKAYCRDDYYSMFAPKCGGCGRPIM DNYISALNRHWHPECFVCWDCHCPFGGGSFFDHEGLPYCETHYHAKKGSLCATCQKPITG RCITAMFKKFHPEHFVCAFCLKQLNKGTFKDQNDKPYCHPCFVKLFMRPLTEDETKIFFE KLSKYIGDNIKLLLDRPDGNFCFRLQKDRIFYVREDIMKKATCVDPKHLLSIGTCFGKFT KTKRIRLHITALDYLAPYAKFKVWLKPNAEQQFLYGHHVMKAGLGRITENTSQYQGVVVY NMNDLPLGFGVAAKSTELCRQCDPMSIVVFHQADIGEYIRSEEMLANQRKFFVGGNWKLN GDKQSVDGIIKFLNDGDENTEVVVSPPAIYLDYVRGKLVATSAQNCYKVAKGAFTGEISA AMAKDVGATWIILGHSERRHVFGECDELIGQKTKYVLEEGLGVIACIGEKLEERESNQTN EVVFRQTSASDWSKVVLAYEPVWAIGTGKVASPEQAQEVHASLRKWLADNVSAEVAQKTR IIYGGSVSAGNCKELGTKPDVDGFLVGGASLKPDFVQIINARDREGLLDPAWEKQQKKTF TAWCNSHLRKAGTSIENIEEDFRHGLKLMLLLEVISGEQLPKPDRGKMRFHKIANVNKAL DYIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIIVQNFHLSFKDGLAFCALIHRHRPDLI DYHKLSKENPLENLNTAFDIAEKYLDIPRMLDPEDMVNSAKPDERSVMAYVSSYYHAFSG AQQAETAANRICKVLKINQENERLMEEYEKLASDLLAWIKKTKPWLENRVTDNTLPGTQH KLEEFRDYRRKHKPPKLEDKAKLENNFNTLQTRLRLSNRPAYIPTEGKLVSDIADAWKGL ESAEKGFEEWLLSELQRLERLDHLAQKFRHKCEIHEEWAVGKEEMLESRDFKKCRLNELK AMKKKHEAFESDLAAHQDRVEQIAAIAQELNALDYHDVNRVNTRCQTICDQWDRLGQSTQ RRREGLEEAEKILERIDHLHLEFAKRAAPFNNWMDGAKEDLLDMFIVHTTEEVQGLISAH DTFKSTLGEADKEYTTIITLVQDVQRLAQQYNMT-PPDNPYTTLHAQDIANKWREVQELV PKRDQTLQQEMMRQQKNETLRRQFANKANSVGEWIEKRLDFVAAIGVHKGSLEDHLNEIQ HVEKECHGFRPHMEELERINQEVQESMIFENRYTQYTMETLRVGWEQLLTALARNINELE NQILTRDSKGISAQQMNEFKLSFSHFDKNKTSRLEPKEFKACLVSLGYNIRDDKQGEADF QRIMAIVDPNRTGYITFEAFIDFMTRETADTDTAEQVMHSFKILAGDKPFITAQILRQEL PPDQAEYCIQRMAPYSGRDAVPGALDYMSFSTALYGESDLNKLSIDKLDLKGKRVLMRVD FNVPLKDGNITNNQRIEAAIPTIKYALDNGAKSVVLMSHLGRPDGRPNAKFTLKPVSVVL EKLLKRPVMFLKDCVGAEVEGACANPEPGTVILLENLRFHLEEEGKGLDMQGKKAKASLE NVTKFRNSLSKLGDVYVNDAFGTAHRAHSSMVGCELEQRASGFLLKKELEYFAKALDNPN RPFLAILGGAKVADKIQLIENLLDKVNEMIIAGGMAFTFLKVLEDMEIGTSLFDSDGAKI VKKLMEIAEKNKVTIHLPVDFITGDKFSEDATVDTATLISGISAGEMGLDIGLKTRAQFS EVIGRAKTIVWNGPPGVFEFPNFSDGTKEMMKAVVAATQDGATTIIGGGDTATCAAKYNT ESKVSHVSTGGGASLELLEGKTLPGVAALSNA-SGIPSKSWKPAQVTLDTTMGKIIVELY WKHAANTCRNFAELSRRGYYDGVKFHRIVKDFVIQGGDPTGTGRGGASIYGKHFEDEINR ELKHTGAGILSMANSGPDTNGSQFFITLGPTQWLDNKHSIFGRVYSGMSVVHRIGMVETD QNDKPVDDIKIVRKRSRSRERKRSKSHSKRKKPYKYWDIPPAGFEHMSVPQYKAMQAAIP FAGSTISRQARRLYVGNIPFGVTEEAMMDFFNGQMKLTGLAQADGNPVIAVQINLDKNFA FLEYRSVDETTQAMAFDGINFQGQSLKIRRPRDYQPLPGLSEQPSIGVVSTVVQDSPHKI FIGGLPNYLNEDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDQACAGLNGMQLG DKKLIVQRASVGAKNGQ-LPVQLQVPGLDLQ--PTEVLCLMNMILAEELEDEEEYEDIVE DVKEECGKYGVVRSLEVPRPIRGVDVPGLGKIFVEFNSIIDCQKAQQALAGRKFSQRVVV TSYYDPEKYHRREFFFPLFDRVLVERFVPEVKTKGGIMIPEKAQGKVVEATVMAVGPGAV KDNGQVKPVSVKVGDKVLLPEYGGTKVTIEDSEYYLFRDGDLLGKFERLKTQIPDIKTSL DIVKHLLERKDPLETRFLLSDQVYAKAKIPPTDKVCLWLGANVMLEYNLDDAQKLLEKNT AKKTLGQVDDDLSFLRDQTTTLEVNMARVYNWDVKRRQK---MADEALANAGLHFDELNK IRVLEPEVSQQTTELKEECKDFVEKIGDFQKIVGTFIGVVDNVAKEVEKEKMKAIGARNL LKSIAKQREAHQQQLHALIIEKKMQLERLRIQHDALNKEESEQNDFLDQLILQK------ -----------------ELSPEEKDARTVFCMQLSARIRPRDLEEFFSSVGKVRDVRLIT DNKTRRSKGIAYIEFQQADSVPLAIGLSGQKLLGVPIIVQASQAEKNRTASAKGPMRLYV GSLHYNITEEMLRGIFSPFGKIDDIKLIKDHESGRSQGYGFVTFPEAEDAKKAYEQLNGF ELAGRPMKVGHVTERMAEGSMLDGEEIDRSGIDLGATGRLQLMAKLAEGTGFQIPQYAAN ALTQAGAQSAPPIATQCFMLSNMFDPLTTRLNWDQEIRDDVIEECSKHGGVLHIFVDKAS RQGNVYVKNPTIAAAVASVNALHGRYFAGRIITAAYVPVPNYHALFPESVRANQLIVPSS -EREDDVSITPPHPMKPRTRRGAVSAEVYKEEDAAQYVKKVVPKDYKTMAALSKAISKNV LFAHLDDNERSDIFDAMFPVHRHAGEVIIQQGDEGDNFYVIDQGDVDIYVNNDHVSTIGE GASFGELALIYGTPRAATVKAKNDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLTKVSIL ENLDKWERLTVSDALEPVQFEEGQVIVTQGEPGEDFFIILEGTAAVLQRRSENEEPVEVG RLGTSDYFGEIALLLDRPRAATVVARSQLKCVKLDRARFERVLGPCGDILKRNISQYNSY VSLSVAQYTGLAKLHRLMFVADHALSYSMTTYNANLYQVIHQKTQEAITANTPALDTQWI ETTAKKAALKLEKLDTDLKNYKSNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDY CTNPKHVVNMCLNVIKVSVYLQNWSHVQSYVNKAEATPEATEGKNGGQAIQTKLKCAAGL ADLATCKYKSAAKYFLQSSFDHCDFPELISPSNVTTYGSLCALATFDRQELQKNVITSST FKQFLELEPQLRDILHRFHESKYASCLKLLGEIKDNLLLDMYLAPHINTLYTQIRNRALC QYFSPYLSADMRKMASAFNTTLPALEDELMQLILEGQIKARIDSHNKILYAKDIDERSRT FEKAVAMGKEYQRRSKALVLRSAVIRNQIHVKSPPREAGQGGEMSIAPGTASSMPKQNEL MDKAEDVADQILRHSKHVLPHVARFCLISTFLEDGIRMWSQWGEQRDYMNSSWGCGWFLA SLFVFINLIGQLGGCVMVLSRQKVTIACGILFGIIALQTVAYSILWDLKFLLRNLALAGG VLLLLAENKAEGKSLFAGLPSLGENNPKQYMQLSGRILLVLMFLTLIRFEMNFFMLLQNI IGTVLILAIAVGFKTKLSALILVVWLTCLNFYFNAFWSIPDYKPMRDFLKYDFFQTLSVI GGLLLVVAYGPGGVSMDEHKKRW-----MVPGDGVGPDLMSSVQDVFQAAGVPVDFEEIF ISRNGAGLKGIITTPLRTLNMRIRRELDLFANVVRIKSLPGFKTKHNNLDFVIIREQTEG EYSALEHESVSGVIECLKIVTEEKSRRIAKFAFDYAMRLNRKKVTAVHKANIMKLGDGLF LKCCEEVAALYPHIEYEAMIIDNCCMQLVSNPHQFDVMVMPNLYGNIVDNLAAGLVGGAG VVPGESYSHDVAVFEQGARHAYAEAVGKNIANPTATLLGACNMLKHIHLEYHSKLIEDAV HRVVKAGKVRTQDMGGYASTSDFTHAVVNSL--EFNVFFTKTTRIVERALAENYDILVDY SGGDGENDVLAGERLKLNRTFYDDRWSRHRTVTSLDWSIQHPELIVASYNVNEDSPHDPD GIALIWNTKFKKTTPEYIFHCQSALMSTCFAKFHPNLVVGGTYSGQIVLWDNRVNKRTPI QRTPLSAAAHTHPVYCVNVVGTQNAHNLISVSTDGKMCSWSLDMLSQPQDSMELQHKQSK VAVTSFCFLSGDVNNFVVGAEDCTVYTACRHGSKAGINDSFDGHQGPITAVDCNSVQGQI DFSPYFLTSSFDWTIKLWSIKDQKFIHSFEDNSDYVYGVEWSPIHPALFASVDGNGRLDL WHLNNETEVPTASTVNVALNTCRWHQSGHMISVGDDMGKIHTYDVGEHLANPKPQEWSKF VHTLTELKQHAVEREDD-LEQHLLQATQAMEQQVDAEIEKMSKMDEDDFDALRQKRMDMM KKSAQQKQEWLAQGHGEYTEIANEKEFFDECKKSKKVVCHFFRDSTFRCKIVDKHLYLLA PKHLETRFLKINVEKAPFLVERLRIKVLPTICVAKNGKTTDYIVGFNDLGNKDDFSTEML EWRLGTADAINYSGDLLHPPLD--------------KSIVLSGFGGIKMLKVQPNPTVNE GEVLIRVKAGGLNFPDLMVRQGVIENAPKTPIIMGFECSGVVEALGENTTGLNVGDRVIG FSKCWADLVTCVYKMPDKMSFHEGAAVPMNFITAYILLFDIGNLRKDQSILIHSIGGGVG TALSQLCKTVDNVTVFGTASNKHENIKEN-VTHLYDH-STDYSQEVRKVYPQGVDIVLDC LCGDDTNKGISLLKPMGKYILYGSSNIVTGETKSFFSFAKSWWQVDKVSPIKLFDENKTI GGFQLRRLLVMDKLLNLYKENKIKPTIDSVWAFEDVGEAMQKMHDRKNIGKLILDPTAMS NKQTPSDFLKQIIGRPVVVKLNSGVDYRGVLACLDGYMNIALEQTEEYVNGQLKNKYGDA FIRGNNVLYISTQKRR-MAQDQSSLLLRKQLKELNKHPVEGFSAGLIDDDDLYKWEVVIL GPGDTIYEGGVFKAELTFPKEYPHRPPKMKFVTEMFHPNIGPDGSVCISILHEPGDDKYG YEKASERWLPVHTVETILLSVISMLADPNDESPANVDAAKLRREEPDVYKRKVGRLVRKS QD-------------------------------IQVNHVEDLELLIHPEGVLPVITFLKD HHTAQFLTITDIAGVDVPTRECRFEIVYQFLSIHFNARIRVKTYTDELTPIDSICSVFEG ANWYEREIWDMYGVFFANHPDLRRILTDYGFEGHPFRKDFPLSGYVEVRYDEEVQRVVIE PIEMTQEFRKFEYNTPWESFPTFRASLNPYCQIDYRAKMWACNFCYQRNPFPPQYSAISE QCQPAEIIPQFSTLEYTITRASCSPPIFLIVLDTCMEEEDLQALKESLQMSLSLLPPNAL IGLITYGKMVQVHELGSEGVSKSYVFRGTKDLNAKQIQDMLGIGRGAAQLPSNRFLQPVH KCDMSLTDLLGELQRDPWPVSQGKRPLRSTGVALSIAVGLLECTFPNTGARIMLFAGGSC TQGPGMVVGDELKHPIRSHHDIEKDNCKYMKKAMKHYEALSNRAANNGHVIDIYSCALDQ TGLHEMKFCPKYTGGHLVMGDSFNTSLFKQTFQRVFSKDSKGEFKMAFGATVEVKCSREV KVSGAMGPLVSLGVGPAVSDTEIGLGGTCQWKLCGLYPNTSLGLFFEVVNQHNAPIPQGG RGYVQFITQYQHSSGQRRVRVTTIARNWADASTSLQHIAAGFDQEAAAVLMSRLAVYRAE TDDGPDVLRWLDRMLIRLCQKFGDYNKDDPNSFRFSENFSLYPQFMFHLRRSQFLQVFNN SPDETSYYRHMLNTEDLTQSLIMIQPILYAYSFHGPPEPVLLDSSSITADRILLMDTFFQ IVIYHGETIHEWRKQGYHDLPEYENFKQLLQAPVDDAQEILQTRFPMPRYIVTEWDGSQA RFLLSKVNPSQTHNNMYGDSGAPVLTDDVSLQVFMDHLKKLAASSSS-----SEAQLKLA TDLELEMMADMYNRMTNVCQKKCIPAKYKEPDLSKGEAVCIDRCVAKYLEIHDRIGKKLT TLSQQDEATMKKLQETQQPAVIHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYR KKVILDGEEVQIDILDDYAAIRDNYFRCGEGFLCVFSITEQESFQATADFREQILRVKND ENIPFLLVGNKMDLDAKRQVSSEEASRRAAEWKVNYVETSAKTRANVDKVFFDLQREIRS RKMEKDRSKKKCVILKLYTGLRVVVTDHLINKVRDDVLAALNNNFLQTLNSAWNDHQTSM VMIRDILMYMDRVYVQQNNVDNVYNLGLIIFRDQVVRNPIIRDHLQTTLLEMVAKERRGE VVDRGAVKNACQMLMVLGIDSRCVYEEDFERPFLEQSAEFFRMESQKFLAENSASVYIKK VEARINEEAERASHYLDKSTEEPIVKVLEDELIGKHMKTIVEMENSGVVHMLENNKTDDL ACMYKLCVRVANGLKTMCNCISKYLREQGKALVVEEEEAKNAITYIQSLLDLKDRFGHFL HESFSDDKLFKQMISGDFEYFINLNAKSPEYLSLFIDDKLKKGVKGMTEQEIENVLDKSM VLFRYLQEKDVFERYYKHHLARRLLLNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFKD MTVSNTINEEFKLFVQQQVNLSGVDLTVRVLTTGFWPTQSATPRSSIPSAAQTAFEAFRR FYLAKHSGRQLTLQPQLGSADLHATFYGPKKDEGESAKNPRKHILQVSTYQMCILMLFNN REKWTFEEIKNHTDIPERELTRALQSLAVGKLAQRILHKDPKTKEIEAGHIFTVNDQFTS KLFRVRIQMVATKGEAEPERKETRNKVDEDRKHEIEAALVRIMKARKKLQHNVLIAECTE MLKPRFLPSPVVIKKRIEGLIEREYLARSADDRKVYTYVADKINVFPSRMALTIMKARLK GAQKGHSLLKKKADALTLRFRNILKKIIETKMLMGDVMKTASFSLAEAKFATGDLNHMIL QNVTKAQIKVKSKKENVAGVNLPIFEHYQDGADTYELTGLSRGGQQIDRLKKNYAKAIQL LVELASLQTSFVTLDEVIKITNRRVNAIEHVIIPRIERTLSYISTELDEREREEFYRLKK VQEKKKALR--------------PVKVLVTGAAGQIAYSLLYSIAKGDVFGDKQPISLVL LDIEPMMAVLDGVVMELQDCALPLLADVIPTADEAAAFKDIDVALLVGAQPRRQGMERKD LLKANVKIFKSQGAALDAHAKKTVKVVVVGNPANTNALVISKFAPSIPKENFSCLTRLDQ NRAQAQVASKENVQRTIIWGNHSSTQFPDLAHAVVAQEAIKDDNWVKNDFIKTVQTRGGA VIQARKLSSAMSAAKAICDHVRDWWFGTGE-RWVSMGIISKGYGIQQGLMYSFPVQIDKV VQVVPGLTISDFAREKMDATQAELVEERDCA---------VLMVGPNFRVGKKIGCGNFG ELRLGKNLYNNEHVAIKLEPMKSRAPQLHLEYRFYKQLGQSEGVPQVYYFGPCGKYNALV LELLGPSLEDLFDLCDRKFSLRTVLMLAIQLITRMEYVHSKHLIYRDVKPENFLIGRQST KKQHITHIIDFGLAKEYIDPETNKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEAL GHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEELATYLRYVRRLD FFETPDYDYLRKLFSELMEKMNYDCDWQFDWVGRQVRHGGSVQVVSSTNGDLAPTAAQSN TPITAQPEVEVVDETKRCMTTIRPFTCDDLFRFNNVNLDPLTETYGLPFYMQYLAHWPEY FQIAESPDGQIMGYIMGKAEGSGEMWHGHVTALTVAPEFRRLGLAAKLMQNLENISEKKQ CYFVDLFVRVSNQVAVEMYKKLEYSVYRRVLEYYSGDVDEDAFDMRKALPRDVDKKSIIP LKHPVRPEELERQLDCALDLMRRLPPQQIEKNLSDLIDLVPALCEDLLSSVDQPLKIARD KTVGKDYLLCDYNRDGDSYRSPWSNSYDPPLEDGAMPSDRLRNLEVEANNAFDQYREMYF EGGVSSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVIEVQEKSSGKSAHYKLTST IMLWLQTNKEGSGTMNLGGSLTRQVESDASVSEASPHIVNIGKMVEEMENKNRTVLNEIY FGKTKDIVNSLRSFNTLKGAALQKDLVAALAKRSQFDDGPDDLDESLGEMGEGENIEVLT GEAQVEPSKRITTRYMTKYERARVLGTRALQIAMCAPVMVELEGETDPLQIAMKEMKARK IPFIIRRYLPDGSFEDWALDELII--KRRSIKDIAMAPAGDSAFSLGQGVVAGSAVFGLG ALCYYGLGMSSEVGAIDRAALWPKVVKARIRDTYMYFGGSIALSALWRSPQAMSLMMRRP MLTFGAQIVGLIGAGMVCRSMEYTGGAKHLVWMAYSGIVGTTLAPLAVLGGPLLIRAAWY TAGIVGGLSAVAMCAPSEKFLNMGGPLAIGLGVVFASSIGGMFLPPTTALGAGLYSITMY GGLVLFSAFLLYDTQKIIKKAETHPTYGVRRYDPINGCLGIYMDTINIFIRLAILLSGGG GRRKMEIVYVYTKKRSEFGRQCNFSDRPAELHVDIVPDASLSQDFVERNPVDTAIQCVQE MSEHEVNTERFETSSRGINHTEGGWPKDVNPQEVEQVTRYRKKVEKDEMYIATIQQLGNI MEHCIKQNNAIDIYEEYFEDVDVDHIDETPSAKTINVFRDPNEIKRTATHISWFPDGPRK LAVAYCNLEFQGSSPDTMDSYIWDVENPNKPEMTLKPVSPLVCLEYNPKDSHILLGGCYN GQIAYWDTRKGSQPVEMTPIEQSHRDPAYKAIWIQSKTGSECFSTSTDGQVLWWDIRKLG EPTEKLYLD--KKQDFSKAQGAYSLEYEPTIPTKFMVGTEQGTVMSCNRKAKTPLEKIVA LYPGHIGPVYSLQRNPYFPKNFLSVGDWTARIWSEDIRESSIMWTKQYSSYLTDGCWSPT RPAVFFITKMDGTLDVWDILFKQNDPTLSLQVCDGPLHSLRVQEQAKLVACGSQDGTTTL LELSEGLYQLQRNEKNLVTAMLERETRREKILEGRHREMKLKERTKSSYEEKMENIMAIA NPIASKKLTKRIYKTVKKAVIRGIKQIQKFIKKGTKGFVVIAGDVHPIDAVSHLPILCED AEVPYCYIPSKQDLGRSLGSQY-CVVVMVQSHEDYEELYDETISEIKSLPLP-MPIENLE EEGLAKNPNLEYAQWKYLLGTEKYKNDKALAKKLQDAIKADSMAKFYEEVCKDLGWKLDA KLFKDMQTANEAEVKKLDQEIEDTEKNMGETEIRDSMLKKAEFLCKVGDKEAALSQFRKT YEKTVSLGYRLDLVFHLIRLGLFYMDHDLITKNLEKAQSLIDEGGDWDRRNRLKVYRGAY CMSIREFKTAANLFLDTVATFTSYELMDYHQFVTYTVISSVIALDRPDLREKVVKGSEIL EVLHSLPKIRHYLFSIYDCRYEEFFRSLAEIEELMKDDRLIVAHYRYYVREMRIMAYAQL LESYRSLTLEYMAKAFGVTVSFIDQELARFIAAGRLHCKIDKVGGIVETNRPDSKNWQYQ STIKQGDILLNRVQKLSRVINIIQGLKTSSKPVVGTPYNNITIGIAKESFPNEKRVAAVP AAVQNLKKGFNVNVEENAGVEAKFKNDDYAAAGANISTKDLFHSDIVLKVRGPSMEEVSQ FKDGGTLISFLYPAQNKDLVDKLGERRMTAFAMDCVPRISRAQVFDALSSMANIAGYKAV LEAANNFPRFFAGQITAAGKVPPAKVLVIGGGVAGLSAIGTAKNLGAIVRGFDTRAAVKE QVESFGAEFLEVNIKESGEGTGGYAKTMSKEFIEAEMALFAKQCKEIDILITTALIPGKP APKLISKQMIESMKPGSVVVDLASEAGGNIETIKPGELYRYNDVVHIGYTDFPSRLPTQS STLYGNNISKFLLSIGYNVNLEDEVVRGSIILHEGKLMWPPPAPPPPNYFNMTMKSAGKY SAGFGTIVGCGMISPNPQFTTMVTTFGLSGIVGYYTVWGVTPALHSPLMSVTNAISGITA AGGLLLMGGGYFPSNTIHGLAAAAAFISSINIGGGFVVTQRMLDMFKRADDPPEYNKLYG IPAAVFLGGYGYASTGAYPDIHQMIYLGAGLSCVGALTGLSSQKTARVGNVLGMIGVGSG VTATLGIIKPDLDTLVQMSTCMGLGGLIGGLAAKRIEVTDLPQMVALFHSLVGAAAVLTC FSNHLLEQPHFATDPAAGVLKGALFAGTFIGGVTFTGSLIAFGKLQGVLKSDPLLLPGRN ALNAGMGLSSVAALGTYMVSEDSTLLGMLGVTTTLSSILGVTLTAAIGGADMPVVITVLN SYSGWALCAEGFMLNNNLMTIVGAMIGSSGAILSYIMCVAMNRSIFNVILGGYGTSSTGK GKPMEITGTHTEVNVDDAVEMINEAKNIIIVPGYGLCVAKAQYPIAEMVSTLVKKGHNVR FGIHPVAGRMPGQLNVLLAEAGVPYDIVQEMDELNDDFPQTDLALVIGANDTVNSAAEED PNSIIAGMPVLRVWLANQVIVMKRTLGVGYAAVDNPIFFKENTSMLLGDAKKTCDALLTK IK----------PPGLQYLTQVDQLMVKQKLEAIEAVTGFETNNKYEITNSMGQRIYQAV EDTCCCTRNCCGASRPFDIKILDNTRKQVIHLSRPLRC--STCWCPCCLQKVTVEAPPGK TVGYVRQACCKPKFKINDAILRIKGPCCQWN--IC-GDIDFDVTSTDVGRISKQWTGLAK EMFTDADNFGMSFPLDLDVKIKSVMLGAVFLIDFMFFEKDKD--DPEMKKSLETEVQKNQ LRSQFLKLTDACWDTCMDKPRDKLDSRTEGCFINCVDRFVDTNQTVVSRFANMVQQ---- -------------KVEDHDSKETRLTLMEEVLLLGLKDREGYTSFWNDCISSGLRGCILI ELALRGRIELEKAGMRRRSLVNRKVICKSDTPTGDVLLDEALKHIKETQPPETVQCWIEY LSGETWNPLKLRYQLRNVRERLAKNLVEKGVCTTEKQNFLLFDMTTHPLTDSTFKQRLIK KVQDSVLTRWTNDAHRMDKRILSLIYLAHASDVLENAFAPLSDDDYEVAMKRVRELLDLE FDNETMKDGTNELMWAVISTINK-------------VCLKTLKKFKTLFEDTENLFRKFC KNLKGKEERFCYYVGGVETSATGILNKISDPIKNHLPESLICEKLKKADSQICDLKYDKS IDFATVKLNKLKVKDLKKILDNWGEACKGCAEKSDFVKKIEELLPKY--------IMSGF SLNWMNLRDADSGKILWQSSDDLAVPDAEHEARVPKKILKCRAVSRELNFSSKEAMEKFR LEQRVLFKGKCLEDWFFEFGFVIPGSTNTWQSVIEAAPESQMMPASILNGNVLIETRFFD GDLLVSTSKVRIFYVMPKVVSKSVVCTDTKDQEEYQGEKPLYVYYCICGQMSLILDCPME KLPLRKRDGARVIDGQKHANKLNCEPDNIIYLRRPEGIEKQYRQKCKRCGLFICYHHQSN IIFVVDGALKLESEVKKDIYTQLAKPQKVTLTKHTKNMGKFSSVTVSTIDEEEDEMEAKE IADSYAANAKVIEKQLLRKGMNKRKLLEQAEEESKR-RPKGTLID--------------- ----MSFTFASPSNVEVKQVDVPGITSMMGIFANHVPCLSVLKPGVVTVTESDSVVKRFF VSSGSVTINDDSSVQVLAEEAHPLENFDAGAVRDGLAKAQSAMSTEQQKAEAQIAVECYE ALSKAI-CRILAEELQLRLDETGKSKEVIETGHGLDTKKKKKYNFSELRLIEALQEPNIC DRILEYSVHKEKTGIERFAKGRSQTMEALHGLVNKGVKVELGMPHEMWDKPSVEITQMQR KCYALVEEYDEDIEDWYYNHQQPFLDYFC----------VFAATDVTSENDVVNALIAKS KFGGLDTVVNCAGIGIAKTVYDFKRNKPHSLEDFKRILEVNVGGTFNVTRLAVGLINANE PNSNGQKGVIINTASVAAFDGQRGQAAYAASKGAITSMALPLARDLGRQGIRVMTIAPGL FKTPLLESLPEAAIQQLCSYIPFPSRLGHPDEYAHLVQTIIENPMLNGEVIRLDGALRSR DFSFRVNGRNNSPNSQISRDYPVIDHTYDAVVVGAGGAGLRAAFGLANEGFKTACITKLF PTRSHTVAAQGGINAALGHMEEDDWKYHFYDTVKGSDWLGDQDAIQYMCEEAPKAVIELE NYGMPFSRLENGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLKYDTN YFIEYFALDLIMEDGECRGVIALCLEDGSIHRFKSKNTILATGGYGRAYFSCTSAHTCTG DGTAMVNRAGLANEDMEFIQFHPTGIYGAGCLITEGSRGEGGYLINSEGERFMERYAPTA KDLASRDVVSRSSTIEIREGRGCGPEKDHVLLQLHHLPPEVLHTRLPGISETAMIFAGVD VTRDPIPVLPTVHYNMGGTPTNYKGQVIKYEGGDEVVPGLYACGEAACASVHGANRLGAN SLLDLVVFGRACANTIAAENKPGESIGNVKQNAGEESVSNLDKIRHANGSTPTADLRLNM QKTMQNYAAVFRDGVTLKEGCDKMDGLFKQMDLKVHDRGLIWNTDLVETLELQNLMINAI QTIYSAENRTESRGAHSREDFKHRIDEYDYSKPVEGQTPKPYDEHWRKHTLSYVD-GDGK VKLDYRPVIDDTLDQNECPMVPPAIRSYMTALTQDEIVSNTKTVIQGLETLKNEHHQILN SLLTSMKTIKKGDTNLVEEKTNILKKSSEMIDLGLGEAQVMMALANHLQHVEAEKQKLRA QVRRLCHENGWLRDELATAQQKLQTSEQKSAALEEEKKHLEFMNEMKKYDSMDPLGFPDD DEDGPQSAMAQAASGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKNSGHD HPDVATMLNILALVYRDQGKYKEAANLLNDALLIREKTLGVDHPAVAATLNNLAVLYGKR GKYKDAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEQYYQRALEIYE SKLGPDDPNVAKTKNNLASAYLKQGKYKQKMGAKYDTAAEAEVRQWIKELLDTGTFEVEK NLRNGETLMKLIKKIACDNIRIKVNPPTSHFKQMENIELFLKASNAYGVKQSSLFLTSDL FEGRNMAMVLATILQVGTEAQRHGFEGKTCGSKPTEKHRVVFTEEQLRAGDLQAGTNKLA SQTIGGVRHVADIKADDCLREGQGVIGLQSGNKFASQKGMSFGAVRHIADIRADDAIQEG QGVIGLQSGTNKCASQAGMVMGAVRHVSDIRADDAVQDGQGVIGLQSGTNKFASQSGMSF GAVRHIADIRADNAADGQGVIGLQSGTNKFASQKGMSFGAVRHVSDIRADDADGQGVIGL QSGTNQFASQKGMGMGAMRHISDIKVEDMDSKSAINLQYGNPSGANQSGMSFGGRRDIMA EKHNFGIQPVTCHTFNKDRSGLALLNSSEVKIYKKKWQPTSSLQEHGQRVTSIDWAANSN KIVTCGADRNAYVWPNLVILRINRAATFVKWSPNEKKFAVGSGARLISVSYYEEDNNWWV SKHIKKPIRSTVTCLDWHPNSVLIAAGSTDFKARVFSGYIKEYDPKPEACSWGSKMPWGA LMAEHSNGGGWVHSVSFSPSGDRLVWVGHDSSVNVVDASVKGNFLPFKSVTWVTENSLVA AGYDCNPTVFTYDDAKLTLINKLDQGTMSAMNRFKNFDTRATELKTQHQNTITEIGIYSG TKADCTKFSTSGVDGNIIIWDIKKELEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGL GKSTLINSLFLTDLYSTEFPGPSHRIKKTVKVDTTQVMLKENGVQLKLTTTDTPGFGDAV DNSNCWQPIIDYIDSKYEDYLTAESRVNRTGIPDNRVHCCLYFIAPTGHGLKPLDVEFMK RLHDKVNIIPLIAKADTLTPEECKDFKRTILSEIAEHKIKIYEFEDEEDSKIQKKLRDRV PFAVVGSNRVMESSGKRVRGRQYPWGVVEVENLEHNDFIALRNMLIRTHMQDLKDVTNNV HYENYRYGKLAPVQKDPLTQMAEEKRDHDLKMKKMEAEMEQVFEMKVKEKKNKLKESEAD LQKRAEQMKKSLEQQQKELDDKWRQFEKEKQDWE----MARRYDSRTTIFSPEGRLYQVE YAMEAIGHAGTCLGILANDGVLLAAERRNTNKLLDEVSFSEKIYKLYDDMACSVAGITAD ANVLTHDLRLIAQSFVMSYQEPIPCEQIVSSLCDIKQAYTQFGGKRPFGVSLLYMGWDRH YGFQLYQSDPSGNYGGWKATCIGNNSANAVSMLKQEYKEGETNLQEALALSIKVLSKTLD MTKLTPDKVELATLTRENGKTKIRVLGFPEVDKLITVYNEEQAKIEAEKKKEVNEAWQRL KSQSLTRQERLFGAHEIQRFNRDADETIAWIQEKDTVLSSDDYGRDLASVQALQRKHEGV ERDLAALEEKVTVLGSESKRLVETHPEQSSQIKNKQEEIDSNWAKLKSKGFDRKNRLDDS YNLHRFLADFRDLVSWIHDMKAIISADELAKDVAGAEALLERHQEHKGEIDAREDSFKST AEAGQRLVESNHYAADEAREKLQTLATEKKTLMELWEERRILYEQCMDLQLYIRDTEQAD AWMTKQEAFLANEDLGDSLDSVEALIKKHNDFEKSLAAQEEKIKGLDEFATKLIESEHYS ADDVDARRNQLLQRRSLLHERATKRRHQLEASLQWHIFERDCDETKGWINEKLKTASDES YLDPTNLTTKLQKHQNFESELDANKNRISTIKTTGQELIDNDHFAKRQITERVEEIERLW NTLLQQTEKKGNKLKQARNQQNFNRNVEDVDSWLRDIEGQIGSEDFGKDLTSVQNLQKKH QLIEADVQAHQDRIESLSHMANAFKDEDHFDSDTIVAKKVQLVERYQKIKAPMVDRQKKL DDAKRLQQFQRDIADEEDWIREKEPIAASTNRGRDLIGVQNLMKKHQALQAEIAGHEPRI NNVCQHGQAMIKEGHFASKNIDESVEQLNERWQQLKDKSLQRKQDLEDSLQAQQYFADAN EAESWMKEKEPIAANTDYGKDEDSSEALLKKHEAFMSDLEAYRSVIEGLREQASSCKQQE APVIDDIGTEKVVALYDYVEKSPREVSMKKGDVLTLLNSVNKDWWKVEVNDRQGFVPAAY VKKLDPSLSASRNNLMDEFTISVRQNQIETQYANLLDLGNQRRDKLGESSKAYQLVRAAA ELAAWITEKENSMIGGEVGEDLEQVEEMQKKYNDFQKDLKANEARLEELNSIADRLTAMG QTEAAEKIREQITQLNQRWVTLQQVSAERAQTLGSAFEVQRYHREVDETKDWINEKDQAL NNDNYGHDLASVQALQRKHDAMERDLAALGEKVIELDEMSKRLMQTHPDQAETIYEHQTE INEQWNNLTAKADNRKAKLLDALDLQRFLSDYRDLTSWINSMMALVSSDELAKDVTGAEA LLERHQEHRTEIDARAGTFQAFELLGQQLLQNQHYASDDVQNKLEELAKAREELEQAWIS RRKKLDQCFELQLFYRDCEQAESWMAAREAFLADTVDG-DNVETLIKKHEDFDRAINSQE EKINSLQEFAEQLVHSEHYDADAVNLKRDQVLDRWSKLKDDLIDNRSKLGEAQTLQQFSR DADEMENWLQEKVQIASDESYKDPTNIQSKHQKHQAFEAELAANSERLQSLLGTGQNLID HKQCAGSEDAVQNRLESLATQWEDLVSKTTEKGEKLKEANKQQTYNAGVKDIEFWLGEVE QMLASEDHGKDLASVQNLLKKHQLLEADITAHEDRIKDLNTQADQFVEAGIWDAENITDR KQTINERYDRIREFAVRRRGVLNEANTMHQFLRDIDDEEAWIKEKKLLVGSEDYGRDLTG VQNLRKKHKRLEAELVTHEPTIQGVQETGEQLIADSDIGASDIRARLDQLDKNWKELKSS AQDRGHKLEQSYAYQQFSANVEEEEAWISEKQHLLSGDDFGDTMAAVQGLIKKHEAFETD FQVHRDRCVEINKEGEKLIVEGNHNAENIKQKIGGLEEHLNNLDQVASKRKANLVDNSAF LQFIWKTDVVESWIADKETQVRSDDFGRDLSSVQTLLTKQETFDAGLSAFEKEGIQTITA LKDQLVQAKHTQTPTIEKRFNDVMARWQKLLQDSEARKQKLLLLQDQYRQIEDLYLTFAK KASAFNSWFENAEEDLTDPVRCNSIEEIKALREAHDQFKASLSAAQADFNQLAALDKQIK EFRVGPNPYTWFTMEALEDTWKNLQKIIKERDGDLAREEQRQQENDQLRQQFAKSANAFH GWLTETRSAMMEGSGTLEEQLEATKLKATEVRAQKGHLKKIEDLGASMEERLILDNRYTE HSTVGLAQQWDQLDQLCMRMQHNLEQQIAARNRSGVSEDALREFSMMFKHFDKDKSGKLD HQEFKSCLRALGYDLPMVEEGQVDPEFQAILDLVDPNRDGYVSLQEYMAFMISRETENVQ SSSEVEQAFRALTSGEKPYITAQELYANLTREQADYCIARMKPYVDKSGRTIADSYDYAD FTRQLFVNSIQCFQCDSNEDISCPNDEPFDTSVNAKVDCNSFEAHTPGQFCVKIVQESPG WRGWKKVTRRCGSRTDFGVAWGCRWSWDYTGVFRETCYCETSDGCN----IDANDKDNPQ LVSDYVNDIYQYMRKLEVDEVTGKMRSILIDWLCQVHHRFHLLQETLYLTVSIIDRFLQV PISRNKLQLVGVTSMLLASKYEEMYAPEVADFVYITDNAYTKADIRTMEQLILKTLNFSF GKPLCLHFLRRNSKAGQVDATKHTLAKYLMELTIVEYDMVHYNPSQIAAAALCLSMKVLD WCDTLAHYSAYTEKELTPLLQKLSQLVVKKLTAVRTKYLSSKFMKISTIPELKSSVITDL A----------------------------------------------------------- ---------------------ECDQVHIDDVSSDDNGQDLSNYNFATDGFHAAANNTLCL ATGVRGGVDWMRKLAFRYRRMKEIYNTYRNNVGGLLGTPKREQWLQLRQEIEQYTDNWLT TALRSLSIINSRTNCVNVLVTTTQLVPALAKVLLYGLGGVFDIDNIYSATKIGKESSFER IVSRYGRKCTYVVVGDGRDEETAAKQV-------------------------TTALTVGG DRTTGQSVRTQNVLAACSIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEH PAAKVLVELAELQDQEVGDGTTSVVIIASELLKNADELVKAKIHPTSIISGYRLACKEAV RYIQEHLVINVDDLGRDCIVNAAKTSMSSKIIGPDSEFFSNMVVDAATAVKTPDGKGGYR YPIKAVNILKAHGKSSRESRLVQGYALNCTVASQAMPKRIANPKIACLDFNLQKSKMHLG VQVLIEDPTKLDGVRQREMDITKERIEKILKAGANVILTTGGIDDLCLKYFVEAGAMAVR RCKKADLKRIAKATGAQFLMTLCNLEGEEVFDASMLGQAEEVLQERICDDELLLIKGPKT RSAASLILRGANDFMLDEMERSLHDALCVVKRVLESKSVVAGGGAVEAALSIYLENFATS LSSREQLAIAEFARSLLVIPKQLAVNAAQDATDLVAKLRAFHNKSQTKKDDNELRWVGLD LFEGVVRDNKKAGVLEPSISKIKSLKFATEAAITILRIDDLIKLVNPEQGGNSYAEALRS GQLEDPEARLLISKNVLNNFLVEGKDLTVEYKIFNVGGGPALDVHLKDSSFPAADFDVVR GNLDVTWERIGPGANVTHAVILQPTKYGYFNFTSAEVSYHSKEDEQRFGYTSAPGEGGIV NRKEFDRRFSPHVLDWLVFAVMTLPSLGIPCLLWYSSSRRF--------SGGSHKDVTEK YKSILELIPSLQVFVEALINENVSLVISRQILTEFTTQLTKLPDNIAKQVSHFTLEKIHS RVISFEEQVAAIRQHLADIYEHEQSWKEAAGVLVGIPLETGQKQYTTDYKLQTYLKIARL YLEDDDPVLAEAFINRASILQADSQNEELQIHYKACYARVLDYRRKFIEAAQRYNELSYK AIVADEERMTALKNALICSVLASAGQQRSRMLATLFKDERCQQLPAFNILEKMYLDRIIR GSDLQEFESLLQAHQKAITSDGSTILDRAIIEHNLLSASKLYNNISFSELGSLLEIKPAK AEKIASQMITEGRMNGYIDQIDSIVHFEARETLPTWDKQIQSLCFQVNNIIEKISTTAPE WTNK-------MRLTENVVRNLRVAKIFRENTERINSIDFSSNGETLISSSDDDSIVIYD CLNGTPKRTLNSKKYGVDLIRYTHAVNAALHSSTKVDDTIRYLSLHDNKYIRYFPGHTKK VVTLCMSPIDDSFLSGSLDKTIRLWDLRSQNCQGLMHLSGRPVASFDPEGLIFAAGINSE TVKLYDLRSFDRGPFAAFKLPQDKECDWTGVKFSPDGKLILISTNGGVLRLLDAFQGTPL QNFTGFTNNRGLPIEASFSPDSQFVFCGSTDGKVHSWSTETGTKLAILQADHPGPIQNLL FNPKYMMMASACSNMAFWLPLVDE-----EKKGNDQNVGFIQLNRPKALNALCDGLMKEI GQVLGEFEKDKTIGCIVLTGSERAFAAGADIKEMQHRQFSEVFSGNFLSHWNHVATSRKP VIAAVNGFALGGGCELAMMCDIIYAGEKAQFGQPEITLGTIPGAGGTQRLIRAVGKSKAM EMILTADRMNAQDALAAGLVSKVFPVDQLIPESIKQAEKIAQYSKLMVAMCKEAVNSANE LTLQEGLHLEKRLFHSTFATNDRKEGMTAFTEKRPPKFTD >Lumbricus_rubellus MTERKAVIKNADMSEDMQQDAVDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSGFLSQLRLFQTGSVVKDIDQAAKYIGAGAATV GVAGSGAGIGSVFGSLVIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLILFAFM SQYKDSGKAPEATVHRIRITLTSRNVKSLEKVCADLIRGAKDKQLKVKGPVRMPTKTLRI TTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADMDMVM QYVEPAKQFAKDSIRLVKRCTKPDRKEFQKIAVATAIGFAIMGFIGFFVKLIHIPINNII V-------KRKFVADGVFKAELNEFFTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVL GEKGRRIRELTAVVQKRFNFPEGTVELYAEKVATRGLCAIAQAESLRYKLIGGLAVRRAC YGVLRFIMESGAKGCEIIVSGKLRGQRAKSMKFLDGLMIHSGDPMNDFVDQAVRHVLLRQ GVLGIKIKIMLPWDPTGKIGPKKPLPDHVSILDPKDQAAPEQPWSEQKGAKMSKRGRGGS SGGKFRISLGLPVGAVINCADNTGAKNLYIISVHGIRGRLNRLPAAGCGDMVMATVKKGK PDLRKKVMPAVVIRQRKTIRRKDGLFIYFEDNAGVIVNNKGEMKGSAITGPVAKECADLW PRIASNASCIRKQKTVKVTLGPQVAEGENVFGVAHIFASFNDTFVHVTDLSGKETIVRVT GGMKVKADRDESSPYAAMLAAQDVAERCKTIGITALHIKVRATGGNRTKTPGPGAQSALR ALARAGMKIGRIEDVTPIPSDSTRRKGGRRGRRLMGKPRGLRTARKLKNHRREQRWHDKD YKKSHLGTRWKSNPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP RDGCLNFIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVASVSLLALYKQKKERPRSDAV ATIRTRKLLTNRLLCRKQMVVDVLHPGRATVPKTEIREKLARLYKTTADVVFCFGFKTQF GGGKTTGFALIYDTLDYAKKFEPKYRLARHGARKQRKERKNRQKKVRGTKKAKVGAMPRI ALVRSKTYSTPRRPFEKERLDQESKLIGEFGLRNKREVWRVKYTLTKIRTAARELLTLDE KDPRRLFEGNALLRRLVRIGVLDEQKMKLDYVLGLRLEDFLERRLQTQVLKLGLAKSIHH ARVLIRQRHIRVRKQVVNLPSFIVRLDSQKHIDFSLKSPYGGGRAGRVKRKNQRKATGGG DAMGNIFAKLFQNLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVGEAREELMRMLAEDELRD AVLLVFANKQDLPNAMNAAEITDKLGLHSLRQRNWYIQATCATSGDGLYEGLDWLSNQLK NQKMPLTRDLLHPTLKDEKRKCKLKRLVQSPNSFFMDVKCPGCYKITTVFSHAQTVVLCV GCNTVLCQPTGGKARLTEGCSFRRKQHMVRMNALADALKSICNAEKRGKRQVLIRPCSKV TVKFLTVMMKHGYIEDFEIIDDHRAGKIVINLTGRINKCGVISPRYDVKVKNIESWTTSL LPSRQFGFLVMTTSGGIMDHEEARRKHLGGKILGFFFMGRMHAPGKGISQSALPYRRSVP TWLKLGPDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQTRHVAGNKILRILKAKGLAPT IPEDLYFLIKKAVAIRKHLERNRKDKDSKFRLILVESRIHRLARYYKTRKVLPPVWKYES ATASALVAVVEAQDVKLFGKWSSDDVNVNDISLTDYIAIKDKYAKYLPHSAGRYQAKRFR KAQCPIVERLTDSLMMHGRNNGKKLMSMRIVKHSFEIIHLLTGENPLQILVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREASFRNIKSIAECLADELINASK GSSNSYAIKKKDELERVAKSNRMSEQMTLRGTLQGHGGWVTQIATTPQFPDMLLSASRDK KLILWRLTRDARYGYPQRALHGHGHFVSDVVLSSDGQFALSGSWDSTLRLWDLSTGQTTR RFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIDDCHTDWTSCVRFSPNT QNPIIVSCGWDRLVKVWNLTNCKLKTNHYGHTGFLNTVTVSPDGSLCASGGKDSQAMLWD LNEGKHLYTLDGGDTINALCFSPNRYWLCAATGPSIKIWDLEGKVVVDELKPEVISTS-K APDCLSLAWSSDGQTLFAGYTDKLIRVWQVSMAARMREYKLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKVVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTFNDLQDLREQILRVKDMDEVPMILVGNKCDLEDERVVGKLAKNWNCTFLETSAKSK INVTEIFHDLVRQINRKSPDTMGDEKK-SDEHINLKVTGQDGSVVHFKIKKNTPLRKLMS AYCERTGVKMGSMRFRFDGQPINETDTPSQLDMEDGDAIDVFQQQTGG-SALPLNPKPFL NGLTGKPVMVKLKWGMEYKGFLVSVDGYMNLQLANTEEYIDGALSGNLGEVLIRCNNVLY IRGVEDDDEDGEMREMSDVEGDDVAAAAVSTGPMDLNVAIQEVLKTALIHDGLARGLHEC TKALDKRQAHLCVLANNCDEQNYVRLIEALCAEHGINLIKVESNKKLGEWVGLCKLDKEG KARKVVGCSCVVVKDYGKESQALDVLNEYFKTRKXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------ENNAFVVDEVS TVIKEAVENAIGGGSYQPTKVAQWTSNIVEQCLNDLTALKKPFKYIVTCVIMQKTGAGLH TASSCFWDNTTDGSCTVRWENKTMYCIVSVFGLAMMYSTSAKIQKPEGEKVDELESSISQ ALLELEMNSDLKAQLRELVFTGAKEVDVQNRKAIIVYVPVPQLRAFQKIQPRLVREMEKK FSGKHVVIIAQRRILPKPTRKSKTKNKQKRPRSRTLTHVHDAILEDLCFPSEIVGKRIRV KLDGTRLIKVHLDKSQQTNVEHKLDTFAAVYKKLTGKDVTFEFPEYVLGRGGFRGGFGGR GRGRGRGRGRGKEGDKEWVPVTKLGRLVKDQKIKTIEEIYLFSLPIKEAEIIDYFLGTTL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDFNGHVGLGVKCSKEVATAIRGAITLAKLSI VPVRRGYWGNKIGKPHTVPCKVTGRCGSVLVRLIPAPRGTGIVSAPVPKKLLHMAGIDDC YTSASGQTATLGNFAMATYHAIANTYCYLTPDLWKETVFVKSPYQEHTDYLMKMSGGLDV LALREDDVTKFLSCHTHIGVAQLDFQMEQYVFKRRNDGVFIINLRRTWEKLLLAARAIAA IENPADVCVISARPYGQRAVLKFAHYTGATPIAGRFTPGTFTNQIQTAFREPRLLVITDP RTDHQPVREAAYVNVPVIALSNTDSPLRYIDIAIPCNNKGAHSVGLMWWLLAREVLRLRG TISRDMPWEVMVDLFFYRDPEETEKEDAVTDWATESTAAPAPVPTEDWSATDTGDWGATP AATEWGGMKFNKLVSSSSRKNRQRHFSAPSHIRRKIMSAPLSKELRQKYNVRSIPIRKDD EVQVVRGHHKGQQVGKVVQVYRKKYVIHIERIQREKVNGATSHVGIHPSKVVIVKLKMDK DRKAILERKAASRQKGKHTEESVSSPSSTSVGSAVRQRKTATSSAASAGMWRFYTEDSPG IKVGPVPVLVMSLLFIASVFMLHIWGKYTR-KKEMKKKSVTNEVVTREHTINLHKRIHGV GFKKRAPRAIGEIRRFAEKAMGTPDVRIEARLNKHIWSQGIRNVPFRVRVRLARKRNEDE DSPNKLYTLVSYVPVTSFKGSQTVNVESXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNADKLKHRIGGKGTARRKKKVIPRSTAAD DKKIQMAVKKIGVNAIPGIEEVNLFKDNGEVICFNNPKVQACLQSNTFVVTGHAETKQIT DILPSLLSQLRGESLASLGSLSS--VEID-EDDEVPDLVENFDEASKTEMTRYSLPPENP AKSALARGSHLRVHFKNTRETAQVIKHMHLRRAVAFLKNVIAHKECVPYRRFTGGVGRCA QAKQWGATQGRWPKKSAEFLLQMLKNAESNAEFKGLDTDHLVIDHIQVNRAPKMRRRTYR AHGRITPYMSSPCHIEIILSEKEQAIAKPEKKKVSQKKLKKQKMMMREXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXMGISRDKWHKRRKTGGRMAQVRKKRKFELGRPAASTKIGA RRIHTIRTRGGNKKYRAMRLDTGNFSWGSEGVSRKTRIMDVVYNASNNELVRTKTLVKNA IVVIDAVPFRNWYEAHYALPLSRKKGAKLTPEEEARLNKRSKKAQRKYDTRKKTSKVETA LEEQFTSGRLLACVASRPGQCGRCDGYILEGKELEFYARKIKAKKGKMSLVLPEKFQHIL RVMNTNIEGKRKVPFALTAIKGVGRRYAHVVCKKANVDVTKRAGELSDEEVEKLITIMGN PRQYKIPDWFLNRQKDVKDGKFAQVMSNTLDSKIREDLERLKKIRTHRGLRHFWGLRVRG QHTKTTGRRGRTVGVSKKKDSATDSDAEDSVPELEEVAEAAGLAEELVSKAKQSRSEKKA RKAVSKLGLKQIQGVSRVTVRKSKSILFVINRPEVFKSPVSDTYIMFGEAKIEDLSQQAQ MAAAEKFK---------------------------------------------MGRVRTK TVKKASRVIIEKYYPRLTLDFHVNKRICEEIAIIPSKKLRNKIAGFVTHLMGRIQKGPVR GISIKLQEEERERRDNFVPEKSAIEEIDADTKEMLKAIDMEKIQNLQVIAPVANQMRWEY KEENPFEKRKAEGEKIRKKYPDRVPVIVEKAPKARVADLDKKKYLVPTDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGTLYQEHREEDFFLYVAYSDESVYGMRDLRILKL CLNICVGESGDRLTRAAKVLEQLTGQTPVYSKARFTVRSFGIRRNEKIAVHCTVRGAKAE EILDKGLKVREYELKRGNFSCTGNFGFGIQEHIDLGIKYDPNIGIYGMDYYVVLGRPGYS ISKRRRAHGSIGHKHRVTKEEAIKWFQQKYDGVILPGK---------------------- -------------------------------------------------NRGTLMESGIS PIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMVITVGQSIVYVMTGMYGAPAD IGAGVCLIIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFI------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------KTWIDV SGSSAKDVAKQLKEQQMVMAGHRDASMIRELNRYIPTAAAFGGLCIGALSVLADFLGAIG SGTGILLAVTIIYQYFEIFVKEQADMGSFGSMLFQTERAFQKQPTVFLNKKKAV-PRHVK SIGLGFKTPREAVDGHYIDKKCPFAGAVSIRGRILTGIVLKRKMQGTIVIRRDYLHYVPK YERFEKRHKNLSVHLSPCFRDVQAGDIVTVGECRPLSKTVRFNVIKATKGTGSKKGFQK- MVNVPKQRKTFCKGQKCRKHTLHKVTQYKKGKDSVFVQGKRRYDRKQSGYGGQTKPIFHK KAKTTKKIVLKMECTECKYKKQLAIKRCKHFELGGDKKKKGQMIQFMGRVIRSQRKGAGG IFKAHTKNRKGAAKLRAVDFAERHGFIKGVVKDIVHDPGRGAPLAKVVFRDPYRYKLRTE TFIAAEGMHTGQFLYCGKKANLQVGNVLPIGSMPEGTVICCVEEKTGDRGRLARTSGNYA TVIAHNVETKKTKIKLPSGTKTTIPSNNRAMVGIVAGGGRIDKPMLKAGRAYHKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGKASTVARDKSAGRKVGLIAARRTGRLRGTKQVTG KAKRTKKVGIVGKYGTRYGASLRKDIKKMEVTQHSKYTCSFCGKETMKRKVVGIWSCNKC KKIVAGGAYVYSTNAAVTIRSTIRRLKEA--MGRRPARCYRYCKNKPYPKSRFCRGVPDA KIRIFDLGRKRAKVDEFPLCIHLVSDEFEQISSEALEAGRICANKYLVKHCGKDAFHLRV RLHPFHIIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVDIGQVIMSVRAKDGHKEKVI EALRRAKFKYPGRQKIHVSRKWGFTKWDRENFEALRAENRLVPDGVSVQYKPDHGPLAAW YAA-KVTKILGRTGSQGQCTQVRVEFLDETSRSIIRNVKGPVREGDILTLLESEREARRL R------------------------------RRRCSRCGYPEKRMRKYNWSEKAKRRRTQ GVGRMQHLKKVYRRFRNGFREGTVAKKAVQMVEDRASAKELDQWIEQLMDCKQLSETQVK TLCEKAKEILTKESNVQEVKCPVTVCGDVHGQFHDLMELFKIGGKSPDTNYLFMGDYVDR GYHSVETVTLLVGLKVRFKDRITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDS------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MGAYKYIQEMFRKKQSDGMR FLLRIRCWNFRQLAAVHRASRPTRPDKARRLGYKAKQGFVVYRVRIRRGGRKRPVAKGQV YGKPKSCGVNQLKNQRSLQAVAEERVGRRCKALRVLNSYWVAEDSTYKYYEVICVDPFHK AIRRDPEIQWICKPVAKHREMRGLTSANRKSRGLGKGHGYSKTIGGSRRANWRRTNTVQM HRKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGKSSKMLQHINYRMRCTL QDGRTFIGTFKAFDKHMNVILGDCDEFRRVKPK-SKTREEKRALGLVLLRGESLVSMTVE GPPPPEDGIARVPIPGASGGPGMGRAAGRGVPS-HGLAGPARGVGVPPSQMMQPGPGMMR GPPPEDMPSFKLVLVGDGGTGKTTFVKRHLTGEFEKKYIATLGVEVHPLVFHTNXGPIRF NVWDTAGQEKFGGLRDGYYIQGQCAIIMFDVTARITYKNVPNWHRDLVRVCDNIPIVLCG NKVDVKDRKVKAKAIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLTGDPNLEFVAMPA LAPPEVEMDPTM-----------------------NEGIKQYYITKNEELQLIVADKTQN LRRLEAQRNELNAKVRLLREELQLLQESGSYVGEVVKAMDKKKVLVKVHPEGKFVVDIDK NIDINDVTPNCRVALRSDSYTLHKILPNKVDPLVSLMMVEKVPDSTYENVGGLDKQIKEI KEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIR-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----LGFGENFALSGAAAIISKTAAAPIERVKLLVQNQGEMLKTGRLDKPYSGVIDCTM RTFRNEGIIPFWRGNLANCIRYFPTQALNFAFKDKIKAMFVMNKSDSYTVKFGKNIASGG VAGAMSLVFVYSLDYCRTRLANDAKAGKKRQFNGMIDVYAKTIKSDGFVGLYRGFVISCV GIVVYRGCYFGFYDTLKPILLGDKASLMASFALGYIVTITSGLISYPIDTIRRRMMMTSG EAVKYKGSMDCAVTVIKSEGFMALMKGAGANILRGVAGAGVLSGFDKFKELYVKWRVXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX VQLPPKGNRILYKKNPPNKITAEEMSNLFGKYGPFPQIQREKTAKTKGTPFVVYKNIFDA KKAGNHLSGFNVGNQNFVVLFSQPNKQYKKTILQKK-------------------XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMQNDAGEYVDM YIPRKCSASNRIISAKDHASIQINLAEVDPSTGRMTGQNRTYAICGDIRRMGESDDCIIH LAKKDSMVPQMVRGPKKHLKRVNAPKHWMLDKLGGVFAPRPSCGPHKLRECLPLSIFLRN RLKYALTYDEAKRILNQRLIKVDGKIRSDKTYPAGFMDVVSIEKTNENFRIIYDVKGRFA IHRITAEEAKYKLCKVKKVQVGLKGVPSIVTGDGRTIRYPDPLIKVNDTVKIMSGREDEY DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSILVDGKKIKAQIWDTA GQERYRAITSAYYRGAVGALVVYDIAKHLTYENTERWLKELRDHADHNIVIMLVGNKSDL RHLRAVPTDEAK------------------------------------------------ ----------------------MTSTYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVR GDKIVVLGVEKKAVAKLQEDRTVRKIALLDDHVALAFAGLTADARILINRARIECQSHKL TVEDPVTLEYITRYIAQLKQKYTQSNGRRPFGLSTLIVGFDETPHLYQTDPSGTHFEWTA NAIGRSAKTVREFLEKNYTAEVANDDETIKLALKALLEVVQSGSKNMEVAIMRKKQPLSI LTTDQIDTYIRQIEQEKEDEAEKKKKKGGGHGGDKKDDKDKKKKYEPPIPTRVGKKKKKL KGPEAANKLPQVTPHTRCHLKLLKLERIKDYLLMEEEFIRNQEQLKPQEEKQEEERSKVD DLRGTPMSVGSLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDQLEPGCSVLLNHKVHAVV GVLSDDTDPMVTVMKLEKAPQETYADIGGLDQQIQEIKESVELPLTHPEYYEEMGI---- ----------------------------------LIQKYLGDGPKLVRELFRVAEEHAPS IVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSKGDVKVIMATNRIETLDPA LIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTLAEDVNLEDYIMAKDDLSGADIKAICT EAGLLALRERRMKVTNEDFKKAKENVLYRKNEGT-------------------------- ------------------------------------------------------IVAGTV TNKMAPALRKIYDQMPEPRWVISMGSCANGGGYYHYSYSVVRGCDRIIPVDVYVPGCPPT AEALLYAVLQLQKKIKRMKTVQMWYRKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMAPQKKTKK TIESINSRLALVMKSGKYVLGYQQTLKTLRQGKAKLVIIANNTPPLRKSEIEYYAMLAKT GVHHYNGNNLELGTGCGKLFRVTTLSITDPGDSDIIRSMPSGXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXMGDRYNIHSQLEHLQSKYIGTGHADTNKWEWL TNQHRDSYASYMGHPDLLNYFAIAENESKARVRFNLMERMLQPCGPPPEKPEDMKIDLCV FSGSKIYPGHGKKLVKIDGKSYHFANSKCAKLHLVKLNPRKINWTVLYRRKHKKGMTEEV TKKRTRRNTKFQRAITGASLNDIMAKRNQKPEVRQAQREQAIRAAKEKQKAKAKSQPRVG GKRMKLNISFPATGCQKLIEVDDERKLRAFYEKRMAAEVSAESLGDEWKGYVVRISGGND KQGFPMKQGVMTNGRVRLLLCDGHSCYRMRRDGERRRKSVRGCIVDANLSVLNLVILKKG EQEIPGLTDTTVPRRLGPKKASNIRKLFNLQKADDVRQYVVRRPLAPQTKAPKIQRLVTP VVLQRKRHRVALKKMRTVRKRESAAEYQKLLAQRLKEAKERKAERKRSASHSKKVKAKEL RGKKKDELLKQLDELKTELSQLRVAKVTGGAAAKLSKICTVRKSIARVLTVMSQAQKENL RKFYKPKDLRPKKTRALRRALTEHELSIKSVKFVRKQRAFPMRKFAVKDSPKGPKVTDKV YFDIEIGGEKAGRIVIGLFGKTVPKTVKNFKQLAEGTESYKGSKFHRVIKDFMIQGGDFT RGDGTGGKSVYFPDENFKLKHYGAGWISMANSGKDTNGSQFFITTKKTEWLDGRHVVFGL VLEGMSVVRQIENSEKDRDRPLKDAVIADSGSLAVDTPFAVPREPAKEKKKKTSQKFALD CAHPVEDGIMDLGNFEKFLLERIKVNGKVGNLKSKILVNSEIPFSKRYLKYLTKKYLKKN NLRDWLRVVANGKDSYELRYFQINNEEEDEAEDK-------DDSQYGGCEGPDAMYVKLI SSDGHEFIVKREHALTSGTIKAMLSGPGQFAENETNEINFREIPSHVLQKVCMYFTYKVR YTNSSTEIPEFPIAPEIALELLMAANFLDC-KVITFEELKQHKDEKSLWIAIYDNVYDIT KFAAEHPGGEEVLQDQAGKDGTAAFEDVGHSSDARDMMKQYQIGVLADSDRSSLLSWLFP VGLAILAVFLFRYFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSHVPLTLDMV QERVLLVLRLYDKINPEKLTMESHFTNDLGLDSLDHVEVIMAMEDEFGFEIPDSDAERLQ RPADIVQYIADKEDLERTVKTMPDDLKNVEFETSEDVDVTPAFDSMGLREDLLRGIYAYG FEKPSAIQQRAVKPVVKGRDVIAQAQSGTGKTATFSIAI--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------APMRRP FDPVVHDLDPNFRLTRFSDLKGGCKVSHDAMTKMLEPFKEQLEQEQVHFQFVAPSPRIGI GMDSCITPIRNGGLSLVQTASFLYPIIDDPYMLGKVTCSAVLSNMYAMGVTECDNMLMLL SISQKMTDKERDVVMPFIMSGFKDVAEETGTSVNGGQTIINPWMTIGGVATSICQPNEYI M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------VSSYFITIDAHAEECFFDRVTSGTKMSLMFEVAEGGFLDI DVHITGPDGKNIYSGERESNGKYTFAAHMDGIYKYCFSNKMSTMTPKIVMFSMDVGDKPK ATQNKLEEMINELSTALTGVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMT LGQVYYLKRFF---------TLQPYLKAVRQTLTAAICVENFSSQVVERHNKPEVEVRTS KELLLTPVTISRNEKEKVLIEGSINSLRISIAIKQADEIEKILCHKFMRFMMMRAENFII LRRKPVEGYDISFLITNFHTEQMYKHKIVDFIIHFMEEIDKEISEMKLAVNSRARISAEE FLKRFSRRKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEIMVDDRLV TLQIWDTAGQERFQSLGVAFYRGADCCILVCDVTTPTTFRSLDSWRDEFLIQS------- ------------------------------------------------------------ --------------------------TAPFDTRFPNQNQTRNCWQNYVDYHRCLKIDDYA PCEYFQKVFKSLCPNEWTSTWDDQRENGAFAGKI-------------------------- ------------------------------------------------------------ ------LQVARCTKIINADSEEPRYIINVKQFAKFVVGLGDQVAPTDIEEGMRVGVDRNK YQIHIPLPPKIDPSVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPMLHPEKFVNLGM DPPKGVLLFGPPGTGKTLCARA-------------------------------------- ------------------------------------------------------------ ----------------------------LQIHARSMSVEKDIRYDLLSRLCPNSTGADIH SVCTEAGMFAIRSRRKMATEKDFLEAVNKVIKQYAKFSSTAKYMAYNMGAEKIHINIVVI GHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITI DISLWKFETARYYVTIIDAPGHRDFIKNMITGTSQADCAVLVVAAGVGEFEAGISKNGQT REHALLAFTLGVKQLIVGVNKMDSTEPPYSETRFEEIKKEVSQYIKKIGYNPEAVPFVPI SGWHGDNMLKMAWFKGWSVYGGTTIMEALDNIDPPKRPTDKPLRLPLQDVYKIGGIGTVP VGRVETGIIKAGMIVTFAPVNLTTEVKSVEMHHQALEEAMPGDNVGFNVKNVSVKDIRRG NVAGDSKNDPPKETEEFKAQVIILNHPGQINAGYAPVVDCHTSHIACKFRELLEKIDRRS GKKLEDNPANVKSGDAAIVEMVPQKPMCVEAFADYAPLGRFAVRDMRQTVAVGVIKSVKK RDGGSGKVTKAAQKAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPKQ LLEIKDFLMTARRPDAKSVKIKKNTKFKLRCSRYLYTLCINDGEKADKLRQSLPPGLQVK DLKMSKISRDILLEAINSLLQKKRKFTESVELQISLKNYDTQKDKRFSGTVKLRHVPRPK MSVCVLGDQQHCDEAKANSIPCMDQDALKKLNKQKKPIKKLAKQYDAFLASDSLIKQIPR IVGPGLNKAGKFPSMLTHNESMVAKIEDVRATIKFQMKKVLCLAVAVGHVAMTPEELATN ITIAINFLVSLLKKNWQNVRALYIKSTMGPSQRLYXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXMTDPVIQNLQDPFAEDEGIHIRIQQRNGRKTLTTVQGVSSEFDFKKI VKVAKKEFACNGTVVEHPEYGEVIQLQGDQRQNISKFLKQVGLDDQIKVHGFXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------IGDRQTGXTAVAIDTFINQKRFNEGQNEKAKLYCIYVAIGQ KRSTVAQIVKRLTNADAMKYTIVVSATASDAAPLQYLAPYSGCAMGEFFRDNGRHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDTFGGGSLTALPIIE TQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQMRAMKQVAG SMKLELAQYREVAAFAQFGSDLDAATQQLLNRGVRLTELLKQGQYTPMAVEEQVSVIYAG VRGHLDKLDPSRITTFEREFLAHLRSSQQELLKTIREAGKITDETEALLKKVVTTFLSGF ----------------LRLRRPPWLKMPSGMVVFAAVLLSYFLVTGGIIYDVIVEPPSLG STTDERGNSRPVAFMQYRVNGQYIMEGLASSFLFTMGGLGFVILDQTNKPSTPRLNRILL LCVALVCVLVSFFMCRVFMRMKLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEYAQVTKMLGNG RLEATCFDGSKRLCHIRGKLRKKVWINGGDIILVGLRDYQDGKADVILKYTPDEARNLKA YGELPESAKINEEGDDNITFDDIDELLVRFLMKLSHETVTIELKNGTQVHGTITGVDVSM NTHLKSVKMTVKNKDPVQLETLSIRGNNLRYFILPDTLPLDTLLIDDAPKARGRGXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPLVIDAKDHLMG RLAATVAKTLLEGQRIVVVRCEEINISGNFYRNKQKYLDFLRKRMNTNPCRGPYHFRAPS KIFWRTVRGMLPHKQYRGKDAMERLKVYEGVPPPYDKIKRIIVPSALRVIRLKPRRKYCK LDRLASEVGWKASKVVGTLEKRRKLKAAIYYKKKKTENKLMEKARKNPQYQQIIEGFGY- -DATKGAQVFKQRCAQCHTVEKGGKHINGPNLHGLIGRQTGQAPGFSYTEANKKKGIKWT RDTLFEYLENPKKYIPGTKMIFAGLKSAPARSDLIAYLESATKXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXX-------------------------------------------- ------------------------------------------------------------ ----------------HADAPEFVEMSVEQEILETGIKVVDMLAPYAKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIMSGVIDLKGDKSKVSLVYG QMNEPPGARARVALTGLTVAEYFRDKEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPXPGTTFAHLDATTVLSRG-- ------------------------------------------------------------ ------------------------------------------------LDHLPEVAFYMV GPIEEVVTKAERLAEELMLMSKKNRVMIYEYLFKEGVLVAKKDFHLPKHGEIDVPNLHVI RAMQSLVSRGYVKEQFCWRHYYWYLQNEGIQYLRDFLHLPPEIVPATLKRQQVGEDRAGY RRG-GSDKKGEAGAGADXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXX----------SWFCGXRGNEFFCEIDEDYIQDKFNL TGLNEQVPHYRQAIDMILDLEPDDDLEDNPNQSDLIEQAAELLYGLIHARYIMTNRGIGQ MIEKWQQGDFGFCPRVYCENQPMLPIGLSDVPGEAMVKLYCPKCQDVYVPKSSRHHHTDG AYFGTGFPHMLFMVHPEYRPKRPANQFVARLYGFKMHPLAYELQYQAAASFKATYTNKK- MTNSKGYRRGTRHLFARKFRTHGVIPLSTYLKTYKKGDIVDIKGNGAIQKGMPHKVYHGR TGVVYNVTAHALGVIVNKRVRGRILEKRINVRVEHVKHSRCRQDFLDRVKANEVKKRDAK QIVHCKRQPQQPIPAHFVSTKYNKPVVLEPIPYEFIASNKSHYKVVAPDDPSMEWKDITD RAASKVFFLELAKGLGIVMSQLFKEPATINYPFEKGPLSPRFRGEHVLRRYASGEERCIA CKLCEAICPAQAITIEAETRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEY STETREELFYNKEKLL---------------------XXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXKKLTKQEEMLLQDFSRNVSTKSSALFYGNAFIVSAIPIWLFWR IHQMDLYIFFVVMTLVSSYLVAMAYKNVKFVLKHKIAIKRADAVSKEVMKKVADDKKMSK TEKEERILWKKNEVADYEATTFSIFYNNALFLMLVILASVYILRSLSPTINYSLSMAVAS GLLALFSTSSKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------FHMDPSGTFIQYDAKAIGSGSEGAQQSLQETYHKSMKLEDAC VEALRILKQVMEEKLNSTNIEMAKVTKKENFHMYNKKELEDVIAKLAKKTWELSNVVENV GIVDEIYRYDERQQRDILAAKPWEKDPHYFNSIKISALALLKMVMHARSGGNLEVMGLLL GKVDGNNMIVMDSFALPVEGTETRVNAQAQAYEYMAAYIEAAKQVQRLENAIGWYHSHPG YGCWLSGIDVGTQMLNQQFQEPFVAIVIDPIRTISAGKVNLGAFRTYPKGYKPPDEGPSE YQSIPLNKIXDFGVHCKQYYPLEVSYFKSSLDRKLLEMLWNKYWVNTLSSSSLLTNADYT TAQIFDLTDKLEQSEAYLGRSTLMHEKVEDRLTKATRDSCKNTIEAIHGLMSQVIKDKLF ---GGLPRRIIKETQRLKAEPVPGIEATPDESNARYFHVIVVGPKDSPYEGGVFKLELFL PEEYPMSAPKVRFMTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPD DPLANDVADQWKTNEAQAIETARQWTRRYAAENDELLDYDEEEQEEAKEVKGTYVSIHSS GFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVVCQAKSGMGKTAVFVLATLQ QLEPVDNQVSVLVMCHTRELAFQISKEYERFSKYMNSVKIAVFFGGMLIQKDETVLKTNC PHIVVGTPGRILALVKSLXLKHLKHFILDECDKMLDQLDMRRD----------------- ------------------PMEVYVDDNSKLTLHGLQQHYVKLKDNEKNRILIELLDALEF N----------------------------------------------------------- ----------------------------------------------------PASYADLG KAARDLFSKGFHFGQYKLEAKTKTSSGVEFTTSGSSAHESGAFAGSLETKYKWSEHGVTF TEKWNTDNVLQAEVSVEDQLVKGLKLSLDTNFAPQSGKKGGKVKTEYKHDYVHTN--LDL DLSSLNVFGSAVVGYKGWLAGYQLALDKSLLSQSNFAIGYSKDDLTLHTAIINGSEYQGT IFHKVNSRLESAVALSWTSGSHETRFAVGAKYNPDQDSTIRA------------------ -------------------------------NPRDKILQDYRKKLLETKELDAKLKETRE NLKELTKQYEKSENDLKALQSVGQIVGEVLKQLTEDKFIVKATNGPRYVVGCRRQLDKTK LKSGTRVALDMTTLTIMRYLPREVDPLVYNMSTEDPGNISYAQIGGLSEQIRELREVIEL PLMNPELFQRVGITPPKGCLLFGPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIGES ARLIREMFGFGRDHQPCIIFMDEIDAI--------------------------------- ------------------------------------------------------------ --------------------------------------------------------MPDN LKSVVKRFYDDYVQSTPKKLKIIDAYLLYILLTGIIQFVYCCLVGTFPFNSFLSGFISSV GAFVLAVCLRVQVNPQNKNEFQGISPERAFADFIFAHVVLHLVVINFIG----------- -----------HIIMKNDKEIVGTLLGFDDFVNMVLEDVTEFDNTPEGRRVTRLDRILLN GNNITMLVPGGEGPEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXMGKFMKNGKVVLVLGGRYAGRKAIIVKNYDDGSTDKPYGHALVA GISRYPRGVTKKMGKKKIKQRSKVKAFIKVYNYNHLLPTRYSVVEVDKRVVNKDIFKDGA LRKKANQEMKAKFEERYKSGKNRWFFQKLRFERTFIMAKPDAVHRGIVGDIIRRFEQKGF KLVAMKFMWASEDLLKKHYADLKDKPFFPHLVKYMSSGPVVPMVWEGNVVKTGRVMLGET DPFKSSPGTIRGDHAIEVGRNICHGSDAVESATKEINLWFNEKELVQWKPAQDDWVYEAA VPKPVKTPSKVKDKALKAKKAVQKGVNDKLARKIRTSVQFRRPRTLRLPRAPKYPRTSVP RRPQLDHHKIIKFPLTTESAMKKIEDNNTLVFIVDKTANKPQIKMAVKKLYSIQVSKVNT LIRPDGEKKAYVRLAPDYDALDVANKIGIIMAPKQKMRLANEKHSKNVVNRGNVPKSLKQ EDEKLPVGPWLLGLFIFVVCGSAIFQLIQSIRMVRIKEWTAVATWRWVANDENCGICRMP FDGCCPDCKLPGDDCPLVWGQCSHCFHIHCIVKWLNSQQVHQLCPMCRQEWKFKE----- ------------------------------------------------------------ ------------------VQNIVETFNEYFTKVTEVDIMVNMDRVYMILDEMIANGRIVE STQSRILAPLFVM------TIFGKIASGDIPTKFIYEDDQCVAFHDINPQAPIHVLIIPR KPIPQLSSDEQLLGHMLVVARKVGELSTGYRLVINDGRDGCQSVYHVHIHLLAGRQLGWP PXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXRLYVKAVFTGFKRGLRNQHENTALLKIEGVQKKIETDFYLGKKCCYVYRA KKKTACPGHDKPSHLRVIWGKITRPHGNSGAVRAKFRKNLPPKAMGRRIRVMLYXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPQNEYIDLHRKR QGRRFDYEERMRKKEARSAHERSAKAQKLRGIRAKLYNKQRHAEKIQMKKTIKMHDERKT KQKSENDDNKGVNSYFLLDREMQNQAKVLSNTIKQKRKEKAGKWNVPLPKVHAVSESDAF KVIKTGKTRRKAWKRMVTKACYVGEGFTRKPPKFERFIRPMGLRFNKANVTHPELKATFQ LPIIGVKKNPTSSLFTSLGVM--------------------------------------- -------MACRPLVTVYNEKGEATETLVKMPAVFQAPIRPDIVSSVHMDMMKNGRQPYAV SVKAGHQTSAESWGTGRAVARIPRVSGGGTNRSGQGAFGNMCRGGRMFAPTKTWRRWHRR INVNQRRYAICSAIAATGIPALVMSKGHCIEEIPELPLVLTDKVQEIKKTKEAVGVLRKL KAWREIEKVKSTRRYRAGKGKMRNRKRIQRRGPVIIYNQDNGITRAFRNIPGITLINVDR LNLLKIAPGGHVGRFCIWTESAFKKLDSIYGTWKKPSEQKTDYNLPMPIMTNCDLSRLLK SDEIQKALRPPKKDVPKRVLKRNPLKNIAVMSKLNPFAIVEKKQAKQKKKRQAALDAKRG IATVDSGGKSRPRKPVT--GYQDLASKILQIQSKRFYIDVKENRRGRFIKLSEVGVMGGK SRLVMDMATAADFHDKLTEFSEHYSALGPRSHREGEGDGKLKSEVIYSGDRRYYMDLKEN NRGRFLKVAPPSHDRSQIVIPAQGMIDIRDAFTDLLTEFGQENKPEEGGETAAASLQIDN KKFYFDVQDNRRGKYLRISEPNYRTAINIPFQSWDQFKELL--------KKAQDAKLKDA ITKKLIETGEREKLKELLRTRLIECGWKDQLKVHCKEIVRQRGLENITVDDLVAEITPKG RATVPDQVKKELLQRIRAFISQIS------------QNMQHCNLLCLPXNYQMKYYFYHG LSWPQLSYVAEDDKGKIVGYVLAKMEEDPEDSVPHGHITSLAVKRSHRRLGLAQKLMDQA SRAMVECFNAKYVSLHVRKSNRAALHLYKETLRFQISEVEPKYYADGEDAYAMRRDL--- ----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------------------- --------------TAFIGYKAGMTHVVREVDRPGSKVHKKEVVEAVTILETPPMIVVGL VGYIDTPKGLRTFKTVWAEHLSDECKRRFYKNWYCSKKKAFTKASLKWQDESGKKEIEKD LSKIKRYCSVVRILAHTQMKLMNRRQKKAHIMEIQLNGGSVPDKVEWAKTHLEKPIPVQQ VFDQDEMIDVIGVTKGKGFKGVTSRWHTRKLQRKTHKGLRKVACIGAWHPSRVSFSVARA GQKGYHHRTEINKKIYRIGQGVHTKDGRVVKNNASTEYDLTEKTITPMGGFPHYGVVNQD FIMLRGCCMGPKKRVITLRKSLLLQTKRKATEKVNLKFIDTSSKMGHGRFQTREEKQTFM GPLKKDMQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGRPINLG LWDTAGQEDYDRLRPLSYPQTDVFLICFSLISPASFENVRAKWYPEVSHHCPATPIVLVG TKLDLREDKETIERLRDKKLSPITYPQGLAMAKEIGAVKYLECSALTQKGLKTVFDEAIR AVLCPKPKPKKKKTCIVLIFDPNLKKKKKKKNTFDSDVLTADSHFDD-VLSKKKKKKKNM DMSDVSAALPKEDKHLTVKKKKEETDRDYTYEELLKRVFDIMREKNPDMVAGEKKRIIMK PPQVMRVGTKKSSFSNFVEICKMLHRQPKHLLAFLLAEL--------------------- ------------------------------------------------------------ --------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTIPETLKLRRKKKQT-NAAKKKLYFSLAE KYAKEYKHKEKDDIIKARQARKHNNFYVPQAAKVAFVIRIRGINGIAPKPRKVLQLLRLR QINNAVFIKLNKATINMLRLAEPYIAWGYPNLSITKKLLYKRGFAKVEGRRLPLS-NEII ERKLKK--LICVEDVIHELLTCGPLFQKASNMLWPFKLSSPNGGWRKKGRHYVDGGDFGN REEKINVLLKKMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSKAHPPELKKYM DKRLSLRLNGSRIVKGVLRGFDPFMNLVIDEAVEEGKNGEKNNIGMVVIRGNSVGLLEAL ERIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX----YDMAIGLKKGHKVTTTKPRPSRRKGALTKRARFVRDLVR EVTGFAPYEKRVQELLKVSKDKRALKFCKKRLGRTLRAKRKREEMSVVLQKMRKA-VDEV TKKQLAAIPLLKTKAGPRDGELWVQRLKEEYQALIQYVQKNKESDSDWFFLESNKEGTRW FGKCWYIHELLKYEFDVEFDIPVLYPTTAPEIAIPELDGKTAKMYRGGKICMTDHFKPLW ARNIPKFGIGHAMALGLGPWLAVEIPDLVSKGVIHHK-XXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSAMNPEYDYLFKLLLIGDSGV GKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYR GAHGIIIVYDVTDQESFSNVKQWLQEIDRYASENVNKLLVGNKSDLTTKKVVDFTTAKEY ADHLHIPFLETSAKSATNVEQAFVTMAAEIKNRMGPINPTPSVKINASTPVKQNSGGCC- ------------------------------------------------------------ -------------DPRIRRRKKGRTLYLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEQL KPGDLVGVNKDSYLILETLPAEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELIEAVVLP MTHKERFTSLGIQPPKGVLLYGPPGTGKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGA KLVRDAFSLAKEKAPAIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNHD IKVIAATNRVDILD---------------------------------------------- ------------------------------------------------------XXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXQKTHHLAVTRNYLSQPRLTYKTVSGVNGPLVILDGVKFPKFAE IVKLTLHDGSTRSGQVLEVSGSKAVVQVFEGTSGIDAKHTTCEFTGDILRIPVSEDMLGR VFNGSGKPVDKGPTVLAEDYLDIQGQPINPWSRIYPEEMIQTGISAIDGMNSIARGQKIP IFSANGLPHNEIAAQICRQGGLVKL----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------LMKSAIGDKMTRDDHADVSNQLYACYAIG KDVQAMKAVVGEEALTADDLLYLEFLLKFEKNFIAQSPYENRTIFETLDIGWQLLRIFPK EMLKRIPQDTLAKYYPREAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXKPAFKVADITLADWGRKAIEIAENEMPGLMMMRTSYGPQKPL KGARITGCLHMTVQTAVLIETLLELGAEVQWSSCNIFSTQDHAAAAMAKRGVAVYAWKGE TDEEYVWCIEQTLVFPNGEPLNMILDDGGDLTNLVHTKYPQFLAGIKGVSEETTTGVHNL YKMLAKGELKMPAINVNDSVTKXKFDNLYGCRESLV------TDVMLAGKVRGVARYGDV GKGCAHALRAFGSRGIITEIDPINALQAAMEGYQVTTMEEAVKEARIFVTTTGCKDILRG EHIEKMLEDSIVCNIGHFDCEINVKWLNDNCLSKENVKPQVDRYTLKNGRHIILLAEGRL VNLGCAMGHPSFVMSNSFTNQ--------------------------------------- ----------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXMSTSNVENVSPQILRQVTKELMDLQKDPPEGIKVTINEDDITDIQAAVDGPEE TPYAGGYFRVKLVLSKNFPSEPPKGFFLTKIFHPNIANNGEICVNTLKKDWKPDYGIKHI LLTIKCLLIVPNPESALNAEAGKMLLEQYDDYFTRAKMFTEIHAK-MSRSISDLVRSNPF ASPFGLKVNETRTVAALTETYSCEYGSTKFYAXCGLGGILSCGITHTAVVPLDLVKCRIQ VDPAKYGNLIKGFKVSVAESGMKELGKGWAPTAFGYSAQGLCKFGLYEVFKHVYGDLIGE ENSYLWRTSLYLAASASAEFFADIALCPMEAVKVRIQTQPGFARTLREGAPKIFRDEGIW GFYKGIVPLWGRQIPYTMMKFACFERTVEALYKHVVPKPRSECSKGEQLIVTFVAGYIAG VFCAIVSHPADTIVSKLNQAKGSSFITIGKNLGFWGMWKGLTPRIIMIGTLTALXWFIYD SVKVYFRMPRPPSPEM---------HWVNERYAAVALLPLIPTALAFILDTLLSAMVLHT HWRLSGVAQDYIHLTITAFGSICYFNYTDIGFANAARLLYTQLXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----ARGIEKHWRLIGWGQIRRGTPVPPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--- ------------------------------------------------------------ ------------------------------------------------------------ --------RKTFNIKNDFTPAEEEQVRKENEWCEEKNKRLSKGGKKGGKKKVVDPFSKKD WYDVKAPSMFNNRNIGKTIVTRTIGTKIASDGLKGRVFEVALADLQNDEIAFRKFKLMSE EVQGRNVLTNFHGMDMTTDKLKSMVKKFQTLIEAHVDVKTTDGYLLRLFAIGFTARRQNQ DKKTSYAQSTQVRAIRKKMVDIMTREVSSSDLKDVVNKLIPDSIGKDIEKVSQGIYPLHD VYIRKVKVLKKPKFDLGKLLELHGEGGTTTVGEGGEKIERADNYEPPVLESV-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------TANN VEIIVPVPMDADSPKFKTTNGSCKYSPEQNAVIWTIKSFPGGKDFMMRAHFGLPSVKSED AEGKPPIHVHFEIPYFTVSGVQVRYLKIIEKSGYQALPWVRYITQNGDYQLRTQ------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------VEDFCNXIHRSIMKEFKYAIVWGSSVKHQPQKVGKDHQLNDEDVIQIVKKX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XX---------------------------------------------------------- ------------------------------------------------------------ ------------------------------QLELIFTPKSGKETRMEVFTFKDKGGVGLA MYNTDVSITGFAHSCFQFSLKKKWPLYMSTKNTILKKYDGRFKDIFQEVYEAKYRKDYEA AGIWYEHRLIDDMVAQALKSNGGFVWACKNYDGDVQSDVVAQGYGSLGLMTSVLMCPDGK TLEAEAAHGTVTRHYREYQKGKPTSTNPVASIFAWTRGLEHRGTLDNNPDLIRWCHGIEK ACVDTIDGGKMTKDLAGCIYGLKNVKESQYLNTQDFLDAVKEQFDXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFGDLKAASGLKALNDYLQDK SYIEGYQPSQADTATFGKLAGPGKDYINVLRWYNHINSYGAEKASFPGQKSSEEVNGSAP AKEAEDDDDFDPFKSEAERIKQERLAAYEAKKSVAIIAKSNIVLDVKPWDDETDMAELEK AVRTVEADGLLWGASKLVPLAYGIKKLQITCVVEDDKVGTDF------------------ -----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------QKLRECETLLLNDFFIVGLYADFMENARLFIF ETFCRIHQCISISMLAEKLNMSP-EAEKWIVNLIRNARLDAKIDSKLGRVVMGTQGISPY QQVIEKTKNLAFRSQMLVMNLEKKLSTKD-----------DGVTFPNSGQTVVIHYTGVL TNGKKFDSSNDLGKPFKFRIGQGQVIKGWDE-VTKMIVGETANLTCTPDYAYRASGAGGV IPPNATLIFEVELLGLEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXVACLAAIALAEPSTYFREEFWESRWVESTSKGAEQ GKFTWTAGKFYNDAEKDKGLQTTQDARFYGISAKFDKPFTNEGKPLIIQFTVKHEQEIDC GGGYIKLFSSDLDQKNMHGDSPYYIMFGPDICGYSTKKVHVIFNYKGKNLLTKKEIRCKD DVLSHLYTLIVRPRHTYEVKI--------------------------------------- ------------------------------------------------------------ ---------------ADEHLYKYSDIGAIGFDLWQVKSGTIFDNMLITDDEKFAEEVGEE TWGKTKDGEKKMKDTFDEEERKKREEEEKKRKDEEKKDEEEDEEXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------- ------------------------------------------------------------ ---------QKIVDTMKVVEKIRAKRNAAFIRERLRVPKALKMAVQLKELEKNYNLIQLP AAL-AAHRIVMVRHGESAWNAENRFCGWFDADLAESGIKEAKLAGQRLKEKGFSFDVAFT SVLKRAIKTLFLIQDGLDLHWIPVYRHWRLNERMYGALQGLNKSETAAKHGEEQVKIWRR SYDTPPPPVGIDSEYWPGKDPKYKYVDINLIPKTECLKDTVARALPYWFDVIVPEIKKGQ NVLI-AHGNSIRAMCKHLDNISDADIMNLNIPTGVPLIYELDKQMKPLKHHYLATDEEVK QALAKVAAQGKAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXMGIDIRHNKDRKVHRKEPKSQNVYLRLLVKLYRFLGRRTNS KFNKVVLKRLFMSKTNRPPLSLSRLARHMKKTGREGKIAVVVGTVTDDPRIFEIPKLNVC ALHVTDRARARILKSGGQIITFDQLALKSPKGQKSVLLQGPRKARKAYRHFGAAPGVPHS HTKPYVQSKGRKFERARGRRKSRGYKNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------------- -------------------YCCRRMILSHVDLIEKLINYAPLEKXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMRATGQLKEYRVLGRMMPTSKVRV QPIYQMRIFAPDRLQAKSRFWYFASMLRKVKKTQGEILCCSQVNEKKPTAIKNFGIWLRY DSRSGSHNMYREYRDLTTSGAVTQCYRDMGARHRARASSIQIMKVQVIAASKVKSKNLKQ FLDSKIQFPLPHRVNRQLHHPRFTTARPHTTFSAHEEMKRFWDKNLKRPNSPWWVYRPHL PMLTSLCHRMTGIAMGVAFYTFSISVFLAPGDFPCYVDYIKNLGISPVLMFPAKTIVAFP LVYHYINGIRHLTWDAGHGYELKTQYKTGITVLASIAYWAGSADLSAYRDQHYKGSRGEQ EKQLLTSTTLYIGNLSFFTTEEQIHELFSRAGEVKRIVMGLDKFRKTPCGFCFVEFYTRE DAENAMRYINGTRLDDRIVRTDWDAGFIEGRQYGRGKTGGQVRDEYRQDYDTG------- -----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMIIFKDVFTGDELFSDSFPETVYKVKGKDDKAIGGNASQGVDIVMNSKKDYMTHIKS YMKSVKDYQLFCGLALMKWETPYMFFFKHGLDEEKVMAVQYKDGVVLGADSRTTTGAYVA NRVTDKLTRVTDKIYCCRSGSAADTQAIADIVAYHLSVHQMEIGEEPLVKTAAKIFQDLC YNYRDQMSAGIICAGWDRKEGAQVYCIPLGGMCIRQPFTIGGSGSTYIYGYVDATYKPEM TVDQCLEFTKNAVTLAIQRDGSSGGIIRLATITEKGIERQTVLHNDLPKVXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------K-GGDMSKNVPSQMAKLNQQMVKMMDPRVLQSMGGVAGLQN MMKKFQQGA--------------------------------------------------- ----------TVSERLKFRVSLYELRENRRIKPKTLLSVVSNLLYERRFGPYFVEPVIAG LDSVTNEPFVASLDLIGCPMVTGDFVVSGTCNEQMYGMCESLWVPDMNPDQLFETISQAL LNAVDRDAVSGWGGIVHIIEPKRVTTRTLKARMDXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMVK EDRTAWKSNYFVKMTELMDNFPRCFIVGADNVGSHQMQKIRITLRVLMGKNTMMRKAIRG HMENNPALEKLLPFIKGNVGLVFTKGELSEVRKIIQENKVAAPAKAGVIAPLDVTLPAQN TSLGPEKTSFFQALAIQTKISKGTIEILNDVKLIKVGEKVGASEATLLNMLNISPFTYGL QIQMVYDSGTVFDLSILDITDDDIRARFLEGVSNITSLSLAIGYPTLVSVPHSIVNGFKN LLAVAAATDIEFKEAQTLKE---KGKLIAVIGDEDTCTGFLLGGIGELDKHRKPNYLLVD KSTSIADIEDAFKSFTARDDIAIILINQNIAEMIRLLIDRYTKALPAILEIPSKDHPYDA NKDSILRRARRMCAAEDFR---------LSANFTQDEIRRLGVRFAKLDRDGSGSISIEE FMTLPEIRKNPIAHRVISVFDVDGNGEVDFKEFIRGMSLISCKGDNVKKLRFAFAMYDMD KDGLISNGELFSTLKEMVGDNLENIQLQQIVDKTIMYGDQDGDGKISFEEFVMVVGEKD- --------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXLYEEVKLYRTAREREKYDNLADLYALINTLQCLEK AYIKDSVTPKEYTAACSKLLVQIKAAFKQAQDEEYRSIEEFAKKSKLNCAAALDRIKEDR PITIKDDKGNTSRCIADIVSLFITIMDKLKLEIKAMDEIHPDMRELMDTMNRLSLLPADF EGKVKVNEWLQTLAGMQASDELTETQVRQLVYDLES-----------XXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPRFIEKQVDGEKNGKTR RVPVKRASKYYPTQEKSWRLRTPFSQHKRHLRESITPGTVLILLAGKHKGKRVVFLKQLA TGLLLVTGPYHLNGCPLRRINAIYAIATKTKLDVSSVKLPERVNDAYFKRKEIKRPKHTE GEIFTTKKEEYTPSAERKEDQDVVDKQLLDVIRQHPEKKYLFGYLGAMFSLKNGDRPHKM IFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXTLERTISLYPLTNYTFGTKDAQYEKDQSVIARFD RMKEEFKKSGMRRSAEGVLIVHEHGLPHVLLLQLGTSFFKLPGGELKPGEDQVEGLKRLL TEMLGRQDHPPVDWVIEDTIANWWRPNFEAPQYPYIPAHITKPKEHKRLYLVQLPEKALF AVPRNYKLVAAPLFELYDNAAGYGPIISCLP-----------XXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------------------- --------------------------SFMENYFTSQRDNIFRNVEVLIYVFDVESRELEK DLNYYQSCLEAILQHSRNAKVFCLIHKMDLIQGDHQDRIFAEREANLHLLSRPIATSIWD ETLYKAWSAIVYQLIPNIQQVESSL----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------TPEDAKVMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMAS PEDKAYEIMRELDVSYVLVIFGGLTGYSSDDINKFLWMVRIGGSTDRGEHIKENDYYTPQ GEFRVDKDGSPTLLNCLMYKMCYYRFGLVYTESGKPTGYDRVRNVEIGNKDFELDVLEEA YTTEHWLVRIYKVKDLTNRGNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQEAFCLFDNKGDGKI FGHQLGEVLRAMNQNPTEAEVKKCQDPDRRISFDQVLPILYTVIKNRVEPAVDEFIEGFR VFDKEQNGTISSAELRHMLTNLGEKLSDEEVNELLVGHEDPQGNVNYEEFVKAVING--- ---------------------------------ETLEDLKLHLQSTDYGNFLANEASSLS VQVIDDKLREKMVIEFQHLRNQCLKPLSTFLDYITYGYMIDNIILLVTGTIHQRAISELI PKCHPLGSFEEMETLNIATNPAELYNAVLVDTPLANYFIDCISEQDLDEMNIEILRNTLY KAYL-------------------------------------------------------- ------------------------------------------------------------ ---------------------NIIWIAECVAQRHRAKIDSYIPIF--------------- ------------------------------------------------------------ --------------------------------HEGRVGSLSWNAHILSSGSRSGYIHHHD VRIADHLI-GSVAAHTQEVCGLRWSPDSKYLASGGNDNLLNIWSSDLGASLYSFNQHQAA VKALAWCPRQSSLLASGGGTADRCIRFWNVNTGTCIKSVDTNSQVCALLWSKDYKELISS HGFALNQLTVWTYPTMTKVAELTGHTSRVLHMAMSPDGSTVVSAAADETLRIWKCF---- ------------------------------------------------------------ -------------------------------------AVAIYGIIMAIVISNAQNRHAGF SMFGAGLTVGFSNLFCGVCVGIVGSGAALADAQNSSLFVKILIVEIFGSAIGLFGVIISI LQVTHARMGDK----RRLTKELQDAVDEANILQWMGLIVPESAPYNKGAFRIKIDFPAEY PFKPPKITFQTMIYHPNIDEKGQVCLPIISPENWKPATRTDQVIQALVALVTDPEPEHPL RADLAEEYTKDRKKFMKNAEEHTKKYGEKRPSDGASATFPQQCSALRKNGFVVIKARPCK IVEMTTSKTGKHGHAKVHLIGIDIFTGKKCEDICPSTHNMQVPNVTRKEWELIDLSEGYF SLMNDEGEMRQDLKITATVWKAMDEEVVKDLKTAKXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXKVEVKK-VNPLFEKKSKNFGIGQDIQPKRDLSRFVRWPKN VRLQRQKAILYKRLKVPPSINQFTQALDRQTATQLFRLMEKYRPETYQEKMRRLKSRAEE RVKGKEDVPTKRPPVIRSGINTITSLIEQKKAQLVAIANDVEPIEIVLFLPALCRKMGVP YCIVLGRVVHRKTVTSLAFTQVNPEDKTALTKLVEAVKTNFNERGEEIRKHWGGGVMGQK SQARIAKLEKAKAKELAQKMRYVAAYLLAVLGGNEHPGEADVKKILSSVGIDADNDCVKK VVGELKGKNLEELIAAGRQKMASMPSASGAAPKEAKKEEEEDEDMGFGLFDMPITKIHAR QIFDSRGNPTVEVDLTTDFGFFRSAVPSGASTGIYEALELRDKDPHQYHGKSVLKAVGNI NSIIAPALVLDLTDQAAVDKIMLDLDGTENKSKLGANAILGVSLAVCQAGAKKKGVPLYR HIADLAGNKDLILPVPAFNVINGGSHAGNKLAMQEFMLLPTGASSFTEAMRWGSEIYHHL KSVIKAKYGQDACNVGDEGGFAPNIQNNEEGLELLKVAIEKAGYTGKIEIGMDVAASEFC KKYDLDFKNPKSDPATWLTSDQLFDVYKGFIEKYPVVSIEDGFDQDDWEAWTKMNAIQLV GDDLTVTNPKRVKTAIEKKACNCLLLKVN------------------------------- -------------------------------------------------------GGPPS AGAYRRRDSDPTNFRKFYERGDFPILVEHSTMGNKIAWKAEIEKLDYHHYLPLFFDGLCE LDFPYEFFARQGIHDLLEHGGTKVLPVIPQLIIPIKNALSTRNYQIMCITMKVLQHLVVS GDMIGEALVPYYRQILPIFNVFRCKNVNIGDGIEYSQRKRENIGDLISE----------- -----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXYHS QFTSPAQVIGNMALLPLRTQFKGPAQDIIDEALLYFKANVFFRNYEIKSEADRTLIYLTL YITECLKKLQKAKSKNEGLKEMQSLAISKFSIPGEAQFPLNAMYSKPANRQEEDTMRNFI QQLRQEIGVRLCEKVFDPDTDKPSKWWMCFVKRKFMDKSLSGPGQXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX----------DGGVQGKVTFTQERNVTIKGRITGLSPGKHGYH VHTSGDLTDGCTSMGVHFNPHNRNHGGPKSRVRHVGDLGNLIANSIDTSDYVISLNGPNY IVERGLVIHHDPDDLGLGHFPDSNTTGHSGERVACGVI----MVNFPIDEIREIMDKKKN IRNMSVIAHVDHGKSTLTDSLVSKAGIIAGAKAGEMRFTDTRKDEQERCITIKSTAISLY YSLPEKDLICSFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQA IAERIKPVLFMNKMDLALLTLQLAPEELYQTFQRTVENVNVIIATYGEDGGPMGEVMVDP AKGTVGFGSGLHGWAFTLKQFSEMYSEKFKIEAHKLMKRLWGDQFYSYVRGFTQYILDPI YKVFEFCMPKADAIALSEKLGVKLTVEEKENQEKQLMKVIMRKWLPAGDALLQMITIHLP SPVTAQKYRMELLYEGPHDDEVALAIKACDPKGPLMMYISKMVPTSDKGRFFAFGRVFSG VVMTGMKARIMGPNFIPIKSIQRTILMMGRYTEPIEDVPCGNVCGLVGVDQFLIKTGTIT TFENAHNLRVMKFSVSPVVRVAVECKNPADLPKLVEGLKRLAKSDPLVQCSIEESGEHII AGAGELHLEICLKDLEEDHACIPIKVSEPVVSYRETVSEESDRVCLSKSPNKHNRLYMKS RPMPDGLAEDIDKGDVTPRQEVKERARYLAEKYDYDVTEARKIWCFGPETNGPNVVIDCT KGVQYLNEIKDSVIAGFQWASKEGALCEENMRGVRFDIHDVTLHADAIHRGGGQIIPTAR RCFYASVLTAAPRMMEPVYLVEIQSPEAAVGGIYGVLNRRRGHVIEENRIIGTPMFVVKA YLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILVVTDTRKRKGLKEGIPPLDNFFDKLX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- ---------------------------RSLLWYHDAAIRCVEFCPDVNVIITGSWDCSVK LWDPRGPNQAGSFSQPDKVYTMSLCGDKLIVGTAGRRVLVWDLRNTGYVQQRRESSLKYQ TRCIRSFPNKQGYVLSSIEGRVAVEYLDPAPEVQKKKYAFKCHRIKEDGVEKIYPVNAIA FHSSHSTFATGGSDGFVNIWDGFNKKRLCQFHRYPTSISALSFSHNGSLLAIASSYMFED GPPEDAVF------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXMDDEAETYKLWRIRKTIMQV---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------HPDEAVAYGAAV QAGVLGGEEDTGDIVLLDVNPLTMGIETVGGVMTKLIGRNTVIPTKKSQIFSTAADNQPT VSIQVYEGERPMTKDNHLLGKFDLTGIPPAPRGVPQIEVTFEIDVNGILRVSAEDKGTGN KNNIVINNDQNRLSPEDIDRMINDAEKFAEDDQKVKERVEARNELEGYAYSLKNQIGDKE KLGGKLSSEEKETIETALDEHIKWLEKNHDADVE----HKKQLEEVVQPIISKLYQGAPP TDGSEERDELXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXPKIGINGFGRIGRLVLRNALEKLEVVAINDPFIDPEYMVYMFRYDSTHGQ FKGTVTLIVNGKPIHVYMERDPKSIPWGKVGADYVIESTGIFTTIDKANVHLEAGAKKVI ITAPSADAPMFVMGVNEESYDASMNIISNASCTTNCLAPLAKVIHENFTIIEGLMTTVHA YTATQKTVDGPSSKDWRGGRTAAQNIIPSSHGAAKA----------------------HV SVVDLTVRLEKGASYDEIKKVVKGPLKGILFYTEDEVVSTDFNTSSYSSVFDAKAGIALN DHFVKLVAWYDNEYGYSNRVVDLIKYAHKRD----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------HFEEAMKFARRSVTHNDIRKYEMFAQTL QTSRGIGSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXVIWSLINGSFCSHKIMTKKRHLCKNEYNLTGICNRKSCPLANSKYATVREENGVCYL YVKTIERAAFPRKLWEKIKLSQNYEKALEQIETELLHWSDFYIHKCKQRFTVITQYLTRT RRLMLKRQKKLVPLKRKVERRESRREMKALVAARLDVAIENELLNRLKQGAYGDIYNFP- ---------------------------------------------AATPRMKKFSIYRWN PEKPGDKPHMQTFEIDLEDCGPMVLDALIKIKDEVDPTLTFRRSCREGICGSCSMTINGG NTLACLCKIDENTSKTTSIYPLPHMYVIKDLVPDMNNFYAQYKYIEPYLKKKNFTEEDNG KTSFLQSPADRAKLDYMVDCILCACCSTSCPSYWWNGDKYLGPAVIMXAYRWIMDSRDDF KKERLAQLRDEWSLYRCHTIMNCTKTCPKGLNPGAAIGELKKVMLGYESKGIPRQXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------- ------------------------------------------------------------ --------------------VIPLYVPQCNDCKFCRNPKTNLCQKIRVTQGQGLMPDGTS RFTCKGKQVLHFMGCSTFSEYTVVAAISVCKVDVAAPLEKVCLLGCGISTGYGAALNSAK VEPGSICAVWGLGAVGLAAIMGCQKAGAARIIGIDVNPAKFEIAKQFGATECLNPXDFDK PIQQVLIDSTDGGPDFTFECIGN------------------------------------- -----------------------------------------------------------X XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------KDTSVGTLSHRVTNQLMGLKGLFQQLQEIHSYLDKVSTGQLPINHQI IYHLQDIFNLLPDVNLQSFVKAVYVKTNDQMLVVYLAALIRSIIALHNLINNKVQNRDAE KNEGKEKE------RFWQLVGKRERKIIIIGLDNAGKTTILYKMLLDEVVSTTPTIGSNI ERVVYKNMTFLLWDLGGQEALRRTWRNYYDGTDCIILVVDSTDHERLEIVGKTLEQMLES EALDGTALLVYANKQDMKNALKPAQILKILGLAEIKDRAWQIQGSCALTGEG-------- ------HVIPIRRVPLTDQSQLPANYSATPGGTLFSTTPGGTRIIYDREFLMQCRNSPHA KSPPANLPNIPGVTHPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXX--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------H SITAIASYTGYNQEDSVILNESAVDRGFFRSAFYRSYKDSELKKGLDQEENFEKPDRSCV QGMKNASYDKLDEDGIITPGIRVSGDDVLIGKTIVLPETEDELEGHQKRFTKRDNSVFMR KSETGIVDQVMLTINQEGYKFCKIRVRTVKIPQIGDKFASRHGQKGTCGIRYRQEDMPFT AEGITPDIIINPHAIPSRMTVGHLIECLQGKVSAIRGEIGDATPFNDAVNVKKISDML-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------LVKDLPGGFSFENCRRNAVLEQGF KMPKAVKTGTTIVGVVFKDGVVLGADTRATEDTIVADKNCSKIHFITKKIYCCGAGTAAD TEMTTNLIASQLELHRLNTGRQPRVCTANRMLKQMLFRYQGHISAALVLGGVDSTGPHLY TVHPHGSTDALPYVTMGSGSLAAMAVFESRYKVDMERGEATELVKDAIKAGIFNDLGSGS NVDVCVITKEAEHIRPFEVAXQKGERQGKYQYPKGTT---------------XXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXETADEFDARYEKFLNRPDIDGWELRKAMNDL QGHDLVPEPKLVIAAMKACRRVNDYALAVRYLEAVKDKCGPKVKEIWPFMVKEIGPTLKE LGILTPEEMGYDKPELACKDVLDM------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AFMSKTGHSVHMRGLPYSATENDIQQFFMPINLENVVIG FGEGRPSGEADVEFANHSDAVQAMRMNNALMERRYIELFYKDKDKPTQIRYSNITAAKAV SDAIRTSLGPRGMDKMIQAGAGDVTITNDGATILKQMQVLHPAAKMLVELSKAQDVEAGD GTTTVVVIAGSLLDAAHKLLLKGIHPTTISESFQRAAAKACSILEGISVPVQLSDRESLL KSATTSLNSKVVSQYSNILSPICVDAVLKVIDPAKDTNVDLHDIKI-------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------KTITVLVRGSNKLVLEEAERS IHDALCVIRCLVKKRALIAGGGAPEIELSLQLMEYCQTLTGMEQYCFRAFAEALDIIPFT LAENAGLNPISTVTELRNRHAQGEQTAGINVRKGAITNILEENVVQPLLVSMSAIHLAAE TVRSILKIDDIVNCI--------------------------------------------- -----DRSKVQVSIALKFYKDLQEHGADQLIKREYGSFLTSPESGYNVSILFDDKLPANR DEMIKKAGLLKRNCFASVFEKYFEFQQKQKRAVIHYRDDETMYVEAKKDRVTVIFSTVFK DDDDVVIGKVFMQEFKEGRRQFQQAPQVLFSHKEPPMELQNTDAKVGDNIGYITFVLFPR HAAKDNTINLIHTLRDYLHYHIKCSKAYIHSRMRAKTSDFLKVLNRATPEPKTVEKK--X XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGKMDNAQKQQLMEQVKA QIAVANFQELLQKMSDKCFKKCVSKPGTSLDNSEQKCVAMCMDRYMDAVSLVSRTYAQRV TKEKSRLMNRLFGRAKPTQPAPNLTDCIASVDGRGESIDKKIARLDQELAKYKDQMKKMR DGPSKNMVKQKAMRVLKQKKMYEQQRDNLMQQSFNMEQTNYGIQSLKDTKTCVDAMKVSV KEFKKEYKKVNIDQIEDLQDTLEDLTEQCSEIQEVMGRSYGMPEIDDDELDAELEALGDE IALDDDTSYLDEASKAPNAPTGVPGADSVTNKDGVAVDEFWLPKIAA-MTPLNPATPASP QLQNIVCTVNLGCKLDLKKIALHARNAEYNPKRFAAVIMRIRDPRTTALIFSSGKMVCTG AKSE-------------------------------------------------------- -------------------------------------------------------XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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ISSPTGSKDLQMVNISLRVLSRPDSAQLPAIYRQLGVDYDERVLPSICNEVLKSVVAKFN ASQLITQRQQVSLLVRKELIDRARDFNIILDDVAIT------------------------ ------------------------------------------------------------ -----------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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EKDEISKKWEESHLAKKIAAKEKRKTLTDFERFKLMKAKQARNRLIKIEFGKLRNALKXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEAKPSWAEQVELGDEDVLPPSSEEFNENT NIRKITEYKFNEDGKKVKIIKTYKVETCKVSKSVARRKGLKKFGAAYGDPPGPNPANTVE EIMMQYVHAKELPEDDPLSRLKVSCRLCKGDHWTTKCPYKDSIAPLQELDQRTGKYVPPS LREGGNRKGESMSMDESATIRVTNLSEDTRENDLQDLFRPFGTIARIFLAKDKATGQSKG FAFINFHNREDAARAIAGVSGFGYDHLILNVEWAKPSXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------ERKKQP KASAMKSAQAINAAQRQGLEIETSKKFAAGQNKQHAAAKNTAKLDRETEELHHETVGFDV GRLIQQGRQAKEWTQKDLATHISEKPQVVNEYESGKAIPNQNVLSKLERALGVKLRGKDK GQAIQPKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXMDVFLMVRRKKTTMFIDAKESTTVLE--------------- ------------------------------------------------------------ ------VYRYHAVVLRARFDQYKDEDMVKAKQLLGDGEEELFLNRHPQPFKFPNSPGGVA YGRTPHFPDSGLDMWHPLERAQYPEYFAKREQRKMEYIERWEKKYGKAEXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------------- ------------------------------------------------------------ ------------TRLPQIYTNLGSDYDERGLPSIGNEVLKAVGAQYDARELITQREIVSQ QVNDELTTRAAHFGLILDDISLTHLTFGREFTEAVEMKQVAQQDAERARYLGEREEQLKL AAIIRAEGDAVAADLLATAFANAGEGLVELRKIEASEDVAYQMS---------------- ---MKTINLTQTVKIPDGVLVTVKSRKVTVKGPRGTLRRDFRHMAIDIKMVKGNQLVVEK WFGIRKELAAVKTVCSHVQNMIRGVTEGFRYRMRSVYAHFPINVAISESNTVVDIRNFLG EKFNRQVRMLQGVTCIASKDMKDEFVLEGNDIELVSRSAALIQQSTTVKNKDIRKFLDGI YVAKE------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------IVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLIFILAD VPLPLGTITILCIDLGTDLVPAISLAYEQAESDIMKRMPRDPKRDKLVNNRLIGMAYGQI GMIQASGGFFTYLVIMTENGFWPDRLLGIRKEWDSKAVNDLPDSYGQEWTYGQRKVLEYT CHTAFFVAIVIVQWTDLIICKTRRNSVIHQGMINHHLTFGLFFETSLAALLCYCPGLDKG LRMYPLKWTWWLVPLPFS------------------------------------------ -------------------------------------------VYKQVCAACHSMNYMFY RNLVGVIMTEDEAKAEAEEVMVTDGPDDTGAMFERTGKLSDRFPKPYANDEAAKASNNGA LPPDLTFITGARHGGEDYIFALLTGYQDPPAGIEIREGMHYNPYFPGGAISMARSLYNET IEYDDGTPPTASQLAKDVVTFLRWTAEPEHDDRKRMGIKAAMIGLVAVAFYYKRHKWSAL KSRKIA------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------IAHYDSTAEEILEQCDGRLDMVVCGVGTGGTITGISRKIKEKCPTCKVIG VDPFGSILAEPDNQSFYEVEGLGFDFIPTVLDRSVVDRWYKCSDKPTFQMAKRLIREEGL LCGGSSGAVMYCAIQAAKDFDLKEGQRMVVLLPDSIRNYMTKFVSEDWLRARSLXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-- ------------------------------------------------------------ ---------------------------DGCDEVVLETEITNRAALHLYENLGFVRDKRLF RYYLNGVDALRLKLWLKGIESLMFHLTPNQRKCLKEEIHKDVLVTGEYTLSDVPGQTANL KVTDSKGHVLYNKDDATKGKFAFTTEEYDMFEICFESHIPAGGHGGEREVFIKMKRGVEA KNYADIAKAEKLKPMEVELKKLEDLSESIVNDFAYMRAREEEMRDTNESTHSRVLYFSIF SM-------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPFVA PKQEKCDKCDKSVYAAERLEAGGRVYHKLCFKCSVCKMAVSLNNYAQADGVLYCKTDYQK TVLAKNSQV--------------------------------------------------- ------------------------------------------------------------ ------------GVDVGHTTKDNMFTLNEVECLGACVNAPMLQVNDDYYEDLTVEDVNEI IDDLRAGKKPKPGPRSGQGKRFASEPACGLTSLTTPPYGPGFKVRSDL------------ GTYGTVFKAKNRETQEIVALKRVRLDDDDEGVPSSALREICLLKELNHKNIVSL------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------XXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXMPRFVPYLTKEQQDELRSIAQAIVAPGKGILAADEST GTIGKRFQSIGVENVEENRRIYRQLLFTALPNYISGVILYHETLYQKGDDGKTFAQLLRS QGIIPGIKVDTGVVPLAGTDGEGTTQGLDGLAERCAQYKKDGADFAKWRCVLKISSHTPS YLSVLENANVLARYAMICQQAGIVPIVEPEVLPDGDHDLETAKKVTEEVLAFVYKALADH HIFLEGTLLKPNMVTAGQSSAKKYTPQEVALATVTVLRRRVPAAVPGITFLSGGQSEEEA TIHLNAINQKPWALSFSYGRALQASVLQAWKGKPENVKAAQDELLKRA------------ ------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------LLQKCAATALSSKLVAHEKDFFAHMVVDAVMLLDELLP LDMIGMKKVQGGALEDSQLINGVAFKKTFSYAGFEMQQKRYENPKLSLLNIELELKAEKD NAEIRVDSVEEYQLVVDAEWSILYDKLEKIYKSGAKVVLSKLPIGDVATQYFADRDMFCA GRVPEEDLKRTMQACGGAIQSTVTNMNLGTCE---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------KGNNAIPNGHFHKDWQ THVKTWFNQPARKERRRVARRKKALAIAPRPAAGSLRPQVRCQTFKYNTRLREGRGFSLD ELKAAGINKKEARTIGISVDVRRRNKSVESLQLNVQRLKEYRSKLILFPKKLSKPNKGDA TEEEMKLATQLKGKLLPRTAWVKPEKARAITDEERKVKVFDRLRQARAHKRLAGKRAKKA KEAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--KRQFFVGGNWKMN GTMSSVDGIIAFLNEKNKKTEVVVAPPFVYLGYAREKLIAVAAQNCFKVDKGAFTGEISP AMIKDNGATWVILGHSERRNVFGETNQLIGEKLAHALAEGLNVIPCVGEKLEEREAQKTD EVIYKQMDFKDWARVVIAYEPVWAIGTGKTATPEEAQQVHKFLREWIS------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------ERLTTPLLEWIESKRPWLEDRSVMKSRPLTQQ NLEEFRNYRSQQKPMRLEEKAKLETTFNTLQTRLRLSNRPAYMPINGKLVSDITIAWKKL EKAEKGFEEWMLSELQRLERLEHLVQKFKVKCSVHENWSAGKEENLRQNDFAKLSLNEIK AIMKKHEAFESDLTAHEDRVEQLSAIAQELISLG-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------NLRFHIEEEGKVTAENGEKLKAEPE DVDKFRASLSKLGDIYVNDAFGTAHRPHSSMVGCNLPIKASGLLLKKELSYFAKVMEKPE KPYLAILGGAKVADKIQLIENLLDKVTDMIIGGGMAFTFLKVNNNMEIGKSLFDEEGSKI VGKLMEKAKAKKVNITLPVDFVTGDKFDAKATVGAATVKEGIKGEWMGLDIGPQSIKLFT DAIMKAKTIVWNGPPGVFEMDNFAKGTKGVMDAVVNATKKGAITI--------------- --------------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXFVPLFDRVLVQRFAAETKTKGGVLIPEKAQGKVLDAKVVAVGPGTR SSKGDLIPLNVVVGDRVILPEYGGTKVVLDDQEYFLFRNQDILGKLQXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXX------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------EYQKKTKALILRAAVVRNHIQVHSPPRDGNQCTEMTLVPGNAASXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------------------- ---------------------------------SLDWSTQFPELLLSSYSGNKDSPNEPE GVALVWNVKFKKTTPEFIFHCQSPVTSACFANFHPNLIVGGTYSGQIVLWDNRSHKHTPV QRTPLSALAHTHPVYCIDVVGSQNAHNLVSLSTDGKICFWSLDMLSQPQDSLELQYKQNR VASWCCSFV--------------------------------------------------- ------------------------------------------------------------ ---------------NSGLNKCRWHQAGHTIAAGDDSGKIHIYEVGEPLAVPRSDDWSKF SHTLQELKLEQVEQEEEN------------------------------------------ ---------------------------------------HFYRNATFYCKIVDKHLSLLA AKHLETRFVKMDAERSKFLVDRLRIKVMPTVCLVKDGKTVDYIVGFDDLGGKEDFPTEMM EWRIAQANVINYSGDLLTPPVAGASKKTIRGKVEDDXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- ------------------------------------------------------------ ---YEREVWDMHGVFFXNHPDLRRILTDYGFEGHPFRKDFPLVGYVEVRYDDEVKRVVAE PVELIQEWRKFDYTTPWENFPAFRAS---------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------KNEFRMAFGANVEIKTSKEL KIQGCIGSCISVGASPSVSESELGIGGTCQWKMCGVYPNSTYAFYFEVVNQHNAPIPQGG RGYIQFVTQYQHSSGQRRMRISTVARNWVDASVNIQHIAACFDQEAAAVLMARMAIFRAE TDDGPDVLRWLDRMLIRLCQKFGEFNKDDPSSFRFSEQFTLYPQFMFHLRRSQFLQVFNN SPDETSYYRHMLFVEDLTQSLIMIQPILYAYSFNGPPEPVLLDTSSIQPDRILLMDTFFQ ILICHGETIAQWRKLKYQEQPEYENFKQLLQAPVDDAQEILQTRFPMPRYIDTEAGGSQA RFLLSKVNPSQTHNNMYSEGGGHVLTDDVSLQVFMEHLKKLAVTS--XXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDRLNIFPSRMALTLMKARLK GAQKGHSLLRKKSDALTMKFRGILRKIIDTKTLMGDVMKEAAFTMAEAKFAMGDFNNLVL QNTDKAQLKVKTKKDNVAGVTLPVFEAFHDGSDAYEYTGLARGGQQIDRIKKNFAKAVDM LVDLASLQSSFVILDEVIKVTNRRVNAIEHVIIPKIERTLDYITTELDEREREEFYRMKK IQRKKAEMR--------------PLRVLVTGAAGQIAYSLLYSVAKGDVFGPNQPISLVL LDIEAMLGVMTGVVMELMDCALPLVKEIVPTADIVAAF---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------XXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXX--------------------------------------------LKIARD KSLGKDYLLCDYNRDGDSYRSPWTNVYDPPLADGALPSEKLRXLEIEANSAFDQYREMYF EGGVSSVYLWDLDHGFAGVLLIKKAGDGSNKIKGCWDSIHVVEVTDKSSGRAAHYKLTST AMLWLQTTKAGSGTMNLGGSLTRQTEMEANVGESSPHIANIGRMVEDMENKIRNTLNDIY ---------------------------------------DDGVS---DEKLATDEITIET KDDERLRKEPITTPYLTKFEIAGVIGVRAWHIAMGAPVAIETHGETNPKEIAKMELRAKK INLDIRRLLPNGSYEQHRVKDLIYTD---------------------------------- -------------GAIDRAALWPEVVRTRIRDTYAYFGGSLVFTAISRSPRMMNLMMRNS WVSLIGCMAVMMGTGMLCRSIPYQEGAKQLAWILHSCTVGAVIAPLTLLGGPLLIRAACY TAGVVGGLSTVAICAPSEKFMNIGGPLAMGLGVVFVSSIGTWFLPPSTVLGAGLYSVAVY GGLVLFGMFLLY------------------------------------------------ ----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXMDRPQPIPGVPPGLEYLVTLDQLLIHQQVEVLEAVVGWQCRNKYRIKNSLGQQVFFAA EESGVWMRQCCGSGRGFVLHITDNFGQEVIRVKRVFKCCAGCCWCANCSYELQVEAPVGT VCGYVRQMGWTARYMIRDAVLFIQGPCCIWNGICCTWDQKFKVVTQEVGIVSKQWSGLAK EAFTNAANFSATFPMDLD------------------------XXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX----VSRSVVCTDTKDQEEYQGEKPLYTYFCICGQMSLIIDCPLE KLPMRRRDNARVVDSAKHAHKITCESDDVVHLKRADGVEKQFRFKCKKCGLWLYYRHRNL ITYIVENALIKSGDSTTDVYKQIVEPKKVMVTKHTKNMGKFSSVTVSTVDEEEDEIEAKE IADSYAANARVIEKQLLRKGFSKRKLLEQAEDEAKKARPKGTLIDXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------KE KFGRLDVAVNCAGIGIAAVTYNVNKDRVHSLEDFLKVLTVNTGGSFNVIRLASQLMSTNQ PDASGQRGVIINTASVAAFDGQRGQAAYSASKGAIVGMTLPIARDLSNIGVRVVAIAPGL FDTPMLASLPEKVRSYLASTVPFPQRLGDPDEYAHLVQCIVENPLLNGEVIRLDGALRXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXMACLTQDEIIGRTKTVLQGLESLRTEHNQLLT GLLA---TVKDGSNSAAAEKAVFVKKSAEAMELGISEAQVVIALANHLQYIEAEKQKLRA QVRRLCQENAWLRDELANTQQRLQESEQKCATLSEEKVHLQFMAEM-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------KLAGKYDSEAEAEVLSWFKSLLNPGMREVEK QLRNGQLLVKLAKEIKARKMTLKANTLAAPFKQMENIQVFLNFCENYGVPKNALFQTVDL FEGRNMAQVLACIQQLGSEAQRNSFNGATIGPKPQEKNIRDFSEEQLRAGQLQAGTKQCA SQSMGGVRHAADIRADDMNKDSASIVSLQAGNKGASQAGMSMGGVRHAADIRADDALREG SGTVGLQMGSNKGASQAG---------------------------------------MSM GSVRHVADIRADDASEGMAATSLQYGSTAGASQTGMSMGGRRDI---------------- ----------------------------------------------------------MP EIHSFGIDPITCHSWNKERNQVALLNNDEVQLQSLKWTLKETLTDHTQRVTGIDWATKSN RIVTCAADRNAYVWPTLVVLGLNRAATCVKWSPKENKFAVGSGNRSIAVCSYDSDNNWWS SKKIKKPIRSTVTCLDWHPNNYLVACGSTDFKARVFSAYIKEVDEKPGPCNWGSKMPFAN LMSE---------------------------------------------------SSFVV AGYGCVPLRFNYNNG-ITFVSKLDGKKVTAMDRFKAMDSRAAALNSIHQNTITQLSIFAG GKEKCTKLTSVGTDGQLVIWDIKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXX---------------------------------------------------- ---------------------------------KTFCFCNDRDGCNSA--XXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------QRESDITKERIQKILSSGANVILTTGGIDDLCLKYFVEAGAMAVR RCKKTDLKRIAKATGGQLVSTLANMEGDETFEIAFLGQAEEVVQERICDDELILIKGPKA RTSASIILRGANDYMLDEMERSLHDALCVVKRVLESKTVVPGGGAVEAALSIYLENFASS LSSREQLAIAEFASSLLVIPKQLAINAAKDSTDLVAKLRAF------------------- ------------------------------------------------------------ ---DSENARLLASKTILNQFLVEDKDLTIQYDIYNVGASAALDVNLNDKSFPETDFDVVH GSLGVRWQRIGPSYNVSHIVILRPKKPGYFNFTSAELSYLSSESEAQLAYTSAPGEGVIA NFKDYDRKFSPHFMDWAAFAIMTLPSLGIPFLLWRSSKSRYDSAKTKKS----------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------QIHYKACYARVLDFRRKFIEAAQRYNELSYK TVIAEAERMTALRNALICTILASAGQQRSRMLATLFKDERCQQLPAYGILEKMYLDRIIR SSELHDFSDMLQTHQKAQTSDGSTILDRAVIEHNLLSASKLYNNISFDELGTLLEIPARK AEKIASQMITEGRMNGCID----------------------------------------- -----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXEYIIVETRGEKSNVGFIQLNRPKALNALCEGLMQEV NTALNEFEKNPSIAAVVLTGSEKAFAAGADIKEMENLTFRDVVMSDFLGDWTRITKFRKP IIAAVNGFALGGGCELAMMCDIIYAGEKAQFGQPEIVLGTIPGAGG-------------- ------------------------------------------------------------ ---------------------------------------- >Lumbrineris_zonata MADRKAVIKNADMAEDMQQDGVDVATQALEKYNIEKDIAAFIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSGLSTQLRQFQTSAVQRDIDQAAKYIGAGAATV GMAGAGAGIGSVFGSLVIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLILFAFM SHYKE-GKAPEATIHRIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKILRI TTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADMDQVM QFMEPAKMFCKDSIRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNII VXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----GRGGS AGGKFRISLALPVGAVINCADNTGAKNLYIIAVHGIKGRLNRLPAAGSGDMVMATVKKGK PELRKKAMPAVVVRQRKAIRRRDGVFIYFEDNAGVIVNVKGEMKGSAILGPVARECADLW PRIASNASSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXESI VTLRTRKFLTNRLLCRRQMVCDVLHPGKATVPKTEIREKLARMYKTTPDVVFAFGFRTQF GGGKTTGFALVYDSLDFAKKFEPKYRLARHGTRKQRKERKNRQKKVRGTKKAKVGSXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXMVRMNVLADALRSICNAEKRGKRQVLLRPCSKV IIRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDINMKDMEKWTTNL LPSRQFGYIVLTTSGGIMDHEEARRKHLGGKILGFFFXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXX-------------------------------------- ------------------------------------------------------------ ---------------------------------------QYTIEDGHSEWTSCVRFSPNT QNPIIVSAGWDKLVKVWNLTNCKLKTNHHGHNGYLNCVTVSPDGSLCASGGKDGQAMLWD LNEGKHLYTLEGGDIINSLCFSPNRYWLCAASGASIKIWDLEGKVVVDELRQEVISTNAE PP-CTCLAWSADGQTLFVGYTDNLIRVWQVSMATRXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXMSEEKKPGTEHINLKVTGQDGSVVHFKIKKNTPLRKLMS AYCDRTGVKMEAMRFRFDGQAINETDTPSQLDMEDGDSIDVFQQQTGGXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX----------------GAMDVNTALQEVLKTSLIHDGLARGLHEC AKALDKRQAHLCILANNCDEPMYVKLVEALCAEHGINLMKVDDNKKLGEWAGLCKIDKEG KARKVVGCSCVVVKDYGKDTQALDVLNEYFKSKRXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMDDYQTGEETAFVVDEVS SIIKEAVEGAIGGNSYQHNKVNKWTSTVVEQCLNQLTKLGKPFKYIVTCVIMQKNGAGLH TASSCFWDNTTDGSCTVRWESKTMYCIVSVFGLAIMFSANAKIVKPPGEKPDEFESSISQ ALLELEVNSDLKTQLRELYITAAKEIDVQGKKAIIVFVPVPQLRAYQKIQTRLVRELEKK FSGKHVVFIAQRRILPKPNRKTRRKNKQKRPRSRTLTSVHDTILEDLCHPAELVGKRIRI KLDGSRLIKVHLDKNQQTTVEHKVETFSAVYKKLTGKDVVFEFPDYVMXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXMKFNKMVTSSRRKNRKRHFNAPSHIRRKIMSSALSKDLRQKHNVRSMPIRKDD EVQVVRGHYKGQQVGKVVQVYRKKFVIHIERIQREKANGASVHVGIHPSKIVIVKLKMDK DRKRILERKAKSRQVGKHTEESIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNPEKLKQRIGGKGSARRKKKIVHRTATTD DKKLQTSLKKLAVNNIPGIEEVNMIKEDGQVIHFNNPKVQASLSANTFAISGHAETKAIT EMLPGILNQLGAESLANLKKLATNPGDIDEDDDEMPELVENFDEPSKGEXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXMGISRDHWHKRRKTGGRMAPLRKKRKYELGRPAANTKIGA RRIHTVRTRGGNKKYRALRLDAGNFSWGSEAQSRKTRIIDVKYNASNNDLVRTKTLVKNA IIEVDATPFRQWYEAHYAVPLGRKKGAKLSEAEEAVLSKRSKKTTKKYEERKKNSKVDPF LEEQFNSGRVLACVSSRPGRCGRCDGYILEGKELEFYLRKIKAKKGK-SLVLPEKFQHIL RVMNTNIDGREKIAFALTAIKGVGRRYSHVVCKKADIDLTKRAGELSEDEVDKLLTIMAN PRQYKIPDWFLNRQKDVKDGKYSQVMSNILDNKIREDLERLKKIRAHRGLRHYRGLRVRG QHTKTTGRRGRTVGVSKKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQTERAFQKQPTIFLNKKKPIIPRYVK NVGLGFKTPREAIDGNYIDKKCPFTGNVSIRGRILTGVVLKLKMVRTIVVRRDYLHYVRK YNRFEKRHKNISVHLSPAFRDAAIGDVVTVGECRPLSKTVRFNVLKVTKGSGSKKGFSKF ----PQQRKTFCKGKKCRKHTLHKVTQYKKGRDSLYAQGKRRYDRKQSGYGGQTKPIFRK KAKTTKKITLKMECSECKFRKQLAIKRCKHFELGGDKKKKGQMIQFMGRVIRSQRKGPGS IFKAHTKNRKGAAKLRAVDYAERHGYIKGVIKDIIHDPGRGAPLAKVVFRDPYRYKLRTE TFVAAEGMYTGQFVYCGKKATLQIGNILPVGVMPEGTIVCCLEEKTGDRGRLARASGNYA TVISHNPESKRTRVKLPSGSKKVMPSTNRAMVGIVAGGGRIDKPMLKAGRAYHKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGHASTVRRD-------------------------- -AKRTKKVGITGKYGTRYGASLRKTIKKMEXTQHGKYSCSFCGKDNMKRRAVGIWACGSC RKTVAGGAYVYSTTAAATVRSAVRRLREMKEMGRRPARCYRYCKNKPYPKSRFCRGVPDP KIRIYDLGRKKARVDDFPLCVHLVSDEFEQLSSEALEAARICANKYLVKTCGKDAFHLRI RVHPFHVVRINKMLSCAGADRLQTGMRGAFGKPQGTVARVKIGQPIMSVRAREGSQADVV ESLRRAKFKFPGRQKIYASKKWGFTKWTHEDYERLRKEGKLIPDGVTVQYFPNHGPLAAW KARQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXQTALAFKLVLVGDGGVGKTTFVKRHLTGEFEKKYVATLGVEVHPLSFHTNRGEIKF NVWDTAGQEKFGGLRDGYYIQGLCAIIMFDVTSRITYKNVPNWHRDLVRVCENIPIVLCG NKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLVGDPNLEFVAMPA LAPPEIQMDPKMAQIYEQELQIAQQTALPDDDEDLXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXX-TARYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVR GKDLVVLGVEKKAVAKLQEDRTVRKIALLDDHVAMAFAGLTADARILINRSRIECQSHKL TVEDPVTLEYITRYIATLKQRYTQSNGRRPFGLSALIIGFDGTPRLYQTDPSGTYHEWKA NAIGRSAKTVREYLEKYYTAEVASDDETIKLALKALLEVVQSGSKNMEIAIMRRNEPXQM MESEEVEKYIQ----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX >Macrochaeta_clavicornis MTDRKAVIKNADMSEDMQQDAVDCATQALEKYNIEKDIAAFIKKEFDKKYNPTWHAIVGR NFGSYVTHETKHFIYFYLGQVAVLLFKSGLNTQVRQFQTSALRRDIDQAAKYIGAGAATV --------------XLVIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLILFAFM SHYKEAGKAPEATIHRIRITLTSRNVKSLEKVCSDLIKGAKDKNLKVKGPVRMPTKILRI TTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX X-ARQMSKKRKFVADGVFKAELNEFFTRELAEDGYSGVEVRVTPTRTEIIILATRTQSVL GEKGRRIRELTAVVQKRFKFPEGTVELYAEKVSTRGLCAIAQAESLRYKLIGGLAVRRAC YGVLRYIMESSAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGEPTNDYVDTAVRHVLLRQ GVLGIKVKIMLPWDPTGKMGPKRHLPDNVSIVDPKDEVIPEHPYSEQKGAKMSKRGRGGS AGGKFRISLALPVGAVINCADNTGGKNLFVIAVHGYKGRLNRMPAAASGDMFVATVKKGK PELRKKVIPAVVIRQRKPIRRKDGLVIYFEDNAGVIVNNKGEMKGSGITGPVAKECADLW PRIASNASSIRKGKVQKVQLGPQVAEGENVFGVAHIFASFNDTFVHITDLSGKETLVRIT GGMKVKADRDEASPYAAMLAAQDVAERCKTLGINALHIKLRATGGNRTKTPGPGAQSALR ALARSGMKIGRIEDVT------------------MGKPSGLRTARKLRLHRRDQRWNDLD YKKAHLGTRWKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP RDGCLNYVEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKEKKERPRSXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--RV PLVCSKTFATPRRPFEKERLDQELKLIGEYGLRNKREVWRVRYTLAKIRKGARELLTLDE KEPKRLFEGNALLRRLVRIGVLDETKMKLDYVLGLRLEDFLERRLQTQVFKLGLAKSIHH ARVLIRQKHIRVRKQVVNIPSFIVRLDSQKHIDFSQRSAYGGGRPGRVKRRNAKKGTGGG AD--------------------------AAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVGEAREELNRMLNEDELRD AVLLVFANKQDLPNAMNAAEITDKLGLHSLRNRNWYIQATCATSGDGLYEGLDWLSNQLK NQKMPLARDLLHPTLDEERRRCKLKRLVKSPNSFFMDVKCPGCYKITTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRRKQHMTRMNVLADALKSICNAERRGKRQVLIRPCSKV IIRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVAMRDLEKWTTRL LPSRQFGYLVMTTSGGIMDHEEARRKHLGGKILGFFFMGRMHAPGKGISGSALPYRRSVP TWLKLTPDDVKEQMYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKAKGLAPD LPEDLYHLIKKAVAIRKHLERNRKDRDAKFRLILVESRIHRLARYYKTKRVLAPNWKYES STASALVAVAEMPEVKLFGRWSPEDVQINDISLTDYIAVKEKSAKYLPHSAGRYQVKRFR KALCPIVERLTSSLMMHGRNNGKKLMTMRIVKHAFEIIHLLTGENPLQILVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGARESAFRNIKTIAECLADELINAAK GSSNSYAIKKKDELERVAKSNRMSEQMTLRGTLQGHGDWVTQIAATPQFPNIILSASRDK SLIMWKLTRDVSYGVPQRSMRGHGHFVSDVVMSSDGQFALSGSWDHTLRLWDLSTGQTTR RFVGHDKDVLSVAFSADNRQIVSGSRDRTIKLWNTLGVCKYTIEDGHNNWASCVRFSPNT QNPIIVSSGWDKCVKVWNLTNCKLKTNHIGHSRVLNCVTVSPDGSLCASGGMDGQAMLWD LNEGKHLYTLDGGSTINALTFSPNRYWLCAATGPSIKIWDLEGKIVVDELRQEVITANAR APSCISLAWSADGQTLFAGYTDNLIRVWQVSMAARXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXX---------DHLNLKVTGQDGSVVHFKIKKNTPLRKLMS AYCERTGVKMGSMRFRFDGSPINETDTPSQLEMEDGDSIDVFQQQTG-XXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXMSDAEGDDVPTPAVVGGSMDVNTALQEVLKVALIHDGLARGLHEC AKALDKRQAHLCILANNCDEPMYVKLVEALCAEHGINLIKVDDNKKLGEWAGLCKIDREG KARKVVGCSCVVVKDYGKDTPALDHLNEYFKSRKXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMYSAQAKIIKPRGEKPDEFESTISQ ALYDLEMNSDLKAQLRELFITGAKEIDISGKKAIVIFVPVPQLKSFQKIQSRLVRELEKK FSGKHVVFIAQRRILPKPTRKMRRKNKQKRPRSRTLTAVHDCILEDVCYPSEIVGKRIRI KLDGSRIMKVHLDKTQQTNIEHKLETFTGVYKKLTGKDVQFEFPEYAL------------ ----------GKDGDKEWIPVTKLGRLVKDLKIKTLEEIYLFSLPIKEHEIIDFFLG--- ---------------------FKAFVAIGDYNGHIGLGVKCSKEVATAIRGAIVLAKLSV MPVRRGYWGNKIGKPHTVPCKVTGKC----------------------XXXXXXXGIEDC YTCARGQTATLGNFAKATYSAISKTYSYLTPDLWKETVFHKSPYQEFTDYLMKMSGGHEV LALKEEDVTKFLACSTHLGSTNADFQTMQYVYKCKPDGVFIINLRKTWEKLLLAARAIAA IENPSDVAVISARPYGQRAILKFAQHVG-------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------MKFNKMVSTARRKNRKRHFNAPSHVRRIIMSSPLSKELRQKHTVRSMPIRKDD EVQVVRGHYKGQQVGKVVQVYRKKFVIHIERIQREKANGQSVNVGIHPSKVVIVKLKMDK DRKAILERKARGRQGGKHTEESIQSPSATSVGGTVRQRKAPAAGAGGAGMWRFYTEDSPG IKVGPVPVLVMSLLFIASVFMLHIWGKYNRGKKNKKKKTVTNEVVTREYTVNIHRRLHGV GFKKRAPRAIKEVRKFVEKAMGTPDVRIDTRLNKHLWSKGIRNVPFRIRVRLSRKRNEDE DSPHKLYTLVTYVPVAAFAGLQTVNVES-------------------------------- ------------------------------------------------------------ -------------------------------------------------RHCNKVFLIDF GLAKKYRDNRSRQHIPYREDKNLTGTARYASINAHLGIEQGRRDDMESLGYVLMYFNRGS LPWQG------------------------------------------------------- ------------------------------MNPEKLKQRIGGKGSARRKKKVVHRTATTD DKKLQSTLKKLAVNPIPGIEEVNMIKEDGQVIHFNNPKVQASITANTFAVTGHAETKAIT EMLPGILNQLGAESLSNLKKLASKTEDID-EDDEVPELVENFDEASKEE----------- ---------HLRVHFKNTRETALAVKRMHLRRAVTFLKNVCEKKECVPFRRYSGGVGRCA QAKNWRSTQGRWPKKSAEFLLQLLKNAESNAEFKGLDTDHLVIEHIQVNRAPQMRRRTYR AHGRINPYMCSPCHIEVILGEREMAIAKP-KKKVSQKKLKKQKM----XXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXMGISRDGWHKRRRTGGRRVPIRKKRKFEMGRPSANTKLGP RRVHLVRTRGGNTKYRALRLDFGNFSWGSEAHTRKTRIIDVVYNASNNELVRTKTLVKNC IVQIDATPFRQWYEAHYALPLGRKKGAKLTAEESEALNKR-------------------- ------------------------------------------------SLVIPEKFQHIL RVMNTNIDGRRKVPFAMTAIKGIGRRYSHIVCKKADVDVTKRAGEMSEEETEKIITIMTN PRQYKIPDWFLNRQKDCKDGKFSQVMANFLDNKLREDLERLKKIRAHRGLRHYWGLRVRG QHTKTTGRRGRTVGVSKKK-SGSDSDSDDDVPDLEEMAAAAGLPEELVSKAKQSRSEKKA RKAMSK------------------------------------------------------ -----------------------------------------------------MGRVRTK TVKKGARVIIEKYYTRLTLDFHTNKRICEEIAIIPSKKLRNKIAGFVTHLMKRIQRGPVR GISIKLQEEERERRDNYVPEVSAIEEVDPDTKEMLKLLDMGNIQGLQLLQPQSNQXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------------- ----------------------------------------------------TLMELGIS PIVTSGLIMQLLAGAKXXXXXXXPKDRALFNGAQKLFGMVITIGQAIVYVMTGMYGEPAE IGAGVCLLIIIQLFVAGLIVLLLDELLQKGYGLGS------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------XXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX MVNVPKARRTFCKGQKCRKHTLHKVTQYKKGRDSLYAQGKRRYDRKQSGYGGQTKPIFHK KAKTTKKIVLKMECTECKYRKQLPIKRCKHFELGGDKKKKGQMIQ-MGRVIRSQRKGPGS IFVAHVKKRKGAARLRAVDYAERHGYIKGVVRDIIHDPGRGAPLAKVAFRDPYRYKTRME TFIATEGLHTGQFLYCGKKASLQIGNILPIGQMPEGTIISCLEEKTGDRGRLARTSGNYA TVISHNPDTKRTRVKLPSGTKKLIPSANRAMVGIVAGGGRIDKPMLKAGRAYFKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGMASTVRRDTSAGRKVGLIAARRTGRLRGSK---- -----------GKYGTRYGASLRKGIKKMEVSQHSKYTCSFCGKDAMKRQVVGIWKCKSC RKCVAGGAYVYSTTAAATVRSAVRRLREIKEMGRRPARCYRYCKNKPYPKSRFCRGVPDP KIRIYDLGRKKARVDEFPLCIHLVSDEYEQLSSEALEAGRICANKYLVKHCGKDAFHCRV RPHPFHVVRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQPIMSVRSRDQHKDHVI EALRRAKFKYSGRQKIYQSSKWGFTKWPRDKYEGMRAEGRLVPDGVNVQYKPDHGPLKAW YKA-KVTKILGRTGSQGQCTQVRVEFLDDSNRSIIRNVKGPVREGDILTLLESEREARRL RMTKGTSSFGKRRNKTHTLCRRCGGRSYHIQKKVCGRCGYPAKRMRKYNWSEKAKRRRTQ GVGRMSHMKKVFRRFRNGFREGTVAKKIKG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------DLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHSNGLTLVARAHQLVMEGYNWCHDRNVVTIFSAPNYCYRC GNQAAIMELDDALKYSFLQFDPAPRRGEPHVTRRTPDYFLMGAYKYMQELYRKKQSDVMR FMQRIRTWHYRQLNSVHRASRPSRPDKARRLGYRAKQGFVIYRVRVRRGGRKRPVPKGAT YGKPTNQGVNELKNQRSHQGIAEERVGRKCQALRVLNSYWVAHDATYKFFEVILVDPSHK AIRRDPKTQFLCTANAKHREMRGLTSANKKSRGLGKGHSFNNTIGGSRHANWKKHNRVVM RRKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGKSSKMLQHINYRMRCTL LDGRVFIGTFKAFDKHMNLILGDCDEFRKVKPKSSKQREEKRVLGLVLVRGQNLVSMTVE GPPPPEEGISRVPLPGQA-GPGMGRAAGRGVP---------------------------- --------------------GKTTFVKRHLTGEFEKKYIATLGVEVHPLVFHTNRGPIRF NVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTARITYKNVPNWHRDLVRVCENIPMVLCG NKVDIKDRKVKAKAIVFH------------KSNYNFEKPFLWLARKLVGDPNLEFVAMPA LQPPEVEMDPNMAAKYEQELQIAQQTALPEDEDELXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXLGFAENFALSGCAAIISKTAAAPIERVKLLVQNQDEMIKAGRLDRPYTGVIDCTT RTFRTEGLLPFWRGNLANCLRYFPTQALNFAFKDKIKALFKSSKKDSYGVAFGKNIASGG LAGAMSLCFVYSLDYARTRLANDAKSGAKRQFNGLIDVYSKTMKSDGIAGLYRGFVISCV GIIVYRGCYFGFYDTLKPIIIGEEANLMASFALGYVVTISAGLVSYPIDTIRRRMMMTSG QAVKYKGSVDCFLQIMKTEGFMSLMKGAGANILRGVAGAGVLAGFDTFKEVYIQWR-XXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSIGV PIKVLHEAEGHIVTLETNTGEVYRGTLVEAEDNMNCQMSKITCTYRDGRVAQLENVYIRG SKIRFLILPDMLKNAPMFKKVGAGRGKSAILRAAARGRGRSSGGRGRGGMQNEAGEYVDM YIPRKCSASNRIIAAKDHASIQINFAEVDETTGRMTGQYKTYAICGSVRRMGESDDCLVR LAKKDGIIAKMPRGPRKHLKRLNAPSHWMLDKLGGVFAPRPSTGPHKLRECLPLVVFLRN RLKYALTYTEVKKILHQRLVKVDGKVRTDKCYPSGFMDVITIDRTKENFRLIYDVKGRFT VHRITEEEAKYKLCKVRKVTVGPKGVPFLTTNDGRTIRYPDPLVKIHDTIQVXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXX-------------------------------------- ----------------LQEDRTVRKIALLDDHVALAFAGLTADARILINRARVECQSHRL TVEDPVTLEYITRFIAQLKQKYTQSNGRRPFGLSTLIIGFDGTPRLYQTD---------- ------------------------------------------------------------ ---------------------------SGGGGGDKKDDKDKKKRYEPPVPTRVGKRKKKV KGPDAATKLPQVTPYTKCRLKQLKLERIKDYLLMEEEFIKNQERLKPQEEKNEEERSKVD DLRGTPMSVGSLEEIIDDNHAIVSTSVGSEHXXXXXXFVDKDQLEPGCSVLLNHKVYAVI GVLQDDTDPMVTVMKLEKAPQETYADIGGLDTQIQ------------------------- ------------------------ATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPS IVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSKGDVKVIMATNRIETL--- ------------------------------------------------------------ ----------------------------------------EQKRYSPFQNPTTVDYALAR VDDLVNWARKSSLWPLTFGLACCAVEMMHFAAPRYDMDRFGVVFRASPRQADCIIVAGTV TNKMAPALRKIYDQMTEPRWVISMGSCANGGGYYHYSYSVVRGCDRIIPVDIYVPGCPPT AEALLY---------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----KKQKK TIESINARLALVMKSGKYHLGYKQTLKTLRQGKAKLIIIANNTPPLRKSEIEYYAMLAKT GVHHYNGNNIELGTACGKYFRVTTLSITDPGDSDIIRNMPASXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-KIDLCA FSGLKIYPGHGKKAVKIDGRTFQFINAKCEASHYMKRNPRKISWTVLYRRKHKKGQTEEI TKKRTRRTQKFQRAITGASLNDIMAKRNQKPEVRKAQREQAIRAYKEKQKQKEMSKPRVG GKRMKLNISYPATGCQKLIEIEDEKKVRSFYEKRMSSEVDAGCLGDEWKGYVVRISGGND KQGFPMKQGVMTTGRVRLLLSKGHSCYRPRRTGERKRKSVRGCIVDANLSVLSLVIVRKG EQEIPGLTDKTIPRRLGPKRASKIRKLFNLSKDDDVRQYVVRRPVNPKTKAPKIQRLITP AVLQRKRRRRAIIKKRNVRKREEAATYQKLLAQRMKEAKERKMERRRSAS---KVKAKDL RGKKKEELMQQLEELKTELSQLCVAKVTGGAASKLAKIHVLRKSIARVWTVINQTQKENL RKFY-------------------------------------------------------- --------------------------------------------FHRVIKDFMIQGGDFT RGDGTGGRSIYFADENFKLKHYGPGWLSMANSGKDTNGSQFFITTKTTQWLDGKHVVFGK ILEGMKVIRKIEKSQTDRDRPSADVEIANSGLLDPFEPFSTPKEAADEXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------EETKYGGCEGPNAMYVKLV SSDGHEFIVKREHALTSGTIKAMLSGPGQFAEHETNEINFREIPSHVLQKVCMYFTYKVR YTNSSTEIPEFPIAPEIA------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGHPPLSVDAV RERVLLVLKLYDKITPEKLTLDSHFMNDLGLDSLDQVEVIMAMEDEFGFEIPDQDAERLV RPADVVQYVCDKEDVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSMRRP FDPAAHDLEPSFRLTRFADLKGGCKVPQDVLLKLLEGLNQGQESEQAQFGYGAPAPKIGI GMDACVTPLRHGGLSLVQTTDFFYPLVDDPYMMGKIAASNVLSDLYAMGVTDCDNMLMLL GVSQKMSEKERDVVVPLMIRGMKDCAEEAGTSVNGGQTVINPWLTVGGVATTVCQPNEFI MPDNAVVGDVLVLTKPLGTQVAVNAYQWLDQPDRWNRIKLVVSEDDVRKAYQRAMFSMAR LNRTAARLMHKYNAHGATDITGFGLLGHANNLASIQKNEVGFVIHNLPVIAKMA------ ------------------------------------------------------------ ------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXTAAFDARFPNQNQTRNCWQNFVDFHRCHKIDDYE PCDYFKRVYQSLCPNEWTSKWDDQMENDEFAGKI-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------VANRTDACFIRVIGSELVQKYVGEGARMVRELFEMART KKACIIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFD---------------- ------------------------------------------------------------ -----------------------------------------------MGKEKIHINIVVI GHVDSGKSTSTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITI DIALWKFETEKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKNGQT REHGLLAFTLGVKQMIVGVNKMDNTEPPYSEARFNEITKEVSAYLKKVGYNPKAVAFMPI SGWHGDNMIKMPWFKGSEIVKVQTLYAALDSIVPPSRPTDKALRLPLQDVYKIGGIGTVP VGRVETGILKPGMVVTFAPCNLTTEVKSVEMHHEALTEALPGDNVGFNIKNVSVKEIRRG YVAGDSKNNPPIQTETFDAQVIVLNHPGQINAGYAPVIDCHTAHIACKFQDLKEKVDRRS GKKLEDNPKFVKSGDAAIVEMKPSKPICVEQFSEFPPLGRFAVRDMRQTVAVGVIKSVQK KDVTGGKTTKSAQKAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPKQ IMEIKDFLLTARRPDAKSVKIKKNVKFKVRCSRYLYTLVVSEMEKAEKLKQSLPPGLAVK ELKMSKLSRDLLRESVGTLLDKKRKFTESVELQIALKNYDPQKDKRFAGTIKLKHIPRPK LRVCMLGDQQHCDEAKANDVPCMDSEALKKLNKNKKLVKKLAKKYDAFLASDTLIKQIPR ILGPGLNKAGKFPTMLTHNEGMVGKIDEVRATIKFQMKKVLCLSTAVGHVNMSQEELVGN VLLAINFLVSLLKKNWQNVRALHIKSTMGPAHRIY------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------DCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT LFS--------------------------------------------------------- ------------------------------------------------------------ -----------------------------------VLDDKNVRRRFRASNYQSTTRVKPF ICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDEL PAEFKLYLPVQG-MTDPIVPTLLEPFDEDNEIHIRIQQRNGRKTLTTVQGISSEFDLKKI VRAAKKEFACNGTVVEHPEYGEVIQMQGDQRTKISNFLKGVGLEDRIKIHGFXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX------ALARQLPKAAKQKNSIGAGFVAARKFNTSAEISSILEDRILGAAGAELEET GRVLSIGDGIARVYGLKNIQAEEMVEFSSGLKGMALNLEPDNVGIVVFGNDKLIKEGDVV KRTGAIVDVPVGEELLGRVVDALGNTIDGKEAIRDPERRRVGTKAPGIIPRISVKEPMQT GIKAVDSLVPIGRGQRELIIGDRQTGKTAVAIDTIINQKRFNEGQNEKSKLYCIYVAIGQ KRSTVAQIVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCAMGEFFRDNGKHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDDFGGGSLTALPVIE TQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQMKAMKQVAG SMKLELAQYREVAAFAQFGSDLDAATQQLLNRGVRLTELLKQGQYVPMAVEEQVAVIFSG VRGHLDKMDPAKITEFEEEFLAHLLSSQQALLKQIREDGQITEPTEAKLKEVTTTFLAGF XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPLILDARGHLMG RLASITAKSLLQGQRVVIVRCEEINISGSFYRNKLKYLDFLRKRHNTNPKKGPFHHRAPS KVFWRVVRGMLPHKLNRGKEALGRLKVFEGIPPPYDKKKRLVCPSALKVLRLKARR---- -----------------------------------------------------------A GDIDKGKKIFVQRCAQCHTVESGGKHKTGPNLSGLFGRKTGQAPGFSYTEANKKKGITWG QDTLWAYLENPKKYIPGTKMVFAGLKKKNERADLIAYLEDSTK----------------- ----------------------PEQASDFYAEHYGKLFFPSLVAYMSSGPIIAMVIAREK AISYWRELIGPTNAIKARETHPDCLRAIYGTDDQRNGLHGSDSYSSA------------- ----------------VNPTLLKGLTELCKQKPKDPVIWLADWLLENNPNKPKVKMFEAR LVQGSLLKKVLEAVKDLLNEATWDCNGQGMSLQAMDSSHVSLVALQLRSDGFDTYRCDRN ISLGINLGSMSKILKCASNDDAITIKAGDNADTVTYMFESPNGDKVSDYEMKLMDLDTEH LGIPETDYSCVVKMPAGEFQRICRDLSQIGESVVICCTKEGVKFSASGDLGTGNIKLAQT ASVDKEEEAVVIEMNEGVTLTFALRYLNYFTKASPLSPQVTLSMSADVPLVVEYKIGDMG YVRFYLAPKMEDDAD-KSVAAHQTTHRDIRGRIVAVIGAVVDVQFDEDLPPILNALEVQE RSPRLVLEVAQHLGENTVRTIAMDGTEGLIRGQVCVDTGTSISIPVGPETLGRIINVIGE PIDERGPVNSKAHASIHADAPEFVEMSVEQQILETGIKVVDMLAPYAKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVISLKDNTSKVSLVYG QMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIA ELGIYPAVDPLDSTSRILDHNVVGMEHYNIARGVQKILQDYKSLQDIIAILGMDELSEDD KLTVSRARKIQRFLSQPFQVAEVFTGSEGKLVPLKETIKGFKMILEGELDHLPEVAFYMV GPIEEVVDKARRLAEDKMLMPKKNRVLIYENLFKEGVMVAKKDVHAPKHPDLDVPNLHVI KALQSLKSRGLVTEQFAWRHYYWYLTNEGIQYLRDFLHLPPEIVPSTLKRQAMAEDRQAY RRGGGGDKKADVGAGAQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX MTNTKGYRRGTRYMFSRQFRKKGVIPLSKYMKLYRRGDIVDIKGDGAVQKGMPHKAYHGK TGRVYNVTQHAVGVIVNKRVHGKILPKRVNLRIEHVKHSGCRLDFLNRVKVNEKLKKEAK TKPNCKRQPVQPRGAHFVSQRYNKPERIAPIKWEFVAXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----------------KEVKGTYVSIHSS GFRDFLLKPELLRSIVDCGFEHPSEVQHECIPQAILGMDVVYQ----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------PPSYADLG KSARDLFSKAYNYGFYKLEVKTKADNGVQFTTNANSNHDSQKFAGSLEXK---------- --XWNTDNTLGTEITIEDQLVKGLKLSFDTNFAPQSGKKSGKIKTAYKQEHVHATCDVDF DFAGPTIHGSAVLGHSGWLAGYQMSFDKSKLAKSNFGVGYQTGDFTLHTAVNDGSEFQGS IHQKVRDNLQTGVNLNWTAGSNATKFGLAALYTPDKDTKFRAKVNNASQIGLSYQQKLYD GATVTLSTLIEGKNFNQGGHKLGMGLEFEAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXMGKFMKSGKVVLVLSGKYAGRKAIIIKNYDEGTQEKPYGHAMVA GIDRYPRKVTKRMGKKRIKVRSKIKPFVKVFNYNHLMPTRYTVVNLDKKTVNKDAFRDAA LRRKARRETKAKLEERYKSGKNRWFFQKLRFERSFIMVKPDGVHRGIVGEIIKRFEGRGY KLVAMKMMWSSKEHLQTHYADLKDKPFFPKLIEYMSSGPVVPMVWEGDVVRMG------- ----------------------------------------------------------KS APKPVKTQQKAKEKALRAKKAVLRGVQQKRSRKMRTSVSFRRPKTLRLAREPKYPRKSVP SRPRLDRFKIMKYPLTTESAMKKIEDNNTLVFIVDRRSNKHTIKLSVK------------ ------------------------------MPSKQRMRLANEKMSKNVAQRGNVPKSLKP SEEKYSVGPWLLGLFVFVVCGSAIFQIIQSIRMXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX------------IPCDFIYEDDQCVAFKDLNPQAPTHFLVIPR KPISQLSADEPLLGHLMNVARKVAHETNGFRLVINDGKDGAQSVYHLHLHIMGGRQMGWP PXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXMAARPLISVYNEKGERTKRTLKLPAVFKAPIRPDIVNVVHADMKCNSRQPYAV SMKAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTRTWRRWNRR INTNQRRYALSSAIAASGIPALVMSKGHLVEQIPEIPLVISDKAQGIKKTKEAVTMLRKL RAWQDIEKVKNSRRFRAGKGKMRNRRRIQRRGPVVIYNQDSGLCHAFRNIPGITLLKVEK LNLLKMAPGGHLGRFCLWTESAFKKVDSIFGTWKTPSKVKQGYRLPIPKMTNTDLQRILK SEEIQSVIRPTKPAQKRKVMKKNPLKNKQAMAKLNPFEQVRKKTAQRQKARQQALDQKRG VATVDKPGKARPRGLLQ------------------------------------------- ----------------------------------------IESQMIVKDNRRYYLDLKEN SRGRFLRVAPP-QNRVNIAIPAQGMVEMRDTIAELLKEF--------------------- -----------------------------------------------XXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------------SRRHRGKV KAFPKDDPAKPVHLTAFISYKAGMTHILREVDKPGSKSHKKEVVESVTILEAPPMIIVGV VGYIETPRGLRGFKTVFAEHLSEECKRRFYKNWYRCKKKAFTKYAKKWQDDAGKKEIEKD LSKIKKYCKVVRVIAHTQIKQLKQQQKKAHIMEIQLNGGSVEDKVEWAREHMEKQVPVKE VFAQDEMIDIIGITKGHGFKGVTSRWHTKKLPRKTHKGLRKVACIGAWHPARVAFSVARA GQKGYHHRTEINKKIYRIGNGIHTKDGKVVRNNASTDYDQTEKTVTPLGGFPHYGEVNHD FVMIKGCCVGPKKRVITLRKSLLVHTKR-------------------------------- ------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXX---------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------E GYGLSWNPNVNGNLLSASDDHTICLWDINAAPKEGRVVDAKTIFTGHTSVVEDVSWHLLH ESLFGSVADDQKLMIWDTRSQNHNKASHTVDAHTAEVNCLSFNPYSEYILATGSADKTVA SW-------------------------------------------------GEEQSAEDA EDGPPELLFIHGGHTAKISDFSWNPNEPWVVCSVSEDNIMQVWQMAENIYNDEEPDAAAS ELEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVPETLLKRRKRRNQAAKQKRKVIFKRAE SYIKEYRIKERDEIRLAREARKQGQFYVPPEAKLAFVVRTRGINGIHPKPRKVMQLLRLR QINNGTFVKLNKATISMLRIAEPYITWGYPNLKSVRELIYKRGYGKTKGQRIPLTDNATI ENRLGENGVICIEDLIHEIFTIGPSFKSVNNFLWPFKLNTPNGGWRKKNNHFVDGGDYGN REDKINVLLRRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSKAHPPELKKYM DKRLSLKLNAGRIVSGVLRGFDPFMNLVVDEAVEECKTGERNDIGMVVVRGNSIVLLESQ ERIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------D IKVIAATNRVDILDPALLRSGRLDRKIEFPSPNEEARARILQIHSRKMNVSSEVNFEELA RCTDDMNGAQCKAICVEAGMIALRRGAVELGHEDYMDAILEVQA----------XXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXKPAYKVADISLAEWGRKEIAIAENEMPGLMMMRRKFGESKPL KDARIAGCLHMTVQTAVLIETLLELGAEVQWSSCNIFSTQDHAAAAMAKKGVPVYAWKGE TDEEYMWCIDQTIVFSDNRPLNMILDDGGDLTNLVHEKYPQFLEGIKGLTEETTTGVHNL YKMMSKGTLKCPAINVNDSVTKSKFDNMYGCRESLLDGIKRATDVMIAGKVAMVAGYGDV GKGCAQSLRAFGARVLIAEIDPINALQASMEGYEVTTVDEAVKEARIFVTATGCKDIIRP QH----------------XXXXXXKWLNENCAKKEEVKPQVDRYTMKNGRHLILLAEGRL VNLGCAMGHPSFVMSNSFTNQVLAQIELWTKAKDYPLGVHFLPKHLDEAVAEAHLEHLGV KLTKLSDEQAEYLGLPATGPFKPDHYRYADEQEQEPVQTIQEPLDLIRLSLDERIYVKMR TDRELRGRLHAYDQHLNMILGDVEETVTSVEIDEETYEEIYKST---------------- -------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------- --------------------------------------------THTAVVPLDLVKCRLQ VDPEKYGNIIKGFRVTLQEAGVRELGKGWSPTLIGYSMQGLCKFGFYEVFKVFYSNLIGE EKTYLWRTSLYLAASASAEFFADIALCPMEAVKVRIQTMPGFASNLREGFPKIMNQEGIR GFYKGIVPLWGRQIPYTMMKFACFERTVEALYRFVVPKPRADCTKSEQLVVTFTAGYIAG VFCAIVSHPADTLVSQLNKAPGS------------------------------------- -----------------------------------------PAALAFALDTLLTSMCLHT HWGLAGVCKDYIHLSTVAFGALLYFNYTDIGFANAVRTIYTELXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--- ---------------------------------EEEAVPLPNVNAAILKKVIQWCTYHKD DPPPPEDDENKEKRTDDISSWDSEFLKVDQGTLFE--------------XVTCKTVANMI KGKTPEEIRKTFNIKNDFTPAEEEQVRKENEWCEEKNKRLTKGGKKGGKKKVVDPFTKKE WYDVKAPSMFNIRQIGKTLVTKTIGTKIASEGLKGRVFEVSLADLQSDEVPFRKFRLIAE EVQARNVLCNFHGMTLTTDKLRSMVKKWQTLIEANVDVKTTDGFMLRVFCIGFTKKRQNQ IKKTCYAQSAQVRNIRKKMVDIMTREVSANDLKDVVNKLIPDSIGKDIEKACQGIFPLHD VYIRKVKILKK-----------------------------------------XXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XX---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------EKDYKKQFDD AGVWYEHRLIDDMVAQAIKGNGGFVWACKNYDGDVQSDVVAQGYGSPGLMTSVLMCPDGK TIESEAAHGTVTRHYREHQKGNPTSTNPVASIFAWTRGLEHRATLDGNLDLARWCQTLEK ACVDTVDSGKMTKDLA-----------------------------XXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------- ------------------------------------------------------------ ------------------------------------------------WDDETDMKEVER LIREIETDGLLWGAAKLVPLAYGIKKLQINCVVEDDKVGTDYLEEEITKFEDFVQSVDIA AFNKIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------KLKECETVLVNDFFLVACLDDFIDNARLFIF ETFCRIHQCISIDMLAQKLNMTPDEAEKWIVNLIRNARLDAKIDSKLGHVVMGNTANSPY ------------------------------------------------------------ ---------------FEFNVGVGQVIKGWDEGVAGMSVGERCVLTCTPDYAYGERGAGGV IPPNATLQFDVELI---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXLLCLLGAALADPTIYFEERFWESRWVESTHKGGEQ GKFEWTAGKFYGDADKDKGLQTSQDARFYGISAKFDKPFSNEGKTLVVQFTVKHEQNIDC GGGYVKV----------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------EVDNPDYEADDALYKYEDFGAIGFDLWQVKSGTIFDNILFTDDEDHAEAVGTE LWEATKDAEKTMKDEQDE--------------------------XXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTFLFTSESVGEGHPDKICDQV SDAVLDAHLKQDPNAKVACETAAKTGMIMLLGEVSSKANVDYQKVVRETIKYIGYDDSSK GFDYKTCNVLSALEEQSPDIAQGVHEGXXXXNIGAGDQGLMFGYATDETEECMPLTVVLA HKLNAKMA---------------------------------------------------- ------------------------------GRFVIGGPQGDAGLTGRKIIVDTYGGWGAH GGGAFSGKDFSKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVAEPLSIFVSSYGT GVKSDDELLKII----------------------------------------------XX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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ALRVTDRARGRILKSGGEIMTLDQLAMKSPKGQNTVLIQGPRKAREAQRHFGPAPGVPDS RTKPYV---------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------- -------------------------------------------QILDGELFDFDVEVGPI LEVLVGKTVEQSLLEVMEEEELANLREQQRAFEELRNAELVEQQRLEEQERRHREEKERR MKQQKEILRKERETADKIAARAFAQSYLSDLVPSV------------------------- ------------------------------------MKARGELKEYKVIGRAMPTEKNRV PKLYQMQIFATDKITAKSRFWYHCNQLRKMKKTTGEIVLCQQIHDSSPTKIKNVGIWLRY TSRSGIHNMYREY----------------------------------------------- ---------------------------------AQDQMKAYWEKNIKRPNSPWIIYWPHV PMMSSLTHRTTGICMGVALYAISFGLLAKSGDFNSLVATMKS----------AKTICAFP LIYHFCSGTRHLTWDAGYAYELATQYKTGYTVAGTFAYWXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------------- ------------------------------------------------------------ -----------------------------------------------------------A SQSMGGSRHVSDILVDDMSKEGAGIIGLQAGNKGASQSGMGTGS-RDLAKSGAEAMSKEG AGVIGLQAGSNKGASQSGMRTG-TRDLAQSGAEAMSKEGSSVIGLQAGSNKGASQSGMRS GP---------------------------------------RDLATSGTGDMEGQSMIGL QAGTNKGASQSGMRSGP-RDLAASGAGEMESKGVINLQYGTNQGATQSGMTSGGRRDI-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------DATVKTQFLPYTACLWVNPTSIVV AGHDCCPMMFAFDGQAVRFSGKLDSQKFSAMKHFRSLD---------------------- -----------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----ETRSAMMEGTGTLEMQLEATKRKSAEVRSQRSQLKRIEDLSAAMEDRLILDNRYTE HSTVGLAQQWDQLDQLGMRMQHNLEQQIQAMQSSGVKEEALREFSMMFKHFDKDKSGKLS HQEFKSCLRALGYDLPMVEEGQTDPEFDAILDIVDPNRDGLISLQEYMAFMISRETENVQ SSSEVEAAFRALTSG--------------------------------------------- --------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIDRDDRDNPQ LVSVYVNDIYHYLWELERQEVNGRMRGILVDWLVQVHLRFHLLQETLYLTVAIVDRFLQE EVSRRKLQLVGVTAMLIASKYEEMYAPEIGDFEYITDNAYSKADIRKMECLILKTLDFNL GRPLPLHFLRRNSKAGEVDATKHTLAKYLMELTITEYDMCHTPPSEIAAAALCLSCKVLD WTDTLSHYSKYSREDLQPTIRQLANLVLKKLTAIKTKYQSSKLMRIASMPELKSQVVKDL AXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------AKMKLG VELLVNDPTKLEDMRKRESDITKERIQKILATGANVILTTGGIDDLCLKYFVEAGAMAVR RCKKVDLKRIAKATGGQMVVTMANLEGDEVFEASMLGAADEVVQERICDDELLLIKGPKA RSAASIVLRGANDFMVDEMERSIHDA---------------------------------- -----------------------------DATDLVAKLRAYHNTSQTKSDREDLKWAGLD LHEGVVRDNKKAGVLEPTISKIKSLKFATEAAITILRIDDMIKLAPEQKGGGGYQEALRS GQL-DDRARLMISKNVLNQMLVEGKDLTVQYDIYNVGGRAAMNVHLTDSSFSGDDFEVVK GNLDVTWQRIVPGSNVSHVVILRPLRAGYVNFTSAEVSYLPSEEEPQIGYTSAPGEGGIL NFKEYDRKFSPHLLDWGAFVI----------------------------XXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX >Magelona_bekeleyi MTDRKAVIKNADMSEDMQQDAVDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYF------------------RLLQTSAIHRDIDQAAKYIGAGAATV GVAGSGAGIGSVFGSLVIGYARHPVLKQQLFSYAILGFALSEAMGLFCLMMAFLILFAFM SHYKESGKAPESNIHRIRITLTSRNVKSLEKVCADLIRGAKDKQLKVKGPVRMPTKILRI TTRKTPCGEGSKTW------IHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADMDQVM AFLEPAKTFSKDSIRLVKRCTKPDRKEFQKIAVATAIGFALMGFIGFFVKLIHIPINNII VMATQVSKKRKFVQDGVFKAELDAFLTRELAEDGYSGVEVRVTPNRTEIIILATRTQNVL GEKGRRIRELTALVQKRFNFSEGGVELYAEKVATRGLCAIAQCESLRYKLIGGLAVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPTHDYVDTAVRHVLLRQ GVLGIKVKIMLPWDPTGK---------------------------------MSKRGRGGS AGGKFHMSLALPVGAVMNCADNTGAKNLYVIAVHGIGARLNRLPAAAVGDMVMATVKKGK PELRKKVMPAVVIRQRKSFRRKDGVFIYFEDNAGVIVNNKGEMKGSAITGPVAKECADLW PRIASNASSIRKRAAKVVSLGPQVAEGENVFGVAHIFASFNDTFVHVTDLSGKETIVRVT GGMKVKADRDEASPYAAMLAAQDVASRCKELGITALHIKLRATGGNRTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRLMGKPRGLRTARKLKTHRREQRWHDKD YKKSHLGTRWKSNPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKK------ ---------------------------------------------------------EGI VTLRTRKFLTNRLLCRKQMVVDVLHPGRPTVSKTEVREKLSGMYKTTPDVVFAFGFRTQF GGGKTSGFALIYDSLDFAHKFEPKHRLIRHGTRKQRKERKNRQKKVRGTKKAKVGQMGKI PMNYTKTSQTPRRPFEKERLDQELKLIGEYGLKNKREVWRVRYALAKIRNNARELLTLEE KHPRRMFEGQALLRRLIRIGVLDEEKMKLDYVLGLKIEDFLERRLQTQVLKLGLSKSIHH ARVLIRQRHIRVRKQVVNVPSYMVRLDSQKHIDFASNSPYGGGRPGRCARKNSKKNKGGG DA---------------------------------------------------------- ------------------------------------------------------------ --------------------------------RNWYIQATCATSGDGLYEGLDWLSNQLK NQKMPLAKDLLHPSLDEEKRRCKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRRKQH-----ITAGALRSICNAEKRGKRQVLIRPCSKV IIRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVHIQDIEKWTRNL LPSRQFGFLVLTTSGGIMDHEEARRKHLGGKMLGFFFMGRMHTPGKGISQSALPYRRSVP TWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKAKGLAAD IPEDLYHLIKKAVAIRKHLERNRKDKDSKFRLILIE------------------------ ------------------------------------------------------------ ---------------------------------------LLTGENPLQVVVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREAAFRNIKTIAECLADELINAAK GSSN------------------MGEHLQLITTASGHGDWVTQLATTPDHPDVLLSSSRDQ SLIVWQYDPNGDKLTAMKRLSGHGGFVSDCVISSDGQFALSSSWDKTIRLWDLEYGATTR QFKGHTKDVLSVAFSGDNRQIVSGSRDKTIKLWNTLGVCKYTIEDCHDHWVSCVRFSPST NNPVILSCGFDKVVKVWNLSNCKLKTNHIGHTGVLNTVTVSPDGSLCASGGKDGKLKLWD LSDGKHLYTLSANGCISSLVFSPNRYWLLEAANTTLKIWDLESKSVVDTIEPEVVS--GK PPMAISLAWSNDGQVLFSGWTDNKIRVYQVA----------------------------- ------------------------------------------------------------ ----------------------DVPMILVGNKCDLEDERVVGKLARQFNCAFLETSAKSK INVNEIFYDLVRQINKKNPETXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXMSDAEGDDVPVAPPNDGPMDINTALQEVLKTALIGDGLARGLHEC AKALDKRSAHVCILANNCDEAMYVKLIEALCSEHGINLIKVDDNKKLGEWAGLCKIDKEG K----------------------------------------------------------- ------------------------------------------------------------ --------------------------------KDLRNDEQTKRELMKMKQEPVRPDEGRA MAEKINAYAYLECSAKTKEGVREVFETATRAALQTKKKKK--XXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------- -------------------------------------------------------ELEKK FSGKHVVLIAQRRILPRPTRKNRTKNKQKRPRSRTLTSVHDSMLEDLCFPSEIVGKRIRI KLDGSRLIKVYLDKNQQTTIEHKCDTFTAVYRKLTGKDVVFMFSE---DRGGFRGGFGGR GRGRGRGRGRGKD-EKEWVPVTKLGRLVKDLKIKSLEELYLFSLPIKEFEVIDFFLGTAL KDDVLKIMPVQ------------------------------------------------- ------------------------------------------------KKLLHMAGIDDC YTSASGQAATLGNFAKATYAAIAKTYGYLTPDLWKETVFTKSPYQEFTDYLAK------- ------------------------------------------------------------ ------------------------------------------------------------ ----QPVREAPYVNIPVIALCNTDSPLRYVDVSIPCNNKGVHSIGLMWWLLSREVLRLRG TISRDVPWDVMVDLYFYRDPEEAEKE---------------------------------- -------MKFNKMVTSSRRKNRKRHFNAPSHVRRKIMSSPLSKDLRQKHSVRSIPIRKDD EVQVVRGHFKGQG-GKVVQVYRKKFCIHIERIHRDKANGASVHVGIHPSKIVILKLKMDK DRKRILERKAASRQQGKHTEESIAPASATSVGSTVRQRKTVASGAGAAGMWRFYTEDSPG IKVGPVPVLVMSLLFIASVFMLHIWGKYTR-KKEGKKKAVTNEVVTREHTINLHKRIHGV GFKRRAGRAIKEIRKFAEKMMGTPDVRIETRLNKHIWSQGIRNVPFRVRVRLARKRNEDE DSPNKLYTLVSYVPVATFKGSQTVNVES-------------------------------- ----------------------------------------WYGEKDYNVLVMDLLGPSLE DLFNFCSRRFTMKTVLMLADQMIGRIEYVHNKNFIHRDIKPDNFLMGIGRHCNKVFLIDF GLAKKYR----------------------------------------------------- ------------------------------------------------------------ -----------------------------------LRPRIGGKGTARRKKKVVHRTATTD DKKLQSSLKKLSVNNIPGIEEVNMIKEDGQVIHFNNPKVQASIAANTFAITGHAETKQIT DMLPGILNQLGTDSLANLKKLATATGDIDDDDDEVPDLVENFDEASKGEXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRKTGPKPELTEE QKQEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKKK-------------------- ------------------------------------------------------------ --------------------MGISRDKWHKRRKTGGRMAQVRKKRKFELGRPAANTKIGT RRIHTIRTRGGNKKYRAMRLDTGNYSWGSEGVSRKTRILDVVYNASNNELVRTKTLVKNA IVVIDAVPFRNWYESHYALPLSRKKGAKLTPEEEARLNKRSKSAQKKFEVRKKTAKVEPS LEEQFASGRLLACVSSRPGQCGRCDGYILEGKELEFYMRKIKAKKGKMSLVVPEKFQHIL RVLNTNIDGRTKISYALTSIKGVGRRYSNVVCKKADVDISKRAGELTDDEVEKVITIMQN PRQYKVPDWFLNRQKDIKDGKYSQVLSNALDNKLREDLERMKKIRAHRGLRHYWGLRVRG QHTKTTGRRGRTVGVSKKKGSGTESDSDDSAPELEDLAQAAGLPEELVSKAKQSRSEKKA RKAMSKLGLKQVAGVSRVTIRKSKNILFVINRPDVYKSPASDTYIVFGEAKIEDLSQQAT VRAVDQFKTEEEVDEAGVEAKDIELVMSQANVSRGKAVKALKNNQNDIVNAIM------- ------RVIIEKYYPRLTLDFHTNKRVCEEIAIIPSKKLRNKIAGFVTHLMKRIQKGAVR GISIKLQEEERERRDNYVPETSALEEVDPLTKDMLKMLDMANMQGLQVTQPMPTGXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------- ------GESGDRLTRASKVLEQLTGQTPVTSKARYTVRSFGIKRNEKIAVHCTVRGAKAE EILERGLKVREYELRRNNFSGTGNFGFGIQEHIDLGIKYDPSIGIYGLDFYVVLGXPGFN INKRKR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------PIHAFLYIVFMLGSCAFFSKTWIEV SGSSAKDVAKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIG SGTGILLAVTIIYQYFEIFVKEQSEMGGMSTLLFQTERAFQKQPTVFLNKKKTLLPRHVK SIGLGFKTPREAIDGHYIDKKCPFTGNVSIRGRILTGIVVKMKMQRTIVIRRDYLHFVRK YERFEKRHKNLSVHLSPCFRDVSPGDIVTVAECRPLSKTVRFNVIKVTKGTGSKKGFQK- MVNVPKQRKTFCKGQKCRKHTLHKVTQYKKGKDSVFAQGKRRYDRKQSGYGGQTKPIFHK KAKTTKKIVLKMECTECKYKKQLAIKRCKHFELGGDKKKKGQMIQF-------------- ----------------AGDYAERHGYIKGVVKDIIHDPGRGAPLATVVFRDPYKYKLRKE LFIACEGMSTGQFVYCGKKATLTIGNVMPVGSMPEGTIICNVEEKSGDRGKIARVSGNYA TVISHNPDTKRTRVKLPSGSKKVLPSTNRAMVGIVAGGGRIDKPMLKAGRAYHKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGMASTVRRDTSAGRKVGLIAARRTGRLRGSKQ--- -AKRTKKVGIVGKYGTRYGASLRKTVKRMEISQHSKYTCQFCGKDAMKRKAVGIWSCSKC RKVVAGGAWVYSTTAAATVRSAVRRLRDMKEMGRRPARCYRYCKNKPYPKSRFCRGVPDP KIRIYDLGRKKAGVDEFPCCIHLVSDEYEQISSEALEAGRICANKYLVKHCGKDAFHLRV RVHPYHVLRINKMLSCAGADRLQTGMRGAFGKPQGTVARVDIGQTVLSVRTRVNNSERVI EALRRAKFKFPGRQKIYVSNKFGFTKYTQEVYKQYLAEGKLIPDGSNVQYKPDHGPLKLW MMRV---------------TQVRVEFLDDSNRSIIRNVKGPVREGDILTLLESEREARRL R-TKGTSSFGKRHNKTHTLYRRCGGRYYHIQKKTCSRCGYPAPRMRKYNWSEKASRRRTQ GVGRMRHMKVVFRKFRNGFREGTVPKPKKG------------------------------ ------------------------------------------------------------ --------------------------------------GFYDECLRKYGNANVWKYFTDL FDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDKKE------------RAHQLVMEGYNWCHDRNVVTIFSAPNYCYRC GNQAAIMELDDALKYSFLQFDPAPRRGEPHVTRRTPDYFL-------------------- ------------------------------------------------------------ ------------KNQRSLQGVAEERAGRKCGGLRVLNSYWVAEDSTYKYFEIIMVDPHHK AIRRDPGLQWICKSTAKHREMRGLTSANRKSRGLGKGHKFHRTIGGSRRTNWKRLTNQSM RRKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGKSSKMLQHINFRMRCTL QDSRIFIGTFKAFDKHMNLILGDCEEFRKMKSK-NKGREEKR------------------ ------------------------------------------------------------ ----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------HSRKMNLTRG INLHKIAEMMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFELAVAKVMQKDSKK---- -----LGFAENFALSGAAAVISKTAAAPIERIKLLVQNQDEMIKQGRLKEPYKGVIDCTV RTYKKEGIMPFWRGNLANCIRYFPTQALNFAFKDK------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------DRITLIRGNHESRQITQV YGFYDECLRKYGSITVWRYCTEIFDYLSLSAIIDGKV----------------------- ------------------------------------------------------------ ------------------------------------------------------------ --LPPEVNRILYVRNLPYKITGEEMYDIFGKYGAIRQIRVGNTPETKGTAFVVYEDIFDA KNACDHLSGFNVCNRYLVVLYYQSNKAFKKMDTEKKKQD----------------XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMQNEGGDFVDM YIPRKCSASNRIIHAKDHASIQINLAEVDPTTGRMTGSHKTYAICGAIRRMGESDDCLGR LAKKDGIIAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXMSARYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVR GKDIVVLGVEKKAMAKLQEDRTVRKIALLDEHVAMAFAGLTADARILINRARVECQSHRL TVEDPVTLEYITRYIAQLKQRYTQSNGRRPFGLSTLLVGFDGTPHLYQTDPSGTYHEWKA NAIGRSAKTVREFLEKHYSDEVQSEKESIKLALKALLEVVQSGSKNMEIAVMRR------ ---------------------------------------------EPPVPTRVGKKKRKM KGPEAANKLPQVTPYTRCRLKLLKLERIKDFLLTEEEFIKNQERLKPQEEKHEEERSKVD DLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDALEPGCSVLLNHKVHAVV GVLGDDTDPMVTVMKLDKAPQETYADIGGLDTQIQEIKESVELPLTHPEY---------- ------------------------------------------------------------ ------------------------------------------------------ETLDPA LIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTLAEDVNIDDYVMAKDDLSGADIKAICT EAGLLALRERRMKVTNEDFKK--------------------RKPYSPFQVSNKVDFALAR LDDLLNWARKSSLWPLTFGLACCAIEMMHFAAPRYDMDRFGVVFRASPRQADVIIVAGTL TNKMAPAFRKVYDQMPEPRWVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPS AEALLYGILQLQKKIKRMKNVQMWYRK--------------------------------- ------------------------------------------------------------ -ISFTTSKIGSLVDINNSKDPEGLRCFYYLVQDIKCLVFSLISLHFKIKPIMVAQKKVKK AIESINSRLALVMKSGKYVLGYKQTLKTLRMGKAKLVIIANNTPPLRKSEIEYYAMLAKT GVHHYNGNNIELGTACGKYFRVTTLSITDPGDSDIIRSMPAAXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKLEICS FSGFKIYPGHGKRHVKVDGKVFNYISKRCERSMDQKRNPRNVSWTVLYRHQHKKGTTQDV VKKRTRRTVKHVRAVTGASLTDILAKKNQTPEVRKAQRDQAIRAAKEKKRAVDAPKARVG GKR--------------------------------------------WKGYQVRVSGGND KDGFPMKQGILTNGRVRLLLSKGHSCYRPRRDGERRRKSVRGCIVDSNLSVLSLVIIKKG DEDIPGLTDNTIPRRLGPKRANKIRKLFNLSKSDDVRQYVVRRPLPAHTKAPKIQRLVTR IVLQRKRHRIALKKRRSAKKREEAAEYAKLIAQRLKEAKEKKLERKRSSSHSKKVKAKEL RGKKKEDLLKQLDELKTELSQLRVAKVTGGAASKLSKIRIVRKSIARVLTVIHQTQKENL RKFYKPTDLRRKKTRAIRRQLTRHEASMKTKKQERKERLYPMRKFAVKKTAKGPKVTDKV FFDITIGGEPAGRIVIGLFGKTVPKTAKNFKTLAEGTQTFKGSKFHRVIKDFMIQGGDFT RGDGTGGKSIYFADENFKLKHYGSGWLSMANAGKDTNGSQFFITTKITPWLDGRHVVFGK ILEGMSVVRTIENSEKDRDRPVKDVIIADSGSIPVDQPFAVTKDAAEERRIKVNLRYTID CTHPVEDGILDPASFEKYLVERVKVDGKTSNFKNKLILASDVPFSKRYLKYLTKKYLKRH NLRDWLRVVANNHDSYELRYFQINNEEEDDDDDNXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---PLTIDSV RERVLLVLKLYDKVDAEKLNVDSHFTHDLGLDSLDHVEVVMAMEDEFGFEIPDADAERMF KPADIVQYVCDKQDVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------ ----------------------GCKVPQEVLLKLLEGLQ-AQDPEQVHFQYVAAVPRIGI GMDSCVTPLRHGGLSLVQTTDFFITAGDDPYMMGKIACANVLSDLYALGVTECDNMLSLL ASSNKMTKKKK------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------VEGYFMNIDAHAEECFFDKVTSGTKMSLMFEVAEGGFLDI DVKIMGPDGKNIYTGERESNGKYTFAAHMDGTYQYCFSNKMSTMTPKIVMFSMDIGEKKK ARQNKLEEMIXXXXXXXXXXKHEQEYMAVRERIHRSINDNTNSRVVLWSFFEALVLVAMT LGQIYYLKRFFEVRRVVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXX------------------------------------------------------- ------------------------------------------------------------ -------------------KRAQSWCHSKGDIPYFETSAKEAINVEQAFQTVAKNALAQE TNVELYNEFPDQIKLT-------------FDARFPNQNQTRNCWQNYVDFHRCHKVEDYE PCGYFKRDYESLCPNAWVEKWDEQFEAGNFAGKIXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------REVSSYIKKVGYDPVTVGFVPI SGWSGDNMLNMGWYKGFTIEKGETLLEALDLIDEPSRPTDKALRLPLQDVYKIGGIGTVP VGRVETGILKPGMVVTFAPPAISTEVKSVEMHHEALTEALPGDNVGFNIKNVSVKEIRRG NVCGDSVRDPPRQTGNFTAQLIILNHPGQINPGYAPVLDCHTAHIACKFSELKEKIDRRS GKKIEDNPKFVKNGDSAIVEMVPQKPMCVEAFSEYPPLGRFAVRDMRQTVAVGVIKSVTK KD-ASVKQTKAAQKAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSYAYLF KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES FRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLEARR DVKKEK------------------------------------------------------ --------------------MTKGRTELGDVTVHNIKQLKRLNQVVFPVTYNDKFYKDVL EVGELSKLAYFNDIVVGAVCCREHKKE--------------------------------- --------------------------------------------------------MPKQ IMEIKEFLLTARRKDARAVKIKKNVKFKVRCSRFLYTLVINDNEKAEKLKQSLPPGLAVK ELKMSKVTRDMYTECIAAVLQKKRKFTETVELQIVLKNYDPNKDKRFSGXM---HVPRSK YRVCILGDQRHIDEATALGVPSMSADDLKKLNKNKKLVKKLAKKHDAFLASETLIKQIPR LLGPGLNKAGKFPTVLSHGEAMTGKINEVKATIKFQMKKVLCLAVAVGNVEMTPDQLLQN TNLAVNFLVSLLKKNWQNVRALYIKSTMGPAQRLY------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------RAMEQIRRIMRPTDVPDQGLLCDLL WSDPDKETMGWGENDRGVSFTFGSEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAKKKKFPYGGINSGRPITPPR------ ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXM--TDIQNLQDPFADAQDIHIRIQQRNGRKTLTTVQGINPKYDLKK- ----------------------------------------------------XXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----DVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQIKAMKQVAG SMKLELAQYREVAAFAQFGSDLDQATQNLLNRGVRLTELLKQAQYVPMAVEEQVAVIFAG VRGHLDKVDPSKIVAFEKEFLQHLRSSQQEVLADIRAKGMISEESEKKLKDIVLNFLSGF XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXMPKVRKSRKPPPEGWELIEPTLDELDQKMREAETEP HEGKKK------------------------------------------------------ ------------------------------------------------EYAQVTKMLGNG RLEALCFDGVKRLCHIRGKLRKKVWINQSDIILVGLRDYQDTKADVIQKYSPDEARSLKA YGELPDHVDVEE--NDDVTFSEIEDIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLMAK PKSEMTPEELAQRENEEFNTGPLSVLTQSVK----------------------------- ------------------------------------------------PIVIDARGHLLG RLASIVAKTTLQGQRIVVVRCEEINISGSFYRNKLKYLNFLRKRMNTNPSKGPYHLRAPS KIFWRTVRGMLPHKLARGKAAMDKLKVFEGIPPPYDKEKRMVVPSALRILRLKPRRKFCV LGRLSHEVGWKYQGVIATLEAKRKTKSNKYYKNKKADNLLRSKATKIAKQQAVIEGFGYA GDATKGAKIFKQRCAQCHNVEKGGKHQTGPNLHGLIGRKTGQAPGFSYTEANKSKGITWQ KETLFTYLENPKKYIPGTKMIFAGLKKKGDRAHLIAYLEEST-XXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXX-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------AKAHGGYSVFAGVGERTREGNGLYHEMIEGGVISLTDKSSKVALVYG QMNEPPGARSRVALTGLTVAEYFRDKEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTKK---TSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIS ELGIYPAVDPLDSTSRILDVNIVGLEHYTVARGVQKILQDHKSLQDIIAILGMDELSEDD KLT-------------------VFTGSPGKLVPLKDTIKGFEMILKGELDHLPEQAFYMV GAIEEVVAKAERLAEDKMIITKQNRNAIYENLFKEGVMVAKKDPYG-QHSELSVPNLQVM KALQSLKSRDYVKEQFAWRHYYWSLTNEGIQYLRDYLHLPSEIVPATLKRQASSDDRQSY RKGIGPDKKADAGAGAN------------------------------------------- -----------------------------DLNDDGKVEIHEFAATLSITP-----EEAKQ AFSDSDTDDDGFLTKDEL------------------------------------------ ------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX -TNTKGYRRGTRYMFSRKFKKHGPIALSKYFICYKRGDIVDIKGDGAIQKGMPHKSYHGK TGRVYNVTQHALGVIVNKRVRGKILAKRINIRVEHVKHSNCRLDFLKRVKENEEKKKEAR EKVQLKRQPAQPRPGHIVRTKHNLPQMVEPIPYEFIA----------------------- ---------------------MFKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAICPAQAITIEAETREDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEY STETREELLYKKEK-----------------------MATQPKVSKPDGKNNHENDKDQQ EAIEQIDEVQNEIDRLNESASEEILKKEK------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------KKLTKQEELLLQDFSRNVSTKSSALFYGNAFIVSAIPIWLFWR IHQMDLYIFFVIMTLVSSYLVAMAYRNVKFVLKHKIALKRGDAVSREVMKRVADDKKMSK QEKEERILWKKNEVADYEATTFSIFYNNALFLMLVILASVYILRSLSPTLNYSLSMGVAS GLLALFSTSSKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- -----------------------------------------EIRTVLLSIQALLSAPNPD DPLANDVAEQWKVNEAQAIENARQWTRMYAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPTYGDLG KSARDLFNKGYNYGSFKLECKTKASNGVEFKTNGNSNHDSGKVGGGLETKYKWSDYGLTF LEKWNTDNILGTEITIEDQIAKGLKLSFDTSFAPQTGKKSGKIKTAYKKE---------- ------------------------------------------------------------ ----------------------------------------------------SYQQKVRD GVTLTLSSLLDAKNFNQGGHKVGVGLDLEA------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------TAGVDKYIGES ARLIREMFGYARDHQPCIIFMDEIDAIRRFSEGTSADREIQRTLMELLNQMDGFDALGQV KMIMATNRPDTLDPALLRPGRLDRK----------------------------------- --------------------------------------------------------MTDS VFSVISKFYSEYMENTPKKLKIIDSYLLYIMLTGIVQFVYCCLVGTFPFNSFLSGFISCV -------------------------------------------------XXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXMGKFMKAGKVVLMLGGRYAGRKAIIVKNYDDGSSDKPYSHALVA GIDRYPRKVTKRMGKNKIKQRSKIKTFVKVANYNHLMPTRYSVVNLDKASVNKEAFRDPA LRRKARRETKLKFEERYKTGKNRWFFQKLRFXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-- ---------KSKDKALKAKKAVLRGVHDKRQRKKRTTVHFRRPKTLHLPRTPKYPRKSTP RRSRLDQFRIVKFPLTTESAMKKIEDNNTLVFIVDKRANKPNIKFAVKKLYDIDVSKVNT LIRPDGEKKAYVRLAPDYDALDVANKIGII------------------------------ -----PVGPWLIALFVFVVCGSAVFQIIQSIRMXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMIRFI LIQNRAGKTRLAKWYMHFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFQKRK--------- ------------------------------------------------------------ -----------------RDTIFGKILRGEVPSKFIYQDEQCVAFRDIMPQAPVHFLVIPR KSLSNLTSDEQLLGHLLAVARK-------------------------------------- -MGGLISYFAGLFGSKERRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVQYKN LKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSMDRDRIGISKQELVSMLEEEELKSAT LCVFANKQDIEGAMTVT------------------------------------------- -XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXRLYCKAVFTGFKRGLRNQHENTALLKIDGVISKKETDFYLGKRCAYVYKA KKKTACPGHDKPSRLRVIWGKVTRPHGNSGSVRAKFRKNLPPSAIGKRIRVMMYXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------- ------------------------------------------------------HEERKT KQKNNDEVPEGAVPAYLLDREGQSRAKVLSNMIKQKRKEKAGKWEVPLPKVKGMGENEVF KVVKKEK----------------------------------------------------- ------------------------------------------------------------ -------MAARPLISVYSDKGEATGTNVTLPAVFKAPIRPDIVNFIHSEMKKNSRQPYAV SEPAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRR INVNQKRYALCSAVAATGIP---------------------------------------- -----------------------------------------------------------R LNLLKIAPGGHVGRFCIWTESAFKRLDGLYGTWKKQSKEKTNYNLPMPKMTNNDLSRLLK SDEIQKVIRRPIKSHKRHELKKNPLKNMAIMQRLNPYAAVQKRNAIRKAEKQKILDKKRG IAPAEAQGKARPRKVTK------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------MRISESNFRTAITIPERSWARFRDIMADFVEKXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------LPKKRSKRHRGKV KAFPKDDRTKPVHLTCFLGYKAGMTHIVRDVDRPGSKVNKKEVVECVTIIETPPMVIVGL VGYIETPSGLRSFKTIFSQHLSEECRRRFYKNWFKSKKKAFTKYSKKWEDQSGLKEIEKD FAKMKKYCKVIRVIAHTQMKLVGKHQKKADIMEIQVNGGTVGDKVQWAREQMEKQVSIHS VFSQDEMIDVIGVTKGKGFKGVTSRWHTKKLPRKTHKGLRKVACIGAWHPSRVAYSVARA GQKGYHHRT-----------------------------------ITAGGGFPHYGXVNQD FILLRGGCAGPKKRVLTLRKSLLVQTKRVAHEKIELKFIDTSSKFGHGRFQTLEEKRAFI GPLKKD----------------------------------TAGDNYSANVMVDGKPINLG LWDTAGQEDYDRLRPLSYPQTDVFLICFSLISPASFENVRAKWFPEVSHHCPNTPIILVG TKLDLRDDKDTLEKLKEKKLSPIMYPQGLAMAKEIGAVKYLECSALTQKGLKTVFDEAIR AVLCPKIVTKKKK-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVVRPEEK DYSIHRLILGTHTSDEQNHLLIASVQLPNDNAQFDASHYDSEKGEFGGFGSVSGKIEIEI KINHEGEVNRARYMPQNPCVIATKTPSSDVLVFDYTKHPSKPDPSGECHPELRLKGHQKE GYGLSWNPNLNGHLLSASDDHTICLWDINTTPKEGRCIEAHTIFTGHTSVVEDVSWHLLH ESLFGSVADDQKLMIWDTRSNTTNKPSHTVDAHTAEVNCLSFNPYSEFILATGSADKTVA LWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQSAEDA EDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEEPDTPAS ELEMPAPSRARVYADVNTHRPREYWDYESHVVEWGQQDDYQIVRKLGRGKYSEVFEAIN- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------AVPETLLKKRKQAAEKNVEKRKVMFKRAE QYIKEYRLEERDQVRMARMARKDGNFYVPPEPKLAFVMRIRGINGIHPRPRKVMQLFRLR QINNGTFIRLNKATLHMLRLAEPYITWGYPNLKSVRELIYKRGFAKVDGNRMPLTDNAII EKALGKFGIICMEDLIHEIFTVGPHFKEANTFLWYFKLNTPSKGWRKKNNHFVDGGDYGN REDKVNELLKRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXMAVRYDLAVGMNKGHKVTVQKPRPSRRKGTQTKHVKFVRDIVR EVCGFAPYERRTMELLRISKDKRALKFCKKRLGSHVRGKRKREEMQNVIQMMRKT----- ------------------------------------------------------------ --------------------------TTAVELAIPELDGKTAKMYRGGKICLTDHFKPLW ARNVPKFGIAHAMALGLGPWLAVEVPDLIEKGIITHK----------------------- --------SSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNYKEEPIRVGE IVVFKVEGREIPIVHRVLKV---------------------------------------- --------------------------------------XXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------N IKVIAATNRVDILDPALLRSGRLDRKIEFPVPNEEARARIMQIHSRKMNVSSDVNFEELS RCTDDFNGAQCKAVCVEAGMIALRREATELKHEDYMDAILEVQAKKK-------XXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXX------------------------------------------ --------------TAGLIETLTELGADVTWSSCNIFSTHDHAAAAIAKTGVPVYAWKGE TDEEYLWCIEQTLVFPDGKPLNMILDDGGDLTNLAQKR---------------------- ------------------------------------------------------------ -------------------------LQAAMEGYEVTTMDEACKYGRIFVTTTGCKDIITG KHFSEMTEDAIVCNIGHFDTEIDVAWLNKTAKEKVNIKPQVDRYTMPSGRHLILLAEGR- ------------------------------------------------------------ ----------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------- -----------------------EFGSSKYYALCGLGGILSCGITHTAVVPLDLVKCRIQ VDPAKYGNIFNGFKVSVKEGGVKGLALGWAPTFFGYSMQGLCKFGFYEVFKVFYSD---- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------GFMGMWQGLFPRIIMIGTLTALQWFIYD SVKVAFRLPRPPPPEMPESLKKKL-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------GVLKVGQEIEVRPGIVSKDQEGKLTCKPIFSRIV SLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGHVLGAVGALPEIYTELDISYYLLR RLLGVRTEGDKK------------------------------------------------ ----------------------------MAELLLDSNIRFWVFLPIVVITFLIGIIRHYV TIVLASEKKIEVQQIADSQTLIRSRVLRE------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------DKPGAASEDEIRHHFGLHGQTTGRGNVAR SELRPMELFMCSVLKRQGYGEGFRWMAQYINXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPN IKLQSSDGEIFEVDVEIAKQSVTIKTMLEDDEDEEEAVPLPNVNAAILKKVIQWCTYHKD DPPPPEDDEKRKK----------------------------------------------- ------------------------------------------------------------ ---ITAGSMFAMRQIGKTLVTRTQGTKIASDGLKGRVFEVSLGDLQNDEVVFRKFKLIAE EVQGKQVLTNFHGMGMTTDKLRSMVKKWQTLIEADVDLKTTDGYLLRLF----------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------ESTGRGKSKSVELEDVKFHQCVRLSRFEN DRTISFIPPDGEFELMSYRLNTHVKPLIWVESVIERHAHSRVEYMIKAKSQFKRRSTANN VEILIPVPPDADSPKFKTTVGSCKYAPDQNSVVWTIKSFPGGKEYLMRAHFGLPSVLSED PEEKPPIHVRFEIPYFTVSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRT------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------IYKIPHCVPISAHHKWNFDDLLEKMWTYLQLVRIYTKPKGQLPDYNSP VVLKDGHTSVEDFCEKIHKTILKEFKYALVWGSSVKHQPQKVGKEHILNDEDVVQIVKRX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPNFPPISGEKL MGKSEMRKVPVPANRYTPLKENWMKIFSPVVEHLHLQIRFNLKSRNVEIKTCKETKDISS LQKGADFVRAFILGFEVEDALALVRLDDLYLESFQITDVKPLKGDHLARAIGRVAGKGGK TRYTIENVTRTRIVLADSKIHILGSFNNI------------------------------- --RIKVANPVVELDGDEMTRIIWEKIRERLILPYLDVDIKYFDLGLPYRDQTNDQVTIDS AHAIQKYNVGIKCATITPDEERVEEFKLKKMWLSPNGTIRNILGGTVFREPIMTSNVPRL VPGWNQPITIGRHAHGDQYKATDYVVKGAGKFELVFTPSDGRPERMEAYNFEN-GGVLMG MYNTDDSIRGFAYSCLNFALQKKWPLYMSTKNTILKRYDGRFKDIFQEIYDSEFQDKYEK AGIWYEHRLIDDMVAQALKSSGGFVWACKNYDGDVQSDIVAQGYGSLGLMTSVLVTPDGK TVEAEAAHGTVTRHYREHQKGNPTSTNPVASIFAWTRGLEHRGNLDDNKDLVRFCQQLEG ACVDTIESGLMTKDLAGCIHGIKNVKPEHYQYTMDFLESIAQALDXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------- ------------------------------------------------------------ ------DDDIDLFGSEAEKIKAERLAAYAAKKSPVLIAKSNIILDVKPWDDETDMVEMEK MVRSVETDGLLWGAAKLVPVGYGIKKLQICCVVEDDKVGTDFLEESITAFEDYVQSVDVA AFNKIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXX---LLGAVFCD--IIFEERFWEDRWVESKYKGSEQ GQFKWTAGKFYGDADLDKGIQTGQDARFYGISHKFDEPITNEGKTLVVQFTVKHEQNIDC GGGYMKLYPSDLEQKDLHGDSPYHIMFGPDICGPGTKKVHVIFTYKGKNLLTKKDIRCKD DVMTHLYTLIVRPDNTYEVKIDNKK----------------------------------- ----------------------------------------------------EKIDNPAY KGKWIHPEIDNPEYEADDKIYSYSDIGAIGFDLWQVKSGTIFDNVLITDSVEEASTQAGD ILIRMEE-EKRQKEAKDEEDRKK---------------------XXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXX--------------------------------------------------- ------------------------------------------------------------ ---------------------GEVTELTPVETENPMGGYGKTVSHVIIGLKTAKGTKQLK LDPSIYESLQKEKVEVGDVIYIEANSGAVKRQGRSDTYATEFDLEAEEYVPLPKGDVHKK EK---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------GPQRSVEGWILFITNVHEEALEDDIIDKFGE YGEIKNLHLNLDRRTGFLKGYALVEYETFSEAQAATEALNGSEILGQKINVDWCFVRGPV KHKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------TFDVRAR KMSKRAIKTLNIVLDELDLHWIPINKSWRLNERMYGGLQGLNKSETAAKHGEDQVKIWRR AYDIPPPTLEVSDPRWPGHDARYQYLDRQLVPVT-------------------------- ------------------------------------------------------------ -------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXX-----------------------YLRLLVKLYRFLARRTNA KFNRIILKRLFMSKNNKPPISLARVVRNMKKTGRENKTCVIVGTVTDDIRIFDVPKLKIC ALRVTGSARSRILKAGGEIITFDQLALKAPKGQNTVLIQGPRHARDAYRHFGRAPGVPHS STAPYVRSKGRKFERARGRRAS-------------------------------------- -----------------------------------DDYVIESIGEFLSELEGSAQALEHI HSNEVVKTVQAFLKR--------------------------------------------- ------------------------------------------------------------ -------------------------------------XXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSAHEEMKQFWNKNLQRPNSPWWIYKPHL PMLTSLCHRMTGIAMGVAFYAFSISVFVAPGDFPSYVEFLKNLEL---LLFPVKTVVAFP LVYHYINGIRHLTWDAGHGYELKTQYKTGTVILASIAYWXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXX------------------------------------------------------- ------------------------LKVLSVASGECVQQLKGHKNTVTSVKIHPKIFILFS AS---------------------------------------------------------- ------------------------------------------------------------ -------LDHTVILWDYTDGVLLK----------------TENIIASAALENDKTIKLWR SDVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------ ----------------------------------------------------AHVFKEMC YNYRDSLSAGIIVAGWDRKNGGQVYSVPLGGMIVHQPFAIGGSGSTYVYGHVDATFKEK- ------------------------------------------------------------ --------------------GKKGLKGAVDLKSVQLLGNAYKEKVQPDLDELEVNMEDNE DAESTKSEVKLGKLQFSLDYDFQKGELSVGVIQAADLPGMDMSGTSDPYVKTYLMPDKKK KFETKVHRKTLNPVFNETFTFKVPYAEIASKTLVFAIYDFDRFSKHDQIGQVKVPLNSID LGRVVEEWRDLTSPENENEKENKLGDICFSLRYVPTAGKLT------------------- ------------------------------------------------------------ ----GGMQLGINSKGDRLRHWYETLSKKDQYFQKWHTLQ------MVLADLGRKITTALR SLSGATIINEEVLNAMLKDICAALLEADVNIKLVKK------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXX----------------------------------------- ------------------------------------------------------------ --------------------------------------DTDRDGKISFEEFCTVVGTMDV HKKMVVDVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------- ----------------PRKMRTAFSQHTHKLRPSITPGTVLILLAGRHKGKRVVFLKQLG SGLLLVTGPYHLNGCPLRRINQNYVIATKTNVDISKVDLPERLNDSYFRRLKLKKPKHLE GEIFETKKEAYTVSDERKEDQVAVDTQILEAVRSHADKKLLFGYLGATFSLKNHQFPHKM IFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---CDYCLLTSACNRN-GIPEDLLI CKDCNAKAHPSCMDYSTDLAKRARTSPWQCIDCKTCFVCEDSGESDSMLFCDACD----- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------EKALF AVPRNYKLVAVTAGELYDNAQGYGPIISSLPQALSRFNFIYN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------KDYDPFQEHRPQ---------------------RIADREDEYRA RRRQMIISPERYDPFAEGGKTPDPASMRTFAAVMREQHLTKEQAALQMQMREKAKAG--- ------------------------------------------------------------ -------DLHSVNGNSEAPAAKATKKRRWDQTADDTPSSKKKSSWDEVPTTPSHKGGETP SAITAGASTRMWDATPGHATPGATTPGRD---------NTVYIGAQDAMIPAYPRIQNDE KNQYLRHELDYLLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------------------- ----------------------------------SQRDNIFRNVEVLIYVFDVESRELEK DMHYYQSCLEAILQNSPDAKVFCLVHKMDLVQEDQREMIFRKKE---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------FPAG LYFCFKKLTDANIFIIMYGVTSIYFAGVMVRLMLVLAPVMCILSGIAVSSTLTTYMKNLD AHKKADANYPIKKE---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQETFNLFDNRGDGRI FARHVGEFLRSIGLNPTEADVKRCKDPDVRISFEQSLPYITSLNKNRDTSTHEDFVEGFK VFDKEQNGFMSSAELRHLLTSLGERLTDEEVNELVQGMEDTHGNINYEDFVRMVLS---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------PRCGK LHPDGLAALARADEYEQVKAVAEYYAEYRALFEGAGTNPGEKTLEDKFFEHEVKLMVNAF MQQFHFGVFYSYVKLKEQECRNIIWISECVAQRHRAK------------AGRKISKIPFK VLDAPELQDDFYLNLVDWSSQNVLSVGLGTCVYLWSACTSQVTRLCDLSCDNDSVTSVSW SER--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------WKYPSLVQIAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTR STKESKSVLNMFTRIRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------- ---------------------------------HRTILLSEIQEHKISLSTDG------- ------AQAQIPVSKVMDERRNTLLGELENSQRESLQNLLASINYINLYGPQGLALTSDG HVVVAYSGNHCFKVYRYLMAAGPIAERNQDATVYTGGLDEKVSEAILWELFLQAGPVVNV HMPKDRVTQTHQGYGFVEFMGEEDADYAIKIMNMIKLYGKPIRVNKASAHQKNLDVGANI FIGNLDPEVDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFEASDAAIEAM NGQYLCNRPISISYAFKKE----------------------------------------- ------------------------------------------------------------ ------------------------------------------------------XRWPKY IRLQRQRAILMQRLKVPPSINQFTQTLDRQTASQLFRLMDKYRPESKQEKKQRLKARAEQ RAKGKEDAPTKRPPTVRSGVNTVTSLIEQKKAQLVVIAHDVDPLEIVLFMPALCRKMGVP YCIVLGRVVRRKTATCLALATTNPEDRSSLAKLTDAVKTNFNERGEELKRHWGGGVMGSK SQARVAKLEKAKAKELVMRMRYVAAYLLAVLGGNHSPKAADIKKILSSVGIDADDTCIKK VIGELQGKNLEDLIAEGQTKLASVPSGGAAPAAEEKKEE--------------------- ------------------------------------------------------------ ------------------------------------------------------------ --ADLAGNKTVVLPVPAFNVINGGSHAGNKLAMQEFMILPVGAKNFTEAMRMGTEVYHHL KAVIKKQYGQDAC----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GKRENIGDLIQETLEAFERHGGD DAFINIKYMVPTYESCMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXX--------------------------------RELLKPREYKVDLDS RLGRSQVITKTTPSAQQGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRIERSSLD QVKKRFEMNKKKKEEKKKEYDFEERMKELRE----------------------------- --------------MGCTMSQEERLAMERSKQIEKNLKGDGMQAAKDIKLLLLGAGESGK STIVKQMKIIHEGGFTSEDNKQYKPVVYSNTIQSLVAIIRAMGTLNIAFGEPERESDAKM VLDVIARMEDTEPFSEELLHAMKRLWSDTGVQECFGRSNEYQLNDSA------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------XXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX-------VLKDTAVAGTVNFVEEG-VTVTGSISGLVKGLHGFH VHQYGDNTNGCTSAGPHFNPEGKVHGAPGDDIRHVGDLGNVEAGHIKITDKLLKLTGPNS II---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------NIHDVTLHTDAIHRGGGQIIPTAR RCFYACELTAAPRMLEPVYLVEIACPEAAVGGIYGCLNKRRGHVNEESQVPGTPMFTVKA YLPVNESFGFTADLRSSTGGQAFPQCVFDHWQILIVAETRKRKGLSEGVPPLDKFLDKMX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------HRIKEDGIEKIYPVNAIA FHNIHNTFATGGSDGFVNIWDGFNKKRLCQFHRYPTSIASLAFSHDGSILAIASSYMYE- --------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -VQKVMEDGDLQKTELHEIILVGGSTRIPKVQQLVKEHFSGKEPNRGINADEAVAYGAAV QAGVLSGEEDTGDLVLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQIFSTAADNQP- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXX-------------------------------------------------------- ------------------------------------------------------------ --------------------------------------------------ELDVLKASKA KDLERLQELTKLYGEYEQVVVEDRIEKEKARRKAEQELEELKAAIKLQAWFRGVMVRKGL GPYSKKKKK-PKVGINGFGRIGRLVLRAACEKVQVVAVNDPFIDLDYMVYMFKYDSTHGR FNGTVALVVNGHAITVYNEMKPNNIKWGESGADIVVESTGVFTTLEKAKAHIEGGAKKVV ISAPSADAPMYVMGVNHTKYTADQNIVSNASCTTNCLAPLAKVINDNFGIVEGLMTTVHA YTATQKTVDGPSSKAWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPVPDV SVVDLTVRLQKGASYDEIKAAVKGPMKGFLAYTEDQVVSQDFRGDTSSSIFDARAGIALN DKFVKLITWYDNEYGYSFRVIDLITH-----QDDLATATLRRKDRPNRLVVEEAINEDNS VVSLSQAKMDELQLFRGDTVLLKGKRRRETVCIVLSDDTVTLRPGRINRCVRNNLRVRLG DIVSIQACPDVK------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------EMFAQTL QQSRGFGGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX------------------IESKHEVTILGGLNEFIVKFYGPSGR------------- ------------FMNRIFHPNIDEVSGTVCLDVINQAWTALYDLSNIFESFLPQLLTYPN PIDPLNGDAAAMYLHKPEEKRK-----------------------------------XXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX----------------TKSQKFCRNEYNLTGLCNRASCPLANSQYATVREEKGICYL YMKTIERAAFPARLWEKVKLSRNYEKALQQISDSLIYWPRFLKHKCKQRFTKITQYLIRI RKLTLKRQKKKV------------------------------------------------ ---------------------------------------LVQARFSVSPRIKKFSIYRWN PEKPGDKPHMQTYEIDLNTCGPMILDALIKIKNEIDPTLTFRRSCREGICGSCSMNINGG NTLACLCKIDENTSRTSKIYPLPHMYVVKDLVPDMNNFYAQYKYIEPYLKKKDEKEEDMG KKSYLQSPADRAKLDGMVDCILCACCSTSCPSYWWNGDKYLGPAVIMQAYRWIMDSRDDF KQERLSKLRDEWSLYRCHTIMNCTKTCPKGLSPGAAIGEMKKVMLGYASSGIPKQDIRPN HTIYINNLNEKIKKDELKKSLYAIFSQFGQILDIIAMKTLKMRGQAFVIFKDINSATNAL RSMQGFPFYDKPMRIAYSTKDSDAIAKMKGTFVERPKKKRENEEKQESKKK--------- ------------------------------------------------------------ ----------------------------------------GTNFPTHIFPSLVGRPTLRS NTKVGDVEIKDLMVGDEASQLRSMLEVNYPMENGIVRNWEDMIHLYDYTFGPQKLDVSPP DCKLLLTEPPMNPTKNREKMIEVMFEHYQFHGLYIAIQAVLTLYAQGLLTGVVVDSGDGV THICPVYDGFALPHLTGRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRIMKEKLCYV GYDVEKESR--------------------------------------------------- ------------------------------------------------------------ -------------------------------------------------XXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX--------------------------------------------- ------------------------------------------------------------ ---------------------PKDLGLPTEAYIAVEEVHDDGTPTTKTFEHVPSEIGAEE AEEVGVEHLLRDIKDTTVGTLSQRVTNQLMGLKGLLLQIQDIHSYLEKVCAGKLPINHQI IYQLQDIFNLMPNVNLQEFVKAVFVKTNDQMLVVYLASLIRSVIALHNLINNKVQNRDAE RNEGKDSSMGLLFTKIWSLFTNEEHKVIIVGLDNAGKTTILYQFLMNEVVHTSPTIGSNV EEVVWKNVHFLMWDIGGQESLRSAWNTYYTNTEFVILVIDSTDRE--------------- ------------------------------------------------------------ ------KGIPIRRVAFNDPSQLPSDYSTTPGGTIFSTTPGGTRIIYDRAFLMQLRNS--- ----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------IAEAKGLDVGRVNCPVIGGHSGVTIIPL ISQCTPPVSFPESEREALVVRIQEAGTEVVKAKAGAGSATLSMAYAGAKFAGSVVQALNG EQGIVECAFVKSDETEAKYFSTPILLSRNGMEKNLGLGKLMENEVKLLETAMPELQANIK KGED-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------GSGS NIDLCVITKKVEYLRPFDVANEKGVRQGSYRYKRGTTGVLTKNVKKIEYEILXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXMAFTFAAFCYIVALILSAFLIFFAIYHIIAFDELKTDYKNPIDQ CNSLNPLVLPEYGIHIFFNILFLFATQFGSLLFNAPLIAYHINRYMHRPVMSGPGLYDPT TIMNADQLSKAMREGWVKLAFYLISFFYYLYSMIYVLVS-XXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------RLFENLRMLPHAPGVQM QNIPEDALKNDTTNNERISIRASDKRIACDEEFSDSEDEG---------------XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXESAEEFDNRYEAFFNRQDVDGWDIRKAMNDL QGLDLVPEPRIVIAALKACRRVNDYALAVRYMEAVQNKCGDKVGEIWPYLRQEIKPTLDE LGILTPEEMGYDKPELAVEDVMDMVVRVRGLPWSCTQEQVTSFLEGCEIVGGVHGVHFTF VRDGRPSGEAYIELATDKDVEKAVTKNNEHMGKK-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------RCLVKKRALIAGGGAPEIELSIRLLEYSQTLSGMEQYCFRAFAEALEIIPFT LAENAGLNPIATVTELRN------------------------------------------ ------------------------------------------------------------ ------------------------HGADDLIKREYGDFMTAAEDGYNVSVLYDENIPPNH ADVIKKAGLLKRNCFASVFEKYFDFQANHKRAVINYRDDESMYVEAKKEK---------- ------------------------------------------------------------ -----------------------------------------------------------X XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKTTYGPLKDEDRIF TNLYGRHDHRLKGAMARGDWYKTKK----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------XXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XMSADLAWSIIRDNSCFLIKRSELSFERNNLKNRNSNRYNGLIHRKTVGVEPCVDGKGVV LVTKRKQNKPAEMYVRTEMKRGSRRTMRSISKVLRSSNYRKDLKMAALRRASALMKSQKP VVVRRARXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------K DVPFPPSHRLAMSEVFDSKGKPKPDVLKQHFVLEGRVTEDVALRIINEGAALLRQEKTMI DIEAPVTVCGDIHGQFYDLMKLFEVGGPPAT----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------RAWNPFRSKLAAAILGGVEKIHMKPGCKVLYLGA ASGTTVSHVSDIVGPEGLVYAVEFSHRSGRDLINVKKKRTNIIPIIEDARHPHKYRMLVG MVDTIFADVAQPDQARIVAINAHHFLKNEG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------N RVYLNADSLMMNVGALEYMGDLD-----------------------GYDEFCVRIDQAQF GRREIEIAEQEMPGLIALRKRAVGDKPLSGAKVIGCTHITAQTAVLVETLVALGASVRWS ACNIYSTQNEVAAALAEASVPVFAWKGESEDDFWWCIDKCI------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------PDPDA IKMFVGQIPRSMDENDLRKMFEEFGPIYQLNVLRDKITGQSKGCCFVTFFTRKSALQAQN DLHNIKTMPGMQHPIQMKPADSEKRN-EERKLFIGMVAKKCDENSIRMMFAPFG------ ------------------------------------------------------------ ---------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXMVNVMKGILVECDPAMKNFLLHLDEKSEFGRKFIIQDLDDT HLFISADIVEVLQKR--------------------------------------------- --------------------------------GTLSTIEFQREALENASTNTEVLKVMGS AAKALKAAHNDLDVDKVHDLMDEVAEQQEIASEIGEAISNPVGFDQGIDDDELMNELEEL EKRK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------TAGDEEWIKVEVQLKDLILADYGKKNNVNVASLTQSE IRDIILGMEISAPSAQRQQIAEIEKQKKEK------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------NCYSASRPNLMIGKDTKVICQGFTGKQGTFHSQQAI EYGTNMVGGTTPGKGGQTHLGLPVFNTVKKEK---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFTRFVELGRVAYIA FGPDEGKLCVITDVLDQNRALVDGPCSGVARKILNFKQLHLTTFTIIGPSARSGSVKKAW EKAEITKKWTESTWAKKIEDRKTKLTLTDFDRFKLMKAKQARNRLVNIEFGKIRKGAKXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- ------------------------PKSTLANWVTEFERWCPSIRAVSLMGDKDKRAEFIR ETMMPGEWDVCVTSYEMCIREKSVFKKFNWRYLIIDEAHRIKKEK--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------NLVSAD TVIFIDSDFNPQNDLQAAARAHRIGQTRPVKVIRLIGQSTVEEIVLSRAEAKLKLTHSVI EGGQFSSTKAKEQLQDILKYGVDDLLSNEDSSMVDVDFENILGTTVDGEWQPEKKPEDIA GSSMDTGAGETSE-SMYTFEGIDY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------S KELQRRCNTLITLIERENMELEEKEKAERKK----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------ARIYLAKDKNTGQSKG FAFINFHRREDAARAIAGVSGFGYDHLILNVEWAKPS----------------------- ------------------------------------QIWDTAGQERFRSVTRSYYRGAAG ALLVYDITSRETYNALTNWLTDARTLASPNIVIILVGNKKE------------------- ------------------------------------------------------------ ----------------------------------------------------------NL DKPANPSSHEVVAWIKRILRVEKTGHSGTLDPKVTGCLIVCIEKATRLVKSQQGAGKEYV CIFRLHSAVEEEKKIGQAIEGLTGALFQRPPLISAVKRQLRVRTIYESKLLEYDK----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ETNKKFGAGGNQQTEAAKNTAKLDRETEELHHDKVKGDV AKTIMKARNDKKWSQKDLATKVNEKPQVVNDYEAGRAIPNQQILGKLERCLGVKLRGKDL GQPL---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCYSTNKLTEVGMLE TPKLQGKYDTGQLFLHRVFGYRGIVLFPWLAKVYDRDIVAS------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXX------IRRRKTTTFMDAKESTTVIELKKMVQGITKKAPED MKLWKDNKTLGDYGFTSSTARAQAPATIGLVFKEFEALEVAPLSTPPELPDVMKPQESSS SHTQEHVYRYQAVLMRARFDEHINEDLVKAKKLLEAGEKELWEQAHPQPLKFCNSPGGNA YGRVPYTPDAILDTWHPLEKAAYPEYFARREKRK---------------XXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX------SQSITIPDGLEVSIKARNVTVKGPRGTLRRNFRHLGVDIRKVNKKTITVEK WFGIKRELAAVRTVCSHIENMFKGVIRGYRYKMRSVYAHFPINIAISEANTLVEIRNFLG EKFTRKVHMLSGVQCTPSQAQKDEFILEGNDIELVSRSAALIQQSTTVKNKDIRKFLDGI YVSEKGHIVDD------------------------------------------------- ------------------------------------------------------------ -----------------------------CLSRSREYQLNDSAEYYLNALDRLTKSDYVP TEQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFIVAMSE YDLTLAEDQEMNRMMESMKLFDSICNNKWFTDTSIILFLNKKDLFEDKIKKSPLTICFPE YTGSNTYEEAAAYIQ--------------------------------------------- --XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXX------------------------------------------------- ------------------------------------------------------------ ---------------------------HLGCVPIANAGDYGGYYCPCHGSHYDASGRIRK GPAPLNLEVPYYEFPEEDLLIVGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXEFFKEFLQQAKQEFQEKWDKPAQNTASLDDFDRIKTL GTGSFGRVMLVQHKATREYYAMKILDKQK------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -MLSDTFLIVFISICTALLGEGLTWLLVYRTEKYKKLTAEVEKQNKKLEKTKETAGDTND RSQKKE------------------------------------------------------ ----------------------------------------------------------XX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXX----------------------------------- ------------------------------------------------------------ --NIRNWIRNIEEHASSDVEKMILGNKCDMNDRRQVSKERGEQLAIEYGVKFMETSAKAS INVEEAFFTLARDIKAKMDRKLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------PAAFEFNERFLLCLHDHVYSCQFGTFIGNCEKDRVDLRLSERTYSLWGFI- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------NRFEGFEPLTPWIID LLAHYSIMNNPTRQPLPINVAFKRSLQLLAAGFFLPGSAGITDPCESGNTRVHTVMTLEQ QDQVCFTAQTLLRVLSHGGYKQILGLEGNASIATEMSVWEGVVVTPSDKAYEK------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------RNVEQFVVCNRSNTVVIMNMQGQIVR SFSSGKREGGDFVCAAVSPRGEWIYCVGEDMVLYCFSSNTGKLERTINVHEKDVIGIVHH PHQNMIATYSEDGLLKLWKPMAQTVQLAPRLVDKVVPKLQTFWHYAKVELRPPQEWPEIQ KGFTNLVQAKTQKWRNVTVQEATLVAVEVACWFFVGECIGKGALVGYQIPGAVDFEAHXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXX------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------GDRTVMGRIANLASGLEMGETPIAREIGHFIHIVTSVAVFLGVSFFIIAFIL GYYWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTI CSDKTGTLTQNRMTVAHMWFDN--------------------------ARIAMLCNRAEF KVNQEEVPVLKRECNGDASESALLKCVELSIGHVTEFRAKNKKACEIPFNSTNKY----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------SFRNLSKGKKAALS AAAGGVGVVAALAELELHPPQFPWTHNGHFSSLDHMSIRRGYEVYKQVCAACHSMNYLAY RNLIGVCMTEEEAKKEAEEVMVTDGPNDSGEMFQRPGKLSDRFPQPYANDEAARSANNGA LPPDLSYITLARHGGEDYVFSLLTGYVEPPAGVNIREGLYFNPYFPGGAIGMAQALYNEI IEYSDGTPATQSQLAKDVSVFLRWAAEPEHDDRKRMGLKALVLFLLAAAYYMKRHKWSVL KSRKIA------------------------------------------------------ ------------------------------------------------GNTGIGLALAAA VKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTSASFDSPESHIGVAHRLKNEI----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------XXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------GDKAHVRFRF IKNPEYLRTDMRMVFREGRTKAVGNIIKLCPHVSANTRAQRAAKKAAEXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXMATYVKPSTRYAPADWFTSNYTISTNAERQRSASHDVRQEARQLRNETDNKTKWDQ LDNNTRLCD--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------XXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- ---EKCGVCTKSVYAAERIEAGGKPFHKMCFKCSTCDSAL-------------------- ---------------------------------LRPGETIVNNYPEGHQAAAVIPVLDLA QRQHGWLPISVMNKVAEVLSMPRMRVYEVASFYTMFNREPVGKHFIQICTTTPCILGGVG SDIILKTIINKLGINPGEMTKDGKFSLLEVECLGACINAPMVQINDNYYEDLTVKDMEEI LDDLIAGRVPTAGPRSGQNGRFSCEPKGGLTSLTEPPKGPGFGVRPDLXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXX------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---ILENANVLARYASICQANGIVPIVEPEILPDGDHDLATCQQVTEKVLAAVYKALSDH HIYLEGTLLKPNMCTPGFACPKRNTAEEIALATVTALSRGVPPAVPGVTFLSGGQTELEA TANLNALN---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------DEPILTALHDIKVKFSMGFTLEFYFNSNEYFTNTVLTKQYVMRSEPDETD PFSFEGPEIIKCTGCSVDWKKGKNVTVKLIKK---------------------------- -------------------------------------------------------IILLK EGTDSSQGKPQLISNINACQAVVDAVCTTLGPRGMDKLIVDARGKATISNDGATIMKLLD IVHPAAKTLVDIAKSQDAEVGDGTTSVVMLAGEFLKQCKPFVEEGVHPQIIVRAFRKASY LVVEKIKEIAVQVKKDPEELRSLLTKCAATALSSKLVAHQKDFFAKMVVDAVMMLDELLP INMIGMKKVTGGALEDSQLISGVAFKKTFSYAGFEMQPKKYENPKIALLNVELELKSKKE NAEVRVDNVEEYQSIVDAEWSILYEK---------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------S IVKINALTAASEAACLILSVDETIKNPKSAHDGGPPGGGR-------------------- ---------------------------------GALRPVVRCPTFKYNTRVRAGRGFTLE ELKAAGIGKREAKTIGVSVDYRRRNKSVESLQQNVQRLKEYKSKLILFPKKLSAPKKGDS SAEELKLATQLRGDVMPVQQIQKREKARKITDDEKKYSAFTALRQARANARLWGIRAKRA KDAMPNIKVFSGSSHCDLAQKITDRLGIELGKVVLKKFSNQETCVEIGESVRGEDVYIVQ SGCGEINDMLMELLIMINACKIASACRVTAVIPCFPYARQDKKE---------------- ------------------------------------------------------------ -----------------------AGMVLVGDVKDKVAILVDDMADTCGTVCHAAEKLLEA EALKVYSICTHGIFSGPAISRLNNSMFERVVVTNTIPKE--------------------- -------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXMARGQQKIQSQQKNAEKAAKAKHDQKKAAQAALQFVCA VCKSQMPDPKTYKQHFENKHPKAPLPDALKD-XXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------IHEEWAQGKEEMLQSMDFKKCRLNELK ALKKKHEAFESDLAAHQDRVEQIAAIAQELNVLEYHDCPAVNARCQRICDQWDILGTLTQ KRRNALDEAEHILERIDQL----------------------------------------- ------------------------------------------------------------ -------------------------------GQWIERHLDAIASISMQKGTLEDQLRKLK GYEQEVVNYKPNIDELERYNQDVQEAMIFENRHTQYTMATLR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------KVDEMIICGGMAYTFNKVLDGMKIGNSLFDEDGAKI VQELMDKAKKNGVQVHLPVDFVT------------------------------------- ------------------------------------------------------------ --------------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXFIPLFDRVLVQRLAAETQTKSGIMIPEKAQSKVLEATVVAVXXXXX TAGGNLIAPSVKPGDVVLLPEYGGTKVTVEDTDYQLFRDGDILGKFEXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------WDVEIRDDVIEECTKHGGVLHIYVDKAS PQGNVYVKCPSISAAVASVQALHGRWFA-------------------------------- DEREDEVSPTPPQPKKEK------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------GPCSDILKRNIAQYNSY VSLSVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----ILLVAVGYKTKLSALLLVVWLSCLNVYFNAWWNVPDYKPMRDFLKYDFFQTLSVI GGLLLVVALGPGGVSMDEHKKE-------------------------------------- ------------------------------------------------------------ ----------------------------------------------------------VF LDSCRKVSKLYPKIEFESMIIDNCCMQLVSNPYQFDVMVMPNLYGNIVDNLASGLVGGAG VVPGESYSHEVAIFEPGARHPFAQAVGRDIANPTAFILCGANMLKHMNLEFHSKLVKSAV ERVIKNGR---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---NNDTEVPTASTTNCAVNRCRWHQSGHQIAVGDDMGKIHIYDVGEHIAVPKADEWTRF MHTLQDLKNQLADAEDEA------------------------------------------ ------------------------------------------------------------ --------IKINAEKSRFLVERLKIVVLPTLCIAKDGKTTDYIVGFDDMGGSDDFPTEML EWRLGVTEAISYSGDLMTPPVTG------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------DH-MVDYAQEIRKVCPEGIDIVLDS LCGEDTNKGISLLKPMGKYVLYGASSSVTGETKSFLSFAKSWWQVDKINPIKLYDENKTI SGFRLRHLTIMDQLFQLYSDGKIRPQIDSAWPFEDASEAMQKLHDRKNIGKLVLDPSLXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXX---------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------MLQPILYGYAFNMPAEPVLLDSSSIQVDRILLMDTFFQ ILIYHGEQVAQWRKAGYQDLPEYENFKQLLQAPKDDAQEILQVRFPMPRYIDTDHEGSQA RFLLCKVNPSQTHNNMYADGGAAVLTDDVSLQVFMDHLKKLAVSSSSXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXPPQPAVIHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYR KRVVLDGEEVQIDILDDYAAIRDNYFRSGEGFLCVFSITEQESFQATADFREQILRVKND ENIPFLLVGNKADLEERRQVTIDEAQTRAQQWKVPYVETSAKTRANVDKVFFDLMRDIRS RK-------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------- ---------------------------------------------------MRDFNHLVI QNVNKAQMKVRSRSDNVAGVTLPIFESYADGSDSYELTGLSRGGQQVDKLKKNYARAIEL LVELASLQTSFVTLDEVIKITNRRVNAIEHVIIPKIERTLAYIISELDEMEREEFFRLKK VQGKK------------------PIRVVVTGAAGQIAYSLLYSIAKGDVFGSDQPLSLLL LDIEPMVGVLEGVVMELQDCALPLLKEVIPTADPAVAFKDVDVAILVGAMPRREGMERKD LLAANVKIFKAQGRSLDQHAKKNVKVVVVGNPANTNAFICKKYAPSIKKENFTCLTRLDQ NRAQAQIAAKEAVQNVIIWGNHS------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------YGRAKHLIYRDVKPENFLIGRQSN KKQHIINIIDFGLAKEYIDPETHKHIPYREHKSLTGTARYMSINTHLGKKK--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------ ------------------------------IRKGEKGIVVLAGDTNPVDVICHMPLVCEE GSLPYCYTPSKEDLGAACGSRRPTCMVMIKKHEDYDDLYQECSTDVSALPLPI------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------YVREMRILAYAQL LESYRSLTLDYMANAFGVTVSFVDQELSRYIAAGRLHCKIDKVGGIVETNRPDSKNWQYQ E----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------VNSSAEEH PESIIWGMPVLRVWLSGHCVVMKRSLGVGYAAVDNPVFFKQNTSMLLGDAKK-------- --------------------------------------------------------FHGK EESECCQRQWCGNIRAFTFDLRNNEGETVIRFKRDLHCQGFMCPC--SLQELEVQCPPGQ VVGYINEVCLEPK----------------------------------------------- ------------------------------------------XXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXAKKVT--KEEDCEVCVKFLNRFIGTLAKIEEEFKETC KTVK-------------------------------------------------------- ----------------------------------------------------XXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXMPKVVSRSVVCTDTKDQEEYGGEKPLYVYYCLCGQMSLILDCPVE KLP--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------EGAAKASQELSTDADKAKAEIAVECYE ALQKAV-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------- ------------------------------------------------------------ ----GQRGVVINTASVAAFDGQVGQVAYSASKGGIVGMTLPLARDLASQGIRVCTIAPGL FDTPLLRQLPEK----------------------------------------------XX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXMTALTQEEIISNTKTVVQGLDTLKNEH----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------SERMAQGSELQSGSNRGA SQSMGGVRHVSDLKVGQMSADSQSVIGLQAGNRGASQSGMVYGGQRHAGDVPAGNLSQGS HAYINLQMGSNQGASQSGMVMGKQR----------------------------------- ------------------------------------------------------------ ---------------------------------------GTTDYANQSGMSYGGRRDI-- -----------------------------------------TLTEHAQRVTSIDWAPNSN RIVTCGADRNAYVWPTLVILRINRAATCVKWSPLENKFAVASGARLISVCYFEQENDWWV SKHIK------------------------------------------------------- -----------------------------DSSVSVIDATLKTKYLPFQVCLWVTENSLLV AGHDCCPIVFSMDDANLSFVERMDGTK--------------------------------- ----------------------KXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSRRYDSRTTIFSPEGRLYQVE YAMEAIGHAGSCLGILAEDGVVLAAERRNTNKLLDEVSYSEK------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---DLGHDLTTVQRLQRKHEGLERDLAALGEKVKELDDTANRLMMTHPDQAQNIYDHQKE INERWNTLTEKADQGKGKLLDSYDLQRFSSDHRDLTSWINSMMALVSSDELAKDVTGAEA LLERHQEHRMEIDARAGTFQAFEMFGQQLLQKDHYASDEVREKLKDLADAREQLEQAWIA RRAKLDQCLEFQLFQRDCEQAETWMAAREATLEDSVDGGDSVESLIKKHEDFDRAISAQE EKIQALQNFATQLVDKDHYDTPGVVERRNQVLERWQNLKEAMLENRSKLGEAQSLQQFSR DVDEMEIWISEKLHTALDESYRDPANIQNKHQKHQAFEAELHANSDRIQAVLKMGDK--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ASSHAQNVAIEKRYTDVITRWQKLLADSEARKQRLLRLQEQYRQVEDLYLTFAK KASAFNSWFENAEEDLTDPVRCNSVEEIKALREAHDQFKASLSAAQADFNQLAALDKQIK SFNVGPNPYTWFTMEALEETWKNLQKIIKERDGELAREQQRQEENDVLRKQFAQAANAFH GWLTETRSAMMEGSGTLESQLEATKQKAVEVRAQRSQLK--------------------- ------------------------------------------------------------ ------------------------------------------------------------ --KEVEQAFRALTSGEKPFITSQELYSNLKKEQADYCISRMKPYMDKTGREIPDAYDYVD FTRSLFVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------GAGACETAVSIFLENYAVT LSSREQLAVAEFARAMLSIPKQLAVNAGLDSTELVARLRSCHNSSQCKKE---------- ------------------------------------------------------------ ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------- ---------------EAMVNENVSLVISRQILADVCTQLPNQPDDVAKEVSHFTLEKIQP RVISFEEQVASIRQHLADIYERNSCWREAANALTGIPLETGQKQYSNDYKLKTYLKIARL YLENEDPVQAEAYINRASLLQADS------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------MKLTDSVVKSLKPAKVFRENNDRINSIDFSANGDTLISSSDDESIVIYD CQSGTPKRTLHSKK---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX >Magelona_johnstoni MTDRKAVIKNADMAEDMQQDSVDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSGLLSQIRAFQTSAVTRDIDQAAKYIGAGAATV GVAGSGAGIGSVFGNLVIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLILFAF- ----------EAPHHRIRITLTSRNVKSLEKVCADLIKKAKDKLLKVKGPVRMPTKILRI TTRKTPCGEGSKTWDRFQMRIHKRLIDLDSPSETVKQITSISIEPGVEVEVTIADXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XMPPQITKKRKFVADGVFKAELNELLTRELAEDGYSGVEVRVTPLRTEIIILATRTQNVL GDQGRRIRELTSLVQKRFNFSNQGVELYAEKVATRGLCAIAQCESLRYKLIGGLAVRRAC YGVLRFIMES---------------------------------PIQDYVETAVRHVLLRQ GVLGIKVKIMLPWDMTGKIGPKNPLPDHVSIVEPKDEVPVKTPYSESMDKQMSKRGRGGT SGGKFHIALALPVAAVMNCADNTGARNLYVIAVHGRGACLNRLPAAASGDMVMATVKKGK PELRKKVMPAVVIRQSKLYRRKNGVFLYFEDNAGVIVNVKGEMKGSAITGPVSKECAELW PRIASNASSIRKKVTRVVALGPQVPEGENVFGVAHIYASFNDTFVHITDLSGKETIVRVT GGMKVKADRDEASPYAAMLAAQDVAERCKVLGINALHIKLRATGGNKTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPTDSTRRKGGRRGRRLMGKPRGLHTARKMRNHRRDQKWCDKD YKKSHLGTRWKANPFGGASHAKGIVLEKIGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP KDGSLNVIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKGKKERPRSXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXMGLTISSLFTRLFGKKAMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERAPEAYDELSKMLQEDELRD AALLVFANKQDLPNAMTAAEITEKLKLNTLRNRKWYIQSACATQGEGLYEGLDWLSNELA N--MPLAKDLLHPTAAEERRKCKLKRLVQHPNSYFMDVKCPGCYKITTVFSHAQTVVVCS GCATILCQPTGGRARLTEGCSFRRK--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXX------IKLFGKWTSEDVQVNDMSLSDYIGVKDKYAKYLPHSAGRFAVKRFR KAQCPIVERLTNSLMMHGRNNGKKMLTMRIVKHAFEIVHLLTGENPLQVLVQAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREAAFRNIKTIAECLADELINAAK GSSNSYAIKKKDELERVAKSNRMAEQMTLAGTLKGHGGWVTAIATTPMFTDMLLSASRDK SVILWDLRRDACYGIPKKRLQGHGHFVSDVVISSDGQFALSGSWDHTLRLWDLTTGETTR RFVGHTKDVLSVAFSADNRQIVSGSRDKSIKLWNTLGVCKYTIEDCHSDWVSCVRFSPNT ANPVIVSSGWDKIVKVWNLANCKLKTNHIGHTGILNTVTVSPDGSLCASGGKDGKTMLWD LNEGKHLYTLDSGEPMNALVFSPNRYWLCAATGPTITVWDLEDKNTVDVLKPELMGSSAQ APQVTSLCWSSDGQTLFAGYTDNLIRVWKVTIS--MREYKLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVFSIT AQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKLARQFNCAFLETSAKQK INVNEIFYDLVRQINKKNPDT-------ASEHINLKVTGQDGNVVHFKIKKNTPLRKLMS AYCDRTGVKLGAMRFRFDGNPINETDTPSKLDMEDGDTIDVFQQQTGGMATLPMNPKPFL NGLTGKPVMVKLKWGMEYKGYLVSVDGYMNLQLANTEEYIDGALTGNLGEVLIRCNNVLY VRGVEEEDEEGEMKD------------------MDINTAIQQVLKDTLAADGLVRGLHEC AKCLDKRQAHICIMAANCNEPNYVKLVEALCAEHSIPLMKVDDNKKLGEWAGLCKLDSEG HARKVVGCSCVVIREYGVQNQALDVVKTYLKSSKMTAIRKKLVIVGDGACGKTCLLIVFS KDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSI DSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQDEQTKRELMKMKQEPVRPDEGRA MAEKINAYSYLECSAKTKEGVREVFETATRAALQTKKKKKG-MDDFQSGEETAFVVDEVS NIIKESIEGAIGGNAYQHNKVNQWTSNVVEQCLNQLTKLGKPFKYIVTC----------- -----------------------------------MFSADAKIVKPNGAKPTEFESSISQ ALLELELNSDLKGSLRELFITGAKEIDIAGKKATVIYVPVPQLRAFQKIQVRLIRELEKK FSGKHVVFIGQRRILPKQTRKTKKKNQQKRPRSRTLTAVHDAILEDLTFPAEIVGKRIRV KLDGT------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------------DC YTSATGQTATLGNFAKATYAAISHTYKYLTPDLWKDTVFQKSPYQEFTDHLTKMSGGLDA LSMTEDDVKKILASTAHLGSNNIDFQMEQYSFKRKLDGVYILNLAKMWEKMVLAARAIAA IENPADVCVISARPYGQRAILKFAHYTGATAIAGRFTPGTFTNQIQAAYREPRLLIVTDP RTDQQPIVEASYVNIPVIALCNTDSPLRYVDIAIPCNNKSQHSIGLMWWLLAREVLRLRG TISREVPWDIMVDLFFYRDPEEAEKEPEVADWANEAVVAAVPI-AEDWSAAPADDWASTA P------MKFNKMVTSSRRKMRKRHFNAPSHIRRKIMSSPLSKELRVKYNARSIPIRKDD EVMVVRGHHKGPHHGKVVQVYRKKFVIHIE------------------------------ ------------------------------------------SGGGGVGMWRFYTEDSPG IKVGPVPVLVMSLLFIASVFMLHIWGKYTRGKKEAKRKSTLKEVVTRELTINIHRRIHGI GFKHRAPRAIKEIKKFTEKAMGTEDVRIEPRLNKHIWSQGVRNVPYRIRVRLHRKRNEDE DSANKLFTLVTYVPCASFKNLQTQNVDAKGTNEFLVNGKYRLVRKIGSGSFGDIYLGINI SNGEEVAVKLESHKARHPQLLYESKLYKILQGGVGIPHIRWYGEKDYNVLVMDLLGPSLE DLFNFCSRRFTMKTVLMLADQMIGRIEYVHNKNFIHRDIKPDNFLMGIGRHCNKVFLIDF GLAKKYRDNRTRQHIAYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRGS LPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLR QLFRILFRTLNHQYDYTFDWTMLKQKAAGGMNPEKLSKRIGGKGSARRKKKVVHRTATTD DKKLQSSLKKLNVNSIPGIEEVNMIKDDGTVIHFNNPKVQASLSANTFAITGHGETKLIT EMLPGILNQLGAESLSNLEKLARA-DDIDDDDDEVPDLVENFDEASKSEMTRYSITPANP GKSVKARGSNLRVHFKNTRETAQAIKHMHLRRSVSYLENVMLKKEIVPFRRFTGGIGRAA QTKAFKCVQGRWPKKSAEFLLQLLKNAESNAELKGLDTDFLVIEHIQVNRAPKMRRRTYR AHGRINPYMSSPCHVEVILAEREQAIAKPTSKKVSKKKLKKQKMMMTE------------ ------------------------------------------------------------ -------KMSEKDSKEEILKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQEADRD GDGEINETEFLRIMKKTSLYMGISRDKWHKRRATGGRQEPIRKKRKFELGRPAANTKIGP KRIHSVRTRGGNKKYRALRLDLGNFAWPSEGVTRQGRIIDVVYNASNNELVRTKTLVKNC IITIDATPFRQWYEAHFRKALGRKKTDETTIT------VGSKKVQRKITARVAAATIDAR LEEQFATGRLLACIASKPGQ---------------------------MALVCPTDFQHIL RVMNTNIDGKIKINIALTAIKGVGRRFATLVCKKAGVDITRRAGELSDSEVDRILTIIQN PRQYKVPDWFLNRQKDIKDGKFSQVTSNGLDNKLREDLERLKKIKSHRGLRHYWGLRVRG QHTKTTGRRGRTVGVSKKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRVRTK TVKKAAKVIIEKYYTRLTLDFHTNKRICEEIAILPSKKLRNKVAGFVTHLMKRIQQGPVR GISIKLQEEERERRDNYVPDISALEEVDSDTKDMLRQLDFGNLPGLQVIQQIS--MKWEY KEEHPYEKRKAEGEKIRKKYPDRVPVIVEKAPKAHVGDLDKKKYLVPSDLTVGQFYFLIR KRIHLRPEEALFFFVNNVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYGXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------GLGSGISLFIATNICETIVWKAFSPATVN TGRGTEFEGAVIALFHLLATRQDKVRGLREAFYRQNLPNLTNLLATVLVFAIVIYFQGFR VDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYIISQMLAAKFSGNFFVNLLG SWADVGGGGPARSYPIGGLCYYLSPPETLSHVVEDPIHAVLYIVFMLGSCAFFSKTWIEV SGSSAKDVAKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIG SGTGILLAVTIIYQYFEIFVKEQSEMGGMSTLLFXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX MVNVPKTRKTYC--LKCKVHQNHKVTQYKAGKASLFAQGKRRYDRKQQGYGGQTKPVFHK KAKTTKKIVLRMECTNCKYRKQLAIKRCKHFELGGDKKRKGQMIQFMGRVIRSQRKGPGS VFKAHTKHRKGAAHLRVLDFAERHGYIKGVVRDIIHDPGRGAPLAKVHFKDPYKYRTRKE TMVAAEGMYTGQYIYCGKKALLTIGNVLPVGTMPEGTIVCSLEEKTRDRGRIARTSGNYA TIISHHHESKTTRVRLPSGTKKVIPSANRAMVGIVAGGGRIDKPMLKAGRAYHKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGKASTVRRDTSAGRKVGLIAARRTGRLRGAKKIAD KAKRTKKVGITGKYGTRYGASLRKTVKKMEITQHSKYTCGFCGKESMKRQAAGIWSCNKC TKKVAGGAYVYSTTAAVQVRSAVRRLREATEMGRRPARCYRYCKNKPYPKSRFCRGVPDS KIRIFDLGRRKANTDDFPACIHLVSDEYEQLSSEALEAARICANKYLTKMCGKDAFHLRM NPKPFHIVRINKMLSCAGADRLQTGMRGAFGKPQGTVARVKIGMKIISVRCRDANTANVI EALRRAKFKFPGRQKIHVSKKWGFSKWERTDYEEMRATKRLVPD---------------- ----RVTKVLGRTGSQGQCTQVRVEFISDTNRSIIRNVKGPVREGDILTLLESEREARRL RXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMIEDRAGAKDLDQWIEQLNECKQLTENQVK TLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDR GYYSVETVTLLVTLKVRFKERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHSNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRC GNQAAIMELDDALKYSFLQFDPAPRRGEPHVTRRTPDYFLMGAYKYMQEIYRKKQSDVLR YLLRVRCWQYRQLASTHRAPRPSRPEKARRMGYRAKQGFVIYRVRVRRGGRKRPVPKGAT YGKPTNQGVNQLKFQRSLQNTAEERAGRKIGALRVLNSYWVGEDSTYKFFEVIMVDPFHK AIRHNAQMQWICRPVMKHRELRGLTSAGKKSRGLGKGHLFNQTIGGSRRAAWKKKNSLSL RRKRGIAIGRLSEERKAWRKDHPFGFVARPTKNPDGTLNLMNWECAIPGKKPTAWEGGLY KLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSLLDEEKDWRPAVTIKQILLGIQE LLNEPNIKDPAQAEAYTIYCQNKIEYERRVREQAMRFKDPSLGKSSKMLQHINFRMRCTL QDSRTFVGTFKAFDKHMNLILGDCDEFRKIKPK-ARTKEE-------------------- -----------------------------------GLQGPVRGVGGPSQQMMAPQPGY-- -GPPNDMTTFKLVLVGDGGVGKTTFVKRHLTGEFEKKYVATLGVEVRALIFHTNRGAVRF NVWDTAGQEKFGGLRDGYYIQGQCAIIMFDVTARVTYKNVPNWHRDLVRVCENIPIVLCG NKVDIKDRKVKAKAIIFHRKKNLQYYDISAKSNYNFEKPFLWLVRKLVGDPNLEFVAMPA LAPPEVEMDPTLMKEYEKDLIIAQQTALPDEDDDL-DGLRQYYITKIEGLQLTVTEGTQN LLRLQAQRNELNAKVRMLREELQLLQEQGSYVGEVVKPMDKKKVLVKVHPEGKFVVDIDK NIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEI KEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ KFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRLESGSGGDSEVQRTMLELLNQLD GFEPKQNIKVIMATNRIDILDSALLRPGRIDRKIEFPAPNEEARLDILKIHSRRMNLTRG INLRKIAEMMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFELAVAKVMQKDSEKNMSI KKLWKLGFAENFALSGAAAVISKTAAAPIERIKLLVQNQDEMIKQGRLKEPYKGVVDCTM RTYRTEGVLPFWRGNLANCIRYFPTQALNFAFKDKIKALFKSSPNEGQAMKFSKNIMSGG AAGAMSLCFVYSLDYARTRLANDAKVAGKRQFNGLVDVYRKTLKSDGVAGLYRGFVISCV GIVVYRGCYFGFYDTLKPILLGEDASLILSFALGYGVTISAGLVSYPIDTIRRRMMMTSG QAVKYSGSIDCAVKVIKGEGFMSLMKGAGANILRGVAGAGVLAGFDKFKEVYMKWR-MAD TSDLDRQIEQLRRCEVIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLK ELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQV YGFYDECLRKYGSITVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSINTLDQIRAIDRK QEVPHDGPMCDLLWSDPEETQGWGVSPRGAGYLFGSDVVAQFNATNDIDLICRAHQLVME GYKWHFVETVLTVWSAPNYCYRCGNVAAILELDEHLQRDFTIFEAAPQESRGKPQADYFL VRLPPEVNRILYVRNLPYKITGEEMYDIFGKYGAIRQIRVGNTPETKGTAFVVYEDIFDA KNACDHLSGFNVCNRYLVVLYYQSNKAFKKIDTEKKKQDLDSMKAKYGLSTPEKK----- ----------------------------------------------------LENVFIRG SKIRFLILPDMLKNAPMFKKVGAGRGKSAILRAAARGRGRA--------MQNDAGEVIDL YIPRKCSASNRIIGAKDHATIQINFAQVDE-NGIMNGNSTTYAICGQIRRMGESDDSLGR L---------MPRGPKKHLKRLNAPKHWMLDKLGGVFAPKPSAGPHKTRECLPLVILLRN RLKYALNYNECVSILKQKLIKIDCKVRTDKTYPCGFMDVITIDRTNEHFRMIYDVKGRFT AHRITPEEAKYKLCKVTKVYKTLNAVPLLVTHDGRTIRYPDPLIKVNDVIQYMGTKDDEY DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTA GQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADNNIVIMLVGNKSDL RHLRAVPTDEAKAFAAKNSLLFIETSALDSTNVEAAFQNILTEIYRIVSQKQIRESPGED NTKPIVLPPTDTGVGDRKRPCCMSSRYDRAITVFSPDGHLFQVEYAQEAARKGSTAVGVR GKDCVVLGVEKRAVQKLQEERTVRKIALLDDHVAMAFAGLTADARILINRARIECQSHKL TVEDPVTLEYITRYIAQLKQRYTQSNGRRPFGLSSLVMGFDGTPHLYHTDPSGTYNEWKA NAIGRSYKPVKEFLEKNYSPETITDKDTIKLTLKALLEVVQSGGKNVELAVMRKGQPLEM LEYTAIQEFITEIEAEKAAEEEKKK--GGGPGGGKKDDKEKKRKYEPPVPTSVGKKKKKV KGPEAANKLPLVTPHTRCRLKLLKLERIKDYLLLEEEFIRNQERLKPQEEKQEEERSKVD DLRGTPMSVGNLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDQLEPGCSVLLNHKVHAVV GVLGDDTDPMVTVMKLDKAPQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIRPPK GVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPS IVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSRGDVKVVMATNRIETLDPA LIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMT--------------------------- ----------------------------------------KRKPYSPFQGPTKVDYAVAR LDDLMNWARKSSLWPLTFGLACCAVEMMHFAAPRYDMDRFGVVFRASPRQADVIIVAGTL TNKMAPAFRKVYDQMPEPRWVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPT AEALLYGILQLQKKIKRMKFVQSWYRKDDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYA NNSNYKNDTMIRKEAYVHKSVMGELKRVIDDSEVMKEDDSLWPPADRVGRQELEIVIGDE HISFTTSKIGSLVDVNQSRDPEGLRTFYYLVQDLKCLVFSLIGLHFKIKPI--------- ----------LVMKSGKYVLGCKQTMRTIREGKAKLIIIASNAPSLRKSEIEYYAMLGKA GVHHFAGTNIELGNACGKLYRVTALSITDQGDSDIIRT----MTEYKLVVVGAGGVGKSA LTIQLIQNHFVEEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGF LCVFAVNNTKSFEDINQYREQIKRVKDADEVPMVLVGNKVDL------------------ ----------------------------MGDRYNIHSQLEHLQSKYIGTGHADTNKWEWL TNQHRDSYASYMGHSDMLNYFSLVENEAKARVRFNLMEKMLQPCGPPPERPED------- -----------------------------------KRNPRKIDWTVLYRRKHKKGNAETV VKKKGKRTSKRQRAYVGASMTDIIAKRSL--EFRKTQRDNAIKAAKKTQAEKPAAKPRVG GKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--KASKL RLLSKDELMHEFASYQKELSSLRVAKVTGGAAAKLARIRVVRKSIARVLTVYNQTQKANL RRLHKPLDLRYRKTRAIRRSLTKHEKNIKSAKELKKIRRNPLRKYAVKAKAKGPKVTDKV FFDVTIGGEPAGRIVIGLFGKTVPKTVKNFKTLAEGTQTYKGSGFHRVIKDFMIQGGDFT RGDGTGGKSIYFDDENFKLKHYGSGWLSMANAGKDTNGSQFFLTTKKTDWLDGRHVVFGK VIEGMSVVRKIESTKTDRDKPAQAVVIADSGSILVETPFAVTKEASEEKKKKAALKFMID CALPVEDQIMEVAAFKQFLQERIKVDGKLNNLKHAVVVTSDIPFSKRYLKYLSKKFLKRN NLRDWLRVVSSEHNKYELRYFQINEDEEEEE---SKEEKGEDEKVYGGCEGPDAMYVKLV SSDGHEFIVKRDHALTSGTIKAMLSGPGQFAENETNEINFREIPSHVLQKVCMYFTYKVR YTNSSTEIPEFPIAPEIALELLMAANFLDCDRVITLEEMKEHKTGKSIWMSIHDKVYDVT KFLEEHPGGEEVLLEQAGTFGTEAFEDVGHSTDARELMEQFQIGVLAEADK--------- --------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------EGPRMVR DVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTVNVKVI MATNRADTLDPALLRPGRLDRKIEFPMPDRRQKRLIFSTITANMNLSEEVDLEDYVARPD KITGADINAICQEAGMQAVRENRYVVLSKDFEKGYKNNIKKDETEHEFYK--VPLTKDMV ESRVILVLKLYDKVDAEKLTVDSHFMNDLGLDSLDQVEVIMAMEDEFGFEIPDAEAERLM KPADIVQYICDKEDV--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------NKGFKEQIYDVYRYLPPATQVCLISATLPHEILEMTSKFMTDPI RILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKM REANFTVSAMHGDMMQKERDAIMKEFRSGASRVLITTDVWARGLDVQQVSLVINYDLPNN RELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLIMALRRP FDPVAHELDANFRLTKFADLKGGCKVPQEVLLKLLEGL-QAQDPEQAHFQYVAAVPRIGI GMDSCVTPLRHGGLSLVQTTDFFYPLVDDPYMMGKIACANVLSDLYALGVTECDNMLSLL ASSNKMTDKERDVVVPLMLRGFKDLAEEAGTSVNGGQTVLNPWLTIGGVATTVCQPNEFI MPDNAVVGDVLVLTKPLGTQVAVNAYQWLDQPDRWNRIKLVVSEDDVRKAYQRAMFSMAR LNRTAARLMHKYNAHGATDITGFGLLGHANNLARIQKNEVGFVIHNLPVIAKMAAVSKAC GNMFGLLQGHSAETSGGLLMALPREQAAAFCKDIEKQEGYQAWIIGIVEKGTRTARIIDK PRVIEVPAKEKELLACIVGTVEGYFMNIDAHAEECFFDKVTSGTKMSLMFEVAEGGFLDI DVKIIGPDGKNIYTGERESNGKYTFAAHMDGTYQYCFSNKMSTMTPKIVMFSMDIGEKKK AQQNKLEEMINELSTSLTGVKHEQEYMAVRERIHRAINDNTNSRVVLWSFFEALVLVAMT LGQIYYLKRFFEVRRVV------------------------------------------- ----------------------------------QADEIEKLLCHKFMRFMMMRAESFFV LRRKPVEGYDISFLVTNTHTEQMYKHKLVDFIIHFMEEIDKEISEMKLAVNSRARLSAEE FLRRFSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVEDRLV TMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTMPNTFKTLDSWRDEFLIQASPRDPEN FPFVVIGNKIDLENRVVSTKRAQGWCHSKGEIPYFETSAKEAINVEQAFQTVAKNALAQE TEVELYNEFPDQIKLT----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPDHLGSDQRRVKDNDEEEKPIQALD EGDIALLKSYGVGMYHKMIKKTEDDLQSILKKVNELSGIKESDTGLAPPALWDLAADKQT LQSEQPLQVARCTKIINADTDDPKYIINVKQFAKFVVDLGDQVAPTDIEEGMRVGVDRNK YQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIDKLREVVETPLLHPERFVNLGI EPPKGVLLYGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMART KKACIIFFDEIDAVGGARFDDGAGGDNEVQRTMLE-----------------MATNRPDT LDPALCRPGRLDRKIEFGLPDLDGRAHIFKIHARSMSVEKDIRYELLARLCPNSTGAEIR SVCTEAGMFAIRARRKMATEKDFLEAVNKVIKAYAKFSATPRYMTYNMPTEKIHINIVVI GHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAESGKGSFKYAWVMDKLKAERERGITI DIALWKFETNKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGKGEFEAGISKGGQT REHALLAFTLGVKQMIVAVNKMDSTETPYDSARFEEIKKEVSNYVKKVGYDPKSIPFLPI SGWHGDNMLNMPWFKEYTVQTGTCLFEALDNIDAPSRPTDKPLRLPLQDVYKIGGIGTVP VGRVETGIIKPGMVVTFAPAMVSTEVKSVEMHHESMPEALPGDNVGFNVKNVSVKDIRRG NVTGDSAKDPPKEAGNFTAQVIILNHPGSINQGYAPVLDCHTAHIACKFSELKEKIDRRS GKKMEDTPKMLKNGDSGIVVMVPQKPMCVEAFSEYPPLGRFAVRDMRQTVAVGVIKSVEK KD-ASAKQTKAAQKAELEQLRQEAENLKCQIREARKAAADTTLAQAASSVENVGRIQMRT RRTLRGHLAKIYAMHWATDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAP SGSYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIVTSSGDMTCA LWDIETGQQTTSFTGHTGDVMSLSLSPDMKTFVSGACDASAKLWDIRDGMCKQTFSGHES DINAITFFPNGHAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSRSGRLLLG GYDDFNCNVWDTLKQERAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN------- ---------------LLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES FRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDA------NMVIMLIGNKSDLEARR DVKREEGEAFAREHGLIFMETSAKTAANVEEAFINTAKEIYQKIQDGVFDINNEANGIKI GPQHSPTN------------MTRGRTELGDVTVHNIKQLKRLNQVVFPVTYNDKFYKDVL EVGELAKLAYFNDIVVGAVCCREHKADNQRRLYIMTLGCLAPYRRLGIGTVMLKHVLKIC EADANYD-------------------------------------------------MPKQ ILEIKDFLLTARRADAKSVKIKKNTKFKVRCSRYLYTLVIPEKEKAEKLRQSLPPGLLVE DL-MSKINKETLNESIATVLEKKRKFTETVELQIALKNYDPQKDKRFQGSVRLPHVPRPK MSVCIIGDQAHLDEAKEFEVAHQSADDLKKLNKNKKLVKKLAKKYDAFLASDSLIRQIPR LLGPGLNKAGKFPSVLTHTDNMPAKISEVRSTIKFQMKKVLCLNVAVGNVEMTQEELRAN VALAINFLVSLLKKNWQNVRALYIKSTMGPVQRIYMADSDKLNIDSIIARLLEVRGSRPG KNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN IKLWKTFTD-----------------------PDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLNAGRPVTPPRSSAKNK GKMMFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEIVGTNVSTT YITCPADPKKTLGIKLPFLVM--------------------------------------- -----------WNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDEL PAEFKLYLPVQNK-----------------------------KTLTTVQGINPKYDLKKI VRACKKEFACNGTVVEHPEYGEVIQLQGDQRNNIS-----------------SAIFNFQS LLTVVLLLICTCAYIRSLAPRLLDKNKEGILGIFWKCARIGERKSPYVAVCCIAMAVSIL FWSSARLAASLARQLPRAATKKNALGAGFVASRHLSTTTEVSTILEERILGSSQVNLEET GRVLSIGDGIARVYGLKNIQAEEMVEFSSGLKGMALNLEPDNVGVVVFGNDKLIKEGDTV KRTGAIVDVPVGQELLGRVVDALGNPIDGKGNLGTKTRARVDVKAPGIIPRTSVNEPMQT GIKAVDSLVPIGRGQRELIIGDRQTGKTAVAIDAIINQKRFNESTDKKNHLMCIYVAIGQ KRSTVAQLVKRLTDADAMKYTIIVSATASDAAPLQYLAPYSGCAMGEYFRDNGTHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMDEPYGGGSLTALPVIE TQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQIKAMKQVAG SMKLELAQYREVAAFAQFGSDLDQATQNLLNRGVRLTELLKQGQYVPMAVEEQVAVIFAG VRGHLDKMDPANIVDFEAKFLKHLQSSQQEVLADIRSKGLITPESEAKLKDIVLKFLEGY MEALYSIPFSVLECPNLKLKKPSWVKQPSAMFMFAAVLCSYFLVTGGIIYDVIVEPPSIG STTDERGNTKPVAFMPYRVNGQYIMEGLASSFLFMLGGLGYVILDQTNSPVTPKLNRILL LCVAFICILVSFFVCRVFMRMKLPMPKVRKSRKPPPEGWELIEPTLDELDQKMREAETEP HEGKRKVEAMWPIFRIHHQRSRYLYDLFYRRKAISRELYEYCLKEGIADKNLIAKWKKQG YENLCCLRCIQVRDTNFATNCICRVPKGKLEEGKIVECVHCGCRGCSGEYAQVVKMLGNG RLEALCFDSTKRLCHIRGKLRKKVWINASDIILIGLRDYQDEKADVILKYTPEEARNLKA YGELPESAKINEDMDDQITFDEIDDILVRFLMKLSHETVTIELKNGTQVHGTISGVDVSM NTHLKTVKMTVKNKEPVQLDSLSIRGNNIRYFILPDSLPLDTLLIDDTPKARAKK----- ----------------------------SVKNNTQVLINCRNNKKLLGRVKAFDRHCNMV LENVKEMWTEVPKTGKGKKKSKPVNKDRFISKMFLRGDSVILVLRNPLXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX- ---EKGRQIYQQNCEECHTANESGRMKATGNTCQRLGEGTQQP-------ANMAKGFLQG EDG---FGSSPK--LPGTSLIFSGLKKRDE------------------------------ -------------------------------------FFPSLVAYMSSGPVVALALARDK AISYWRELVGPTNTLKARQTHPDSLRALYGTDDQRNGLHGSDSYSSAEREIRFFFPDSVV EPVPVGQAARDYLARAVNPAL---LTELCKQKPRDPVVWLADWLLEHNPNKPKVRMFEAR LQQGSLLKKVLEALKDLVTEAPWDCNSTGISLQAMDSSHVSLVSLLLRNDGFDTYRCDRN ISLGINMGNMSKMIKCAGNDDAITLKAGDNADTVTFMFESPNQEKVSDYELKLMDIDTEH LGIPETDYSCVVKMPSAEFQRICRDLSQIGDSVVICCTKEGVKFSASGDLGTGNIKLAQS ANVDKEEEAVTIEMQEAVTLTFALRYLNFFTKASPLSPQVTLSMCPDVPLVVEYKIADMG YIRFYLAPKIEDADE-KSLSAYHTSNKVAVGQVVAVIGAVVDIQFSGTLPPILNALEVEG RSPRLILEVAQHLGESTVRTIAMDSTGGIIRGTKVVDTGTSISIPVGPETLGRIINVIGD PIDERGPINATSHSSIHQEAPEFSEMSVEQEILETGIKVVDLLAPYAKGGKIGLFGGAGV GKTVLIMELINNVARAHGGYSVFAGVGERTREGNDLYHEMIEGGVISLKDASSKVALVYG QMNEPPGARARVALSGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDLGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIA ELGIYPAVDPLDSTSRILDPNVVGMRHYDIARNIQKILQDHKSLQDIIAILGMDELSEED KLTVTRARKIQKFLSQPFQVAEVFTGHAGKLVSLKETMDGFERILKGELDDLPEVAFYMV GPIEDVIAKADSLAQQQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXMGKQNSKLKPEVLEDLRQNTEFSDEEIQEWYKGFLKDCPSGNL SVEEFKKIYGNFFPYGDASKFAEHVFRTFDTNGDGTIDFREFICALSVTSRGKLEQKLRW AFSMYDLDGNGYISRQEMLEIVTAIYKMVGSVMKMPEDESTPEKRTDKIFRQMDKNLDGK LSLEEFIEG---------------MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNL TGLNEQVPHYRQALDMILDLEPDDELEDNPNQSDLIEQAAEMLYGLIHARYIMTNRGIAQ MIEKWQQGDFGYCPRVYCENQPMLPIGLSDVPGEAMVKLYCPKCQDVYTPKSSRHHHTDG AYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPLAYQLQWQASS----------- MTNTKGYRRGTRYMFSRDFRKKGVIHLSTYMTVYKKGDIVDIKGNGAVQKGMPHKCYHGR TGRIYNVTKAAVGVIVNKRVRNRIIPKRINVRVEHVKHSNCRKEFVDRVKNNDMLMKEAK AHVVCKRIPNQPRESHFVSTKFNKPEVVAPIPYEFIASVRTNFKQVSPADPSMEWKDITD RAAASSFWTELVKGFGITFAHMFKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAVCPAQAITIEAETRDDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEY STETREELLYNKEKLLNNGDKWEPEIAANLQADYLYR------------------DAETQ KALEEIDACQNDIDALNEKASEEILTVEQKYNKLRRPFFEKRSELIQKIPNFWETAFINH PQISAILDDEEDDLLHYLNQVDVEEFEDIKSGYRIKFFFKANPFFENDVLVKEFHL---- ------------------------------------------------------------ -----------------QKLTKEEELLLQDFSRNVTTKSSALFYGNALIVSAIPLWFFWR IHQMDPYILFGVMTLVSTYLVAFAYKNVKFLLKHK------------------------- ---------------DYEATTFSIFYNNALFLVLVIVASFYILRTFNPSVNYILSILSAS GLLALFSTSTK------------------------------------------------- ------------------------------------------------------------ ----------------RIVEHDEASAYAEENSLLFMETSAKTAMNVNDIFLAIAKKLPKS EQGVDLNQDQMAEYLASIFGTEKDKVNCSFYFKIGACRHSERCSRLHNKPTFSQTILLQN LYLNPQNTAQIQVTDVEMQQHYDDFFEEVFVELESKYGEIEEMNICDNLGDHLVGNIYCK FRYEEDAEKAVADLNNRWFNGRPVHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKP ISRELRRELYGRSNRSRSRSPQNRRSSPNNREGRRRRSRSRDRGNXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------KYWVNTLSSSSLLTNADYT TGQIFDLSDKLEQSEAQLGRGGFMEKKSEDKLSKATRDGCKTTIEAIHGLMSQVIKDKLF NQV-GLPRRIIKETQRLMAEPVTGISATPDDSNARYFHVVVAGPAESPYEGGKFNLELFL PEEYPMSAPKVRFVTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPD DPLANDVAEQWKVNEAQAIETARSWTRLYAENAEELLDYE-DEEHETKEVKGTYVSIHSS GFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILSMDVLCQAKSGMGKTAVFVLATLQ QLEPVDGQVSVLVLCHTRELAFQISKEYERFSKYMNSVKIAVFFGGMSVKKDEDVLKKNC PHIVVGTPGRILALAKVLNLKNIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMF SATLSKDIRPICKKFMQDPMEVYVDDDSKLTLHGLRQHYVKLKDNEKNRKLFELLDVLEF NQVIIFVKSVQRCMALAQLLVEQNFPAIAIHRMMTQEERLSRYQQFKDFQKRILVATNLF GRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKVPPSYGDLG KSARDLFGKGFNYGSFKLECKTKASNGVEFKTDGNSNHDSGKVSGGLETKYKCSEYGLTF LEKWNTDNILGTEITIEDQIAKGLKLSFDTSFAPQTGKKSGKIKTSYKREYVNLNCDVDF DFAGPTIHGASVLGYNGWLAGYQMSFDKSKLTRSNFAVGYATGDFTLHTSINDGSEFGGS IYQRVNSELETGVNLSWTAGSNATRFGLAAKYTPDKDSSFRAKVNNSSQIGLSYQQKVRD GVTLTLSSLLDAKNFNAGGHKVGVGLDLEADTARTTALDEYRKKLTEHKEVEARLKAMRE QLKQLTSDYDKSEDDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKTK LKSGTRVALDMTTLTIMRYLPREVDPLVYNMSSEDPGNINYTQIGGLGEQIRELREVIEL PLMNPELFQRVGITPPKGCLLYGPPGTGKTLLARAVASQLEANFLKVVSSAIVDKYIGES ARLIREMFGYARDHQPCIIFMDEIDAIRRFSEGTSADREIQRTLMELLNQMDGFDALGQV KMIMATNRPDTLDPALLRPGRLDRKIEIPLPNEQARLDILKIHAAPIAKHGEIDWEAIVK LSDDFNGADLRNVCTEAGMFAIRSERDYVIDEDFMKAVRKVSDNKKLESKLDYKPVMTDS VFSVISKFYSEYMENTPKKLKIIDSYLLYIMLTGIVQFVYCCLVGTFPFNSFLSGFISCV GSFVLGVCLRVQTNPQNKTDFLGISPERAFADFVFAHIILHLVVMNFIGSMTSPSQLLPL ELVDKCIGSRIHIIMKNDEEIVGTLLGFDD----XLEDVTEYQVTPEGRRVTKLDQILLN GNNITMLVPGGDGPE---------------------------APACGDVMKLQIKVDDDG KIVDAKFKTFGCGSAIASSSLATEWIKGKSLDEAGAIKNTDIAKELSLPPVKLHCSMLAE DAIRAALNDYKVKN-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXMGKFVKSGRVVVVLAGKYAGRKAVIVKSYDDGKGDKSFSHALVA GVDRYPRKVTKKMSNKKVKQRSKIKPFLKVLNFNHIMATRYSLFLVDKAVINKQAITDIG QKRRAKASVKTAFEKRYKEGKNKWFFQKLRFERTFIMVKPDGVQRGLVGEIIKRFEQKGF KLVAIKMQQASVDHLKEHYKDLSHLPFFPGLVTYMASGPVVPMVWEGDVVKTGRVMLGET KPQDSKPGTIRGDFAIQVGRNIIHGSDGVESAKNEIGLWFKPEELTAYTPCSEPWVYEXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMANKQRMRVANEKHSKNVGARGNVPKTLKQ AEEKYPVGPWLIALFIFVVCGSAVFQIIQSIRMXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMIRFI LIQNRAGKTRLAKWYMHFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIVYRRYAGL YFCICVDVSDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYSVVDEMFLAGEIRE TSQTKVLKQLLMLSSLEQPTIFGKILDGSIPADKIYEDDKCIAFRDVNPQAPIHFLVIPR KPIVGLSDDLALLGHLLGTARKVAVQANGYRVVINDGKDGAQSVFHLHIHVMGGRQMGWP P-------------------------GAGKTTILYRLQVGEVVTTIPTIGFNVETVTYKN LKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSMDRDRIGISK---------------- ------------------------------------------------------------ -GLYFHIAETEKKCFIEEIPDETMVVGRYKVEMFDRAQNQYIPTIAGLGMHVEVKDPEEK IVMSRTYAAEGRFTFTSHTAGEHVVCLHSNSTAWFGGGQLRVHLDIQVGEHANDYQQIAA KDKLTELQLRVRQLLDQVEQITKEQNYQRYREERFRQTSESTNQRVLWWSIAQTLILLVT GFWQMRHLKSFFEAKKLVMFYHVSLEHEILLHPRYFGANLLNTVKQKLFTEVEGTCTGKY GFVIAVTTIDNIGAGYIQPSRGFVVYPIKYKAIVFRPFKGEVLDAVVTQVNKVGLFVEIG PLSCFISRHSIP------------------------------------------------ ----------RLYVKAVFTGYKRGLRNQHENTALLKIEGVNNKTETEFYMGKRCAYVYKA RNKTACPGHKEASRLRVMWGKVTRSHGNSGAVRAKFRKNLPAKAMGRRIRIMLY------ ------------------------------------------------------------ -----------YYRGAMGIMLVYDITNAKTFDNISKWLRNIDEHANEDVEKFILGNKCDM DDKRQVTKARGDSIAREHGIPFLETSAKSNINVEKAFMDLAQAILNKMPQNEHIELHRKR HGRRLDYHEKKRKKESRQAHEMAHKAKKLRGLRAKLFNKKRHAEKIQMKKTIKMHEERKT KQKNNEEVPEGAVPAYLLDREGQSRAKVLSNMIKQKRKEKAGKWEVPLPKVRGMGENEVF KVVRTGKSRRKAWKRMVTKVTFVGEGFTRKPPKYERFIRPMGLRFKKAHVTHPELKATFC LPIIGVKKNPSSPMYTTLGVITKGTVIEVNISELGLVTQSGKVIWGKYAQVTNNPENDGC INAVLLVMAARPLISVYN--GADVTGTVQLPAVFRAPIRPDIVNSVHFQMLKNTRQPYAV SEKAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRR INVNQKRYAMCSAIAATGIPALVMSKGHRIEGTQEVPLVLDDKVESLKKTKEATQMLKKL KAWTDIEKVYKSKRFRAGKGKMRNRRRIQRRGPLVIYDQDNGITQAFRNIPGITLLNVSR LNLLKIAPGGHVGRFCIWTQAAFKKLDGLYGTWRKPASEKNGYNLPMSKMTNSDLSRLLK CDEVQSVLRKPKKDVRRKVLKKNPLKNVRVMLRLNPYAAVQKRAAINLLAKQ-------- ------------------------------------------------------------ -------------RDHLTEFSEHYASLGPPNPDNLPEDGKLKSEVMVKDTKRYYLDLKEN QRGRFLRVSPRSQLRSQIAIPAQGMIEFRDCLTDLLDEFGVDDHEGQGELPEARSMRVEN KMFYFDVGSNRRGVFMRISESNFRTAITIPERSWIRFRDIMA-------RRGRETQMRTQ INQRLVETGERERLKELLRTRLIECGWRDQLKAVCKDTVRQKGLEHITVDDLVAEITPKG RALVPDQVKKELVQRIRTFV-----MNIRCAKPDDLMNMQHCNLLCLPENYQMKYYFYHG LSWPQLSYVAEDEQGNIVGYVLAKMEEDPEDS-PHGHITSL------------------- ------------------------------------------------------------ ----MSHTILLVQPGSKPESRTYSDYETVNECLEGVCKIFEEYLKRMNPNSPSITYDISQ LFDFIDQLADLSCLVFQKSTGTYVPHNKDWLKEKVYTLLRKQAGKXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLSHRKFSAPRHGSLAFLPKKRSKRIRGKC KAFPKDDSSNQVHLTAFIGYKAGMTHIVRTVDRPGSKTNKKEVVEAVTIVEAPPMVVVGI VGYIETPSGLRAFKTVFAEHLSEQCRRRFY------------------------KEIDRD IAKMKKYCKVIRVIAHTQMTLLKQRQKKAHMMEIQLNGGTVSQKVDWAMEQLEKIVPIKN VFAQDEMIDVIGVTKGKGYKGVTSRWGTKKLPRKTHKGLRKVACIGAWHPSRVAYSVARG GQKGFHHRTEINKKIY-------------------------QKSINPMGGFPHYGMVNQD FLMLHGCVMGPKKRVLTLRKSLLVHTKRKALEKINLQLIDTTSKMGHGRFQTDAEKKTFL GVLKKDMQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLG LWDTAGQE---------------------------------------------------- ------------------------------------------------------------ ------------------------KKKKKKKTPFDIDAALDDISVDDNLPKKKKKKKKVF DLGDVEDALPQDTESLPKRKKKGNTDRDYTYDELLTRVFDIMREKNPDMVAGEKKRIVMK PPQVMKVGAKKTSFSNFTEICRMMHRQPKHLLAFLFAELGTSGSIDGNNQLIIKGRFQPK QIENVLRRYIKEYVTCHTCRSPDTILQKDTRIFFLQCETCGSRCSVASIKSGFQAVTGKR AAIRAKKT------------------------YDLVMTHALEWPSLTAQWLPDVTRPEGK DYSLHRLILGTHTSDEQNHLLIASVQLPNDNAQFDASHYDSEKGEFGGFGSVSGKIEIEI KINHEGEVNRARYMPQNPCVIATKTPSSDVLVFDYTKHPSKPDPSGECHPELRLKGHQKE GYGLSWNPNLNGNLLSASDDHTICLWDINTTPKEGRVVDALTIF---------------- ------------------------------------VNCLSFNPYSEFILATGSADKTVA LWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQSAEDA EDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEEPDTPAS ELEMPAPSRARVYADVNTHRPREYWDYESHAVEWGQQDDYQIVRKLGRGKYSEVFEAINI TNNEKCVIKILKPVKKKKIKREIKILENLRGGTNIIALLAIVKDPVSRTPALIFEHVNNT DFKQLYQTLTDFDIRYYLFELLKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA EFYHPGQEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPFFHGHDNY DQLVRIAKVLGTEELYEYIDKYQIELDCRFNDILGRHSRKRWERFVHSENQHLVSPEALD FLDKLLRYDHAERLTAREAMDHPYFYPIVKEAVPETLLKKRKAAAEAAKEKKATIFKRAE QYVKEYRIQERDQIRLTRMARKHDNFYVPAEPKLALVVRIRGINGLAPKPRKVLQLLRLR QINNAVFIKLNKATINMLRIAEPYIAWGYPNLKTVREIIYKRGYCNTEGRRLPLTDNALI EKKLGSDGIICMEDLIHEIFTVGPAFKKASNFLWPVKLNTPNGGWRKKNNHFNDGGDFGC REDKINNLLRKMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXEFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTI RLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERGTDVIIM LVGNKTDLSDKRQVSTDEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMEQTEQ TQ----------------------AVGLEKGHVTTTRAVKQSGTQSSGARKNQFIRDVTR EVMGFAPYERRAMELLRVSKDKRALKFCKKRLGSHIRGKRKREEMAAVLQKKRKAMVDAG TKKALAAIPLLKTKAGPRDGDLWVQRLKEEYQSLIKYVQNNKEADNDWFRLESNKEGTRW FGKCWYIHEMQKFEFDLEFDIPITYPTTAVELAIPELDGKTAKMYRGGKICLTDHFKPLW ARNVPKFGIAHAMALGLGPWLAVEIPDLIEKGVVRTK-------FLDDVRRMNKRQLYYQ FLNFGMIVSSALMIWKGLMVVTGSESPIV------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------KEY ADQLGIPFLETSAKNATNVEQAFMTMAAEIKNRMGPVTAAPNVKINASTPVKQSGGGCCE DSLGDEVLKMSTDEVSSRTRLMDNEIKIMRSELMRINHELQNQKDKIKENTEKIKVNKTL PYLVSNVIELLDMDPQDLEEEDGANIDLDAQRKGKCAVIKTSTRQTYFLPVIGLVDAEKL HPGDLVGVNKDSYLILETLPAEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELIEAVVLP MTHKERFETLGIQPPKGVLLYGPPGTGKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGA KLVRDAFALAKEKAPAIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFTSTSK IKVIAATNRVDILDPALLRSGRLDRKIEFPHPNEDARARIMQIHSRKMNVSSDVNFEELS RCTDDFNGAQCKAVCVEAGMIALRREATELTHEDYMDAIMEVQAKKKANLQYYA------ ------------------------------------------------------------ -------------------------DVTNEESFNAVQDWCTQIKTYSWDNAQVVLVGNKC DLEDERVVSTERGKQLADQLGLEFFETSAKENINVKAVFERLVDIICDKMSESLDSDPTS TKRLTENPNPQNTGCQCMRTHKMAVERDYISQPRLTYKTVSGVNGPLVILDDVKFPKYAE IVKLTLADGTERSGSVLEVSGSKAVVQVFEGTSGIDAKHTTCEFTGDILRMPVSEDMLGR VFNGSGKPIDKGPFVLAEDYLDIQGQPINPWSRIYPEEMIQTGISAIDGMNSIARGQKIP IFSAAGLPHNEIAAQICRQGGLVQRPGKGVIDDHDDNFAIVFAAMGVNMETARFFKQDFE ENGSMENVCLFLNLANDPTIERIITPRIALTTAEFLAYQCEKHVLVILTDMTSYAESLRE VSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLT GYITEGQVYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTREDHSDVSNQLYACYAIG KDVQAMKAVVGEEALTPEDLLYLEFLTKFEKNFISQGHYENRTIFETLDIGWQLLRIFPR ELLKRIPQSTLAKYYPRD-EGPGFIGIKFCQECNNMLYPKENKEERVLLYACRNCDYQQK ADNPCIYVNKITHEVDELTQIIADVIYDPTLPRTEDHPCPNCGHREAVFFQSQSTRLDEG MRLYYVCTATNCAHRWTEKPAYKVADIGLADWGRKAITLAENEMPGLMQMRRVYGPKKPL KGARIAGCLHMTLQTAVLIETLTELGADVTWSSCNIFSTHDHAAAAIAKTGVPVYAWKGE TDEEYLWCVEQTLVFPDGQPLNMILDDGGDLTNLVHEKYPQYLPGIKGLSEETTTGVHNL YKMAAAGKLKVPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDIMLAGKVCVVAGYGD- -------------------IDPINALQASMEGYEVTTMEEACKVGRVFVTTTGCKDILKG EHFSQMPEDAIVCNIGHFDCEIDVAWLNENCKEKTNIKPQVDRYTMKSGRHLILLAEGRL VNLGCAMGHPSFVMSNSFTNQVLAQIELWTKSDQYKVEVVTLPKKLDEEVAAAHLGHLGV KLTKLSEDQASYLGIPQEGPFKPEHYRY-----QPPTNAVEEPLDLVRLSLDERIYVKMR NERELRGRLHAYDQHLNMILGDVEETVTSVEIDEETYEEIYKSTKRTIPMLFVRGDGVIL VSPPMRTMSTSNVENLSPQIIRQVSKEIAELATDPPEGIKVFPNEEDITDIQATIEGPAG TPYAGGVFRMKLVLGKSFPSDPPKGFFLTKIFHPNVAKNGEICVNTLKKDWKPMLGIKHV LLVVKCLLIEPNPESALNAEAGKLLLEQYDDYSQRARLYTDIHAK-MFRSMFDAAKSSPF TSPFGLKINDSRSIAAPAEGDSCEFGSNKYYALCGFGGILSCGITHTAVVPLDLVKCRIQ VDPAKYGNIFNGFKVTVKEGGVRALGLGWAPTFFGYSMQGLCKFGFYEVFKVFYSGLIGE ENTYLWRTSLYLAASASAEFFADIALCPMEACKVRMQTMPGFAGTLRECFPKIYNGEGIS GFYKGITPLWGRQIPYTMMKFACFERTVEVLYKFVVPKPRAECTKGEQLVVTFVAGYIAG VFCAIVSHPADTIVSKLNQNPGGGVMGVAKELGMAGLWKGLGPRIIMIGTLTALQWFIYD SVKVFFRLPRPPPPEMPESLKKKLE--------------IIPLAFIYATEYLLFGLQLHL HQMYEEVITDYIHLSALALGGMLHFTYNDVGPVGALKLIWS--XXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLQPHLSKQ DLSTLNVNELHPLSYEIISRQATINIGTIGHVAHGKSTVVKAISGVQTVRFKNELERNIT IKLGYANAKIYKCDNNKCPRPGCYRSCGSSKEDDFPCDRQGCGRFRLLRHVSFVDCPGHD ILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQ AKEQYEQIIKFVQGTVAEGAPIIPISAQLKYNIEVVCEYVEKKIPIPIRDFTSQPKLIVI RSFDVNKPGCEVDDLKGGVAGGSILQGVLKVNMPIEVRPGIVSKNQSGHIKCKPIRSMIV SLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRLVGQVLGTAESLPDIYTELEISYYLLR RLLGVRTEGDKKGAKVQKLTKSEILMVNIGSLSSGGRVIAVKADLAKIGLTNPVCTEIGE KIALSRRVEKHWRLIGWGQIRRGLTVKP-------------------------------- ------------------------------------------------------------ --------------------------------------------RFKPMLQRGVELISLD ASWVSSASWYFLNVFGLRSMYNLILGQDNAADQTKVMQDQMSGAAMAMPPDSMKAFKAEW EALEICDHHWALEGVEDEI-MFLWDWFTGVLGFLGLYKKSGKLVFLGLDNAGKTTLLHML KDDRMAQHVPTLHPTSEELSMGGLRFTTFDLGGHQQARRVWKDYFPAVDGIVFLIDAFDK DRFAEGKAELDSLLADEQVADAPVLVLGNKIDKPGAASEDELRHIFNLHGQTTGRGNVPR SELRPMELFMCSVLKRQGYGEGFRWMAQYIN-VRRNQPGTKAESWCSWADESFEEMDSTL AVQQFIQQAIRKDFSNIDDILNPPDGQDEGVWKYEHLRQFCMELNGIAVKLQMECNP--- --------------------------------------------------IKESSVAKLG SVCRRVYRIFSHAYFHHRALFDEYENETALCRRFTTFVTKYNLMSKDNLIVPILEEQ--- ------------------------------------------------------------ ------------------------------------------------------TVANMI NGKTTEEIIKHFNIKNDLTPEEQEQLRLEN------XXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------- ------------------------------------------------------------ --SKKNSNVALVFSFLHKIVQVFCEYFKELEEESIRDNFVIIYELFDEVMDFGYPQTTDS KILQEFIMLEGQKLEVAPRPPMAVTNAVSWRSDGIKYRKNEVFLDVVESVNLLVSANGNV LRSEIVGAVKMRVYL--------------------------------------------- ------------------------------------------------------------ --------------KFKTTVGSCKYAPDQNSVVWTIKSFPGGKEYLMRAHFGLPSVISED PEQKPPIHVRFEIPYFTVSGIQVRYLKIIEKSGYQ------------------------- -----------------------------------------------------------G FVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDG KGRGKQVIAVARTCGLIFIVLDVLKPLQHKKLLEHELEGFGIRLNREPPNISYRRKEKGG INLTCPVPQSELDIDVVKSILGEYRIHNADICLRCDATAEDLIDVVEGNRVYIPCIYLLN KIDQISIEELDIIYKVPHCV---------------------------------------- -----------------------------------------------------------M AKHHPDLIFCRKQPGVAIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGSYQGRCVIC GGPGVSDAYYCKECTIMEKDRDGCPKIVNLGSAKTDLFYERKKYGFKKRPTFPAISGEKL MGKSDMRKVAVPANRYTPLKENWMKIFSPVVEHLHLQIRFNLKTRNVEIKTCKETEDIAA LQKAADFVRAFILGFEVEDALALVRLDDLFLESFKITDVKPLKGDHLARAIGRVAGKGGK TRYTIENVSKTRIVLADINVHILGSYNNIKVARTAICNLILGSPPSKVYGNMRAIASRSS ER---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -VEAEAAHGTVTRHYREHQKGNPTSTNPVASIYAWTRGLEHRGKLDGNQDLVDFCLQLEQ SCVDTIQAGEMTKDLAGCIHGLKNVKPEHYLNTMDFLAAISNRLNMGKLLSKIFGNKEMR ILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWR HYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDTIILIFANKQDLPEAMKPHEI QEKLGLTRIRDRNWYVQPSCATTGDGLYEGLTWLTSNAKS-------------------- ------------------------------------------------------------ -----DDSDEDLFGSEAERVKAERVKAYQAKKAPALIAKSNIILDVKPWDDETDMKALEE -XRTIKKDGLLWGASKLVALAYGIKKLQISCVVEDDKVSVDLLEE--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------YDLGQKMIESLT KEKCQAGDIITIDKATGKITKLGRSFTRARDYDAMGAQTRFVQCPEGELQKRKEVVHTVS LHEIDVINSRTQGFLALFSGDTGEIKTEVREQINAKVAEWREEGKAEIVPGVLFVDEVHM LDIECFSFLNRALESDMSPVLIMATNRGITRIRGTNYQSPHGIPIDLLDRLLIISTTPYE EKE--------------------------------------------------------- -------------------------------MAEFDLTTQMGQYLDRHLVFPLLEFLSVK GIYDEHEMLKGKLDLLSNTNMVDFAMDVHKNLYPDDEVPQSLKDKRAEVVSELRRVQADT EPIVKIFEDPEVMIQTSRDGRTLFETLAKDYDFKSSMLDTLYQFAKFQYECGNYSGAAEY LYFVRVLVPTNDKNALNALWGKLASEILMQDWETALDDLNRLKDVIDSSLQLLQQRTWLI HWSLFVFFNHPKGRDLIIDMFLYNPHYLNAIQTMCPHILRYLTTAVITNKTVLKDLVKVI QQESYTYKDPITEFLECLYVNFDFDGAQQKLRECETVLVNDFFLVACLGDFIENARLFIF ETFCRIHQCISISMLAEKLNMNPEDAEKWIVNLIRNARLDAKIDSKLGHVVMGTQAMSPY QQVIEKTKNLSFRSQMLCMNIDKKLGNKSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXMPKYYCDYCDTYLTHDSPSVRKTHCNGRKHKENVRLYYQKWLE EQVQKLVDDTTAAFKAGPGRNSSSKA---VVAAAAAA-QPPPNPQPPMGGPGPGRPGPP- -PSMGP------------------------------------------------------ --------------------------------------------------QGFGFSIMEG NQGSKEIYLKTITAGTPAAQDDQLAAGDQLLAIGNVSLLDMHYEKAIEELRKVQGTVTLT V------------------------LAALVGVAFCEANIHFREEFYESRWVASTKKGAEQ GVFKLSAGKFYGDAEKDKGIQTSQDAKFYGLSAKFEKPFSNEGKPLVIQFTVKHEQNIDC GGGYAKIFSSDLDQKDMHGDSPYLIMFGPDICGPGTKKVHVIFNYKGKNLLTKKDIRCKD DVFTHLYTLIVRPDNTYEVKIDNEKVESGELEADWDFLPAKKIPDPEAKKPDDWDEREKI DDPEDKKPEDWDKAEHIPDPDAKKPDDWDDEMDGEWEPPMIDNPEYKGEWKPKQIDNPAY KGKWVHPEIDNPEYTPDDKLYSYADIGAIGFDLWQVKSGTIFDNILITDDEETAKKVGDE TFGATKDPEKKMKDAQDEEERKQREEEEKKAKEEEDEKEEEKEEMDAPMPEPTLYTVKAM MILDNDGNRLIAKYYDDSFPTVKEQKNLFNKTHRANAEIIMFEGLTCVYRSNVDLFFYVV GSAQENELILVSVLNTFYDAISQMLRKNVEKRA--------------------------- -------------------------------------MNVFRLVGDLSHLLAIILLLLKI WKSRSCAGLSGKSQIMFALVFTSRYLDLFTNFISLYNTIMKVVFISAAYCTIYFLYAKFK ATYDSNHDTFRMEFLIVPVGGLAFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGE AETITSHYLFA---XRALYILNWLYRYYYEGFFDLIAIVAGCVQTILYCDFFYLYITKVL KGKKLSLPA--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------RQGRSDTYATEFDLEAEEYVPLPKGDVHKK KEVIQDVTLHDLDVANARPQGGQDIMSMMGQLMKPKKTEITDKLRKEINKVVNKYIDQGI AELVPGVLFIDEVHMLDIECFTYLHRALESTIAPIVIFATNRGKC--------------- ------------------------------------------------------------ ---------------------------------------------EFQVDEEGDQGLQKL KEKVRKRRGRGFATKSGVEEFEAMEVGGPGPQRSVEGWILFVTNVHEEAQEDDVFDRFAE HGEIKNLHLNLDRRTGFLKGYALVEYETFKEAQAAIDDLNGAELLEQKINVDWCFVQGPQ K--------------------LDELIQCGQITPQLALKVLLQFDTAINNALATRVKNRIN IKGHLNTYRFCDNVWTFVLNDVEFRQVDKVKIVACDGKS-FLFTSESVGEGHPDKICDQV SDAVLDAHLKQDPNAKVACETAAKTGMILLLGEISSNATVDYQKVVRDTIKGIGYDDSRK GFDYKTCNVLMALEEQSANIAEGVHVGRRDEDIGAGDQGLMFGYATDETEECMPLTVVLS HKLNAKIAELRRNGGMSWARPDSKTQVTVQYQFDNGACIPERIHTVVISCQHDENVSLEQ LRKELKEKVCDSVLPNNLVDENTVFHLNPAGSFYIGGPQGDAGLTGRKIIVDTYGGWGAH GGGAFSGKDFSKVDRSAAYAARWVAKSLVKAGLCRRCMVQIAYAIGVAEPLSICVFEYGT SHKTEKELLQIVKNNFDLRPGMIVKELDLKKPIYQKTAAYGHFGRPEFTWEQPKKL--MA GSALKRLMAEYKQLTLNPPEGIVAGPVNEENFFEWEALIIGPEGTC-------------- ------------------------------------------------------------ -------------------------------------------XXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- --LKRAIKTLNIVLEELDLHWVPVTKNWRLNERMYGGLQGLNKAETAAKHGEDQVKIWRR SYDIPPPTVEISDPRWPGHESKYQYLDRQLVPVSECLKDTIARTLPFWFDQIVPAIKKGE RVLIAAHGNSLRGLVKYLDNIPDDVIPGMNIPTGIPLVYELDADLKPVRHYYLADEAAVK AAMDKVAAQGKAKMEQETVSYNKQEYIETASGNKVSRQSVLCGSQNIVLNGKTIIMSDCI IRGDLANVRIGRHCVISSRSVIRPPFKKFSKGVAFFPLHIGDHVFIEEESIINAAQVGSY VHIGKNCVIGRRCVLKDCCAIADNTVLPPETVVPPFTVFSGSPG---------------- ----------DLMKHAAATLGSGNLRLAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTVT EFCTELSCPVMSAGPKYEYHWADGTTVKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKI GVPFPKNFLSIAKTILKRLFRVYAHIYHQHFKEVIQLSEEAHLNTS-------------- -------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------------------- ------------------------------------------------------------ -------------------------------------IETTVITDSAVFAVMSRVNKVII GTHTVMANGXXXXXGSHAIALAAKHHSVPLVVCAPMFKLSPQYLRSNDDGFNKFVSPQDI HNPVFDYVPPELVTLFISNIGGYSPSYVYRLLSELYHMIIPVRCFSCGKVIGNKWEAYLG LLQAEYTEGDALDALGLKRYCCRRMLLGHVDLIEKLLNYAPLEKRSPEPVEGRKHIDVQT ELYLEELSDRVEEADVECQTDAFLDRPPAPLFIPAKTGVD-------------------- ------------------------------------------------------------ --------------------RAFAQSYLADLVPSVFGSLSDNGYFYDPVERDVEQGFMPW LMERVEDELTKTVRGRVVVDGMVREVVRARAEAYRK------------------------ ------------------------------------------------------------ ------------------ASAVTQCYQDMGARHRARASTIQILKVDQIQAKDCRRANIKQ FHNSKIKFPLTHRVHKQLHKPRFTTSRPNTFFXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------- ----------------------QIHELFSRAGDIKRIIMGLDKVKKTPCGFCFVEYYLRE DAEACIRYVNGTRLDDRIVRTDWDAGFREGRQYGRGK----------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------EDNMVFIWNLQTKEIVQKLQGHTDVVLCCGCHPTENIIASAALENDKTIKLWR SDVMIIFKDAITGDELFSDTYQDSMYEVTAKD-VDIGGNPSSGLDVVLDDKKDFLTVFKA YVKSIVKLQFFQGSIPVEWAVPVMIFLKDGLIAEKVXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIAIAVVALLL LICCCVCICKKCCKRKKKDMGKKGLKGAVDLKSVQLLGNAYKEKVQPDLEELEVNMEDNE DAESTKSEVKLGKLQFSLDYDFQKGELSVGVIQAADLPGMDMSGTSDPYVKTYLLPDKKK KFETKVHRKTLNPVFNETFTFKVPYAEIASKTLVFAIYDFDRFSKHDQIGQVKVPLNSVD LGRVVEEWRDLTSPDNENEKENKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSD PYVKLSLMLNGKRIKKKKTTIKKCTLNPYYNESFSFEVPFEQIQKVTLII---------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------SPDNVVFVMDA SIGQACEAQSRAFKDKVDVASVIITKLDGHAKGGGALSAVTKSPVIFIGTGEHIDDFEPF KVQPFVSKLLGMGDIEGLIDKVNELKLDDEELMKKLKH---------------GQFTLRD MYEQFQNIMMSIMSYNGGAICAMKGKDCVAIAADKRFGIQAQTLSMDFQRIFEMGPKLFL GLPGLATDVQTVSQRLKFRLNLYELRENRSIKPKTFMSMVSNLLYERRFGPYFTEPVIAG LDPKTNEPFIANLDLIGCPMITEDFVVAGTCTEQLYGMCESLWEPDMEPDVLFESISQAL LNGVDRDAVSGWGAVVHIIEKDKVTTRTLKARMDXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPK EDKTTWKSNYFLKLVNLIDEYPKCFIVGADNVGSKQMQQIRMALRVLMGKNTMMRKAIRG HLENNPDLERLLPHIKGNIGFVFTKSDLNEVRDSIMNHKVEAPARAGAIAPCDVKIPAQN TGLGPEKTSFFQALSIPTKIAKGTIEITSEVHLIKLNDKVGASEATLLNMLKISPFNYGL VIQQVYDSGAIFAPEILDITNEDIIKKFMQGVTNVAALSLSIGYPTAASVPHSVVNGFKN LLAIAAATDITFKEAESMK-SSAKGRLLAVIGDEDTCTGFLLGGIGEINKHRHPNFLVVD KNTSIGEIEDAFKAFAVRDDIAIILINQNIAEMIRHVLDSHTEPIPAVLEIPSKDHPYDA SKDSILRRAKGMFSAE---GNEASLPLELCSTFDADEIKRLGKRFRKLDLDNSGSLSVEE FMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKESKLRFAFKIYDMD KDGYISNGELFQVLKMMVGSNLKDAQLQQIVDKTIIHADADGDGKISFEEFCHVVGTMDV HKKMVVDVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXLYEEVKLYRTSREREKYDNMADLFAVINTIQCLEK AYIKDSVTPKEYTAACSKLLVQYKAAFKQVQGDEFPSIESFMKKCKLDCPAALERIKEDR PITIKDDKGNTSKCIADIVSLFITIMDKLRLEIRAMDEIHPDLRDLMETMNRLSILPAEY DG---------------------------------------------MLSSLVKEHQARQ QSRKEDQERKKKEAIAATALTHALVDHLNSGVAQAYVNQKKLDTETKILQANAAHFAKQT MMWLKLVEDFNQSLKEIGDVENWARSIETDMRTISSALEYAYKARMVVKDIGGDKNGKTR TVRVNRMPKYYPTEDRPHKIKTAFHQHKRSIRASITPGTVLILVAGRHKGKRVVFLKQLS SGLLLVTGPFKINGVPLRRINQIYVIATKTKVDLGTL----------------------- ------------------------------------------------------------ ---------KKTPQEMLRQNQRALTKAIRELDRERSKMEQQEKKVIADIKKMAKAGQMDA VKIMAKDLVRTRRY--XFILMRANIQAVSLKIQTLKSNDAMAQAMKGVTKAMQRMNSQLK LPQ--------------------------------------------------------- -----------------------------------------------ENKTTASAEGLIS CSDCGRSGHPSCLQFTPNMIKSVKKYPWQCIECKSCGLCGTSDNDDQLLFCDDCDRGYHM YCLNPPLSEPPEGSWSCHLCIQE------------------------------------- ------------------------------------------------------------ ---------------------------------PYIPAHITKPKEHKRLFMVQLPEKALF AVPRNYKLVAAPLFELYDNAQGYGPIISSLPQALSRFNFIYN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------ATMISTMRPDIDNMDEYVRNTTARA FAVVASALGIPSLLPFLKAVCRSKKSWQARHTGIKIVQQIAILMGCAILPHLKNLVEIIE HGLVDEQQKVRTITALALAALAEAATPYGIESFDSVLKPLWKGIRQHRGKGLAAFLKAIG YLIPLMDAEYANYYTREVMLILVREFQSPDEEMKKIVLKVVKQCCATDGVEPQYIKDEIL PPFFKHFWNQRMALDRRNYRQLVDTTVEIANKVGAAEIISRVVDDLKDEAEQYRKMVMET IEKIMGNLGAADIDSRLEEQLIDGILYAFQEQTTEDVVMLNGFGTVVNALGKRVKPYLPQ ICGTILWRLNNKSAKVRQQAADLISRIAIVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLG SILGALKAIVNVIGMTKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADR------ ------------------------------------------------------------ -------------PFTVLPGLMNEYRVPELNVQNGVLKSLSFMFEYIGEMGKDYIYAVAP LLEDALMDRDLVHRQTSMAAIQHIALGVYGFGCEDALIHLINYVWPNIFETSPHVVQAFM GATEGIRVGLGPCKVLQYVLQGLFHPARKVRDVYWKVYNTVYIGAQDAMIPAYPRIQNDE KNQYLRHELDYLL----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------KLQKIL KQLHQSCQTDEGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPL IMGVIRECGGKMHLREGEYEKA--------------------TCLKYLVLANMLMKSGIN PFDSQEAKPYKNDPEILAMTNLVSSYQNNDINEFEKILKTNRKNIMEDPFIREHIEDLLR NIRTQVLIKLXKPYTRIHIPFISKE------EAENPLVTCILDNTILGRIDQVNQVLELD QGHARYSALDKWTGQLTSLHQAVVNKMAVLLMGKSGSGKTSMRSIIFANYIARDTRRLGA TIDVEHSHVRFLGNLVLNLWDCGGQEAFMENYFASQRDNIFRNVEVLIYVFDVESRELER DMHYYQSCLEAILQNSPDAKVFCLVHKMDLVQEDQRDLIFREREEDLKRLSKPLATSIWD ETLYQAWSSIVYLLIPNVEQLETNLTNFANIIDADEVLLFERATFLVISYCQRK------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------MVRLMLVLAPVMCILSGIAVSATLHNYMKNLD VKKKADANYPIKNEVATAVILMMTLFLMTYTFHCTWVTSEAYSSPSIVLSARAGDGGRII FDDFREAYYWLRHNTKEDAKVMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMAS TEDKAYEIMRELDVDYVLVIFGGLTGYSSDDINKFLWMVRIGGSTDRGEHIKE------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------LRKVNKSYPLLTTKVEESGEH VILGTGELYLDCVMHDLRKMYSEIEIKVADPVVSFCETVVETSSLKCFAETPNKKNKITM IAEPLEKGLAEDIENEVVQITWPRKRLGEFFQTKYDWDLLAARSIWAFGPDTTGP----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---REFMIKTRRRKGLSEDVSINKFFDDPMLLELAKQDVMLSYGM-ETFCLFDNRGDSKI QASQVGDVLRAMGQNPTEAEVRKCRDSDMRISFEQFLPILQTISKSKDHSTAEDFIEGFR VFDKDQNGYISAAELRHLLTNLGEKLNDEECEQLFQNQEDQQGNINYEEFVKMVMSG--- --FNIDNGYLEALTRGFKAGILKQSDYLNLVQCETLEDLKLHLQSTDYGNFLANEASPLS VSVIDDKLKEKMVVEFQHLRNQAVEPLSTFMDYITYSYMIDNIILLITGTLHQRSITELI PKCHPLGSFEQMEAIHIAATPAELYNAVLVDTPLAPYFIDCISEQDLDEMNIELIRNTLY KAYLEDFYKFCEDLGGATANVMCEALAFEADRRAFIITINSFGTELTKDDRAKLYPRCGK LHPDGLASLARADEYEQVKAVAEYYAEYRALFDGAGSNPGEKTLEDKFFEHEVKLMVNAF MQQFH------------------------------------------------------- ------------------------SVGLGTCVYLWSACTSQVTRLCDLSCDNDSVTSVSW SERGQLVAVGTHKGYVQIWDVTAGKKVSVLEGHSARVGALAWNADILSSGSRDRLILQRD IRTPSVVPERRLTGHRQEVCGLKWSPDHQHLASGGNDNKLFVWNMNNLNPVQTYTEHLAA VKAIAWSPH--------------------------------------------------- ------------------------------------------------------------ -----------------LVLVALYYILSGQGHRFDIGWFLESISPYLWANIGVALAISLS VVGAAWGILTTGASILGGGVKAPRIKTKNLISIIFCEAVAIYGIIMAIVITNQKNYYAGY CMFAAGLTVGFSNLFCGLSVGIVGSGAALADAQNASLFVKILVIEIFASAIGLFGVIVSI LQISKAKMGQKMAATRRLAKEFADDNDGANLLVWKGLILPDNPCFSKGAFKIEINFPAEY PFKPPKVTFKTKIYHPNIDEKGQVCLPIISAENWKPATKTDQVIKALVDLVDDPEPEHPL RSDIAEEYSRDRKKFNKNAMEFTKNNSEKRPAEXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGKLLGPKGLAVDNNGHIIVVDNKAS CVFIFQSNGKLLHKFGSRGDHQFAGPHFVAVNANNDIIISDFHNHCIKVFDEGGFLFSFG SNGEGNGQ---------------------------------------------------- -------------------AAGPIAERNQDATVYTGGLDEKVSEAILWELFLQAGPVVNV HMPKDRVTQTHQGYGFVEFMGEEDADYAIKIMNMIKLYGKPIRVNKASAHQKNLDVGANI FIGNLDPEVDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFIN-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------KKVTNPLFEKRPRNFGIGQNIQPKRDLGRFVRWPKY IRLQRQKAILLKRLKVPPSINQFTQACDKQLATKIFVLCDRLKPETKQAKKERLRAMAEA KAEGKTKDPEPKKDGIVYGIKEVVSLVESKRAALVVIAHDVDPIEIVLCLPALCRKMDVP YCIILGTAVNKKTVSCIAFSGTGAQNRDLLSGIVEAAKTNYNERAEEIRRHWGGGVMGSK SQAKVAKLESLKAREIASKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--ISKIHAR QIFDSRGNPTVEVDLTTEKGTFRAAVPSGASTGIYEALEMRDKVKGEYHGKGVKNAVNNV NTLIAPALVLDITNQEAVDQIMFDLDGTENKSKLGANAILGVSLAVCKAAAAQKGVPLYR HIADLAGNKTVYLPVPAFNVINGGSHAGNKLAMQEFMILPVGAKNFTEAMRMGTEVYHHL KAVIKQKYGQDACNVGDEGGFAPNILENNDALELIKTAIAKAGYTEQIKIGMDVAASEFC KQYDLDFKNPKSDQSKWLSSDALGEVYKGFTKSSPIVSIEDPFDQDDWEAWAKLTALQIV GDDLLVTNPKRVQDAIDKKSCNCLLLKVNQIGSVTESIQACKMSQKAGWGVMVSHRSGET EDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEQLGANALYAGVNFKNP----- ------------------------------------------------------------ --------------------------------------------------------LVQS AELAGVALVPYYRQILPILNLFKTRNLNSGDGIDYSQHKRENMGDLVDETLELFEQYGGE DAFINIKYMIPTYESC-MNAPPPFESFLLYDGEKKVQIEKDTKVPNAAMFTINKEDNTLG NLIRCQLLKDPQVLFAGHKNPHPLEHKMVVRIQTT------------------------- ------------------------------------------------------------ ---------------KLGHHYCIYCDAIMCDDINKMTHEKGYRHRQNI------------ ------------------------------------------------------------ --------------MGCTMSAEERAALERSKQIEKNLKEDGIQAAKDIKLLLLGAGESGK STIVKQMRIIHEGGFTQEDNKQFKPVVYSNTIQSLVAIIRAMGTLNIPFGDNERESDAKM VLDVIARMEDTEPFSEDLLAAMKRLWADHGVQECFGRSNEYQLNDSAKYFLDDLDRLGVK DYMPTEQDILRTRVKTTGIVEVHFSFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCV AMSEYDQVLHEDETTNRMQE---------------------------------------- ------------------------------------------------------------ --------LGNLAVLPLRTQHHGPAYDIIDESIYYFKANVFFKNYEIKGNADRTLIYITL YITECIKKLEKCQNKNQAQKEMHTLAIQKFSIPGDSGFPLNAMYAKPANAEEESSMRNFI MQLRRETGDRMIHKVMDPVTEKPSKWWMCFRKRKFMDKSLSRPG---------------- -----------------------------------------------WDTAGQERFRAVT RSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIFLIGNKSDLEAQRDVTYE EAKQFAEENGLMFLECSAKTGENVEDAFLDTAKKIYQNIQDGSLDLNAAESGVQHKPSTP RNPLNTDQVPSKEGCGCAPNSMM----APNIRGRIEFAQLITTAVAMNVTGLTHKKHGFH IHANGDLSNGCTSTGPHFNPDNLVHGGPEDIVRHAGDLGNIEPDLTRFMDSYIGLRGGYN IIGRAVVIHEKIDDLGRGGDEESSKTGNAGPRLACCIIG---MVNFTVDQIRAIMDKKDN IRNMSVIAHVDHGKSTLTDSLVSKAGIIAASKAGETRFTDTRKDEQERCITIKSTAISMY YELRDKDMGNGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQA IAERIKPVLFMNKMDRALLELQLEQEDLYQTFQRIVENVNVIICTWGSEDGPMGDIQISP SKGTVGFGAALHGWAFTLQQFAEMYSSKFKIEESKLMKRLWGDQFFSYKRGFTAYILQPI YNVFNVCMPKADALALCTKIGVKLVGDEKDLEGKPLLKCMMRKWLPAGDALLKMITIHLP SPVTAQRYRMEMLYEGPKDDEAAIGVKTCNPNGKVMMYISKMVPTADKGRFYAFGRVFSG TVKSGHKVRIMGPNYVPFKPIQRTILMMGRYTEPIDDVPCGNICGLVGVDQYLVKTGTIS DYEHAHNMKVMKFSVSPVVRVAVDCKNPSDLPKLVEGLKRLAKSDPMVQCIIEESGEKVV AGAGELHLEICLKDLEEDHACIPIKVSEPVVSYRETVEEESSTMCLSKSPNKHNRLFMKC CPMPDGLPEDIDSGAVAPRGDAKERGRYLADTYDYDVGEARKIWCFGPDSSGPNILTDVS KGVQYLNEIKDSVVAGFQWASKEGVMCEENMRAVRFNIHDVTLHTDAIHRGGGQIIPTAR RCLYACVLTAAPKLLEPVYRVEIQVPQDAVGGIYGCLNRRRGHVSEEQAVAGTTMLIVKA YLPVNESFGFTADLRSSTGGQAFPQCVFDHWQILIIGVTRKRKGLSEGIPALDKFLDKMX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- ------------------------------------------------------------ ----------------------------------------WDLRNMGYVQQRRESSLKYQ TRCIRSFPNKQGYVLSSIEGRVAVEYLDPSPEVQKKKYAFKCHRIKEDGIEKIYPVNAIA FHNIHNTFATGGSDGFVNIWDGFNKKRLCQFHRYPTSIASLAFSHDGSILAIAS------ --------------------MDFQNRAGGKTGSGGVASSSESNRDRRERLRQLALETIDI NKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQANLARRAAKEAKEAPAQPAPE KARVDIKKFVKIGRPGYKVTKQRDPESGQQSLLFQIDYPEIVEGVIPRHRFMSAYEQKVE PPDRKWQYLLFAAEPYETIAFKVPSREVDKDPKKLWTHWNRETKQFFLQFAFKHDPK-NN NPP---------MDDDQECWKLWRVRKTIMQLCHDRGYLVTQEELDQTLDQFKEQFGDKP SERRPGRSDLIVLVAHNDDPTDQMFIFFPEE----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------FIKLYKKKTGKDISK NNRAVQKLRREAEKAKRSLSSQHETRIEIESFFEGADFSETLTRAKFEELNLDLFRSTMK PVDNVLKDAGLEKKDVNEIILVGGSTRIPKVQDLVKAYFNGKKPNKGVNPDEAVAFGAAV QAGVLGGAQMQGDLVLVDVCPLTLGIAMEGDVFAPVIKRNSVIPTKKSQIFTTVEDNQDI VENAVYEGERSMCTDNHFLGKFDLTGIPPAPRGTPQIEVTFEIDANGILKVTAKELGTGQ IGSITINQNDNKLSKEDIERMVKDAEKFAEEDKLVRDRVNAKADLESTVYNVRTQLKDKE RLGGKLNKEDKEALTKAVEEQMKWLDDNPEASLEDLKKHKEDFENVLTPITTKLYKKRPP P---------ESALEDPELEAIKARVREMEEEAEKLKEMQNEVEKQMSAEEKMEADNRSV YVGNVDYGATAEELEAHFHGCGSVNRVTILCDKYSGHPKGFAYIEFADKDSVQTSLALDE SLFRGRQIKVSAKRTNRPGVSSTNRPPRGRSRRGR------------------------- ----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXPKIGINGFGRIGRLVLRAAIEKVEVVAVNDPFIELDYMVYMFKYDSTHGK FNGTVALVVNGKPITIYNEMKPNNIKWGAAGADIVVESTGVFTTLEKAKAHFDGGAKRVV ISAPSADAPMYVMGVNHTNFDPAQTIISNASCTTNCLAPLAKVINDNYGIVEGLMTTVHA YTATQKTVDGPSSKAWRDGRGAGQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPVPDV SVVDLTVRLQKGASMDAIKAAVKGPMKGFLGYTDEQVVSQDFRGDTHSSIFDARAGIALN DNFVKLITWYDNEYGYSHRVVDLITY-----QEDLQTAILRRKEKPNRLVVEEAINEDNS VVSLSQGKMDELQLFRGDTVLLKGKRRRETVCIVLSDDTVSDDKIRINRCVRSNLRVRLG DIVSIQACPDVKYGKRIHVLPVDDTVEGLTGNLFEVYLKPYFLEAYRPIRKGDIFLVRGG MRAVEFKVIETDPSPYCIVAPDTVIHCEGEPVKREEEEEALNEVGYDDIGGARKQLAQIK EMVELPLRHPQLFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSK LAGESESNLRKAFEEAEKNSPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQ RSHVIVMAATNRPNSIDTALRRFGRFDREVDIGIPDATGRLEILRIHTKNMKLSDDVDLE QIAQETHGHVGADLAALCSEAALQQIREKMDLIDLEDEQIDAEVLDSLAVTQDDFRWALS KSNPS-----------------------KKELQELVQYPVEHPEQFLKFGMTPSKGVLFY GPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFD ELDSIAKARGGNAGDGGGAADRVINQLLTEMDGMTSKKNVFIIGATNRPDIIDPAILRP- -----------------------LRKSPIAPDVDLEFLAKMTHGFSGADLTEICQRACKL AIRQSIEAEMQKEKQRSDNPDDYDPVPEISRDHFEEAMKFARRSVTDNDIRKYEMFAQTL QQSRGFGG---------------------------------------------------- ------------------------------------------------------------ -----------------------------DKTLKFWDTRTPQPMLTIQLPERCYAADVLY PMAVVGTANRGLIIYQLENQPQEFKRIESPLKYQHRTVRIFNDKKTNAPVGFALGSIEGR VAIHYVNPTNPKDNFTFKCHRSSVQDIYAVNGIAFHPAHGTLATTGSDGRFSFWDKDART KL-----------------QGQIFAYASSYDWSKGHEGFDAQKMKPHIFLRSCFDELKPS SKKMSSPSPGKRRMDTDVVKLIESKHEVTILGGLNEFIVKFYGPTGTPYEGGVWKVRVDL PEKYPFKSPSIGFMNRIFHPNIDEVSGTVCLDVINQAWTALYDLSNIFESFLPQLLTYPN PIDPLNGDAAAMYLHKPEEYKKKVSEYVKKYATEDALREQESSMSDFSEDEAQDMEL--- ------------------------------------------------------------ ---------------------------------------WLSELETFATKHDIIKMLVGN KIDMDVREVTREEGLKFARKHHMLFIEASAKTKEGVQCAFEELVEKIIQTPGLWETDGMT LSNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- ------------------------------------------------------------ ------------------------------------------------------------ -----------EETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENEVQSAAAKDALQ GFKITPTNAMKISFAKKMDAQGRRVVVCDNGTGFVKCGFAGSNFPEHIFPSLVGRPILRS SSKVGDIEIKDLMIGDEASQLRSMLEVTYPMENGIVRNWDDMKHLYDYTFGENKLNIDPT ECKILLTEPPMNPLKNRQRMVEVMFEKYGFAGVYCAIQAVLTLYAQGLLTGVVVDSGDGV THICPVYEGFALPHLTKRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMMKEKLCYV GYNVEQEQKLALETTVLVESYTLPDGRVIKVAGERFEAPEALFQPHLINVEGVGVAELLF NTIQSADMDIRSDFYKHIVLSGGSTMYPGLPSRLEREMKQLYLERVLKGDTDKLSKFKIR IEDPPRRKHMVFLGGAVLADIMKDKEEFWMSKADYQEQGMRVLEKL-------------- ------------------------------------------------------------ ---------EGVTSLKPGDHVVPLYIPQCKDCKFCRNPKTNLCSKIRSTQGAGVMPDGTS RFTCKGKSLFHFMGTSTFSEYTVCAEISVAKVDEKAPLDKVCLLGCGIATGYGAVLNTAK VEKGSTCAVWGLGAVGLAVLMGCKAAGASRVIGVDINTDKFEIAKQFGATECINPKDFEK PIQNVLVEMTDGGLDYTFECIGNVGTMRAALEACHKGWGESVIIGV-------------- -----WKGTAFGGWKSRDGVPKLVEDYMKGIVKVDEFITHNMALDKINEGFDLMHAGKSM DSYDVIANQPVVIDNGSGVVKAGFAGDQVPKYHFPNFIGRPKHIRVMAGALEGDMFLGPK AEEHRGLLSIRYPMEHGIVTDWNDMERIWQYIYSKDQLHTFAEEHPVLLTEAPLNPRRNR EKAAEIFFETFNVPALFISMQAVLSLYATGRTTGVVLDAGDGVSHAVPIYEGFAMPHSIM RVD--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------SKIEKVVVHPLVLLSVVDHFNRMGKVGNVKRVVGVLLGSNRQG VLDISNSFAVPFDEDDADKTVWFLDHDYLECMYGMFKKVNAREKIVGWYHTGPKLHQNDV LINELIRKYCPNSVLTIIDAHPKDLGLPTEAYIA-------------------------- ---VGVEHLLRDIKDTTVGTLSQRVTNQLMGLKGLLLQIQDIHSYLEKVCAGKLPVNHQI IYQLQDIFNLLPNVNLQEFVK--------------------------------------- --------MGLLFTKIWSLFTNEEHKVIIVGLDNAGKTTILYQFLMNEVVHTSPTIGSNV EEVVWKNVHFLMWDIGGQESIRSAWNTYYTNTEFVILVIDSTDRERLPITKEELYRMLAQ EDLKKA--------QDLKGAMSSAEISQQLNLTSVKDHGWHIQACCALTGEGLDKGLEWI GNQVRRKGIPIRRVALSDPSQLPSDYSTTPGGTIFSTTPGGTRIIYDRAFLMQLRNSPLT KSPPPNLPKIPGVTSP------------------------------------SFVEEYNN KVQIVSLDEETSEFTARSTFDHPYPTTKIMWMPDTKGVFPDLLATSGDYLRVWRVTRLEC LLNNNKNSDFCAPLTSFDWNEVDPNLLGTSSIDTTCTIWGLETGQVLGLVSGHVKTQLIA HDKEVYDIAFSRAGGGRDMFAS-------------------------------------- -------MAMDAMEVIILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHVCTAADDHQAL IWDIQQMPRAIEDPILAYTSSGEINQIQWSSTQPDWIAICYNNCLEILRVRQFSSTQKVA VLGASGGIGQPMSALLKENHLISHLSLYDIAHTPGVAADLSHINTRAKVTGHLGPDQLQE CLTGAEVVVIPAGVPRKPGMTRDDLFNTNASIVRDLADACSKYCPKAMLCIISNPVNSTV PIASEVFKKAGVYDPNRIFGVTTLDIVRANTFIAEAKGLEVDKVNVPVIGGHSGVTIIPL ISQASPAVSFPQEQRVALSVRIQNAGTEVVEAKAGAGSATLSMAFAGARFAGSMLKALGG EEGVVECAFVKSDETEVDYFSTPILLGKNGVEKNLGIGKLIEYEVSLVKEAIPELKKNIQ KGVDFINKN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -SEVSMIRDIREREIRIYTDAGRICRPLLIVENQKLLLKKRHIELLKEREYNNYSWQDLV ASGVVEYIDTMEEETIMLAMTPDDLQEKGVVYCSTFSHCEVHPSMILGVCASIIPFPDHN QSPRNTYQSAMGKQAMGVYITNFHVRMDTLANVLWYPQKPLVTTRSMEYLRFRELPAGIN SIVAIASYTGYNQEDSVIMNETAIQRGFFRSVFYRSYKDQESKKGLDQEEIFEKPSIDKV QGMRPAMYDKLD------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ICVEPPGGFSFENCKRNALLQKGF KIPKAVKTGTTICGVIYKDGVVLGADTRATEDTIVADKNCSKIHFISPNIYCCGAGTAAD TEMTTQLISSQLELHRLNTNREPMVCTANRMLKQMLFRYQGYISAALVLGGVDKNGPHLY SIYPHGSTDRLPYVTMGSGSLAAMAVFEDGYKKDMERADAIELVRKAICSGIFNDLGSGS NVDVCVITEKVEYIRPLEVANLKGVRQESYRYKKGTTAVLTTKVKKIAYDVVXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGLLTILKKMKQKEKEMRIL MLGLDNAGKTTILKKFNGEDIDTISPTLGFNIKTLEHRGYKLNVWDVGGQKSLRSYWRNY FESTDGLIWVVDSADRRRLQDCKKELDALLLEERLAGATLLVFANKQDLPGALSSDEIRQ AMDLDAIKTHHWMIQDCSAVTGEHLLLGIDWILDDIASRIFTLDHSKKKICYYYDGDIGN YYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKFHSDDYIKFLRTIRP DNMSEYNKQMQRFNVGEDCPVFDGMYEFCQLSTGGSVAGAVKLNKQAADIAVNWAGGLHH AKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY GEYFPGTGDLRDIGAGKGKYYAVNFPLRDGIDDESYESIFQPVMAKVMEMYQPSAIVLQC GADSLSGDRLGCFNLTLKGHGKCVEFIKRYNLPLLLLGGGGYTIRNVARCWTYETSIALG VDIANELPYNDYFEYYGPDFKLHISPSNMANQNTGEYLDKIKTRLFENLRMLPHAPGVQM QNIPEDTLKND--------------------------------------------PDGTF ECNICLDTAHDAVVSMCGHLFCWPCLHQWLETRPQRQVCPVCKAGISKEKVIPLYGRGST DQTDPREKLPPRPPGQRSEPENTGGFPGFGFGFQMSFGIGAFPFGFFASTFNFNDGRPQA PPNGTPQQVEEQFLSRVFLWVAVLFIFWLLIA---------------------------- ------------------------------------------------------------ ---------------------------LASGSHTGKINLFNVESGKKESSLDTRGKFTLS IAYSPDGKYIASGAIDGIINIFDMATGRLLEGHAMPIRGLCFSPDSQLLVTASDDSHIKI YDVQHANLAGTLSGHGSWVSNVAFCPDNTHFVSCSSDKTVKVWDAGTRQCIHTFYDHLDQ VWSAKYN----------------------ESDAEFDARYEAYFNRPNIDGWEIRKAMNDL QGEDLIPEPKIVDAAIRACRRINDFALAVRYLEAVKDKCGSRVNEVWPYMVQELSPTLDE LGIPTPEQLGYDKPELAVQDVYEL------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------NFQSQTGHTCHMRGLPFAAKEQDILDFFQPLNPVNVVIH YNSGRASGEADVDFATHEEAKEAVQKDRGMMQHRYIELFYQDKEKPAQIRESNITSAKAV ADAIRTSLGPRGMDKMIQSSNGDVTITNDGATILKQMQVLHPTAKMLVELSKAQDIEAGD GTTSVVVLAGSLLDASSKLLSRGIHPTTISECFQKAASKSVEIIDTMATPVDLKDRESLL KSASTSLNSKVVSQYSNILSPISVDAVLRVVDPARDDNVDLKDIKIVKKLGGTVDDTELI DGLVLPQHTTG-----------IGLIQFCISPPKTDMENNVVVSDYTQMDRVLREERQYI LNIVKKIKKAGCNVLLIQKSILRDALNDLAGHFLAKMKIMVVKDVEREDIDFVCKTLNLK PAASLDHFTPEILGSAELAEEVQVGSSKVVKITGITNPGRTVSLLVRGSNKLVLEEADRS IHDALCVIRCLVKKRALIAGGGAPE----------------------------------- -----------------------------------------------LLVSTSAITLAAE TVRSILKIDDIV---MILLEIKNRIIEETLTVKFENALAGGKPDTVDITIADFDGVLYHI SNLDGDKTKIRVSISLKFYQDLQKHGADELISREYGDHRTATEEGYSVSLLYDENL-VNH KELVTKAALLKRNCFASVFEKYFQFQESSERAVINYRDDETMYVEAKKDRVTVIFSTVFK DDDDVIIGKVFMQEFKDSRRNNQQAPQVLFSHREPPLELKNTDARTGDNIGYITFVLFPR HEKRENTIDLIHTLRDYLHYHIKCSKAYIHSRMRAKTSEFLKVLNRARPDVEKTEKRTIM LMFCPICANVLVVEEGPRCYRFACNTCPYIHNVTRKISNRKYPKLKEVDDVLGGAAAWEN VDSTQETCPKCEHDRAYFMQIQTRSADEPMTTFYKCCDAGCNHRWR-------------- ------------------------------------------------------------ ------------------------------------------------------------ -------QQAIHEAYKAGFLGKNACGSGYDFDVYMHRGAGAYICGEETSLIESLEGKAGK PRLKPPFPADIGVFGCPTTVANVETVAVSPVICRRGGDWFAGFGRERNQDVPMDFDGLVQ AQTALGTAALIVYNKQSDVVRGIARLMEFYKHESCGQCTPCREGTTWMVKIMNRFQKGDA QPAEIDMLWELSKQIEGHTICALGDGAAWPVQGLIRHYRPELERRMAEFAEKKFSQEQVE EMNQQLNQTRSQRVRAAMFPETLEEGIQIPSTQIHPDQPTAVQRLAEPSQMLKHAVVNLI NYQDDADLATRAIPELTKLLNDEDQVVVSQAAMMVHQLSKKEASRHAIMNSPQMIAALVN AMVNTTDVETTRCAAGTLHNLSHHRQGLLAIFKSGGIPALVKLLSSPVESVLFYAITTLH NLLLHQEGSKMAVRLAGGLQKMVVLLQRNNVKFLAITTDCLQILAYGNQESKLIILASGG PGELVRIMRSYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMNALAMHLGHQSQRLVQN CLWTLRNLSDAATRNQPMEGLLQMLTQMLSSNDINIVTCSAGILSNLTCNNTQNKIAVCQ VGGIEALVRTILQAGDREDITEPAVCALRHLTSRHPEAEMAQNAVRLHYGLPVLVKLLHP PSRWPLIKAVVGLIRNLALCPANHAPLREHGALPRIVQLLIRAHQDTQRNQSSYVDGVRM EEIVEGAVGALHILAREAHNRAVIRGLNCIPLFVQLLYSPVENIQRVAAGVLCELAADKE GAEIIEQEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLRR-- -MSSDLQWMIIRRTSSFLRKGNTFSTEPNNLLNRNSARYNGLINAKAIGIERAEDDKGIV LVTKNTTYKPAQSFNKVTLKKNSRKTLTSLRNTIRANRYRKDLKKAALRRASAILKSQKP RAIKDVKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------- -------------------------------NSEQKCLAMCMDRYMDTWNLVSRAYSQRL QKERSKL----------------------------------------------------- -GPSKNMVKQKAMRVLKQKRMYENQREQLGNQSFNMEQSNYAIQSLKDTKSTVDAMKVGV KEFKKEYKHIDIDKIEDLQ----------------------------------------- ---DTDSSFLDD-VAVPNAPTREPGAESVTNKDGVPVDEFGLPQIPQQXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------LKYQHLITNSFVECN RLMRWCPAPDCGNAAKAQYFDAKPVSCLCGHSFCFACGENWHDPVKCHWLKKWIKKCDDD SETSNWIAANTKECPKCHVTIEKDGGCNHMVCQSCKADFCWVCLGPWEPHGSSWYNCNRY DEDEAKKARDAQERSRHALARYLFYCNRYMNHMQSLKFEHKLYASIRLKMEEMQQHNMSW IEVQFLKKAVDILCLCRQTLMFTYVFAFFLMKNNQSIIFEDNQKDLENATEQLSEYLERD ITSDILVDIKQKVQDKFRYCESRRKVLLDHVHEGYEKEQWEYHEMANTDGKLSTTERVSK SVPFPPAHRLTMSEVFDPKGKPKPDVLKQHFILEGRVTEDVALRIINEGAALLRQEKTMI DIEAPVTVCGDIHGQFYDLMKLFEVGGPPATTRYLFLGDYVDRGYFSITERVYDACMEAF DCLPLAALMNQQFLCVHGGLSPEIHTLDDIRKLDRFKEPPAFGPMCDLLWSDPLEDFGNE KTTEHFTHNSVRGCSYFYSYAACCDFLQQNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSL ITIFSAPNYLDVYNNKAAILKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVT EMLVNVLNICSDDELMSEGDDTFEXAMAARKEVIRNKIRAIGKMARVFTVLREESESVLQ LKGLTPNGLLPMGALSGGKDTLTNAMSGFSPTHKISGFDEAKVLDKMNERMPPRKGFGGR GGGFGGGFGGRGG----GRGGGRGGRGGGRGGMRGGRTVVVEPHRHQGVFIARGKEDALV TLNLVPGDTVYGEKKISVEQGTKIEYRAWNPFRSKLAAAILGGVEKIHMKPGSKVLYLGA ASGTTVSHVSDIVGPEGLVYAVEFSHRSGRDLINVAKKRTNIIPIVEDARHPHKYRMLVG MVDTIFADVAQPDQARIVAINAHHFLKNEGHVVISIKANCIDSTAEAEAVFAEEVNKMRA EKIKPQEQLTLEPYERDHAVVVGQYRSAPKK----------------------------- -----YGLSQSVYTVEGGHRAIIFSRIGGVQNDIYTEGLHFRLPWFQYPIIYDIRSRPKR ISSPTGSKDLQMVNISLRVLS--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------SYTGSSSDEEEINPREKEQKSSKGFDDFCVRIDQAQF GRREIEIAEQEMPGLIALRKRAVGDKPLSGAKVIGCTHITAQTAVLVETLVALGASVRWS ACNIYSTQNEVAAALAEGGTSVFAWKGESEDDFWWCIDKCINSEGWQPNMILDDGGDATH WMLKKYPTMFKAVKGIVEESVTGVHRLYQLSKSGKLSVPAMNVNDSVTKTKFDNLYSCRE SILDALKRTTDMMFGGKQVLICGYGEVGKGCCAALKGLGAVVMVTEIDPICALQACMDGF RVVKLTEVVRQVDLIVTCTGNKNVVVREHLDRLKNACIVCNMGHSNTEIDVASLRTEELT WEKVRSQVDHIIWPDGKRIILLAEGRLVNLSCSSVPSFVVSITACTQALALIELYNAPNG RYKQDVYLLPKKMDEYVASLHLHSFDAHLTELSDDQAKYLGLNKAGPFKPNYYRY----- ----------------------EFGPIYQLNVLRDKITGQSKGCCFVTFFTRKSALEAQN ELHNIKTMPGMQHPIQMKPADSEKRN-EERKLFIGMVAKKCDENSIRMMFAPFGTIEECT VLREQNGQSKGCAFVTYANRQCAQNAIKAMHHSQTMEGCRSPVVVKFADTQKEKELKKLQ HMNNQVAMQ--------------------------------------------------- ------------------------------------------------------------ --------------------------------------------LFAGGMAGIFNWMVAI PPDVLKSRLQIKEEGIFALYKGATPILLRAFPANAACFFGYELFMKFID----------- ------------------------------------------------------------ -SEQRQRKMQKERLMNDFTSALNNFQVVQREAAAKERDSVEDVDLDLIKEREQAIRKLES DIMDVNQIFKDLGMLVHEQGEMIDSIEANVEVIHVEEGTTQLSKAREYQTKAR------- -------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXGGKKDKAPSPQEAIQRLRDIEEMLMKKSDFLEK KVDQELSTAKKRVALQALKRKKRYEKQLTQIDGTLSTIEFQREALENASTNTEVLKVMGS AAKALKSAHNDLDVDKVHDLMDEVAEQQEIASEIGEAISNPVGFGQDMDEDELMMELEEL EQEELDKQLIDVAQLPSVPTAEDDEMKELAAWAS-------------------------- ---TALIGLMTYFREAVVNTQELLDLLVKCENKIQTRIKIGLNSKMPSRFPPVVFYTPKE LGGLGMLSMGHVLIPQSDLRWSKQTDVGITHFRSGMSHDEDQLIPNLYRYIMPWESEFID SQRVWAEYALRTDMIQALGGVEGILEHTLFKGTYFPTWEGLFWEKASGFEESMKYKKLTN ASKDVMDNATTQKFWLDVQLRWGDYDSHDIERYARAKFLDYTTDNMSIYPSPTGLLVAID LAYNLHSAFGNWFPGAKPLIQQAMAKIMKANPALYVLRERIRKGLQLYSSEPTEPYLSSQ NYGELFSNQIIWFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPCT------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------EISAPSAQRQQIAEIEKQTKEQSQLTATTTRTVNKHGDEIITSTTSNYETTT FASKTEWRVRAISATNLHLRTNHIYVSSDDIKE--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TVYSDSRPNLMINKNTKVICQGITGKQGTFHCTQAI EYGTNMVGGVNAKKGGQSHLGLPVFSSVKEAMQETGAEASVIYVPPPAAAAAIIEAVEAE IGLIVAITEGIPQQDMVRVKRILLNQNKSRLIGPNCPGIIKPGEAKIGIMPGHIHMPGKI GIVSRSGTLTYEAVHQTTQVGLGQ-LCVGIGGDPFNGTNFVDCLEVFLKDPETKGIVMIG EIGGAAEERAAEYLMEHNGDNKKPVVSFIAGMTAPPGRRMGHAGAIISGGKGTATAKIEA LTAAGVQVTMSPAQMGTTIYK----------ESLKCTLCQERLEDTHFVQCPSVSDHKFC FPCSRESIKRQGAGSEVYCPSGKKCPLVGSNVPWAFMQGEIATILG-------------- -----------------------------------------TTFVVVSHSARTGTVRKAW AKAEIDQKWSQTTWAKKLANREKRAALSDYERFKVMKLKQTKSRLVSAMVSKSKKAA--- ---------------------------------------LKELTSLVKEVNADARRRGTF FDFAIVYPDTRSPSYRLREIGTTCSGHKGADDNVSLSNKRFQIGDYVDIAISPPR----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TDQHLVDNCGKMVLLDKLLTRVKAEDSRVLVFSQMTRML DILEDYCMWRGHDYCRLDGQTPHEERALSINEFNMPNSKKFLFMLSTRAGGLGINLATAD VVVLFDSDWNPQVDLQAMDRAHRIGQKKVVKVFRFITEMTVEERIIERAEMKLKLDNVVI QQGRLIDQNTNKEVLSMIRHGAEQVFASKDSTITDADIDAILESGEARTNELAKKLEGMG ENSLQNLTFDAPMESVYKFEGEDYRDKQKL-GIGHWIEPPKRERKANYAVDAYFREALRV SEPKAPKAPRPPKQPNVQDYQF-------------------------------------- ---------------------------FTNWSKRDFNQFIKANERFGRDDIESISRDVEG KTPEEVMEYSSVFWERCNELQDIERIMAQIERGEAKIQRRISIKKAMDAKMARYRAPFHQ LRIQYGTNKGKNYTEEEDRFLVCMLHKLGFDKENVYDELRTAVRQAPQFRFDWFIKSRTA MEMQRR------------------------------------------------------ --------------------------------------------------PGGAPAA--- --------------------------------------------------KATGKYVPPS LREGASRPGESMHSDETATIRVTNLSEDTRESDLQDLFRPFGTISRIYLAKDKNTGQSKG FAFINFHRREDAARAIAGVSGFGYDHLILNVEWAKPS----------------------- ------------------------------------------------------YRGAAG ALLVYDITSRETYNALTNWLTDARTLASPNIVIILVGNKKDLEAEREVTFLEASRFAQEN ELMFLETSALTGENVEETFLKCARSILTKIE----------------------------- ---QLQPSSKEKLDTSQWPLLLKNFDKLNIRTNHYTPIPAGCSPLKRSIEEYVKTGFINL DKPANPSSHEVVAWIKKILRVEKTGHSGTLDPKVTGCLIVCVERATRLVKSQQGAGKEYV CIFRLHSAVEEEKRIGQAIEGLTGALFQRPPLISAVKRQLRVRTIYESKLIEFDKERNLG ILWVSCEAGTYIRTLCVHLGLMLGVGGQMQELRRNRSGIQNEEDGLVTMHDVLDAQWQYD HNKDEEYLRRVVKPLEALLTKHKRIIMKDSAVNAICYGAKIMLPGVLRYDDGIEVNDEIV ICTTKGEAVALAIAQMTTAVMATCDHGMVAKLKRVIMERDTYPRKWGLGPKATIKKQMIK SGLLDKHGKANEKTPDNWSSSYVDYN---------------------------WDRKKTP RSGVLKTQKQLNAAQRQGAAVETNKKFNAGHNRQSEAAKNTAKLDRETEELHHEKVKMTV SQTIMQARNNKGWSQKELATKVNEKPQVVNDYEAGRAIPNQQVLGKLERCLGVKLRGKDI GQPLVLK---------------------------------------KDARVTAANDSNIW AAYEKTGRAVFNEDKLNFVLMDCEEGKVAITRVANLLLCIYAKESVGFGMLKAKAEALAE YLEEPLTQVAAS--ATARIQPKKQTLEDAYSPPANFLEIDVGSAQGKKRYTDYEVKMKTN LPVFRVKDSCVRRRYSEFEWLRNELERDSKIVVPPLPGKALKRQLPFRGDDGIFEDEFIE DRRKGLEQFVNKVAGHPLAQNEKCLHMFLQEPVIDKNYVPGKVRTTXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXMDVFLMIRRKKTTIFTDAKESTTVYQLKKIVEGITKVAPED MKLYKDVKTLGDSGFTSSTARAQSPATIGLAVKEFESLEVTPLSNPPELPDVMKPQESSS SHAQENLFRYQAVLMRARFDENKDEDLVKAKKLLEAGEKELWENQHPQPLKFCNSPGGNA YGRVPYSPDAILDTWHPLEKAAYPDYFARRERRKTEFIERWEKKYGNAE----------- ------------------------------------------------------------ -------VFEYLSMDLKKYLDSIPNGKFMDRMLAKSYCYQILQGILFCHQRRVLHRDLKP QNLLIDSKGVIKLADFGLARAFGIPVRVYTH----------------------------- ------------------------------------------------------------ ---------------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMKTLYVNQEVKVPEGVTVTVKSRTITVKGTRGKLVRNFRHLSVDIQMKNKSTVLVEK WCGGKKELAAVNTVCSHITNMIKGVTIGYLYKMKCVYAHFPINILIEDNNRAC-VRNFLG EKNNRMVKMQPGVSIRNS-QVKDEFILEGISIENVSRSAALLQQSTTVKNKDIRKFLDGI YVSYKGHI---MGCAVSGEDKAAQERSKAIDKTLRADGEKASREVKLLLLGAGESGKSTI VKQMKIIHEKGYSEDECLQYRPVVYSNTIQSMIAIIRAMGQLKVDFGHQDRSEDARQLFA LAGNAEDGEMSPELASVMKRLWKDSGVQECFSRSREYQLNDSAEYYLNALDRLTKPD--P TEQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFIVAMSE YDLTLAEDQEMNRMMESMKLFDSICNNKWFTDTS-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------QSMMDCLYAKCIPYITDCVMAELEKLGTKYRVALRIAKD ERFKRLPCLHKGTYADDCLVRRITEHKCYIVGTCDKDLKRRIRKVPGVPIMYLKQHQYSI ERMPDAFGAPK------------------------------------------------- --------------------GSERLIESLSLIDAVMPDVVESRKQSAQKNTNGEDHTNAM EIDDNLEIPSTKATVLRGHESEVFICAWNPTNDLLASGSGDSTARIWNMNDNSNANQLVL RHCIQKGGTEVPSNKDVTSLDWNSGGTSLATGSYDGFARIWSTDGRLISTLGQHKGPIFA LKWNKKGNYILSAGVDKTTIIWDASSGHCTQQFAFHSAPALDVDWQSNISFASCSTDQCI HVCKLGADKPIKTFQGHTNEVNAIKWDPQGQLLASCSDDMSLKIWSMKQDTCVHDLQAHS KEIYTIKWSPTGAGT--------------------------------------------- ------------------------------------------------------------ ---------------------------------VCSSCRPKLSCGPT-RGPLGNIRNLAM EKVASTVMFPCKYSNSGCNATLLHTDKTDHEETCEFRPYCCPCPGASCKWQGSLEQVMPH LMHQ-----------------------------------------------------FYA IVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHDGVQSAIMNSDCLVFDTNIAQLF ADNGNLGINVTISMCXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXPQQARYAHTDVQVPDFSFYRRKDAMSTRRAFTYMMVAGGGMAGAYAAKN LVHEFIGSMSASADVLALAKIEIKLSDIPEGKNATFKWRGKP------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------KMGYNIGVRLIEDFLARSNVGRCLDFRETADVIAKVGFKMFLNITPVVTNWS AAGDEFSLLLENNPLIDFVELPEGHSNL-------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------RFSEPHSRFYAAQIVLVLEYLHNLDIMYRDLKP ENLLIDSAGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVY EMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVN DIKNHKWFSTTDWIAIYQKKVEAPFIPKTRGPGDTSNFDDYEEEPLRISSTEKCAKEFAD FMLSDTFLIVFISVCTALLGEGLTWLLVYRTDKYKKLTAEVEKQNKKLEKTKETAGDSNE RSQKKKIERQEERLKTNTRDLSLVKMKSMFAIGFAFTALLSMFNSIFDGRVVAKLPFTPI SWLQGISHRNLIGEDYTDCSFIFLYILCTMSIRQNIQKLLGFAPSRA-----------CV QKFDNWSETDQVDFVEYLLARMCHYQHGQINTFLKPMLQRDFISALPAKNLDHVAETILS YLDAKSLCHAELVCKEWYRVISDGMLWKKLIERMVRFDPLWRGLAERRGWVQYLFRPKPG EPQKDHRFYRRLYPQIIQDIERIESNWRTGRHTLQRIHCRSETSKGVYCLQYDDQKIISG LRDNTIKIWDRNSLECVQVLTGHTGSVLCLQYDENIIISGSSDSTVRVWNVKTGEMMNTL IHHCEAVLHLRFNDGIMVTCSKDRSIAVWDMQSPTEINLRRVLVGHRAAVNVVDFDDKYI VSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRERLVVSGSSDNTIRLWDIECGACL RVLEGHEELVRCIRFDSKRIVSGAYDGKIKVWDLAAALDPRAPAGTLCLRTLVEH----- ------------------------------------------------------------ ---------------------------------------------AMGIMLVYDITNEKS FDNIRNWIRNIEEHASSDVEKMILGNKCDMHDRRNVSKERGEQLAIEHGVKFLETSAKAS INVEEGFFTLARDIKAKMDRKL-------------------------------------- ------------------------------------------------------------ -------------------------------YHPLAMQSKPLYDNKFGFIVMDGNGALFG TLSGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAEVAVQLFITNDKP NVAGLVLAGSADFKTELSQSDMFDPRLQAKILKIVDISYGGENGFNQAIELSSDSLANVK FIQEKKLISKYFDEISQDTGKFCFGVEDTLKALEMGSVEILIVWENLDIQRHVLKNHATD EEKIVFLKPEEEKDKTHFLDKETGVELELSESMPLLEWFANNYKNFGATLEIITDRSQEG AQFVRGFGGIGAILRYQVDFQSLEAFDDFGDDYNLDDY---------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------RFAHKQENHS---RRQVFEKLQQ FAFPVTNKLPFCFDFREDYEAN----------GWLVYDAVAEFKRQGLPTESWRI-SKTN EQYDL------QHVLFPVASLRRIELWTGYYCRWNPRMRPQEPIHLRNRELLVLKTQLQR KVEELQREVEAKSSPLRLFIPHVPFDLVQCESTFPRAKGAPDDKSLTDALLKRNGDLTPS ATEQSAVLNLVTKINSVMDNLIVAPGAFDAAQLEEVRQVGSHKKGTMIAGHNVADIVVIL KTLPTVEAVTALGNKVLEELKNSDPQELLTMLPNDAGFEISSSEATVKILITTIPPNLKK LDPDLHLDGKLMQGHLAAIRHARWFEENAFHSSIKVLIRLIRDLRNRFEGFEPLTPWIID LLAHYSIMNNPTRQPLPINVAFKRSLQLLAAGFFLPGSAGITDPCESGNTRVHTVMTLEQ QDQVCFTAQTLLRVLSHGGYKQILGLEGNASIATEMSVWEGVVVTPSDKAYEKPEK---- ------------------------------------------------------------ --------------------------------MKQTQPDRYVHLENMLARSYFDPREAYP EGQTKERRRAAIAHALSGEVNVVPPSRMLALLSQALKWQQHQGLLPPGSTIDVFRGKAAV REQ--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------DITVHSVHPLPRNVEQFVVCNRSNTVVIMNMQGQIVR SFSSGKRDGGDFVCASVSPRGEWIYCVGEDMVLYCFSSNTGKLER--------------- --------------------MAQVAQKGPVLIAFAQPRLSTFWRYAKVELTPPGDMPAVQ KGFQNLVQAKTGKYRNLTVKEATLVGVEIAMWFFIGEVIGKGTLVGYQIPGAVNFD--XX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXX--------------------------------------- -----------------------KILTRFKHENIIDIRDIIRARSIDDMKDVYIVQCLME TDMYKLLKTQQLSNDHVCYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFG LARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDVWSVGCILAEMLSNRPIFP GKHYLDQLNHILGVVGSPGHEDLCCIINDKARGYIQSLPFKPKVPWKQLADAKALDLLDR MLTFNPNKRITVEEALAHPYLEQYYDPADEPVTQEPFTFETELDDLPKERLKELIFNETN LLKER------------------------------------------------------- ----------------------------------FALVLRGGEKLNVHAEELVLGDLIEV KFGDRVPADIRVVSAHGFKVDNSSLTGESEPQTRTAEFTHENPLETRNLAFFSTNAVEGT CRGIVVNCGDRTVMGRIANLASGLEMGETPIAREIGHFIHIITSVAVFLGVSFFIIAFIL GYYWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTI CSDKTGTLTQNRMTVAHMWFDNRIVEADTSDDQSNATYDRNSPTWMSLARIAMLCNRAEF KVNQEEVPVLKRECNGDASESALLKCVELSIGHVTDFRKKNKKACEIPFNSTNKYQVSVH PDDPRYLMVMKGAPERILDRCSTILHQGKEEEMTEEWRDAFNNAYLELGGLGERVLGFCD YYLPADQFPLGYPFDADEENFPLTGLRFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVT GDHPITAKAIAKGVGIISEGNETVEDIAARLGIPVSEVNPRDAHACVVHGTDLRDMTPAQ IDDILRNHNEIVFARTSPQQKLIIVEGCQRQGQIVAVTGDGVNDSPALKKADIGVAMGIA GSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLLFILAD VPLPLGTITILCIDLGTDMVPAISLAYEQAESDIMKRQPRDPLNDKLVNQKLIGMAYGQI GMIQASGGFFSYFVIHAENGFWPIRLFGLRKEWDARGINDLEDSYGQEWTYAQRKVLEYT THTAFFVSIVVVQWADLMICKTRRNSIVHQGMKNHRLTFGLFFETSLAAFLCYCPGLDKG LRMYPLRFQWWIPPMPFSVAIFTYDEVRKYILRRNPGGWVEQETYYSFRKLTKGKKAALS AITGGAGVVAALAELELHPPHFPWSHNGNFSSLDHMSIRRGYEVYKQVCAACHSMNYIAY RNLIGVCMTEEEAKKEAEEVMVTDGPNDQGHMFQRPGKLSDRFPQPYDNDEAARAANNGA LPPDLSYITLARHGGEDYVFSLLTGYVDPPAGVNIREGLYFNPYFPGGAIGMAQALYNEI IEYSDGTPATQSQLAKDVSVFLRWAAEPEHDDRKRMGLKALILFLGAAAYYLKRHKWSTL KSRKI------------------------------------------------------- -------------------------------------------------------ALAAA VKAYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTSAAFDSPESHIGVAHRLKNEIPNSHI LDQYRNASNPLAHYDGTAEEILDACEGKIDMLVSGAGTGGTIAGLARKIKEKVPSCKVIG VDPEGSILAQPEDVTYYEVEGVGYDFIPTVLDRTYVDHWYKSVDKDSFIMSRRMMKEEGL LCGGSSGSAMYSAIQAIKEHDLKEGQRCVVILPDSVRNYMTKFLSDDWMMERDF------ -------LGEYEGERNERDERHGNGKATLPNGDTYEGQYENGKRNGQGTYRFKNGARYIG EYVKNKKHGQGTFIYPDGSKYEGSWVDDQRCG---------------------------- ------------------------------------DRPEGKGKYVFDIGCQQHGEYIXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXSIDALRFQLPPNHKKCLKEEIHKDVLVTGEFELSEAPGQKTTL HVTDSKGHTLYQKEDAKKGKFAFTTEEYDMFEVCFETHMPGGGHGGDREVFLLMKHGVEA KDYQNLAKAEKLKPLEVELKRLEDLSESIVNDFAYMRAREEEMRDTNESTHSRVLYFSIF SMCCLLGLATWQVLYLRRFFKAKKLIE--------------------------------- ------------------------------------------------------------ ---------------------------------------------KDDVVVSATNFTSER MCPIFQVSNVTGENLDLLKMFMNLLTTRIHKEPAEFQIDDTFSVPGVGTVVSGTTLKGCI RLNDTLLLGPDALGQFQPIAVKSIHRKRMTVKEVRGGQTASFSLKKSQIRKGMVMVSPQV NPQACWEFEGEILVLHHPTTISTRYQAMVHVGSVRQTATIMRMSQEHLRTGDKAHVHFRF IKNPEYLRTDMRMVFREGRT---------------------------------------- ------------------------------------------------------------ ----------------------ETGKCYHTFRGHTAEIVCLGFNPQSIVATGSMDTTAKL WDVICTLNGHSAEIISLAFNTTGDRLITGSFDHTVSVWDKRIHTLIGHRAEISSAQFNWD CSLIATGSMDKTCKIWD------------------------------------------- ------------------------------------------------------------ -----------------GDVFMEKHWKSVIHRSICDYFFEVQGKAASPEDVLPVITTPHH YLINIYRNQLYLVAVVTTEVPPLFVIEFLHRVMDTFEDYFQDCTESVIKENHVIVYELLD EVLDNGFPLVMESNVLKELIK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------SQGKYSFDPVGKVMSWDVGKIDPTKLPNI KGSINLQSGAPLPESNPSISVQFTINQMVVSGVKVNRLDMYGEKYKPFKGVKYVTKAGKF QVRT-------------------------------------------------------- ------------------------------------------------------------ -------------------------------------------------EARQQILADLQ DKNLALGIDVDQYNLTENSPMISFKPDPLRVPKKSTTPQNWEDFSRYNVDRANAEMKASQ RLREAIHHTLHQTDNDLEAQ---------------------------------------- ------------------------------------------------------------ -------------------------------------------------TNLRDILTDQI PREQKRVVEFKKAHGSTKIGEVTVDQAYGGMRGIKGLVWETSVLDAEEGIRFRGYSIPEC QDLLPKAEGGAEPLPEGLFWLLVTGQVPTQAQTQALSTEWAERADLPSHVVTMLNNFPSN LHPMSQFSAAITALNSESKFAQAYSEGVHKSTYWEYVYEDAMNLIAKLPTVASIIYRNLY RDGTSVGAIDTSKDWSANFSSMLGYEDAQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSA LSDPYLSLAAAMNGLAGPLHGLANQEVLVWLTKLQVNDDQLREFIWNTLSGGQVVPGYGH AVLRKTDPRYQCQREFALKHLPNDPMFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGV LLQYYGMTEMSYYTVLFGVSRALGCMSQMIWSRALGLPLERPKSMST------------- --VEKCGVCTKSVYAAERIEAGGKPFHKMCFKCSTCKSQLNLNNYAQNDGTLYCKGHFHE AVTSKNLQA----------------------ENLKRVDAIVSNYPVGHERAAVIPVLDLA QRQHGWLPISAMNKVGEILNMPNMRVYEVATFYTMFNREPVGKYFIQICTTSPCILGGVG SDIILDTIVKKLGIKPGEMTKDGQFSLLEVECLGACVNAPMVQINDNYYEDLTPEDMTEI LDDLIAGKVPKAGPRSGQDHRFACEPKGGLTCLTEPPKGPGFGVRTDLMQKYEKLEKIGE GTYGTVFKAKNRESHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHS EKKLTLVFEYCDQDLKKYFDSCNG------------------------------------ ----------------RAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIF AELANAGRPLFPGNDVDDQLKRIFKLLGTATEESWPGISQLPEYKPY------------- --KGRDLLQHLLVCYPNGRMSAEDGMQHPYFADLNPAIK--------------------- ------------------------------------------------------------ ----RSKKKCVTVVQGLATYDINLKEASKFFSNKFSCGASVAAEDEIVIQGDVKDDLWDI IPDKWSQIDEDNIDDLGSRK---------------------------------------- -------------------VQFPEARLIQYDCGKLQTLDVLLRQLKSGDHRVLIFTQMTK MLDVLEAFLNYHGHRYLRLDGTTKVEQRQALMDRFNADKRIFVFILSTRSGGIGVNLTGA DTVIFYDSDWNPTMDAQAQDRCHRIGQTRDVHIYRLISKQTVEENILKKANQKRLLGDVA IEGGNF-----------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXMPSFYRALTPAQETELQSVATQLLRPGHGILAADESP DTISRRF----------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------FWSTIFKNV DMLSEMVQEHDEPILTSLQDIKVNFSMGFTLEFYFDSNEYFTNTVLTKNYVMRSSPDETD PFSFEGPEIIKCTGCTIDWKKGKNVTVKLMKKKQKHKGRGSTRIVTKTVQNDSFFNFFNP PTVPEGEVDEDTEALLAADFEIGHFIRERVVPRAVLYFTGEALEEEEEGEEEE--IILLK EGTDTSQGKPQLISNINACQSIVDAVRTTLGPRGMDKLIVDSQGKATISNDGATIMKLLD IVHPAAKTLVDIAKSQDAEVGDGTTSVVMLAGEFLKQCKPFVEEGVHPQIIVRAFRKATY LLVEKIKEIAVQVKKDPEELRSLLTKCAATALSSKLVAHQKDFFAKMVVDAVMMLDELLP LNMIGMKKCTGGALEDSQLISGVAFKKTFSYAGFEMQPKQYEKPKIALLNIELELKSEKE NAEVRVDTVEEYQSIVDAEWSILYEKLDKIHQSGAKVVLSKLPIGDVATQYFADRDLFCA GRVPEEDLKRTMKACGGSIQTTVQSLTLGTCDNFDEKQIGGERYNVFSGCAKATTCTIIM RGGAEQFIEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKFLRDFSRSIPGKEQLL IGAMAKALEIIPRQLCDNAGFDATNILNKLRQVHAGKWFGVNVTTEDISDNFEACVWEPS IVKINALTAASEAACLILSVDETIKNPRSSHDPGAPGGGRGR--KRNNMIPNAHFHKDWQ RYVKTWFNQPARKQRRRNKRALKAVRIQPRPVGGPLRPVIRCPTVKYNRKLRAGRGFTLE EIKNAGLSFKFARTIGIAVDYRRKNKSQESLQ---------------------------- ------------------------------------------------------------ ---MPNIKVFSGSSHCDLAQKIADRLGIELSKVVLKKFSNQETCVEIGESVRGEDVYIVQ SGCGEINDMLMELLIMINACKIASACRVTAVIPCFPYARQDKKDKSPISAKLVANMLSVS GADHIITMDLHASQIQGFFDIP--------------------------------GAKRVT SNADRLNVEFALIHKERKKANEVAAMVLVGDVKDKVAILVDDMADTCGTVCHAAEKLLEA EAIKVYAICTHGIFSGPAISRLNNSMFERVVVTNTIPQDEKMKHSDKLE----------- -------------------LSCRFYGHKYPEVEDVVMVNVRSIAEMGAYVHLLEYNNIEG MILLSELSRRRIRSINKLIRVGRSECVVVIRVDKDKGYIDLSKRRVSPEEVMKCEEKYAK AKAVNSILRHVGELLEYDSDEKIEELYFKTAWHFDEKYKKPTAAYEVFKLAVSNPEVLDE CDIDDHTKAVLLENINRRLTPQAVKIRADIEVSCFEYEGIDAVKAALRKGLECSTETTPV KINLIAPPLYVVTTTTLDKDEGMARGHQKIQSQQKNAKKLQDAKHDQKKAAAKALIYSCT VCKTQMPDPKTYKQHFENKHPKAPLPDCLKE-MLGTLQTDMSRHGVTTVAKGHCAACNKP IIGQVITALGRIWHPEHFSCAHCREELGTQNFFERDGQPFCERDYHQLFSPRCAYCNGPI LDKCVTALDKTWHPEHFFCAACGRMFGDDGFHEKDGKAFCRDDYFDMFAPKCGGCGRAIM DNYISALNRQWHPECFICQECHMPFGGGSFFDHDGMPYCETHYHAKRGSLCAHCQKPITG RCITAMYKKFHPEHFVCAFCLKQLNK--------------------XXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDREGLLDPAWEKQQRKTF TAWCNSHLRKAGTQIENIDVDFQNGLKLMLLLEVISGEQLPKPDRGKMRFHKIANVNKAL XFIESKGVELVSIGAEEIVDGNVKMTLGMIWTIIVQNFHLSWKDGLAFCALIHRHRPDLI DYNKLSRDNPLHNLNTAFDVAEQHLDIPRMLDAEDMVNSAKPDERSVMTYVSAYYHAFSG AQQAETAANRICKVLKVNQENERLMEEYERMASDLLEWIRRTTPWLENRTTDNTLPGVQR KLEEFRDYRRKHKPPKLEEKALLETTFNTLQTRLRLSNRPAYLPTEGKMVSDIANAWKGL EFAEKGFEEWLLSEMQRLERLDHLAQKFKHKCDIHEEWAFGKEEMLQSMDFKKCKLNELK ALKKKHEAFESDLAAHQDRVEQIAAIAQELNVLEYHDCPAVNARCQRICDQWDVLGTLTQ KRRNALDEAEHILERIDQLHLEFAKRAAPFNNWMDGAKEDLIDMFIVHTVEEIQGLIDAH EQFKQTLGEADKEFNAIIALVNEVQRIAMQYDIVGATENPYTTLSAQDIHNKWGDVRQLV PQRDSLLSQEMIRQQNNERLRRQFAQKANVVGQWIERHLDAIASISMQKGTLEDQLRKLK GYEQEVVNYKPNIDELERYNQDVQEAMIFENRHTQYTMETLRVGWEQLVTSVARSINEVE NQILTRDSKGISDEQMDEFRKSFYHFDKGRTRRLDPKEFKACLISLGYNIRDDRQGDADF QRIMSIVDTNRANYVTFEAFLDFMTRETTDTDTAEQVLQSFKILAGDKSFITPDILRREL PPDQAEYCIQRMAPYSGTGAEPGALDYTSFSTALYGESDL-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------DVGPESTEKFK EVINRAKVIVWNGPAGVFEFEKFANGTKGLMDAVVHVTGNGSTTIIGGGDTATCCAKWNT EDKVSHVSTGGGASLELLEGKVLPGVAALSDAXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXRSRSRSREKARSRSPPKRRKPYKYWDVPPPGFEHITPLQYKAMQAAVP FAGSAISRQARRLYVGNIPFGVTEEAMMDFFNHQMKMTGLAQAEGNPVIAVQINLDKNFA FLEFRSVDETTQAMAFDGINFQGQSLKIRRPRDYQPLPGMSETPSVGVVSTVVQDSPHKI FIGGLPNYLNEDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDQACAGLNGMQLG DKKLIVQRASVGAKNAQQAPVQIQIPGLNLS--PTEVLCLMNMVAPEELMDEEEYEEILE DVKEECGKHGVVRSMEIPRPIKGVEVPGCGKIFVEFNSVIDCQKAQQSLTGRKFANRVVV TSYYDPDQYHRREF---------VQRLAAETKTSSGIMIPEKAQAKVLQATVIAVGPGGR TDAGNLVEPSVKAGDSVLLPEYGGTKVTLNDTEYQLFRDSDILGKFERLKGQVPDIKSTL DIVKHMKTKMDGIKTQFLLSDQLYAKATIPPTDKVCLWLGANVMLEYNLKDAEELLEKNA AQKSLAQVEEDLGFLRDQTTTSEVNMARVFNWDVK-------XXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRSRSRD RDGHKSERKRSRSKDKKDLTPEERDARTVFCMQMSARIRPRDIEEFFSSVGKVKDVRIIT DNKTRRSKGIAYVEFQDTESVPLALGLTGQRLLGVPIMVQASQAEKNRLAGNSGPMRLYV GSLHFNITEDMLRGIFEPFGKIEHINLVMDNETGRSKGFGFVTFHDSEDAKKALEQLNGF ELAGRPMKVGHVTERTAEASILDSDEMDRAGIDLGATGRLQLMAKLAEGTGFQIPQVAAN ALNLNPAQQTPPIATQCFMLSNMFDPTTTQMNWDVEIRDDVIEECTKHGGVLHIYVDKAS PQGNVYVKCPSISAAVASVQALHGRWFAGKVITAAYVPLINYHALFQDAARATAMLLPS- ------------------------------------------------------------ ----LDDNERSDIFDAMFPVHRHAGEVIIQQGDEGDNFYVLDLGEVDVYVNNDYVTTIGE GGSFGELALIYGTPRAATIKAKTDVKLWGIDRDSYRRILMGSTIRRRKMYEEFLGKVSIL ENLDKWERLTVADALALCNF---------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------LRDIIHKFYESKYASCLKLLDEIKENLLLDMYLAPHITTLYTQIRNRALC QYFSPYLSADMNRMASAFNTTVMALEDELMQLILDGQINARIDSHNKILYAKDIDQRSMT FER-----KEYQRRTKALILRSAMLKNQIHVKSPPRDAGQGGEMSIAPGTASS----NEM LDKAEDFADQVLRHSKHILPHVARLCLISTFLEDGIRMWFQWDEQRDYINATWGCGWFLA TLFVITNLIGQLGGCVMVLSRKQVNIACGILFFIIFLQTVAYSILWDLKFLMRNLALGGG VLLLLAESKAEGRSLFAGLPSLGENTPKMYMQLSGRILLVLMFLTLLRFEFSFLQLIQNL IGTALILLVAVGYKTKLSALILVAWLSCMNVYFNAWWNIPDYKPMRDFLKYDFFQTLSVI GGLLLVVALGPGGVSMDE------------------------------------------ -------------------NLLLRTELDLFANVIHCKSVPGIETRHENVDIILIRENTEG EYKQLEHENVPGVVESLKIITEAKSTRIAKYAFDYAVQHNRNKVTAVHKANIMKLGDGLF LECCKKVSESYPNIEFDSMIVDNCSMQMVSKPQQFDVMVLPNLYGNIVNNIGAGLVGGAG ITAGKNLGSDYAVFETGTRNTGKSIMGKNIANPSGMLLASALMLDHLGLFNHGKLIRESV MKVISEDMIHTPDLGGQATTLEVVQAVIKNITEDFQCFLDRSSRVIERAMAQDVDIFTDY SGIDGEGDLQAGEKLKLGRQFFDDHWSKHRTVTCMDWSTQYPELLVASYNNNEDAPHEPD GVCLVWNIKYKKNTPEYIFHCQSAVMSACFAKFHPNLIVGGTYSGQIVLWDNRSNKRTPV QRTPLSAAAHTHPVYCVSVVGTQNAHNLISVSTDGKICSWSLDMLSQPQDSMELQHKQSK VAVTSYSFLSGDVNNFVVGSEEAAVYTACRHGSKAGISDMFEGHQGPITGIDCHTVPGQI DFSPYFLTSSFDWTVKLWSIKENRPLYSFEDNGDYVYDVRWSPIHPALFACVDGMGRLDL WNLNNDTEVPTASTVNCAVNRCRWHQSGHQIAVGDDMGKIHIYDVGEHIANPKSDEWTRF MHTLQDLKNQLADAEDEA------------------------------------------ --------------------------------------------------IIDKHLAILA PKHVETRFVKINAEKCPFLVERLKIVVLPTLCIAKDGKTTDYIVGFDDMGGNDDFPTEMM EWRLGAADVINYSGDITAPPITG------------------------------------- --------------------------------VLGFECAGEVEAVGENVDGFAVGDRVIG FTGAWGELVATVYKMPPGMSFQDGAALPMNYLTAYVMLFEIGNLKKGQSVLIHSAGGGVG HAVAQLCKTVEDVSLFGTAAYKHEAIKNN-VNFLFDH-VVDYAQEIRKVCPEGIDIVLDC LCGEDTNRGIGLLKPMGKYVLYGASSSVTGETKSFLSFAKSWWQVDKINPVKLYDENKTI SGFRLRHLVIMDKLFQLYSEGKIRPTIDSAWPFEDASEAMQKLHDRKNIGKLVLDPSLMS RKQTPSDFLKQIIGRPVVVKLNSGVDYRGVLACLDGYMNIALEQTEEYVNGQLKNKYGDA FIRGNNVLYISTQKRR-MALEQSALLLAKQLSEMKRNPVEGFSAGLIDDDDIYRWEVLII GPQDTLFEGGFFKCHLTFPKEYPHRPPKMKFVSEIWHPNIDKNGDVCISILHEPGDDKYG YEKASERWLPIHTVETILVSVISMLADPNDESPANVDAAKEWRESYTEFKKKVSRCVRKS QEETVRKIDPLVQSDLADFGRYVAECIPKYVQKVQIYNGDELSFMIHPDGVVPVMTFLKD HSQAQFLMITDIAGVDMPSRENRFEIVYMLMSLRFNSRIRVKTYTDELTPVDSINSVFAG ANWYEREIWDMYGVFFANHPDLRRILTDYGFEGHPFRKDFPLSGYVEMRYDDEAKRVVAE PIELAQEFRKFEYNLPWEAFPAHR--LNPFSQVDYRAKLWCCNFCFQRNPFPPQYAAISE QHQPAELIPQFSTIEYTLTRATCNPPVFLIVLDTCMEEEDLQAVKESLQMSLSLLPPNAL IGLITYGKMVQVHELGCEGCSKSYVFRGTKDLNAKQIQEMLGIGKGMGQLPSNRFLQPVH KCDMALTDLLGELQRDPWPVSQGKRPLRSTGVALSIAVGLLECTYPNTGARIMTFVGGSC TQGPGMVVGDELKFPIRSHHDIEKDNCKYMKKAMKHYESLANRTANNGHVIDIYSCALDQ TGLHEMKFACNYTGGHMIMGDSFNTSLFKQTFQRVFSKDVKGEFKMGFCGTIEVKTTREL KVQGAIGPCVSMNMGPSVSDQELGVGGTCQWKMCGIYPNSTLALCFEVVNQHNAPIPQGG RGCIQFITQYQHSSGQKRIRVTTIARNWVDASANVQHLAAGFDQEASAVLMARLAIFRAE TDDGPDVLRWLDRMLIRLCQKFGDYHKDDPNSFRFTEQLSLYPQFMFHLRRSQFLQVFNN SPDETSYYRHCLMVEDLTQSLIMIQPILYAYSFSGPPEPVLLDSSSIQADRILLMDTFFQ ILIYHGEQVAQWRKAGYQDLPEYENFKQLLQAPKDDAQEILQVRFPMPRYIDTEHEGSQA RFLLSKVNPSQTHNNMYADSGAPVLTDDVSLQVFMDHLKKLAVSSSSMANLSHDDQIKLI SDLEVEMMADMYNRMTTACQKKCVPPKYKEAELSKGEAVCIDRCVAKYLDIHDRIGKKLT AMSMQDEEAMKKLQ-AAQPQVIHKVIMVGYGGVGKSALTLQFMYDEFVEDYEPTKADSYR KKVVLDAEEVQIDILDDYAAIRDNYFRSGEGFLCVFSITELDSFQATSDF---------- ------------------------------------------------------------ ---------------KLYTGLREVVTEHLVNKVREDVLTSLNNNFLQTLNRAWNDHQTSM VMIRDILMYMDRVYVQQNSVDNVYNLGLMIFRDQVVRYPVIRDHLRQTLLEMVAKERRGE VVERGAVKNACQMLMILGIDSRSVYEEDFERPFLDQSAEFYRLESQKFLGENSASVYIKK VEARINEEAERATHYLDKSTEEPVIKVLEKELICKHMKTIVEMENSGVVHMLKNNKTEDL GCMYKLFKRVQNGLKTMCDCISGYLREQGKALVAEEETGKNAINFVQSLLDLKDRFDHFL HESYNEDKQFKQMISGDFEYFINLNQKSPEYLSLFIDDKLKKGVKGMTEQDIENVLDKSM VLFRFLQEKDVFERYYKQHLAKRLLLNKSVSDDSEKNMISKLKTECGCQFTSKLE----D MTVSNSTMDEFKSHLTQGTNMEGVDLFVRVLTTGFWPTQSATPKCNIPFAPSTAFESFRR FYLAKHSGRQLTLQPQLGSADLNATFFGPRKEEAESKGGPRKHIIQVSTYQMCILMLFNN RDRLSYEEIKSETDIPERDLLRAIQSLALGKVTQRILYKEPKTKDIEPDHSFSVNDGFTS KLYRVKIQTVAAKGESEPERKETRSKVDEDRKHEIEAAIVRIMKARKRMQHNVLVAEVTE QLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKIYTYVADKLNIFPSRMALTAMKSRLK GAQKGHSLLKKKADALTMRFRQILRKIIETKSLMGEVMKEASFSLAEAKFTSGDFSHMVL QNVNKAQIKVRSKKDNVAGVQLPIFEHYADGTDSYELTGLSRGGQQIDKLKKNYGKAVEL LVALASLQTSFVTLDEVIKITNRRVNAIEHVIIPRIERTLAYITTELDEREREEFFRLKK I----------------------PLRVLVTGAAGQIAYSLLYSIAKGDVFGSSQPLSLVL LDISPMLGVLQGVVMELQDCALPLLQEVIPTDDPAVAFKDIDSAILVGAMPRREGMERKD LLKANVGIFKAQGKALDQFAKKTVKVVVVGNPANTNALICSINAPSIPKENFTCLTRLDQ NRAQAQVAAKEAVQNVTIWGNHSSTQFPDVVHAKAVYDAVKDDNFLKNEFISTVQQRGGA VIKARKLSSAMSAAKAIGDHMRDWFVGTKPGQWVSMGVPSNGYGIPEGIIYSFPVAIDRT YSIVEGLSISDFAREKMDATMKELVEERDMALES-------------------------- ------------------------------------ELGQAEGVPQVYYFGPCGKYNALV IELLGPSLEDLFDICDRKFSLKTVLMIAIQLLSRMEYVHSKHLIYRDVKPENFLIGRQSN KK---------------------------------------------------------- --------------------------------------------------------RRLD FFETPDYDYLRKLFTDLMEKKGWESDWEFDWTGRTVHPTTTNKVVSSTNGELAPTAGHSN TPIAAQPEVEVVDETKCCMTTLRSFTCDDMFKFNNVNLDPLTETYGLPFYMQYLAHWPEY FQVAESPSGEIMGYIMGKAEGHGDNWHGHVTALTVGPEFRRLGLAANLMNILEKISDKKF CYFVDLFVRVSNK----------------------------------------------- ------------------------------------------------------LKIARD KNSGKDYLLCDYNRDGDSYRSPWSNTYDPRLEDGAMPSDRLRRLEIEANAAFDQYREMYF EGGVSSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRSAHYKLTST AMLWLQTNKSGSGTMNLGGSLTRQAEADCNVSEASPHIANIGRMVEEMENKIRNTLNEIY FSKTRDIVNGLRSIVPLKQDMLRNDLAAALQKRQQ-FDDIDEVDEALDEVDQDEKIDILA SDQRVEPQKRITTPYMTKYERARVLGTRALQIAMCAPVMVELEG---------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------WMLHAGVMGAVIAPLTLLGGPLLVRAAWY TAGVVGGLSTVAMCAPSEKFLNMGGPLAIGLGVVFASSIGGMFLPPTTALGAGLYSISMY GGLVLFGMFLLYDTQRIIKHAETHPVGYVKPFDPVNHSISIYLDTINIFIRIAMIMAG-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------VCDESLLSLRVQEQGRLIACGSHSGTTTL LELSDGLCNLQRNEKALVTAMFERETRREKILEARHREMKLKE----------------- ---------------IKKALRKGVREVQKFIRKGEKGIVVLAGDTSPVDVICHMPFVCEE GSIPYCYAPSKEDLGAACGSRRPTCMVMIKKHDDYEDLFQECSTDVSALPLPI------- ------------------------------------------------------------ ---------NSTQLKKFDEKIEDAEKNLGETEVREFMLEKAEYLCRIGDKDGSLTQFRKT AEKTVTLGYRLDIVFHQIRMGLFYMDHDLITRNLEKAQTMMDEGGDWDRRNRLKVYRGAY CMAIRDFKKAANLFLDTVATFTSYELMDYKAFVAYTVICSMIALERPKLRKQVVHGSEIL EVLHSSPKVKDYLFSLYNCQYGQFFTSLAYI----------------------------- ----RSLTLDYMANAFGVTVNMVDQELSRFIADGRLHCKIDKVGGIVETNRPDSKNWQYQ ESIKKGDVLLNRVQKLSRIINISRGLKNSSEQIAGIPYKNLTIGVPKEIFQNERRVAIVP ATVAMLKKGFTFNVEDSAGVLSKFNNEAYTEAGANISKEEAYKSDIVLKMRAPLLEEVPL LRERGNLISFIYPAQNKELVDAIAQKKMNVFAMDCVPRISRAQVFDALSSMANIAGYKAV IEAANHFGRFFTGQITAAGKIPPAKIMVIGGGVAGLSSIGTAKNMGAIVRGFDTRPEVKE QVESLGAEFLEVNIKESGTGVGGYAKEMSPEFIAAEMALFAKQAKDVDIIISTALIPGKK APLLIKKEMVESMRPGSVVVDLAAEAGGNIETTVPGELSVHHGVTHIGYTDLPSRLPTQA STLYSNNISKLLLSFGFNINLEDEVVRGSIILKEGEMMWPPPAPPPPNYFMNTFKDSMTY SAGLGSIITLGMVSPNAAFTTMVTTFGLAGIVGYHTVWGVTPALHSPLMSVTNAISGITA VGGLLLMGGGYLPSNTAQALAVTAAFISSINICGGFFVTQRMLDMFKRPDDPPEYNY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------TTALSSVMGVTLTAAIGGADMPVVITVLN SYSGWALCAEGFMLNNNLMTVVGAMIGSSGAILSYIMCKAMNRSLPNVILGGYGISA--- -AKIDIQGEHKEI----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------DQILIHQQVELFEALTDIEMKNRYQMKNSLGQQFAFAK EESDTCMRICCGPARGFLLHITDNLGQEIMMIRREFKCCAGCCWCIGCSLEIYIESPPGN VIGSVKQQAWKAVYGVFNEIFKILGPCCICECPCA--SVDFKIHAQVVGTISRQWSGLMK EMFTTADNFGVQFPMDLDVKMKAVLIGATFLIDFMFFENKNNGGDKELQEFLMMEQQKAQ FQTQIHTLANVCWDKCMGKPGNYMDSRTETCVSNCVERFIDTSLQISQRFQQMLQQ---- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------VEKGVCTTEKQNFLLFDMTTHPLTDNSSKQKLIK KVQDAVLSRWTNNPQRMDRRMLSLIYLAHASDVLENAFAPLSDEDYEVAMKRVRELLDLD FEQEAMKEGANELMWCIISAFSK--------EEDCEVCVKFLTRFAESLTTVEKKFRETC KTVKKREERFCYYIGGLETSATGMLGEMSKPISWGMPALKVCEKLEKKDAQ--------- ----------------------------------------------------XXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX--------------------------------------------- ------------------------------------------------------------ -------------EATPDIYSQVAKPKKVTLTKHTKNMGKFSSVTVSTVDEEEEELEAKE IADSYAANARVIEKQLLRKGISKRKLMEQAEEERKKMRTKGTLID---------AQQQNR GYAEMAFTFASPAEVNVKQVDVPSFSGSFGILPEHVPLLAVLQPGVLTVIEEDGVSNKYF VSSGSVTINDDSSVQILAEEAAPLDRLDQHAIREGLAKANQEMTTDVAKAEAQISQECFE ALSKASEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------- ----------------------------HTLQDFQNVLNVNTSGTFNVTRLAVGLMGKNE PNENGQRGVVVNTASVAAFDGQCGQVAYSASKGGIVGMTLPLARDLASQGIRV------- ------------------------------------------------------------ -------------------------------VVGAGGAGLRAAFGLANEGFKTACITKLF PTRSHTVAAQGGINAALGNMEEDDWRYHFYDTVKGSDWLGDQDAIHYMTEQAPKAVIELE NYGMPFSRLENGKIYQRAFGGQSINYGKGGQAHRCCAVADRTGHSLLHTLYGRSLHYDTD YFIEYFALDLIMEEGECRGVLALCLEDGTIHRFRSKNTVIATGGYGRSYFSCTSAHTCTG DGTAMVSRAGLANEDMEFVQFHPTGIYGAGCLITEGCRGEGGYLINAEGERFMERYAPTA KDLASRDVVSRSETIEIREGRGCGPDKDHCLLQLSHLPPEQLHERLPGISETAMIFAGVD VTRDPIPVLPTVHYNMGGVPTNWKGQVIKIGGSDVIVPGLYACGEAACASVHGANRLGAN SLLDLVIFGRACATTITEENRPGEAIGEIKDNAGEESIANLDKLRYSNGDISTAELRLKM QKTMQTNAAVFRDGPTLKEGCELIADQYKDMNLKVTDRGLVWNSDLVETLELQNLMINSV QTVVSAEARKESRGAHAREDFQIRLDEYDYSKSTEGQKKKPFKEHWRKHTMSHVN----- ----------------------------MTALTQEEIISNTKTVVQGLDTLKNEHHQILN SLLSSMKTIKKGDTNLVEEKTNILKKSQEMIELGLGEAQVMMALANHLQHVEAEKQKLRA QVRRLCQENAWLRDELANTQQKLQLSEQKVATLEEEKKHLEFMNEMKKYDSDDNLGFPED DDDQSQSAMAQAASGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHD HPDVATMLNILALVYRDQGKYKEAANLLNDALGIREKTLGPDHPAVAATLNNLAVLYGKR GKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEQYYQRALEIYE TKLGPDDPNVAKTKNNLASA--XXGKYKQ------------------------------- ------------------------------------------------------------ ---------------------------------------------------LQAGSNRGA SQCMGGQRHVADLKNLRMSQDSECVIGLQAG--GASQTGMSMGGVRHVSDLKVDKMAADS QSIIGLQAGSNRGASQSG---------------------------------------IVY GGQRHAGD---------------------------------------------------- ----------------------------------------------------------MA EILRFGVKPITCHAWNGDRTKIAIPNNHEVHIYKLSWVLEDTLQEHAQKVTSIDWAAQSN RIVTCGADRNAYVWPTLVILRINRAATCVKWSPLENKFAVGSGARLISVCYFEKENDWWV SKHIKKPIRSTICSLDWHPNNVLIACGSSDFKARVFSGYIKEVDEKPGPTDWGKKMTFGN LMAEFSNG---------------------------------------------------- ----------------------------------QTLDKRAVKLNSKHQNTITDINIHTG SKSDTRKFSTSGIDGLLVNWDIK------------------------------------- ------------------------------EVDSTQVVLKENGVQLRLTVVDTPGFGDAV DNSNCWQPIVDFIDNKYEEYLNSESRVNRTSFNDNRVHCCLYFIAPNGHGLKPLDVEFMK RLHDKVNIIPLVAKADTMTPDECREFKKTILNEIAQHKIKIYEFDDEEEKKAQKKLKDRV PFAVVGSNTVVESSGRKVRGRIYPWGVVEVENLEHNDFIALRNMLVRTHMQDLKDVTNNV HYENYRYQKLAPVTKNPLAQMEEEKREHVQKMKKMEAEMEQVFEMKVKEKKQKLKDSEAD LQRRAEQMKKSLEQQSRELEEKQKQFDKERIQWEE---MSRRYDSRTTIFSPEGRLYQVE YAMEAIGNAGTCLGILASDGVVLAAEKKTTNKLLDEVFASEKIYTLYEDMACSVAGITAD ANVLTNELRLISQRYTLQYQEPIPCEQLVSTLCDIKQAYTQFGGKRPFGVSLLYMGWDKH YGFQLYQSDPSGNYGGWKATCIGNASASALSLLRQEYKE-DTTLKDALELSIKVFHQSLD MTSLTSDKVELATLTRVDGKTQIKILNNEEVDRVIKKIKEDEAKAEKKKE-ELNEAWQRL RQLALKRQERLFGAHEIQHFNRDADEAIAWIVEKDAMLSTDDYGRDLASVQALQRKHEGV ERDLAALEEKVNALSSESERLTQTHGDQAEQIQAKRDEIENNWQRLSSKAQERKVRLDDS YNLHRFLADFRDLVSWINDMQTIISADDLAKDVPGAEALLERHQEHKGEIDAREDSFKAT AEAGQRLLESDHYAVEEVKEKLVVLANEKTSLLQLWEERRILYEQCMDLQLFLRDTEQAD AWMAKQEAFLQNEDLGDSLDSVESLIKKHDDFEKSLAAQEEKIKALDEFATKLIENDHYA ADEVAHRRDALLTRRNNLHERATIRRRELEESRKFQMFERDCDETKGWINEKLKTASDEG YMDPTNLQGKVQKHENFAAELSANAPRIEAVNQNGQELIEADHYAKDTIKEDLDEIMGLW QKLVDQSDRKGAKLKEASEQQQFNRNIDDVEIWLNDIEGQLVSEDYGKDLTSVQNLQKKH GLMESDVLSHQDRFDGIIAQSATFVEAGHFDKDNIQSKAGVVAQRYQQLLNPLTGRKQKL VEALSLQQFFRDVEDEEDWIREKEPIAASTNRGRDLIGVQNLMKKHQALQAELAGHESRI DAVGEQGEQMIREDHFAAEEIKHKMEGLLARWEQLKEKSNQRKQDLEDSLQAQQYFADAN EAESWMREKEPLVGSTDYGKDEDSAEALLKKHEALMADIEPYRSSIETLKEEATSCKQQE APVIDDIGRECVVALYDYTEKSPREVSMKKGDVLTLLNSTNKDWWKVEVNDRQGFVP--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AWIKEKKLLVGSDDYGRDLTG VQNLRKKHKRLEAELASHEPAIQAVQDIGEKLMAESNIGTEEIESRLRQLSENWEELKQM TSTRGQKLEESLTYQQFAANVEEEEAWITEKQHLLSGEDYGDTLAAVQGLLKKHDAFETD CQVHQDRANEIKKEGEKLISEGNHNADNISVRCTSLQSKMDTLLEAANRRKSNLIDNSAF LQFIWKTDVVESWIADKETQVRSDDYGRDLSSVQTLLTKQETFDAGLQAFEKEGIQTITS LKEQLISSNHAQTAAIEKRYSDVITRWQKLLADSEARKQRLLRLQEQYRQVEDLYLTFAK KASAFNSWFENAEEDLTDPVRCNSVEEIKALREAHDQFK--LSAAQADFNQLAALDKQIK SFNVGPNPYTWFTMEALEETWKNLQKIIKERDGELAREQQRQEENDVLRKQFAQAANAFH GWLTETRSAMMEGSGTLESQLEATKQKAVEVRAQRSQLKKIEDLGASMEERLILDNRYTE HSTVGLAQQWDQLDQLGMRMQHNLEQQIQARNTSGVSEDALREFSMMFKHFDRDKTGKLD HREFKSCLRALGYDLEVKEEGQDDPEFQAILDSVDPNRDGQVSLQEYMAFMISRETENVQ SSEEVEQAFRALTSGEKPFITSQELYSNLTKEQADYCISRMK------------------ --------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIDKNDHENPQ LVSEYVNDIYEYMRQLEVEAINPRMRAILVDWLIQVHLRFHLLQETLYMTIAVLDRFLQE EVSRTKLQLVGVTSMLIASKYEEMYAPEIADFVYITDNAYSKSDIRKMECMILKTLDFNL GRPLPLHFLRRNSKAGQVDANVHTLAKYLMEMTLPEYSMVHIHPSQIAGAGLCLAMKVLQ WDDTLTHYSKYSEKELKPIMQKMAHLIVKKLTAVKSKYQSSKFMKISTIPQLKGRLVKEL A----------------------------------------------------------- --------------------------------SDDNGQDLSTYNFATDGFHAAATNNLCL ATGVRGGVDWMRKLAFRYRRIKEIYNSYRNNVGGLLGPQKREQWLQLRSEIEALTDSWLT LALKSLTIINSRSNCVNVLVTTTQLVPALAKVLLYGLGGVFNIENVYSATKIGKESCFER IVSRFGRKCTYVVVGDGRDEEAASKQMNWPFWRISNHSDLAALHHALDLGYL-------- ------------------------------------------------------------ ----------------------SVVIIAAELLKSADELVKCKIHPTSIISGYRLACKEAC RYIQDHLTIKTDDLGRECIINCAKTSMSSKIIGPNSDFFANMVVDAAMAVKMSDGKGGTK IPIKAVNVLKAHGKSARESMLIDGYALNCTIASQAMPKRITNAKIACIDFSLNKAKMKMG VQVLVEDPEKLDAIRQRESDITKERIEKILATGANVILTTGGVDDLCLKYFVEAGAMAVR RCKKSDLKRIAKATGATFVLTLCNLEGEETFDAAYLGSAEEVIQERISDDELLLIKGPKA RTASSIILRGANDFMCDEIERSVHDSLCVVKRVLESKSIVPGGGAVEAALSIYLENYATS MSSREQLAIAEFANSLLVIPKQLGVNAAQDSTELVAKLRAYHNMSQTKAEHADLKWIGLD LHEGIVRDSKKAGVFEPAISKIKSLKFATEAAITILRIDDMIKLHPEQQGGPSYAQAQAA GML----------KNILNQLAVEGKDLTVEYKIYNVGSSSAINVMLSENGFPETDFEVVH GNLQVRWERIAPESNVSHAVILRPLKSGFFNFSSAEVKYLADEDDPVVGYTSAPGEGGIM PNRDYDRKFSPHLLDWATFALMTVPSLGFPFIFWYRSSCKYNTVSTKKS----------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---LQEFSVYLQPHQKAVTSDGSTILDRAVIEHNLLSASKLYNNISFEELGALLEIPPAK AEKIASQMITEGRMNGYIDQIDSIVHFEAREALPSWDKQIQNLCLQVNDIIEKISQNAPE WMAKAMDEQM-------------------------------------------------- ------------------------------------------------------------ ------------------------------NCQGLMHLPARPVAAFDPEGLIFAAGINSE SIKLYDLRSFDKGPFATFKLQQDKGCDWTGLKFSPDGKLILISTNGSVVRLVDAFQ---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -IAAVNGFALGGGCEVAMMCDIIYAGAKAKFGQPEITLGTIPGAGGTQRLTHAIGKSKAM EMVLTGNMINAEQAEKAGLVAKVFPVDQLVDEAVKTAEKISSMSKLTTGMAKESVNAAYE LSLKMGLQYEKRLFHASFATHDRKEGMAAFSEKRPAEFKD >Malacoceros_fuliginosus MTDRKAVIKNADMSEDMQQDAVDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSG-----RQFQTSASVRDIDQAAKYIGAGAATV GAAGSGAGIGSVFGSLVIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLILFAFM SHYKE-GKAPESTIHRIRITLTSRNVKSLEKVCADLIRGAKDKQLKVKGPVRMPTKVLRI TTRKTPCGEGSKTWDRFQMRVHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX X----------------------------------------------------------- ------------------------------------------------------------ -------------GCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPVNDYIDSAVRHVLLRQ GVLGIRVKIMLPWDPSGKIGPRKPLPDHVSIVEPKDESRIDAPYSEQKGGKMSKRGRGGA SGGKFRITLALPVGAVMNCADNTGGKNLYIIAVNGIRGRLNRLPTAGSGDVVLATVKKGK PELRKKAMPAVVIRQRKSIRRQNGVFIFFEDNAGVIVNNKGEMKGSAITGPVAKECADLW PRIASNASSI-------------------VFGVAHIFASFNDTFVHVTDLSGKETIARVT GGMKVKADRDEASPYAAMLAAQDVAERCKVLGITALHIKLRATGGNRTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRLMGKPRGLRTARKQRDHRRDQRWHDKD FKKSHLGTRWKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP RDGCLNYIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVASVSLLALYKEKKERPRS--- -SIRTRKFLTNRLLCRKQMVVDVLHPGHATVSKTDVREKLARMYKTTPDVVFAFGFRTNF GGGKTTGFGLIYDSLDFAKKFEPKYRLARHGARKQRKERKNRQKKVRGTKKAKIG-MPRI PTVRSKTYTAPRRPFEKERLDHELRLIGQFGLRNKREVWRVRYTLAKIRKAARELLTKEE KDPKRLFEGNALLRRLVRIGVLDEDKMKLDYVLSLRMEDFLERRLQTQVFKTGLAKSIHH ARVLIRQRHIRVRKQVVNVPSYIVRLDSQKYIDLAHDSALAGGRPGRVKRKNAKKGQGGG GDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMPLAKDLLHPSLEEEKRRCKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRRKQHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXX-------------------------------------- -------------------LHVHGHFVSDVVMSSDGQFALSGSWDKTLRLWDLSEGTTTR RFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIEDTHSEWVSCVRFSPNT QNPIIVSAGWDKLVKVWNLTNCKLKTNHFGHHGYLNCVTMSPDGSLCASGGQDGSAMLWD LNEGKHLYTLDGGDIINALTFSPNRYWLCAATGPSIKIWDLEGKIVVDELKPEVISTSAD PPNCISLAWSADGQTLFAGYTDNLIRVWQVSM---XXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSALPMNPKPFL NGLTGKPIMCKLKWGMEYKGYLVSVDGYMNLQLANTEEYIDGALSGNLGEVLIRCNNVLY IRGVEEDDEEGEMKEMSDEERDDIPQAPAAGGPMDVNTALQEVLKSALIADGLARGLHES AKALDKRAAHLCVLANNCDEPMYVKLIEALCAEHSIQLIKVDDNKKLGEWAGLCKLDKEG KARKVVGCSCVVVKDYGKESQAHDVLHEYFKSRKXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFSGSAKIIKPNGEKPDDFESSISQ ALLELEMNSDLKAQLRELYITGAKEIDVAGKKAITIFVPVPQLRAFQKILTRLVRELEKK FSGKHVVFIAQRRILAKPTRKTKRKNKQKRPHSRTLTAVHDAILEDLCFPAEIVGKRIRV KLDGSRLIKVHLDKTQQTNVEHKMDTFSAVYKKLTGKEVAFEFPEYVL------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------QVTGKCGSVLVRLIPAPRGTGIVSAPIPKKLLNMAGIEDC YTSACGQTATLGNFAKATYSAISKTYGYLTPDLWKDTVFCKAPYQEFTDFLMK------- ------------------------------------------NLRKTWEKLLLAARAIAA IENPADVCVISARQYGQRAILKFASYTGATPVAGRFTPGTFTNQIQAAFREPRLLVVTDP RTDHQPVTEASYVNIPVIALCNTDSPLRYIDIGIPCNNKSSHSIGLMWYLLAREVLRLRG TISREVPWDVMVDLFFYRDPEEAEKEAEMTDWATDTVVPAVPMATDDWSAAETGDWAAST PTSDWGGMKFNTMVSSSRRKQRCRHFNAPSHIRRKIMSSSLSKELRTKYNVRAMPIRKDD EVQVVRGHYKGQQVGKVVQVYRKKFVVHVERIQREKANGASVHVGIHPSKVVITKLKLDR DRKEILDRKAKSRQLGKYTESQ----SATNVGTTVRNRKPAASGAGAAGMWRFYTEDSAG IKVGPVPVLVMSLLFIASVFMLHIWGKYTR-XXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------------ ------------------------------------------------------------ ----------------------------D-DDDEVPDLVENFDEPSKAEMARYSLNPENA NKSAKAHGSHLRVHFKNTHETAHFIKGMALARAVRYLKNVKEKKEIVPFLRFNGGPGRHA QAKNVHASQGRWPKKSAEFLLQLLKNAESNAEYKGLDTDHLMIEHIQVNRAPKMRRRTYR AHGRINPFMSSPCHIEVILAERETVVAKPAKKKVSQKKLKKQKLKM--XXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXMGISRDKWHKRRKTGGRMPQLRKKRKFELGRPAANTKIGE QRIHTVRTRGGNKKYRALRLDHGNFSWGSEAVSRKTRVIDVMYNASNNELVRTKTLVKSC IVAIDATPFRTWYESHYTVPLGRKK-AKLTKEEEEIFTKRSKKCQKKYDERKKEAKVEQA LEEQFATSKLLACVASRPGQCGRCDGYILEGKELEFYLRKIKAKKGKMSLVIPEKFQHIL RVMNTNIDGRRKTPFAMTAIKGCGRRYSTLVCKKADVDPTKRAGEMTEDEVEKVVTIMSN PRQFKIPDWFLNRQKDVKDGKYSQVMSNTLDNKLREDLERLKKIRNHRGLRHYWGLRVRG QHTKTTGRRGRTVGVSKKK--------------------------------------EEA RKALSKLGLKQVTGVTRVTIRKSKNILFVINRPDVYKSPASDTYIVFGEAKIEDLSTQAS MQAAEKFKAEEEIEESGIEEKDIELVKSQANVSRAKAIKALKNNQNDIVNAIM------- -----------KYYTRLTMDFHTNKRVCEEIAIIPSKRLRNQVAGFVTHLMKRIRAGPVR GISIKLQEEERERRDNYVPEVSAIEEVDPDTKEMLKMLDFNNIPGLQVTAPITSTXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------- ------------------------------------------------------------ -----------------NFSDTGNFGFGIQEHIDLGIKYDPGIGIYGMDFYVVLGRPGFN IAKKKRKTGRVGFQHRCTKDLAMKWFQSKYDGVILPGK---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------QQMVMRGHREKSMIHELNRYIPTAAAFGGLRIGALSVVADFLGAIG SGTGILLAVTIIYQYFEIFVKEQSEMGGMGTLLF-------------------------- -IGLGFRTPR-AIDGTFVDKKCPFTG-VNIRGRILTGVVQKLKMTRTIVPRRDYLHYVRK YNRFENTHI-ISAHCSPAFRDVAAGDVVTGSECRPLSKTVRFNVIKVTRAAGSWK----- XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRVIRAQRKGAGS VFRSHNKHRKGAAKLRSVDYAERHGYIKGIVKDIIHDPGRGAPLAKVNFRDPYRFKLRSE TFIASEGMYTGQFIYCGRKANLQIGNVLPVGQMPEGTIVCNLEEKMGDRGRIARASGNYA TVVSHNPDTRRTRVKLPSGSKKVIPSNNRAMVGIVAGGGRIDKPMLKAGRAYHKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGHASTVRRDTAAGRKVGLIAARRTGRLRGSKQVTG KXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRRPARCYRYCKNKPYPKSRFCRGVPDS KIRIYDLGRKRARVDDFPLCIHLVSDEKEQLSSEALEAARICANKYLVKSCGKDAFHMRV RPHPFHIVRINKMLSCAGADRLQTGMRGAFGKPQGTVARVKIGQSILSVRAKISNKEPVI EALRRAKFKFPGRQKIHVSRKWGFTKWDREVYEPMRAAGTLVPDGVTVQYKPNKGPLQAW KNAQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------- ------------------------------------------------------------ -----------------LPSTAEERARRICRGLRVLNVYRVGEDSTYEFYDIIMVDPFSK TISXDPSLNWICAATKKHHKIRSLTSATPKSRGLGKGHKFHKTMGGSRRAHWKNNNTF-- ----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXLGFAENFALSGAAAVISKTAAAPIERVKLLVQNQDEMIKQGRLDKPYKGVIDCTM RTLKTEGVIPFWRGNLANCIRYFPTQALNFAFKDKIKALFGSKKTDGYGIKFGKNVASGG AAGAMSLCFVYSLDYARTRLANDAKG--KRMYNGLVDVYKKTLATDGIQGLYRGFVISCV GIVVYRGCYFGFYDTLKPIVLGENAGLMLSFALGYVVTISAGLVSYPIDTIRRRMMMTSG QAVKYNGSVDCFVKICKAEGFMSLMKGAGANILRGVAGAGVLSGFDKFKEVYISWRLXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXMVRGPRKHLKRLNAPKHWMLDKLGGTFAPRPSCGPHKLRECLPLMVFLRN RLKYALTYQEVVKIVNQRLIKVDGKVRTDKTYPAGFMDVITIEKTSQNFRLIYDVKGRFT VHQITPAEAKYKLCKVRKVSVGPKGVPYIITSDGRTIRYPDPLVKVNDTIKLXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXX-------------------------------------- -------------------------------------------------RARIECQSHRL TVEDPVTLEYVTRYIAQLKQKYTPSNGRRPFGLSALIMGFDGSPHLYQTDPSGTYHEWKA NAIGRSAKTVREFLEKHYSPEVATERETIKLALKALLEVVQSGSKNMEAAIMLKGEALTM MKSEDIETYIREIEKEKDEEAEKKKHKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMKLNISYPATGCQKMIEMDDEKKVRAFYEKRMASEVSAESLGDEWKGYIVRISGGND KQGFPMKQGVLTAGRVRLLLSKGHSCYRARRSGERRRKSVRGCIVDAQLSVLNLVIVKKG ENEIEGLTDSTVPRRLGPKRASRIRKLFNLSKEDDVRQYVVRRPLPPQTKAPKIQRLVTP LVLQRKRHRLALKKRRAAKKRDDAAEYAKMLAQRMKEAKERKAERRRSASQSKXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--KKVQLKFFID CTHPVEDGIMTCEDFVKFLQERVKVAGKTGNLKTKVVLTAEVAFSKRYLKYLTKKYLKKN NLRDWLRVVANTKDAYELRYFQINNEEDEEDADEXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSMRRP FDPVAHELDASFRLTKFADLKGGCKVPQEVLLKLLEGLQESAEGQQSNFQYVAAVPRIGI GMDSCVTPLRHGGLSLVQTTDFFHPLVDDPYMMGKIACANVVSDLYAMGVTECDNMLMLL GVSQKLTEKERDVVLPLMMRGFRDTAEEAGTSVNGGQTVVNPWMTIGGVATTVCQPNEFI MPDNAVVGDVLVLTKPLGTXVAVNAYQW-------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXTAPFDARFPNQNQTRNCWQSFVDFHRCHKVEDYE PCDYFKRVYSSPCPNEWTSKWDEQLEKGAFAGKIXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------- ------------------------------------------------------------ -----------------------DFIKNMITGTSQADCAVSIVAAGVGEFEAGISKNGQT REHALLAFTLGVKQMIIGVNKMDSTEPNYSEARFTEIKKEVTGYIKKIGYNPDAVPFVPI SGWHGDNMLNMKWFKGWSCTTGKTLLQALDNISPPSRPTDKALRLPLQDVYKIGGIGTVP VGRVETGIIKPGMVVTFAPPMVTTEVKSVEMHHTALEKAEPGDNVGFNVKNVSVKDIRRG NVCGDTKADPPQGCSNFKAQVIILNHPGQIGNGYAPVLDCHTAHIACKFRELIEKIDRRS GKKLEDNPQFVKSGDAAIVDMVPQKPMCVEAFSDYAPLGRFAVRDMRQTVAVGVIKAVTK KEKSDGKVTKAAQKAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMSKLNRDTVSEAIDTVLKKKRKFTESVELQIALKNYDPQKDKRFTGTVKLRSIPKPK MKVCVLGDQQHVDEATANEISCMDADALKKLNKNKKLVKKLAKRYDAFLASDTLIKQIPR LLGPGLNKAGKFPTMLTHSESMVNKVDEVKATIKFQMKKVLCLAVCIGHVNMTKEELQMN IILAVNFLVSLLKKNWQNVRSLYIKNTMGPAQRIYXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXX----------------------------------------------- -------------VVEHSEYGEVIQLQGDQRKNVEGFLVELNFPDKLKVHGF--VYSFDG LVVFGLIFVCTCAYMKRV-PKLLLSEKKGFMGVFYKASVIGTRLHIATAASCIIMSLYVL FI---------------------------------------------------------- ----------------QNIQAEDTFKFSSGLKGMALNL-PDNVGIVVFGNDKLIKEGDIV KRTGAIVDVPVGEELLGRVVDALGQAIDGRGAITGSGRARVGVKAPGIIPRISVKEPMQT GIKAVDSLVPIGRGQRELIIGDRQTGKTAVAIDTIINQKRFNDQGNEKAKLYCIYVAIGQ KRSTVAQIVKRLTDADAMKYTIVVSATASDAAPLRYLAPYTGCAMGEFFRDNGKHALIIY DDLSKQAVAYRQMSLLLRRP---------------------------------------- ------------------------------------------------------------ -------------------------------XGVRLTYLLKQGQYVPMAVEDQVCIIYAG VRGMLDKVDPAKITTFEAEFLAHIRSSHTDVLTSIRD----------------------- XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX >Marphysa_bellii MSDRKAVIKNADMAEDMQQDAVDCATQALEKYNIEKDIAAFIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSG-SLQMRQFQTSAIQRDIDQAAKYIGAGAATV GAAGSGAGIGSVFGSLVIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLILFAFM SHYKE-GKAPEATIHRIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKILRI TTRKTPCGEGSKTWDRYQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADMDQVM QFLEPAKTFSKDSIRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNII VMAVSMSKKRKFVADGVFKAELNEFLTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVL GEKGRRIRELTSVVQKRFNFPEGTVELYAEKVATRGLCAIAQAESLRYKLIGGLAVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGEPCNEYVDTAVRHVLLRQ GVLGIKVKIMLPWDPTGKIGPKRPLPDHVSIVEPKEEVLPAQPYSDQKGAKMSKRGRGGS AGGKFRISLALPVGAVINCADNTGAKNLYIIAVHGIKGRLNRLPAAGSGDMVMATVKKGK PELRKKVMPAVVVRQRKAIRRRDGVFIYFEDNAGVIVNNKGEMKGSAILGPVARECADLW PRIASNAGSIRKGKVAKVSLGPQVVEGENVFGVAHIYASFNDTFVHVTDLSGKESIARVT GGMKVKADRDEASPYAAMLAAQDVAERCKTLGITALHIKLRATGGNKTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL-GKPRGLRTARKLRDHRRDQRWHDKD YKKSHLGTRWKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP RDGCLNYIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKEKKERPRSESI VTLRTRKFLTNRLLCRRQMVVDVLHPGKATVPKTEIREKLARMYKTTPDVIFVFGFRTQF GGGKTTGFGLVYDSLDFAKKFEPKYRLARHGTRKQRKERKNRQKKVRGTKKAKVGA--RV PMVMSKTYMTPRRPFEKERLDQELKIIGEYGLRNKREVWRVKYTLAKIRKAARELLTLDE KDTRRLFEGNALLRRLVRIGVLDEGKMKLDYVLGLRLEDFLERRLQTQVFKLGLAKSIHH ARVLIRQRHIRVRKQVVNIPSFVVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGTGGG ADMGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIGEAREELMRMLAEDELRD AVLLCFANKQDLPNAMNAAEITDKLGLHSLRQRNWYIQATCATTGDGLYEGLDWLSNQLK NQKMPLAKDLLHPSIEEEKRKCKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRKKAHMVRMNVLADALRSICNAEKRGKRQVLIRPCSKV IVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDIALRDMEKWTTNL LPSRQFGYIVLTTSGGIMDHEEARRKHLGGKILGFFFMGRMHAPGKGISQSALPYRRSVP TWLKLSSDDVKEQIKKLAKKGLTPSQIGVILRDSHGVAQVRFVSGNKILRILKGMGLAPE IPEDLYHLIKKAVAIRKHLERNRKDKDSKFRLILVESRIHRLARYYKTKKVLAPNWKYES STASALVAVAEIPEVKLFGRWSSDDVQVGDISLADYIAVKEKYAKYLPHSAGRYQVKRFR KAQCPIVERLTSSLMMHGRNNGKKLLTMRIVKHAFEIIHLLTGENPLQVLVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREASFRNIKTIAECLADELINAAK GSSNSYAIKKKDELERVAKSNRMQEQMTLRGTLQGHGNWVTQIATTPQYPDMILSASRDK TLIMWKLTRDTNYGIPQKSLKGHGHFVSDVVMSSDGQFALSGSWDSTLRLWDLSTGETTR RFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIEDGHSEWVSCVRFSPNT QNPIIVSAGWDKLVKVWNLTNCKLKTNHHGHTGYLNCVTVSPDGSLCASGGKDGQAMLWD LNEGKHLYTLEGGDIISSLCFSPNRYWLCAASGASIKIWDLEGKVVVDELRQEVISTNAL PPQCTCLAWSADGQTLFAGYSDNLIRVWQVSMATRMREYKLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKVVEVDGNQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKLARQFNCAFLETSAKSK INVNEIFYDLVRQINKKNPEQMSEEKKPGTEHINLKVTGQDGSVVHFKIKKNTPLRKLMS AYCDRTGVKMEAMRFRFDGQPINETDTPSQLEMEDGDSIDVFQQQTGG---LPINPKPFL NGLTGKPVMVKLKWGMEYKGYLVSVDTYMNLQLANTEEYIDGALSGNLGEVLIRCNNVLY IRGVEEEDEEGEMKDMSDTEGD-IPS--VGTGAMDVNSALQEVLKTALIHDGLARGLHEC AKALDKRQAHLCILANNCDEPMYVKLVEALCAEHGINLMKVDDNKKLGEWAGLCKIDKEG KARKVVGCSCVVVKDYGKETQALDVLNEYFKSKR---VRKKLVVVGDGECGKTCLLIVFS KDEFPEVYVPTVFETYVADIEVDGVAVELALWDTAGQEDYDRLRPLSYPDTDVIVMCFAI DNPDSFENITEKWLPEVNHFCPNVPVVLVGTKKDLRGDPERIEDLSRRKLKPVVAEEAKV MADRIRAVGYMECSAKTREGVREIFEGAARASLQKSKRGKHRMDDYQTGEETAFVVDEVS SIIKEAVEGAIGGNSYQHNKVNQWTSTVVEQCLNQLTKLGKPFKYIVTCVIMQKNGAGLH TASSCFWDNTTDGSCTVRWENKTMYCIVSVFGLAIMFSASAKIVKPQGEKPDEFESSISQ ALLELEMNSDLKTQLRELFITAAKEIDVQGKKAIIIFVPVPQLRAYQKIQTRLVRELEKK FSGKHVVFIAQRRILPKPTRKTRRKNKQKRPRSRTLTAVHDAILEDLCHPAEIVGKRIRI KMDGSRLIKVHLDKNQQTTVEHKVETFSAVYKKLTGKDVVFEFPDYILGRGGFRGGFGGR GRGRGRGRGRGKE-DKEWIPVTKLGRLVKDLKIKSLEDIYLFSLPIKEFEIIDHFL-PSL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDYNGHVGLGVKCSKEVATAIRGAIVLAKLSV APVRRGYWGNKIGKPHTVPCKVTGKCGSVVVRLIPAPRGTGIVSAPVPKKLLAMAGIEDC YTSARGQTATLGNFAKATYAAIKMTYSYLTPDLWKETQFTKSPYQEHTDYLAKMSGGLDV LALKEEDVTKFLACGTHLGATNTDFQMEQYCYKRKADGTYIINLRKTWEKLLLAARAIAA IENPADVCVISARPYGQRAVLKFASATGATPIAGRFTPGTFTNQIQAAFREPRLLMVTDP RTDHQPVTEASYVNIPVIALCNTDSPLKFVDIAIPCNNKGAHSIGLLWWLLAREVLRLRG TISREVPWDVMVDLYFYRDPEEAEKESEVGDWASETVVAPVPIATEDWSATDTGDWSATP ATPDWGGMKFNKLVSSSRRKNRKRHFNAPSHIRRKIMSSALSKDLRQKHNVRSMPIRKDD EVQVVRGHYKGQQVGKVVQVYRKKFVIHIERIQREKANGASVHVGIHPSKVVIVKLKMDK DRKRILERKAKSRQVGKHTEESITSPSSTSVGSTVRQRKAPASGAGAAGMWRFYTEDSPG IKVGPVPVLVMSLLFIASVFMLHIWGKYTR-KKESRKKSSINDVVTREYTVNVHKRIHGI GFKRRAPRAIKEIKKFAEKMMGTPDVRVDTRLNKHVWSKGVRNVPYRVRVRLARKRNEDE DSPHKLYTLVTYVPVTTFKGTQTVNVDSSSKSEFLVNGKYRLVRKIGSGSFGDIYLGINI SNGEELAVKLESHKARHPQLLYESKLYKILQGGVGIPHIRWFGEKDYNVLVMDLLGPSLE DLFNFCSRRFTMKTVLMLADQMIGRIEYVHNKNFIHRDIKPDNFLMGIGRHCNKVFLIDF GLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRGS LPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGYPAEFAMYLNYCRGLRFEEAPDYMYLR QLFRILFRTLNHQYDYVFDWTILKQKAAPAMNPEKLKQRIGGKGSARRKKKIVHRTATTD DKKLQTSLKKLAVNNIPGIEEVNMIKEDGQVIHFNNPKVQASLAANTFAISGHAETKAIT EMLPGILNQLGAESLANLKKLATNPADIDEDDDEMPELVENFDEPSKGEMTRYSLDAENA TKSAKARGSHLRVHFKNTRETAQAIKRMHLRRAVRYLKNVVDKKECVPFRRYNGGVGRCA QAKNWGATQGRWPKKSAEFLLQLLKNAESNAEYKGLDTDHLIIEHIQ------------- ------------------------------------------------------------ ----------------------------------------------EMEKEGSGTIDFND FLTMMTQKMSEKDSKEEILKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQEADRD GDGEINETEFLRIMKKTSLY----RDKWHKRRATGGRQNPIRKKRKFELGRPAAHTKIGP KRIHTVRTRGGNKKYRALRLDTGNFAWGSEAQTRRTRIIDVVYNASNNELVRTKTLVKNA IVQVDATPYRQWYEGHYALPLGRKKGVKLSETEEAVLNKRSKKTQKKYDERKKLGKVEQA LEEQFSSGRLLACIASRPGQCGRCDGYILEGKELEFYLRKIKAKKGKMSLVVPEKFQHIL RVMNTNIDGRQKIAFALTAIKGVGRRYSHVVCRKADVDLTKRAGEMTEEEVDKLLTIMSN PRQYKIPDWFLNRQKDVKDGKYSQVMSNVLDNKMREDLERMKKIRAHRGLRHYWGLRVRG QHTKTTGRRGRTVGVSKKKASGTESDS-DSVPDLEDVAQAAGLPEELVSKAKQSRSEKKA RKAMSKLGLKQVAGVSRVTIRKSKNILFVINRPDVYKSPASDTYIVFGEAKIEDLSQQAQ VHAAKNFQREEEMDETGVEAKDIELVMSQANVSRPKAVRALKNNQNDIVNAIMMGRVRTK TVKKAARVIIEKYYTRLTNDFHTNKRICEEIAIIPSKKLRNKIAGFVTHLMKRIQRGPVR GISIKLQEEERERRDNYVPEISAIEEVDPDTKEMLKLLDFANIAGLQVTQPITSTMKWEY KEEHPFEKRRAEGEKIRKKYPDRVPVIVEKAPKARVGDLDKKKYLVPSDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGALYQEHHEEDFFLYIAYSDESVYGMRELRIMKL CLNICVGESGDRLTRAAKVLEQLTGQQPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAE EILERGLKVREYELRRNNFSSTGNFGFGIQEHIDLGIKYDPSIGIYGMDFYVVLGRPGFN VSKRKRKKGVIGHGHRATKEDAMKWFQTKYDGVILPGKMGIKFLEFVRPFCAVLPEIAKP ERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWIRVILASNRGTLMELGIS PIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMVITVGQAIVYVMTGMYGDPAE IGAGVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVN TGRGTEFEGAVIALFHLLATRQDKVRGLREAFYRQNLPNLMNLLATVFVFAVVIYFQGFR VDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAAKFSGNFFVNLLG AWADVGGGGPARSYPVGGLCYYLXPPETLHHVGEDPIHAVLYICFMLGSCAFFSKTWIEV SGSSAKDVAKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVMADFMGAIG SGTGILLAVTIIYQYFEIFVKEQSEMGGMSTLLFQTERAFQKQPTVFLNKKKVIIPRYVK NVGLGFKTPREAIEGNYIDKKCPFTGNVSIRGRILNGVVLKLKMQRTIVIRRDYLHYVRK YNRFEKRHKNMSVHLSPCFRDVAIGDVVTVGECRPLSKTVRFNVLKVTKGSGSKKGFSKF -VNVPKQRKTFCKGSKCRKHTLHKVTQYKKGRDSLYVQGKRRYDRKQSGYGGQTKPIFRK KAKTTKKITLKMECTECKFRKQLAIKRCKHFELGGDKKKKGQMIQFMGRVIRSQRKGPGS VFKAHTKNRKGAAKLRAVDFAERHGYIKGVIKDIIHDPGRGAPLAKVVFRDPYRYKLRTE TFVAAEGLYTGQFVYCGKKATLQIGNILPVGVMPEGTIVCCLEEKTGDRGRLARASGNYA TVISHNPENKRTRVKLPSGSKKVIPSTNRAMVGIVAGGGRVDKPMLKAGRAYHKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGHAST-XRDTSAGRKVGLIAARRTGRLRGSKSVIN KAKRTKKVGITGKYGTRYGASLRKTIKKMEITQHGKYTCSFCGKETMKRRAVGIWACGSC RKTVAGGAYVYSTTAAATVRSAVRRLRDMKEMGRRPARCYRYCKNKPYPKSRFCRGVPDA KIRIYDLGRKKARVDDFPLCVHLVSDEFEQLSSEALEAARICANKYLVKHVGKDAFHLRM RPHPFHVVRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQPIMSVRARENNKADVI ESLRRAKFKFPGRQKIYVSRKWGFTKWDREDYETMRRDGRLIPDGVTVQYLPDHGPLQAW KDRQKVTKILGRTGSQGQCTQVRVEFLDDSNRSIIRNVKGPVREGDILTLLESEREARRL R--KGTSSFGKRHNKTHITCRRCGGRSYHIQKKTCSRCGYPSTRMRKYNWSEKAKRRRTQ GVGRMAYLKVVFRRFRNGFREGTVAKPKRKMVDDRAAAKELDQWVEQLNECKQLTENQVK TLCEKAKEILTKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDR GYYSVETVSLLVALKVRFKDRITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHSNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRC GNQAAIMELDDALKYSFLQFDPAPRRGEPHVTRRTPDYFL-------------------- ------------------------------------------------------------ ---PTNQGVNSLKNQRSHQAIAEERVGRRCGGLRILSSYWVSQDSSYKFYEVVCVDPNHK GIRRDAKINWIVNPVHKHREMRGLTSSNRKSRGLGKGHKFNQTIGGSRHANWKKHN---- ----GIAIGRLSEERKAWRKDHPFGFVARPVKNADSTLNLMHWECAIPGKKTTPWEGGLF KLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSLLDEEKDWRPAVTIKQILLGIQE LLNEPNIKDPAQAEAYTIYCQNK-------------------GKSSKMLQHINYRMRCTL QDGRVFIGTFKAFDKHMNLILGDCDEFRKVKPKKAKEREEKRVLGLVLLRGENLVSMTVE GPPSADEGMARVPLPGSGGGPGMGRAAGRGIPGGGGLQGPVRGVGGPSSSMMQP--PMGR GGPPTDIPTFKLVLVGDGGVGKTTFVKRHLTGEFEKKYVATLGVEVHPLSFHTNRGQIKF NVWDTAGQEKFGGLRDGYYIQGQCAIIMFDVTSRITYKNVPNWHRDLVRVCENIPIVLCG NKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPA LAPPEVHMDPNMAQMYEKELEIAQQTALPEEDDDL------------------------- ------------------------------YVGEVVKPMDKKKVLVKVHPEGKFVVDLDK NIDINDVTANSRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYDMVGGLDKQIKEI KEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ KFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRLESGSGGDSEVQRTMLELLNQLD GFEPKQNIKVIMATNRIDILDSALLRPGRIDRKIEFPAPNEEARLDILKIHSRKMNLTRG INLRKIAEMMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFELAVAKIMQKDSEKNMSI KKQWKLGFAENFGLSGAAAVISKTAAAPIERVKLLVQNQDEMLKAGRLDKPYGGVVDCTV RTFKTEGFLPFWRGNLANCLRYFPTQALNFAFKDKIKLMFKMQKTDSYGVKFGKNIASGG AAGAMSLCFVYSLDYARTRLANDAKSGAKRQFNGLIDVYRKTLKSDGFVGLYRGFVISCV GIVVYRGCYFGFYDTLKPIVLGEDAGLMLSFALGYVVTISAGLVSYPIDTIRRRMMMTSG EAVKYKGSIDCTVQILKHEGFMSLMKGAGANILRGVAGAGVLAGFDKFKALYISWRL--- --------------EIIKESEVKSLCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLK ELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQV YGFYDECLRKYGSITVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRAIDRK QEVPHDGPMCDLLWSDPEETQGWGVSPRGAGYLFGSDVVAQFNAQNDIDLICRAHQLVME GYKWHFNDTVLTVWSAPNYCYRCGNVAAILELDEHLQRDFTIFEAAPQDSRGKPQADYFL VRLPPEVNRVLYVRNLPYKITAEEMYDIFGKYGAIRQIRMGNTPETKGTAFVVYEDIFDA KNACDHLSGFNVCNRYLVVLYYQSNKAFKKLDTEKKAQDLDKMKAKYGLSTPD--MSIGV PIKVLHEAEGHVVTCETKTGEVYRGKLVEAEDNMNCQMANITVTYRDGRVAQLENVYIRG SKIRFLILPDMLKNAPMFKKVGVGRGKSAILRAAARGRGGRGRGGDR------------- ------------INAKDHASIQLNLAEVDETTGRMTGGYKTYAVCGAIRRMGESDDCILR LAKRDNIVAKMPRGPRKHLKRLHAPKHWMLDKLGGVFAPRPSCGPHKLRECLPLMIFLRN RLKYALTYDECKKILNQRLIKVDGKVRTDNTYPAGFMDVISIERTGENFRLIYDVKGRFT VHRISNEEAGYKLCKVKRVGVGPKGVPLVVTHDGRTIRYPDPLIKVNDTVRLMGTKDDEY DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTA GQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADNNIVIMLVGNKSDL RHLRAVPTDEAKAFAEKNNLSFIETSALDSTNVETAFQNILTEIYRIVSQKQIRDSPDDG PVTTIKVAPTDNTAERKRPCCN-TARYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVR GKNLVVLGVEKKAVAKLQEDRTVRKIALLDDHVAMAFAGLTADARILINRARIECQSHKL TVEDPVTLEYITRYIATLKQRYTQSNGRRPFGLSALIIGFDGTPRLYQTDPSGTYHEWKA NAIGRSAKTVREFLEKYYTAEVASDQETIKLALKALLEVVQSGSKNMEIAIMKYNEPLKM MESEEVEKYIQEIEKEKEEEAEKKKQK--------------------------------- ------------------------------------------------------------ ----------------DDNHAIVSTSVGSEHYVSILSFVDKDSLEPGCSVLLNHKVHAVV GVLSDDTDPMVTVMKLEKAPQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIKPPK GVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPS IVFIDEIDAIGTKRYESNSGGEREIQRTMLELLNQLDGFDSKGDVKVVMATNRIETLDPA LIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTMSKDVNIDDYVLAKDDLSGADIKAICT EAGLLALRERRMKVTDDDFKKAKENVLYRKDEGTPEGLYLKRKPYSPFQNTGKADYALAR VDDLINWARKSSLWPLTFGLACCAVEMMHFAAPRYDMDRFGVVFRASPRQADCIIVAGTL TNKMAPALRKVYDQMPEPRWVISMGSCANGGGYYHYSYSVVRGCDRIIPVDIYVPGCPPT AEALLYSVLQLQKKIKRMKVVQRWYRKTDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYA NNSNYKNDTMIRKEAFVHKSVMEELKRVIEDSEVMQEDDTLWPPPDRVGRQELEIVIGDE HISFTTSKIGSLVDVNQSKDPEGLRTFYYLVQDLKCLVFSLIGLHFKIKPIMVAQKKVKK AIESINSRLALVMKSGKYVLGYKQTLKTLRMGKAKLVIIANNTPPLRKSEIEYYAMLAKT GVHHYNGNN--------------------------------------------------- ---------------------------------------------YSAMRDQYMRTGEGF LCVFAVNNTKSFEDINQYREQIKRVKDADEVPMVLVGNKVDLPTRSVETKTAKVLAESYA IPYIETSAKTRQGVDDAFYTLVREIRKFMGDRYNIHSQLEHLQSKYIGTGHADTSKWEWL TNQHRDSYASYMGHFDMLNCFAIVESEARARVRFNLMEKMLQPCGAPPERPEDMKVELCS FSGYKIYPGHGKKVVKSDGRAFQFINAKCEKSHLMKRNSRKINWTVLYRRKQKKGQQQEV AKKRTRRTTKFQRAITGATLNDIMAKRNQKPEVRKAQREQAIRAAKEKQKAKDMKAPRVG ---MKLNVAYPATGSQKLIDFEDDKKLRCFFDKRMAQEVSADSLGDEWKGYVVRISGGND KEGFPMKQGVMTNGRVKLLLSRGHTCYRPRRTGERKRKSVRGCIVDANLSVLNLVIVRKG EQEIPGLTDRTIPRRLGPKRASKIRKLFNLTKEDDVRQYVVRRPLPPATKAPKIQRLVTP LSLQRKRHRVALKKRRAAKKRDEAAEYAKLLAQRMKEAKERKMERRRSASQSKKVKAKEL RGKKKEDLLKQLDELKTELSALRVAKVTGGAASKLSKIRIVRKSIARVLTVISQTQKENL RKFYKPKDLRPKKTRAMRKALTKHERSIKTAKQQRKERLYPMRKYAVK---KGPKVTDKV FFDIAIGEEKIGRIIIGLFGKTVPKTVKNFKSLAEGFDTYKGSGFHRVIKDFMIQGGDFT KGDGTGGKSIYFADENFKLKHYGAGWLSMANAGKDTNGSQFFLTTKKTEWLDGRHVVFGK VLEGMDVVRNIEKTKTNRDKPESPVVIVDSGSLPVEEPFSVEKLPAKEKKKKTVLTFTID CTHPVEDGIMDSASFEKFLHERIKVSGKTNNLKSKLVITSDIPFSKRYLKYLTKKYLKKN NLRDWLRVVASTKDSYELRYFQINNEEEEEEED-------EEEKVYGGCEGPDAMYVKLV SSDGHEFIVKREHALTSGTIKAMLSGPGQFAENETNEINFREIPSHVLQKVCMYFTYKVR YTNSSTEIPEFPISPEIALELLMAANFLDC-KVVTAAELKQHNKGRDCWIAIHDKVYDVT KFLEEHPGGEEVLLEQAGSFATEAFEDVGHSTDARELMVQYEIGEI-------------- --------------MSYMLQHLHNGWQVDQAILSEEDRVVVIRFGHDWDPTCMVMDETLY KVAEKVKNFAVIYLVDITAVPDFNKMYELYDPCTVMFFYRNKHIMIDLGTGNNNKINWAM EDEHEFVDIVETVFRGARKGRGLVVSPKDYSTKYRYKKLQRQLEFLEVQEEYIKDEQKNL KKEYLHAQEEVKRIQSVPLVIGQFLEAVDQNTGIVGSTTGSNYYVRILSTIDRELLKPSA SVALHKHSNALVDVLPPEADSSITMLQSDEKPDVCYSDIGGMDIQKQEVREAVELPLTHF ELYKQIGIDPPRGVLMFGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVR DVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTVNVKVI MATNRHDTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPD KISGADINAITQEAGMQAVRENRYVVLAKDFEKGYKNNIKKDETEHEFYKSHAPLNLEMI KERVLLVLKLYDKINPEKLTLDSHFMNDLGLDSLDQVEVIMAMEDEFGFEIPDSDAERLM RPADIAQYIADKEDVSRRVQALADDLKNIEFETSEEVEVTPTFDSMGLREDLLRGIYAYG FEKPSAIQQRAIKPICRGRDVIAQAQSGTGKTATFSISILQCLDTQVRETQALCLSPTRE LAVQIQKVILALGDYMSVQCHSCIGGTNIGEDIRKLDYGQHVVSGTPGRVFDMIRRRNLR TRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVCLISATLPHEILEMTSKFMTDPI RILVKRDELTLEGIKQFFVAVEKEEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKM RDANFTVSSMHGDMPQKERDTIMKEFRSGASRVLITTDVWARGIDVQQVSLVINYDLPNN RELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLIVAMRRP FDPVAHELDAGFRLTKFADLKGGCKVPQEVLLKLLEGL-QG-DSEQAHFQYVAAVPRIGI GMDSCVTPLRHGGLSLVQTTDFFYPLVDDPYMMGKIACANVLSDLYAMGVTECDNMLMLL GVSQKLTDKERDVVVPLMLRGFKDLAEEAGTSVNGGQSVLNPWMTVGGVATTVCQPNEFI MPDNAVVGDVLVMTKPLGTQVAVNAYQWLDQSDRWNRIKLVVSEDDVRKAYQRAMFSMAR LNRTAARLMHKYNAHGATDITGFGMLGHANNLARIQKNEVGFVIHNLPIIAKMAAVSKAC GNMFGLLQGHSAETSGGLLIALPREQAAAFCKDIEKQEGYQAWIIGIVEKGNRTARIIDK PRVIEVPAKEKD--------VDGYFIHIDAHADECFFDKVSSGTKMSLMFEVAEGGFLDI DVKITAPDGRNIYSGDRESNGKYTFAAHMDGTYKYCFSNKMSTMTPKIVMFSMDIGEKPK ANHNKLEEMINELSTSLTGVKHEQEYMELRERIHRAINDNTNSRVVLWSFFEALVLVAMT LGQIYYLKRFFEVRRVVMAATLKPYLTAVRHTLTAAMCLENFSSQVVERHNKPEVEVRSS KELLLTPVMISRNEKEKVLIEGSVNSLRISIAVKQADEIEKILCHKFMRFMMMRAENFIV LRRKPVEGYDISFLITNFHTEAMYKHKLVDFIIHFMEEIDKEISEMKLAVNARARISAEE FL---SRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLV TMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTMPNTFKTLDSWRDEFLIQASPRDPEN FPFVVIGNKIDLENRAVSTKRAQSWCHTKGDIPYFETSAKEAINVEQAFQTVAKNALAQE TEVELYNEFPDQIKLTNEQNKEGCGCTSPFDSRFPNQNQTRNCWQNFVDYHRCHKVEDYE PCEYFKRVYNSLCPVEWTQQWTEQLETNSFAGKIMPDHLGSDQRKVKDDNKEDKPIQSLD EGDIALLKSYGAGMYSRSIKTTEDDIQNILKRVNELTGIKESDTGLAPPALWDLAADKQT LQSEQPLQVARCTKIINADSDDPKYIINVKQFAKFVVDLGDQVAPTDIEEGMRVGVDRNK YQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVEVPLLHPERFVNLGI EPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMART KKACIIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDT LDPALMRPGRLDRKVEFGLPDLEGRTHIFKIHARSMSVEKDIRYELLARLCPNSTGAEIR SVCTEAGMFAIRARRKMATEKDFLEAVNKVIKAYAKFSATPRYMTYN------------- ---------------------------------------SFKYAWVLDKLKAERERGITI DIALWKFETAKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKNGQT REHALLAYTLGVKQLIIGVNKMDSTEPPYSGARFDEIKKEVAAYVKKIGYNPDCVPFVPI SGWHGDNMLNMSWHKGWKVYTGSTLLDALDNIDPPTRPTNRPLRLPLQDVYKIGGIGTVP VGRVETGVLKPGVVVTFAPANVTTEVKSVEMHHTALEEALPGDNVGFNVKNVSVKDIRRG NVASDSKNDPAK------------------------------------------------ ----EDNPAHVKSGDAAIVNMVPQKAMCVE------------------------------ ---------------ELEQLRQEAEQLKNQIREARKAAADTTLTNAAASVEPVGRIQMRT RRTLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAP SGSYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDNQIVTSSGDMTCA LWDIETGQQTTSFTGHTGDVMSLSLSPDMKTFVSGACDASAKLWDIREGMCKQTFSGHES DINAITFFPNGFAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLG GYDDFNCNVWDTLKQDRAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKIWNMSYAYLF KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES FRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLEARR DVKKEEGEAFAREHGLIFMETSAKTAANVEEAFINTAKEIYQKIQDGVFDINNEANGIKI GPQHSPTSPTGGGGNKQGGAMTRGRTELGDVTVHNIKQLKRLNQVVFPVTYNDVFYKDVL EVGELAKLAYFNDIVVGAVCCREEKSNNQRRLYIMTLGCLAPYRRLGIGTVMLQHVLKIC EEDGNFDNVFLHVQVNNDGAINFYEKFGFEIVEQKQNYYKRIEPADAFVLQKTFRKMPKQ IMEIKDFLLTARRKDAKSVKIKKNVKFKVRCSRYLYTLVIQDREKAEKLKQSLPPGLSVK ELKMSKVSRDSLYEAVNAILAKKRKFTETVELQISLKNYDPQKDKRFSGTVKLNHIPRPK LRLCILGDQQHCDEAKANELANMDVEALKKLNKNKKLVKKLAKRYDAFLASDSLIKQIPK ILGPGLNKAGKFPTVLSHSESMTNKCDEVRATIKFQMKKVLCLAVAVGHVNMAPEELVSN INMSINFLVSLLKKNWQNVRSLYIKSTMGPAQRIYMAEIDKLNIDSIIARLLEVRGSRPG KNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLNTGRPVTPPRGNPKNK GKM--------------------------------------------------------- -------------------VMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPF ICTMPMRLDEGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDEL PAEFKLYLPVQ--MTDAQIQNFQDPFQDDHEIHIRIQQRNGRKTLTTVQGISVDYDLKKI VKACKKEFACNGTVVEHPEYGEVIQLQGDQRNNISGFLQKIGITNQLKVHGF--VYSFDG LLVFALLVICTCAYMKRV-PRLFLSEKKGLLGVFYKAAVIGTRLHIPVAL---------- ---SGRLVASLARQLPRTASQKNSVGAGFIATRKFNSTAEVSSILEERILGASKADLEET GRVLSIGDGIARVYGLKNIQAEEMVEFSSGLKGMALNLEPDNVGIVVFGNDKLIKQGDIV KRTGAIVDVPVGEGILGRVVDALGNAIDGKGPLKDTKRARVGTKAPGIIPRISVREPMQT GLKAVDSLVPIGRGQRELIIGDRQTGKTAVAIDTIINQKRFNDGADEKAKLYCIYVAIGQ KRSTVAQIVKRLTDADAMRYTIVVSATASDAAPLQYLAPYSGCTMGEYFRDNNKHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDAFGGGSLTALPIIE TQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTKAMKQVAG SMKLELAQYREVAAFAQFGSDLDAATQQLLNRGVRLTELLKQGQYMPMAIEEQVCVIYAG VRGLLDKIDPSKIVAFESEFLTHLRGTQQELLKGIREAGQITPENDAKLKDIVTTFLAGF MEALYRIPYSVLECPNIKIKKPSWLHMPSAMFVFAAVLLSYFMVTGGIIYDVIIEPPSIG STTDERGNSKPVAFMPYRVNGQYIMEGLASSFLFTMGGMGFIILDQTNKPTTPRLNRILL LCIAFVCILVSFFMCRVFMRMKLPMPKVKRSKKPPPDGWELIEPTVDELDQKMREAETDP HEGKRKVESLWPIFRLHHQKSRYIYDLFYRRKAISRELYEYCLKENIADKNLIAKWKKQG YENLCCLRCIQSRDTNFGTNCICRVPKAKLEEGKIVECVHCGCRGCSGEYAQVTKMLGNG RLEAMCFDGVKRLCHIRGKLRKKVWINSSDIILVGLRDYQDAKADVILKYTPDEARNLKA YGELPESAKINEDGDDIITFDDIDEILVRFLMKLSHETVTIELKNGTQVHGTITGVDVSM NTHLKTVKMTVKNKDPVQLDSLSIRGNNIRYFILPDSLPLDTLLIDDAPKAKARR--MQK PKSEMSPEELAQREQEEFNTGPLSVLTQSVKNNTQVLINCRNNKKLLGRVKAFDRHCNMV LENVKEMWTEVPKTGKGKKKSKPVNKDRYISKMFLRGDSVILVLRNPLPIIIDARGHLMG RLSSLVAKTILQGQRVVVVRCEGINISGSFYRNKLKYLDFLKKRMNTNPSRGPFHFRAPS KVFWRTVRGMLPHKLHRGKEAMDRLKVFEGIPPPYDKQKRMVVPSALKVLRVKPRRKFCV LGRLSHEVGWKYQNVIGTLEAKRKIKSRKFYERKKEELKLRQEAKKIAPYQAVIEGYGFA GDANKGKKVFVQRCAQCHTVEKGGKHKTGPNLNGLVGRKTGQAPGFSYTDSNKNKGITWG KDTLWVYLENPKKYIPGTKMVFAGLKKKTDRADLIAYLEDSTKIFVERTLAILKPDAVSE EIEDIILRSGFTILQKRRVHLTPEQASDFYAEHYGKLFFPSLVAYMSSGPVLTMVLARQK AITYWRELIGPTNTIKARQTHPDCLRAIYGTDDQRNGLHGSDSYASADREIRFFFPDSIV EPVPVGQAARDYLSKCVNPTLLKGLTEVCKQKPSDPVEWLADWLLENNPNKPKVAMFEAR LVQGSLLKKVLEAVKDLLNEATWDCSGNGMSLQAMDSSHVSLVSLLLRSDGFDTYRCDRN LSMGIKL----------------------------------------------------- -------------------------LSQIGESVVISCTKEGVKFSASGDLGTGNIKLAQT ANVDKEEEAVVIEMQEPVCLTFALQYLNFFTKATPLSPTVS------------------- ----------------KSLSAYHTSRPATAGRVVAVIGAVVDVQFDEELPPILNALEVKN RTPRLVLEVAQHLGENTVRTIAMDGTEGLVRGNECVDTGTPISIPVGPETLGRIINVIGE PIDERGPVNAKVFSGIHQEAPEFVEMSVEQEILETGIKVVDMLAPYCKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVISLKDDTSKVSLVYG QMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTQKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIA ELGIYPAVDPLDSTSRILDANIVGEQHYGIARGVQKILQDYKSLQDIIAILGMDDLSEED KLTVARARKIQKFLSQPFQVAEVFTGSAGKLVPLKDTIKGFQMILDGDLDHLPEVAFYMV GPIEEVVSKAERLAEE-MLMPKKNRVQIYENLFKEGVMVAKKDFHAAKHPEIEVPNLHVI KALQSLKSRGYVNEQFAWRHYYWYLTNEGIQYLRDFLHLPPEIVPATLKRQAMSQDRAEY RRGGASDKKADVGAGATMGKQNSKLKPEVLEDLRTSTEFSEHEIQEWYKGFLKDCPSGHL SVDEFKKIYGNFFPYGDASKFAEHVFRTFDTNGDGTIDFREFICALSVTSRGKLEQKLKW AFSMYDLDGNGYISRQEMLEIVTAIYKMV------------------------------- --------------------------SSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNL TGLNEQVPHYRQALDMILDLEPDDDLEDNPNQSDLIEQAAEMLYGLIHARYIMTNRGIAM MIE--------------------------------------------------------- ------------------------------------------------------------ MGNTKGYRRGTRYMFSRKFRTKGVIPLSTYLKKYQRGDIVDIKGNGAVQKGMPHKSYHGK TGRIYNVTPHAVGVIVNKRVGGRIIAKRINVRVEHIKHSNCRLDFLKRVEENERKKTEAN ERVHCKRIPAQPKEAHFVRTKFNKPVFLQPIPYEFIA-----YKQVSPADPDMSLRGTTD RAATSLFWLELFKGLGVTGSMIFKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAVCPAQAITIEAETRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEY STETHEELMYNKEKLLDNGDRWEPEIAANLQADHLYRMATPAKQSKPEGKNNHDADKEQQ EAIEQIDEVQNEIDRLNEQASEEILKVEQKYNKLRQPHFSKRSDLIAKIPNFWVTAFVNH PQVSALLIEEDEEALQYLTKVEVQEFEDIKSGYRINFHFDSNPYFENTVVSKEFHLNSSK STPINWKPGKDLVKKGRKRNHEEQESFFGWFTDHGDAGADELGEVIKDDIWPNPLQYYLA SEIEEEGGDEEGLDEEGKKLTKEEELLLQDFSRNVTTKSSALFYGNAFIVSAIPIWLFWR IHQMDPYILFGVMTLVTTYLVAFAYKNVKFLLKHKIAQKREEAVAREVMKKVADDKRMSK KEKDERILWKKNEVADYEATTFSIFYNNAMFLVLIVVLSFYILRSFSPTFNYMLSMGSAG GLLALFSTSTKATQGKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQT VCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVKELQRQ ASPNIVIALAGNKADLRMVEYDEAQAYAEENSLLFMETSAKTAMNVNDIFLAIAKKLPKN EPSVHLDQDSMAEYLASIFGTEKDKVNCSFYFKIGACRHGERCSRLHNKPTFSQTVLLQN LYINPQNTAQIMMSEMEVQEHYDDFFEEVYTELADKYGEIEEMNVCDNLGDHLVGNVYVK FRYEEDAEKAVADLNNRWFNGRPIHSELSPVTDFREACCRQYEMGECTRGGFCNFMHLKP ISRELRRQLYGRSRRSRSHSPPTRRSRSKSRRDRRKRSRSRERRR--------------- -----------------------------------------------------------G CAMSGLIADSRTMIDRARVEAQNHWFTYNERMTIESVTQAVSNLALAFGDDDADPGAMSR PFGVALLFGGIDEKGPQLYHMDPSGTFIQYDAKAIGSGSEGAQQALQEVYHKSMTLKEAC KHALTILKQVMEEKLNATNVEMALMTPTKLFHMCTKEELEEVIKDI-------------- ------------QQKDILTAKPWEKDPHYFKHIKISALALLKMVMHSRSGGNLEVMGLML GKVDGSTMIVMDAFALPVEGTETRVNAQAQAYEYMAQYTETAKQVGRLENAIGWYHSHPG YGCWLSGIDVSTQMLNQQFQEPFVAIVVDPVRTISAGKVNLGAFRTYPKGYKPPDEGPSE YQSIPLNKIEDFGVHCKQYYSLD------------------------------------- -----------------LGRGGFMEKKSEDKLAKATKDGCKNTIEAIHGLMSQVIKDKLF NQVGGLPRRIIKETQRLLTEPVPGIEATPDDGNARYFHVVVAGPKESPYEGGTFKLELFL PEEYPMSAPKVRFMTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPD DPLANDVAEQWKTNESNAIEIAKQWTRTYADNEQELLDYDE-EVQDAKDVKGTYVSIHSS GFRDFLLKPELLKAIVDCGFEHPSEVQHECIPQAILSMDVLCQAKSGMGKTAVFVLATLQ QLEPVDGQVSVLVLCHTRELAFQISKEYERFSKYMSTIKVAVFFGGMSIKKDEEVLKKNC PHIVVGTPGRILALSKTLNLKNIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMF SATLSKEIRPVCKKFMQD------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------PPSYGDLG KSARDLFSKGFNYGFYKLECKTKTNSGVEFTTNGNSNHDSGKVNGTLETKYKWKDYGLTF LEKWNTDNTLGTEITIEDQIAKGLKLSFDTQFAPQTGKKSGKIKSSYKREYVNGSCDVDF DFAGPTVHGAAVLGYNGWLAGYQMSFDKSKLQKSNFAVGYSTDDFTLHTNVNDGTEFGGS YYQRVNDELETGVQLSWTAGSNATRFGLAAKYTPDKESTFRAKINNSSQIGLSYQQKVRD GVTMTLSTLVEGKNFSQGGHKVGFGLDLEADTVREKALTDYRKKLLEHKELEARLKDMRE QLKELTKQYDKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQIDKSK LRAGTRVALDMTTLTIMRYLPREVDPLVYNMSIEDPGDIKYSMIGGLGEQIRELREVIEL PLKNPELFGRVGITPPKGCLLYGPPGTGKTLLARAVASQIETKFVKVVSSAMVD------ --LIREMFAYARDHQPCIIFMDEIDAIRRFSEGTSADREIQRTLMELLNQMDGFDALGQV KMIMATNRPDTLDPALLRPGRLDRKIEIPLPNEQARMEILKIHAAPIAKHGEIDWEAVVK LSDDFNGADLRNVCTEAGMFAIRAERDYVIEEDFMKAVRKVADNKKLESKLDYKPIMPES VVSVVSKFYDEYMNSTPKRLKIIDAYLVYMLLTGVVQFVYCCLVGTFPFNSFLSGFISCV GSFVLAVCLRIQVNPQNKGDFQGIGPERAFADFIFSHVILHLVVMNFIGSLSTPSQLLPL ELVDKCFGSRIHIIMKNEQEIVGTLLGFDDFVNMVLEDVTEFESTPEGRRVTRLDKILLN GNNITMLVPGGEGPEVIDHYENPRNVGSMDKDDTDVGTGLVGAPACGDVMKLQIKVDDDG RIVDAKFKTFGCGSAIASSSLATEWIKGKTLKEASTVKNTDIAKELSLPPVKLHCSMLAE DAIKAALSDYTLKKDMLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKES FDYLKTLASDVHVVRGDFDENLNYPEQKVVTVGQFRIGLNHGHQVVPWGDTESLAMVQRQ LDVDILISGHTHKFEAFEHENKFYINPGSATGAYSAQDSTVVPSFVLLDIQQSTVVAYVY QLIVDDVKVERIEYKKMGKFMKPGKVVLVLSGRYAGRKAIVVKNYDEGTTDKPYGHALVA GVDRYPRRVTKRMGKKKIKKRSKLTSFVKVCNFNHLMPTRYSVVALDKAIVNKDAFRDAA LRRKARREAKLKFEERYKTGKNRWFFTKLRFERTFIMVKPDGVHRGLVGEIMKRFEQKGF KLVAIKFQQATEDHLKKHYADLASRPFFNGLVKYMASGPVVPMVWEGEVVKTGRKMLGET NPFDSAPGTIRGDYCIEVGRNICHGSDSVESANKEIALWFDTSELVKWSPVADDWVYESE VPKPVKTPAKAKEKALRAKKSVLRGVRDKRQKKIRTSVHFRRPKTLKLARTPKYPRKSTP RRNRLDQFKIVKFPLTTESAMKKIEDNNTLVFIVDKRANKPMVKTAVKKLYDIDVSKVNV LIRPDGEKKAYVRLAPDYDALDIANKIGIIMPSKQMMRLRNEKHSKNITKKGDVPKTLKA SEEKYPVGPWMLALFIFVVCGSAVFQIIQSIQMXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- ------------------------------------------------------------ --------------------------------------------------EMFLAGEIRE TSQTKVLKQLLMLSSLEEDTIFGKIARGEIPTKFLYEDDQVVAFNDVNPQSPTHFLVIPR KPITQLSSDEQLLGHMMVVARKVAEQKDGYRLVLNDGKNGAQSVYHIHLHVFGGRQMGWP PMGGILSYFSGLFGSKERRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVTYKN LKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSMDRDRIGISKSELVSMLEEDELKKAI LVVFANKQDIEGAMTVTEVANALGLSSLKNRKYQIFKTSAIKGEGLDEAMEWLSNAIVNG K-------------------------------------NEFIPTPSGLGVHVNVLDPQFK TIMSRTYAAEGRFTFTSHTAGEHTICLHSNSTAWFGGGQLRVHLDIQVGEHANDYQQIAA KDKLTELQLRVRQLLDQVEQITKEQNYQRYREERFRQTSESTNQRVLWWSIAQTLILLVT GFWQMRHLKSFFEAKKLV----------------YFGPNLLNTVKQKLFTEVEGTCTGKY GFVIAVTTIDNIGTGYIQPSRGFVVYPVKYKAIVFRPFKGEVLDAVVTQVNKVGLFTEIG PLSCFISRHSIPADMEFDPNSNPPCYKTK------------------------------- ----------RLYCKAVFTGFKRGLRNQHENTALLKIEGVTNIKDTDYYLGKRCAYVYKC RVKTACPGHEKASRIRVIWGKVTRPHGNSGCVRAKFRKNLPPKAMGRRVRVMLYMAKKTY DLLFKLLLIGDSGVGKTCLLFRFSDDAFNTTFISTIGIDFKIKTVELGGKKIKLQIWDTA GQERFHTITTSYYRGAMGIMLVYDITNAKTFDNISKWLRNIDEHANEDVEKMILGNKCDM DDKRQVGKDRGDLIAKEHGIPFLETSAKSNINVEKAFMDLAQAILNKMPQNEHIELHRKR HGYRLDYHEKKRKKEGRKAHEMAQKAKKLRGIKAKLYNKQRHSEKIQMKKTLKMHEERKT RQKNNDEVPEGAVPAYLLDREGQTRAKVLSNMIKQKRKEKAGKWEVPLPKVKGVSEAEVF KVVKTGKTRRKAWKRMVTKVCYVGEGFTRKPPKYERFIRPMALRFKKAHVTHPELKATFC LPVIGVKKNPSSPMYTSLGVITKGTVIEVNISELGLVTQGGKVIWGKYAQVTNNPENDGC INAVLLVMAARPLISVYSEKGETSESNVTLPAVFRAPIRPDIVNFVHFQMRMNGRQPYAV SEKAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRR ININQRRYAMCSAIAATGIPALVMSKGHRVENLPEIPLVVSDKIQEYKKTKEAVQLLKRV KAWQDIEKVRNSKRFRAGKGKMRNRRRIQRRGPLIIYDKDNGIVRAFRNIPGINLLNIAN LNLLKIAPGGHVGRFCIWTESAFKKLDSLYGTWRVASKEKNGYNLPMTKMTNTDLSRLLK SDEIQKAVRAPKKDKSRRILKKNPLKNVRTMQRLNPYFAVQKRAALRKLHRQQLQDQRRG ISTTDAKGKARPRHTLKGSGEQELATKTLQIQSKRFYLDVKQNRRGRFIKIAEVGSGGKK SRLLLAMSTAAEFRDHLTEFSEHYASLGPPNPDNLPEDGKLKSEVMVKDNRRYYLDLKEN QRGRFLRVSPRSQQRSQIAIPAQGMIEFRDALTDLLDEFGPDDHEGQGELPEPRSMRVEN KMFYFDVGQNRRGVFMRISETNFRTAITIPEKSWARFRDVLADFVEKXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXX------------NMQHCNLLCLPENYQMKYYFYHG LSWPQLSYVAEDEKGKIVGYVLAKMEEDPEDSVPHGHITSLAVKRSHRRLGLAQKLMDQA SRAMVECFKAKYVSLHVRKSNRAALHLYQNTLKFQTSEIEPKYYADGEDAYAMRRDLTPL AEQ-MSHTILLVQPGKKPEGRTYSDYESMNEALEGVCKIYEEYLKRSNPNVPSITYDISQ LFDFIDKLSDLSCLVYQKTSSTYVPHDKEWIKEKIYTLLRNQAG-MTEPSEEKKTEETKR VVHTYPLIRHSDMNEEMRTEAMELCVTACEKFSTNNEVAAKMIKETMDKKFGASWHAVVG EGFGFEITHEVKNLLYMFFGGNMAIMIWKCSMSHRKFSAPRHGSLGFLPKKRSRRHRGKC KAFPKDDRNKPCHLTAFLGYKAGMTHIVRDVDRPGSKVNKKEIVEAVTIVETPPMVVVGV VGYIETPTGLRTFKTIFASHLSEECRRRFYKNWYKSKKKAFTKYSKKWQDEAGKKEIEKD FQKMKKYCKVIRIIAHTQMKLLKKRQKKAHIMEIQVNGGTIPEKVDWAREHMEKQIPIES VFAQDEMIDVIGVTKGKGYKGVTSRWHTKKLPRKTHKGLRKVACIGAWHPSRVGFSVARA GQKGFHHRTEINKKIYRMGKGIHTEGGKVIKNNASTEYDITEKTITPMGGFPHYGEVNND FIMLLGCTVGPKKRVLALRKSLLVHTKRRALEKINLKFIDTASKFGHGRFQTHQEKQSFM GPLKKD------------------------------------------------------ -------------RPLSYPQTDVFLICFSLISPASFENVRAKWYPEVSHHCPNTPIILVG TKLDLREDKETVEKLREKKLCPITYPQGLAMAKEIGAVKYLECSALTQKGLKTVFDEAIR AVLCPKPKPKKKKPCALLIFDPTLKKKKKKKTPFDLDAAQDDIIMDDSMSKKKKKKKKPF DLAELDEALPKSEDSLPSKKKKEDSDRDYTYDELLKRVFDIMREKNPDMVAGEKKRFVMK PPQVMRVGTKKSSFSNFAEICKMLHRQPKHLLAFLLAELGTSGSVDGNNQLIIKGRFQQK QIEAVLRRYIKEYVTCHTCRSPDTILQKDTRLFFLQCETCGSRCSVASIKSGFQAVTGKR AAIRAKTT--------------------------------LEWPSLTAQWLPDVTRPEGK DYSLHRLILGTHTSDEQNHLLIASVQLPNDNAQFDASHYDSEKGEFGGFGSVSGKIEIEI KINHE------------------------------------------------------- ----------------------------NATPKEGRVIDAQTIFTGHTSVVEDVSWHLLH ESLFGSVADDQKLMIWDTRSTNTSKPSHTVDAHTAEVNCLSFNPYSEFILAT-------- ----------LHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQSAEDA EDGPPELLFIHGGHTAKIS----------------------------------------- ---MPAPSRARVYADVNTHRPREYWDYESHVVEWGQQDDYQIVRKLGRGKYSEVFEAVNI TNNEKCVIKILKPVKKKKIKREIKILENLRGGTNIITLLAIVKDPVSRTPALIFEHVNNT DFKQLYQTLTDYDIRFYVFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLA EFYHPGQEYNVRV----------------------------------------------- ------------------------------------------------------------ -------------------------------AVPESLLKKRKQNADKLRQKRRVMFTRAE KYVREYRKTEAEEIRLARQARKHNNFYVPADAKVAFVMRIRGINGVHPRPRKVLQLFRLR QINNGTFVKLNKATRQMLRIAEPYICWGYPNLKSVKELIYKRGYGKIDGRRIPLTDNALI EKKLGKCGIICVEDLIHEIFTVGPHFKEANNFLWHFKLNTPNGGWRKKNNHFVDGGDFGN REDKINNLLKKMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSKAHPPELKKYM DKRLSLKLNGARTVVGILRGFDPFMNLVVDEAIEECKTGEKHSIGMVVVRGNSIILLEAL DRIEFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTI RLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFQ-------------------- ------------------------------------------------------------ -----------------MAIKYNMAVGLDKGHKVTVQRPRPSRRKGVLNKHVKFIRDLIR EVTGFAPYERRTLELLRISKDKRALKFCKKRLGTHLRGKRKREEMIRTIQQQRKAXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFLDGLDFLDDVRRMNARQLYYQ VLNFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFYRGDLLFLTNYREEPIRVGE IVVFKVEGREIPIVHRVLKVHEKEDGAVKFLTKGDNNQVDDRGLYAPGQSWLEKKDVVGR ARGFVPYVGIVTILMNDYPKFKYAILALLGLFVLIHREMTTMNPEYDYLFKLLLIGDSGV GKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYR GAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEY ADQLGIPFLETSAKNATNVEQAFMTMAAEIKNRMGPAPSPSNVKINASTPVKPSGGGCCE ESLGEEVLRMSTDEIVSRTRLLDNEIKIMKSEVMRISHELQNQKEKIKENAEKIKVNKTL PYLVSNVIELLDVDPQDQGEEDGANVDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDPEQL HPGDLVGVNKDSYLILETLPQEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELIEAVVLP MTHKERFESLGIEPPKGVLLYGPPGTGKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGA KLVRDAFALAKEKAPAIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNSN IKVIAATNRVDILDPALLRSGRLDRKIEFPTPNEEARARILQIHSRKMNVSNDVNYEELA RCTDDFNGAQCKAVCVEAGMIALRRGATELTHEDYMDAILEVQAKKKTNLNYYAKDAADQ NFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRQDKRVKLQIWD TAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDNAQVVLVGNKC DLEDERVVSTDRGKQLADQLGLEFFETSAKENINVKAVFERLVDIICDKMSESLDSDPTH TKRLTENPNPQNAGCQC------------------------------------------- ------------------------------------------------------------ VFNGSGKPVDKGPPVLAEDYLDIQGQPINPWSRIYPEEMIQTGISAIDGMNSIARGQKIP IFSAAGLPHNEIAAQICRQAGLVKLPGKSVMDDHEDNFAIVFAAMGVNMETARFFKQDFE ENGSMENVCLFLNLANDPTIERIITPRIALTTAEFLAYQCEKHVLVILTDMSSYA-LFSQ VSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLT GYITEGQIYVERQLHNRQIYPPINVLPSLSRLMKSAIGEGMTREDHSDVSNQLYACYAIG KDVQAMKAVVGEEALTPDDLLYLEFLQKFEKNFIAQGHYENRTIFETLDIGWQLLRIFPK EMLKRIPQDKLAKYYPRDA--------------NNMLYPKEDKENRVLLYACRNCDYQQE ADNPCIYVNKIEHDIDELTQIIADVIADP-------------------------RRAEEG MRLYYVCTLPSCAHRWTEKPPFKVADISLAEWGRKAIEIAENEMPGLMELRKKFGTSKPL KGARIAGCLHMTVQTAVLIETLLELGAEVQWSSCNIFSTQDHAAAAMAKRGVAVYAWKGE TDEEYIWCIEQTLVFPDGKPLNMILDDGGDLTNLVHEKHSDYLKDIKGLSEETTTGVHNL YKMVQKGELKCPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGKVAVVAGYGDV GKGCARALRAFGSRVILTEIDPINALQAAMEGYEVTTMEEACKVGRIFVTSTGCKEIINA SHFEQMQEDSIVCNIGHFDCELDVKWLNENCTKKDTIKPQVERYTLKNGRHIILLAEGRL VNLGCAMGHPSFVMSNSFANQVLAQIELWTKADKYSLGVHILPKELDEEVARTHLDHLGV KLTKLTEGQASYLGIPVQGPFKPEHYRYADEQEQPPANTVEEPLDLIRLSLDERIYVKMR NERELRGRLHAYDQHLNMILGDVEETVTTVEIDEETYEEIYKSTKRNIPMLFVRGDGVIL VSPPM--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFKSLLDSARNSPF GSPFGLKVNENRSISAAQDETSCEFGSTKYFALCGFGGILSCGITHTAVVPLDLVKCRIQ VDPGKYGNIINGFRVSVRESGIRELAKGWAPTFFGYSAQGLCKFGFYEVFKSVYANILGE ENTYLWRTSLYLAASASAEFFADIALCPMEAVKVRIQTQPGFANTLREGFPKIYQQEGAW GFYKGIVPLWGRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKAEQLVVTFVAGYIAG VFCAIVSHPADTIVSKLNQDSGSSVGEVAKKLGFMGMWKGLFPRIIMIGTLTALQWFIYD SVKVYFKLPRPPPPEMPESLKRKLEHWKKERIVAIALLPIIPTALMFALDTTLTAMVMHS HWRLSGVAEDYIHLSICAFGSLCYLNFYDVGFANAVRTLYTQL-------SSDLTFPTEF ENAETLLISEVQRKQQNESAEDEQELSEVFMKTLNYTQRFSKFKNRETIAAVRSLLMQKK LHKFELAALANLCPENADEAKALIPSLEGRFEDDELQQVLDDIQTKRSFQY--------- ------------------------------------------------------------ -----ANAKIYKCDDESVPRPQCYTSRGSAHPDEFPCDLPGAGKYKLIRHVSFVDCPGHD ILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQ AQEQYEQILRFVQGTIAEGAPVIPISAQLKYNIDAVCEYITKKIPTPLRDFTSEPRLIVI RSFDVNKPGCEVDDLKGGVAGGSILRGVLKVGQEIEVRPGIVAKDQEGKLTCKPIFSRIV SLFAEQNDLQYAVPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPDIYTELEISYFLLR RLLGVRTEGDKKGAKVQKLSKNEILMVNIGSLSSGGRVLAVKADLAKIGLTSPVCTEIGE KIALSRRVEKHWRLIGWGQIRRGLTVKP-------------------------------- -----------------------------------------------------FMKNPMT DPSMMTDMMKGNLTNVLPMIVIGGWINWAFSGFLTTKVPFPLTLRFKPMLQRGIELQSLD ASWVSSASWYFLNVFGLRSMYNLILGQDNAADQTKVMQDQMSGAAMAMPPDPSKAFKAEW EALEIAEHHWALEGVEDEI-MFLWDWFAGVLNFLGLYKKSGKLVFLGLDNAGKTTLLHML KDDRMAQHVPTLHPTSEELSMGGMKFTTFDLGGHQQARRVWKDYFPAVDGIVFMVDAFDR ERYVEAKAELDSLLTDEQIANAPVLILGNKIDIPGAASEDELRHVFGLHGQTTGKGTIAR SELRPMELFMCSVLKRQGYGEGFRWLAQYIN----------------WPDESFEEMDSTL AVQQFIQQGIRRDYNNIDEILNPPDGQDEGVWKYEHLRQFCMELNGLAVKLQMECNPDTC TQMTATEQWIFLCAAHKTPKECPAIDYTRHTLDG-------------------------- ---------------------------------------------------------MPN IKLQSSDGEIFEVDVEIAKQSVTIKTMLEDDEDEEEAVPLPNVNAAILKKVIQWCTYHKD DPPPPEDDENKEKRTDDISSWDAEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMI KGKTPEEIRKTFNIKNDFTPAEEEQVRKENEWCEEKXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---SAVYI LDVKGKVLICRNYRGDIDMSVVDKFMPLLMETEEEGIVGPIIQHGTVAFVYIKYNNLYLV ATTKKNSNIAMVFSFLHKIVQVFCEYFKELEEESIRDNFVIIYELLDELMDFGYPQTTDS KILQEYITQEGHKLEIAPRPPMAVTNAVSWRSE--------------------------- ------------------------------------GKSKSVELEDVKFHQCVRLSRFEN DRTISFIPPDGEFELMSYRLNTHVKPLIWVESVIERHAHSRVEYMIKAKSQFKRRSTANN VEILIPVPMDADSPKFKTTTGSC------------------------------------- -----PVALDFEISGFVCSNLQIRFLRVFDRESYVPMRWVRYVTVTDSY----------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------KKGGG ISFNATSILTKVNEKLVQMILHEYKIFNAEVLFREDCSADDFIDVILGNRVHLPCLYVYN KIDQISIEEVDRIAREPDSVVVSCNMKLNLDYLLEKIWEYLALVRVYTKKRGERPDFEGG LILRSG-CTVEHVCHTVHRTLAANFKYALVWGQSAKYSPQRVGLAHQTTHDDVVQIVKK- ---------------------------------------------DECNYGSYQGRCVIC GGPGVSDAYYCKECTIMEKDRDGCPKIVNLGSAKTDLFYERKKYGFKKRPNLPPISADKI SGRSELRKIPVPANRYTPLKENWLKIFTPIVEHLHLQVRFNLKTRNVEIKTCKATNDIGA LQKAADFVKAFTLGFEVEDALALVRLDDLFLESFEITDVKPLKGDHLSRAIGRVAGKGGK TKFTIENVTKTRIVLAETKIHIMGSFQNIKIARTALCSLILGSPPSKVYGNMRAVASRSA ERRIEVANPVVELDGDEMTRIIWANIKEKLIFPYVNVECLYYDLGLPYRDATDDQVTIDA AHAIQKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPIICKTIPRL VPGWTQSIVIGRHAFGDQYKATDFVAKGSGKFELVYTPSGGGEQRFEVFNFKD-GGVGMG MYNTDESIKGFAHSCLQYALKKKWPLYMSTKNTILKRYDGRFKDIFEEIYESTYKKDYEA AGIWYEHRLIDDMVAQALKSNGGFVWGCKNYDGDVQSDV--------------------- ------------------------------------------------------------ ---------------------------------------------XXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------IKVLNDFLADK SYIEGYVPSQADSVVFSALPNPSSKFAHALRWYNHINSYGNERNSFPGPKKSADSFGPVD ADNKDDDDDFDLFGSAAEKLKQERLAAYEAKKSTAIIAKSSIILDVKPWDDETDMAALEE KVRSVTMDGLLWGASKLVPVGYGIKKLQICCVIEDDKVSTDDLEDQIVGFEDYVQSMDIA AFNKI------------------------------------------------------- ------------------------------------------------------------ --------REETEIIEGEVVEIQIDRPATGTGAKVGKLTLKTTEMETIYDLGQKMIESLT KEKV-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------EFLTKNYDFRPDMIDTLYRFAKFQYECGNYSGAAEY LYFVRVLVPANDKNALAALWGKLASEILMQDWDTALDDLNRLKEVIDQPLQSLQQRTWLI HWSLFVFFNHPKGRDLIIDMFLYTPQYLNAIQTMCPHILRYLTTAVITNKTVLKDLVKVI QQESYTYRDPITEFLECLYVNFDFNGAQQKLRDCETVLTNDFFLVACLDDFIENARLFIF ETFCRIHQCLTISMLAEKLNMNPDEAEKWIVNLIRNARLDAKIDSQLGHVVMGTQAVSPY QQVIEKTKGLAFKSQMLVMNIEKKLGAKAMGLELETISPGDGCTFPKSGQTVVVHYTGVL EDGKKFDSSRDRNKPFSFKIGKNEVIKGWDEGLKQMSLGQRARLKCPSTMAYGKRGFPGV IPPDSTLIFDIELL---MPKYYCDYCDTYLTHDSPSVRKTHCNGRKHKENVRVYYQKWLE EQVQKLVDDTTAAFKAGSGKSGSSST----PAAPASA-SVPPGP-----APGPG------ -----------------EPLTLERDVQRAVELLDHLQKSGELSKLSSLQKVLQSEFFSAV REVYEHVYETVDISGSPEIRANATAKATVAAFAASEGHAHPRVVELPKTEEGLGFNVMGG KEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGVSVEGEPHEKAVDLLKAAQGMAKLV VRYT---------------------LACLVGLALSDPVVYLQEDFWEDRWVLSEHKGGEQ GVFKISAGKFYGDAEKDKGLQTTQDARFYGASAKFDESFSNEGKSLVIQFTVKHEQNIDC GGGYVKLFPADMDQKDMHGESPYYIMFGPDICGPGTKKVHVIFNYKGKNLLTKKDIRCKD DVFSHLYTLIVRSDNTYEVKIDNKKVESGDLESDWDFLAPKKIKDPEAKKPDDWDDREKI DDPEDSKPEDWDQPEHIPDPDAKKPDDWDDEMDGEWEPPMIDNPEYKGEWKPRQVDNPSY KGKWVHPEIDNPEYSADDNLHSYSNIGALGFDLWQVKSGTIFDNVLITDDEAHAETVGEE TWGKTKDSEKKMKDEQDEEERKQREEEEKKRKEEEGDKEEDDEE------EPSLYTVKAI LILDNDGNRLISKYYDDTFPSVKEQKNLFNKTHRANAEIIMLEGLTCVYRSNVDLFFYVV GSAQENELILVSVLNCFYDAISQMLRKNVEKRALMDNMDGAFLALDEICDNGIILESDPS AIASRVAFRSDDIPLGEQTVAQVLQSAK-------------------------------- ------------------------------------------------------------ ATYDSNHDTFRMEFLIVPVAGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGE AETITSHYLFALGSYRALYIFNWIYRYYFEGFFDLIAVVAGCVQTVLYCDFFYLYITKVW KGKKLTLPA--------------------------------------------------- ------------------------------------------------------------ -----------------------------------MGGYGKTVSHVIIGLKTAKGTKQLK LDPSIYESLQKEKVETGDVIYIEANSGAVKRQGRSDTFATEFDLEAEEYVPLPKGDVHKK KEVIQDVTLHDLDIANARPQGGQDIMSMMGQLMKPKKTEITDKLRKEINKVVNKYIDQGI AELVPGVLFIDEVHMLDIECFTYLHRALESTIAPIVIFATNRGKCTIRGTEDLVSPHGIP LDLLDRLMIIRTLPYSQEEMVQILKIRAQTEDIEVTDESSQLLGEIGVKTTLRYAVQLLT PASLLSKINGKDAITREEIEEINELFYDAKSSAKILAEQKDKYMQDFEVDEEGDQGLQKL KEKVKRRKGRGF-THTGVDEYEAMEVGGPGPQRSVEGWILFITNVHEEATEEDIMDKFGE FGEMKNLHLNLDRRTGFLKGYALVEYETFSEAQAAMENLNGSEILEQKISVDWAFVRGPQ GKKMSYQLYRNTTLGHTLQESLDELIQCGQINPQLALKVLFQFDKAINTALATRVKNRIT FKGHLNTYRFCDNVWTFVLD-------------------TFLFTSESVGEGHPDKICDQI SDAVLDAHLKQDPTAKVACESASKTGMIMLLGEISSKAHVDYQKVVRDTIKYIGYDDSAK GFDYKTCNVLSALEEQSPDIAQGVHVGRDEDDIGAGDQGLMFGYATDETEECMPLTVILA HKLNAKMAELRRNGGLPWARPDSKTQVTIEYKLDNGACVPLRVHTVVISVQHSEEVTLEQ LRKDLMDKVVHAVIPDKYLDEKTIYHLQPSGRFVIGGPQSDAGLTGRKIIVDTYGGWGAH GGGAFSGKDFSKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVAKPLSVFVSSYGT GVRHDRDLLAIVEENFDLRPGRIVKDLDLRRPIYQRTAAYGHFGRPEFSWEQAKVLKM-- ---------------------------NEENFFEWEAYITGPEGTCFEGGVFPARLTFPS DYPLSPPKMKFTCDIFHPNIYPDGRVCISILHAPGDDPMGYESSAERWS----------- -------------------------------------------MRLEKCYFCSSTVYPGH GIQFVRNDCKVFKFCRSKCHKAFKKKRNPRKVKWTKAFRKSAGKDLAVDPALEFEKRRHV PVKYKRELWNKTVNAMKRIEEIKVKRQNRYIINRLKKGKELRKEADIKEVEKNIHLIRAP AAR---YKVVMIRHGESQWNKENRFCGWFDADLAESGIEEAKNAGKMLKEKGYVFDIAFT SVLKRAIKTLYFVQDELDLHWIPVVRHWRLNERMYGALQGLNKAETAAKHGEDQVKIWRR SYDTPPPAVEISDERWPGHDPKYQFVDRQLIPKAECLKDTVGRALPFWYDFIVPEIKRGQ RVVIAAHGNSLRAMVKYLDNMSDEEIMATNIPTGIPLVYELDEELRPIKHYYLASEEQVK AAMDKVAAQGKAK----------------------------------------------- -----------------------------------FPLHIGDHVFVGDDSIINAAQVGSY VHIGKNCIIGRRCVLKDCCAIADNTVLPPETVVPPFTYFSGSPGMSFLFGSRSNKTFKPK KNIPEGTHQYDLMKHAAATLGSGNLRLAVTLPEGEDLNEWVAVNTVDFFNQINMLYGTVT EFCTQESCPVMSAGPKYEYHWADGQTVKKPIKCSAPKYIDYLMTWVQDQLDDESLFPSKI GVPFPKNFLSIAKTILKRLFRVYAHIYHQHFQQVIQLQEEAHLNTSFKHFIFFIQEFNLV DRRELQPLAEL--------MGIDICHKHDRKVRRTEPKSQDIYLRLLVKLYRFLARRTDA KFNKIILRRLFMSKSNRPPMSIARLVRFMKKPGRDGKTAVVVGTITDDLRMLELPKLKIC ALHVTDRARARILKAGGQIITFDQLALKAPKGQNTILMQGARKAREANRHFGRAPGVPHS HTKPYVRSKGRKFERARGRRKSRGYKN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------NLLKAAKYHSVPFIVCAAMFKLSPQYMCSYDDAFNKFVSPQDI YNPVFDYVPPDLVTLYIS-------------------MIVPIRCFTCGKVIGNKWEAYLG LLQAEYTEGDALDALGLKRYCCRRMLLAHVDLIEKLLNYAPLEK---------------- -------------------TDSFLDRPPSPLFIPAKTGVDIATQILEGELFDFDVEVRPV LEVLVGKTVEQSLLEVMEEEELANLRSQQRAFEELRNAELVEQQRLEEQERRHRQEKERR MKQQREIMRKEKETADKIAARAFAQSYLADLVPSVFGTLSDNGYFYDPVERDVEQGFLPW LMDQVETQLDQVVLSRTVLDGLIREVVSQRGDAFQQMKARGELKEYKIIGRALPTEKNRV PKLYQMRIFAPEKVTARSRFWYFCGLLRKMKKSHGEIVLCQRIYEKYPLKIKNIGIWLRY VSRSGIHNMYREYRDLTITGAVTQCYRDMGARHRARSSSIQIMRVEVVPASKCRRANIKQ FHETTIRFPLPHRVSKRLHYPRFTTKRPNTCFSATDQMQEFWDKNQKRPNSPWTIYRWHM PMLTSFTHRITGISMGVALYTLSIGLFVAPGDFPSYVQMIQSWELSPLILFPLKFVAAFP LIYHYINGIRHLGWDFKGGYELATQVKTGSVIAASFSYW--------------------- -------------------------ELFSRCGDVKRVIMGLDKYKKTPCGFCFVEYYSRE DAENSMRYVNGTRLDDRIVRTDWDAGFVEGRQYGRGKTGGQVRDEYRNDYDSGRGGYSKI VSQKLKPNYSLKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGH KLGISDVAWSTDSRLLVSASDDKTLKIWELASGKCLKTLKGHSNYVFCCNFNPQSNLIVS GSFDESVRTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG KWIVSGSEDNMVYIWNLQTKEIVQKLAGHTDVVLTCACHPTENIIASAALENDKTIKLWR SDVMIIYKDIISDDEFFSDTYPDVVYEVTGKGDVDIGANPSSGVNIVLAKKKEYQIHIKE FMKKIKEYQFFLGVALMKWATPKMYFFKHALNAEKVMAVEFDQGVVFGADSRTTTGSYVA NRVTDKLTRVTDYIYCCRSGSAADTQAIADIVTYHLGFHKMQMDEEPRVKTAATVFQDLC YSYRDQLSAGIICAGWDKRLGGQVYSIPLGGMCVRQPFAIG------------------- -----------ALSLAISRDGSSGGIARLAAITADGVERKTILHNDLPKF---------- ----------------------------------------------PDLEELEVNMEDNE DAESTKSEVKLGKLQFSMDYDFQKGELSIGVIQAADLPGMDMSGTSDPYVKVYLMPDKKK KFETKVHRKTLNPVFNETFTFKVPYAEMGSKTLTFAIYDFDRFSKHDQIGQVLVPMNSID LGRVVEEWRDLTSPESDNEKENKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSD P------------------------------------------QKVTQIITVVDYDRIGT SEPIGRVVLGCNSTGTELRHWSDMLANPRRPIAQWHTLQEMPEKN--------------- ------------------------------------------------------------ ----------LIDPGVKAWTPTKARNNIIMFVGLQGSGKTTTCTKLAYYYQKKGWKTCLV CADTFRAGAFDQIKQNATKARIPFYGVDTSGRHKQEDSLFEEMLQVSNANPDNIVFVMDA SIGQACEAQARAFKDKVDVASVIITKLDGHAKGGGALSAVTHSPVIFIGTGEHIDDFEPF KVQPFVSKLLGMGDIEGLIDKVNELKLEDEELLNKLKH---------------GQFTLRD MYEQFQNIMMSIMSYNGAAIVAMKGKNCVAIASDRRYGVQAQTVGMDFQKIFEMGPRLYM GLPGLATDVQTVAQRLKFRLNLYELRENRSIKPKTFMSVVSNLLYERRFGPYFVEPVIAG LDQKTLEPFVASMDLIGCPMVTDDFVVGGTCTEQLYGMCESLFKEDMEPDQLFECVSQCL LNAVDRDAVSGWGAVVHIIEKDKVTTRTLKARMDMTSKDYYFDSYAHFGIHEEMLKDEVR TLTYRNAIYHNKHLFKGKVVLDVGCGTGILSMFAAKAGARKVIGVECSSIVEYAEKIVKA NNMDHVVTLVKGKVEEVKLPEGLEKVDIIISEWMGYCLFYESMLNTVLYARDKWLAEGGL IFPDRATLYVCAIEDRQYKDEKINWWDSVYGFDMSCIRKVAISEPLVDVVDPKQVVTNSC LVKEVDIYTVKEEDLTFTAPFHLQCRRNDYIQALVTFFNIEFTACHKRTGFSTAPESRYT HWKQVNESLTVKNGEEIYGVMNIKPNKKNARDLDFVI--------------------MVK EDKTTWKSNYFLKIIQLLDEFPKCFVVGIDNVGSNQMQKIRISLRVLMGKNTMMRKAIRG HLENNPSLEKLLPHIKGNVGFVFTKSDLSEVRDLISENKVAAPAKAGAIAPVDVKIPAQN TGLGPEKTSFFQALSIPTKIARGTIEILNEVHLVKIGDKVGASEATLLNMLKISPFSYGL IIQQVFDSGTVFAPGVLDITDDDIRARFMQGVSNIAAVSLAIGYPTVASVPHSVINGFKN LLAIAAATEISFKEAETLKE---------------------------------------- ----------------ARNDIAIVLINQNIAEMIRHALDAHTEPIPTVLEIPSKDHPYDA SKDSILRRAKGMFSAEDLR------------------------------------ICLED FKKALNLKRSFFAERFFSLFDQDGSGTIELPELLEGLHMLT-KGDRRQKLKF-------- ------------------------------------------------------------ --------MTYVTTWEEFAKAAEKVYTTDPTKCRFVIKYRHCDGQLCVKVTDDQVCVQYR TEHAQDVKKLEKLTSQLMRHMASKD----------------------------------- ----------EYTASCSKLLVQYKAAFKQVENEEYPSVEVFVKKSKLDCPAALERIREDR PITIKDDKGNTSKCIADIVSLFITIMDKLRLEIRAMDEIHPDMRELMETMNRLSILPADF EGKLKVNGWLQTLGGMQASDELTDAQVRQMLFDLESAYNAFNRVLHNMLSRMVKDHQTKQ QARKEIQEKRKKEAAAATALTHALVDHLNAGVAQAYVNQKKLDTETKILQANATQFSKQT MQWLKLVEDFNQSLKEIGDVENWARSIETDMRTVSSALEYAYKGRVVEKQIGGEKNGGKR MVRINRLPRFYPTEDRPKKLLSRFDDHKHKLRSTITPGTVLILLAGRHKGKRVVFLKQLS SGLLLVTGPFHLNGCPLRRINQIYVIATKAKVNIDEVKVPDNVNDEYFRRKKLRKPKHAE GDIFDTKKEEYAVTEERKKDQQEVDSQVLAAVRKHAEKKLMFGYLGATFSLKNRVYPHTL VFLEWLFGRKKTPQEMLRQNQRALNKAMRDLDRERQKMEQQEKKVIADIKKMAKQGQMDA VKIMAKDLVRTRRYVKKFILMRANIQAVALKIQTLKSNDAMAQAMKGVTKAMSTMNKQLK LPQIQQIMMEFEKQSEIMDMKEEMMSDAIDDAMGDEEDEEESEAVVQQVLDELGLQMADE LSDLPGTGKSAPKQPVAVSDADADLEARLENLRRQ---CSFCVGTAKRNRD-GLPEDLIS CADCGNSGHPSCLHFSQDLTERVKNLRWQCIECKMCSQCGESGKEDNMLFCDACDRGFHM ECCQPPLKKPPEG-------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLTPSGTTPTGQKAMAMAT PTPGHLMSMTPEQMQAYTLKREIDERNRPLSDEELDTMFPPGYKVLQPPAGYIPIRTPAR KLTATPTPMAGTPTGFRMQTQIVDMQPKGNLPILKPDDIQYFDRKIMKLLLKIKNGTPPM RKAALRQITDKAREFGAGPLFNQILPLLMSPTLEDQERHLLVKVIDRILYKLDDLVRPYV HKILVVIEPLLIDEDYYARVEGREIISNLAKAAGLATMISTMRPDIDNMDEYVRNTTARA FAVVASALGIPSLLPFLKAVCRSKKSWQARHTGIKIVQQIAILMGCAILPHLKNLVEIIE HGLVDEQQKVRTITALALAALAEAATPYGIESFDSVLKPLWKGIRQHRGKGLAAFLKAIG YLIPLMDAEYANYYTREVMLILVREFQSPDEEMKKIVLKVVKQCCATDGVEPQYIKEEIL PPFFKHFWNQRMAMERRNYRQLVDTTVEIANKVGAAEIVSRVVDDLKDEAEQYRKMVMET IEKIMANLGSADIDSRLEEQLIDGILYAFQEQTTEDVVMLNGFGTVVNALGKRVKPYLPQ ICGTILWRLNNKSAKVRQQAADLISRIAIVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLG SILGALKSIVNVIGMTKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGPEFVS AREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVC TTVAIAIVAETCSPFTVLPALMNEYRVPELNVQNGVLKSLSFMFEYIGEMGKDYIYAVTP LLEDALMDRDLVHRQTAMAAIQHMALGVYGFGCEDALTHLLNHVWPNIFETSPHVVQAFM GSVEGVRVGLGPSKVLQYALQGLFHPARKVRDVYWKVYNTVYIGAQDAMIPSYPRTANDE KNHYLRYELDYVL----------------------------------------------- ------------------------------------------------------------ -----YISTSKQMDLLQNFYETTLDALKEAKNDRLWFKTNTKLGKLYFDREEFGKLQKIL KQLHQSCQTDDGEDDLKKGTQLLEIYALE------------------------------- --------------------------------------PRRTTCLKYLVLANMLMKSGIN PFDSQEAKPYKNDPEILAMTNLVSAYQNNDINEFEKILKTNRRNIMED------------ ------------------------------------------------------------ ----------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXX----------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------FTGV IVATATGKITPWTGRFYTLLDPSYAKNNIPIIASVSEHQPTTWSSFYFDLQMLVFLFPAG LYYCFKKLTDANIFIIMYGITSIYFAGVMVRLMLVLAPVMCILSGIAVSATLNTFMKNLD IPKKGDTNYPIKNEIATGVVLLVTGFLITYTFHCTWVTSEAYSSPSIVLSARAGDGGRII FDDFREAYYWLRHNTPEDAKVMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMAS TEDKAYEIMRELDVNYVLVIFGGLTGYSSDDINKFLWMVRIGGSTDRGAHIKEHDYYTPQ GEFRIDKEGSPVLLNCLMYKMCYYRFGSVYTETGKPTGYDRVRNAEIGNKDFELDVLEEA YTTEHWLVRIFKVKDLENRGN--------------------------------------- -------------------------------------------------------ANQEV RILGENYSLQDEEDSRHGQVGRLWISEARYRIEVNRVPSGNWILMEGIDEPVVKTATITE PSGNEEAHIFRPLKFNTSSVIKIAVEP--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------VLAKRRGHVTQDAPVPGSP LYTIKAFIPAIDSFGFETDLRTHTQGQAFCLSVFHHWQIVPGDPLDKSIVIRPL------ ---------------------------------------------QETFNLFDNRGDGKI YAHQLGEVLRAMGQNPTEAEVKKCNDPDFRISFEMFLPILATISKNRDNSSMEDFVEGFR VFDKEQNGTISSAELRHLLTSLGERLHDDEVEQLLINQEDSQGNVNYEEFVKSVLSG--- LTFNIDNGYLEGLVRGFKGGVLKQTDYLNLVQCETLEDLKLHLQSTDYGNFLANEASPLT VSVIDDKLKEKLVVEFQHMRNQAVEPLATFMDYITYSYMIDNIILLITGTLHQRAIAELI PKCHPLGSFEQMEAIHIAATPAELYNAVLVDTPLAPYFIDCISEADLDEMNIEIIRNTLY KAYLEDFYKFCEQMGGATADVMCEALAFEADRRAFIITINSFGTELTKDDRAKLYPRCGK LHPDGLAALARADDYEQVRAVAEYYGEYRALFDGAGTNPGEKTLEDKFFEHEVMLMKNAF MQQFHFGVFYAYVKLKEQECRNIIWIAECVAQRHRAKIDSYIPIF--------------- -----------------------LSVGLGTCVYLWSACTSQVTRLCDLSCDGDSVTSVSW SERGHLVSVGTHKGFVQIWDVAANKRVAVLEGHSARVGALAWNADILSSGSRDRLILQRD VRTPSVVPERRLTGHRQEVCGLKWSPDHQHLASGGNDNKLFVWNMTSPSPVQTYTEHIAA VKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCVDTGSQVCNLAWSKHSNELVST HGYSQNQILVWKYPSLVQIAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTR STKESNSVLNMFTRIRILTIIGLYYCLSGQGYRFDIGWLLGETSPYLWANLGIGLSISLS VVGAAWGIYTTGSSILGGGVKAPRIRTKNLVSIIFCEAVAIYGIIMAIVISNSSNYAAGY MMFGAGLTVGLSNLFCGVCVGIVGSGAALADAQNSSLFVKILIVEIFGSAIGLFGVIVGI LQSTHAKMGN-----------------------------------NKGAFRIKIDFPAEY PFKPPKITFQTKIYHPNIDEKGQVCLPIISAENWKPATKTDQVIQSLVALVNDPEPEHPL RADLAEEYSKDKKKFNKNAEEYTKKYSEKRPSEGASKTFPMQCSALRKNGFVLLKGKPCK IVEMSTSKTGKHGHAKVHMVGLDIFTGKKCEDICPSTHNMEVPNVTRQEYDVIDFDEGFF TLMDDSGETRMDLKIEATVVKAMENEIVTTLK---GKLLGPK------------------ ------------------------------------------------------------ -------------GVCVDNNGHIIVVDNKNSRIQVFDSQGSFLSYINLYGPQGLAITEEG NVVVADSGNPCVKVYRYLMAAGPIAERNQDATVYVGGLDEKVSEAILWELFLQAGPVVNV HMPKDRITQAHQGYGFVEFMGEEDADYAIKIMNMIKLYGKPIRVNKASAHQKNLDVGANI FIGNLDPEVDEKLLYDVFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIESM NGQFLCNRAISISYAFKKDSKGERHGTPAERLLAAQNPLSQADRPHQLFADAPPPPTQVP -APPPPPPSSSATSMPPPQMPPTGVPPPPMPPPG-GPPPGMPPPPPPPGMPPPPPPMGMP PPGPPPPGMGPPRGMGPPPGKVEAKKTVNPLFEKRPKNFGIGQDIQPKRDLSRFVRWPKY IRLQRQRAILYQRLKVPPSINQFTQALDRQTAMQLFRLLDKYRPETKQQKKARLTARAEQ RAKGKDDVPTKRPPVVRSGVNTVTTLVEQKKAQLVIIAHDVDPVEIVLFLPALCRKMGVP YCIVLGRVVRRKTVTCLALTTVNQEDRSGLNKLIDAVKTNFNERFDEIRRHWGGGVMGAK SQARINKIEKAKAKELVHKMRYVAAYLLAVLGGNNSPKATDIKKILSSVGIDADDACIKK VIGQLEGKDLEQLIAEGQSKLASVPSGGAAPAAEEKKEESGDDDMGFGLFD--------- ------------------------------------------------------------ ------------------------------------------------------GVPLYR HIADLAGNKDVILPVPAFNIINGGSHAGNKLAMQEFMILPTGASNFREAMRMGSETYHHL KKVIKDKYGQDACNVGDEGGFAPNIQNNFEGLELVRIAIEKAGYTGKIQIGMDVAASEFC KKYDLDFKNPKSEPAHWLSSDQLFAVYKEFIEKYPVVSIEDAFDQDDWDAWTKMNAIQLV GDDLLVTNPKRVQEGIDRKACNCLLLKVNQIGSVTESIKACKMSQDNGWGVMVSHRSGET EDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELGDKARYAGTAFRNP----- ------------------------------------------------------------ ---------------------------------------------VMCTTLKVLQHLVVS SDKVGESLVAYYRQILPVFNTFKNKNLNSGDGIDYCQQKRENIGDLIQETLEAFERYGGE DAFINIKYMVPTYESCM------------------------------------------- ----------------------------------------QEAITNAITDLISEISLLEE RFREAIREKQDGD----------------------------------------------- -------------SAQQGGYYCNVCYCVVKDSINFLDHINGKKHQRNLGMSMRIERSSLD QVRQRFEMNKKKQEEKKKEYVFEERVKELREEEEKQKAYRREKRKDRKRRAQDAEGDPDM AALMGFSGFGSSKKMGCTMSAEERAAFERSKQIEKNLKEDGLQAAKDIKLLLLGAGESGK STIVKQMKIIHEGGFTNEDNKQFKPVVYSNTIQSLVAIIRAMGTLNIAFGDSERESDAKM VLDVIARMEDTEPFSEELLQAMKRLWADSGVQECFGRSNEYQLNDSAK------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YHS TFLNPPQLTGNMALLPLRTQFKGPAMDIIDEALYYFKANVFFKNYEIKSEADRTLIYITL YITECLKKLQRCQSRNQGLKEMHTLAINRFYLPGEAQFPLNAMYTRPANRAEEDTMRAY- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GNKSDLEAQRDVTYE EAKQFAEENGLMFLECSAKTGENVEDAFLDTAKKIYQNIQDGSLDLNAAESGVQHKPSTP RNALNTDQSQKQDSCSC-----------GSVKGTIHLEQQEATKLTGEISGLTPGKHGFH VHEFGDNTNGCISAGAHYNPHGKEHAAPEDTDRHVGDLGNVEAGTIQITDSQVSLTGPLS VIGRTIVVHADIDDLGKGGHELSKTTGNAGGRLACGVIGITKMVNFTIDEIREIMDKKKN IRNMSVIAHVDHGKSTLTDSLVSKAGIIAGAKAGEARFTDTRKDEQDRCITIKSTAISMF YHLPESDALSDFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQA IAERIKPVLFMNKMDLALLTLQLDPEDLYQTFQRTVENVNVIIATYGEDGGPMGEVMVDP AKGTVGFGSGLHGWAFTLKQFSEMYSSKFGIEEHKLMKRLWGDQFYNYNRGFTQYILDPI YKVFEACMTKAEALKLVEKVGIKLTLEEKE-QEKQLLKTVMRKWLPAGDALLQMICIHLP SPVTAQRYRMELLYEGPMDDELGKATKNCDAEGPLCMYVSKMVPTSDKGRFYAFGRVFSG TVSTGMKVRIMGPNYTPIKNIQRTILMMGRYVEPIEDVPCGNICGLVGVDQFLVKTGTIT TYEQAHNLKVMKFSVSPVVRVAVECKNPSELPKLVEGLKRLSKSDPMVQCIIEESGEHII AGAGELHLEICLKDLEEDHACIPIKVSEPVVSYRETVTEESSVTCLSKSPNKHNRLFMRA APMPEELSEDIDKGDVTPRQELKERARYLADKYDYDVTEARKIWCFGPEGTGPNLVIDCT KGVQYLNEIKDSVVAGFQWASKEGVLCEENMRGCRFNIHDVTLHADAIHRGGGQIIPTAR RVFYACVLTAAPRLLEPIYLVEIQCPENAVGGIYSCLNKRRGHVNENLQVPGTPMFMVKA YLPVNESFGFTADLRSSTGGQAFPQCVFDHWQVYVITDTRKRKGLKEGIPPVENYLDKMM LPLSLLRTAVNHPMLVELKNGETYNGHLVSCDNWMNINLREVICTSRDGDRFWRMPECYI RGSTIKYLRIPDEVIDMVKEEVIQKSKGRGDLRRGGRGGPGRGAFGNRGGRGGGGGRGGG GG-NEFKLNNAPTDGVSAVKFEPKSSQFLLASSWDCWVRLYDVNANNLRLKYSHSSPVLD CCFHDPVHAYSGGLDKTLKMFDFNTSSETQVGHHDAAIRCVEFCPEVNVVVTGSWDSSVK LWDPRTPCSAGSFSQPDKVYTLAVCGDRLVVGTAGRRVLV-------------------- --------NKQGYVLSSIEGRVAVEYLDPSPEIQKRKYAFKCHRLKEDGMEKIYPVNAIS FHYLHNTFATGGSDG--------------------------------------------- --------------------MDFQHRAGGKTGTGGVASASESNRDRRERLRQLALETIDI NKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQANLARRAAKEAKESPAQPAPE KPRVDIKKFVKIGRPGYKVTKQRDPETGQQSLLYQIDYPEIVETINPRHRFMAAYEQKVE PPDRKWQYLLFAAEPYETIAFKVPSREVDKEPKKFWTYWNKETKQFFMQFAFKHEPKPPT GPPPGGPPPPPRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSKRESVGTVIGIDLGTTY SCVGVFKNGRVEIIANDQGNRITPSYVAFTTEGERLIGDAAKNQLTTNPENTVFDVKRLI GRLWDERSVQHDLKYFPFKVINKNNKPHVEVGVGSEQKVFAPEEISAMILIKMKETAEAY LGKEITNAVVTVPAYFNDAQRQATKDAGMIAGLNVMRIINEPTAAAIAYGLDKKEGEKNI LVFDLGGGTFDVTLLTIDNGVFEVLSTNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRK SNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTRARFEELNMDLFRSTMK PVQKVLEDADLRKDEVDEIVLVGGSTRIPKVQQLVKDFFNGKEPSRGINPDEAVAFGAAV QAGVLSGEEDTGDLVLLDVNPLTLGIETVGGVMTKLIPRNTVIPTKKSQIFSTAADNQPT VTIQVYEGERPMTKDNHILGKFDLTGIPPAPRGVPQIEVTFEIDVNGILKVSAEDKGTGN KEKIVINNDQNRLSPEDIERMINDAEKFADDDKKVKERVEARNELESYAYSLKNQIGDKE KLGGKLSDEDKETIEKAINEHIEWLEANQEADTEDFQTHKKELESIVQPIMSKLYEGAPP PQGGEDYD------EDPELEAIKARVREMEEEAEKLKEMQSEVEKQMSLEEKLDADTRSI YVGNVDYGATAEELEAHFHGCGSINRVTILCDKFTGHPKGFAYIEFADKDSVATAQALDE SLFRGRQIKVSAKRTNRPGISSTNRPPRGRYRRPRGS-YHYGYQPRPR--GRFRPRRASW YSPYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXX------------------------------------YMVYMFKYDSTHGP YKGEVKLVVDGNAIQVFMEMKPDAIPWGTAGAEYVVESTGVFTTCAKAEAHIKGGAKKVI ISAPSADAPMFVMGVNEDKYDPSMPIISNASCTTNCLAPLAKVVNDNFGILEGLMTTVHA FTATQKTVDGPSAKAWRDGRTASQNIIPASTGAAKAVGKVIPDLNGKLTGMAFRVPVPDV SVVDLTCRLKKEATYDQIKAAVKGPMKGFLGYTEDQVVSSDFIGSTHSSVFDARAGIALS PTFVKLITWYDNEYGYSCRVVDLIRYIYGRDSDDLETAILRRKERPNRLLVEEAVNEDNS VVSLSQAKMDELQLFRGDTVLLKGKRRRETVCIVLSDDTVADDKIRINRCVRNNLRVRLG DVVSIQACQDVKYGKRVHVLPIDDTVEGLTGNLFEVYLKPYFLEAYRPVRKGDIFLVRGG MRAVEFKVIETDPSPYCIVAPDTVIHCEGEAVKREEEEEALNEVGYDDIGGCRKQLAQIK EMVELPLRHPQLFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSK LAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQ RSHVIVMAATNRPNSVDPALRRFGRFDREVDIGIPDATGRLEILRIHTKNMKLADDVDLE QVAAETHGHVGADLAALCSEAALQQIREKMDLIDLEDESIDAEVLDSLAVTQEDFRWALS KSNPSALRETAVEVPNVSWEDIGGLENVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFY GPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANIREIFDKARSAAPCVLFFD ELDSIAKARGGNVGDGGGAADRVINQLLTEMDGMSSKKNVFIIGATNRPDIIDPAILRPG RLDQLIYIPLPDEKSRMSILKANLRKTPVSQDIDLSYLATNTKGFSGADLTEICQRACKM AIRESIEQEIRREKERAQNPDDFDPVPEIRRDHFEESMKFARRSVTDNDIRKYEMFAQTL QQSRGFGG------------------NAMKDVEVTSPPDDSVSSIAFSPGVLPSTYLIAG SWDNNVRCWEVQQSGQTIPKAQQTHTGPVLDVCWSDDGTKVFTASCDKTAKMWDLNSNQA MQVAQHEAPIKVAKWIKAPNYSCLMTGSWDKT---------------------------- ------------------------------------------------------------ ------------------------QDIFAVNDIAFHPVHGTLATVGADGRFSFWDKDART KLKTSEQFDQPISCSTFNAQGNIFAYASSYDWSKGHEFFDPQKMKPHIFLRSCYDELKPS QKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMED QEILTTLKILIIGESGVGKSSLLLRFTDDTFDPEQSATIGVDFKVKTLAVDGNRAKLAIW DTAGQERFRTLTPSYYRGAQGVILVYDVCSKQSFNRLDAWLNELETFSTKHDIVKMLVGN KIDMDKRDVTREEGLKFARKHHMLFIEASAKTREGVQCAFEELVEKIIQTPGLWETDGLS LGSVIWSIINGSFCSFKVKTEHQKFCRNEYSLTGLCNRSSCPLANSQYATVREEKGVCYL YLKTIERAAFPARLWEKIKLSRNYEKALKQIDDNLIYWPRYMIHKCKQRFTKITQYLIRM RKLQLKRQKKLVPLSQKVERREKRRETKALVAAQLENAIEKELLDRLKQGTYGDIYNFPQ HAFDKALEQEEVDIESDSEQEIEYV--EELEESDVSDIEFSQARMKAQTRMKTFSIYRWD PDKAGDKPHMQSYQVDLNACGPMVLDALIKIKNEDDPTLTFRRSCREGICGSCSMNINGA NTLACLCKIDSNTSKTSKIYPLPHMYVVKDLVPDMNNFYAQYKYIEPYLKKKDLNEDDYG KEPLKQSPEDRAKLDGMYECILCACCSTSCPSYWWNGDKYLGPAVIMQAYRWIMDSRDDF GAERLEMLKDKWSLYRCHTIMNCTKTCPKGLNPGAAIAEMKKLMLGMESKGIPRQ----- ------------------------------------------------------------ -------------------------------------------------------IPEQP PHHILFLTNLPEETNEMMLSMLFNQFPGFKEVRLVPSRHDIAFVEFENEVQAGAAKDALQ GFKITPTNAMKISFAKKMDSQGRKVVICDNGTGFVKTGYAGSNFPAHIFPSLVGRPILRS NTKVGDIEIRDLMIGDEASQLRSMLEVNYPMENGIVRSWEDMIHLYDYTFGPQKLNLNPR ECKLLLTEPPMNPTKNREKMIEVMFEHYQFDGLYIAIQAVLTLYAQGLLTGVVVDSGDGV THICPVYDGFALPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMMKEKLCYV GYDIEQEQKLALETTVLVESYTLPDGRVIKVGGERFEAPEALFQPHLINVEGPGVAELLF NTINAADIDTRPEFYKHIVLSGGSTMYPGLPSRLEREIKQLYLERVLKGDREKLSKFKIR IEDPPRRKHMVFLGGAVLADIMKDKETFWMTRKEYQEKGLKVMEKLGVSMADTTGKPIKC RAAVAWEAKKPLSVETIEVAPPQAGEVRIKVLHTGVCHTDAYTLDGFDPEGLFPVVLGHE GGGVVESVGQGVTSLKPGDHVIPLYIPQCKDCKFCKNPKTNLCSKIRGTQGKGVMPDGTS RFTCKDQSLYHFMGTSTFSEYTVVAEISVAKVDQAAPLDKVCLLGCGISTGYGAALNTAK VEPGSTCAVWGLGAV--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------DWNDMERIWQYIYSKDQLQTFSEEHPVLLTEAPLNPRRNR EKAAEIFFETFNVPALFISMQAVLSLYATGRTTGVVLDAGDGVTHAVPIYEGFAMP---- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------KIRISAPQERLYSTWIGGSILASLDTFKKMWVSKR EYEEEGVRAIHRKTF---KVSKVVVHPLVLLSVVDHFNRMGKVGNVKRVVGVLLGSTRQG VLDVSNSFAVPFDEDDKDKSVWFLDHDYLENMYGMFKKVNAREKVVGWYHTGPKLHQNDV KINELMRRYNPNSVLVIIDAKPKDLGLPTEGYIAVEEVHDDGTPTSKTFEHVPSEIGAEE AEEVGVEHLLRDIKDTTVGTLSQRVTNQLMGIKGLHSQVFEIHAYLEKVVAGQLPINHQI IYQLQDIFNLLPDINLQEFVKAVYVKTNDQMLVVYLASLIRSVIALHNLINNKLQNRDAE KNEGKPKSMGLLFSKLWNLFTNEEHKVIIVGLDNAGKTTILYQFLMNEVVHTSPTIGSNV EEVIWKNIHFLMWDIGGQESLRAAWSTYYTNAEFVILVVDSTDRERLSITKEELYKMLAC EDLKKAAVLIFANKQDLKGAMSSAEISQQLNLTSIKDHGWHIQACCALTGEGLYQGLEWI TNHIRRRAVPIRRVLLNDPSQLPSDYSSTPGGTLFSTTPGGTRIIYDRNFLMQCRNSPLA KSPPPNMAKIPGVTSPPPPGKRKEIYKYEAPWTLYSMNWSVRPDKRFRLAVGSFVEEYNN KVQIVALDEETSEFTPRSTFDHPYPTTKIMWIPDNKGVFPDLLATSGDYLRVW------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------ADDHQAL IWDIQQMPRAIEDPILAYTAAGEINQIQWSSTQPDWISICYNNCMEILRVRNFSSSQKVA VLGASGGIGQPMSLLLKMNPRVSELSLYDIVNTPGVAADLSHCSTRAKVTAFNGPEELGP ALKGCEVVVIPAGVPRKPGMTRDDLFNTNASIVMNLADAAAQHCPKAMVCIIANPVNSTV PIVSEIYKKRGVYNPKTIFGVTTLDIVRANTFIADLKGLDVNQVNCPVVGGHAGVTIVPL ISQCTPPVSFPEEERQKLTERIQDAGTEVVKAKAGAGSATLSMAFAGARFASSLLDALNG EEGIVECTYVASDETEASYFSTPVLLGKSGIEKNLGLGKMLEYEANLVKNAMPELKASIQ KGVDFVQKNFDRGKDFNIKTRIITDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFAS TLSHLRRLNSPVGRDGKLARPRQLHNTQWGMICPAETPEGGAVGLVKNLALMAYISVGSQ PSPILEFLEEWSMENLEEIAPSAIADATKIFVNGCWVGIHRDPEQLMNTLKKLRRQMDII VSEVSMVRDIRDREIRIYTDAGRICRPLLIVENQKLLLKKRHVDLLKEREYNNYRWQDLV ASGVVEYIDTMEEECIMVAMSPEDLQEKGVGYCSTYTHCEIHPSMILGVCASIIPFPDHN QSPRNTYQSAMGKQAMGVYITNFHVRMDSQANVLFYPQKPLVTTRSMEYLRFRELPAGVN AIVAIASYTGYNQEDSVILNESAVDRGLFRSAFYRAYKDAECKRGMDQEEMFEKPDRSNV TGMRGAVYDKLDDDGIIAPGTRVSGDDVLIGKTITLPQDEDELQGATNKYTKRDSSVFMR RTETGIVDQVMVTINQEGYKFVKIRVRTVKTPQIGDKFASRHGQKGTCGIRYRQEDMPFT CEGLTPDIIVNPHAIPSRMTIGHLIECLQGKVSANKGEIGDATPFNDTVNVQKISNLLHE YGYHQRGNEVLFNGHTGRKLNAQIFLGPTYYQRLKHMVDDKIHSRARGPVQILNRQPMEG RSRDGGLRFGEMERDCQIAHGAAQFLRERLFEASDPYRCHVCNICGLICIANLRNNTFEC RGCKNKTQISQIRMPYACKLLFQELMSMSISPRMMT-ISPISGGFSFENVSRNTLLAKGF SAPKAYKTGTTIAGVIYKDGVVLGADTRATEDTIVADKNCSKIHYLAPNMYCCGAGTAAD TEMTTQMISSQLELHRLNTGRTPRVCTANRLLKQMLFRYQGYISAALVLGGVDNTGPHLY SIYPHGSTDALPYVTMGSGSLAAMAVFEDGYKPDMSRDDAVALVQQAIKGGIFHDLGSGS NVDICVITSAVDHIRPFEKCCFKGERTNEYDYKPGTTPVLTKSIKKLDDILVMSKVTFKI TLTSDPKLPYKVLSVPEQTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPAQSAGNVFL KHGSELRLIPRDRVGH---------YIVALILSAFLIFFVIYHIIAFDELKTDYKNPIDQ CNSLNPLVLPEYGLHMFYNILFLFAGQWGTLLLNAPLLAYHVHRYMHRPVMSGPGLYDPT ------------KEGWIKLAFYLLSFFYYLYSMIYVLVSSMGLLTILKKMKQKEKEVRLL MLGLDNAGKTTILKKFNGEDINTISPTLGFNIKTLEHRGFKLNVWDVGGQKSLRSYWRNY FESTDGLIWVVDCADRRRLEDCKRELEALLLEERLAGATLLVFANK-------------- -----------------------------------------------------------N YYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATQEEMTKFHSDDYIKFLRSIRP DNMSEYNKQMQRFNVGEDCPVFDGMYEFCQLSTGGSVAGAVKLNKQATDIALNWAGGLHH AKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY GEYFPGTGDLRDIGAGKGKYYAVNFPLRDGIEDESYEHIFQPIMSRVMEMYQPSAVVLQC GADSLSGD------------------------------------------------VALG VEIANELPYNDYFEYYGPDFKLHISPSNMANQNTPEYLDKIKTRLFENLRMLPHAPGVQM SDIPEDALNDEHNPEERISIRASDKRIACDEEFSDSEDEGESGRRHRESFKQRKRDTRAF ECNICLDTAKDAVVSMCGHLFCWPCLHQWLETRPQRQVCPVCKAGISKDKVIPLYGRGST NQQDPREKLPPRPPGQRSEPENNSSFPGFGFGFQMSFG---------------------- --------------------------------MYALVHKQETGHEDSIWSCAWAKSEKDG VENIVTGSVDDSVKVWKWQDLELRHTLEGHQLGVVSVDINIHGTMAASSSLDAHIRLWDL EVGKQVKAIDAGPVDAWTICFSPDSRYLASGSHSGKIHLFGVESGKKESQLDTRGKFTLS IAYSPDGRYIACGAIDGIINIFDMTTGKLLEGHAMPIRGLCFSPDSQLLVTASDDGHIKI YDVQHANLAGTLSGHGSWVLNVAFSP---------------------------------- -----------------------------ESDEEFDARYEAYFNRPDIDGWDLRKGMNDL MAYDLVPEPKIVVAAMKACRRVDDYALAVRYLEAVKDKCGPRVTTIWPYMLNQIQPTLEE LGILTPEQMGYDKPELALQDVMDIVVRMRGLPWSANADEIMEFLSDCDICGGKSGIHFTY VRDGRPSGEAYVEMSTEEDVEKALTRDKQHMGKRYVEVFRSKRSEMEWVVKRSGPNQDAV IRLRGLPFGCSKEEVAHFFSGLEIVPNGITLLQDHQGRTTGDAYVQFASQEIAEKAQQKH KERIGHRYIEIFKSSLMEVRNNHESQTGHCVHMRGLPFAANEQDILDFFKPLNPVNVAIH YNNGRASGEADVDFATHDEAKEAMNKDRAAMQHRYIELFFKDKDKPSQIRLSNITAAKAI ADAIRTSLGPRGMDKMIQSGNGDVTITNDGATILKEMQVLHPAAKMLVELSKAQDVEAGD GTTTVVVVAGSLLDAAQKLLAKGIHPTTISESFQQASTKSVEILEGMSTPLELSDRESLL KSASTSLNSKVVSQYSNILSPLCVDAVMKVTDPATDVNVDLRDIKVIRRLGGTVEDTELI DGIVFDTKAAGDGGPSRIEKAKIGLIQFCISPPKTDMENQVIVSDYTQMDRVLREERQYI LNIVKQIKKAGCNVLLIQKSILRDAINDLALHFLAKMKIMVIKDVEREDIEFICKSIGCK PAASLDHFQPEVLGSAEMVEEVQAGSGKVVKITGTQNQGKTMSILVRGSNKLVLEEAERS IHDALCVIRCLVKKRALIAGGGAPEIELSLRLMEHAQTLTGMEQYCFKAFAESLEIIPFT LAENAGLNPIATVTELRNKHAQGEKTAGINVRKGAITNILEENVVQPLLVSTSAVHLAAE TVRSILKIDDIVNCMMILLEINNRIIEDTLTLKFNNVLQGNKPDLVDITIADFDGVLYHI SNPDNDKSKIRVSISLKFYKDLQEHGADDLIKREYGPFITKAEDGYNVSLLYDDNIPANH LEVIKKAGLLKRNCFASVFEKYFEFQEKHKRAVIHYRDDETMYVEAKKDRVTVIFSTVFK DDDDIVIGKVFMQEFKEGRRRYQQAPQVLFSHKEPPLELQSTDAKTGDNIGYITFVLFPR HGSRENTINLIHTLRDYLHYHIKCSKAYIHSRMRAKTSDFLKVLNRARPDSKEKEKKTI- ---------------------------------------RRYPKLKEVDDVLGGSAAWEN VDSTEETCPKCGHNRAFFMQIQTRSADEPMTTFYKCCEMTCGHRWRKTVFGPMKDEDRIF TNLYGRHDWKLKGAISRGDWYKTKEILLKGHEWIQKEVITSGLRGRGGAGFPTGMKWTFM NKPDDGRPKYLVVNADEGEPGTCKDREIMRHDPHKLVEGCLVAGRGMNARAAYIYIRGEF YNEASNMQIAINEAYKAGFLGKNACGSGFDFDIYMHRGAGAYVCGEETSLIESLEGKPGK PRLKPPFPADVGVFGCPSTVNNVETIAVAPTICRRGGDWFASFGRDRNRDVMMDFDALVQ HQTALGTAAVIVMNKQADIVDCINRLMEFYKHESCGQCTPCREGINWMYQMTQRFVTGNA QPAEIDMIYEISKQVEGHTICALGDGAAWPVQGLVRHFRPELERRMKEFQEKKYTQEQVD EMNQQLNQTRSQRVRAAMFPETLEEGVQIPSTQIHPEQPTAVQRLAEPSQMLKHAVVNLI NYQDDADLATRAIPELTKLLNDEDQVVVSQAAMMVHQLSKKEASRHAIMNSPQMIAALVR AMSNTNDVETTRCAAGTLHNLSHHRQGLLAIFKSGGIPALVKLLSNPIESVLFYAVTTLH NLLLHQEGSKMAVRLAGGLQKMVALLQRNNVKFLAITTDCLQILAYGNQESKLIILASGG PGELVRIMRSYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGLQALAMHLGHQSQRLVQN CLWTLRNLSDAAGRQESLEGLLQMLVQLLASNDINIVTCAAGILSNLTCNNQRNKVMVCQ VGGIEALVRTILQAGDREDITEPAVCALRHLTSRHPEAEMAQNAVRLHYGLPVLVKLLHP PSRWPLIKAVVGLIRNLALCPANHAPLREHGALPRIVQLLIRAHQDTQKSQSGYVDGVRM EEIVEGTVGALHILAREAHNRAVIRGLNCIPLFVQLLYSPIENIQRVAAGVLCELAADKE GAEIIEQEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRGE QMSADLQWMIIRNNSSYLLKGSTFSREANNLKSKNSFRYNGLVHKKTIGVEAAADGKGLV LVTKKNWRKPSKNYTRTELKRGSRRTLSTLRKVIRNNRYRKDLKMAALRRASALLKSQRE PVLVKTRDEPYYCSQQINIPPELPDILKQFTKAAIRTQPKDVLAWSAAYFRAMANGEMPP VKDRLETPVATQKTDTGLTPGLLRVLNKQLGPRRVVALQVVEEKWKDLALPKEQFDELVR IGSFAGDVEWLKFFALTCSTLGESITDAMKTVCEILTADPDGGPARIPFQLFQDLYRYLA QIDGEITQEHINDVISHLTYEVEKQDGMVQPRNFLNADCPSLA--VDTAQKEQLMEQVKA QIAVANAQELLQKMSDKCFKKCVSKPGASLDNSEQKCVAMCMDRYMDAWSIVSQTYSRRL MKE----MNRLFGRGKDKQPAPNMNDCISNIDSRGESIEKKIAKLDQELAKYKDQMKKMR DGASKNMVKQKAMRVLKQRKMYDQQREQLANQSFNMEQSNYAIQSLKDTKTTVDAMKIGV KEFKKEYKNINIDNIEDLQDTLEDLNEQSQEIQEIMGRSYGMPEIDDDELEAELDALGDE IGLGDD--FLEDSVQAPNAPTGVPGAE--TNKDGVPVDEFGLPQIPAQXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------KPVTCRCGHIFCFTCGENWHDPVKCKWLKKWIKKCDDD SETSNWIPANTKECPKCRATIEKDGGCNHMVCKKCRFDFCWVCLGPWEPHGSSWYNCNRY DEDEAKKARDAQEGSRAALQRYLFYCNRYMNHMQSLKFEHKLYASVKLKMEEMQQHNMSW IEVQFLKKAVDVLCQCRQTLMFTYVFAFYLRKNNQSIIFEENQKDLENATEQLSEYLERD ITGDMLVDIKQKVQDKYRYCESRRKVLLDHVHEGYDRDLWDYQE---------------- ------------------------------------------------------------ ---------------------------------------------FKQTERVYDSCMEAF DCLPLAALMNQQFLCVHGGLSPEIHNLEDIRKLDRFKEPPAFGPMCDLLWSDPLEDFGNE KTTEHFTHNSVRGCSYFYSYAACCDFLQQNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSL ITIFSAPNYLDVYNNKAAILKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVT EMLVNVLNICSDDELMTEGDDSFEGAMAARKEIIRNKIRAIGKMARVFQVLREESESVLQ LKGLTPNGLLPIGALSGGKDSLRSALSGFSPSHKISGFEEAKYLDKMNERMPPRK----- ------------------------------------------------------KEDALV TKNLVIGESVYGEKRISVEEGTKIEYRAWNPFRSKLAAAILGGVDNIHMKPGSKVLYLGA ASGTTVSHVSDLVGPDGIVYAVEFSHRSGRDLLNVAKKRTNIVPIIEDARHPHKYRMLVG MVDTIFADVAQPDQARIVAINAHHFLKNTGFIVISIKANCIDSTAQPEAVFAGEVAKLRQ EKIKPKEQITLEPYERDHAVVVGQYRPPSKKMDPQKMKDMAGRLQRGGKGAGLGLGFLAA AGGLVYGLYQSMYTVDGGHRAIIFSRLGGIQPDIYKEGLHFRVPWFHYPIIYDIRARPRK ISSPTGSKDLQIVNISLRVLSRPDAMMLPTMYRQLGTDYDERVLPSICNEVLKSVVAKFN ASQLITQRQQVSLMVRKELTERARDFNIILDDVAITELTFGREYAAAVESKQVAQQEAQR AQFVVEKAIQERQQKIVQAEGEAQAAKMVGEAVTTNPGYLKLRKIRASQNIARTVASSKN RVYLNTGSLMLNIADEGFDKNLE------------------------------------- ---------------------------------------------LVDTFTELGANVRWA ACNIYSTQNEVAAALAENGFSIFAWKGESEDDFWWCIEKCISSDNWQPNMILDDGGDATH LMLKRYPAMFSMVK---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------PDPDT IKMFVGQIPRSMDENDLRKMFEEFGPIYQLNVLRDKVTGQSKGCCFVTFYTRKAALDAQN ALHNIKTMPGMQHPIQMKPADSEKRN-EERKLFIGMLSKKCGENEVRMMFAPFGTIEECT VLREQNGQSKGCAFVTYASRQCAQNAIKSMHHSQTMEGCRAPLVVKFADTQKEKEMKKLQ QMNNVLQMQ--------------------------------------------------- -------------------------VAGVFSTTIMAPGERIKCLLQICAKKLYKEGGIRS IYRGTAATLARDMPASGMYFMTYEWLQHVLTPEGKSRSDLGPRTLFAGGM---------- ------------------------------------------------------------ ----NIFKINNSATTLERAMKQIGTSKDSVQLRDRIHATEQNTNQVIQETAKVFRQFSQV RRSDRQQKLQFERLKNEFQETLQRYNVLQKKVAEKVKSSVIDTDLALIQEREDRIRQLEG DILDINDIFRDLATLVHEQGEVIDTI---------------------------------- -------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXGKKGEKAPTPQEAIQRLRETEEMLSKKSDFLEK KIEEELKTAKKRAALQALKRKKRYDNQLRQIDGTLSTIEFQREALENASTNTEVLRVMGD AAKALKSAHKNMDVDDVHNLMDDVAEQQEIANEISEAISNPVGFGEDVDEDDLMAELEEL EQEELDEQLLQVGNLPSVPTEVEDDMRELEMWASSMQRFHNRVRQILMASGSTTFTKIVN KWNTALIGLMTYFREAVVNTQELLDLLVKCENKIQTRIKIGLNSKMPSRFPPVVFYTPKE LGGLGMLSMGHVLIPQSDLRWSKQTDVGITHFRSGMSHDEDQLIPNLYRYIMPWESEFID SQRVWAEYALRTDMIQALGGVEGILEHTLFKGTYFPTWEGLFWEKASGFEESMKYKKLTN ASKDTMDGATTQKYWLDIQLRWGDYDSHDIERYARAKFLDYTTDNMSIYPSPTGLLIAID LAYNLHSAFGNWFPGCKPLIQQAMAKIMKANPALYVLRERIRKGLQLYSSEPTEPYLSSQ NYG--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------SDEEWVKVEKDLKDLILADYGKKNNVNVASLTQSE IRDIILGMEISAPSAQRQQIAEIEKQTKEQSQLTATTTRTVNKHGDEIITTTLSNYETAT FSSKTEWRVRAISATNLHLRTNHIYVSSDDIKETGYTYILPKNVLKKFIIISDLRAQIAG YLYGVSPPDNPQVKEIRCIVMAPQWGTHQTVHLPNGLPGHDYLKEMEPLGWIHTQPNELP QLSPQDITTHARVMADNPTWDGEKTVIITCSFTPGSCSLTAYKLTPSGYEWGRQNTDKGN NPKGYLPSHYEKVQMLLSDRFLGFFMTPAQGSWNYNFMGVRHDPNMKYELQLSNPKEFYH EVHRPSHFLNFSAIEEGADREDHY--YSETRPNMRLGKESKVICQGFTGKQGTFHSQQAI DYGTNFVGGVSPGKGGKTHLGLPVFNSVKEARAATNCDATVIYVPPQAAAAAIMEAIDAE VPLVVVITEGIPQQDMVRVKHKLLRQNKSRMIGPNCPGIIKPGECKIGIMPGHIHKPGRI GIVSRSGTLTYEAVHQTTQVGLGQTLCVGIGGDPFNGTNFIDCLDVFLKDPGTEGIVMIG EIGGQAEEKAAQFLLENNGPNRKPVASFIAGLTAPPGRRMGHAGAIIAGGKGGAQEKIQA LKDAGVNVTMSPAQMGTSILKAMQDAGK-SSESLKCTLCHERLEDTHFVQCPSVAEHKFC FPCSRESIKRQGAGSEVYCPSGKKCPLVGSNVPWAFMQGEIATILGFGKFMEIGRVAYVA FGPDEGKLIVVVDILDQNRALVDGP--KVVRQCMNFKFLHLTKFKLIPHSARPGVVKKIW EKGEIDKKWAETTWAKKIEQRKKRTTLSDFDRFKLMKAKQARNRLINIEFGKLRKASKKT CPHLLRVFCSTGRHHPLNEYVRGNTPANELQIYTWMDATLKELTGLVKEVNVDARKKGTF FDFAIVFPDNRTPQYRLREIGTTCSGRRGADDGVTLLSRRFQIGDYLNIAITPPR----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------KRLLPKKETKVFIGLSKMQREWYTKILMKDIDVVNGAGKSDKMRLLNILMQ LRKCANHPYLFDGAEPGPPYTTDKHLVDNCGKMVLLDKLLPKFKEEDSRVLIFSQMTRML DILEDYCAWRMYNYCRLDGQTAHEERQRQIDEFNSPGSSKFVFMLSTRAGGLGINLATAD VVILFDSDWNPQVDLQAMDRAHRIGQKKQVRVFRFITENTVEERIVERAEMKLRLDNVVI QQGRLVDQNTNKEVLNMIRHGANHVFASKDSEITEEDIDDLLSKG--------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------EVEG KTPEEVMEYSSVFWERCNELQDIERIMAQIERGEAKIQRRISIKRALDAKMARYRAPFHQ LRIQYGTNKGKNYTEEEDRFLVCMLHKLGFDRENVYDELRTAVRQAPQFRFDWFIKSRTA MELQRRCNTLITLIERENMELEEREKAERKKDTKPSWAEQVEQGEDDVLPPPHEEFDEKK NIKTITEYKFNDDGKKVRVVKVYKLETKKVPKTIARRKTWRKFGSAANDPPGPNPSNTIE DVYMQFVHTKEAEENNPLAKLKVSCRYCKGDHWSKQCPHKDKLELLQDTLARPGKYVPPN LREGANRRGEAM------------------------------------------------ ------------------------------------------------------------ ---------------------FGSKVVNVGGKSVKLQIWDTAGQERFRSVTRSYYRGAAG ALLVYDITSRETYNALTNWLTDARTLASPNIVIILVGNKKDLEAER-------------- --------------------------------------RMGSGIQYGDASLRRLQQRRPE CSC----------------------------------------------EEYVKTGFINL DKPSNPSSHEVVAWIKRILRVEKTGHSGTLDPKVTGCLIVCVERATRLVKSQQSAGKQYV CIFKLHSAVESEKKILQGVEKLTGSLFQRPPLISAVKRQLRVRTIYESKMLQYDQEKHMG VILVDCEAGTYIRTLCVHLGLMLGVGGQMQELRRTRSGVLSEKDNLVTMHDILDAQWLYD HHRDESYLRRVILPLESLLKSHKRIIMKDSAVNAVCYGAKIMLPGVLRYEDGIEINDEVV IVTTKGEAVALAIAQMTSAVMASCDHGMVAKIKRVVMERDTYPRKWGLGPVASRKKQMIK DGLLSEHGKPNEKTPKGWTSSYVDYSASKKRKHDTENGEEKKKKKKKKMAEADWDRKKAP KSGQLKSQAAINTAQRQGLDIDTSKKYTAGKNMQHSAAKNTAKLDRETEELHHDKIGLDV GRLIQQGRQAKNMTQKELATKINEKPQVVNDYEAGRAIPNQQVLSKVERVIGLKLRGRDK GQ-----MLKPKALTQVLSQANTGGVQSSLLLNNEGALLAFSGYGDKDARVTAAIASNIW AAYEKNGRAAFNEEKLKFILMECEDGRVAITRV--------------------------- ------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------- ---------------------RGVILFPWVGKVYDRDIATKSSREVKGRTHTYYQVLLDA RDMPHIRVGTESVTFLSNQENGTLYSIPGLDYVGHEDVLPYMTTEKQPIHNHLFDKFLLQ DGQYMARDTLREWQDKNHPWLELTDVHRETTENIRVTVMPFYIGEVQQTHVYWWRYCIRL ENFSDETVQLRERHWRIFSLSGTLETVRGRGIIGKEPVFSRTQPAFQYTSHVSLQAPSGH MWGTFKMERDDGSTFECRIPPFSLESKHEDGMATAKGANTYNRQNWEESDFPVLCQTCLG DNPYIRMTKEKYGKECKICARPFTVFRWCPGARMRFKRSE-------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------MDVFLMIRRKKTTIFMDAKESTSVLELKRMVQGITKKSPED MRLYKDNKNLGDYGFTSSTARAQAPATVGLSFREYEPLEIAPLSTPPELPDVMKPQESSS SHAQEHLYRYHVVLLRARFDENKGEDVRKAKQLLEEGERELLLKQHYQPFKFADSPGGVA FGRDVKSPDWMLDMWHPLERAQYPEYFARREQRKKEYIERWEKEYGKQEXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAIRLFNNLGKLGLGIAVTAGVVNTALY NVDGGHRAVIFDRFAGVRENIIGEGTHFLIPWVQRPIIFDIRSRARSVPTVTGSKDLQNV NITLRVLFRPLPNKLPKIYTNLGIDYDERVLPSIVNEVLKAVVAQFDAGELITQRELVSS RITEELTNRAGSFGLLLDDISITHLTFGKEFTLAVEMKQVAQQEAEKARYMVEREEQRKK AAIIRAEGDSVAAVLLAKAFGDAGDGLVELRKLEAAEDIAYQLSQSPNVAYLPQNQNVLL NLPMKIIKVNQTVQVPPGVDVTVNARKVTVKGPRGVLRRNFRHMSVDIKTLPGNQVLVEK WFGIKKELAAVRTVCSHIENMCKGVTLGFKYKMRSVYAHFPINLAISENNTLVEVRNFLG EKYTRQVRMLNGVSCTSSTAQKDEIILEGNDIELVSQSAALIQQSTTVHDKDIRKFLDGI YVSEKTTVI--MGCAVSSEDKAAAERSKQIDRGLRMDGEKASREVKLLLLGAGESGKSTI VKQMKIIHEKGYTTEECMQYRPVVFSNTVQSMIAIIRAMGQLKIDFGHPDRADDARQLFA LAGSAEEGELSNELASVMVRLWKDTGVQDCFGRSREYQLNDSAEYYLNALERISQPAYVP TEQDVLR----------------------------------------------------- ------------------------------------------DLFEEKIKKSSLSICFQE YTGPNTYEDAAAYIQVQFNKRKETKEIYTHFTCATDTNNVQFVFDAVTD----------- --XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXX------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------EVPSNKDVTSLDWNCDGTLLATGSYDGFARIWSTDGRLVSTLGQHKGPIFA LKWNKKGNYILSAGVDKTTIIWDASSGHCTQQFAFHSAPALDVDWQSNTSFASCSTDQCI HVCKLGQDKPIKTFQGHTNEVNAIKWDPQGNLLASCSDDMTLKIWSMKQDSCVHDLQAHS KEIYTIKWSPTGPGTNNPNSALILASASFDSTVRLWDVDRGVCIHTLTRHQEPVYSVAFS PDGKYLASGSFDKCVHIWNVQTGALVHSYKGTGGIFEVCWNHRGDKVGASA--------- ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX--------------------------------------------- ------------------------------------------------------------ ------------GQAFTIMLVYVWSRRNPYIRMNFFGLLNFQAPYLPWVLLGFSLLLGNS IVVDLMGIAIGHMYYFLEDVFPQQPGGFKLLRTPGFLKWIFDGPREDPNYQPLAPGGYNW GQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXSSQVRLAHTDVQYPDFSAYRRDDNQAGRKMFSYLTVAGGGVAAAYSAKS IVGHFVSSMSASADVLAVAKIEIKLSDIPEGKNATFKWRNKPLFVRHRSEDEIATEAEVD LSTLRDPQHDNERAQKPEWLILLGVCTHLGCVPIANSGEFGGYYCPCHGSHYDASGRIRK GPAPLNLEIPEYTFLDEATVVVG------------------------------------- -----------------------------------------------------PTVTNWS PAGDEFSLLLENNPLTDFVELPEGHNNLNYSVILCGVLRGALEMVQMEVAVWFVQDQLKG DNITEVRLKFIRRLEDAVPAGED------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVY EMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSTDLKELLRNLLQVDLTKRFGNLRNGVN DIKNNKWFQTTDWIAIYQQKVDAPFIPRCKGPGDFSNFDDYDEEPLRISSNEKCAKEFAD FMFADTILILCISIATAFLGEGLTWLLVYRTDKYKKLKAEVEKQSKKLEKQKEATGDSSD RSTKKKLERQEEKLKNNNR----------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------LNTL IHHCEAVLHLRFSDGIMVTCSKDRSIAVWDMQSPTDINLRRVLVGHRAAVNVVDFDQKYI VSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGLCL R-------------------------------------------------TLVEHSGRVF RLQFDEFQIVSSSHDDTILIWDFLN-----------------------------EDAFNS TFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKS FDNIRNWIRNIE-------------------------------LAIEHGIKFMETSAKAS INVEDAFFTLARDIKAKMDRKLAEGESSADRNVEIWKIKKLIKSLEAARGNGTSMISLII PPKDQISRVAKMLADEFGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVIYCGT IVTDEGKEKKVNIDFEPFRPINTSLYLCDNKFHTEALTALLADDNKFGFIVMDGNGALFG TLSGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAEVAVQLFITNDRP NIAGMVLAGSADFKTELSQSDMFDPRLQAKILKIVDVSYGGENGFNQAIELASEALANVK FIQEKKLIGKYFDEISQDTGKYCFGVDDTLKALEMGSVEILIVWENLDIMRYVLKNHSSE EEKILFLKPEQEKDKTHFTDKESGVELELVDSQPLLEWFANNYKSFGATLEIITDKSQEG AQFVKGFGGIGGILRYQVDFQSLEAVDEFDELYDLDDYITRCSQPLVGKRNKDDERYVQM IMDANAQSHKLYIMDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRK LKDICFPSIEDVHWLSNIEST--LEHIKQILAGAVRIADKVESNKTSVLVHCSDGWDRTA QLTALAMLMLDPFYRTIRGFEVLIEKEWLSFGHKFMHRVGHGEDKHS------------- --------------------------------------------------KTASLWSYVN CQLEEFMNPLYQHVLFPVASLRRIQLWTAYYIRWNPRMRPQEPIHLRNRELLVLKA---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------LAAGFFLPGSAGITDPCETGNVRIHTVMTLDQ QDLVCYTAQTLLRVLSHGGYKQILGLEGNASIATEMSVWEGVVVTPSDKAYEKPE----- ------------------------------------------------------------ ------------------------------------------------------------ --------------ALAGEVNVVPPSRLLALLGQALKWQQHQGLLPPGQTIDVFRGKAAV REQEEEKYPTQLCKTIKFGQKAHVECCQFSPDGQYLVTGSVDGFIE-------------- --AQDNFMMMDDAVLCMCFSRDSEMLVSGGQDGKIKVWKIATGQCLRRFERAHSKGVTCV NFSKDNSQLLSASFDQTIR----------------------------------------- --------------------------------------------------IMNMQGQIVR SFSSGKRDGGDFVCATVSPRGEWIYCVGEDLVLYCFSITTGKLERTLTVHEKDVIGLVHH PHQNLIATYSEDGLLKTWKP---------------TPRLQTFWKYARVELRPPSEMPQVQ QGFQNLIKATTGKWKQVSVKEATLVFVEICCWFTVGEIVGKRALIGYQVPGGVNFDVHXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXX--------------------------------------- ------------------------------------------------------------ ---------------------------LKYIHSANVIHRDLKPSNLLVNENCELKIGDFG MARASSVDEGFHYFMTQYVATRWYRAPELMMSVIEYTTAVDVWSVGCIFA---------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------QFALVIRNNEKLNVHAEELVVGDLIDV KFGDRVPADIRVISAHGFKVDNSSLTGESEPQTRTADFTNDNPLETRNLAFFSTNAVEGT CRGIVVNTGDRTVMGRIANLASGLEVGETPIAREIAHFIHIITGVAVFLGVSFFVIAFIL GYHWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTI CSDKTGTLTQNRMTVAHMWFDNRIVEADTSEDQSNATYDSSSPTWMSLARVSMLCNRAEF KVGQENVPVLKRECNGDASESALLKCVELSIGHVTKFREDNKKVCEIPFNSTNKYQVSIH KDDPRYILVMKGAPERILDRCSTILINGEEKPLSEDWREAFNQAYLELGGLGERVLGFCD YFLPADQFPVGYPFDSDEENFPLTGLRFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVT GDHPITAKAIAKGVGIISEGNETVEDIAARLGIPVSEVNPRDAKACVVHGSDLRDMTPAQ IDEILECHPEIVFARTSPQQKLIIVEGCQRQGQIVAVTGDGVNDSPALKKADIGVAMGIA GSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLLFILAD VPLPLGTITILCIDLGTDLVPAISLAYEQAESDIMKRQPRDPKHDKLVNNRLIGMAYGQI GMIQASGGFFSYFVIMAENGFWPSRLLGIRKEWDSKAVNDLEDSYGQEWTYAQRKVLEYT CHTAFFVSIVIVQWADLMICKTRRNSIIHQGMMNHHMTFGLFFETTLAAFLAYCPGLDKG LRMYPMRFTWWLAPMPFSLAIFIYDEVRKYLLRRTPGGWLEMETYYSFEKLSRGKKIAIG ASAGAVGLATALHELELHPPKFPWTHNGLLESLDHASVRRGYFVYKQVCAACHSMNFMYY RNLVDVCLTEEEAKAEAEEAQVLDGPDEEGNMFERPGKLSDLFPKPYANDEAAKAANNGA LPPDLTYIVNARHGGEDYVFSLLTGYYDAPAGVTVGEGQAYNPYFAGGALGMAQQLFNEG IEYDDGTPATVSQMAKDVCVFLRYSAEPEHDLRKRMGMKAVSILLLVITLFYKKHKWSVL KSRKIAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSE-AS DEEQGPYLGEYEGERNERDERHGLGKATLPSGDTYEGQYENGKRHGQGTYRFKNGARYIG EWMKNKKHGQGMFIYPDGSKYEGSWVDDQRCGQGKYFYVNGDHYDGEWQNHVRHGQGLYT YAETGTKYSGTWREGKREGQGELIHTNHKYVGPFRDDRPEGRGKYVFDIGCQQHGEYIXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXSLEALMFHLSPNQKKCLKEEIHKDVLVTGEFEISEAAGQKARL VVTDSKGHVLYNKEDAEKGKFAFTTEEYDMFEVCFETRMVAGGHGSDREVFLNMKHGVEA KNYADIAKAEKLKPLEVELKKLEDLSESIVNDFAYMRAREEEMRDTNESTHSRVLYFGIF SMVCLLGLATWQVLYLRRFFKAKKLIE--------------------------------- ------------------------------------------------------------ LCCPLFFVVDKVDMCRSAQVERTVKQLERILKSPGCKKVPFRVESDDDAVTAASTFHNDS ICPIFKVSSVSGLNLNLLIKFLNVLPPLQNQERTEHQIDEVYSIAGVGNVVGGTLLRGTV KEGDKLVVGPTDDGQFLPVTIGSIHRNR-----------ASLALTSCPIRKGMVLVSPEL APTSCIEFEADIYLLFHTHYICKGFQTVIHVGNVCQTAKIVSMDKGYIKTNQKAVVVFRF INRPEYIRPGSRLLFREGRTKGMGEVTKIFSFENP------------------------- --------HSASVRRVCVSRDGSRLVTGSDDCKAKVLLTASGKVVSTLKGHTKPLMSVTY GENF---IVTTSEDVTACVYNKENTMPAYILSGHDAPVTCCSLNAEEKLATGSRDMSVKI WNLTTLHQCHNDWVTSCAFSNTDNFMITASNDFTLKLWDQEKIQFTGHMAAINQVAYQYG CIICSSASDDGTIRIWRPIQGNELACLTGHSDRVNAVACAKNGT-ILTSSLDRLWKPDLK KVIGGHEAEVSVAKFSPSGKFLVTGSRDGCLKLWVTEWAVCKYSFQAHDKAVTSVSFIGK EVGFVTGSIDCSLKKWK------------------------------------------- ------------VAVVMTEVPPLFVVEFLHRVMDTFEDYFTECTESIIKENYVIVYEILD EMLDNGFPLATESNILKELIKPPNILRTITDTVTGKSSSVSSTLPTGQLSNVPWRRTGVK YTNNEAYFDVIEEIDAIIDRSGSTVFAEIQGYIDCLIKL--------------------- -----------ERILSFVPPDGNFRLISYHIGTQNMVAIPVYLKHSISFRDGSSGRLDIT VGPKQTMGKSIENVSVEIPFPKVVLNVTLTPTQGKYSFDPVTKVMTWD------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----ALGIDVDQYNLTEESPGISYKPDPLRVPKGSTTPQNWEDYSRYNKDRAEAEMEASK RLREAILHTLQQTENDLNAQKTASEYAYRKRMHDFQQAIKELGWQKQQTEEEIAELEEDI RRLNDDIRAKINPLKLAQTRLENRTYRPNVELCRDNVQYGLCDEVKQLEASKKALEEKLK QAQHALDGLENKLHTINEDLQRKTNSLKLDEQCMQSRNKL---------TNLKEVLVNLV PQHQEEVAKFRKEYGNSKVGEVTVDMMYGGMRGIKGLVTETSVLDPDEGIEFRNHTIPDC QEILPKAPGGEEPLPEGLFWLLVTGQVPTEAQVKALSKEWANRADLPSHVVTMLNNFPSK LHPMAQFSAAITACNSDSKFSQAYADGVNKKLYWEYIYEDSMDLIAKLPTIAAIIYRNLY RDGTSVGAIDPEKDWSANFTSMLGYEDPMFTELMRLYLTIHSDHEGGNVSAHTCHLVGSA LSDPYLSFAAGMDGLAGPLHGLANQEVLVWLTKLKYTEQELKDFIWNTLQSGQVVPGYGH AVLRKTDPRYMCQREFAQKHLPNDPMFKLVSDVYKVVPDILLQQGKAKNPWPNVDAHSGV LLQYYGMTEMNYYTVLFGVSRALGCLASLIWDRALGLPIERPKSMSTEGLAKLVQMPFKP PVTEKCQKCTKSVYAAERMEAGGKIWHKFCFKCSECNMQLNLQNYAQADGILFCKNHYAS VVVAKNKQ---LFVHRDTPENNADIKFEFTPENVKRAEIIIKNYPDGHQAAATIPLLDLA QRQHGWLPISAMHHVADMLKMPRMRVYEVATFYTMFNRNPVGKYLVQICTTTPCMLGGVG SRPILEAIKSKLGIEVGETTSDKLFTLSEVECLGACVNAPMVQINDDYYEDLTVKDIEEI LDDIKAGRKPKPGPR---NGRFASEPLGGLTSLTEPPKGPGFGVRADLMQKYEKLEKIGE GTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHS EKKLTLVFEYCDQDLKKYFDSCNGEMDPDVVKSFMYQLLRGLGFCHSHNVLHRDLKPQNL LINKNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIF AELANAGRPLFPGNDVDDQLKRIFKLLGTPTEDTWPGMTQLPEYKPYPMYHVSQQVVPKL NSKGRELLVNLLVCNPSKRMSAEEGMQHSYFADLNPAIKDDGQFFVHTGPKRGVRYPLQV ECDGWPVEYLEHHPNQEKAKVWMEKNLTDDMKQLYLKRQHRGGRGVIKTKKKQEPQQVCL SRASRGKKKYVTVITGLATYDIDLKDASKYFSTKFSCGSSVTGPDEIVIQGDCKDDLWDV ITEKWSQIDEDSIEDLGDQKR--------------------------------------- -------------------VQFPELRLIQYDCGKLQTMDILLRQLKSGGHRVLIFTQMTK MLDVLEAFLNYHGHRYLRLDGTTKVEQRQALMERFNMDRRIFCFILSTRSGGIGVNLTGA DTVIFYDSDWNPTMDAQAQDRCHRIGQTRDVHIYRLISEKTVEENILKKANQKRLLGDVA IEGGNF-----------------------MALETVPKDLRHLRACLMCSLVKTIDQFEFD GCDNCDPFLHMKSNREAVYDCTSSSFDGMVAMMSPTDSW--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------QNGLVPIVEPEVLPDGDHDLETAQRSTEQVLSFVYKALADH HVFLEGTLLKPNMVTAGQSCATKYTPEQVAAATVTTLQRTVPAAVAGVTFLSGGQSEEDA SVHLDAINKKPWALTFSYGRALQASVLAAWKGSKDNVKAGQDELLKRAKANGLAAMGQYG GGPAGAGQESLFVADHKY------------------------------------------ --------------------------------------KITEEEDPKGVPQFWLTVFKNV EMLSEMVQEHDEPILQHLNEIKVKFSMGFTLEFFFGPNEHFSNSILTKEYGMRAEPDPTD PFSFEGPEIIKCKGCTIDWKKGKNVTVKVIKKVQKHKGRGTKRTVTKTVQNDSFFNFFNP PEVPEGEPDEDLEALLASDFEIGHFLRERVVPRAVLYFTGEALE-EEEGDEED--VILLK EGTDTSQGKPQLISNINACQAIVDAVRTTLGPRGMDKLIVDGNGKATISNDGATIMKLLD IVHPAAKTLVDIAKSQDAEVGDGTTSVVLLAGEFLLHCKPFVEEGVHPQVIIRAFRKATH LAVEKIRQIAVQVKTDPNEQRNLLEKCAATALSSKLVARQKEFFAKITVDAVLQLDELLP LNMIGIKKVQGGGLEDSLLVDGVAFKKTFSYAGFEMQRKMYKNPKIALLNIELELKAEKD NAEIRVETVQEYQSIVDAEWQILYEKLEKIHTAGAKVVLSKLPIGDVATQYFADRDMFCA GRVPEEDLKRTMKACGGSIQTTVATLALGTCEEFEEIQVGGERYNKFSGCPEAKTVTIIL RGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIAGKEQLL IGAMAKALEIIPRQLCDNAGFDATNILNKLRQKHAGTWYGVDITSEDIADNYKACVWEPS IVKINALTAASEAACLILSVDETIKNPKSAQEGPPAGRGRGRPMKRNNMIPNGHFHKDWQ RWVRTWFNQPARKKRRHDNRVKKARMIAPRPVGGPLRPIVRCPTFKYNTRIRAGKGFTLD ELKAAGINKRVAHTIGIAVDFRRRNKSVESLQQNVQRLKEYRSKLILFPKKLSKPKKGDA TEAELKMATQLSGEVMPIVAFTKTDKAQPITADMKKYSAFTAIRQARANKRLYGIRKKKA EEAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXLSCRFYEHRFPEVEDVVMVNVRSIAEMGAYVHLLEYNNIEG MILLSELSRRRIRSINKLIRVGRSECVVVIRVDKDKGYIDLSKRRVSPEEVVKCEEKFAK AKCVNSILRHVGELLKYETDEQLEELYTNTAWYFDRKYKKTGASYDAFKHAVANPEILDE LPLDSETKEVLISNIKRRLTPQAVKIRSDIEVACYGYEGVDAVKSALKEGLSLGTEDMPI KINLIAPPLYVMTTQTLERTEGMARGHQKIQSQQKNAEKLAKMKHDQKKAAAKALTFTCS VCKSQMPDPKTYKQHFENKHPKAALPEELKD----NLHTDMTRQGIMTVPKGHCAACAKP IIGQVITALGKIWHPEHFACVHCKEELGTRNFFERDGQPYCEQDYHNLFSPRCAHCSGPI LDKCVTALDKSWHPEHFFCAQCGRLFGDEGFHEKDGKAYCREDYFDMFAPKCGGCLRPIM DNY--------HPECFICQECHIPFGGGSFFDHEGMPYCETHYHAKRGSLCAGCHKPITG RCITAMYKKFHPEHFVCAFCLKQLNKGTFKEQNEKPYCHPCFVKLF-------------- ---------------------------------------------KDKLLSFGTCFGKFT KTGKFRLHVTALDYLAPYAKYKVWLKPNAEQQFLYGHHVMKSGVGRLTEN---------- -----------------DSRHVDPMTIVMFHQADIGEYLRNEETL--------------- ------------------------------------------------------------ -----VGCHWVILGHSERRNVFGESDQLIGEKIAHALAAGLKVIPCFGEKLEEREAGKTF DVVFSQLKAKDWSRVVLAYEPVWAIGTGRTATPEQAQEVHAALRKWLTENVSADVANSVR ILYGGSVSAGNCRELAGKPDIDGFLVGGAALKPDFIQIINAREREGLLDPAWEKQQRKTF TAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGEQLPKPDRGKMRFHKIANVNKAL QFIESKGVKLVSIGAEEIVDGNVKMTLGMIWTIIVQNFHMSWKDGLAFCALIHRHRPELI DYGKLSRDNPIENLNTAFDVAEKYLDIPRMLDAEDMVNSVKPDERSVMAYVSSYYHAFSG AQQAETAANRICKVLKVNQENERLMEEYERLASDLLEWIRRTTPWLENRTTDNTLPGTQR KLEEFRDYRRQHKPPKLEQKAKLETTFNTLQTRLRLSNRPAYMPTEGKMVSDIANAWKGL ERAEKGFEEWLLSELQRLERLEHLAAKFKHKCDIHEEWSYGKEDLLQAQDFKKCRLNELK ALKKKHEAFESDLAAHQDRVEQIAAIAQELNALDYHDSPAVNARCQRICDQWDLLGTLTG QRRAALDEAERILERIDQLHLEFAKRAAPFNNWMDGAKEDLVDMFIVHTTEEIQGLIDAH EQFKGTLGEADKEFNAIMALLTEVQRISQQYGITGGEDNPYTTLHAQDLAHKWSEVKSLV PQRDTTLQQEMIRQQNNERLRRQFAQKANMVGQWIERHLDAVASVGIQKGSLEDHLNKLK GIEKEVSAFKPNVDELERYNQEVQEAMIFENRHTQYTMETLRVGWEQLLTSVARNINEVE NQILTRDSKGITNEQMDEFRKSFFHFDKTRSRRLEPKEFKACLVSLGYNIRDDRQGEADF QRIMSIVDINHSGYVTFDAFLDFMTREATDTDTAEQVMQSFKILAGDKSYITADILRREL PPDQAEYCIQRMAPYSGRDAIPGALDYSSFSTALYGESDL-----------------RVD FNVPLKGTEITNTQRIDAALPTIKHALDNGAKSVVLMSHLGRPNGCRQEKFSLKPVADCL KQRLGRDVQFLNDCVGADVEAACANPKAGSVILLENLRFHIEEEGKGVDESGQKVKADSK KVEEFRASLSKLGDVYVNDAFGTAHRAHSSMVGCQLPQRASGFLLKKELTYFAKALENPE RPFLAILGGAKVKDKIQLINNMLDKVNEMIIGGGMAYTFLKVLDNMEIGNSLYDEEGAKI VKDLMDKAAKNKVQIHLPSDFVTADKFAEDAAVGTATKATGIPAGSMGLDVGPSSTANFT EAVGRAKTIVWNGPAGVFEFENFAKGTKGLMDAVVHATEKGAVSIIGGGDTATCCAQWKT EDKV-------------------------------------------------------- -----------------------KFHRIIPDFMIQGGDPTGTGRGGASIYGRQFDDELTD ELKHTGAGILSMANSGPNSNGSQFFITLAPTQWLDNKHSIFGRVCSGMTVVKRIGMVETD SNDKPVEDVKI-KRRSRSRDRKRSRSPRNRRKPYKYWDVPPPGFEHITPLQYKAMQGVIP FAGSAISRQARRLYVGNIPFGVTEEMMMDFFNTQMKLAGLAQAEGNPVIACQVNLDKNFA FLEFRSVDETTQAMAFDGINFQGQSLKIRRPRDYQPLPGMAETPSVGVVSTVVQDSPHKI FIGGLPNYLNEDQVKELLTSFGPLKAFNLVKDSGTGLSKGYAFCEYVDQACAGLNGMQLG DKKLIVQRASVGAKNAQQAPVQIQIPGLNLNAVPTEVLCLMNMVVPEELEDEEEYEDILE DVREECSKYGTVKSLEIPRPIKGVEVPGCGKIFVEFNSIIDCQKAQQSLTGRKFSNRVVV TSYYDPDSYHRREFFFPMFDRVLVERLAAEVQTKSGIFIPEKAQQKVLEATVVAVGPGGR NETGSVVPIAVKVGDRVLLPEYGGTKVIMEEKEFHLFREGDILGKFERLKQQIPDIKSSL DIVQHMKSKKEPMKTHFQLSDQVYVKAQVPPTEKVCLWLGANVMLEYTLDDAESLLEKNA ATRSHAVVDEDLGFLRDQTTTIEVNMARVYNWDVKRRQ-----ADEALAKAGLHFDELNK IRVLEPEVGQQTSELKEECKDFLDKMVEFQKIVGTFIELTDNVAKEVEKEKMKAIGSRNQ LKSVTKQREAQQQQLHALIAEKKMQLERLRIQYESLMKEEQDQTEFIEQFILQKRSRSRD RSKRDRESKHSKSRDQKEMTPEERDARTVFCMQLSARIRPRDLEEFFSSVGKVRDVRIIT DNKTRRSKGISYVEFVDTESVPLAIALDGQRLLGVPIIVQPSQAEKNRLAGNSGPMRLYV GSLHFNITEDMLRGIFEPFGKIDDIKLIRDHETNRSQGYGFITFHDSEDAKKALEQLNGF ELAGRPMKVGHVTERTAEASILDTDEMDRAGIDLGATGRLQLMAKLAEGTGFQIPQVAAN ALNMAPAAAAPPIATQCFMLSNMFDPTTTSPSWDQEIRDDVIDECNKHGGVLHIYVDKAS PQGNVYVKCPSIAAAVASVQALHGRWFAGKVITAAYVPLPNYHALFPDALRSTQLVMSSS EERDDEISPIPPQSPKKRIRRGAVSAEVYTEEDAASYVKKVVPKDYKTMAALSKAIAKNV LFAHLDDNERSDIFDAMFPVHRHAGEVIIQQGDEGDNFYVIDAGEVDIYVNNEWVILLGE GASFGELALIYGTPRAATVKAKTDVKLWGIDRDSYRRILMGSTIRKRKMYDEFLNKVAIL DSLDKWERLTVADALEPVQFEDGQEIVRQGEPGDDFYIITEGQASVLQRRAENEEPVEVG KLGVSDYFGEIALLLDRPRAATVISRGPLKCVKLDRDRFER------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------IKVSVYLQNWSHVLSYVNKAEGTPQVTEGKDSNQGVLTKLKCAAGL AELATKKYKSAAKYFLQASFDHCDFPELLSANNVAVYGALCALASFDRQELQKNVISS-- ------------------------------------------------------------ --------------------TVGALEDELMQLILDGQINARIDSHNKILYAKDIDQRSTT FEKSLTMGKDYQRRTKALILRSAMLKNQIHVKMPPREDGQGSEMSLAPGGAAS------- ------------------------------------------------------------ ---VLVNLIGQLGGCVMVLSRKKVNIACGILFGIIALQTVAYSILWDIKFLMRNLALAGG VILLLAESKAEGKSLFAGLPSLGENTPRTYMQLSGRILLVLMFLTLLRFEFSLLQMVQNL VGTALIVLIAIGYKTKLSALILVAWLTILNFYFNAWWNIPDYKPMRDFLKYDFFQTLSVV GGLLLVVALGPGGYSMDEHKKKW------------------------------------- ----------------------------------------------------------EG EYSSLEHESVPGVVECLKIITRANSQRIAKFAFDYATRHGRKKVTAVHKANIMKLGDGLF LESCREVAQHYPKIEFNDLIIDNCCMQLVSNPYQFDVMVMPNLYGNIVDNLAAGLVGGAG VVPGESFSTDVAVFEPGARHSFALGVGRDVANPTGILLCAANMLKHMHLERHGQLVQDAV ERVIKAGKVRTPDMGGYGTRSDFTIAVIKNINEDFMKFFDRSTRIMERALSESCDLFMDY SGAENEDGLAEGEKLKLNRQFFDERWSKYRTVTCIDWSTQHPELLVASYNNNEESPHDPD GVALVWNIKYKKTSPEYIFHCQSAVMSSCFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPV QRTPLSAAAHTHPVYCVNVVGTQNAHNLISVSTDGKMCSWSLDMLSQPQDSMELQHKQSK VAVTSFSFLSGDVNNFVVGSEEGAVYTACRHGSKAGISDMFEGHQGPVTGIDCQNVSGQI DFSHYFITSSFDWTVKLWNIKEPRPLYSFEDNSEYVYDARWSPIHPSLFATVDGSGRLDL WNLNNDTEVPSASVVAAALNRCRWHQGGHQIAAGDDMGKIHIYDVGEPLAVPKNDDWSKF VHTLQDLKNQQQEQEDDS----------VVEEQLDQELERLDKMDEDDYEALRQRRLKAL RKAQDQKQEWLALGHGKYEEIAEEKDFFDVCKKSKKVVCHFYR----------------- ------------------------------------------------------------ ------------------------------------KTIVLTGHGGYDKLKVEQRPKAGK GEVVVNMKAVGVNFSELLARVGMTEASAKPPCVLGYEGAGVITQLGEEVSDLQVGDRVIV LKGTWSEYVAGCVVMPDNMTFEEGAAIPVNYLTAYLMLFDMGNLRKGKSVLVHMAAGGVG IAATQLCKTVPDVTVFGTASAKHDVIRENGVTHPIDYRTQDYVQEIKNVSPNGVDIVLEP LSGEDSQKGFNLLKPMGKIIHFGVANMLSGPNKSYMQMMKTWWAVKSINPLDLMPQNKCV CGFHMGRLTALLEIVKFYSEGVVKPRVDSSWAYEDVGRAMAHMQERKNVGKVVL------ --------------------LKSGVDYRGVLACLDGYMNIALEQTEEYVNGQLKNKYGDA FIRGNNVLYISTQKRRVMAKEQAALLLARQLAELTKSPVEGFSAGLIDDDDIYRWEVLVI GPPDTYFEGGFFKAHLTFPKEYPHKPPKMKFITEIWHPNIDKTGDVCISILHEPGEDKYG YEKPEERWLPIHTVQTILLSVISMLADPNDESPANLDAAKEWRECRDEFKKKVARCVRKS QETTVRPVNTLLKESLVDFGRFVGECMPKYVQKVQVTHGDELEIMIHPDGIIPVLTFLRN HTNSQFVNITDIAGVDVPSRTNRFEIVYILMSLRYNSRIRVKTYTDELTPIQSCCSVFAG ANWYEREIWDMYGVYFSNHPDLRRILTDYGFEGHPFRKDFPVSGYVELRYDDEVKRVVAE PIELAQEFRKFDFPTPWEMFPAHKD-MKQFCQVDYRAKIWACNFCFQRNPFPPQYAAISD QHQPAELIPQFSTIEYTITRATCHPPVFLILLDTCMDEEDLQAVKESLQMSLSLLPPNAL IGLITYGKMVQVHELGCEGCSKSYVFRGSKDLSAKQIQEMLGIGRGPGQLPSNRFLQPLH KCDMALTDLLGELQRDPWPVAQGKRPLRSTGVALSIAVGLLECTYPN------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------SQFLQVFNN SPDETSYYRHMLTVEDLTQSLIMIQPILYAYSFSGPPEPVLLDTSSIQADRILLMDTFFH ILIFHGETIAQWRKSGYQELPEYENFKQLLQAPADDAQEILQTRFPMPRYIDTEANKSQA RFLLSKVNPSQTHNNMYAEAGGHVLTDDVSLQVFMDHLKKLAVSSSS------EEQMKLI SDLEIEMMADMYNRMSAACQKKCIPPKYKEADLNKGEAVCIDRCVAKYMEIHDRIGKKXT NMSQQDEETMKKLQSAQQPAVIHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYR KKVILDGEEVQIDILD-------------------FSITEQESFQATAEFREQILRVKGD DNIPFLLVGNKADLEDKRQVTIEEAQGRAGQWNVPYVETSAKTRAN-------------- -------------------GLREVVTEHLVNKVRHDVLQALHNNFLQTLNSAWNDHQTSM VMIRDILMYMDRVYVQQNNVDNVYNLGLMIFRDQVVRYPVIRDHLKQTLLDMVAKERRGE VVDRGAVKNACQMLMILGIESRTVYEEDFEKPFLEQSAEFYRMESQKFLAENSASVYIKK VEARINEEAERATHYLDKTTEEPIVKVLEEELISKHMKTIVEMENSGVVHMLKNNKTEDL GCMYKLFIRVPNGLRTMCDCISGYLREQGKALVAEEDGGKNAITFVQSLLDLKDRFDHFL HESFNDDKLFKQMISGDFEYFINLNQKSPEYLSLFIDDKLKKGVKGMTEQEIENVLDKSM VLFRFLQEKDVFERYYKQHLAKRLLLNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFKD MTVSNTTMDEFKTHVQQGTMLHGVDLFVRVLTTGFWPTQSATPKCNIPTAPRMAFEAFRR FYLGKHSGRQL------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------DRINIFPSRMAMTIMKARLK GAQKGHSLLKKKADALQLRFRMILKKIIDTKILMGDIMKEAAFSLAEAKFTTGDFNHLVL QNANKAQVKVKSKRDNVAGVSLPIFEAYTDGTDSYELTGLSRGGQQIDKLKKNYGKAVEL LVELASLQTSFV------------------------------------------------ -----------------------PLRVLVTGAAGQIAYSLLYSVAKGDVFGPNQPISLML LDIEVMLGVLKGVVMEMTDCALPLLREVVATADVTVAFKDIDVAILVGAMPRREGMERKD LLKANVKIFKTQGEALDQYAKKTVKVVVVGNPANTNSFICRKYAPSIPAENFSCLTRLDQ NRAQSQIAVRQNVKNVIIWGNHSSTQFPDVRHATVVPAAIKDDAYLKNEFINTVQKRGAA VIAARKLSSAMSAAKAICDHMHDWWFGTQQSDWVSMGIISDGYGIEPGLLYSFPVRIDHS ISIVQGLEIDTFAREKMDLTAKELLEERDAALEVC------------------------- ------------------------------------------GVPQVYYFGPCGRYNALV LELLGPSLEDLFDLCDRKFSLKTVLMIAIQLVTRMEYVHSKHLIYRDVKPENFLIGRQSN KKQHIIHIIDFGLAKEYIDPETHKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEAL GHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENYPEELATYLRYVRRLD FFETPDYDYLRKLFTDLMEKKGW------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------VLEYYSGDTDEDAFDMRKALSRDVEKKSVVP VGHPVRPEEL-------------------------------------------------- ------------------------------------------------------------ ------------------------------KIKGCWDSIHVVEVQEKSSGRSAHYKLTST AMLWLQTNKSGSGTMNLGGSLTRQVEQDANVSEASPHIVNIGRMVEDMENKIRNTLNEIY FGKTKDIVNGLRSTTALQRENLKTDLAAALRNRSQNFDDLDDVDEVLDEVENRENVDVLP ASERVDPEKRMTTAYMTKYERARVLGTRALQIAMCAPVMVELEGETDPLKIAMKELKARK IPIIIRRFLPDGSYEDWGIDELIITD---------------------------------- ------------------------------------------------SPAMMNIMMKNS WLALLGTMGAMIGSGMVCRSLPYKEGSKQLAWMVHSGIIGAVIAPLTLLGGPLMIRAACY TAGVVGGLSTLAVCAPSEKFLNMGGPLAMGLGVVFVSSIGTWFLPPTSALGAGLWSVSLY GGLVLFGMFLLYDTQKIIKRAETTPVYSVVPYDPVNNSISIYLDTINIFIRIAMILAGGG NRRR-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------TMPTKFMVGTEQGTVMSCNRKAKTPAEKIVA IYPGHHGPVYALQRNPFFPKNFLTVGDWTARIWSEDIRESSIMWTKYHRSYLTDGCWSPM RPAVFYTTKMDGTLDVW----------------------------GRLIATGSQSGTTTL LELSDGLCSLQRNEKALITVMFERETRREKILEARHREMKLKERVKSSWEDLIGNINAIA NPLASRKLTKKLYKVIKKAVRKGVREVQKCVRKGERGIVVIAGDISPIEVVCHMPAVCEE KELPYCYTPSKQDLGAACGSKRPTCMVLVREKEDYKELYDDCHSDVQGLPLPI------- ------------------------------------------------------------ -----------------------------ETEIRDFMLKKAEYYCRIGDKEGALSQFRKT GEKTVTLGYKLDMVFHLIRIGLFYMDNDLITRNLEKAQTLIDEGGDWDRRNRLKVYRGVY CMAVRDFKTAANLFLDTVATFTSYELMDYKTFVTYTVFCSMIALDRPDLREKVVRGSEIL EVLHSLPNIRQYLFSLYNCQYGDFFKALAHVEDMMKYDRLLAPHYRYYVREMRILAYSQL LESYRSLTLDYMAKAFGVRVEFIDQELSRFIAQGRLHCKIDKVGGIVETNRPDSKNWQYQ STIKQGDILLNRVQKLSRVINI-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------HSPLMSVTNAISGITA VGGLLLMGGGYFPTNTVQVLAATAAFISSINIGGGFLVTQRMLDMFRRPDDPPEYNKLYA IPALAFLGAYGASLTGNFPDMHQMAYLAASLCCVGALTGLSSQKTCRVGNALGIIGVTTG IAATLGLLNPQPAVLAQMAGAMGLGGTLGTVMAKRLEVTDLPQMVALFHSLVGAAAVITC VANYMAEFDSFATDPAANVTKTALFLGTYIGGVTFTGSLVAFGKLQGMLKSDPLLLPGRH PMNLALLLGNVGALIYYMASPENVGMGMLGTTSLLSSIMGVTLTMAIGGADMPVVITVLN SYSGWALCAEGFMLNNNLMTIVGALIGSSGAILSYIMCKAMNRSLPNVILGGYGTSSTGT GKPMEITGTHTEINADQTVDLITEANNIMIVPGYGLCVAKAQYPIAELVELLKKKGKNVR FGVHPVAGRMPGQLNVLLAEAGVPYDIVHEMDEINDDMPDVDLTLVIGANDTVNSAAEED PNSIIAGMPVIRVWLSGQVVVMKRTLGVGYAAVDNPIFFKENSSMLLGDAKKTCDALLSR TK---------------YLGGVDQILVHQTVSLVEAFTSIECACKFQVKNSVGQQIFFAA EESDFCSRQCCGGHRGFIMHMADNFGNMVMRATREFKLCGGWC----------------- -----------------------------------------------CGQIRKQWTGFVK EVFTDADNFGITFPMDLDVNIKAVMMGAIFLIDFMFFEKEQN--DPELQEFLAVEQQKAM FQNQIHRLTDMCWDLCVDKPKDKLDGRTEGCLGNCVERFLDTTHLITGRFQQLLQKGM-S RSGGLKQRRTVTQEEEDHDSKETRLTLMEEVLLLGLKDREGYTSFWNDCISSGLRGCILI ELALRGRVELEKTGMRRRSLLNRKVICKSDAPTGDVLLDEALKHVKETQPPETVQSWVEY LSGETWNPLKLKYQLRNVRERLAKNLVEKGVCTTEKQNFLLFDMTTHPLTDNTIKQKLVK RVQDSVLSRWVNDPHRMDKRLLSLIYLAHASDVLENAFAPLNDDDYEVAMKRVRELLDLD FEQEGMKEGINETMWCVIAAFTK------------------------------------- ------------------------------------------------DEQICDLKYEKT FDFATLDLKKLKVKDLKQILSDWNEQCRGCTEKSDYVALIEELIPKYAPEAA-------- -------------------------------------------------------MEKFR LEQKVLFKGKCLEEWYFEFGFVIPDSTNTWQSIIEAAPESQMMPANVLNGNVVIETKFFD GDMHVSTSKVRIFYVMPKVVSRSVVCTDTKDQEEYQGEKPLYVYYCLCGQMSLILDCPME KLPMRRRDNARVIDSAKHAHKITCEPDETVYLKR-------------------------- ---------------KKDVYSLIQEPKKVMVTKHTKNMGKFSSVTVSTVDEEEEEIEAKE IADSYAANAKVIEKQLLRRGMSKRKLLEQAEEEAKRMRPKGTLID-------------RR GYADMAFTFASPASVKVKQIDVPSFSGSFGILPEHVPLLAVLKPGVMTVHEEDGTPQKYF VSSGSVTINDDSSVQILAEEAAKISDLDPQAIRDGAAKAAQDAGSDQAKAEAQIALECYE SLQKALE-----------------------------KKKRFKFITSELRLTEALHEPHIC EKILEYNVHAERKGSLRYAKGQSETMSTLHGLVNKGVKVELGMPYEMWDQPSAEVSKMQR YCFSLAEQYEDDIENWYYNNQLNLAKYICQDRYLKHKN-LFTPTDVTSEDDVKAALLTKE KFGRLDVAVNCAGVGFAIMTYNKNKDRVHDLAPF-------------------------- ------------------------------------------------------TIAPGL FDTPLLASLPEEVRTFLSSTIPFPGRLGNPDEFAHLVQSIVENPVLNGETIRLDGALR-- -------GRNSNVKEKLSRDYPVVDHTYDAIVVGAGGAGLRAAFGLAKEGFKTACITKLF PTRSHTVAAQGGINAALGNVEEDRWEYHFFDTVKGSDWLGDQDAIQYMCEEAPKAVIELE NIGMPFSRLESGKIYQRAFGGQSLDYGQGGQAHRACCVADRTGHSMLHTLYGRSLHYDTD YFLEYFALDLLMEGGKCNGVIALSMEDGNIHRFRANNTVLATGGYGRSYFSCTGAHTCTG DGTAMLSRANLPNEDMEFVQFHPTGIYGAGCLITEGCRGEGGYLLNSEGERFMERYAPTA KDLASRDVVSRSMTIEIREGRGVGPEKDHAFLQLSHLPPEQLNERLPGISETAMIFAGVD VTRDPVPVLPTVHYNMGGVPTNYNGQAIECNGKDVIIEGLYAAGEAACVSVHGANRLGAN SLLDLVVFGRACALHIADTCKPGDPAREINQNAGEASVSNLDKLRFAQGTTPTSELRLKM QKAMQTNAAVFRDGDTLKEGCEKLDKLWEEMNIKVTDQGMVWNSDLVETLELQNLMINSM QTVYAAENRKESRGAHAREDFPDRIDEYDYSKSLDGQQKKPFDQHWRKHSMSYVN-EKGQ VTLEYRPVVDSVLDDTKIQTIPPKMRVY-------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------GGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHD HPDVATMLNILALVYRDQGKYKEAANLLNDALGIREKTLGPDHPAVAATLNNLAVLYGKR GKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEKYYKRALEIYL KTLGPDDPNVAKTKNNLASAYLKQGKYKQ------------------------------E SLKDGTYLCKLANIL------VKFNTSKLAFKQMENISQFLSFCERYGLAKTDLFQTVDL YEKQNMWNVVLTIFALGRKAQANGFDGPVLGPRESTKNVREFSDEQLKAGKLQMGSNKGA SQAMGTQRFINDIKVADISKEGQGIIGLQSGNKGASQAGMQFGGQRHINDIKVDDMSKEG QNIIGLQSGTNAGASQAGQNFGKPRDIADIRSDGFDREGQSVIGLQAGSNQGATQSGMTF GGVR-------------------------------------------------------- ----------------------------------------------------------MP DVQRFGYDPIACFAWNKDRSQVALPNNHEVFIYKYRWDKTDTLDEHVQRVTGIDWAVNSN RIVTCGADRNAYVWPTLVILRINRAATCVKWSPLENKFAVGSGARLISVCYFEQENDWWV SKHIKKPLRSTVTSLDWHPNNILVACGSTDFRARVFSAYIKEVEEKPASTAWGNKMTFGK EMASFSSGGGWVHSVSFSASGDRLAWVGHDATVTVVNATIRTQYLPFLTCTWVTENSLVA AGHDCCPMLFSYDAQNVTFVAKLDETKHTAMGMFQQLDKRAQTLTTIHQNTITGLQLHSG GKSGALKFTTCGIDGQIITWDLK------------------------------------- ------------------------------------------------------------ ------------------------------------------------HGLKPLDVEFMK RLHDKVNIIPLLAKADTLTPDECREFKXTVLNEIAQHKIKIYEFDDDEETKLQKKLKDRV PFAVVGSNTVVDSQGRKVRGRIYPWGVVEVENLEHNDFIALRNMLIRTHMQDLKDVTNNV HYENFRFNKLAAVTKNPLAQMEEEKKEHVQKMKKMEAEMEQVFEMKVREKKQKLKDSESD LQKRAEQMKKSLEQQAKELDEARKRFEKERMAWEESQEMARRYDSRTTIFSPEGRLYQVE YAMEAIGHAGTCLGILASDGVVLCAEKRNTNKLLDEVSYSEKIYKLNDDLACSVAGITSD ANVLTNELRLIAQRYMLQYQEPIPSEQLVSTLCDIKQAYTQFGGKRPFGVSLLYMGWDRH YGFQLYQSDPSGNYGGWKATCIGNNSPAAVSMLKQEYKEGETDLKAALDLAVKVLSKTLD TNKLTNEKVEMATLTRSEGKTAIRILPASELDVIIKKFEEEEAKLEAEKKK--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------EHRTEIDARAGTFQAFEMFGHQLLQNNHYASDDVRSKLNDLAEAREELEKAWIA RRAKLDQCLELQLYNRDCEQAETWMAAREASLRDETDGADNVESLIKKHEDFDRAIAAQQ EKIAALEAHADQLINQEHYDSDGIEDRKRQVLERWARLKEALLENRAKLGEAQSLQQFSR DADEIEIWITEKLQMAMDESYKDPANIQSKHQKHQAFEAELAANSDRLGTVVNMGQKLID NQKCSGSEGAVEERIMKMAKEWEYLTTKSTEKSEKLKEANRQRMYTAAVKDLEFWLGEVE HMLETEDYGKDLATVQNLVKKHQLLDADVRAHEDRVRDLNDQAEAFIDSGMWDTDSIREK KQSINERYERVRTLAAHRRTRLDEANTLHQFFRDIDDEEAWIKEKKLLVGSEDYGRDLTG VQNLRKKHKRLEAELSSHEPTIQAVQDTGEKLMSESNLMTDDIRQRLSTLGDNWDELKHL ASQRGQRLDESLAYQQFVANVEEEEAWILEKQHLLGGDDYGDTLAAVQGLLKKHDAFETD FQVHRGRCDEISKEGNKLIEEGNYNHELIAQKVSTLQEKLGSLQQDANTRKSRLIDNSAF LQFIWKTDVVESWIADKETQIRSDDYGRDLSSVQTLLTKQETFDAGLQAFEKEGIQTITA LKDQLVAAHHAQTPAIESRYADVISRWQRLLADSDARKQRLLRLQEQYRQVEDLYLTFAK KASAFNSWFENAEEDLTDPVRCNSVEEIKALREAHDQFKASLSAAEADFNQLAALDKEIK TFNVGPNPYTWFTMEALDDTWRNLQKIIKERDDELAREQQRQEENDLLRKQFAQTANAFH QWLTDT-SAMMEGTGTLEAQLEATKRKSVEVRNQRAQLKKIEDLGAAMEERLILDNRYTE HSTVGLAQQWDQLDQLGMRMQHNLEQQIQACNTSGVSEEALREFSMMFKHFDKEKTGRLD HHNFKSCLRALGYDLPMVEEGQRDPEFETILDIVDPNRDGFVSLQEYMAFMISRETENVQ SSRDVEAAFRALTSGDKPYITAQELYANLTREQADYCVARMRPYEDPKSRSIPDAYDYVN FTTELFIN-MMCYQCDSNEDKSCPANKRFDWRINSMIDCNSLEAHTPGKFCMKITQQSPG WRGWTKVTRRCGTRS--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------LTIVDYDMVHYHPSEVAAASLCLSMKVLD WCDTLNHYSNYSEKDLMPILQKIAQLVSKKLTAIKTKYTSSKF----------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------LLGPQKREQWLQLRSEIEAMTDNWLT LALKSLSIINSRSSCVNVLVTTTQLVPALAKVLLYGLGGVFNIENIYSATKIGKESCFER IVSRFGRKCTYVVVGDGRDEEAAAKQMNWPFWRISNHSDLAALHHALDLGYLASALSVGG DRTTGQSIRTQNVMAACSIANIVKSSLGPVGLDKMLVDDVGDVTITNDGATILKLLEVEH PAAKVLVELAELQDQEVGDGTTSVVIVAAELLKNADELVKCKIHPTSIISGYRLACKEAC KYIQEHLTINTDDLGRECIVNAAKTSMSSKIIGPDSEFFSNMVVDAANAIKTSDGKGGSR YPIKAVNVLKAHGRSTRESILVHGYALNCTLASQAMTKKITNPKIACLDFGLMKAKMKMG IQVLVEDPEKLEDIRKRESDITKERIQKILATGANVILTTGGIDDLCLKYFVEAGAMAVR RCKKQDLKRIAKATGGQLVVTMVNLEGEETFDASFLGTADEVALERICDDELIFIKGPKA RSAASIILRGANDFMVDEMERSIHDALCVVKRVLESKSLVPGGGAVEAALSIYLENFATT LSSREQLAIAEFARSLLVIPKQLGVNAAQDSTDLVAKLRAYHNTSQTKAEHQDLKWIGLD LTNGVVRDNKKAGVFEPAVSKIKSLKFATEAAITILRIDDMIKLTPEDKGRSGYADALRA GMLEDIEARLLASKNILNQLLVEGKDLTVEYQIFNVGGSAALDVQLVDDSFPDGDFELVR GFLRVKWQRIAPGTNVSHVVILRPLKSGYFNFTAAEVSYMPTEDDYQYGYSSAPGEGGIL NFRDYDRKFSPHVLDWGAFAIMTLPSLGIPFLLWHSSKAKYESNKAKKN----------- ----------------ALVNENVSLVISRQILSDFTAQLPNLPDAAALDVSHYTLEKVQP RVISFEEQVASIRQNLARLFEKDQNWREAANVLVGIPLETAQKQYTSDYKLDTYLKIARL YLEDEDPVQAEAYINRASMLWANTKNEELQVYYKVCYARVLDYRRKFIEAAGRYNELSYR PIVAEEERMEALKNALICTILASAGQQRSRMLATLFKDERCQRLPAYGILEKMYLDRIIH SSDLQEFSAMLQPHQKAVTSDGSTILDRAVIEHNLLSASKLYNNISFDELGRLLEIAPGK AEKIASQMITEGRMNGYIDQIDSIVHFEAREALPSWDKQIQSLCLQVNNIIEKISQHSPE WIAKAMET---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXX---------EKNNVGFVQLNRPKALNALCDGLMVEL NQVMADFDKDPEIGCIVLTGSERAFAAGADIKEMQPWEFPATYTENFLGHWTGLTKTQKP IIAAVNGFALGGGCELSMMCDIIYAGEKAQFGQPEITLGTIPGAGGTQRLTRAVGKSKTM EMVLTANRISAAEAEKAGLVSKVFPPDQVVDEAVRTAEKIAGFSKVAVQMAKESVNASYE LTLSEGIRLERRFFHQTFGTNDRREGMTAFSEKRPPNFTD >Megalomma_vesiculosum MSERKAVIKNADMAEDMQQDAVDCATTALEKYNIEKDISAYIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX- ----------------------------------------------------MPTKILRI TTRKTPCGEGSKTWDRNQTK-----------------------------------MDQVM QLVEPAKQFSKDSIRLVKRCTKPDRKEFQKIAMATAIGFALMGFIGYFVKLIHIPINNII VMAAQISKKRKFVADGVFRAELNEFFTRELAEDGYSGVEVRVTPTRTEIIILATRTQSVL GEKGRRIRELTAVVQKRFNFPEGTVELYAEKVATRGLCAIAQAESLRYKLIGSLPVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPCNDYIDTAVRHVLLRQ GVLGIKVKIMLPWDPTGKLGPKRPLPDHVSIVEPKEEVPITSPYSENKDTK--------- ------------------------------------------------------TVKKGK PELRKKVMPAVVVRQRKAIHRKNGVFIYF------------------------------- ------------------------------------------------------------ ----------------------------------------------RTKTPGPGAQSALR ALARSGMKIGR------------------------------------------------- ------------------------------------------------------------ --------------IVAGFGRKGHAVGDIPGVRFKVVKV------------------XXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---- ------------------------------------------------------------ ---------------------------------------FLERRLQTQVFKLGLAKSIHH ARVLIRQRHIRVRKQVVNIPSYMVRLDSQKHIDFSLKSP--------------------- --MGNVFASLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVGEAREELMRMLAEDELRD AVLLVFANKQDLPNAMNAAEITDKLGLHSLRNRNWYIQATCATSGDGLYEGLDWLSNQLK NQK-----------------QCKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLC- ------------------------------------------------------------ -------LMKHGYIGEFEIIDDHRAGKIIVHLNGRLNK---------------------- ------------------------------------------------------------ -----------------------------------------------------------D IPEDLYHLIKKAVAIRKHLERNRK------------------------------------ -------------------KWSSEDVQVSDISLTDYVACKEKYSKYLPHSAGRYQVKRFR KAMCPIVERLTSSLMMHGRNNGKKLMAVRIVKHAFEIIHLLTGEN--------------- -------------RQAVDVSPLRRVNQAIWLLCTGAREAAFRNIKT-------------- --------------------------MTLRGTLQGHNGWITQIATTPHNPNMLLSASRDK TLISWELNRDQNYGVPDKRMTGHGHFISDVVMSSDGQFALSGSWDNTLRLWDLATGQTTR RFVGHTKDVLSVAFSADNRQIVSASRDKTIKLWNTLGVCKYTIEDGHTEWCSCVRFSPNT NNPIIVSAGWDKIVKVWNLTNCKLKTNHFGHLGYLNCVTVSPDGSLCASGGKDGQAMLWD LNEGKHLYTLDGG----------------------------------------------- -----------------------------------MIEYKLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKVVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKLSRQWNCAFLETSAKSK VNVGEIFYDLVRQINRKNPDP--EQKK-ETEHINLKVTGQDGSVVHFKIKRNTPLRKLMS AYCERTGVRMDSMRFRFDGNPINETDNPSGLDMEDGDSIDVFQQQTGGMSALPMNPKPFL NGLTGKPVMVKLKWGMEYKGYLVSVDGYMNLQLANTEEYIDGAISGNLGEVLIRCNNVLY IRGVEDDDEEGEMRE----------------------TALQEVLKTALINDGLARGLHEC AKAL------------------------------------------------LCKIDKEG KARKVVGCSSVVVR--------------------MASIRKKLVIVGDGACGKTCLLIVFS KDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSI DSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDENTKRELMKMKQEPVRTEEGRA MAEKISAFSYLECSAKTKEGVREVFEMATRAALQTRKKKKGKMDDFQSAEETAFVVDEVS NIIKESIEGAIGGNAYQHNKVNQWTSNVVEQCLNQLTKLNKPFKYIVTCVIMQKNGAGLH TASSCFWDNSTDGSCTVRWENKTMYCIVSVFGLAIXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------ ------------------------------------------------------------ ----LKIMPRDSHLDNGQRTRFKAFVAIGDYNGHIGLGVK-------------------- ------------------------------MRLIPAPRGTGIVSAPVPKKLLNMA----- -----------------------------------------------------MSGGIDV LGLKEDDVQKFLACSTHLGSTNVDFQMEQYTFKRKPDGVYIINLRKTWEKLLLAARAIAA IENPADVCVISARP---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------MKFNTLVSSSRRKNRKRHFTAPSNVIRKIMSSPLSKELRAKYLVRSIPIRKD- ------------------------------------------------------------ --------------------------SSTSVGGQVRQRKTASAGGSAAGMWRFYTEDSPG IKVGPVPVLVMSLLFIASVFMLHIWGKYTRG----------------------------- ---------------FAEKMMGTVDVRVDTRLNKHVWSCGVRNVPYRVRVRQSHK----- ----------------------------ASKSEFLVNGKYRLVRKIGSGSFGDIYLGINI SSGEEVAVKLESHKARHPQLLYESKLYKILQGGVGIPHIRWYGEKDYNVLVMDLLGPSLE DLFNFCGRRFTMKTVLMLADQMIGRIEYVHNKNFIHRDIKPDNFLMGIGRHCNKVFLIDF GLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRGS LPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGYPAEFAMYLNYCRGLRFEEAPDYMYLR QLFRILFRTLNHQYDYVFDWTILKQKAATAMNAEKLKLRIGGKGTARRKKKVVHRTATTD DKKLQSTLKKLGVNTIPGIEEVNFIKEDGQVIHFNNPKVQASLGANTFAVTGHAENKQIT EMLPGILNQLGAESLANLKKLATTTAEIDEDDDEVPDLVENFDEASKGEMVRYSLDPENA AKSAKARGSHLRVHFKNTHETAHRIRGMHLRRAVAFLKNVCQKKECVPFVRYNGGIGRCA QAKNWNASQGRWPKKSAEFLLQLLRNAESNAEFKGLDMDHLVIEHIQVNRAPKMRRRTYR AHGRINPYMSSPCHIEVILAEREQAIAKPAPKKVSQKKLKRQKMMMREKKTGPKPELSEE QKQEIREAFDLFDADGSGTIDAKELKVAMRALGFEPRKEDIKKMISEIDKEGSGTIDFND FLTMMTQKMAEKDSKEEILKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQEADRN GDGEIDEQEFLRIMKKTSLYMGISRDKWHKRRSTGGRMVPLRKKRKFEMGRPAANTKLAA QRIHTVRTRGGNKKYRALRLDHGNYSWGSESISRKTRIISVEYNASNNELVRTQTLVKNC IVRIDA-----------------KKGAKLTEVEEAVLTKRSKKTQLKYDERRKISKVELA LEEQFASGKILACVSSRPGQCGRCDGYILEGKELEFYQRKLKSK----SLVVPEKFQHIL RVMNTNIDGRRKI----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------SKAKQSRSEKKA RKAICKLGLKQVTGVSRVTIRKSKNILFVINRPDVYKSPASDTYIVFGEAKIEDMTQTAT AAAAEKFKADEEIDETGIEAKDIELVMSQANVTRSRAVKALKNNSNDIVNAIM------- -------------------------------------------AGFVTHLMKRIQRAPVR GISIKLQEEERERRDNYV-------------------------------------MKWEY KEEHPFEKRRAEGEKIRKKYPDRVPVIVEKAPKARVGDLDKKKYLVPSDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGALYQEHHEEDFFLYIAYSDESVYG--------- ------------------------------------VRSFGIRRNEKIAVHCTVRGAKAE EIL--------------------------------------------------------- IAHRRKRLSKIGCEHKVKKEESMKWFQQ----------MGIKFLEFVKPFCAILPEVAKP ERKIQFREKVLWTAITLFLFLVCCQIPLFGIMSSDSADPFYWMRVIMASNRGTLMELGIS PIVTSGLIMQLLAGAKIIEVGDSPKERALFNGAQKLFGMVITVGQAIVYVMTGMYGEPAE LGAGVCLIIILQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIMWKAFSPATVN TGRGTEFEGAIIALFHLLATRQDKVRGLREAFYRQNLPNLMNLLATVLIFAVVIYFQGFR VDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAAKFSGNFLVNILG TWADVGGGGPARSYPIGGLCYYLSPPETLGHVLVDPIHAVLYIIFMLGSCAFFSKTWIEV SGSSAKDVAKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFMGAIG SGTGILLAVTIIYQYFEIFVKEQSEMGGMSTLLF-------------------------- -------------------------------------------------VRRDYLHYIRK YNRFEKRHKNVSAHLSPCF----------------------------------------- MVNVPKARKTFCKGTKCRKHTLHKVSQYKKGKESLAHQGKRRYDRKQSGYGGQTKVIFRK KAKTTKKITLKMECTECKYKKLLCIKRCKHFELGGDKKKKGQMIQF-------------- ------------------------------------------------------------ -----------------------------------------------------------A TVISHNPDTKRSRVKLPSGSKKVIP----------------------------------- ------------------------------------------------------------ -------------------------------TQHGKYTCSFCGKENMKRRCVGIWACKSC K------------------------------MGRRPARCYRYCKNKPYPKSRFCRGVPDS KIRIYDLGRKKARVDDFPLCIHMVSDEFEQLSSEALEAARICANKYLVKHCGKEAFHMRV RVHPFHIVRINKMLSCAGADRLQTGMRGA------------------------------- ------------------------------------------------------------ ----KVLKILGRTGSQGQ------------------------------------------ ------------------------------------------------NWSEKAKRRRTQ GVGRMRHMKKVFRKFRNGF-----------MLDDRASAKELDQWVEQLMECKQLTENQVK TLCEKAKEILAKESNVQEVKCPVTVCGDVHGQFHDLMELFKIGGRSPDTNYLFMGDYVDR GYYSVETVTLLVTLKVRFKDRITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHTNGLTLISRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRC GNQAAIMELDDALKYSFLQFDPAPRRGEPHVTRRTPDYFL-------------------- ------------------------------------------------------------ --------------------VAEERAGRKCGGLRVLNSYWVAQDSTYKFFEIIMVDPFHK AIRRDPKINWLCKPVMKHREMRGLTSAGKSSRGLGKGHLFTKTIGGSRRKNWKNNNTISL RRKRGIALGRLAEERKSWRKDHPFGFVARPTKNLDGSLNLMNWECAIPGKKGTAWDNGLF KIRMLFKDDYPSTPPKCKFEPPLFHPNVYPSGTVCLSLLDEDKDWRPAVTIKQILLGIQE LLNEPNIKDPAQAEAYTIYCQNRVEYERRVREQAIKFKDPSLGKSSKMLQHINFRMRCTL QDGRTFVGTFKAFDKHMNLILGDCDEFRRVRQKKGDKREEKRVLGLVLLRGENLVSMTVE GPPPAEEGMARVPLGAAQGGPGQGRSAGRGVPAQGGLQGPVRGVGGPSPQQMQP-PGMGR G---ENMPTFKLVLVGDGGVGKTTFVKRHLTGEFEKKYIATLGVEVHPLVFHTNRGPIRF NVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTARITYKNVPNWHRDLVRVCENIPIVLCG NKVDIKDRKVKAKAIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLVGDPNLEFVAMPA LLPPEVNMDPSMAAQYEQELESAANTALPDEDEDLNEGIRQYYVSKIEELQLVVTDKTQN LRRLEAQRNELNAKVRMLREELQLLQEQGSYVGEVVKAMDKKKVLVKVHPEGKFVVDLDK NIDINDVTANSRVALRNDSYTLHKILPSKVDPLVSLMMVEKVPDSTYDMVGGLDKQIKEI KEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ KFIGEGARMVRELFVMAREHAPSIIFMDEVDSIGSTRLESGSGGDSEVQRTMLELLNQLD GFEPKQNIKVIMATNRIDILDSALLRPGRIDRKIEFPAPNEEARLDILKIHSRKMNLTRG INLRKCAEMMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFELAVAKIMQKDSEKNMSI KKLWKLTFAENFGLSGAAAIISKTAAAPIERVKLLVQNQDEMLKTGRLDRPYSGVMDCTL RTFRTEGVLPFWRGNLANCIRYFPTQALNFAFKDQIKLIFKQKKSDPYMVNFGKNIASGG VAGAMSLCFVYSLDYARTRLANDAKSAGK------------------------------- ------------------------------------------------------------ ---------------------------AGANILRGVAGAGVLAGFDKFKELYIAFREMGD KSDLDRQIEELRRCEVIKESEVKALCSKAKEILVEESNVQQVSSPVTVCGDIHGQFYDLK ELFKIGGHIPETNYLFLGDFVDRGYYSVETFLLLLALKVRYPDRITLIRGNHESRQTTQV YGFYDECLRKYGSVSVWKYCTEVFDYLCLAAVIDHKVFAVHGGLSPSIHTIDQIRVIDRL QELPCDGPMSDLLWSDPEDIQGWSMSPRGAGFQFGADIVQQFNMANSLELICRAHQLAME GYKYHFDEAVVTVWSAPNYCYRCGNVAAILELDEHLKRHFSIFEAAPQEERGRKTPDYFL VRLPPEVNRILYVKNLPYKITAEEMYDIFGKYGAIRQIRVGNTPETRGTAFVVYEDIFDA KNACDHLSGFNVCNRYLVVLYYQPNKSFKKTDLDKKAQDLDNMKAKYGLSTPDM-MSIGV PIKVLHEAEGHIVSLETTTGEVYRGKLIEAEDNMNCQMSTITVTYRDGRVAQLENVFIRG SKIRFLILPDMLKNAPMFKRVGAGRGKSAILSRAARGRGRGGPG--RGGMQNEAGEYVDM YIPRKCSASNRIIAAKDHASIQVNIAEVDETTGRMTGQYKTYAICGQIRRMGESDDCINR LAKKDNLI--MARGPKKHLKRLNAPKHWMLDKLGGVFAPRPSQGPHKLRECLPLVVFLRN RLKYALTYDEVKKIVN-------------------------------------------- ----------------------------VTTHDGRTIRYPDPIVKVN-----MGTKDDEY DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSILVDGKVIKAQIWDTA GQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADNNIVIMLVGNKSDL RHLRAVPTDEAKAFAEKNNLSFIETSALDSTNVETAFQQILTEIYKIVSQKQIRDSPDDN NVQTIHVAPTDNSMDRKSKCCSMSSRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVR GKDVVVLGVEKKAVAKLQEDRTVRKIALLDDHVALAFAGLTADARILINRARIECQSHKL TVEDPVTLEYITRYIATLKQKYTQSNGRRPFGLSTLIMGFDGTARLYQTDPSGTYHEWKA NAIGRSAKTVREFLEKHFEEDSISEHDTIKLALKALMEVVQSGSKNMEVAIMRRGEKLKM LENEDIEKVIKEIEKEKEEEAEKKKQKGGAGGGDKKDDKDKKRKYEPPIPTRVGKRKKRI KGPDAASKLPQVTPHTKCRLRLLKSLRIKDYLLMEEEFIKNQERLKPQEEKQEEERSKVD DLRGTPMSVGSLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDQLEPGCSVLLNHKVHAVV GVLGDDTDPMVTVMKLEKAPQETYADIGGLDTQIQEIKESVELPLTHPELYEEMGIKPPK GVILYGEPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPS IVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPA LIRPGRIDRKIEFPLPDEKTKRRIFNIHTSRMTMADDVNLEDYIMAKDDISGADIKAICT EAGLLALRERRMKVGNEDFKKAKENVLYRKNEGHPEGLYLKRKPYSPFQNSSNVEYALAR VDDLVNAARKDSVWPMTFGLACCAVEMMHFAAPRYDMDRFGVVFRASPRQADCIIVAGTV TNKMAPALRKVYDQMPDPRWVISMGSCANGGGYYHYSYSVLRGCDRVIPVDIYVPGCPPS AEALLYAVLQLQKKIKRMKIMQMWYRKTEFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYA NNSNYKNDTMIRKEAFVHKSVMEELKRIIEDSEVMQEDDAAWPPPDRVGRQELEIVIGDE HISFTTSKVGSLVDVNQSKDPEGLRTFYYLVQDLKCLVFSLIGLHFKIKPIXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------ -----------------------------GETCLLDILDTAGQEEYSAMRDQYMRTGEGF LCVFAVNNTKSFEDINQYREQIKRVKDADEVPMVFVGNKVDLQSRTVETKDGKNLADSYS IPYVETSAKTRQGVDDAFYTLVREIRKYMGDRYNIHSQLEHLQSKYIGTGHADTNKWEWM TNQHRDSFSSYVGHFDMLNYFSVVENETKARVKFNLMERMLQPCGPPPERPDEMKIELCQ FSGYKIYPGHGKRYVTKD------------------------------------------ ------------------------------------------------------------ ---MKLNISYPATGCQKLIEVDDEKKLRPFYEKRISTEIGADSLGDEWKGYVVRIAGGND KQGFPMKQGVLTHLRVKLLLSKGHSCYRPRRSGERRRKSVRGCIVDSNLSVLALVIVRKG EQEIPGLTDSTIPRRLGPKRASKIRKLFNLSKEDDVRQYVVRRPLAPRSKAPKIQRLITP VVLQRKRHRLALKKQRSMKKREDAAEYAKLLAQRMKEAKERKAERRRSASHSKKVKAKDL RGKKKEDLLRQLDELKTELGSLRVAKVTGGAASKLSKIHTVRKSIARVLTVI-------- -----PKDLRKKKTRAIRRNLTRFE-----------------------AKDESTLVTKKV YFDIHIGGESAGKIVIGLFGKTVPKTVDNFAALASGE-GYKDSIFHRVIKDFMIQGGDFT NFDGTGGKSIYFKDENFNLKHYGPGWLSMANAGKDTNGSQFFITTVKTTWLDGRHVVFGK VLEGMDVVRKIEGSKTSGDKPMKECKIVDSGIQEVTEPFVVSKE---------------- --------------------------------KSKVVVQADIPLSKRYLKYLTKKYLKKH NLRDWLRVVSSEKDTYELRYFQINDNEDEDEADENKEEKGDDDLKYGGCEGPDAMYVKLV SSDGHEFIVKREHALTSGTIKAMLSGPGQFAENETNEINFREIPSHVLQKVCMYFTYKVR YTNSSTEIPEFPIAPEIALELLMAANFLDCKKIITLEELRQHKDAKSLWIAIHDKVYDIT KFLDEHPGGEEVLLEQGGAYGTEAFEDVGHSTDARELMEGYQIGDLAEEDR--------- --------------MSYMLQHLHNGWQVDQAILSEEDRVVVIRFGHDWDPACMVMDETLY RCAEKMKNFAIIYLVDISEVPDFNKMYELYDPCTVMFFYRNKHIMIDLGTGNNNKINWCM EDEQEFIDIVETVYRGARKGRGLVVSPKDYSTKYRYKKLQRQLEFLEVQEEYIKDEQKNL KKEYLHAQEEVKRIQSVPLVIGQFLEAVDQNTGIVGSTTGSNYYVRILSTIDRELLKPSA SVALHKHSNALVDVLPPEADSSITMLQSDEKPDVAYADIGGYDIQKQEVREAVELPLTHF ELYKQIGIDPPRGVLMFGPPGCGKTMLAKAVAHHTTASFIRVVGSEFVQKYLGEGPRMVR DVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVI MATNRADTLDPALLRPGRLDRKIEFPIPDRRQKRLIFTTITSKMNLSEDVDLEDYVARPD KISGADINAICQEAGMQAVRENRYVVLPKDFEKGYKNNIKKDEQEHEFYK---------- ----------------EKLTLESNFINDLGLDSLDHVEVIMAMEDEFGFEIPDGDAERLL TPADIVQYVADKEDVSRRVQAMSEDLKNVEFETSEEVDVTPTFDSMGIREDLLRGIYAYG FEKPSAIQQRAIKPVVKGRDVIAQAQSGTGKTATYSISILQGLDTQVRETQALVLSPTRE LAVQVQKVLLALGDYMSVQCHACIGGTNVGEDIRKLDYGQHVVSGTPGRVFDMIRRRNLR TRSIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLVSATLPHEILEMTSKFMTDPI RILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTRRKVEWLTEKM IEANFTVSSMHGGMEQKERDAIMKEFRSGASRVLISTDVWARGLDVQQVSLVINYDLPNN RELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLILSMRRP FDPAAHELDANFRLTRFADLKGGCKVPQEVLLKLLEGL-QGQESEQAQFQYVAAAPKIGI GMDSCVTPLRHGGLSLVQTTDFFYPLVDDPYMQGKIAAANVLSDLYAMGVTECDNMLMLL ACSQKMSEKERDVVVPLVIRGFRDTAEEAGTSVNGGQTVVNPWMTVGGVATTVCQPNEFI MPDSAVVGDVLVLTKPLGTQVAVNAYQWLDQPERWNRIKLVVGEDDVRKAYQRAMFSMAR LNRTGARLMHKYNAHGATDVTGFGLLGHAQNLARIQKNEVGFVIHNLPIIAKMAAVSKAC GNMFGLLQGQSAETSGGLLIALPREQAAAFCKDIEKQEGYQAWIIGIVEKGTRSARIIDK PRVIEVPAKEKDFIISCLDTIYGYFVTVDAHAEECFFDKVTSGTKMSLMFEVAEGGFLDI DVKIRGPDGKNIYSGERESNGKYTFAAHMDGVY--------------------------- --------------------QHEQAFMKVRSNLHITINDNTNSRVVLWSFFEALVLVAMT LGQIYYLKRFFEVRRVVMAATLKPYLTAVRHTLTAAMCLENFPSQVIERHNKPEVEVRTS KELLLTPVVISRNEKEKVLIEGSVNSLRISIAVKQADEIEKILCHKFMRFMMMRAENFII LRRKPIEGYDISFLVTNFHTEQMYKHKLVDFIIHFMEEIDKEISEMKLAVNSRARISAEE FLKQFSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLV TMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTMPNTFKTLDSWRDEFLIQASPRDPEN FPFVVIGNKIDLENRVVTTKRAQQWCQAKGDIPYFETSAKEAINVEQAFQTVAKNALAQE TEVELYNEFPDQIKLSNDQNDTGCACTAPFDARFPNQRQVRSCWQNYVDYHRCIKIEDWE PCQYFRNCYKALCPAKNVEKWNGQIEEGSFAGRI-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------PPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGI DPPKGVLLYGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMART KKACIIFFDEIDAVGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDT LDPALCRPGRLDRKVEFNLPELEGRSHIFKIHAKSMSVEKDIRYELLARLCPNSTGAEIR SVCTEAGMFAIRARRKMATEKDFLEAVNKVIKAYAKFSATPRYMTYN------------- -----------------------KTIEKFEKEAQEMGKGSFKYAWVLDS----------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------EYAPLGRFAVRDMRQTVAVGVIK---- ---------------ELEQLRQEAEQLKNQIREARKAAADTTLAQAAANVEPVGRIQMRT RRTLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDGFTANKVHAIPLRSSWVMTCAYAP SGSYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIVTSSGDMTCA LWDIETGQQTTSFTGHTGDVMSLSLSPDMRTFVSGACDASAKLWDIRDGMCKQTFSGHES DINAITFFPNGFAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLG GYDDFNCNVWDTLKQDRAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKIWNMSYAYLF KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQEA FRSITRSYYRGAAGALLVYDITRRDTFNHLTSWLEDARQHASSNMVIMLIGNKSDLEARR DVKKEEGEAFAREHGLIFMETSAKTAANVEEAFINTAKEIYQKIQDGVFDINNEANGIKI GPQHSPSSRSGGSGGNQGGG-KMGRIELGDITHHNIKQLKRLNQVVFPVTYNDKFYKDVL EVGELAKLAYFNDIVVGAVCCREDKSDGQRRLYIMTLGCLAPYRRLGIGTTMLKHVLTLC KQDGKFDNIYLHVQINNDSAIKFYEMHGFKIVEKKDNYYKRIEPADAFVLQKDLREMPKE IKEIKDFLLTARR----------------------------------------------- ------------------------------------------------------------ -------------------------------------------------ASDSLIKQIPR ILGPGLNKAGKFPTMLTHSEAMNVKVDDVKATIKFQMKKVLCLAVCIGHVNMTQDELVSN IVLAVNFLASLLKKNWQNIRSLYIKSTMGKSQRIYMADTDKLNIDSIIARLLEVRGSRPG KNVQLTENEIRSLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLNAGRPVTPPRGAAKNK GKMMFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEIVGTNVSTT YITCPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPF ICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDEL PAEFKLYLPVQNKMEEQNIQNLEDPFTTDSEIHIRIQQRNGRKTLTTVQGIGADYDLKKI VRTLKKQFACNGTVVEHGEYGEVVQLQGDQRNKVSKFLQEVGLAEQLKVHGF---YSFDG LLVFGLLFICTCAYMRKV-PKLLFAEKKGFMGVFYKGAVVGARLHVPVAALCVLMALYVL LI---------------------------------------------------------- ------------------------------------------------------------ -----------------------GNAIDGKGPLNSKTRSRVGVKAPGIIPRISVKEPMQT GIKAVDSLVPIDR-QRELIIGDRQTGKTAVAIDTIINQKRFNEGADEKAKLYCIYVAIGQ KRSTVAQIVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCAMGEHFRDNGKHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDNFGGGSLTALPIIE TQAGDVSAYIPTNVISITDGQIFLETELFFKGIRPAINVGLSVSRVGSAAQIKAMKQVAG SMKLELAQYREVAAFAQFGSDLDAATQQLLSRGVRLTELLKQGQYVPMAVEEQVAVIFAG VRGHLDKVDPSKITSFEREFLQHIRSSQQDTLKSIREKGMIDDATEIKLKDIVTTFLAGF MESLYSIPYTVLECPNLKIKKPSWVKAPSAMFMFSLVLFSYFLVTGGIIYDVIVEPPSIG STTDERGNSKPVAFMPYRVNGQYIMEGLASSFLFTIGGLGFVMLDQVNSPTTPKLNRILL LCVSFACVLISFFMCRVFMRMKLPMPKVRRSKKPPPEGWELIEPTLDELDQKMREAETEP HEGKRRVEALWPIFRIHHQRARYIYDLFYRRKAISRELYEYCLRENIADKNLIAKWKKQG YENLCCLRCIQTRDTNFGANCICRVPKSKLEEGKVVECVHCGCRGCSGEYAQVTKMLGNG RLEAMCFDGVKRLCHIRGKLRKKVWINQSDIILVGLRDYQDEKADVILKYSADEARSLKS YGELPENAKIDDD-EDNIMFGEFDDVLVRFLMKLSHETVTIELKNGTQVHGTITGVDVSM NTHLKSVKMTLKNRDPVPLDTLSIRGNNIRYFILPDSLPLDTLLIDDAPKSRRRG--MNK PRSEMSQEELTAQEQEEFNTGPLSVLTQSVKNNTQVLINCRNNKKLLGRVKAFDRHCNMV LENVKEMWTEVP-------------KDRYISKMFLRGDSVILVLRNPLPVIIDARGHLLG RLASIVSKTILQGQRVVVVRCEEINI---------------------------------- ------------------------------------------------------------ -----------------------------------------------------------E GNVDKGKKIFVQRCAQCHTTEKGGKHKTGPNLNGLIGRQTGQAAGFAYTAANKSKGITWG KDTLWIYLENPKKYIPGTKMVFAGLKKKQDRADLIAHLQEATKIFVERTLAVIKPDAVCE EIEDIILRSGFTILQKRRVHLTPEQASDFYAEHYGKLFFPSLVAYMSSGPIICMILAKEK GISYWRELVGPTNTMKARQTHPDCLRAIYGTDDQRNGLHGSDSYSSAEREIRFFFPDSVV EPVPVGQVAKDYLSKAVNPTLLKGLTELCKQKPKDPVIWLADWLLENNPNKPKVRMFEAR LVQGNLLKKVLEAVKDLLNEATWDCNSSGMSLQAMDSSHVSLVALMLRSDGFDTYRCDRN LCMGINLGSMSKILKCAANDDAITIKAGDSADNVTFMFESPNGEKVSDYEMKLMDLDSEH LGIPETDYGCVIKLPAGEFQRICRDLSQIGESVVICCTKEGVKFSASGDLGTGNIKLAQT ANVDKEEEAVIIEMQEPVTLTFALRYLNFFTKATPLSAQVSLSMSPDVPLVVEYKIGDMG YVRYYLAPKIEDGDEQKALSAYHTSKSMHKGQIVAVIGAVVDVQFEEGLPPMLNALEVAG RSPRLILEVAQHLGENTVRTIAMDGTEGLVRGQKCTDTGYPIRIPVGPETLGRIMNVIGE PIDERGPIPAKHFASIHAEAPEFIEMSVEQEILETGIKVVDLLAPYAKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIEGGVISLKDDTSKVSLVYG QMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTNKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIS ELGIYPAVDPLDSNSRILDANIVGMEHYTVARGVQKILQDYKSLQDIIAILGMDELSEDD KLTVSRARKIQKFLSQPFQVAEVFT----------------------------------- -----------------------------------------------KHPELEVPNLQVI KALQSLKSRGL------------------------------------------------- ------------------------------------------------------------ ------EMYKDLFPNGDAATFAQHVFDAYDIDSNGYIDFREFLCTISVASRGTIDEKLKW AFNMYDLDGNGYVTKNEVMEILKAIYKMKGNSGKESAARGQREETVDKLFAVLDKNRDDK ISDLEFIIGAKSAPEVLGILQ---MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNL TGLNEQVPHYRQALDMILDLEPDDELEDNPNQSDLIEQAAEMLYGLIHARYVMTNRGIAQ MIEKWQQGDFGYCPRVYCENQPLLPIGLSDIPGESMVKLYCPKCQDVYNPKSSRHHHTDG AYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPLAYELQCQAAANFKSGYSGSKR MTNTKGYRRGTRYMFSRAFKTNGVIPLSTYMKCYKRGDIVDIKGNGAVQKGMPYKAYHGR TGRVFNVTQHAVGVVVNKRVKGKILAKRINLRIEHVKHSNCRLDFLKRVEENNKKKIEAR EKIPLKRQPVQPRTAHFVSTKFNKPEIVEPIKYEFIS-------QVNPGDPSEKWSKITD RSADTLFAREIFTGLNIIISMILKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAICPAQAITIEAETRSDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEY STETHEELLYNKEKLLENGDKWEPEIAANLQADYLYR-----KVVKNDENSHEGGDKEQQ EAIEQIDEVQNEIDRLNEQASEEILKVEQKYNKLRQPYFTKRSDLISKIPNFWVTAFVNH PQVSALLSEEDEEALQFLSKVEVQEFEDIKSGYKINFHFEENPYFENKCISKEFHLNSSK STTIEWKPGKDLTGKSKKRSHEEGDSFFSWFLDHGDAGADELGEVIKDDIWPNPLQYYLA SEIDEEPAEVEGEEDEEKKLTKEEELLLQDFSRNVSTKSSALFYGNSLIVSAIPIWLFWR IHQMDPYVWFGVMTLVATYLVAFAYKNTKFVLKHKIAQKRGEAVSREIMKKVADDKRMTK QEKDERILWKKNEVADYEATTFSIFYNNALFLLLVIVLSFYVLRNFSPALNYVLSIGCAG GLLALFSTSTK--QGKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQT VCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFSRAKSWVKELQRQ ASPNIVIALAGNKADLRNVEYEEAQAYAEENSLLFMETSAKTAMNVNDIFLAIAKKLPTN DQSVNLNADNMAEYLASIFGTEKDKVNCSFYFKIGACRHGERCSRLHNKPTFSQTMVMTN LYINPQNSAQFTMDDVSAQKHYDDFFEEIFVELDEKYGEIEEMNVCDNLGDHLVGNVYVK FRYEEDAEKCVNDTNNRWFNGRPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLRP ISRELRRELYSRRRRSRSRSPPTRRSRSRER-RRRSRERSRERSGMFLTRSEYDRGVNTF SPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVVLAVEKRVTSPLIEPSSIEKIMEVDSHIG CAMSGLIADSRTMIDRARVEAQNHWFTYNEKMSVESVTQAVSNLALAFGDDDADPGAMSR PFGVALLFAGIDENGPQLFHMDPSGTFLQYDAKAIGSASEGAQQALQEIFHKSMTLKEAC KEALKILKQVMEEKLNSTNVEMATVTPGKYFRMFTKEELEDVIKQIAQKTWEMSNNVETI SSVDEIYKYDKKQQQDILTAKPWEKDPHYFKHIKISALALLKMVMHARSGGNLEVMGLLL GKVDGNIMIVMDCFALPVEGTETRVNAQAQAYEYMAAYTESAKAVKRLENAIGWYHSHPG YGCWLSGTDVSTEMLNQQFQEPFVAIVIDPVRTISAGKVNIGAFRTYPKGYKPPDEGPSE YQTIPLNKIEDFGVHCKQYYSLDISYFKSALDRKLLDSLWNKYWVNTLSSSSLLTNADYM TAQVFDLADKLEQSEAQLNRGGFMEKKSEDKLAKATKDGCKNTIESIHGLMSQIIKDKLF NQVGGLPRRIIKETQRLIAEPVAGIKALPDEMNARYFHIEVAGPDDSPYEGGTFKLELFL PEEYPMSAPKVRFMTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPD DPLANDVAEMWKTNETQAIITAKQWTKEYA-ENEELLDYEEEETEETKDVKGTYVSIHSS GFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVICQAKSGMGKTAVFVLATLQ QLEPVDGQVSVIILCHTRELAFQISKEYERFSKYMNNVKNAVFFGGMPIKNDEKVLKMNC PHIVVGTPGRILALAKMLNLKNIKHFVLDECDKMLEALDMRRDVQEIFRMTPHEKQVMMF SATLSKDIRP-------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------ITVEDQLAKGLKLAFDTQFAPQTGKKSGKVKTSYKQDHINVSCDGDF DFAGITIHGTAVAGYNGWLAGYQMSFDKSKLLRNNFAVGYQQDDFTLHTAVNDGTEFSGS VYQKVNRKLDMGVQLQWTAGSNATRFGIAAKYCQDRNTTYRAKVNNASQIGLSVQHKLQD GITFTASSLLEGKNFNAGGHKVGFGLDFEADSVREKALQDYRKKLLEHKELESRLKEMRE QLKELTQKFDKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQIDKSK LKAGTRVALDMTTLTIMRYLPREVDPLVYNMSIEDPGDINYSGIGGLSEQIRELREVIEL PLLNPELFQRVGITPPTGCLLYGPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIGES ARLIREMFGYARDHEPCIIFMDEIDAIRRFSEGTSADREIQRTLMELLNQMDGFDALGQV KIIMATNRPDTLDPALLRPGRLDRKIEIPLPNEQARLEILKIHAGPIAKHGEIDWEAVVK LSDDFNGADLRNVCTEAGMFAIRAERDYVIEEDFMKAVRKVGENKKLETKLDYKPIMGEN IKTVVAKFYNEYMSSTSKKVKLIDAYLFYIMMTGVVQFLYCCLVGTFPFNSFLSGFISCV GSFVLGVCLRVQINPQNKSEFLGISPERAFGDFIFAHVILHLVIMNFIGSLASPSQLLPL ELVDKCIGSKIHIIMKNDKEIVGTLLGFDDFVNMVLEDVIEYESTPEGRRITRLDQILLN GNNITMLVPGGEGPEVIDHYEKPRNVGSLDKTNKRVGTGLVGAPACGDVMKLQIEVDDNG KIVDAKFKTFGCGSAIASSSLATEWIKGKNFDEAANIKNTDIAKELSLPPVKLHCSMLAE DAIKAALHDWKIKNQMLVLVLGDLHVPHRCSNVPAKFKKLLVPGKIQHILCTGNLCTKES FDYLKTLAADVHVVRGDFDENLNYPEQKVVTVGQFRIGLCHGHQVVPWGDIDSLSMVQRQ LDVDILITGHTHRFEAFEHENKFYINPGSATGAYNPLDNEIIPSFVLLDIQQSTVVAYVY QLVGEEVKVERIEYKK----QKAGKVVLVLGGRYAGRKAVIIKNYDDGTSEKSY------ ------------------------------------------------------------ -------------------------------ERTFIMVKPDGVQRGLVGEIIKRFENRGY KLVAMKFMQASEEHLKKHYEDLSGKPFFNGLVKYMSSGPVVPMVWEGQVVAQGRVMLGET NPKDSKPGTIRGDFCINIGRNICHGSDAVESAKKEINLWFKPEELAEWGAHSREWIYE-- ------------------------------------------------------------ ---------------------------------------------------------INT LIRPDGEKKAYVRLAPDYDALDVANK-------------------KNVTSRGSVPKSLKP AEEKYPVGPWLLGLFIFVVCGSAIFEIIQSIRMVKIKGWTAVATWRWVANDDNCGICRMP FDGCCPDCKLPGDDCPLVWGECSHCFHIHCIVKWLNSQQVNQLC-----------MIRFI LIQNRAGKTRLAKWYMHFDDEEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIVYRRYAGL YFCICVDVQDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYSVVDEMFLAGEIRE TSQTKVLKQLMTLSSLE--TIFGKIIRGEIPTTFIYEDDKCVAFDDINPQAPVHFLVIPR KAIRQLSEDQQLLGHLMLVANKVAEQDDGFRVIINDGVNGAQSVFHLHLHIMGGRQMEWP PMGGLISYFSGLFGTKERRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVQYKN LKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSMDRDRIGISKQELVSMLEEEELKKSV LCVYANKQDIEGAMSVTEVANALGLSSIKNRKYQIFKTSAIK------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------RYREERFRQTSESTNQRVLWWSIAQTLILLIT GFWQMRHLKSFFEAKKLVMFYHVSLEHEILLHPRYFGPNLLNVVKQKLFTEVEGTCTGKY GFVIAVTTIDNIGAGVIQPSRGFVEYPVKYKAIVFRPFKGEVLDAVV------------- ------------------------------------------------------------ ----------------------------------------------------------KC KRKTACPGHDKASRIRVIWGKVTRPHG---------------------------MAKKTY DLLFKLLLIGDSGVGKTCLLFRFSDDAFNTTFISTIGIDFKIKTVELGGKKIKLQIWDTA GQERFHTITTSYYRGAMGIMLVYDITNKKTFDNISKWLRNIDEHANEDVEKMILGNKCDM DDKRQVQRETGETIAREHGVPFLETSAKTNVNVEKAFTDLAQAILNKMPQNEHIELHRKR HGYRLDHHEKKRKKEGRKPHEMAQKAKKLRGLKAKLYNKKRHSEKVQMKKTIKMHEERKT KQKTDDNVPEGAVPAYLLDREGQSRAKVLSNMIKQKRKEKAGKWEVPLPKVKAQSQADVF KVVKSGKTKRKAWKRMVTKACYVGEGFTRKPPKFERFIRPMALRFKKAHVTHPELKATFC LPIIGVKKNPNSPLYTTLGVITKGTVIEVNISELGLVTQTGKVIWGKYAQVTNNPENDGC INAVLLVMAARPLITVYSEKGDVSPSNVTLPAVFKAPIRPDIVSFVHSEMKKNSRQPYAV SVKAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRR INVNQKRYALCSAIAASGIPSLVMSKGHRIEEIPEVPLVLSDKVEEIKKTKEAVGVLRKV KAWADIEKVKNSRRFRAGKGKMRNRRRIQRRGPLIIYNQDNGICRAFRNIPGITLLNVSR LNLLKMAPGGHVGRFCVWTESAFKKLDGIYGTWKKAAAEKSNYNLPMPKMTNTDLSRLLK SEEIQKVVRPPQKIRKVAQLKKNPLKNYRVMARLNPYAKVQKKAAKRRAERQAKFDARRG VATITEGGKSRPRKTIASGDEQELATKTLQIQSKRFYLDVKQNRRGRFIKIAEVGAGGKK SRLLLAMSTAAEFRDHLTDFSEHYASLGPPNPDNVPEDGKLKSEVMVKDNRRYYLDLKEN QRGRFLR-------------------------------------EEQSELPEARSMRVEN KMFYFDVGQNRRGVFMRISETNFRTAVTIPERSWVRFRDILSDFVDKAERKLRDAQMRAT INQKLVETGERERLKELLRTRLVECGWRDQLKAYCKEIVRQKGLEHVTVDDLVAEITPKG RALVPDQVKKELLQRIRTFLAQQSNMNIRNAKPEDLMNMQHCNLLNLPENYQMKYYFYHG LSWPQLSYVAEDERGEVVGYVLAKMEEDPEDSVPHGHITSLAVRRTHRRLGLARKLMDQA SRAMVESFNAKYVSLHVRVSNRAALHLYRETLGFQINETEPKYYADGEDAFAMKRDLTEF IEKFMSHTILLVQPSTKPEGRTYSDYETVNEMLEGVCKIYEEYLKRMNPSSPSITYDISQ LFDFVDQLADLSCLVFEKTAGTYKPHNKAWIKEKIYILLRKQAGKMAEEGGEKKQEETKR VVHTYPLIRHSDMNEEMRTEAMELCVTACEKFSTNNETAAKMIKETMDKKFGASWHVVVG EGYGFEITHEVKNLLYMFFGGNVGICVWKCS----------------------------- ----------------------------------GSKVNKKEVVEPVTIIESPPMMIVGL VGYIETPRGLRTFKTLFAEHLSEECRRRFYKNWYRSKKKAFTKASKKWQDESGKKEIAND LERIKKYCKVVRVLAHTQMKVLKKRQKKAHIMEIQINGGTIADKVDWARDHLEKSVPVKQ VFDRDEMIDIIGVTKGKGVKGVTSRWHCKKLPRKTHKGLRKVACIGAWHPARVGFSVARA GQKGYHHRTEINKKVYRIAEGVHAEGGKVIRNNGSTSYDVTEKTINPMGGFPHYGIVNSD FIMIKGCCVGPKKRVITL--------------------------YGHGRFQTPDEKFNFM GPLKKDMQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLG LWDTAGQEDYDRLRPLSYPQTDVFLICFALISPASFENVRAKWYPEVSHHCPNTPIILVG TKLDMREDKEMIEKLREKKLSPITYPQGLAMAKEIGAVKYLECSALTQKGLKTVFDEAIR AVLCPKPRPKKKKGCVLL------------------------------------------ ------------------------SDRDYTYDELLKRVFDIMREKNPDMIAGDKKRFVMK PPQVMKAGTKKTAFSNFSEICKMLHRQPKHLLAFLLAELGTSGSLDSSNQLIIKGRFQQK QIENVLRRYIKEYVTCHTCRSPDTILQRDTRLYFLQCETCGSRCSVSSIKSGFQAVTGRR AALRARTTFDDAVEERVVNEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGK DYSLHRLILGTHTSDEQNHLLIASVQLPNDNAQFDASHYDSEKGEFGGFGSVSGKIEIEI KINHEGEVNRARYMPQNPCVIATKTPSSDVLVFDYTKHPSKPDPNGECHPELRLKGHQKE GYGLSWNPNLNGHLLSASDDHTICLWDINHAPRDGKVIDAMNVFTGHTSVVEDVSWHLLH ESLFGSVADDQKLMIWDTRANASNKPSHIVDAHTAEVNCLSFNPYSEFILATGSADKTVA LWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQSAEDA EDGPPELLFIHGGHTAKISDFTWNPNEPWVVCSVSEDNIMQVWQMAENIYNDEEPDTPAS ELEMETPSRARVYADVNTHRPREYWDYETHVVEWGQQEDYEVVRKLGRGKYSEVFEGYNV TTNEKVVIKVLKPVKKKKIRREIKILENLRGGTNIISLLSIVKDPVSRTPALIFEHVNNT DFKQLYQTFVDYDIRFYTYEVLKALDYCHSMGVMHRDVKPHNVMIDHENRKLRLIDWGLA EFYHPGQEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPFFHGHDNY DQLVRIAKVLGTEDLFVYIDTYQMDLDPRFHDILSRHSRKRWERFVHSENQHLVSGEALD FLDKLLRYDHHDRLTAREAMDHAYF---------------------KQKEKRKLIFKRAE KYVKEYRVKERDEIRLHRQARKSGNFYVPDEPKLAFVIRTRGINGVHPKPRKVMQLFRLR QINNGVFVKLNKATVNMLRIAEPFITWGYPNLKSVRELMYKRGYGKVDGKRLALSDNALI ESKLGHLGIICMEDLIHEIFTVGPNFKLANNFLWHFKLN--------------------- ------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSKAHPPELKKYM DKRLSLKLNGGRNVVGVLRGFDPFMNLVIDEAIEQCKTGEQNAIGMVVIRGNSVVLLEAL DRIEFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTI RLQLWDTAGQERFRSLIPSYIRDSSAAIVVYDITNANSFQQTSKWIDDVRTERGTDVIIM LVGNKTDLSDKRQVSTEEGERKAKELSVMFIETSAKAGYNVKQLFRRVAAALPGMEQPEQ KKMIEVKLKDTPTEPER------------------------------------------R EVTGFAPYERRIMELLRISKDKRALKF---QLGSHIRAKRKREEIQNAIQQMRKAMVDEG TKKTLAQIPLLKTKAGPRDGELWVLRLKEEYQSLIQYVQKNKDDDNDWFRLESNKEGTRW FGKCWYIHELLKYEFDIEFDIPVTFPTTAPEIAIPELDGKTAKMYRGGKICLTDHFKPLW ARNVPKFGIAHAMALGLGPWLAVEIPDLIGKGVVKHKD---------------------- -LNFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNHDEEPIRVGD IVVFKIEGREIPIVHRVLKVHEKEDGAVKFLTKGDNNSVDDRGLYAPGQLWLQKKDVVGR ARGFVPYVGIVTILMNDYPKFKYAVLALLGIFVLIHRE---MNPEYDYLFKLLLIGDSGV GKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYR GAHGIIVVYDVTDQESFSNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEY ADQLGVPFLETSAKNATNVEQAFMTMAAEIKNRMGPQSAPQNVKINASTPVKQSGGGCCE ESLGEEVLRMSTDEIVSRTRLLDNEIKIMKSEVMRIGHELTAQKEKIKENTEKIKVNKTL PYLVSNVIELLDIDPQDAAEEEGANVDLDSQRKGKCAVIKTSTRQTYFLPVIGLVEPEEM KPGDLVGVNKDSYLILEKLPAEFDSRVKAMEVDERPTEQYSDVGGLDKQIQELIEAVVLP MTHKERFEALGIQPPKGVLLYGPPGTGKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGA KLVRDAFALAKEKAPAIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFSSTTD IKVVAATNRVDILDPALLRSGRLDRKIEFPAPNEDARARIMQIHSRKMNVNPDVNFEELA RCTDDFNGAMCKAVCVEAGMIALRRGGTELNHEDYMDAILEVQSKKKANLNYYAKDAADQ NFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRQDKRVKLQIWD TAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDNAQVVLVGNKC DLEDERVVSTERGKQLADQLGLEFFETSAKENINVKAVFERLVDIICDKMSESLDSDPTQ TKRLTENPNPQNSGCQC-----------YISQPRITYKTVSGVNGPLVILDAVKFPKFAE IVNLTLADGSQRSGQVLEVSGSKAVVQVFEGTSGIDAKHTKCEFTGDIMRIPVSEDMLGR VFNGSGKPVDKGPPVLAEDYLDIQGQPINPWSRIYPEEMIQTGISAIDGMNSIARGQKIP IFSANGLPHNEIAAQICRQGGLVKLPDKGVMDSHEDNFAIVFAAMGVNMEIARFFKQDFE ENGSMENVCLFLNLANDPTIERIITPRIALTTAEFLAYQCEKHVLVILTDMSSYAEALRE VSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLT GYITEGQIYVERQLHNRQIYPPINVLPSLSRLMKSAIGQGMTRDDHADVSNQLYACYAIG KDVQAMKAVVGEEALTSDDLLYLEFLSKFEKNFISQGNYENRSIFETLDIGWQLLRIFPK EMLKRIPEKTLNKYYPRDGEGPGFVGIKFCQECNNMLYPKEDKENKILLYACRNCDYQQE AENPCIYVNKIQHEVDEM------------------------------------------ ------------------KPPYKVADISLAEWGRKAIDIAENEMPGLMMMRRVYGGDKPL KGAKIAGCLHMTVQTAVLIETLIELGADVQWSSCNIFSTQDHAAAAMAKRGVPVYAWKGE TDEEYIWCIDQTLIFADGKPLNMILDDGGDLTNLVHEKHPEMLDGIFGLSEETTTGVHNL YKMMQKGTLKCPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGKVAVVAGYGDV GKGCAQALRAFGARVLVAEIDPINALQAAMEGYEVTTVEDGLTRARLFVTATGCKDIITG ENFSNMLEDTIVCNIGHFDTEIAVKWLNENCVSKDTIKPQVDRYTLKNGRHLILLAEGRL VNLGCAMGHPSFVMSNSFTNQVLAQIELWTKKGQLKVGVSFLPKKLDEEVAAAHLEHLGV KMTKLTEDQASYLGIPKEGPFKPEHYRYA-EEEQTPTNAVEEPLDLIRLSLDERIYVKMR NDRELRGRLNAYDQHLNMILGDVEETVTTLEIDEETYEEIYKQTKRNIPMLFVRGDGVIL VSPPMRT-----------------------------------------------LEGPAG TPYAGGIFKVKLVLSKNFPADPPKGFFLTKIFHPNVASNGEICVNTLKKDWKSDYGIKHI LLTIKCLLIVPNAESALNEEAGKLLLEQYDDYSMRAKLYTEIHAKP-------------- ------------------------------------------------------------ ----------------------------------------------YELFKIMYTNMLSE ENAYLWRTSVYLAASASAEFFADIALCPFEAAKVRIQTMPGFARTLREAAPKIYNDEGIR GFYKGIIPLWSRQIPYTMMKFACFERTVEALYKNVVPKPRSECSKAEQLVVTFFAGYIAG VFCAIVSHPADTIVSKLNQDKGSNFIDVGKQLGFIGMWKGLFPRIIMIGTLTALQWFIYD SVKVYFKLPRPPPPEMPESLKRKVQHWMNERYVAVSLLPIIPAALAFWTDNLVSAMVLHT YWRLSGVAEDYIHFTIIALGGLFYFNYNDIGFCEAVRQLYTQL----------------- -----------------------------------------------------------K LHKFELAALANLCPESADEAKALVPSLEGRFEEEELQQILEDIQTKRSFQY--------- --------------------------GTIGHVAHGKSTLVKAISGVQTVRFKNELERNIT IKLGYANAKIYKCDDPEMGRPECYTSRGSSHPDEFPCD--GFGKYKLIRHVSFVDCPGHD ILMATMLNGAAVMDAAFLLVAGNESCPQPQTSEHLAAIEIMKLKHMLILQNKIDLVKETQ AKEQHEQILKFVQGTIAEGAPVIPISAQLKYNVDAVCEYITKKIPIPVRDFTSEPRLIVI RSFDVNKPGCEVEDLKGGVAGGSILRGVLKVGMEIEVRPGIVSKDSEGKLTCNPIFSRIV SLFAETNDLQYAVPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPDIYIELEISYFLLR RLLGVRTEGDKKGAKVQKLSKNEILMVNIGSLSSGGRVSAVKADLAKIVLTNPVCTEIGE KIALSRRVEKHWRLIGWGQIRRGVTVKP------------WVFLPIVVITFLVGIIRHYV TILLSSDKKVDLQQIKDSQALFRSRVLRENGRFIPEHAFRMRKGFFNNDDSGFFMKNPMT DPSMMTDMMKGNLTNVLPMIVIGGWINWAFSGFLTTKVPFPLTLRFKPMLQRGIELVSLD ASWVSSVSWYFLNVFGLRSMYTLILGQDNAADQTRMMQDQMSGGAMGMPQDTSKAFKAES ESLQISEHNWALENVEEELMMFLWDWFTGVLNFLGLYKKSGKLVFLGLDNAGKTTLLSML KDDRMAQPVPTLHPTSEELTMGGMRFTTFDLGGHSQARRVWKDYFPAVDGVVFLIDAFDR SRFVEAKAELHSLLSDEQIATAPVLLLGNKIDIPGAASEEEIRHMFDLHAKTTGKGQIAR SELRPMELFMCSVLKRQGYGEGFRWLAQYI------------------------------ --------------------------------------QFCMELNGLAVKLQNECNPQTC TQMTATEQWIFLCAAHKTPKECPAIDYTRHTLDGAACLLNSNKYFPSRVSIKESSVNKLG SVCRRVYRIFSHAYFHHRALFDEYENETSLCKRFTTYVTKYNLMSRDNLIVPILEDQMPN IKLQSSDGEIFEVDIEIAKQSVIIKTMLEDDDEEEEAVPLPNVNSAILKKVIQWCTYHKD DPPPPEDDENKEKRTDDISSWDAEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMI KGKTPEEIRKTFNIKNDFTPAEEEQVRKENEWCEEKXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------- ------------------------------------------------------------ --------------------------FKELEEESIRDNFVIVYELLDELMDFGYPQTTDS QILQLYITQESNKMEVAPRPPMEVTNAVSWRSGNHKYRKNEVFLDVIESVNILVNATGSV MRSEIVGSIQMRVYLTGMPELRLGLNDKVLFESTGRGKSKSVELEDVKFHQCVRLSRFDN DRTISFIPPDGEFELMSYRLHTHVKPLIWVESIIERHAHSRVEYLIKAKSQFKRRSTANN VEIIVPVPSDADSPKFKTTTGSCKYVAAGNIMKWSIKSFPGGKELLMRAHFKLPSVIKED AEAKPPIHVKFEIPYFTVSGLNVRYLKIIEKSGYQALPWVRYITQNGDYEIRTQMGVLER ISEIEAEMARTQRNKATMGHLGLLKARLAKLRRELIDPKGGGGGGGEGFDVAKTGDARIG FVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDG KGRGKQVITVARTCNIIFMVLDVLKPLGHKKLLEYELEGFGIRLNKTPPNIYYRKKDKGG INLTSTVAQTELDLDTVKSILGEYRIHNADITLKYDATSEDLIDVIEGNRVYIPCIYVLN KIDQISIEELDIIYKIPHCVPISAHHKWNFDDLLEKMWDYLSLCRIYTKPKGQLPDYNSP IVLKNDYTSLEDFCNKIHKSILKEFKHALVW----------------------------- ---------------------------------------------------------VIC GGPGVSDAYYCKECTITEKDRDGCPKIVNLGSAKTDLFYERKKYGFKKRPNLPPISGDKL VGKSEMRKVPVPANRYTPLKENWMKIFTPIVEHLHLQIRFNLKTRNVEIKTCKDTHDIGA LQKAADFVKAFTLGFEVDDALALVRLDDLYLESFEITDVKPLKGDHLARAIGRIAGKGGK TKFTIENVTKTRIILADSKIHLLGSFQNIKIARTAICNLILGSPPSKVYGNMRSVAARSA ERRIKVVNPVAELDGDEMTRIIWANIKEKLIFPYLDLDCKYYDLGLPHRDATDDQVTIDA AEGIKQYKVGIKCATITPDEERVEEFKLKKMWLSPNGTIRNILGGTVFREPIICSTIPRL IPGWTNSIVIGRHAHGDQYKATDFVAPGPGAFEMSFTPAKGGEIVMKCFDFKDGGGVGMG MYNTDESIRGFAHSCFQYALKKKWPLYMSTKNTILKRYDGRFKDIFEEIFQAKYKGDFDK MGIWYEHRLIDDMVAQALKSNGGFVWACKNYDGDVQSDVVAQGYGSLGLMTSVLMCPDGE TIEAEAAHGTVTRHYREHQKGNPTSTNPVASIFAWTRGLEHRALLDNTPELAKWCQTMEK ACVDTIDSGKMTKDLAGCIYGIKNVKPEQYLVTSDFLDAINEEF-XXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFGDLKSDAGQKALNEFLEER SYIEGFQASQADAAVFSSMSGPKAAYPHALRWYNHIKSY--NVSSLPGIKKAVGSYGPAG DKDDDDDDDFDLFGSEAEKLKEERIAMYAAKKSATLIAKSNIILDVKPWDDETDMKELEN CVRSIEMDGLLWGTSKLVEVGYGIKKLQISCVVEDDKVSTDDLEEKIVEFEDFVQSMDIA AFNKIKVQEIREVTRMERIGAHSHIRGLGLDDALEARQVSQGMVGQPASRRAAGVILEMI KDGKIAGRAVLIAGQPGTGKTAIAMGMAQALGTDTPFTAMAGSEIFSLEMSKTEALTQAF RKSIGVRIKEETEIIEGEVVEIQIDRPATGTGAKVGKLTLKTTEMETIYDLGQKMIESLT KEKVQAGDIITIDKATGKITKLGRSFTRARDYDAMGAQTKFVQCPEGELQKRKEVVHTVS LHEIDVINSRTQGFLALFSGDTGEIKPEVREQINAKVAEWREEGKAEIVPGVLFIDEVHM LDIECFSFLNRALESDMSPVLIMATNRGITRIRGTNYQSPHGIPIDLLDRLLIIATSPYE EKEIKQILKIRCEEEDVEISEDALTVLTRIGMETSLRYSIQLITTANLVCRKRKGTEVSV EDIKRVYSLFLDESRSTQFLKEYQQEFMFHEMAEFDLTTRMGQYLDRHLVFPLLEFLSVK EIYDEHEMLKGKLDLLSNTNMVDFAMDVYRTLYPDQEVPTSLKDKRTDVVIELKRLQGAT EPIIKIFENEEVQIQSTRDGRELFTFLKQNFDFQPEMIDTLYKFAKFQYECGNYSGAAEY LYFARVLLPSTDRNYLNALWGKLASEILMQNWDHALDDLNKLREVIDSSLQSLQQRTWLI HWSLFVFFNHPKGRDQIIDMFLYQPQYLNAIQTMCPHILRYLTTAVITNKAVLKDLVKVI QQESYTYRDPITEFLECLYVNFDFDGAQKKLIECETVLTNDFFLVACLEDFIENARLFIF ETFCRIHQCISINMLAEKLNMTPDEAERWIVNLIRNARLDAKIDSKLGHVVMGTQAVSTY QQVIEKTKGLAFRSQMLVMNIEKKLAPKQMGVHMESVHPGDEVNFPKDGQYVCVHYEGKL ENGTTFDSSRERGLPIIFQIGKKQVIKGWDIGIKKMSVGQRAVLTCSPDYAYGKRGYPGV IPSNSTVKIDVELLQIKMPKYFCDYCDTYLTHDSPSVRKTHCNGRKHKENVRDYYQKWLE DQVQKLVDDTTAAFKQGKIQTNPFAGGGAAIPPPANL-KKPPAPGLPPGGAPPAG--PP- -----APGPMPPMPL--EPLSLQRDVQRAIELLDHLQKSGDFQKLAALQKVLQSEFCTAV REVYENVYETVDIAGSPEVRANATAKATVAAFAASEGHAHPRVVELPKTEEGLGFNVMGG KEQNSPIYISRIIPGGVADRHQGLKRGDQLLSVNGVSVEGEPHEKAVDLLKQAQGTVKLV VRYTPKVLEEMEARFDKQRSAARRR---LLGSVICDTTILFKEEFWRERWVDSTHKGAEQ GLFKLSAGKFYGDEEKDKGLQTSQDAHFYGISAKFNQKYDNTGKSFVVQFTVKHEQNIDC GGGYAKLFPSDLAQKDMHGESPYNIMFGPDICGPGTKKVHVIFNYKGKNLLVKKDIRCKD DVFTHLYTLIVRSDNTYEVKIDNKKVESGDLESDWDFLQPKKIKDPEAKKPDDWDDREKI DDADDAKP---------------------------------------------------- ------------------------------------------------------------ --------------------------------------------MDYTLPEPSLYVVKAI LILDNDGNRLISKYYDDTFSTVKEQKNLFSKTHRANAEIIMLEGLTCVYRSNVDLFFYVV GSAMENELILVSVLNCLYDSVSHMLRKNVEKKALLENLDGVFLAIDEICDSGIILESDPM NVVHRVNYRSDDIPLGEQTVAQVIQSAKEQIKWSLLK----------------------- ------------------------------------------------------------ --YDSNHDTFRMEFLIVPVAGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGE AESITSHYLFALGSYRALYILNWIYRYYFEGFFDLIAVVAGCVQTVLYCDFFYLYITKVW KGKKLTLPAMKIEEVKSTTKTQRIATHSHVKGLGLDENGFAIQSAAGLVGQELAREAAGV ISEMIKSKKMAGRAVLLAGPPGTGKTAIALAIAQELGSKVPFCPMVGSEVYSTEIKKTEV LMENFRRAIGLRIKETKEVYEGEVTELTPAETENPMGGYGKTVSHVVIGLKTAKGTKQLK LDPSIYESLQKEKVEVGDVIYIEANSGAVKRQGRSDTYATEYDLEAEEYVPLPKGDVHKK KEIIQDVTLHDLDVANARPQGGQDIMSMMGQLMKPKKTEITDKLRKEINKVVNKYIDQGI AELVPGVLFIDEVHMLDIECFTYLHRALESTIAPIVIFATNRGKCTIRGTEDLTSPHGIP LDLLDRLMIIRTLPYSQEEMAQIIKIRATTEGIPVCDDSLQLLSEIGVKTTLRYAVQLLT PSNIFTKINGKESIGREEIEEINELFFDAKSSAKILAEQEDKFLKDFEVDDEGDQGLQKL KEKVKRRKGRGF-TKTDVNQYEGMDIDGPGPQRSVEGWILFITNVHEEATEDDIIDKFRD YGEIKNLHLNLDRRTGFLKGYTLVEYETFSEAQSAMENLNGTDILGQKINVDWAFVRGP- ---MSYQLYRNTTIGHTLQESLDELIQSGQISPQLALRVLLQFDKAVNNALATRVKNRLH FRGHLNTYRFCDNVWTFVLDDVEFRKVEKVKIVACDGKS--------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------PDSKTQVTCEYKLEKGACIPVRVHTVVISIQHSEEVTLED LRTDLMEKVVKTVIPSKYLDSQTIYHLQPSGRFVIGGPQSDAGLTGRKIIVDTYGGWGAH GGGAFSGKDFSKVDRSAAYAARWVAKSLVKSGLCRRVLVQVSYAIGVAEPLSVFLTTYGT GIKPDAEILAITKKNFDLRPGKIVNDLDLKRPIYQRTATYGHFGRPEFPWEDSKKLVFXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMRLEKCYFCSSTIYPGH GTSFVRNDCKVFRFCRGKCHKAFKKKRNPRKVKWTKAFRKAAGKELTVDPAFEFEKRRHV PVKYERQLWQNTVRAMKRIEEIKIKRQNQYILNRLKKGKELRKAADVNEVKKNIHLIKSP A--MTTYKVVMIRHGESEWNKMNKFCGWFDADLSELGIEEAKSGGKMLKEKGWQFDIAFT SVLKRAIKTLYYVQDEMDLHWIPVQRHWRLNERMYGALQGLNKAETAAKHGEEQVKIWRR SYDTPPPTVEISDERWPGHDPKYQYVDKQLIPRSECLKDTV------------------- -----------------------------NIPTGIPLVYELDGDLKPIKHYYLADEAAVK AAMDKVAAQGKAKMELQDMLYNKSEYIETASGNKVSRQSVLCGSQNIVLNGKTVIMADCI IRGDLANVRIGRHCVISKRTVIRPPFKKFSKGVAFFPLHIGDHVFIDEDTIINAAQIGSY VHIGKNCVIGRRCVLKDCCAIADNTVLPPETVVPPFTLFSGCP----------------- --------QYELMKHAAATLGSGDLRMAVQLPEGEDRYEWIAVNTVDFFNQINMLYGTVT EFCREDTCPIMSAGPKYEYHWAD------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------KAGGEIITFDQLALRSPKGQNTVLLQGPRKSRE-------------- ------------------------------------------------------------ ----------------------------------------------------SRLAAPFI TDGVTIRVVLNLLTERFTVYVTERAGERMCNDLTHLGIPTVMVLDSAVGYIMEKIDMVLV GAEGVVENGGIINKGTNTISVVAKAMNKPVYVLAESFKFTRLYPLN-QDIPNQFKFPSSK EHPMVDYTPPGYISLLFTDLGILTPS---------------------------------- ----EYTEGDALDALGLKRYCCRRMLLAHVDLIEKLLNYAPLD-KSPDPVEGRKHIDVQT ELYLEELSDRVEEADAEAQTDTFLDRPPSPMFVPAKTGKDIATQIHDGDLFDFDIEVKPI LEVLVGKSIEQSLLEVMEEEELSNLRSQQRAFEELRNAELVEQQRLEEQERRHREEKERR MKQQREILRKERETADKIAARAFAQSYLSDLVPSVFGTLSDNGYFYDPVERDVEQGFMPW LMERVEVQLTKSTLGRTMLDSIIREVVQKRSEAFAKMRARGDLKEYKVIGRMLPTPKDRN PQLYQMRIFAPDPPSARSRFWYFAALLKKMKKTLGEILACEQIHEKKPEQIKNYGI---- ------------------------------------------------------------ --NSKIKFPLTHRISKRLHAPRFAVSRPATCFSATEEMKDFWKKNEGRPSSPWTIYHFHM PMATSLTHRITGVVMGVALYGIAIGTLAYPGDFTSLVELIKSLDIPKPVMFTFKTIAAFP LIYHYINGIRHLSWDAGYGFRLSTQYKTGTIIAASAAY--------------------EQ DRLLLASTTLYVGNLSFYTTEEQIHELFSRGGDVKRIIMGLDKFKKTPCGFCFVEYYTRE DSENCMRYINGTRLDDRIVRTDWDAGFKEGRQYGRGKSGGQVRDEYRTDYDTGRGGYGQI TNQKV----------------------------------------------KFEKTISGH KLGISDVAWSTDSRLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVS GSFDESVREGKLKGQIQAHFSLIYDLCWARGDRHILSASADGTARVWDTVNNTAVKTLVD GDDVHISCLRVHPNGRRLLVHCRDNSIKMIDLRVGAVMQRYIGALNFREHIRSTMSPC-G SFVTAGSEDCCAYIWNTETGDQVAMYSGYKSPVCDVDFHTQDNIIAFCSFSENSPVIVYK YD-MHLYKDIFGNDELLADTYPGMILKAKAKSDAAIGGNKSTVLNIVGTTKKDYQTYIKD YMKRLADYQFYQGIVLCKWEDAYFYYFRQGLVEEK-MAVEFAEGVVFAADTRTTTGSYVA NRVTDKLTKVTDQIYCCRSGSAADTQAIADIVNYHLGFHKMQMGEEPLVKTAASVFQDLC YNYRDQLSAGIIVAGWDKRKGGQVYSIPIGGMCVRMPFATGGSGSTYIYGYVDAHYKEGM TKDECIKFCTNAVSLAISRDGSSGGLVRLACITKDGVERKTVMHDDQPKFIAIAIAALLL LLCCCVCICKKCCRKKKKDGGKKGLKGAVDLKSVQLLGNTMKEKVQPDLEELEVNMEDNE DAESNKSEVKLGKLQFSLDYDFQKGELAVGVIQAADLPGMDMSGTSDPYVKVYLLP---- KFETKVHRKTLNPVFNETFTFKVPFAEIGAKTLTFAIYDFDRFSKHDQIGQVKVPLNSVD LGRVVEEWRDLTSPESDSEKENKLGDICFS------------------------------ ---------------------------PYYNESFTFEVSFEQIQKISLIVTVVDYDRIGT SEAIGCVILGANAAGTGLRHWNDMLANPRRPIAQWHTLEEVPEK---------------- ------------------------------------------------------------ ------------------------------FVGLQGSGKTTTCTKLAYHYQRKNWKTCLV CADTFRAGAFDQIKQNATKARIPYYGVDTSGRHKQEDSLFEEMLQVSNASPDNIVYVMDA TIGQACEAQARAFKEKVDVASVIITKLDFHAKGGGALSAVTHSPIIFIGTGEHIDD---- ------------------------------------------------------------ ---------MSILAYNGGAIIAMKGKNCVAIASDKRFGVQGQTLGFDFSKIVEMGPTLYC GLPGLATDTQTVAQRLKFRLNLYELRENRRIKPKTFLSMVSNLLYERRFGPYFIEPVIAG LDPKTGESHISSLDLIGCPMETEDFVVSGTCGDQMAGMCESLWKPDMNPDELFECISQAL LNAVDRDAISGWGAVVHMIEKDKVTTRHLKGRMDMTSKDYYFDSYAHFGIHEEMLKDEVR TITYRNSMYHNKHLFHGKVVLDVGCGTGILCMFAAKAGAAKVIGIECSSIVEHAQKIVKA NGLDHIVTLVKGKVEEVQLPDGIEKVDIIISEWMGYCLFYESMLNTVIFARDKWLAPGGL IFPDRATLYVTAIEDRQYKDDKINWWDNVYGFDMSCIRKVAISEPLVDVVDPKQVVSNSC LIK--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --LGPEKTSFFQALSIPTKIAKGTIEILH---------------------IDQNPALEKL LPHLKGNVGFVFTK-----SDDDLRARFMEGVTNIASISLAIGYP--------------- ------------------------------------------------------------ ---------------------AIILINQNIAEMIRHILDQYVKAIPSVLEIPSKDFPYDA SKDSILRRAKGMFSAEDYRGNESSLPMELCSNFDPEEIKRLGKRFKKLDLDNSGSLSVDE FMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVRGDKESKLRFAFKIYDMD KDGYISNGELFTVLKMMVGNNLKDAQLQQIVDKTIIFADSDGDGKISFEEFCGVVGNLDF YKKMVVEVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXLFEEVKLYKNAREREKYDNLADLYAVINTLQCLEK AYIKDCVTPREYTAECSKLLVQFKVAFKIIQGEEYPTVESFMYKTKLNCPLALERIKEGR PITIKDNKGNISKCIADTVSLFITIMDKLRLEIKAMDEIYPDMKELSETMHRLSILPPDF EGLLKVESWLSTLNEMQASDELSESQVRQLLFDLDSAYNAFNRSLHNMLAAMLKEHQQKQ QLRKEQQEIKKKEASLAAALSHALVDHLNAGVAQAYVNQKKLDTETKILQNNTSHFAKQT VQWLKLIEDFNTSLKEIGDVENWSRSIETDMRTISTALEYAYKXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXLEWLFGKKKTPQEILRQNQRALNKAMRDLDRERQKMEQQEKKVIADIKKMAKQGQMDA VKIMAKDLVRTRRYVKKFIMMRANIQAVSLKIQTLKANDSMAQAMKGVTKAMATMNKQLK LPQIQKIMMEFEKQSEIMDMKEEMMNDAIDDAMGDEDDEEESDAVVNQVLDELGLTMADQ LSDLPTTNQS-NKQPAGVSDADADLEARLENLKRKGKYCDFCLGDAVENKKTGMKEELVS CADCGRSGHPTCLQFTANMIISVKKYPWQCIECKSCGLCGTSENDDQLLFCDDCDRGFHM YCLKPPLSQPPDGNWSCHLCIEEFYG-LDRTIHLYPLTNYTFGTKEALYEKDGSVPARFQ RMRDEFDKLGMRRSVEGVLIVHEHGLPHVLLLQLGTTFFKLPGGELDTGEDQSSGLKRLL TEMLGRSDQAPVDWAVEDTIGNWWRPNFEPPQYPYIPAHITKPKEHKRLFLVQLPDKALF AVPRNYKLVAAPLFELYDNAAGYGPIIASLPQTLSRFNFIYNFTPSGTTPVGSKAMAMAT PTPGHLMPMTPEQMQAWTWQREIDERNRILSDDELDAMLPPGYKTLQPPAGYVPIRTPAR KLIATPTPMAGTPMGFRMQQAVVDLQPKGNLPILKPDDMQYFDRKIMKLLLKIKNGTPPM RKAALRQITDKAREMGAGSLFNQILPLLMSPTLEDQERHLLVKVIDRILYKLDDLVRPYV HKILVVIEPLLIDEDYYARVEGREIISNLAKAAGLATMISTMRPDIDNMDEYVRNTTARA FAVVASALGIPSLLPFLKAVCKSKKSWQARHTGIKIVQQISILMGCAILPHLRNLVEIIE HGLVDEQQKVRTITALALAALAEAATPYGIESFDSVLKPLWKGIRMHRGKGLAAFLKAIG YLIPLMDAEYANYYTREVMLILIREFQSPDEEMKKIVLKVVKQCCATDGVEPQYIKDEIL PPFFKHFWNQRMALERRNYRQLVDTTVEIANKVGASEIITRVVDDLKDENEQYRKMVMET IEKIMANLGAADIDSRLEEQLIDGILYAFQEQTTEDVVMLNGFGTIVNSLGKRVKPYLPQ ICGTILWRLNNKSAKVRQQAADLISRIAVVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLG SILGALKAIVNVIGMTKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGAEFVS AREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVC TTVAIAIVAETCSPFTVLPGLMNEYRVPELNVQNGVLKSLSFMFEYIGEMSKDYIYAVAP LLEDALMDRDLVHRQTAMASIQHLALGVYGFGCEDALTHLLNFVWPNVFETSPHVVQAFM GAIEGMRVGLGAHKILQYTLQGLFHPARKVRDVYWKVYNTVYIGAQDTLVPAYPRITNDD KNSYLRYELDYIL----------------------------------------------- ----------------------------------------------------RNHSEKSI NSILDYISTSKQMELLQNFYETTLEALREAKNDRLWFKTNTKLGKLYFDREEFTRLQKIL KQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTSQKNNKKLKALYEKSLHIKSAIPHPL IMGVIRECGGKMHLREGEYEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGIN PFDSQEAKPYKNDPEILAMTNLVSAYQNNDINEFEKILKTNRRNIMEDPFI--------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------LIYVFDVESRELER DMHYYQSCLEAILQNSPDAKIFCLVHKMDLVQDDQRDKIFVERELDLKRLSKPLATSIWD ETLYKAWSSIVYQLIPNVQQLEVNLAHFAD------ILLFERATFLVISHCQRKEHRDVH RFEKISNIIKQFKLSCSKLAAAFQSMEVRNSNFAAFIDTFTSNTYVMVIMSDPTILSAAT LINIKNARKHFEKLERVES----------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------LAYFYMVSSWGGYVFLINLIPLHVLALMVTGRFSHRIYVAYCTVYCLGT ILSMQISFVGFQPVQSSEHMAALGVFGLCQIHAFVDYVRSKLSKEQFDILFRFMVLVSGS LVATALGKIAPWTGRFYSLLDPSYAKNNIPIIASVSEHQPTTWSSFYFDLQMLVFMFPAG LYFCFKKLTDANIFIIMYGVTSIYFAGVMVRLMLVLAPVMCILAGIAVSSTLSTFMKNLD S-KRSDSNYPVKNEVASGVIFLMTLFLILYTFHCTWVTSEAYSSPSIVLSARGGDGGRII FDDFREAYYWLRHNTPEDAKVMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMSS TEDKAYEIMRELDVNYVLVIFGGLTGYSSDDINKFLWMVRIGGSTDRGAHIKETDYYTPQ GEFRVDKEGSPTLLNCLMYKMCYYRFGSVYTEQGKATGYDRVRNAEIGNKDFELDVLEEA YTTEHWLVRIYKVKDLTNRGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----SGVNKGLLNSLKDSIVQGFQWGTREGPLCDEPIRNCKFKILDAVIAEEPIHRGGGQ VIPTARRVAYSAFLMATPRLMEPYCFVEVQAPADCVSAVYTVLARRRGHVTQDAPIPGSP LYIIKAFIPAIDSFGFETDLRTHTQGQAFCMSVFHHWQIVPGDPLDKSIVIRPLEPQPAT HL-------------------------------------------QETFNLFDNRGDGKI FANQIGDVLRALGQNPTEAEVKKCNDGDYRISFEQFLPIYTTVSKNKDTSSLEDFVEGFR VFDKEQNGTIASAELRHLMTSLGERLTDDECSELFQGYEDTQGNINYEEFIKMVLSGMAE MTFNINNGYLEGLCRGFKGGILKQTDYLNLVQCETLEDLKLHLQSTDYGNFLANEASPLT VSVIDDKLKEKLVVEFQHMRNQALEPLATFMDYITYSYMIDNIVLLITGTLHQRAISELI PKCHPLGSFEQMEAIHIASTPAELYNAVLVDTPLAPYFIDCISEQDLDEMNIEIIRNTLY KAYLEDFYKFCEEQGGPTADVMCEALAFEADRRAFIITINSFGTELTKDDRAKLYPRCGN LYPNGLAALARADDYEQVRAVAEYYMQYKQLFDDSGTNPGDKTLEDKFFEYEVTLMKNSF LQQFNLGVFYSFVKLKEQECRNIIWISECIAQRHRAKIDSYIPIF--------------- -----ELQDDFYLNLVDWSSQNVLSVGLGSCVYLWSACTSQVTRLCDLSVDGDSVTSVSW AERGNQVSVGTHKGYVQVWDVAMNKRVNVLEGHSARVGALAWNGDILSSGSRDRLILQRD IRTPSVMPERRLTGHRQEVCGLKWSPDRQHLASGGNDNKLFVWNTSSCTPVQTYTEHLAA VKAIAWSPHQHGLLASGGGTADRCIRFWNTLTG-PLQCVDTGSQVCNLAWSKHSNEVVST HGYSQNQILVWKYPSLVQIAKLTGHSYRVLYLAMSPDGESIVTGAGDETLRFWNVFSKTR STKESNSVLNMFTRIRFLLFIGLYYMLTGQGWKLDFGWFLMAVSPYLWCNIGVGLAISLS VVGAAWGIYTTGSSILGGGVKAPRIRTKNLVSIIFCEAVAIYGIIMAIVMS---NYLAGY AMLAGGLTVGLSNLFCGVSVGIVGSGAALADAQNPTLFVRILIVEIFASAIGLFGVIVSI LMTTKLHMGNKMAATRRLGKELKDIVDDSNVLLWQGLMVPDNPPYNKGAFRIEINFPAEY PFKPPKVTFKTKIYHPNVDEKGQVCLPIISPENWKPATKADQVIQALLALINDPEPEHPL RAELAEEYTKDKKKFMKNAEEHTKKFAEKRP--GASATYPVQCSSLRKGGYVCIKGKPCK IVDMSTSKTGKHGHAKVHMTALDIFENKKLEENCPSTHNMDVPRVERIEYQIILLDDGFF HLLTDDGEEKNDIKFNACVLRALGEETVKEVK---DTLKKALSVALNCLGHIIIADFELH TVFIFDKQGRLLRKFGEKGPGQFLHPTFVCVGEDDCIIVSDGDNHRIQVFDMGKFLYTFG RKGNGKGEFAMPFGVAADLHGNILVVDGGNKRVQIFKTDGMFVSCIELNAPRGIAVTSDG YVLVADRDNHCIKKYRYLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXX---------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------NFNERADEIRRHWGGGIMGNK SQARVA-------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--ISKIHAR QIFDSRGNPTVEVDLTTDKGLFRAAVPSGASTGIYEALELRDKDPKAYHGKGVSKAVNNV NNIIAPALLLDLTNQAAVDKILLDLDGTENKGKFGANAILGVSLAVCKAGAAQKGVPLYK HLADLAGNPDVILPVPAFNVINGGSHAGNRLAMQEFMILPTGADSFTEAVRMGTEVYHHL KKVIKDKYGQDACNVGDEGGFAPNIQDNNEGLELLMTAIEKAGYTGKIKIGMDVAASEFY KKYDLDFKNPNSDPATYLSSDQLLSLYQDFVKKYPVVSIEDAYDQDDWDAWAKMNGTQLV GDDLLVTNPTRVKDAIEKKACNALLLKVNQIGSVTESIEACKMSQKAGWGVMVSHRSGET EDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELGENAKYAGVNFRNPRAPPA AGAFKERSARPTAFRKFYERGDFPIALEHDTKGNKIAWKVEIEKLDYHHYLPLFFDGLCE TTHPYEFFARQGVHDMLEHGGSKILPVIPQLIIPIKNALNTRNRSVICTTLKILQHLVVS ADIVGEALVPYYRQMLPILNIFKNSNLNSGDGIDYSQQKRENIGDLIQETLEAFERHGGE DAFINIKYMVPTYESCMMNAPPSFASFLLFEGEKKITIEKDTKVPNAAIFTVNKEDHTLG NMLRTQLLKDPQIIFAGYKVPHPLENKIIIRIQTTADYSPQEALTNAITDLISEISLLEE RFKEAIREKQD--EDHRRKWDDDEFERIATERLKEELSKKEKPIRREHLKPREYQVDLDS KLGKSQVITKTTPASQQGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLD QVKKRFEMNKRKREEKKKDYDFEERMRELKEEDEKQKAYRREKQKNRKRKADTSEGNDDM AAVMGFSGFGTTSKMGCTMSAEDRLAMERNRQIEKNLKEDGIQAAKDIKLLLLGAGESGK STIVKQMRIIHEGGFTNEDNKQFKPVVYSNTIQSLVAIIRAMGTLNIAFGDPERESDAKM VLDVIARMEDTEPFSEELLAAMKRLWKDSGVQECFGRSNEYQLNDSAKYFLDDLDRLGQK DYMPTEQDILRTRVKTTGIVEVHFHFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCV AMSEYDQVLHEDETTNRMQESLKLFDSICNNKWFTDTSEEKIKKSPLTICFPEYTGKQTY EEAAAYIQAQFEAKNKSTTKEIYCHQTCATDTNNIQFVFDAVTDVIIANNLRGCGLY--- --------------------------------IHFFKANVFFKNYEIKSEADRTLIYITL YITECLKKLQKCQSKNAGQKEMHTLAISRFGIPGEPDFPLNAMYLKPVNK--EDTMRSYL TQIRQETGLRVCEKVFDPATDKPSKWWMCFVKRKFMDKSLSAPG-AGPYNYSYIFKYIII GDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVAGQKIKLQIWDTAGQERFRAVT RSYYRGAAGALMVYDITRRSTYNHLSSWITDARNLTNPNTVIFLIGNKCDLEAQRDVTYE EAKQFAEENGLMFLECSAKTGENVEEAFLDTARKIYQNIQDGSLDLNAAESGVQHKPSAP RNTLSNDTTQNKEGCACMSVNAVCVLK-ADVQGTVNFTKDG-VKITGEITGLAQGEHGFH IHEFGDNTNGCTSAGPHYNPAGKEHGAPTDEVRHTGDLGNVTADKIDITDKMVSLIGTTS VIGRTVVVHADIDDLGKGGHE---------------------MVNFTVDEIREIMDKKKN IRNMSVIAHVDHGKSTLTDSLVSKAGIIAGAKAGEARFTDTRKDEQERCITIKSTAISLY YTLDEKDLNSAFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQA IAERIKPVVFMNKMDLALLTLQLEKEDLYQKFQRIVESVNVIIGTYAEDDGPMGDITVDP AKGNVGFGSGLHGWAFTLKQFAEMYSSKFKIEVPKLMKRLWGDQFFSYKRGFVQYILDPI YQVFHCSMSKEKTILLLEKLGVKLTSEEKELEQKPLLKTIMRKWLPAGDTLLQMITIHLP SPVTAQKYRMEMLYEGPLDDAAAVAIKSCDPEGPVMMY----------GRFTAFGRVFSG TVATGQKVRIMGPNYQPIKTIPRTLVMMGASVMAVDDVPCGNVCGLVGIDKYLLKTGTIS TYDAAHNLRVLRFSVSPVVRVAVDVKQPAELPKLLEGLKRLAKSDPMVQISVE-NGQNII AGAGELHLEICLNDLENEYASVEIKKSDPVVMYKETIGEPSSKVCLAKSTNKHNRVYMTA SPLQDGLAEEIEEGKIHPSQDVKERARYLADTFDWDAAEGRKIWSFGPEGRGPNILTDVT KGIQNLSDIKDMVVAGFQWATQEGPLCEENMRGVRIHITDAMVHNDPACRKGGQVIPAAR RCVLSSVLTASPRIMEPVYLVDIQCPQSNISTIYSVMNKRRGAIFDEQQILGSPMYNIKA HLPVNESFGFSEELRAQTSGQAFPQCVFDHWQILIVRDIRKRKGMQENVPTVETFLDKLM LPLSLLRTAVNHPMLVELKNGETYNGHLVSCDNWMNINLREVICTSRDGDKFWRMPECYV RGSTIKYLRIPDEVIDMVKEEAIQRSKGRGEGRVRGRGGPGRGAFGARGGR--GGGRGGG RGA--------------------------------------------------------- --------------------------SEQVVGTHSAPIRCVEYCPEVNVVVTGSWDSSVK LWDPRTPCSAGSFSQPERVYTMTVCGDKLIVGTAGRKVLVWDLRNMGYVQQRRESSLKYQ TRCIRAFPNKQGYVLSSIEGRVAVEYLDPSPEVQKKKYAFKCHRIKENGVEQIYPVNAIA FHNQYNTFATGGSDGLVNVWDGFNKKRLCQFHRYPTSIGSLAFSSDGSLLAIASTYMYEQ GKPDDTIFIRKVSDQETKPKMDFQHRAGGKTGVGGVASASESNRDRRERLRQLALETIDI NKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQANLARRAAKEAKEAPAQPAPA KPQVDIKKFVKIGRPGYKVTKQRDPETGQQSLLFQIDYPEIVDIIHPRHRFMSAYEQKVE PPDRKWQYLLFAAEPYETIAFKVPSREVDKDSKKFWTHWNKETKQFFLQFAFKHDPK-AP PPPPSAMPPPPRMDDEQETYRLWRIRKTIMQLCHDRGYLVTQDELDQTSDQFKEQFGDKP SERRPARSDLIVLVAHNDDPTDQMFVFFPDEPKVGIKTIKTYCQRMQEENIHRAIIVVQQ GMTPSAKQSLVDMAPKYNLEQFLEAELLVNITEHQLVPEHVLMTPEEKKELLERYKLKES QLPRIQQGDPVARYFGLKRGQVVKIIRPSETAGRYVSYRLVVDTKDSVGTVIGIDLGTTY SCVGVYKNGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTSNPENTVFDAKRLI GRRWEEPTVQSDVKFFPFSVVNKGGKPHVEILVGADKKVFAAEEISAMVLVKMKETAEAY LGKKIVNAVVTVPAYFNDMQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKKEGEKNI LVFDLGGGTFDVTLLTIDNGVFEVLATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRK SNRSVQKLRREVEKAKRALSSQHQARIEIESFYDGDDFSETLTRAKFEELNMDLFRSTMK PVQKVMEDADLSKNEVDEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEAVAFGAAV QAGVLSGEEDTGDLVLLDVNPLTLGIETVGGVMTKLITRNTVIPTKKAQIFSTAADNQPT VTIQVYEGERPMTKDNHLLGKFDLTGIPPAPRGVPQIEVTFEIDVNGILRVAAEDKGTGN KNDIVIKNDENRLSDEDIERMINDAEKFADDDKKVKERVEARNELESYAYSLKNQVGDKE KLGGKLSDEDKETIEKAINEHIEWLEGHQDAEIEDFQQHKKDLEAIVQPIVSKLYEGPPP ----------ESGVEDPELEAIKARVREMEEEAEKLKEMQSEVEKQMTLEEKADADLRSV YIGNVDYGATAEELEAHFHGCGSINRVTILCDKFTGHPKGFAYVEFADKDSVTTAQALDE SLFRGRQIKVSAKRTNRPGLSTTDRAPRGRGRFSRGAAYYGGYMPRPR--GRYRPRRAMY YSPYVLYGTLLEMSNSGNFQTLIDAVKLEKEKKARLQETILKEEQGRKRMRQLQAQLNDI KKEKEVEIQQRNELIAHYKDQLQEMKAKTNMEGKYIKKCAEVSVSQTQKRCFMSENELRD DIEKLREKIEDETRVNMEIESYLRTHTDRLQKMVEHWMEKYDLDVDAKQKELDILKASKA KDLEKLQELTKTYAEYEQVVVEDRIEKEKARRKAEQEAEELRGAIRLQSWWRGVMVRKGL GPYNKKKKKKPNVGINGFGRIGRLVFRAALNSVPVVAINDPFIDLDYMVYMFKYDSTHGR FKGEVKLVVNGKPVQVFSERDPSNIKWGDAGATYVVESTGVFTTLEKANAHIKGGAKKVV ISAPSADAPMYVMGVNHTSYEPSNNIVSNASCTTNCLAPLAKVINDKFEIIEGLMTTIHA YTATQKTVDGPSAKDWRGGRTAAQNIIPSSTGAAKAVGKVIPELNGKLTGMAFRVPVPDV SVVDLTCRLGKGASYDEIKAAVKGPMKGFLAYTEDMVVSTDFIGDTNSSIFDAKAGISLN NNFVKLVAWYDNEFGYSHRVIDLIKH-----KEDLATAILRTKSKPNRLLVEEAINEDNS VVSLSQAKMDELQLFRGDTVLLKGKRRKETVCIVLSDETISDEKIRINRCVRNNLRVRLG DVVSVQACPDVKYGKRVHVLPIDDTVEGITGNLFEVYLKPYFLEAYRPLHKGDIFLVRGG MRGVEFKVIETDPSPYCIVAPDTVIHCEGEPVKREEEEEALNEVGYDDIGGCRKQLAQIK EMVELPLRHPQLFKAIGVKPPRGIMLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSK LAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQ RSHVIVMAATNRPNSVDGALRRFGRFDREVDIGIPDATGRLEILRIHTKNMKLSDDVDLE QVAAETHGHVGADLAALCSEAALQQIREKMDLIDLEDDQLDAEVLDSLAVTQENFRWALS KSNPSALRETAVEVPTVTWEDVGGLENVKKELQELVQYPVEHPDKFLKFGMTPSKGVLFY GPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFD ELDSIAKARGGNVGDGGGAADRVINQLLTEMDGMSSKKNVFIIGATNRPDIIDPAILRPG RLDQLIYIPLPDDKSRISILKANLRKSPVAKDVDIDFLAKSTQGFSGADLTEICQRACKM AIRESIETEIRRERQRADNPDESDEVPEIRRDHFEEAMKFARRSVTDNDIRKYEMFAQTL QQSRGLGGGQTGTFGSTSVFGSTTNHNPMKDVEVTSPPDDSVSSLEFSPGVLPSTFLVAG SWDNNVRCWEVQQNGQTVPKAQQTHTGPVLDVCWSDDGTKVFTASCDKTAKMWDLNSNQS IQVAQHDAPVKTCHWVKGSNYTCLMTGSWDKTLKFWDTRTPNPMMTINMPERVYCADVKF PMAVVGTAGRRVLIYQLENQPSEYKNIESPLKYQHRCVNIFPDKKTNQPTGFALGSIEGR VATHYVNPTNPKDNFTFKCHRGGYQDIFSVNDIAFHPVHNTLATVGSDGRFSFWDKDART KLKTSEQLDQPISCCAFNAQGQVFAYASSYDWSKGHEGFDPQKMKPHIFLRPCFDELKPS QRKMSSPSPGKRRMDTDVVKLIESHHQVTILGGLNEFIVKFYGPNGTPYEGGVWKVRVDL PEKYPFKSPSIGFMNRIYHPNIDEVSGTVCLDVINQAWTALYDLVNVFESFLPQLLSYPN PIDPLNGEAASLYLHKPEDYKKKVTDYIKKYATEEILREQESSMSSFSEDETQDMEL--- ------------------------------------------------------------ -----ERFRTLTPSYYRGAQGCILVYDVSSKSSFTKLDQWLSELETFATKHDIVKMLVGN KIDKDSREVSREEGLKFARKYHMLFIEASAKTKEGVQCAFEELVEKILQTPGLWETDGLS L--VIWSLINGTFCSFKIRTKTQKFCRNEYNLTGICNRASCPLANSQYATVREEKGVCYL YMKTIERAAFPSRLWEKVKLSRNYEKALKQIDENLLYWPKFLKHKCKQRFTKITQYIIRI RKLTLKRQKKLVPLSRKVERRETRREEKALVAAQLDTAIEKELLDRLKKGTYGDIYNFPQ HAFDKALEAEEVSSEEENEREVEYVAAEDFEESDLSDIE--QVRFKTQPRVKSFKIYRYD PDKPGDKPHMQTYEVDLNRCGPMVLDALIKIKNEIDPTLTFRRSCREGICGSCSMNINGA NTLACLCKIDENTSKTSKIYPLPHMYVVKDLVPDMNNFYAQYKYIEPYLKKKDVKPEDIG KEPYTQSPEDRAKLDGMYECILCACCSTACPSYWWNGDKYLGPAVIMQAYRWVMDSRDEY KQERLDKLKDKWSVYRCHTIMNCTKTCPKGLNPGAAVAELKKILIGQESLGIPRQDIRPN HTIYINNLNEKIKKDELKKSLYAIFSQFGQILDIVAMKNLKMRGQAFVIFKDINSSTNAL RSMQGFPFYDKPMRISYSKRDSDCIAKMKGTFVERPKKKKLPSSKKKRKQQASGVIPEQP PHHILFLTNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFETEAQAGAAKDALQ GFKITPTNAMKISFAKKMDSQGRKVVVCDNGTGFVKCGFAGSNFPSHIFPSLIGRPIIRS SQKVGDIEIKDLMLGDEASQLRSMLEVNYPMENGIVKNWEDMIHLYDYTFGEGKLNINPR DCKLLLTEPPMNPKKNREKMVETMFEHYQFQSLYVAIQAVLTLYAQGLLTGVVVDSGDGV THICPVYEGFALPHLTKRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRLLKEKLCFV GYDIEQEQKLALETTVLVEQYTLPDGRVIRVGGERF------------------------ ------------------------------------------------------------ -------------------------------------------------MSDTAGKPIQC RAAVAWEAKKPLSIENVEVAPPKKGEVRIKITHTGVCHTDAYTLDGFDSEGKFPCILGHE GGGIVESVGEGVTSVKAGDHVIPLYTAQCYDCKFCKNPKTNLCQKVRATQGQGVMPDGSP RFSCKGQPVYHFMGCSTFSEYTVCAEVSVAKVDAGAPLDKVCLLGCGISTGYGAALNTAK VEPESNCAVWGLGAVGLATIMGCQAAGASRIIGVDINPGKFETAKKFGATECVNPKDHDK SIQEVLVQMTDGGLDYTFECVGNVATMRAALESCHKGWGESVIIGVAPAGTEISTRPFQL VTGRVWRGTAFGGWKSRDSVPKLVSDYVAKKLKVDEFISHTMELDKINEAFDLMHKGES- -SYDVIANQPVVIDNGSGVIKAGFAGDQIPKYHFPNYLGRPKHVRVMAGALEGDIFMGPK AEEHRGLLTIKYPMEHGIVTDWNDMERIWSYIYSKDQLQVFSEEHPVLLTEAPL------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------DGTKISKVVVHPLVLLSVVDHFNRMGKVGNMKRVVGVLLGSNRQG VLDISNSFAVPFDEDDKDKTVWFLDHDYLENMYAMFKKVNAREKIVGWYHTGPKLHQNDV AINELVRRYCSNSVLVIIDAKPKDLGLPTEAYIAVEEVHDDGTPTTKTFEHVPSEIGAEE AEEVGVEHLLRDIKDTTVGSLSQRITNQLMGLKGLHSQLKDIHGYLEKVATGKLPINHQI IYQLQDVFNLLPDVNLLNFVKAVYVKTNDQMLVVYLASLIRSIIALHNLINNKVANRDAE RNEGKDSKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXKTIPTRRIVLDHPSQMPSDYSSTPGGTMFSTTPGGTRIIYDRAFLMHCRNSPLA KSPPSNLPKIPGV----------------------------------------------- ----------------------PYPTTKIMWIPDNKGVFPDLLATSGDYLRVWRVTRLEC LLNNNKNSDFCAPLTSFDWNEVDPNLLGTSSIDTTCTIWGLETGQSLG------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------RNFCKSSKVA VLGASGGIGQPMSLLLKINPRITHLSLYDIVHTPGVAADLSHCSTKAQVTGHTGPEEIAA CLKDAEVVVIPAGVPRKPGMTRDDLFNTNASIVANLADAAAKHCPEALICIISNPVNSTV PIASEVFKRRKVYNPDKIFGVTTLDVVRANTFLSQAKGIDVEEITCPVVGGHSGVTIVPL ISQAVPPMSFPTEERQNLTTRIQNAGTEVVEAKAGAGSATLSMAYAGAQFVTSCLKALDG EDDVVECAFVKSDITEVSYFASPVQLGKHGIDRHLGLSKMLDYEVDLLKNAVPELKANIQ KGEEFVAKN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------RRFKKRDCSVFMR RTESGIIDQVMVTINQEGYKFCKIRVRTVKTPQIGDKFASRHGQKGTCGIRYRMEDMPFT CEGMTPDIVINPHAIPSRMTIGHLIECLQGKVSANKGEIGDATPFNDTVNVQKISNLLHE YGYHLRGNEVLFNGHTGRKLNSQVFLGPTYYQRLKHMVDDKIHSRARGPVQILNRQPME- --RDGGLRFGEMERDCQIAHGAAQFLRERLFEVSDPYRVHVCNICGLIAIANLRNNTFEC RGCKNKTHISQIKMPYACKLLFQELMSMSIAPRMMVICVEAPGGFSFDNCNRNAALTKGF KVPKVTKTGTTIVGIVYKDGIVLGADTRATAGPIVADKNCSKIHYIADNIYCCGAGTAAD TEMTTQMISSQIELHKLNTGRTPRVCTANRMLKQMLFRYQGHISAALVLGGVDTTGPHLY CVYPHGSTDSLPYVTMGSGSLAAMAVFEDGYKPNMEVEDAKKLVRDAIAAGIFNDLGSGS NVDVCVITKKVDYIRPYDEANVKGQRQGDYTYKRGTTAVIGESVKKVEVEIVMSKVTFKI TLTSDPKLPYKVLSVPEATPFTAVLKFAAEEFKVPAATSAIITNDGIGINPAQSAGNVFL KHGSELRLIPRDRVGW--FTFAAFCFIVALILSAFLIFFVIYHIIAFDELKTDYKNPIDQ CNSLNPLVLPEYVMHIFYNVLFLFAGCWFTLLLNIPLIAYHVNRYLHRPVMSGMGIYDPT TIMNADELSRAQKEGWIKLAFYLLSFFYYLYSMIYELVSSMGLLTILKKMKQKEKEVRLL MLGLDNAGKTTILKKFNGEDINTISPTLGFNIKTLEHRGFKLNVWDVGGQKSLRSYWRNY FESTDGLIWVVDSADRRRITDCKKELEALLLEERLAGATLLVFANKQDLPGALSSSEIKE ALELDNIKSHHWLIQDCSAVTGENLLNGIDWIIDDIASRIFTLDHSKRKVCYYYDGDIGN YYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATQEEMTKFHSDDYIKFLRSIRP DNMSEYNKQMQRFNVGEDCPVFDGLYEFCQLSTGGSVAGAVKLNKQATDIALNWGGGLHH AKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY GEYFPGTGDLRDIGAGKGKYYAVNFPLRDGIDDESYEHIFQPVMTKVMEMYQPSAIVLQC GADSLSGDRLGCFNLTLKGHGKCVEFMKKYNLPLLMLGGGGYTIRNVARCWTFETSLALG VDIANELPYNDYFEYYGPDFKLHISPSNMANQNTPEYLDKIKTRLFENLRMLPHAPGVQM QDIPEDAVKEEANPDERISIRASDKRIQGDDEYSDSEDEG------------------AS KCSLCLEIRRSSTATPCGHLFCWNCIYEWCQTKPV---CPLCREKFQLSRLI-------- ------------------------------------------------------------ ---------------------------------YALLHKQEQAHDDSIWSCAWGRSDKDG SENIITGSVDDTVKVWKWASLELKYTLEGHQLGVVSVDVNASGSMAASSSLDSSIRIWDI EVGKLRKLIDAGPVDAWTIAFSPDSRLLASGSHTGKINLFGIESGKNETTLDTRGRFTLS IAYSPDGKYIACGAIDGIINIFDMTTGKLLEGHAMPIRGLCFSPDSQLLVTASDDCHMKI YDVKHANLAATLSGHGSWVLNVAFSPDNTHFISCSSDKTVKVW---SRQCVHTFYDHTDQ VWGAKYSGTGMKAVSVSEDRAIHIYDCPVESNEEFDERYVQLLSKEDVDGWEIRKAINDI QGYDLVPEPRIINAALRACRRVNDYALAVRLMEVVKDKCGPKHAVIWPYILQEIQPTLDE LGVLTPEQMGYDKPEFALQE---------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------NYESQTGHCVHMRGLPFAANEQDILDFFKPLNPVNVFIH YQPGRASGESDVDFSTHDEAKEAMSRDRATMQHRYIELFYKDKDKPTQIRFSNITAAKAV ADAIRTSLGPRGMDKMIQEGNGSVTITNDGATILQQMQVLHPAAKMLVELSKAQDVEAGD GTTSVCVIAGSLLDAAQKLLIKGIHPTTISEAFQKASAKSVEILEEMAMPLKLSDRESLL KSATTSLNSKVVSQYSNILSPLCVDAVMKVTDPIKDTNVDLRDIKIIKKLGGTVEDTELI DGLVFSQKTAGYGGPNKVEKAKIGLIQFCISPPKTDMENQVVVSDYTQMDRVLREERQYI LNIVKQIKKAGCNVLLIQKSILRDAVNDLALHFLAKMKIMVVKDIEREDIEFVCKTLGCK PVASLDHFQPDALGTAELVQEEHVGDGKIVKITGIQNAGKTVSVLVRGSNKLVLEEADRS IHDALCVIRCLVKKRAIIAGGGAPEIELSLQLTRYANTLTGMEQYCFREFAQALEIIPFT LAENAGLNPIATVTELRNKHAQGEKTGGINVRKGAITNILEENVVQPLLVSTSAIHLASE TVRSILKIDDIVNCV--------------------------------------------- ------------------------------------------------------------ -------------------------------------------------RVTVIFSTIFK DEDDIVIGKVFMQEFKEGRRNYQQAPQVLFSHKEPPLELQGTDARVGDNICYITFVLFPR HDSRDNTINLIHTLRDYLHYHIKCSKAYIHSRMRAKTSDFLKVLNRARPESKSTEKK--X XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKTKFGDLKDEDRIF TNLYGRHDWRLKGAMKRGDWYKTKEIILKGYEWIQGEVKASGLRGRGGAGFPTGLKWSFM NKPDDGRPKYLVVNADEGEPGTCKDREIMRHDPHKLIEGCLVSGASMGARAAYIYIRGEF YNEASNVQIAIKEAYEAGFLGKDACGSGYDFDVYLHRGAGAYICGEETSLIESLEGKAGK PRLKPPFPADVGVFGCPTTVNNVETVAVAPEICRRGGEWFASFGRPRNTDVLLDFDALVD AQTALGTAALIVMNKQADIVRCIARLMDFYHHESCGQCTPCREGVAWMAKILGRFINGNA KPNEIDMLYEMSKQIEGHTICALGDGAAWPAQGLIRHFRPELEARMASFQEKKFTQEQVD EMNQQLNQTRSQRVRAAMFPETLEEGIQIPSTQIHPDQRTAVQRLSEPSQMLKHAVVNLI NYQDDADLATRAIPELTKLLNDEDQVVVGQACMMVHQLSKKEASRHAIMNSPQMVAALVR AMQNTNDLETQRTCAGTLHNLSHHRQGLLAIFKSGGIPALVKLLSSPVESVLFYAITTLH NLLLHQEGSKMAVRLAGGLQKMVALLQRNNVKFLAITTDCLQILAYGNQESKLIILASGG PESLVRIMRAYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALAMHLTHQSSRLVQN CLWTLRNLSDAATKCDNLEQLLQNLVGLLASNDLNIVTCAAGILSNLTCNNMKNKITVCQ VGGIEAFVRTIMQAGEREDITEPSVCALRHLTSRHPEAEMAQNAVRLHYGLPVLVKLLHP PSRWPLIKAVIGLIRNLALCPANHAPLREHGAIPRIVQLLIRAHQDTQRGRGAYVDGVRM EEIVEGTVGALHILAREAHNRAVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAADKE GAEVIEQEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRGE NMSADLQWLLIRNNSSFLVKRNSFSREANNLKCKNSFRYNGLVHQKTIGIEPASDGKGVV MVTRSNWRRPAKGVSRTEFKKGSRRTLSSIRKVVRNNKYRKDLKMAALRRASAILKSQKP VLVKKSRDEPYYCSQQINIPPELPDILKQFTKSAIRTQPKDVLAWSAAYFRAMANGETPP VKERLEMPVATQKTDTGLTPGLLRVLNKQLGPKKVVPLSLIEEKWKDVALPKEQFDELVR IGNFSGDVEWLKFFALGCSALGENMTDAMKTVCEILTADPEGGPARIPFQLFQDLYKYLA QIDGEISTEHLNQVISHLEYHVLKQDGFVQPRNFLANDCPQLS-------RQTLEENMSK IIQINTAEKLLEKISNNCFKVCVTKPGSSLDNSEQKCLSMCTDRYMECFNLVSKTFVQKL QK-----MNRLFGRSKPKGPAPNLNDCITSIDGRGESIDKKIGRLDQDLAKYRDQMKKMR DGPAKNAVKQKALRVLKQKKMYENQRENLMQQSFNLEQTNYGIQSLKDTKTTVDAMKVGV KQFKKEYKNINXDNIEDLQDELEDLNEQASDIQEVMGRSYGMPDVDEDELEAELDALGDD FALDEDASYLDDAIAAPSAPTGVPGADSVTNKD--------------------------- ------------------------------------------------------------ -KSEEQAKLAARKYARIVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHGQFSSY EPELFPGLIYRMVK---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------QHLITNSFVECN RLLRWCPSPDCGHVIKVQYFEPQPVTCNCNHVFCFACGENWHDPVQCKWLKRWIKKCDDD SETSNWIAANTKECPKCHVTIEKDGGCNHMICQSCKADFCWVCLGPWEPHGSSWYNCNRY ------------------------------------------------------------ ------------------------------------------------------------ --------IKQKVQDKYRYCESRRNVLLDHVHEGYEKETWEYLD---------TSDRTVK SVPFPPSHRLTLSEVFDSKGKPKPDLLKQHFIVEGRLMEDVALRIINDGASLLRQEKTMI DIEAPVTVCGDIH----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------GFSPR GGGRGGFRGGRGGGDRGGRGGGRGGGRGGRGGMRGGRTVVIEPHRHNGVYIARGKEDALV TLNLVPGESVYGEKRMSVEEGKKIEYRAWNPFRSKLAAAILGGIDNIHMKPGSKVLYLGA ASGTTVSHVSDLVGPDGLVYAVEFSHRSGRDLINVAKKRTNIIPIIEDARHPHKYRMLVG MVDCIFADVAQPDQARIVAINAHHFLKNEGHVVISIKANCIDSTAEAEAVFAGEVSKLRG EKIKPKEQITLEPYERDHAVVVGIYRPPAKKMDPNSIKDLGKRMRNAGKGAGIGGGLLAA AGAAMYGLYQSVYTVEGGHRSIIFSRIGGIQPDIYREGLHFRVPWFQYPIIYDIRARPRK ISSPTGSKDLQMVNISLRVLSRPDSTQLPTMYRQLGTDFDERVLPSICNEVLKSVVAKFN ASQLITQRQQVSLLVRKELTERARDFNMILDDVAITELTFGKEYTAAVEAKQIAQQEAQR AQYIVEKAKQERQQKIVNAEGEAKAAKLIGEALTLNPGYLRLKKIRAAQGIARTVASSRN RVYLNAGTLMLNINDESFNSNLE--TGSSSDEDDTNPRDKEQKTSKGLTDFCVKIEHAAF GRREIEIAEQEMPGLMALRKRAQDDKPLAGARVVGCTHITAQTAVLVETLVALGAKVRWA ACNIYSTQNEVASALAESGVPVFAWRGESEEDFWWCIDKCVSTDSWQPNMILDDGGDATH LMLKRYHAMFNTVKGIVEESVTGVHRLYQLSKSGQLTVPAMNVNDSVTKTKFDNLYSCRE SILDALKRTTDVMFGGKQVVVCGYGEVGKGCAQALKGMGAVVMVTEIDPICALQACMDGH KVVKLNEIVRQVDIVITCTGNKNVITREHMDKMKTGCIVCNMGHSNTEIDVNSIRTPDLT WERVRSQVDHIIWQDGKRIILLAEGRLVNLSCSSIPSFVVSVTAATQALALIELYNAPQG RYKRDVYLLPKKMDEYVASLHLPAFD-----------------------------PDPDA IKMFVGQVPRSMDENDLRKMLEEFGPVFQLNVLRDKVTGQSKGCCFITYYTRKAALDAQN ALHNIKTLPGMQHPIQMKPADSEKL--EERKLFIGMLSKRCNETDVRTMFAPFGQIEECT VLREQNGTSKGCAFITYASKQCAQNCIKAMHHSQTMEGCRYPVVVKFADTQKEKEMKKLQ QVN------FLAGGFGGVCVVLSGHPLDTMKVRLQTMPTLYTGTFDCAKKIFMKEGPRGF YKGMAAPLIFAVSFFGFNV-GKSIQVAGVFSTVIMAPGERIKCLLQVCGKQLYREGGIRS IYRGTAATLLRDMPASGMYFMSYEWLQNLLTPEGHSRKDLSPRTLFAGGMAGIFNWAVAI PPDVLKSRLQIREEGIMSLYKGFTPVMLRAFPANAACFLGYEVAMKFLNDSGNEFSRLMQ SVGNNVQKITQNVANLQRMISQIGTNQDSPELRDKLHQIQHYTNQLAKDTSKMLKDMAHL NSEQRQRKVQRERLQDEFATALKNFQTTQRQATDKEKASLECVDMQLLREREDAIRQLEH DIMDVNDIFKDLGTLVHEQGEVIDSIEAHVDQIHVEQGTTQLQKAREYQSKSRRKKCIII IIILVIL------------MVNVMKGILVECDPAMKQFLLHLDDTNGLGKKFVIQDLDET HIFIAADILPTLSARIDDLMDKLHFPMG-KKDKAPTPQEAIQRLRETEEMLQKKSDFLEK KVSQELQVAKKRVALQALKRKKRYEKQLQQIDGTLSTIEFQREALENASTNTEVLKVMGD AAKALKAAHQNMDVDKVHDLMDDVAEQQEIANEIAEAISNPVGFGQDVDEDD-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------VIKG SELQLPFQACLKVEKFGDLILKATEPQMVLFNLYDDWLKTISSYTAFSRLILILRALHVN NDRTKLVLKPDKTTITEAHHIWPTLSDEEWMKVEGQLKDLIMADYGKKNNVNIASLTQSE IRDIILGMEISAPSAQRQQIAEIEKQTKEQSQLTATTTKTTNKHGDEIITSTTSNYETAT FASKTEWRVRAISATNLHLRTNHIYVSSDDIKETGYTYILPKNVLKKFIIISDLRAQISG YLYGVSPPDNPQVKEIRCIVMPPQWGTHQTVHLPNVLPGHEYLKEMEPLGWIHTQPNELP QLSPQDITTHAKVMADNPVWDGEKTIVITCSFTPGSCSLTAYKLTPSGFEWGKQNKDTGN NPKGYLPSHYEKVQMLLSDRFLGFFMTPSHGSWNYNFMGVRHDPNMKYELQLSNPKEFYH EVHRPSHFLNFSSLEDGADREDLYLTTEATRPNLNINKNTKVICQGFTGKQGTFHSQQAI EYGTNMVGGVSPGKGGKTHLGLPVFNSVKEAKDATGANATVIYVPPRFAAAAVEEAIDAE IGLAVVITEGIPQQDMVKVKHKLLRQNKTRVIGPNCPGIIKPGECKIGIMPGHIHMPGKI GIVSRSGTLTYEAVHQTTQVGLGQTLCVGIGGDPFNGTNFIDCLDVFLKDPATEGILLIG EIGGQAEEKAAAFLTEHNGPNRKPVASFIAGLTAPPGRRMGHAGAIIAGGKGGAKEKIQA LQDANVEVTMSPAQMGKAILDAMKAMDKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--RFVEIGRVAYIA FGPDAGKLVVIIDVLDQNRALVDGPCTGVGRKQINLKQLHLTKFVMLTRSARAKTIVKVW EKEEITKKWNETT--------SKRADLTDFDRFKLMKAKQARNRLVNVQFGK------KV CPLLLRVFCSTGRHHILAEYSRGNTPANELQIYTWMDATLKEITGLVKEVNADARKKGTY FDFGIVYPIPNSSAYRLREVGSTCSGRKGADDNITLLQKKFQIGDYLDIAITPPR----- -----------------GPHLIIVPKSTLQNWMNEVKRWVPSLKAVCLIGDQEKRTALIR DVILPGEWDVCVTSYEMCIREKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFRTANR LLLTGTPLQNNLHELWALLNFLLPDVFNSSDDFDSWFNSNN-LDNEALVKKLHEVLRPFL LRRIKNDVEKSLLPKIETKIYIGLSKMQREWYTKILMKDIDIVNGAGKCDKMRLLNILMQ LRKCTNHPYLFDGAEPGPPYTTDKHLVDNCGKMVLLDKLLERLKQEGSRVLVFSQMTRML DILEDYCCWRQWEYCRLDGQTPHEERQESIDAYNAPNSSKFIFMLSTRAGGLGINLSTAD IVVLYDSDWNPQVDLQAMDRAHRIGQKKQVKVFRFLTEHTVEERIVEKAEMKLKLDNVVI QQGRLVDAAA-KEVLTMIRHGAQQVFASKDSAITDENIEEILQKGRAKTEELKKKIDGLG ESSLRTFTMDTEDRSVYQFEGEDYRDKQKMVGLG-WIEPPKRERKANYAVDAYFREALRV SEPKAPRAPRPPKQPNVQDFQFYPPRLFEILDKEIYFYRKSIGYRVPRDPDLGADAVKVQ KEEQRKIDEAELLTEEELAEKEELLKGFNTWNKRDFNQFVKANEKYGRDDLESISKEIEG KAPEEVMAYSSTFWERCNELTDIERIMAQIERGEAKIQRRISIKKALDAKMARYKAPFHQ LRIQYGTNKGKNYTEEEDRFLICMLHKLGFDKENVYDELRAAVRQAPQFRFDWFIKSRTA MELQRRCNTLITLIERENMELEEKEKKDSKKEIKTSWADQVEIGEDEALPSSTEEFNEKS GTKIISEYKYNEDGKKVKVVKTYKIEHRKVSKSIAKRKLWKKFGDAANDPPGPNPSNTYE EILMQFVHGKEQ-DEDPLAKLKVTCRICKGDHWTTRCPYKDTLAPLQDILPKPGKYVPPS MRDGGNRRGESMQSDESATIRVTNLSEDTREADLQELFRPFGAIQRIYLAKDKNTGQSKG FAFINFHRKEDAARAIAGVSGFGYDHLILNVEWAKPSMSETYDFLFKFLVIGSAGTGKSC ILHQFIEGKFKQDSNHTIGVEFGSKVVNVGGKSVKLQIWDTAGQERFRSVTRSYYRGAAG ALLVYDITSRETYNALTNWLTDARTLASPNIVIVLVGNKKDLEAEREVTFLEASRFAQEN ELMFLETSALTGENVEETFLKCAKSILAKIESGELDPERMGSGIQYGDASLRRLQQKKTD CSC----SSSKKLDTSQWPLLLKNFDKLNVRTAHYTPIPNGCSPLKRPIEEYVKSGFINL DKPANPSSHEVVAWIKRILRVDKTGHSGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYV CIFRLHSAVDDRKKILQAIERLTGALFQMPPLISAVKRQLRIRTIYESKMLEYDEKRNMG ILWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGIQSEKDGLVTMHDVLDAQWLFD NRKDETYLRRVIKPLEALLTSHKRIIMKDSSVNAVCYGAKIMLPGVLRYDDGIEIGDEIV IVTTKGEAIALAIAQMTTAVIATCDHGIVAKIKRVIMERDTYPRKWGMGPVASRKKSMIQ QGLLDKYGKPNEKTPANWREGYRDYSVTPKRKHAAPSTDKKKKKKKKKMAEADWDRKKAP KSSQLKSQQALNAAQRKGLQIETSKKFTASSNKQHSANKNTAKLDRETEELHHDKLGMDV GRLIQQGRQAKEMTQKDLATKINEKPQVVNDYEAGRAIPNQQILGKLERALGMKLRGKEK GQAM---MLKPKALTQVLSQANTGGIQSTLLLNSEGALLAFSGYGDKDARVTAAIASNIW AAYEKNGKIAFNEDGLQLVLMECQDGKVAITKVANLLLCIYAKDNVGLGILKEKAAALAS YLEEPLTHVAAS---------------------------------GKKRYTDYEVRMKTN LPVFKVKESSVRRRYSDFDWLRGELERDSKIVVPPLPGKAWSRQLPFRGDD--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ETVKGRGIIGLEPVLSKSQPVFQWTSHSSLQTPRGN MWGVFKMEREDGSDFQVNIPTISLRSENDD-MATAKGANTYNRQNWEESDFPILCQTCLG DNPYIRMTKEKYGKECKICARPFTVFRWNPGARMRFKKTEVCQTCSKLKNICQTCLLDLE YGLPVQVRDAALKIAEEMPKSDVNKEFYTQNMERELANSDGTNPVGALGKAMAPSDMLLK LARTTPYYKRNRPHICSFWVKGECKRGEECPYRHEKPTDPDDPLADQNIKDRYYGTNDPV ADKLLERYNAMPKLEPPDDMDVFLMVRRKKMTIFMDAKESTTVLELKKMVQGIAKRAPED IKLFKEHKTLGDCGFTSSTARAQAPASIGMVFREFEALEIAPLSTPPELPDVMKPQETSS SHQPEHVYRYNACLLRERFDKNKDIDVREAKRILIAGEQELQTKAHPQPYKFPYSPGGVA HGRDMILPDWYLDIWHPLERAQYPEYFARREIRKKEFIERWEKQYGSS---DVSLTDKLG QGTFGVVYRGRHAKKGDVVAVKQCEIQSDQYGF--MAMKEIKNFQQLNHPNIVKLRDFHY SRNAFWMVMEFCDADLVKYTKTTNPD--MDSKI--NIMYQCASAIAFMHTRKVVHRDIKP ANIMMDGKAVVKVTDFGLSKVV-------------------------------------- --------------------------------------GVSSLPDYKPTFPNWIENTLST SVDETGLDLLAKTLIYDPAQRISAKATLQHPYFASRILNRIGQLGIGLALAGGVVNTALY NVDGGHRAVIFDRFSGVRDTVVGEGTHFLIPWVQKPIIFDIRSRPRSVPTVTGSKDLQNV NITLRILFRPQPTSLPNIFKTLGVDYDERVLPSVVNEVLKAVVAEFDASELITQRELVSD KVRQDLTLRAAHFGFILDDISITHLTFGREFTEAVELKQVAQQDAERARYVVEKEEQKKI AAIIRAEGDSQGASLLAQAFGGAGEGLVELRKIEAAEDIAYQLSQSPNVVYLPQGQQTLL ALP----------------------------------RREFRHMAIDVKMTAKNTLVVEK WFGIKKELAAVRTVCSHIQNMIKGVTKGFRYKMRSVYAHFPINVVISNNDTSVDIRNFLG EKFLRKVNMLQGVTCKSS-GQKDEFIIEGNDIELVSKSAALIQQSTTVKRKDIRKFLDGV YVSEKSTVVQDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXKKFAEMKRMINLKDSRIQKKYREKKKKKKSDPQNMKIRELPQSSSALFFQYNTQLGPP YHVLVDTNFINFSIKNKLDIVKAMMDCLYAKCIPYITDCVMAELEKLGSKYRVALRIAKD ERFQRLPCMHKGTYADDCLVQRVTQHKCYIVGTCDKDLKRRIRKIPGVPIMYLAQHRYSI ERMPDAFGAPKMSFSSDEVNFLVYRYLQESGFAHSAYTFGIESHISQSNINGALVPPAAL LSIIQKGLQYTEAEISIGEDGAERVIESLSLIDAVMPDVVEQRKQTAAKAANGDDTNEPM EIDGNIEIPSNKATVLRGHESEVFICAWNPTNDLLASGSGDSTARIWNMNDNSNSNQLVL RHCIQKGGTEVPSNKDVTSLDWNCDGTLLATGSYDGFARIWSTDGRLVSTLGQHKGPIFA LKWNKKGNYILSAGVDKTTIIWDASSGHCTQQFAFHSAPALDVDWQSNTSFASCSTDQCI HVCKLGADKPIKTFQGHTNEVNAIKWDPQGTLLASCSDDMTLKIWSLKHDSCVHDLQAHN KEIYTIKWSPTGPGTNNPNAPLILASASFDSTVRLWDVERGVCIHTLTKHQEPVYSVAFS PDGKFLASGSFDKCVHIWNVQTGALVHSYRGTGGIFEVCWNHRGDKVGASASDGSVFVLD LRKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XX-LELLSDQGFRIDGRKPHELRRIQCRMGVFSQADGSAYLEQGNTKVLAAVYGPHECK- AKSKHDKALINCQYSMATFSTGERKRRPRGDKKSIEMSQHLKQTFEAAILTHLYPKSQID IYVEVLQADGGNYCTSVNAATLAIIDAGIPIKDYVCACSSSFINETPVVDINYLEESSGP ELIVSTLPKSDQMVFVEMNGRLHEDHLSKVIDTAVKGCRDVHDILDRAVRDXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXSHQFRLFHSDVKVPNFDAYRRTSVKESRKAFTYLLMGAGAVPAAYAAKT VVTQFVSSMSATADVLALAKIEVKLTDIPEGKNATFKWRNKPLFIRHRPQEEIDREADVD LTSLRDPQHDTERVEKPEWLILLGVCTHLGCVPIANAGDFGGYYCPCHGSHYDASGRIRK GPAPLNLEVPVYTFPDDDTVIVGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXX------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVY EMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVN DIKGHKWFATTDWIAIYQKKVDAPFIPKCKGPGDPSNFDDYEEEPLRISSTEKCAKEFAD F-----ILILIIYIITALLGEGLTWVLVYRTEKYKKLKAEVEKQSKKLEKQKENIGDPSE RSQKKKLERQEEKLKNNNRDLSMVKMKSMFAIGFAFTALLSMFNSIFDGRVVAKLPFTPI SWIQGISHRNLLGEDYTDCSFIFLYILCTMSIRQNIQKLLGFAPSRAANKQGTGLF---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------IACLQYRDRLVVSGSSDNTIRLWDIECGACL RVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLAAALDPRSPPGTLCIRTLVEHSGLVF RLQ--------------------------------------------------------- ----------------------KLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKS FDNIRNWIRNIEEHASSDVERMVLGNKCDMDDKRQVSKEKGEALAIEYGIKFLETSAKAN IKVEEAFYTLARDIKAKMDRKL------------IRKIKKLIKSLEAARGNGTSMISLII PPKDQISRVAKMLADEFGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVIYCGT IMTEEGKEKKVNIDFEPFRPINTSLYLCDNKFHTEALSALLADDNKFGFIIMDGNGALFG TLSGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAETAVQMYITNDKP NVAGLVLAGSADFKTELSQSDMFDQRLQAKILKIVDVSYGGENGFNQAIELAAESLANVK FIQEKKLIGKYFDEISQDTG-------------------------------YVLKNHQSD ENRILFLRPEQEKDKTYFTDKVSGVELELVESMPLLEWFANNYKTFGACLEIITDKSQEG AQFVKGFGGIGGILRYQVDFQSMEPLDDLGDDFDLDDY----------KRNKEDEKFVQT IMDANAQSHKLYIMDARPSVNAVANKARGGGYESEDAYQNAELVFMDIHNIHVMRESLRK LKDICFPTIDDSHWLSNIESTHWLE----------------------------------- -----------------RGFEVLIEKEWLSFGHKFAQRIGHGEDKHSDADRSPVFLQFID CVWQITTQFPNAFEFNEHFLITILDHLYSCLFGTFLFN---------------------- -----------QHVIFPVASMRRIELWTGYYLRWNPTMRPQEPVHLRNRELLMLKSQLQK KVQELQRQLNEK----KPFIPHVPFDLAQCETAFTRAKTATDEKPLSEAVLKRAQELTPP STEQTAVLNLVTKISTVLDNLVINPTSFEAAQLEEVRQVGSHKKGTMMAGHTVADVVVIL KTLPTVEAVEALGRKVIEDVKQSDPHEVLSMLMHEGGLEISSADATVKVLITTIPPNLKK LDPELHLDGKIMQGHLAAIRHARWFEENAVHSSIKALIRLIRDLKNRFEGFQPLTPWIID LLAHYAIVNNPQRQPLSLHVAFRRALQLLAAGFFLPGSAGIIDPCEQGTVRIHTVMTLEE QDQVCYTAQTLLRVLAHGGFRQIMGLEGSSRIASEMSVWEGVVVTPSDRAYEKIEEVIRL IEQYLKENNLLRTLSILQEESGISLNTVDSVDSFVSDINNGHWDTVLQAIQSLKLPDQKL IDLYEQIVLELIELRELGAARSLLRQTDPMIMMKQQYPDRYVHLENMLARSYFDPREAYP EGQSKERRRNAIATALSGEVNVVPPSRLLALLGQALKWQQHQGLLPPGTSIDVFRGKAAV REQEDEKYPTQLSKTIKFGQKAHVECSRFSPDGQYLVSGSVDGFIEVWNFTTGKIRKDLK YQAQDNYMMMDEAVLCMCFSRDSEMLSTGSQDGKIKVWKMTTGQCLRRFERAHTKGVTSI SFSKDNSQLLSSSFDQTIRIHGLKSGKTLKEFRGHTSFVNDCVFSPDGHQVISASSDGTI KIWNVKSTECTNTFKSLGGTAGSDITVHSVHSLPRNTEQFIVCNRSNTVAIMNFQGQIVR SFSSGKREGGDFVCACVSPRGEWIYCVGEDMVLYCFSTTTGKLERTLTVHEKDVIGIVHH PHNNLVSTYGEDGLLKLWKPMSKLVQRVPQMAEFAKPRLQTFWKYARVELKPPSEFPQIS ESVSNIAKAMTGKWKNMTVKEVTLIGVEIAGWFIIGECIGKGSLVGYNIPG--------- ----------------------RAVFLQRRSRELLDNDELQNLWFLLDKYHTPPLVGEEQ MINFEDFLKVSKEAGQKCKPFFSAAVFGKLLQTDPYGRISIMQFFNYVMRKVWLHQTRIG LSLYDVAGQGYLKESDLENYILELIPTLP------------------------------- ------------------------------SNWFSAPSALRVYGQYLNLDKDHNGMLSKD ELSRYGTGTLTSVFLDRVFQECLTYDGEMDYKTYLDFVLALENRKESQALQYL------- ------------------------------------------------------------ ---------------------AEIVRGQVFDVGPRYTNLAYIGEGAYGMVVSAIDHATKN KVAIKKISPFEHQTYCQRTLREIKILTRFKHENIINI----------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------ATYDKNSPTWNALARVAMLCNRATF KTGQEGVPILKKECNGDASESALLKAVELSIGNVEKYRAANPKVCEIPFNSTNKYQVSVH PNDPSYLLVMKGAPERILDRCSSILINGEEHAMTEEWREAFNQAYLELGGLGERVLGFCD YTLPSEEFPVGYVFDSDEENFPLTGLRFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVT GDHPITAKAIAKGVGIISEGNETVEDIAARLGIPVSEVNPRDAKACVVHGSDLRDMTPAQ IDEILANHPEIVFARTSPQQKLIIVEGCQRQGQIVAVTGDGVNDSPALKKADIGVAMGIA GSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLLFIIAD VPLPLGTITILCIDLGTDLVPAISLAYEQAESDIMKRMPRDPLHDKLVNQRLISMAYGQI GMIQASAGFFVYFVIMSENGFWPSRLFGLRKPWDSKGVNDLEDSYGQEWTYAQRKVLEFT CHTAFFASIVIVQWADLMICKTRRNSILHQGMMNHHMTFGLFFETTLAAFLAYCPGLDKG LRMYPLRWTWWIAPMPFSVAIFVYDETRKYLLRKNPGGWIETETYYSFKKLPSSKKFLAR LATGGAGLGLAIHELILHPPQFPWSHNGPMSAIDHESARRGYQVYKQVCAACHSMHFMHY RNLIGSVMTEEEAKAEAAEQLITDGPNEQGDMFERPGKLADKFPNPYANDEAGKAANNGA LPPDLSLISLARHGGEDYIFSLLTGYCDAPAGFDLQEGQHYNPYFTGGAISMAQALYNEI IEYEDGTPATQSQLAKDVSTFLRLAAEPEHDTRKRMALKVILVFFIPVTVYLKRHKWISV KSRKIT------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------ESHIGVAHRLLQEIPNSHI LDQYRNASNPLAHYDGTGEEILTQCDGNVDMVVLGAGTGGTLTGVARKVKEKCPNCKIIG VDPFGSILAEPESITGYEVEGTGYDFIPTVCERKFVDK---------------------- ------------------------------------------------------MSDMDS DEEQGPYLGAYEGERNEREERHGHGKATLPNGDTYEGVYENGKRHGYGTYRFKNGARYIG EWLKNKKHGQGTFIYPDGSKYEGSWVDDQRCGSGKYFYVNADTYDGEWQNHVRHGQGCYL YADTGTKYQGTWKDGKREGHGELIHANHKYVGTFKEDRPDGRGKYVFDIGCQQHGEY--- ------------------------------FLAMDSHKCVGAIVCKLDLHKKIVRRGYIA MLAVDKDYRRRKIGSHLVQKAIRAMIADDCDEVVLETEITNKGALTLYENLGFVRDKRLF RYYLNGVDALRLKLWLREIDGLMFHLPSNGKKCLKEEIHKDVLVTGEYEISDNPAQKVHL KVIDSKGHILYQKEDVDKGKFAFTTEEYDMFEVCFETVLQQGAGAVQTSVFLNMKHGVEA KNYGDMAKAEKLKPLEVELKKLEDLSESIVKDFAYMRAREEEMRDTNESTHSRVLYFSIF SMLCLLGLATWQVLYLRRFFKAKKLIE--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------DSLGHFQSIVIKSIHRKRMPVREVRGGQTASFALKKSHIRKGMVMVSPKL EPKACWEFEGEILVLHHPTTIAIRYQAMVHVGSVRQTATIISMSQQHLRTGDKAIVRFRF IKNPEFLKPDVRMVFREGRTKAVGTVSKLYPHVTANTRQIRAQKKAAE------------ ------------------------------------------------------------ --------------------------------GHTKSVECLAFSFDSQICSGSWDKSAIL WDMKKIFEGHENLVQSVAFSQSGQFLATGSWDHTVRLWTDKVQILKGHKGNIHAVAFSRE -GMLASGSWDKTIRLWNPRNG--------------------------------------- FVLSGHQGWVQAVAFSSDSLMLASAAEEDDVRVWDCVQGNCVKVLDGQTSTVQNCGFAPG GAVMAAGASTTTLAL--------------------------------------------- ------------------------------------------------------------ ---------ATESNILKELIKPPNILRTIADTVTGKSSTVSDTLPTGQLSNVPWRRMGVK YTNNEAYFDLVEEID--------------------------------------------- ------------------------------------------------------------ -----TMGKTVEDLMIEIPFSKSVLNVTLTPSQGKYSFDPVSKIMTWDVGKIDTTKLPNI KGQINLVTGASPP----------------------------------------------- ----MATYCKPATRYATSDWFTSNYTISTNAERQRTASHDTRQEARFLRNETDNKTKWDQ IDNNTRLADRIDIIRKWKDILEKTLADTDKEIADLSEAKEQTEVQLESMNLPTEVNIENL VTREGRQQIDVVEDEVEDQLHKEQEVIDGIKKQLQTKIDESFEQLCTLQEARQQLLADLQ DKNVALGIDVDQYNLTEESPGISYKPDPLRVPKGSTTPQNWEDFSRYNKERAEAEMDASR RLREAIHHTLQQTANDLKSQKTASEYAYRKRMHEMQRAIGELNWQKQQTEEEIAELEEDI RRLVDSIRAKINPSKLAQTRLENRTYRPNVELCRDNVQYGLTDEVKQVEASKKSLEEKLK QAQHALDGLEQNLHRINKDLQCKMNSLKLDEDCMKSRDKLERNMGLTGITNLKDRVADLI PQQQKAIKEFRAKHNNTVVGDVTVDKVYGGMRGILGLVTETSVLDPEEGIRFRGYSIPEC QKLLPKAPGGEEPLPEALFWLLVTGEVPTQQQVDAISQEWNKRAALPGHVVSMLNSFPSN LHPMAQFSAAIVACNSESHFVKAYTEGVKKTLYWEHVYEDAMDMIAKLPTIAAIIYRNLY HEGTRVAVIDDSKDWSANFTAMLGYEDPMFTELMRLYLTIHSDHEGGNVSAHTCHLVGSA LSDPYLSFGAGMCGLAGPLHGLANQEVLLFLTEMKWTEDQIKEYVWKTLNSGVVIPGYGH AVLRKTDPRYTCQREFAQKHLPDDPMFKLVSDNYKVIPEILLELGKVKNPWPNVDAHSGV LLQFYGMKEMNYYTVLFGVSRALGCMSSMIWDRALGLPIERPKSISTEKLIAMV-MPFVP PKQEKCTTCGKSVYAAERMEAGGNIYHKICFKCVECSMKLQLNNYSQNQGRLYCKNDFQK CVTSQNTQVDQLFVHRDTTDNHPDVKFEFTPENKKRADVIIGNYPVGHEAAAVIPLLDIA QRQNGWLPISAMHYVAEYLKMPRMRVYEVATFYTMFNRNPVGKYHVQICTTTPCMLGGIG SDRILSVIKEKLGIEVGETTANKMFTLTEVECLGACVNAPMVQINDNYYEDLTEEDMAEI LDDINAGKTPKAGPRSGQDNRFASEPKTGLTSLTTPHPGPGFKCRPDLXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---KFMQIAEPKKGVHYPQKD VCDGWPLEYCEYHPNYEKAKAWMEDNLTDDMKAMYLKRQKRGGKGQIKTKKKDTPKGICL SRASRGKKKYMTVVTGLATYGVDLKVASKFFGSKFACGSSVTGDDEIVIQGDVKDDLFDI IPEKWADISEDDIDDLGDMKR--------------------------------------- ------------------------------DCGKLQTLDILLRKLKSGHHRVLIFTQMTR MLDVLEAFLNYHGHRYLRLDGTTKVEQRQALMERFNADKRIFVFILSTRSGGLGVNLTGA DTVIFYDSDWNPTMDAQAQDRCHRIGQTRDVHIYRLISEKTIEENILKKANQKRLLSDVT IEGGNFTTAFFRQNTIQELFQEPSGLD--MSLETVPNDLRHLRACLLCSLVKTLEQFEND GCDNCEEFLHLKNNRDAVYEATSSSFDGMIAMMGPDESWVAKWQRINRFAKGCYAVSVTG RLPPGIVRELKSKGIHYRSRDTS------------------------------------- ------------------------------------------------------------ -----------------------TTQGLDGLSERLAQYKKDGAGFCKWRCVLKIQSHTPS YQAMLENANVLARYASICQQNGLVPIVEPEVLPDGE------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------DESTKGIPEFWLTIMKNV DMLADMVQDQDEEILKHLEDIKVKFQMGFTLEFYFTANDYFSNEVLTKEYTMRAEPDPDD PFGFEGPEIIKCKGCTIDWKKGKNVTVKVVKKTQKHKGRGTKRTVTKTVQNDSFFNFFSP PEVPDEEPDEDTEALLAADFEIGHYIRERIVPRAVLYFTGEALEDDDDDDDEYDEIILLK EGTDTTQGTPQIVSNINACQAIVDAVRTTLGPRGMDKLIVGQGGNATISNDGATIMKLLD IVHPAAKTLVDIAKSQDAEVGDGTTSVVLLAGEFLKQAKPYIEENVHPQIILRSFRKATN LAIKKIKEIAVSIKNDKNEQRKLLEKCAATALSSKLVARQKDFFATMVVDAVMLLDELLP LNMIGMKKVQGGALEDTKLIPGVAFKKTFSYAGFEMQRKKYKNPQIALLNIELELKAERA NAEIRVDNVEEYQAVVDAEWSILYDKLDKIHQSGAKVVLSKLPIGDVATQYFADRDMFCA GRVPDEDLKRTMQACGGSIQTTVANLMLGTCGGFEEVQIGGERFNLFEDCPKAKTCTIIM RGGAEQFMEETERSLHDAIMIVRRAIKNDTVVAGGGAIEMELSKYLRDYSRTIPGKEQLL IGAMARALEVIPRQLCDNAGFDATNILNKLRQKHAGTWYGVDILSEDITDNFVSCVWEPS VVKINALTAASEAACLILSVDETIKNPQAEQGGPGAGRGRGRPM---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------EKARKPTDDEKNFNPFIALRQARATQKLHGIRAKK- ------------------------------------------------------------ -------------------------------------ARQDKKDKSPISAKLVANMLSVA GADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENIPEWRNSIIVSPDAGGAKRVT SIADKLNVDFALIHKERKKANEVASMVLVGDVKDKVAILVDDMADTCGTFCQAAERLKSG GAAKVYAICTHGIFSGPAISRLNASEFECVVSTNTLPQGKSMINCDKLQCIDV------- -------------------LGCRFYEHRFPEIEDVVMVNVREIQEMGAYVHLLEYNNIEG MILLSELSRRRIRSINKLIRVGRSECVVVIRVDKDKGYIDLSKRRVSPEEVVKCEEKFAN GRCVNSILRHVGELLGYDTDEQLEELYQKTAWHFDRKYGKTGSSFEAFKHAVTNPEILDE CDIDDQTKKVLITNIKRRLTPQAVKIRADLEVVCYGYEGIDAVKNSLRAGLNFSTEDMPI KINLIAPPLYVMTTRTLEKADGMARGQQKIQSQQKNAAKKAAQAPTQKEYAQKALNHKCS VCMAQMPDAKTYKQHFENKHPKAPLPADLIDV-----------------PKGHCAACSKP IVGQVITALGRIWHPEHFMCSHCKSELGTRNFFERDGLPFCERDYHMLFSPRCASCNGPI LDKCITALEKSWHPEHFVCAHCKRPFGEDGFHEREGLAYCRDDYFEMFAPKCGGCNRPIM DNYISALNKQWHPQCFVCWECQQPFGSSSFFDHDGFPFCETHYHAKRGSLCAGCQKPITG RCITAMYKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCHPCFVKLFMRPLTEDETKILFE KLSKYIGENIKLLIDRPDGTYCFRLHKDRIYYINEELMKKAGNIARENLLSFGTCFGKMT KTKKFKLHITALDFLAPYAKYKVWVKPSAEQQFLYGHHVMKSGLGRITENTSQYQGVVVY SMNDLPLGFGVSAKSTQECRHSDPMTLICFHQADIGEYIRSEETLASNRKFFVGGNWKMN GTKSSIDGIIKFLNDNNENTEVVVAPPAIYLEYVRQKLIGVAAQNCYKAEKGAFTGDIST LMIKDVGCGWVILGHSERRHVFGESDQLVGEKVKFALSSGLSVIPCIGEKLEEREAGKTT EVCFRQMKASDWTNVVLAYEPVWAIGTGKTATPEQAQEVHAQLRKWLSDNVSADVAKSVR ILYGGSVTSANCKDLAAKEDIDGFLVGGASLKPDFIDIINAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------DNPLENLNLAFDIAEKHLDIPKMLDAEDMVNSVKPDERSVMAYVSSYYHAFSG AQQAETAANRICKVLKVNQENERLMEEYERLASDLLEWIRRTTPWLENRTTDNTLPGTQR KLEEFRDYRRQHKPPKLEDKAKLETTFNTLQTRLRLSNRPAYLPTEGKMVGDIANAWKGL ERAEKGFEEWLLSELQRLERLDHLAKKFKHKCDIHEEWAYGKEDMLQAQDFKQCRLNELK ALKKKHEAFESDLAAHQDRVEQIAAIAQELNALDYHDSPAVNARCQRICDQWDLLGTLTQ QRRNALEEAEKILERIDQLHLEFAKRAAPFNNWMDGAKEDLVDMFIVHTTEEIQGLIDAH EQFKGTLGEADKEYQAIIALGNEVVRLAQQYGISGATDNPYTTLSPQDIGHKWSEVRQLV PDRDTTLQTEMIRQQNNERLRRQFAQKANMVGQWVERHLDMTASVGVQKGSLEDHLNKLR GIEKEVQSFRPNIDELERYNQDIQEAMIFENRHTPYTMETLRVGWEQLVTSVARASNEVE NQILTRDSKGISNEQMDEFRKSYFHFDKNRTRRLEPKEFKACLVSLGYNIRDDRQGEADF QRIMSIVDPNHTGFVTFDAFLDFMTRETADTDTAEQVMQSFRILSGDKPYITPDVLRREL PPDQAEYCIARMAPYTGYDAVPGALDYTSFSTALYGESDL-------------------- ---------------ITAALPTVQHALENGAKSVVLMSHLGRPDGRKQGKFSLKPVAEEL KSLLKRDITFLNDCVGDEVEKACADPASGSVILLENLRFHIEEEGKGVNEAGEKVKADKE AVEKF------------------------------------------------------- ---------------------------------------------------LYDEEGAKI VQKLMDKAKANNVNIHLPVDFVTGSKFAEDAQVGSATVQSGIQGDALGLDIGSETVQKFT EVIGKANTIVWNGPPGVFE------GTKAMMDAVVHATEKGSTSIIGGGDTATCCAKYGT EDKVSHVSTGGGASLELLEGKSLPGVAALSDAMTGIPPKSWQPSNVTINTTMGELVVELY WKHAPNTCRNFAELARRGYYNGTKFHRIIGDFMIQGGDPTGTGRGGASIYGKEFEDEIHQ DLKHTGAGILSMANSGPDSNGSQFFISLAPTQWLDGKHTIFGRLSSGMSVVNRIGMVETD NSDKPLEDIKIVKRRSRSRDKKRSRSREKRKKPYKYWDVPPPGFEHIEPMQYKAMQAAIP FAGSAISRQARRLYVGNIPFGVTENIMMDFFNNQFKLSGLAQAEGNPVIACQINLDKNFA FLEFRSVDETTAAMAFDGVHFQGQSLKLRRPRDYQPIPGIEEAPNVGVVSTVVQDSINKI FIGGLPNYLNEDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVEQACAGLNGMQLG DKKLIVQRASVGAKNAQQPPVQIQVPGLNVNSMATEVLCLMNMITPEELEDEEEYEDIFE DVKEECGKYGAVKSLEIPRPIKGVEVPGVGKIFVEFNSIVDCQKAQQNLTGRKFANRVVV TSYFNPDRYHRREFFIPMFDRVLVERMAAETKTKSGVLIPEKAQTKVHSATVLAVGEGFK TETGSVVPNNAKVGDRVLLPEFGGTKVLLEDNEYFLFRDSDILGKFERLKTQIPDIKSSL DIVKHLQTKKEDLKTHFQLSDALYVKAKIPPTDKVSLWLGANVMLEYSLDDAEVLLTKNA AKKSLEGVDEDLGFLKDQTTTIEVNMARVYNWDVKRRQ----MADEALAKAGLHFDELNK IRVLDPEIASQTNELKDECKDFLDKMGQFQKIVGTFAGLIDDVAKEVEKEKMKAIGSRNL LKSITKQREAQQQQLQSLITEKKVQLERLRIQYEALMKEEQEQNEFIEQFILQK------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------INEIKLIRDHETNRSHGYGFVTFSDADDAKKALEQLNGF ELAGRPMKVGHVTERTMGSSFFDNDEMDRAGVDLGATGRLQLMAKLAEGTGFQIPQAAAN ALNMNPVQQTPPIATQCFMLSNMFDPQTTSPNWEQEIRDDVIEECNKHGGVLHIYVDKAS PQGNVYVKCPTISAAVASVAALHGRYFAGRVITAAYVPLPNYHQLFQESLRATQLLMPAS EEEDRMPTPPPQHTMKGRSRRGAVSAEVYTEEDAASYVKKVVPKDYKTMAALSKAISKNV LFSHLDENERSDIFDAMFPVHRHGGEIIIQQGDEGDNFYVMDAGEVDVYVNNEYISTIGD GGSFGELALIYGTPRAATIKAKTDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLSKVSIL ENLDKWERLTVSDSLEPVQFEDGQEIVRQGEPGEEFYIIVEGNASVLQRRAENEEQVEVG KLGPSDYFGEIALILDRPRAATVVARSPLKCVKLDRGRFERVLGPCSDILKRNISQYNSF VSLGI------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------SKYASCLKILEGIKDNLLLDMYLAPHVKTLYTQIRNRALC QYFSPYLSADMQKMSTAFNTSVNELEDELMHLILDGQINARIDSHNKILYAKQADQRS-- ------------------------------------------------------------ -----------------VLPHVARFCLISTFLEDGIRMWSQWGEQRDYINVTWSCGWFLS TMFVVVNLFGQLGGCVMVLSRKYVHVACGILFGIIALQTVAYSILWDLKFLMRNLALVGG VILILAETKSEGKSLFAGLPSLGENTHKTYMQLSGRILLVLMFLTLLRFDFSFFHFIQNT VGTALIVLIAVGYKTKLASLVLVAWLTILNFYFNAFWNIPDYKPMRDFLKYDFFQTLSVV GGLLLVVALGPGGYSMDEHKKKW------------------------------------- ------------------------------------------------------------ ------------------------------------------KVTAVHKANIMKLGDGLF LRCCEEVSQLYPKIKFENMIIDNCCMQLVSNPYQFDVMVMPNLYGNIVDNLAAGLVGGAG IVPGESYSSDVAMFEPGARHPFASEAGKDSANPSAILFCASNMLQHMHLER--------- ------------------------------------------------------------ -------------------------------------------------------PIYPD GVALIWNIKFKKSSPEYIFHCQSAVMSTCFAKFHPNLVVGGTYSGQIVLWDNRSSKRTPV QRTPLSAAAHTHPVYCVQVVGTQNAHNLISVSTDGKLCSWSLDMLSAPQDSMELQHKQSK VAATSMSFFSNDVNNYAVGSEEGAVYTGCRHGTKAGINEMFEGHQGPVTGIHTNTVPGQI DFSPYFLSSSFDWTVKLWNAKDPRPLHSFEDNA--------------------------- ------------------------------------------------------------ ------------------LQGHLLKAAQVAEQQVDAEIEKIEKMDEDDFEKLRQKRLQQM KKAQQQKTEWMQLGHGRYEEVPDEKAFFDACKKSKNVVCHFYRDETFRCKIVDKHLALLA TKHMETRFIKINAERSKFLVERL-IVVLPTICLAKDGKTVDYVVGFDDIGGSDEFPTEML EWRIARADVINYSGDLMTPPGQASTKKNLRDDGND------------------------- ---------------------GLYDRSPKTPAVLGLEASGDVTAVGEGVDTLKVGNRVMC VTGVWAEHAAHCFVIPENMPYEEAAAIPVNYITAYHMLFDMGNLRKGRSVLVHMVAGGVG IAATQLIKT--------------------------------------------------- ---EDTNKGISITKSLGKYVLYGTGNVVTGETKSFFSFAKSWWQVDKISPVKLFEENKSV AGFQLRSLLIANKLFDMYNKG----------ALEDVGDAMQKMHDRKNVGKVVIDTSM-T KKQTPSDFLKQIIGRPVVVKLNSGVDYRGVLACLDGYMNIALEHTEEYVNGQLKNKYGDA FIRGNNVLYISTSKRRV------------------------------------------- -------EGGFFKCHMIFPKEYPQKPPKLKFITDIWHPNIDKSGDVCISILHEPGEDQWG YERPEERWVPIHTVETIMMSVISMLADPNDESPANIDAAKEWREGKEEFKKRVARCVRKS QES-----------------------------------------------------FMKG HHHAQFTNIIDIACVDVPTRENRFELVYLFMSLRYNARIKVKTYANELTAVQSITHIFAG ANWFEREIWDMYGVYFANHPDLRRILTDYGFEGHPFRKDFPLSGYVELRYDDEVKRVVAE PLEMTQEFRKFDYDSSWETYPAYRD----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------VMMFCGGAC TQGPGMVVNEELKHVIRSHHDIEKDNAKYMKKACKHYESLANRAAQNGHMIDVYACALDQ VGLHEMKYLANFTGGVLVMGDSFNSSLFKQSFQRVFSKDTRNEFKMAFGATLEIKTSREL KVQGCIGSCVSANQGPSVSDNELGVGGTQAWKMCGLYPNTTYGFYFEVVNQHNAPIPQGG RGCVQ------------------------------------------------------- -----------------------------------------------------------N SPDETSYYRHCLLVEDLAQSLTMIQPILYAYSFNGPPEPVLLDTSSITPDRILLLDTFFH ILIYHGETVAQWRKAKYQELPEYENFKQLLQAPVDDAQEILQTRFPMPRYIDTEHMGSQA RF---------------------------------------------------------- -----------------ACQKKCVPAKFNDSELAKGEAVCIDRCVAKYLDVHERIGKKLT NMSVQDQETMQKLQGTQQPAVIHKVIMVGSGGVGKSALTLQYMYDEFVEDYEPTKADSYR KKVVLDGEEVQIDILDDYVAIRDNYFRSGEGFLCVFSITEKESFDNTSEFREQILRVKGD ENIPFLLVGNKADLEDKRQVTVEEATQRADQWKVPYVETSAKTRANVDKCFFDLMRLIRT KKSDKKKNKKKCVIL--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------CNLPKQARMAFETFRR FYLGKHSGRQLSLQPSLGSADLNAVFYGAKRDETGSLKGVKKHIIQVSSYQMVVLMLFNV KERWSYDEVKSESDIPEKDLLRALQSLALGKVSQRVLSKEPRSKEIEADHMFFVNDGFSS KLHRVKIQTVAAKGETEPERKETRSRVDEDRKHEIEAAIVRIMKARKKMQHNNLVAEVTE QLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVADRINVFPSRMAMTAMKARLK GAQKGHGLLKKKSDALTVRFRQILKKIIETKTLMGEVMKNASFSLAEAKFAMGDFNHLVL QNVNKAQIKVRTKKDNVAGVQLPIFEHYADGSDSYELTGLSRGGQQIDRLKKNFAKAIEL LVQLASLQTSFVTLDEVIKITNRRVNAIEYVIIPRIERTLQYIVSELDESEREEFFRLKK IQEKKKSKKPANLLTDYDEDLLFPIKVCVTGAAGQIAYSLLHPIAKGDVFGPDQPIILTL LDIGPMMSVLEGVVMEMHDCAHPLLTEIIATSEAEVAFKDIDVAILVGAMPRREGMERKD LLKANVKIFKAQGDALNKKAKKSVKVLVVGNPANTNCFICKKYAPDIPSQNFSCLTRLDQ NRAHAQVSQRDTVKNAIIWGNHSSTQFPDCRHAYVVTDALKDDAWLKTDFVKTVQTRGAA VIKARKLSSAMSAAKAICDHIRDWWFGTEEGTFVSMGVVSDGYGIAKDLVYSFPVTINKN WAIVQGLEIDDFARDKMDVTMKELLEEKAGAEESC------------------------- ------------------------------------------GVPQVYYFGPCGKYNALV LELLGPSLEDLFDLCDRKFSLRTVLMIAIQLISRMEYVHSKHLIYRDVK----------- ------------------------------------------------------------ ---------------------------------------------------YLRYVRRLD FFXTPDYQYLIKLFTDLMVKNNWDRDWDFDWTSRQLRHGGSVQVVRSTNAED--SGGQSN TPITQPNEVEVVDETKCCXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXEQQLDCALDLMRRLPPQQIEKNLSDLIDLVPDLCEDLLSSVDQPLKIARD KTHGKDYLLCDYNRDGDSYRSPWSNEYEPPLDNGAMPSERLRKLEVEANTAFDQYREMYF EGGVSSVYLWDLEHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRSAHYKLTST AMLWLQTNKQGSGTMNLGGSLTRQVETDCSVSDS--HIANIGKMVEEMENKIRHTLNEIY FGKTRDIVNGLRSTQPLQRENLKMDLQNALQKRTQFDGDFDEVEEPLDEVEHREEVDVLP ESEAVPPEKRMCTPYMTKYERARVLGTRALQIAMCAPVMVELENETDPLEIAMKELKARK IPMIIRRYLPDGSYEDWGIDELIITDVKQAIKDSATKPAGDTAFNLGRAAVGGASVVGLG ALCYYGLGMSNQLGAIDKAVMWSDLVKHRIRDTYMYFGGSLMFTAIARNPTLIRLVSQNG WKSLVGTIAAMWGSGMLCMGLPYQKGTKQMAWILHSSVIGAVIAPLTLLGGPLMIRAACY TAGIVGGLSTLAICAPSEKFLNMGGPLAMGLGVVFASSIGTWFLPPSTAMGAGLMSVAVY GGLIVFGMFLLYDTQKIIKRAETHSSFDMKPFDPINNAVGVYLDTINIFIRMVMILS--G NRKKMEIVYVYTKKRAEFGRQCNFSDRPAELHVDIVPDATLAENFIERNPVDTGIQCVQE MSEHDVNTERFETDTRGINHVEGGWPKDVNPQEMEQVIRFRKKVEKEEMYTNTVLQLASV MEHTIKQNNAIDIYEIYFDEVDVEEADEAPSAKTINVFRDPNELKRTATHISWYPDGPKK LAIAYSNLDFQGSTADTMESYIWDVENPNKPEMTLKPVSPLVCLEYNPKDSHILVGGQYN GQIAYWDTRKGSQPIEMTPIEHSHRDPAYKVIWLQSKTGTECFSASTDGQVLWWDIRKMG EPTEKLYLDPTKKQDFSKAQGAMALEYEPTIPTKFMVGTEQGSIMSCNRKAKTPAEKIVA IYPGHHGPVYSLQRNPFFPKNFLSVGDWTARIWSEDIRESSIMWTKYHMSYLTDGCWSPV RPSVFFTTKMDGTLDIWDFIFKQNDPTLSLQVCDEPLHSIRVQDSGKLIATGSHSGTTTL LELSDGLCTLQRNEKALVTAMFERETRREKILEARHREMKLKERTKSGWEELLTRIGPIA NPLAPRKLTKKLYKVIKKALRKGVREVQKFVRKGEKGIVVLAGDTNPIEVICHMPCVCEE SGLLYCYTPSKEDLGAACGSKRPTCMVMIKKHEEYDELFKDISEDVQNLPLPIMPLENWE EEGLEKIPNLELAQWKFLLTTGKHKDDSKIRNDILQTLKVDNMAPLYEHTCDEFGWPKDE KLLQQMKSNNETKLKELDNKIEDAEKNLGETEVRDFMLERALHFTRIGDKESALSQFRKC GEKTVTVGFRLDMVFHQLRIGLFYMDHDLIKRNLEKAQSLIDEGGDWDRRNRLKVYRGLY CMAIRDFKTAANLFLDTVATFTSYEIMDYQTFVMYTVFSSMIALDRPDLRKKVIKGSEIL EVLHSLKDIRQFLFSLYDCHYDDFFKCLAEVEERMKYDRYLAPHYRYYVREMRILAYSQL LESYQSLTLEYMANAFGVTIDFIDRELSRFIAAGRLHAKIDKVGGIVETNRPDSKNYQYQ ETIKKGDILLNRLQKLSRVINI-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -GGLILMGGGYYPQDTIQTMAALAAFISSINIGGGFLVTQRMLDMFKRPDDPPEHIYLYG IPAAALIGGYGACYTGAYPDIHNLAYLASSLCCVGALTGLSSQKTSRLGNALGIIGVSSG VIATLGFIKPGPELLTQMAVCMGSGGLIGTVMAKRLEVTDLPQMVALFHSLVGAAAVITC VANYMYEFPHFDTDPAANVTKAVAFLGTFIGGVTFTGSLVAFGKLQGLLKSDPLLLPGRH AMNLSMALANLGALGYFLYDPSTAGMSMLGATAGLSSIMGITLTAAIGGADMPVVITVLN SYSGWALCAEGFMLNNNLMTIVGALIGSSGAILSYIMCKAMNRSLPNVILGGYGTSSYAG GKAMEITGTHTEVNSDNVVEMMSDAENIMIVPGYGLCVAKAQYPIAELVELLRSKGKLVR FGIHPVAGRMPGQLNVLLAEAGVPYDIVNEMDEINDDMPDVDLTLVIGANDTVNSAAEED PNSIIAGMPVIRVWTSGQVVVMKRTLGVGYAAVDNPIFFKENTGMLLGDAKKTCDTLLEK TR----------PPGLEYLAQIDQVIIKQQIELFEVLTGFETNNRYKIFNSMGQQIYYAQ EDTSCMMRMCCGPGRGFTIRITDNNNVEVMRVVRQFKCCAGCCWCAGCAFELSVEAPVGN VIGYARQMCWAPKYGIFDAVATIRGPCCVCNAPCC-GDVEFPVTDQQVAMVAKQWTGVLM EMFTDADTFSIRFPTDMDPNIKATLFGVMFLIDFMFFEKKNNXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-N RSSGLVQRRHVAQEEEDHDSKETRLTLMEEVLLLGLKDREGYTSFWNDCISSGLRGCILI ELTLRGRVELEKTGMRRRSLLNRKVLCKSDTPTGDVLLDEALKHIKETQPADTVQSWIEY LSGETWNPLKLKYQLRNVRERLAKNLVEKGVCTTEKQNFILFDMTTHPLVDSGIKGKLVK KVQDSVLSRWVNDPHRMDKRMLSLIYLAHASDVLENAFAPLSDDDYEVAMKRVRELLDLE FEQESMKEGTNELMWAVITAFSK-KKLTQANEENCEVCVKFMTRFIDSLSAIEKAFKKTC KNTKKDDNRFCYYVGGLEESATGIVGEMAKPVSWGMPADKVCMKLYRKDEQICDLKYEKT IDLATVNLKKLKVKDLKQILSDWDATCRGCTEKSDFIKMIEDLMKKHDPTAW-------- ------------------------------------------------------------ ---------------YFEFGFVIPDSTNTWQSIIEAAPESQMMPAKVLNGNVTIETKFYD GDMLVSTSKVRVFYVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------STAQQKR GYADMAFTFACPAAVNVKQVDVPASTGTFGILPNHVPTLGVLQPGILSVHEDDGSPKQYF VSSGSVSVNEDSSVQILAEEAVLVSDLDPQAVRDGLAKANQELSSEKAKAEAQIEVNCFE AMQRAI-CKYFVTELTTRLDKSAKSKEIIETGHGLEKKKKFKYLTSELRLTEALHEPHIC ENILQYNVHAEREGSLRYAKGMSETFETLHGLVDKGVKVELGMPYELWDKPSAEVTKMHR ACFKLAEEYEDAIETWYYHRQQNLFNYICKQRYLSKMKW------VTSEKDVQRALLAQT EFGKLDVAVSCAGTATAIKTYKVKQDQVFPLEEFNRVLKVNTTGTFNVTCLAARMMSKNE PNKDGSRGVIINTASISAFDGQKGQSAYSASKGAIVGMTLPIARDLAELGIRVNAIAPGL FHTPLLGDLPEKVIQYLGKITPFPSRLGLPDEFGHLVQCIIENPMMNGEVIRLDGALR-R QFHFKINGNKQDTKSQLARDYPVVDHVYDAVVVGAGGAGLRAAFGLADKGFKTACITKLF PTRSHTVAAQGGVNAALGNVEEDRWEYHFFDTVKGSDWLGDQDAIQYMCEEAPQAVIELE NYGMPFSRLENGKIYQRAFGGQSLDYGKGGQAHRACCVADRTGHSLLHTLYGRSLYYDTD YFIEYFAIDLIMEDGQCKGVIALSLEDGNIHRFRCNNTVIATGGFGRSYFSCTGAHTCTG DGNAMVTRAGLSNEDMEFVQFHPTGIYGAGCLITEGCRGEGGYLINSEGERFMERYAPTA KDLASRDVVSRSMTIEIREGRGVGPEKDHAYLQLSHLPPEQLSARLPGISETAHIFAGVD VTRDPVPVLPTVHYNMGGVPTNWKGQAIQTNNVDYVVPGLWAAGEAACVSVHGANRLGAN SLLDLVVFGRACANNIADVNKPGDKVPDIKQDAGEPSVANIDQLRHSNGSAPTAELRLAM QKVMQNNAAVFRDGPTLKEGCEKIDALYQDMNLKVSDRGMVWNSDLVETIELQNLMLCSL QTVHSA------------------------------------------------------ ----------------------------MTALSQEEIISNTKTVVQGLDTLKNEHHQILN SLLNSVKTIKEESTNLQDEKTNRLKKSIEMIELGLGEAQVMMALANHLQHVEAEKQKLRA QVRRLCQENAWLRDELANTQQKLQQSEQKVATLEDHPITADVLSNL-------------- ------------------------------------------------------------ -----------------------------------------------------CQCIMKR GSLQDGIKTAVQALVIRIKVLG-DHLDTGRAYRMLAYLMMRSGQHDEAVRFAQCGLEIYD KIEAPEKYKI-EVKNIIAQAQYK------------------------------------- ------------------------------------------------------------ ---------------------------------------------------LQAGTNKCA SQSMGGVRHVADIRADDMSKEGAGVIGLQAGNKGASQAGMSMGAVRHVSDIRADDMTKEG AGVIGLQAGSNKGASQAGMSMGAVRHVADIRADDMSKEGANVIGLQAGSNKGASQAGMSM GAVRHVADIRADDLTEGSSVIGGQMGYTEGASQKGMSMGAVRHVADIKADDMGGSSIIGL QMGTNKLASQKGMSMGAVRHIADIRADDMASEGIINLQYGTNQGANQQGIKIGGRRNI-- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------RVFSGYIKEVDSKPDSTNWGKKMTFGN LMAEFSNGGGWVHSICFSASGEKLAWVGHDSSISVADATMKLKFLPFTSCLWISENNIVV AGHDCCPMLFNYDGQRLSFVAKVDTSKFSAMKHFQSLDTRSAVVETLHQNTILQLAYYSG DKSNCNRFSTSGSDGQLIIWD--KEIDGYVGFANLPNQVYRKSVKKGFEFTFMVVGESGL GKSTLINSMFLTDLYSAEYPGPSQRIKKTVQVETTQVVLREGGVQLRLTVVDTPGFGDAV DNSNCWQPIISHIENQYDAYLNAESRVNRKVMPDQRVHCCLYFISPNGHGLKPLDVEFMR RLHDKVNIIPLIAKADTMTPDEVREFKKTILNEIAQHKIKIYEFEDDEEARLQKKLKDRV PFAVVGSNTVVDAGGKKVRGRVYPWGVVEVENLEHNDFIALRNMLIRTHMQDLKDVTNNV HYENFRYNKLSSVTKSPLIQMEDEKKEHVSKMKKMEAEMEQVFEMKVKEKMQKLKDSEAD LQRKAEQMKKSLEQQEREVQEKWKIFEKEKATWEEEEEMARRYDSRTTIFSPEGRLYQVE YAMEAIGHAGTCLGILANDGVLLAAERRNTNKLLDEVAYSDKIYKLDKDIACSVAGITSD ANVLTNELRLIAQRYLLQYQEPVPLENMIATICDVKQAYTQFGGKRPFGVSLLYMGWDKH YGFQLYQSDPSGNYGGWKATCIGNNSSAAVSMLKQEYKEGETDLNAALDLSVKVLSKTLD TNKLTPEKVEIATLSRVNGETIIRILPANEVEVAIKKYEAEEAKAEAEKKKDMNEAWERL KSLTIKRQERLFGAHEIQRFNRDADETIMWINEKDNMLSTDDYGRDLASVQALQRKHEGV ERDLAALEEKVKQLGGEAYRLSDVHPDQAEDIRNKQEEIQQNWEKLRTKAGERKQRLDDS YYLQRFLSDYRDLISWIGDTKTIISADDLAKDVAGAEALLERHQEHKGEIDAREDSFRSL AEAGQKLMDSDHFAVKEVEEKLVHLANEKTSLLELWEERRVLYEQCMDLQIFYRDTEQAD AWMGKQEAFLANEDLGDSLDSVEALIKKHEDFEKSLAAQEEKITALEEFANKLIENEHYA ADDVAARKSALLDRRNALYSKSTQRRQLLEESYKLQMFERDCDETKIWINEKLKAASDEG YLDPTNLQGKVQKHENFAAELAANQARVEGVTKNGQELIDSDHYAKDNIQERIDELGTLW QQLVEQSERKGNKLREASDQQQFNRNIDDVEIWLTEIEGQLMSEDYGKDLTSVQNLTKKH SLMEADVGSRQDRVDGIIQATTAFVECNHFDKDNIKAKQVQVVERYQNLFDPMKAKRSKL GDAILLQQLFRDVEDEEDWIREKEPIAASTNRGRDLIGVQNLMKKHQALLTELAGHEPRI NEVSAQGMQMVKQEHFASIDIDEKIKDLEDKWQQLKDKAAKRKEDLEDSLQAQQYFADAN EAESWMREKEPIVGNTDYGKDEDSAEALLKKHEAMVSDLEAYRPVIDQLRDQAQACKQQE APVVDDLGKECVVALYDYTEKSPREVSMKKGDILVLLNSTNKDWWKVEVNDRQGFVPAAY VKKIDSSLTASQSQLADEYTISVRQQQIENQYENLLELGSQRKQKLEESCKAYQLVREAG ELAQWITDKESVALTEEVGDDLDQVEAIQRKFDDYQKDLKANEARLMELNTIAEKLTAMG QTEAAEKIRIQIADLNQRWAALQQVTQERAQTLGSAHEVQRYHRDADETKEWIEEKDNTM NTEDFGHDLSTVQRLQRKHEGLERDLAALNDKVKDLDETANRLMNTHPEQAQSIYEHQKD INEMWNTLTQKADDRKTKLLDSYDLQRFLSDYRDLNSWVSSMMALVSSDELAKDVTGAEA LLERHQEHRLEIDARGGTFTAFEKFGNQLLENNHYNSEEVQEKMRDLAENREALEQAWIA RRAKLDQCLELQLFNRDCEQAETWMAAREATLRDEVDG-ESVESLMKKHEDFDRAINAQE EKIAQLETFADQLIENDHYDGEGIDNKRKQVLDRWQRLKEALLENRAKLGEAQSLQQFSR DVDEMEIWIQEKLQMAMDESYKDPSNIQAKHQKHQAFEAELAANADRIQSVIRMGEKLID NQQCAGSEDAVRERNRKLVEEWEYLTSKSSEKREKLEEANRQRMYTAAVKDLEFWLGEVE HMLETEDYGKDLATVQNLNKKHQLLEADIKAHEDRVRDLNEQADVFIESDLWDVDSIKEK KQSINDRYNNVCDLANQRRSKLDEANNLHQFFRDIDDEEAWIKEKKLLVGSDDFGRDLTS VQNLRKKHKRLEAELSSHEPAIQAVQDTGAKLVESSNLMNDEISERLKGLAQNWDELRDM AALRGQKLDESLAYQQFVANIEEEEAWITEKHHLLSGEDIGDTLAAVQGLLKKHDAFETD FKVHQDRGEEITKDGDKLIAEGNHNAENIRQKCATLEEKLKNLDDDAKRRKAKLVDNSAF LQFIWKTDVVESWIADKETQVHSEDYGRDLSSVQTLLTKQETFDAGLQAFEKEGIQTITA LKDQLVASNHAQTPAIEKRYNDVITRWQKLLSDSDDRKQRLLRLQDQYRQVEDLYLTFAK RASGFNSWFENAEEDLTDPVRCNSVEEIQALREAHEQFKSSLSIAEGDFRQLAELDKQIK SFNVGPNPYTWFTMEALEDTWSNLKKIIRERDEELAREQQRQEENDVLRKQFAQAANAFH QWLTETRSAMMEGTGTLESQLEATKRKASEVRAQRNQLKHIEDLSAAMEERLILDNRYTE HSTVSLAQQWDQLDQLGMRMQHNLEQQIQACNQSGVSEEALREFSMMFKHFDKDKSGKLN HQEFKSCLRALGYDLPMVEEGQRDPDFEAILDSVDPNRDGLVSLQEYMAFMISRETENVQ SAQDVEAAFRALTSGEKPYITAQELFANLTREQADYCITRMKPYEDPKGRIIPDAYDYVG FTTELFINAIQCYQCDSNEDASCPSNRPFDENLNALVDCNSFEAKVPGTFCMKITQQSPG WRAWKKQTRRCGSRSDTGVAWGCRWLYEENGVWKETCYCEDRDGCNTASAIDKDDGENPQ LVSEYVNDIYEYMRELERKEINGRMRGILIDWLVQVHLRFHLLQETLYLTVAIIDRFLQE EVTRNKLQLVGVTSMLIASKYEEMYAPEIGDFEYITDNAYQKSDIRKMECLILKTLEFNL GRPLPLHFLRRNSKAGEVDATKHTLAKYLMELTIVDYDMVNVHPSEIAAAALCMSMKILD WSDTLKYYSKYSENELLPIMKKMANVVLKKLTAIYTKYKSSKFMRISVIPELQSQVVHDL A----------------------------------------------------------- ------------------------------------------------------------ ----------------------------------LLGPQKREQWLQLRSEIEAMTDSWLT LAQKSLSIINSRSSCVNVLVTTTQLVPALAKVVLYGLGGVFNIENVYSATKIGKESCFER IVSRFGRKCTYVVVGDGRDEEAASKQMNWPFWRISNHSDLAALHHALDLGYLTSALSVGG DRTTGQSVRTQNVMAASSIANIVKTSLGPVGLDKMLVDDVGDVTISNDGATILKLLEVEH PAAKVLVELAQLQDEEVGDGTTSVVIVAAELLKNADELVKCKIHPTSIISGYRLACREAC KYIQEHLTMKTDDLGRECIVNAAKTSMSSKIIGPDSEFFSNMVVDAAEAIKTNN-----K YPIKAVNVLKAHGRSSRESVLVKGYALNCTIASQAMVKRVPNAKIACLDFSLQKAKMKLG VQVLVDDPEKLQQIRDRESDITKERIQKILSSGANVIFTTGGIDDLCLKYFVEAGAMAVR RCKKSDLKRIAKATGGQLIVTLANLEGEESFEASFLGSADEVVQERICDDELILIKGTKA RSAASIILRGANDFMVDEMERSIHDALCVVKRVLESKSVVPGGGAVETALSIYLENFATS LSSREQLAIAEFARSLLVIPKQLAVNAAQDS----------------------------- ------------------------------------------------------------ ---EEESGRLLASKVVLNDMLVEGKDTTVEYTIYNVGGSAALNVELNDLSIDTSDFEIVQ GNTHVQWARLAPGSNVSHVVIMKPVKSGTVNFTSATITYSPTAGEKQVGFTSAPGEGFVM NYKEYDRQFSPHVTDWAVFGLMTLPSLGMPLLLWYSSKSRYENSKSKKNSGAAQKDKTEK YKAILEKTEGVKLIIEALVNENVSLVISRQILSDLCGQLSNFNSDTGKELCHYILEKIQP RVISFEEQVAAVRQHLADIYEKETSWKEAANVLVGIPLETAQKQYSSDYKLNTYLKIARL YLEDEDPVQAEAYINRASMLQADSSNAELQIYYKVCYARVLDYRRKFIEAAQRYNELSYK TIVAEEERMTALKNALICTILASAGQQRSRMLATLFKDERCQQLPIYGILEKMYLDRIIK SGELQEFSELLQSHQKAVTSDGSTILDRAVIEHNLLSASKLYNNISFEELGSLLEIPPSK AEKIASQMITEGRMNGSIDQLDSIVHFESREALPNWDKQIQGLCFQVNTIIEKINVAAPD WLAKTMEEQM---------------------------------GETLISSSDDDSIVIYD CQNGTPKRTLNSKKYGVDLIHYTHATNTAIHSSTKVDDTIRYLSLHDNKYIRYFQGHTKK VVTLNMSTI-----------------------QGLMHLPGRPVAAFDPEGLIFAAGINSE SLKLYDLRSFDKGPFATFKLQQDRECDWTTLKFSPDGKLILISTN--------------- -----------------------FVFCGSTDGKIHTWSTETGMKVGVLQGDHSAPVQCVQ FNPKYMMLSTACNSMSFWLPQMDE--LKVEKKGEKQNVGLIQLNRPKALNALCAGLMLEL NQVVESFENDPGVGCIVLTGSDRAFAAGADIKEMQPKSFPAVYTENFLCSWNKLQDCRKP VIAAVNGFALGGGCEVAMMCDIIYAGEKAQFGQPEIILGTIPGAGGTQRLTKAVGKSKAM ELVLTGDKISAHEAEKAGLVSKVFPVDQLVDEALKTAEKIANHSKVIVAMAKEAVNSSYE MPLQEGLKFEKRFFHQTFGTNDRKEGMTAFVEKRPPNFTD >Myzostoma_seymourcollegiorum MSERKAVVKNADMPEEMQQDAVDCATQALEKFNIEKDIAAYIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYIGQVAVLLFKSG----NRSFQTSAVARDIDMAAKYIGAGAATV GVAGSGAGIGTVFGSLVIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLLLFAF- -------------IHKIRITLTSRDVTRLEKVCADLIAGAKNKLLKLKGPVRMPTKVLRI TTRKTPCGEGSKTWDRFQMRIHKRVIDLHSSSDVVKSITSINIEPGVKVDVTL--MDQLI QTLAPAKQFVKDSIRVVNKCTKPDRKEFQKIAIATAIGFAIMGFIGFFVKLIHIPINNII V---QFSKKKTFVGEGVFKAELDEFLKRELAEDGYSGVEVRSTSQRKEIIISATRTQNVL GEKGRRIRELTKAVEKRFNIAEGLVELYAEKVANRGLCAIAQCESLRYKLIGGLAVRRAC YGVLRFIMENGASGCEVVVSGKLRGQRAKSMKFVDGLMIHSGHPANEFVGTAVRHVLLRQ GVLGLKVKIMMPTAVPGK--HAKPLPDQVNILDPKDEPILTEPTSEHVCQK-SKRGRGGS SGAKFRISLGLPVGAVINCADNTGAKNLYIISVAGIGARLNRLPAAASGDMVMATVKKGK PELRKKVMPAVVVRQRKTFRRKDGTFIYFEDNAGVIVSAKGEMKGSVVTGPIAKECADLW PRIASNAGTVRKGKEKKVTLGPQVADGENVFGVAHIFASFNDTFVHVTDLSGKETVARIT GGMKVKADRDEASPYAAMLAAHDVSERCKEIGITALHIKLRATGGNKTKTPGPGAQSALR ALARQGMKIGRIEDVTPIPSDATRKKGGRRGRRL----RRLRTARKLKNHRREQRWHDLT YKKAHLGTRYKCNPFGGASHAKGIVVEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP NDGCLNFIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKGKKERPRS--- -TIRTKKFKTNRLLGRKQMVVDIIHSAH-TPSKTTVKDKLASIYKTNAANIVCFGFQTIF GGGRTSGFALIYDNVEAMKKYEPKYRLIRTGPRKQRKELKNRKKKVRGTAKAKVGAMPRV KKVCRKTYATPRRPFEKERLDQELKLIGEYGLRNKREVWRVKLTLAKIRKAARELLTLDE KDPVRLFNGNALLRRLVRTGVLDELRMKLDFVLGLKIEDFMERRLQTQVFKLGLAKSIHH ARVLIRQRHIRLRKQVVNIPSFIVRLDSQKHIDFSMNSPFSGGPPGRTKRRSNQKGDADG GDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMPLVKDLLNPSTESELKKHKLKRLVQSPNSFFMDVKCPGCYKITTVFSHAQSVVLCV ACSTVLCQPTGGKCRLTDGCSFRKKQ-MVLMNVLADTLKRIQNAEKKAKRQVLIRPTSKV VVKFLTVMMKHNYIGEFEIIDDHRGGKIVVTLNGRLNKCGVISPRFDVALKDIEKWTSNL LPSRQFGYIVLTTSAGILDHEECRRKNTGGKILGFFFMGRMHAPGKGISQSALPYRRSTA SWLKITKEDVIEQIVKYAKKGLTPSQIGVIMRDSVGVAQARYVTGNKILRTLRAAGLAPQ IPEDLYHLIKKAVSMRKHLERNRKDKDGKFRLILVESRIHRLGRYYKRTQVLPPNWKYDS ATASALVAMADITQPKLFGKWSTEGIDVHDISLTDYIAVKDQYSRFLPHSAGRYQVKRFR KARCPIVERLTCSLMMHGRNNGKKLLTMRIVKHAFEILHILSGDNPLQLLVKAVENSGPR EDSTRIGRAGTVRRQAVDVSSLRRVNQAIWLLCTGAREAAFRNLKTIAECLADEILNASK GSSNSYAIKKKDELERVAKSNR---------------GWVTQIATTPNFPDVLLSSSRDK TLILWKLTRDDNYGTPSKCLKGHSHFVSDVVMSSDGQFALSGSWDNTLRLWDLTEGVTHR QFVEHKKDVLSVAFSPDNRQIVSGSRDHTIKLWNTIGACKYTIEEGHKGWVSSVRFSPSH NVPIIVSCGWDRIVKVWNLKNCKLKTNHIGHSGYLNTIAVSPDGSLCASGGQDGQAMLWD LNESKHLYTLDGGNGINALCFSPNRYWLCAATG--------------------------- -----------------------------------XXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---VPLNPKPFL NNITGKQVEVKLKWGMVYKGFLVSADGYMNMQLANTEEYIDGNLAGALGDVLIRCNNVLY VRDVTDDKEEGQF--MSDVEGDDVAAPVSTGGSMDLESAIAQVVKTAHIHDGLKRGLREC AKALDGREALLCILAENCDEANYVKLVKALCAEHSIKLLKVKDNKKLGEWAGLCKIDKEG TARSVNICSCAVIKNWGEETEALNVV--------XXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----------------EMVNTVRN ALKELE-GSDVAHALKTSDVTDV--MDLSSSKAVIVQIPVPKLKPFRKNQSRIIRELEKK ICGKTFIFLAKRKIIPKPTRKTRNQ-KQKRPRSRTLTAVHDAILEDLVFPAEIVGKRIRV KIDGSKLLKVHLDKSQMTAVQDKIETFTSVYKTLTGKDAVFEFPD-------------GR SRGFG-ARRRRDQTKVEWLPVTKLGRLVKEGKIKTLEDIYLFSLPIKEYQIIDFFLDSKL KDDVLKIMPVQKQTRAGQRTRFKAFVAIGDHDGHVGLGVKCSKEVATAIRGAIILAKLSV IPVRRGYWGNKIGTPHTVPCKVTGRCGSVLVRLIPAPRGTGIVSAPIPKKLMQMAGIDDC YTCASGQTATLGNFAKATFEAIAKTYRYLTPDMWKNNKFLKSPYQEYTDFLAKMSGGNPL LELSADDVSKLISAETHLGSSNLNYQMEQYVYKRKPDGVHMINPRRTWEKLLLAARAIAS IENPADVCVISSRPYGQRAVLKFASATRATAVAGRFTPGTFTNQIQKAFSEPRLLVVSDP QTDSQAIRESSYVNIPVIAFCNTSSPLKHVDIAIPCNNNGIYSIGLMWWMLAREVLRLRG TISRKTPWDVMPDLYFYRAPEDIEKD---------------------------------- -------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXVSASATSVGGTVRQRKGGAVGRQGAGMWRFYTEDSPG IKVGPVPVLVMSVLFIASVFMLHIWGKYTK-QKGEKRKKSFQPMIL-EDTVHLHRFIHGV SFKKRAPQAIKAIKKYTHQRMGTVDVRIDTRLNKEVWSNGIRNVRRRIRVRMERKRNEDE DSSDKFYTLVSYVEVPQVKG--------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------RVGGKGTARRKKXIIHKTATTD DKKVHAQFRKMGLNNIPGIEEVNMFKNDGTVLHFNNPKVQASLQANTFNITGHAEIKPLS ELLPGVLNQFGNSPD--ERKLAQADAAAAEDDDDVPALVGNFDEPSNQE----------- -KTVKARIDNARVHFKNTVETANAIKKMGLRRAMAYLKNVIEKKECVPFRKFKGDVGRNK QAKHFGVTQGRWPEKSARVILELLKNAESNAEQQGLEAENLKFWHVQVNRATQMRRRTYR AHGRINPYMRNPCHIELILVE---------------------------XXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXX-GYLRSSWTKRRKTGGRKNLIRKKRAYELGRPPANTKLGS HRVHEVRTRGGNRKFRALRLDAGNFSWGSESCTRKTRIIDVVYNATNNELVRTKTLVKNA IVMIDATPYKQWFLKYYNVELGKAKKSDSAQDSE----KQSPKALKVFEQRKPMSAIADG LDSQFKQGRLLACIRSRPGQTGVADGYVLEGEELQFYMRKLKTKKGK-------RFQHIR REFSTNIDGRRKVANALTSVKGIGRRFAVVVCKKADIDLNKRMGQITDAEMDKIRTIVIN PQQFKIPVWMLNRIRDRTTGKSSHVYSEQLSRKLMGDLDNLRRIKSNRGIRHQQGLRVRG QHTKTTGRRGRTVGVAKKK-------------------------EEQPSRGKQSRNEKKA RKAICKLGLKQVPGITNITIRKSKNILFVINRPDVYKSSSSDIYVVFGEAKIEDLTQQAS MEAMQHIRDDEEIDETSIEAKDIELVMSQAGVKRSKAVKALRNNSNDIVNAIM---VRTK TVKKAARVCIEKYYTKLTLDFHTNKRVIEEVCHIPSKKLRNKIAGFITHLMARIQKGPVR GISIKLQEEERERRNDYVPEISALEEVDLATLDMLRVLNIQIPEKYQVT------MKWQY KEEHTFDKRRAEGEKIRKKYPDRVPVIVEKAPKARVSDLDKKKYLVPSDLTVGQFYFLIR KRIQLRPEDALFFFVNNVIPPTSATLGQLYQGHHEEDFFLYIAYSDESVYGMRDIRIGKL CLNICTGESGDRLTRAGKVLEQLTGQTPVFSKARITIRTFGIRRNEKISAHVTVRGSKAA EILEKGLKVKEYELPKKCFSNQGNFGFGIQEHIDLGIKYDPGVGIYGMDFYVVLQRAGYN VAYRRRRKNRVGPQHKITEEEARGWFQQTFDGIILGGEXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQVEKAFQRQWQRGANPKKNNLKRYYK NVGLGFKTPKEAIEGTYIDKKCPFTGSVSIRGRILTGIIQKLKMNRTIVIRRDYLHYVRK YNRFEKRHKNMSVHMSPCFRDAKVGDLATVGECRPLCKTVRFNVLKVSRIGKKKKTFEKF LLNIPKMRKTFCKTKTCRKHTPHKITQYKXGKDSLLAQGKRRYDRKQSGYGGQTKPIFHK KAKTTKRIVLKLECNVCKKRKLICIKRCKSLELGGEKRMKGQVIQF--RVTRGQRKGAGS VFKAHTKHRKGAAKLRSVDYAERHGYIKGIVKEILHDPGRGAPLAKIMFRDQYKFRQRTE TFVAAEGMYTGQSIYCGKRADLSIGNVLPVGQMPEGMVVCCLEEKSGDRGRLAKTSGNYA TVVAHNLDTKKTRVRLPSGAKRLIPSANRAMIGIVAGGGRIDKPLLKAGRAYHKYRVKRN CWPRVRGVAMNPVEHPHGGGNHQHIGHASTVRRDTSAGRKVGLIXARRTGRVRGT----- ------KVGVTGKYGTRYGASLRKTVKRMEITQHSKYTCHFCGKDALKRKVVGVWECKKC HKTVAGGAYVVATTSGVTCGSSIRRLRE----GRRPARCYRYCKNKPYPKSRFCRGVPDP KIRIYDLGKKRAGVLDFPCTINIVSDEYEQLSSEALEAARICANKYLVKHVGKEGFHMRV RVHPFHVVRINKMLSCAGADRLQTGMRGAFGKPQGLVARVNIGQAIMSVRVKDGNKAHAI EAFRRAKFKFPGRQKIFESKRWGFTKWPRADFMKMYKEKILIDDGVGVQYKPHKGPLVHW M---KVIRLLGRTGSQGQCTQVTVEFLDEQNRTIIRNVKGPVREGDILCLLESEREARRL RMTKGTSSFGKRHNKTHTFCRRCGRSSFHIQKKTCAGCGFPAKKTRKYNWSEKACRRKTT GTGRLRHIRKVQSQFRTGF-----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----------RHKQTDVMG YILRIRCWQFRQLGSIHRASKSTCPIKARMLGYKNKQGYSIIRVRIRRGGRKRPVAKGAT YGKPVHQGVNQLKNQRSLQAVAEERVGKKYGGLRVLNSYWVAQDGSYKYYEVIMVDPSHV AIRNDPKINWICKASMKHRECRGLTTANKKSRGLGKGLGHTHAKGGSVRANWRRKNTMSL KRRRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXLGFAENFALSGVAAVMSKTAAAPIERVELLVQNQDEMIKMGRLDKPYSGVIDCTR RTFQTEGVIPFWRGNLANCLRYFPTQALNFAFKDTIKSVFKANKNESYAMKFGKNIASGG AAGALSLCFVYSLDYARTRLANDAKSGSKRQFNGLIDVYKKTLKSDGIVGLYRGFVISCV GIIVYRGCYFGFYDTLKPIVIGENANIFMSFALGYCVTISSGLVSYPIDTVRRKMMMT-- ---------------------------------------------------------MTS VSDLDRQIEQLRKCEVVSEAEVKSLCAKAREILVEESNVQSVDAPVTVCGDIHGQFYDLK ELFKVGGNVPETNYLFMGDFVDRGYYSVETFLLLLALKVRYPDRIMLIRGNHESRQITQV YGFYDECLRKYGSVTVWRYCTDVFDYLSLSAVIDDEVFCVHGGLSPSISTLDQIRSIDRK QEVPHDGPMCDLLWSDPEETTGWGTSPRGAGYLFGSDIVQNFNRTNNISLICRAHQLVME GYKWHFQETVLTVWSAPNYCYRCXNVA--------------------------------- XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMQNDAGKYVDM YIPRKCSASGRIIAAKDHASIQMNIAEIN-AEGKMTGSNKTYAICGQIRNMGESDSSIER LAVQDGLIP-VVRGPRKHLKRLRAPKSWMLDKLGGTFAPRPSTGPHKMRECLPMVLLLRN KLKYALNSDESKKIVKQRFIKVDQKVRTDNTFPLGFMDVISIEKTGEHFRILYDVKGRFL VHRIQHEESQYKLCKVKKIKKGPKGIPYLITHDARTIRFINPDIKVNDTIRVXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----KKVKK TSESINARLKLVMKSGKYTLGCSSTLKTLREGKSSLVIMANNTPPLRKSEIEYYSMLAKT GVHHYNGDNKELATACGKYFGVTCLSIIDPGDSDIIKSMP--XXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----CV FSNFKILPGRGRILVTKDGKSVHTINGKCAKYWGKGYKNHKIAWTFASRKDKKKDAASNV RKTKTKRDVGV-RAFIGLSKEELLSRRNQPADVRKAIQEQTIKKAKEKKRALESSKPTVA RKR-KINIAYPATGAQKTIEVDKYEKLKAFDDKRINAEVLADGLGDEFKGYIMCIKGGFD KQGFPMMPGVLTQGRVRLLLAKGSTCYRERRKGERHRRSVQSGIVNHNLSVINVIIIRKG ENDIPGLTDVTIPRRLGPKRASKIRKLFNLDKGDDVRSYVVKRPLPERIKRPKIQRLITP RRLERKRHLIALKKKRAHQAKLDESEYAKMLHQRAHARRERKISLRARTNSKRXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXADKKGPKVTHQV WFEIEIGGEPAGRIDIGLFGKSVPKTVDNFVGLAKHS-GYKGSKFHRVIKDFMIQGGDFT RGDGTGGKSIYFPDENFKLKHYGAGWLSMANAGKDTNGSQFFLTTVKTQWLDGKHVVFGK VLSGMDVVREIEGTQTK-DKPVKDVVIVDCGEKLVEEPFAVDKAPAEEKAKKPTSTYKID ITIPAEDQIVKGTALTTFLKSKVKVDKKLNNLETIVSIKCYVDFSKRYLKYLTKKYLKKS GLRDYMRVVADPKDAYQLRYFNVNQEEDEEE---XXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSAFKLSMNDI EQRILLVLRLYDKVDPEKLSMDTDLQKEFGLDSLDHVEVIMAIEDEFGFEIPDLEAEKMR TPADIKQYIADKEDVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-PKDKIHINIVVI GHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITI DIALWKFATDKFYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKEGQT REHALLAYTLGVKQMIVAVNKMDSTEPAFSEARFGEITKEVSTYLKKIGYNPKAVAFIPI SGFHGDNMLKMPWFKGFAIASGKTLYSALDSIVPPQRPTDKPLRLPLQDV---------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPKQ IMDIKEFLLTARRVGARAVYIKKTRKFKVRCAKYLYTLVVTDEEKAEKLKQSLPPGLTVQ DVK------------------KKRKFTQTIELQIALKNYDPTKDKRFAGTIKLNYTPRPK MSVCIIGNVVHIDQAKQRGLPYRTVDDLKAMGKDKKQVKKLTMKYVAFIASDGIIKTIPR LCCPGFNK---------------------------------------------------- ------------------------------------------------------------ ------EHEIFSLCLKSREIFLSQPILL-LEAPLKICGDIHGQYYDLLRLFEYGGFPPES NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN IK---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---YSFDG ALVFSLLVICTCAYLRRV-PRILLSEKKGFWGVFYKAAVIGSRLHVGVSLSCVLMAIYVL VL-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX >Myzostoma_cirriferum MSERKAVVKNADMPEEMQQDAVDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYIGQVAVLLFKSG----NRSFQTSAVARDIDMAAKYIGAGAATV GVAGSGAGIGTVFGSLVIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLLLFAF- ----------------------------LEKVCTDLISGAKSKKLKLKGPVRMPTKVLRI TTRKTPCGEGS------QMRIHKRVIDLHSSSDVVKSIVSF--------------XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX X----------------------------------------------------------- ------------------------------------------------------------ -GVLRFIMENGAKGCEVVVSGKLRGQRAK------------------------------- ---------------------------------------------------XXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXRKGKEKKVALGPQAADGENIFGVAHIF----------------------- ------------------------------------------------------------ ----------------------------------XXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--- -----------------------------------------------------FGFKSHF GGGRSTGFGLIYDSVEKAEAFEPKHRLRRHGKRRSGKETKNKCKKVRAGEKAKL------ -------------------------LIGEYGLRNKREVWRVKLTLAKIRKAARELLTLEE KDPVRLFNGNALLRRLVRTGVLDEGRMKLDFVLGLKIED--------------------- ------------------------------------------------------------ --MGNTFQKMFHALFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY S--CFTVWDVGGQDKIRPLWRHYFQNTQGLIFVIDSNDRERSQEAKDELHRMLSEDELRE AVLLVFANKQDLPNAMAAAEITEKLGLHELRNRTWYIQATCATSGDGLYEGLDWLSNQLK N--MPLVKDLLNPSTESELRKHKLKRLVQSPNSFFMDVKCPGCYKI-------------- ------------------------------------------------------------ ----------------------HRGGKIVVTLNGRLNKCGVISPRFDVALKDIEKWTSNL LPSRQFG----------------------------------------------------- -----------------------------------------------------------Q IPEDLYHLIKKAVSMRKHLERSRKDKDGKFRLILVESRIHRLGRYYKRTQVLPPNWKYDS ATASALVA---------------------------------------------------- -----------------------------------------SGDNPLQLLVKAVENSGPR EDSTRIGRAGTVRRQAVDVSSLRRVNQAIWLLCTGAREAAFRNLKTIAECLADEILNASK GSSNSYAIKKKDELERVAKSN-MAEQMTLRGTLKGHNGWVTQIATTPNFPDVLLSSSRDK TLILWKLTRDDNYGVPSKCLKGHSHFVSDVVMSSDGQFALSGSWDNTLRLWDLTEGVTHR QFVEHTKDVLSVAFSPDNRQIVSGSRDRTIKLWNTIGACKYTIEDCHTGWVSSVRFSPNH HVPIIVSCGWDRIVKVWNLKNCKLKTNHIGHSGYLNTIAVSPDGSLCASGGQDGQAMLWD LNESKHLYTLDGGNGINALCFSPNRYWLCAATGQTIKIWDLEAKHVVDELQAENVTNPGE KPKCISLAWSTDGQTLFAGYTDKLIRVWQVSVS--MKEYKLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKMIEIDGTKCMLEILDTAGTEQFTAMRDLYMKNGQGFILVYSVT AQSTLTDLNDLYDQIIRVK-LERPPMILVGNKCDLESERSVLNKAKQFNCQFVETSAKLK VNINNVFYQLVRQIEKSSPET-ADKKD-KGDHVNLRVSRQDGHTMHFKIKKHTPLRKLIS AYCQRSGLQIDTMRFMFDGNRILETDTPEQCGMEDDDSIDVFQQQTGGMATVPLNPKPFL NNITGKQVEVKLKWGMVYKGFLVSVDGYMNMQLANTEEYIDGNLAGALGDVLIRCNNVLF VRDV-------------------------AGGSMDLESAIAQVVKTAHIHDGLKRGIREC AKALDRREALLCILAENCDEQNYVKLVKALCAEHSIKLLKVENNKKL------------- ----------------------------------MATIRKKLVIVGDGACGKTCLLIVFS KDQFPEVYVPTVFENYVADIEVEGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSI DSPDSLENIPEKWTPEVGHFCPNVPIILVGNKKDLRNDDNTKRELMKMKQEPVREDEGKL MSDKINAFDYIECSAMTKEGVRDVFETATKAALLVKKKKK--MDDYVQSEENVFVVDEVT NIIKEAIETSIGGSAYQHNKVNQWTSNTVEQCLNNLTKLGKPFKYIVTCVIMQKNGAGLH TASSCFWDNNNDGSCTVRWENKTMYCIVSVFGLTI------------------------- -----------------------------------------------------VRELEKK ICGKSIFFLAKRKIVPKPTRSTRNQ-KQKRPRSRTLTAVHEAIFEDLVFPAEIVGKKNTV K----------------------------------------------------------- ------------------------------------------------------------ ----------------------------------------------------MIILKLSV IPVRRGYWGNKIGTPHTVPVKVTGRCGSVLVRLIPAPRGTGIV----------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------SRPYGQRAVLKFASATRATAVAGRFTPGTFTNQIQKAFSEPRLLVVSDP QTDSQAIRESSYVNIPVIAFCNTSSPLKHVDIAIP---------------LAREVLRLRG TISRTTPWDVMPDLYFYRAPED-------------------------------------- -------------------------------------------KLRTKYKAKTIPIKKGD TVRIMRGSLKSPETRRVQSVYRLKNCIHLEQVTREKANGASVPINIHPSNVMIEELNMQH HRGLILNRKNHISK---------ASPSGTSVGGTLRQRKSGPAGRQGAGMWRFYTEDSPG IKVGPVPVLVMSVLFIASVFMLHIWGKYTK------------------------------ ------------------QRMGTTDVRIDTRLNKEVWSNGIRNVRRRIRVRMERKRNEDE DSSDKFYTLVSYVEVPEVKG--------------------------GNGSFGDIFLGINI QNGEEVAVKVEAHRARHPQLLYESKLYKILQGGLGIPHIRWFGEKNNMVLVMDLLGPSLE DLFNFCSRRFTIKTVLMLGDQMIGRVEYLHNKSFVHRDIKPDNFLMGIGRHCNKVYMIDF GLAKKYRDSRTRIHIPYRDDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRGT LPWQGLKALTKKQKYEKISEKKMSTPVESLTRGYPAEFAMYLNYCRGMRFEEAPDYMYLR QLFRILFRTLNHQYDYVFDWTILKQKAANG----------------------------TD DKKVHAQFRKMGLNTIPGIEEVNMFKNDGTVLHFNNPKVQASLQANTFNITGHAETKALS ELLPGVLNQFGTSGD--ERRLAQGEPAVE-EDDDVPALVGNFDEPSNQE----------- -KSVKARIDNARVHFKNTVETANAIKKMPLRRAMAYLKNVIDKKECVPFRKFKGDVGRNK QAKVFGVTQGRWPQKSARVILELLKNAESNAEQQGLEADNLKFMHIQVNRATQMRRRTYR AHGRINPYMRNPCHIELILVE--------------------------------------- -----------------------------------------KKMIADIDREGSGTIDFND FQTMMTTKMSEKDSKEEILKAFRLFDDDESGKISFKNLKRVAKELGESLTDEELQEADRD GDGEINEAEFLRIMKKTSLY-GITRSSWTKRRKTGGRKNLIRKKRAYELGRPPANTKLGS HRVHEVRTRGGNK----------------------------------------------- --------------------------------------------------RKPMSTISDG LDSQFKQGRLLACIRSRPGQTGVADGYVLEGDELQFYVKKLKTKKGK--LVAGEEFQHIR REFSTNIDGRRKVANALTSVKGI------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------ILFVINRPDVYKSSNSDIYVVFGEAKIEDLTQQAS LEAMQHIRDEEEADESGIE----------AGVKRSKAVKALRNNSNDIVNAIM------- ---------------------------------ITSKKLRNKIAGFVTHLMARIQKGPVR GISIKLQEEERERRNDYVPETSAI------------------------------------ ---------------------------------------------------------LIR KRIHLRPEDALFFFVNNVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYGMRDVRIGKL CINICTGESGDRLTRAGKVLEQLTGQTPV------------------------------- ------------------------------------------------------------ --------------------------------------MGIKFLELIKPFCSVLPEIAKP ERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGIS PIVTSGLIMQLLAGAKIIEVGDSIKDRALFNGAQKLFGMIITIGQSIVYVMTGMYGEPSE IGAGVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVN TGRGSEFEGAIIALFHLMATRQDKIRGLREAFYRQNLPNLMNLLATVFVFGIVIYFQGFR VDLPITSTRYRDQCSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAAKFSGNFLINLLG VWADAGSGGPARSYPIGGLCYYLSPPETLSHVATDPVHAILYIVFMLGSCAFFSKTWIDV SGSSAKDVAKQLKEQQMVIRGHRDKSMVHMLNRYIPTAAAFGGLCIGALSVFADFLGAIG SGTG------------------------------XXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX MVNIPKTRKTFCKTKNCRKHTLHKITQYKKGKDSLLAQGKRRYDRKQKGYGGQTKPIFHK KAKTTKRIV-------------------------------------XXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX X-KRTKKVGVTGKYGTRYGASIRKTVKRMEITQHSKYTCHFCGKDALKRKVVGVWECKKC HKTVAGGAYVVATTSGVTCRSSIRRLRE-------------------------------- ------------------------------------------------------------ ---------INKMLSCAGADRLQTGMRGAFGKPQGLVARVKIGQAIMSVRVKDSNKVHAI EAFRRAKFKFPGRQKIFESKRWGFTKWPRKDFMKMYKEKILIDDG--------------- ----KVIRLLGRTGSQGQCTQVTVEFLDEQNRTIIRNVKGPVREGDILCLLESEREARRL RMTKGTSSFGKRHNKTHTFCRRCGRSSYHIQKKTCAGCGFPAKKTRKYNWSEKACRRKTT GTGRLRHMRKVHAQFKTGF-------------------KELDQWIEQLYDCKQLSERDVT SLCAKAKEILTKESNVQPVKSPVTVCGDVHGQFHDLQELFRIGGKAPDTNYLFMGDYVDR GYYSVETVTLLVVLKVRFAGRLTLLRGNHESRQITQVYGFYDECLRKYGNANVWKSFTDL FDFLPLTALIDEQIFCLHGGLSPSIDTLDHIRSLDRLQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHTNGLTLISRAHQLVMEGFNWCHEKNVVTIFSAPNYCYRC GNQAALMELDDVLKYSFLQFDPAPRRGEPHVTRRTPDYFL-------------------- -----------------------------------------------RGGRKRPVAKGAT YGKPVHQGVNQLKNQRSLQAVAEERVGKKYGGLRVLNSYWVASDGTYKYFEVIMVDPFHV AIRNDPKINWICKPEKKHRECRG-------SRGLGKGLNYAHSRGGSTRANWKRKNTMSL KRRRGIAAARLAEERKAWRRDHPFGFVAKPTKLEDGNINLMMWDCAIPGKKGTIWEPGLY NLKMIFKDDYPSSPPKCKFDPPLFHPNVYPSGTVCLSLLDEEKDWRPAVTIKQILLGIQE LLIEPNVKDPAQAEAYTIYTTNRVDYEARVKVQASKF----------------------- ------------------------DEFRRGKPKKGQTKDEKRALGLVLLRGENLVSMSVE GPPVQQQ--TRHPNIGGGMGAGESRAAGR------------------------------- ----QQEAQVKLVLVGDGGVGKTTFVKRHLTGEFEKKYLATLGVEVHPVFFQTQRGKFTF NVWDTAGQEKFGGLRDGYYIQGQCAIIMFDVTSRVTYKNVPNWHRDLVRVCEGIPIVLAG NKVDIKERKVKAKSITFHRKKNLQYYDISAKSNYNFEKPFLWLARKIVGDLNLEFCAMPA LQPPEMNMDPAVIAQYEKELQEAQNIALPEDEDDI--GVISYYRHKTMELELITNEKKKN KLRLEAERNQLNKKVRMLREELQLLQEQGSYVGEVVKPMDKKKVLVKVHPEGKFVVDIDK NIDMKDVTPNCRVALRNDSYVLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDSQIKEI KEVIELPVKHPELFEALGIAQPKGVLLYGPPGTG----TRAVAHHTECTFIRVSGSELVQ KFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRLESGSGGDSEVQRTMLELLNQLD GFEPKQNIKVIMATNRIDILDSALLRPGRIDRKIEFPAPKEEARADILRIHSRKMNLTRG INLKMIAEQMPGSSGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVSKIMQKDSEKNMSI KKLWK------------------------------------------------------- ---------------------------------------------------------SGG AAGALSLCFVYSLDYARTRLANDAKSGKKRQFNGLVDVYKKTIKSDGVVGLYRGFVISCV GII--------------------------------------------------------- -AVKYSGSMDCAVKVIKAEGFMSLMKGAGANILRGVAGAGVLSGFDAFKDIYIQY--MTS VSDLDRQIEQLRKCEVVSEAEVKSLCAKAREILAEESNVQSVDAPVTVCGDIHGQFYDLK ELFKVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRIMLIRGNHESRQITQV YGFYDECLRKYGSVTVWRYCTDVFDYLSLSAVIDDEVFCVHGGLSPSIATLDQIRSIDRK QEVPHDGPMCDLLWSDPEETTGWGTSPRGAGYLFGSDIVQNFNRTNNISLICRAHQLVME GYKWHFQETVLTVWSAPNYCYRCGNVAAILELDEHLSREFTIFEAAPQESRGKPQADYFL ---------ILYIRNLPYKITTEELYDIFGKYGAIRQMRIGNTAETKGTAFVVYEDIFDA KNACDHLSGFNVCNRYLIVLYYQ---------------------------------SIGV PIKLLHESEGHVITCETISGELFRGKLIEAEDNMNINLQGVDHTARDGKQGHLQ------ -------------------------------------------------MQNDAGKYVDM YIPRKCSASGRIIAAKDHASIQINLAEIN-AEGKMTGTNKTYAICGQLRAMGEADSSLQW LATNDGLIPK---------------------------------GPHKMRECLPMVLLLRN KLKYALNSDESKKIVMQRFIKVDQKVRTDNTFPLGFMDVISIEKTGEHFRILYDVKGRFL VHRIPAEESEYKLCKVKKIKKG------------------------------XXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXX-SSKYDSAITVFSPDGHLFQASYANEAVEKGSLAVGVR RGKCVVLAVEKR------------------------------------------------ ---------------------------------SVLIAGYDNMPQMFQCDPSGNYIPWKA TAIGHNDVSSKKFLERRYKADNE--EDVIHMTLSCLKEASDSAVSETEIELASISKGLKI YSIAEVKDYLQEIE---------------------------------------------- ------------------------------------------------------------ -------------------------------------------LEPGCSVLLNHKVHAVV GVLSDMVDPMVTVMKLEKAPEETYADIGGLDTQITEIKESVELPLTHPELYEEMGIKPPK GVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPS IVFIDEIDAIGTKRYDSNSGGERE-----------LDGFDSRGDVKVVMATNRIETLDPA LIRPGRIDRKIEFPLPDEKTKRRIFRIHTHRMTMAEQVNLEEYISSKDDLSGADIKAICT EAGLLALRERRMKVTNDDFQKAKENVLYRKKDGAPEGLYL-------------------- -------------------------------------------------QADCIIVAGTV TNKMAPALRKVYDQMPEPRWVISMGSCANGGGYYHYSYSVLRGCDRIIPVDIYVPGCPPS AEALLYAILQLQRKIKRMRVLQTWYRR-DFYVRYYVGHKGKFGHEFLEFEFRPDGLMRYA NNSNYKNDVMIRKEVFVHKSVMTELRRIIEDSEIVREDDNMWPAPDRIGRQELEIVMDDN HISFTTSKIGSLLDINQCKDADGIKTFYYLVQDLKCFVFSLIGLHFKIKPIXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------ ------------------EDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGF LCIFAVNLEKSFQDIDQYREQIKRVKDADNIPLVLVGNKVDLP-REVD------------ ----------------------------MGDRYNIFSQLEHLQAKYIGTGHADTSKFEWA VNQHRDTYASYLGHDDMIGLISLAENESKARVRFNIMEKMLQPCGPPPERPAD------- -------------------------------------------WTFASRKDKKKDAASNV RKTKTKRDVGL-RAFIGLSKEELLSKRNQPADVRRAIQEQTIKKAKEKKRALESSKP--- ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------- ---------------------LKVAKVTGANAARIGKLKYVRKAIARVLTVMQANYRKRV LTEVRPKDLRAKQTRAMRRALTSKQLNMKRPKEQRRLKKFGLRKYCVQSSAAGPKVTKQV WFEIEIGGKPAGRIDIGLFGGTVPKTVDNFVGLATGS-GYKGSKFHRVIKDFMIQGGDFT RGDGTGGKSIYFPDENFKLKHYGAGWLSMANAGKDTNGSQFFITTIKTTWLDGKHVVFGK IVSGMDVVRKIESTSTAGDKPKEDVVIVDCGEKHIEEPYVVDKAPSEEKAKKPTSTYKID LTIPAEDMIIKGGQLTTFLKSKVKVEKKLNNLDTIVSIKCFTDFSKRYLKYLTKKYLKKN GLRDYMRVVADPKDAYQLRYFNVNQEEDDEE-----------DEVYGNLVGPDAQYIKLI SSDGHEFIVKKEYAFTSGTIRAMISGPGDFSETETNEITFKEIPSHVLSKVCMYFTYKVR YTNSSSEIPEFPIAPEIALELLMAANFLDCTKIISREEVSNQNKSTSNWFIIHDKVYDVT PFLEEHPGGEEVLIEQAGQDATEVFEDVGHSDDARDMMKPYIIGELPENERSTWSRLMFP AAIAAIAVVSFIMY---------------------------------------------F RAAEKLKNFAVVYVVDITDVPNFNKMYELYDPCTLMFFYRNKHIMIDLGTGNNNKINWAL EDSQEL------------------------------KQLNKELSFLQIHEDYIRDEIKNL RQSYKHAQEEVTRIKSIPLVIGQFLEAVDENTGIVGSTTGSNYYVRILSILDRELLKPSA SVALHKHSNAVVDVLPPEADSSISMLQSDEKPDISYADIGGMDIQKQEVREKIEFPM--- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------PDRRQKRLIFSTITTKMNLSDDVDLEDFVARPD KISGADINAICQEAGMFAVRENRYIVLSKDFEKAYKNTTKKNTQEFGFY----------- ------VLRLYDKIDPEKLTMETDLQKEFGLDSLDHVEVVMAIEDEFGFEIPDLEAEKMK TPADIKQYIADKEDV-------------INFETSEDVRICPTFDELGLKQELTRGIYAYG FEKPSAIQQRAIKPIVKGRDVIAQAQSGTGKTATFSISVLQAIDTQLRETQALVLSPTRE LAVQIQKVILALGDYMSIQVHACIGGTNIGEDLKKLDYGQHVISGTPGRVIDMIKRRSLR TNSIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVCLLSATMPVDVLEMTSKFMTDPI RILVKRDELTLEGIKQFFVAV--------------------------NTKRKVDWLKEKM LEANFTVSSMHGDMPQKERDEIMKVFRSGQTRVLISTDVWSRGLDVQNVSLVINYDLPNN RELYIHRIGRSGRYGRKGVAINFVKSEDIRILRDIEQYYSTQIDEMPMNVADLI------ ------------------------------------------------------------ -----------------------YPLVDDPYMMGKIACANVLSDLYALGITTCDNMLMLL ATSQKMSDLERDTVMPLMIKGFKDQATDAGTGVNGGQTVINPWVTIGGVATTVCQPNEFI MQDNATAGDVLVLTKPLGTQVAVNAYQWTDVPDKWNRIKLVVSQHDVTKAYHRAMFSMAR LNKTASRLMHKYNAHGCTDVTGFGLLGHAQNLAAIQKHDVSFVIHNLPVIAKMAAVSKAC GNLFGLLQGTSPETSGGLLIALPREQAAAFCKDSERQEGYQSWIIGIVEKGNKTARIIDK PRVIEVPAKDRD--------VNSYYIQIDAHAEQCFFDRVTSGTKMSLMFEVAEGGFLDI DVWIVGPDKKTIYNGERESNGKYTFAAHMDGTYHYCFSNKMSTVTPKILMFTMDIGDKPK ESQNKLEEMIGELSQSLFSIKHEQDYMEIRERIHRAINDNTNSRVVLWSFFESLVLITMT LGQIYYLKRFFEVRRIVMADAAKSYMESVKLTLQAAMCLENFPSQRVDQHNKPEVEISSG KELLLKPIKISRNDKESVLIEPSINSVRLSIAIRQTDAIEKVLCHNFIKFMELRAESFGV LRRKAIPGYDVSFLITNFHTEEMYKHKLVEFFMFFMEAIDKEISEMKISINSRGRCYGTE YLSKFSRKKVLLKAIVLGSSGVGKTSLMNKYVTEKFSNQYKATIGADFLTKEVMVGDKLV TMQIWDTAGQERFQSLGVAFYRGADCCVLVYDISDTKSFQALDNWRDEFLIQASPRDPEK F----------------------------------------------------------- --------------------------TAPFDARFPHTNQTRNCYQNFLDYHRCRKVDDFE PCFYFMRVYNSLCPISWVEKWNDQIDNGVFAGKI-------------------------- ------------------------------------------------------------ ----------------------------------------ESVAPTDIEEGMRVGVDRNK YQIHLPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPMLHPERFVNLGI DPPKGVLLYGPPGTGKTLCARAVANRTDACFIR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------QEMGKGSFKYAWVLDKLKAERERGITI DIALWKFETSKFYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAG-------------- REHGLLAYTLGVKQMIVAVNKMDTTDPPFSESRFNEIKKEVQGYLKKI------------ ------------------------------------------------------------ -----------GMIVSFAPAGLSTEVKSVEMHHESLTEALPGDNVGFNVKNV-------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------ELEALRQEADTLKAQIQDARKLASDASLTQMTQGEDAVGRISMRT RRTLRGHLAKIYAMHWGSDSRNLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCSYAP SGSFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDDNIVTSSGDMTCV LWDISTGNTVTVYEGHTGDVMSLSLSPDRNNFVSGACDASAKLWDKREGMCKQTFTGHES DINAIAYFPNGHAFATGSDDATCRLFDIRADQEIGMLSHDNIICGITSVAFSKSGRLLLA GYDDFNCNVWDXLKSERVGVLSGHDNRVSCIGVTEDGMAVATGSWDSFLKIWNMSYSYLF KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMINIGGKQIKLQIWDTAGQES FRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARR DVTKEEGECFAREHGLIFMETSAKTAANVEEAFINTASGIYNKISEGVFDISNEXNGIKI GPQHTASGS-AGSGAQRQSG------ELGDITHHNIKQLKKLNQVIFPVSYNEKFYKDVL DVGELAKLAFFNDIVVGAVCSRIETPSGGRRMYIMTLGCLAPYRGFGVGTLMLNHLLS-- ------------------------------------------------------------ --DIKEFLLTARRIGARAVYIKKSRKFKVRCAKYLYTLVVTDEE---------------- ------------------------------------------KDKRFAGTIKLNHTPRPK MSVCIIGNDVHIDQAKELGLPYRSVEDLKGLNKDKKLVKKLTKKYDAFIASDSIIKTIPR LCGPGFNKAGKFPMPL---DNMASKVDEVKKTIKFQMKKVI------------------- -----------------------------------MANAEKLNVDDIIGRLLEVRGLRPG KNVQLGEQEIRGLCLKSREIFLNQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPDS NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLLSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKEVQNWGENDRGVSFTFGSEVVAKYLLKHDLDLICRAHQVVEDGYEFFAKRQLVT LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPSEKKKFPYGGLGTGRPVTPPRGAKK-- ---MFKNTFQSGFLSILYSIGSKPLQIWEKKVRNGHIKRLTDNDIQSLVLEIVGTNVSTA FITCPADSGKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPF I--------------------FTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDEL PAEFKLYLPVQKK-----IQNLQDPFSTTTEVHIRIQQRNGRKTLTTVQGLNPDYDKKKI LKACKKEFACNATIVDHKEYGEVIQFQGDQRNRFCEFLLKSQLKETVKLHGFXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXSSRFASSLVRQLPRNLTKKNVNQIAAVGVRQFSMSGEITSILEERIMGSPKANLEET GRVLSIGDGIARVYGMNNVQAEEMVEFQDGVKGMALNLETDNVGIVVFGNDKLIKEGDIV KRTGAIVDVPVGAEILGRVVDALGNPIDGKGPLGCKDRRRVGLKAPGIIPRASVREPMQT GLKAVDSLVPIGRGQRELIIGDRQTGKTAVAIDTIINQKQFNDGADESKKLYCIYVAIGQ KRSTVAQILKRLTDADAMKYTIIVSATASDAAPLQYLAPYSGCAMGEFFRDSGKHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSEAFGGGSLTALPVIE TQAGDVSAYIPTNVISITDGQIFLESELFYKGVRPAINVGLSVSRVGSAAQLKAMKQVAG SMKLDLAQYREVAAFAQFGSDLDAATQQLLSRGVRLTELLKQGQYVPMRVEEQVCVIFSG VKAHLDKIDPSQITDFESKFVDHIRTAQQDLLKAIRDAGALSPELEEKLKKVVIDFVS-- XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXMPKVRRTKKPPPEGLELIEPTLEELDQKMREAEADP HEGKRKIEALWPIFRLHHQKSRYVYDLFYRRKAISRELYDYCLKEKIADGNLIAKWKKQG YENLCCLRCIQTRDTNFGTSCICRVPKTKLEEGKIVECVHCGCRGCSGEYAQVIKMLGNG RLEAQCIDGVRRLCHIRGKLRKKVWINQGDVILLGLRDYQDSKADVILKYSADESRNLKL YGELPDNTKINENDNEGVAFEDIDDILVRFLMKLSHETVTIELKNGTVVQGTIAGVDTAM NTHLKNVKMTLKNADSIQLNSLSIRGNNIRYYMLPDALPLDTLLVDDTPRAKQRR----K PRTEMSFEELQQREQEEFAKGPLSILTESVRNNTQVLINCRNNRKLLGRVKAFDRHCNMV MENVQELWVEKPKN---KSKGRPVNKDRYITKLFLRGDSVILVLKNP--MVIDGRGHLLG RLSAIVAKSLLNGDRIAVVRCEGIMRSGSFYRNKLKFRDYLRKRMNTNPSR--------- ------------------------------------------------------------ -----------------------------------------------------------A GDAEKGKKVFVQRCAQCHTVEKGGKHKTGPNLNGLFGRKTGQAAGFSYTAANQNKGITWG KDTLWEYLENPKKYIPGTKMVFAGLKKKAERADLIAYLEKST-IFVERTLAIIKPDSISP EIEEIILQNGFDIINKRRVHLTPEQASEFYAEHYGKMFFPSLVAFMSSGPIVALDISRSR AVSIWRQLIGPTNTFRAREVHPESIRAIYGTDDLRNAVHGSDTFINAAREIRFFFPGSLV EPVVTGQSARDYMGRLVNPTLLQGLTQLSKAKPADCVTWLADWLMENNPNKPK------- -----------------------------------------LVSVTLGSDGFDTYRCDRN LCMGIKLAHMATIMRCANNDDAITIRSEDSADVMTFHFEDKSGEKESKYELKLMDIDQDH LGIPDTEYVCAVKMPSAQMQKICRDLSMIGDTVSVSCTKDGLTFQAGGDMGKGSITIRQT SSADKEDEAVCIEMTEAVTLSFALRYLNSFAKATPLCPQVSLSMSPDVPLVVEYKIEDEG HIRFYLAPKVEDD---KALGSTTAGKRSSAGHVVAVIGAVVDVQFDGELPPILNALEVEG RTPRLVLEVAQHLGENTVRTIAMDGTEGLVRGITCKDTGSPITIPVGPETLGRIINVIGE PIDERGPVNSEHMAPIHADAPEFVDMSVEQEILETGIKVVDLLAPYAKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIEGGVISLKDKSSKVALVYG QMNEPPGARARVCLTGLTVAEYFRDQGGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGSMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDAMTVLSRGIA ELGIYPAVDPLDSSSRILDPNVVGKEHYDCARSVQKVLQNFRSLQDIIAILGMDELSEED KLTVARARKMQRFLSQPFQVAEVFTGSPGKYVPLKETIVGFQKILGGEMDDIPEQAFYMV GNIDEVIQKAESLAK--MLMPKKNSRLIFEELFKDGVVVAKKNFSC-KHPVIPVPNLHVI KTM--------------------------------------------------------- -----------------MGKQNSKLRPEALQDLQSCTKFTEEEIQEWYKGFLKDCPSGTL SVEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFLCALSVTSRGRLDEKLKW AFSMYDLDANGFISRQEMLEIVQAIYKMVGTVMKMPEDESTPEKRTDKIFRQMDTNDDGK LSLEEFIEGAKSDPSIVRLLQCDP------------------------------------ ---------------------------DNPNQSDLIEQAAEMLYGLIHARYIMTNRGIAQ MVEKWQAGDFGTCPRVYCENAYLLPIGLSDLPGESMVKLYCPKCQDVYTPKSSRNHHTDG SYFGTGFPHMLFMVHPEYRPQRPPNQFSPRLYGFKIHHLAYALQYQASSNFKMGYGGSSK MTNTNGVRRGTRYMFSRPFRKSGTIPLKVYMQIY-------------------------- ------------------------------------------------------------ -------------------------------------SSRFAYKQMSPEDPSMEWKDLAD RGARSIFWVELMRGLGMGLAAMFKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAICPAQAITIEAEERADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEY ATETHEELLYNKEKLLENGDKWEPEIAANLVADHLYRMSGPAKVAKIE--QNSAGDKDQQ EAIEQIDDVQNNIDSLNEQASEEILKVEQKFNKLRQPFFQKRSDLITKIPNFWVTAFVNH PQVSALLNEKDEEALQHLSKLEVQEFEDIKSGYKIIFTFSTNDYFENDVIS--------- ------------------------------------------------------------ ------------------KLTKEEEMLLQDFSRSVSTKSSVLFFGNALVVSALPIWLFWR IHQMDLQIIFAVATIVSMFIITWSYKNVQFLLKHKIALKCGDAITREVMRSIPENKKMSR KEKDERVMWRKNEVSDYEATTFSIFYNNILFITMVLFLSFFVLYSFTPLFNYVGTILGSG AILALFSTGTK--QGKICQFKLVLLGESAVGKSSLVLRFVKAQFHEYQESTIGAAFLTQT VCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNADTYQRAKTWVQELQRQ ASPNIVIALTGNKADLRMVDTDEAQTYATENHLLFMETSAKTSMNVNDLFLKIAKELPKT DPNVNLTEDTMAEYLASIFGTEKDKVNCSFYFKIGACRHGERCSRLHNKPTFSQTMVMSN LYLNPQNNAQ-QFTEVEVQEHFDDFFEEIFVEMQEKYGEIEEMNVCDNLGDHLVGNVYVK FHKEEDAEKAVQGTGNRWFNGRPVNSELTPVTDFREACCRQYEMGECTRGGFCNFMHLKP ISRELRKKLYGKSKRRRSRSQSKSRDRSRR-RDRKRRSRSRDKR---------------- ----------------------------------------------SSSNKVFEIDAHIG CAMSGLIPDGRTLVDHTRSVSQDHTFTYDEPISIKTVCQRISNKALSYSDPDAD-TRMSR PFGVSMLVGG-------------------------------------------------- ----------------------------------------------AQKTWEISNDINNV SSIDEIYRYDAQKQKDITSAKPWAKDPHYFKHISISALALLKMVMHARSGGNIEIMGLLL GKLDGETMIVMDCFAAPVEGTETRVNAQEQAYEYMAQYTIQAKEVKRLENVIGWYHSHPG YGCWLSGIDVSTQALNQLFQEPFVAVVIDPIRTISAGKVNIGAFRTYPKEYKPADEGPSE YQVIPLNKIEDFGVHCKQYYPLEVSYFKSSLDVRLLNLLWNKYWVNTLSTSTLLTNAEYM TGQIHDLADKLEQADNHLSRSTFADRKIEDKLSKAAKDGCKTTIEAIHGLMSQVIKNKLF N----------------------------------------------------------- --------------------------RICLDILKDKWSPALQIRTVLLSIQALLSSPNPD DPLANDVAEKWKSNEKEAIEIAQQWTKLYAEEANDLLDYEEEETPSAKGVKGSYVSIHSS GFRDFLLKPELLRSIVDCGFEHPSEVQSECIPQAILSMDVLCQAKSGMGKTAVFVLATLQ QLDPVDGQVSVLVLCHTRELAFQISKEYQRFSKYTEGFRVAVFFGGTPISEDLTVLREKC PHVVVGTPGRILALIKNLVLKDLKHFILDECDKMLEQLDMRRDVQEIFKNTPHEKQVMMF SATLSKEIRPVCKKFMQDPLEVYVDDEKKLTLHGLQQHYVKLKENEKNRKLFDLLDALEF NQVIIFVRSVSRCVALNNLLVEQNFPSVDIHSALVQEERLKRYSMFKNFEKRILVATNLF GRGMDIERVNIVFNYDMPSDTDTYLHKVARAGRFGTKGLAITFVSEESDAKVPPTYGDLG KSGRDIFGKGFNYGFFKLECKTKTKSGVEFTTNGSSILDSGRATGSLETKYKCPTYGLTL TEKWNTDNVLANEIVVEDQLLKGSKLTFDTQFAPQTGKMNAKVKAAYKRPYLNLGCDIDF DYAGPVVHGALVTEYKGWLAGLQGSFDKSKLTKNNIALGYSGGDFTLHSALGAGEEFSGS YHQKINPNLEAAVSLSWNNSNNSSKMAIGSKYVIDKDSNVRVKLNNAGQLGFAYEQRINS GVKLILSTLCEAKNINQGGHKVGIGLDLEA---RERALEAYRNVLIKHNEGTAALKKWRE ALKEMTRDYNKSEDDLKALQSVGQIVGEVLKQLTPEKFIVKASNGPRYVVGCRGTLDRSK LKQGTRVALDMTTLTIMKALPREVDPMVYNMSCEDPGKINYSDVGGLAEQIRELREVIEL PLNNPELFLRVGIT----CLLYGPPGTGKTLLARAVAAQLDVNFLKVVSSAIVDKYIGES ARLIREMFAYARDHQPCIIFMDEIDAI--------------------------------- ------------------------------------------------------------ ----------------------------------------------------------EN LSSVISKFSDEYTNTTPKKLKVIDAYLFCIVLVGVIQFLYCCIVGTFPFNSFLSGFISCV ASFVFGVCLRVQVNPENKMDF-SIASERAFADFIFAHAILHLVVINFIG-------LLPL ELIDKCIGSHIHVILKKDREIWGTLLGFDAYVNMVLEDVTELEVTPEGKRITKLDQILLN GNNIAMLVPGGEKP---------------------------------------------- ----------------------------------------DIAKELRLPPIKLHCSMLAE DAIKAALNDYKTK--MLVLVAGDFHLPYRASSISAQFKKLLVPGKIDHILCTGNLVCKST YDYLKTLASDVHVVKGDFDENSSWPDQKVITVGQFRIGLCHGHQIIPWGDVEALSMVQRQ LDVDVMVTGHTHKHETFEHESCLYINPGSITGAYSPLCEEVIPSFVLLDMQTSAIVSYVY RLIDDAVKVERIEFKKMPKVYKPGRISVVLTGRHAGCKTVVLKVHSSGTDSKKFSHAIVA GLEKHPLKVTKRMSNKKIAKKTHLKVFVKTINLNHLLPTRYIFDKME--ALESDTLSVVD KKKKYQKALKTALIQTYQSGAHSWFFKKLRF----------------------------- -------------------------------------GPVVPMVFEGDACRTGRMILGET NPLESRPGTIRGDYGIDLGRNICHGSDGVDSAKKEIAHWFKDSELTGWSRLIDPAIYEXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPAKQLMRMATEKNQKNAGLRGTVPKTLRQ KDDKYPVEPWLIGLFIFVVCGSAVFQIIQSIRMINIKNWTGVATWQWVANDENCGICRMP FDGCCTDCKFPGDDCPLVWGECSHCFHIHCILKWLQTSQSQQRCAMCRQQWKFNKMIRFI LIQNRAGKTRLAKWYVEFDDDEKQKLIEEVHALVTIRDAKHTNFVEFRNYKIVYRRYAGL YFCICVDITDNNLAYLEAIHNFVEVLNEYFQNVCELDLVFNFYKVYTVVDEMFLAGEIRE TSQTKVLKQLLTIQSLE------------------------------------------- -------ADASLLGHLMVVAKNVAAEESGYRLVVNNGKDGAQSVYHLHLHVMGGRQMSWP PMGGLISYFKGLIGSKERRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVTYQN LKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSMDKERMGISKQELAQMLEEDELRGAR LVVFANKQDIEGAMTVTEVSNSLGLSGLKDRKWQIFRTSAIKGDGLNEAMDWLSTELQS- --LYFHIGETERKCFIEELPDETMVVGRYKVEIGDPRTGQFRPTGEGFGMHVEVTDPEEE VVLSRAYAGEGRFTFTSHSSGEHFICLYSNSTAWFGGAQ--------------------- ---------------------------------------------------------VVT GFWQMRHLKGFFEAKKLVMFYHISLEHEILLHPRNFGPSLLSIVKQKLFSEVEGTCTGKY GFVIAVTMIDNIGAGTVLPGQGFALYPIKYKAIVFKPFKGEVVDGVVTQINKVGMFADIG PLSCFISKHAIPVDMEFGSESSGPCFKSKDEDTVIAEGDSIRIKIVGTRVDATDIFAIGS LLDHYLGCIS-------FTGYKRGQRNQYEHTALLHLEGVHSRDDAKFYVGKKCYYLYFA NKKVAEDGTKRRSGIRSIKGNVMRPHGNSGVVRAKFNSNLPPNAIGAQIRIM--MAKKTY DHLFKLLLIGDSGVGKTSLLFRFSDNAFNQTFISTIGIDFKIQTLEIDGKKIKLQIWDTA GQERFHTITTSYYRGAMGILLVYDITSQQSFDNMQKWLQNIMNHA--------------- -----------------------------------------------MPQNEHIELHRKR HGYRLDYHEKKRKKESRQPKIDALKAKKLRGIKAKLYNKKRHSEKIQMKKTIKMHEEKKT KQK-EEKISEGALPAYLLDREKQSSAKVLSNMIKQKRKEKAGKWDVPIPKVKAVSEKETF KVVKTGKSRRKAWKRMVTKVTYVGEEFTRKHPKYERFIRPMALRFKKAHVTHPELKATFC LPIIGVKKNPSSVLNTSLGVITKGTVIEVNISELGLVTQSGKVVWGKFAQVTNHPENDGC INAVLLV----------------------------------------------------- ---SGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAYGNMCRGGRMF------------ -------------------------RGHRVEKIPELPLVVEDEAIMHTTTQSAMKFLNDA GAKSELEKVKDYHNLRAGKGKMRGRRFRSKVGPLIIH----------------------- --LLKLAPGGHVGRFCIFTRSAMEAL--IFGT--STETGKHNFKFPHPIM-NKGLKECFR ELLEKGVLRDPKV-AKKTATRANPLRNKARMLELNPFILEQRK----------------- -----------------GNNEQELASKTLYIQNKKFYLDVKQNRRGRFIKIAEVAMHGKK SRLLLPMSTAAEFRTKLGDFTSRYAELGPPNPNNIPEDGRVMSEVIFKENRRYYMDLKEN QRGRFLKVSLYMGVRPTVFIPAQGMIEMRDALTDLLEEFGTDDHDGAEQLPESQQMRSEN KMFYFDSGQNNRGVYVRVSESNYRTSITIPERSLVRFTETLT-----------EVQMRAK IHQKLTETGERDRLRDLLRTRLVECGWRDQLKKHCKEVVARKG----------------- -------------------------MNIRRCTPSDLMNMQNCNLLCLPENYQMKYYFYHG LSWPQLSFVAEDECGKIVGYVLAKMEEEPSDSVPHGHITSVAVRRSYRHLGIARKLMDQA SRAMVENFDAKYVSLHVRISNRAALHLYVTALGFEIYETEPKYYADGEDAYAMKKDLT-- ----MTHTILLVQPRPKAESRTYSDYESLNECLEGVCKIYEEYLKQVNPQMASITYDISQ LFEFIDNLTDLSCLVFKSPNNSYVPHNKAWLKEKIYQLLRHQAGQ--EENKEKPQETKAR EVPAYPLLKNSDMGEEMRNETMDIGATMCEKYSSNNETAAKFIKESMDKKFGSSWHVIVG EGFGFEVTHEVKNLFHMYFGGTLSILIWKCSXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXMQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLG LWDTAXQEDYDRLRPLSYPQTDVFLICFSLISPSSFENVKAKWAQEVNHHCPNTPCILVG TKVDLREDKEAIAKLKAKNHAPIEYPEGLVMAKDIKAVKYLECSALTQKGLKTVFDEAIR AVLCPKPKPKKRPVCTLL------------------------------------------ ----------------------YTADKEFTYEELLERVFEEMREKNPDMVAGERKQFKLK PPQVMKVGSRKTSFLNFHPICTMMRRDEAHVRSFI------------------------- ------------------------------------------------------------ --------YDDAVEERVVNEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTKPDGK DYSVHRLILGTHTSDEQNHLLIASVQLPNDNAQFDASQYDSERGEFGGFGSVSGKIEIEI KINHEGEVNRARYMPHNPCVIATKTPSSEVLVFDYTKHPSKPDPNGQCKPELRLRGHKKE GYGLSWNPNVNGYLLSASDDHTICLWDINQNPVQENIIEALGIFNGHTSVVEDVAWHLLH ESLFGSVADDQKLMIWDTRSNNHSKPSHIVDAHTAEVNCLSFNPYSEFILATGSADKTVA LWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQSAEDA EDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEEADTAPG DLE-PAQSRARVYGDVNSYKPRDYWDYENHIVEWSLQDDYQVVRKLGRGKYSEVFEAINV LNNEKCVIKILKPVKKKKIKREIKILQNLKNGVNVINLLAIVKDPVSRTPALVFEHVNNT DFKQLYQTLLDYDIRYYIFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLA EFYHSGQEYNVRVASRYFKGPELLLDYQMYDYSLDLWSLGCMFASMIFRKEPFFHGHDNY DQLVRITKVLGTEDLHEYLDHYKIVLDPKFNDILGRHSRKRWERFVHAENQHLVSSEALD FLDKLLRYDHATRLTAREAMDHPYF----------------------------------- ------------------------------------------------------------ ----------------------------------------------------PISENSII NDALGKCDIICIEDIIHELYTCGPNFKQANNFMWPFKLRNPRGGWNKRRNHFVEGGDYGN REFLINKLVQKM------------------------------------------------ ------------------CCGIEAEDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEK AYFILDELILAGEVQETSKKTVLKAITAQDVLQED------------MSKAHPPELKKFI DKKVQLTLNGSRRVGGVLRGFDPFMNLTLEEAVEFKKNGEQQQIGFVVIRGNGIMMLEAL ERVDFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTV RL-------------------------------------------------ERGSDVIIM LAGNKTDLTDKRQVSVDEGEKKAKELNVLFVETSAKSGYNVKQLFRRVAAALPGME---- -----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMVDSG TRKALASIPLLKTKSGPRDKDLWPQRLKEEYVSLIEYVKNNKESDNDWFRLESNKEGTRW FGKCWYIHELLRYEFDIEFDIPITYPATAPEIAIPELEGKTAKMYRGGRICLTDHFKPLW AKNINKFGIGHAMALGLGPWLAVEVP------------LLGNTSMFDDVKRMNKRQLYYQ ALNFAIIISSAFMIWKGLMVVTGSESPIVVVLSGSMEPAFYRGDLLLLTNKEEQPIRAGD IIVFKIEGRDIPIVHRVIKVHEKETGDVKFLTKGDNNQVDDRGLYAPGQLWLKRQDVVGR AEGFLPYVGMVTIIMNDYPKFKYAVLILLGFFVLIHREITEMNPEYDYLFKLLLIGDSGV GKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYR GAHGIIVVYDCTDNETFGNVKQWLQEIDRYASQEVNKLLVGNKSDLTTKKVVSHEAAKEY ADQLEIPFLETSAKNATNVEQAFMTMAAEIKNRMGPGSAGSNVTITNSTPVQPKGGSMC- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------DAIGTKRFDSEKAGDREVQRTMLELLNQLDGFESQQE IKVIAATNRVDILDPALLRSGRLDRKIEFPAPNEEARARIL------------------- ----------------EAGMIALRRNATELMHEDFMDAILEVQAKKKASLNYYAKDAADQ NFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRQDKRVKLQIWD TAGQERYRTITTAYYRGAMGFILMYDVTNEESFGAVQDWCTQIKTYSWDNAQVVLVGNKC DMEDERVVSTERGRELADQLGLEFFETSAKENVNVKAVFERLVDIICDKMSESLDADPSQ TKRLTENPNPQNSGCNC---HKAAVQRNYIVQPRLTYKTVEAVNGPLVILENVKFPIFAE IVNLRLSDGTQRRGQVLEVSGSKAVVQVFEGTTGIDTRHTTCEFTGDILKATVSEDMLGR AFNGSGKPIDNGPPVLAEDFFDIQGKPINPSCRTYPQQMIQTGISAIDGMNSIARGQKIP IFSAAGLPHNEIAAQICRQAGLVKNSGKDVQDNDDDNFAIVFAAMGVNKETARFFKQDFE QNGSLANVCLFLNLANDPTIERIITPRIALTTAEYFAYELGKHVLVILTDMSSYADALRE VSVAREEVPGRRGYPGYMYTDLATIYERAGRVEGKSGSITQIPILTMPNDDITHPIPDLT GYITEGQIYVDRQLYQRQIYPPINVLPSLSRLMKSAIGKDMTREDHSDVSNQLYANYAIG KDVQAMKAVVGEEALSSEDLLYLEFLTKFEKTFIAQEMNENRTVFETLDIGWQLLRKFPR ELLRRIPKPMLDKYYDRQ----GFIGIKFCQECNNMLYAKEDKERRQLMYSCRNCDYSEV ATTRCIYVNKIEHDVDELTSIVPDVRVDPTLPRTKEHPCNKCGHKESVFFQSQTNRTDGG MRLYYVCTAPNCGHRWCEKVPYKVRNIDDAVTGRKLIELAENEMPGLMKMRELYGPQKIL KGCRIAGCLHMTVQTAVLIETLKELGADVTWSSCNIFSTVDEAAAAIAATGTPVYAWKGE TDEEYIWCIEQTLIFPDGQPLNMILDDGGD------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------FDCELDVAWLNTNA-KKTTVQPQVDRYTLKNGRHLIILAEGRL VNLGCAHGHPSFVMSNSFTNQVLAQIELWTNPEKYPI----------------HLDKIGV KLTKLTEDQAEYLGIPVDGPFKVDHYRY-AEEKQEPVAAIEEPLDLVRLGLDERVLVKMR HDRELSGILHGYDQHLNMVLGDVKEKVTIREYDEETFEEVIYTKEREIALLFVRGDGVIL VSPPLRS--SSNVENVPPQVVKRVCKEVQELVANPPEGIKVTINERNLSEIYATIEGPAE TAYTGGTFKMKLVLGKNFPTEPPQGYFITKIFHPNVSSNGEICVNTLKKDWKADHGIHHI LLVVKCLLIHPNPESALNEEAGKLLLEDYQAFLARAQLMTDIHAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ---YQWRTGLYLAASASAEFFADIALCPMEAAKVRIQTQPGFATTLREAWPKIANSEGAW GFYKGLTPLWGRQIPY-------------------------------------------- ----------------LNQKKGATVGSVYQELGMAGLWGGLFPRIIMIGTLTALQWFIYD SVKVFFKLPRPPPPEMPESLKRK--HWKLERYLSAAVVPLIPAAIVYLLEALVASLVLHT HWGFECILTDYIHLSIMALACLFFVNYHGDGVARCTRNVFLHLTEEFEEDAATLSFPKEF ENADTLLISEVKRKNQSEAAEDEVEYNEVFTKTVKYAGNFSKFSTKEVIHSIRNILQKKQ LHRFELAALANLCPESAEEAKAYIPSLGQRFSDNDIQSILDDMKDYISLQ-ANQPHLSKQ SLDELDVSQLTPLTHDVISRQATINIGTIGHVAHGKSTLVKAISGVQTVRFKNELERNIT IKLGYANAKIYFCDDESVPPVHRYTSRGSSYPDSFPCEFAKNAHYKLVRHV--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------PDIYTDLTVQYYLLK RLLGVKTEGNKKGVKVQPLAKTEMIMVNIGSLSSGGKVQNVKNLMAKISLSNPVCTSVGE ----------------------------MAELLLDPQIRFWVFLPIVIITFLTGIIRHYV TILMASEKKVEMQQIEDSQALIRSCRLRENGKYISKQGFLMRREFFNNDENGFLAKNPMT DPSMMTEMMKGNMSNVLPMIVIGGWITWAFSGFLTTKVPFPLTLRFKPMLQRGVELASLD AA-VSSMSWYFLNVFGLRSMYNLILGSDNAADQSKMMQDQMSGAAVAMPPNADKAFRAEW EALDVVDHRWVLDGIEEELMMFLFDWFSDLLNYLGLWKKSGKIVFLGLDNAGKTTLLSVL K-GHLTQAVPTHHPTSEELTMGGVRFTTYDLGGHQQARRVWKDYFPAVDAIVFLVDAADR QRLPEAQAELGSLLKDEQVSSAPILILGNKIDIPGACGEDELRQWFSLYDKATGKGTVAR NDLRPLELFMCCVKKKQGYGEGFRWLAQYI-VFRRNRPGTKAQDWCNWPLESFDEMDTTL AVQQFIQQTIRQDFCEVDTILDSPDGQDIGVWKYEHLRQFCKELNGLAVRLQGECHAETC NKMTAT------------------------------------------------------ --------------------------------RFTTYVIKYDLMSKDNLIVPIMD----- IKLMSSDQEIFECEKDVVQQSVTIRTMLEDDETDDDAIPLPNIN---------------- ------------------------------------------------------------ ------------------------------------NKRTVK-GKKGGKKKPVDPFTKKD WYDIKVPAFFNTRNIGKTPVNRTAGTKIASDGLKGRVFEVNLADLQTEEDAHRKYRLICE EVDGTSVLTNF------------------------------------------------- ------------------------KEVVSGSIKEFVAKCIPDAFAKEIQNRCKYIYPLQD VHVRKVKMLKKPKFDM-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------NTGRGKNKSVELEDVKFHQCVRLSRFEN DRTISFIPPDGEFELMNYRLNTHVKPLIWVESVIERYEHSRIEIMIKAKSQFKRRSTANN VEIEVPIPADADSPKFKTTIGSCRYVPERNAVIWTVKSFPGGKEFLMRAHFKLPSVAADM SEGHPPINVRFEIPYFTVSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQIRTKMGILEK IAEIEREVARTQKNKATEYHLGLLKAKLARYRAQLLEPTGKSGGKGEGFDVMKSGDARVA LIGFPSVGKSTLLSTLTKTQSECAGYEFTTLTCIPGIIEHNGACIQLLDLPGIIEGAAHG KGRGRQVIAVARTADMVIMMLDATKSDIQRELLHKELETVGLRLNQRKPNIYYKPKNAGG VSFNSMVPLTHVDSKLVSMILAEYKIHNAEVLFREDCTADELIDVIVGNRIYMPCLYVYN KIDQISVEEVDRIARSPHSVVVSCNFKLNLEYLIDVVWDYLALVRVFTKKRGERPDFEGG IILRSG-CTVEHVCHGVHRTLVPLFKYALVWGASTKYNPQRVGLAHKMAHDDVIQIVKKM AKHHPDLIFCRKQPGVAIGRLCEKCDGKCVICDSYVRPSTLVRICDECNYGSYQGRCVTC GGPGVADAYYCKECTFQEKDRDGCPKIVNLGSAKTDLFYERKKYGFKKRPNLPPISSEKI QNKDGLRKIRVPAHRLSPLKESWMKIFTPIVENLHLQIRFNVKAKCVELKACDTTTEINA LQKAVDFIQAFMLGFDVDDALALVRLDELYLETFQVTDVKRLKGDHLARAIGRIAG---- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------CSNVPRL VPGWTKPICIGRHAFGDQYRATDLVIKGNPKAELVFTDTAGKETRHPVYDFKGGDGVCMA MYNTDESIRGFAHSCMQYALKKSWPLY-------------------------------KA ANIWYEHRLIDDMVAQALKS---------------------------------------- ------------------------------------------------------------ ---------------------------------------------MGGLLSKIFGNREMR ILMLGLDAAGKTTVLYKLKLGNSVTTIPTVGFNVETVTYKNIKFNVWDVGGQDKIRPLWR HYYTGTQGLIFVVDCADRDRIDEAKQELQKIINDREMKDAVILIFANKQDIPDAMKPQEI QERLALTRMRDRNWFVQPACATTGDGLYEGLAWLTSNTK------TSVDVSKLNDFLSQR SYIDGYVPSQSDVAVFSAVGN-DAKFIHASRWKKHISSYSSDFASLPGVKPDLAKLSFCG GVAEEDDDDFDVFGDAAEALKKKREEEYWAKKAPKVIAKSSVLFDVKCWDDETDMAELER CVRTVQMDGLLWGASKLVEVGYGIKKLQINAVVEDEKVSTDDLEEQICGFEDYVQSVDIA AFNKI------------------------------------------------------- ---KIAGRAVLIGGQPGTGKTALAMGMAQALGQDTPFTAMASSEIFSMEMNKTEALTQAF RKSIGVRIKEETEIIEGEVV--------------------------TIYDLGAKMIESLT KEKVHAGDIVTIDKASGKISKLGRSFTRARDYDAMGAQTKFVQCPQGELQKRKEVVH--- ------------------------------------------------------------ ------------------------------------------------------------ --EIKQILEIRAEEEDVEMSDEAMTLLMRVGSETSLRYSIQLISLANMVARRRKATEVGI QDIKKIYSLFTDVARSTAFLDEY----------KYDLTLKIAKYLDRHLIFPLLEYQNTK DMFDQNDMMKVKLDLLNDTMMIDFIIDIYTGLYGCDSEAKHYIERRTEVVEQLEQFKADI APCHKIFQNEEIKADNIRDGVPFLEFLIERFDFKREYVDLLYRYSKFTYECGFYQDASVN LMYYISIVQAPDKNYVNALWGKLASEILTQEWDAALEDQKRLRDYIDNALSSLQQRTWLI HWSLFIYFN------------LGQPQYLNAIQTTCPHILRYVATAVITNRGVLKDLIRVI EQESYTYEDPITDLIKCIYIDFDFGKAQKKLIECQKVLADDFFLIAWHDDFMEHARLVIF ETFVRVHQCISINMLAENLNMTSESAEKWIVDLIRNAKLD-------------------- ------------------------------------------------------------ ----KFDSSRDRSKPFVFTIGKGAVIRGWDEGVMQMSVGENSILTCSPDYAYGERGHPGV IPPNAELIFDVELIGV-MPKYFCDYCDTYLTHDSPSVRKTHCGGRKHKENVRMYYQKWLE DEVQKLVDDTTASYTGGKFP------PKAAIPPPGAMG-GPPGPPGPMMGPPGAGPMPPM RPPMG-VRPGFPPMGGP--LTLKKDINRACELLESLQQHSDLPNLAALQKVLQSEFLHSV REVYEHVYQTVDIAGSPEVRANATAKATVAAFAAGEGHSHPRIVELPKPEEGLGFNVMGG KEQASPIYISRII---------------QLLSVNGVSVEGQHHEMAVELLKQAQGSVKLV VRYTPTVLDEMETRFDKQRTSRR--ILVLVGVVICEPSVFFEEKFWTERWLDSEHK-SDI GKFKLAHGKFYSDQEDDLGLQTSQDARFYATSAKFDS-FSNKDKTLVVQFSVKHDQDIDC GGGYVKLFPSSVDQKAMHGESPYNIMFGPDICGPGTKKVHVIFNYKGKNLLIKKDIRCKD DVMTHI------------------------------------------------------ -----------------------KPEDWDEEMDGEWEPPMVDNPDYKGEWTPKQIKNPNY QGTWVHPKIANPEYVADEFLYAFDDFSLIGLDLWQVKSGTIFDNFLITDCPDHASEVAQA IVD-SRDGEKKMKEESEEAERKRDEEERKKAEEEGGDDDEEFDE------EATLKVVKAI VILNADGKRVISRYYDDTYPTVKEQKSVFKKTGKANSEIAMLEKWTAIYRNHIDLYFYVF GSKQENEILLSTVLDTMYEAVSIVLRKDVTEDAMLRNFDSVLLIVDELCDNGIFLESDAS LLASRVNHKADDVPLSEQTVAQVLQSAKDQLKWTLLKMNVFRLIGDLSHLFAILVLILKI WKTRSCSGLSLKTQVLFALVFCTRYLDLFINFVSLYNSLMKIVFIASALATCYLMYFKFK ATCNTNQDSFRIEFLIVPVAGLAFLVNHDFTPLEILWTFSIYLESLAILPQLFLISKTGE AETITSHYLFALGLYRALYILNWIYRYYYEGFFDLIAVVAGCVQTVLYCDFFYLYITKVL KGKQLSLPA--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------KRQGRSDAYATEFDLEAEEYVPLPKGDVHKK KEVVQDVTLHDLDVANARPQGGQDIMSMMGQLMKPKKTEITDKLRKEINKIVNKYIDQGI AELVPGVLFIDEVHMLDIECFTYLHKALESTIAPIVILATNRGKCLIRGTE--------- -DLLDRLMIVRTLPYSSEEMSMIIKIRAAVEEVPVTDEAVQKLSQIGTDTTLRYAIQLLT PSFNLAKINGKTTVSPEEVTEISELFHDAKTSAKLLASMGDKYMKXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMTYQLYRNTTLGNTLQETLDDLISSQVISPNVALKVLQQFDKSVSEALSHKVRTRLS FKGSLVTY-------------------------------TFLFTSESVGEGHPDKMCDQI SDAILDAYLKQDPNSKVACECAAKTGMIMLLGEITSKAHVDYQKVVRDAIKHIGYDDSNK GFDYKTCNVLVALEEQSPDIAQGVHVGRDDDDIGAGDQGIMFGYATDETKECMPLTVILA HRLNEKMAELRRDGGLPWCRPDSKTQVTCEYKTINGACVPQRVHTVVISVQHSDDISLKE LRADL-EKVIKTVIPEKYLDSKTVFHLQPSGRFVIGGPQSDAGLTGRKIIVDTYGGWGAH GGGAFSGKDFSKVDRSAAYAARWVAKSLVHAKLCRRVLVQVSYAIGVSRPLSVFLTTYGT GIMSDA----------------------------------------------------MA GAALKRLVAEYRQLTQNAPEGIVAGPVTEENFFEWETLIMGPQDTCFEGGVFPAKLWF-- ------------------------------------------------------------ ------------------------------------------------------------ -----------FRFCTGRCNKLFKKKRNPRKAKWTKAFRKSSGKELTVDPVFEFEKKRNI PVKYDRDLWRKTVAAIKRIDEIKEKRQNKFISDRLKVGKQLRKESELKAVEKGIHLIRT- ------YTIVMIRHGESQWNKLNKFCGWFDADLSETGIEEAKAAGKVLKEKGFMFDIAFT SVLKRAIKTLYLVQDELDLHWIPVTRCWRLNERMYGGLQGLNKAETAAKHGEDQVKIWRR SYDIPPPIMDESNDMLPSKDGRYSYVDASLLPKSECLKDTVERVLPFWHDSIVPQILAGK KVLISAHGNSLRAMVKYLDNVGDQDIVGLNIPTGIPLVYELDENLKPVNHYYLADEATVK AAEAKVANQGKA-MELSNIHYVKTDYVETASGNKVGRNCTLCGSQNIIIQGKTILVDECM LRGDLANIKVGRNCIVGRGTVIRPPFKKFSKGVAFFPQTIGDHTYIGENSVVMAAQIGSY VKIGRNCVIGKRSVLKECCEVADNTVLPPETVVAPFTKIEGIPGMSFLFPSRSNKTFRPK KNIPEGTHQYDLMRHAAATLGSGNLRMAVILPEGEDVNEWIAVNTVDFFNQINMLYGTIT EFCTEIKCPVMSAGPKYEYLWADGHTVKKPIKCSAPKYIDYLMTWVQDQLDDETIFPAKI GVPFPRNFMNISKTILKRLFRVYAHIYHQHFSEVCTLQEEAHLNTSFKHFVFFVQEFNLV ERKELAPLAELVQRL----MGKDIRHNKDRKVRRAAPKSPNNYLRLLVKLYRFMARRIDS NFNKVVLRRLFMSRIN-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------ISVTLIPDSSIYAMMSRVNKVII GTHTILADGGLKAIGSRSLALTAKYHSVPLIVLAPTFKLSPHHSHSQLESMNKMMCPEKI YNPVFDLVPSNLVTLFITNNGGNAPSYMYRLLSELYHXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-SPDPVEGRKHMDVQT ELYLEELSDRVEEADVDCQTDPFLDRPPTPLFIPAKTGLDVATQILEGDLFDFDIEVKPL LEVLVGKTIEQSLIEGMEEGELANLRKQQREFMELRNAE-------EEQERRHREEKERR MEQQMEVIRIEKETTEKIAARAFAQSYLTDLVPSIFGTLAENGFFYDPVERDIEQDFMMN LENAVLTRIDERILSRALVDDLIREVVRQRREEFQKMKAQGLLKRYVVVGRKLKKDEDEE NPLYKMILFAPNSVVAKSRFWYFLSKQIKFKKTKGEIVHVSCVPEKHGASLKNFGVWLRY DSRSGTHNMYREYRNLTQAAAVTECYRDMAARHRARSHSIQIMRVEEVAFNKVRRPHIKQ FNNVKMSFPLPIKRNKPFNYKK-------------------------------------- ----------------------------------------------------------FG ISYHSLNGLRHLYWDFKGGYEMRDQYKSGYFICASLTY-RPPVILSEYRDQHMRASRDDQ QRLLYNSTTLYVGNLSFYTKEEQIHELFSKCGDIKRIIMGLDKVHKTPCGFCFVEYYDQD SASYANAYISGTRLDERIIRSDWDTGFVEGRQYGRGKSGGQVRDEYRKDYDSGRGGLGKI IQNQM---YSLKYTLAGHTKAVSSVKFSPDGEWLASASADKLIKIWGAYDGKFEKTISGH KLGISDIAWSSDSSLIVSASDDKTLRIWDVAAEKSLKVLKGHSNYVFCCNFNPQSNLVVS GSFDESVRTGKCLKTLPAHSDPVTSAHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG KWIVCGSEDHQIYIWNLQTKEIVQTLSSHTDVVLCSACHPTENIIASAALENDKTIKLWR SD-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMAVEFAGGVIMCADSRTSAGSYIV NRVTDKLTEVYDRIYCARSGSVADTQAVADMVKYYLDYTSAVMEKEPSVKMAASMFRNLC YQNRDNLSAGIICAGWDAKLGGQVYSVPIGGMLSRQPFTIGGSGSTYLYGHVDRTFKQGM TRDECIQFCKESVALAMSRDGSSGGVIRLAIIDEQGTERRVYCGDEIPRFAAIAIGAVLL LLCCCICICKKCCKRRKKKDGKKG-KGGVDLKGVSLLGGSYKEKVQPDMEELEVNMEDNE DAESNKSEPKLGKLQFSLDYEFNKGELTVGVIQGTELPAMDMSGTSDPYVKTYLLPDKKK KFETKVHRKTLNPVFNETFTFKVPFAEITGKTLCFAIYDFDRFSKHDMMGIIKIPLNSID LGSVYEAWHELSDPETDAEKENKLGDICFSLRYVPTAGKLTIVILEAKNLKKMDVGGLSD -------------------------------------------QKVTVHITVVDYDRIGT SDAIGRCVIGVNSTGSELRHWSDMLANPRRPIAQWHTLQEVPEK-MVLADLGRKITTALR SLSSATVINKDVLQELLKDVCKALLEADVNVKLVKRLRENVMAANNFEEMAAGINKRKMI QVSVYKELTKLVDPGVKNWTPTKGKTNIVMFVGLQGSGKTTSCTKYAYYYKRKGWKTCLV CADTFRAGAFDQLKQNSTKAQIPFYGVDTSGRHKQEESLFEEMLMVNNANPDNVVFVMDA SIGQACESQAQAFKSKVDVGSVIITKLDGHAKGGGALSAVTHSPIIFIGTGEHLDDFEQF RVQPFLSKMLGMGDITGLVDKVNELNLNDEALVKKLKQ---------------GVFTLRD MYEQFQNIMMSILEYNGGTVVGMTGKKCVAIASDMRFGIQLQTITKDFQKIFKFGDKVYL GLSGLATDVQTVSSRLMFRKELYELREYREMKPKTLMNVVSGLLYERRFGPYFVDPIVAG LD-KDNEPYIASSDLIGCSCQFSDFAAVGCSSEQLFSICEAYWKPDMNPDELFETISQAL LNAVDSTANSGWGAEVYIIEPNKVTRREIKVRQDMTSKDYYFDSYAHFGIHEEMLKDEVR TMTYRNAMXHNRHLFRGKVVLDVGCGTGILSMFAAKAGAAKVIAIECSSIADSAVKIVED NNLSDVVKILKGKVEEVTLPDGIEKVDIIVSEWMGYCLFYESMLNTVLYARDKWLAPNGL IFPDRATLMLCGIEDRQYKDEKINWWENVYGFDMTSIRKTAISEPLVDVVDQKQIITNSC LVKEVDMYVVKEEDLAFSSPFQLSCMRNDYIHAIVAYFKIEFSCCHMRTRFSTGPEARYT HWKQTDDYLTVKKGEVLDGAITVKPNKRNVRDLDFTISVNFSGELSQISETNNYKMR--- ------------------------------------------------------------ -----------------------------------------------ALAPLDVFVPPGN TGMGPDKTSFFQALAIQTKITKGMVEIINEVHLV-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------YQKTLPAVLEIPSKDSPYDP AQDSILRRAKGMFSAEDFRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXLYREVKLYDNARERERYDNMAELYSVINTLQCLEK AYIKDAITAKEYTANCSKLLMQYKSAIKQVQG-EFRTVEEFVKKCKLNCPAALERIKEDR PITIKDDKGNTSTCIAAIVSLFITIMDKLRLEIRANDELLPDTEELIDTINRLSMVPADW EGRQLTTKWVSTLKAMPASGELSDEQVRQMTLDLDLAYNSFSRLLQNXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XX---------------------------------------------------------- --------------------------------------DDMAEAMKGVAKAMSKMSRQMK LPQIQKIMMDFEKQLEIMDMKEEMMSDAIDDAMGEEGDEEEGDVKVKDVLKELGLDL-XQ LSGIPAASGETSKQPVAVNAEDADLEARLE-------YCDFCLGDTIENKKTGQKEKLVS CADCGRSGHPSCLQFSDNMIISVRKYPWQCIECKSC------------------------ --------------------------TMDKTIQLYPLTNYSFGTKEAIPEKDSSVVIRFQ RMRDEYEKHGMRRSVEGVLIVHEHNLPHVLLLQLGNAFFKLPGGELDQGEDAVSGLKRLL TNTLGRQDGLPIDWAVDDVIGNWWRPWFELSQYPYIPAHVTKPKEHKKMFFVQLPKKAQF AVPRNYKLVAAPLFELYDNGNGY-------------------FTPSGTTPIGNKAMGMAT PTPGHV--MSAEQMLAYTLQREIDERNRPLTDEELDVMFPPGYKVLQPPAGYIPIRTPAR KLTATPTPIAGTPAGFRMQNSIPDLRPKGMQVEVKPDDMQYFDIRIMRHLFKIKNGTPPM RKAALRQITDKAREFGAGPLFNQILPLLMSPTLEDQERHLLVKVIDRIMYKLDDLVRPYV HKILVVIEPLLIDEDYYARVEGREIISNLAKAAGLATMISTMRPDIDNMDEYVRNTTARA FAVVASALGIPALLPFLKAVCKSKKSWQARHTGIKIVQQISILMGCAILPHLRSLVEIIE HGLVDEQQKVRTITALALAALAEAATPYGIESFDSVLKPLWKGIMQHRGKGLGAFLKAIG YLIPLMDAEYANYYTREVMLVLVREFQSPDEEMKKIVLKVVKQCCATDGVEPQYIKDEIL PPFFQHFWNQRMAADRRNYRQLVDTTVEIANKVGAAEMIRRIVDDLKDEAEQYRKMVMET IEKVLSNLGSTEIDSVLEEQLIDGILYAFQEQTTEDVVMLNGFGTVVNALAHRVKAYVPQ ICGTILWRLNNKSAKVRQQAADLISRIAIVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLG SILGALKSIVNVIGMHKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGSEYVS AREWMRICFELLDLLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVC TTVAIAIVAEICSPFTVLPALMNEYRVPELNVQNGVLKALSFMFEYIGEMGKDYIYAVTP LFEDALMDRDLVHRQTAMAAIQHLALGVYGFGCEDALIHLMNNVFPNIFETSPHVVQAFM GAVEGMRVALGPCRVLQYIQQGLFHPARKVRDVYWKVYNTIYIGGQEALIMAYPRLENDE KNAYVRYELDYVLGDFMCEDEEYDLEYSEDSNSEPDVDLENQYYNSKALKEENAQRALES FQKVLDLENGEKGEWGFKALKQMIKISFKLSDTHEMMKRYKELLLYIKSAVTRNYSEKSI NSILDYISTSKQMELLQEFYETTLEALRDAKNERLWFKTNTKLGKLYFDRGEFIRLHRIL KQLHSSCQTDDGEEDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLQIKSAIPHPL IMGVIRECGGKMHLSEEEYEKAHTDFFEAFKNYDESGSARRTTCLKYLVLANMLMKSGIN PFDSQETKPYKNDPEILAMTNLVSAYQNDDIKQFEGILKENRTNIMQDPFIREHIEDLLR NIRTQVLIKLIKPYTRIHIPFISSELNIDASEVESLLVSCILDDVVSGRIDQMTQVLELK SPPNLYRAIDKWTTQLRSLQETVTNKLSVLLMGKNGSGKTSMRSIIFANFMARDTRQLEA TIGVEHAHVRFLGNLVLSLWDCGGQEQFLEDYFQSQRDNIFRDVKVLIYVFDVESRDLDK DMHYYQSCLENIITYSKDAKVFCLIHKMDLVQEDQRDTIFRERQIDLIGLSKPLATSIWD ESLYKAWSHIVYQLVPNVDSLERRLTRFAQLIEADEVILFEKATFLKISHYERRQHPDPQ RFEKISNIIKQFKLSCSKLATSFESIEVRNSTFAAYIDVITPNTYIMVVTSDKTTTSALM QLNIKNARKHFENIER-------------------------------------------- -------------------------------------------IRNICVFLAPFFSSLTV FATYFLSRELMDTSAGLVAAALLSVVPGYISRSVAGSYDNEAIAIFCMLTTYATWVRSVK TGSVAWASVCAICYFYMVSSWGGYVFLINLIPLHVLALMICGRFSHRIYVVYCTVYCVGT ILSMQISFVGFQPVQSSEHMAALGVFGLCQIVGVYKYLQSKLSKEQFSVLFRALVILGST AVAMALGKIAPWTGRFYSLLDPSYAKNNIPIIASVSEHQPTCWSSFYFDFQFLVFTFPVG LYYCFKNLTDQNIFIIMYGTSSIYFAAVMVRLMLVLAPVMCILGGIAVSGILKSYMPYVE LKAAADSSYPFRNEVASGVVLILCVCMMTYAFHCTWVTSEAYSSPSILLSARSHNGGRII FDDFREAYYWLRQNTPEDAKIMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMAS PEQHAYGIMRELDVDYVLVIFGGLIGYSSDDINKFLWMVRIGGSTDRGAHIKEADYYTSS GEFRIDSEGSQTLLNCXMYKLSYYRFGSMYTDQSKPTGYDRVRNAEIGHKNFDLEVVDEA YTTEHWLVRIYKVKKPDNRG---------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---IKAFIPAIDSFGFETDLRTHTQGQAFCMSTFHHWQIVPGDPLDKSIIIRPLEAQPAT HLAREFMVKTRRRKGLSEDVSINKFFDDPMLIELAKQ--------QEIFQLYDLTGDGFI RGDQLGQVIRACGENPTESDIKRY--DSDRIDFDQFLPVLRAIRQAAVEPPLEEFIEGFK VFDKEGNGTISAAELRNLLGTLGEKLSPEDMEQLLAGQIDNNGYINYQDFIRTVLS-MSC MTFNIDNGYLEGLVRGFKAGILKQGDYLNLVQCETLEDMKLHLQSTDYGSFLSNEASPLT VSVMDDRLKDKLVVEFQHIRNQAVEPLSTFLDYITYSYMIDNIILLITGTLHSHPIADLI ARCHPLGSFEQMEAIHIATTPAELYNAVIVDTPLAPYFIDCISEQDLDEMNIEIIRNTLY KAYLEDFYKFCMQLGGATSDVMCEMLAFEADRRAFIITINSFCTELTKDERSNLYPRCGK LYPDGLASLARADDYEQVAALASFYGDYKGV--------------------EVNLMKNAF LXNFHFGVFYSYVKLKEQECRNIIWIAECVAQKHRTKIDSYIPIFSPRKAVRKISKIPFK VLDAPELQDDFYLNLVDWSSQNVLSVGLGTCVYLWSASNSQVTRLCDLSCDGDTVTSVSW ADRGNLVAVGTHKGHVQIWDVAATKRISVIEGHTARVGALAWNADMLSSGSRDRLILQRD IRTYQNTPEKRLTGHRQEVCGLKWSPDRQQLASGGNDNK--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------VLLIIALYYLFTGQGYAIDIGWFLTETSPYLWANLGVAFAITFS VVGAAWGIFTTGSTILGAGVKAPRIRTRNLISIIFCEAVAIYGIIVAIIIGNQQNYIAGY SMFGTGLTVGLTNLASGVCVGIVGSGAALADAQHPSLFVRILIVEIFGSAIGLFGVIIGI MQSSRFKMG--MAASRRLKKELTEDAEDDNILKWIVTLSPDHDPYKGYLFKLHIEYPAEY PFKPAKICFKTPMYHPNVDEKGQVCLPIIDTENWKPATRTEQVLSSLLDLIKNPAVDHPL RADLAEKYNQDKSAYMKLAVAFTKKHCEK----GASKVYPKQCSALRKNEFVVIKNCPCK IVEMSTSKTGKHGHAKVHLVGIDLITGKKLEENCPSTHSMMVPVVNRTEYDIIDISDGFL SLMHENSSVREDLNM--------------------GILSGPKGVCVNSEGQIIVVDNRNC SVCIFLPNGKLLRKFGSRGSHQFSAPHFCAVNSQNDVFITDFNNHSVKCFDHGSFRFSFG SVGSGNGQFNSPTGIALDSRDHIYVADWGTARIQAFDEKGNFLSHVNLWGPQGLAVNPTG QLYVADSGHHCVKIFQ-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---YLCNRAITISYAFKKDAKGERHGTPAERLLAAQNPLTQADQPHQLFADAPPVAPPAP LIPPP-PPVGML---PPPHMMG-------------------------------------- --------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------SSFSEAMRIGAEVYHNL KSVIKKKYGQDACNVGDEGGFAPNILDNFEGLELLKLAIAKAGYTDKVEIGMDVAASEFC KKYDLDFKNKETDPATHLSSDALADVYKKMIANYPVTSIEDAFDQDDWDAWTKLLAVQLV GDDLLVTNPKRVKTGIEKKSCNCLLLKVNQIGSVTESIEACLLARSAGWGTMVXHRSGET EDNFIADLVVGLATGQIKTGAPCRSERLAKYNQILRIEEELGDKAVFAGRKFRNPQGPPT AGAFQQRQQAVTNFRKFYERGDFPIALEHDTKGNKIAWKVEIEKLDYHHYLPLFFDGLRE VSHPYEFFARQGVHDLLEHGGGKILPVIPQLIIPIKDALNSRNEQVICTTLKILQQLVVS ADMVGEALVPYYRQILPVLNIFKGKNKNTGDGIDYGQQKRENVGDLINETLEAFERTGGE DAFINIKYMIPTYESCLMNAPSTFESFLLFDGEKKIQIEKETKVPNAAIFIINKEDHTIG NMIKTQLMKNPNVIFAGYKVPHPLEYRVIIRLQTTDSTTPQEVFTEAIKDLISEFSLLQE KFDEALRDRRELD-DHRRKWDRDEYEQQAKSRLDAEEDEDERPIKRALLKPREYKVDLDS NLGKSQMIQRTAPTSQQGGYYCNVCDCVVKDSINFLDHINGRKHQRNLGMSMKVERSTLA QVKARFEAIKKRTE---------------------------------------------- --------------MGCSMSSDERVAAERSRAIEKNLREDGIQAAKDIKLLLLGAGESGK STIVKQMKIIHEGGFTTEDNKQYRPVVYSNTIQSLVAIIRAMGTLSINFDSPDRESDAKM VLDVVARMHDTEPFWEDLLDAMRRLWADTGLQECFGRSNE-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------MIGSIGIFEIKGCRKGPAEDIIDQAFKYFRPNLYFKKFEFETKSDGVFVYLML YIAECVKSLAKCPNKKEGVKAMQTLAIREFAIPGDSNFPLNAFYT-PYKPAEKDNLLNYL KQLRNETGRRLCDKVYADDSCPPSKWWTCFKTYKFCNNTL-----AGPYNYSYIFKYIII GDMGVGKSCLLHQFTEKKFMYDCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVT RSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIFLIGNKSDLDAQRDVTYE EAKSFADENGLMYLECSAKTGENVEDAFLDTASKIYQNIQDGSLDLNAAESGVQHKPMAP RTTLSGDQAPAKEGCMC----AVCVFGSSGVKGTINFTQDGVVKCSGEITGLTPGEHGFH IHEYGDNTNGCTSAGAHFNPFSKNHGGPKDSERHVGDLGNVQADKFDIKDEQLKLTGIHS IIGRSVVVHEGVDDHGKGGHSDSLTTGHAGGRLACGVIGIS-MVNFTVDQIREIMGNSTH IRNMSVIAHVDHGKSTLTDSLVSKAGIIAGSKAGETRFTDTRKDEQDRCITIKSTAISLY YEMNRADMQPGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQA IAERIKPILFMNKMDRALLELVLEKEDLYQTFQRIIESTNVIIATYADEDGPMGNVMVDP TKGTVGFGSGLHGWAFTLKQFAEIYQDKFKIDTHKMMKRLWGDNFFTAVRGFCQFVLDPI YKVFKFAY-KEKVFGMVEKLGVKLTVEDKELCDKPLLKTIMRKWLPAGETMLQMIAMHLP SPAQAQKYRCELLYEGPQDDAAAVGIKSCDANAPLIMYISKMVPTTDKGRFYAFGRVFSG TVATGQKARIMGPNFVPVKSIQRTILMMGRYVEAIPDVPCGNICGLVGVDQFLVKTGTIT TFEAAHNMKVMKFSVSP------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ LPLSLLRTAVNHPILVEIKNGETYNGHLLNCDNWMNIHLGEVICTSRDGDRFWRMPECFV KGTTIKYLRIPDEVIEMVKEDTA-ANRGFSSGRMRGRG---RG--GGRGG--PPRGRG-- ---TEIDLPNAPGDQISNVEFHPNNSKILLASSWDSTLRVYD--GTSMQFKLDFPSPLLD CCFKDGNVVFAGGLGYELVSLDLTTRIVRPLGMHTSVIKCVEHEKDTGLVITGSWDSTVK LWDPRTQAAVGTHKQPDRVYSMSSCGERLVVATAGRRVLIWDLRNMGIVQQRRESSLKYQ TRCCKTFPNGQGYVLSAIEGRVAVEYFDPDPEIQRGKYAFKCHRLKENGVEEIYPVNTVA FHKEYNTFATGGSDGFVSIW---------------------------------------- --------------------MDFQHRAGGKTGTGGVASASDANRDRRERLRQLALETIDL NKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQANLSRRAAKEAKEAQIQPAPE KARVDIKKFV-------------------------------------------------- ------------AEPYETIGFKVPSREVDKGEGKFWVHWNKETKQFFLQFYYRHLTSAVQ PPP--------------------------------------------------------- -------------------------VFFPDEPKVSVKCMKTYFARMQAENIHRAILVVQH GFTPSAKQGLIDLMSRYTVEQFHENELLINIIEHSLVPEHVVMTPEEKKELLARYKLKES QLPR--------------------------------------DEKDDVGTVIGIDLGTTY SCVGVYQNGRVEIIANDMGNRITPSYVAFTEESERLIGDAAKNQLTSNPENTIFDAKRLI GRLWNDKSVQNDVKFFPFSVVEKGGKPQIKVKQGTVDKQFTPEEISAMVLQKMKETAEAY LGKKVTHAVVTVPAYFNDAQRQATKDAGTISGLIVMRIINEPTAAAIAYGLDKKDGEKNI LVFDLGGGTFDVSLLVIDNGVFEVVATSGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRK DNRAVQKLRREVEKAKRSLSATHQTRLEIESFFEGEDFSEVLTRAKFEELNMDLFRSTLK PVKTVMDDADLKK----------------------------------------------- -------------------------------------------PTKKSQIFSTAADNQQT VTIQVFEGERSMTKDNHHLGKFDLNGIPPAPR---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------EEEAEKLKEMQNEVEKQMSVDEKVEADARSV YVGNVDYAATAEELEQHFHGCGSVHRVTILCDRYSGHPKGFAYIEFA------------- ------------------------------------------------------------ ----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXVKVGINGFGRIGRLVLRASLKQVQVVAVNDPFITTDYMVYMFKYDSTHGR FGGTVELVVDGNAIAVHQAKNPAEIPWGADGVDYVVESTGVFTSLEKAQAHITGG----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------TDPEPYCIVAPETVIHCEGDPIKREEEEESMNELGYDDIGGCRRQLALVK EMVELPLRHPQLFKAIGVKPPRGILLYGPPGTGKTLLARAVANETGAFFFFINGPEIMSK LAGESESNLRKAFEEAEKNAPAIIFIDELDSIAPKRDKTHGEXERRIVSQLLTLMDGLKQ RSHVIVMAATNRPNSIDAALRRFGRFDREVDIGIPDAVGRLEILRIHTKNMKMSEEVDLE AIANESHGHVGADLAALCSEAALQQIRGKMDLIDLEEDVIDAEVLDSLAVTMEDFRFAMS KSNPSALRETTVEVPNVTWADVGGLEKVKHELQELVQYPVEHPEKFLKFGMTPSRGVLFY GPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVREIFDKARQAAPCVLFFD ELDSIAKARGGSAGDGGGAADRIINQLLTEMDGMGAKKNVFIIGATNRPDIIDSAILRPG RLDQLIYIPLPD-XCRKQILRANLRKSPVAQDVDLSYLAKVTEGFSGADLTEICQRSCKL AIRQSIEADIQRRREAKDD-EEEDPVPFISRSHFEEAMRFARRSVTDNDIRKYEMFSQTL QQSRGFGN-----------------------FQVTSPPEDTVSSMAFSPPSIPTSFLVAG SWDNNVRCWEVQQNGTTVPKAQQSHAGPVLDVCWSDDGQKVFTASTDKTAKSWDLATNQF VQVAQHDAPIKTCHWIKAPTYSCLMTGSWDKTLKFWDTRSSSPIMTIALPERCYCADVVY PMAIVGTAAKDMIVYQLDGQPKEYKKMESTLKYQHRCVAIFNDKKNPMPHGFALGSIEGR VAINYVNTANPKDNFTFKCHRAQTQEIYAVNDIAFHPIHGTLATVGSDGRFSYWDKDART KLKNSDQYPAPITTCTFNHNGEI------------------------------------- ---MSSPSPGKRRIDTDVVKLIESKHEVTVVGGLSEFIVKFYGPENTPYFGGVWKVRVDL PDKYPFKSPSIGFMNRIYHPNIDEVSGTVCLDVINQAWTALYDLTNIFDTFLPQLLAYPN PVDPLNGDAAAMHLHKPDQYDLTVKDYIKKYATEEILRDQESSMSDFSEDEAADMELMVD SDITTTLKIVIVGESGVGKSSILMRFVSDVFESDICVTIGVDFKVKNLNIDGNKVKLAIW DTAGQEKFRTLTPSYYRNAQGAILVYDVCSRDSFDRIAAWFNELETYSNKQDIVKMIVAN KIDKDDRVVSRTEGIEFARKHRCLYIETSAKTKEGVDCAFEELGEKIIQTPGLWESDGFN VASVIFDILNHGHCSYKIKTVSRTFCRNEYNLTGFCDRGSCPLANSRYATVREENGIVYL YKKVPERAHQPEKLWEKIKLPKSFKLALQMISSELEYWPRKLINKCKQRLTRIAQVLIRM RKLKLKRQKKIVPIHSKVEKVEKRREMKALVAARLEVSIEKELLERLKNGTYGDIYNFPQ STFEKVLDEEVEKEEEELEREVEYVADEDVEGLFDSDSD--------------------- ------------------ECGPMVLDALIKIKNEMDPTLSFRRSCREGICGSCSMNINGL NSLACLCKIDE--VKEIKILPLPHMYVVKDLVVDMSNFYAQYKTIEPYLKADPKPEGQ-- TTEYIQSKADRAKLDGMYECILCACCSTSCPSYWWNQDKYLGPAVLLQSYRWLMDSREN- -------------VYRCHTIMNCTKACPKGLNPGAAVAGIKRMLNG------------PT HTIYINNLNEKIKKEELKKSLYAIFSQFGQIVDITALKTLKMRGQAFVIFQEMSSATSAL RSMQGFPFYDKPMRMSYSKIESDVIAKAKGTYVDRPWIDRTS-EKKKKKAGPMANFENET PNNVLFLQNLPDNTTDVMMSMLFNQFPGFKEVRLPPGMSHIAFVEFDNDTQAKTAKDSLQ GFKVNPTNEMNITFAKK---------------------------PSHIFPAMVGRPIMRS DTKSKEVVVKDIMVGDEAAQCRRFLDIKYPMENGIVQDWENMGHLYDYTF--QRMGVETR GSKILLTEPPFNPVPKKKKLFELMFEKYGFHGVCCQIQGVLTLYAQGLQTGLVVDSGDGV THICPIYDG-AVTGKTNRLNIAGRHVTSYLIKLLLLRGYSFNKSADYETIRQLKEKLCYV GARPEVEMQLALNTTVLVKKYTLPDGRVISVGSERFQAPECLFQPNLVDVESPGVAQLVF NTIQSSPMDTRQDLYKHIVLSGGSTMYPGLPSRMEREMKQLYLQEILKGDVSRLSKFKLN IECPPRRKHLVFMGGAVYADIMKDMDAIWLTKKHYEEVG--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GCKKAGASRVIGVDINPDKFEIAKNFGFTEFVNPKALER STKDVLIEMTDGGLDYTFECIGNVNIMREALESCHKGWGVSTIIGV-------------- ------------------------------------------------------------ ---NIMVNQPVVIDNGSGLIKAGLAGDQVPKCHFSNYVGTPKHVRVMAGGLEGDSFIGPK AQEHRGMLSIHYPMEHGIVTDWNDMEKIWQYLYTKEQLNCFPEEHPVLL----------- ------------------------------------------------------------ ------------------------------------------------------------ ----------GSSRFRAPEVLFRPHLMGSEELGIHEVLSHSIQKSDLDLRKVLYSEIVLS GGSTLFKGFGDRLISELKRLAPPDNKIKIS------------------------------ -------------------IDKVVVHPLVLLSVVDHFNRMCKTGATKRVVGILLGSDKNK VLDVSNSFGVPFDEDDKDNSVWFLDHDYAETMASMFRKVNAKEKIIGWYHTGPELRPNDR TINELIRNYNPNSVLVVISTQNKKGGLPTEAYIAVDRVSDDGKLTEKTFEHLSSEIGAEE AEEVGVEHLLRDIKDLTVGSMSQKMDTQMSSIQSFLSKQGDVAAYVQKVLDGKLPMNYDI FYLLQDIVNQLPDVSQHDFVRSSNVKNNDTMFLLYLASLCRSVDAMHDLIQNKLQNRESD DLLTKSKEMGILFTKLWNMFSKEEHKIIIVGLDNAGKTTILYQFLMNEVVHTSPTIGSNV EEVTWKNIHFLMWDIGGQELLRSTWSTYYANTEFVILVVDSTDRERLSIAKEELYKMLAC EDLKKAAVLIFANKQDIKDGMTAAEISTHLNLTSVRDHVWHIQGCCALTGRGLYDGLEWI VNTLKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRKFSTTNKVA VLGASGGIGQPMSLLLKCNNQISHLALYDIAHTKGVAADLSHCSTQARVTGHLGPEELPE CLQNADIVVIPAGVPRKPGMTRDDLFNTNASIVRDLSIACAQHCPKAMICIICNPVNSTV PICSEIFKKHNVYDPKKIFGVTTLDIVRSNTFIAEQKGLDVTSVNCPVMGGHSGITIIPL LSQCTPPVSFPDDVHDKLISRIQDAGTEVVNAKAGAGSATLSMAFAGARFVDSLVQAICG EQGVVECAYVKSDETEAEYFATPLLLGPNGVEDNLGIGNWLSKESALLEKAMPELKANIE KGKKFV---IDQNKDFN------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------RFRELPAGIN SIVAIASYTGYNQEDSVILNESAVDRGFFRSAFYRSYRDAESKKGFDQEEIFEKPDRSFV TGMRPAMYDKLEDDGIIAPGIRVSGDDVLIGKTVTIPSTEDDLKETTNRFAKRDASVFMR RTETGVIDQVMVTINEEGLKFCKIRVRTVKTPQIGDKFASRHGQKG-------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------IAHGAAQFLRERLFEASDPYRVHVCNLCGLIAVANLRNKTYEC RGCKNKTQISQVRMPYACKLLFQELMSMSIAPRMMVLCIESSGGFSFDNCRRNALLEQNI IPKKAKKTGTTIVGLIFKDGVVLGADTRATNGSIVEEKNCEKIHYLAENMRCCGAGTAAD TQVTCELISSQIRLHRQQTRRTPRVITASRLMRQMLFRYQGHIGAAMIIGGYDCNGPHLV SISPNGSIMTVPFTTMGSGCLAALSMF--------------------------------- -----------------------------------------------------TKVSFKI TLTSDPKLPFKTVSVPEQTPFTAVLKFVAEQFKVPPATSAIITDDGIGINPSQTAANVFL KHGSELRLIPR-----MALNFAAICYIIALILCAVLLFFVIYHIIAFDELKTDYKNPIDQ CSSLNPLVLPEYALHTLFTVLFMFSGELFSFVVNLPLVIYHVYRYANRPMMSRPGLYDPT SILNSDNLNRAMKEGWIKLAFYLISFFYYLYSMIYCLVSAMGLLTILKKMKQKEKSVRIL LLGLDNAGKTTILKKFLGEDITTISPTLGFSIKTLEHNGFQ------------------- ------------------------------------------------------------ ------IKTHHWCILPCSAVTGKNLLDGVDWIINDISSRIFTVDTEKKRVCYYYDGDIGN YYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATQEEMTKFHSDDYIKFLRSIRP DNMNEYNKPMQKFNVGEDCPVFDGLYEFCQLSTGGSVAGAVKLNKQQTDIAINWGGGLHH AKKSEASGFCYVNDIVLSILELLKYHQRVLYVDIDIHHGDGVEEAFYTTDRVMTVSFHKY GEYFPGTGDLRDIGAGKGKYYAVNFPLRDGIDDQSYELIFEPVMSKVMDHYQPNAIVLQC GADSLSGDRLGCFNLSLKGHGKCVEYMKRFNLPLLLLGGGGYTIRNVARCWTYETSIALG VEIANELPYNDYFEYYGPDFKLHISPSNMANQNTIDYTDKIKSR-XENLRMLPHAPGVQM QNIPEDSLNMDTSEKQRISIRDSDKRITGETEFSDSEDE--DGRRDNENHRNKKRKEGIF ECNICFDTATDAVVSNCGHLFCWPCLCRWLETRPNKQMCPVCKAGISRDKVTPIYGRGS- DKKDPRDKVPPRPQGQRSEPAYQHPFAGMGFGLQMSFGIGAFPFGFIASSFNLNDGRPPA PAPGTAQHTEEQFLSKVFLWIAMLFMFWLLI-MYTSVHKEENGHNDSIWSCAWGRNENTG QDCIITGSVDDTVKIWHWQNLQQKHLLEGHALGVVCVDINANGTMAVSNSLDANLRLWDV ESGQLLKTIDAGPVDAWWCRFSPDSELVATSSYTGLINLFSVKSGEKISYLDTTGKFVLS IAYSPNGKYIASGAINGIITIFDVATKTPLDGHAKPIRGLCFSPDSQLLATASDDAHVKV YDVKSAT----------------------------------------------------- -----------------------------ETDEQFDTRMLAFFQNPKLDGWELRQGLNDI QQYDVVPEPTIIIAAMKACRRLNEYSLCVRYLEAVQDKCGRLKGEIWPWIHQEIKPALDE LGVATPEEMGYDKPELAV-------VKVIGLPWSVTKEDIVEFFPDVNIVDGLEGIHIVL DEFKRPNGHAFIKVASDSDIDRAREKHKARMKERWIEVYSARVDFMEYAMLRDKPNPTCI LALEGLPFACQIEDIIKFFYGFSIIPNGVTLIYDANHRCSGDAYVQFPDAETAERARKKK KQKIGHRYIDV-----------------HAIYMRGLPFDCSEADVYKFFAPSVPMRVKFV LSQGRPIGEADVEFATHEQALEAMKKDKQYIGKRYIWLFYKNKEKPQATRLSNITAGKAV ADAVKTSLGPKGMDKMIQDAKNNVTISNDGATILKKMRVMHPVARMFVELSKAQDVEAGD GTTTVVVLAGSLLESCKQLLEKGIHPMVLSECLQRVVEKSDEILQDMATPIDLKDRAALL RIAETSLNSKVVSQYSSILAPLCVDAVLGCMKHSEDTNVDLRDVRIVKAIGGTVDDTELV DGLVLDQKVI--SSIKRVEKAKIGLIQFCISAPKTDMDNQVVVSDYSQMDRILKEERNYI IKIVKGIKASGCNVLLVQKSILRDGVSDLAIHFLNKAKIAVVNNIERDDIEHISKTLGCR PVASLDHMVAEALGSAELFEEMTIGATKLSKFTGMSSAIPTKSLLITASNELLLEEADRS LHDALCVIRCLVKNRAVVSGGGAAEIELAVKLDEYSRTLSDVNQYCFHAFAAAFEVIPYI LADNAGMDPILSITQLRNKHSAG------------------------------------- -----------------LLDIKSAAIYETLISKFEEVEDG-KVHSSDATISHFQ-CTYHI KSSDEDRSKIRVSVRLQADTDFSGNEFDTYFKRLYEPYVVSTEDGYTRSIQYPMETREKA EKVATLFALLYRNCYAYFVKNAIKLQREAKIRKISLSNDQTMYIKPASDRVTAIFPFHYV SADDLTYGRVFIEGLKDSKERLQGVPQILYAEKEPPSELEGHEKRSEDT-GFFTIILQER HDNEEKAIDLLLLLRENFWFHINACKVNIHVWMRKKTNEFLKNINRARPDSQT------M LRFCPTCANILIVKEGERCYTFACNTCPYIFNITKKISKKQFPKMKEVDDVLGGAAAWEN VDSTEETCPKCSHDRAYFMQIQTRSADEPMTVFYKCCNMSCSHLWR-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------DVMMDFDALVA EQTGLGTAAVIVMNKQADLIQCIARLIEFYKHESCGQCTPCREGIDWMNKIMGRFVSGNA DTREIDSLYEISKNIEGHTICALGDGAAWPVQGLIRHFRPLLEERFAQYAAKD------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------ELNLIPTFIRLLYSAVENVQRVAAGVLCELAADKE SAEVIEREGATGPLTELLHSRNEGVATYAAAVLFRMSDDKPQDYKKRLSLELT------- -XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXX----------------------------------------------------- -------------------------------PKREVELATIESKWTDLSLSKARFDEIVR IGDFEDSVEWLLFFAIAASSLGDGLTQTMKKICEILTADKEGGPSRVNITVFEKLYSFLA KIDGEIEESKVEQVMTYLHSVKDEAD-MIQPSQFLHDDCPALS------QRTELMNNVKQ QVAAAQAQELLQKMSDKCFKKCIEKPGTSLSSSDQGCISKCMDRYFEVWNIVSQTYASRI QKEQ----------------------------------------------KYRDQMKKMR DGPAKNAVKQKALRVLRQRKQYENQRENLGQQSFNMEQSNMALQTMKDTQTTVSAMKLGV RQMKKEYKKINIDQIEDLQDDMEDMMEQ---IQEVMGRTYGTPEFDDEELEAELDALGDD LGLGEDTAYLDA--ISPSAPTNVPGESVPASEGGVKLDEFGLPQIGA---PMTPATPA-P HLQNIVCTVNLACKLDLKQIALQARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTG AKSEDMARLAARKYARIIQKLGFKAKFMDFKIQNMVGSCDVKFPIRLEGLLFTHGQFSSY EPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKVRQEIYDAFENIYPILKGFKKQEEEDD DDEYAIDIDVEHRDAGTADQFKWKVLTASEIVQHMVDCIKEVNAVVEIPATTTRILLSHF NWDKEKLMERYYDGNQEKLFSDARVISPFKKSSKSECEICLDQMTNMMTGLECGHKFCIQ CWTEYLTTKIMDEGMGQMISCAAHNCDILVDDSTVMSLVTDPTVKLKYQHLITNSFVECN KLLRWCPSPDCGHAVSVPYFDCRPVRCSCDHEFCFACGENWHDPVKCHLLRKWIKKCDDD SETSNWIAANTKECPKCCATIEKDGGCNHMVCKKCRADFCWVCLGPWEPHGSSWYNCNRF DETDAKKARDAQEKSRSALQRYLFYCNRYMNHMQSMKLENKLNAVVTTKMEELQQHNMSW IEVQFLTTALRVLSQCRLTLMYTYVFAFYLGKNNQSIIFEENQKDLEVATEQLSEYLERD LPSD-IADIKQKVQDKYKYCESRRNVLLSHVHEGYDRDLWVYQ------------DREVK STPKLPTKRLSMSDIYDSRGKPNIEKLKEHFVLEGRIEEEVAIRIIEDGAALLRKEDTMV NIDAPVTVCGDIHGQFFDLMKLFEVGGSPRTTRYLFLGDYVDRGYFKYSVKVYDKCMEAF DCLPLAALMNGQFLCVHGGLSPEIETLDDIKKLDRFKEPPAFGPMCDLLWSDPCEEFGTE KNQDRFTHNSVRGCSYFYTYAACCDFLQRNNILSIIRAHEAQDAGYRMYRKNQTTGFPSL ITIFSAPNYLDVYNNKAAILKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVT EMLVNLLNICSDDELTDEVVEEGEASIAQRKKVIRNKIRAIGKMARVFTVLREESESVLQ LKGLTPSGVLPAGTLSGGKASLKDVLQGSEGGIK---FEDAKMLDKFNERMPPRK----- ------------------------------------------------------------ ----------------------KIEYRAWNPFRSKLAAAILGGVENIWIKPGSKVLYLGA ASGTTVSHVADIVGKEGVVYAVEFSLRSGRDLVNMAKKRTNVVPIIEDARHPH------- ------------------------------------------------------VTKFRS EKVKPLEQITLEPYERDHAVFVGHYR-----MDPQKVKDFAGRLQRGGKGAGIGAGFLAA AGGLAYGLYNSMYTVDGGHRAIIFSRIGGIQKEIYSEGLHFRIPWFQYPIIYDIRTRPHK ISSLTGSKDLQLVNVSLRVLSRPDPSLLPDICRQLGVDVADRVLPSICNEVLKSVVAKFN ASQLITQRAQVSMMVRKNLMDRAKDFMIVLDDVAITELAFSPVYTAAVESKQVAQQEAQR AQFIVQKAKQERQQKIVKAEGEAAAAQLIGEAMAKNPGYIKLRKIQAAQKIAKTVAQSKN RVYLDAQSLLMNLSDSAYGD---------------------------------------- ------------------------------------------------------------ ------------------------------------------------NLILDDGGDATY VMLRSYPSCFSMIKGIVEESITGVHRLYQLSKTGQLKIPAMNVNDSVTKTKFNNYYACRE SVIDALKRTSDIMFGGKNIVVCGYGEVGKACCFALKSAGAIVMVTEVDPICALQACMEGF RVVKLSEVVKFVDIVVTCTGNRQVVSREHMDKMKHGCILCNMGHSTTEIDVASLRNCDLK WERVRSKVDHVIWPDGKRITIIAEGRQMALTCSTMPSFIISINSTTEALALIELFNAPPG RYKKDIYLLPKKMDEYVASLHLSNFSAHLTELNDDQARFLGVNKAGPFKPSYYRYPDPDA IKMFVGQIPRSLEEAELRTMFEEWGDVYQVNVLRDKITGSHRGCCFVTFYTRKSALEAQN ALHNIKTLPGMHHPIQMRPADSEKRNVEERKIFVGMLSKKCSENDVRTMFSPYGTIEECT VLREANAQSKGCAFVTFASRLSAQGAIKSMHHSQVMEGCRAKLVVKFADTQKEKEIKKMQ QSNSALQIQFTCGVVGGVTCAYVGQPLDTIKVKMQTFPEKYPSAVRCFSDTVRNEGGRGL YAGAVPSAENSVLFLAYGLCQKACAGAAFFSALALCPTELIKCKLQAVTAQILRAEGFLG LFRGFTPTLVREMPGYFFFFGGYE------------------------------------ -------------------------------------------------NPDLDYEKTAR EVSIKIQTISSNASTIQGLINRLGTPGDTAQVRTKLQNLQIETSVVSKETGGLMKQL-QA SSDYRQRKIKCERLASDFTTALNAFQSCQRLEVEKEKDGIDDLDYQIIEEREXAVLQLEN DIMNVNEIFKDLGALVHEQGEVVDSIEANVESTQVEAGRDKIQTAARYQNK--------- -------------------MVNVLKGTLVECDPAMKQLLLHLDEKLALGRKFIIEDLDET HLFISNDIIPELQSRIDQFMDKLSFDLGGKNQPTVSTPEAIQGLIATEELLRKKSSYLES QIDEQLKIAKRNVALAALKRKKRLEKQLEQIDGTLSTIEFQREALENSRTNTEVMKAMGS ASKALKQEHKVLDVDQVHDIMDDIAEQNEIATEIADAISKPFGVQSDIDEDELNAELDAL EEEEMAEQLMDVGTLPSVPSASDKDMEELMAWASSIQRFHNRVRQILMASGSTTFTKIVN KWNTVLIGLMTYFREAVVNTQELLDLLVKCENKIQTRIKIGLNSKMPTRFPPVVFYTPKE LGGLGMLSMGHVLIPQSDLRWSKQTDAGITHFRSGMSHDEDQLIPNLYRYIMPWESEFID SQRVWAEYALRTDMIQALGGVEGILEHTLFRGTYFPTWEGLFWEKASGFEESMKFKKLTN ASKDTMDGNTTQKFWLDIQLRWGDYDSHDVERYARAKFLDYTTDNMSIYPSPTGALIGID LAYNLHSAFGNWFPGCKPLIQQAMAKIMKANPALYVLRERVRKGLQLYSSEPTEPYLSSQ NYGELFSNQIIWFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSV WAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKG SELQLPFQACLKVEKFGDLILKAQEPQMVLFNLYDDWLKTISSYTAFSRLVLILRALHVN NDRTKMMLKPDKTTITEPHHIWPSLTDEEWVKVEVQLKDLILADYGKKNNVNVASLTQSE IRDIILGMEISAPSQQRQQIAEIEKQTKEQSAMTATTTKTVNKHGDEIIATTTSNYELNA FASKTEWRVRAISATNLHLRTNHIYVASDDIKEQGFTYILPKNVLKKFITISDLRAQIAG FLYGVSPPDNPQVKEIRCIVLPPQWGTHQAVHLPSTLPTHEYLSEMEPLGWMHTQPNELP QLSPQDVTTHAKIMDAHPTWDGEKTIAITCSFTPGSCSLTAYKLTPGGFEWGRNNSDKGN NPKGYSPSHYERVQMLLSDRFLGYFMVPAQGSWNYNFMGVRHDPSMKYELTLGNPKEFYH EVHRPSHFLNFSSIEEGQDREDVY--YTSTSTNINIGKHTKLICQGMTGKQGTFHTQQAL DYGSNVVGGVNVKKAGARHLGLPVFSNVSEAVAQTGADAXVIYVPPPVAAAAIMEAIEAE IGLVVCITEGIPQLDMVKVKAALMSQSKTRLIGPNCPGIIKPGECKIGIMPGHIHKQGCI GIVSRSGTLTYEAVHQTTETDLGQTLCVGIGGDPFNGTNFIDCLREFLKDDNTKGIVLIG EIGGTAEEDAAEFLKEHN--KNKPVVSFIAGISAPPGRRMGHAGAIIAGGKGGADGKISA LEAAGVTVTRSPAGIGSEL------------EILKCTICEEKLEDTHFVQCPSVTDHKFC FPCSRHSIRQQGAGTEVYCPSGKKCPLVGSNLPWAFMKGEIETILGXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKT CPLLLRVFWNMGSHHKLAQFARNKGPERELQIYTWMDASLKELTDLLREAVDEAKAKGTF IDFAIVYPDMRVPVYRSRDIGSTCVGKRGAEDGATLASVRFQIGDFIDIAITPP-GLGKT LQTVSLLAYMKHIRNIPSPHIVIAPKSTLNNWMKEIVRWTPSLRPVCVIGGKEERGXLFR DQLMGGEWDVCVTSYEMCYCERAVFKKFNWRYIVIDEAHRIKNEKSKLSEIVRTFKSTNR LLLTGTPLQNNLHELWALLNFLLPDVFNDSEDFDAWFDSDSCLNNNDLVSRLHCVLRPFL LRRIKKDVEKGLPPKIETKIYIGLSRVQREWYTKILMKDIDVVNGAGKTDKMRLLNILMQ LRKCTNHPYLFDGVEPGPPYTTDQHLVDSCGKMVLLDKLLPKLKEQDSRVLIFSQMTRVL DILEDYCMWRGFKHFRLDGQTAHEDRQQSIDAYNAPGSDVFIFLLSTRAGGLGINLATAD TVIIYDSDWNPQADLQAMDRAHRIGQKKQVNVYRLITENTVEERIVERAEMKLHLDNIVI QQGRLVDGNT-KDMLDMIRHGAQNVFASKDSAITDEDIDDILSRGKKKTAELNEKMSGLG ESSLRSLTLDTGGDSVYKFEGEDYRNKQKM-DMGMWIEPPKRERKANYAVDAYFREALRT SEPKAPRAPRPPKQPNVQDYQFYPPRLFELLDKEIYFYRKNIGYKVPKNHDLGSDADRVR REEQKKIDESDELTAKEQSEKEELLRGFTNWNKRDFNQFIKANEKYGRDDIDSICQDVEG KTPDEVMEYSSVFWERSTELQDIERIMAQIERGESKIQRRIGIKRALEAKMARYQAPFYQ LRIQYGTNKGKNYTEEEDRFLVCMLHKLGFDSENVYDVLRMQVRQAPQFRFDWFIKSRTA LELQRRCNTLITLIEKENSELEEREKAEKKK-----------------IPPISVVVDSAK GTKIITEHKYVDD-KLIKEISLYKIEKRRFSKSVAKRKTWRKFNAAANDGAGPNPSNTTE EVTMQFIQAKDMEAEDQVTKFKVLCRYCKGAHWSMECPHKDKLQAFKDSMPAGNKYIPPG MRAGADRKGESPYGDEFATVRVTNLPEDTQEKDL-------------------------- -------------------------------------MSESYDYLFKFLIIGSAGIGKSC ILHQFVENKFKQDSNHTIGVEFGSKVVNVGGKSVKMQIWDTAGQERFRSVTRSYYRGAAG ALLVYDITSRETYNALANWLTDARTLASPNIIIILAGNKKDLESEREVTFLEASRFAQEN DLIFVETSALTGENVEEAFLKCGRSILSKIESGDLDPERIGSGIQHGDATLRRL------ ---ILKPEKVPEMSTEDWPLLLKNFDKMMIRTGHYTPLPFGSTPTKRKLKDYIDAGWINL DKPSNPSSHEVVAWVKKILRVDKT--------------------------SQQSAGKEYM AVFQLHAAS-DETAVKQALEKLRGAVFQRPPLISAVKRQLRVRTQHEIKLLEMDDDKKRG IFWLSCE----------------------------------------------------- ------------------------------------------------------------ -----------AIALMTTADLMTCDHGCVAKLKRVIMERDTYPRKWGLGPVALKKKQMIL SGEIDKFGKP---------------------------------------------AKK-T SAAQLKSKQAVNTALRKGDNIETNKKFSAASNKQHSTNLNTLKLDNETDVLKHKTVTMDV SKVIIQARNAKSITQKELATKINEKPGVINEYETGKALPNNQILTKMERVLGVKLRGKEL GEPLAPK----QVLTEVLSQANCNGVTSTLLCNREGSLMAYSGNGKTDARVSAAISSNMW TTLERSASRSLSGDELDILIFNCETGRVAIGPCVNLLVCVYAESTVPMGMLRKKVQALIE YLESPLKEIL-----TAKVQIKKQTLQEAYDAPANFLEISVEEPESRNRYTDYAVKMKTN LPVFRLKESCVRRRYSDFLWLKSELERDSKIIVPAVPGKGLTRQLPFRSDDGIFEEEFIN ERKQGLEQFVNKVAGHPLAQNEVCLHMFLQDPTIDKNYIPGKIR--RKFSARLAEVGVLE TPKLHGKYDTGQLFLHKIFGYRGVILFPWVGKVFDRDVIGRSNRDVKGKSQTFYQVLLDS RDIPHIRVGTESVTFLSSQENGTLYSIPGLDYVDHHDVIPYTTTEKQPIENHLFDKFLQP EPPYVARESLREWQEANHPWLELTDVHRETTDQIRVTVMPFYIGDVQQSPVYWWRYCIRI ENLGQERIQLRERHWRIFSLSGTLETVRGRGVIGKEPVFTSSEPAFQYTSHVSLQAPSGH MWGTFQMEREDGTSFECRIPPFALESRPQ--MATSLGANTYNRQNWEDSEFPILCQTCLG DNPYLRMTKERHGKECKICTRPFTVFRWCPGARSRFKKTEVCQTCSKMKNICQTCLLDLE YGLPVQVRDHALKIAEEMPKSDVNKEFYIQNMDKEISNSDGTVAVGAVGKALKQNDMLLK LARTTPYYKRNRPHICSFWVKGECRRGEECPYRHEKPSDPDDPLSQQNIKDRYYGTDDPV ADKLLTRYASMPGPEPPSDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXX-----------------------------QEGQAELKSKWHPQQMIFPNSPGGIC YERQAHVPDKIYDSWHPLERAQYPKYFATRNQRKLEYIDRWQKKYG---IADYVKLEKIG EGTYGVVYKAKHRQKGNIVALKKIRLENEDEGVPSTAIREISVLRESRHPNVVTLEDVLI EENKLFLVFEFLSMDLKKYMDTLKNGR-MEPKLVQSYTYQLLVAIMFCHSRRILHRDLKP QNLLIDTKGTIKIADFGLARPFGIPVRMFTHEVVTLWYRAPEILLGAKRYSTDVDIWSVG CIFAEMCNNKPLFHGDSEIDQLFRIFRTLTTPNEENW----------------------- -----------------------------------RLFNTLGKVGIGLAVAGSVVNTALY NVDAGHRAVIFDRFSGVKTTPVGEGTHFVIPYVQRPIIFDVRTRPRSIPSVTGSKDMQVV NITIRVLFRPNCDTLPNIYTNLGIDYDERVLPSIVNEVLKSVVAQFDAGELITQREMVSQ RINDELFRRAESFGIMLDDISITHLTFGKEFTEAVELKQVAQQEAEKARYFVEMEEQRKL AAITRAEGDSIAADLLAQAFAKVGGGLVELRKLEAAEDIAYQMSQSPNVQYLPGSANLLL GL-MKTTEYSQTVKALPGTSFKIRGSKVEVTGKRGSLSRDLKHMRVEVLRVNKDTIQIRK WNATRRELA--------------------------------------------------- -------------------------------------------------NKDIRKFLDGI YVSEK------MGCATSADEKGAIERSKQIDKSLRWDGDKSSKEVKLLLLGAGESGKSTI VKQMKIIHERGYTPEECLKYRPVVYSNTIQSMIAIIRAMGNLGIDFAHPARAEDAVSVYS LSSAEGEGEMSPELAAVMKRCWADAGVQECFGRSREYQLNDSAEYYLNRLDRISQANYIP NEQDVLRTRVKTTGIVETHFTFKELNFRMFDVGGQRSERKKWIHCFEGVTAIIFIVAMNE YDLMLAEDQSMNRMNESMKLFDSICNNKWFVDTSIILFLNKKDLFEDKITKSPLS-CFPE YTGSNRPDEAAEYMEFQFYRRKDKKQVYSHFTCATDTRNVEFVMESVTNIIITMNLQ--- --RKFAVTKRLLNPKDSRIKENDRQF-KKKKDDPNVPKVREVTQASSALFFKYNTQLGPP FHVLMDTNFFNFSIKNKLDIYQSMMDCLYAKCIPYITDCVMGELERLGAKYTVAIKIAKD PRFVRLPCVHKGIYADDCLVNRITQHKCYIVATCDKDLKRRIRKVPGVPIMYVVNHRYSI ERMPDAFGAPR------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----KKGNYILSAGVDKTTIIWDAHTGDSTQQFAFHSAPALDVDWQTNTSFASCSTDQCI HVCRLGSEKPIKTFQGHTNEVNAIKWDPQGHLLASCSDDMTLKIWSMKQDNCVHNLQAHS KEIYTIKWSPTGPGTNNPNAPLI--------------------------------SVAFS PDGKYIASGSFDKCVHIWDIQTGSLVHSYKGTGGIFEVCWNHRGDKVGASASDGSVFVLD VRK--------------------------------------------------------- ------------------------------------------------------------ -----------------------------DWVMMQSCFNHHFMLVLEKQEKYDNLHLFYA IVLLIGTRKDAEMFAYRLELNCHRRRLTWEATPRSIHDGVQQAIVNSDCLVFESNIAQLF ADNGNLGINVTISMCMAYQTFQQEFMKTPPVTRAYTTACIVTTIAVQLDVVTPFQLYYHP ELIFRKAQFWRLVTNFLYFGGIGFGFLFNLIFTYRYCRMLEETSFRNRTADFIIMFLFGG SLMILSVHLVFLGQAFTMMLVYVWSRRNPFIRMNFFGIVNFQAPYLAWVFFAFSFLLGNS ITVDAIGIAVGHLYFFLEDIFPNQPNGFRILKTPALIERIFNSEPVDPNYEPLPPGGYDF G--LEFVSDAGYRLDGRKVNELRQVKAKVGVFTQADGSAYIEQGNTKVLAAVYGPREPRT QRNRHDKAYINCQYSMATFSTGLRKTRPRNDRRSLHMTQHLRNTFEATILVQLYPRSQID IFIEVLESDGGNYCASVNAATLALIDAGIPIKDYVCACSASLVGGASIVDTSNLEETGSP QVIVALLPKKDKMVFVEMNGRLHEDGLESLVDVAAAGCRDIYAIMENVVR-MTGRYYFVI VGHNDNPLFECDFS-TAKSKDP-KDDHKHLNQFIAHAALDMVDEHMWTSQNPYLRIVDKF NEWFVSAYVTPSQMRFLMLHDLKNEDGIKHFXTDIQDLFIKYTLNPFNKFNGPIKSTAFE AKCSNLGKRYL------------------------------------------------- ------------------------------------------------------------ ----------------------IGVCTHLGCAPIANAGDYGGYYCPCHGSHYDGSGRIRK GPAPLNLEVPEYSFPDEDTLVVGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXX------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------CGTPEYLAPEIILSKGYNKAVDWWALGVLIY EMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKSGVY DIKNHRWFSTTDWIAIYQKKVDAPFIPKVKGPGDTSNFEDYEEEVLRISNTEKCAREFAD FMLSDTILILCISVGTAFLGEGLTWLLVYRTETYKTLKYEVERQSKKIEKKKEIGGESSS RNAKKKLERQEEMLKNVNRNLSLAKMKSMFAIGFVFTALLSMFNSIFDGRVVAKLPFTPI GLIQNLSHRNLMGTDYTQCSFIFLYILCTMSIRQNIQKILGFAPSRAASKQGGGFFN--- ------------------------------------------------------------ -------------------------IWKKLIEKNVRTDSLWKGLSERRGWGKFIFKPRSI EFHKNHKFYQQLYPQIINDIERIESNWRNGEHSLQKIHCRSETSKGVYCLQYDDNRIVSG LRDNTIKIWDRNTLECVKILQGHTGSVLCLQYDDNIIISGSSDSTVRVWNINTFQMVNTL IHHCEAVLHLRFSDGIMVTCSKDRAIAVWDMQSASDITLRRVLVGHRAAVNVVDFDHRYI VSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYHDRLVVSGSSDNSIRLWDIECGSCL RVLEGHEELVRCIRFDSKRIVSGAYDGKIKVWDLQQALDPRAPTASLCIR---------- -------------------------MAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNS TFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKS FDNIQNWIRNIQQHASQDVEQMILGNKCDIEERRVISKSRGEQLAIEHKVKFMETSAKSA VNVEDAFFTLARDIKAKMDKKM---ETSADRNVEIWKIKKLIKSLEAARGNGTSMISLII PPKDQISRVSKMLADEFGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPGNGLVIYCGT IVTDEGKEKKVNIDFEPFRPINTSLYLCDNKFHTEALTALLADDNKFGFIIMDGNGSLFG TLSGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVSEMAVQLFITNDKV NCTGLVLAGSADFKTELSQSDMFDQRLQAKVLKLVDVSYGGENGFNQAIELASEVLANVK FIQEKKLIGRYFDEI--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------KSGHWLRIISGCLEVANSIVSLMEKSGKSVVVK-DEEHDMGT IVTCLAMLCMDPAYRTRRGFESLVQRIWVTLGHRFKDRLSLCADKPV----HPYFLVFLD CVWQMSEQFPYEFEFSGEYLCVLWDIALSGVTETFSCDSERDRRN--------------- ------------------------------------------------------------ ---------------------HNVFDIAWCQTAFPRLKKPHDDEELTKAIMEHVQRLSPN AMKLAPVADLEARIITVIEGQIILP-SIEGVVISEVQSIGEFKKNTCLARNIKAQIVVVL KTLPTVEAVHLIQRKVQQELSAKGSYK--FVLINE-GFVVEDAQATVDVLISTTRQNIQK LDGSLHLSAELMTRHLILIDETKWFEQASGHASVKVLIKVLMDLQHKFHGLRHLSPMMVD VLAHHSVIKG-CGEPLSVAPAFRRAFQLMASGIFLSTSVGPVDNIE--TFCDHHLLSPEA QDEVCCVAQTLLRVIGHGGFRKVINQDYSTDITMNMTKVGDVYVEPSVK----------- ------------------------------------------------AISSLQLPDQKL IDLYEQIVLELLELRELGAARSLLRQTDPMQQIKEQHPERYIHLENMLSRSYFDPREAYA DGQTKERRRAAIAQALSGEVNVVPPSRLLALLGQALKWQQHQGLLPPGTVIDVFRGRAAV SEQEEELFPTQMFKTIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFSTGKIRKDLK YQAQDSFMMMDQAVLSMCFSRDSEMLASAAQDGKIKVWRIATGQCLRRFERAHSKGVTCV NFSKDNSQLLSTSFDNIIRIHGLKSGKALKEFRGHTSFVNDAIFSFDSTKILSASSDGTV KVWNVKSTECVSTFKSLGGTGGSETTVHSIHILPKNIEQFVVCNRSNTVSIVNAQGQIVR SFSSGKREGGDFVCATISPRGEWIYCVAEDRVLYCFSTTTGKLERTLPVHDKEVIGITHH PHNNLLATYSEDGLLKMWKPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSI PKFYFKPPSDEEPLLQKLREDARTMFLQRKSKELLDSSELQNLLHLLDEHHTPPMEGDEQ MINFTDFLQVKKKASPNCRPFFTAKLFAKLMAGDAHGRICVTSFFNYIMRKVWLNQTRIG LSLYDVGGHGYLRESDLENYILELIPTLSQLDSLEKSFYSFYVCTAVRKFFFFLDPLRTG KIKIIDILSSGFLDDLLELRQEELSKSAQERNWFSATSSLRVYGQYLHLDKNRNGMLSKD ELAKYGTGTLTNVFLDCVFQECLTYEGEMDYKTYLDFVLGLENRKEPQAIQYLFRFLDIQ AKGYLNPFDLNFFFRSIQEQMRSHEQDPIPFNDVNDEIFDM------------------- ---------------------VEIVKGHLFEVGPRYTGLEYIGEGAYGMVVSATDRYNGS KVAIKKISPFEHQTYCQRTLREIKILTRFQHENIIYIQNLLGAENCTAMKDVYIVQCLME TDMYKLLKTQKLSNDHICYFIYQVLRGLKYIHSANVIHRDLKPSNLLLNTTCDLKICDFG LARVSDPHHDHTGYLTEYVATRWYRAPEVMLNSKGYNNAIDVWSVGCILAEMLSNRPLFP GKHYLDQLNLILQALGTPSIEDLNCIKNKKARGYLQSMPLHKKIPWENVADPKALDLLNE MLTFNPNKRMSVEQALAHVYLEQYYDPNDEPVAREPFTFATELDDLPKDKLRQLIYEET- -----ELTPPKTTPEWVKFCQKLFGGFSMLLWVGAVLCFIAYSIQASTSDDPAADNLYLG VVLTVVVVLTGCFSYYQEAKSSKIMESFKNLVPQYAQVVRNGSNLNIRAEDLVVGDVIMV KFGDRVPADIRVLNAQGFKVDNSSLTGESEXQSRKKECTSDNPLETKNLAFFSTNAVEGT CRGVVVNTGDRTVMGRIANLASGLEMSETPIAREIEHFIHLITGVAVFLGVSFFIIAFIL GYPWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTI CSDKTGTLTQNRMTVAHMWMDNHIIEADTSEDQSGAQYDKESSTWKDLARIASLCNRAEF RADQENVPILKRDTMGDASESALLKCVEMNMGSVEAVRQANPKVIEIPFNSTNKYQVSIH PDDDRFLLVMKGAPERILERSSTIIINGKEEELTNEWKEAFNQAYFELGGLGERVLGFCD YMLPADEYPKDYQFNEEEENFPLSGLRFVGLMSMIDPPRAAVPDAVNKCRSAGIKVIMVT GDHPITAKAIAKGVGIISEGNETVEDIAGRLNVPVSEVNPRDARACVIHGSDLRDMTPAQ IDECLRNHDEIVFARTSPQQ---------------AVTGDGVNDSPALKKADIGVAMGIS GSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLFFILCD CPLPLGTITILCIDLGTDMVPAISLAYERAESDIMKRKPRDPIKDKLVNDRLISMAYGQI GMIQASAGFFTYFVIMAENGFFPGRLFGIRSQWDSKAVNDLEDSYGQEWTYAQRKVLEYT CHTAFFVSIVVVQWADLMICKTRRNSIVHQGMLNHQMTFGLFFETTLAAFLSYVPGMDKL LKMYPLQWNWWIPAMPFSVAIFTYDEVRKYILRRNPGGFMERETYY-------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------EDYIFRLLTGYVDPPAGITVEGELAYNPYFPGGQISMPQQLYNDG VEYEDGTPATVSQMAKDVSVFLRWLSSREHDERKRIGLKVVLFMLTSLAYYWKRHIWSLH KTRVIA------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------EIWDACEGRLDMVVSGAGTGGTICGLARKLKEKNPMIKIVG VDPVGSLLAEPSESGFYEVEGIGYDFIPTVLDRSLIDRWYKSVDKESFLMARRLIGQEGL LCGGSSGSAMYCALQAVRDLGLGEGQRCVVILPDSIRNYMTKYLSDDWMMHRGF------ ----------FEGDRNDRSERHGFGKATLPNGDTYEGNYESGKRNGQGTYRMKNGARYIG EYIRNKKHGHGTFIYPDGSKYEGQWADDQRNGRGKYYYINGDTYEGEWRNHLRHGLGVYV SSESGSRYYGRWEGGKRSGHGQIIHANHRYIGKFVDDRPEGNGKFVFDIGCQQKGAYIMN DIIRLITKDLSEPYSIYTYRYFIHNWPELCFLAMDKNNCVGVIVCKLSWHKRM-RRGYIA MLAVEKEYRKLGIGSQLVQKSIGSMINKGCDEVVLETEITNKAALRLYEKMGFVRDKRLF RYYLDGVDAYRLKLWLKCIYSLMFHIPSNVQKCIKEEIHKDVLVSGDYEITDAPSEPVQL TVTDSKGHILYNKKEATKGKFAFTTEEMDIFSVCFQSKTQPGPLRNDREVFLDMKHGVEA KDYSNLAKAEQLKPLEVELKKLEDISEAIVADFAYMRTREEEMRDTNESTHTRVLYFSIF SMFCLL-XATWQVFYLRRFFKSKKLIDEMESGRTSSVGNDILGFFGEVVNKPDHGHLDWT KICANAAKVITFIDLAGHERYLKTTVFGMTGHAPDFSMLMIGSNAGIVGMTKEHLGLALA LSVPVFVVLTKIDMCPPNVLAETLRMLQKVLKSQGCRKIPVLVNNEDDVVVSAVNFTSER MCPIFQVSNVTGHNLNLLTKFLNLLSTRVRKDSPEFQIDDTFSVPGVGTVVSGTCLRGTI RLNESLVLGPDSIGKFSTAVVKSIHRKRLPVKQVRAGQTASFSLKKSGIRKGMVMVAPST NPQGCWEFEAEILVLHHATTIFCRYQAMVHVGSVRQTASIISMDRECLRTGDKARVHFRF IKNPEFLRLGTRLVFREGRTKAVGNVVHLLPHVPGNTRQQRIAKKA--QEKLAVVDDRRF HLFKVLRAHILPLTNVAFNKSGSRFITGSYDRSCRMWDTESGEELFSLEGHRNVVYAIAF NNPYGDKIATGSFDKTCKLWSAETGKCFHTYRGHTAEIVCVAFHPQSIVATGSMDMTAKL WDILATLSGHTAEVIALDFTTTGDRLLTGSFDHTVAIWDQRI------------------ ------------------------------------------------------------ --------EISKICFNPQGTRILTASSDKTARLWDPESGKCLQVLDGHTDEIFSCAFNYD GNIIITGSKDNTCRIWRGDVFLEKHWKSVIARSICDYFFEAQAKASNAEDISPIISTPHH YLINIYQRNIYFVAVVTTEVPPLFVIEFLHRVVDILDDYFTECSESAIKDNSVIVYEILD EMLDNGFPLATESNILKELIKPPNILRSITDTVTGKSTSMSATLPTGQLSNIPWRRTGVK YTNNESFIDLIEEIDAIVDKSGSLVFAEIQGHIDCAIRLSGMPDLTLSFMNARILDDVS- ------------------------------------------------------------ ------------------------------------------------------------ ------QSDSPVPDSNPTVSIQFCISQQLMSGLKVNRLDMYGEKYKPFKGVKYVTKSGKF QFRTMATYVKPAPRHATSDWYTSNYAVSTNAERQRGASNDVRQQSRYLRNETDNKTKWDQ HDNNTRLADRVDNIRLWKDILEDVLADLDKEIKDLSLSKDHLEEKLTAKNLATEVNVENL VMREGRQKIDLVEDEVEDELTKEKDVIAGVKRQLQQKIDESFEQLCKLQEARQQVLADLQ DKNVALGIDVDQYNLTEESSGISFKPDPLRVPKGSTTPQNWEDFSRYNRDRGLAEIEAAR RLREANAHTIQQTDNDLASQHAASDFAFRKRIHATKQALDELGWQKAQTEDEMAKLENEI RRLNDAIRAKINPQKLAETRLENRTYRPNVELCRDNAQYGLCDEVKQLEATSLALQEKLK QAQHALDGLEKQLHRINDDIATKTNSLKLDEQCMQSRGKL-------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------FAKKYAEGLKKADYWRAVFDDANLLIARLPTIAARIYNNVY ADGKQTSSIELNRDWSHNFCAMMNYSEHQFIELMRLYLTIHSDHEGGNVSAHTCHLVASA LSDPYLSYSAAMCGLAGPLHGLANQEVLNWLTSFRFTKEDVAKNIWNTLNNGQVVPGYGH AVLRKTDPRYACQREFALKHMPDDDMFKLVSTVYEVAPGILTEHGKTKNPWPNVDAHSGV LLQHYKMKEAEFYTVLFGVSRALGCMASLVWDRALGLPIERPKSITT------------- --------------------------------------TLSLNTAQTNEGVLFCKTHFNE AHLAKNSQI----------------PFDFTTENYKRADVLISNYPTGHQAAACLPLLDLA QTKXGYLSLSAMNRVAEVLKMPRMRVYEVATFYTMYNRVPIGKHHVQICTTTPCLLR--D STGILNAIRDNLGIQVGETTEDKLFTLTEVECLGACVNAPMVQINDDYYEDLQPEDMHEI LNDLKAGRVPKKGPRSG---RHSCEPLTGLTSLTEPPTGPGFGVRDDLMQKYEKLEKIGE GTYGTVFKAKNRESQEIVALKRVRLDDDDEGVPSSALREVCLLKELRHKNVVRLMDVLHS EKKLTLVFEYCDQDLKKYFDSCNREIDQTDVKSFMFQLLRGLDFCHSNNVLHRDLKPQNL LINKNGELKLADFGLARAFGIPVRFFSSEVVTLWYRPPDVLFGARLYTTSIDMWSAGCIF AELSNAGRPLFPGDNVDDQLKRIFKLLGTPTEKSWPGVSKLPEYKIMPNYPSSAAVVPKL NARGRDLLERLLVCNPANRMVADEAMAHPYFEE-------------------------KP LYDYLPAEYCSFHPAYDEFLSWIEETLNPALAKLVIKRQKRGGKGNMKIKKKESPQTVVI TRSSRGKRKYVTTIVGLATHDIEIKDAVKFLKGRLACGVSETADDEITIQGDVTESLFEI IPKQW-AIDEDHIEDRGDTK---------------------------------------- ------------------------------------------------------------ -------------------------------AESLQANDNIFVFLLSTRAGGLGINLTAA DTVIFYDSDWNPTVDQQAMDRAHRLGQTKQVTVYRLICKDSIEERILQRAKEKSEIQRMV IAGGNFRPDVLKPREVVSLLLDDDAMQKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXX--RFESALTPELKQELAKIANGVATPGKGILAADEST GTIGKRFSAIDVENNVDNRRKYRELLFTALADSISGVILFEETLYQETKEGVLFTKILKD QGIYCGIKVDKGVVPLAGTINEVTTQGLDGMAERCKQYKKDGCDFAKFRCVLKIQEWTPS NLAIVENANVLARYATICQQAGLVPVVEPEVLQDGAHDIVTCQKITEEVLSVVYRALKLH HVYLEGTLLKPNMVTPGQTCKARATPAEIAMATVTTLQRTVPPAVPGITFLSGGQSEEDA TVNLDAMNKKPWNISFSYGRALQASVLKAWAGKDDNVPAAQKELLKRAKANGDASLGKYE GGLQSAGAESLFVANHSY------------------------------------------ -------------------------------------------ENASGIPDFWLTIFKST ENLSEFVQEYDEPILRHLYDIKVIYGLSFTLKFLFTENEFFSNKELTKFYKMNNEVSDTN AFDYEGPEISECVGCDINWKNGKNVTVKTIKKKQENSRNASAKFITRQVENDSFFNYFKT P-VHDSDVPEEAEKLL-NDFELGHFLRDRVIPRAVLFFTGEEQEDEEEGDDEEDEIIFLK EGTDTSQGIPQLVSNINACQVVADAVRSTLGPLGRDKLIANAGSTCTISNDGATILNLLD IVHPAGRVLVEIAKSQDAEIGDGTTSVVLLASEFMTLLKPFAEEKMHPRIVIRALRKASS LAIERIKELEVTLKDENGVSDDMLRKCAATSLSSKLVSAHKDLFSDMVVKAVNTLDESLA VKDIGIKKVAGGALEDSQLVMGVAFKKTFSYAGFEMQPQXYTQPKIALLNIELELRAERD NAEIRVKDVTSYQQIVDAEWDILYSKMDKIVKSGAKIVLSRLPIGDVATQYFADRDVFCA GRVQEDDIQRTLKACGGALMSTVNDISLGTCAKFEEVQIGGERYNIFLDGKKAKTCTVII RGGAEQFMEETE------------------------------------------------ -----------------------TNILNILRQKHSGKWFGVDMETNGVADNFAKFVWEPS MMKVNAISAAAEAASLIFSIDETI--------------------KGNNIIPNVHCHKDWQ RHIKLWFNQPMKKMKRQQARKAK------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---MPNIKVFSGNSHQELGRSICDRLGIPMGRVTSRKFSNQETCVEIGESVRGEDVYILQ SGCGDVNDMLIELLIMINACKIASACRVTAVIPCFPYARQDKKDRSPISAKLVANMLSVA GADHIITMDLHASQIQGFFDIAVDNLYAEPAILKWIKENVPEWKNCVIVSPDAGGAKRVT SIADTLNVDFALIHKERKKANEVSSMVLVGDCTGRSAILVDDMADTCGTFCHAARKLIEA GATKVYAICTHGVLSGPAIQRICSSDFETVVVTNTIPQTENMKKCDKLSCIDVSMILAEA IRRTHNGESVSYLFSNVPL----------------------NIADVGGYVRLLEYNDIEG MILLSELSRRRIRSINKLIRVGRTECVVVLRVD-EKGYIDLSKRRVSPEEQQKCEEKFAR GKTVNSILRHVAELLKYDSDEQLEELYNKTAWYFERKKMD---AYSAFKLLVKQPELLDE CGLEEETKNLLLTDIKRRLTPKPVKIRADVEVSCYDYEGVDAVREALRAALVLSSENSPI KIQLIAPPLYVMTTQTLERSSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMVGTLTSDVRKEGVPVFPRGNCAACHQP IADKVITALGQTWHPQHFVCAHCKTPLGSSTFFERQGAPYCETDYHRLFAPKCAGCNGAI TNKCVTALDLSWHPEHFVCAKCGCSFDDNGFHEKNGRPYCRNDYLSEFAPKCGGCSRPII DDYVSALSKHWHNSCFACSECKIVLGGRSFFEHEGQPLCETHYHSRQGALCAGCSKPISG RCITAMYRKYHPEHFVCTFCRQQLNKGTFKEQADKPYCHGCFAKLFMRPLDEDETKLLFT KLSKYIGDNLKLLIDRSDGDYCFRLQNNRIYYIREDLMRKAGNISRDELISLGTCFGKIT KTKQFRLHITALDYLAPYAKFKVWLKTGAEQTYLYGNNVLKSGLGRISDDAPKHQGVVVY NMQDLPLGFGVTAKSTAECRNADPTAVVAFH-----------------RRFFVGGNWKMN GSKNAINGIIDNLKTSDDKTEVVVAPPACYLDFTKTALIQASAQNCHDVASGAFTGEISA DMVVDLGVKWVILGHSERRHVFGESDELIGRK----------------EKKEEREGGQTK VVNARQMAALDWSRVVIAYEPVWAIGTGLTASPEQAQEAHEDIRKWLESNVSKEVAASTR ILYG--------------------------------------DREGLLDPAWEKQQRKTF TAWCNSHLRKAGANIDNIEEDFRNGLKLMLLLEVISGEQLPKPDKGKMRFHKIANVNKAL QFIQGKGVKLVSIGAEEIVDGNVKMTLGMIWTIIVQNFHM-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------SWLLAELQRLERLHHLAMKFKHKCGIHEEWAVGKEDMLRAQDFQRLRLNDVK ALKKKHEAFESDLAAHQDRVEQIAAIAQELNTLDYHDSPAVNARCQAICDQWDSLGVLTA TRRAALEETEKILEAIDELHLDFAKRAAPFNNWMDGAKEDLVDMFIVHTTEEIQGLQEAH EMFKTTLGEAEKEFSVIMEL---------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------LVSLGCNIRDDKQGEADF QRIMTIVDPNRSGYVTFDAFLDFMTRESTDTDTAEQVMQSFKILAADQPFITADVLRREL PPDQAEYCIQRMSPYTGQGAPHGALDYTSFSTALYGESDL-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------KTIVWNGPPGVFELKSFQSGTEKMMEDVVKSTAAGAISIVGGGDTATCAKKFGT EDKLSHVSTGGGASLELLEGKALPGVAALSDA-------------VKLETSMGEITIELY WDHAPKTCQNFAELANKSYYDGIVFHRIIKNFMIQGGDPTGTGRGGSSIFGSTFEDEIHK DLKHTGAGILSMANSGPNTNGSQFFITLAATPWLDGKHTIFGRVESGMKVVQRMGLVGTD KDDRPVDVVKIV------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------FNLVKDSGTGLSRGYAFCEYVDQACAGLNGMTLG EKKLVVQRASVGAKGGVVPPVQLQIQGLEHADTPTEVLCLMNMVTTDDLVEDDEYDDIMD DIREECNRHGSVKSMEIPRPIKGVEVPGCGKIFVEFNTVLDCQRAQQALAGRKFSNRVVV TSFFNLDAYHRREFFAPLLDRVLVQRLAAEKVTAGGVVIPDSALSKMPQANVVAVGPGVT ID-GVQKPVSVAIGDKVLLPEYGGSKVTLQDEEYLLFRDSDILGKFT--KEKVPELQSNV ELIKFMKKKKDSFDVNFELSGNIYGDARVPSTSHIFLWLGASVMVEYELDEAEKMLNDNA AKRNLSQIEKDLDHLQDQITVTEVNLTRTHNWMVKNKK---------MESSGLFFDDLHK IRVLEPEVGQETSDLKDDCKDFLDRMEYFQKLAESFIGVIDDVAEKVEAEKIKAI----- ---VAKDRESQRQQLQSLIHVKRAQLERLRIHQKSLLKQEQEQKEVLEDL---------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------MDRSGFHMGATGRLQLMAKLAEGTGFQIPEQAAS LLQATQTAAPQVMATQCFMLTNMFDPSTAGNDWEQDIKDDVVEECNKHGGVLHIFVERNS ANGHVYVKCPSISSASASITALHGRYFAGKLITAAYVPLPDYHNLFPDSIRASAPLLP-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------VADALEPYQCEDGQEIVRQGEPGDEFYIILEGSAAVFQRRTENDESVEVG RLGPFDYFGEIALLLDRPRAATVIARGPLKCVKLDRSRFERVLGPCSDYLKRNIAQYNSF VSLSVSSYTGFPLSSRLLFIAERALADVRNNSNAELYKSIHMKLRDEVSSVLPAYEEEWY ESTQKKSAIQLDKLDSELKSSKSNSIKESIRRGYDDLADHHLMCGDLSNALKCYSRARDY CTNNKHVVQMFLNVIKVSVYLQNWAHVLNFKIKTEQAMESDQSEKDHLAISTRLNCAVGL SELATKKYRMAARSFLSANFDHFTCTDIMSPHDVLKYGVLCSLAYFDRQELKKNVISSSS FKLFLELDASIREMVFRFYDSKYAACLSLMNDIKDNLLIDIYLAPHVDHLYKQIRSKAIL QYFSPYNSANMIRMAESFNTTVSELEDELIVLILDGKINAYIDSHNKILYARNIDERSAT YEKALSMGLEYQRRVKALIVRAAISRNQLSVKSPSREGGEMS---------------NEF FDKFEDIADKILRKGKHILPHIARLCLIGTFLEDGLRMWFQWEDQRDYMESQWGCGYFLS VLFVLINLLGQIAGCAMILTRKQVPIACGILFGIVGLQTVAYSILWDLKFLLRNLALVGG VLFLLAESKSEGRSLFAGLPSVGENSPKQYLQLSGRLLLILMFLTLIRFDLNVVTVLNNL GGTALILLIAIGYKTKLASLLLVAWLTAVNFYWNAWWMVPAHRPMRDYLKYDFFQGMSVV GGLLMVVALGPGGYSMDEHKKKF------------------------------------- -----------------------------------IQSIPGLDCRKKNLDIIIIREQTEG EYSALEHESVPGVVECLKIITREKSMKVARFAFDYAVKHSRKKVTAVHKANIMKMGDGLF LECCAKV----------------------------------------------------- ----------------------------DQANPTAIMLCASNMLDHLGLDSHASMIRNAV TKVIKDGKVRTPDIGGYGTRTQFTTEIIKNI----------------------------- ------------------------------------------ELLAASYSGNSEAPHEPD GVVLLWNTAYGTQSPEYVLHYQPAVMSMCFSPFHASYVIGGTYSGQVVLWDIRTNKKTPV QRSMLSAAAHTFPVFSLAVVGTGNANSLISISNDGKLCSWSIDMLSKPQDSMNLAHK-TK VAVSCMSFVSGDVNNFVVGSEEGTAYTATRHGNNAGIGSIFEGHYGYATGIHCHPGRGQV DFSSYFLTSSFDYSIKLWNTKESRSRYSFETVSDYVMDVKWSPTHPAVFASAQCNGSVDL WNLNTDTEAPVVQARSAAFNQLAWSANGSQIAAGDQSGRIRLYDVADSERTPSAGEGLKL VNTLNELASNEV-----------------IEERLDQQINDLDNLDEDSIEAIRQRRLKQM QAAQKQKQQLLSLGHGVYSAVPDEKAFFEVTKQSNKVVCHFYRESTERCKIIDKHLNIIA PKYVGTRFIKVDVEKSHFLVEKLKIRILPTVALIKDSITVGYIKGFDELGGRDDFSTEML EWRLGVSEIIEYHGDLLTPPDER-------------KAVQLTAKGDVDKLKIVDLDEPKD DQVLVNVKAAGINFGELMIRMGVYDNPPSTPHQMGWEFSGIVEAIGKDVKIAKVGDRVAC VSGAWAEYCCKAFKIPESMSFEEAAAIPVVYLTAYIMLFDIGHLRPNQNVLIHMAAGGVG TAAIQLCKTVEGVQTFGTCSEKNEMVKNIGLDHPIDYRSKDFAAEVRRLAPEGMDIILDP LGGIDSQKNFKLLRPLGKLVHFGVASMVTGKKKSILTLAKTWWDSQSYKMLSLLGSNKGV CGFHMGRLDAMERILALAEEGKVAPVIDTKWALSEVGKAMTRMHERKNIGKLLLCPGL-- -------FLKKIIGSPVLVKLTGGIDYRGVLACLDGYMNIVMEQAEEYVNGQLSQKYGDV FIRGNNVLYISTVKRR---ANQSSLLLKRQLNDLMRNPVDGFSAGLVDD-DIHKWEVLII GPPDTLYEGGFFKAHLIFPPEYPNRPPKMTFKSDMWHPNVYASGEVCISILHEPGEDKYG YEKPEERWLPIHTVESILISVISMLASPNDESPANADAAIQWRDKKEEFKKRVTQCVRKS QDMTIRPKNDELKASLVDYGQYVSSILPKFVQKSQVSYGNELEICICPEGIIPVLSFLKN HHNGQYLCLADMGVVDVPTRPYRFELVYNLLSLRFNTRIRVKTYTDELTAVDSSFGVFKA VDWYEREAWDMFGVYFKGHPDLRRILTDYGFEGHPFRRDFPLSGFVELRYDEEQKRIVAE PLEMAQEFRKFDLSSPWEMFPDHGSALNPYCHVDFRAKVWTCCFCYQRNSFPQQYAGIDE QNQPAELIPQFSTIEYTINRGAVNPPIFLFVVDTCMEEEDLDALKESLQLSLSLLPPNAL VGFITFGRIVQVHELVHGAMPRSYAFRGNKDYTAKQVQSMLRLGRDMGHFSGNKFLQPVH KCDFYLNELLDSLQTDRWPVPQGRRPLRSTGAAISVAVSLMEVTYPNTGARIMLFIGGPC TQGPGTVVDDDLKNVIRSHNHIEKDTCKHMKKAIKHYESLANRATSNNHIVDVFSCALDQ TGLHEMKYLPNYTGGHMIMGDSYTTSLFKQSFKRVFDKSSQNEYNMAFAATLEVKTCREL KVMGCIGSCVSDNVGQYVAETELGVGGTSQWRMAGLYPTTTYGLYFEVVNPHNTPIPQGG RGYIQFITRYQHSSGVKKIRVTTLTRNWVDTTGGTANLEIGFDQEAATVLMARIALAKAE AQEGADVLRWLDRMLIKLCQKFGSFTKDVPSSFSLSELFSLYPQFMFHLRRSQYLQVFNN SPDETSYYRNKLMIENLTQSLIMIQPVLFSYSFNGPPEAVLLDSSNIKSDTILLMDCFFQ VLIYHGKTIDQWKKAGYQHQDDYATFKQLLEAPESDAQDILAQRFPVPRYIVTEDGGSQA RFLLSKVNPSNTHANADYDAGSQVLTDDVSLQVFLEHLKKLVVTNSAMANLSNEEQLRLI GELELEMMADMYNRMTSTCQKKCIPPKYNEKELSKGEAVCLDRCVAKYLDIHERLGKKLT SMTAADDPN------DSE----NKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYR KKVTLEGEETSVDILDDYAAIRDNYFRTGEGFLCLFSITEAESFQTTADFREQIIRVKNN EKLPFILVGNKADLGDKRKVTREEAQERADSWNVPYIETSAKTRMNVDKVFYDLLKMMKE NR---------------------------------------------------------- ------------------------------------RYPRIRDHLQKTLLDMVMRERKGE IVDRSSVKNACHMLMTLGIDKREVYEQDFETPFLKQSAEFYQVE---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------VIIKKRIEGLIDRDYLARSQKDRKSYEYVA-------------------- ---KGHSLLKKKSDALMIRFRNVLKKIIEAKTLMGEVMRVAAFSLAEAKYVSSSDLTNVL HNVTNATVKIRSKRDNVAGVVLHTYEHYSEGTDSFELTGLSRGGQQIEVLKKNYTKAIEL LVERASVQTSFVILDEAIKLTNRRVNAIEHVIIPKINKTISYIQSELDEMEREEFYRLKK VQDKKKEAK---------------VNVVVTGAAGQIAYSLLPLICKGEIFGEKQQVNLRL LDITPMLGALEGVVMELQDCSSPLLTACIATDDVERAFRDADAAFLVGAMPRREGMERKD LLKANVKIFEAHGKAIDNFAKKSIKVVVVGNPANTNALVASHFAPSIPKSSFTCLTRLDQ NRAQSMVASRNKVKNVIIWGNHSATQFPDVIHASAVYNAIKDDSWIKNEFIAAVQKRGAA VIQARKLSSAMSAAKAIADHMRDWWFGITEGEWVSMGVFSDGYGIDAGLMYSFPVKINGE YSIVQGLDVNDFARGKMDVTMKELQEEKESALTFCSNPSAVPMVGPNFKVGRKIGSGNFG ELKLGRNLYNNEYVAIKLEPMKSRAPQLHLEYRYYKQLGQAEGVPQVYYFGPCGKTNALV LELLGPTLEDLFDLCERKFSLKTVLMIAVQLITRMEYVHSKNLIYRDVKPENFLIGRPN- -KQNCIHIIDFGLAKEYVDADTKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEAL GHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRSTSIDVLCSGFPEELGAYLRYVRRLD FFETPDYAHLRKLFEDLMGKKGYSCDGDFDWSSRHLANAANNKVVNSTNGELAGTAGHSN TPITQAPEVEIVSETKCCMTTIRPFRCEDLLHFNEVNIDPLTETYGLSFYLQYMAHWPEL FLVAEDPSGNILGYIMGKTEGKNENWHGHVTAVSVASRFRRLHLAGEFMRRLEEFSERKQ CYFVDLFVRASNTVAVEMYEKLGYSIYRRVLNYYSAEDDEDAFDMRKALSRDVSKKSIIP LSHPVRPEDVDDQLTAALDLMRRMPPHATEHNLTNLIELVPSLCESLLSAIDQPLKIAIC NETGKEYLLCDYNRDSDSFRSPWNNQYDPPLPDGTVPSPKLRELEIKANEAFDQYREMYF EGGVSSVYLWDLDAGFAGVILIKKQGDKSGKCRGAWDSIHVVEVTEKSGGRIAKYQLTST VMLWLQTTKADSGTMNIAGSLMLQSSKDGPLDQG--HVSNIGQMVENHESQMRSKLDTIY FGKTKDYVNRMRSQVSLKRDKLRQDLARDLMNR--IDAGPDDVEDGFDAMSDGDTVDVLA ADGCVPAAERITTSYMTKYERARVLGTRALQIAMCAPVM-----------------EARK IPIIIRRYLPDRSYEDWRVDELIITDKSQTLKERLMAPSTGGAFTLGRGLAAGASAVGMG ALCYYGLGLSNKAGAIDKAIMWPEVVRDRIRSTYTYFGGGIAFTAIMRSPAMMNLMTRSS MLALFGTIAAMWGTGILCQSIPYPIDSKHMAWALHCGVIGAVIAPLTAFAGPLVVRAAAY T------LSTLAACAPSEKFLNIGGPLAMGFGVVFMSSIGSMFLPPTTAVGAGLYSVALY GGLVLFGAFMLYDTHKIIHRAENHPVMASQPYDPINNSVGIYLDTINIFVRLLTILSGGG GRKKMEIQYVYTKKRSEFGRQCNFSDRAAELHVDIAPDPSLAQNFIQRNPIDYGTQNVQE MSEHEVNTERFETESRGVNHTEGGWPKDINTQEVEQVMRYRKKVEKDQDYLNAIIDLSGI MNHCISQNNAIDIFETYFEEQHPEIVSAQLAPKTVGVIRDPNKIKRTASHISWYPDRGSK LAVAYYNQRFQSAAHGTMESYIWDIENSNAPETTFKPVSPIVCLEYNPKDSNVLCAGLYN GLVGVWDTRKHTPHSELSAVDHSHRDPAYTVTWVQSKTGTEFFSASTDGQVLWWDTRRLS EPTERLVVDLSKKQDISKALGTVCLEYESTMPTKFMLGTESGQIITCNRKGKTPADKIGS VYTSHVGPVYALQRNPTYPKYFLSIGDWSSRIWSEDIRESAILWMKPSSHYLLNGAW--- ------------------------------------------------------------ ------------------------------------------------------------ --------TKRIHKVIKKGVILGLKQVMKAVRDKKPGLVFIGGNVEPVDLFCHVPAVCEE KKVPYCYIPSK------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------EVRVLAYTQL LQSYRSLSLTYMADSFGVTVPFVDAELSRFIAAGRLHCKIDKVGGIVVTTRPDQRNEQYQ SVIKKGDLLLNRIQKLSRVIHL----------IAGIPYKDLSIGVLKETFQNENRVAIVP SVVTTLKKGFTVNIEENAGVNAKYLNKDFEAAGASIGSKDVFNSDIIFKIRPPSVDEITK FNEKSTLLSFVYPALNTELVDKMADRKLTSFAMDCVPRISRAQVFDALSSMSNISGYKAV VEAANNFGRFFTGQITAAGKVPPAKVLVIGGGVAGLSAMGTAKNMGAIVRGFDTRAAVKE QVKSMGAEFLEVSIQESGEGAGGYGKEMSKEFIEAEMALFAKQCKEVDIIITTALIPGRP APKLISKEMVESMKPGSVIVDLASEAGGNVETTRPGEIYTHAGVTHIGYTDLPSRLPTTS STLYAXNISKLFLSFGFNIDMNDEVVRGSIILKEGEKMWPPPVPAEPNYFTDTLKTSLLY TSGLGGMLGLGMASPNPAFTTMVTTFGLAGIVGYHTVWGVKPALHSPLMSATNAVSGITA AGGM-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------DMPVVITVLN SYSGWALCAEGFMMNNNLMTIVGALIGSSGAILSYIMCKAMNRSLPNVILGGYGTSSTVT GVAQKITGTHTEVNIDSTAEMIDEARNIMIVPGYGLCVAKAQYPIAELVSHLTEKGKNVR FAIHPVAGRMPGQLNVLLAEAGVSYDIVHEMDEINDDMPDIDLTLVIGANDTVNSAAEED PASIIAGMPVIRVWLSKQVVVMKRSLGVGYAAVDNPIFFKENTSMLLGDAKKTCDALLAK VR-----------------------------------------NKYSVKNNQGHQIYFAA EESNICHRTCCGPNRGFVMHITNHLDQEVLSVEREFKCLAGGCFLAGCTMELKIESN-GV VHGFFAQSLLKPCFVVLDSILRVEGPFCVCDGPLCAGDQVFQLLPTPIGHIKKVYSGFLR ELVSQADNFHIKFPQDLDVKVKA-------------------SVDKEMAEFVQKEQLKAT LQAAIGKIADTCWETCLEKPGTSLSSRNTTCVNNCTERF--------------------- -SSGLVQRRNVVTEDDEHDSKETRLTLMEEILLLGLKDKEGYTSFWNDCLSSGLRGCILI ELALKGRLELEKTGMRRRSLLNRKVLCRSATPTGDVLLDEALKHIKSTEPAETVQNWIEY LSGETWNPLKLRYQLKNVRERVAKNLVEKGVLTTERQNFVLFDMTTHPLTDDSFKKKLIK KVQDSVLSRWTNDIVRMDRRVLALIYMAHSSDVLENAFAPLSDDDYELAMKRVHELLDAE PDKESQKEGANELLWAAVSA-----------KKDCNVCYQTIDKLINSIPKVSEHLKKEC TGYTGKEEKICYYIGASSTSSTSILDKVADFVATGFPAEKICEKINKMDSQICELSYPAP INLD--NLDKMRVKELKKVLAQWGEECKGCME---------------------SAVLQGF HLNWMNLRDAETGKILWQGNEDLSVPGQEHEARVPKKILKCKSVSREINFSSAEQMEKFR LEQKVLFKGKCLEEWYFEFGFVIPGSTNTWQSVIEAAPENQMMPASVLNGNVVIETLFYD GGSLVSKSLVRVFYV--------------------------------------------- --------------------------------------ERQFRQKCIRCGLALYYRHRNL LTFILDGALKTDSDALKDVYKSIAAQQKVMVTKHTKNMGKFSSVTVSTVDEEDEELEAKA IADSYAANARMIEKQLQRRGFNKRRTEEEATTSDVKKRPKGTLID--------------- ----MSFTFGSPQKVDISQVDVPTLSGEFGILPNHVPTVAVLRPGIIKVYEKDGSINQIF ASSGAVTVNDDSSVQILAETACNVSDIDPNLVRQGSSEAQQALTTDKARAEAQIAVECYE AIAKCV-CKYFIAELESRLGESAGSKAILETGHGIDKRKRFEYLTSELRLTEALTDPHIC SRILEYNVHAERKGSLRYGKGRSETMSTLWDLRDKGVKVDLGMPYELWDHPSAEVSRMER ACYKLAEDFEEDIEEWYYRNQTSLKDFICRQRVLKNKNS--------------------- ------------------------------------------------------------ --SVGERGVIINTASVAAYEGQRGQAAYSASKGAIVGMTLPMARDLLSIGIRVNAIAPGL FSTPMLNQLPDKIRQFLADTVVFPKRLGHPAEYAHLVAAILQNPYINGETIRIDGGIRXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXMTATAQEEIINNTKTVVQGLDALRNEYSQILT NLYQSLKTIRIGSADVVEEKSSILRKSLEMIELGLNEAQVMMDMSSHLQFVEAEKQKLRA QVRRLCQENSWLRDELASTQQRLQESEQQVATLDEERNHLKFM----------------- ------------------------------------------------------------ ----------LAQILQKRGDMDKLKELLRGCVGLRQRTLGSNHSSVATALVNLAVIHSKN GEHFEAEPLYKQALAIYESCFGRNHPCVADTLRNLALLKYEQGDFEMAASLYKRGTEIRS S----------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------MDREGQSQSGYNKGA SQNIGGVRHAADIRADDMDRDGQGVVGGQYGTGGASQAGMSFGASRHAGDTKIAAADQAG QGIIGGQYGYTDGASQKGMSFGQGRKPADIDCGQMDKQGQSVVSSQISYVGGANQSGMSM GGRRDI------------------------------------------------------ ------------------------------------------------------------ --------PIVCHAWNNDSSKLAYPNDETILVSKKKYSEETKLIKHTSRVLGIDWAPQSN CIVTCGEDCNAYVWPTLVILRIKRAATCVKWSPKENKFAVGCGARQLCICYFDQAMDWWV AKAIKSDISSTITCVSWSPNNILVACGSTDFTVGVYSAYVKDIEEKPSGNAWGKKLSFQT LLRKINCQSGWVHSVCFSPSGNALAAVTHGSTITVFDSQLRTSHLPFLSCLWLSDSSFVA AGHDYKLILYKY------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------RLSVVDTPGFGDAV DNSNCWKPVIEFIEQQYDSYLNAESRVYRSAFSDTRVHCCLYFISPNGHGLKALDIEFMK HLHDKVNIIPVIAKADTLTTEECRDFKKQISNEIAQHKIRTYDFEEQEVRSHHRKLRQRI PFAVIGSNAIVNINGRKLRGRTYPWGTVEVENLAHNDFTALRDLLLRTHLQALKEQTNNV LYENYRQQKLSLVGQGPLMQMEEEKKDHSVKMKKMEADMEQVFELKVSEKQKKLKDFEAD LQKHEEQMRCNISQQQKDLEERKKQHERDKAQFEESMRMGNKYDSRTTTFSPEGRLYQVE YAINAVSHGGSCIAILGKDCVVMIVEIKNQEKLLDVEAVSEKIYRINRNNVCCVSGITSD ASVLINELRLIAQRHYLTYQSNIPCRQLVSSLSDIKQAYTQFGGKRPFGVSLMYAGWDEL NGLQLYCSDPSGNFNGWYAYCCGGEQQTGLGILNTDYKE-GMNRDEAMEFAVKVMLKIKE SD-LKPEQVEMAVVSADGDRIKLDMIKDDKIVDIIKIVQAKEKEAKEE---EINDGWTNL NRLKLQKEKTLKGASSIEMYQGLCDELKGWMQEKNAQVSNEDLGKDLRSVQALQRKHQNL EHELGPLSDKINKMNLLANAVRQSYPAETKHVNDREKEIMDMWKALQDKARDRKRKLGDA EQVQLFKEDAKELDIWINEVKAKLNERQLPTDVGDANSMIKDHHDLLDDINANLDKFEAV QDLGARILQSNP-KCEEVRSKMAQLAADQSAIGDLWRAKNDQLAAARELQLFLREADQID SATASHEAFLEFDDLGDTMDAVEALSKRHGDFEQTLSAQDERIRAMSDLADQLMRADHPD SKTIDDRRREVMARREGVKRRCSERRQQILASQALQEFKRDVDELNDWISEKYATATDES YRDPTNLLPKLKKHEAFEAELKANNDRVQWINEMGKALSADRHYASRDICSGLESLNERW KDLCARAEDKGVKLRQAAQQELLNKALKDAEAKLAEMENTLAADDIGTDLRTVKQLLGKH QILEHEMSANAENLKKIVDQGREMAQAGHFDSKSILKSVENFDQRFGALQGPMKRRREKL EASYKWHQYRFDADSELLWIKEHLLAATSPDLGKNLLEVENLIKNQQKFEIEVQGHIPIH EKLVGTGDALIKARHFAAEDIRQTNEELERCWKELTNASNNRRRRLLDNKEKQKYLLDAR EAEAWLHEQSTYLTSKDLGRDIAGTDKLIAKHKLFFADLESYGRVVTQLGQRAENLMKKE DNTGDDI-EECQASL-------------------VKLLSSTKELFKTRQHNLESGANARR IKAIKLGELLVSKKHEQAPAILKRTHGLVNEWNNLLKASADRGKGLEEAKDILAFNEEAD KINMWIREKEQIVSAGDTGRDYEHCLELQSRLEDAVNGVRVDDERIKSVNALADKLIKQG RTDVAAIEGIK-RNVNNKWERAKVSLEEHRARLAAALEIHTFDRDVDDVKERMADKAKTL SAGDLGADLRAVIALQRRQEAMEVDITAIHATLQGLERRTNELIVRYPKLANEIEQKQTE ALQSWEKLEDLAAERRIKLENSYKQQKFLSDTRQLMTWCQGVMQQMNADELAKDVPTAEA QVELHRERKMEIDARHETFEALQNAGQELSEDKAVRSALMTERTDALETTWAALMNAWEQ RRQLLMQCYDEQVYDDYVEQAEAWLATKEAFLAENLGNSRSVDELMTKHDNFMNTMDAQK EKIVTMEQLANALTQQQHYRVDYIKERCSSTWQRWERVNMMAVARKQKLADSKDFQQFLR NVNEVSTWVRQKLQIALDESYTEPTNIQGKILKHTAFEAELAANKRRLEAVTLEGEGMLS DNHYAKRE--IQSDLQQMARDWGKLEGASEIKRNRLNEAFKGLMFSRQCDDMATWMDDVE NQLSSEDHGKDVSTVTNLLKKHQTLEQDLINRQEKIEEIITIAKDFEKEEHFQSEAMLNR VTALQERFELLTEPCQIRRDNLEDALQLYHFYRDFQDQMSWIGEKIPAATSSDLGSSLHA AQSLHKKHIALEAEIVAREPLLEAVADRARRMVDGEHYAAEDIRCKLHEMTEALSDVKEK VAARKAKLLDSVDSQMFYAEVTEAETWIEDRKPMLTNLQLGTDEDMSQNLLKKLDVIDLD VDNFSNNIGELAALSRGLVERNHFDSENITQKQASIEKSYSGLQDLTHTRRKLLDYRLHA FVYLRETDDVLEWIAEKETIAASEDFGRDLESVQDLIVKHDAFEQDLAAIS-EQVESITK EAERLLVQFPEAQDHIHAKHEEMVHTWNELISCAAQRKERLAQAE--------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------IEDLGAVMEERLILDNRYTE HSTVGLAQQWDQLDQLGMRMQHNLEQQIQACSTSGVTEEQLREFSMMFKHYDRDRSGKLD TVSFKSCLRALGYDLPMVEEGETDREFEAILSIVDPNRDGFVSLQEYMSFLISRETENVQ SSQDVFKAFQALTSNEKPYITANELYANLSKEQASYCIRQMKGYVDQNGVAVPNAYDY-- --------AIQCYQCDSNEDTNCPSHKGFDEEINAVIDCSSMEAHTPGTFCMKVTQESPG WGGWKKITRRCGSRSDTGVAWGCRWDYGAKGVWKETCYCEDRDGCN-------------- -------------------------RGILVDWLVQVHIRFQLMPETLFLTTSIVDRFLQK PVSKKKLQLAGVTAMLLASKYEELYTPEISDFVYITDNAYSKEEIKKMEVEILRTITFDL GKPYAIHFLRRFSKAGQVSADIHVMAKYLIELPMASYAFAHILPSKLAAAALLISLKLHR WTSTLAFYSGYEEIELRPVVYNLCKLVKEKHQAIYSKYLSKKLMSISVSPYFNVPLMTTW AKSRKSRGRRNANPSPGLEMDLERVFIWDLDETIIIFHSLLTGMYAQRFGQDAPAAINLG LKMEEMIFGLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFHSAATNNLCL ATGVRGGVDWMRKLAFRYRRIKELYSSYRSNIGALLGPQKQEMWIQLRSE-EAFTDSWHT LAIKSLEAITSRSTCVNVLVTTTQLVPALSKVLLYGLGGVFNIENIYSATKIGKESCFER IVSRFGKGCTYVVVGDGRDEELASKQMNWPFWRITNHSDFMALHHALELDYLQPLLDVDG ERKHGNDVRKQNITACMAISNVVKSSLGPLGLDKMMVDDVGNLTVTNDGATILKQMEVAH PAAKILIELAELQDQEVGDGTTSVVILAAELLKNADELIRHKIHPTSIIAGYKLACKEAV NYIRNNLAISLDELSSESLINTAKTCMSSKVIYSDCELFASMAVKAVEAVKKTDSRGKTT YPITAINVLKAPGKSLRDSHLINGYAVNCVLAAQGMPKQLTDAKIAYLDFSLKKEKMKMG VQVLVDDPSKLQEIRQRESDMAMEKLDKILAAGANVLLLTGGMDDYLSKHCVNKGIMAVR RVLKRDLKRLVHATGGQVITSLANVEGDETFEASSLGKASSVCMEMYGENELVVIKGPAQ AGAAAIIIRGPNEYMMDEADRALHDALCVIKRVKESKSVVCGAGSVETALSIYLENFSTL VASREQLGIAEFAHALLCIPKQLAVNAACDAPELVSRLRAMHNEAQTKKDMNNLKWSGLD VVKKTIRNCRDAGVLEPSMVKVKALKFATEAAITILRIDDLVKLNPEK------------ ----EEKAILLVSKSILNNIIVQEKEVVIKYDIFNIGQSAAVNVKLEDTGFPEPDFEIVL GFPRVKWSRISPGQNVSHTLIVKPLEFGYFNFSSAEITYFATEETPQIGYSTAPGEGPIM KTNEFEKYYSTHYMDLAAFAAMCLPSLGIPFLLFWRSHSKYDSAKHAK------------ ------------------------------------------------------------ --------------------------------------------YSVDYKLDTYLKIAKL YMEDGSEVEAEAYVSRASLLQSETKDEKLKTSYMACYAQIQNFKRKFIEAAHKYTELSVS KEVAESERLVALNHAIICTILAPAGQQRSRMLAILFKDERCQQLPAFSILEKMHLGRIIR KDDL-------------------TVLDKLLTEH---------QNITFEELGRLLIISPHK AEKIASQMITEERMCGHIDQLTSLVQFEGTDALPAWDRQINSLCSQVNDVVEKISQLHPQ WFAE-------MKLTETAVQSFRVAKVFKENTQRISSINFSSTGENLISSSDDDSIIIYD CQSGTNKRSLNSKKYGVDHIHFTHAANSAIHSSTKVEDSIRYLSLHDNKYIRYYAGHTKR VVTLQMSPIDDTFISGSLDNTIRLWDLRSPNCQGLMNLPDRPVAAFDPEGLIFAAGIKSE MIKLFDLRSFDKGPFATFKMQSDPDHKWTGLKFSPDGKFMFISTDDDKIRLIDAFHGNPT ATFLGSPNPKKIPLEASFSPDSQYIFCGSVDGSIHCWNTATGKHTAILNCEHQGPIESVQ FNPKYMMLASACKQMSFWIPQVDDEYLITSRKGEKSNVMLIELNRPKALNALCDGLITEL NKTLNEYDQNDEIGCFVITGSKKAFAAGADIKEMVDVDSVTAYRTNMLGSWDQIRNIRKP VIAAVNGYALGGGCEYAMMCDIIYAGEKAKFGQPEVNLGTLPGCGGTQRLTKAIGKSGSM EMCLTSDMITAQEALTSGLVSKVFPEDQLVEEAIKTAEKIASXSKVAVQMIKEMINASYE LTLNEGLRSEKRMFCHSFAAKDKKIGMSAFLNKEKAVFED >Nephtys_caeca MTDRKAVIKNADMSEDMQQDAVDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSG------------------------------- -----GAGIGSVFGSLVIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLILFAFM SHYKESSKVPEAPIHRIRITLTSRNVKSLEKVCADLIRGAKDKNLKVKGPVRMPTKILRI TTRKTPCGEGSKTWDRYQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADMDQVM AFLEPAKTFSKDSIRLVKRCTKPDRKEFQKIAVATAIGFALMGFIGFFVKLIHIPINNII VMAQQVSKKRKFVADGVFRAELNEFFTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVL GEKGRRIRELTSVVQKRFSFPEGTVELYAEKVATRGLCAIAQAESLRYKLIGGLAVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPTNDYVDTAVRHVLLRQ GVLGIKVKIMLPWDPAGKIGPKRPLPDHIAIVEPKEEQLPTQPISEQKGGKMSKRGRGGS AGGKFRISLALPVGAVINCADNTGAKNLYIIAVHGIKGRLNRLPA--------------- ------------------------------------------------------------ ----------RKGKVQKVSLGPQVVDGEHVFGVAHIYASFNDTFVHITDLSGKETIVRVT GGMKVKADRDEASPYAAMLAAQDVAERCKVLGITALHIKLRATGGNKTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSNRRKG-------MGKPRGLRTARKLRNHRRDQKWHDKD YKKSHLGTRWKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP RDGCLNFIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALWKEKKERPRSEGI VTLRTRKFLTNRLLCRKQMVCDVLHPGRATVPKTEVREKLAKMYKTTPDVVFVFGFRTQF GGGKTTGFALIYDSLDFAKKFEPKYRLVRHGTRKQRK-------------------MPRV PLVSSKTYTTPRRPFEKERLDQELRLIGKYGLRNKREVWRVKYTLAKIRKAARELLTLDE KDQRRLFEGNALLRRLVRIGVLDESKMKLDYVLGLRLEDFLDRRLQTQVFKLGLAKSIHH ARILIRQRHIRVRKQVVNIPSYVVRLDSQKHIDFSLRSPYGGGRPGRVKRKNMKKGTGGG GAMGNIFQSLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIGEAREELMRMLAEDELRD AVLLVFANKQDLPNAMNAAEITDKLGLHSLRQRNWYIQATCATSGDGLYEGLDWLSNQLK NQKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXMVRMNVLADALRSICNAEKRGKRQVLIRPCSKV IIRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVHIQDLEKWTTNL LPSRQFGFLVLTTSGGIMDHEEARRKHLGGKMLGFFFMGRMHTPGKGISQSALPYRRSVP TWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKAKGLAAD IPEDLYHLIKKAVAIRKHLERNRKDKDSKFRLILIESRIHRLARYYKSTKVLPPVWRYES STASALVAEVQLAEIKLFGKWSSDDVQVNDISLTDYIPVKEKYAKYVPHSAGRYQVKRFR KAQCPIVERLTSSLMMHGRNNGKKLLAMRIVKHAFEIIYLLTGENPLQVVVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREASFRNIKTIAECLADELINAAK GSSNSFAIKKKDEFERVAKSNRMTEQMTLRGTLQGHGGWVTQIATTPQYPDMILSASRDK TLIMWKLTRDTNYGVPQRALRGHGHFVSDVVMSSDGQFALSGSWDGTLRLWDLSTGTTTR RFVGHTKDVLSVAFSADNRQIVSGSRDKSIKLWNTLGVCKYTIEDGHNDWVSCVRFSPNT QNPIIVSCGWDKLVKVWNLTNCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWD LNEGKHLYTLDGGDTINALTFSPNRYWLCAATGASIKIWDLEGKVVVDELRQEVISTSAE PPQCISLAWSADGQTLFAGYTDNLIRVWQVSMAARMREYKLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKVVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKLARQFNCAFLETSAKSK I----IFYDLVRQINKKNPESMSDDKKPGSEHINLKVTGQDGSVVHFKIKKNTPLRKLMS AYCERTGVKMEAMRFRFDGQPINETDTPSQLEMEDGDSIDVFQQQTGGMATLPMNPKPFL NGLTGKPVMVKLKWGMEYKGYLVSVDTYMNLQLANTEEYIDGCQTGNLGEVLIRCNNVLY IRGVEEEDEEGETKD-------------ATGGSMDINTALQEVLKTALIHDGLARGVREC AKALDKRQAHLCILANNCDEAMYVKLVEALCAQHGINLMKVDDNKKLGEWAGLCKIDKEG KARKVXGCSCVVVKDYGKDTQALDVLNEYFRSKRMAAIRKKLVIVGDGACGKTCLLIVFS KDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSI DSPDSLENIPEKWTPEVRHFCPNVPIILVGNKKDLRNDENTRRELAKMKQEPVKPEEGRA MAEKINAFGYLECSAKTKEGVREVFETATRAALQVKKKKKRGMDDFQSGEETAFVVDEVS NIIKESIEGAIGGNAYQHNKVNLWTSNVVEQCLNQLTKLGKPFKYIVTCVIMQKNGAGLH TASSCYWDNSTDGSCTVRWENKTMYCIVSVFGLAIMFSASAKIIKPAGETPDEFESSISQ ALLELEMNSDLKAQLRELYITAAKEIDVAGKKAIIIFVPVPQLRAYQKIQTRLVRELEKK FSGKHVVFIAQRRILPKPTRKTRRKNKQKRPRSRTLTAVHDAILDDLVFPAEIVGKRIRI KLDGSRLIKVHLDKNQQTTVEHKLETFSAVYKKLTGKDVSYEF----------------- ----------GKD-DKEWIPFTKLGRLVKDTKIKTLEDIYLFSLPIKEFEIIDYFLGTAL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDFNGHIGLGVKCSKEVATAIRGAIILAKLSV IPVRRGYWGNKIGKPHTVPCKVTGKCGSVVVRLIPAPRGTGIVSAPVPKKLLTMAGIDDC YTSARGQT---------------------------------------------MSGGLDV LGLKEDDVTKLLACSTHLGATNVDFQMEQYVFKRKPDGVHIINLRKTWEKLLLAARAIAA IENPAEVCVISARPYGQRAVLKFASATGATPVAGRFTPGTFTNQIQAAFREPRLLVVTDP RTDHQPVREASYVNIPVIALCNTDSPLRYVDVSIPCNNKGVHSIGLMWWLLAREVLRLR- ------------------------------------------------------------ -------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXAPASSTSVGGTVRQRKTVTNGAGAAGMWRFYTEDSPG IKVGPVPVLVMSLLFIASVFMLHIWGKYTR-KKESRKKSSINDVVTREYTVNVHKRIHGI GFKRRAPRAIKEIKKFAEKMMGTPDVRVDTRLNKHVWSKGVRNVPYRVRVRLARKRNEDE DSPHKLYTLVTYVPVTTFKGTQTVNVDSTSKSEFLVNGKYRLVRKIGSGSFGDIYLGINI SNGEEVAVKLESHKARHPQLLYESKLYKILQGGVGIPHIRWYGEKDYNVLVMDLLGPSLE DLFNFCSRRFTMKTVLMLADQMIGRIEYVHNKNFIHRDIKPDNFLMGIGRHCNKVFLIDF GLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRGS LPWQGLKAATKKQKYEKISEKKMSTPVEILCKGYPAEFAMYLNYCRGLRFEEAPDYMYLR QLFRILFRTLNHQYDYVFDWTILKQRAATSMNAEKLKQRIGGKGTARRKKKVVHRTATTD DKKLQSSLKKLAVSNIPGIEEVNMIKEDGQVIHFNNPKVQASIAANTFAITGHAETKQIT EMLPGILNQLGAESLANLKKLATETADIDDDDDEVPDLVENFDEASKGEMTRYSLDPENA TKSAKACGSHLRVHFKNTRESAHNIKHMHLRRAVKYLKAVINKTECVPFRRYNGGVGRCA QAKHWGATQGRWPKKSAEFLLQ-LKNAESNAEYKGLDTDQLVIDHIQVNRAPKMRRRTYR AHGRINPYMSSPCHIEVILSEREQVVSKP-------------------KKTGPKPELTEE QKQEIRDAFDLFDTDGTGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGTIDFND FLTMMTQKMSEKDSKEEILKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQEADRD GDGEINEQEFLRIMKKTSLYMGISRDKWHKRRATGGRQNPIRKKRKFELGRPAAHTKIGP KRIHTVRTRGGNKKYRALRLDTGNFAWGSEAQTRRTRIIDVVYNASNNELVRTKTLVKNA IVQVDATPYRQWYEGHYALPLGRKKGVKLSETEEAVLNKRSKKTQKKYDERKK------- -----------------------------------------------MSLVIPEKFQHIL RVMNTNIDGRRKIAFAMTAIKGIGRRFSHVVCKKADVDMTKRAGELSEEEVEKIITIVSN PRQYKIPDWFLNRQKDVKDGKFSQVMANILENKLREDLERLKKIRAHRGLRHYWGLRVRG QHTKTTGRRGRTVGVSKKKGSGTESDSDDSAPELEDLAQAAGLPEELVSKAKQSRSEKKA RKAMSKLGLKQVAGVSRVTIRKSKNILFVINRPDVYKSPASDTYIVFGEAKIEDLSQQAT VRAVDQFKTEEEVDEAGVEAKDIELVMSQANVSRGKAVKALKNNQNDIVNAIMMGRVRTK TVKKAARVIIEKYYTRLTLDFHTN------------------------------------ -------------------------------------------------------MRWEY KEEHPFEKRRAEGEKIRKKYPERVPVIVEKAPKARVGDLDKKKYLVPSDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGALYQEHHDEDFFLYIAYSDESVYG-RDLHIMKL CLNICVGESGDRLTRASKVLEQLTGQTPVTSKARYTVRSFGIKRNEKIAVHCTVRGAKAE EILERGLKVREYELRRNNFSGTGNFGFGIQEHIDLGIKYDPGIGIYGMDFYVVLGRPGFN INKRKRRVAKIGFKHRIVKEDAMKWFQQKYDGVILPGKMGIKFLEFVKPFCAVLPEIAKP ERKIQFREKVLWTAITLFLFLVCCQIPLFGIMSSDSADPFYWMRVIMASNRGTLMELGIS PIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMVITVGQAIVYVMTGMYGDPAE IGAGVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVN TGRGTEFEGAIIALFHLLATRSDKVRGLREAFYRQNLPNLMNLLATVLVFAIVIYFQGFR VDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAAKFSGNFFINLLG VWADVGGGGPARSYPIGGLCYYLSPPETLSHVFDDPVHAVLYIIFMLGSCAFFSKTWIEV SG-XAKDVAKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIG SGTGILLAVTIIYQYFEIFVKEQSE--GMSTLLFQSERAFQKQPTVFLNKKRVVTQRHYK SIGLGFKTPREAIDGHYIDKKCPFTGNVSIRGRILTGVVLKTKMERTIVIRRDYLHYIRK YNRFEKRHTNMSVHLSPAFRDVGTGDVVTVGECRPLSKTVRFNVIKVAKGSGSRKGFQKF MVNVPKTRKTFCKGKKCRKHTLHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFHK KAKTTKKITLKM----------------------------------MGRVIRSQRKGAGS VFKAHTKHRKGAARLRPVDYAERHGYIKGVIKDIIHDPGRGAPLAKVMFRDPYRYKMKLE TFIAAEGMYTGQFVYCGKKANLQIGNILPVGSMPEGTIVCCMEEKAGDRGRIARVSGNYA TVVAHNPDTKKTRVKLPSGSKKIIPSTNRAMVGIVAGGGRIDKPMLKAGRAYHKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGKASTVRRDASAGKKVGLIAARRTGRLRGTKQIVV KAKRTKKVGIVGKYGTRYGASLRKLIKKMEVTQHGKYTCSFCGKESMRRKAAGIWNCKSC LKTVAGGAYVYSTTAAATVRSGVRRLREMKEMGRRPARCYRYCKNKPYPKSRFCRGVPDP KIRIYDLGRKKARVDDFPLCVHLVSDEYEQLSSEALEAARICANKYLVKFCGKESFHLRM RAHPFHVLRINKMLSCAGADRLQTGMRGAFGKPQGTVARVNIGQPLMSVRARDQHKEQVV ESLRRAKFKFPGRQKIFTSRKWGFTKWNRDVYEDMRQDGRLKPDGVNVKYYPNHGPLKAW KALQKVTKVLGRTGSQGQCTQVRVEFLDDSNRSIIRNVKGPVREGDILTLLESEREARRL RXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-VDDRAAAKELDQWIEQLNECKQLSENQVK TLCEKAKEILTKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDR GYYSVETVSLLVALKVRFKDRITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDRQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHSNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRC GNQAAIMELDDALKYSFLQFDPAPRRGEPHVTRRTPDYFLMGAYKYMQELYRKKQCDVLR FLLRVRSWQYRQLSTIHRASRPTRPDKARRLGYRAKQGYCIYRIRIRRGGRKRPVPKGAT YGKPTNQGVNSLKNQRSHQAIAEERVGRRCGGLRILSSYWVSQDSSYKFYEVVCVDPNHK GIRRDAKINWIVNPVHKHREMRGLTSSNRKSRGLGKGHKFNQTIGGSRHANWKKHNRLSI RRKRGIAVGRLTEERKAWRKDHPFGFVARPTKNPDGTLNLMNWECAIPGKKSTPWEGGLY KLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSLLDEEKDWRPAVTIKQILLGIQE LLNEPNIKDPAQAEAYTIYCQNKVEYERRVREQAMKFRDPSLGKSSKMLQHINFRMRCTL QDGRIFIGTFKAFDKHMNLILGDCDEFRKIKPKKSKEREEKRVLGLVLLRGENLVSMTVE GPPPAEEGIARVPLPGAAGGPGMGRAAGRGVPSQGGLQGPVRGVGGPSQQIMQPQPRM-- GGPPQDVAIFKLVLVGDGGVGKTTFVKRHLTGEFEKKYVATLGVEVHPLPFHTNRGVIRF NVWDTAGQEKFGGLRDGYYIQGQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCG NKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLVGDPNLELVAMPA IAPPEVHMDPNLAKQYEQELELAQQTALPDEDDELTEGIRPYYISKIEELQLEVSEKTQN LRRLEAQRNELNSKVRMLREELQLLQEQGSYVGEVVKPMDKKKVLVKVHPEGKFVVDLDK NIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEI KEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ KFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRLESGSGGDSEVQRTMLELLNQLD GFEPHQNIKVIMATNRIDILDSALLRPGRIDRKIEFPAPNEDARLDILKIHSRKMNLTRG INLRKIAEMMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFELAVAKVMQKDSEKNMSI KKLWKLGFAENFMLSGVAAAVSKTAAAPIERVKLLVQNQDEMLKSGRLDKPYKGVIDCTM RVLKTEGVLPFWRGNLANCIRYFPTQALNFAFKDQIKAMFKMQKTDPHAVKF-------- ------------------------------------------------------------ ------------------------------------------------------------ -AVKYKGSMDCAVQIVKSEGFMSMMKGAGANILRGVAGAGVLAGFDAFKGLYIQWRLMTD CSDLDRQIEQLRRCEIIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLK ELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQV YGFYDECLRKYGSITVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRSIDRK QEVPHDGPMCDLLWSDPDETQG--------------------------KLICRAHQLVHE GYKYMFDEKLVTVWSAPNYCYRCGNIAAVLAFSDSDHKEAKLFRAVPDSER--------- VRLPPEVNRILYVRNLPYKITAEEMYDIFGKYGAIRQIRVGNTPETRGTAFVVYEDIFDA KNACDHLSGFNVCNRYLVVLYYQSNKAFKKIDTQKKKDEIDKMKTKYGLSTPEI-MSIGV PIKVLHEAEGHIVTCETKTGEVYRGKLIEAEDNMNCQMANITVTYRDGRVAQLEAVFIRG SKIRFLILPDMLKNAPMFKKVGAGRGKSAILRAAARGRGRASGG-----MQNDAGEFVDM YIPRKCSASNRIIHAKDHASIQINLAEVDDSTGRMTGQYKTYAICGAIRRMGESDDCLIR LAKRDGIVAK--------------------------------------------MIFLRN RLKYALTYDECKKILNQRLVKVDGKVRTDNTYPAGFMDVVTIEKTAENFRLIYDVKGRFI VHRITAEEAKYKLCKVRRVQVGPKGVPFLTTHDGRTIRYPDPLVKVNDTVQVMGTKDDEY DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTA GQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADNNIVIMLVGNKSDL RHLRAVPTDEAKAFAEKNNLSFIETSALDSTNVEAAFQNILTEIYRIVSQKQIRDSPDDG PVTTIKVAPTDNPAERKRPCCSMSARYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVR GKDIVVLGVEKKAVAKLQEDRTVRKIALLDDHVAMAFAGLTADARILINRARVECQSHKL TVEDPVSLEYITRHIAQLKQRYTQSNGRRPFGLSALIVGFDGTPKLYQTDPSGTYHEWKA NAIGRSAKTVREFLEKHYNDEVASEKETIKLALKALLEVVQSGSKNMEIAIMKNQQPLQM MDNDEIEKYIQEIEKEKEEEAEKKKQKGGGSGGDKKDDKDRKKKYEPPVPTRVGKKKRKM KGPEAANKLPQVTPYTRCRLKLLKLERIKDFLLMEEEFIKNQERLKPQEEKHEEERSKVD DLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDALEPGCSVLLNHKVHAVV GVLGDDTDPMVTVMKLDKAPQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIRPPK GVILYGAPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPS IVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPA LIRPGRIDRKIEFPLPDEKTKRRIFNIHTSRMTLADDVSIDDYVMAKDDLSGADIKAICT EAGLLALRERRMKVTNEDFKKAKENVLYRKNEGTPEGLYLKRKPYSPFQGKSNVDYAIAR VDDLVNWARKSSLWPLTFGLACCAVEMMHFAAPRYDMDRFGVVFRASPRQADCIIVAGTL TNKMAPALRKVYDQMPEPRYVISMGSCANGGGYYHYSYSVVRGCDRIIPVDIYVPGCPPT AEALLYSVLQLQRKIKREKRAQMWYRK--------------------------------- -NSNYKNDTMIRKEAYVHKSVMEELKRVIEDSEVMQEDDNLWPPPDRVGRQELEIVIGDE HISFTTSKIGSLLDVNQSKDPEGLRTFYYLVQDLKCLVFSLIGLHFKIKPIMVAQKKVKK AIESINSRLALVMKSGKYVLGYKQTLKTLRMGKAKLVIIANNTPPLRKSEIEYYAMLAKT GVHHYNGNNIELGTACGKYFRVTTLSITDPGDSDIIRSMPAGMTEYKLVVVGAGGVGKSA LTIQLIQNHFVEEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGF LCVFAVNNTKSFEDINQYREQIKRVKDADEVPMVLVGNKVDLPTRTVETKQGRALADSYG IPYIETSAKTRQGVDDAFYTLVREIRKYMSDRYNIHSQLEHLQSKYIGTGHADTSKWEWL TNQHRDSYASYMGHFDMLNYFCLVENEARARVRFNLMEKMLQPCGPPPERPEDMKVELCS FSGFKIYPGHGKRVVKADGRAFQFLNGKCEKSHAMKRNPRKINWTVLYRRKHKKGQQEEV SKKRTRRTTKFQRAITGATLADIMAKRNQKPEVRKAQREQAIRAYKEKQKQKETSKPRVG GKRMKLNISYPATGCQKLVEVDDERKLRAFYDKRMSAETSAECLGDEWKGYVVRISGGND KQGFPMKQGVLTTGRVRLLLSKGHSCYRPRRSGERRRKSVRGCIVDANLSVLNLVIIKKG EQEIPGLTDSTVPRRLGPKRASGIRKLFNLGKDDDVRQYVVRRPLPAISKAPKIQRLVTP NVLQRKRHRLALKRRRASKKREDAADYAKLLAQRMKEAKERKMERRRSASQSKXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGKSKGPKVTDKV FFDISIGGEAAGRIVIGLFGKTVPKTVENFKTLAEGTKTYKDSKFHRVIKDFMLQGGDFT RGDGTGGKSIYFPDENFKLKHYGAGWLSMANAGKDTNGSQFFITVKKTDWLDGRHVVFGK VLEGMDVVRKVEATKTDRDKPEKDVVITDSGSLPVDKPFAVTKDDAK-KKKKLLLKFTVD CTHPVEDGIMDCANFEKFLHERIKVQGKTNNLKSKVVVSSDIPFSKRYLKYLTKKYLKKN SLRDWLRVVASTKDAYELRYFQINNEEEDEEGD-NKEEKGEDEKVYGGCEGPEAMYVKLV SSDGHEFIVKREHALTSGTIKAMLSGPGQFAENETNEINFREIPSHVLQKVCMYFTYKVR YTNSSTEIPEFPISPEIALELLMAANFLDCTRIITLDELKAHKDSKSCWIAIHDKVYDVS KFLDEHPGGEEVLLEQAGSYATESFEDVGHSTDAREMMKQYEIGELAEDARSSPMSWIIP LGIAIVAALVYRFV---------------------------------------------- -------------------------MYELYDPCTVMFFYRNKHIMIDLGTGNNNKINWSM EDEQEFIDIVETVFRGARKGRGLVVSPKDYSTKYRYKKLKRQLEFLQVQEEYIKDEQRNL KKEYLHAQEEVKRIQSVPLVIGQFLEAVDQNTGIVGSTTGSNYYVRILSTIDRELLKPSS SVALHKHSNALVDVLPPEADSSITMLSADEKPDVAYSDIGGMDIQKQEVREAVELPLTHF ELYKQIGIDPPRGVLMFGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVR DVFRLAKENSPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTVNVKVI MATNRADTLDPALLRPGRLDRKIEFPMPDRRQKRLIFATITGKMNLSDEVDLEDYVARPD KISGADINAICQEAGMQAVRENRYVVLAKDFEKGYKNNIKKDETEHEFYKAHAPLSLDSV RERVLLVLKLYDKISPEKLTLDSNFMNDLGLDSLDHVEVIMAMEDEFGFEIPDSDAERLL RPADIVQYIADKEDVGRRVQTIPDDLRNVEFETSEEVEVTPTFDAMGLREDLLRGIYAYG FEKPSAIQQRSIKPIVKGRDVIAQAQSGTGKTATFCTSILQCLDTQTRETQALVLSPTRE LAVQIQKVLLALGDYMSIQCHACIGGTNIGEDIRKLDYGQHVISGTPGRVFDMIRRRNLR TRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVCLISATLPHEILEMTSKFMTDPI RILVKRDELTLEGIKQFFVAVEKEEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKM REANFTVSSMHGDMPQKERDEIMKEFRSGASRVLITTDVWARGLDVQQVSLVINYDLPNN RELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLIMAMRRP FDPVAHELDAGFRLTKFADLKGGCKVPQEVLLKLLEGLNQPDGSEQSHFQYVAPVPRIGI GMDSCVTPLRHGGLSLVQTTDFFYPLVDDPYMMGKIACANVISDLYAMGVTECDNMLMLL GIPQKMTEKERDVVIPLLLRGFKDLAEEAGTSVNGGQSVLNPWMTVGGVATTVCQPNEFI MPDNAVVGDVLVMTKPLGTQVAVNAYQWLDQPDRWNRIKLVVSEDDVRKAYQRAMFSMAR LNRTAARLMHKYNAHGATDITGFGLLGHANNLARIQKNEVGFVIHNLPVIAKMAAVSKAC GNMFGLMQGNSAETSGGLLIALPREQAAAFCKDIEKQEGYQAWIVGIVEKGNRSARIIDK PRVIEVPAKEKDFLTTLFRSTDGFFINIDAHAEECFFDKVSSGTKMSLMFEVAEGGFLDI DVRITGPDGKNIYSGERESNGKYTFAAHMDGIYKYCFSNKMSTMTPKIIMFSMDIGEKPK TNHNKLEEMINELSTSLTGVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMT LGQIYYLKRFFEVRRVVMAATLRPYLNAVRHTLTAAMCLENFSSQVVERHNKPEVEVRTS KELLLTPVVISRNEKERVLIEGSVNSLRISIAVKQADEIEKILCHKFMRFMMMRAENFIV LRRKPIEGYDISFLITNFHTEAMYKHKLVDFIIHFMEEIDKEISEMKLAVNSRARISAEE FLKRFSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLV TMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTMPNTFKTLDSWRDEFLIQAAPRDPEN FPFVVIGNKIDLENRAVPSKRAQAWCHSKGDIPYFETSAKEAINVEQAFQTVAKNALAQE TNVELYNEFPDQIKLTNDQNKEGCGCTAAFDARFPNQNQTRNCWQNFVDYHRCHKIDDYE PCEYFKRVYKSLCPNEWSSRWQEQVEAGNFAGKI-KDFLGKDQRKVKDDEKTDEPIRALD EGDIALLKSYGAGMYSRPIKSTEEDIQNVLKRVNELSGIKESDTGLAPPALWDLAADKQT LQSEQPLQVARCTKIINADSEDPKYIINVKQFAKFVVDLGDQVAPTDIEEGMRVGVDRNK YQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIDKLREVVETPLLHPEKFVNLGI EPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMART KKACIIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDT LDPALMRPGRLDRKVEFGLPDLEGRSHIFKIHARSMSVEKDIRYELLARLCPNSTGAEIR SVCTEAGMFAIRARRKMATEKDFLEAVNKVIKAYAKFSATPRYMTYNXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXELEQLRQEAEQLKNQIREARKAAADTTLSQAATCVEPVGRIQMRT RRTLRGHLAKIYAMHWASDSGNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAP SGNYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDNQIVTSSGDMTCA LWDIETGQQTTSFTGHTGDVMSLSLSPDMKTFVSGACDASAKLWDIRDGMCKQTFSGHES DINAITYFPNGFAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLG GYDDFNCNVWDTLKQDRAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKIWNMSYAYLF KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES FRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLEARR DVKKEEGEAFAREHGLIFMETSAKTAANVEEAFINTAKEIYQKIQDGVFDINNEANGIKI GPQHSPTSPSSGGGAKPGGSMTRGRTELGDVTVHNIKQLKRLNQVVFPVTYNDKFYKDVL EVGELAKLAYFNDIVVGAVCCREDKSDGQRRLYIMTLGALAPYRRLGIGTVMAKHVLKIC EEDGNYDNVFLHVQVNNEGAIRFYEKFGFEIVELKQNYYKRIEPADAYVLQKTFRKMPKQ IMEIKDFLLTARRKDAKSVKIKKNVKFKVRCSRYLYTLVIQDREKAEKLKQSLPPGLAVK ELKMSKISREHVAECIREMLSKKRKFTETVELQIALKNYDPQKDKRFSGTVKLRHIPRPK LKVCVLGDQQHCDEAKANEVACMDVEALKKLNKNKKLVKKLAKKYDAFLASDSVIKQIPR ILGPGLNKAGKFPSTLTHSESMMGKVDEVKATIKFQMKKVLCLAVAVGHVNMTPEELQSN ITLAINFLVSLLKKNWQNVRALYIKSTMGPAQRIYMADADKLNIDSIIARLLEVRGSRPG KNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLTAGRPVTPPRGTAKNK GKMMFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEIVGTNVSTT YITCPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPF ICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDEL PAEFKLYLPIQ--MTDTKIQNFQDPFAEDHDIHIRIQQRNGRKTLTTVQGINPEYDLKKI VKACKKDFACNGTVVEHPEYGEVIQLQGDQRQNIKSFLQKVGLESQIKLHGF-------- ---------------------------------FWKCARIGERKSPYVAVCCIAMAFSIL F-------------------------------------AEVSSILEERILGSATADLEET GRVLSIGDGIARVYGLKNIQAEEMVEFSSGLKGMALNLERDNVGIVVFGNDKLIKEGDIV KRTGAIVDVPVGEGILGRVVDALGNPIDGLGPLDSSQRSRVGVKAPGIIPRISVKEPMQT GIKAVDSLVPIGRGQRELIIGDRQTGKTAVAIDTIINQKRFNDGQNEKAKLYCIYVAIGQ KRSTVAQILKRLTDAGAMKYTIIVSATASDAAPLQYLAPYSGCAMGEYFRDNGKHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMHDNFQGGSLTALPIIE TQAGDVSAYIPTNVISIT------------------------------------------ ---------------AQFGSDLDAATQQLLNRGVRLTELLKQGQYMPMAVEEQVAVIYAG VKGHLDKMDPSRITTFEKEYLAHIRASHTDVLKTIRDEQQINPDTDAKLKQIVLNFLAGF MEALYSLPYTVLECPNLKLKKPQWLKTPSAMFMFSAVLLSYFLVTGGIIYDVIVEPPSIG STTDERGNSRPVAFMPYRVNGQYIMEGLASSFLFTMGGLGFIILDQTNKPMMPKLNRVLL LSIAFVSILVSFFMCRVFMRMKLP------------------------------------ ---------------IHHQKSRYIYDLFYRRKAISRELYEYCLKENIADKNLIAKWKKPG YENLCCLRCIQTRDTNFGTNCVCRVPKAKLEEGKIVECVHCGCRGCSGEYAQVAKMLGNG RLEAMCFDGIKRLCHIRGKLRKKVWINNSDIILVGLRDYQDAKADVILKYTPEEARNLKA YGELPEHVNINDGDDDNITFDDIDDILVRFLMKLSHETVTIELKNGTQVHGTIVGVDVSM NTHLKAVKMTLKNKDPVQLDSLSIRGNNIRYFILPDSLPLDTLLIDDTPKAKSKKSLLQK PKGEMTPEELSQREQEEFNTGPLSVLTGSVKNNTQVLINCRNNKKLLGRVKAFDRHCNMV LENVKEMWTEVPRTGKGKKKSKPVNKDRYISKMFLRGDSVILVLKNP-PILIDARGHLLG RLSALVAKTILQGQRVVIVRCEGINISGSFYRNKLKYLAFLRKRMNTNPKRGPYHFRAPS KIFWRTVRGMLPHKQSRGKEALNRLKVFEGIPPPYDKQKRVVVPSALKVLRLKPRRRFCD LGRLAHEVGWKYQNVVATLEAKRKVKSKQFYTKTKTEKKLREKALKAAPHQAIISSYG-A GDAEKGKKVFVQRCAQCHTVEKAGKHKTGPNLHGLIGRSTGQAPGFSYTDANIKKGITWG RDTLWIYLENPKKYIPGTKMVFAGLKKKAERADLIAYLEQSTKIFVERTLAIIKPDAVAE EIEDIIIRSGFTILQKRRVHLTPEQASDFYAEHYGKLFFPSLVAYMSSGPIIPLTLSREK GIAYWRELIGPTNTIKARQTHPDCLRSIYGTDDTRNGLHGSDSYASAAREIRFFFPDSVV EPVATGQAARDYLAKSVNPTLLKGLTELCKQKPEDSVLWLADWLIQNNPNKPKVKMFEAR LVQGSLLKKVLESIKDLLNEATWDCSSTGMSLQAMDSSHVSLVSLLLRSDGFDTYRCDRN LSMGIKLGSMSKILKCASNEDAITVKAGDNADTVTFMFESPNGEKVSDYEMKLMDLDTEH LGIPETDYSAVIKMPAAEFQRICRDLSQIGESVVISCTKEGVKFSASGDLGTGNIKLAQT ANVDKEEEAVVIEMQEPVCLTFALQYLNFFTKATPLSPTVSLSMSPDVPLVTEYKIGDMG YVRYYLAPKIEDGDDA-----------VARGRVVAVIGAVVDVQFDEGLPPILNALEVQN RTPRLVLEVAQHLGENTVRTIAMDGTEGLVRGQVCLDTGTPIRIPVGPETLGRIINVIGE PIDERGPVNAKATAAIHADAPEFVEMSVEQEILETGIKVVDMLAPYAKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMITSSVIDLEGDKSKVS---- ------------------------------------------------------------ ---------------------------------------------------TTVLSRGIA ELGIYPAVDPLDSTSRILDPNVVGAEHYATARGVQKILQDHKSLQDIIAILGMDDLSEDD KLTVSRARKIMRFLSQPFEVAEVFTGSPGKLVPLKDTIRGFQMILKGELDHLPEVAFYMV GPIEEVVSKAE------MLMPKKNRIAIYEHLFKEGVMVAKKDFHAAKHPELEIPNLQVI KLLTSLKSRGLVTEQFAWRHYYWYLTNEGIQYLRDFLHLPPEIVPSTLKRQTVGEDRAA- -----------------MGKANSKLRPEVLDDLRANTEFTDEEIQEWYKGFLKDCPSGNL SVEEFKKIYGNFFPYGDASKFAEHVFRTFDTNGDGTIDFREFICALSVTSRGKLEQKLRW AFSMYDLDGNGYISRQEMLEIVTAIYKMVGTVMKMPEDESTPEKRTDKIFRQMDKNLDGK LSLEEFIEGAKSDPSIVRLLQCDP------------------------------------ ------------------------------------------------------------ MIEKWQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCQDVYTPKSSRHHHTDG AYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQYQAAANFKMGYNNGKR MTNTKGYRRGTRYMFSRKFRTKGVIPLSTYMKVYRRGDIVDIKGNGAVQKGMPHKSYHGR TGRVFNVTPHAVGVIVNKRVKGRILAKRINVRVEHVKHSNCRLDFLNRVKENARKIKEAK E-----------------------------------------YVQVSPADPSMEWGDITD RAATATFWTELFRGLGITASMIFKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAICPAQAITIEAETRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEY STETHEELLYNKEKLLENGDKWETEIAANLQADHLYRMATQAKAAKTEGKNNHE-DKEQQ EAIEQIDEVQNEIDRLNEQASEEILKVEQKYNKLRQPSFQKRSELIAKIPNFWVTAFINH PQVSALLNEEDEEALQYLTKVEVQEFEDIKSGYRINFHFDSNPYFDNTSISKEFHLNSSK STPITWKAGKDLTKKTRKRNHEEQESFFSWFSDHGDAGADELGEVIKDDIWPNPLQYYLA SEIEEEGPDEE------KKLTKEEELLLQDFSRNVTTKSSALFYGNAFIVSAIPIWLFWR IHQMEPYILFAIMTLVSTYFVAFSYRNVKFLLKHKIAQKREEAVSREVMKKVSDDKKMTR KEKDERVLWKKNEVADYEATTFAIFYNNALYLVFMIIASFYLLRSFGPTVNYILSVVSSS ALLALLSTSTKATQGKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQT VCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNMDTFGRAKTWVKELQRQ ASPNIVIALAGNKADLRMVEYEEAQAYAEENSLLFMETSAKTAMNVNDIFLAIAKKLPKN EPGVDLNQDNMAEYLASIFGTEKDKVNCSFYFKIGACRHGERCSRLHNKPTFSQTVLLQN LYINPQNNAQVMMSDVEAQEHYDEFFEEVFTELEDKYGEIEEMNVCDNLGDHLVGNIYVK FRYEEDAEKAVNGLNLRWFNGRPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKP ISRELRRQLYGRRR-------------------------------MFLTRSEYDRGVNTF SPEGRLFQVEYAIEAIKLGSTAIGIQTAEGTVLAVEKRVTSPLIEASSIEKIMEVDSHIG CAMSGLIADSRTMIDRARVEAQNHWFTYNEKMSVESVTQAVSNLALAFGDDDADPGAMSR PFGVALLFAGIDEKGPQLFHMDPSGTFIQYDAKAIGSGSEGAQQALQEVYHKSMTLKEAC KQALTILKQVMEEKLNSTNVEMATVTPEQSYHLFSKDELEEVIKEIAQKTWEMSNSVETI SSVDEIYRYDKKQQQDILTAKPWEKDPHYFKHIKISALALLKMVMHARSGGNLEVMGLLL GKVDGPTMIVMDSFALPVEGTETRVNAQAQAYEYMAQYTDSAKQVGRLENVIGWYHSHPG YGCWLSGIDVSTQMLNQQFQEPFVAIVVDPVRTISAGKVNIGAFRTYPKGYKPPDEGPSE YQSIPLNKIDDFGVHCKQYYSLDISYFKSSMDRKLLESLWNKYWVNTLSSSSLLTNAEYT TGQIFDLADKLEQSEAQLGRGGFMEKKSEDKLAKATKDGCKNTIEAIHGLMSQVIKDKLF NQVGGLPRRIIKETQRLKAEPVPGIEAIPDESNARYFHVVVAGPKESPYEGGTFKLELFL PEEYPMSAPKVRFMTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPD DPLANDVADRWKTDEAQAIEIARQWTRMHA---EELLDYN-EEVDDTKDVKGTYVSIHSS GFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILSMDILCQAKSGMGKTAVFVLATLQ QLEPVDGQVSVLVLCHTRELAFQISKEYERFSKYMNTVKVAVFFGGLPISKDQEVLKKNC PHIVVGTPGRILALAKSLNLKHVKHFILDECDKMLEALDMRRDVQGIFRMTPHEKQVMMF SATLSKEVRPICKKFMQDPMEVYVDDDSKLTLHGLQQHYVKLKDNEKNRKLFELLDLLEF NQVIIFVKSVQRCMALAQLLVEQNFPAIAIHRAMTQDERLSRYQQFKDFQKRILVATNLF GRGMDIERVNIVFNYDMPDDSDTYLHRVARAGRFGTKGLAITFVSDENDAKVPPSYKDLG KDARDLFSTXFNYGFYKLECKTKTASGVSFTTDGSSNHDSGKISGGLETKYKWKDYGLTF LEKWNTDNTLGTEITIEDQIAKGLKLSFDTQFAPQTGKKSGKIKTAYKQEYVNVNCDVDF DFAGPTIHGAAVMGYNGWLAGYQMSFDKSKLTKSNFAIGYQGQDFTLHTNVNDGTEFGGS YHQKVSDDLETAVQLSWTSGSNATRFGLGAKYTPDKDSTFRAKINNSSQIGLSYKQCIRD GVDLTLSTLIEGKNFNQGGHKIGLGIDLEADTVREKALTDYRKKLLEHKEMDARLKEMRE QLKELTKQYDKSENDLKALQSVGQIVGEVLKQLTEDKFIVKATNGPRYVVGCRRQIDKSK LKSGTRVALDMTTLTIMRYLPREVDPLVYNMSIEDPGDVSYAQIGGLGEQIRELREVIEL PLLNPELFQRVGITPPKGCLLYGPPGTGKTLLARAVASQMACNFLKVVSSAIVDKYIGES ARLIREMFAYARDHQPCIIFMDEIDAIRRFSEGTSADREIQRTLMELLNQMDGFDALGKV KMIMATNRPDTLDPALLRPGRLDRKIEISLPNEQARMEILKIHAAPIAKHGEIDWEGVVK LSDDFNGADLRNVCTEAGMFAIRGERDYVIEEDFMKAVRKVADNKKLESKLDYKPVMPES LVSVVSRFYHDYMEHTSKKLKIIDAYLFYVLLTGVVQFLYCCFVGTFPFNSFLSGFISCV GTFVLGVCLRIQVNPQNKMEFQGIGPERAFADFIFAHVILHLVVMNFIGTLSSPSQLLPL ELVDKCIGSKIHIIMKNDKEIVGTLLGFDDFVNMVLEDVTEFESTPEGRRVTRLDQILLN GNNITMLVPGGEGPEVIDHYENPRNVGSMDKKDTDVGTGLVGAPACGDVMKLQIKVDDNG KIIDAKFKTFGCGSAIASSSLATEWIKGKSLDEAANIKNTDIAHELCLPPVKLHCSMLAE DAIRAALNDYKGKKEMLVLVLGDLHIPHRCSSLPAKFKKLLVPGKIQHILCTGNLCTKES FDYLKTLASDVHVVRGDFDENMNYPEQKVVTVGQFRIGLCHGHQVVPWGDTESLAPIQRQ LDVDILITGHTHKFEAFEHENKFYINPGSATGAYSALDS-ITPSFVLLDIQQSTVVAYVY QLLGDDVKVERIEYKKMGKILKPGKVVLVLSGRYAGRKAVIVKNYEEGTQDKPYSHALVA GVDRYPRKVTKRMGKKKIKQRSKVKSFVKVCNFNHLMPTRYSVVNFDKAVVNKDAFRDPA RRRKARREAKTKLEERYKTGKNRWFFQKLRFERTFIMVKPDGVQRGIIGEIMKRFEQKGF KLVASKLMQADEELLKKHYADLADKPFYPKLCKFMATSPVFPMVWEGGVVKTGRVMLGET DPAKSLPGTIRGDYCIDIGRNICHGSDSVESANKEIKLWFKDEELCNWSPAEESWVYE-- --------GKAKEKALRAKKAALKGVHDKRNRKIRTSVHFHRPKTLRLHRAPKYPRKSTP RRNRLDQFKIVKYPLTTESAMKKIEDNNTLVFIVDKRSNKPQIKVAVKKLYDIDVSKVNT LVRPDGEKKAYVRLAPDYDALDVANKIGIIMPSKQRMRIANEKHSKNVGQRGLVPKTLQQ AEDKYPVGPWMLALFVFVVCGSAVFQIIQSIRMXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMIRFI LIQNRAGKTRLAKWYMHFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIVYRRYAGL YFCICVDVADNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYSVVDEMFLAGEIRE TSQTKVLKQLLMLSSLEKPTIFSKIIDKTIPAEILHEDDQCLAFRDVTPQAPVHFLVIPK RQIPMLSSDAGLLGHLVVVANKIAQSENGYRVVINNGQDGAQSVYHLHVHVMGGRQMQWP PMGGLLSYFSGLFGSKERRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVTYKN LKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSMDRDRIGISKQELVSMLEEDELKKAI LVVFANKQDIEGAMTVTEVANSLGLSSLKNRKYQIFKTSAIKGEGLDEAMEWLANSLQTQ K----------------------------------------------------------- ----RTYGAEGRFTFTSHTAGEHTICLHSNSTAWFGGGQLRVHLDIQVGEHANDYQQIAA KDKLTELQLRVRQLLDQVEQITKEQNYQRYREERFRQTSESTNQRVLWWSIAQTLILLVT GFWQMRHLKSFFEAKKLVMFYHVSLEHEILLHPRYFGPNLLNIVKQKLFTEVEGTCTGKY GFVIAVTTIDNIGAGFIQPGRGFVVYPVKYKAIVFRPFKGEVLDAVVTQVNKVGLFTEIG PLSCFISRHSIPADMEFDPSSNPACYKTKDEEMVIQQDDEIRIKIVGTRVDATDIFAIGT LMDDYLGLVSRLYCKAVFTGFKRGLRNQHENTALLKIEGVTNIKDTDYYLGKRCAYVYKC RVKTACPGHEKASRIRVIWGKVTRPHGNSGCVRAKFRKNLPPKAMGRRVRVMLYMAKKTY DLLFKLLLIGDSGVGKTCLLFRFSDDAFNTTFISTIGIDFKIKTVELGGKKIKLQIWDTA GQERFHTITTSYYRGAMGIMLVYDITNAKTFDNISKWLRNIDEHANEDVEKMILGNKCDM EDKRQVSKDRGDNIAREHGIPFLETSAKANINVEQAFMDLAQAILNKMPQNEHIELHRKR YGYRLDYHEKKRKKESRAAHEQSAKAKKLRGIKAKLFNKKRHAEKVQMKKTIKMHEERKT KQKTDDNVPDGAVPAYLLDREGQSRAKVLSNMIKQKRKEKAGKWDVPLPKVKGVSEAEVF KVVKSGKTRRKGWKRMVTKATYVGDFFTRKPPKFERFIRPMALRMKKAHVTHPELKATFC LPIIGVKKNPNSTLYTSLGVITKGTIVEVNVSELGLVTQGGKVVWGKYAQVTNNPENDGC INAVLLV----------------------------------------------------- ---------------------------------------------RMFAPTKTWRRWHRR VNTNQRRYALCSAIAATGIPAIVMSKGHRIENTPEVPLVLNDKVEEYKKTKEAVGLLKKI KAWTDIEKVKSSRRFRAGKGKLRNRRRIQRRGPMIIYSQDNGICRAFRNIPGITLLNVSR LNLLKIAPGGHVG----------------------------------------------- ------------------------------------------------------------ -----------------GSGEQELATKTLQIQSKRFYLDVKQNRRGRFIKIAEVGSGGKK SRLLLAMSTAAEFRDHLTEFSEHYASLGPPNPDNLPEDGKLKSEVMIKDNRRYYLDLKEN QRGRFLR----------------------------------------------------- -----------------------------------------------QEKKIRDAQMRAT INQKLIETGEREKLKELLRTRLIECGWRDQLKAYCKEVVRQKGLEHITVDDLVAEITPKG RALVPDQVKKELLQKIRAFLAQQQNMNIRNGRPEDLMNMQHCNLLCLPENYQMKYYFYHG LSWPQLSYVAEDEKGKIVGYVLAKMEEDPEDSVPHGHITSLAVKRSHRRLGLAQKLMDQA SRAMVESFNAKYVSLHVRKSNRAALHLYANTLKFQISEIEPKYYADGEDAYAMRRDLSEF AEK-MSHTILLVQPGRKPESRTYSDYESVNECLEGVCKIYEEYLKRMNPNSPSITYDISQ LFDFIDQLADLSCLVYQKTTATYVPHNKDWLKEKIYELLRRQAGRMADPTEEKKDDGGKR VVHTYPLVRQSDMNEEMRTEAMELCVTACEKFSNNNESAAKLIKETMDKKFGASWHVVVG EGFGFEITHEVKNLMYMFFAGTMAICLWKCSMSHRKFSAPRHGSLAFLPKKRSKRHRGKV KCFPKDDPSKPIHLTAFLGYKAGMTHILREVDRPGSKTNKKEVVEGVSIVETPPMVIVGV VGYIDTPRGLRTFKTIFAEHLSEECKRRFYKNWYRSKKKAFTKAAKKWQDDAGKKEIEKD FAKMKKYCSVIRVIAHTQMKLLKKRQKKAHIMEIQVNGGTIAQKVDWGREHLEKSVSVSN VFAQDEYIDIIGVTKGKGYKGVTSRWHCKKLPRKTHKGLRKVACIGAWHPARVSFSVARG GQKG------------------------VIKNNASTEYDLTEKTITPLGGFPHYGEVNND F----------------------------------------------------------- ------MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLG LWDTAGQEDYDRLRPLSYPQTDVFLICFSLISPASFENVRAKWYPEVSHHCPNTPIILVG TKLDLREDKETVEKLKEKKLSPITYPQGLAMAKEITAVKYLECSALTQKGLKTVFDEAIR AVLCPKPNTRKRKTCTLLIFDPSLKKKKKKKTPFDLEAALEDFDLD-NLGKKKKKKKKPF ELTELEESLPKEEKTLPSKKKKSDTDRDYTYDELLKRVFDIMREKNPDMVAGEKKRFVMK PPQVMRIGTKKTMFANFTETTKMLHRQPKHLLAFLLSELGTSGSIDGSNQLIIKGRFQQK QIEIVLKRYIKEYVTCHTCRSPETILQKDTRLYFLQCETCGSRCSVTSIKSGFQAVTGRR AAIRARTS---------------------------------------------------- ------------------------------------------------------------ ------------------------------LVFDYTKHPSKPDPSGECHPELRLKGHQKE GYGLSWNPNLNGHLLSASDDHTICLWDINTTPKEGRCIEAHTIFTGHTSVVEDVSWHLLH ESLFGSVADDQKLMIWDTRSNTTNKPSHTVDAHTAEVNCLSFNPYSEFILATGSADKTVA LWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQSAEDA EDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEEPDTPAS ELEMPAPSRARVYADVNTHRPREYWDYESHVVEWGQQDDYQIVRKLGRGKYSEVFEAINI TNNERCVIKILKPVKKKKIKREIKILENLRGGTNIISLVAIVKDPVSRTPALIFEHVNNT DFKQLYQTLTDYDIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLA EFYHPGQEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPFFHGHDNY DQLVRIGKVLGTEELYQYIDRYQIDLDLRFNDILGRHSRKRWERFVHNDNQHLVSAEALD LLDKLLRYDHAERLTAREAMEHPYFYPIVKEQVPETLLKKRKQKAEKNFEKKKEIFKRAE KYIKEYRVKERDEIRLARQXRKHDNFYVPPQAKLAFVVRIRGINGIHPKPRKVMQLLRLR QINNGTFLKLNKATTEMLRLAEPYLTWGYPNLKSVRELIYKRGFGKVDGRRVPLTDNAII EEQLGKFGIICMEDLIHEIMTVGPNFKQANNFLWWFKLNTPNGGWKKKNNHFVDGGDYGN REDKVNGLLKRMLKFLLLVNKQGQPRIAQYYEHISEDSKHGIQADXIRKCLSRSDKQCSF FDYRNFKVVFRKYATLYFIIGIDEEENELAVFEFIHNIVETFDKYFEKVCELDIMFN--- -----------------------------------------------MSKAHPPELKKYM DKKLSLKLNGARIVTGTLRGFDPFMNLVIDEAVEETRAGEKHEIGMVVVRGNSIILLESF DRVEFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTI RLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFQQTSKWIDDVRTERGSDVIIM LVGNKTDLSDKRQVSTEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMEQTEK PPMIEVKLKDTPAEPQQ----YEMCVGLVKGHKVTTQKPRPSRRKGAQTKRAKFIRDIVR EVCGFAPYERRCIELLRISKDKRALKFCKKRLGAHIRGKRKREEMQAVIQQMRKAMVDES TKRSLAQIPLLKTKAGPRDAELWIQRLKEEYQSLIQYVENNKKADNDWFRLESNKDGTRW FGKCWYIHELLKYEFEVEFDIPVTYPTTAPEIAIPELDGKTAKMYRGGKICMTDHFKPLW ARNVPKFGIAHAMSLGLGPWLAVEIPDLLEKGIISHKE-LDKFDFLDDVRRMNKRQLYYQ VLNFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNYREEPIRVGE IVVFKVDGREIPIVHRVLKVHEKETGSVKFLTKGDNNQVDDRGLYAPGQLWLEKKDVVGR ARGFVPYVGIVTILMNDYPKFKYAILALLGLFVLIHREMSTMNPEYDYLFKLLLIGDSGV GKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYR GAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEY ADQLGIPFLETSAKNATNVEQAFMTMAAEIKNRMGPAPSAQSVKINPSTPIKPSGGGCCE DTLGEEVLRMGTDEIVSRTRLLDNEIKIMKSDIMRIGHELQTQKEKIKENAEKIKVNKTL PYLVSNVIELLDVDPQDQAEEDGANVDLDSQRKGKCAVIKTSTRQTYFLPVIGLVEPENL KPGDLVGVNKDSYLILETLPAEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELIEAVVLP MTHKERFEALGIQPPKGVLLYGAPGTGKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGA KLVRDAFALAKEKAPAIIFIDELDAIGTKR--------------MLELLNQLDGFHPNHR IKVIAATNRVDILDPALLRSGRLDRKIEFPAPNEEARARIMQIHSRKMNVSVDVNYEELA RC----------------------------------------------------KDAADQ NFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRQDKRVKLQIWD TAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDNAQVVLVGNKC DLEDERVVSTERGKQLADQLGLEFFETSAKENINVKAVFERLVDIICDKMSESLDSDPTQ TKRLTENPNPQNAGCQC---HQMAINRDYISQPRLTYKTVSGVNGPLVILDGVKFPKFAE IVRLTLADGSQRSGQVLEVSGSKAVVQVFEGTSGIDAKHTTCEFTGDILRIPVSEDMLGR VFNGSGKPVDKGPSVLPEDFLDIQGQPINPWSRIYPEEMIQTGISAIDGMNSIARGQKIP IFSAAGLPHNEIAAQICRQAGLVKLPGKSVMDDHEDNFAIVFAAMGVNMETARFFKQDFE ENGSMENVCLFLNLANDPTIERIITPRIALTTAEFLAYQCEKHVLVILTDMSSYAEALRE VSAAREEVPGRRGFPGYMYTDLATIYERAGRIEGRNGSITQIPILTMPNDDITHPIPDLT GYITEGQIYVDRQLQNRQIYPPINVLPSLSRLMKSAIGEGMTREDHSDVSNQL-ACYAIG KDVQAMKAVVGEEALSQDDLLYLEFLQKFEKNFISQGHYENRTIFETLDIGWQLLRIFPK EMLKRIPAAKIAKYYPRDG-GPGFVGIKFCQECNNMLYPKEDKENRILLYACRNCDYQQV ADNPCIYVNKIEHEVDELTQIVADVIADPTLPRTEDYPCPKCNHKEAVFFQSQTRRAEEG MRLYYVCTLPSCAHRWTE------------------------------------------ -------------------------GAEVQWSSCNIFSTQDHAAAAIAKTGVPVYAWKGE TDEEYVWCIDQTIMFGD-KPLNMILDDGGDLTNLVHEKYPTLLKGIKGLSEETTTGVHNL YKMMAKGDLKVPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDIMLAGKVAIVAGYGDV GKGSARALRAFGARVIITEIDPINALQAAMEGYEVTTMEEACSIGRIFVTATGCADIITG KQFEKMPEDAIVCNIGHFDCELDVKWLTDNATHKENIKPQVDRYTLKNGRHVILLADGRL VNLGCAMGHPSFVMSNSFTNQVLAQIELWSKADKYELGVHVLPKKLDEEVALAHLDHLGV KLTKLSEEQSKYLGIPVEGPFKPDLYRYAEEVEQ-PGTTVEEPLDLIRLSLDERIYVKMR NDRELRGRLHAYDQHLNMILGDVEETVTTVEIDEETYEEIYKSTKRNIPMLFVRGDGVIL VSPPMRT------ENLSPQIIRQVSKELTSLICDPPEGIKVYPNEEDITEIHATIEGPAG TPYAGGLFKMKLVLSKNFPSEPPKGFFLTKMFHPNVAKNGEICVNTLKKDWKAELGIKHV LLTIKCLLIYPNPESALNEEAGKMLLEQYGDYSMRAKMYTEIHAKPMFKSVLDAAKNSPF ASPFGLKVNENRTIAAAQEEYSCEFGSTKYFALCGFGGILSCGITHTAVVPLDLVKCRIQ VDPAKYGGIVNGFKVTVKEGGMKELAKGWAPTFFGYSAQGLCKFGFYEVFKSVYGNMLGE EKAFLWRTSLYLAASASAEFFADIALCPFEACKVRIQTQPGWANTLREGFPKLHAEEGMW GFYKGIVPLWGRQIPYTMMKFACFERTVEALYKFVVPKPRADCSKSEQLVVTFVAGYIAG VFCAIVSHPADVIVSKLNKEKGSSAVDIAKKLGFMGMWQGLFPRIIMIGTLTALQWFIYD SVKVAFRLPRPPPPEMPESLKQKL-HWKMERLLDVSMLGTIPAGLICVTDVMISTVLLHT HWGLTGVCGDYLHLSIMSYGGLLYLTFNDIGFGAAVRLLFTSLNVQPEEDASELQFPKEF ENAETLLVSEVQRKQQNENAEEEQELSEAFMKTLGYTSRFSKFKNRETITSVRSLLMQKK LHKFELAAIANLCPENADEAKALIPSLEGRFEDDELQQILDDIKTKRSFQYNQQPHLAKQ DLSTLDVAKLTPSSPEVISRQATINIGTIGHVAHGKSTVVKALSGVHTVRFKNELERNIT IKLGYANAKIYKCEDPSVVRPACYTSRGSSHVDEFPVDVPGGGKFRLVRHVSFVDCPGHD ILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQ AREQYEQILKFVQGTIAEGAPIIPISAQLKYNIDAVCEYIVKKIPIPPRDFTKEPRLIVI RSFDVNKPGFEVDDLKGGVAGGSILRGVLKVGQEIEVRPGIVSRDAEGKLTCQPIFSRIV SLFAEQNDLQFAVPGGLIGVGTKIDPTLCRADRMVGQVLGAVGHLPEIYTELEISYFLLR RLLGVRTEGDKKGAKVQKLSKNEILMVNIGSLSSGGRVLAVKADLAKIGLTNPVCTEIGE KIALSRRVEKHWRLIGWGQIRRGVTIKPMAELLLDSNIRIWVFLPIVVITFLIGILRHYV TILLSSEKKVELQQIADSQALIRSRNLRENGRFIPKQSFLMRKHFFNEGEKAFLVKNPMT DPTMMTDMMKGNITNVLPMIIIGGWINWAFSGFLTTKVPFPLTLRFKPMLQRGVELSSLD ASWVSSASWYFLNVFGLRSMYNLILGQDNAADQTKVMQDQMSGAAMAMPPDPSKAFKGEW EALEITEHAWALDGVEEEV-MFLWDWFAGILNFLGLYKKSGKLVFLGLDNAGKTTLLHML KDDRMAQHVPTLHPTSEELSMGGMRFTTFDLGGHLQARRVWKDYFPAVDGIVFLVDVFDR QRFTEAKAELDSLLTDEQISSAPVLILGNKIDKPGAASEDEIRGVFGLHGQTTGRGVVNR SELRPMELFMCSVLKRQGYGEGFRWLAQYINIIRRNRPGTKAEGWCSWPDESFEEMDSTL AVQQFIQQAIRRDFANIEEILTPPEGQDEGVWKYEHLRQFCMELNGLAVKLQAECNPETC TQMTATEQWIFLCAAHKTPKECPAIDYTRH----AACLLNSNKYFPSRVSIKESSVAKLG SVCRRVYRIFSHAYFHHRSLFDEYENETALCKRFTVFVTKYNLMSKDNLIVPILEE-MPN IKLQSSDGETFEVDVEIAKQSVTIKTMLEDDEDEEEAVPLPNVNAAILKKVIQWCTYHKD DPPPPEDDENKEKRTDDISSWDAEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMI KGKTPEEIRKTFNIKNDFTPAEEEQVRKENEWCEEKXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSASAVYL LDVKGKVLICRNYRGDIDMSVIDKFMPQLMDREEEGILTPIITHGPTTFVYIKYNNLYLV ATTKKNSNVALVFSFLHKIVHVFCEYFKELEEESIRDNFVIIYELFDELMDFGYPQTTDS KILQEFITQEGHKLEVAPRPPMAVTNSVSWRSEGIKYRKNEVFLDVIESVNLLVSANGNV LRSEIVGAIKMRVYLSGMPELRLGLNDKVLFESTGRGKSKSV------------------ ------------------------------------------------------------ ---------DADSPKFKTTVGSCKWLPEKSVVIWSIKSFPGCKEHLMRAHFKLPSVQAEE AEAKPPIYIRFEIPYYTVSGLQVRYLKI--------------------------MGILDR IADIEAEMARTQKNKATMGHIGLLKARLAKLRRELIEPKGGGGGTGEGFDVAKTGDARIG FVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIKYKGAKVQLLDLPGIIEGAKDG KGRGKQVIAVARTCSLIYIVLDVLKPLQHKKLIEHELEGFGIRLNKKPPNIFFKRKDKGG INLTATVAQSELDLDLVKSILGEYKIHNADITLRYDSTTEDLIDVVEGNRIHIPCIYVLN KIDQISIEELDIIYKIPHCVPISAHHKWNFDDLLEKMWEYLQLVRIYTKPKGQLPDYEAP VVLKDGDSSVEDFCNKLHRSILKEFKYALVWGSSVKHQPQKVGRDHILNDEDVVQIVKKM AKHHPDLIFCRKQPGVAIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGSYQGRCVIC GGPGVSDAYYCKECTIMEKDRDGCPKIVNLGSAKTDLFYERKKYGFKKRPNLPPISGDKL AGKSDLRKIPVPANRYTPLKENWMKIFTPIVEHLHLQVRFNLKTRNVEIKTCKETRDIGA LQKAADFVKAFTLGFEVDDALALVRLDDLYLESFDITDVKPLKGDHLARAVGRIAGKGGK TKFTIENVTK-------------------------------------------------- --RIEVSKPVVELDGDEMTRIIWADIKDKLIFPYLKVECLYYDLGLPHRDNTDDQVTIDS AHAIKKHNVGIKCATITPDEQRVEEFALKKMWLSPNGTIRNILGGTVFREPILCKNIPRL VPGWKGPISIGRHAFGDQYRASDMVIKGDAKFEIVITDPSGKENRTEVFNFKD-GGVLMG MYNTDESIRGFGHSCMQYALGKNWPLYLSTKNTILKRYDGRFKDIFEEIYEKNYKADFEK QGIWYEHRLIDDMVAQALKSDGNFVWACKNYDGDVQSDVVAQGYGSLGLMTSVLMCPDGK TIEA--------------QKGNPTSTNPVASIFAWTQGLLHRAKLDDNKDLAHFCETLEK ACVDTVDSGKMTKDLAGCIHGLKNVRPEHYLYTGDFLDAIREELEMGKLLSKIFGNKEMR ILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWR HYYTGTQGLLFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPEAMKPHEI QEKLGLTRIRDRNWYVQPSCATTGDGLYEGLTWLTSNAKSFGDLKSDAGLKVFNEFLADK SYVEGFQPSQADAVVFSAVSGPNSKYNHALRWYNHIKSYGNETSKFPGAKKAVTEYGPAG TDKADDDDDFDLFGSAAEKLKEERLAAYAAKKSPALIAKSNIILDVKPWDDETDMKELEK CVRTVETDGLLWGASKLVPLAYGIRKLQICCVVEDDKVGTDFLEEEICKFEDYIQSVDIA AFNKIKVQEVREVTRIERIGAHSHIRGLGLDDALEARNVSQGMVGQTFARRAAGIILEMI KDGKIAGRAILIAGQPGTGKTAIAMGMAQALGLDTPFTAIAGSEIYSLEMSKTEALTQAF RKSIGVRIKEETEIIEGEVVEIQIDRPATGTGAKIGKLTLKTTEMETIYDLGAKMIESLT KEKVQAGDIITIDKATGKITKLGRSFTRARDYDAMGAQTKFVQCPEGELQKRKEVVHTVS LHEIDVINSRTQGFLALFSGDTGEIKPEVREQINAKVAEWREEGKAQIVPG--------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------MAEFDLTTRMGQYLDRHLVFPLLEFLSVK MIFDETEMLRGKLDLLSNTNMVDFAMDVHRSLYPDQEVPATLREKRATVVSELKRLQTET EQITKIFEDSEVMIQAARDGRQLYESLAKTYDFRPEMVDMLYTYAKFQYECGNYSGAAEY LYFVRVLLPPNDKNYLNALWGKLASEILMQNWDTALDDLNRLKDVIDNPLGSLQQRTWLI HWSLFVFFNHPKGRDHIIDMFLYQPQYLNAIQTMCPHILRYLTTAVITNKTVLKDLVKVI QQESYTYRDPITEFLECLYVNFDFDGAQQKLRECETVLVNDFFLVACLHDFIENARLFIF ETFCRIHQCISINMLADKLNMPPDDAERWIVNLIRNARLDAKIDSKLGHVVMGTQAVSPY QQVIEKTKGLAFKSQMLVVNIEKKIGAK-MGVTVEVINRGDDCSYPQKGQKVTVHYTGTL TNGKKFDSSRDKNKPFVFTIGAGQVIKGWDEGVAKMSLGERSKLTCTPDYGYGSRGAGGV IPGNATLFFDVELLKI------------------PSVRKTHCSGRKHKENVRVYYQKWLE EQVQKLVDDTTAAFKADRPGQG----GGPNAGPPNA----PGGP-GPMGGP-PGG--PPV --------PMQMMMGPPEPLTLERDIQRAIELLEHLQKSGEMPRLAALAKVLQSDFCTAV REVYEHVYETVDISGSPEIRANATAKATVAAFAASEGHAHPRVVELPKTEEGLGFNVMGG KEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGVSVEGEPHEKAVDLLKAAQGTVKLV VRYTPKVLEEMEARFDKQRTARRRQ----------EGTVHFKEEFWESNWVNSEHKGSEQ GKFIWTAGKFYNDPEADKGIQTSQDARFYGLSAKFDQAFSNEGKTLVIQFSIKHEQNIDC GGGYAKVFGSDLDQKDMHGDSPYLIMFGPDICGPGTKKVHVIFNYKGKNLLTKKDIRCKD DVFSHVYTLIVNSDNTYEVKIDNKKVESGELEADWDFLPPKKIKDPSAKKPDDWDDRENI DDPEDSKPDDWEQPEHIPDPDAKKPDDWDDEMDGEWEPPMIDNPDYKGEWKPKQIPNPNY KGVWVHPEIDNPEYTPDDSLYKYSDIGAIGFDLWQVKSGTIFDNIFISDDVALAEKHAED TWGKMKDGEKKMKDDQDEEERKKREEEEKAKKEEEPKEEEEEEEXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNVFRLVGDLSHLLAIILLLLKI WKTRSCAGISGKSQIMFAMVFTARYLDLFTNFISLYNTCMKVFFIGAAYLTVYLMLMKFR ATYDSNHDTFRMEFLIVPVGGLAFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGE AESITSHYLFALGSYRALYILNWVYRYYFEGFFDLIAVVAGCVQTVLYCDFFYLYVTKVW KGKKLTLPAMKIEEVKSTTKTQRIAVHSHVKGLGLDENGFAHQSAAGLVGQELAREAAGI VVEMIKSKKMSGRAVLLAGPPGTGKTAIALAIAQELGSKVPFCPMVGSEVYSSEIKKTEV LMENFRRAIGLRIKETKEVYEGEVTEVTPVETENPMGGYGKTVSHVIIGLKTAKGTKQLK LDPSIYESLQKEKVEVGDVIYIEANSGAVKRQGRSDTYATEFDLEAEEYVPLPKGDVHKK KEVIQDVTLHDLDIANARPQGGQDIMSMMGQLMKPKKTEITDKLRKEINKVVNKYIDQGI AELVPGVLFVDEVHMLDIECFTYLHRALESTIAPIVIFATNRGKCSIRGT-DILSPHGIP LDMLDRLMIIRTLPYSQEEMVQILKIRAETEGITVNDDSTNLLGDIGVKTTLRYATQLLT PSSLLAKINGKETIAREEIEEINELFYDAKSSAKILAAHEDKYMKDFEVDEEGDQGLQKL KEKVKKRKGRGFATRSGVEEYEAMETSGPGPQRSVEGWILFITNVHEEASEDDINDLFGD YGEIKNLHLNLDRRTGFIKGYALVEYETFSEAQAAMENLNGQEILGQKINVDWGFVRGPV SKKMSYQLYRNTTLGHTLQESLDELISCSQISPSLALKVLLQFDKAINNALATRVKTKYN FKGHLNTYRFCDNVWTFVLNDVDIRKVDKVKIVACDGK-TFLFTSESVGEGHPDKICDQV SDAVLDAHLKQDPNAKVACETAAKTGMIMLLGEISSKAHVDYQKVVRDAIKHIGYDDSCK GFDYKTCNVLSALEEQSPDIAQGVHEGRSEEETGAGDQGLMFGYATDETEECMPLTVVLS HKLNAKIAENRRNGVMPWARPDSKTQVTCEYRMEKGACVPLRVHTVVISVQHSDDITTDQ LRKELMEKVIKVVIPEKYLDERTTFHLQPSGRFVIGGPQSDAGLTGRKIIVDTYGGWGAH GGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVAEPLSIFVSSYGT GVRPDSEILKIIKDNFDLRPGVIVRDLDLKKPMYQRTAAYGHFGRPEFSWEEAKKL--MA GSALKRLMAEYKQLTLNPPEGIVAGPVNEENFFEWEALITGPEGTCFEGGVFPAHLTFPS DYPLSPPKMKFTCDLFHPNIYPDGRVCISILHAPGDDPMGYESSAERWSPVQSVEKILLS VVSMLAEPNDESAANVDAAKTWREDRIKFEEIAFRTVKKSLGLMRLEKCYFCSSTVYPGH GVTFVRNDCKVFRFCRSKCHRAFKAKRNPRKVRWTKAFRKASGKDLAVDPSFEFEKRRHV PVKYDRELWNKSVSAMKRVEEIKQKRQAQHIMNRLKKGKELRKQADIKDVEKNIHLIRAP ---MATYKIVMIRHGESEWNKENRFCGWFDADLSELGTNEAKSAGQMLKEQGFSFDIAFT SVLKRAIKTLFLVQEELDLHWIPVVRHWRLNERMYGALQGLNKSETAAKHGEDQVKIWRR SYDTPPPAVEMSDERFPGNDPKYQYVDKNLLPKCECLKDTVGRVLPFWYDVIVPEILKGQ KVLIAAHGNSLRAMVKYLDNMSDEEIMGLNIPTGIPLVYELDANLKPVKHYYLASEEQVK AAIDKVAAQGKAKMELEDTYYDKGEYIETASGNKVSRQSVLCGSQNIVLNGKTIITSECI IRGDLANVRIGRHCVISKRAVIRPPFKKFSKGVAFFPLHIGDHVFIGEDSIINAAQVGSY VHIGKNCVIGRRCVLKDCCAIADNTVLPPETVVPPFTYFSGSPGMSFLFGSRSNKTFKPK KNIPEGTHQYDLMRHAAVTLGSGNLRQAVALPEGEDLNEWVAVNTVDFFNQISMLYGTVT EFCTEQSCPVMSAGPKYEYHWADGHTIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKI GVPFPKNFLSIAKTILKRLFRVYAHIYHQHFQQVIQLAEEAHLNTSFKHFVYFVQEFGLV DKRELAPLQGLIDKLTAKEMGIDIKHKNDRKVHRTEPKSQDIYLRLLVKLYRFLARRTNA KFNRIILKRLFMSKTNKPPISLARVVRNMKKTGRENKTCVIVGTVTDDIRIFDVPKLKIC ALRVTGSAKSRILKAGGEIITFDQLALKAPKGQNTVLIQGPRKARDAYRHFGRAPGVPHS STAPYVRSKGRKFERARGRRASRGYKNELKQGDIHDSDYVASTVKLLLRIVSQTKWTTIG DLMKTVCEEGKRLMEAEPSETTVGNMVRRVLKIIREEYIVDAIQELVSELETSSQAQEHI HSNEVISTVETFLKKKFQVMVVEYHGHDLAASLAKSNIETTVITDSAVFAMMSRVNKVIV GTHTVMANGGLKAQGIHAIALAAKHHSVPLLVCAAMFKLSPQYLCSYDDAFNKFVSPQSI YNPVFDYVPPELVTLYVSNIGGNAPSYVYRLLSELYHMIIPIRCFTCGKVIGNKWEAYLG LLQAEYTEGDALDALGLKRYCCRRMLLAHVDLIEKLLNYAPLEKKSPEPVEGRKHIDVQT ELYLEELSDRVEEADVECQTDAFLDRPPSPLFIPAKSGKDIATQILEGELFDFDVEVKPI LEVLVGKTMEQSLLEVMEEEELANLRSQQRAFEELRNAELVEQQRLEEQERRHKEEKERR MKQQREILRKERETSEKIAARAFAQSYLADLVPSVFGTLADNGYFYDPVERDVEQGFMPW LMDEVESKLNKVVVSRATVDSIIRQVVAARAAEYAKMKVNGELKEYKVIGRALPTDKNRV PPLYQMRIFATNKLTARSRFWYFCSMLKKMKKTKGEILCCQQIFDKRPTKVKNFGIWLRY NSRSGTHNMYREYRDVLTCGAVTQCYRDMGARHRARACSIQVMRVEEIAAAKCRRSNIKQ FHDSHIKFPLTHRIGKRLHAPRFTTKRPHTTFSAHNEMENFWRKNENRPVAPWINYQWEF PMLTSLTHRTTGIVMAAGLYGIGIGYLLGPDTFPQYVDLLKSWNLGPAFWFPFKSLMAFP LIYHYLNGFRHMWFDFKGGYEIEAQYRSGYICLGGAAY------LSAYRDQHFKGNRSEQ EKLLLGSTTLYVGNMSFYTTEEQAYELFGRCGDLKRIVMGLDKYRKTPCGFCFVEYYTRE DAEHAMRYVNGVRLDDRIIRTDWDAGFKEGRQYGRGKSGGQVRDEYRQDYDSGRGGYGKI TASKLKPNYTLKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGH KLGISDVAWSTDSRLLVSASDDKTLKIWDLATGKCMKTLKGHSNYVFCCNFNPQSNLIVS GSFDESVRTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG KWIVSGSEDNMVFIWNLQTKEIVQKLQGHTDVVLCCACHPTENIIASAALENDKTIKLWK SEVMIIYKDVISEDEMFSDIYPDCVWKVKGKDDINIGANASSGVNIVLAGKKDYQIYIKG YMGKIKAYQFFMGIALLKWETPEMFFF---------MAVEFDGGVVIGADSRTTTGSYIA NRVTDKLTKITDNIYCCRSGSAADTQAIADIVSYHIGFHAMEMDQDPLVKTAASVFQELC YGYRDQLSAGIIVAGWDKKLGGQVYSVPLGGMCVRQPFTIGGSGSTYTYGYCDATFKEGM TKEECLNFCTNMLALAMARDGSSGGIIRLAAITKDGVERKTILHPDLPKF---------- ------------------------------------------------------NMEDNE DAESQKSEVKLGKLQFSLDYDFQKGELAVGVIQAADLPGMDMSGTSDPYVKVYLMPDKKK KFETKVHRKTLNPVFNETFTFKVPYAEIGSKTLTFAIYDFDRFSKHDQIGLVQVPMNSID ---------------------------------------------------------LSD PYVKLSLMLNGKRIKKKKTTIKKCTLNPYYNESFSFEVPFEQIQKVQLYITVVDYDRIGT SEPIGHVVLGCNASGTELRHWSDMLANPRRPIAQWHTLQEVPEK-MVLADLGRKITTALR SLSTATVINEEVLNSMLKEICKALLEADVNIRLVKKLRENVRSVIDFDEMAAGLNKRKMI QSAVFKELVKLIDPGVKAWTPSKGHPNIIMFVGLQGSGKTTTCTKLAYYYQKKGWKSCLV CADTFRAGAFDQVKQNATKARIPYYGFMSKGNEQESMARLKKLMTIMDS----------- ----------------------NDSELDSHE--GARLFTRGRIQRVARGAGVSARDVQEL LTQKFAQMVKKMGGIKGLFK-GGDMAKNVQAQMHKLNQQMAKMMDPRVLQSMGGMPGLHT MMRQFQQGAMSIMSYNGAAIVAMKGKDCVAIASDRRFGIQAQTVGMDFQKIFEMGPHLYI GLPGLATDVQTVSQRLKFRLNLYELRENRRIKPKTFLSMVSNLLYERRFGPYFVEPVIAG LDPKTMEPYVASLDLIGCPMVTEDFVVSGTCTEQLYGMCESLWEPDLGPEDLFETISQAL LNAVDRDAVSGWGVIVHVIEKDKVTTRTLKARMDMTSKDYYFDSYAHFGIHEEMLKDEVR TLTYRNAMIHNKHLFKDKVVLDVGCGTGILCMFAARSGAKRVIGIECSSIIDYAEKIVKA NNLDSVISLVKGKVEEVSLPDGIDKVDIIISEWMGYCLFYESMLNTVIYARDKWLRPGGL IFPDRATLYITAIEDRQYKDEKINWWDSVYGFDMSCIRKVAIQEPLVDVVDPKQVVTNSC LVKEVDIYTVTEGDLAFSAPFHLQCRRDDYVQALVTFFNIEFTKCHKRTGFST------- ---------------------------------------------------------MVR EDRTTWKSNYFIKIVQLFEEYPKCFIVGVDNVGSKQMQQIRIALRVLMGKNTMMRKAIRG HIEQMPVLEKLLPHIKGNIGFVFTKEDLSDIREKILQNKVAAPAKAGALATQDVKIPAQN TGLGPEKTSFFQALSIPTKISKGTIEILNDLILLKEGEKVGASEATLLNMLKISPFSYGL QVQQVYDSGTVFEPAVLDITDDDLRVRFMEGVTRIAALSLAIGYPTVASAPHSIINGFKN LLAVAAVTDIEFKEAQQMKESSAKGKLLAVIGDEDTCTGFLLGGIGELNKHRQPNFLVVE KTTTVSEIEEAFKTFTGRDDIAILLINQNVAEEIRHIIDAYTDPIPSVLEIPSKEHPYDA SKDSILRRAKGMFSAEELRGNESSLPMELCSNFDPDEIKRLGKRFRKLDLDNSGSLSVDE FMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGMSQFSVKGDKESKLRFAFKIYDMD KDGYISNGELFQVLKMMVGNNLKDAQLQQIVDKTIIHADTDGDGKISFEEFCTVVRNMDV HKKMVVDVMTYITSWEEFAKAAERLYVSDPWKCRFVIKYCHSKGQLQVKLTDDQVCLQYR SEHAADVKKLEKLTSMLMRHMATKDLFEEVKLYRGVREREKLDNMADLYAVINTLQNLEK AYIKDLVTPKEYTAACSKLLVQYKAAFKQVESEEYPSVEVFMRKCKLDGPAALERIKEDR PITIKDDKGNTSKCIAEIVSLFITVMDKLRLEIRAMDEIHPDIRDLSDNMKRLSILPADF EGKAKVDSWLQTLGAMQASDELTDSQVRQLLFDLESAYSDFNRVLHNMLSRMVKEHQARQ QIRKEQQEKLRKEAANATALTHALVDHLNAGVAQAYVNQKKLDTETKILQANAGHFAKQT MLWLRLVEDFNQSLKEIGDVENWARSIETDMRTISSALEYAYKGRVVEKQIGGEKNGGKR MVRINRLPRFYPTEDRPKKLLSRFDDHKHKLRSTITPGTVLILLAGRHKGKRVVFLKQLS SGLLLVTGPFHLNGCPLRRINQIYVIATKAKVNIDEVKVPDNVNDEYFRRKKLRKPKHAE GDIFDTKKEEYAVTEERKKDQQEVDSQVLAAVRKHAEKKLMFGYLGATFSLKNRVYPHTL VFLEWLFGKKKTPQEMLRQNQRALNKAMRDLDRERAHMEQQEKKIIADIKKMAKAGQMDA VKIMAKDLVRTRRYVKKFILMRANIQAVSLKIQALKSTDSMAQAMKGVTKAMSTMNKQLK LPQIQKIMMEFEKQSEIMDMKEEMMNDAIDDAMGDEDDEEESEAVVQQVLDELGLQMTDE LSNLPQTGQSGAKQPVGATDADADLEARLENLRRQ--YCDFCLGDEKENKKTGHKEELVS CSDCGRSGHPTCLQFTANMIISVKKYPWQCIECKSCGLCGTSDNDDQLLFCDDCDRGYHM YCLTPPLSEPPEGS------------SMERTINLYPLTNYTFGTKEALFEKDPSVQARFQ RMRDEFEKIGMRRSVEGVLIVHEHGLPHVLLLQLGTTFFKLPGGELNATEDEVEGLKRLL TETLGRQDGAPMDWVIENSIGNWWRPNFEPPQYPYIPAHITKPKEHKRLFLVQLPEKALF AVPRNYKLVAAPLFELYDNAAGYGPIISSLPQALSRF-----FTPSGTTPTGQKAMAMAT PTPGHLMSMTPEQLQAYTLQREIDERNRPLTDDELDTMFPPGYKVLQPPAGYVPIRTPAR KLTATPTPMAGTPMGFRMQVSMVDMQPKGNLPLLKPDDMQYFDRKIMKLLLKIKNGTPPM RKAALRQITDKAREFGAGPLFNQILPLLMSPTLEDQERHLLVKVIDRILYKLDDLVRPYV HKILVVIEPLLIDEDYYARVEGREIISNLAKAAGLATMISTMRPDIDNMDEYVRNTTARA FAVVASALGIPSLLPFLKAVCRSKKSWQARHTGIKIVQQIAILMGCAILPHLKNLVEIIE HGLVDEQQKVRTITALALAALAEAATPYGIESFDSVLKPLWRGIRQHRGKGLAAFLKAIG YLIPLMDAEYANYYTREVMLILIREFQSPDEEMKKIVLKVVKQCCATDGVEPQYIKEEIL PPFFKHFWNQRMAMDRRNYRQLVDTTVEIANKVGAAEIISRVVDDLKDESEQYRKMVMET IEKIMGNLGSADIDSRLEEQLIDGILYAFQEQTNEDVVMLNGFGTVVNALGKRVKPYLPQ ICGTILWRLNNKSAKVRQQAADLIARIAVVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLG SILGALKSIVNVIGMTKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGAEFVS AREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVC TTVAIAIVAETCSPFTVLPALMNEYRVPELNVQNGVLKSLSFMFEYIGEMGKDYIYAVTP LLEDALMDRDLVHRQTAMAAIQHMSLGVFGFGCEDALNHLLNYVWPNIFETSPHVVQAFM GAVEGLRVGIGPSKILQYTLQGLFHPARKVRDVYWKVYNTVYIGAQDAMIPSYPRIQADE KNTYIRTELDYVLDDFMCDDEEYDLEYSEDSNSEPDVDLENQYYNSKAQKEEDPKAALES FQKVLELEGKDKGEWGFKALKQMIKINFKLGNFGEMMNRYKQLLLYIKSAVTRNYSEKSI NSILDYISTSKQMDLLQNFYETTLEALKEAKNDRLWFKTNTKLGKLYFDREEFVKLQKIL KQLHQSCQTDEGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPL IMGVIRECGGKMHLREGEYEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGIN PFDSQEAKPYKNDPEILAMTNLVSAYQNNDINEFEQILKTNRKNIMEDPFIREHIEDLLR NIRTQVLIKLIKPYTRIHIPFISKELNIDVTEVENLLVSCILDNTILGRIDQVNQVLELH TGAARYSALDKWTHQLLSLHQSVVNKVA-------------------------------- --DVEHSHVRFLGNLVLNLWDCGGQEAFMENYFASQRDNIFRNVEVLIYVFDVESRELEK DMHYYQSCLEAILQNSPDAKVFCLVHKMDL------------------------------ --------------------------------------------FLVISHNQRKPHRDLH RFEKISNIIKQFKLSCSKLAASFHSMEVRNSSFAAFIDIFTSNTYVMVIMSDPNIPSAAT LINIRNARKHFEKLERVD-VLSFSCRLFSVLRFESVIHEFDPYFNYRTTRFLAEEGFYNF HNWFDDRAWYPLGRIIGGTIYPGLMVTSAVFYHVLHFLNITIDIRNMCVFLAPFFSSLTT IITFILTKELKDTGSGLVAAAMISVVPGYISRSVAGSYDNEGIAIFCMLFTYATWIKSVK TGSVFWSSICALAYFYMVSSWGGYVFLINLIPLHVLALMATGRFSHRIYVSYCTVYCLGT ILSMQISFVGFQPVQSSEHMAALGVFGLCQVHTFVDYVRSRLSREQFEILFRSVILFAGV VVATAAGKIAPWTGRFYSLLDPSYAKNNIPIIASVSEHQPTTWSSFYFDLQILTFLFPAG LYFCFKKLTDANIFIILYGITSIYFAGVMVRLMLVLAPVMCILSGIAISSTLNTYMRNLD SKKKADANYPLKNEVATGVIMLVTGFLITYTFHCTWVTSEAYSSPSIVLSARAGDGGRII FDDFREAYYWLRHNTPEDAKVMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMAS TEDKAYEIMRELDVDYVLVIFGGLTGYSSDDINKFLWMVRIGGSTDRGAHIKEKDYYTPQ GEFRIDKEGSPILLNCLMYKMCYYRFGSMYTETGKPTGYDRVRNTEIGIKDFELDVLEEA YTTEHWLVRIYKVKDLENRGN--------------------------------------- ------------------------------------------------------------ ----ENYSLQDEEDSRHGQIGRLWISEGRYKIEVNRVPAGNWVLIEGVDQPIVKTATITE STGNTEAHIFRPLKFNTSSVIKIAVEPVNPSELPKMLDGLRKVNKSYPLITTKVEESGEH VVLGTGELYLDCVMHDLRKMYSEIDIKVADPVVAFCETVVETSSLKCFAETPNKKNKITM IAEPLEKGLAEDIENEVVQITWPRKRLGEFFQNKYDWDLLAARSIWAFGPDSTGPNILVD DTLPSEVDKGLLGSVKDSIVQGFQWGTREGPLCDEPIRNVKFKILDAVIAQEPIHRGGGQ IIPTARRVAYSAFLMATPRLMEPYHFVEVQAPADCVSAVYTVLARRRGHVTQDAPIPGSP LYVIKAFLPAIDSFGFETDLRTHTQGQAFCLSVFHHWQIVPGDPLDKSIVIRPLEPQPAT HLAREFMIKTRRRKGLSEDVSINKFFDDPMLLELAKQDVMLSYPMQETFSLFDNRGDGKI YAYQLGEVLRALGQNPTEAEVKKCNDQDFRISFEMFLPILQTVSKNRGKATLEDFVEGLR VFDKEQNGTISSAELRHLLTTLGERLSDEEVEQLLAGQEDAQGNVVYEDFVKAVMSG--- ------------------------------------------------------------ --------------------------------------------------LHQRAISELI PKCHPLGSFEQMEAIHIASTPAELYNAVLVDTPLAAYFIDCISEQDLDEMNIEIIRNTLY KAYLEDFYNFCQELGGATAEVMCEALAFEADRRAFIITINSFGTELTKDDRAKLYPRCGK LEPDGLAALARADDYEQVKAVAEYYAEYRMLFEGAGNNPGEKTLEDKFFEHEVQLMVYAF LQQFHFGVFYSYVKLKEQECRNIIWIAECVAQRHRAKIDSYIPIFSPRKAVRKISKIPFK VLDAPELQDDFYLNLVDWSSQNVLSVGLGTCVYLWSACTSQVTRLCDLSCDGDSVTSVSW SERGQLVAVGTHKGFVQIWDVTANKRVSVLEGHSARVGALAWNADVLSSGSRDRLILQRD VRTPSVAPERRLTGHRQEVCGLKWSPDHQHLASGGNDNKLFVWNMTSVSPVQTYTEHLAA VKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCVDTGSQVCNLAWSKHSNELVST HGYSQNQILVWKYPSLVQIAKLTGHSFRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTR STKESKSVLNMFTSIR------LYYCLTGQGHRVDFGWFLEETSPFMWGNIGVGLCISLS VVGAAWGIYTTGSSILGGGVKAPRIRTKNLVSIIFCEAVAIYGIIMAIVISQVANYFAGY AMFASGLTVGLSNLFCGICVGIVGSGAALADAQNSGLFVKILIIEIFGSAIGLFGVIVGI LMTTHAKMGSK-------------IIDESNILQWTGLIVPEVAPYNKAAFKIRIDFPAEY PFKPPKITFQTKIYHPNIDEKGQVCLPIISAENWKPATRTDQVIQSLVTLVNYPEPEHPL RADLAEEYSKDKKKFNKNAEEYTKKYGERRPADGASKVYPMQCSALRKNGFVMIKNRPCK IVEMSTSKTGKHGHAKVHLVGIDIFTGKKLEDICPSTHNMDVPNVNRQEYQVICFV-GYF HLMDDQGETREDLKVTATVWKACEEEVVKELK---------------------------- ------------------------------------------------------------ -------------------------------RIQIFKKGGEFVSCIEMNAPRGVAITSDG FVIVADRDNHCIKKYKYLMAAGPIAERNQDATVYVGGLDEKVSEAILWELFLQAGPVVNV HMPKDRITQTHQGYGFVEFMGEEDADYAIKIMNMIKLYGKPIRVNKASAHQKNLDVGANI FIGNLDPEVDEKMLYDIFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFEASDAGIESM NGQYLCNRPISISYAFKKDSKGERHGTPAERLLAAQNPLSQADRPHQLFADAPAPPQPPP VAPPPPPPVGMGMGVLPPGHPGSGAPPPPMPPPGAMPPPG---PPPPPAA-PPPPSSEYP ATPPPPPGMPPPPQGGPPPGKAEAKKVVNPLFEKRPKNFGIGQDIQPTRDLSRFVLWPKY IRLQRQKTILLQRLKVPPPINQFTQTLDRQTATQLFRLMDKYRPESKQEKKARLMGRAEQ RAKGKPDQPTKRP----------------------------------------------- -----------KTATCLAFTNVNPEDRTALSKVTDAVKTNFNERVDEIRRHWGGGIMGSK SLAAIAKLEKAKAKELAHKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-VIDKIHAR QIFDSRGNPTVEVDLYTAKGMFRAAVPSGASTGIYEALELRDKVKGEYHGKGVGKAVDNV NNHLAPALVLDITDQTAMDKLMLDLDGTDNKSKFGANAILGVSLAICKAAAAEKGVPLYR HIADLAGNAEVILPVPALNVINGGSHAGNKLAMQEFMILPTGASSFSEAMRMGSETYHHL KAVIKAKYGQDACNVGDEGGFAPNILNNFEGLDLLVEAIDKAGYTGKIKIGMDVAASEFC KKYDLDFKNPNSNPAEWLSSDKLFEVYEQFIAKYPVVTIEDAFDQDDWDAWTKMNAIQLV GDDLLVTNPKRVQEGIDRKACNCLLLKVNQIGSVTESIQACKMSQSNGWGVMVSHRSGET EDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELGDKAKFAGEHFRNPGAPPS AGAFKKRNTLPTSFRKFYERGDFPIALEHDTKGNKIAWKVEIEKLDYHHYLPLFFDGLCE TQHPYEFFARQGVHDMLEHGGSKILPVIPQLIIPIKSALNTRDSQVMCTTLKVLQHLVVS ADMVGEALVPYYRQILPVLNLFKNKN---------------------------------- -----------------------------------VVIEKDTKVPNATIFTINKEDHTLG NILRVQLHKDPQVLFAGYKNPHPLEHKVVLRIQTTADYSPQEAFTNAITDLISEVSLLEE RFKEAIREKQEGDDDHRRKWDTEEYERLARERLEAELGKKEPPIKRELLKPREYKVDLDS KLGKSQVITKTTPAAQQGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSSLD MVKKRFEMNRKKQEEKK------------------------------------------- --------------MGCTMSAEDRAAMERSKQIEKNLKEDGIQAAKDIKLLLLGAGESGK STIVKQMKIIHEGGFTNEDNKQYKPVVYSNTIQSLVAIIRAMGTLNIAFGDADRESDAKM VLDVIARMEDTEPFSEELLAAMKRLWTDSGVQECFGRSNE-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------------HS QFLNPQQVVGNMALLPLRTNFKGPAFDIIDEAIHFFKANVFFRNYEIKSEADRTLIYVTL YITECLKKLQKCQSKNQGLKEMHSLAISRFYIPGEGSFPLNALYSRPASRQDEDSMRAYI QQIRQETGIRMCDKVFDPTTDKPSKWWMCFVKRKFMDKSLSGPGQAGPYNYSYIFKYIII GDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVAGQKIKLQIWDTAGQERFRAVT RSYYRGAAGALMVYDITRRSTYNHLSAWLTDARNLTNPNTVIFLIGNKCDLEAQRDVTYE EAKQFAEENGLMFLECSAKTGENVEEAFLDTARKIYQNIQDGSLDLNAAESGVQHKPSTP RNTLNTDQT-TREGCSCMTVKAVCVLKDPAIAGTINFTQGE-VIVSGEISGLKPGKHGFH VHEFGDNTNGCISAGAHFNPHGKTHGGPEDTVRHVGDLGNVVAGKFEIKDSQVSLTGEHS VIGRTMVIHGDEDDLGKGGHELSPTTGNAGCRLACGVIGISK------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------VKNCDPKGPLMMYVSKMVPTNDKGRFYAFGRVFSG IVATGQKVRIMGPNYVPLKSIQRTILMMGRYVESIEDVPCGNICGLVGVDQFLVKTGTIS THEQAHNMKVMKFSVSPVVRVAVECSNPADLPKLVEGLKRLSKSDPMVQCIIEESGEHII AGAGELHLEICLKDLEEDHAGIPLKKSPPVVSYRETVTEESNRMCLSKSPNKHNRLFMRA APLPDGLSEDIENGDVTPRQEVKERARYLADKYEMDVTEVRKIWCFGPDGTGANLVIDCS KGVQYLNEIKDSVVAGFQWACKEGVMAEENMRGVRFNIHDVALHADAIHRGGGQIIPTTR RVLYACTLTAEPRLMEPVYLVEIQCPETGVGGIYGVLNRRRGHVFEEAQVVGTPMFLVKA YLPVNESFGFTADLRSNTGGQ--------------------------------------M LPLSLLRTAVNHPMLVELKNGETYNGHLVSCDNWMNVNLREVICTSRDGDRFWRMPECYI RGSTIKYLRIPDEVIDMVKEDVMQKSKGRADPKRGGRGGPGRGGFGVRGG-GRGGPRGGG G----------------------------------------------------------- ------------------------------------------------------------ -------------------------------------------------------SLKYQ TRCIRCFPNKQGYVLSSIEGRVAVEYLDPSPDVQKKKYAFKCHRLKEGGVEKIYPVNAIS FHALHNTFATGGSDGFVNIWDGFNKKRLCQFHRYPTSISSLCFSYDGSLLAIASSYMFEC DPPEDAVYIRKVSDQETKPKMDFQNRAGGKTGTGGVASASETNRDRRERLRQLALETIDI NKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQANLARRAAKEAKEAPAQPAPE KARVDIKKFVKIGRPGYKVTKQRDADNGQQSLLFQIDYPEIVETVCPRHRFMAAYEQKVE PPDKKWQYLLFAAEPYETIAFKVPSREVDKDPKRFWTHWNKETKQFFLQFAFKVESK-SL PPPPRPMPPPPRMDDEQETHNLWRIRKTVMQLCHDRGYLVTQDELDQTLEQFKAQFGEKP SERRPSRNDLIVLVAHNDDPTDQMFVFFPEEPKVGIKTIKTYCQRMQEENIHRALIVVQA GMTPSAKQSLVDMAPKYILEQFLESELLVNITEHMLVPEHVLMTPEEKKELLERYKLKES QLPRIQVGDPVARYFGLKRGQVVKIVRPSETAGRYITYRMVVDKKDSVGTVIGIDLGTTY SCVGVYKNGRVEIIANDQGNRITPSYVAFTSEGERLIGDAAKNQLTSNPENTIFDAKRLI GRFWSEPTVQNDMKLFPFKVINKNNRPHVEVQVGAETRVFAPEEISAMVLTKMKETAEAY LGKTVTHAVVTVPAYFNDAQRQATKDAGNIAGLTVMRIINEPTAAAIAYGLDKRDGEKNI LVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRK NNRAVQKLRREVEKAKRTLSSQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMK PVQKVMEDSDLAKTDIDEIVLVGGSTRIPKVQQLVKELFNGKEPNRGINPDEAVAYGAAV QAGVLSGEEETGDLVLLDVNPLTMGIETVGGVMTKLISRNTVIPTKKSQIFSTASDNQPT VTIQVFEGERPMTKDNHLLGKFDLTGIPPSPRGVPQIEVTFEIDVNGILKVSAEDKGTGN KEKIVINNDQNRLSPEDIERMINDAEKFADEDKKIKERVESRNELESYAYSLKNQIGDKE KLGGKLSDEDKEKIEAAVDEQIKWLEANQEADSEEFKTHKKELEEIVQPIMSKLYEGAPP PQEEEDHDELDDGNDDPELEAIKARVREMEEEAEKLKEMQSEVEKQMSLEEKMDADTRSV YVGNVDYGATAEELEAHFHGCGSINRVTILCDKFTGHPKGFSYIEFADKDSVTTAQALDE SLFRGRQIKVTPKRTNRPGLTTTNRPPRGRGWRPRSL-YYYGYTPQPRRGGRFRPRRAAW YSPYVCHATLLECSQKGSFQSLIEAVKAEKEKKARLQETIQKEEEGRKRVKMLQKMLTDV KKEKETELQQRAEMIAHLKDQLQEMKAKTNMEGKYIKKSAEVSVAQTQKRCNMSEKEARD EIEMLRKKVDEETRVNQEIEQYLGKHQTELEQKVEYWMEKYDKDVDEKQHELDVLKQSKA KDLERLQDLTKLYAEYEQVVVEDRIEKEKARRKAEMEAEELKAAIKVQSWFRGVMVRRGL GPYGKKKKKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNEDLATAILRRKARPNRLVVEEAINEDNS VVSLSQAKMDELQLFRGDTVLLKGKRRKETICIVLSDDTVSNDKIRINRCVRNNLRVRLG DIVSIQACPDVKYGKRVHVLPIDDTVEGLTGNIFEVYLKPYFLEAYRPVRKDDIFLVRGG MRAVEFKVIETDPSPYCIVAPDTVIHCEGEPVKREEEEEALNDVGYDDIGGVRKQLAQIK EMVELPLRHPQLFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSK LAGESESNLRKAFEEAEKNSPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQ RSHVIVMAATNRPNSIDAALRRFGRFDREVDIGIPDATGRLEILRIHTKNMKLADDVDLE QIAAETHGHVGADLAALCSEAALQQIRGKMDLIDLEDESIDAEVLDSLAVTQEDFRWALS KSNPSALRETAVEVPNVTWEDVGGLENVKKELQELVQYPVEHPDKFLKFGMTPSKGVLFY GPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFD ELDSIAKARGGNVGDGGGAADRVINQLLTEMDGMSSKKNVFIIGATNRPDIIDPAILRPG RLDQLIYIPLPDDKSRIQILKASLRKSPISKDVDLDFLAKTTHGFSGADLTEICQRACKL AIRDCIEAEIRRERERADNPDDYDPVPEIRRDHFEESMKFARRSVTDNDIRKYEMFAQTL QQSRGFGGGASSSFGGTSVFGGNAFNNPKRDIEVTSPPDDTVSSLAFSPGVLPSTFLIAG SWDNNVRCWEVQQNGHTIPKAQQTHTGPVLDVCWSDDGTKAFTASCDKTAKMWDLNSNQT VQAAQHDAPIKTVNWIKAPNYSCLMTGSWDKTLKFWDTRTPNPMLTIQLNERAYCADVLY PMAVVGTAGRGLIIYQLENQPQEFKRMESPLKYQHRCVSIFTDRKTNAPTGFALGSIEGR VAIHYVNPVNPKDNFTFKCHRGGMQDIYAVNDIAFHPIHGTLATVGSDNRFSFWDKDART KLKTSDQFDQPITHCNFNAQGTIFAYASGYDWSKGHEGFDPQKMKPHIYLRSCYDELKPS QKKMSSPSPGKRRMDTDVVKLIESKHEVTILGGLNEFIVKFYGPQGTPYEGGVWKVRVDL PDKYPFKSPSIGFMNRIFHPNIDEVSGTVCLDVINQAWTALYDLSNIFESFLPQLLTYPN PIDPLNGDAAAMYLHKPEEYKKKVRDYVSKYATEEALREAESSMSDFSEDEAQDMEL--- -DVLTTLKILIIGESGVGKSSLLLRFTDDIFDQEQAATIGVDFKVKTLTVDGNRAKLAIW DTAGQERFRTLTPSYYRGAQGVILVYDVCSKSSFNKLDAWLNELETFATKQDIVKMLVGN KIDMENREVSREEGLKFARKHHMLFIEASAKTKEGVQCAFEELVEKVIQTPGLWETDGLS LGSVIWSIINGSFCSFKVWTKAQKFCRNEYNLTGLCNRSSCPLANSQYATVREEKGVCYL YMKTIERAAFPARLWEKVKLSRNYEKALQQINESLIHWPRYLIHKCKQRFTKITQYLIRM RKLQLKRQKKLVPISKKIERREKRREEKALVAAQLDNAIEKELLDRLRKGTYGDIYNFPQ HAFDKALEQEEVEEEEESEAEVEYVAEDEFEESDISDLEFIQGRFQAAPNMKTFEVYRFN PDVPGDKPRMQQYEVDLNKCGPMVLDALIKIKNEIDPTLTFRRSCREGICGSCAMCINGL NNLACLAKIDDG-KKKMKIHPLPHMYVVKDLVPDMNNFYAQYKFIEPYLKKKDEKESDIG KQAHFQS-----------ECILCACCSTSCPSYWWNSDKYLGPAVIMQAYRWIMDSRDDF RQERLEVMKDKWSMYRCHTIMNCTKVCPKGLNPGAAIAEVKKLLVGMDSPGIP--DIRPN YTIYINNLNEKIKKDELKKSLYAIFSQFGQILDIVAMKSLKMRGQAFVIFKEINSATNAL RSMQGFPFYDKPMRISYSKKDSDVIAKMKGTFVERPKKRRQDEGKRKKKQSAPTSIPEQP PHHILFLTNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENEVQSGAAKVALQ GFKITPTNAMKISFAKKMDSEGRKVVICDNGTGFVKCGFAGTNFPTHIFPSLVGRPILRS NTKVGDIEIKDLMVGDEASQLRSMLEVNYPMENGIVRSWEDMIHLYDYTFGPQKLDVNPA DCKLLLTEPPMNPTKNREKMIEVMFEHYQFHGLYIAIQAVLTLYAQGLLTGVVVDSGDGV THICPVYDGFALPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRIMKEKLCYV GYDVEQEQKLALETTVLVESYTLPDGRVIKVGGERFEAPEALFQPHLINLESIGIAELLF NTIQQADIDTRSEFYKHIVLSGGSTMYPGLP----------------------------- -------------------------------------------------MADTVGKPIEC RAAVAWAAKQPLSIETITVAPPKAGEVRIKVLATGVCHTDAYTLDGFDPEGKFPVVLGHE GGGIVESVGEGVTSVKQGDHVIPLYVPQCRECKFCKHPKTNLCQKIRVTQGNGVMPDGTS RFTCKGKELAHFMGCSTFSEYTVVSEISLCKVDEKAPLDKVCLLGCGISTGYGAALNTAK VEQGSTCAVWGVGAVGLAVIMGCKKAGASRIIGIDINPDKFEVAKKFGATECVNPKDHDK PIQEVLVAMTDGGLDYTFECIGNVGTMRAALESCHKGWGVSTIIGVAAAGQEISTRPFQL VTGRVWKGTAFGGYKSRDSVPKLVDSYMAKDLMVDEFVTHNMPLEEVNKAFDLMHEGKSM ESYDVIANQPVVIDNGSGVIKAGFAGDQVPKYHFPNYIGRPKHVRVMAGALEGDMFIGPK AEEHRGLLAVRYPMEHGIVRDWNDMERIWQYIYSKDQLQTFAEEHPVLLTEAPLNPRRNR EKAAEIFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVSHAVPIYEGFAMPHSIM RVDIAGRDVTRYLQLLLRKEGQNFHTSAELEIVKTIKERACYLSINPQKEETMETEKTQY TLPDGSTLEIGPARFRAPELLFRPDLIGDECEGIHEVLAYAIQKSDMDLRRVLFSNIVLS GGSTLFKGFGDRLLSEVKKLAPKDIKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKR EYEEEGVRAVHRKTF----VEKVVVHPLVLLSVVDHFNRMGKVGNVKRVVGVLLGSNRQG VLDVSNSFAVPFDEDEKDRTVWFMDHDYLEHMYTMFKKVNAREKIVGWYHTGPKLHPNDI AINELMRRYNPNSVLVIIDAKPKDLGLPTEAYIAVEEVHDDGTPTSKTFQHVPSEIGAEE AEEVGVEHLLRDIKDTTVGTLSQRITNQLMGIKGLHLQLQDIHAYLEKVVSGKLPINHQI VYQLQDIFNLLPDVNLQEYVKAVYVKTNDQMLVVYLASLIRSIIALHNLINNKIQNRDAE KNEGKDKT----------------------------KTTILYQFLMNEVVHTSPTIGSNV EEVVWKNIHFLMWDIGGQDSLRSAWATYYTNAEFIILVIDSTDRERLSITKEELYKMLAN EDLRKA------------------------------------------------------ --------IPTRRVLVSDPTQMPSDYSQTPGGTLFSTTPGGTRIIYDRQFLMQCRNSPLA KSPP-NLPKIPGVTSP-------------------------------------------- ------------------------------------------------------------ ----NKNSDFCAPLTSFDWNEVDPNLIGTSSIDTTCTIWGLETGQVLGMVSGHVKTQLIA HDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHALLRLAWNKQ DPNYLATMAMDAMEVIILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQAL IWDIQQMPRAIEDPILAYTAAGEINQIQWSSTQPDWISISYNNCLEILRVRNFSVSSRVA VLGAAGGIGQPMSLLLKLNPAITQLALYDIVNTPGVAADLSHISTRAHVSAYQGPEQLAG CLKGCEVVVIPAGVPRKPGMTRDDLFNTNASIVANLAEAAAEHCPKAMLCIISNPVNSTV PIASEVYKKKGVYDPARIFGVTTLDIVRAQTFIAEGKGLDVNQVNCPVIGGHSGVTIVPL ISQCTPPVSYPEEERVKLTERIQNAGTEVVEAKAGTGSATLSMAMAGARFVDSVLSAVHG VEGIVECSYVRSDETEAKYFSTPVLLGKTGVQKNLGMGKLLEFEANLVKAAMPELLSNIK KGEDFVNK---------IKTRIITDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFAS TLSHLRRLNSPIGRDGKLARPRQLHNTLWGMICPAETPEGGAVGLVKNLALMAYISVGSQ PSPILEFLEEWSMENLEEISPAAIADSTKIFVNGCWVGIHKDPEQLMNTLKKLRRQMDII VSEVSMIRDIREREIRIYTDAGRICRPLLIVENQKLLLKKRHIDLLKEREYNSYSWQDLV ASGVVEYIDTLEEEVIMVAMNPDDLQEKGVGYCSTYTHCEIHPSMVLGVCASIIPFPDHN QSPRNTYQSAMGKQAMGVYITNYHVRMDTLANVLFYPQKPLVTTRSMEYLKFRELPAGIN AIVAIASYTGYNQEDSVILNESAIDRGLFRSVFYRSYKDQESKRGLDIEEIFEKPDKMFV QGMRPAVYDKLDEDGIIAPGTRVSGDDVLLGKTMTLPDTEDELEGTTKRFGKKDASVFMR RSETGIVDQVMVTINQDGYKFVKIRVRTVKTPQIGDKFASRHGQKGTCGIRYRQEDMPFT VEGLTPDIIVNPHAIPSRMTIGHLIECLQGKVSANKGEIGDA-PFNDTVNVRKISSLLQE YGYQLRGNEVLMNGHTGRKLNAQVFLGPTYYQRLKHMVDDKIHSRARGPLQILNRQPMEG RSRDGGLRFGEMERDCQIAHGAAQFLRERLFEVSDPYRVHVCNICGLIAIANLRNNTFEC KGCKNKTQISQVRMPYACKLLFQELMSMSIAPRMMVICVEAQGGFSFENCKRNAILATGF KAPTATKTGTTIVGIVFKDGVVLGADTRATEDTIVADKNCSKIHYIAPNVYCCGAGTAAD TEMTTQMISSQLELHRLNTGRVPRVCTANRMLKQMLFRYQGYISAALVLGGVDSTGPHLY SVYPHGSTDKLPYVTMGSGSLAAMAVFESGFKPEMEKEDAMKLVRDAIAAGIFNDLGSGS NVDLCVITKKVDYIRPYDEANQKGVRQGNYRYKPGTTAVLTTQVKKLEVELFMSKVSFKI TLTSDPKLPFKVLSVPEATPFTAVLKFAAEEFKVPAATSAIITNDGIGINPAQSAGNVFL KHGSELRLIPRDRVGNMAFTFAAFCYILALILSAFLIFFVIYHIIAFDELKTDYKNPIDQ CNSLNPLVLPEYGLHLLYNILFLFAWQWGTLLLNMPLILYHIHRYMHRPVMSGPGLYDPT TIMNADQLSRAQKEGWIKLAFYLLSFFYYLYSMIYVLVSSMGLLTILKKLKEKEKQVRIL MLGLDNAGKTTILKKFNGEDINTISPTLGFNIKTLEHRGFQLNVWDIGGQKSLRSYWRNY FESTDGLIWVVDCADRRRLEDCKQELDALLLEERLSGATLLVFANKQDLPGALSPEEIRE ALELDNIKTHHWLIQGCSAVTGENLLKGIDWLIDDIASRIFTLDHSKRKVCYYYDGDIGN YYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATQEEMTKFHSDDYIKFLRSIRP DNMSEYNKQMQRFNVGEDCPVFDGLYEFCQLSTGGSVASAVKLNKQATDLAINWAGGLHH AKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY GEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEHIFQPVICKVMEMYQPSAVVLQC GADSLSGDRLGCFNLTLKGHGKCVEFMKKYNLPLLMLGGGGYTIRNVARCWTYETSLALG TDIANELPYNDYFEYYGPDFKLHISPSNMANQNTPEYLDKIRTRLFENLRMLPHAPGVQM QDIPEDALNDEANPDERISIRASDKRIACDEEFEDSEDEGDGRPRHRENYNKQHRENRSF ECNICLDTAKDAVVSMCGHLFCWPCLHQWLETRPQRQVCPVCKAGISREKVIPLYGRGSS T-QDPRDKMPPRPPGQRSEPENTAGFPGFGFGFQMSFGIGAFPFGF-------------- --------------------------------QYALTHKQEQAHEDSIWACAWAKSEKDG TENVITGSIDDTVKIWRWMDLELKHTLEGHALGVVSVDTNVQGTMAASSSLDAHIRLWDL ETGKQVKSIDAGPVDAWTICFSPDSRYLASGSNTGKINLFGVETGKKESQLDTRGKFTLS LSISPDGKYIACGAIDGIINIFDMTTGKLLEGHAMPIRGLCFSPDSQLLVTASDDCSIKI YDVQHANLAGTLSGHGSWVLNVAFCPDNTHFVSCSSDKTVKVWDAGTRQCIHTFYDHVDQ VWSSCYNQSGSKIVSVSDDRAIHIYDCPVETDDAFDNRFEKFLNRQDIDSWELRKAMNDL TGMDLVPEPKIIIAALKACRRINDYALAVRYLESVKDKCGPRVDDIWPYIEGQLQPTLQE LGILTPEQMGYDKPELALKDVYDMVVRVRGLPWSASHDEVLNFFEGVNIVNGKGGIHFTF VRDGRPSGEAYIEMENEEDVEKALKKDKQHMGKRYIEVFRSKRSEMDWVVKRSGPNQDAV VRLRGLPFGCSKEEIAHFFTGLELVPNGITLLHDHQGRTTGDAYVQFATQDLAEKAQLKH KEKIGHRYIEIFKSSLAEVRNSYESQTGHCVHMRGLPFQASEQDILEFFKPLNPVNVVIH YNNGRASGEADVDFATHEEAQQGMTKDRASMKHRYIELFYKDKDKPTQIRYSNIQAAKAI SDAIRTSLGPRGMDKMIQSSNGDVTITNDGATILKEMQVFHPSAKMLVELSKAQDVEAGD GTTTVVVVAGSLLDAAQKLLYKGIHPTTISESFQKCAAKSVEILEEMSTPLELSDRDSLL QSATTSLNSKVVSQYSSILSPLCVDAVMKVIDPATSTSCDLRDIKVVKKLGGTVEDTELV DGLVLNQRAAGAGGPSKVEKAKIGLIQFCISPPKTDMENQVVVSDYTQMDRVLKEERAYI LNIVKQIKKAGCTCLLIQKSILRDAVSDLALHFLAKMKIMVIKDVEREEIEFICKSLSCK PVASLDHFTVDMMGTAELVEEVQCGSSKVVKITGIANQGKTVSVLVRGSNKLVLEEADRS IHDALCVIRCLVKKRALIAGGGAPEIELALRLNEYSQTLSGMEQYCFRGFAEALEVVPFT LSENAGLNPISTVTELRNRHAKGEKTAGINVRKGAITNILEENVVQPLLVSTSAISLAAE TVRSILKIDDIVNCM--------------------------------------------- --------------------------------------ITTPEDGYNVSLLYSDGVPTDY KDVVKKAGLLKRNCFASVFEKYFEFQEEHKRAVVHYRDDETMYVDARKDRVTVIFSTVFK DNDDIVIGKVFMQEFKEGRRMYQQAPQVLFSHKEPPMELSNTDAKVGDNIGYITFVLFPR HEARDNTINLIHTLRDYLHYHIKCSKAYIHSRMRAKTSDFLKVLNRARPEVKNTEKKTIM LMFCPICANVLVVEEGPKCYRFACNTCPYIYNVTRKITNRKYPKLKEVDDVLGGAAAWEN VDSTEETCPKCSHSRAFFMQIQTRSADEPMTTFYKCCDADCGHRWR-------------- ------------------------------------------------------------ ------------------------------------VEGCLIAGSAMGARAAYIYIRGEF YNEASNMNVAIKEAYAAGLLGKNACGSGYDFDVYLHRGAGAYICGEETSLIESLEGKAGK PRLKPPFPADVGAFGCPTTVNNVETIAVAP------------------------------ ------------------------------------------------------------ -----------------------------------------------------FTQEQVD EVNQQLNQTRSQRVRAAMFPETLEEGIQIPSTQIHPDQPTAVQRLAEPSQMLKHAVVNLI NYQDDADLATRAIPELTKLLNDEDQVVVSQAAMMVHQLSKKEASRHAIMNSPQMVAALVR AMTNTNDIETTRCAAGTLHNLSHHRQGLLAIFKSGGIPALVKLLSSPMESVLFYAITTLH NLLLHQEGSKMAVRLAGGLQKMVALLQRNNVKFLAITTDCLQILAYGNQESKLIILASGG PGELVRIMRSYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALAMHLGHQSTRLVQN CLWTLRNLSDAATRAEGMETLLQMLVQLLSSNDINIVTCAAGILSNLTCNNQRNKVLVCQ VGGIEALVRTILQAGDREDITEPAVCALRHLTSRHPEAEMAQNAVRLHYGLPVLVKLLHP PSRWPLIKAVVGLIRNLALCPANHAPLREHGAIPRIVQLLIRAHQDTQRQQGAYVDGVRM EEIVEGTVGALHILAREAHNRAVIRGLNCIPLFVQLLYSPIENIQRVAAGVLCELAADKE GAEVIEQEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRGD QMSADLQWMIIRNNSSYLLKGSTFSREANNLKSKNSFRYNGLVHKKTIGVEAAADGKGLV LVTKKNWRKPSKNYTRTELKRGSRRTLSTLRKVIRNNRYRKDLKMAALRRASALLKSQRE PVLVKTRDEPYYCSQQINIPPELPDVLKQFTKAAIRTQPKDVLAWSAAYFRAMASGETPP VKERLEMPVATQKTDTGLTPGLLRVLNKQLGPKKKVPLSLVEEKWKDIALPKEQFDELVR IGAFSGEVEWLKFFALACSALGDNITTSMKIVCEILTADPQGGPARIPFQLFKDLYNYLA QIDGEISQDHINDVISHLQYSVDKQDGFVQPRNFLGADCPSL--RTDSVQKEQVMEQVKA QIAVANAQELLQKMSDKCFTKCITKPGSSLDNSEQKCIAMCMDRYMDAWNLVSRTYSTRL QKERN--MNRLFGRAKPKGPAPNLTDCIAGIDSRGDSIDKKIGKLDAELGKYRDQMKKMR DGPSKNMVKQKALRVLKQKRMYENQRDQLMQQSFNMEQSNYAIQTLKDTKTSVDAMKVGV KQFKKEYKNVNIDQIEDLQDQLEDMTEQAGEIQEIMGRSYGMPEIDDDELEAELDALGDD LAFDEDTSYLDEV-AAPNAPTGVPGADSVTNKDGVLVDEFGLPQIPA-MTPRTPATPASP QLQNIVCTVNLACKLDLKRIALHARNAEYNPKRFAAVIMRIRDPRTTALIFSSGKMVCTG AKSEDQARLAARKYARIVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSY EPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKVRSEIYEAFENIYPILKGFRK-EDDDD EGFVGMEMEPEPSS-KHVEEFIYEVLTTEQIVQHMVDCIKEVNAIVEIPATTTRILLNHF RWDKEKLMECYYDGDQEKLFNEAHVISPYKKALEVTCEICYLIIPTMMAGLECGHRFCTA CWTEYLTTKIMDEGMGQTIACAAHGCDILVDDATVMNLVRDPKVKLKYQHLITNSFVECN RLLRWCPMPDCGHAIRVQYFDNKPVICACGHIFCFSCGENWHDPVKCQWLRKWIKKCDDD SETSNWIAANTKECPKCRATIEKDGGCNHMVCKKCRFDFCWVCLGPWEPHGSSWYNCNRY DEDEAKKARDAQEGSRSALQRYLFYCNRYMNHMKSLKFENKLYSTVKLKMEEMQQHNMSW IEVQFLKKAVDVLCQCRQTLMFTYVFAFYLRKNNQSIIFEDNQKDVENATEQLSEYLERD ITSDMLVDIKQKVQDKYRYCESRRKVLLDHVHEGYEKDLWEYQEMANTDGKLSTTERVVK SVPFPPSHKLTISEVFDPKGKPRPDVLKQHFILEGRVSEDVALRLINEGAALLRQEKTMI DIEAPVTVCGDIHGQFYDLMKLFEVGGPPSSTRYLFLGDYVDRGYFSITERVYDACMEAF DCLPLAALMNQQFLCVHGGLSPEIHTLEDIRKLDRFKEPPAFGPMCDLLWSDPLEDFGNE KTTEHFTHNSVRGCSYFYSYAACCDFLQRNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSL ITMFSAPNYLDVYNNKAAILKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVT EMLVNVLNICSDDELMSEGDDTFE----ARKEIIRNKIRAIGKMARVFQVLREESESVLQ LKGLTPNGLLPIGALSGGKDSLKTALSGFDPSHKISGFNEAKYLDKMNERMPPRK-FSGG RGGFSGFSGGRGG-SRGGFGGGRGSGRGGRGGMRGGRNVVIEPHRHEGVFIARGKEDALI TKNMVPGESVYGEKRMSAEGAMKVEYRAWNPFRSKLAAAILGGVDSIHMKPGAKVLYLGA ASGTTVSHVSDIVGPEGLVYAVEFSHRSGRDLINVAKKRTNIIPIIEDARHPHKYRMLVG MVDTIFADVAQPDQARIVAINAHHFLKNQGHIVISIKANCIDSTAQPEAVFAEEVNKLRK EKIKPKEQITLEPYERDHAVVVGVYRPPPKK----------------------------- ------------------------------------------------------------ ----------------------------PEMYRQLGIDYDDRVLPSIVNEVLKSVVARFN ASQLITQRQQVSLMIRRELTERAHDFNIILDDVAITDLSFSPQYTAAVESKQVAQQEAQR AQFIVEKAKQERQQKVVQAEGEAASALMIGQAISMNPGYLKLRKIRASQNIARTIAVSKN RVYLNAGNLMLSLSDREYDASLESYTGSSSDEEDINPREKEQKNSKGFKQFCVRIEQHAF GRREIEIAEQEMPGLMALRKRAQADSPLKGAKVVGCTHITAQTAVLIETLGALGAHVRWS ACNIYSTQNEVAAALAEAGYSIFAWKGETEDDFWWCIEQCIQSDSWQPNMILDDGGDATH LMLKKYPAVFGLVRGIVEESVTGVHRLYQLSKSGKLTVPAMNVNDSVTKTKFDNLYSCKE SIIDALKRTTDVMFGGKQVVVCGYGEVGKGCCAALKGMGAVCMVTEIDPICALQACMDGF RVVKLSEVIRQVDIVITCTGNKNVVTRDHMDKMKNGTILCNMGHSNTEIDVNSLRTPDLT WERVRSQVDHIIFPDGKRIILLAEGRLVNLSCSSIPSFVVSITGATQALALIELFNAPAG RYKHDVYLLPKKMDEYVASLHLASFDAHLTELLDDQAKYLGLNKAGPFKPNYYRYXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXFVAGGFGGVCVVLSGHPLDTLKVRLQTMPKLYTGALDCAKQIFKNEGPRGF YKGMAAPLIFAVSFFGFNV-GKAIQVAGVFSTTIMAPGERIKCLLQVCAKKLYREGGIRS VYRGTAATLLRDVPASGMYFMTYEWLQIVLTPEGKSRKDMSVRTLFAGGMAGVFNWIVAL PPDVLKSRLQIANEGILALYKGCTPVMIRAFIANGACFVGYEIAMKGLN----------- ------------------------------------------------------------ ----------------------------------------QDVDMDLLQEREQAIRQLES DISDVNQIFTDMAMLVHEQGEVIDSIETNVEKVHVDEGRDQLSKAREYQNKARKKKCICL ILVLIILAIIGIIIGVTVSMVNVMKGILVECDPAMKQFLLHLEETMELGKKFIIQDIDET HLFISTDILDTLQDKIDGLMDKLSFPVGKGKDKAPTPQEAIQRLRETEEMLQKKSDFLEK KVDQELATAKKRAALAALKRKKRYEKQLGQIDGTLSTIEFQREALENASTNTEVLRVMGD AAKALKHAHKNMDVDDVHNLMDDVAEQQEIANEISEAISNPVGFGQDVDDDDLMAELEEL EQEELDKKLLDVEDLPSVPVGDDDEMKELEMWAS-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --GQKRLGQLAKWKTAEEVAALIRSLPVEEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKG SELQLPFQACLKVEKFGDLILKATEPQMVLFNLYDDWLKTISSYTAFSRLILILRALHVN NDRAKIVLKPDKTTVTEPHHIWPTLTDEEWVKVEVQLKDLILADYGKKNNVNVASLTQSE IRDIILGMEISAPSAQRQQIAEIEKQTKEQSQLTATTTRTVNKHGDEIITTTQSNYETAT FASKTEWRVRAISATNLHLRTNHIYVSSDDIKETGYTYILPKNILKKFIIISDLRAQIAG YLYGVSPPDNPQVKEIRCIVMPPQWGTHQTVHLPNLLPQHEYLKEMEPLGWIHTQPNELP QLSPQDVTTHAKVMADNPSWDGEKTVIITCSFTPGSCSLTAYKLTPSGFEWGQKNTDKGN NPKGYLPSHYEKVQMLLSDRFLGFFMTPIHGSWNYNFMGVRHDPNMRYEMQLSNPKEFYH EVHRPSHFLNFAAIEEGADREDLY--YTSTRPNLAIGKNTKVICQGFTGKQGTFQSQQAL EYGTNMVGGVSPGKGGKTHLGLPVFNSVSEARDKTGADATVIYVPPPYAAAAIIDAIDAE MPLIVTITEGIPQHDMVKVKHKLLRQNKSRLIGPNCPGIIKPGECKIGIMPGHIHKPGNI GIVSRSGTLTYEAVHQTTQVGLGQTLCVGIGGDPFNGTNFIDCLEVFINDPATRGIVLIG EIGGQAEEKAAQYLTEHNGPDAKPVASFIAGLTAPPGRRMGHAGAIISGGKGGAQEKIQA LKDAGVHVTMSPAQMGTTILEAMKKAGRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFTRFVELGRVAYIA FGPDEGKLCVITDVLDQNRALVDGPCSGVARKILNFKQLHLTLFTIIGPSARSGSVKKAW EKEDITKKWNESTWAKKIEARKTKLTLTDFDRFKLMKAKQARNRLVNIEFGKLRKGAKKT CPLLLRVFCSNGRHHSLNEYSRGNTPANELQIYTWLDATLKELTSLVKEVNLDARKKGTY FDFSIICPDNRGPTYRMREIGTTCAGRKGVDDGVSLGSKRFIIGDYIDIAITPPRGLGKT LQTISLIGYMKHFRNIPSPHLIIAPKSTLNNWMAEIKRWVPTLRSVCLIGTQEQRAALIR DTLMPGEWDICVSSYEMVIKEKSVFKKFNWRYMVIDEAHRIKNEKSKLSEIVREFKTANR LLLTGTPLQNNLHELWALLNFLLPDVFNSADDFDSWFNTNTCLENDMLVTRLHEVLRPFL LRRIKADVEKSLLPKKETKVYIGLSKMQREWYTKILLKDIDVVNGAGKGDKMRLLNILMQ LRKCSNHPYLFDGAEPGPPYTTDQHLVDNCGKMVLLDKLLPRLQQQDSRVLIFSQMTRML DILEDYCCWKEYDYCRLDGQTPHEERQVSIDEYNKPNSTKFVFMLSTRAGGLGINLATAD VVILYDSDWNPQVDLQAQDRAHRIGQKKQVRVFRFLTENTVEERIVERAEMKLRLDSIVI QQGRLQDQAANKEVLSMIRHGASEVFSSKDSAITDEDIDDLLEKGEEKTAELQKKMEALG ESTLRSFTLDTNEQSVYQFEGQDYREKQKAIGMG-WIEPPKRERKANYAVDAYFREALRV SEPKAPKAPRPPKQPNVQDFQFYPPRLFEILDKEIYYYRKTIGYRVPRNPDLGSDAERVR KEEQKKIDESDTLNDEEMQEKEDLLKGFINWSKRDFQQFIKANEKFGRDDIESISKDVEG KTPEEVMEYSSVFWERCHELQDIERIMAQIERGEAKIQRRISIKKALDAKMARYRAPFHQ LRIQYGTNKGKNYTEEEDRYLVCMLHKLGFDRENVYDELRAAVRQAPQFRFDWFIKSRTA MELQRRCNTLITLIERENLELEEREKAERKKDSKPSWAEQVELGEDVELPPIQEDFNEDS NIKTITEYKYNDDGKKVKVIKTYRVETKKMFKNVARRKTWKKFGAAEKDPPGPNPSNTIE EIYMQFVHNKEQDDNNPLNRLKVQCRYCKGDHWSKQCPHKDKLELLQESLVKPGKYVPPS MREGGNKRGESMMNDESATIRVTNLSEDTRESDLQELFRPFGSIQRIYLAKDKVTGQSKG FAFINFHRREDAARAIAGVSGFGYDHLILNVEWAKPS----------------------- ----------------------------------------------------SYYRGAAG ALLVYDITSRETYNALTNWLTDARTLASPNIVILLVGNKKDLEAEREVTFLEASRFAQEN ELMFLETSALTGENVEEAFLKCARSILTKIESGELDPERMGSGIQYGDASLRRLQQKRPE CSCFIQPSSKNKLDTSQWPLLLKNFDKLNIRTGHYTPIPSGCSPLKRTIEEYVKSGFINL DKPANPSSHEVVAWIKRILRVEKTGHSGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYV CIFRLHSAVEDLKKINQAVETLTGALFQRPPLISAVKRQLRVRTIYESKMLEYDEERNMG IIWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGIQSEKDAMVTMHDVLDAQWQYD HTKDENYLRRVIKPLEAMLVSHKRIILKDSAVNAVCYGAKVMLPGVLRYDDGIEINDEIV IVTTKGEAVALAIAQMTTAVIATCDHGFVAKLKRVIMERDLYPRKWGLGPVASRKKAMIK DGTLDKYGKPNPNTPTGWKSSYVDYGATPKRKHETPSTEKKKKKKKKKMAEVGWDRKRQP KASQMRSQAAINAAQRSGGDIETTKKWSAGQNKQHSVDKNTAKLDRETEELSHSKVGLDV GRLIQQGRQAKSFTQKDLATKINEKPQVINEYESGRAIPNQQVLSKLERVLGLKLRGKDK GQPLGPKMLKPKALTQVLGQANTGGVQSSLLLNNEGALLAFSGYGDKDARVTAAIASNIW SAYEKNGQAALNDDKLNLVLMECEEGKVAITRVANLLLCIYAKESVGFGMLKAKVKALAE YLEDPLTKVATSSAATARITAKKQTLDDAYAPPANFLEIDVINSQGKKRYTDYEVRMRTN LPVFKVKESSVRRRYSDFDWLKSELERDSKIVVPPLPGKAWSRQLPFRNDEGIYDDEFIE DRRKGLEQFVNKVAGHPLAQNERCLHMFLLEPVIDKNYVPGKVRTT-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----EETVQLRERHWRIFSLSGTLETVRGRGIIGKEPIFSRSQPAFQYTSHVSLQAPSGH MWGTFKMEREDGSFFECRIPAFSLDSKQEDG-ATSKGANTYNRQNWEDSEFPILCQTCLG DNPYIRMTKEKYGKECKICARPFTVFRWCPGARMRFKKTEVCQTCSKLKNICQTCLLDLE YGLPVQVRDAALKVADEMPKSDVNKEYYTQNMEREIANTDGTVAVGNVGKAQATSDMLLK LARTTPYYKRNRPHICSFWVKGECKRGEECPYRHEKPTDPDDPLADQNIKDRYYGLNDPV AEKLMKRYTNMPKLEPPEDMDVFLMIRRKKTTVFIDAKESTTVLDLKRMVQGITKKSPED MRLFKDNKTLGDYGFTSSTARAQAPATVGMSFREFEPLEIAPLSTPPELPDVMKPQESSS SHPPEHLYRYQAVLLRARFDEHKDEDLVKAKKVLLAGEAELFDKMHPQPMKFPNSPGGVA YGREAKIPDWMLDIWHPLERAQYPEYFAKREQRKLEYIQRWEKVHGKAEMEDYIKIEKIG EGTYGVVYKGRNKRTNRTVALKKIRLESEEEGVPSTAIREISLLKELNHPNIVRLEDVLM QEAKLYLVFEFLSMDLKRYMDSIPSGQYMDKMLVKSYMYQILEGILFCHQRRVLHRDLKP QNLLIDKNGVIKLADFGLARAFGIPVRVYTHEVVTLWYRAPEVLLGNPRYSTPVDIWSIG CIFAEMATKRPLFHGDSEIDQLFRIFRTLTTPTEETWPGVTNLPDYKPIFPRWTNNTLAD SVDSDGLDILQKTLIYDPAARISAKEALTHPYFAARLFNSLGKLGIGLAVAGGVVNTALY NVDGGHRAVIFDRFAGVKQTIIGEGTHFLIPWVQRPIIFDIRTRPRSVPTITGSKDLQNV NITLRILFRPVPDQLPSIYTNLGLDYEERVLPSIVNEVLKATVAQFDASECITQRERVSS TISTELTQRAASFGFILDDIAITHLTFGREFTEAVEMKQVAQQDAERARYVVEKAEQQKL AAIIQAEGDSMAAEQLAKAFGDAGEGLVELRKLEASEDIAYQLSQSPNVVYLPHGQNTLL SLPMKVIQSNQLVKLPEEVTVKVKARKVTVKGPRGTLKKDFSHLAVDIQQRGKNEILVEK WFGIHQELAAVRTVCSHIENMAKGVIKGFRYKMRSVYAHFPINIAISENSTCVDIRNFLG EKYTRQVRMQQGVTCVSSTAQKDELILEGNDIEAVSRSAALIQQSTTVKRKDIRKFLDGI YVSEKGTVVQDMGCAVSTEDRVAAERSKQIDKSLRIDGEKASREVKLLLLGAGESGKSTI VKQMKIIHEQGYSQEECLQYRPVVFSNTIQSMIAIIRAMGQLKIDFGHPERADDARQLFQ LAGSTEDGELTPELAHIMKRLWKDAGVQECFGRSREYQLNDSAEYYLNALDRISQNNYIP TEQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFIVAMSE YDLTLAEDQEMNRMMESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLAICFPE YRGANTYEEAAAYIQLQFNKRRDTKEIYTHFTCATDTNNVQFVFDAVTDVIIKNNLKDCG LFKKFAQMKRMINLKDTRIKKTDRERKKKKKPDPQNMKIRELPQASSALFLQYNTQLGPP YHILVDTNFINFSIKNKLDIVQSMMDCLYAKCIPYITDCVMSELEKLGSKYRVALRIAKD PRFIRLPCMHKGTYADDCLVERVNQHKCYIVATCDKDLKRRIRKVPGVPIMYLQQHRFSI ERMPDAFGAPKMSFSSDEVNFLVYRYLQESGFSHSAYTFGIESHISQSNINGGLVPPAAL LSIIQKGLQYTEAEISIGEDGSERVIESLSLIDAVMPDVVESRKQAAAKNANGEEHTDAM EIDGSLEIPSSKATVLRGHESEVFICAWNPTNDLLASGSGDSTARIWNMNDNSNANQLVL RHCIQKGGTEVPSNKDVTSLDWNCDGTLLATGSYDGFARIWSTDGRLVSTLGQHKGPIFA LKWNKKGNYILSAGVDKTTIIWDASSGHCTQQFAFHSAPALDVDWQTNTSFASCSTDQCI HVCKLHMDKPIKTFQGHTNEVNAIKWDPQGNLLASCSDDMTLKIWSMKQDTCVHDLQAHS KEIYTIKWSPTGPGTNNPNAALILASASFDSTVRLWDVERGQCIHTLTRHQEPVYSVAFS PDGKYLASGSFDKCVHIWNVQSGQLVHSYKGTGGIFEVCWNHRGDKVGASASDGSVFVLD LRKSNNDLASLFECPVCFDYALPPIMQCQSGHIVCSSCRPKLQLCPTCRGPLGNIRNLAM EKVASTVMFPCKYSSSGCTATLLHTEKTEHEDTCEFRPYCCPCPGASCKWQGSLEQVMPH LMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKIDGIQQFYA IVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHDGVQSAIMNSDCLVFDTNIAQLF ADNGNLGINVTISMCMAYQTFQQEYLQMPPITRAYTTACVLTTVAV--XIITPFQLYFNP DLIFKHFQLWRLITNFLFFGPIGFNFLFNMIFTYRYCRMLEEGSFRGRTADFFFMFLFGG LIMTVVVNLVFLGQAFTIMLVYIWSRRNPYVRMNFFGLLNFQAPYLPWVLLGFSLLLGNS VVVDLMGIAVGHIYYFLEDVFPEQQGGFKVLKTPSVLKWIFDSVPDDPNYNPLPPGGFAW GNGMEYLSDQGFRIDGRRPQELRKIECNMGVFTQADGSAYIEQGNTKVLAAVYGPHEVRG SRAKHDKALINCQFSMATFSTGERKRRPRGDRKSQEMTQHLKQTFEAAIMTHLYPRSQID IYVEVLQSDGGNYCACVNAATLAIIDAGIPMKDYVCACSSSFFNDTPIVDINYLEESSGP ELIVATLPKSDQMVFLEMNGRLHEDHLNKVMDTATKGCKDVYNILDRVVREMAGNYYFAI VGHNDNPVFEMEFIPPNKVNEPKRDDHRHLNQFIAHAALDLVDEQMWTTPNMYLKIVDKF NEWFVSAFVTAGRMRFIMLHDVKNEDGIKNFFQDMYETYIKFAMNPFYEPNSTIKSGAFE RKSQFYGRKYLTSQMRYAHTDVQIPDFSAYRRSSNNSSRKAFSYVMVAGGAVATTYAAKV TVVDLISTMSASADVLALAKIEIKLADIPEGKSATFKWRNKPLFVRHRTTEEIDKEGAVE VESLRDQEHDLDRVKKPEWLVLLGVCTHLGCVPIAGAGEYGGYYCPCHGSHYDASGRIRK GPAPLNLEVPTYEFVDE------MARQASRAGDPRKVSGELFTLTYGSLVAQLLKDYEND EDVSKQLEKMGYNIGVRLIEDFLARSAVGRCHDFRETADVISKVGFKMYLGITPAVTNWS PAGDEFSLLLENNPLTDFVELPEGHTTLSYSNILCGVLRGALEMVQMDVAVWFTQDHLKG DNITEIRLKFIKRLEDAVPAGEDENVKEFLAKAKEEFNKKWEEPSCNTASLDDFDRIKTL GTGSFGRVMLVQHKATKEYYAMKILDKQKVVKLKQVEHTLNEKRILQAISFPFLVKLEYS FKDNSNLYMVLEFVTGGEMFSHLRRIGRFSENQTRFYGSQIVLAFEYLHHLDLIYRDLKP ENILIDDTGYVKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVY EMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLKNLLQVDLTKRYGNLKNGVN DIKNHKWFATTDWIAIYQKKVEAPFIPKCKGPGDYSNFDDYEEEPLRISSTEKCAKEFAD FMLADTLLIVFISIVTALLGEGLTWLLVYRTDKYKKLKAEVEKQSKKLEKQKETAGESTE RSHKKKIERQEEKLKNNNRDLSLVKMKSMFAIGFAFTALLSMFNSIFDGRTVAKLPFVPF SLIQNLSHRNLIGEDYTDCSFIFVYILCTMSIRQNIQKMLGFAPSRAANKQGGGLFGTCT RYFDNWCEQEQVQFVENLLSRMCHYQHGQINSTLKPMLQRDFITALPAKGLDHVAETILS YLDAKSLCAAELVCKEWYRVISEGMLWKKLIERMTRTDPLWKGLAERRQWIQYLFKPKPG ESSKDNKFYRKLYPQIISDIERIENNWRTGRHTLQRIHCRSETSKGVYCLQYDDTKIVSG LRDNTIKIWDRQTLECVQVLTGHTGSVLCLQYDENIIISGSSDSTVRVWSVKTGEMLNTL IHHCEAVLHLRFSDGIMVTCSKDRSIAVWDMQSPTEINLRRVLVGHRAAVNVVDFDQKYI VSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACL RVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLAAALDPRAPAGTLCLRTLVEHSGRVF RLQFDEFQIVSSSHDDTILIWDFLNMAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNS TFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKS FENIRNWIRNIEEHASSDVEKMIL------------------------------------ ----------------------ADGESSADRNVEIWKIKKLIKSLEAARGNGTSMISLII PPKDQISRVAKMLADEFGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVIYCGT IVTDEGKEKKVNIDFEPFRPINTSLYLCDNKFHTEALTALLADDNKFGFIVMDGNGALFG TLSGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAEVAVQLFISNDRP NVAGLVLAGSADFKTELSQSDMFDPRLQAKIIKIVDVSYGGENGFNQAIELAAEALSNVK FIQEKKLIGRYFDEISQDTGKYCFGVDDTLRALEMGSVETLIVWENLDIMRYVLKNHQTD EERTLHLKPEQEKDKTYFTDKETGVELELVESMPLLEWFANNYKSFGATLEIITDKSQEG AQFVKGFGGIGGILRYQVDFQSLEAFDDLEDEYDLDDY---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------TIKGFEVVVEKEWLSFGHKFAQRIGHGEDKHSDADRSPVFLQFID CVWQMTKQFPNAFEFNENFLITILDHLYSCLFGTFLFNTDQQRVKEGVKTKTVSLWSYIN CQLEEFTNPLYQHVLFPVASMRRIELWTGYYLRWNPRMRPQEPIHIRNRELLVLKAQLQR RLEELQTE--------KPFIPHVPFDLIQCETMFPRVKPALEDKAFNDAILKRNADLTPS STEQASVLNLVTKIQGVMEGLVVAPNTFEAAQLEEVRQVGSHKKGTMMANHNVADLVVIL KTLPTVEAVQALGNKVVEEIN-TDPHEVLTMLTNDSGFEVSSAEATVKVLITTIPPNLKK LDPDLHLEGKVMQSHLAAIRHARWFEENAFHSSVKVLIRLLRDLKSRFAGLDPLTPWMLD LLAHYSIMNNPNRQPLPISTAFRRALQLLATGFFVPGSAGITDPCEQGNVRVHTSMTLEQ QDQVCYTAQTLVRVLSHGGYKQILGLEGNASIATEMSVWEGVVVTPSDKAYEKPEK---- ------------------------------------------------------------ ------------------------------------------------------------ -------RRAAIAQALSGEVNVVPPSRLMALLGQALKWQQHQGLLPPGTTIDVFRGKAAV KEQEDEKYPTQLSKTIKFGQKSHIECAKFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLK YQAQDNYMMMDDAVLCMGFSRDSEMLATGGQDGKIKVWKILTGQCLRRFEHAHSKGVTCV NFAKDNSQLL-------------------------------------------------- ---------------------GSDITVHSIHLLPRNVEQFVVCNRSNTVVIMNMQGQIVR SFSSGKREGGDFVCATVSPRGEWIYCVGEDMVLYCFSSSTGKLERTLTVHEKDVIGLAHH PHQNMVATYSEDGLLKLWKPMAQAAQKSTSLATFATPRLQTFWRYARVELVPPAEMPAVQ TGFSNLISAKKGAWTKVTVKEATLVTIEVLCWFFIGECIGKRAIVGYPVPGGTHY---SI PKFYFRLPSEDEFLLQKLREESRAVFLQRRSRELLDNDELQGLWYLLDKYHTPPLVGEEQ MINYEDFLKVGTEAGQKCKPFFTATVFAKLLQQDPYGRISIMQFFNYVMRKVWLHQTRIG LSLYDVAGQGFLKESDLENYILELIPTLPQLDGLEKSFYSFYVCTAVRKFFFFLDPLRTG KVRIQDILACSFLDDLLELRDEDLSKDMQESNWFSAPSALRVYGQYLNLDKDHNGMLSKQ ELARYGTGTLTEVFLDRVFQECLTYEGEMDYKTYLDFVLALENRKEPQALQYLFRLLDVQ AKGYLNVFDLNYFFRAIQEQMRMHGQEPVSFQDVKDEIFDMVRPADPYKLTLQDLINSGQ GDTVISILIDLNGFWTYENRE-EIVRGQVFEVGPRYSNLAYIGEGAYGMVVSSYDNVTKQ RVAIKKISPFEHQTYCQRTLREIKILTRFRHENIIDIRDIIRAKTIDEMRDVYIVQCLME TDMYKLLKTQKLSNDHVCYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFG LARVADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDVWSVGCIL----------- ------------------------------------------------------------ ------------------------------------------------------------ -----ALTPPKTTPEWVKFCKQLFGGFSLLLWIGAILCFVAYSIQASTYEDAPGDNLYLA IVLMFVVIATGCFSYYQEAKSSNIMESFKKMVPQFAIVKRNCEKLNVHAEELVVGDIIEV KFGDRVPADIRVISAHGFKVDNSSLTGESEPCSRTADFTNENPLETRNLAFFSTNAVEGT CVGIVVATGDHTVMGRIANLASGLEMGETPIAREIAHFIHLITGVAVFLGISFFIIAFIL GYNWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTI CSDKTGTLTQNRMTVAHMWFDNRIVEADTSEDQSNATYNRESPTWMALARIAMLCNRAEF KVGQENVPVLKRECNGDASESALLKCVELSIGKVTDFRKANRKVCEIPFNSTNKYQVSVH QNDDRYQVVMKGAPERILDRCSSILINNEEKALNDEWREAFNTAYMELGGLGERVLGFCD YYLPTEDYPKDYPFDADEENFPLSGLRFVGLMAMIDPPRAAVPDAVGKCRSAGIKVIMVT GDHPITAKAIAKGVGIISEGNETVEDIAARKGIPVSEVNPREAKACVVHGSDLRDMTPAQ IDDILLNHSEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIA GSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLLFILAD VPLPLGTITILCIDLGTDLIPAISLAYEQAESDIMKRQPRDPLHDKLVNHRLIGMAYGQI GMIQASAGFFVYFVILAENGFWPSRLLGIRKAWDSKGVNDLEDSYGQEWTYAQRKVLEYT CHTAFFVSIVIVQWADLCICKTRRNSIIHQGMMNKHLTFGLFFETGLAAFLCYCPGLDKG LRMYPLKFSWWIPAMPFSIIIFIYDETRKYFLRRYPGGWLELETYYTFKNLSKSKQIAAG LTAGGIGLGVALNDLVLHPPQFPWSHKGIFQAVDHASVRRGYQVYKEVCAACHSMNYMYY RNLVGVCYTEDEAKAEAEAINVPDGPNDEGNMFERPGKLSDGFPKPYANDEAAKAANNGA LPPDLSFIVNARHGEEDYIFSLLTGYCDPPEGITLGEGQAYNPYFPGGAIGMAQQLYNES VEYEDGTPATVSQMSKDICTFLRIAAEPEHDQRKRMGLKCMIVMILAASYYVKRHKWSVL KSRKLA----------------------------------------DTPLVKLNSVPKAA GLECDVLAKCEFFNAGGSVKDRIGLRMVEDAERDGTLKKGDVLIEPTSGNTGIGLALAAA VKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTSASFDSPESHIGVANRLLQEIPNSHI LDQYRNPSNPLAHYDGTAEE---------------------------------------- ------------------------------------------------------------ ------------------------------------------------------MSDLGS EEEQGPYLGEYEGERNDREERHGYGKATLPNGDTYEGVYENGKRHGQGVYRFKNGARYIG EWLKNKKHGQGTFIYPDGSKYEGSWVEDQRCGFGKYSYINADTYEGEWQNHVRHGQGAYT YAETGTKYQGMWKEGKRDGHGELIHANHKYVGPFRDDKPEGKGKYVFDIGCQQHGDYVMP DIMRLITKDLSEPYSIYTYRYFIHNWPKLCFLAMDGTKCVGAIVCKLDVHKKLVRRGYIA MLAIDQEYRRRGIGSHLVMKAIRAMVSDDCDEVVLETEITNRAALRLYENLGFVRDKRLF RYYLNGVDALRLKLWLRSIDALRFQLPPNLRKCLREEIHKDVLVTGEYELTDSPGQKTAL LVTDSKGHVLYNKEDATKGKFAFTTEEYDMFEVCLESKMVMGGHGGEKEVFLDMKHGVEA KNYADIAKAEKLKPLEVELKKLEDLSESIVNDFAYMRAREEEMRDTNESTHSRVLYFSIF SMACLLGLATWQVLYLRRFFKAKKLIEEMESGRTSSVGNDILGFKGSVVNHPDHGNLDWT KICEESAKVITFIDLAGHERYLKTTVFGMTGHAPDFTMLMIGANAGVVGMTKEHLGLALA LNVPVFVVVTKIDMSPPNVLQDTLKMLQKILKSPGCRKIPVLVQSMDDVVVSATNFTSER MCPIFQVSNVTGENLDLLKMFLNLLSPRIQNEPAEFQIDDTFSVPGVGTVVSGTTLKGVI KINDVLLLGPDPLGNFMPIAVKSIHRKRMPVKEVHGGQTASFSLKKSAIRKGMVMVAPRL EPKACWEFEGEILVLHHPTTISPKYQAMVHVGSVRQTASILSMSAEHMRTGDKAVVRFRY IKNPEYLRTGMRMVFREGRTKAVGNITKLFPHVSANTRQQRMAKKTADQEKISRVDDHHF YLFKVLRAHILPLTNVSFNKSGSSFITGSYDRTCKVWDTASGEELHTLEGHRNVVYAIAF NNPYGDKIATGSFDKTCKLWSSETGKCYHTFRGHTAEIVCVAFNPQSIVATGSMDTTAKL WDVISTLNGHSAEIISLAFNTLGSMLITGSFDHTVSVWERRMHTLIGHKAEISSAQFNWD CSLIATGSMDKTCKIWDTQTGQCIGTLRGHDDEVLDVAFDFTGQYLLTASADRCFNAVTH SKLEGHEGEISKITFNPQGNRILTASSDKTARLWDPETGECKQILEGHTDEIFSCAFNYE GNTIIT------------------------------------------------------ ----------------MTEVPPLFVIEFLHRVMDIFEDYFTECTESAIKDNYVVVYELLD EMLDNGFPLATESNILKELIKPPNLLRTITDTVTGKSSTVSSTLPTGQLSNVPWRRTGVK YTNNEAYFDVIEEIDAIIDRSGSTVFAEIQGYIDCLIKLSGMPDLTLSFVNPRLLDDVSF HPCVRFKRWESERILSFV------------------------------------------ ----------------------SVLNMTLTPSQGKYSFDPVTKVMSWDIGKIDPQKLPNI RGSINLQTGAPPPDSNPNIQVHFTINQMAVSGIKVNRLDMYGEKYKPFKGVKYVTKAGKF QVRTMATAVKPAPRHATSDWFASNHAISTNAERQRTASHDTRQEGRFLRNETDNKTKWDQ LDNNTRLDDRITNIRKWKDILEKTLADIDQEIKDLSDAKEETEKSLEAKNLPTEVNIENL VTREGRQDIDVVEDEVEDQLHKEQGVIEGIKRQLQQKVDESFEHLCILQEARQQILADLQ DKNVALGIDVDQYNLTEESGGISFKPDSLRVPKGSTSPQSWEDFSRYNKDRAEAEMGASK RLREAIHHTLQQTDNDLEAQHTATDYAFRKRMHETKRAIDELKWQKAQTEEEIGEQEEEI RRLQDAIRAKINPLKLAQTRLENRTYRPNVELSRDNVQYGLVDEVKQLEASKKALEEKLK QAQHALDGLEQNLHRINQDLQCKTNSLKLEEQCMESRQKLERNMLLTGITNLKDVMADLV PKHQATVKEFRAKAGSKVVGEVTVDMMYGGMRGIKGLVTETSVLDAEEGIRFRGHSIPEC QKVLPRAPGGEEPLPEGLFWLLCTGDLPTEEQVKAVSKEWANRADLPAHVVTMLNNFPSK LHPMAQFSAAITACNSESKYAQAYADGVNKASYWEYIYEDSMDLIAKLPTIASIIYRNLY RDGTSITAIDPEKDWSANFVSMLGYEDKYFTDLMRLYLTIHSDHEGGNVSAHTTHLIGSA LSDPYLSFAGGMNGLAGPLHGLANQEVLVWLTKLKYTQEDLKDYIWTTLKAGQVVPGYGH AVLRKTDPRYTCQREFALKHLPNDPMFKLVSDVYQVAPGILTEQGKTKNPWPNVDAHSGV LLQYYGMTEMNYYTVLFGVSRALGCLSSLMWDRALGLPIERPKSMSTEGLIKFVKMPFVP PKQEKCERCTKSVYAAERMEAGGRIWHKFCFKCSECNQQLNLNNYGQNDGILYCKKHF-- ---------DKLFVHRDSTENNPDVPFEFTPENIKRADALIKNYPVGHERAAVMPLLDVA QRQLGWLPISAMNYVADYLKMPRMRVYEVATFYTMYKREPVGKYHLQICTTTPCMLGGIG SEPILNCIKEKLGIQVGQTTPDKLFTLEEVECLGACVNAPMIQINDTYYEDLTVEDMSSI LDDLKAGKVPTPGPRSGQNGRFTSEPKGGLTSLTEPPTGPGFGLIAEL------------ -------------------------------------------KELKHKNIVRLHDVLHS DKKLTLVFEYCDQDLKKYFDSCNGEIDPDIVKSFMYQLLRGLAFCHSHNVLHRDLKPQNL LINKNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIF AELANAGRPLFPGNDVDDQLKRIFKLLGTPTEDSWPGMTQLPEYKPYAMYHPNSQVVSKL NSKGRDLLLNLLVCNPTKRMSAEDGMQHLYFADLNPAIK-DPKFFQYSGPIPRVNYPLQD ECDDWPLEYCEYHPNYEKAKIWMAKNLTDDMKKLYLKRQKRGGKGMIKTKKKAEPQGVCL SRASRGKKKFVTVVTGLATYDIDLKVASKFFGSRFACGSSVTGEDEIVIQGDVKDDLYDV IPEKWRQIDEDSIDDLGDQKRWFCVDRSAAWQQMKDQMCGTLVARNSLMCGTPELYRKWW FFPSPPGGLIAVQPHGFTGIDVPDKEILVTDAGKLYVLDTLLARLKSDGHRVLIYSQMTR MIDILEEYMWHRKHTYMRLDGSSKISDRRDMVADFQTRSDIFVFLLSTRAGGLGINLTAA DTVIFYDSDWNPTVDQQAMD---------------------------------------- -------------------------------FDVVPKDIRNLRACLLCSLVKTFEQFEYH GCENCEEYLHMKNQRDAVYDCTSSSFDGLVAMMAPEDSWVAKWQRITRFTKGCYAVSVTG RLPPGIVRELKSKGINYRPRDVS------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------QQNGLVPIVEPEVLCDGDHDLPTAQRVTEQVLAFVYKALNDH HVYLEGTLLKPNMVTAGQSCATKYSPADVAAATVLTLQRTVPAAVPGITFLSGGQSEEDA SVHLDAMNKKPWGLTFSYGRALQASVLAAWQGKAENIKAAQDTLMLRATANGKAALGQYE GGISGAAGQSLFVANHAY------------------------------------------ ------------------------------------------EENPSGVPQFWLTTFKNV DMLSEMIQDHDEPILKHLQEVKVKFSMGFTVEFFFEANDFFTNNLLTKEYVMRSEPDPAE PFGFEGPEIIKCKGCTIDWKKGKNVTVKVIKKVQKHKGRGTKRTVTKTVQNDSFFNFFSP PEVAEGEPDEDTEAILAADFEIGHFIRERIVPRAVLYFTGEALEEEEEGDEDEGEIILLK EGTDSSQGKPQLISNINACNAIVDAVRTTLGPRGMDKLVVDNNGKATISNDGATIMKLLD IVHPAAKTLVDIAKSQDAEVGDGTTSVVLLAGEFLKQCKPFVEEGVHPQVIVRAFRKATY LAVKKIQDIAVQIKKNPSEQKALLLKCAATALSSKLVARQKEFFAEMVVDAVMHLDELLP LNMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYSNPKIALLNIELELKSERD NAEIRVNSVEEYQSIVDAEWKILYDKLEKIHASGAKVVLSKLPIGDIATQYFADRDLFCA GRVPDEDLKRTMKACGGSIQTSAGSLTLGRCGQFEESQIGGERFNKFTECVNARTCTLII RGGAEQFMEETERSLHDAIMIVRRAVKNDSVVAGGGAIEMELSKYLRDFSRTIPGKEQLL IGAMAKAFEIIPRQLCDNAGFDATNILNKLRQKHAGTWFGVDIVNEDIADNYNACVWEPS IVKINALTAASEAACLILSVDETIKNPKAGGEGMGRGRGRGRPMKRNNMIPNGHFHKDWQ RWVRTWFNQPARKIRRRQNRIKKARAIAPKPVGGALRPIVRCPTFKYNTRVRSGRGFTLE ELKAAGIGKREARTVGIAVDFRRRNKSVESLQQNVQRLKEYRSKLILFPKKLTKPKKGDA TAEELKMATQLSGPVMPITQVVKKEKAR-------------------------------- ---MPNIKVFSGTSHQDLAQKICDRLGIELGKVVTKKFSNQETSVEIGESVRGEDVYIVQ SGCGEVNDHLMELLIMINACKIASACRVTAVIPCFPYARQDKKDKSPISAKLVANMLSVA GADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENIAEWRNSIIVSPDAGGAKRVT SIADKLNVDFALIHKERKKANEVASMVLVGDTTGKVAILVDDMADTFGTMVHAAEKLLDA GALKVYAICTHGILSGPAVSRINNSAFETVVVTNTIPQDEKMKNTAKLECIDISMMLSEA IRRTHNGESVSYLFSHVPLLTCRFYEHRFPEVEDVVMVNVRSIAEMGAYVHLLEYNNIEG MILLSELSRRRIRSINKLIRVGRNECVVVIRVDKDKGYIDLSKRRVSQEEIVKCEEKFAK AKCVNSILRHVAELLNYERDDQLEELYMQTAWYFDRKYKSPGAAYDVFKHAVANPEVLDE CNLEPETNNVLLSNIKRRLTPQAVKIRADLEVACYNYEGVDAVKNSLRAGLSLSTEDMPI KIKLIAPPVYVMTTQTLERQEGMARGQQKIQSQQKNAEKLAKIKHNQKASAQAALTFVCS VCKSQMPDPKTYKQHFENKHPKAALPVELKDI---------------------------- ------------------------------------------------------------ ------------------------PFGEDGFHEKDGKAFCRDDYFELFAPKCGGCGRPIM DNYISALNRQWHPECFVCMECRFPFGGGSFFDHEGMPYCETHYHARRGSLCAACQKPITG RCITAMYKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCHPCFIK--MRPLTEEETKTFFE KLSKYIGENIKLLIDRPDGLYCFRLHKDRVYYVSEELLKKAGHIARENLISFGTCFGKFT KSGKFRLHITALDYLAPYAKFKVWVKPSAE------------------------------ ------------------------------------------------RKFFVGGNWKMN GNKASIDGIIQFLNEKNPNTEVVVSPSPCYLEYVRGKLIGVAAQNCYKCEKGAFTGDISP AMIKDCGCEWVILGHSERRHVFGESDQLIGEKVAHALASGMKLIPCIGEKIEEREAGKTE EVCFRQMKASDWGRVVIAYEPVWAIGTGKTASPDQAQEVHLALRKWLSDNVSADVAKSCR ILYGGSVSAGNCKELGGKPDIDGFLVGGASLKPDFIEIINAR------------------ ------------------------------------------------------------ ----------------------------------VQNFHMSWKDGLAFCALIHRHRPELI DYHKLSKDNPIENLNTAFDIAEKYLDIPRMLDAEDMVNSVKPDERSVMAYVSSYYHAFSG AQQAETAANRICKVLKVNQENERLMEEYERMASDLLEWIRRTTPWLENRTTDNTLPGTSR KLEEFRDYRRKHKPPKLEEKAKLETTFNTLQTRLRLSNRPAYLPTEGKMVSDIANAWKGL ERAEKGFEEWLLSELQRLERLDHLAKKFKHKCDIHEGWAFGKEDMLQAQDFKKCRLNELK ALKKKHEAFESDLAAHQDRVEQIAAIAQELNALDYHDCPNVNARCQRICDHWDLLGTLTQ QRRTALEEAERILERIDQLHLEFAKRAAPFNNWMDGAKEDLVDMFIVHTCEEIQGLIDAH EQFKQTLGEADKEFNAVMALQQEVNRIAQQYGITGGGENPYTTLSAQDIAVKWTEVKQLV PKRDSVLQQEMIRQQNNERLRRQFAQKANVVGQWVERHLDAASAVGLQKGSLEDHLNKLR GVEKEVMAFKPNIDELERYNQEVQEAMIFENRHTPYTMETLRVGWEQLLTSVARNINEVE NQILTRDSKGISNEQMDEFRKSFFHFDKKRNRRLEPKEFKACLVSLGYNIRDDRQGEADF QRIMSIVDPNHSGFVTFDSFLDFMTRETTDTDTAEQVMQSFRILAGDKAYITADILRREL PPDQAEYCIQRMAPYTGRDAIPGALDYTSFSTALYGESDL-KLGIDEVDLKDKRVLIRVD FNVPLKGSEITNTQRIDAAVPTIHHALNNGAKSVVLMSHLGRPNGLKNDKFTLKPVADAL KKILNKDIQFLDDCVGPSVEAACADPATGSVILLENLRFHVEEEGKGVDADGQKVKADAG KVEEFRASLSKLGDVYVNDAFGTAHRAHSSMVGCALPQKACGFLMKKELTYFSKALENPE RPFLAILGGAKVKDKIQLIENMLDRVNEMIIGGGMAYTFLKVIHGMKIGNSLYDEDGSKI VKSLMEKAEQKGVKVHLPVDFVTADNFAENPNMGKATVESGIPEGWMGLDCGPESSAKFA EVAGRCKTIVWNGPLGVFEFPNFANGTKNMMDVVVHATTKGATTIIGGGDTATCAAQWKT EDKVSHVSTGGGASLELLEGKMLPGVTALSD-MSGIPPKSWQPPTVTLETTMGNIGIELY WKHAPNTCRNFAELTRRGYYNGIKFHRIIKDFMIQGGDPTGTGRGGASIYGPQFDDEIHP ELKHTGAGILSMANSGPDTNGSQFFITLAPTQWLDSKHAIFGRVATGMLVVNRIGMVEVD NNDR-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------VKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDQACAGLNGMQLG DKKLIVQRASVGAKNAQQAPVQLQVPGLNISSIPTEVLCLMNMVSPDELEDEEEYEEILD DVKEECGKYGQVKSLEIPRPIKGVEVPGCGKIFVEFSSLIDCQKAQQALTGRKFSNRVVV TSYFDPDRYHRREFFLPLFDRVLVQRAVAETKTKGGIMLPEKAQGKVLEATVIACGPGAK TESGNVIPNSASVGDKVLLPEYGGTKVILEEQEYFLFRDSDILGK--RLKTQIPDIRTSL DIVKHMEEKKDAMQTHFQLADQLYAKAKVPPTENVCLWLGANVMLEYNLPEAHQLLEKNA AKKSLEQVEEDLGFLRDQTTTIEVNMARVYNWDVKRRQ----MADDALAKAGLHFDELNK IRVLEPEVSQQTNELKEECKEFLDKMTEFQKIVGSFIQLVNTASQEVEKEKMKAIGSRNL LKSVSKQREAQQQQLHALITEKKMQLERLRIQHESLLKEEQEQNEFIEQFIMQKRSRSKD RDRKDRRRSRSRSRDRRDLSPEERDARTVFCMQLSARIRPRDLEEFFSSIGKVKDVRIIT DNKTRRSKGIAYVEFQELESVPLAIGLSGERLLGVPIIVQASQAEKNRLAGLSGPMRLYV GSLHFNITEDMLRGIFEPFGKIDEVKLISNHDSGRSQGYGFVTFHNSEDAKKALEQLNGF ELAGRPMKVGHVTERTADTSILDSDEMDRAGIDLGATGRLQLMAKLAEGTGFQIPDAAAN ALNTPTAAATPPIATQCFMLSNMFDPHTTQMSWEQEIRDDVIEECNKHGGVLHIYVDKAS PQGNVYVKCPSISAAVASVQALHGRWFAGKVITAAYVPLPNYHALFPDAVRATALLMPS- -QREDEISPIPPQTRKRMPRRGAVSAEVYTEEDAASYVKKVVPKDYKTMAALSKAAAKNV LFSHLDDNERSDIFDAMFPVHRHAGEIIIQQGDEGDNFYVIDQGEVDIYVNNEYISVIGE GGSFGELALIYGTPRAATVKAKTDVKLWGIDRDSYRRILM-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------------WI ETQAKKAALKLEKLDSDLKNYKSNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDY CTSAKHVVNMCLNVIKVSVYLQNWSHVLSYVNKAEATPQVTEQKDGSQAVITKLKCAAGL AELATKKYKSAAKNFLQSNFDHSDFPELLSPNDIARYGALCALASFDRLELQKNVMSSSS FKLFLELEPQLRDIIHKFHESKYASCLKLLDDLKDSLLLDMYLAPHVNTLYTQIRNRALC QYFSPYLSADMNKMASAFNTTVGALEDELMQLILDGLINARIDSHNKILYAKDIDQRSTT FDKSLSMGKEYQRRTKALILRSAMLRNQIHVKSPPREGGQGGEMAIAPGTA--MPQKNEM MDKAEDVADQVLRHGKHILPHVARLCLISTFLEDGIRMWFQWNEQRDYINATWGCGYILA TLFVVINLVGQLGGCMMVLSQKKVSIACGILFFIIGLQTLAYSILWDLKFLMRNLALAGG IILLLAESKGEGRSIFPGLPSLGENNPKTYMQLSGRILLVLMFLTLLRFEFSFLHILQNL IGTALIVLIAVGYKTKLASLILVGWLTVLNFYFNAWWNIPDYKPMRDFLKYDFFQTLSVI GGLLLVVTLGPGGYSMDEHKKKWQQKVTLIPGDGVGPELCHTVKEVFKAAGVPVDFEELF VSANRVCLKGIISTPLETLNMRIRRELDLFANVVKVESLPGYSTRHNNLDIVVIRESKEG EYSSLEHESVPGVVESLKIITRENSIRIAKFAFDYATKHGRKKVTAVHKANIMKLGDGLF LESCREVSELYPKIKFENMIVDNTCMQLVSNPYQFDVMVTPNLYGNIIDNLAAGLVGGAG LVPGESYSPQVAVFEPGARHSFARSAGRDEANPIAFLFCAANMLNHLHLEFYGTLIRDSV LKVVKAGKVRTPDMGGYNTHSDVTQAVIRNVSDEFERFMDRAARVIERAIYEDVDLLTDY SGIEGEDGGNEGERVKLNRQFFDERWSKHRTITCMDWSVQHPELIVASYNNNEESPNEPD GVALIWNIKYKKNTPEYVFHCQSAVMSTCFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPV QRTPLSSAAHTHPVYCVNVVGTQNAHNLISVSTDGKMCSWSLDMLSQPQESLELQYKQSK IAVTSFSFPAGDVNKFVVGSEEGAVYSACRHGQKAGINDVFEGHQGPVTGIDCHTVPGAI DFSPYFITSSFDWTVKLWNIKENRPLHSFEDNSDYIYDARWSPIHPALFATVDGMGRLDL WNLNNDTEVPTTSVINVALNRCRWHQSGHNIAVGDDMGKLHIYDVGESLAVPRTDEWNRF VHTLADLKTQQDEADEDNLEQQMMQVATAMEQQVDAEINKLENMGEDDFEALRRQRLAGL KKAQDQKREWMTLGHGKYEEIPEEKEFFDVCKKSKNVVCHFYRDSAFRCKIVDKHMALLA PKHMECKFVKINAEKCPFLTQRLKIKVIPTILISRDSKTVDFIVGFDDLGGHDEFTTEVL EWRIARADVIHYSGDLLEPPTSGKSKKTIRGRDDDSKSIVLVGTGGYDKLKVQQKPKPGE GEVLVQVKAAGLNFAELLMRMGLYPGSIKLPGVLGFEGAGVVTAVGEGVNEFEVGARVIC SKGMWSEYVTQCFAMPEEMSFEEGAALPVTYITAYFLLFEFGNLRPGKSVLCHMAAGGVG TAVAQLCKSVENVTVFGTASAKHEMIKENGITHPIDYRTQDYVQEVKKISPQGVDIVLDP LSGEDSVKGFQLLKPFGKIVHYGVANAASGTSKSLLSTVKMWWNTKSISPLNIIGMNKAI CGFHLGGLVAMHKILDLYRDGKIKPIIDSTWAYEDVGRAMAKMHERKNIGKIILSVDKMS RK-TPSDFLKQIIGRPVVVKLNSGVDYRGVLACLDGYMNIALEQTEEYVNGQLKNKYGDA FIRGNNVLYISTQKRRI----QSALLLQRQLAELSKHPVEGFSAGLIDDNDIYRWEVLII GPPDTIFEGGFFKCHLTFPREYPLKPPKMKFITDIWHPNIDKSGDVCISILHDPGEDKYG YERPEERWLPVHTVETILVSVISMLADPNDESPANLDAAKEWRECREEFKKKVARCVRKS QENTIRPENPVVKQTLIDFGKYVGECMPKYVQKVEVSHGNELDIMIHPDGVIPVLTFLKD HTNAQFTNISDIAGVDVPTRQQRFEVVYILMSVRFNARIKVKTYTDELTPLQSACSIFAG ADWYEREIWDMYGVFFANHPDLRRILTDYGFEGHPFRKDFPLQGYVELRYDDEVKRVVAE PIEMAQEFRKFEYSTPWEAFPNYRDSLNPYCQVDYRAKIWSCNFCFQRNPFPPQYAAISE QHQPAELIPQFSTIEYTLTRATCHPPVYLIVLDTCMDEEDLQAVKESLQMSLSLLPPNAL IGLITFGKMVQVHELGCEGCSKSYVFRGTKDLTAKQIQEMLGIGRAAAALPANRFLQPVH KCDMALTDLLSELQRDPWPVSQGKRPLRSTGVALSIAVGLLECTYPNTGARVMMFVGGPC TQGPGMVVDDELKHPIRSHHDIEKDNCKFMKKAIKHYEGLAGRASANGHVIDIYACALDQ TGLLEMKSPPNLTGGHMVMGDSFNTSLFKQTFQRVFSKDVKNEFRMAFGANVEIKTSREL KVQGCIGSCASLNMGGSVSDTEIGLGGTTQWRMCGLYPNTTYAFYFEVVNQHNAPIPQGG RGYIQFITQYQHSSGQKRVRVTTVARNWVDASINVHHIAAGFDQEASAVLMSRIATHRAE TDDGPDVLRWLDRMLIRLCQKFGEYNKEDPNSFRFAEQFTLYPQFMFHLRRSQFLQVFNN SPDETTYYRHMLTKEDLTQSLIMIQPILYSYSFNGPPEPVLLDTSSIQPDRILLMDTFFH LLIYHGETVSQWYSSGYHDLPEYENFKQLLQAPIDDAQEILQTRFPMPRYIQTESGSSQA RFLLSKVNPSQTHNNMYADGGGHVLTDDVSLQVFMEHLKKLAVSS--MAALSPDDQMKLI QDLEIEMMADMYNRMTSACQKKCVPPKYKENELSKGEAVCLDRCVAKYIDIHDRIGKKLT AMSMQDEETMKKIQTPQPPAVIHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYR KKVVLDGEEVQIDILDDYAAIRDNYFRSGEGFLCVFSITEQESFQATAEFREQILRVKSD ECIPFLLVGNKADLEEKRNVLVEEAQSRAQQWNVPYVETSAKTRANVDKVFFDLMREIRS RKMDDKSHKRKCCILKLYTGLRQVVTDHLVVKVRQDVLDSLNNNFLQTLNNAWNDHQTSM VMIRDILMYMDRVYVQQNNVDNVYNLGLMIFRDQVVRNPIIRDHLRQTLLDMVAKERRGE VVDRGAVKNACQMLMILGIDSRAVYEEDFEKPFLDRSAEFYRLESQKFLAENSASVYIKK VEARINEEAERAAHYLDKSTEEPIVKVLEDELISKHMKTIVEMENSGVVHMLKNNKTEDL GCMYKLFIRVPSGLKTMCDCISTYLREQGKALVEE-EAGKNAIAFVQSLLDLKDRFDHFL HESFNDDKQFKQMISSDFEYFINLNTKSPEYLSLFIDDKLKKGVKGMSEQEIENVLDKSM VLFRFLQEKDVFERYYKQHLAKRLLLNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFKD MTVSNSTMDEFKTHTHQLTNMYGVDLFVRVLTTGFWPTQSATPKCNIPYAPRMAFEAFRR FYLGKHSGRQLTLQPQLGSADLNATFYGLKKDDASSSKGPRRHIISVSTYQMVILMLFNN RDRLTYEEVKNETDIPEKDLMRAVQSLALGKITQRILVKEPKTKEIESDHTFSVNDQFTS KLYRVKIQTVAAKGESEPERKETRSKVDEDRKHEIEAAIVRIMKARKEMQHNVLVAEVTE QLKARFLPSPVIIKKRIEGLIEREYLARKADDRKIYTYVADRIPIFPSRMNLTIMKLRLK GAQKGHSLLKKKADALTLRFRSILKKIIETKVLMGEVMKEASFSLAEAKFTMGDFNHLVL QNVNKAQVKVRTKTDNVAGVLLPVFENYNDGSDSYELTGLSRGGQQVDKLKKNYAKAVEL LVQLASLQTSFITLDEVIKITNRRVNAIEHVIIPRIERTLQYITTELDENEREEFFRLKK VQNKKAKMRPANLLDDRDEDLLFPLRVLITGAAGQIAYSLLYSVAKGDVFGKEQPIILHL LDIDAMMEVLKGVVMELDDCALPLLKEVIPTSDVTTAFKEIDVALLVGAMPRREGMERKD LLKANVKIFKQQGQALDQNAKKTVKVLVVGNPANTNCFICKKYAPSVPAANFSCLTRLDQ NRAQSQIANRQDVYNVTIWGNHSSTQFPDVAHAKVAMDAVKDDSWLKNEFVKTVQTRGAA VIAARKLSSAMSAAKAICDHMRDWWHGTPSDRWVSMGVVSDGYGIEKDLVYSFPVTIDRN WTVVQGLQCDDFAREKMESTMKELVEERDAALETC------------------------- ------------------------------------------GVPQVYYFGPCGKYNALV LELLGPSLEDLFDLCDRKFSLKTVLMIAVQLITRMEYVHSKHLIYRDVKPENFLIGRQSN KKQHIIHIIDFGLAKEYIDPETHKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEAL GHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENYPEELATYLRYVRRLD FFETPDYDYLRKLFLDLMAKKGWEADWEFDWTGRQL------------------------ ------------------MTTLRSFTCDDMFRFNNVNLDPLTETYGLPFYMQYLAHWPEY FKVAESPSGEIMGYIMGKAEGHGENWHGHVTAVTVAPEYRRLGLAGKLMGILEEISEKKR CYFVDLFVRVSNKVAVDMYHRLGYFVYRTVLEYYSGDVDEDAYDMRKALSRD-------- ----------EQQLDCALDLMRRLPPQQIEKNLTDLIDLVPGLCEDLLSSVDQPLKIARD KAVGKDYLLCDYNRDGDSYRSPWSNSYDPPLEDGAMPSDRLRRLEIDANSAFDQYRELYF EGGVSSVYLWDLEHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRNAHYKLTST AMLWLQTNKSGSGTMNLGGSLTRQVEQDAAVSEANPHIVNIGKMVEDMENKIRNTLNQIY FGKTKDIVNGLRSTVPLQRENLKNDLAQALRTRSA-DDDLDEVPDQLEEGDHNGNVEILA AGERVPPEKRNTTTYMTKYERARVLGTRALQIAMCAPVMVELEGETDPLIIATKELKARK IPIIIRRYLPDGSYEDWGIDELIIND---------------------------------- ---------------------------------------------ITRSPAMMNIVMKNS WMSIIGTMVAMVGSGMVARSIPYKEGAKQLAWAVHAGIVGAVIAPLTFLGGPLLVRAACY TGGIVGGLSTLAMCAPSEKFLNMGGPLAMGLGVVFMSSLGSMFLPPTTALGAGLYSISLY GGLVLFSAFLLYDTQKIMKKAETHPVYAVQPYDPVNASISIYLDTINIFIRMAMILAGGG NRRRMEIVYVYTKKRQEFGRQCNFSDRPAELHVDIVPDPSLTENFIERNPVDTGTQNVQE MSEHEINTERFETDTRGVNHTEGGWPKDVNPQEIEQVMRYRKKVEKDENYVYTMLQLAGV MEHCIRQNNALDIYEEYFEDIAIDEGDEPPSAKTINVFRDPSDPKRTSTHISWFPDGARK LAIAYCNLEFQGSSPDTMNSYIWDIENPNKPEMTLKPVSPLVVLEYNPKDPHILIGGQYN GQLAYWDTRKGSQPVEMTPIEHSHREPAYKVIWLQSKTGTECFSASTDGQVLWWDTRKLG EPTEKLYLDPTKKQDFSKSLGAMSLEYEATIPTKFMVGTEQGSIMSCNRKGKTAADKITA IYPGHHGPVYSLQRNPFFPKNFLSVGDWTARIWSEDIRESSIMWTKYHMAYLTDGCWSPI RPSVFFTTKMDGTLDIWDLIFKQNDPTLSLQVCDEPLHSIRVQEHGRLVACGSRGGTTTL LELSDGLCTLARNEKALVTAMFERETRREKILESRHREMKLKERNKSSWEELVSRVGPIA SPLAPRKLTKKLYKIIKKAIRKGVKEVQKFIRKGEKGIVIFAGDTSPIEVICHMPVVCEE ANLPYCYTPSKEDLGAACGSKRPTCMVLVKTNTDYEDLFDELSSDVKDLPQPLMPVENLE DQGLPKNPNFDFAQWRFMMSTDRYRNDQVLRNKLMGAIEKDDMAPFYEETCTELGWPVDQ DLLQKMKAANDVEIKKMEDAVEDAEKNLGETEVRDAMLAKAEYLCRIGDKDGSVSQFRKT YEKTVALGYRLDMVFHQIRMGLFYMDHDLIKRNLEKAQSLIDEGGDWDRRNRLKVYKGTY SMAIRDFKTAANLFLDTVATFTSYELMDYPEFVTYTVYCSMIALDRPDLRKKVTRGSEIL EVLHGLPEVKQYLFSLYNCQYGDFFQCLATVEQQMKFDRLLAPHFRFYIREMRIHVYSQL LESYRSLTLDYMANAFGVTQDFIDQELSRFIAAGRLHCKIDKVGGIVETNRPDSKNWQYQ ATIKQGDLLLNRIQKLSRVINIKRGLKTTTKPIAGIPYKEIKVGVPKEIFLNERRVAIVP ATVATLKKGFLVNVEENAGVEAKFTNDDYAAAGANISRNAAFESDMVVKVRAPTVDEVKL LREQNTLYSLLYPAENKELLDLLAERKATVFAMDCVPRISRAQAFDVRSSMDNISGYKAV VEAANHFGRFFTGQITAAGKVPPAKVLVIGGGVAGLASMGTAKNMGAIVRGFDVRAAVKE QVHSMGAEFLEVPIKESGEGTGGYAKEMSKEFIEAEMALFARQAKEVDIIISTALIPGRK APILITKQMVDSMKPGSVVVDLAAEAGGNIETTRPGEVHKYNEVTHIGYTDLPSRLPTQA STLWSNNVSKLILSFSYLVSMEDEVARGSIILDKGKLMWPPPAKAEPNYFNITLKDAFMY TAGLSGILGLGIASPNPAFATMVTTFGLSGIVGYHTVWGVQPALHSPLMSVTNAISGVTA VGGMLLMGGGYMPNSTSQALATTAAFISAINIGGGFTVTQRMLDMFKRPTDPPEYKYLYG IPAATFLGGYGMCTMGDYPDIHQMAYLAASLCCVGALTGLSHQSTSRIGNTLGMIGVASG VAATLGLLKPSPELLAQMGGATGLGGLIGLVAAKRIEVTDLPQMVALFHSLVGAAAVLTC VANYMVEQPHFATAADANIVKTALFLGTYIGGVTFTGSLVAFGKLQGLLDSAPLMLPGRH VLNGSLLAANIGAMGYYMMTDDALGLGLLGTTTALSGVMGVTLTMAIGGADMPVVITVLN SYSGWALCAEGFMMNNNLMTIVGALIGSSGAILSYIMCVAMNRSLPNVILGGYGTSSTGT GEAMKFEGEATFVQPDDTVSMMTEAQNIMIVPGYGLCVAKAQYPIAELVTLLRDKGKNVR FGIHPVAGRMPGQLNVLLAEAGVPYDIVNEMDEVQDDMDNIDLTLVIGANDTVNSAAEED PNSIIAGMPVIRVWLSKQVVIMKRTMGVGYAAVDNPVFFKENTAMLLGDAKKTCDTLLTK TR------------------------------------------------------FYAA EESEFCERQCCGPHRGFIMHVMDNFGNEVLRATREFVCCAGCCWFACCGYEIRVEAPVGI TIGFIKQKFIRAHFDVMDELLKLTGPFCICECPCC--DIDFNLTTDEIGKVNKQWTGLVK EMFTEADNFGINFPMDLDVKVKATLMGAVFLINMMFFENNQQANEREMQQFLQMEQQKAQ YHQAISKLMDTCWDRCMDRPRDKMDYRTETCFTNCVERFVDTTLILTGRFQQMLQRSVMN RSEGLVQRRNVAKEEEDHDSKETRLTLMEEVLLLGLKDREGYTSFWNDCISSGLRGCILI ELGLRGRIELEKTGMRRRSLLNRKIICKSDAPTGDVLLDESLKHIKETQPPEPAQSWIEY LSGETWNPLKLKYQLRNVRERLAKNLVEKGVCTTEKQNFLLFDMTTHPLTDNTIKQKLVK RVQDSVLSRWVNDPQRMDRRVLSLIYLAHASDVLENAFAPLSDDDYEIAMKRVRELLDLD FEAETLKDGANELMWCIISAFSK-KILKETNEENCEVCVKFIRKFADGLDKIQDEFKKVC SKAKKSENRFCYYVGGTEDSATSILGEITKPISWSMPAENICLKVYKRDQQICDLKYEKQ IDLANTNLSKLKVRELKKILSDWEETCKGCTEKTDYVKRIEELMPIYAPDSVPEDILKGF KLNWMNLRDADSGKVLWQASDDLSQPEQEHEARVPKKILKCRAVAREINFSSKEQMERFR LEQRVLFKGKCLEEWYFEFGFVIPDSTNTWQSIIEAAPENQMMPANVLNGNVMIETKFYD GDMLVSTSKVRIFYVMPKVVSRSVVCTDTKDQEEYQGEKPLYVYYCICGQMSLILDCPME KLPMRRRDNARVIDSNKHAHKLTCEVDETIHIRRPGGIERQFRQKCKKCGLLLYYRHQNQ ITFIVD------------------------------------------------------ ---------------------------------------------LARQCSRVATQHQKR GYADMAFTFACPTEVNVKQVDVPSFSGNFGILPEHVPLLAVLKPGVVTVYEQDGTKKDVF VSSGSVTINDDASVQILAEEAISVDKLDPQAIRDGAAKATQELSSEVDKARAEIAVECYE ALQKAV------------------------------------------------HEPHIC ENILEYNVHAERKGSLRYGKGMSETMSTLHGLVNKGVKVELGIPYELWDKPSAEVTKMHR ACF-------------------------------------FAPTDVTSESDVKSALAAKD KFGRLDVTVNCAGIGVAYLTYNANKDNVHSLEDFQRVLMVNTAGSFNMIRLSAQMMSKNE PDSDNHRGVIINTASVAAYDGQRGQAAYSASKGAIVGMTLPIARDLAAVGIRVNTIAPGL FNTPLLAQLPEKVKKYLASTVPFPARLGHPEEYAHLAQCIVESPMLNGECIRLDGAIRQR DFHFRVQGRNSSAQEKLSHDYPVVDHTYDAVVVGAGGSGLRAAFGLAREGFKTACITKLF PTRSHTVAAQGGINAALGNMEQDCWEYHFFDTVKGSDWLGDQDAIQYMCEEAPTAVIELE NFGMPFSRLDDGKIYQRAFGGQSLDFGKGGQAHRACCVADRTGHSMLHTLYGRSLHYETD YFIEYFALDLLMDQGKCVGVIALSMEDGNIHRFHANNTVLATGGYGRTYFSCTAAHTCTG DGTAMVSRAGLANEDMEFVQFHPTGIYGAGCLITEGCRGEGGYLINSEGERFMERYAPTA KDLASRDVVSRSITLEIREGRGVGPEKDHTFLQLSHLPPDQLNKRLPGISETARIFSGVD VTRDPIPVLPTVHYNMGGVPTNYNGQVIQCNGQDVVVPGLYASGEAACVSVHGANRLGAN SLLDLVVFGRAAALHIASTSKPGDKVPDNNPNAGEASVANIDKLRYADGSTPTADLRLKM QKAMQNHAAVFRDSASLKEGCEKIDECWEELDLKVSDRGLIWNSDLVETLELQNLMINSK ATIFSAEARKESRGAHSHEDFPDRKDEYDYSKPVEGQKLKTFDEHWRKHTMVFVD-ENGK VKLDYRPVIDKVLDDKKIQTIPPKLRVYMTALTHEEILSNTKTVVQGLDTLKNEHHQILN SLLSSMKTIKKGDTNLVEEKTQLLKKSMETIELGLGEAQVMMALSAHLQTVEAEKQKLRA QVRRLCQENAWLRDELANTQQKLQQSEQRVATLEEEKKHLEFMNEMKKYDGDSPLGFPED DEDGTPSAMAQAASGGYEIPTRLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHD HPDVATMLNILALVYRDQGKYKEAANLLNDALGIREKTLGPDHPAVAATLNNLAVLYGKR GKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEQYYQRALEIYE TKLGPDDPNVAKTKNNLASAYLKQGKYKQ------------------------------- ------------------------------------------------------------ ------------IQALGTECQRHSFGGSTIGARPTTACKRTFTKEQIDAGKLQAGTNKCA SQSMGAVRHIADIKADDLSREGQGIVGLQAGNKGASQSGMSMGSVRHVADIKADDMDKAG QTVIGMQSGSNKGASQSGMSMGGVRHVADIRADDLNREGQSVVGLQAGSNKGASQSGMSF GGTRHGADITAGDMDLGQGIVGLQAGSNQGATQSGMAMGGVRHAGDISAGDMAGQSVVGL QAGSNQGASQSGMAMGGTRHCADNTGAEGEGSGVLGLQMGSNQGATQSGMSYGGRRDI-P SAFSFGIDPISCHAFNKDRTQVALPNNHEVHIYSYNWEKTATLDAHLQRVTGLDWAPESN RIVTCGADRNAYVWPTLVILRINRAATCVKWSPQETKFAVGSGARLISVCYFERENDWWV SKHIKKPLRSTVTSIDWHPNNVLIACGSTDFKARVFSAYIKEVDEKPAATVWGKKMTFGN LMAEFCTSGGWVHSVSFSHGGEKLAWVANDASVNV------------------------- -----------------------DQAKVSAFKHFKNLDKLGAKLTTKHQNTSXQVSIYKG DRARPETISTSGVDGQIVLWNFK----------------------------------SGL GKSTLINSMFLSDLYSAEYPGPSHRIKKTVEVETTQVLLKEGGVQLRLTVVDTPGFGDAV DNSNCWQPIINHIENKYDEFLNAESRVNRKTNPDTRVHCCLYFISPNGHGLKPLDVEFMK RLHDKACIIPLIAKADTLTPDECREFKKTILNEIAQHKIKIYEFDDEEENKQQKKLKDRV PFAVVGSNTVVESAGRKVRGRIYPWGVVEVENLEHNDFIALRNMLIRTHMQDLKDITNNV HYENFRYSKLAEVS---------------------------------------------- --------------------------------------MARRYDTRTTIFSPEGRLYQVE YAMEAIGHAGTCLGILANDGVLLAAERRNTNKLLDEVSYSEKIYKLDEDMCCSVAGITSD ANVLTNELRLIAQRYILQYQEPIPCEQLVSTLCDVKQAFTQFGGKRPFGVSILYMGWDKH YGYQLYQSDPSGNYGGWKATCIGNNSAAAISMLKQEYKEGEMTLQQALDLTIKVFSKTLD TNKLTAEKVEIAQLTRKDGKTITRILSDQEVDALIKVYEEAEAKVEAEKKKNLNEAWERL KSLSLRRQEKLFGAHEIQHFNRDANETMAWIAEKDAVLSTDDFGRDLASVQQLQRKHDGV ERDLAALEEKVRALGDEADRLCQTHPDESEEILNKKAEFEQNWQRLKEKSDMRRKHLDDS YHLHRFLSDYRDLISWIYDMKTIISADELAKDVAGAEALLERHQEHKGEIDAREDSFRNT AEAGQRLLESDHYAMQEVKEKLVTLAEEKTNLLNLWEERRILYEQCMDLQLFYRDTEQAD AWMSKQEAFLSNNDLGDSLDSVEALIKKHEDFEKSLAAQEEKIKALDDFATKLIKNEHYA ADDVAARRDALLHRRNNLYEKSKTRRAQLEQSYKVQMFDRDCDETKIWINEKLKAASDEG YLDPTNLQGKLQKHQNFEAELQANQARIEAVNTTGHELIDADHYAKDQIRERLEEISTLW QQLISQSERKGAKLKEANDQQQFNRNVEDVEVWLSEIEGSLMSEDYGKDLTSVQNLQKKH ALLENDVTSRQDRIDAILQNAEAFVASGHFDADNIKAKQATVVDRYQMLYDPMNAKRQKL GDALRLQQFARDVEDEDDWIREKEPIAASTNRGRDLIGVQNLMKKHQALQAEIAGHESRI DSVCEGGKEMLNEGHFASEEIQNKIQMLQDKWQALKDKGNQRKQDLEDSLQAQQYFAEAN EAESWMREKEPIVGNTDYGKDEDSAEALLKKHEALMSDLEAYRSIIDSLKEQASACKQQE APVVDDLGKECVVALYDYSEKSPREVSMKKGDVLTLLNSSNKDWWKVEVNDRQGFVPAAY VKKIDSSLTASQSNLADEYTISVREKQIEDQYDNLLDLGRQRRDKLEESCKAYQLVREAG ELTQWINDKEAVALTTEVGDDLEQVEVIQRKFDDFQKDLKANEARLVELNTIAERLTAMG QTEAAEKIRIQIEDLNQRWAALQQVTQERAQTLGSAHEVQRYHRDADETKDWIEEKDVAL QSDDFGHDLATVQRLQRKHEGLERDLAALGEKVKELDEVANRLMQTHPDQAQSIYEHQHE INEQWNTLTAKANTRKATL----------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------QSKHQKHQAFESELVANSDRIQAVVAMGQKLID SQQCAGSETAVHERIARLAQEWEQLTTKSSEKSERLQEANRQRMYTAAVKDLEFWLGEAE HMLENDDYGKDLATVQNLVKKHQLLEADVNAHEDRVRDLNEQADGFIKSDVLDTQSIKEK KASINERYENVVTRCQHRRSRLDEANTLHQFFRDIDDEEAWIKEKKLLVGSDDYGRDLTG VQNLRKKHKRLEAELNSHEPTVQEVQDVGEKLMADSNLMTDEIRQRLQQLSDNWDELKSM AHTRGQKLDESLAYQQFAANVEEEEAWITEKQHLLGGDDYGDTLAAVQGLLKKHDAFETD FQVHSDRTGEITKEGDKLISEGNHNADQIAARIVTLKEKLKSLQDAANGRKARLIDNSAF LQFIWKTDVVESWIADKETQIRSDDYGRDLSSVQTLLTKQETFDAGLQAFEKEGIQTITA LKDQLIAANHAQTPAIEKRYNDVITRWQRLLGDSDARKQRLLKLQEQYRQVEDLYLTFAK KASAFNSWFENAEEDLTDPVRCNSVEEIKALREAHEQFKASLSAAEADFNQLAALDKQIK SFNVGPNPYTWFTMEALDDTWRNLQKIIRERDDELAREQQRQEENDILRKQFAQAANAFH NWLTET-----EGSGTLESQLEATKKKAAEVRAQRVQLKRIEDLSVAMEERLILDNRYTE HSTVGLAQQWDQLDQLGMRMQHNLEQQIQACNTSGVSEDSLREFSMMFKHFDKEKSGRLN AHDFKSCLRALGYDLPMVEDGQTDPEFEAILDVVDPNRDGFVSLQEYMAFMISRETENVQ SLHDIEAAFRALTSGEKPYITSQELYANLTKEQADYCVARMRPYEDPKGREVLDAYDYSG FVMDIFINGIQCYQCDSNEDASCPSNRRFDRNVNALVDCSSLEAHTPGTF---------- --------------------------------------------------IDKDDSDNPQ LVSEYVNEIYEYMRELERKDINGRMRSILIDWIVQVHIRFHLLQETLYLTVAIIDRFLQE EVKRDKLQLVGVTSMLIASKYEEMYAPEIADFVYITDNAYTKADIRKMECIILRTLDFNL GRPLPLHFLRRNSKAGEVDATKHTLAKYLMELTIVDYDMVHYHPSEVAAASLCLSMKVLD WCDTLNHYSNYSEKDLMPILQKIAQLVSKKLTAIKTKYTSSKFMRIATIPELKCKVVQDL AARGRSRGRRQNNPSPGPESDLERVFIWDLDETIIIFHSLLTGSYAQRYGKDAPASVSLG LRMEEMIFNLA------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------ASLLSVLG ERQTGQSIRTQNVMAASSIANIVKTSLGPVGLDKMLVDDVGDVTITNDGATILKLLEVEH PAAKVLVELAELQDQEVGDGTTSVVIIAAELLKNADELVKCKIHPTSIIAGFRLACKEAC KYIQEHLTISTDELGRDCIVNAAKTSMSSKIIGSDSDFFSNMVVDAAMAVKTTDSKGS-R YPIKAVNVLKAHGRSTRESVLIHGYALNCTVASQAMVKKVTGAKIACLDFSLQKSKMKLG VQILVEDPTKLDAMRQREADITKDRIQKILATGANVILTTGGIDDLCLKYFVEAGAMAVR RCKKQDLKRIAKVTGGQFVVSMANLEGDETFEASMLGSADEVLQERICDDELILVKGPK- -------------------------ALCVVRRVLESKSVVPGGGAVEAALSIYLENFATS LASREQLAIAEFAKSLLVIPKQLAVNAGQDSTDLVAKLRAYHNTSQTKPEHKDLKWVG-- ------------------------------------------------------------ ---DDQTARLLASKNILNQLAVEGRDLTVEYSIYNIGGSAAHQVALTDDSFPEGDFEVVH GSLNVKWQRIAPGSNVSHAVILRPLKYGYFNFTSAVVSYLPTEEDRTLGYTSAPGQGFIL NFRDYDRKFSPHILDWAAFAVMTLPSLGIPFLLWYSSKVRYDTPKQKKNGVGSHKERTDK YRALLQKIESLKIFVEALVNENVSLVISRQILSELCAQLPKLSDASAKNVSHFALEKVQP RVISFEEQVGLIRQHLANIYERDGNWREAANVLVGIPLETAQKQYSNDYKLNTYLKIARL YLEDEDPVQAEAYINRASLLQSDSQDEELQIYYKVCYARVLDYRRKFIEAAQRYNELSYR SIVAEAERMEALKNALVCTILASAGQQRSRMLATLFKDERCQQLPAYGILEKMYLDRIIR SSDLAEFSTHLQQHQRAVTSDGSSILDRAVIEHNLLSASKLYDNISFEELGTLLEIPPAK AEKIASQMITEERMNGYIDQIDSIVHFEAREALPSWDKQIQSLCFQVNDIIEKISQHNPE WMAKIIEAQSSMKLTEAVVRSYRVAKVFRENTDRINSINYSANGELLISSSDDDSIVIYD CQNGTPKRSLNSKKYGVDLIHFTHAPNTAVHSSTKVDDTIRYLSLHDNKYIRYFPGHAKK VVTLSMSPIDDTFLSGSLDKTIRLWDLRSPNCQGLMHLQGRPVAAFDPEGLIFAAGINSE AVKLYDLRSFDKGPFATFKMQQDKDCDWTGLKFSPDGKLIAISTNGQVIRLLDAFQGTPL QTFVGHQNLKGLPLEASFSPDSQYVFSGSTDGRIHCWSTESGARVAVLNADHTGPVQCVQ FNPKYMMLATACTNMAFWLPQIDEEYLLVERKGEKKNVGFIQLNRPKALNALCDGLMREL STVLDDFDADPEIGCLVLTGSTKAFAAGADIKEMQPLGFPKTYSTNFLNHWSRLADNRKP IIAAVNGFALGGGCEIAMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTKAVGKSKAM ELVLTGDKIPAHEAEKAGLVSKVFPADQLVDEAIKTAEKIAGHSKVIVEMAKEAVNASFE MSLREGLHF------------------------------- >Novocrania_anomala XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXM STYKETGKAPETTIHRIRITLTSRNVKSLEKVCADLIKGAKEKNLKVKGPVRMPTKILRI TTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XMATRISKKRKFVADGVFKAELNEFLTRELAEDGYSGVEVRVTPTRTEIIILATRTHNVL GEKGRRIRELTSVVQKRFSFPEGTVELYAEKVATRGLCAIAQCESLRYKLIGGLAVRQAC YGVLRFIMESGANGCEVVVSGKLRGQRAKALKFVDGLMIHRGEPTNDYAE---------- ----------------------------------------------------SKRGRGGS SGGKFRISIGLPVGAVINCADNTGGKNLYIIAVHGIKGRLNRMPAAASGDMVMATVKKGK PELRKKVMPAVVIRQRKPYRRKDGVFIYFEDNAGVIVNNKGEMKGSAITGPVSKECADLW PRIAAHAGSIRKGKTQTVSLGPQVVEGENVFGVAHIFASFNDTFVHVTDLSGKETIARVT GGMKVKADRDEASPYAAMLAAQDVAERCKTLGITALHIKLRATGGNRTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGG------XXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXVAEVADVKLFGKWSSDDVQVSDISLTDYIAVKEKYSKYLPHSAGRYQVKRFR KAQCPIVERLTNSLMMHGRNNGKKLMAMRIVKHAFEIIHLLTGENPLQVLVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQ--------------------------------- ----------------------MAEQMTLRGTLRGHNDWVTQIATTPTYPDIIVSASRDK TLIMWKLLREGNYGVPQRALKGHGHFVSDVVISSDGQFALSGSWDKTLRLWDLSSGQTTR QFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYPIEEGHCEWVSCVRFSPNT SNPIIVSCGXDKLVKAWN-----------------------------------------D LNEGKHLYTLDGGDEISALTFSPNRYWLCAATGSSIKIWDLEGKIVVDELRQEVISTSAK VPQCISLAWSADGQTLFAGYADKCIRVWQVSMAARXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMATLPMNPKPFL NGLTGKPVMVKLKWGMEYKGYLVSVDGYMNLQLANTEEYIDGALSGNLGEVLIRCNNVLY IRGVEEEDEEGEMKDMSDAEGDDVPAAAAVETTMDNNTALQEVLKTALIHDGLARGLHEC AKALDKRQAHLCVLANNCDEPAYVKLVEALCAEHGINLLKVDDNKKLGEWAGLCKIDKEG KARKVVGCSCVVGKDYGKESQALDTLNEYFKSKRMAAIRKKLVIVGDGACGKTCLLIVFS KDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSI DSPDSLKNIPEKWTPEVKHFCPNVPIILVGNKKDLRNDANTIRDLEKMKQGPVKTEERRH MAENINAFCYLECSAKTKD-----------------------XXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFSASAKIVKPQGEKADEFESSISQ ALLELEMNSDLKAQLRELYITAAKEIDVTGKKAIIVFVPVPQLRDYQKIQTRLVRELEKK FSGKHVVFVAQRRILPKPTRKTRTKNKQKRPRSRTLTSVHDAMLDDLCFPAVIVGKRIRV KLDGSRLIKVHLDKNQQTNIEHKLGTFTAVYKKLTGKDVTFEFPEYV-GRGGFRGGFGGR GRGRGRGRGRGKDGEKEWMPVTKLGRLVKDGKIKSLEEIYLFSLPIKEFEIIDFFLGSAL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDHNGHIGLGVKCSKEVATAIRGAIILAKLSV IPVRRGYWGNKIGKPHTVPCKVTGKCGSVLVRLIPAPRGTGIVSAPVPKKLLGMAGIEDC YTSARGQTATLGNFAXGTYAAIAKTYSYLTPDLWKETVFIKSPYQEFTDYL--MSGGLDA LSLKEEDVTKFLACSTHLGSTNADSQMEQYIYKRKQDGVYIINVKKTWEKLLLAARAIAA IENPADVCVISARPYGQRAVLKFASSTGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDP RTDHQPVTEASYVNIPVIALANTDSPLKYVDIAIPCNNKGAXSIGLMWWLL--------- ------------------------------------------------------------ -------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------DMESLGYVLMYFNRSS LPWQGLKAATKKQKYEKISEKKMSTPVEGLCKGFPAEFSMYLNYCRGLRFEEAPDYMYLR QLFRILFRTLNHQYDYTFDWTMLKQKSAAMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXX-GISRDKWHKRRKTGGRQAPLRKKRKFELGRPPSHTKLAP KRIHTVRTRGGNKKYRALRLDTGNFSWGSESQTRKCRIIDVMYNASNNELVRTKTLVKNC IIQIDAVPFRQWFEAHYTTPLGRKKA-KLSEAKEAVLNKRSKKTLKKYDERKKVAKVEQP LEDQFAT----------------------------------------XXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKWEY KEEHPFEKRRAEGEKIRKKYPDRVPVIVEKAAKARVGDLDKKKYLVPSDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGALYQEHHEEDFFLYIAYSDESVYGMRELRIRKL CLNICVGESGDRLTRAAKVLEQLTGQQPVFSKARYTVRSFGIRTNEKIAVHCTVRGPKAE EILERGLKVREYDLIKNNFSDTGNFGFGIREHIDVGIKYDPGIRIYGMDFFIVLGRPRYN VAHRRVKQSTVGFSHKV---------------------MGIKFLEFIKPFCAVLPEISKP ERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVIMASNRGTLMELGIS PIITSGLIMQLLAGAKIIEVGDSPKDRALFNGAQKLFGMIITVGQSIVYVMTGMYGDPAD IGAGVCLLIIIQLFVAGLIVLLVDELLQXGYGLGSG------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------XXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX MVNVPKQRRTFCKGKKCKKHTLHKVTQYKTGKASLKAQGKRRYDRKQRGYGGQTKAVFHK KAKTTKKITLRLECAECKYRAQMSIKRCKHFELGGDKKRKGQMIQFMGRVIRGQRKGPGS IFKAHTKHRKGAARLRAVDFAERHGYIKGVVKDILHDPGRGAPLARVVFRDPYKYKLRME TFIACEGLYTGQFIYCGKKANLQIGNVLPVGTMPEGTIVCSLEEKTGDRGKIARASGNYA TVISHNPDTKRSRVKLPSGMKKVIPSTNRAMVGIVAGGGRIDKPMLKAGRAYHKYKAKRN CWPKVRGVAMN------------------------------------------------- -XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---RPARCYRYCKNKPYPKSRFCRGVPDP KIRIFDLGRKKAKVDDFPLCVHLVSDEYEQLSSEALEAGRICANKYMVKSCGKDSFHIRI RVHPFHVLRINKMLSCAGADRLQTGMRGAWGKPLGTVAKVNIGQPIKSVPAR-------- ------------------------------------------------------------ ----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGKSSKMLQQINYRMRCTL QDGRTFIGTFKAFDKHMNLILGDCDEFRKVKPKTAKSREEKRVLGLVLLRGENLVSMTVE GPPPADEGMSRVPLPGAGHGPGMGRAAGRGIP-GGGLQGPVRGIGGPSQQSMAPQ----- ----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXLSFAESFGLSGAAAIISKTVAAPIERVKLLVQNQDEMLRTGRLAEPYKGVIDCTM RTYRTEGILPFWRGNLANCIRYFPTQALNFAFKDQIKAMFKMHKTDSYGVKFGKNIASGG AAGAMSLCFVYSLDYTRTRLANDAKASTKRQFNGIVDVYRKTLKSDGFVGLYRGFVISCX GICVY------------------------------------------------------- ---------------------------------------------------------XXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXGGGGQGEKKDDKEKKRKYEPPIPTRVGKKKKKV KGPEAANKLPQVTPHTRCRLKLLKLERVKDYLLMEEEFIRNQERLKPQEEKQEEERSKVD DLRGTPMSVGSLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDQLEPGCSVLLNHKVHAVI GVLSDDTDPMVTVMKLEKAPQETYADIGGLDQQIQEIKESVELPLTHPEYYEEMGHQPP- GVILYGAP---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------XXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXMGDRYNIHSQLEHLQSKYIGTGHADTNKWEWL TNQHRDSNASYLGHFDMLNYFAVAENEAKARVRFNLLEKMLQPCGPPPERPED------- FSGYKIYPGHGKRIVKVDGRVHIFLNGKCAKAQLMKRNPRKISWTVLYRRKHKKGQTEEV AKKRTRRTMKFQRAITGATLTDIMAKRNQKPEVRKAQREQAIRAAKEQQRAKQKAAPRIG GKRMKLNISYPATGCQKLVEVDDEKKLRVFYEKRMAAEVSAESLGDEWKGYVVRISGGND KQGFPMKQGILTAGRVKLLLSKGHTCYRERRSGERRRKSVRGCIVDANLSVLNLVIHQKG EQDIPGLTDNTIP----------------------------------------------- -----------------------------------------------------XXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXANATGPLVTKKV FFDITIGGEKAGRIVFGLFGEVVPKTVKNFYQLAEGT-GYKSSKFHRVIKDFMLQGGDFT RGDGTGGKSIYFADENFELEHYGPGWVSMANAGADTNGSQFFITTVTTSWLNGRHVVFGK VLEGMDVVRKI-------------------------------------XXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKKLQRQLEFLEVQEEYIKDEQKNL KKEYLHAQEEVKRIQSVPLVIGQFLEAVDQNTGIVGSTTGSNYYVRILSTIDRELLKPSA SVALHKHSNALVDVLPPEADSSITMLQSDEKPDVAYSDIGGMDIQKQEVREAVELPLTHF DLYKQIGIXPPRGVLLYG------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------XXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXSRRV--LSDDLKNIEFETSEDVEVTPTFDSMGIREDLLRGIYAYG FEKPSAIQQRAIKPIVKGRDVIAQAQSGTGKTATFSISILQCLDTQVRETQALILSPTRE LANQIQKVILALGDYMSXQCQSCIGGTNVGENIRKLDYGQHVVS---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------XXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-PKRKLHINIVVI GHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKMAAEMGKGSFKYAWVLDKLKAERERGITI DIALWKFETVKYYITVIDAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKNGQT REHALLAFTLGVKQLIVGVNKMDSTEPPYSEARFKEIEKEVGNYIKKIGYNPKAVAFIPI SGWHGDNMMKMSWFK--------------------------------------------- -----------------------------------LTEALPGDNVGFNVNNISVKEIKRG MVAGDSKNKPPRGAETFNAQVIVLNHPGQIHAGYAPVLDCHTAHIACKFAELLEKIDRRS GKKLEDNPKFVKSGDAAIIVLQPSKPLCVEAFSEFPPLGSFAGPDMRQTVAVGVIKSVVF KELTRRKVTKSAQKAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXMTRGTTELGDVTPHNIKQLKRLNQVVFPVSYNDKFYKDVL EVGELAKLAYFNDIVVGAVCCRIDTSENQRRMYIMTLGVLAPYRRYGIGTIILEHVLKIC EKDGNFDNIHLHVQINNDGAIKFYEKFGFEIAEKKANYYKRIEPADAYVLQKTFR-MPKQ IMEIKDFLLTARRKDAKAVKIKKNVKFKVRCSRYLYTLVIQDSEKAEKLKQSLPPGLQVK ELKMSKVSRETLHEAVGIIVGKKRKFTETVELQISLKNYDPQKDKRFSGTVKLKYIPRPK MKVCVLGDQQHCDEARANNVECMSADDLKKLNKNKKLVKKLAKKHDAFLASDSLIKQIPR LLGPGLNRAGKFPTMLTHGESMMGKIDEVKVTIKFQMXKVLCLAVAVGHVNMPADELVSN INMAINFLVSL------------------------XXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXX---SDIQNLTDPFADASKIHIRIQQRSGRKTLTTVQGLSTDFDLKKI VKACKKEFACNGTVVEHPEYGEVIQLQGDQRNNIKDFLKKVNLDEQLKVHGFXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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RLSSIVAKTILQGQRMVIVRCEGINISGSFYRNKLKYLSFLRKRCNVNPSRGPFHFRAPS RVFFRTVRGMVPHKLHRGKEALDRLKVFDGIPPTYDKEKR-------------------- -----------------------------------------------------------D GNADKGKAIFVKKCSQCHTPEKGGKHKTGPNLGGLIGRKTGQAEGFHYTEFNKNKGITWG KDTLWIYLENPKKYIPGTKMVFAGLKKKSERADLIAYLHEATKXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFEAR LVQGSLLKKVLESLKDLLNDASFDCSSTGISLQAMDSSHVSLVSLKLRSDGFDTYRCDRN LTMG-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TAKGKIVAVIGAVVDVQFEDELPPILNALEVAD RKPRLVLEVAQHLGENTVRTIAMDGTEGLVRGNACVDTGFPIRIPVGPETLGRIINVIGE PIDERGEVKTDKYLSIHADAPEFVDMNVAQEILVTG-NVVDLLAPYAQGGKMVCLG---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------MLMPNKVRIAIYEHLFKEGVMVAKKDFNCPKHPELEVRNLHVI KAMQSLKSRGYVTEQFAWRHYYWYLTNEGIQYLRDYLHLPPEIVPSTLKRQSGGQDRQEY RRAGRGDKKADVGAGAT------------------------------------------- --------------------------RTFDTNNDGVLSPEEFLQAMSDNPF------AKR AFHASDVDENGHITEEELQDFL-------------------------------------- ------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-ATQAKVSKTETKNNHETDKEQQ EAIEQIDEVQNEIDRLNEQASEEILKVEQKYNKLRQPHFSARSELIAKIPNFWVTAFVNH PQVSALLNEEDEEALQFLTKVEVQEFEDIKSGYRIKFSFDKNPYFENEILSKEFHLNSSK STTIKWKDGKDLTKKSRKRNHEEQESFFGWFADHGDAGTDELGEVIK------------- -----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXX------CKFKLVLLGDSAVGKTSLVLRFTKEMFMDKHEVTVGAAYQTQS LAIDGVTVKYEIWDTAGQERYHCLAPMYYRGAAAAVVVYDITDYDSFERAKTWVKTLRGT ISGHTVIMLA-------------------------------------------------- ----------MAEYLASIFGTEKDKVNCSFYFKIGACRHGDTCSRLHNKPTFSQTILLVN VYHNPQNSAQIILSDVEVQEHYDEFFQEVFTDIEDKYGEIEEMNVCDNLGDHLVGNVYVK FRKEEDAERAVNDLNNRWFNGNPIRAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKP ISRELRRELYGRNR-------------------------------XXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEVENELLDYEE-D--DTKDVKGTYVSIHSS GFRDFLLKPELLRSIVDCGFEHPSEVQHECIPQGILSMDVLCQAKSGMGKTAVFVLATLQ QLEPVDGQVSVLVLCHTRELAFQISKEYERFSKYLGNVKIAVFFGGMQIRKDQEVLKKKC PHIVVGTPGRILALAKSLNLKNIKHFILDECDKMLEQLDMRRDVQDIFRMTPHEKQVMMF SATLSKDIRPICKKFMQDPMEVYVDDDSKLTLHGLQQHYVKLKDNEKNRKLFELLDVLEF NQVIIFV----------------------------------------------------- ----------------------------------------------------PPCYADLG KDARDVVTKGYHFGLNKLNVKTKTSNGVEFTVDQSSNTDTGKVAGNLETKYKLSDYGTTL IEKWNTDNVLGVEVTIEDQLAIGSKLAFDTSFAPATGKKSGKIKTAYKMDYLHLNCDVDF DFAGPTVHGAAVAGYNGWLAGYQMSFDKSKLTKNNFALGYSHGDFTMHGNVMTXNEFGGS IYHKVRDDIETSVNL--------------------------------------------- ------------------------------DSVREKALIDYRKKLLEHKELEARLKEMRE QLKELTKQYDKSENDLKALQSVGQIVGEVLKQLTEDKFIVKATNGPRYVVGCRRQLDKTK LRSGTRVALDMTTLTIMRHLPREVDPLVYNMSMEDPGSINYSEVGGLSEQIRELREVIEL PLLNPELFQRVGITPPKGCLLFGPPGTGXTLLARGVASQLDANF---------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------MTEN LRTVVAKFYDHYIHDTSKKLKLIDVYLLYIMLTGIVQFAYCALVGTYPFNSFLSGFISCV GSFVLAVCLRVQVNPQNKNEFLGIGPERAFADFIFAHVILHLVVMNFI-XXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXGDTIFGKIVRGEIPTKFIHQDEQCVAFHDISPQAPTHFLVIPK KPIPQLCCDEALLGHLLNVARKVAASESGYRMVINDGPDGAQSVYHLHIHVFGGRQMGWP PXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XGLYFHIPETEKKCFIEEIPDETMVVGNYKVEMLDKTSNQYIPTVAGLGMHVDVKDPHGA VVMSRTYASEGRFT---------------------------------------------- ------------------------------------------------------------ ------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXRLYCKAIFTGYKRGLRNQHESIALLKIDGVFKKKETEFYLGKRCAYVYKA RNKTACPGHEKASKIRVIWGKVTRPHGTSGAVRAKFRRNLPAAAMGRRIRVMLYXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPQNEHIELHRKR HGYRLDYHERKRKKESRLVHEKAEKAKKLRGLKAKLYNKKRYAEKVQMKKTIKMHEEKKT KQKKAESAEKGAVPAYLLDREEQTRAKVLSNMI--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------MAARPLITVYSEKAEPAGTTITLPAVFRAPIRPDVVNFVHTEIRKNSRQAYCV SKFAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAYGNMCRGGRMFAPTKTWRRWHRK VNVNQKRYAICSAIAATAIPALVMSKGHRIEEIPEVPLVIADKIESYQKTKEAVGLLKRF KAWQDI------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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NYGMPFSRKEDGKIYQRAFGGQSLNFGKGGQAHRCCAVADRTGHSLLHTLYGRSLYYDTT YFVEYFA----------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------------- ------------------------------------------------------------ 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TVISHNLETKRSRVKLPSGSKKVIPSTNRAMVGIVAGGGRIDKPMLKAGRAYFKYKAKRN CWPKVRGVAMNPVEHPHGGGNHXHIGKASTVRRDTSAGRK-------------------- -XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXKVTKVLGRTGSQGQCTQVRVEFLDDSNRSIIRNVKGPVREGDILTLLESEREARRL RMTKGTSSFGKRHNKTHIICCRCGGRSYHIQKKTCSKCGYPSSRMRKYNWSAKAKRRRTQ GVGRMKYLKVVFRRFRNGFREGTTPKPKGKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGAYKYLQELYRKKQCDALR FLLRVRSWQYRQLSGVHRASRPTRPDKARRLGYRAKQGFVVYRVRIRRGGRKKPVPKGAT 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX >Ophelia_rathkei MSERKAVIKNADMSEDMQQDAVDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSG------------------------------- ----SGAGIGTVFGSFCIALARNPSLKQQLFQYAILGFALSEAMGLFCLMMAFLILFAL- ------------------------------------------------------------ -TRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADMDQVM QFVEPAKQFAKDSIRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNII V----------------------------------------------------------- ---GCRIRELTSVVQKRFNFPEGTVELYAEKVTTRGLCAIAQAESLRYKLIGGLAVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHS------------------- GVLGIKVKIMLPWDPTGKIGPKRPLPDHVSIVEPKEEQAPAQPYSEHKGGK--------- -------------------------------------GRLNRLPKAGSGDMVMCSVKKGK PELRKKVMPGIVVRQRKSFRRKEGVFIHFEDSAGVIVNNKGEMKGSAVSGPVAKGC---- ----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-GKPRGINAGRKLKNTRRINRWAHKH YNQMHIPSRWK-TPFGKASHATGIVVEKIAVEAKQPNSAIRKCVRVQLKKNGKKITAFVP YDGAINFINDNDEVLVSGFGRSGHAVG------------------------------EAV ATVRTRKFLTNRLLCRKQMIVDVLHPGRATVAKTEVREKLARMYKTTPDVVFAFGFRTQF GGGKTTGFALVYDSLDFAKKFEPICTLVRHGGRKQRKERKNRQKKVRGVKKAKVGS---- -------------------LDQELKIIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDE KEPKRLFEGNALLRRLVRIGVLDESKMKLDYVLGLXLEDFLERRLQTQVFKLGLAKSIHH ARVLIRQRHIRVRKQVVNIPSYVVRLDSQ------------------------------- --MGNMFNKLFSGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIGEAREELMRMLAEDELRD AVLLVFANKQDLPNAMNAAEITDKLGLHSLRQRNWYIQATCATSGDGLYEGLDWLSNQLK NQK-------------------KLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRRKQHMVRMNVLADALKSIGNAEKRGKRQVLIRPCSKV IIRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVALPDLESWTRNL LPSRQFGFIVLTTSGGIMDHEEA---------------------GRGISASALPYSRRVP KHKTLSPSGVVELIVKYAKKGLTESQIGVVLRDSYGIPQVRFLTGRKIHRILKKNGCAPK LPEDLYHMIKKAVTMRKHLEKNKKDIDGKFRLNLKESRIHRLTRYYR------------- ----------------------------------DYIAIKEKYAKYLPHSSGRYQVKRFR KAQCPIVERLTSSLMMHGRNNGKKILAMRIVKHAFEIIHLLTGENPLQVVVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAMWLLCTGAREAAFRNIKTIAECLADELINAAK GSSNSHAIKKKDELINAAKGS--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------KTNHYGHNGFLNCVTVSPDGSLCASGGKDGSAMLWD LNEGKHLYTLDGGEAINSLCFSPNRYWLCAATGPSIKIWDLEGKIVVDELRQEVISSSGK APECISLAWSADGQTLFAGYTDSLIRVWQVSMAA-MREYKLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKVVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKLSRNWNCAFLETSAKSK INVNEIFYDLVRQINRKNPDTMSEEKKDGSEHINLKVTGQDGSVVHFKIKKNTPLRKLMS AYCERTGVKMGSMRFRFDGQPINETDTPSQLEMEDGDAIDVFQQQTGG--ALPLNPKPFL NGLTGKPVMVKLKWGMEYKGYLVSVDGYMNLQLANTEEYIDGCLSGNLGEVLIRCNNVLY VRGVEEEEEDGEMKD--------------------------------------------- AKALDKRQAHLCILANNCDEPMYVKLVEALCTEHGINLIKVDDNKKLGEWAGLCKIDKEG KARKVVGCSCVVVKDYGKETQALDVLNEYFKARKMAAIRKKLVIVGDGACGKTCLLIVFS KDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSI DSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDENTKRELMKMKQEPVRPEEGRS MADKINAYAYLECSAKTKEGVREVFETATRAALQTKKKKKGVMDDFQSAEETAFVVDEVS NIIKESIEGAIGGNAYQHNKVNQWTSNVVEQCLNQLTKLGKPFKYIVTAVIMQKNGAGLH TASSCFWDNTTDGSCTVRWENKTMYCIVSVFGLAIMFSASAKIIKPQGEKPDEFESSISQ ALLELEMNSDLKQQLRELVISGAKEIDVSGKKAIIIFVPVPQLRAYQKIQARLVRELEKK FSGKHVVFIAQRRILPKPXRKTRRKNKQKRPRSRTLTVVQDNILDDLCFPAEIVGKRIRI KLDGSRLVKVHLDK----------------------------------GRGGFRGGFGGR GRGRGRGRGRGKE-DKEWMPMTKLGRLVKDMKIKSLEEIYLFSLPIKEFEIIDFFLGTAL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDYNGHVGLGVKCSKEVATAIRGAITLAKLSV VPVRRGYWGNKLGKPHTVPCKVTGKCGSVLVRLIPAPRGTGIVSAPVPKKLLNMAGIDDC YTSARGKTATLGNFAKATYAAIANTYSYLTPDLWKETVFTKSPYQEFTDYLSK------- ----------------------------------------IINLRRTWEKVLLAARAIAA IENPADVCVISARPYGQRAVLKFASYVGATPIAGRYTPGTFTNQIQTAFREPRLLVVTDP RTDHQPVTEASYVNIPVIALCNTDSPLRYVDVAIPSNNKSRESVGLMWWMLAREVLRLRG TISREVPWEVMVDLFFYRDPEEVEKE---------------------------------- ------------------------------------------------------------ ----------------VVQVYRKKFVIHIERIQREKANGASVHVGIYPSKILIVKLKMDK DRKSILERKAATXK-GKHTEE--SSPSSTSVGSTVRQRKTPASGAGAAGMWRFYTEDSPG IKVGPVPVLVMSLLFIASVFMLHIWGKYTR-XXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXTSKAEFLVNGKYRLIRKIGSGSFGDIYLGINV SNGEELAVKLESHKARHPQLLYESKLYKILQGGVGIPHIRWYGEKDYNVLVMDLLGPSLE DLFNFCGRRFTMKTVLMLADQMIGRIEYVHNKNFIHRDIKPDNFLMGIGRHCNKVFLIDF GLAKKYRDNRTRQHIAYREDKNLTGTARYAGINAHLGIEQSRRDDMESLGYVLMYFNRGS LPWQGLKAATKKQKYEKISEKKMSTPVEILCKGHPAEFAMYLNYCRGLRFEEAPDYMYLR QLFRILFRTLNHQYDYVFDWTILKQKAATTMNAEKLKLRIGGKGTARRKKKVVHRTATTD DKKLQSSLKKLAVNNIPGIEEVNMIKEDGQVIHFNNPKVQASLAANTFAVTGHAENKQIT EMLPGILNQLGAESLS---------------------------------MTRYSLDPENA TKSAKAMGSHLRVHFKNTRETAQAVKKM-------------------------------- ------------------------------------------------------------ ------------------------------------------------KKTGPKPELTEE QKQEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIADIDKEGTGTIDFND FLTMMTQKMSEKDSKEEILKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQEADRD GDGEINEGEFLRIMKKTSLY-GISRDKWHKRRKTGGRQNPLRKKRKFELGRPAANTKIAA RRIHTVRTRGGNKKYRALRLDTGNFAWGSEAXPRDTRIIDVIYNASSNELVRTKTLVKNC IITIDATPFRQWYEAHYASPLGRKKTXK-SDEEEAAINKRSKK----------------- -----------------------------------------------XXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXGSNTESESDDSVPELEEMAAAAGLPEELVSKAKQSRSEKKA RKAISKLGLKQVAGVTRVTIRKSKNILFVINRPDVYKSPASDTYIVFGEAKIEDLSQQAQ MAAAEKFKAEEEVDE----------------------VKALKENDNDMVNAIM------- --------------------------ICEEIAIIPSKKLRNKIAGFVTHLMKRIQKGAVR GISIKLQEEERERRDNFVPETSAIEEVDPDTKEMLKMLELTNIPGLQEKQPIESS----- -----------------------VTVIVEKSPKARVGDLDKKKYLVPSDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGALYQEHHEEDFFLYIAYSDESVYGMKELRILKL CMNICVGESGDRLTRAAKVLEQLTGQSPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAE EILERGLK-------------------GIQEHIDLGIKYDPNIGIYGMDFYVVLARPGFC VAKKRRAQSKIGYKHRVSKEESMK--------------MGIKFLEFVRPFCAVLPEIQKP ERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGIS PIVTSGLVMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMVITVGQSIVYVMTGMYGDPAD IGAGVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVN TGRGTEFEGAVIALFHLLATRTDKVRGLREAFYRQNLPNLMNLMATVLVFGIVIYFQGFR VDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYFISQMMAAKFSGNFFVNLLG TWADVGGGGPARSYPVGGLCYYLSPPETLGHVAEDPFHACLYIMFMLGSCAFFSKTWIEV SGSSAKDVAKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVMADFMGAIG SGTGILLAVTIIYQYFEIFVKEQSEMGGMGTLLF----------------------RYVK SVGLGFKTPREAIDGTYIDKKCPFTGNVSIRGRIFTGLVLKLKMQRTIVVRRDYLHY--- ----------MSVHMSPCFRDVSPGDIVTVGECRPLSKTVRFNVVKVTKGTSNRKGFAKF XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRVIRSQRKGAGS VFKAHTKNRKGAARLRPVDFAERNGYIKGVIKDILHDPGRGAPLAKVVFRDPYKYKLRAE TFVAAEGMYTGQFVYCGKKATLQVGNILPVGSMPEGTIVCCLEEKTGDRGRIAKASGNYA TVISHNPDTKRSRVKLPSGCKKVIPSTNRAMVGIVAGGGRIDKPMLKAGRAYHKYKAKRN CWPK------NPVEHPHGGGNHQHIGKASTVRKDTSAGRKVGLIGARRTGRLRGSKQLTG KAKRTKKVGITGKYGTRYGASLRKDIKKMEVTQHGKYTCSFCGKENMKRRAAGIWTCKSC KKTVAGGAYVYSTTAAAGVRSAIRRLR----------------------------GVPDP KIRIFDLGRKRARVDDFPLCIHLVSDEYEQISSEALEAGRICANKYLVKHCGKDAFHLRV RVHPFHVLRINKMLSCAGADRLQTGMRGAFGKPLGTVARVNIGQVLMSVRARDTHKDKVI EALRRAKFKYPGRQKIYTSDKWGFTKWTREQYEPMRQQGILVPDGVGVQYRPPHGPLKAW MDAQ------------GQCTQVRVEFLDESSRSIIRNXKGPVREGDILTLLESEREARRL R--KGTQSFGKRHTKVHSECRRCGKKTWHIQKRRCARCGFPDKKMRSYNWARKTIQRRGE GTGRMSHKRLVQRRAKNNFRHNTVPK----MVDDRAAAKELDQWVDQLMECKQLTENQVK TLCEKAKEILAKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGRSPDTNYLFMGDYVDR GYYSVETVTLLVALKVRYKDRITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHSNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRC GNQAAIMELDDALKYSFLQFDPAPRRGEPHVTRRTPDYFL-------QELWKKKQTSVMQ FVLRMRTWEYRQLSAVHRCSKPSRIEKARRLGYRAKQGYVTYRVRIRRGNRKRPAPKGVV CGKIKSVGITGLKSAKNYQSVAEETVGRKLSSLRVLNSYWVGQDATFKFFEVILVDPDHT AIRNDPRINWICNSVHKHREMRGLTASGKK------------------------------ ----GIAIGRLSEERKGWRKDHPFGFVARPTKNPDGTLNLMNWECAIPGPKKTPWEGGLY KLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSLLDEEKDWRPAVTIKQILLGIQE LLNEPNIKDPAQAEAYTIYCQNRAEYERRVREQALRFRDPSLGKSSKMLQHINFRMRCTL QDGRIFIGTFKAFDKHMNLILGDCDEFRKVKPKGKGTREEKRVLGLVLLRGENLVSMTVE GPPPAEEGIARVPLPGVPGGPGIGRAMGRGVGGGGGLQGPVRGVGGPSQQHMLPQQGMMR GPPPDQIPSFKLVLVGDGGVGKTTFVKRHLTGEFEKKYIATLGVEVHPLVFHTNRGPIRF NVWDTAGQEKFGGLRDGYYIQGQCAIIMFDVTARITYKNVPNWHRDLVRVCENIPIVLCG NKVDIKDRKVKAKAIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLTGDPNLEFVAMPA LAPPEFDMDPSMAAKYEAELRDAQQTALPDEDEDLSDGIKSYYVSKIEELQLVVSDKTQN LRRLEAQRNELNSKVRMLREELQLLQEQGSYVGEVVKPMDKKKVLVKVHPEGKFVVDLDK NIDINDVTANSRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYDMVGGLDKQIKEI KEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ KFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRLESGSGGDSEVQRTMLELLNQLD GFEPKQNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILRIHSRKMNLTRG IHLRKIAEMMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFELAVAKVMQKDSEKNMSM KKLWKLGFVENFALSGAAAIISKTAAAPIERVKLLVQNQDEMIKAGRLDKPYKGVIDCTT RTFRNEGFWPFWRGNLANCIRYFPTQALNFAFKDQIKVMFKMAKTDSYGVKFAKNIASGG AAGAMSLCFVYSLDYARTRLANDAKTGK-RQFNGLIDVYKKTLKSDGFVGLYRGFVISCV GIIIYRGCYFGFYDTLKPILLGDNSGLLASFALGYVVTISSGLVSYPVDTIRRRMMMTSG EAVKYKGSIDCAVTVIKGEGFMSLMKGAGANILRGV---------------------MAD MSDLDRQIEQLRRCEIIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLK ELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQV YGFYDECLRKYGSITVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRAIDRK QEVPHDGPMCDLLWSDPEDTQGWGVSPRGAGYLFGSDVVQQFNAANDIDLICRAHQLVME GYKWHFNDTVLTVWSAPNYCYRCGNVAAILELDEHLQREFTIFEAAPQEQRGKPQADYFL XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSIGV PIKVLHEAEGHIVTCETNTGEVYRGKLIEAEDNMNCQMSSLTVTYRDGRVSQLENVYIRG SKIRFLILPDMLKNAPMFKKVGAGRGKSAILRAAARGRGRGGRGGPRGGMQNEAGEYVDM YIPRKCSASNRIIGAKDHASIQIN------------------------------------ ----------MVRGPRKHLKRLHAPKHWMLDKLGGTFAPRPSNGPHKLRESLPLVVFLRN RLKYALTYDEVKKILNQRLVKIDGKVRTDKCYPAGFMDVITIEKTAENFRLIYDVKGRFA VHRITPVEAQYKLCRVRKV------------------------VKVNDTVKVMGTKDDEY DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTA GQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADNNIVIMLVGNKSDL RHLRAVPTDEAKAFAEKNNLSFIETSALDSTNVETAFQNILTEIYKIVSQKQIRDSPDDN NVQTIHVAPTDTSGDRKQQKCCMSARYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVK GKNVVVLGVEKKAVAKLQEDRTVRKIALLDDHVALAFAGLTADARILINRARIECQSHKL TVEDPVTLEYITRFIAQLKQKYTQSNGRRPFGLSSLIIGFDGTPHLYQTDPSGTYHEWKA NAIGRSAKTVREFLEKHYTDEVVTEKETIKLALKALLEVVQSGSKNMEVAIMRRGEALKM MDSEEIEKYIAEIEK-----------------GDKKDDKDKKKKYEPPVPTRVGRKKKKM KGPDAANKLPAVTPHTRCRLKLLKLDRIKDYLLMEEEFIKNQERLKPQEEKQEEERSKVD DLRGTPMSVGSLEEIIDDNHAIVSTSVGSEHYVSVLSFVDKDQLEPGCSVLLNHKVHAVI GVLGDDADPMVTVMKLDKAPQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIRPPK GVILYGQPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPS IIFIDEIDAIGTKRYESNSGGEREIQRTLLELLNQLDGFDSRGDVKVIMATNRIETLDPA LIRPGRIDRKIEFPMPDEKTKRRIFTIHTSRMTLAKDVDLEDYIMAKDELSGADIKAICT EAGLLALRERRMEVKNEDFKKAKDNVLYR------------RKPYSPFR-DNKADYALAR VDDLLNWARKGSLWPLTFGLACCAVEMMHFAAPRYDMDRFGVVFRASPRQADCIIVAGTL TNKMAPALRKIYDQMPEPRWVISMGSCANGGGYYHYSYSVVRGCDRIIPVDIYVPGCPPT AEALLYGVLQLQKKIKRMSNVQMWYRKTDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYA NNSNYKNDTMIRKEAYVHKSVMDELKRVIEDSEIMQEDDALWPPPDRVGRQELEIVIGDE HISFTTSKIGSLVDVNQSKDPEGLRTFYYLVQDLKCLVFSLIGLHFKIKPI--------- ----------------------------------------------RKSEIEYYAMLGKT GVHHYNGNNIELGTACGKYFRVTTLSITDPGDSDIIRSMP--MTEYKLVVVGAGGVGKSA LTIQLIQNHFVEEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGF LCVFAVNNGKSFEDINQYREQIKRVKDMDEVPMVLVGNKVDLPSRAVETKQGRQLADSFG IPYVETSAKTRQGVDDAFYTLVREIRKYMGDRYNIHSQLEHLQSKYIGTGHADTTKWEWL TNQHRDSYSSYLGHFDMLNYFSVVENESKARVRFTLMEKMLQPCGPPPERAED---ELCA LSEYRIWPGFGKLFIRRDGRPVYLGSSKAQSLTFQRKKPAKLVWTQAWRRLHKKGLSETN LKK----------AITGATLGDIXAKRNQKPEVRKAQREQAIRAAKEKQKAKD------- ------------------------------YDKRISAEVGADCLGDEWKGYMVRIAGGND KQGFPMKQGVLTAGRVKLLLSXGHSCYRERRSGERRRKSVRGCIVDANLSVINMVII--- --EIEGLTDVRLPLRLGPKRANKIRKLFNLPRHSDVCRAVVRR-VTKYYKAPKITRLLTT ERLRRKKQK--------------------------------------------KVKAKEL RGKKKDDLLKQLDELKTELSQLQVAKVTGGAASKLSKIRVVRKSIARVLTVINQTQKXNL RKFYKPKDL-------------------------------------------------QV FFDIEIGGEKTGRIVIGLFGKTVPKTAKNFKTLAEGTDTYKGSKFHRVIKDFMIQGGDFT RGDGTGGKSIYFADENFKLKHYGAGWLSMANAGKNTNGSQFFLTTKKTEWLDGKHVVFGK VLEGMDVIRTIEKTKTDRDKPEKDVVIADSGSLPVEEPFAVPKEPSEE------LKFTLD LGVAYEDDLIVPKEFLDFLKSSMKVNGKKGNLGSKINLTSKVRVSKRYLKYLTKKYLKKS DILEYLKVIATDK----------------------------DEIKLGGCEGPDAMYVKLV SSDGHEFIVKRDHALTSG-------XPGQFAENETNEINFREIPSHVLQKVCMYFTYKVR YTNSSTEIPEFPIAPEIALELLMAANFLDC-------ELNQHKNAKSLWLSIHDKVYDVT KFLEEHPGGEEVLLEQGGQFSTEAFEDVGHSADARELMQNYLVGEMAEKKASGWTSWLIP LGIAIAAA------MSYMLQHLNNGWQVDQAILAEEERVVIIRFGHDWDPTCMVMDETLY RVAEKMKNFAIIYLVDISEVPDFNKMYELYDPCTCMFFYRNKHIMIDLGTGNNNKINWAM EDEQEFIDIVETLFRGARKGRGLVVSPKDYSTKYRYKKLQRQLEFLEVQEEYIKDEQKNL KKEYLHAQEEVKRIQSVPLVIGQFLEAVDQHTGIVGSTTGSNYYVRILSTIDRELLKPSA SVALHKHSNALVDVLPPEADSSITMLGADEKPDVQYSDIGGMDIQKQEVREAVELPLTHF ELYKQIGIDPPRGVLMFGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVR DVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTVNVKVI MATNRADTLDPALLRPGRLDRKIEFPMPDRRQKRLIFSTITSKMNLSEDVDLEDYVARPD RITGADINAICQEAGMQAVRENRYVVLPKDFEKGYKNNIKKDETEHEFYKSHAPLSLESI RERVVLVLKLYDKIEPEKLKLDSHFMNDLGLDSLDQVEVIMAMEDEFGFEIPDADAERLM RPADVVQYIADKEDI-RRVQTLPDDLKNVEFETSEDVEVTPTFDAMGLREDLLRGIYAFG FEKPSAIQQRSIKPIVKGRDVIAQAQSGTGKTATFSISILQSLDTQVRETQALILSPTRE LAGQIQKVILALGDYMSIQCHSCIGGTNVGEDIRKLDYGQHVVSGTPGRVFDMIRRRNLR TRSIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVCLISATLPHEILEMTSKFMTDPI RILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKM REANFTVSSMHGDMVQKEREAIMKEFRSGSSRVLITTDVWARGLDVQQVSLVINYDLPNN RELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLIMAMRRP FDPAAHELDANFRLTRFADLKGGCKVPQDVLLKLLEGLNQQQESEQSHFQYVAAVPRIGI GMDSCVTPLRHGGLSLVQTTDFFYPLVDDPYMMGKIACANVLSDLYALGVIECDNMLMLL AVSQKMSEKERDVVIPLMIRGFKDLAEEAGTSVNGGQTVVNPWVTIGGVATTVCQPNEFI MPDDAVVGDVLVLTKPLGTQVAVNAYQWLDQPERWNRIKLVVSEDDVRKAYQRAMFSMAR LNKTAARLMHKYNAHGATDVTGFGLLGHANNLARIQKNEVGFVIHNLPIIAKMAAVSKAC GNMFGLLQGHSAETSGGLLMALPREQAAAFCKDVEKQEGYQAWI---------------- ------------VFASLLGTVQAYFIHIDAHAEECFFDKVTSGTKMSLMFEVAEGGFLDI DVKITGPDGKNIYQGERESNGKYTFAAHMDGIYKYCFSNKMSTMTPKIVMFTMDIGEKPK AHHNKLEEMINELTTSLTGVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMT LGQVYYLKRFFEVRRVV----------------------------LVERHNKPEVEVRSS KELLLTPVVISRNEKEKVLIEGSVNSLRISISIKQADEIEKILCHKFMRFLMMRAENFRV LRRKPVQGYDISFLITNFHTEQMYKHKLVDFIINFMEEIDKEINEMKLAVNSRARTSAEE FLKEFSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLV TMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTVGNTFKTLDSWRDEFLIQASPRDPEN FPFVVIGNKIDLENRAVSTKRAQQWCHSKGDIPYFETSAKEAINVEQAFQTVAKNALAQE TEVELYNEFPAEIKLTNDTNKEGCGCTAPFDARFPNTNQSRNCWQNFVDFYRCQKIDDYQ PCDYFKRXFSSLCPADWWEQWSEKMEADAFAGKIMKDYLGKDQRATKDEEPDDKPIQSLD EGDIALLKTYGAGMYHRSIKQTEDDIQAVLKRVNELTGIKESDTGLAPPALWDLAADKQT LQSEQPLQVARCTKIINADSEDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNK YQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIDKLREVVEVPLLHPERFVNLGI EPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMART KKACIIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDT LDPALMRPGRLDRKVEFGLPDLEGRAHIFKIHARSMSVEKDIRYELLARLCPNSTGAEIR SVCTEAGMFAIRARRKMATEKDFLEAVNKVIKAYAKFSATPRYMTYNMGAEKIHINIVVI GHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKXKAERERGITI DIALWKFETAKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQT REHALLAYTLGVKQMIIGVNKMDSTEPPYSEVRFNEIKKEVTQYIKKIGYNPDVVPFVPI SGWHGDNMLNMTWFKHWT------------------------------------------ ------------------------------------------------------------ ---------------------------GQIQNGYAPVVDCHTAHIACKFRELLEKIDRRS GKTLEDNPQFVKSGDAAIVNMVPSKPMCVEAFSDYAPLGRFAVRDMRQTVAVGVIKSVKK RTEGSGRVTKAAQKVELEQLRQEAEQLKNQIREARKAAADTTLAQAAANIDAVGRIQMRT RRTLRGHLAKIYAMHWASDSRYLVSASQDGKLIVWDCYTTNKVHAIPLRSSWVMTCAYAP SGSYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIVTSSGDMTCA LWDIETGQQTTSFTGHTGDVMSLSLSPDMRTFVSGACDASAKLWDIRDGMCKQTFSGHES DINAITFFPNGFAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLG GYDDFNCNVWDTLKQDRAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKIWNMSYAYLF KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES FRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSSSNMFIMLIGNKSDLEARR DVKKEEGEAFAREHGLIFMETSAKTSANVEEAFINTAKEIYQKIQDGVFDINNEANGIKI GPQHSPTNPSSGGGGNQGGGMTRGRTDLGDITVHNIKQLKRLNQVVFPVTYNDKFYKDVL EVGELAKLAYFNDIVVGAVCCREDKADGQRRLYIMTLGCLAPYRRLGIGTVMLQHVLKIC GEDGHYDNVFLHVQVNNDSAIKFYEKFGFEIVERKSNYYKRIEPADAFVLQKTFRK---- --EIKDFLLTARRXSAKSVKIKKNVKFKVRCSRYLYTLVISDREKAEKLRQSLPPGLAVK ELKMTKVPRDTIYEAINNILQKKRKFRETIELQIALKNYDPQKDKRFSGTIRLKHVPKNK -KVCILGDQQHMDEANANNLDCMDADALKKFGKDKKVIKKFAKSFDAFLASDSLIKQIPR ILGPGLNKAGKFPT------------------------KVLCLGVAVGNCEMNEDQLRIN TTLSINFLVSLLKKNWNNIRSLHVKSTMGKIQRIYMADADKLNIDSIIARLLEVRGSRPG KNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKVCGDIHGQYYDLLRLFEYGGFPPES NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKEVMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLNSGRPVTPPRGAAKNK GKMMFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEIEGTNVSTT YITCPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPF ICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDEL PAEFKLYLPVQ--MTDTTIQNLQDPFAEDE-IHIRIQQRNGRKTLTTVQGLSSEFDLKKI VRVAKKEFACNGTVVDHAEYGEVIQMQGDQRQKISQFLVRVGLEDQIKVHGFSAIFNFQS LLTVVLLLICTCAYIRSLAPRLLDKNKEGLIGIFWKCARIGERKSPYVAVCCVAMAFSIL FFTSRRVATTLVRQLPRTATQKGSLGASFVACRNISTTAEISSILEDRILGAASADLEET GRVLSIGDGIARVYGLKNIQAEEMVEFSSGLKGMALNLEADNVGIVVFGNDKLIKEGDIV KRTGAIVDVPVGEELLGRVVDALGNPIDGKGAFTHGLRARVGVKAPGIIPRMSVREPMQT GIKAVDSLVPIGRGQRELIIGDRQTGKTAIAIDTIINQKRFNEGTDEKKKLYCIYVAIGQ KRSTVAQIVKRLTDADAMKYTIVVSATASDAAPLQYLAPYAGCAMGEFFRDNGKHALIMY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSEAFGGGSLTALPVIE TQAGDVSAYIPTNVISITDGQIFLETELFFKGIRPAINVGLSVSRVGSAAQIKAMKQVAG SMKLELAQYREVAAFAQFGSDLDASTQQLLNRGVRLTELLKQGQYVPMDVAEQVAVIYAG VRGHLDKMDPARITEFEAAFVKHMRANHQDIVDDI------------------------- MEAVYSIPFSVLQCPNLKLKKPTWVKTPSPMVVFSMILASYFLVTGGIIYDTIVEPPSIG STTDEKGNSRPVAFMPYRVNGQYIMEGLASSFLFTLGGLGFIILDQTNKPTTPRLNRILM LSVGFMSILVSFFMCRVFMRMKLPMPKVKRSRKPPPDGYELIEPTIDELDAKMREAETDP HEGKRKVEALWPIFRIHHQKTRYIFDLFYKRKAISRELYDYCLKERIADANLIAKWKKPG YENLCCLRCIQTRDTNFATNCVCRVPKTKLEEGKIVECVQCGCRGCSGEYAQVTKMLGNG RLEALCFDSVKRLCHIRGKLRKKVWINQSDIILIGLRDYQDNKADVILKYTPDEARNLKA YGELPESAKINDDQDDNITFEDIDEI---------HETVTVELKNGTQVHGTVTGVDVSM NTHLKAVKMTVKNKDTVQLDSLSIRGNNIRYYILPDSLPLDTLLIDDTPKAKAKK--LQK PKSEMTPEELASREQEEFNTGPLSVLTQSVKNNTQVLINCRNNKKLLGRVKAFDRHCNMV LENVKEMWTEVPKTGKGKKKSKPVNKDRYISKMFLRGDSVILVLRNPL------------ -------------------------------RNKLKYLSFLRKRMNTNPKRGPYHFRAPS KIFWRTCRGMLPHKLHRGKEALERLKVFEGIPPPYDKQKRMVVPSALKVLRLKSRRKFCV LGRLSHEVGWKYQNVVATLKSRRK-----------------------------------A GDATKGKKVFVQRCAQCHTVEAGGKHKTGPNLNGLIGRSTGKAPGFSYTDANKSKGITWG RDTLWIYLENPKKYIPGTKMVFAGLKKTKERADLIAYLEESTKIFVERTLAIIKPDAVSE EIEDIILRSGFTILQKRRVHMTPEQASDFYAEHYGKLFFPSLVAYMSSGPVIALVLAREK AISYWRELIGPTNAIKARETHPDCLRAIYGTDDQRNGLHGSDCYSGGEREVRFFFPDSVV EPIPVGQAARDYLAKAVNPTLLKGLTQLCKQKPRDPVIWLADWLLENNPNKPKV-MFEAR LVQGSLLKKVLESVKDLLNEATWDCNSTGMSLQAMDSSHVSLVSLMLRSDGFDTFRCDRN LSMGINLGSMSKILKCAANDDAVTIKAGDSADTVTFMFESPNGEKVSDYEMKLMDLDTEH LGIPETDYSSVIKLPAAEFQRICRDLSQIGESVVICCTKEGVKFSASGDLGTGNIKLAQT ANVDKEEEAVVIEMQEAVTLTFALRYLNFFTKATPLSSQVSLSMSPEVPLVVEYKIGDMG YVRYYLAPKIEDGDDA-----------------------------------MLNALIVKD RVPKLILEVAQHLGESVVRTIAMDGTEGLVRGNECIDIGSPIRIPVGRETLGRIINVIGD PIDERGPVNSTSFAAIHAEAPLLTEMSVEQEILETGIKVVDLLAPYAKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVINLKDASSKVSLVYG QMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIA ELGIYPSVDPLDSISRILDPNIVGVEHYTIARQVQKILQDYKSLQDIIAILGMDELSEVD KLTVSRARKIQKFLSQPFQVAEVFTGSAGKLVSLQETIKGFKMIVDGELDHLPEVAFYMV GPVEDVVAKAERLAQD-MLMPKKTRVLIYEHLFKEGVMVAKKDYHAPKHPELEVPNLHVI KALQSLKSLGLVTEQFAWRHYYWYLTNEGIQYLRDFLHLPPEIVPSTLKRQ--------- -----------------MGKQNSKLKPEVLEDLRANTEFSDEEIQEWYKGFLKDCPSGHL SVEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFICALSVTSRGKLEQKLRW AFSMYDLDGNGYISRQEMLEIVTAIYKMVGTVMKMPEDESTPEKRTDKIFRQMDKNLDGK LSLDEFIEGAKSDPSIVRLLQCDP-----------------------------------L TGLNEQVPHYRQALDMILDLEPDDELEDNPSQSDLIEQAAEMLYGLIHARYIMTNRGIAQ MIEKWQQGDFGYCPRVYCENQPMLPIGLSDVPGETMVKLYCPKCQDVYTPKSSRHHHTDG AYFGTGFPHMLFMVHPEYRPKRPANQFSPRLYGFKIHPLAYDLQYQAAANFKSSYGNSKR -----------------------VIPLSTYMKTYRRGDIVDIKGNGAVQKGMPHKXYHGK TGRVYNVTQHAVGVVVNKRVRGRIIAKKVNLRIEHVAHXKCRQEFLTRVEANEKKKREGR AEVNTRRQPVPPRKSHFVRT-----------------------EDVSPPEPSLDINSITD RAADKAFVSEIVQGMALVLSHMFKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAICPAQAITIEAETRSDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEY STETHEELLYNKEKLLENGDKWEAEISSNLQADHLYR-----KVAKPESKNNHEADKEQQ EAIEQIDEVQNEIDRLNEQASEEILKVEQKYNKLRQPYFGKRSELIAKIPNFWVTAFVNH PQVSALLNEEDEEALQYLTKVEVQEFEDIKSGYKINFNFDDNPYFENKCISKEFHLNSSK STPIKWKTGKDLTNKSKKRSHEEQESFFSWFSDHGDAGADELGEVIKDDIWPNPLQYYLA SEIDEEEAEEEGLDEEE-----------------------ALFYGNAFIVSAIPMWLFWR IHQMDLYILFGVVTLITTYLVAFAYKNVKFLLKHKIAQKRGDAVSREVM------KKMTK QEKDERILWKKNEVADYEATTFSIFYNNAMFLLFIIIASFYILRTLSPIVNY-------- -------------QGKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQT VCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVKELQRQ ASPNIVIALAGNKADLRMVEYEEAQAYAEENSLLFMESSAKTAMNVNDIFLAIAKKLPKN EQGVNLSQES-----------EKDKVNCSFYFKIGACRHGERCSRLHNKPTFSQTTVMQN LYINPQNSAQITMNDVEGQEYFDDFFEEIFTEMEDKYGEIEEMNVCDNLGDHLVGNVYIR FRYEEDADKSVADLNNRWFNGRPIHAELSPVTDFREACCRQYEMGGCTRGGFCNFMHLKP ISRELRRELYGRGRRSRSRSPPNKRSRSRSPSRERRRSRSRERSGMFLTRSEYDRGVNTF SPEGRLFQVEYAIEAIKLGSTAIGIQTAEGVVLAVEKRVTSPLIEPASIEKIFEVDGHIG CAMSGLIADSRTMIDRARVEAQNHWFTYNEKMSIESVTQAVSNLALQFGDDDADPGAMSR PFGVALLFAGIDEKGAQLYHMDPSGTFIQYDAKAIGSGSEGAQQALQEVYHKSMTLKEAR KEVLKILKQVMEEKLNAVNVEMATVTPENNFVMCSKEEIEEVIKDIAQKTWEMSNSMESV STIDEIYRYDKKQQQDILTAKPWEKDPHYFKHIKISALALLKMVMHARSGGNLEVMGLLL GKVDGNTMLVMDSFALPVEGTETRVNAQAQAYEYMAAYTESAKQVQRLENAIGWYHSHPG YGCWLSGIDVSTQMLNQQFQEPFVAIVMDPVRTISAGKVNIGAFRTYPKGYKPPDEGPSE YQSIPLNKIEDFGVHCKQYYSLEISYFKSSLDKKLLESLWNKYWVNTLSSSSLLTNADYT TGQMFDLADKLEQSEGQLGRGTYMEKKSEDKLAKATKDACKNTIESIHGLMSQVIKDKLF NQV--LPRRIIKETQRLKQEPVAGIEATPDEQNARYFHVVVMGPKDSPYEGGVFKLELFL PEEYPMSAPKVRFMTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPD DPLANDVAEQWKHDEVQAIETARQWTRMYA---NELLDYEEEEEQEAKEVKGTYVSIHSS GFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVVCQAKSGMGKTAVFVLATLQ QLEPVDGQVSVLVLCHTRELAFQISKEYERFSKYMNSVKIAVFFGGMPIKKDEQVLKTNC PHIVVGTPGRILALAKSLNLKNLKHFVLDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMF SATLSKDIRPVCKKFMQDPMEVYVDDDSKLTLHGLQQHYVKLKDNEKNRKLFELLDALEF NQVIIFVKSVQRCMALAQLLVEQNFPAIAIHRAMTQEERLNRYQQFKDFHKRILVATNLF GRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDEGDAKV-------- -------SSDLNYGFYKLESKTKTRNGVEFTTNGSSNHDSGKFNGSLETKYKWSDYGLTF LEKWNTDNTLGTEITIEDQLVKGLKLSFDTQFAPQTGKKSGKIKTAYKQEHVNTNCDVDF DFAGPTINGAAVVGYNGWLAGYQMAFDKSKLSKSNFAVGYTKDDFTLHTSVNDGSEFHGS IYQRVNDELETGVQLNWTAGSNATKFGLSAKYCPDKESSFRAKVNNSSQIGLSYQQKIRD GVNMTLSSLIEGKNFNQGGHKVGVGIDFEADSVREKALQDYRKKLLEHKELEARLKEMRE LLKDLTKQYDKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQIDKSK LKAGTRVALDMTTLTIMRYLPREVDPLVYNMSVEDPGAISYSEIGGLGEQIRELREVIEL PLLNPELFARVGITPPKGCLLYGPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIGES ARLIREMFGFARDHQPCIIFMDEIDAIRRFSEGTSADREIQRTLMELLNQMDGFDALGQV KMIMATNRPDTLDPALLRPGRLDRKIEIPLPNEQARMEIIKIHANPIAKHGEIDWEAVVK LSDDFNGADLRNVCTEGGMFAIRAERDYIIEEDLMK--------------------MQDN LKTVVSRFYNEYMQSTPKKLKIIDAYLFYILMTGGLQFLYCCMVGTFPFNSFLSGFISTV GCFVLGVCLRIQCNPQNKSDFYSLSPERAFADFCFAHIILHLVVINFIGSLASPSQLLPL ELVDKCIGSRIHIIMKNDKEIVGTLMGFDDFVNMVLEDVTEFESTPEGRRVTRLDSILLN GNNITMLVPGGEGPEVIDHYENPRNVGSMDKKSKKVGTGLVGAPACGDVMKLQIEVDDSG KIVDAKFKTFGCGSAIASSSLATEWIKGKSIDEAGTIKNQDIAQELCLPPVKLHC----- ----------------LVLVLGDIHIPHRNNSLPAKFKKLLVPGKIQHILCTGNLCTKES FDYLKTLASDVHVVRGDFDENMNYPEQKVVTVGQFRIGLCHGHQVVPWGDVASLAMLQRQ LDVDILITGHTHKFEAFEHESKFYINPGSATGAYNPLDSGVVPSFVLLDIQQSTVVAYVY QLNGEDVKVERIEYKK----------VIMLTGKYAGKKAVILKVYYEGSKSRKFGHVLVA GISKYPRKVTKRMSEERVSRRIRIKPFVKYVNFNHFMPTRYVLQHVDVKQV--------V LRRKARREAKAKFEERYKTGKNRWFFQKLRFERTFIMIKPDGVHRGLVGDIIKRFEQKGF KLVAMKFMWAAEEHVKKHYTDLSSKPFFPDLVKYINSGPLVPMVWEGGVVATGRKMLGAT NPADSEPGTIRGDYCIEVGRNICHGSDAVASAEKEIALWFGKDDLVSWRPADDDWVYETD APKPVKTTGKSKEKALKAKKSVLRGVNAKRQRKVRTSVHFTRPKTLRLPRAPKYPRKSTP RRNRLDQYKIIKY---------------------------------VKKLYDINVFKVNT LIRPDGEKKAYVRLAPDYDALDVANKIGIIMPSKQRMRLANEKMAKNVNARGGVPKTLKQ AEDKLPVGPWLLGLFIFVVCGSAVFQIIQSIRMVRIKGWTAVATWRWVANDENCGICRMP FDGCCPDCKIPGDDCPLVWGQCSHCFHIHCIVKWLNSQQVHQLCPMCRQEWKFKEMIRFI LIQNRAGKTRLAKWYMHFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKVVYRRYAGL YFCICVDVADNSLAYLEAVHNFVEVLNEYFHNVCELDLVFNFYRVYSVVDEMFLAGEIRE TSQTKVLKQLLMLSSLEKPTIFSKIIDKSIPADIVYEDNECLAFRDVNPQAPTHILIIPK KVIPGISEDQQILGHMLLVAKTVAADNTGYRLVINDGPDGAQSVHHLHVHLLGGRQMEWP P-GGLLSYFSNLFGSKERRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVQYKN LKFQVWDLGGQTSIRPYWRCYFSNTDAIIYVVDSMDRDRIGISKQELVSMLEEDELKKSV LCVFANKQDIEGAMTVTEVANALGLSAIKNRKYQIFKTSAIKGEGLDEAMEWLANTMQNT KGLYFHIGETEKKCFIEEIPDETMVVGNYKVEMFDKMQNTYVPTIPGLGMHVDARDPDDR IIISRTYAAEGRFTFTSHAAGEHVICLHSNSSAWFGGGQLRVHLDIQVGEHANDYQQIAA KDKLTELQLRVRQLLDQVEQITKEQNYQRYREERFRQTSESTNQRVLWWSIAQTLILLVT GFWQMRHLKGFFEAKKLVILFQVSLEHEILLHPRYFGPNLLNIVKQKLFSEVEGTCTGKY GFVIAVTTIDNIGAGIIQAGRGFVVYPVKYKAIVFRPFKGEVLDAVVTQVNKVGLFTEIG PLSCFISRHSIPADMEFDPNSNPPCYKTKDEDIVIQQDDEIRVKIVGTRVDASDIFAIGT LMDDFLGLVSRLYVKAVFTGFKRGLRNQHENTTILKVDGVSSKEETSFYLGKRCCYVYKA QRKTACPGHDKPSRLRVVWGKVTRSHGNSGCVRATFKRNLPPKAMGRRIRVMLYMAKKTY DLLFKLLLIGDSGVGKSCLLFRFSEDAFNTTFIPTIGIDFKIKTVELGGKKIKLQIWETA GQERFHTITTSYYRGAMGIMLVYDITNLKTFENISKWLRNIDEHANEDVEKMILGNKCDM EDKRQVQKEKGDLIAREHSIPFLETSAKSNINVEKAFMDLAQAILNK------------- ------------------------------------------------------------ ---------------------------------------------------------EVF KVIKTGKSKRKAWKRMVTKVTYVGEGFTRKPPKFERFIRPMALRFKKAHVTHPELKATFC LPIIGVKKNPTSPTFTSLGVITKGTVIEVNVSELGLVTTSGKVVWGKYAQVTNVPENDGC INAILLVMAARPLISVYSEKGETTENNVTLPAVFRAPIRPDIVSFVHSEMRKNGRQPYAV SEKAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRR INTNQRRYALCSAIAATGIPGVVMSKGHRIEQIPEVPLVISDKIEEIKKTKEAVGVLRKV KAWSDIEKVKASKRFRAGVGKLRNRRRIQRRGPLVIYNKDNGICRAFRNIPGITLLNVAR LNLLKIAPGGHVGRFCIWTESAFKSLDNLYGTWKKPSEEKSNYNLPMPVMTNSDLSRLLR SDEIQKVIRPPKKDKHRRVLKKNPLKNLRHMMRLN------------------------- -----------------------------------------------------VGAGGKK SRLLLAMSTAAEFRDHLTEFSEHYASLGPPNPDNLPEDGKLKSEVMVKDNRRYYLDLKEN QRGRFLRVSPRSQQRSQIAIPAQGMIEFRDALTDLLDEFGTDDHEGQGELPEPRSMRVEN KMFYFDVGQNRRGVFMRISETNFRTAITIPERSWGRFRDILSDFVDK--------QMRAT VNQKLIESGERERLKELLRTRLVECGWRDQLKAQCKEIVRQRGLEHITVDDLVAEITPIG RGLVPDQVKKELLQRIRTFLAQQSSMNVRNAKPEDLMNMQHCNLLCLPENYQMKYYFYHG LSWPQLSYVAEDEKGKIVGYVLAKMEEDPEDSVPHGHITSLAVKRSHRRLGLAQKLMDQA SRAMVECFNAKYVSLHVRKSNRAALHLYAQTLRFQISEIEPKYYADGEDAYAMRRDLYEF ADK-MSHTILLVQPGRKPEGRTYSDYESVNECLEGVCKIYEEYLKRMNPQSPSITYDISQ LFDFIDQLADLSCLVFEKSSGKYLPHNKAWIKEKIYILLGKQAGKMAEEGTEKKETETKR VVHTYPLIRHSDMNEEMRTEAMELCVTACEKFTSNNENAAKMIKETMDKKFGASWHAIVG EGFGFEITHEVKNLLYMFFGGNYAIVIWKCS----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------TQMKLLKKRQKKAHVMEIQLNGGTISQKVDWAREHLEKAMPIGE VFARDEMIDIIGVTKGKGFKGVTSRWHPKKLPRKTHKGLRKVACIGAWHPARVGFSVARA GQKGYHHRTEINKKIYRMGQGIHQKDGKVIKNNAXTDYDLTEKTITPMGGFPHYGEVNND FVMIRGCCIGSKKRCLTLRKSLLVHTKRVALEKVNLKFIDTASKFGHGRFQTHLEKQTFM G-----MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLG LWDTAGQEDYDRLRPLSYPQTDVFLICFSLISPASFENVRAKWYPEVSHHCPNTPIILVG TKLDLREDKETVEKLKEKKLSPITYPQGLAMAKEIQAVKYLECSALTQKGLKTVFDEAIR AVLCPKPKPKKKKVCRLLIFDSSLKKKKKKKTPFDLDAAMEEISLDDLLAKKKKKKKKVF EFDDISEALPKDTDSLPSKKKKMDSDRDYTYDELLKRVFDIMREKNPDMVAGEKKRFVMK PPQIMRVGTKKSAFANFADICRMLHRQPKHLLAFLLAELGTSGSLDGNNQLIIKGRFQQK QIESVLRSYIKEYVTCHTCRSPETILQKDTRLYFLQCETCGSRCSVASIKSGFQAVTSKR AAIRAKT-FDDAVEERVVNEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGK DYSLHRLILGTHTSDERNHLLIASVQLPNDNAQFDASHYDSEKGEFGGFGSVSGKIEIEI KINHEGEVNRARYMPQNPCVIATKTPSSDVLVFDYTKHPSKPDPSGECHPELRLKGHQKE GYGLSWNPNVNGNLLSASDDHTICLWDINTTPREGKCIDAHTVFTGHTSVVEDVSWHLLH DSLFGSVADDQKLMIWDTRSNNTSKPSHTVDAHTAEVNCLSFNPCSEFILATGSADKTVA LWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGE------- ------------------------------------------------------------ ---MPAPSRARVYADVNTHRPREYWDYEAHVVEWGQQDDYQIVRKLGRGKYSEVFEAVNV TNNEKCVIKILKPVKKKKIKREIKILENLRGGTNVITLLAIVKDPVSRTPALIFEHVNNL DFKQLYQTLTDYDIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLA EFYHPGQEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPFFHGHDNY DQLVRIAKVLGTEELFEYIDKYQIDLDPRFNDILGRHSRKRWERFVHSENQHLVSPEALD FLDKLLRYDHQERLTAREAMGHPYFAPIVKE---------------KNHEKRKLMFKRAE KYIKEYRIKERDDIRMSRQARKHGNFYVPAQAKVAFVIRIRGINGIHPRPRKVMQLFRLR QINNGVFVKLNKATIQMLRLAEPYIAWGYPNLKSTRELIYKRGYGKLD------------ ----GKYGIICVEDLIHEIFTAGPAFKHASNFLWTFKLNTPIGGWRKKNNHYVXGGDFGN REDKVNALLKKMMQFMLLFSRQGKLRLQKWYEAHPDKVKKKITRELITTILARKPKMCSF LEWKDLKIVYKRYASLYFCCCVQQGDNELLTLEIIHRYVELLDKYFGNVCELDIIFNFEK AYFMLDELLLGGEVQETSKKNVLKAIAAQDLLQEETPQGFFEDHGLG------------- -KRLTLKLNGGRVVTGTLRGFDPFMNLVIDETMEDCKSGEKNSIGMVVVRGNSIVLLESL DRIEFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTI RLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFQQTSKWIDDVRTERGSDVIIM LVGNKTDLSDKRQVSTEDGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMEQTEQ KKMIEVKLKDTPAEPQQ------------------------------------------- -------YEKRTMELLRISKDKRALKFCKKRLGTHLRGKRKREEMQDQIVKMRKAMVDAA TKKNLAKIPLLKTKAGPRDGDLWVQRLKEEYQSLIKYVQNNKESDNDWFRLESNKEGTRW FGKCWYIHELLKYEFDVEFDIPVTYPTTAPEIALPELDGKTAKMYRGGKICLTDHFKPLW ARNVPKFGIAHAMALGLGPWLAVEIPDLISKEIISHKQFLDNFDFLDDVRRMNARQLYYQ ALNFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFYRGDLLFLTNKEEEHIRVGE IVVFKVEGREIPIVHRVLKVHEKENGSLKFLTKGDNNQVDDRGLYAPGQLWLQKKDVVGR AKGYVPYVGIVTILMNDYPKFKYAILALLGLFVLIHREMSTMNPEYDYLFKLLLIGDSGV GKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYR GAHGIIVVYDVTDQESFNNVKQWLQEIDRYANEHVNKLLVGNKCDLTTKKVVDYTTAKEY ADQLGIPFLETSAKNATNVEQAFMTMAAEIKNRMGPVPTAPNVKITDSTPVKSSGGGCC- --MKSEVLRMGNDEVTSRTRLLDNEIKIMKSEVMRISHELQAQKDKIKENGEKIKVNKTL PYLVSNVIELLDVDPQDQAEEDGANVDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDPEQL KPGDLVGVNKDSYLILETLPAEYDSRVKAMEVDERPTEQYGDIGGLDKQIQELIEAVVLP MTHKERFETLGIQPPKGVLLYGAPGTGKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGA KLVRDAFALAKEKAPAIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPSSD IKVIAATNRVDILDPALLRSGRLDRKIEFPTPNEEARARIMQIHSRKMNVSHDVNYEELA RCTDDFNGAQCKAVCVEAGMIALRRGASELNHEDYMDAILEVQAKKKANLNYYAKDAADQ NFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRQDKRVKLQIWD TAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDNAQVVLVGNKC DLEDERVVSTERGKQLADQLGLEFFETSAKENINVKAVFERLVDIICDKMSESLDSDPTQ TKRLTENPNPPDGGCQC--THGMAVTRDYISQPRITYKTVSGVNGPLVILDGVKFPKFAE IVKLTLQDGTKRAGQVLEVSGSKAVVQVFEGTSGIDAKHTTCEFTADILRTPVSEDMLGR VFNGSGKPVDKGPSVLAEDYLDIMGQPINPWSRIYPEEMIQTGISAIDGMNSIARGQKIP IFSANGLPHNEIAAQICRQGGLVRLPGKSVMDDHSDNFAIVFAAMGVNMETARFFKQDFE ENGSMENVCLFLNLANDPTIERIITPRIALTTAEFLAYQCEKHMLVILTDMSSYAEALRE VSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRSGSITQIPILTMPNDDITHPIPDLT GYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRDDHADVSNQLYACYAIG KDVQAMKAVVGEEALTAEDLLYLEFLIKFEKNFIAQGPYENRTIFETLDIGWQLLRIFPK EMLKRIPAEKLAKYYPRDASGPGFVGIKFCQECNNMLYPKEDKENKLLLYACRNCDYQQE ADNPCIYVNKIQHEVDALTQIIADVVADPTLPRTEDHPCPKCGHKEAVFFQSQSKRAEEG MRLYYVCTLPACMHRWTEKPAYKVADLTLAEWGRKAIEIGENEMPGLMMMRKVYGPSKPL KGARIAGCLHMTVQTAVLIETLIELGAEVTWSSCNIFSTQDHAAAAMAKAGVPIYAWKGE TDEEYMWCVDQTILFPDGKPLNMILDDGGDLTNLVHEKYPQYLEGIKGLSEETTTGVHNL YKMMAAGKLKVPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGKVACVAGYGDV GKGCATALRAFGARVLVTEIDPINALQAAMEGYEVTTIELAVPEARIFVTTTGCKDILKG EHFSNMMEDTIVCNIGHFDCEIDVKWLNENCASKENIKPQVDRYTMKNGRHLILLAEGRL VNLGCAMGHPSFVMSNSFTNQVLAQIELWTNTAKYPLGVHFLPKKLDEEVANLHLGHLGA KLTKLSDDQATYLGIPQEGPFKPDHYRYTEEQEQQPTNTVEEPLDLIRLSLDERTYVKMR NDRELRGRLHAYDQHLNMVLGDVEETVTTMEIDEETYEEIYKTTKRNIPMLFVRGDGVIL VSPPMRTMSTSNVENFSPQTIRQVAKELSDLQKEPPEGIKVLLNEEDITDIQANIEGPAG TPYAGGFFRVRLVLGKNFPSEPPKGFFLTKIFHPNVAKNGEICVNTLKKDWKAEYGIKHI LLTIKCLLIVPNPESALNEEAGKLLLEQYEDYSTRAKIYTEIHARP-------------- ---------------------SCAFGSTKYFALCGLGGILSCGTTHTLLVPLDLVKCRIQ VNPEKYGGIIKGFKVSVREAGIKELAKGWAPTFFGYSMQGLCKFGFYEVFKVFYSDLIGE ENTYLWRTSLYLASSASAEFIADIALCPMEAVKVRIQTSPGWANTLREGVPKLMKEEGYW GFYKGIVPLWGRQIPYTMMKFACFERTVEALYKFVVPKPRSDCSKAEQLVVTFVAGYIAG VFCAIVSHPADTVVSKLNQMKGASFIGIAKDLGWAGMWKGLFPRIIMIGTLTALQWFIYD GVKVYLHLPRPPPPEMPESLKKKLQHWTNERYIALALLPIIPTALAFVMDTVLCGIFLHT YWRLSGVCEDYIHVTVLAFGSMCYFNYTDVGFANAARMLYSQL----------------- --AETLLISEVQRKQQNESAEEEQELSEVFMKTLNYTQRFSKFKNRETITAVRSLLMQKK LHKFELASIANLCPDSAEEAKALIPSLEGRFEEDEMQQILE----------TLQPHLAKQ DLDNLDVAKLTPLTPEVISRQATINIGTIGHVAHGKSTLVKAISGVQTVRFKNELERNIT IKLGYANAKIYRCDDPKVPRPQCYTSRGSSHPDEFPCDLPGAQKYKLVRHVSFVDCPGHD ILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILIMQNKIDLVKESQ AQEQYEQIIRFVQGTIAEGAPVIPISAQLKYNIDAVCEYIVNKIPIPPRDFTSEPRLIVI RSFDVNKPGCEVDDLKGGVAGGSILSGVLKVGQEIEVRPGLVSKDKDGKLKCQPIFSRIV SLFAEQNDLQFAVPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIYIELEINYFLLR RLLGVRTEGDKKAAKVQKLSKNEILMVNIGSLSSGGRILAVKADLAKVGLNSPVCTQVGE KIALSRRVEKHWRLIGWGQIRRGVSVKP-------------------------------- ---ISKQKKVELVQIKDSQALIRARFLRENGRYLPQQAVLMRKNFFNNEQTGYFQKNPMT DPSMMTDMMKGNLTNVLPMIVVGGWINWQFSGFLTTKVPFPLTLRFKPMLQRGIELGTLD ASWVSSASWYFLNVFGLRSMYSLILGQDNSADQTRIMQDQMTGAAMGMPPDPSKAFKAEW EALEITEHQWALVGVEDEIMMFIFDWFSGILSYLGLYKKSGKLVFLGLDNAGKTTLLHML KDDRMAQHVPTLHPTSEELQMGGMRFTTFDLGGHKQARRVWKDYFPAVDGVVFLIDVFDR ERYAEAKAEFDSLLTDELIVNAPVLILGNKIDIPGAASEDEMRHYFGLHGQTTGKGTIPR SELRPMELFMCSVLKRQGYGEGFRWLAQYINILRRNPPGTRAIQWCHWPDDSFEEMDSTL AVQQFLQQAIRRDFSNIDEILTPPEGQDEGVWKYEHLRQFCMELNGLAVKLQFECNPETC TQMTATEQWIFLCAAHKTPKECPAIDYTRHTLDGAACLLNSNKYFPSRVSIKESSVAKLG SVCRRVYRIFSHAYFHHRGLFDEYEHETALCKRFTTFVTKYNLMSKDGLIVPILEDQMPN IKLQSSDGEIFPVDVEIAKQSVTIKTMLEDDEDEEEAVPLPNVNAAILKKVIQWCTYHKD DPPPPEDDENKEKRTDDISSWDAEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMI KGKTPEEIRKTFNIKNDFTPAEEEQVRKENEWCEEK------------------------ ---------------------RTIGTKIASDGLKGRVFEVSLADLQNDEYSFRKFKLVAE DVQGRNVLTNFHGMNMTTDKLRSMVKKWQTLIEANVDAKTTDGYLLRMFCI--------- ------------------------------------------------------------ --------------DLGKLMEMHGEGTSAVTTEGGEKVDRPDNYEPPVLATVMSASAVYI LDIKGKVLICRNYRGDIDMSAVDKFMPLMMDREEDGNVTPIIQHGENTFIYIKYNNLYLV ATSKKNANVALVFQFLHKIVQVFCEYFKELEEESIRDNFVIIYELLDELMDFGFPQTTDS KILQEYITQEGHKLEVAPRPPMAVTNAVSWRSEGIKYRKNEVFLDVIESVNLLVSANGNV LRSEIVGAIKMRVYLSGMPELRLGLNDKVLFESTGRGKSKSVELEDVKFHQCVRLSRFEN DRTISFIPPDGEFELMSYRLNTHVKPLIWVESVIERHQHSRVEYMIKAKSQFKRRSTANN VEILIPVPQDADSPKFKTTAGSCKYAPDQNVVIWTIKSFPGGKEYLMRAHFSLPSVIGED SEGKPPIHVRFEIPYFTVSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRTQMGILEK ISEIESEMARTQKNKATSAHLGLLKARLAKLRRELIEPKGGGGGTGEGFDVAKTGDSRIG FVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGCIKYKGAKVQLLDLPGIIEGAKDG KGRGKQVIAVARTCNLIFIVLDVLKPLQHKKLIEHELEGFGIRLNKDPPNIGYRRKDKGG INLTATVAQSELDSDLVKTILGEYKIHNADITLRNDATTEDIIDVIEGNRVYVPCVYVLN KIDQISIEELDIIYKIPHCVPISAHHKWNFDDLLEKMWTYLALVRIYTKPKGQLPDYNSP VVLKEGVSTVEDFCNKIHKSIMKEFKYGLVWGSSVKHQPQKVGKDHLLNDEDVVQIVKKM AKHHPDLIFCRKQPGVAIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGSYQGRCVIC GGPGVSDAYYCKECTIMEKDRDGCPKIVNLGSAKTDLFYERKKYGFKKRPNLPPISGDRL TARTQIRKIPVPANRYTPLKENWMKIFTPIVEHLKLQVRFNLKSRNVEIKTCKDTTDIGA LQKGADFIKAFTQGFEVEDALALVRLDDLFLESFEITDVKPLKGDHLARAIGRVAGKGGK TKFTIENVTKTRIVLADSKIHLMGSFQNIKIARTAICNLILGSPPSKVYGNMRAIASRSA ERRIKVAKPVVELDGDEMTRIIWADIKEKIIFPYLDLEALYYDLGLPHRDATNDQVTIDS AEAIKKHSVGIKCATITPDEERVEEFNLKKMWLSPNGTIRNILGGTVFREPIICKTIPRL IPGWTQSIVIGRHAHGDQYKALDFVAKGPGKFEMMFTPSDGGEQRFEVFDFK-ASGVGMG MYNTDESINGFAHSCMQYALKKKWPLYLSTKNTILKRYDGRFKDIFQEIYEADYVKEFES NGIWYEHRLIDDMVAQGLKSSGGFVWACKNYDGDVQSDVVAQGYGSLGLMTSVLMCPDGK TIEAEAAHGTVTRHYREHQKGNATSTNPIASIFAWTRGLEHRALLDNNPDLTRFCQVMEK ACVDTVDSGKMTKDLAGCIYGLKNVKPEHYLYTSDFLEAVKEEFDMGKLLSKIFGNKEMR ILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWR HYYTGTQGLMFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMKPHEI QEKLGLTRIRDRNWYVQPSCATTGDGLYEGLTWLTSNAKSFGDLSSDNGLEALNCHLASR SYIIGYTPTLADTSVYKSLK-PTTRYTHILRWHNHITSFGKDIETFSGTQQIQDQPASGA ASETKDDDDFDLFGSEAERVKNERLEAYAAKKSAAVIAKSSIVLDVKPWSDETDMAELES SVRSIQTDGLLWGASKLVPLAYGIKKLQISCVVEDDKVGTDFLEEEITKFEDHVQSMDIA AFNKIKVQEVREVTRIERIGAHSHIRGLGLDDALEARVVSQGMVGQTSARRAAGIILEVI KEGKIAGRAVLIAGHPGTGKTAIAMGMAQALGQDTPFTAIAGSELFSLEMGKTEALTQAF RKSIGVRIKEETEIIEGEVVEIQIDRPATGTGAKVGKLTLKTTDMETIYDLGQKMIESLT KEKVAAGDIITIDKATGKITRLGRSFTRARDYDAMGANTKFVQCPEGELQKRKEVVHTVS LHEIDVINSRTQGFLALFSGDTGEIKAEVREQINAKVAEWREEGKAEIVPGVLFIDEVHM LDIECFSFLNRALENDMAPVMIMATNRGITRIRGTNYKSPHGIPIDLLDRLLIISTTPYE EKEMKQILQIRCEEEDVEMSEDALTVLTRIGMETSLRYSIQLITTAMLCCRKRKGAEVSV EDIKRVYSLFLDESRSTQFLKEYQQEFMFHEMAKFDLTTRMGQYLDRHLVFPLLEFLSVK EIYDEKEMLKGKLDLLSNTNMVDFAMDVYRTLYPDSEVPLSLKDKRSEVVSELKRLQQET DPIIKIFENEDVQIQSARDGRQLFEFLQKQFDFQPEMVNTLYRYAKFQYECGNYSGAAEY LYFVRVLLPPSDRDYMNALWGKLASEILMQDWDNALDDLNRLKEVIDSSLQSLQQRTWLI HWSLFVFFNHQKGRDLIIDMFLYQPQYLNAIQTMCPHVLRYLTTAVITNKTVLKDLVKVI QQESSTYRDPITEFLECLYVNFDFDGAQQKLRECETVLVNDFFLVACLDDFIENARLFIF ETFCRIHQCISINMLAEKLNMPPDDAERWIVNLIRNARLDAKIDSKLGHVVMGTQAISPY QQVIEKTKGLAFRSQMLVMNIEKKLGSKAMGVEVICQTPGDGKTFPQNGNTVIVHYTGTL ANGSKFDSSRDRNKPFEFKIGQGQVIKGWDEGVAKMSVGERSTLKISPDYAYGDKGVGGV IPPNAELTFDVELLGLK-----CDYCDTYLTHDSPSVRKTHCNGRKHKENVSVYYQKWLE EQVQKLVDDTTAAFKAGGSNNK-------AVPPPSQSGGGMPGP-MPMMGP-PPGPMPPM RPPMGPMGPMMPMQMRPEPLTLERDVQRALELLEQLQKSGEFQKLQALQKVLQSEFCNAV REVYEHVYETVDITGSPEVRANATAKATVAAFAASEGHAHPRVVELPKTEEGLGFNVMGG KEQNSPIYISRIIPAGVADRHGGLKRGDQLLSVNGVSVEGEPHEKAVDLLKAAQGSVKLV VRYTPKVLEEMEARFDGQRTARRGQ---LAAVVIADPTVHFKEEFWDSRWVQSTHKGAEA GDFKWTAGKFYND-ENDKGIQTSQDAKFYGLSAKFDKPFSNEGKDLVIQFTVKHEQNIDC GGGYVKVFGSDLDQKDMHGETPYNIMFGPDICGPGTKKVHVIFNYKGKNLLTKKDIRCKD DVFSHLYTLVVRPDNTYEVKIDNKKVESGDLEADWDFLPAKTIKDPDAKKPDDWDENETI DD-----------------------------------------PEYKGEWKPKQIPNPAY KGKWVHPEIDNPDYSPDDALYKYDDIGAIGFDLWQVKSGTIFDNVLITDDEKHAEDVGEN TWGKAKDGEKKMKDAQDEEDRKKREEEDKKRKEEEEE-------MDSSMPEPSLYTVKAI LILDNDGNRLIAKYYDDTFPTVKEQKNLFNKTHRANAEIIMLEGLTCVYRSNVDLFFYVM GSSQENELILVSVLNCLYDSVSQMLRKNVEKRALLENMDGVFLAIDEICDNGIILESDPN AVCQRVAFRSDDIPIGEQTVASVLQSAKEQLKWSLL-MNIFRLCGDLSHLLAIILLLLKI WKTRSCAGLSGKSQIMFALVFTTRYLDLLTSFISVYNSVMKTFFIVSSFGTVYLMYHKFK ATYDSNHDTFRMEFLIVPVAGLAFLVNHDFSPLEILWTFSIYLESVAILPQLFMIGKTGE AETITSHYLFALGSYRGLYILNWIYRFYFEGFFDLIAVVAGCVQTILYCDFFYLYVTKVW KGKKLTLPA--IEEVKSTTKTQRIATHSHVKGLGIDENGFAHQSAAGLVGQEHAREAACV VVEMIKSKKMAGRAVLLAGPPGTGKTAIALAMAQELGSKVPFCPMVGSEVYSAEIKKTEV LMENFRRAIGLRIKETKEVYEGEVTELTPVETENPMGGYGKTVSHVVIGLKTAKGTKQLK LDPSIYESLQKEKVEAGDVIYIEANSGAVKRQGRSDTFATEFDLEAEEYVPLPKGDVHKK KEVIQDVTLHDLDIANARPQGGQDIISMMGQLMKPKKTEITDKLRKEINKVVNKYIDQGI AELVPGVLFIDEVHMLDIECFTYLHRALESTIAPIVIFATNRGKCTIRGTDDLVSPHGIP LDMLDRLLIIRTLPYSQEEMQQIIRIRAQTESISVSDESLQLLGEIGVKTTLRYAVQLLT PAFLLTRINGKDTVSQEEIEEINELFFDAKSSAKILAEQADKFMKEFEVDEEGDKGIVKL KEQVKKRKGRGF-TKTEVEDYEGMEVGGPGPQRSVEGWILFITSVHEEAQEDDIIDKFAD HGEIKNLHLNLDRRTGFLKGYALVEYETFAEAHAAMENLNGTEILGQKINVDWSFVRGPQ KK-MTYQLYRNTTLGHTLQESLDELIQCGQITPQLALKVLLQFDKAINTALATRVKNRVT FKGKLNTYRFCDNVWTFVLNEVEFRTVDKVKIVACDGR-TFLFTSESVGEGHPDKICDQI SDAVLDAHLKQDPNAKVACETAAKTGMIMLLGEISSKATVDYQKVVRDTIKYIGYDDSSK GFDYKTCNVLSALEEQSPDIAKGVHMGRDEDDIGAGDQGLMFGYATDETEECMPLTVVLA HKLNAKIAELRRSGELAWARPDSKTQVTCEYRMENGACIPTRCHTIVISIQHSEDVTLEQ LRKDLQKQVVEVVIPARYLDDRTVFHLQPSGRFVIGGPQSDAGLTGRKIIVDTYGGWGAH GGGAFSGKDFSKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVAEPLSIFVSSYGT GVKPDIELLKIINKNFDLRPGRIVKDLDLKRAIYQKTASYGHFGRAEFSWEVPKELVY-- GSALKRLMAEYKQLTLNPPEGIVAGPINEENFFEWEALITGPEGTCFEGGIFSARLVFPS DYPLSPPKMKFACDIFHPNIYPDGRVCISILHAPGDDPMGYESSAERWSPVQSVEKILLS VVSMLAEPNDESAANVDAAKTWRDDRAKFDEIAHRTVRKSLGIMRLEKCYFCSSTVYPGH GTTFVRNDCKVFRFCRAKCHKGFKKKRNPRKVKWTKAFRKTAGKELSVDPSLEFEKKRHV PVKYDRELWSKTVKAMKRIEEIKVKRQNQFIMNRLKKGKQLRKHQDIKDVKENIHLLKSP AAN---YTVVMIRHGESTWNQQNKFCGWHDADLSELGVQEAKSAGKMLKEKGYTFDIAYT STLKRAIKTLYYVQDELDLHWIPVVRHWRINERMYGALQGLNKSETAAKHGEEQVKIWRR SYDTPPPAVDRSDERWPGNDPKYALVDKQLIPRAECLKDTVERALPFWYDVIVPSILKGE KVVIAAHGNSLRAMVKYLDNMSDADIMALNIPTGIPLVYELDKDLKPIKHYYLADEAQVK AALEKVAAQGKAKMEQQDIFYNKAEYIETASGNKVSRQSVLCGSQNIVLNGKTIIMSDCI IRGDLANVRIGRHCIISRRAVIRPPFKKFSKGVAFFPLHVGDHVFIDEDSVINAAQVGSY VHIGKNCVIGRRCVLKDCCSIADNTVLPPETVVPPFTLFNGSPGMSFLFGSRNAKTFKPK KNIPEGTHQYDLMKHAAATLGSGNLRMAVQLPEGEDLNEWVAVNTVDFFNQINMLYGTIT EFCTEESCPVMSAGPKYEYHWADGTTIKKPIKCSAPKYIDYLMTWVQDQLDDEALFPSKI GVPFPKNFLGIAKTILKRLFRVYAHIYHQHFQQVIQLQEEAHLNTSFKHFIFFVQEFNLV DRRELAPLQELIDKLSGKD---------------------------------ILARRTNA KFNKIVLKRLFMSKTNRPPLSIARLVRLLKKPGRENKMAVVVGTITDDLRIFEIPKMKVC CLKVTERARSRILRAGGEIITFDQLALRASKGQNTLLVQG--------------PGVPKS STKPLVRSKGRKFERARGRRSSRGFKN--------------------------------- --------------------------------------VIEVVNEFITELETSGQALEHI HSNEVIRTVEAFLKKKFQVIVVEYHGQQVATNLAKAGIETTVITDSAVFAMMSRVNKVII GTHTVMANGGLKAVGCQAIALAAKHYSTPLIVCAAMFKLSPEYMCSYEDAFNKFVSPQDI LNPVFDYVPPELVTLYISNIGGNAPSYVYRLLSELYHMIIPIRCFTCGKVIGNKWEAYLG LLQAEYTEGDALDALGLKRYCCRRMLLSHVDLIEKLLNYAPLEKKSPEAIEGRKHIDVQT ELYLEELSDRVEEADVEVQTDAFLDRPPSPLFVPAKTGVDFATQILEGELFDFDIEVKPI LEVLVGKTIEQSLLEVMEEEELANLRCQQREFEELRNAELVEQQRLEEQERRHREEKERR MKQQKEILRKESETSDKIAARAFAQSYLADLVPSVFGTLSDNGYFFDPVERDVEQGFMPW LMDCVSEQLNKSVLGRTVLDALIREVVAQRREQY------GLLKEYKVIGRMMPTDKNKT PPLYQMRIFAPEPITAKSRFWYHVSLLKKMKKSQGEVLLCQQVFEKRPLVIKNFGVWLRY DSRSGSHNMYREYRDLTTASAITQCYRDMGARHRARTGTIQIMKVETVPASKCRRSNIKQ FHDSHIKFPLTHRVSKRLHTPRFTTRRPHTYFSAQDQMKEFWKKNQGRPSSPWVIYRPHL PMLTSLTHRITGIAMGVALYGVSIGTFVAPGDFAGYIEFIKGLEISPMLLFPAKTIVAFP LVYHYINGIRHLAWDFGKGYELATQYKTGWTILASISY-------------YHKGSRYEQ EKLLLDSTTLYIGNMSYYTTEEQVYELFGRAGDVKRVIMGLDKYKKTPCGFCFVEYYTRD DAESCVRYVNGTRLDDRIVRTDWDAGFKEGRQYGRGKSGGQVRDEYRADFDAGRGGYGGL VQQKLKPNYTLKFTLAGHTKAVSSVKFSPNGEWLASSAADKLIKIWGAYDGKFEKTVSGH KLGISDIAWSSDSKLMVSASDDKTLKIWDIATGKCLKTLKGHSNYVFCCNFNPQSNLIVS GSFDESVRTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG KWIVSGSEDNAVYIWNLQTKEIVQKLQGHTDVVLCCACHPSENIIASAALENDKTIKLWR SDV----------------------------DDSKIGGNASSGVDIVLAGKKDYMTYIKG YMKLVKE------LGLLRWEKPFMYFFKHGLDAEKVMAVEFADGVVFGADSRTTTGSYVA NRVTDKLTKVTDQIYCCRSGSAADTQAIADIVNYHLNIHKIEMGEPPLVKTAATVFQDLC YNYRDQLSAGIICAGWDKQLGGQVYSLSLGGSLIRQPISIGGSGSTYLYGYVDAVFKEGM SKEACMEFVLNALTLAINRDGSSGGVARMACITKDGVERKTILHPDLPKMVMIAIAAVLI MICCCXCICKKCCKRGKGKDAKKGLKGAVDLKSVQLLGNAYKEKVQPDLDELEVNMEDNE DAESTKSVEKLGKLQFSLDYDFQKGELSVGVIQGADLPGMDMSGTSDPYVKVYLLPDKKK KFETKVHRKTLNPVFNETFTFKVPYAEMGAKTLTFAVYDFDRFSKHDQIGQVRVPLNSVD LGRVVEEWRDLQCPESDAEKENKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSD PYVKLSLMLNGKRIKKKKTTIKKCTLNPYYNESFTFEVPFEQIQKVTLIVTVVDYDRIGT SEPIGRVVLGCNSSGTELRHWSDMLANPRRPVAQWHTLQEMPEKNMVLADLGRKITTALR SLSSATVINEEVLNSMLKDICAALLEADVNIKLVKKLRENVRAVIDFDEMAAGLNKRRMI QSAVFNELVKLIDPDVKAWTPTKGKNNVIMFVGLQGSGKTTTCTKMAYYYQKKGWKTCLV CADTFRAGAFDQVKQNATKARIPFYGFMTKGSEQESMARLKKLMTIMDS----------- ----------------------KDSELDSHE--GAKLFTRARGMRVARGAGVSQREVTEL ITQKFAQMVKKMGGIKGLFK-GGDMSKNVPAQMSRLNQQMARMMDPRVLQQMGGMSGLQN MMRQFQQGAMSILAYNGAAVIAMKGKDCVAIASDRRYGIQAQTVAMDFQKIFEMGPRLYV GLPGLATDVQTVAQRLQFRLNLYELRENRQIKPKTFMSMVSNLLYERRFGPYFVEPVIAG LDPKTCEPFIASLDLIGCPMVTDDFVVSGTCTEQMYGMAESLWEPDMEPDVLFEKISQAL LNAVDRDAGSGWGAVVHIIEKDKVTTRTLKARMDMTSKDYYFDSYAHFGIHEEMLKDEVR TLTYRNAMYHNRHLFKGKTVLDVGCGTGILCMFAAKAGAAKVIGIEMSSIVQYAEQIVKA NKLDNVITLVKGKVEEVTLPDGVEKVDIIISEWMGYCLFYESMLGTVLYARDKWLAPDGL IFPDRATLYICAIEDRTYKDEKINWWDSVYGFDMSCIRKVAISEPLVDVVDPKQVVSNSC LVKEVDIYTVKEEDLTFRAPFHLQCRRNDYVQAFVTFFNIEFTKCHKRTGFSTGPEARYT HWKQTDDFITVKKGEEIFGHFGIKPNKMNNRDLDFNIEVDFKGELSEMVEENHYKMR--- ------------------------------------------------------------ ------------------------------------------------------------ --LGPEKTSFFQALAIPTKISKGTIEILNDVKXIKAGDKVGASEATLLNMLRISPFKYGL QIEQVYDSGTVFDPSVLDLTDEDLRSRFMQGVANVAGLSLAIGYPTVASAPHSIVNGFKN LLAIAAETDVTFKEA-----SAMKGKLIAVIGDEDTCTGFLMGGIGELDKHRRPNFLVVD KNTPVNEIEESFKQFSNRDDIATILVNQNIAEMIRHVLDIYTQPIPAVLEIPSKDHPYDA SKDSILRRAKGMFSAEDFRGNEASLPMELCSNFDADEIKRLGKRFKKLDLDNSGSLSVDE FMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGISQFSVKGDKESKLRFAFKIYDMD KDGYISNGELFQVLKMMVGNNLKDAQLQQIVDRTIIHADTDGDGKISFEEFCAVVGTLDV HKKMVVDVMTYLNSWEEFSKAAERLYVSDPNKCRFIIKYKHSEGQLYVKITDDHVCLQYR SEHAQDVKKLEKLTSQLMRHMASKELYEEVKLYKTAREREKYDNMADLYAVINTLQVLEK AYIKDSVTPKEYTAACSKLLVQYKAAFKQVQGDEFPDVEAFMKKCKLDCPAALERIKEDR PITIKDDKGNTSKCIADIVSLFITIMDKLRLEIRAMDEIHPDMRDLMDTMNRLSILPADY VGKGKVYTWLGTLGQMQASDELTDAQVRQLLFDLESAYGEFNRILHSMLSAMVKEHQTKQ LIRKDLQERRKKEASNATALTHALVDHLNAGVAQAYVNQKKLDTETKILQVNANQFARQT SQWLQLVEDFNQSLKEIGDVENWSRTIETDMRTVSNALEYAYK----------------- --------------------------------------------------QRVVFLKQLA SGLLLVTGPYHLNGCPLRRINQIYVIATKTKVDVSGVTLPERLNDEYFKR---------- -------------SDERKEDQLTVDKQVLDSIRKNPDKKLLFGYLGAMFSLKNREAPHKM IFLEWLFGKKKTPQEMLRQNQRALNKAMRDLDRERQKMEQQEKKVIADIKKMAKQGQMDA VKIMAKDLVRTRRYVKKFILMKANIQAVSLKIQTLKSNDAMAQAMKGVTKAMATMNKQLK LPQIQKIMMEFEKQSEIMEMKEEMMNDAIDDAMGDEDDEEEGEAIVSQVLDELGLQMADQ LSDLPAAGKTDAKQPVGISEADADLEARLENLKRQSKYCDFCLGDETENKKTGQKEVLVS CADCGRSGHPSCLQFTPNMIISVKKYPWQCIECKSCGLCGTSDNDDQLLFCDDCDRGYHM YCLNPP--------------------TLERTSSLYPLTNYTFGTKEALYEKDASVAERFR RMREEFAKSGMRRTAEGVLIVHEHGLPHMLLLQLGTTFFKLPGGELIPGEDQVEGLKRLL TEMLGRQDQPAVDWVIEDTIGNWWRPNFEPPQYPYIPAHITKPKEHKRLFLVQLPEKALF AVPRNYKLVAAPLFELCDNAAGYGPIISSLPQSLSRFNFIY------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------VEGREIISNLAKAAGLATMISTMRPDIDNMDEYVRNTTARA FAVVASALGIPSLLPFLKAVCKSKKSWQARHTGIKIVQQIAILMGCAILPHLKNLVEIIE HGLVDEQQKVRTITALALAALAEAATPYGIESFDSVLKPLWKGIRTHRGKGLAAFLKAIG YLIPLMDAEYANYYTREVMLILIREFQSPDEEMKKIVLKVVKQCCATDGVEPQYIKDEVL PPFFKHFWNQRMALDRRNYRQLVDTTVEIANKVGAAEIISRVVDDLKDEAEQYRKMVMET IEKIMANLGAADVDSRLEEQLIDGILYAFQEQTTEDVVMLNGFGTVVNALGKRVKPYLPQ ICGTILWRLNNKSAKVRQQAADLISRIAIVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLG SILGALKSIVNVIGMTKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGAEFVS AREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVC TTVAIAIVAETCSPFTVLPGLMNEYRVPELNVQNGVLKSLSFMFEYIGEMGKDYVYAITP LLEDALMDRDLVHRQTAMSAIGHLALGVYGFGCEDSLTHLLNCVWPNIFETSPHVVQAFM NAVEGIRVGLGSSKILQYSMQGLFHPARKVRDVYWKVYNTCYIGAQDAMVPAYPRISNDE KNMYERYELDYLLDDFMVDDEEYDLEYSEDSNSEPDVDLENQYYNSKALKEDNPGAALEN FQKVLELEGKDKGEWGFKALKQMIKINFKLGKFDEMMARYKQLLGYIKSAVTRNYSEKSI NSILDYISTSKQMELLQNFYETTLEALREAKNDRLWFKTNTKLGKLYFDREEWAKLQKIL KQLHHSCQTDEGEDDLKKGTQLLEIYALEIQMYTEQKNNKKLKALYEQSLHIKSAIPHPL IMGVIRECGGKMHLREGEYEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGIN PFDSQEAKPYKNDPEILAMTNLVSAYQNNDINEFEKILKTNRRNIMEDPFIREHIEDLLR NIRTQVLIKLIKPYTRIHIPFVSNELNIDVSEVENLLVSCILDNTIHGRIDQVNQVLELS TGIARYNAMDKWTGQLASLHLAIVNKM-VLLMGKSGSGKTSMRSIIFANYIARDTRRLGA TIDVEHSHVRFLGNLVLNLWDCGGQEAFMENYFASQRDNIFRNVEVLIYVFDVESRELEK DMHYYQSCLEAILQNSPDTKVFCLVHKMDLVQEDQRELIFREREDDLQRLSKPLATSIWD ETLYKAWSAIVYQLIPNVHQIETNLSNFATILDADEVLLFERATFLVISHCQRRQHQDVH RFEKISNIIKQFKLSCSKLAASFQSMEVRNSTFAAFIDIFTSNTYVMVIMSDSDIASAAT LINIRNARKHFEKLERVDGILSFSTRLFSVLRFESVIHEFDPYFNYRTTRFLTEEGFYNF HNWFDDRAWYPLGRIIGGTIYPGLMVTSAALYKALHFFNITIDIRNVCVFLAPLFSSFTV VITFIFTRELKDTGAGLVAAAMIAIVPGYISRSVAGSYDNEGIAIFCMLLTYAMWIKSVK TGSVFWSVICALAYFYMVSSWGGYVFLINLIPLHVLALMLTGRFSHRIYVAYSTVYCIGT ILSMQISFVGFGPVQSSEHMAALGVFGLCQIHAFIDYIRSKLSREQFNILFRSLVLFSSV IIGTALGKISPWTGRFYTLLDPSYAKNNIPIIASVSEHQPTTWSSFYFDLQMLVFLFPAG LYFCFKNLTDANIFIIMYGVTSIYFAGVMVRLMLVLAPVMCILAGIAVSATLTTYMKNLD TSKKADANYPIKNEIATGVVLMMSLFLMTYTFHCTWVTSEAYSSPSIVLSARAGDGGRII FDDFRESYYWLRHNTPEDAKIMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMAS TEDKAYEIMRELDVDYVLVIFGGLTGYSSDDINKFLWMVRIGGSTDRGAHIKEQDYYTAQ GEFRIDKEGSPTLLNCLMYKMCYYRFGSVYTEASKPTGYDRVRNAEIGHKDFELDVLEEA YTTEHWLVRIYKVKDLENRGNKINVRPLVRLVCKRFFGDSTGFTSMCVQHIPSPLANARQ KVENIYTGPLDTELAEAMCECDPEGPLMVHTTKLYPTHDATTFHVFGRVISGTLYANQDI RILGENFSLQDEEDSRFSQVGRLWITEARYNVEVNRVPAGSWVLIEGIDQPIVKTATLTE ASGNEEVYIFRPLKFNTSSVIKIAVEPVNPSELPKMLEGLRKINKSYPLIATKVEESGEH VVLGTGELYLDCVMHDLRKMYSDIDIKVADPVVSFCETVVETSSLKCFAETPNKKNKITM IAEPLEKGLAEDIENEVVQISWPRKRLGEFFQTKYDWDLLAARSIWAFGPDTTGPNILVD DTLPSEVDKGLLGSVKDSIVQGFQWGTREGPLCDEPIRNTKFKILDAVIAPEPIHRGGGQ VIPTARRVAYSAFLMATPRLMEPYFFVEVQAPADCVSAVYTVLARRRGHVTQDAPVPGSP LYTIKAFMPAIDAFGFETDLRTHTQGQAFCLSVFHHWQIVPGDPLDKSIIIRPLEPQPAT HLAREFMIKTRRRKGLSEDVSINKFFDDPMLLELAKQDVMLSYGMQEVFSLFDNKGDGKV YSHQLGDVLRAMGQNPTEAEVKKCQDPDHRINFEQVLPIYATISKNRDTSPVEDFVEGFR VFDKEQNGLINSAELRHLLTSLGEGLSEEEVSELLQGLEDAQGNVNYEEFVKMVMS---- LSFNMNHGYLEALVRGFKCGVLKQTDYLNLVQCETLEDLKLHLQSTDYGNFLSNEASPLT VSVIDDKLKEKLVVEFQHIRNHSVEPLSQFLDYITYSYMIDNIVLLITGTLHQRAISELI PKCHPLGSFEQMEAIHIASTPAELYNAVLVDTPLAPYFIDCISEQDLDEMNIEIIRNTLY KAYLEDFYTFCESMGGGTAEVMCESLAFEADRRAFIITINSFGTELSKDDRAKLYPRCGR LYPDGLASLARADDFEQVKQVADYYAEYRVLFEESGNNPGDKTLEDKFFEHEVLLMKNAF MQQFHFGSFYAYVKLKEQECRNIIWIGECVAQRHRAKIDSYIPIFSPRKAIRKISKIPFK VLDAPELQDDFYLNLVDWSSQNVLSVGLGSCVYLWSACTSQVTRLCDLSCDGDSVTSVSW SERGNLVSVGTHKGHVQIWDVSSNKRVSVLEGHSARVGALAWNADVLSSGSRDRLILQRD IRTPSIVPERRLTGHRQEVCGLKWSPDHQHLASGGNDNKLFVWNMTSANPVQTYTEHLAA VKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCVDTGSQVCNLAWSKHSNELVST HGYSQNQILVWKYPSLVQIAKLTGHSFRVLYLAMSPDGESIVTGAGDETLRFWNVFSKTR STKESKSVLNMFTRIR------LYYLFTGQSYRFDIGWFLAGVPPYLWANLGIGLSISLS VVGAAWGIFTTGSSILGAGVKAPRIRTKNLVSIIFCEAVAIYGIIMAIVISNASNYFAGY AALGSGLTVGLSNLFCGICVGIVGSGAAIADAANSSLFVKILIIEIFGSAIGLFGVIVGI LQISHAHMGNK--------QELSDVVDESNILQWNGLIVPENPPYNKGAFRLKIDFPAEY PFKPPKITFLTKIYHPNIDEKGQVCLPIISAENWKPATKTDQVIQSLVALVNDPEPEHPL RADLAEEFSKDKKKFVKNAEEFTKKYGEKRPSDGASLTIPMQCSALRKNGFVVIKGKPCK IVEMSTSKTGKHGHAKVHMVGLDIFNGKKLEDICPSTHNMDVPKVSRKEYQIIDLTDGFF NLMADDGTMREDLKITATVWSSMGDEIVKELKIGKGKLLGPKGVCVDHNGHIIVVDNKAS SVFIFQANGKLLHRFGTRGEHQFAGPHFCAVNEANDIIISDFHNHCIKVFDEGTFKFSLG SNGEGNGQFNAPTGVAVDKIGNILVADWGNSRIQVFDSSGSFLSYINLYGPQGLSIAKDG NVVVADSGNHCFKIYRYL--------------------------AILWELFLQAGPVVNV HMPKDRITQMHQGYGFVEFMGEDDADYAIKIMNMIKLYGKPIRVNKASAHQKNLDVGANI FIGNLDPEVDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDTSDAAIEAM NGQYLCNRPISISYAFKKESKGERHGSAAER----------------------------- ------------------------------------------------------------ ----------------------------NPLFEKRPKNFGIGQDIQPKRDLSRFVRWPKY IRLQRQRAILFQRLKVPPPINQFTQALDRQTATQLFRLMDKYRPETRQEKKARLMGRAEE RVK--------------------------EKAQLVVIAHDVDPLEIVLFMPALCRKMGVP YCIVLGRVVRRKTATCLAFTQTNPEDRSSLNKIVEAVKTN-------------------- ---------------------------------NESPSDADLKKILSSVGIDADAECIKR VIGQLKGKNLEQLIEAGKEKLASVPSGGGAVAKEEKKEEGSDDDMGFGLFDMPISRIHAR QIFDSRGNPTVEVDLTTENGTFRAAVPSGASTGIYEALELRDKD-KSYHGKSVLKAVSNV NNCIAPALVLDLTNQAAIDQIMLDLDGTENKSKFGANAILGVSLAVCKAAAAKKGVPLYR HIADLAGNTEVILPVPCLNVINGGSHAGNKLAMQEFMIFPTGASSFHEAMRMGTEIYHHL KAVIKAKYGQDACNVGDEGGFAPNIQNNEEGLELLSQAIEKAGYTGKIQIGMDVAASEFC KKYDLDFKNPNSDPATWLNSDQLLEVYKGFVAKYPVVSIEDAFDQDDWDSWAKMNAIQLV GDDLLVTNPKRVRDAIEKKACNSLLLKVNQIGSVTESIEACKMSQDAGWGVMVSHRSGET EDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGANAKYAGVNFRNPGCPPS AGAYKKRPAGPTHFRKFYDRGDFPIALEHDTKGNKIAWKVEIEKLDYHHYLPLLFDGLCE TEHPYEFFARQGVHDMLEHGGGKILPVIPQLIIPIKNALSMRHPQVMCTTLKVLQHLVVS ADMVGEALVPYYRQILPVLNIFKNKNLNSGDGIDYSQQKRENIGDLIQESLEAFERHGGD DAFINIKYMVPTYESCM-------------DGEKKVTIEKDTKVPNAAIFTVNKEDHTLG NMLRTQLLKDPEVLFAGYKIPHPLESKFVLRVQTTSEYSPQEAFTNAITDLISEVSLLEE RF-----------EDHRRKWDREEYERLAQDRLDEELGKKEPPVKRDLLKPREYRVDLES KLNRSQVITKTTPSSQQGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRIERSSLD QVKARFEANKRKKEEEKKEYDFEERMKELKEEEEKQKAYRREKKKYKRKASDADDMDPDM AAVMGFTGFGGVKKMGCTMSAEERSALERSKQIEKNLKEDGIQAAKDIKLLLLGAGESGK STIVKQMKIIHEGGFTNEDNKQYKPVVYSNTIQSLVAIIRAMGTLHIDFGDPDREGDAKM VLDVIARMEDTEPFSEELLAAMKRLWTDSGVQECFGRSNEYQLNDSAKYFLDDLDRLGGR DYMPTEQDILRTRVKTTGIVEVHFHFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCV AMSEYDQVLHEDETTNRMQESLKLFDSICNNKWFTDTSEEKIKKSPLTICFQEYTGKQTY EEAAAYIQAQFEAKNKSTTKEIYCHQTCATDTNNIQFVFDAVTDVIIANNLRGCGLYYHS QFVNPPNVIGNMALLPLRTQFKGPAFDIIDEALYYFKANVFFKNYEIKGDADRTLIYITL YITECLKKLQRSPSRNQGQKEMHSLAISRFYLPGEAQFPLNAMYTKPSSRQEEDTMRAYF QQIRQETGLRVCEKVFDPQTDKPSKWWLCFTKRKFMDKSLSAPGQ---YNYSYIFKYIII GDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVAGQKIKLQIWDTAGQERFRAVT RSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIFLIGNKSDLEAQRDVTYE EAKQFADENGLMFLECSAKTGENVEEAFLDTARKIFQNIQDGSLDLNAAESGVQHKPSTP RNALSNDQQQQKEGCSCMSLVAVCVLRDSPVTGTVRFSQQNPVTVTGEVKGLAPGKHGFH VHEFGDNTNGCVSAGAHFNPSGKEHGAPEDENRHAGDLGNVVAGAVNITDNQLTLTGPNS IIGRTVVVHENEDDLGKGGHDLSKTTGNAGGRQACGVIGITKMVNFTIDEIRNIMDKKKN IRNMSVIAHVDHGKSTLTDSLVSKAGIIAGSKAGEARFTDTRKDEQDRCITIKSTAISLY YTLPEKDLECSFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQA IAERIKPVLFMNKMDLALLTLQLGTEDLYQNFCRIVENVNVIVCTYGDESNPMGDIQVDP AKGTVGFGSGLHGWAFTLKQFSELYSGKFKIEETKLMKRLWGDQFYNYVRGFTQYILDPI YRVFNFCMTKEEALALVEKLGIKLTAEDKELHEKQLLKTVMRKWLPAGDALLQMITIHLP SPVTAQRYRVDMLYEGPLDDESATAVRNCDDKGPLMMYISKMVPTSDRGRFYAFGRVFSG CVSTGQKARIMGPNYVPLKTIQRTILMMGRYVEPIEDVPCGNICGLVGVDQYIMKTGTIS TLDSSHGMKTMKFSVSPVVRVAVECKNPADLPKLVEGLKRLGKSDPLVQCTIEESGEHIV AGAGELHLEICLKDLEEDHACIPIKVSEPVVSYRETVSEDSDRMCLSKSPNKHNRLFMKC RPMPDGLAEDIDD--VSPRQELKERARYLAEKYDYDVTEARKIWCFGPEGTGPNVVMDCS KGVQYLNEIKDSVVAGFQWASKEGVLCEENMRGVRFDIHDVTLHADAIHRGGGQIIPTTR RVLYACVLCAAPRLLEPVYLCEIQCPEAAIGGIYGVLNRRRGIVFEEHQTPGTPMFVIKA YLPVNESF--------------------------VVAGIRKRKGLPEGIPPLDRFLDKLM LPLSLLRTAVNHPMLVELKNGETYNGHLVSCDNWMNINLREVICTSRDGDRFWRMPECYI RGSTIKYLRIPDEVIDMVKEEVLQKSKGRGDSR------PG------------------- ---NEFKLNSPPTDGVSAVKFCPGSSQFLLSSSWDCSVRLYDVSSNLMRMKYNHQAPVLD CCFQDTVHAYSGGVDSAVKMYDFNSNSENTVGKHDGPVRCIEFCPEVNVIISGSWDSSVK LWDPRTPCCAGSFAQPERVYTMSVCGDKLIVGTAGRRVLVWDLRNMGYVQQRRESSLKYQ TRCIRSFPNKQGYVLSSIEGRVAVEYLDPSPEVQKKKYAFKCHRIKEGDVEKIYPVNAIS MHSMYNTFATGGSDGFVNIWDGFNKKRLCQFHRYPTSISSLSFSHDGSMLAIALSYMYEN EQPEDAIFIRRVSDQETKPKMDFQHRAGGKTGSGGVASSSETNRDRRERLRQLALETIDL NKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQANLARRAAKEAKEAPAQPAPE KARVDIKKFVKIGRPGYKVTKQRDPESMQQSLLFQIDYPEIVEGITPRHRFMAAYEQRIE PPDKKWQYLLFAAEPYETIAFKVPSREVDKDGKRFWTHWNRETKQFFLQFAFKVDAKHSN MPPPGIHQSNIHMDDELETIKFWRIRKTVMQLCHDRGYLVTQDELDQTLEQFKEQFGDKP SERKPARSDLIVLVAHNDDPTDQMFVFFPDEPKVGIKTIKTYCQRMQEENISRALIVVQA GMTPSAKQSLVDMAPKYILEQFLEAELLVNITEHLLVPEHVLMTTEEKQELLIRYKLKES QLPRIQAGDPVARYFGLKRGQVVKIIRPSETAGRYISYRLVV-KNGRVGTVIGIDLGTTY SCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDVKRLI GRRWDEPSVQQDVKFFPFKVINKNSKPYVEISTGTENKVFAPEEISAMVLIKMKEVAEAY LGKKVTHAVITVPAYFNDAQRQSTKDAGAIAGLNVMRIINEPTAAAIAYGLDKREGEKNI LVFDLGGGTFDVTLLTIDNGVFEVLSTNGDTHLGGEDFDQRVMDYFIKLYKKKKGVDVRK SNRAVQKLRREVEKAKRVLSSQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMK PVQKVLEDADLQKNEVQEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEAVAFGAAV QGGVLSGEEDTGDLVLLDVNPLTLGIETVGGVMTKIISRNTVIPTKKSQIFSTAADNQPT VTIQVYEGERPMTKDNHILGKFDLTGVPPAPRGVPQIEVTFEIDVNGILRVSAEDKGTGN KNNIVINNDQNRLSPEDIERMINDAEKFADDDAKLKERVESRNELESYAYSLKNQI---- ------------------------------------------------------------ ----------DESVDDPELEAIKARVREMEEEAEKLKEMQSDLDLSMSIEEKIDVDTRSV WVGNVDYGATAEELEAHFHGCGSINRVTILCDKFTGHPKGFAYLEFADKDSIHTATALDD SLFRGRQIKVCAKRTNRPGISSTNRPPRGGGGRPRG--GTYGYAPRPRGRG-FRPRRVNY YSPYVLFGTLLELSNSGGFQTLIAAVKNEKEKKAKLQQTIQQEEQGRKRVRLLQRRLLEV KKEKEVEVQQRNEMIAHLKDQLQEMKAKTNMEGKYIKKCAEVSVAQTQKRCNNGEKGCRD EIESLKEKIDEENRVNAEIESFLRTHTERLQKMVDHWMEKYDKDVESKQKELDILKASKA KDLERLQELTKLYSEYEQVVVEDRIEKEKARRKAEQE----------------------- -----------------FGRIGRLVLRCALQQVNVVAVNDPFIELDYMVYMFKYDSTHGR YKGDVSLVVDGVAITVHQCMKPSDIPWGADGADYVVESTGVFTTIEKANAHIQGGAKKVI ISAPSADAPMFVMGVNECGYDKSMNIISNASCTTNCLAPVAKVVNDNFGIVEALMTTVHA ITATQKTVDGPSAKAWRDGRTAAGNIIPASTGAAKAVGKVIPALNGKLTGMAFRVPVSDV SVVDLTCRLEKGATMDEIKAAMKGPMKGFLGYTEDQVVSSDFISDTHSSFFDARAGIALN SNFVKLISWYDNEFGYSNRVVDLI------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------DIGGCRKQLAQIK EMVELPLRHPQLFKAIGVKPPRGIMLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSK LAGESESNLRKAFEEAEKNSPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQ RSHVIVMAATNRPNSVDTALRRFGRFDREVDIGIPDATGRLEILRIHTKNMKLADDVDLE QVASETHGHVGADLAALCSEAALQQIREKMDLIDLEDDQIDAEVLDSLAVTQEDFRWALG KSNPSALRETAVEVPNVSWEDIGGLENVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFY GPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFD ELDSIAKARGGNAGDGGGAADRVINQLLTEMDGMSSKKNVFIIGATNRPDIIDPAILRPG RLDQLIYIPLPDDKSRIQILKANLRKSPVAKDVDLDFLATTANGFSGADLTEICQRACKL AIRENIEAEIRKERERAENP--------IRRDHFEEAMKFARRSVTDNDIRKYEMFAQTL QQSRGFGGGDTSAFGATSVFGNSTNYNPMKDMEVTSPPDDSVSSMAFSPGVLPTTFLVAG SWDNNVRCWEVQQNGQTIPKAQQTHTGPVLDVCWSDDGTKVFTASCDKTAKVWDLNSNQA IQVAQHDAPVRSCKWVKAPSYSCLMTCSWDKTVKFWDTRTPNPMMTIQLPERAYCADVLY PMAVVGTAGRGVIIYQLENQPQEFKRTESPLKYQHRCVSIFVDKKSNAPTGFALGSIEGR VAIHYVNPQNPKDNFTFKCHRGGVQDIYAVNDIAFHPVHGTLATVGSDGRFSFWDKDART KLKTSEQLDQPISCCTFNAQGNIFAYSSSYDWSKGHEGFDPQKMKPHIFLKSCYDELKPS QKKMSSPSPGKRRMDTDVVKLIESKHEVTILGGLNEFIVKFYGPQGTPYEGGVWKVRVDL PEKYPFKSPSIGFMNRIYHPNIDEVSGTVCLDVINQAWTALYDLSNIFESFLPQLLTYPN PIDPLNGDAAALYLHKPDEYKKKVTEYVKKYATEEALREQESSMSDFSEDETQDMELMDE SEILTTLKILIIGESGVGKSSLLLRFTDDTFDPEQSATIGVDFKVKTLTVDGNRAKLAIW DTAGQERFRTLTPSYYRGAQGCILVYDVSSRNTFTRLENWLNELETFSTKHEIVKMLVGN KIDKDKREVTRDEGLKFARKHHMLFIEASAKTKEGVQCAFEELVEKIIQTPGLWETDGLS VGRVIWSIINGTFCSFKTQTKTQKFCRNEFNLTGLCNRSSCPLANSQYATVREEKGVCYL YMKTIERAAFPARLWEKVKLSRSYEKALKQIDEHLIYWPRFLKHKCKQRFTKITQYLIRM RKLVLKRQKKLVPLSRKIERRDSRRQEKALIAAQLENAIEKELLERLKSGTYGDIYNFPQ VAFDKALEAEELDEESEEEGEIEYVAEEEFEESD-------------------------- ------------------------------------------------------------ ------------------------MYVIKDLVPDMNNFYAQYKYIEPYLKKKDLKEEDIG KTAYFQSPEDRAKLDGMYECILCACCSTSCPSYWWNGDKYLGPAVIMQAYRWIMDSRDDF KKERMEQLRDKWSLYRCHTIMNCTKTCPKGLNPGAAIGELKKIMIGYESKGIPRQ----- ------------------------------------------------------------ ---------------------------------------------------APTAMPEQP PHHILFLTNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENEVQAGAAKDALQ GFKITPTNAMKISFAKKMDSQGRKVVVCDNGTGFVKCGYAGSNFPAHIFPSLLGRPILRS NTKVDDIEIKDLMIGDEASKLRSMLEVTYPMENGIVRSWEDMIHLYDYTFGSQKLNINPR ECKLLLTEPPMNPTKNREKMIEVMFEHYGFHGLYIAIQAVLTLYAQGLLTGVVVDSGDGV THICPVYEGFALPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRQMKEQLCYV GYDIEQEQKLAIETTVLVESYTLPDGRVIKVGGERFEAPEALFQPHLINIEGLGVAELLF NTIQQADIDTRPEFYKHIVLSGGSTMYPGLPSRLEREIKQLYLERVLKGNTESLAKFKIR IEDPPRRKHMVFLGGAVLGDIMKDKESFWLSRSEYQERGL---------MSETQGKTITC QAAVAWEAKKPLSIETIEVAPPKAGEVRIKILATGVCHTDAYTLDGFDPEGLFPVVLGHE GGGVVESVGEGVTSVAVGDHVVPLYIPQCGECKFCKSPKTNLCSKIRTTQGAGMMPDGTS RFTCNGKQLFHFMGTSTFSEYTVAAEISVAKVNPKAPLDKVCLLGCGISTGYGAALNTAK VEEGSNCAVWGLGAVGLAVLMGCKEAGASRIIGVDINPDKFEIAKQFGATECINPKDFDK PVQQVLTEMTDGGLDYTFECIGNVATMRAALESCHKGWGVSTIIGVAAAGQEISTRPFQL VTGRVWKGTAFGGWKSRESVPRLVDEYMTGKVKVDEFVTHTLPLDKINEAFDLMHAGKSM ETYDVIANQPVVIDNGSGVVKAGFAGDQIPKYHFPNYIGRPKHVRVMAGALEGDTFIGPK AEDHRGLLTIRYPMEHGIVTDWNDMERIWQYIYSKDQLQTFSEEHPVLLTEAPLNPRTNR EKAAEIFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHSVPIYEGFAMPHSIM RTDIAGRDVTRYLQLLLRKEGHNLHTTAEFEIVRSIKERACYLSINPQKEETLETDRATY TLPDGAVVEIGPARFRAPELLFRPDLIGEEYEGIHEVLAYAIQKSDMDLRRTLFSNIVLS GGSTLFKGFGDRLLSEVKRLAPKDIKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKR EYDEEGARAINRKTF---KVDKVDVHPLVLLSVVDHFNRMGRVGNVKRVVGVLLGSNRQG VLDVSNSFAVPFDEDDKDKSVWFMDHDYLEHMAGMFKKVNAREKVVGWYHTGPKLHENDV AINELVRKYCPSSVLVIIDAKPKDLGLPTEAYIAVDEVHDDGTPTTKTFEHLPSEIGAEE AEEVGVEHLLRDIKDTTVGTLSQRVTNQLMGLKGLFSQLRDVHSYLEKVVSAKLPINHQI IYQLQDVFNLLPDVNLQELVKAVYIKTNDQMLVVYLASLIRSIIALHNLINNKIQNSDAE KNEGKSEKMGLLFSKLWGLFTNEEHKVIIVGLDNAGKTTILYQFLMNEVVHTSPTIGSNV EEVIWKNIHFIMWDIGGQESLRAAWNTYYANTEFVILVIDSTDRERLSITKEELYKMLSI EDLKKAAVLIFANKQDLKGAMSAAEISRQLNLTSIKDHGWHIQACCALTGEGLFQGLEWI TNHLRR--IPIRRVLLNDPSQLPSDYSQTPGGTLFSTTPGGTRIIYDRNFLMQCRNSPLA KSPPANLPKIPGVTSPPPPGKRKEIYKYEAPWTVYSMNWSVRPDKRFRLALGSFVEEYNN KVQIVSLDEESSDFVARSTFEHPYPTTKIMWIPDSKGLYPDLLATSGDYLRVWRVTRLEC LLNNNKNSDFCAPLTSFDWNEVDPNLLGTSSIDTTCTIWGLETGQVLGLVSGHVKTQLIA HDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLAWNKQ DPNYLATMAMDSMEVIILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQAL IWDIQQMPRAIEDPILAYTASGEINQIQWSLAHPDWISICYNNCMEILGV---------- ----AGGIGQPLSLLLKLNPRITTLALYDIVNTPGVAADLSHCSTPAQVTGFIGPDQVRD CVEGSDVVVIPAGVPRKPGMTRDDLFNTNASIVRDLSQACAEACPKAIICIISNPVNSTV PIASEVYKNVGTYDPNRIFGVTTLDIVRSNTFIAQLKGLEVSQVNCPVVGGHSGVTIVPL FSQCTPPVSFPSEERDKLTHRIQNAGTEVVEAKAGTGSATLSMAYAGARFADSILQALAG EEGIVECAFVRSDETEAKYFSTPILLGKNGLEKNLGLGKLLEYEVNLIKTAMPELQKNIQ KGEDFVNKNIDKGKDFNIKTRIITDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFAS TLSHLRRVNSPIGRDGKLARPRQLHNSQWGMVCPAETPEGAAVGLVKNLSLMAYISVGSQ PSPILEFLEEWSMENLEEIAPSAIADATKIFVNGCWVGIHRDPEQLMNTLKKLRRQMDII VSEVSMVRDIRDREIRIYTDSGRICRPLLIVENQKLLLKKRHIELLKEREYNNYSWQDLV ASGVVEYIDTMEEECIMLAMTPDDLQEKGVAYCSTYTHCEIHPSMILGVCASIIPFPDHN QSPRNTYQSAMGKQAMGVYITNFHVRMDTLANVLLYPQKPLVTTRSMEYLRFRELPAGIN AIVAIASYTGYNQEDSVILNESAIDRGLFRSAFFRSYKDSESKKGLDQEEIFEKPDRQST QGMRNAVYDKLDDDGIIAPGTRVSGDDVLVGKTMTLPENDDELEGQARRFTKRDCSVFMR RSETGIVDQVMVTINNEGYKFVKIRVRTVKTPQIGDKFASRHGQKGTCGIRYRQEDMPFT CEGITPDVIINPHAIPSRMTVGHLIECLQGKVSSNKGEIGDATPFNDTVNVQKISNLLHE YGYHLRGNEVLYNGYTGRKLNAQVFLGPTYYQRLKHMVDDKIHSRARGPVQILNRQPMEG RSRDGGLRFGEMERDCQIAHGAAQFLKERLFEISDPYRVHVCNICGLIAIANLRNNTFEC KGCKNKTQISQVKLPYACKLLFQELMSMSISPRMMVLCVETQGGFSFENCTRNAAISKGF KAPTAYKTGTTICGIVYKDGVVLGADTRATEDTIVADKNCAKIHYIADNIYCCGAGTAAD TEMTTNMISSQLELHKLNTGRVPRVCTANRMLKQMLFRYQGHISAALVLGGVDCTGPHLY SVYPHGSTDSLPYVTMGSGSLAAMAVFEDGYQPDMEKEEAMKLVRNAIAAGIFNDLGSGS NVDLCIITKKVEYLRPYDQANVKGVRQGQYNYKKGTTAVLTEKVKMLNFDVV-SKVTFKI TLTSDPKLPYKVLSVPEQTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPAQSAGNVFL KHGSELRLIPRDRVG----------FITALILSAFLIFFVIYHIIAFDELKTDYKNPIDQ CNSLNPLVLPEYILHGLYNVLFLLSGCWGTFLLNVPLIGYHIKRYTQRPVMSGAGLYDPT TIMNADELSRAQKEGWIKLAFYLLSFFYYLYSMIYELVSS-------------------- --GLDNAGKTTILKKFNGEDIDMISPTLGFNIKTLEHRGYKLNVWDVGGQKSLRSYWRNY FESTDGLIWVVDSADRRRIQDCRQELDALLLEERLAGATLLVFANKQDLPGALPSEEIKQ VLELDNIKSHHWLIQGCSAVTGENLLTGIDWIIDDIASRIFTMDHSKRKVCYYYDGDIGN YYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPQKASYEEMTKFHSDEYIRFLRSIRP DNMSEYNKQMQRFNVGEDCPVFDGLYEFCQLSTGGSVAGAVKLNKQATDMAVNWGGGLHH AKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY GEYFPGTGDLRDIGAGRGKYYAVNFPLRDGIDDESYEQIFQPVMAKVMEMYQPSAIVLQC GADSLSGDRLGCFNLSLKGHGKCVEFMKKYNLPLLMLGGGGYTIRNVARCWTYETSVALG VDVANELPYNDYFEYYGPDFKLHISPSNMANQNTPEYLDKIKTRLFENLRMLPHAPGVQM QDIPEDAIKDEQDPDRRISIRASDKRINCEEEFSDSEDEGESGRKHKENYNKRKRQNAAF ECNICLDTARDAVVSMCGHLFCWPCLHQWLETRPNRQVCPVCKAGISKDKVIPLYGRGST DQQDPREKVPPRPAGQRPEPENNANFPGFGFGFQMSFGIGAFPFGFFASTFNLNDGRPAP PTPGTPQHGEEQFLSKIFLWVAVLFIFWLLIAMYALMHKSEQAHDDSIWSCAWAKSEKDG VENILTGSVDDTVKVWKWMDLELRHTLEGHQLGVVSVDINPSGTMAASSSLDSHVRLWDL EAGKQIKAIDAGPVDAWSIAFSPDSRFLASGSHTGKINLFGVESGKKESQLDTRGKFTLS IAYSPDGKFIACGAIDGIINIFDMTTGKHLEGHAMPIRGLCFSPDSKLLITASDDSHIKI YDVQHANLAGTLSGHGSWVLSVNFSPDNIHFVSSSSDKTVKVWDSGTRQCVHTFYDHTDQ AWCAKYNSSGTKIVSVSEDRAIHVYDVPVETPQQFDDRYEAFFDRKDIDGWEIRKAMNDL QGYDLVPEPKIVSAALRACRRVNDHSLAVRYLEAVKDKCGNKKDEIWPYMMQQIKPTMDE LGVSSLEELGYDKPELALEDVFDMVVRVRGLPWSASHEEVAEFFQGCNMSEGKAGIHFTY VRDGRPSGEAYIELETEDDLAKALSKDKHHMGKRYIEVFRSKRSEMDWVVKRGGPNQDAV VRLRGLPFGCSKEEIAHFFSGMEIVPNGISLLQDHQGRTTGDAYVQFASQEIAEKAQQKH KERIGHRYIEIFKSSLQELRN----------HMRGLPFAASEQDILDFFKPLNPVNVVIH FNNGRASGEADVDFATHEEASEAMKKDRASMQHRYIELFYQDKDKPTQIRFSNITAAKAV ADAIRTSLGPRGMDKMIQAGGGDVTITNDGATILKQMQVLHPAAKMLVELSKAQDIEAGD GTTTVVVIAGSLLDAAQKLLIKGIHPTIISESFQRAAAKSVELLESMAIPLELSDRESLL KSATTSLNSKVVSQYSSLLSPLCVDAVMKVVDPAKDTNVDLRDIKVIKKLGGTIEDTELI DGLVFSQKTAGYGGPNKVEKAKIGLIQFCISPPKTDMENNVIVSDYTQMDRVLREERQYI LNIVKQIKKAGCNVLLIQKSILRDAINDLALHFLAKMKIMVIKEIDREEIEFVCRTLGCR PVASLDHFLPEVLGSADLVEEVQTGDSKVVKITGIQNAGKTVSVIVRGSNKLVLEEAERS IHDALCVIRCLVKKRALIAGGGAPEIELALRLAEYSQTLTGMEQYCFRAFADALEIIPFT LAENAGLNPIATVTELRNRHAENEKTAGINVRKGAITNILEENVLQPLLVSVSAITLAAE TVRSILKIDDIVNCQMILLEIHNRIIRDTLVQKFKNVQSGNKPDLVDITIADFDGVLYHV SNPGGDKTKIQVSISLKFYKDLQEHGADSLLQREYGQYLTTPEQGYDASLLYDENIPQNS EKVAEHASLLKRNCFASVFEKYFDFQERHKRAIIQYRDDETMYVAAQKDRVTVIFSTVFK DDDDIVIGKVFMQEFKEGRRRYQQGPQVLFSHKDPPMELKGTDARTGDNIGYITFVLFPR HENRDNTIDLIHTLRDYLHYHIKCSKAYIHSRMRAKT----------------------M LMFCPTCANVLVAEEGPKCYRFACNTCPYVHNITKKISSRKYPKLKEVDDVLGGAAAWEN VDSTEETCPKCSHDKAYFMQIQTRSADEPMTTFYKCCNPDCAHRWRKTKFGDLKDQDRVF TNLYGRHDWTLKGAMARGDWYKTKEIILKGHEWIQGEIKGSGLRGRGGAGFPTGMKWSFM NKPDDGRPKYLVVNADEGEPGTCKDREIMRHDPHKLIEGCLVAGSAMGACAAYIYIRGEF YNEASNVQVAINEAYKAGFLGKNACGTGYDYDIYLHRGAGAYICGEETSLIESLEGKAGK PRLKPPFPADVGVFGCPTTVNNVETIAVAPTICRRGGDWFATFGRPRNTTVMMDFDDLVA NQTALGTAALIVMDKSSDVIRCIARLMEFYKHESCGQCTPCREGVSWMNTILQRFVSGNG QPGEIDLLQEMSKQIEGHTICALGDGAAWPAQGLIRHFRPVIEQRMKQFS---FTQEQVD DMNQQLSQTRSQRVRAAMFPETLEENLQIPSTQIHPDQPTAVQRLAEPSQMLKHAVVNLI NYQDDADLATRAIPELTKLLNDEDQVVVSQACMMVHQLSKKEASRHAIMNSPQMVAALVR AMSNTNDMETTRCAAGTLHNLSHHRQGLLAIFKSGGIPALVKLLSSPMESVLFYAITTLH NLLLHQEGSKMAVRLAGGLQKMVALLQRNNVKFLAITTDCLQILAYGNQESKLIILASGG PGELVRIMRSYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQGLAMHLGHQSTRLVQN CLWTLRNLSDAATKTDNMEGLLQMLVQLLTSNDINIVTCAAGVLSNLTCNNQRNKVTVCQ VGGIEGLVRAILQAGDREDITEPAVCALRHLTSRHPEAEMAQNAVRLHYGLPVLVKLLHP PSRWPLIKAVVGLIRNLALCSANHAPLREHGAIPRIVQLLMRAHQDTQRGSGAFVDGVRM EEIVEGTVGALHILAREPHNRAVIRGLSCIPLFVQLLYSPIENIQRVAAGVLCELAADKE GAEIIEQEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRGE QMSADLQWMIIRNNSSFLLKGKTFSREANNLKNRNSFRYNGLIHRKSVGVEPASDGKGVV LVTKRNQRKPGKSFTRVELKRGSRR--------LKNNRYRRDMKMPALRRASAILKSQKT VVVKKTRDVPYYCSEQINIPPELPDILKQFTKSAIRTQPKDVLAWSAAYFRAMANGETPP VKERLEMPVATQKTDTGLTAGLLRVINKQLGPKKNVALSLVEEKWKDLALPKEQFDELVQ IGSFGGDIEWLKFFALACSTLGENVSDAMKTVCEILTADPDGGPARIPFQLFQDLYKYLA QVDGEISHEHINTVINYLMYHVDKQDGFVQPRNFLSPDCPNLS---DAGQREQLMEQVKA QIAVANAQELLQKMSDKCFQKCVTRPGTSLDSGEQKCVAMCMDRYMDAWNIVSKVYTQRL QRERGR-MNRLFGRSKPKGPAPNLNDCITNIDSRGESIDKKIGRLEQELGKYREQMKKMR DGPSKNMVKQKAMRVLKQKRMYENQREGLMQQSFNLEQSNYAIQTVKDTKTTVDAMKLGV KEFKKEYKGMNIDNIEDIQDEMEDLTEQAGEIQEIMGRSYGMPEIDDDELEAELDALGDD LAFDEDTSYLDEASKAPGVPSAMPGADSMTNKDGVPVDEFGLPQIPAQMTPLNPQTPASP QLQNIVCTVNLTCKLDLKKIALHARNAEYNPKRFAAVIMRIRDPRTTALIFSSGKMVCTG AKSEDQAKLAARKYARIVQKLGFPAKFMDFKIQNMVGSCDVKFPIRLEGLVLTHAQFSSY EPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKVRKEIYEAFENIYPILKGFRKQMQEDD DDFVDI-VDSEAGTQDDEEHFAFQVLTTDKIVQHMVDCIKDVNHVVQIPATITRILLNHF KWDREKLMECYYDGDQDKLFSEAHVISPFKKTMEAVCDICYLSFPNMFNGLECGHKFCSQ CWGEYLTTKIMDEGMGQTISCAAHGCDILVDDQTVMDLVTEPKVRLKYQHLITNSFVECN RLLRWCPTPDCGHAVKVQYYDKKPVTCACGHTFCFACGENWHDPVKCKWLRKWIKKCDDD SETSNWIAANTRECPKCHATIEKDGGCNHMVCKRCKFDFCWVCLGPWEPHGSSWYNCNRY DEDEAKKARDAQGKSRAALQRYLFYCNRY------------LYASIKLKMEEMQQHNMSW IEVQFLKKAVDILCQCRQTLMYTYVFAFYLKKNNQSIIFEENQKDLENATEQLSEYLERE ITSEMLADIKQKVQDKYRYCESRRKVLLDHVHEGYEKELWEYYDMATTDGKMSTTERVVK SVPFPPSHRLTMSEVFDSKGKPRPDVFKQHFILEGRVTEDVALRIINEGAALLRQEKTMI DIEAPVTVCGDIHGQFYDLMKLFEVGGSPATTRYLFLGDYVDRGYFSITERVYDACMEAF DCLPLAALMNQQFLCVHGGLSPEIHNLDDIRKLDRFKEPPAFGPMCDLLWSDPLEDFGNE KTTEHFTHNSVRGCSYFYSYAACCDFLQQNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSL ITIFSAPNYLDVYNNKAAILKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVT EMLVNVLNICSDDELMSEGDDTFE--VAARKEIIRNKIRAIGKMARVFQVLREESESVLQ LKGLTPNGLLPIGALSGGKDSLRSAMSGFSPTHKISGFVEAKYLDKLNERMPPRK----- -------------------------GRGGRGGMRGGKKVVIEPHRHEGVFIARGKEDALV TKNMVPGESVYGEKRITSEDNNKVEYRAWNPFRSKLAAAILGGVDDIHMKPGSKVLYLGA ASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINVAKKRTNIIPIIEDARHPHKYRMLVG MVDTIFADVAQPDQARIVAINAHHFLKSSGFIVISIKANCIDSTAEAEAVFAGEVNKLRS EKIKPKEQITLEPYERDHAVVVGHYRPPPKK-----------RLKKAGRGGGIGLGFLAA AGGAAYGLYQSMYTVDGGHRAIIFSRIGGVQDDIYSEGLHFRIPWFHYPIIYDIRARPKK ISSPTGSKDLQMVNISLRVLSRPEARKIPEIYRTLGTDYDERVLPSICNEVLKSVVAKFN ASQLITQRQQVSLLIRKELTERARDFNIVMDDVAITELAFGREYTAAVESKQVAQQEAQR AQFIVERAKQERQQKVVQAEGEAQAAILIGESVALNPGYLRLRKIRAAQSIARTVAQSKN RVYLNAGTLM-------------SYTGSSSDEEEVNPRERXQKNSSGFTDFCIRIEQAAF GRREIEIAEQEMPGLVALRKRAQGDKPLSGAKIVGCTHITAQTAVLLETLRALGAQVRWS ACNIYSTQNEVASALAEAGVPVFAWKGESEDDFWWCIDKCMSSDNWQPNMILDDGGDATH LMLKKYPSQFSMVKGIVEESVTGVHRLYQLSKSNKLSVPAMNVNDSVTKTKFDNLYSCRE SILDALKRTTDVMFGGKQVVVCGYGEVGKGCAAALKGMGAIVMVTEIDPICALQACMDGM RVCKLNEVVRNVDLVITCTGNKNVVIREHMDKMKNGCIVCNMGHSNTEIDVNSLRTPDLT WERVRSQVDHIIWPDSKRIILLAEGRLVNLSCSSIPSFVVSITAATQALALIELFNAPPG RYKQDVYLLPKKMDEYVASLHLPNFDAHLTELNDDQAKYLGLNKAGPFKPNYYRYPDPDA IKMFVGQIPRSMDENDLRKMFEEFGPVFQLNVLRDKVTGQSKGCCFVTFYTRKSALDAQN DLHNIKTMAGMQHPIQMKPADSEKRS-EERKLFIGMLAKKCTENDVRMMFAPFGTIEECT VLREQNGQSKGCAFVTYASKQCAMNAIKSLHQSQTMEGCRSPLVVKFADTQKEKEMKKLQ QMQ------FSGGTAGGVASVYVGQPLDTVKVKMQTFPTLYRNAWHCFVSTLRTEGQRGL YAGTIPSLENAILFMAYGMCQKAVACAAFFSSLSLCPTELVKCKLQALTKQILREEGIAG LFRGLVPTLAREMPGYFFFFGGYEICRELLTPPGKSKDNLSPKTIFCGGMGGVALWIAVF PADVIKSRVQVRREGILALYKGLGPTLARTFPATGALFFCYEKTKSVVA---HDFNRLAT VVANNVAKIAKNYNDMQRMISQIGTPQDNSDLREKLHNIQHYTNRVAQETNGYMKQLHSC QSEQRQKKIQKDRLVNDFSTALKNFQSAQRSAAEKEKESVQDVDLSLIQEREQAIQKLES DIVDVNQIFKDLGMLVHEQGEVVDSIEANVESIQVEQGTTQLAKAREYQTKARRKKCIII LIVVLILAIIATIIGVSV-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXGKKGEKAPSPQEAIQRLRETEEMLQKKSDFLEK KVEQELSTARKRAALQALKRKKRYEKQLQQIDGTLSTIEFQREALENASTNTEVLKVMGD AAKALKGAHKNMDIDDVHNLMDDVAEQQEIANEISEAISNPVGFGQDVDDDDLMAELEEL EQEELDEKLLDVENLPSVPVAEDDEMAELAAWATSMQRFHNRVRQILMASGSTTFTKIVN KWNTALIGLMTYFREAVVNTQELLDLLVKCENKIQTRIKIGLNSKMPSRFPPVVFYTPKE LGGLGMLSMGHVLIPQSDLRWSKQTDAGITHFRSGMSHDEDQLIPNLYRYIMPWESEFID SQRVWAEYALRTDMIQALGGVEGILEHTLFKGTYFPTWEGLFWEKASGFEESMKYKKLTN ASKDTMDNSTTQKYWLDIQLRWGDYDSHDIERYARAKFLDYTTDNMSIYPSPTGVLVALD LAYNLHSAFGNWFPGCKPLIQQAMAKIMKANPALYVLRERIRKALQLYSSEPTEPYLSSQ NYGELFSNQIIWFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSV WAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKG SELQLPFQACLKVEKFGDLILKATEPQMVLFNLYDDWLKTISSYTAFSRLILILRALHVN NDRTKIVLKPDKTTVTEQHHIWPTLSDDEWIKVEVQLKDLILADYGKKNNVNTASLTQSE IRDIILGMEISAPSAQRQQIAEIEKQTKEQSQLTATTTRTVNKHGDEIITSTTSNYETNT FASKTEWRVRAISATNLHLRTNHIYVSSDDIKETGYTYILPKNILKKCIIISDLRAQIAG YLYGVSPPDNPQVKEIRCIVMPPQWGTHQTVHLPNHLPDHEYLKEMEPLGWIHTQPNELP QLSPQDITTHSKVMSDNPSWDGEKTIIVTCSFTPGSCSLTAYKLTPSGFEWGRQNKDTGN NPKGYLPSHYEKVQMLLSDRFLGFFMTPGQTSWNYNFMGVRHEPNMKYDLALSNPKEFYH EVHRTSHFLNFSSLEEGTDREDLY--------NLLINKSTKVICQGFTGKQGTTHSQQAI EYGTNMVGGVSPGKGGKTHLGLPVFNTVSEAKVGTGAEASVIYVPPSFAAKAILEAIEAE IGLVVVITEGIPQQDMVRVKQALLSQSKTRVIGPNCPGIIKPGECKIGIMPGHIHKPGNI GIVSRSGTLTYEAVHQTTVAGLGQTLCVGIGGDPFNGTNFVDCLECFLQDPATEGIVLIG EIGGGAEERAAEYLQEHNGPNAKPVAAFIAGLTAPAGRRMGHAGAIIAGGKGGAQEKIQI LKNAGVEVTLSLAQMGTTIRKAME---------LRCTLCNERLEDTHFVQCPSVPEHKFC FPCSRESIKRQGAGTEVYCPSQKKCPLVGSTVPWAFMQNEIATILGYSRFVELGRVAYVA YGPDEGKLVAIVDVLDQSRALVDGPCTGVVRRVASFKQLHLTPYCIIARSARVGTVIKAW NKAEIDQKWAESAWSKKIAAREVRKTLTDFDRFKLMKAKQSRNRLVNIEYGKVRSAAKQT CPLLLRVFCSTGRHHPLNEYARGNTPANELQIYTWPDASLKELTSLVKEVNGDARKKGTF FDFAVVFPDSRSPTYRMREIGSTCAGRKGTDDAMTLGIKRFQTGDYLDIAITPPRGLGKT LQTISLLGYMKHYRGLPSPHLIIVPKSTLANWMNEIARWCPSLRAVCLIGDQEKRSALIR DVILPGEWDICVTSYEMCIKEKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKSANR LLLTGTPLQNNLHELWALLNFLLPDVFNNSEDFDAWFNASSCMENNELVERLHAVLRPFL LRRIKSEVEKKLLPKKETKIYIGLSKMQREWYTRILMKDIDVVNGAGKSDKMRLLNILMQ LRKCCNHPYLFDGAEPGPPYTTEKHLVDNCGKMVLLDKLLPRVKEQGSRVLVFSQMTRMM DILEDYCIWRNFEYCRLDGQTPHEERQTSINEFNAPDSSKFIFVLSTRAGGLGINLATAD VVIIFDSDWNPQVDLQAMDRAHRIGQMKQVRVFRFLTENTVEERIVERAEMKLRLDNVVI QQGRLVDEKTNKEVLQMIRHGANHVFAAKDSAITEEDIDSILERGQQKTEEMNAKLADLG ESSLKSFSLDTQD-SVYKFEGEDYRDRQKIPGIGHWIEPPKRERKANYAVDAYFREALRV SEPKAPKAPRPPKQPNVQDYQFFPPRLFELLDQEIYFYRKTIGYRVPKDPDLGADAERIR KEEQKKVDEADTLSEEELKEKEDLLRGFSIWSKRDFNQFIKANEKFGRDDIENISKEVEG KTPEEVIEYSTVFWERCSELQDIERIMAQIERGEAKIQRRISIKKALDAKMSRYRAPFHQ LRIQYGTNKGKNYTEEEDRFLVCMLHKLGFDRENVYDELRTAVRQAPQFRFDWFIKSRTA MELQRRCNTLITLIERENMELEEREKAERKR--KPSWAEQVEQGEDDALPPPHEDFDEKT GMKTIIEYKYNDEGKKVRVVKTFKIETKRVSKSIATRKSWKKFGAASNDPPGPNPANTIE DCFVQFVNAKEIEDGDPLNKLKVSCRICKGDHWTTRCPYKDTLAPIQDALTQLGKYVPPS MRDGGNKRGESMSADEAATIRVTNLSEDTRESDLQELFRPFGSISRIYLAKDKITGQSKG FAFINFHRREDAARAIAGVSGFGYDHLILNVEWAKPSMSETYDFLFKFLVIGSAGTGKSC ILHQFIENKFKQDSNHTIGVEFGSKVVNVGGKSVKLQIWDTAGQERFRSVTRSYYRGAAG ALLVYDITSRETYNALTNWLTDARTLASPNIVIILVGNKKDLEAEREVTFLEASRFAQEN ELMFLETSALTGENVEETFLKCARCILTKIESGELDPERMGSGIQYGDASLRRLTSKRPD CSC-IQPSSKEKLDTSQWPLLLKNFDKLNVRTAHYTPIPSGCSPLQRPITDYVKAGCINL DKPANPSSHEVVAWIKRMLRVEKTGHSGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYV CIFRLHSAVENEKKVNQAIETLTGALFQRPPLISAVKRQLRVRTIYESKLLEFDKERNMG ILWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGIQSEKDGLVTMHDILDAQWLYD HHKDETYLRRVIKPLEALLVSHKRIILKDSAVNAVCYGAKIMLPGVLRYDDGIEVNDEIV IVTTKGEGIALAIAQMTTAVIATCDHGIVAKLKRVIMERDTYPRKWGLGPVASKKKQMIK AGLLDKHGKSNEKTPTDWSTSYVDLSKALKRKHEPPTTSSEKKKKKKK------------ ---------AVNQAQRQGLDIETSKKFNAGHNKQNAAAKDTAKLDRETEELHHVTIGLDV GRLIQQGRQEKKMTQKELATKVNEK-----------------VIGKLERAVGLKLRGKDK GKPLEARMLKPKALTQVLAQANTGGVQSTLLLNFEGALLAFSGYGDKDARITAAITSNIW SAYEKTGKAAFNEDDLKLILLECEDGKVAITKVANLLLCIYAKESVGLGILKAKAQALAS YLEEPLTQVAASSSATARIQTKKQTLDDAYAPPANFLEIDVLNSQGKKRYTDYEVRMRTN LPVFKVKESSVRRRYSDFDWLRQELERDSKIVVPPLPSKAWGRQLPFRGDDGIFDDDFVE DRRKGLEQFVNKVAGHPLAQNERCLHMFLLEPIIDKNYVPGKVRTTRAMSARLSEVGVLE TPKVQGKYETGQLFLHKVFGYRGVVLFPWVVKVYDRDIAANTSKEVKGRTHTYYQVLIDS RDMPHIRVGTESVTFLNNQNQASIFSIPGLDYVGHEDVLPYKTTDKAPIENHLFDKFLML DENFAARNHLSEWQDQYFPWLELTEVHKETTEDIRVTVMPFYIGETHRDRVYWWRYCIRM ENIGEQTVQLRERHWRIFSLSGTLESTRGRGIIGKEPIFSKQSPAFQYTSHVSLQAPSGH MWGTFKMERPDGSTYECRIPPFSLESKQVDFMATSKGANTYNRQNWEDSDFPILCQTCLG DNPYIRMTKEKWGKECKICVRPFTVFRWCPGARMRFKKTEVCQTCSKIKNVCQTCLLDLE YGLPVQVRDAALKVQDEMPKSDVNKEYYTQNMEREIANSEGTGPVGTLGKAQAPSDMLLK LARTTPYYKRNRPHICSFWVKGECKRGEECPYRHEKPTDPDDPLADQNIKDRFYGLNDPV ADKLTKRYTAMPKLEPPEDMDVFLMIRHKKSTVFLDAKESNSVLELKTAVTGITKKAPED MRLFREHKSLADSGYTSSMARAQAPATVGLAYREFEELEIAPLSTPPELPDVMKPQESAS SHA--HLMRYHSVLLRARFDENKDVDPRIAKKLLQDGEHELFLKMHPQPFKFPNSPGGQA YGREPRDPDWMLDMWHPLERAAYPEYFAKRDQRKIEFIKAYEEKYGKAEMEDYIKIEKIG EGTYGVVYKGKNKKTNRTVALKKIRLESEEEGVPSTAIREISLLKELQHPNIVCLEDVLM QENKLYLVFEFLSMDLKKYMDSIPSGQYMDKMLVKSYCYQILQAILFCHQRRVLHRDLKP QNLLIDSNGVIKLADFGLARAFGIPVRVYTHEVVTLWYRAPEVLLGSPRYSTPVDIWSIG CIFAEMMTKRPLFHGDSEIDQLFRIFRTLTTPTEESWPGVTSLPDYKPTFPNWKSNTLAQ SVDPSGLDLLLKTLVYDPAVRISAKGALQHPYFAARLFNRIGALGLTVAVGAGVINSALY NVDGGHRAVIFDRFQGVKQTVIGEGTHFMIPWVQRPIIFDIRSRPRSVPTITGSKDLQNV TITLRVIFRPLADRLPLIYTNLGIDYDERIMPSIVNEVLKAVVAQYDAIELITQREAVSM KISEELTNRAAQFGIVLDDIAITHLAFGKEFTEAVEMKQVEQQSAERARYLVEREEQRKI AAIIRAEGDSRAAELLAKAFGEAGEGLVELRKLEAAEDIAYQMSQSPNVVYLPERQQTLL ALP-------QTVTIPEGIEFAVKSRKVTIKGTRGTLRRNFAHLAVDIKKIGKNKILVEK WFGIXKELAAVRTVCSHIENMIKGVTKGYKYKMR-------------------------- --------------CEASKAQKDEFILQGNDIELVSRSAALIQQSTTVKRKEIRNFL--- -----------MGCAVSSEDKLAVERSKQIDKSLRQDGEKASREVKLLLLGAGESGKSTI VKQMKIIHEKGYSQDECLQYKPVVYSNTIQSMIAIIRAMGQLKIDFGHPDRADDARQLFA LAGNAEDGELTPELASIMKRLWKDSGVQECFSRSREYQLNDSAEYYLNALDRLCEPNYVP TEQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFIVAMSE YDLTLAEDQEMNRMMESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICFPE FSGANTYEEAAAYIQVQFNKRKDTKEIYTHFTCATDTNNVQFVFDAVTDVIIKNNLKDCG LFKKFAEMKRMINLKDTRIKKKDRETKKRKKADPQNMKIREIPQSSSALFFKYNEQLGPP YHILVDTNFINFSIKNKLDIMQSMMDCLFAKCIPYISDCVMAELEKLGSKYRVALRIAKD PRFVRLPCMHKGTYADDCLVQRVTQHKCYIVATCDKDLKRRIRKIPGVPIMYLSQHRYSI ERMPDAFGAPK------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------PSAPLILASASFDSTVRLWDVERGQCIHTLTRHQEPVYSVAFS PDGKFLASGSFDKCVHIWNVQTGALVHSYRGTGGIFEVCWNHRGDKVGASASDGSVFVLD LRKSNSDLATLFECPVCFDYALPPIMQCQSGHIVCSSCRPKLSLCPTCRGPLGNIRNLAM EKVASQVMFPCKYSNSGCLVTLQHTDKTEHEEVCEFRPYCCPCPGASCKWQGSLEQVMHH LMQQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGNQQFYA IVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHDGVQSAINNSDCLVFDTNIAQLF ADNGNLGINVTINMCMAYQTFQQEYMQMPPITRAYTTACVATTLAVQLDIITPFQLYFNP DLIFKNIQIWRLVTNFMFFGTIGFNFLFNMIFTYRYCRMLEEGSFRGRTADFLFMFLFGG FLMTLVVNLVFLGQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPYLPWVLLAFSLLLGNS IVVDLMGIAVGHIYFFLEDVFPEQRGGFKLL----------------------------- ----------------------------------------------------YGPHEVRG SRSKHEKAIINCQFSMAVFSTGERKRRPRGDRKSNEMAQHLKQTFEAAIVTNLYPRSQID IFVEVLQADGGNYCACVNASTLAVIDAGIPMKDYVCASSSSFLNDTPIVDMNHLEESSGP EMIVATLPKSDQIVFLEMNSRLHEDHLSKVVDMATKGCKDVYNILDRHVREMAGTYYFVI VGHHDNPVFEMEFVPPNKANDPKKDDHRHLNQFIAHAALDLVDEQVWTHNNMYLKIVDKF NEWFVSAFVTAGRMRYLMLHDVKNEDGIKNFFQETYETYVKHSMNPFYEPNSPIRSTAFE KKALLYGRKYL--QVRLAHTDIKVPDFSAYRRESVKPTRNAFTYLLVAGGAVPAAYAAKT MVTSFVQSMSASADVLALAKIEVKLSDIPEGKNATLKWRGKPLFIRHRTAEEIERERAVD ISTLRDQQTDEERATRPEWLVLIGVCTHLGCVPIANAGEYGGYYCPCHGSHYDASGRIRK GPAPLNLEIPYHEYPDDDNVVVGMSRQASRTTDPRKVSGELFTLTYGSLVAQLLKDYESD EEVNKQLEKMGYNIGVRLIEDFLARSNSGRCHDFRETSDVISKVGFKMFLGVTPVVTNWS AAGDEFSLLLENNPLADFVELPEGHSNLNYSNILCGALRGALEMVQMDVAVSIVQDQLKG DNITEIRLKFIKRLEDAVPAGEDENVKAFLAQAKEDFNKKWEEPAQNTASLDDFDRIKTL GTGSFGRVMLVQHKATKSYFAMKILDKQKVVKLKQVEHTLNEKRILQAISFPFLVGLEYS FKDNSNLYMVLEFVTGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKP ENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVY EMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLRNGVN DIKNHKWFLTTDWIAIYQKKVEAPFIPKCKGPGDSSNFDDYEEEPLRISSTEKCSKEFAD FMLADTLLIVFISVATAFLGEGLTWLLVYRTEKYKKLKAEVEKQSKKLEKQKEALGQATE RSQKKKLERQEEKLKNNNRDLSLVKMKSMFAIGFAFTALLSMFNSIFDSRIVAKLPFTPI SWVQGISHRNLIGEDFTDCSFIFLYILCTMSIRQNIQKLLGFAPSRAASKQGGGFFSTCV KYFDCWSEVEQVSFVEHLLSRMCHYQHGQINTYLKPMLQRDFISALPAKGLDHIAETILS YLDAKSLCAAELVCKEWLRVVSDGMLWKKLIERMVLTDPLWRGLSERRGWGQYLFRPKPG ESPKDNKFYRRLYPQIIQDIERIENNWRTGGHTLQRIHCRSETSKGVYCLQYDDQKIVSG LRDNTIKIWDRNTLECVQVLTGHTGSVLCLQYDENIIISGSSDSTVRVWSVKTGEMLNTL IHHCEAVLHLGFSDGIMVTCSKDRSIAVWDMQSPTDINLRRVLVGHRAAVNVVDFDQRYI VSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACL RVLEGHEELVRCIRFDSKRIVSGAYDGKIKVWDLAAALDPRAPAGTLCLRTLVEHSGRVF RLQFDEFQIVSSSHDDTILIWDFLNMAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNS TFISTIGIDFKIRTIEMDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKS FENIRNWIRNIEEHASTDVEKMILGNKCDMNDKRQVSKERGEALAIEYGIKFMETSAKSS INVEESFFTLARDIKAKMDRKLSDGETSADRNVEIWKIKKLIKSLEAARGNGTSMISLII PPKDQISRVAKMLADEFGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVIYCGT IVTDEGKEKKVNIDFEPFRPINTSLYLCDNKFHTEALTALLADDNKFGFIVMDGNGALFG TLSGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAEVAVQLYITTDRP NVAGLVLAGSADFKTELSQSDMFDPRLQAKIIKIVDVSYGGENGFNQAIELAAEALSNVK FIQEKKLIGKYFDEISQDTGKFCFGVDDTLKALEMGSVEILIVWENLDIQRYVLKNHQTD EEKILFLKPEQEKDKTYFTDKETGVELELVESMALLEWFANHYKSFGATLEIITDRSQEG AQFVKGFGGIGGILRYQVDFQQLDLLNELGADFDLDEY---------------------- ------------------------------------------------------------ ------------------ESSGWLKHIKSIIDTSVFIAKAI-CEGVSVLVHCSDGWDRTA QTCSLSSLMLDPYYRTIEGFQTLIEKEWLSYGHKFTDRCGL-LGMIDPKEVSPVFTQFVD GVWQLMLQFPMAFQFNERYLLTLHDHVYSCQFGTFIGNCEKDRIDLRLRERTYSLWGYME KYRSDFLNPFYQPLIIPVLNPQSVKFWRGLYCRFDSGIHPRESV---------------- -------------SPFKPFIPHLPFDLVQCESAFPNSKTPPDEKSMADALLKRAQELTPS AQEQTAVLNVVTKITSVLDNLVVAPGTFDAAQLDEVRQVGSHKKGTMMAGHNVADIVVIF KTLPTVEAVQALGNKVTEELRQSEPHEVLTMLTNDSGFEISSSEATVKVLITTIPPNLKK LDPDLHLDGKIMQGHLAAIRHARWFEENAFHSSIKVLIRLIRDLLSRFEGFEPLTPWIID LLAHYSIMNNPTRQPLPVNVAFKRCLQLLAAGFFLPGSAGITDPCEQGNVRIHTVMTLEQ QDMVCCTAQTLLRVLSHGGYKQILGLEGNSSIATEMSVWEGVVVTPSDKAYEKPEKVVRL IEQYMKENNLMRTLAILQDESGISLNTVDSVDSFVSDINNGHWDTVLTAMQSLKLPDQKL LDLYEQIVLELIELRELGAARSLLRQTDPMIMMKQQYPDRYLHLENMLARSYFDPREAYP EGQTKERRRAAIATALAGEVNVVPSSRLLALLGQALKWQQHQGLLPPGTTIDVFRGKAAV KEQEEEKYPTQLSKSIKFGQKAHIECTRFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLK YQAQDNFMMMDDAVLCLCFSRDSEMLSTGGQDGKIKVWKISTGQVLRRFERAHTKGVTSI CFSKDNSQILSASFDQTIRIHGLKSGKALKEFRGHTSFVNDAQFAADGHHIISASSDGTI KVWNIKSTECQNTFKSLGGTAGTDITVHSVHPLPRNVEQFVVCNRSNTVVIMNMQGQIVR SFSSGKREGGDFVCCTLSPRGEWIYCVGEDMVLYCFSITTGKLERTLTVHEKDVIGIIHH PHQN-------------------------------------------------------- --------GRTQKWRQLTVKEAPTRVFTNACWFFIGEIIGKGSLVGYKIDGAYNTHVHAI PKFYFKLPSEDEFLLQKLREESRAVFLQRRSRELLDNDELQGLWFLLDKYHTPPLVGEEQ MINYEDFLKVSAEAGDKCKPFFNASVFAKLLQTDPYGRISIMQFFNYVMRKVWLHQTRIG LSLYDVAGQGYLKESDLENYILELIPTLPQLEGLERSFYSFYVCTAVRKFFFFLDPLRTG KVKIQDILACSFLDDLLELRDEELPKEMQESNWFSAPSALRVYGQYLNLDKDHNGMLSKE ELARYGTGTLTEVFLDRVFQECLTYDGEMDYKTYLDFVLALENRKEPQALQYLFRLLDVQ NKGHLNIFDLNYFFRAIQEQMKMHGQEPVSFDDVKNEIFDMVKPLDPLKITLQDLIKCGQ GDTVGSILIDLNSFWTYENREVEIVRGQVFEVGPRYANLAYIGEGAYGMVVSAYDNVSKT KVAIKKISPFEHQTYCQRTLREIKIITRFKHENIINIQDIIRAGAIDDMKDVYIVQCLME TDMYKLLKTQKLSNDHVCYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFG LARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYSKAIDVWSVGCILAEMLSNRPIYP GKHYLDQLNHILGVLGSPGQEDLNCIINDKARGYLQSLPYKPKVPWNKLADPKALDLLDK MLTFNPHKRITVEEALAHPYLEQYYDPADEPIAEQPFTFETELDDLPKDRLKELIFKETV LLRERQLSPPKTTPEWVKFCKQMFGGFALLLWIGAILCFIAYSIQASTYEDPPGDNLYLG IVLTAVVVVTGCFSYYQEAKSSRIMESFKSMVPQFALVVRGGLKLTIHAEELVIGDIVEV KFGDRVPADIRVVQSHGFKVDNSSLTGESEPCSRSAEYTHENPLETRNLAFFSTNAVEGT CVGIVVSTGDRTVMGRIANLTSGIEMGQTPIAREIAHFIHIITAVAVFLGVSFFIIAFIL GYPWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTI CSDKTGTLTQNRMTVAHMWYDNRIVEADTSEDQSNATYDGSSLTWMALA-----XNRAEF KPNQESVPVLKRECNGDASESALLKCVELSIGKVNEYRAKNKKICEIPFNSTNKYQLSIH GGEQRSLIVMKGAPERILDRCSTILLDGQERPLSEEYRDYFNQAYLELGGLGERVLGFCD YLLPTDQFPQGYPYDPDEENFPLTGLRFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVT GDHPITAKAIAKGVGIISEGNETVEDIAARLGIAVSDVNPRDAKACVVHGSDLRDMTPSQ IDDIIANHSEIVFARTSPQQKLIIVEGCQRQGQIVAVTGDGVNDSPALKKADIGVAMGIA GSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLLFILAD VPLPLGTITILCIDLGTDLVPAISLAYECAESDIMKRMPRDPVNDKLVNNRLIGMAYGQI GMIQAXAGFFTYFVIMCENGFWPSRLFGIREQWDSKAINDLEDSYGQEWTYAQRKVLEYT CHTAFFTSIVIVQWADLMICKTRRNSIIHQGMLNHHMTFGLYFETTLAAFLSFCPGLDKG LRMYPMRWTWWCIPMPFSLAIFIYDEVRKYILRRNPGGWVEQETYY-------------G LTAGAIGVGTALNELHLHAPQYPWSHNGIFSSLDHASVRRGYMVYKQVCAACHSMDYMYY RYLVGTIMDEDEAKTEAADVLVKDGPNEEGKMFDRPGKLSDRFPRPYANDEEGKSANNGA LPPDLSFICYARHGGEDYLFSLLTGYCDAPAGVEVADGQYYNPYFAGGKISMAQALYNEI IEYDDGTPATSSQMAKDVSTFLAWTADIHHDDRKRMGLKTLMVMLTLWFYYMKRHKWTVL KSYKIL--RPDLPSRCTYQLGVLKDSPHRHKARPPKILPTILHRIGETPLVRINKLGKAA GLECDILAKCEFFNAGGSVKDRIGLRMVEDAEAQGLLVPGDTLIEPTSGNTGIGLALASA VKGYKCIIVMPEKMSLEKVDVLRALGAEIVRTPTSASFDSPESHIGVANRLLQEIPNSHI LDQYRNAGNPLAHYDGTADEILTACDGELDMVVCGAGTGGTITGIAKKIKEKCPDCKVVG VDPAGSIIAQPADVNSYEVEGIGYDFMPTVCETKYVDKWYKSYDKPS------------- ------------------------------------------------------------ ------------------DERHGHGKATLPSGDTYEGMYENGKRNGHGTYRFKNSARYIG EWSKNKKHGRGTFIYPDGSKYEGDWVDDQRSNFGKYYYINGDLYEGEWQNHVRHGQGSYM YAETGTKYSGTWKDGKREGQGELIHANHKYVGPFKEDRPEGKGKYVFDIGCQQHGEYIMP DIMRLITKDLSEPYSIYTYRYFIHNWPKLCFLAMEGKKCVGAIVCKLDLHKKMVRRGYIA MLAVDQSARRKGIGSHLVMKAIRAMVADDCDEVVLETEITNKAALHLYENLGFVRDKRLF RYYLNGVDALRLKLWLRTVESLMFHISPNQKKCLKEEIHKDVLVTGDYELSDGPSQITTL KVTDSKGHVLYNKDEAGRGKFAFTTEEYDMFEVCFESRMQNGGHGGEREVFLSMKHGVEA KNYADIAKAEKLKPLEVELKKLEDLSESIVNDFAYMRAREEEMRDTNESTHSRVLYFSIF SMCCLLGLATWQVLYLRRYFKSKKLIEEMESGRTSSVGNDILGFLGEVVNKPDHSGLDWI KICEKSSKVITFIDLAGHEKYLKTTVFGMTGHAPDFSMLMVGANAGVVGMAKEHLGLALA LNVPVFVVVTKIDMCPPNILQETLKMLQRILKSPGCRKIPVLVQSLDDVVVSATNFTSER MCPIFQVSNVTGENLTLLKMFLNLLSTRLTTEPAEFQIDDTFSVPGVGTVVSGTALKGMI KLNDTLLLGPDPLGQFIPIVIKSIHRKRMPVKEVRGGQTASFSLKKSQIRKGMVMVSPQV EPKACWEFEGEILVLHHPTTISVKYQAMVHVGSVRQTATIMTMTQEHLRTGDKAIVRFRF IKNPEYLRHDMRMVFREGRTKAVGTVTKLFPHISCNSRQQRAAKKAQEKEKISQKDDHHF YLFKVLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASGEELHTLEGHRNVVYAIAF NNPFGDKIATGSFDKTCKLWSSETGKCYHTFRGHTAEIVCLSFNPQSVVATGSMDTTAKL WDVICTLSGHSAEIISLTFNTTGNQLITGSFDHTVSVWDKRIHTLIGHRAEISSAQFNWD CSLIATGSMDKTCKLWDACTGQNIGTLRGHDDEVLDVCFDYTGQYLLSASADRVYNATTH SKLEGHEGEISKVCFNPQGTCILTASSDKTARLWNPETGECKQVLEGHSDEIFSCAFNYE GTTIITGSKDNTCRIWRGDVFMEKHWKSVIHRSICDYFFEAQGKAVSPEDVPPVISTPHH YLINIYRKQLFFVAVVMTEVPPLFVIEFLHRVIDTFEDYFNECTESMIKENYVIVYELLD EMLDNGFPLAMESNILKELIKPPNLLRTITDTVTGKSTAVSETLPTGQLSNVPWRRTGVK YTNNEAYFDIIEEIDAIIDKSGSTVFAEIQGYIDCLIKLSGMPDLTLSFVNPRLLDDTSF HPCVRFKRWESEKILSFVPPDGNFRLISYHIGSQNMVAIPVYVRHSISFKEGSSGRLDIT IGPKQAMGKPVENVVIEVPFPKMVLNATLTPTQGKYSFDPVTKLMTWDVGKIDPAKLPNI RGSINIQSGSP-------------------------------QKYKPFKGVKYVTKAGKF QVRTMSSYVKPATRYATSDWFTSNYTISTNAERQRSASHDTRQEGRFLRNETDNKTKWDQ LDNNTRLADRVDHIRKWKDILEKTLADTDQEIRDLSEAKDHLETSLEAKNLPTEVNIENM VTREGRQDIDVVEDEVEDQEHKEQEVISGIKRQLQQKIDESFEQLCVLQEARQQILADLQ DKNIALGIDVDQYNLTEESPNISYKPDPCRVPKGSTTPQQWEDFSRYNKERAEAEMGNSR RLREAIHHTIQQTDNDLESQTTATDYALRKRIHEFQKAIDELNWQKAQTEEEIAEMEEDI RRLNDAIRAKINPMKLAQTRLENRTYRPNQELCRDNPQYGLTDEVKQLEATKKALEEKLK QSQHALDGLEQNLHRINEDLQCKTNSLKLDEQCMKSRERLERNQTLTGMTNLKDQLANAI PEHQRLVTEFRGKHGNTKVGEVTVDMMYGGMRGIKGLVTETSVLDPDEGIRFRGYSIPEC QKVLPSAPGMEEPLPEGLFWLLATGKIPSKEQTAALSKEWANRADIPSHVVTMLNNFPHN LHPMAQFSAAIIACNSESKFAKAYSDGVKKADYWEYIYEDSMDLIAKLPTIAAIIYRNLY RDGTSVSAIDPAQDWSANFVSMLGYEDPKFTDLMRLYLTIHSDHEGGNVSAHTCHLVSSA LSDPYLSFGAGMCGLAGPLHGLANQEVLVFLTSIRYTEKDLKEHVWNLLKSGQVVPGYGH AVLRKTDPRYTCQREFALKHLPNDPMFKLVSNLYKITPDILLEQGKAKNPWPNVDAHSGV LLQYYGMTEMNYYTVLFGVSRALGCLASTIWDRALGLPLERPKSMSTEGLMKLTSXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXDHLFVHRDSPENNPDIPFEFSAENLKRAQAIIGNYPTGHEAAAVIPLLDLA QRQYGWLPIAAMHYVGNMLKMPKMRVYEVATFYTMFNREPIGKYHVQICTTTPCMLGGAG SDVILEAIKQKLGIGPGETTKDNMFTLSEVECLGACVNAPMVQINDNYYEDLTVKDMDEI LDDIKAGKAPKAGPR---NGRFACEPSEGLTSLTEPPYGPGFGVRSDLMQKYEKLEKIGE GTYGTVFKAKNRETQEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLYDVLHS EKKLTLVFEYCDQDLKKYFDSCNGEIDPDVVKSFLYQLLRGLAFCHSHNVLHRDLKPQNL LINKNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIF AELANAGRPLFPGNDVDDQLKRIFKLLGTPSEDTWPGMTQLPEYKPYPMYYVNQQVVPKL SSKGRDLLVSLLVCNPSKRMSAEEAMQQSYFSDLNPAIKSDSKWLPYNGPTPGVSFPQKE VCDGWPIEYLEFHPDQEKAKKWMEDHLSDDMKDMYLKRQTRGGKGVIKAKKKQEEQHICI SRSSRGKKKYVTIVTGLATYDIDLKVASKFFGSRFACGASVTGPDEIVIQGDVKDDLFDV IPEKWKLIDEDNIDDLGDQKRLYASDRSCAWGLMKESLCGTLKAKNSLLYGTPELLHKYY FKPALSQGMMGIRPHGYSGVQVPDKETLVTDAGKLFVLDTLLARLKVEGHRVLIYSQMTR MIDILEEYMWHRKHTYMRLDGSSKISDRRDMVADFQNKSDIFVFLLSTRAGGLGINLTAA --VIFYDSDWNPTVDQQAMDRAHRLGQTKQVTVYRLICKGSIEERILERAKEKSEIQRMV IQGGSFRPEVLRPKEVVSLLLDDDEMERKMDVKTIPKDLRNLRACLLCSLIKTIDQFEFD GCENCDEYLHMKNNRDAVYECTSSSFDGVVSLMSPEDSWVAKWQRINRYVKGCYAVSVTG RLPPGIIRDLKSKGITYRPRDTS-------------DELRQIAKAIASPGKGILAADEST GTIGKRFAQINAENVEDNRRHYRQLLFTALSSYVSGVILFHETFYQKADDGTPFTKVLLD NGIIPGIKVDKGVVPLAGTTGECTTQGLDGLSERCAEYKRDGAGFCKWRCVLKISSHTPS YLAMLENANVLARYASICQQNGLVPIVEPEVLPDGDHDLETAQRVTEEVLAFVYKALADH HVFLEGTLLKPNMVTAGQSSSLKFSPQQVAFATVEALSRTVPPAVPGITFLSGGQSEEDA TIHLNAINQRPWALTFSYGRALQASVLKAWAGKTDNVKAAQTELLKRAKANSEASLGKFT GGAAGAGQESLFV-----YIQSLPKSVKRRIKALKKLQFEMIKIESKFYEEVHELECKYA SQYAPLFERRKNIVTSEVEPTDSDCEXPSDEEDEEDKAKIEEKFNILGIPDFWLTIFKNV DMLADMIQDHDEPILKHLHDIKVKFSMGFTLEFYFGQQEFFVNTVLTKEYVMRSEPDGSD AFGYEGPEIIKCKGCSVDWKKGKNVTVKVIKKTQKHKGRGTKRTVTKTVQNDSFFNFFSP PEVPDGEPDEDTEALLAADFEIGHFIRERIVPRAVLYFTGEALE-----------IILLK DGTDSSQGKPQLISNITACQAIVDAVRTTLGPRGMDKLIVDNNGKATISNDGATIMKLLD VIHPAAKTLVDIAKSQDAEVGDGTTSVVLLAGEFLKQCKSFVEEGVHPQIIVRAYRKATY LAVEKMKEIAVQIPKDPKQQRDLLIKCAATALSSKLVARQKDFFSVMVVDAVLSLDELLS LDMIGMKKVQGGSLEDTLLVSGVAFKKTFSYAGFEMQPKKYENPKIALLNIELELKAEKE NAEIRVDNVEEYQAVVDAEWTILYDKLEKIHLSGAKVVLSKLPIGDVATQYFADRDMFCA GRVPDEDLKRTLQACGGSIQTTVTNITLGTCECFQESQIGGDRFNFFSGCPKAKTCTIIM RGGAEQFIEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSRYLRDYSRTIAGKEQLL IGAMAKALEVIPSQLCDNAGFDATNILNKLRQKHAGMWYGVDITTEDISDNYEACVWEPS IVKINALTAASEAACLILSVDETIKNPKANQEPAGRGRGRGRPM---------------- -----------RAGRGFTLEELKAAAIMPRPVAGPLRPIVRCPTLKYNRRVRAGRGFTLE ELKAAGINKRVAGTIGIAVDYRRRNSSVESLQMNVQRLKEYRSKLILFPKKLSKPKKGDA TEEEIKMATQLAGKVMPITEVFKKEKARPVTADMAKHQAFVVLRQAQANKKLKGAREKKA REAMPNIKVFSGNSHPDLAQKVSDRLGIELGKVVTKKFSNQETCVEIGESVRGEDVYIIQ SGCGEVNDMLMEMLIMINACKIASASRVTAVIPCFPYARQDKKDKSPISAKLVANMLSVA GADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKDNIPEWRNSCIVSPDAGGAKRVT SIADKLNVDFALIHKERRKANEVASMVLVGDVKDKVAILVDDMADTCGTISHAAQKLLEA GAIKCFAICTHGILSGPALTRINDSQFECVVVTNTIPQEEKMKRCSKLQCIDISMIMAES IRRTHNGESISYLFAHVPILTCRFYEHKFPEIEDVVKVNVRSIAEMGAYVHLLEYNNIEG MILLSELSRRRIRSINKLIRVGRSECVVVIRVDKDKGYIDLSKRRVSPEEIMKCEEKFAK ANCVNSILRHVAELLKYETEEQLEDLYMKTAWFFDRKYGKPGSSYEAFKHAVTNPEILDE CELDADTRRVLVNNIKRRLTPQAVKIRSDVEVSCFAYEGVDAVKNSLRAGLDLSTEDMPI KINLIAPPLYVITTTTLERSDGMARGQQKIQSQQKAAEKAAKLKHDQKKAAAAALNYQCP VCKTKMGDLKTYKMHFENKHPKSPLPEELKEVMLGNLNTDLNKQGIMTVPKGHCAACAKP IVGQVITALGKIWHPEHFTCVQCKEELGTMNFFERDSQPYCERDYHNLFSPRCSYCQGPI LDKCVTALGGTWHPEHFFCAECGRPFGDDGFHEKDGKAFCRDDYFEKFAPKCGGCNKPIM DHYISALNRQWHAECFICTECRMPFGASSFFDHEGMPYCETHYHARRGSLCAGCHKPITG RCITXMYKKFHPEHFVCAFCLKQLNKGTFKEQNEKPYCHPCFVKLFMRPLTDEETKTFFE KLSKYIGENIRLLIDRPDGTYCFRYHKDRVYYVSEEIMKKAGNVARENLVSFGTCFGKFT NSGKFRLHITALDFLAPYSKYKVWLKPSAEQQFLYGHHIMKSGLGRITENSSQYQGVVVY SMNDMPLGFGVTAKSTAECRHADPMTIVCFHQADIGEYIRSEDTLAEHRKLFVGGNWKMN GDKKTIDGLVQILNEGNPNTDVVCAPPAVYLDYVRHKLIGVAAQNCYKAEKGAFTGDISP GMIKDVGCGWVILGHSERRHVFGESDKLIGEKVAYALSQGLQLIPCIGEKLDEREAGKTE EVVFRQTKATDWSKVVLAYEPVWAIGTGVTASPDQAQAVHQSLRKWLAANVSPEVAKSVR ILYGGSVTAGNCRELAQCPDIDGFLVGGASLKPEFINIINAREREGLLDPAWEKQQKKTF TAWCNSHLRKAGTQIESIEDDFRNGLKLMLLLEVISGEQLPKPDRGKMRFHKIANVNKAL QFIESKGVKLVSIGAEEIVDGNLKMTLGMIWTIIVKNFHMSFKDGLAFCALIHRHRPELL DYHKLSRDNPLENLNLAFDVAEKHLDIPRMLDAEDMVNSVKPDERSVMAYVSSYYHAFSG AQQAETAANRICKVLKINQENERLMEEYERLASDLLEWIRRTTPWLENRTTDNTLPGTQR KLEEFRDYRRQHKPPKLEQKAKLETVFNTLQTRLRLSNRPAYLPTEGKMVSDIANAWKGL ERAEKGFEEWLLSELQRLERLDHLAQKFKHKCDIHEEWSYGKEDMLQAQDFKKCRLNELK AMKKKHEAFESDLAAHQDRVEQIAAIAQELNALGYHDVQTVNSRCQRICDQWDLLGTLTT QRRNALEEAEHILERIDQLHLEFAKRAAPFNNWMDGAKEDLVDMFIVHTTEEIQGLIDAH EQFKMTLGEADKEYNAIISLVQEVSRLANQYGIQGADVNPYSTLQAQDIASKWKDCKALV PQRDSTLQSEMVRQQNNERLRRQFAQKGNVVGQWIERHLDMVASVGVQKGSLEDHLAKLH GIEKEVYAFRPNIEELERYNQEVQEAMIFENRHTPYTMETLRVGWEQLLTSVARNINEVE NQILTRDSKGISNEQMEEFRKSFFHFDKTRKRRLEPKEFKACLISLGYNIRDDRQGEADF QRIMSIVDPNGLAYVTFDAFLDFMTRETTDTDTAEQVMQSFRILAGDRPFITADILRREL PPDQAEYCIQRMAPYTGPDGVHGALDYSSFSTALYGESDL-------------------- ------------------------------------------------------------ -----------------EVEAACANPATGSVILLENLRFHLEEEGKGVDADKKKVKADPA KVTEFRASLSKLGDVYVNDAFGTAHRAHSSMVGCQLPQKASGFLLKKELTYFAKALESPE RPFLAILGGAKVADKIQLIENMLDKVNEMIIGGGMAFTFLKVINNMEIGNSLYDEDGSKI VQKLMDKAKANNVQIHLPSDFVTGDKFAEDATVGSATVSSGIPAGSMGLDIGSETIKKNM EVIGRAKTIVWNGPPGVFEFANFANGTKGMMDAVVHATSKGATSIIGGGDTATCCVKFGT EDKVSHVSTGGGASLELLEGKNLPGVAALSDAMAGIPPKTWQPQNVTLETTMGSIVVELY WKHTPNTCRNFAELARRGYYNGVKFHRIIKDFMIQGGDPTATGRGGASIYGKNFDDEIHF DLKHTGAGILSMANSGPDTNGSQFFISLAPTQWLDDKHTIFGRVSSGMTVVSRMGMVECD TNDKPLEDVKILRKRGSSREPKRSRSTD-RKKPHKYWDVPPPGFEHITPLQYKAMQAAVS EMNNQKIRQARRLYVGNIPFGVSEDMMIEFFSTQMKLAGLAQAEGNPVIACQVNLDKNFA FLEFRSVDEATQAMAFDGMEFQGQSLKIRRPRDYQPLPGMAETPSVGVVSTVVQDSPHKI FVGGLPNYLNEDQPRELLTSFGPLKAFNLVKDSATGLSKGYAFCEYLDQACAGLNGMQLG DKKLIVQRASVGAKNAQQAPVQIQIPGLNMNQVPTEVLSLMNMITPDELEDEEEYEEILE DVKEECGRYGNVKSIEIPRPIQGVEVPGVGKIFVEFNSIIDCQKAQQALTGRKFSNRVVV TSYFDVDKYHRREFFVPLFDRVLVQRFAAEAKTKGGLLIPEKAQGKVLEATVISVGPGSR KDNGDVVAVSVKPGDKILLPEYGGTKVQIQEEDYFLFRDGDILGKFERLKAQIPDIRTSL NIVKHMKSKKDSLDTHFQLSDNLYARAKIPPTDKVCLWLGANVMLEYNLEDADSLLKKNA AVTSLEQLEDDLGFLRDQTTTIEVNMARVYNWDVKRRQ------DEALAKAGLHFDELNK IRVLEPEISTQTTELKEECKEFLDKMQEFKGIVGTFISLIDEVSKEVEKEKMKAIGSRNL LKSITKQREAQQQQLHALIAEKKMQLERLRIQHTALIREEQDQNEFIDQFILQKRDRDRD RDRDKDKRKRSRSQERGDLTPEERDARTVFCMQLSARIRPRDLEEFFSSVGKVTDVRIIT DNKTRRSKGISYVEFKDVDSVPLALGLGGQRLLGVPIMVQASQAEKNRQAGNTGPMRLYV GSLHFNITEDMLRGIFEPFGKMEEVKLIKNHETAHSQGYGFVTFHNAEDAKKALEQLNGF ELAGRPMKVGHVTERTADTSILDSDEMDRAGIDLGATGRLQLMAKLAEGTGFQIPQVAAN ALSMAPVNQTPPIATQCFMLSNMFDPATTTVNWDVEIRDDVIEECNKHGGVLHIYVDKAS PQGNVYVKCPSISAAVASVNALHGRYFAGKVITAAYVPLPNYHQLFPEALRANQLLLTSS ------------------------SAEVYTEEDAASYVKKVVPKDYKTMAALSKAIARNV LFTHLDDNERSDIFDAMFPVHRHRDEMIIRQGDEGDNFYVIDQGEVDIFVNNDYISTISE GGSFGELALIYGTPRAATVKAKTDVKLWGIDRDSYRRILMGSTIRKRKMYDDFLAKVSIL ESLDKWERLTVSDSLEPVQFEDGTEIVRQGEPGEEFFIITEGTASVLQRRSENEEPVEVG KLGPSDYFGEIALLLDRPRAATVVARGALKCVKLDRGRFERVLGPCSDILKRNIAQYNSF VSLSVASYKGLAKLYRLMYIADHGLAYVLTTFNTNMYQQIHKKLQEAITSNVPALDTQWI ETTTKKAALKLEKLDTDLKNYKSNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDY CTSAKHVINMCLNVIKVSVYLQNWSHVISYVNKAEGTPQVSEGKESGQAVMTKLKCAAGL AELATKKYKSAAKYFLQASFDHCDFPELLSPNNVTTYGAFCGLASFDRQELQKLVIGSST FKLFLELEPRLRDILHQFHDSKYASCLKLLDEIKDNLLLDMYLAPHVNTLYVKIRNRALC QYFSPYLSADMRKMAAAFNTTVVALEDELMQLILDGQINARIDSHNKILYAKDIDQRSTT FEKSLHMGVEYQRRTKALILRSAMLKNQIQVKSPPRDGGQGGEMSLPPGNAAGMSQKNEL LNKAEEVADQVLRHGKHILPHVARLCLISTFLEDGIRMWFQWYEQRDYINATWGCGWFLA TMFVVINLLGQLGGCVMVLSRKKVSIACGLLFGIIAMQTVAYSILWDLKFLLRNLALSGG VLLLMAESKAEGKSLFAGLPSLGENTPKTYLMLSGRILLVFMFLTLLRFEFSLLHTMQNI LGTALVLLILVGYKTKLASLLLVIWLTVLNFYMNAWWNIPDYKPMRDFLKYDFFQTLSVV GGLLLVVALGPGGYSMDEHKKKW------------------------------------- --ANRVCLKGIIASPLKTLNMKMRNQLDLFANVVRIRSLPGYLTRHNDLDFVIIREQTEG EYSALEHESVPGVVECLKIITRANSQRIAKFAFHYAIKHGRKKVTAVHKANIMKLADGLF LDTCTEVSRLYPNIEFETMIVDNTCMQLVSNPHQFDVMVMPNLYGNIIDNLAAGLVGGAG VVPGESYSSDVAVFEPGARHAFAGQAGQDLANPTGILLCAANMLKHMHLEHYGQLIQTAV EKTIMSGKVRTPDMGGYGTRSDFTMDVIKNLSEDFQRFMDRSSRVIERALYEEVNVFAEY AGEESEDGLGEGEKLKLNRQFYDERWSKHRTVTCMDWSVQYPELLVASYNNNEESPHEPD GVVLVWNIKYKKPTPEYVFHCQSAVMATCFAKFHPNLIIGGTYSGQIVLWDNRSNKRTPV QRTPLSASAHTHPVYCVNVVGTQNAHNLISVSTDGKMCSWSLDMLSQPQDSMELQHKQTK VAVTSFSFLSGDVNNFVVGSEEGAVYTACRHGSKAGINEMFEGHQGPVTGLDCHTVPGQI DFSPYFITSSFDWTVKLWNIKEQKALHSFEDNSDYVYDAKWSPIHPALFATVDGMGRLDM WNLNLDTEVPTASTTAVAVNKCRWHQSGHSIAVGDDVGKIHIYDVGEPLSQPRNDEWAKF AQTLQEMKNNQAEAEEDQVEQTLLNAAQAAEQQVDAELQKLEKMDEDDYDVLRQRRMLQL KKAQSQKQDWLAQGHGKYEEIADEKEFFEASKKSKNLVCHFYRDVTFRCKIVDKHLAILA TQHLETRFIRIDAEKCKFLIDRLRIVVLPTICLAKNGKTVDYVVGFDDLGGRDDFPTEIL EWRIARADVINYSGDLLTPPVVDHSKKTIRGGDDDSKALHLIGAGGYDKMKVVQLPTPGN GEVLVNVKASGINFAELMCRQGMYDRTPKLPAILGLEGSGDVVELGQGCSKLKVGDRVIC MKGLWSEYCVQCFVMPEKMSYEEGAALPVNYITAYHMLFDFGNLRKRKSVLIHMAAGGVG IAATQLCKTVPEVTVFGTASAKHEMIQANGVTHPIDYRTKDYANEIRKISPNGVDIVLDP LNGADATKGYSLLKPLGKIIHFGAANTVSGPERSYWNILKTYMGQKNYSPLFMISSNKSA AGYHLGHLVAVRDLIDLFNEDKIKPHIDSVWAFEDIGKAMAQMHDRKNIGKVVICPQQ-- RKQTPSDFLKQIIGRPVVVKLNSGVDYRGVLACLDGYMNIALEQTEEYVNGQLKNKYGDA FIRGNNVLYISTQKRRVMANQQAALLLRRQLAELNKNPVDGFSAGLIDDDDIYRWEVLII GPPDTYYEGGFFKCHLIFPKEYPHKPPKLTFKTEIWHPNIDTAGGVCISILHEPGEDKYG YERPEERWLP-------------------------------------------------- ---TVRPQNLVIRQNLADFGKYVGECMPKYVQKVEVTNGEELDVMIHPDGIIPVMTFLKD HTNAQFESIVDVVGVDIPTRQNRFEIVYIFLSLQYNARIKVKTYTDELTPINSISNIYKG AIWYEREIWDMFGVFFANHPDLRRILTDYGFEGHPFRKDFPLSGYVEVRYDDEVKRVVVE PLELAQEFRKFDYNSPWEAFPKFRE-LNPFCQVDYRAKIWSCNFCFQRNPFPPQYASISE QHQPAELIPQFSTIEYTLTRATTNPPVFLIVLDTCMDEEDLQAVKESLQMSLSLLPSNAL IGLITYGKMVQVHELGCEGCSKSYVFRGSKDLNAKQIQEMLGIGRGSGQLPANRFLQPVH KCDMALTDLLGELQRDPWPVAQGKRPLRSTGVALSIAVGLLECTYPNTGARVMLFAGGAC TQGPGMVVGDELKHPIRSHHDIEKDNCKYMKKAMKHYEALANRSANNGHIIDIYSCALDQ TGLHEMKYVSNLTGGHMVMGDSFNTSLFKQTFQRVFSKDVKNEFKMALNGQLEIKTSREL KVQGCIGSCVSMGSGVSVSDTELGVGGTCQWKMCGFYPNSTYAFYFEVVNQHNAPIPQGG RGYIQFITQYQHSSGQKRVRVTTVARNWVDASINNQHIAAGFDQEAAAVLMARIATFRAE TDEGPDVLRWLDRMLIKLCQKFGDYHKDDPNSFRFSEQFSLYPQFMFHLRRSQFLQVFNN SPDETSYYRHRLMIEDLTQSLIMIQPILYAYSFNGPPEPVLLDTSSIQPDRILLMDTFFQ ILIYHGETVSQWRKSNYQDLPEYENFKQLLIAPIDDAQEILKTRFPMPRYIDTESGGSQA RFLLSKVNPSQTHNNMYSDGGGHVLTDDVSLQVFMEHLKKLAVSSASMSTLSHEEQLKLI SDLEIEMMADMYNRMTNVCQKKCVPPKYKDTELNKGEAVCLDRCVAKYLDIHERIGKKLT AMSMQDEETVRKMQA-----------MVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYR KKVVLDGEEVQIDILDDYAAIRDNYFRSGEGFLCVFSITEPESFQASSEFREQILRVKND ENIPFLLVGNKMDLEDKRQVSVEEASAKAQQWNVSYVETSAKTRANVDKVFFDLMRLIRT MKQNDGKKKRKCIILKLYTGLREVVTDHLIHKVREDVLGSLNNNFLQTLNSSWNDHQTSM VMIRDILMYMDRVYVQQNTVDNVYNLGLMIFRDQVVRYPVIRNHLRDTLLDMVAKERRGE VVDRGAVKNACQMLMILGIDSRAVYEEDFEKPFLEQSAEFYKLESQTFLGENSASVYIKK VEARINEEAERATHYLDKSTEEPIVKVLEEELISKHMKTIVDMENSGVVHMLKNNKTEDL GCMYKLFIRVLNGLKTMCECISGYLREQGKALVAEEESAKNAINFVQSLLDLKDRFDHFL HESFNDDRLFKQMISSDFEYFINLNTKSPEYLSLFIDDKLRKGVKGMSEQEIENVLDKSM VLFRFLQEKDVFERYYKQHLAKRLLLNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFKD MTVSNTTMEEFKTHVMQGTNLYGVDLCVRVLTTGFWPFQSASSKCNIPYAPRMAFEAFRR FYLGKHSGRQLSLQPQHGSADLNSMFYGAKKGEPNTSKGPRKHIIQVSTYQMVILMLFNN RDKWTYEEVKNESDIPERDLMRAVQSLALGKITQRVLTKEPKTKEIEPDHLFMVNDQFTS KLYRVKIQTVAAKGESEPERKETRNKVDEDRKHEIEAAIVRIMKSRKRMQHNVLVAEVTE QLKIRFLPSPVVIKKRIEGLIEREYLARTPEDRKIYTYVADRIQVFPSRMAMTQMKSRLK GAQKGHSLLKKKADALRLRFRQILKKIIETKSLMGDVMKEASFSLAEAKFTMGDFNHLVL QNVNKAQIKVRTKKDNVAGVSLPIFENYQDGSDSYELTGLSRGGQQIDRLKKNYAKAVEI LVQLASLQTSFVTLDEVIKITTRRVNAIEHVIIPRIERTLAYILSELDEREREEFYRMKK VQKKKAEIR--------------PLRVLVTGAAGQIAYSLLYSVAKGDVFGLNQPISLVL LDIEAMMGVLKGVVMELMDCALPLLVDIVPTSDVVAAFKDIDVAILVGAMPRREGMERKD LLKANVRIFKQQGEAINLHAKKNCKVVVVGNPANTNAFICKKYAPSLPPENFTALTRLDQ NRAAAQIAARLDVSKVIIWGNHSSTQFPDVRHALVVPAAVKDDNWLKTDFISTVQKRGGA VIAARKLSSAMSAAKAICDHLRSWWTGTPEGQWVSMAIPSDGYGIQQGLIYSFPVQIDHS YSVVQGLEIDDFSRQKLDATMQELIEERDDAL---SGNSGVLMVGPNFRVGKKIGCGNFG ELRLGKNLYNNEHVAIKLEPMKSRAPQLHLEYRFYKQLGQAEGVPQVYYFGPCGKYNALV LELLGPSLEDLFDLCDRKFSLKTVLMTAIQLITRMEYVHSRHLIYRDVKPENFLIGRQSN KKQHIIHIIDFGLAKEYIDPETNKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEAL GHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEELATYLRYVRRLD FFETPDYDYLRKLFTDLMAKNGWDSDWDFDWTGRQLRHGGSVQVVSSTNGELGGTAGHSN TPITAPAEVEVVDETKCCMTTLRPFTCDDMFRFNNVNLDPLTETYGLPFYMQYLAHWPEY FQVAESPSGEIMGYVMGKAEGHTDNWHGHVTALTVSPEYRRLGLAAKLMNILEEISEKKD CYFVDLFVRVSNKVATDMYHQLGYTVYRRVLEYYSGEQDEDAFDMRKALPRDVEGKSVVP LPHPVRPEELEQQLDCALDLMRRLPPQQIEKNLSDLIDLVPSLCEDLLSSVDQPLKIARD KTVGKDYLLCDYNRDGDSYRSPWSNTYDPVLEDGAMPSERLRKLEIDANSAFDQYREMYF DGGVSSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRSAHYKLTST AMLWLQTNKMGSGTMNLGGSLTRQVEADSNVNDSNPHIANIGRMVEDMENKIRNTLNEIY FGKTRDIVNGLRSVKPLQMKMLQDDLANALKNRS-------------------DQVDILA AEERVDPEKRMTTPYMTKYERARVLGTRALQIAMCAPVMVELEGETDPLEIAMKELKARK IPIIIRRYLPDGSYEDWGIDELIIADKSPTLKERIMAPGGESAFTAGRGLVAGASIVGIG ALCYYGLGLSNQVGTIDRAALWPDIVRKRVKDTYMYFGTSLVFTAISRSPRMMNLMMKNS LVALFGTIAAVIGTGALVRSIPYQEGAKQMAWILHAGVIGAVIAPLTLMGGPILVRAACY TAGIVGGLSTLAVCAPSEKFLNMGGPLAMGLGVVFVSSIGTAFLPPTTALGAGLYSVALY GGLVLFGMFLLYDTQKIMKRAETHPVYASQPFDPINNSVGIYLDTINIFIRMATILAGGG GRRKMEIVYVYTKKRAEFGRQCNFSDRPAELHVDIAPDASLIENFIERNPIDSGIQCVQE MSEHEVNTERFETDTRGINHTEGGWPKDVNPVEIEQVMRYRKKVEKDEMYVNTVLSLAGV MENCIRQNNAIDIYEEYFDDVDVDAADEPPSAKTINVFRDPNELKRTATHISWFPDGPKK LAIAYCNLEFQGSSPDTMESYIWDVENPNKPEMTLKPVSPLVSLEYNPKDPHVLIGGQYN GQIAYWDTRKGSQPVEMTPIEYSHRDPAYKVIWLQSKTGTEAFSASTDGQVLWWDTRKLG EPTEILYLDPTKKQDFSKAMGAMSLEYEPTIPTKFMVGTEQGSIMACNRKAKTPAEKIVA IYPGHHGPVYSLQRNPFFPKNFLSIGDWTARIWSDDIRESSIMWTKYHMSYLTDGCWSPT RPAVFYTTKMDGTLDIWDFIFKQNDPTLSLQVCDEALQSIRVQDGGRLIAAGSQSGTTTL LELSDGLCTLQRNEKALVTAMFDRETRREKILESRHREMKLKERTKSS------------ ------------------ALRKGVREVQKFVRKGEKGIVVLAGDTSPIDVICHMPVVCEE GELPYCYTPSKEDLGAACGSRRPTCMVMIKTHTVYDDLFKELKEELDTLPMPI------- --------------WKFLLTTDKHKNDATLKNNLMDAIKADDMAPFYEEVCAEFGWKVDQ NLLRKMKDANEEKLKEIDSAVEDAEKNLGETEVRDFMIKKGEYLCKIGDKDGMITQFRKT TEKTVALGYKLDLVFHQIRLGLFHMDHDLIKRNLEKAQSLIDEGGDWDRRNRLKVYRGVY MMSVRDFKTAAKLFLDTVATFTSYELMDYKTFVTYTVLCSMIALSRPDLRQKAIKGSEIL EVLHNSPCIKKFLFSLYNCHYGDFFISLAEVEQLMKYDRYLAPHYKYYTREMRIHAYSQL LESYRSLTLDYMAKAFGVTIQFIDQELSRFIAAGRLHCKIDKVGGIVETNRPDSKNYQYQ ETIKKGDILLNRIQKLSRVINIQRGLKNSSPAARGIPFNKISIGVPKETFPNECRVALAP ATVAALKKGITVNMEENSGLAAKFNNDDYAAAGANIAKNDVFDSDVIFKVRAPSMEEVPL FRDRGTLFSFLYPAQNQELVDAMAKKNMNLFAMDCVPRISRAQVYDALSSMANISGYKSV ILAANHFGRFFTGQITAXGKVPPAKVLVIGGGVAGLACVGTARNMGAITRCFDTRAAVGE QVRSMGGEFLEVSIEESGEGAGGYGKEMSKEFIEAEMALFARQAKEVDIIISTALIPGKK APILITKEMIDSMRPGSVVVDLAAESGGNIETTKPNEIYVYNDVTHIGLTDIPSRLPTQS STLYANNISKLFLSFGYFLDFEDEVSRGSCILHEGKKMWPPPPVKEPNYFADTLKDSLLY TTGLGSILGLGMASPNSAFATMVTVFGLSGIVGYHTVWGVKPALHSPLMSVTNAISGITA VGGLILMGGGYYPTDTIQTLAATAAFISSINIGGGFLVTKRMLDMFRRPDDPPEHNYLYA IPPAAFLAGYAACCQGEYPDIHQMTYLAASLCCVGALTGLSNQSTSRVGNTLGMIGVSSG IAATIGLLKPAPEVAVQMAACMGTGGTIGMVAAKKIEVTDLPQMVALFHSLVGAAAVVTC ISNYMAEFPHFATDPAANVTKTALFLGTYIGGVTFTGSLVAFGKLQGLLKSEPLMLPGRH MMNLGLLLANVGAIGWFMIDKNNTGLSLLGATSSLSAVMGVTLTMAIGGADMPVVITVLN SYSGWALCAEGFMLNNNLMTIVGALIGSSGAILSYIMCKAMNRSLPNVILGGYGTSSTGT GKAMEITGTHTEVNADQTLEMLIEANNIMIVPGYGLCVAKAQYPIAEMADLLRKKGKNVR FGIHPVAGRMPGQLNVLLAEAGVPYDIVHEMEEINDDMPEVDLTLVIGANDTVNSAAEED PNSIIAGMPVIRVWLSKQVIVMKRTLGVGYAAVDNPIFFKENSGMLLGDAKKTCDSLLAK TKMARPETIPGCPPGLEYLTQIDQLLVHQQVEIFEAFTNWETKNKYQIKNSIGQQIYFAA EESDGCMRQCCGPARGFTMHVTDNSGQEVIRVTRPFKCCSGINCCAFCAMEVEIEAPVGQ TAGYVKQSCLSPKYEIQDAVLKIEGPACICQGPCCTGDQEFIVKSQDVGKISKQWSGFVK EYFTKADNFGVSFPMDLDVKMKAVMVGAVFLIDFMFFEQQQNKVDEEMQQFMMMESQKAQ FQNQVHKLTDLCWDRCMDKPRDKLDYKTETCMSNCTERFIDVSLAITSRFQQMLQRQLMN RPEGLVQRRNVAQEVEDHDSKETRLTLMEEVLLLGLKDREGYTSFWNDCISSGLRGCILI ELALRGRVELEKTGMRRRSLLNRKIICKSDAPTGDVLLDEALKHVKETEPPESTQSWIEY LSGETWNPLKLKYQLRNVRERLAKNLVEKGVCTTEKQNFLLFDMTTHPLVESNVKQKLVK RVQESVLHRWVNDPQRMDRRMLSLLYLAHASDVLENAFAPLSDDDYEVAMKRVRELLDLD FEQESMKDGANELMWGVITAFSKGKKITAATEENCEVCVKFLTKFIASLDKIEKAFRKMC KTAKKDDNRFCYFIGGLEESATGILSEMSKPVSWGVPADKVCFKLFKKDEQICDIRYDKT FDFATLDLKKLKVKDLKNILSDWNEKCKGCTEKSDYVKLVEEKMVKHEPEA----ILNGF KLNWMNLRDADSGKVLWQSSDDLSQPEVEHEARVPKKILKCRAVAREINFSSKETMEKFR LEQRVLFKGKCLEEWYFEFGFVIPDSTNTWQSIIEAAPESQMMPANVLNGNVIIETKFFD GDLMVSTSKVRVFYVMPKVVSRSVVCTDTKDQEEYQGEKPLYVYYCLCGQMSLILDCPVE KLPMRRRDGARVIDSNKHAHKLTAEPDEIVHIKRPEGIEKQYRQKCKKCGLLLYYRHQNI ITFIVDGALKKEAE---KTYSSISAPQKVMVKKHTKNMGKFSSVTVSTVDEEDDEIEAKE IADSYAANARVINKQLLRKGFSKRKLLEEAELEAKRMRPKGTLIN--------------- ------------------------------------------------------------ VSSGSITINDDSSVQILAEEAVSMEDIDSAAVRDGLAKAHQELSTEEAKAQAQIALECYE ALQQSV-CKFFTTELGQRLEKSGKSKEMIETGHGLEKKKRFAYHTSELRLTEALHEPHIC ENILNYNVHAERKGSNRYAKGMSETFETLHGLVDKGVKVELGIPHELWDKPSAEVTKMHR ACFPLAESMEEDIEDWYYNHQKNLINYVCRERVLKNKD--FSPTDVTSEADVVKAILANS KFGKIDAAVNCAGIGIAVLTYNKNKDRVHDQQSFIKVLNVNAGGTFNVIRLVGQAMAKNE PNGDGERG-----XSVAAYDGQRGQAAYSASKGAIVGMTLPIARDFSNIGIRVNTIAPGL FDTPLLASLPEKVRSFLASTVPFPAKLGLPEEYAHLVQCLIENPMMNGECIRIDGALRAR HFHFRVNGRNSNAKQQLSRDYPVVDHEYDALVVGAGGAGLRAAFGLSNQGFKTACITKLF PTRSHTVAAQGGINAALGNVEEDKWEYHFYDTVKGSDWLGDQDSIQYMCEEAPKAVIELE NYGMPFSRLENGKIYQRAFGGQSLDYGQGGQAHRACCVADRTGHSMLHTLYGRSLYYDTD YFIEYFAVDLIMENGACKGVTAICLEDGTIHRFKANNTVLATGGYGRAYFSCTGAHTCTG DGTAMTTRAGLANEDMEFVQFHPTGIYGAGCLITEGCRGEGGYLINSEGERFMERYAPTA KDLASRDVVSRASTIEVREGRGVGPEKDHVFLQLSHLPPEQLHARLPGISETAQIFAGVD VTRDPVPVIPTVHYNMGGVPTNFRGQVIEYNGKDVLVPGLYAAGEAACVSVHGANRLGAN SLLDLVVFGRSCANAIAETHKPGDAAPSISPNAGEESVSLIDRYRYAKGNTLTSDLRIKM QKLMQNYAAVFRDGSTLKEGCDQLDALYTEMDIKVVDRGMVWNTDLVETIELENLMLNAL QTIHSAEARKESRGAHSREDCHERLDEYDYSKPLEGQQKKPFEQHWRKHTMCTTNRETGK TDLEYRPVVDKVLDSSKIQTIPPKIRAYMTALSQEDIISNTKTVVQGLDTLKNEHHQILN SLLSSLKTIKQGDTNLVEEKTNILKKSLETIELGLGESQVMMALTNHLQHVEAEKQKLRA QVRRLCQENAWLRDELANTQQRLQQSEQRVATLEEEKKHLEFMNEMKKYDGDNQLGFPED DDDQNPSAMXGCQRRG----ARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHD HPDVATMLNILALVYRDQGKYKEAANLLNDALGIREKTLGPDHPAVAATLNNLAVLYGKR GKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEQYYQRALEIYE TKLGPDDPNVAKTKNNLASAYLKQGKYKQ------------------------------- ----------LTQEIQAKKMKLRVNTQNAPFKQMENITNFIKFCEAMGMDKAGTFQTVDL YEGRNMAQVINCFQALGTECQRHGFDGPVIGSKPVEKNIREFSDEQMRAGQLQAGTNKCA SQGGGGQRHAADIRVQDMDRAGQSVLSGQMGTGGDSQAGMSSGGPRHAADIRADDFDRKG ADVIGLQAGSNKGASQAGMSMGGARHAADIRADDMDKAGQSVLSGQMG------------ ------------------------------------------------------------ ----------------------------------------------------------MT ESHSFGVLPITCHAWNSDRTQLALPNNHEVQIYRQKWSKVETLDEHAQRVTGIDWAPKSN LLVTCSADRNAYVWPALVILRINRAATCVKWSPLENKFAVGSGARLISICYFEQENDWWV SKHIKKPIRSTVTCIDWHPNNALLAAGSTDFKSRVFSGYIKEVDSKPEATAWGKKMTFST LMAEFSNGGGWVHSISFSASGDRLAWVGHDSSVSVVEAFEKTHFLPFVACTWVSEVDLIV AGHDCCPMHFSYNNGKLSFVKKMEEGKFSAKAHFRNLDSRGQSLATSHQNTISWLSIYNG DKQRAGKFATTGTDGQLIIWAMKKEIEGYVGFANLPNQVYRKSVKKGFEFTLMVVGESGL GKSTLINSMFLTDMYSAEHPGPSHRIKKTVQVDQQQVMLKEGGVQLRLTVVDTPGFGDAV DNSNCWSPVIDYIESKCDEYLNAESRVNRKSMPDNRVHCCLYFISPNGHGLKPLDVEFMK RLHDKVNIIPLIAKADTLTPDECREFKKTILNEIAQHKIRIYEFDDEEENKALKRLKDRV PYAVIGANTVVESGGKKVRGRVYPWGIVEVENLEHNDFIALRNMLIRTHMQDLKDVTNNV HYENFRYNKLASVSKSPLLQMEEEKKDHVQKMKKMEAEMEQVFEMKVKEKRQKLKDSETD LQRRAEQMKKSLEQQEKDLENQRRQF------------MARRYDTRTTIFSPEGRLYQVE YAMEAIGHAGTCLGILTKEGVILAAERRNTNKLLDEVSHSEKIYKLYEDMACSVAGITSD ANVLTNQLRLIAQRYILQYQEPIPCEQVVTTLCDVKQAYTQFGGKRPFGVSLLYMGWDRH YGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQEYKE-DKDLQAGLELVIKVLSKTLD TNKLTNDKVEIATLTRENGKTIIRIMSNEEVDVFIKKHEDEEAKAEAEKKKEMNEAWENL KQLTLRRQERLFGAHEIQHFNRDADETITWIMEKDTMLSTDDYGRDLASVQQLQRKHETL ERDLGALEEKVKSIGSEADRLTETHPEQADEIRRKQAEIEAIWERLKQKAIERRQRLDDS YYLHRFLSDYRDLVSWIHDMKTIISADELAKDVAGAEALLERHQEHKGEIDAREDSFRAT AEAGQKLLESDHYAVEEVKEKLVTLANEKTSLLELWEERRILYEQCMDLQLFYRDTEQAD AWMSKQEAFLANEDLGESLDSVEALVKKHEDFEKSLAAQEEKIKALDEFASKLIENEHYA ADDVAARRDALLQRRNALYQRANFRRSRLEEFYKYQMFERDADETKIWINEKLKAASDEG YLDPTNLQGKVQKHQNFEAELSANQARIDSVNTTGKELIDADHFNKDQIQERLDEIMQMW QQLVEQSEKKGNKLKEASEQQTYNRNVEDFEVWVSEIEGQLMSEDYGKDLTSVQNLQKKQ GLMESDVNSRQDRMEQIVKAANQFTESGHFDVENIQKKQVTLVERYRNLHDPMKSRQHKL SDAVKLQQFFRDVEDEDDWIREKEPIVASTNRGRDLIGVQNLMKKHQALQAELAGHDSRI QTVTQMGAEMIGNGHFASNDIQQKIDGLDDRWNQLKEKSGQRSQDLEDSLQAQQYFADAN EAESWMREKEPIVGNTDYGKGEDSAEALLKKHEALMSDLEAYRPVIDGLQEQAQACKQQE APVIDDIGKECVVALYDYQEKSPREVSMKKGDVLTLLNSSNKDWWKVEVNDRQGFVPAAY VKKIDSSLTASQSNLADEFTISVRQQQINTQYENLLQLGRQRKDKLEESCKAYQLVREAG ELSLWIADKETVALSDEVGDDLEQVEVVQRKFDDFQKDLKANEARLVELNTIAERLTAMG QTEAAEKIRIQIEDLNQRWAALQQVTQERAQNLGSAHEVQRYHRDADETKDWVEEKELTL GSTDYGHDLTTVQRLQRKHEGLERDLAALGDKVKELDETAQRLMQTHPDQAQSIYEHQKE INERWNSLTTQADQRKAKLLDSYDFQRFLSDFRDLMSWINSMMALVSSDELAKDVTGAEA LLERHQEHRLEIDARAGTFQAFEMFGHQLLQNDHYASDDVKDKLKDLADSREQLEQAWIA RRAKLDQCLELQLFNRDCEQAETWMAAREASLADSVDGSEGVESLLKKHEDFDRAITSQE EKIKALEAFADQLKAGDHYDKQGIDDRRDEVLERWRKLKDNLLENRENLGKVQSLQQFSR DVDEMEIWIQEKLQTAMDESYKDPSNIQAKHQKHQAFEAELAANSDRIGSVLKMGDKLIE SKQCSGSEDAVQARISKLLEEWEYLTTRSSEKSGKLKEANHQRQYTAAVKDLEFWLGEVE HMLEVEDYGKDLATVQNLVKKHQLLEADVKAHDDRIKDLNEQADAFIESGMWDTESIKEK KQTISERYERVVTLTTHRMARLEEANRLHQFLRDIDDEEAWIKEKKLLVGSDDYGRDLTG VQNLRKKHKRLEAELSSHEPAIQTVQDMGEKILSESNLMNEEIQTRLEQLNTSWDDLNNM AGNRGQKLDQSLAYQQFAASIEEEEAWIAEKQHLLSGDDFGDTLAAVQGLLKKHDAFETD CQVRQNRCTEIKKEGDKLIAEGNHNADSVEKRCLELQEKLESLHSSAQLRKTRLIDNSAF LQFIWKTDVVESWIADKENQVQSEDYGRDLSSVQTLLTKQETFDAGLQAFEKEGIQTITA LKDQLVTSNHAQTPAIEKRYADVISRWQSLLANSDARKQRLLRLQEQYRQVEDLYLTFAK KASAFNSWFENAEEDLTDPVRCNSVEEIKALREAHDQFKASLSAAEADFNQLAQLDKQIK SFNVGPNPYTWFTMEALEDTWRNLQKIIKERDDELAREQQRQEDNDVLRKQFAQAANAFH GWLTDTRAAMMEGTGTLESQLEATKRKSAEVRAQRSQLKRIEDLSAAMEERLILDNRYTE HSTVGLAQQWDQLDQLGMRMQHNLEQQIQACNQSGVSEDALREFSMMFKHFDKDKSGRLN QQEFKSCLRALGYDLPMVEEGQRDPEFEAILDVVDPNRDGHVSLQEYMAFMISRETENVQ SAQDVEAAFRALTAGERAYITGSELYSNLTKEQADYCISRMRPYVDPSGRSVTDAYDYVD FTTALFINAIQCYQCDSNEGKSCPATRPFDINLNALIDCNSFEATVPGTFCMKITQESPG WRGWKKVTRRCGSRSDTGVAWGCRWTYAENGVWREVCYCEDRDGCNGSSHIDKDDLDNPQ LVSEYVNDIYEYMRELERLDVNGRMRGILIDWLVQVHLRFHLLQETLYLTVGIIDRFLML EVSRSKLQLVGVTSMLLASKYEEMYAPEIADFVYITDNAYTKSDIRKMECIILKTLDFNL GRPLPLHFLRRNSKAGEVDANKHTLAKYLMELTIVDYEMVHHYPSQIAAAALGLSMKLMD WSDTLHYYSKYTERELMPIMKKMALLVTKKLAAIKTKYQSSKFMRISTIPELKSDCITEL AARGRTRGRRQNNPSPGPESDLERVFIWDLDETIIIFHSLLTGSYAQRYGKDPPGSVSLG LRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSNYNFATDGFHAAATNNLCL ATGVRGGVDWMRKLAFRYRRIKEIYNSYRNNVGGLLGPQKREQWLQLRSEIEQLTDNWLT LALKSLTITNSRSSCVNVLVTTTQLVPALAKVLLYGLGGVFNIENVYSATKIGKESCFER IVSRYGRKCTYVVVGDGRDEEAASKQMNWPFWRISNHSDLAALHHALDLGYL-TALSVGG HRTTGQSVRTQNVMAASSIANIVKSSLGPVGLDKMLVDDVGDVTITNDGATILKLLEVEH PAAKVLVELAQLQDEEVGDGTTSVVIIAAELLKNADELVKCKIHPTSIISGFRLACKEAC KYIQEHLVISTDELGRECIVNAAKTSMSSKIIGPDSDFFSNMVVEAAYAVKTSDGKGGHR YPVKAVNVLKAHGKSSRESVLVHGYALNCTVASQMMLKKIPNAKIACLDFSLQKAKMKMG VQVLIEDPTKLDAMREREFGITQERIQKILASGANVILTTGGIDDLCLKYFVEAGAMAVR RCKKQDLKRIAKATGGQFVSTLANMEGDETFDASMLGGAEEVVQDKICDDELILIKGPKA RTCASIILRGANDYMVDEMERSVHDALCVVKRVLESKSLVPGGGAVEAALSIYLENFATS LSSREQLAIAEFAKSLLVIPKQLAVNAAEDSTDLVAKLRAYHNKSQTSPEHKELKWVGLD LYEGTVRDNKKAGVFEPAISKIKSLKFATEAAITILRIDDLIKLNPEDKQGPSYQDALRQ GMLDDESARLLASKTLLNDMLVEGKDLTVEYNIFNIGGSAALNVELSDASFPSADFEIVR GNLNVMWPRIAPGSNVSHAVVLRPLKSGYFNFTSAEITYLPFEEEKLFGYTSAPGEGGII NFR----------------------------------------------NSGSHKDRTDK YRSILNQIDGLKAFVEALVNENVSLVISRQILTEFCQHLPSLPDAAARTVSHFTLEKVQP RVISFEEQVASIRQHLATIYERETDWREAANVLVGIPLETAQKQYSNDYKLETYLKIARL YLEDEDPVQAEAYINRASLLQAESKNEQLQIYYKVCYARVLDYRRKFIEAAQRYNELSYK TIVAEAERMTALRNALIGTILASAGQQRSRMLATLFKDERCQQLPAYAILEKMYLDRIIR SSELIEFAELLQTHQKALTSDGSTILDRAVIEHNLLSASKLYNNITFEELGSLLAIPPLK AEKIASQMITEGRMNGYIDQIDAIVHFESREALPNWDKQIQGLCFQVNNIIEKMGQVSPE WTSKAVEQQLTMKLTDTVVRNFRVAKVFRENNDRINSVDFATNGETLISSSEDDSIVIYD CQNGTPKRTLNSKKYGVDLIHYTHATNTAIHSSTKVDDTIRYLSLHDNKYIRYFQGHTKK VVTLCMSPIDDTFLSGSLDKTIRLWDLKSPNCQGLMHLPGRPVAAFDPEGLIFAAGINSE SLKLYDLRSFDKGPFATFKLQQDKDCDWTGLKFSPDGKLILISTNGQVIRLIDAFQGTPL QTFMGHQNHKGIPLEASFSPDSQFVFSGSTDGKIHAWNTETGAKVVVLNGDHTGPVQCVQ FNPKYMMLSTACNNMAFWLPQVDEEHIKVEKVGEKKNVGMITLNRPKALNALFSPLMSEM SQALDEFDNDPEIGCLVLTGSERAFAAGADIKEMLPKTFKDVYKGNFLNNWNRLQFNKKP IIAAVNGFALGGGCEIAMMCDIIYAGEKAQFGQPEISLGTIPGAGGTQRLTKAIGKSKAM EMVLTGDRITAQEAEKAGLVSKVLPPDQLVSEAIKTAEKIANHSQIIIQMAKESVNASFE MTLAEGLHFEKRFFHQSFATHDRAEGMAAFVEKRKADFKD >Ophelina_sp XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXX--TQFRQFQTSAVQRDIDQAAKYIGAGAATV GVAGAGAGIGSVFGSLVIGYARNPSLKQQLFSYTILGFALSEAMGLFCLMMAFLILFAFM AHYKESGKAPEATIHRIRITLTSRNVKSLEKVCADLIKGAKEKNLKVKGPVRMPTKILRI TTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XMATQISKKRKFVADGVFKAELNEFFTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVL GEKGRRIRELTSVVQKRFNFPEGTVELYAEKVTTRGLCAIAQAESLRYKLIGGLAVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGEPTHDYVDTAVRHVLLRQ GVLGIKVKIMLPWDPTGKIGPKRPLPDHVSIVEPKDEQAPAQPYSEHKGGK------GGS AGGKFRISLALPVGAVVNCADNTGAKNLYVIAVQGIKGRLNRLPAAGSGDMVAATVKKGK PELRKXVMPAVIIRQRKSIRRKNGLFIYFEDNAGVIVNNKGEMKGSAITGPVSKECADLW PRIASNAGSI-------------------------------------------------- -----KADRDEASPYAAMLAAQDVAEKCKSLKITALHIKLRATGGNKTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRLVGKPRGLRTARKQRTHRRDQRWHDKD YKKSHLGTRWKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP KDGCLNYIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALFKEKKERPRS--- ------------------------HPGRATVPKTEVREKLARMYKTTPDVVFAFGFRTQF GGGKTTGFALIYDSLDLAKKFEPKYRLVRHGARKQRKERKNRQKKVRGTKKAKVGA---- -LVSRKTYTTPRRPFEKERLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDE KDSKRLFEGNALLRRLVRIGVLDESKMKLDYVLGLRLEDFLERRLQTQVFKLGLAKSIHH ARVLIRQRHIRVR--------YVVRLDSQKHIDFSLKSSYGGGRPGRVKRKNMKKGAGGG GD-----------------------------------------VVTTIPTIGFNVETVEY KNISFTTWDVEGRDKIRPLYRHYYMNTQAFIFVVDSNDLERLEDAEEELSRAMSEDELRE IPLLVYLNKQDLPNAMSVAKATESLKLHSMRNRKWYIQPCCATTGQGLYEGLDWIADMIR NR----------------------KRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRRKQHMVRMNVLADALRSICNAEKRGKRQVLIRPCSKV IVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVALRDMEKWTTNL LPSRQFGFLVLTTSGGIMDHEEARRKHLGGKILGFFF--RMHAP-EGISQSALPYRRSLP NWLKLTSDDVKEQIFKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKAKGLAPD IPEDLYHLIKKAVNIRKHLERNRKDKDSKFRLILVESRIHRLARYYKDKKVLPPNWKYES STASTLVAVAEPPEIKLFGKWSTEDVQVSDISLTDYIAVKEKYAKYLPHSSGRYQVKRFR KAQCPIVERLTSSLMMHGRNNGKKIMAMRIVKHAFEIIHLLTGENPLQVVVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAMWLLCTGAREAAFRNIKSIAECLADELINAAK GSSNSHAIKKKDELERVAKSN---------------------------------SASRDK KLILWRLTRDQRYGYPQKALHGHGHFVSDVVLSSDGQFALSGSWDSTLRLWDLSTGQTTR RFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIEDGHSDWVSCVRFSPNT QNPIMVSCGWDKIVKVWNLTNCKLKTNHFGHNGFLNCVTVSPDGSLCASGGKDGSAMLWD LNEGKHLYTLDGGDTINSLCFSPNRYWLCAATGPSIKIWDLEGKIVVDELRQEVISSSGK APECISLAWSADGQTLFAGYTDNLIRVWQVSMAARMREYKLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKVVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVRKPPEQWNCAI-------- --------------------------------INLKVTGQDGSVVHFKIKKNTPLRKLMS AYCERTGVKMGSMRFRFDGQPINETDTPSQLEMEDGDAIDVFQQ------ALPLNPKPFL NGLTGKPVMVKLKWGMEYKGYLVSVDGYMNLQLANTEEYIDGCLSGNLGEVLIRCNNVLY VRGVEEEEEDGEMKD-------------------------------------LARGLHEC AKALDKRQXHLCILANNCDEPMYVKLVEALCAEHGINLIKSHSNKK-------------- ----------------------------------MAAIRKKLVIVGDGACGKTCLLIVFS KDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSI DSPDSLENIPEKWTPEVRHFCPNVPIILVGNKKDLRNDQNTIRELAKMKQETVKAEEGRS MADKIGAFAYLECSAKTKEGVREVFETATRAALQVKKKKGRKXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------- ----------------------------------------PQLKAYQKIQARLVRELEKK FSGKHVVFIAQRRILPKPTRKTRRKNKQKRPRSRTLTAVQDSILDDLCYPAEIVGKRIRI KLDGSRLVKVHLDKNQQTNIEHKLDTFTAVYKKLTGKDVNFEFPEYVLGRGGFRGGFGGR GRGRGRGRGRGKDGDKEWMPMTKLGRLVKDMKIKSLEEIYLFSLPIKEFEIIDFFLGSAL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDFNGHVGLGVKCSKEVATAIRGAIILAKLSV VPVRRGYWGNKIGKPHTVPCKVTGKCGSVLVRLIPAPRGTGIVSAPVPKKLLSMAGIDDC YTSARGQTATLGNFAKATYAAIANTYSYLTPDLWKETVFTKSPYQEFTDYLAK-----DA LALKEDDVSKFLVAGTHLGSSNVDFQMEQYVYKRRQDGTYIINLRRTWEKVLLAARAIAA IENPADVCVISARPYGQRAVLKFASYVGATPIAGRYTPGTFTNQIQAAFREPRLLVVTDP RIDHQPVTEASYVNIPVIALCNTDSPLRYVDIGIPCNNKSRESVGLMWWMLAREVLRLRG TISREVPWEVMTDLFFYRDPEEVEKEPGVTDWAQESIVAPVPIPTEEWSATNTGDWAAPP TGGEWGG--FNKMVSSSRRKNRKRHFNAPSHIRRKIMSAPLSKELRQKYNARSLPIRKDD EVQVVRGHYKGQQVGKVVQVYRKKFVVHIERIQREKANGASVHVGIHPSKVVLVKLKMDK DRKSILERKARSRTQGKHTEESI------------------------------------- IKVGPVPVLVMSLLFIASVFMLHIWGKYTRG---------------REYTINIHKRIHGI GFKKRAPRAVKEVRKFAVKQMGTPDVRIDTRLNKHLWSKGVRNVPYRVRVRLARKRNEDE DSPHKLYTLVTYVP---------------------------------------------- ------------------------------------------------------------ ---------------------MIGRIEYVHNKNLHSQGYKXDNFLMGIGRHCNKXFLIDX GLAKKYRRPIEQDSTAYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRGS LPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGHPAEFAMYLNYCRGLRFEEAPDYMYLR QLFRILFRTLNHQYDYVFDWTILKQKAATSMNPEKLKQRIGGKGTARRKRKVVHRTATTD DKKLQSSLKKLAVNNIPGIEEVNMIKEDGQVIHFNNPKVQASLAANTFAVTGHAENKQIT EMLPGILNQLGAESLSNLKKLATATEDIDEEDDEVPDLVENFDEASKAEMTRYSLDPENA TKSAKAMGSHLRVHFKNTRETAQAIKRMHLRRAVRYLKNVTDKRECVPFRRYNGGVGRCA QAKNHGATQGRWPKKSAEFLLQLLKNAESNAEYKGLDTDHLVIEHIQVNRAPKMRRRTYR AHGRINPYMSSPCHIEVILAEREQAIARPKKKKVSQKKLKRQKMMQRD-------ELSDE QKQEIKEAFELFDTDKDQEIDYHELKVAMRALGFDVRKADVLKVLKDYDREGTGKISFDD FNEVMTDKILERDPMEEMIKAFKLFDDDDSGKISMRNLRRVARELGEDMTEEELRAFDKD NDGEINTEEFIAIM-------GISRDKWHKRRKTGGRQNPLRKKRKFELGRPAAHTRIGA HRVHTVRTRGGNKKYRALRLDTGNFAWGSEAQTRKTRIIDVVYNASNNELVRTKTLVKNC IVVIDGTPFRQWYEAHYATPLGRKKGAKLSEEE-------------KYDERKKTAKVEHS LEDQFATGRLLACISSRPGQCGRCDGYILEGKELEFYQRKIKAKKGK------EKFQHIL RVMNTNIDGRRKVPFAVTAIKGVGRRYSHVVCKKADVDPTKRAGELSEEDVEKIVTIMSN PRQYKIPDWFLNRQKDIKDGKYSQVMSNILDSKIREDLERLKKIRAHRGLRHYWGLRVRG QHTKTTGRRGRTVGVSKKKCSGTESDSDDSVPDLEEMAAAAGLPEELVSKAKQSRSEKKA RKAISKLGLKQVGGVTRVTIRKSKNILFVINRPDVYKSPASDTYIVFGEAKIEDLSQQAQ MAAAEKFKAEEEVDEAGIEAKDIELVMSQANVSRGKAVKALRNNQNDIVNAIMMGRVRTK TVKKAARVIIEKYYTRLTLDFHSNKRICEEIAIIPSKKLRNKVAGFVTHLMKRIQKGPVR GISIKLQEEERERRDNYVPETSAIEEVDPDTKEMLKMLELANIPGLQEKQPIESAMRWEY KEEHPFEKRRAEGEKIRKKYPDRVPVIVEKSPKARVGDLDKKKYLVPSDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGALYQEHHEEDFFLYIAYSDESVYGMRELRISKL CLNICVGESGDRLTRAAKVLEQLTGQSPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAE EILERGLKVREYELRKNNFSETGNFGFGIQEHIDLGIKYDPSIGIYGMDFYVVLNRPGHN ISKRRRCKSKVGFAHRVTKDESMKWFQQKYDGVILPGK---------------------- ------------------------------------------------------------ ------LSVQLLARCKSIEVGDTLKTRASSNGAQKLFGMVITVGQAIVYVMTGMYGDPAD IGAGVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVN TGRGTEFEGAVIALFHLLATRTDKVRGLREAFYRQNLPNLMNLLATVLVFGIVIYFQGFR VDLPXKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNSLLV------------------ -------------------CYYLSPPETLSHVAEDPIHALLYIVFMLGSCAFFSKTWIEV SGSSAKDVAKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFMGAIG SGTGILLAVTIIYQYFEIFVKEQSEMGGMGTLLFQSERAFQKQPTVFLNKKSRLLPRYVK SVGLGFKTPREAIDGNYIDKKCPFTGNVSIRGRILTGVVQKMKMQRTIVIRRDYLHYVRK YNRFEKRHKNMSVHMSPCFRDVQAGDIVTVGECRPLSKTVRFNVVKVTKGSGSKKGFSKF MVNVPKQRRTYCKGKNCRKHTVHKVTQYKKGRDSLYAQGKRRYDRKQSGYGGQTKPIFHK KAKTTKKIVLRMECSSCKYRKQLAIKRCKHFELGGDKKKKGQMIQFMGRVIRSQRKGAGS VFKAHTKNRKGAARLRAVDYAERHGYIKGVIKDIIHDPGRGAPLAKVMFRDPYKYKMRTE TFVAAEGMYTGQFVYCGKRANLQVGNILPVGSMPEGTIVCCLEEKTGDRGRIAKASGNYA TVISHNPDTRRTRLKLPSGCKKVVPSTNRAMVGIVAGGGRIDKPMLKAGRAYHKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGKASTVRRDTSAGRKVGLIAARRTGRLRGSKQ--- -XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------RYCKNKPYPKSRFCRGVPDA KIRIFDLGRKKARVDDFPLSVHLVSDEYEQISSEALEAARICANKYLVKNCGKDAFHLRV RVHPFHVLRINKMLSCAGADRLQTGMRGAFGKPQGTVARVNIGQVLLSVRARDQHKEKVV EALRRAKFKFPGRQKIFVSNKWGFTKWNREDYAVMRQDGRLVPDGVNVQYKPHRGPLQAW MDAQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMVDDRAAAKELDQWVDQLMECKQLTENQVK TLCEKAKEILAKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGRSPDTNYLFMGDYVDR GYYSVETVTLLVALKVRYKDRITILRGNHESRQXTQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHSNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRC GNQAAVMELDDALKYSFLQFDPAPRRGEPHVTRRTPDYFLXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXGIAIGRLSEERKXWRKDHPFGFVARPTKNPDGTLNLMNWECAIPGPKKTPWEGGLY KLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSLLDEEKDWRPAVTIKQILLGIQE LLN--------------------------------------------------------- -------------------------------------------------------SMTVE GPPPAEEGIARVPLPHGVGGPGIGRAMGRGIGAGGGLQGPVRGVGGPSQQHMTPQPQMMR G----EIPSFKLVLVGDGGVGKTTFVKRHLTGEFEKKYIATLGVEVHPLVFHTNRGPIRF NVWDTAGQEKFGGLRDGYYIQGQCAIIMFDVTARITYKNVPNWHRDLVRVCENIPI---- -----------------------------------------------------------A LEPPEIEMDPSMAAKYEAELRDAQQTALPDEDEDL------------------------- ------------------------------------------------------------ ---------------------------------------------------GLDKQIKEI KEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLVRAVAHHTECTFIRVSGSELVQ KFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRLESGSGGDSEVQRTMLELLNQLD GFEPKQNIKVIMATNRIDILDSALLRPGRIDRKIEFPAPNEEARLDILRIHSRKMNLTRG INLRMIAEMMPGASGAEVKGVCTEAGMYALRERRV------------------------- --------------------LSKTAAAPIERVKLLVQNQDEMIKAGRLDKPYKGVIDCTT RTFQTEGLLPFWRGNLANCIRYFPTQALNFAFKDQIKAMFKMSKTDSYAVKFSKNIASGG AAGAMSLCFVYSLDYARTRLANDAKAGKKRQFNGLVDVYKKTLKSDGFVGLYRGFVISCV GIIIYRGCYFGFYDTLKPIVLGEGASLWTSFILGYIVTISSGLVSYPVDTIRRRMMMTSG EAVKYKGSMDCAVQVIKNEGFMSLMKGAGANILRGVAGAGVLSGFDKFKEVYVAWRL--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------LWSDPEDTQGWGVSPRGAGYLFGSDVVQQFNAANDVDLICRAHQLVME GYKWHFNDTVLTVWSAPNYCYRCGNVAAILELDEHLQREFTIFEAAPQEQRGKPQADYFL -RLPPEVNRILYIKNLPYKITAEEMYDIFGKYGAIRQIRVGNTPETRGTAFVIYEDIFDA KNACDHLSGFNVCNRYLVVLYYQPNKAYKKMDLQKQAEDLEKMKQAHGLSTPDLKMSIGV PIKVLHEAEGHVVTCETNTGEVYRGKLIEAEDNMNCQMSNLTVTYRDGRVAQLENVYIRG SKIRFMILPDMLK------------------------------------MQNEAGEYVDM YIPRKCSASNRIISAKDHASIQINIAAVDETTGRMTGQYKTYAICGPIRRMGESDDCINR LAKKDSIISKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------- ------------------------------------------------------------ -----------------------------------------------NIVIMLVGNKSDL RHLRAVPTDEAKAFAEKNNLSFIETSALDSTNVETAFQNILTEIYKIVSQKQIRDSPDDN NVQTIHVAPTDTTADRKQQKCC-------------------------------------- ------------------------------------------------------------ -------------FIAQLKQKYTQSNGRRPFGLSSLIIGFDGTPHLYQTDPSGTYHEWKA NAIGRSAKTVREFLEKHYTDD--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------SNSGGEREIQRTLLELLNQLDGFDSRGDVKVIMATNRIETLDPA LIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTLNKDVDLEDYIMAKDELSGADIKAICT EAGLLALRERRMKVTNEDFKKAKDNVLYRKNEGTPEGLYL-RKPYSPHRADSTLDYALAR TDDLVNWARKGSLWPLTFGLACCAVEMMHFAAPRYDMDRFGVVFRASPRQADCIIVAGTL TNKMAPALRKIYDQMPDPRWVISMGSCANGGGYYHYSYSVVRGCDRIIPVDIYVPGCPPT AEALLYGILQLQKKIKRMKTVQMWYRKSDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYA NNSNYKNDTMIRKEAYVHKSVMDELKRIIEDSEIMQEDDALWPPPDRVGRQELEIVIGDE HISFTTSKIGSLVDVNQSKDPEGLRTFYYLVQDLKCLVFSLIGLHFKIKPIMVAQKKSKK TIESINSRLALVMKSGKYVLGYKQTLKTLRQGKAKLVIIANNTPPLRKSEIEYYAMLAK- ------------------------------------------------------------ ----------------------RVDLVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGF LCVFAVNNGKSFEDINQYREQIKRVKDMDEVPMVLVGNKVDLPSRAVETKQGKQLAESFG IPYVETSAKTRQGVDDAFYTLVREIRKYMGDRYNIHSQLEHLQSKYIGTGHADTNKWEWL TNQHRDSYSSYLGHFDMLNYFSVVENEAKARVRFTLXEKMLQPCGPPLERP--MKVELCH FSGYKIYPGHGKRAIKVDGRAFMFLNAKCEKSHMMKRNPRKINWTVLYRRKHKKGLEEEK TKKRTRRTTKFQRAITGATLGDIMAKRNQKPEVRKAQREQAIRAAKEKQKAKDASRPRVG GKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------- ------------DELKTELSQLQVAKVTGGAASKLSKIRIVRKSIARVLTVINQTQKENL RKFYKPKDLRPKKTRAIRRALTKHELSLKSSKQLRKDRLYPMRKFAVKDKKKGPKVTDKV YFDIEIGGESAGRIVIGLFGKTVPKTVKNFKTLAEGTETYKGSKFHRVIKDFMIQGGDFT RGDGTGGKSIYFEDENFKLKHYGSGWLSMANAGKNTNGSQFFITTKKTEWLDGRHVVFGK VLEGMSVVRKIESTKTSRDKPEKDVVIADSGSIAVESPFAVAKEPSEEKKKKATLKYTVD CTHPVEDGILDCASFEKFLNDRIKVNGKTGNLKSKVAIESDVPFSKRYLKYLTKKYLKKN NLRDWLRVVANNKESYELRYFQINNEEDEEDDAD--------------CEGPDAMYVKLV SSDGHEFIVKRDHALTSGTIKAMLSGPGQFAENETNEINFREIPSHVLQKVCMYFTYKVR YTNSSTEIPEFPIAPEIALELLMAANFLDC-------ELAKHKDAKSLWLAIHDKVYDVT KFLEEHPGGEEVLLEQGGNYGTEAFEDVGHSTDARELMEQ-------------------- --------------MSYMLQHLNNGWQVDQAILSEEDRVVIIRFGHDWDPTCMVMDETLY RVAEKVKNFAVVYLVDISQVPDFNKMYELYDPCTVMFFYRNKHIMIDLGTGNNNKINWAM EDEQEFIDIVETVFRGARKGRGLVVSPKDYSTKYRYKKLQRQLEFLEVQEEYIKDEQKNL KKEYLHAQEEVKRIQSVPLVIGQFLEAVDXNTGIVGSTTGSNYYVRILSTIDRELLKPSA SVALHKHSNALVDVLPPEADSSITMLSADEKPDVQYSDIGGMDIQKQEVREAVELPLTHF ELYKQIGIDPPRGVLMFGPPGCXKTMLAKAVAHHTTASFIRVVGS--------------- --------------------------------------------------------VKVI MATNRADTLDPALLRPGRXDRKIEFPLPDRRQKRLIFSTITSKMNLSEDVDLEDYVARPD KISGADINAICQEAGMQAVRENRYVVLPKDFEKGYKNNIKKDETEHEL--GHQPLTLESI RERVLLVLRLYDKVDPEKLSVDSHFMNDLGLDSLDQVEVIMAMEDEFGFEIPDGDAEKLL RPADIVQYIADKEDI--------------------------------------------- ------------------------------------------------------------ ---------------------------------------------------DMIRRRNLR TRSIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVCLISATLPHEILEMTSKFMTDPI RILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYD------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GLSLVQTTDFFYPLVDDPYMMGKIACANVLSDLYALGVTECDNMLMLL AVSQKMSEKERDVVIPLMIRGFKDLAEEGGTSVNGGQTVVNPWVTIGGVATTVCQPNEFI MPDNAVVGDVLVLTKPLGTQVAVNAYQWLEQPDRWNRIKLVVSEDDVRKAYQRAMFSMAR LNRTAARLMHKYNAHGATDVTGFGLLGHANNLARIQKAEVGFVIHNLPIIAKMAAVSKAC GNMFGLLQGHSAETSGGLLMALPREQAAAFCKDIEXQEGYQAWIVGIVEKGNRSARIIDK PRVIEVPAKEKD------------------------------------------------ ------------------------------------------------------------ ----KLEEMINELSTAMTGVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMT LGQVYYLKRFFEVRRVVMAATLQPYLTAVRHTLQAAMCLENFASQVVERHNKPEVEVRSS KELLLTPVVISRNEKERVLIEGSVNSLRISIAVKQADEIEKILCHKFMRFMMMRAENFRV LRRKPVQGYDISFLITNFHTEQMYKHKLVDFIIFFMEEIDKEINEMKLAVNSRARTSAEE FLKQF------------------------------------------------------- ------------------------DCCVLVFDVTVGNTFKTLDSWRDEFLIQASPRDPEN FPFVVIGNKIDLENRAVSTKRAQQWCHSKGDIPYFETSAKEAINVEQAFQTVAKNALAQE TEVDLYS-------------------TAPFDARFPNQNQTRNCWQNFVDYHRCHKIDDYE PCEYFKKVYSSLCPNEWVSKWDEQIENSTFAGKI-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------VTMMQVEEKPDVTYSDVGGCKEQIEKLREVVEVPLLHPERFVNLGI EPPKGVLLFGPPGTGXTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMART KKACIIFFDEIDA----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------T REHALLAYTLGVKQMIIGVNKMDSTEPPYSEARFNEIKKEVTAYIKKIGYNPDAVPFVPI SGWHGDNMLKTGWFKGWTAESGTTLISALDNIEPPKRPTDKPLRLPLQDVYKIGGIGTVP VGRVETGVLKPGMVVTFAPAAITTEVKSVEMHHTALDEALPGDNVGFNVKNVSVKDIRRG NVCSDSKSDPAKESEEFKAQVIILNHPGQIQAGYAPVVDCHTSHIACKFRELLEKIDRRS GKKLEDNPQHVKSGDAAIVEMVPQKPMCVEAFSDYAPLGRFAVRDMRQTVAVGVIKSVKK RDGGQGKVTKAAQKA--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----TGQQTTSFTGHTGDVMSLSLSPDMRTFVSGACDASAKLWDIRDGMCKQTFSGHES DINAITFFPNGFAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRXLLG GYDDFNCNVXTXYKQDRAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKIWN-SYAYLF KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES FRSITRSYYRGAAGALLVYDITRRDXFNHLTTWLEDARQHSSSNMFIMLIGNKSDLEARR DVKKEEGEAFAREHGLIFMETSAKTAANVEEAFINTAKGIYQKIQDG------------- --------------------MTRGRTELGDITVHNIKQLKRLNQVVFPVTYNDKFYKDVL EVGELAKLAYFNDIVVGAVCCREDKTDGQRRLYIMTLGCLAPYRRLGIGTVMLEHVLKIC EIDGNYDNVFLHVQVNNDSA--FYEKFGFEIVERKQNYYKRIEPADAFVLQKTFRKXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- -----LGDQQHCDEAKANDLPHMDAEALKKLNKNKKLVKKLAKKYNAFLASDTLIKQIPR ILGPGLNKAGKFPTILSHSESMTGKVDEVKATIKFQMKKVLCLAVAVGNVAMTQEELCSN IQLAINFLVSLLKKNWQNVRALYIKSTMGPAQRVY------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------AIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKEVMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEF-------- ------------------------------------------------------------ ---MFKNTFQSGFLSVLYSIGGKPLEIWDKXVRNGHIKRITDNDIQSLVLELVGTNVSTT FITCPADPTKVLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPF ICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDEL PAEFKLYLPVANKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---YSFDG LIVFGLLFICTCAYMKRV-PKLLXCQKKGVLGVFYKAAVIGTRLHVPVALACVFMGLYVL FI---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------LYCIYVAIGQ KRSTVAQIVKRLTDADAMKYTIVVSATASDAAPLQYLAPYAGCAMGEYFRDNGKHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNEDFGGGSLTALPVIE TQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGAAAQQKAMKQVAG SMKLELAQYREVAAFAQFGSDLDAATQQLLNRGVRLTELLKQGQYVPMDVAEQVSVVYAG VKGHLDKVDPARITSFEAEFLAHIRASHQDILKSISEKGMIDEATDAKLKETVLNFLAGF MEAVFSIPFSVLECPNLKLKKPSWVKAPSSMVVFAIILASYFLVTGGIIYDTIVEPPSIG STTDERGNSKPVAFMPYRVNGQYIMEGLASSFLFTMGG---------------------- ------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEYAQVTKMLGNG RLEALCFDGAKRLCHIRGKLRKKVWINQSDIILIGLRDYQDNKADVILKYTPDEARNLKA YGELPESAKINDDMDDNITFDDIDEILVRFLMKLSHETVTIELKNGTQVHGTVTGVDVSM NTHLKAVKMTXKNKDTVQLDSLSIRGNNIRYYILPDSLPLDTLLIDDTPKAKAKKXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------ ----------------------------------------------SQPSKGPFHFRAPS KIFWRTCRGMLPHKLARGKEALDRLKVFEGIPPPYDKQKRLVVPSALKVLRMKPRRKFCV LGRLSHEVGWKYQNVVATLEAKRKVKSAHYWQKKKLENKYRVQAQKATTQQKVIAEYGF- --------------------------------------------GFSYTDANKNKGITWG KDTLWVYLENPKKYIPGTKMIFAGLKKKNERADLIAYLEESTK----------------- ----------------------------FYAEHYGKLFFPSLVAYMSSGPVIGLVLAREK AISYWRELIGPTNAIKARETHPDCLRAIYGTDDQRNGLHGSDSYSSAEREIRFFFPDSIV EPIPVGQAARDYLAKAVNPTLLK--------------------------------MFEAR LVQGSLLKKVLEAVKDLLNEATWDCNSTGMSLQAMDSSHVSLVSLMLRSDGFDTFRCDRN LSMGINLGSMSKILKCAANDDAITVKAGDNADNVTFMFESPNGEKVSDYEMKLMDLDTEH LGIPETDYSCVIKMPAAEFQRICRDLSQIGESVIICCTKEGVKFSATGDLGTGNIKLAQT ANVDKEEEAVIIEMQEAVTLTFALRYLNFFTKATPLSSQVSLSMSPEVPLVVEYKIGDMG YIRYYLAPKIEDGD--KSIAAYHTTERGAKGKIVAVIGAVVDVQFDEGLPPMLNALEVEN RSPRLILEVAQHLGENTVRTIAMDGTEGLIRGQVCQDTGSPIKIPVGPETLGRIINVIGE PIDERGPVNAKHFSAIHAEAPEFTEMSVEQEILETGIKVVDLLAPYAKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMMETGVINLKDDSSKVSLVYG QMNEPPGARARVALTGLTVAEFFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIA ELGIYPAVDPLDSSSRILDPNVVGEEHYTIARGVQKILQDYKSLQDIIAILGMDELSETD KLTVARARKIQRFLSQPFQMAEVFTGSVGKLVPLKDTIKGFKMILSGELDHLPEVAFYMV GPIEEVIQKAERLAEE-MLMPKKTRVQIYEHLFKEGVMVAKKDFHAPKHPELDLPNLHVI KALQSLKSRGLVTEQFAWRHYYWYLTNEGIQYLRDFLHLPPEIVPSTLKRQAGGEDRSQY RRGGPSDKKGDAGAGATMGQEQSQLSQQDIEKLKRDTRFTHGEIQDWYDKFHGDYPDGVI TKEGFIDMYSQMFPTTNAREFAEHVFRAYDTDGNGEIDFQEFLATLSVASRGSVDEKLEW AFSMYDIDGNGAVSREEAVQIITSIFKMRG----EPKPRDKAEETALELFLXLDKNKDDN LSKREF------------------------------------------------------ ------------------------------------------------------------ -------GDFGYCPRVYCENQPMLPIGLSDVPGETMVKLYCPKCQDVYTPKSSRHHHTDG AYFGTGFPHMLFMVHPEYRPKRPANQFSPRLYGFKIHPLAYDLQYQAAXKFKSGYGNSKR -----------------------------YMVTFRRGDIVDIKGNGAVQKGMPHKVYHGR TGRVYNVTQHAVGVIVNKRVKGRILPKKINVRIEHVKHSKCRKEFLDRVEQNEIKKREGR ATVDCKRQPVQPRDGHIVKTRYNKP------------XXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMATQAKVAKSDGKNNHEADKEQQ EAIEQIDEVQNEIDRLNEQASEEILKVEQKYNKLRQPYFGKRSELIAKIPNFWVTAFVNH PQVSALLNEEDEEALQYLTKVEVQEFEDIKSGYKINFSFDENPYFENKAISKEFHLNSSK STPITWKAGKDLTNKSKKRTHEEQESFFSWFSDHGDAGADELGEVIKDDIWPNPLQYYLA SEIDEDNPDDEELEEEE------------------------------------------- -----------------------------------IAQKRGDAVSREVMKKVADDKKMTK QEKDERILWKKNEVADYEATTFSIFYNNALFLVFIIVASFYVLRTFSPTVNYILSMGSAG GLLALFSTST---QGKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQT VCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVKELQRQ ASPNIVIALAGNKADLRMVDYEEAQAYAEENSLLFMESSAKTAMNVNDIFLAIAKK---- ------------------------------------------------------------ -------------------------FEEIFTEMEDKYGEIEEMNVCDNLGDHLVGNVYVR FRYEEDAEKAVADLNNRWFNGRPIHAELSPVTDF-------------------------- ------------------------------------------------------------ -----------------------------------------------------------G CAMSGLIADSRTMIDRARVEAQNHWFTYNEKMSVESVTQAVSNLALQFGDDDADPGAMSR PFGVALLFAGIDAKGPQLFHMDPSGTFIQYDAKAIGSGSEGAQQALQEVYHKSMTLKEAK KEALKILKQVMEEK---------------------------------------------- ------------------------------------------------------------ --------------------SETRVNAQAQAYEYMAAYTESAKQVQRLENAIGWYHSHPG YGCWLSGIDVSTQMLNQQFQEPFVAIVIDPVRTISAGKVNLGAFRTYPKGYKPPDEGPSE YQSIPLNKIEDFGVHCKQYYSLEVSYFKSSFDRKLLESLWNKYWVNALSSSSLLTNADYT TGQMFDLADKLEQSEGQLGRG--------------------------------------- -----LPRRIIKETQRLKAEPVAGIEATPDDSNARYFHVVVLGPKDSPYEGGVFRLELFL PEEYPMSAPKVRFMTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLXIQALLSAPNPD DPLANDVAEQWK------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------KDEQVLKTNC PHIVVGTPGRILALAKSLNLKNLKHFVLDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMF SATLSKEVRPVCKKFMQDPMEVYVDDDSKLTLHGLQQHYVKLKDNEKNRKLFELLDALEF NQVIIFVKSVQRCMALAQLLVEQNFPAIAIHRAMTQEERLNRYQQFKDFHKRILVATNLF GRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLGITFVSDENDAKVPPSYADLG KGARDLFGKGYNYGFYKLEAKTKTNNGVEFTTNGSSNHDSGKFNGTLETKYKWSDYGLTF LEKWNTDNTLGTEITIEDQLVKGLKLSFDTQFAPQTGKKSGKIKTAYKQDHINSNCDVDF DFAGPTINGAAVIGYNGWLAGYQMAFDKSKLSRSNFAVGFKTDDFTLHTSVNDGSEFHGS IYQRVNDELETGVQLNWTAGSNATKFGLAAKYSPDKESSFRAKVNNSSQIGLSYQQKVRD GVTLTLSSLIEGKNFNQGGHKIGVGIDFEA------------EKLLEHKELESRLKEMRE QLKDLTKQYDKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQIDKSK LKAGTRVALDMTTLTIMRYLPREVDPLVYNMSIEDPGAISYSEIGGLSEQIRELREVIEL PLLNPELFARVGITPPKGCLLYGPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIGES ARLIREMFGYARDPHACYLFLVE------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YCCMVGTFPFNSFLSGFISCV GSFVLGVCLRIQVNTQNKSDFYNLSPERAFADFIFAHIILHLVVMNF------------- -LVDKCIGSRIHIIMKNDKEIVGTLLGFDDFVNMVIEDVTEYESTPEGRRVTRLDSILLN GNNITMLVPGGEGPEVIDHYENPRNVGAMDKKKKNVGTGLVGAPACGDVMKLQIEVDDSG KIIDAKFKTFGCGSAIASSSLATEWIKGKSLDEAGKIKNQDIAKELCLPPVX-------- -------------------------------------------------------CTKES FDYLKTLASDVHVVRGDFDENLNYPEQKVVTVGQFRIGLCHGHQVVPWGDTASLAILQRQ LDVDILITGHTQKFEAFEHESKFYINPGSATGAYN------------------------- ----------------MGKFMKSGKVVLVLGGRYAGRKAVIVKNYDDGTSDKPYSHALVA GVDRYPRKVTKRMGKKKIKQRSKIKAFVKVCNYNHLMPTRYSVVNLDKAVVNKDAFRDPA LRRKARREAKSKFEERYKTGKNRWFFQKLRF--------------------------EGF KLVAMKFMWATEEHLKKHYADLSSKPFFNGLVKYMSSGPLVPMVWEGGVVATGRVMLGAT NPADSAPGTIRGDYCIEVGRNICHGSDAVESAQKEIDLWFSKEELVSWAPCTDDWVYEAE PPKPVKTTVKAKEKALKAKKSVLRGVHATRKRKVRTTVHFTRPKTLRLPRAPKYPRKSTP RRNRLDQYKIIKFPLTTESAMKKIEDNNTLVFIVDKRANKPSIKLAVKKLYDINVFKVNT LIRPDGEKKAYVRLAPDYDALDVANKIGIIMPSKQRMRIANEKMAKNVNARGSVPK---- ----------------------------------KIRGWTAVATWRWIANDDNCGICRMP FDGCCPDCKLPGDDCPLVWGQCSHCFHIHCIVKWLNSQQVHQLCPMCRQEWKFKEMIRFI LIQNRAGKTRLAKWYMHFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKVVYRRYAGL YFCICVDVADNSLAYLEAVHNFVEVLNEYFHNVCELDLVFNFYRVYSVVDEMFLAGEIRE TSQTKVLKQLLMLSSLE--TIFSKIIDKSIKADIVHEDDKSLAFRDVSPQAPTHILVIPK KVIPKLSSDQNLLGHLMIVAKKVAESGNGYRIVINDGKDGAQSVYHLHIHILGGRQMEWP P------------------------------------EVGEVVTTIPTIGFNVETVQYKN LKFQVWDLGGQTSIRPYWRCYFSNTDAIIYVVDSMDRDRIGISKQELVSMLEEDELKKSV LCVFANKQDIEGAMTVTEVANALGLSAIKNRKYQIFKTSAIKG----------------- -GLYFHIGEXERKCFIEEIPDETMVVGNYKVEXYDKMQNKYVPTISGLGMHVEVRDPDDK AIMSRTYAAEGRVTFTSHTAGEHIICLHSNSSAWFGGGQLRVHLDIQVGEHANDYQQIAA KDKLTELQLRVRQLLDQVEQITKEQNYQRYRGER-------------------------- -------------------------------------------VKQKLFSEVEGTCTGKY GFVIAVTTIDNIGAGLIQPSRGFVVYPVKYKAIVFRPFKGEVLDAVVTQVNKVGLFTEIG PLSCFISRHSIPADMEFDPNSNPPCYKTKDEDTVIQQDDEIRVKIVGTRVDASDILPLAH SWTYFLGLVS----------------------------------------GKRCCYVYKA QKKTACPGHDNAQSLRVIVGE--------------------------------------- ------------------LIVRFSDDAFNTTFISTIGIDFKIKTVELGGKKIKLQIWDTA GQERFHTITTSYYRGAMGIMLVYDITNAKTFENISKWLRNIDEHANEDVEKMILGNKCDM XDKRQVPREKGDSIA--------------------------------MPQNEYIELHRKR HGYRLDYHEKKRKKESRLAHERAEKAKKLRGIKAKLYHKKRHAEKVQMKKTIK------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------VGVLRKI KAWSDIEKVKASKRFRAGKGKMRNRRRIQRRGPLIIYNQDNGICRAFRNIPGITLLNVAR LNLLKVAPGGHVGRFCIWTESAFKKLDGLYGTWKKPSEEKTNYNLPMTKMTNSDLSRLLR SDEIQKAIRPPKKDKSRKVIKRNPLKNMRIMMRLNPYAAVQKKSAQRKADKQSRLDAKRG IATADAKGKSRPRKAFTSSGEQELATKTLQIQSKRFYLDVKQNRRGRFIKIAEVGAGGKK SRLLLAMSTAAEFRDHLTEFSEHYASLGPPNPDNLPEDGKLKSEVMVKDNRRYYLDLKEN QRGRFLRVSSRSRQRGKSSLDFDFQYEYR------------------------------- -------------------------------------------------------QMRAT VNQKLIETGERERLKELLRTRLVECGWRDELKSKCKDIVRQRGLEHITVDDLVAEITPVG RGLVPDQVKKELLQRIRTFLAQQSN-------PEDLMNMQHCNLLCLPENYQMKYYFYHG LSWPQLSYVAEDEKGKIVGYVLAKMEEDPEDSVPHGHITSLAVKRSHRR----------- ------------------------------------------------------------ ----MSHTILLVQPGRKPEGRTYSDYESVNECLEGVCKIYEEYLKRMNPNSPSITYDISQ LFDFIDQLADLSCLVFEKXSGKYLPTNRA----------------MAEEAGEKKPEETKR VVHTYPLIRHSDMNEEMRTEAMELCVTACEKFSTNNETAAKMIKETMDKKFGASWHAVVG EGFGFEITHEVKNLLYMFFGGNFAIVVWKCS----------------------------- ----KDDSSKPVHMTAFLGYKAGMTHILRETDRPGSKVHKXEVVEATTIIETPPMVVAGV VGYIETPRGLRTFKTIWAEHLNEECRRRFYKNWYSSKKKAFTKASKKWQDESGKKEIEKD FAKMKKYCKVIRVIAHTQMKLLKKRQKKAHIMEVQLNGGTVSQKIDWARERMEKAIPVTE VFGNDEMIDIIGVTKGKGFKGVTSRWHTKKLPRKTHKGLRKVACIGAWHPARVAFSVARA GQKGYHHRTEINKKIYRIGQGIHPKDGKVIKNN--------------------------- ------------------------------------------------------------ ------MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLG LWDTAGQEDYDRLRPLSYPQTDVFLICFSLISPASFENVRAKWYPEVSHHCPNTPIILVG TKLDLREDKETVEKLKEKKLSPITYPQGLAMAKEINAVKYLECSALTQKGLKTVFDEAIR AVLCPKPKPKNKKRCTLL------------------------------------------ -------------------KKKSGSDRDYTYDELLKRVFDIMREKNPDMVAGEKKRFIMK PPQIMRVGTKKSAFANFADICRMLHRQPKHLLAFLLAELGTSGSLDGNNQLIIKGRFQQK QIESVLRSYIKEYVTCHTCRSPETILQKDTGSTFFSVRPADSRCSVQSIQ---------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------SGECHPELRLKGHQKE GYGLSWNPNVNGNLLSASDDHTICLWDINSTPRDGKCIDAQTVFTGHTSVVEDVSWHLLH DSLFGSVADDQKLMIWDTRSNNTNKPSHTVDAHTAEVNCLSFNPYSEFILATGSADKTVA LWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSG---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------YLFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLA EFYHPGQEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPFFHGHDNY DQLVRIAKVLGTEELFEYIDKYQIDLDARFNDILGRHSRKRWERFVHSENQHLVSPEALD FLDKLLRYDHQERLTAREAMGHPYF------QVPETLLKKRKANEERNHDKRKLMFRRAE KYIKEYRIKERDEIRLARQARKHDNYYVPPQPKVAFVIRTRGINGIHPKPRKVMQLFRLR QINNGVFVKLNKATIQMLRLAEPYITWGYPNQKSVRELIYKRGYGKLDNRRIALTDNAII EEKLGKYGIICMEDLIHEIFTVGPAFKYANNFLWTFKLNTPNGGWRKKNNHYVDGGDFGN REDKINALLKRM-----------------------------------------KPKMCSF LEWKDLKIVYKRYASLYFCCCIEADDNELLTLEIIHRYVELLDKYFGNVCELDIIFNFEK AYFMLDELLLGGEVQETSKKNVLKAIAAQDLLQEEEPKGILEELGL-------------- --------------------------------------------GMVVVRGNSIVLLESL DRIEFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTI RLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFQQTSKWIDDVRTERGSDVIIM LVGNKTDLSDKRQVSTEDGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMEQTE- -----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLVDEA TKKTLAKIPLCKTKAGPRDGDLWVQRLKEEYQSLIKYVQNNKESDNDWFRLESNKEGTRW FGKCWYIHELLKYEFDVEFDIPVTYPTTAPEIAIPELDGKTAKMYRGGKICMTDHFXLYG ARNVGKFGIAHAMALGLGPLLAV---------------XXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------------- ------------------------------------------------------------ -----IVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEY ADQLGIPFLETSAKNATNVEQAFMTMAAEIKNRMGPVPTAPNVKITDSTPVKSS------ ----------------------DNEIKIMKSEVMRISHELQAQKDKIKENAEKIKVNKTL PYLVSNVIELLDVDPQDQAEEDGANVDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDPEQL KPGDLVGVNKDSYLILETLPAEYDSRVKAMEVDERPTEQYGDIGGLDKQIQELIEAVVLP MTHKERFETLGV------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------GASELCHEDYMDAILEVQAKKKANLNYYAXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------WYETDFYNXQIYPPINVLPSLSRLMKSAIGEGMTREDHADVSNQLYACYAIG KDVQAMKAVVGEEALTSEDLLYLEFLQKFEKNFIAQGPYENRTIFETLDIGWQLLRIFPK EMLKRIPAGILAKFYPRDSSGPGFVGIKFCQECNNMLYPKEDKENKILLYACRNCDYQQE ADNTCIYVNKIQHEVDALTQIIGDVIADPTLPRTEDHP---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------IKGLSEETTTGVHNL YKMMAAXELKVPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGKVACVAGYGDV GKGCAQALRAFGARVLITEIDPINALQAAMEGYEVSTIEDALPEARIFVTTTGCKDILHG QHFSNMLEDTIVCNIGHFDCEIDVKWLNDNCASKENIKPQVDRYTLKNGRHLILLAEGRL VNLGCAMGHPSFVMSNSFTNQVLAQIELWTNTAKYPLGVHFLPKKLDEEV---------- ----------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXMSTSNVENFSPQIIRQVAKELSELQKEPPEGIKVIPNEEDITDIQAHIEGPAG TPYAGGFFRVKLVLGKNFPSEPPKGFFLTKIFHPNVAKSGEICVNTLKKDWKAEYGVKHI LLTIKCLLIVPNPESALNEEAGKLLLEQYEDYSMRAKLITEIHARP-------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------KLLAEEGWW GFYKGIVPLWGRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKAEQLVVTFVAGYIAG VFCAIVSHPADTIVSKLNQDKGSSVGEVARKLGMAGLWKGLGPRIIMIGTLTALQWFIYD SVKVYFRLPRPPPPEMPESLKKKL-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------- ------------------------------------------------------------ ------------------------------------------------------------ -----MLNGVPLSDAALLLIAXNDHALTPQTSEHLAAIEIMKLKHIFIIQNKIDLVKESQ AQEQYEQIIRFVQGTIAEGAPVIPISAQLKYNIDAVCEYIVKKIPIPTRDFISQPRLIVI RSFDVNKPGCEVDDLKGGVAGGSILCGVLKVGQEIEVRPGLVSK---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------QALIRSRLLRENGRFLPLQGMLMRKNFFNNESSGYFVKNPMT DPSMMTDMMKGNLTNVLPMIVIGGWINWAFSGFLTTKVPFPLTLRFKPMLQRGIELVSLD ASWVSSVSWYFLNVFGLRSMYNLILGQDNAADQTRIMQDQMTGAAMGMPPDPSKAFKAEW EALEITEHHWALQGVEEEVMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--- ------------------------------------------------------------ ----------------------RRILKVDQGTLFELILAANYLDIKGLLDVTCKTVANMI KGKTPEEIRKTFNIKNDFTPAEEEQVRKENEWCEEKNKRLSKGGKKGSKKKIVDPFSKKD WYDVKAPSMFMVRQIGKTLVTRTIGTKIASDGLKGRVFEVSLADLQNDEYSFRKFKLVAE DVQGRNVLTNFHGMNMTTDKLRSMVKKWQTLIEANVDAKTTDGYLLRMFCIGFTTKRPNQ IKKTCYAQSTQVRSIRRKMVDIMTREVTSNDLKDVVHKLIPDSIGKDIEKACQGIYPLHD VCIRKVKILKKPKFDLGKLMDMHGEGSSTVTTEGGEKVERPDNYEPPVLETV-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ESVIERHQHSRVEYMIKAKSQFKRRSTANN VEILIPVPQDADSPKFKTTAGSCKYAPDQNVVIWTIKSFPGGKEYLMRAHFDLPSVESED TEGKPPIHVRFEIPYFTVSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRTQ------ --------------------LGLLKARLAKLRRELIEPXGGGGATGEGFDVAKTGDSRIG FVGFPSVGKSTLLSNXAGVYSEVAAYEFTTLTTVPGCIKYKGAKVQLLDLPGIIEGAKDG KGRGKQVIAVARTCNLIFIVLDVLKPLQHKKLIEHELEGFGIRLNKSPPNISFRKKEKGG VNLTTT---------LVQMILHEYKIFNAEVLFREDATADEFIDVIQGNRIYMPCLYVFN KIDQISLEEVDRLARQDNTVVVSCNMKLNLDYLLERMWEYLDLVNVYTKXRGERPDLENG IILRNG-CSVEHVCHAVHRTV--------------------------------------M AKHHPDLIFCRKQPGVAIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGSYQGRCVIC GGPGVSDAYYCKECTIMEKDRDGCPKIVNLGSAKTDLFYERKKYGFKKR----------- ----------------------WMKIFTPIVEHLHLQIRFTXKDKKCRIKSCKDTTDIGA LQKGADFVKAFTLGFEVEDALALIRLDDLYLESFEITDVKPLKGDHLARAIGRIAGKGGK TKFTIENVTKTRIVLADSKIHLMGSFQNIKIARTAICNLILGSPPSKVYGNMRAVAARSA ER---------------------------------------------------------- --------------------------------------IRNILGGTVFREPIICKTIPRL VPGWTQSIVIGRHAHGDQYKATDFVAKGSGKFEMVYTPTDGGEQRWEVFNFKD-GGVGM- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------FAWTRGLEHRAMLDNNPELARWCQVMEK SCVDTVDSGKMTKDLAGCIYGLKNVTPDQYLNTGDFLDAI-----MGKLLSKIFGNKEMR ILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWR HYYTGTQGLIFVVDCADRDRID-YETELHRIINDREMRDAIILIFANKQDLPDAMKPHEI QEKLGLTRIRDRNWYVQPSCATTGDGLYEGLTWLTSNAKSFGNLKSDAGVQALNNYLADK SYIEGYVPSQADSAVFQAMGSPNAKYVNALRWYNHVKSYGNEINSLPGVKKPIDEYGPAS TKADDDDDDFDLFGSAAEKLKQERLAAYAAKKAPVLIAKSNIILDVKPWDDETDMAELEK CVRSVETDGLLWGASKLVPVGYGIKKLQISCVVEDDKVGTDFLEERLTEFEDYVQSVDVA AFNKV------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------EEGKAEIVPGVLFIDEVHM LDIECFSFLNRALESDMAPIMIMATNRGITRIRGTNYNSPHGIPIDLLDRLLIIATSPYE EKEIKQILKIRCEEEDVEMSDDALTVLTRIGLETSLRYAIQLITTAPPLQPKRKGXEVSV DDIKRVYSLFLDESRSTVY----------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------SSLQSLQQRTWLI HWSLFVFFNHQKGRDLIIDMFLYQPQYLNAIQTMCPHVLRYLTTAVITNKTVLKDLVKVI QQESSTYRDPITEFLECLYVNFNFDGAQQKIXKAKTVLVNDFFLVACLDDFIENARLFIF ETFCRIHQCISIKMLADKLNMTPDDAERWIVNLIRNARLDAKIDSKLGHVVMGTQAVSPY QQVIEKTKXLAFRSQMLVMNIEKKLGAKQMGVELESLKEGDGTTFPKQGQVVIVHYTGTL TDGSKFDSSRDRGQVFKFRIGKGEVIKGWDEGIKRMSLGQRARLTCSPDYGYGKRGYPGV IPPDSSLIFDIELI---MPKYYCDYCDTYLTHDSPSVRKTHCNGRKHKENVSVYYQKWLE EQVQKLVDDTTAAFKAGGGNNK-------AVPPPASQAGAPP------------------ -----------------------------------------FQKLQALQKVLQSEFCNAV REVYEHVYETVDISGSPEVRANATAKATVAAFAASEGHAHPRVVELPKTEEGLGFNVMGG KEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGVSVEGEPHEKAVDLLKAAQGTVKLV VRYT---------------------ILSVVAVALTEPTVYFKETFWEQRWVESTHKGSEA GKFKLSAGKFYGDAEKDKGIQTSQDARFYALSSKFEKPFSNEGKTLVVQFTVKHEQNIDC GGGYVKLFSSDLDQKDMHGESPYNIMFGPDICGPGTKKVHVIFNYKGKNLLVKKDIRCKD DVFSHLYTLIVRPDNTYEVKIDNKKVESGDLEADWDFLAPKKIKDPEAKKPDDWDERETI DDPEDSKPDDWEQPEHIPDPDAKKPDDWDDEMDGEWEPPMIDNPDYKGEWKPKQIPNPAY KGKWVHPEIDNPEYSPDDKLYKYDDFGVIGFDLWQVKSGTIFDNVLITDDEKYAEEFGEE TWGATKDGEKKMKDAQDEEDRKKREEEEKKRKEEEEDEEGEEEE---------------- -------------------------------THRANAEIIMLEGLTCVYRSNVDLFFYVI GSSQENELILVSVLNCLYDSVSQMLRKNVEKRALLDNMDGVFLAVDEICDNGIILESDPS AVCQRVSFRSDDIPLGEQTVASVIQSAKEQIKWSLLK----------------------- ------------------------------------------------------------ ---DCNHDTFRMEFLIVPVAGLAFLVNHDFSPLEILWTFSIYLESVAILPQLFMIGKTGE AETITSHYLFALGSYRGLYILNWIYRFYFEXFFDLIAVVAGCVQTVLYCDFFYLYI---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------EYVPLPKGDVHKK KEVIQDVTLHDLDIANARPQGGQDIISMMGQLMKPKKTEITDKLRKEINKVVNKYIDQGI AELVPGVLFIDEVHMLDIECFTYLHRALES--------------CTIRGTENMVSPHGIP LDLLDRLMIIRTLPYSKEEMQQIIRIRAQTESITLNDESLALFTQIGVKTTLRYAVQLLT PSNLLTRINGKDSIGKEEIEEINELFFDAKSSAKILSEQEDKFMKXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMA GSALKRLMAEYKQLTLNPPEGIVAGPMNEENFFEWETLITGPVGTCFEGGVFPARLVFPA DYPLSPPKMKXTCDLFHPNIYPDGRVCISILHAPGDDPMGYESSAERWSPVQSVEKILLS VVSMLAEPNDESAANVDAAKTWREDRVKXEEIAHRTVRKSLGLMRLDKCYFCSSTVYPGH GISFVRNDCKVFRFCRSKCHKAFKKKRNPRKVKWTKAFRKSAGKELSVDPSLEFEKKRHV PIKYEREVWKKTVDAMKRVEEIKQKRQGQYIANRLKKGKELRKARDIKDVKESIHLIKSP A----------------------------DADLSDLGIQEAKSAGQMLKKEGYSFDVAYT SLLKRAIKTLYYVQDELDLHWIPVTRHWRLNERMYGALQGLNKAETAAKHGEEQVKI--- ----------------------------------------VQRVMVVWHDYIVPDILKGE RVLVVAHGSGLRALRKYLEGISDEDVMGLNIPTGIPLVYTLDADLRPVAQQYLADEATVK AAVDKIANQASLKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------- -----------------ATLGSGNLRMAVQLPEGEDLNEWVAVNTVDFFNQINMLYGTIT EFCTEDTCPVMSAGPKYEYHWADGTTIKKPIKCSAPKYIDYLMT---------------- -VPFPKNFLSIAKTILKRLFRVYAHIYHQHFQQVIQLQEEAHLNTSFKHFIFFVQEFNLV DRRELAPLQELIDKLSSKDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXDLKQGNIPGSFLIANTVCLLRRIVSQLKWANAR ELMDVIKQEGSKLVSNHPSETTIGNMVRRVLKIIREEYIIEAVLEFITELETSGQALEHI HSNEVIRTVESFLKRKFHVIVVEYHGQQVAMSLAEAGIETTVITDSAVFAFFFCXNKVII GTHTVMANG--------------------------------------------------I HNPVFDYVPPELVTLFISNIGGNAPSYVYRLLSELYHMIIPIRCFTCGKVIGNKWEPYLG LLQAEYTEGDALDALGLKRYCCRRMLLAHVDLIEKLLNYAPLEKKSPEAVEGRKHIDVQT ELYLEELSDRVEEADVEVQTDAFLDRPPSPMFVPAKTGLDMATQILEGELFDFDIEVKPI LEVLVGKTVEQALLEVMEEEELANLRSQQREFEELRNAELVEQQRLEEQERRHREEKERR MKQQKEILRKE------IAARAFAQSYLADLVPSVFGTLSDNGYFYDPVERDVEQGFMPW LMDRVSDTLTKSVLGRTVLDGILREVVAKRREEYSKXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSAHDQMKEFWKKNQNRPSSPWIIYKPHL PMLTSLTHRVTGVSMGIVLYAVSIGTFVAPGDFASYIEFIKGLEISPIIMFPAKTILA-- ------------------------------------------------RDQHFKGSRYEQ EQLLTTTTTLYVGNMSYYTTEEQLYELFGRAGDVKRIIMGLDKFKKTPCGFCFVEYYTRE DAENAVRYINGTRLDDRIVRTDWDAGFREGRQYGRGKSGGQVRDEYRTDYDSGRGGYGKI VQQKL------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------KYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG KWIVSGSEDNTVYIWNLQTKEI--------DVVLCCACHPXENIIASAALENDKTIKLWR SDVMIIYKDLISGDELFSDTYPGAVYKVKGKSDAMFGGNASSGVNIVLAGKKDYKVYIKD YMKRIEGFEFYLGVCLLRWESPYMYFFKHGLEAEKVMAVEFSDGVIFGADSRTTTGSYVA NRVTDKLTKVTDKIYCCRSGSAADTQAIADIVQYHLNIHKIEMG---------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------KAKDAKKGLKGAVDLKSVQLLGNAYKEKVQPDLDELEVNMEDNE DAESQKSVEKLGKLQFSLDYDFQKGELTVGVIQGADLPGMDMSGTSDPYVKVYLMPDKKK KHETKVHR---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------VTNSPVIFIGTGEHIDDLEPF KVKPFVSKLLGMGDIEGLMEKVNDLKLEDEELMNKLKH---------------GQFTLRD MYEQFQNIMMSILAYNGAAVIAMKGKDCVAIAADRRFGIQAQTISMDFQKIFEMGPRLYV GLPGLATDVQTVSQRLKFRLNLYELRENRKIKPKTFMSMVSNLLYERRFGPYFVEPVIAG LDPKTMEPFVASLDLIGCPMVTDDFVVSGTCTEQMYGMCESLWEPDMTPDVLFEKISQAL LNAVDRDAVSGWGGVVHIIEKDKVTTRTLKARMDMTSKDYYFDSYAHFGIHEEMLKDEVR TLTYRNAMYHNRHLFKGKTVLDVGCGTGILCMFAAKAGAAKVIGIEMSSIVQYAEQXVKA NKLDHIXKLVKGKVEEVTLPDGIEKVDIIISEWMGYCLFYESMLGTVLFARDKWLAPGGL IFPDRATLYICAIEDRTYKDEKINWWDSVYGFDMSCIRKTAISEPLVDVVDPKQVVTNSC LVKEVDIYTVKEEDLTFKAPFHMTCRRNDYIQAFVTYFNIEFTKCHKRTGFSTGPESRYT HWKQTNDFMTVKAGEEIYGVMSIMPNKKN----------------------------MVK EDRSTWKAGYFTKIISLLDEYPRCFLVGADNVGSKQMQQIRIALRVLMGKNTMMRKAIRS HLENNPALEKLLPHIKGNVGFVFTKGELTDIRTIIDENKVAAPAKAGAVAPLDVTVPAQN TGLGPEKTSFFQALAIPTKISKGTIEILNDVKLIKAGDKVGASEATLLNMLKISPFKYGL LIEQVYDSGTIFDPTILDVTDDDLRGRFMAGVTNIASVSLAIGYPTVASVPHSIANGFKN LLAVAAETEITFKEAETMKE---------------------------------------- -----------------RDDIAIILISQNIAEMIRHALDNHTQPIPAVLEIPSKDHPYDA SKDSILRRAKGMFSAEDFR----------------------------------------- -------------------------------------------------LRFAFKIYDMD KDGYISNGELFQVLKMMVGNNLKDAQLQQIVDKTIIHADTDGDGKIXFEEFCAVVGTLDV HKKMVVDVMTYLNSWEEFAKAAERLYVADPMKCRFVIKYQHNEGQLYVKITDDQVCLQYR SEHAQDVKKIEKLTSQLMRSMASKELYEEVKLYRNARERERYDNMADLYAVINTLQVLEK AYIKDSVTPKEYTAACSKLLVQYKAAFKQVQGDEFPTVEAFMKKCKLDCPAALVRIKEDR PITIKDDKGESTR----------------------------------------------- -----------------------------------------------MLSSMLKEHQTRQ LIRKEIQEKRKKEATQATALSHALVDHLNAGVAQAYVNQKKLDTETKILKANANQ----- -------------------------------------------ARFVVKKIGGDKNGGER KVRVNRMPRFYPTEDRPRKLTSPFGQHKRSLRTSITPGTVLILVAGRHKGKRVVFLKQLA SGLLLVTGPYHLNGCPLRRINQIYVIATKTKVNISGVKLPDRLNDEYFRRNKLKKPKHTE GDIFETKKETYSVSEERKQDQVEVDKQILDAIRKNKEKKLLFGYLGAMFSIKNGQYPHKM VF----------------------------------------------------QGQMDA VKIMAXDLVRTRRYVKKFILMRANIQAVSLKXQTLKSNDAMAQAMKGVTKAMATMNKQLK AXRRFKIMMEFEKQSEIMEMKEEMMNDAIDDAMGDEDDEEEGEAIVSQVLDELGLQMADQ LSDLPGTGQSAGKTPVGVSDADADLEARLDNLRRQXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------RKVRDVYWKVYNTCYIGAQDAMIPAYPRIQNDE KNMYERYELDYLL----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------SQLLEIYALEIQMYTEQKNNKKLKALYEQSLHIKSAIPHPL IMGVIRECGGKMHLREGEYEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGIN PFDSQEAKPYKNDPEILAMTNLVSSYQNNDINEFEKILKTNRRNIME--------EDLLR NIRTQVLIKLIKPYTRIHIPFVSKELNIDVAEVENLLVSCILDSTIHGRIDQVNQVLELS XGIARYNAMDKWTEQLSSLHLAIVNKM-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXX--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------LGFETDLRTHTQGQAFCLSVFHHWQIVPGDPLDKXIIIRPLEPQPAT HLAREFMIKTRRRKGLSEDVSINKFFDDPMLLEXAKQDVMLSYGMQDVFSLFDNKGDGKV YAHQLGDVLRAMGQNPTEAEVKKCQDPDYRISFEQVLPIYATISKNKDTSSVEDFVEGFR VFDKEQNGTINSAELRHLLTALGE------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ALAFEADRRAFHHYHQSFGTELSKDDRAKLYPRCGR LYPXGLASLARADDYEQVRXLAEYYAEYKVLFEESGNNPRQNSLEDXFFEHEVLLMKNAF MQQFHFGSFYAYVKLKEQECRNIIWIAECVAQRHRAKIDSYIPIF-------KISKIPFK VLDAPELQDDFYLNLVDWSSQNVLSVGLGSCVYLWSACTSQVTRLCDLSCDGDSVTSVSW SERGNLVSVGTHKGHVQIWDVSSNKRVSVLEGHSARVGALAWNADVLSSGGRDRLILQRD IRTPSIVPERRLTGHRQEVCGLKWSPDHQHLASGGNDNKLFVWNXTSVNPVQTYTDHLAA VKAIAWSPHQHGLLASGGGTADRCIXFWNTLTGQPLQSVDTGSQVCNLAWSKHSNELVST HGYSQNQILVWKYPSLVQIAKLTGHSFRVLYLAMSPD----------------------- ----------------RLVFIALYYLFTGQGYRVDIGWFLAGIPPYLWANLGIGMAISLS VIGAAWGXFTTGASILGAGVKAPRIRTKNLVSIIFCEAVAIYGIIMAIVISNANNYFAGY AALGAGLTVGFANLVCGICVGIVGSGAAIADAANASLFVKILIIEIFGSAIGLFGVIVSI LQISHAHMGNK------------------------------------------------- -----------KIYHPNIDEKGQVCLPIISAENWKPATKTDQVIHSLAALVNDPEPEHPL RADLAEEFTKDRKKFHKNAEEFTKKHAEKRPSDGASQTFPMQCSALRKNGFVCIKGKPCK IVEMSTSKTGKHGHAKVHLVGIDIFSGKKCEDICPSTHNMQVPNVSRIEYEVVDFNEGFF SLMDEASNIRDDLKHTATVWKALGEEYVKELK---------------------------- ------------------------------------IVISDHNNHKVKIFTQGQIIQTYG EKGVEVGQLHNPCGVCADPKGRILVCDWGNQRVLRFETRGSLL----------------- ------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXX------YLLAVLGGNESPKEADIKKILSSVGVEADAECIKR VIGELAGKDVEEVIAAGKEKLASVPSGGGVAAAEEKKEEEEDDDMGFGLFD--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------CNALLLKVNQIGSVTESIEACKMSQEAGWGVMVSHRSGET EDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGPKAKYAGVNFRNP----- ------------------------------------------------------------ -------------------------------------ALSMRHLAVMCTTLKVLQHLVVS ADMVGEALVPYYRQILPVLNIFKNKNLNSGDGIDYSQQKRENIGDLIQETLEAFERSGGE DAFINIKYMVPTYESCMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXX----RLWDKDEYERLAQERLEAELGKKDPPIKRDLLRPREYRVDLDS KLNKSQVITKTTPSSQQGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRIERSSLD QVKARFEANKKKKKKKK------------------------------------------- --------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------- -------------FTXKKFMADCPHTIGVEFGTRIIEVAGQKIKLQIWDTAGQERFRAVT RSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIFLIGNKSDLEAQRDVTYE EAKQFADENGLMF----------------------------------------------- -----------------------------PIEGKVLFEQEDETQIKVSLTGFDYNTHGFH IHEKGDLGEGCKAAGGHYNPANVDHAGPEDAIRHVGDLGNVEEDETTKTDN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----HNLKVMKFSVSPVVRVAVECKNPSDLPKLVEGLKRLGKSDPLVQCSIEESGEHII AGAGELHLEICLKDLEEDHACIPIKVSEPVVSYRETVSEESDRMCLSKSPNKHNRLFMKA RPMPDGLPEDIDKGDVTPRQEMKERARLLADKYDYDVTEARKIWCFGPEGTGPNLVIDCT KGVQYLNEIKDSVVAGFQWASKEGVLCEENMRGVRFDIHDVTLHADAIHRGGGQIIPTTR RVLYACVLTAQPRLLEPVYLVEIQCPEA-------------------------------- -----------------------------------------------------------X XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- -------------------------------------VDCVEFVLEVNVIITGSWDSTVK LWDPRTPCCAGSFTQPERVYTMTVCGDKLIVGTAARRVLVWDLRNMGYVQQRRESSLKYQ TRCIRSFPNKQGYVLSSIEGRVAVEYIDPSPDIQKKKYAFKCHRIKEDGVEKIYP----- ------------------------------------------------------------ --------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXX------------------------------------------------ ------------------------------------------------------------ --------------------------VLVNITEHQLVPEHVLLTPEENKNXLQGYKLRNH NYPELQMGDPVARYFGLKRGHVVKIVRPSETAGRYITYRLVV--------VIGIDLGTTY SCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDVKRLI GRRWDEPSVQADVKFXPFKVTNKNSKPQIVVNTGSEEKEFAPEEISAMVLTKMKEVAEAY LGKKVTHAVITVPAYFNDAQRQSTKDAGTIAGLNVMRIINEPTAAAIAYGLDKKEGEKNI LVFDLGGGTFDVTLLTIDNGVFEVLSTNGDTHLGGEDFDQRVMDYFIKLYKKKKGMDVRK SNRAVQKLRREVEKA--------------------------------------------- --------------------------------------FNGKEPSRGINPDEAVAYGAAV QGGVLSGEEDTGDLVLLDVNPLTLGIETVGGVMTKLIPRNTVIPTKKSQIFSTAADNQPT VTIQVYEGERPMTKDNHILGKFDRNSV-LRPRGVPRLEVTFXIDVNGILKVTAEDKGTGI RTTLLSNNDQNRLXPEDIERMINDAEEISDEDAQVRKRVEARNELESYAYSLKNQINDKK SL---------------------------------------------------------- ----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXX-------------------------------------------------------- KKEKETEVQQRNEMIAHLKDQLQEMKAKTNMEGKYIKKCAEVSVAQTQKRCNIGEKECRD EIESLKEKIDEENRVNAEIESFLRAHTEGLQKMVEYWMEKYEKDVELKQKELDILKASKA KDLERLQELTKLYTEYEQVVVEDRIEKEKARRKAEQEAEELRASIRVQSWWRGVMVRKGL GPYSKKKRRK-------------------------------------------------- ------------------------IPWGKSGAEYVVESTGVFTTIEKAKAHVAGGAKKVI ISAPSADAPMFVMGVNEEKYEKSMEIISNASCTTNCLAPVAKVIHDNFTIVEGLMTTVHA YTATQKTVDGPSAKAWRDGRTAGQNIIPASTGAAKAVGKVIPSLNGKLTGMAFRVPTPDV SVVDLTCRIEKGATMDEIKATVKGPMKGILGYTEDQVVSSDFISDTHSSYFDARAGIALN ANF--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------LVQYPVEHPDKFLKFGMTPSKGVLFY GPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVRDIFDKARSAAPCVLFXD ELDSIAKARGGNVGDGGGAADRVINQLLTEMDGMSSKKNVFIIGATNRPDIIDPAILRPG RLDQLIYXPLPDDKSRVQILKANLRKSPVAKDVDLDFLAKTTQGI--ADLTEICQRACKL AIRESIESEIRRERERADNPDDYDSVPEIRRDHFEESMKFARRSVTDNDIRKYEMFAQTL QQSRGFGG---------------------------------------------------- -----VRCWEVQQNGQTIPKAQQTHTGPVLDVCWSDDGTKVFTASCDKTAKIWDLNSNQA IQVAQHDAPVKACKWVKAPSYSCLMTASWDKTLKFWDTRTPNPMMTIQLPERAYCADVLY PMAVVGRLXRSDYLVQLENSTPKFKRIESPLKYQHRCVSNFLDKKQXSPTGFALGSNEGR VAIHYVNPTNPKDNFTFKCHRGGVQDIYAVNGISFHPVHGTLATVGSDGRFSFWDKDART KLKTSEQLDQPISCCSFNAQGNIFAYASSYDWSKGHEGFDPQKMKPHIFLKSCYDELKPS QKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMDE QEILTTLKILIIGESGVGKSSLLLRFTDDTFDPEQSATIGVDFKVKTLTVDGNRAKLAIW DTAGQERFRTLTPSYYRGAQGCILVYDVSSRSTFTKLENWLNELETFSTKHDIIKMLVGN KIDKDRREVTR------------------------------------------------- ------------------------------------------------------------ ------------RLVEKVKLSRNYEKALKQIDEHLIYWPRFLKHKCKQRFTKITQYLIRM RKLVLKRQKKLVPLSKKVERRDARRQEKALVAAQLENAIEKELLERLKKGTYG------- ---------------------------------------XXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- ------------------------------------------------------------ ------------------------------------------------------------ ----------------LVLSMLFNQFPGFKEVRLVPGRHDIAFVEFENEVQAGAAKDALQ GFKITPTNAMKISFAKK------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GFEIEQEQKLALETTVLVESYTLPDGRVIKXGGERFEAPEALFQPHLINVEGVGVAELLF NTIPXQDIDTRAEFYKHIVLSGGSTMYPGLPSRLEREIKQLYLERVLKGNTESLTKFKIR IEDPPRRKHMVFLGGAVLGDIMKDKESFWMTRQEYQERGLHIMEKLGVS----------- ------------------------------------------------------------ -----------------------LYIPQCGECKFCKSPKTNLCSKIRSTQGAGVMPDGTS RFTCNGKQLYHFMGTSTFSEYTVVADISVAKVDPKAPLEKVCLLGCGISTGYGAALNTAK VEKGSTCAVWGLGAVGLATAMGCKAAGAARIIGIDINPSKFETAKTFGVTECVNPKDFDK PIQQVLVDMTDGGLDFTFECIGNVATMRAALEACHKGWGVSVIIGVAAAGQEISTRPFQL VTGRVWKGTAFGGWKSRESVPKLVEDYLSGKMMVDEF----------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------SVPIYEGFAMPHSIM RTDIAGRDVTRYLQLLLRXEGHNLHTTAEFEIVRSIKERACYLSINPQKEETLETERAPF XLPDGSVVEIGPARFRAPELLFRPDLIGEEYEGIHEVLAFAIQKSDMDLRRTLFSNIVLS GGSTLFKGFGDRLLSEIKKLAPKDIKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKR EYDEEGARAL-------------------------------------------------- ------------------------------------------------------------ LINELLRKYCPNSVLVIIDAKPKDLGLPTEAYIAVEEVHDDGTPTTKTFEHLPSEIGAEE AEEVGVEHLLRDIKDTTVGTLSQRVTNQLMGLKGLFSQLNDVHSYLEKVVSGKLPINHQI VYQLQDVFNLLPDVDFQEFVKAVYVKTNDQMLVVYLASLIRSIIALHNLINNKIQNSDAE KNEGKSEKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXX--IPIRRVQLSDPSQLPSDYSQTPGGTLFSTTPGGTRIIYDRXFLMQCRNSPLA KSPPPNLPKIPGVTSP-------------------------------------------- ------------------------------------------------------------ ----------------------------------------LETGQVLGLVSGHVKTQLIA HDKEVYDIHFSRXGGGRDMFASVGADGSVRXFDLRHLEHSTIIYEDPQHHPLXRLAWNKQ DPN--XXXXXXXMEVIILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHIXTAADDHQAL ISXIQQMPRAIEDPILAYTAAGEINQIQWSLAHPXWISICYNNCMEILR----------- ------------------------------------------------VKGYVGPDQLGE CVEGSDVVVIPAGVPRKPGMTRDDLFNTNASIVRDLADACAQYCPKAMICIISNPVNSTV PIASEVFK---------------------------------------------------- ------------------------------------------------------------ --------------------------------KNLGLGKLLEYEVNLIKAAMPELEKNIQ KGEDFILK---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------SANKGEIGDATPFNDTVNVQKISNLLHE YGYHLRGNEVLFNGHTGRKLNAQIFLGPTYYQRLKHMVDDKIHSRARGPVQILNRQPMEG RSRDGGLRFGEMERDCQIAHGAAQFLRERLFEISDPYRVHVCNICGLIAIANLRNNTFEC RGCKNKTQISQIRMPYACKLLFQXLMSMSIAPRMMV---------------------KGF KPPKVYKTGTTICGIIYKDGVVLGADTRATEDTIVADKNCSKIHYIADNIYCCGAGTAAD ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------MSKVTFKI TLTSDPKLPYKVLSVPEQTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPAQSAGNVFL KHGSELRLIPRDRVG--------------------------------------------- ------------------------------------------------------GLYDPT TIMNADELSRAQKEGWIKLAFYLLSFFYYLYSMIYELVSSMGLLTILKKMKQKEREVRLL MLGLDNAGKTTILKKFNGEDIDTISPTLGFNIKTLEHKGFKLNIWDVGGQKSLRSYWRNY FESTDGLIWVVD------------------------------------------------ -LELDNIKTHHWLIQGCSAVTGENLLSGIDWIIDDIASRIFTMD-----VCYYYDGDIGN YYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIKFLRSIRP DNMSDFNKQMQRFNVGEDCPVFDGLYEFCQLSTGGSVAGAVKLNKQATDLAVNWGGGLHH AKNTEASGFCYVNDIVLAILELLKYHQR-------------------------------- -------------------------------------------------------LVLQC GADSLSGDRLGCFNLSLKGHGKCVEFMKKYNLPLLMLGGGGYTIRNVARCWTYETSVALG VDIANELPYNDYFEYYGPDFKLHISPSNMANQNTPEYLDKIKTRLFENMRMLPHAPGVQM QDIPEDAVKDEQDPDRRISIRDSDRR-----------------------------XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------------- --------PKIVAAAMKACRRLNDYALAVRYLEAVKDKCGNQVGTIWPYMTQQLKPTLDE LGILTPEEMGYDKPELALQDVYDIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----FSQKTAGYGGPNKIEKAKIGLIQFCISPPKTDMENNVIVSDYTQMDRVLREERQYI LNIVKQIKKAGCNVLLIQKSILRDAINDLALHFLAKMKIMVXKDMNLKXIEFVCKTLGCR PTASVS------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------VSAVHLAAE TVRSILKIDDIVNCQ--------------------------------------------- ------------------------------------------------------------ EKSAESASLLKRHCFASVFEKYFQFQENHKRAVIQYRDDETMYVDAQKDRVTVIFSTVFK DDDDIVIGKVFMQEFKEGRRRYQQGPQVLFSHKTTXLR----TMQTGDNIGYITFVLFPR VENRDNTINLIHTLRDYLHYHIKCSKAYIHSRMRAKTSDFLKVLNRARPQSKTVAKKTIX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------- --------------VSRGDWYKTKEIILKGHEWIQNEVKVSGLRGRGGAGFPTGMKWSFM NKPDDGRPRYLVVNADEGEPGTCKDREIMRHDPHKLIEGCLVAGSAMGACAAYIYIRGEF YNEASNVQLAINEAYKAGLIGKNACGSGYDFDVYLHRGAGAYVCGEEXSLIESIEGKAGK PRLKPPFPADIGVFGCPTTVNNVETIAVAPTICRRGGEWFASFGRPRNTVALLEFDDLVA HKTALGTAALIVMDKSADVIKCIARLMEFYKHESCGQCTPCREGVSWMNSVLQRF----- ---------------------------------------------------------QVD DMNQQLNQTRSQRVRAAMFPETLEENMQIPSPQIHPDQQTAVQRLAEPSQMLKHAVVNLI NYQDDADLATRAIPELTKLLNDEDQVVVSQACMMVHQLSKKEASRHAIMNSPQMVSALVR AMSNTXDLETTRCAAGTLHNLSHHRQGLLAIFKSGGIPALVKLLSSPIESVLFYAITTLH NLLLHQEGSRXAVRLAGGLQKMVALLQRNNVKFLAV------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRGE QXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXDEPYYCSEQISIPPELPDILKQFTKAAIRTQPKDVLAWSAAYFRSMANGETPP VKERLEMPVATQKTDTGLTPGLLRVLNKQLGPKKNVPLTLIEEKWKDLALPKEQFDELVR IGSFGGEIEWLKFFALASSALGENISDAMKTVCEILTADPDGGPARIPFPLFQELYKYLA QVDGEISQEHINTVINYLMYHVDKQDGFVQPRNFLSSDCPSLS----------LMEQVKA QIAVANAQELLQKMSDKCFAKCVQKPGSSLDSSEQKCVAMCMDRYMDAWNLVSRAYTQRL QRER----------------PPNLNDCISNIDSRGESIDKKISRLDQELAKYREQMKKMR DGPSKNMVKQKALRVLKQKRMYEQQRESLMQQSFNLEQSNYAIQTVKDTKTT-------- ------------------------------------------------------------ ------------------------------------------------XXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- -------------------------------------------------TRLVRILLNHF KWDREKLMECYYDGESXNCFREAHVISPFKKTLETLCEICYLSIPNMFTGLECGHKFCSQ CWAEYLTTKIMDEGMGQTISCAAHGCDILVDDQTVMELVTDPKVRLKYQHLITNSFVGCN RLLRWCPMPDCGHAVKVQYYDTKPVTCACGHTFCFACGENWHDPVRCKWLKKWIKKCDDD SETSNWIAANTRECPKCHATIEKDGGCNHMVCKRCKFDFCWVCLGPWEPHGSSWYNCNRY DEDEAKKARDAQGKSRAALQRYLFYCNRYMNHMQSLKFEHKLYASIKIKMEEMQQHNMSW IEVQFLKKAVDVLCQCRQTLMYTYVFAFYLKKNNQSIIFEENQKDLENATEQLSEYLERE ITQEMLADIKQRVQDKYRYCESRRKVLLDHVHEGYEKDLWEYYEMATTDGKMSTTERVVK SVPFPPSHRLTMSEVFDSKGKPKPDALKQHFILEGRVTEDVALRIINEGAALLRQEKTMI DIEAPVTVCGDIHGQFYDLMKLFEVGGSPATTRYLFLGDYVDRGYFSI------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------GFSPR GGGRGGRGGGRGGGDRGGRGGGRGG--GGRGGMRGGKKVSIEPHRHEGVFIARGKEDALV TRNMVPGESVYGEKRISSEDNNKIEYRAWNPFRSKLAAAILGGIEDIHMGPGSKVLYLGA ASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINVAKKRTNIIPIIEDARHPHKYRMLVG MVDTIFADVAQPDQARIVAINAH---------------------------------KLRN EKIKPKEQLTLEPYERDHAVVVGHYRPPTKEMDKNKLNDLAGRLQKGGRGAGIGLGFLAA AGGLAYGLYQSMYTVDGGHRAIIFSRIGGVQDDIYKEGLHFRIPWFHYPIIYDIRARPRK ISSPTGSKDLQMVNISLRVLSRPDQLRLP------------------------------- ---------QVSLLVRKELTDRARDFNIILDDVAITELAFGKEYTAAVESKQVAQQEAQR AQFIVERAKQERQQKVVQAEGEAQAAKMIGEAVALNPGFLKLRK---------------- -----------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXX----VAGGTASVYVGQPLDTVKVKMQTFPTMYRNAVDCFMSTLRNEGARGL YAGTVPSLENAILFMAYGACQKGVA----------------------CGKQLYREGGIRS IYKGTAATLLRDVPASGAYFMSYEWLLHILTPEGGSRSDLSPRTMFAGGMAGIFNWLIGL PPDVLKSRLQTQKEGIFALYKGATPVLLRAFPA--------------------------- ------------------------------------------TNRVINDTVSALRQLSSV GRADRSKRLQYERLTNEFKESVERYSTLQKKQA------------------EQSWKELKT SLDDLNGLMKDFATLVHAQQETVDRIEDNIETSNVQSGVRNLAKAVNFKT---------- -------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXX-----RAQSPKEALVKLRETEEMLTKKSDYLEK KIKDATDAAKKRSAIQALKRKKMYEKNQKQVDETLTTNKYHRIALENANTNTESLRVVG- ------------------------------------------------------------ ----------------------------------XXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXX------------------------------------ --------------------------------------------------------IEAE IGLAVIITEGIPQQDMVKVKNALLKQSKTRVIGPNCPGIIKPGECKIGIMPGHIHKPGRI GIVSRSGTLTYEAVHQTTVAGLGQTLCVGIGGDPFNGTNFVDCLECFLHDPATEGIVLIG EIGGQAEERAAEYLMEHNGPNRKPVAAFIAGLTAPPGRRMGHAGAIISGGKGGAQEKIQT LKNAGVEVTLSPAQMGTTMAKALEEAGKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------- ---------------------------------ISFKQLHLTPFVIISHSARTGTVTKAW MKEKVNEKWEETTWAKKLEARKQRASLSDFDRFKLMKAKQSRNRLINIEFGKLKAAGKKT CPLLLRVFCSTGRHHPLNEYARGNTPANELQIYTWTDASLKELTSLVKEVNGDARKKGTF -------------------------------------------------------XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------------------- ----------------------YKIETKKVSKSIAMRKAWKKFGAATHDPPGPNPANTIE DVYMQFVNATEQ-EEDPLNKLKVSCRICKGDHWTTRCPYKDTLAPIQDALPTTGKYVPPS MRDGGNKRGESMA-DEAATIRVTNLSEDTRESDLQELFRPFGSISRIYLAKDKITGQSKG FAFINFHRREDASRAIAGVSGFGYDHLILNVEWAKPS------FLFKFLVIGSAGTGKSC ILHQFIENKFKQDSNHTIGVEFGSKVVNVGGKSVKLQIWDTAGQERFRSVTRSYYRGAAG ALLVYDITSRENVQXLQNWLTDARTLASPNIVIILVGNKKDLEAEREVTFLEASRFAQEN ELMFLETSA--------------------------------------------------- -------------------------------------------------EDYVKAGCINL DKPANPSSHEVVAWIKRILRVEKTGHSGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYV AIFRLHSAVENEKKIGQAIETLT------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------XXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXMLKPKALTQVLSQANTGGIQSTLLLNNEGALLAFSGYGDKDARVTAAITSNIW AAYEKNGKAAFNEENMKFILMECDEGKVAITRVANLLLCIYAKESVGLGLLKAKAEALAE YLEEPLTQVAAS------------------------------------------------ ------------------------LERDSKIVVPPLPSKAWGRQLPFRGDDGIFEDEFIE DRRKGLEQFVNKVAGHPLAQNERCLHMFLLEPVIDRNYVPGKVRTTXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXMDVFLMIRRKKTSIFMDAKETTSVADLKKAITGISKRNPED MKLFKDNKTLSDCGYTSSIARAQAPATVGLAYREFEELEIAPLSTPPELPDVMKPQESAS SHAQE------------------------------------------------NSPGGVG FGRTPRRPDSMLDMWHPLEKAAYPEYFARREQRKQEFIDAYEKKYGKPE----------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------RVYTHEVVTLWYRAPEVLLGSPRYSTPVDLWSIG CIFAEMVTKRPLFHGDSEIDQLFRIFRTLTTPTEDTWPGVTSLPDYK------------- ------------------------------------------------------------ ------------------------------------------SSPRSVPTVTGSKDLQNV NISLRTIFRPIADRLPLIYTNLGIDYDERIMPSIVNEVLKAVVAQYDASELITQREIVSS QISEELTARAAQFGIVLDDIAITHLTFGREFTEAVELKQVEQQAAERARYIVEKEEQRKI AAVIRAEGDSAAAELLAKAFGDAGEGLVELRKLEASEDIAYQLSQSPNVVYLPSGQQTLL SLPMKTIRSNQTVVIPDGVECLVKARKVTIKGKRGTLRKSFAHLSVDIKKIAKNKILVEK WFGIHKELAAVRTVCSHIENMVKGVTKGYRYKMRSVYAHFPINIAISEGNTKVEIRNFLG EKYTREVSMLTGVTCEASKAQKDEFILEGNDIELVSRSAALIQQSTTVKNKDIRKFLDGV YVSEKGFVEEDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XX---------------------------------------------------------- ----------------------------------YVTDCVMAELEKLGSKYRIALRIAKD PRFVRLPCMHKGTYADDCLVQRVTQHKCYIVGTCDKDLKRRIRKIPGVPIMYLAQHRYSI ERMPDAFGAPKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------- -----------------------------LNQFIAHAALDLVDEQVWTHNNMYLKIVDKF NEWFVSAFVTAGRMRFLMLHDVKNEDGIXNFFQEIYETFVKHSMNPFYEPNTQIKSPAFE KKAQVYGRK----QIRLAHTDVQVPDFSAYRRDSVKTPRRAFTYMMVAGGTIPAAYAAKS LVSEFVSTMSASADVLALAKIEVKLSDIPEGKNATFKWRGKPLFIRHRTAEEIEREAAVD IGSLRHQEHDSERAQNPEWLILLGVCTHLGCVPIANAGDYGGYYCPCHGSHYDASGRIRK GPAPLNLEVPEYTFPDDSTVVVGMSRQATRAVDPRKVSGELFTLTYGSLVAQLLKDYESD DEVNKQLEKMGYNIGVRLIEDFLARSNSGRCHDFRETADVISKVGFKMFLGVVPAVTNWS AAGDEFSLILENTPLTDFVELPDGHSNLNYSNILCGALRGALEMVQMDVGVWFVQDQLKG DNITEIRLRFIKRLEDAVP----ENVKAFLAQAKEDFNXKWEEPSSNTACLDDFDRIKTL GTGSFGRVMLVQHKATKSYYAMKILDKQKVVKLKQVEHTL-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -MFADTLLILFISIATAFLGEGLTWLLVYRTDKYKKLKSEVEKQSKKLEKQKEAIGQTAE RSQKKKLERQEERLKNNNRDLSMVKMKSMFAIGFAFTSLLSMFNSIFDARIVAKLPFTPI SWIQGISHRNLIGEDYTDCSFIFLYILCTMSIRQNIQKLLGFAPSRAASKQGGGFFSTCV KYFDRWSEIEQVVFRRXLLSRMCHYQHGQINTYLKPMLQRDFISALPAKGLEHIAENILS FLDDKPTVAAELVXKEWLRVISDGMLWKKXIRKWVLTDPLWKGLSERRGWGQHLFRPKAG ESPKDSKFYHRLYPNIIQDIE--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXX-------------------------------------- ------------------------------------------------------------ --------KKVNIDFEPFRPINTSLYLCDNKFHTEALTALLADDNKFGFIVMDGNGALFG TLSGNTREVLHKFTVDLPKXHGRGGQSALRFARLRMEKRHNYVRKVAEVAVQLFISNDRP NIAGLVLAGSADFKTELSQSDMFDPRLQAKIIKIVDVSYGGENGFNQAIELAAEALSNVK FIQETRRV---------------------------------------------------- -------KPEQEKDKTYFTDKETGVELELVDSMPLLEWFANNYKSFGATLEIITDRSQEG AQFVKGFGGIGGILRYQVDFQTLEPLDDLG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------QHSDADRSPVFXQFID CVWQMTXQFPNAFEFNEXFLITILDHLYSCLFGTFCXNTDQQRAKEEVRTKTVSLWSYTN SQIEEFTNPLYTHVLFPVASMRCIELWTGLE-AWSASLK--------------------- -------------SPFKPFIPHLPFDLIQCESAFPNSKPAPDEKNFADALLKRAQDLTPA AQEQTAVLNLVTKITSVLDNLVVAPGNFDAAQLDEVRQVGSHKKGTMMAGHNVADIVVIF KTL--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ KGQTKERRRAAIATALAGEVNVVPSARLLALLGQALKWQQHQGLLPPGTTIDVFRGKAAV KEQEEEKYPTQLNRTIKFGQKAHIECAQFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLK YQAQDNFMMMDDAVLCLCFSRDSEMLATGGQDGKVKVWKIQTGQVLRRFERAHTKG---- ------------------------------------------------------------ ----------------LGGTATTDITVHSVHPLPRNVEQFAVCNRSNTVVIMNMQGQIVR SFSSGKREGGDFVACTLSPRGEWIYCVGEDLVLYCFSITTGKLERTLNVHEKDVIGIIHH PHQNVIA-----------------------------PKFATFMKYAKVELRPPSDFGEAS KSLNKLIAFRTQRWKQVTMKEGTLVTIEVACWFFIGEVIGKRSLVGYQVTGGTHFD---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------GEMDYKTYLDFVLALENRKEAQALQYLFRLLDVQ NKGHLNIFDLNYFFRAIQEQMRMHGQEPVSFDDVKNEIFDMVKPADPLKITLQDLIK--- ---------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXELSPPKTTPEWVNFCKQMFGGFSAAVDWSLSFCFVAYSIQATTYEDPPGDNLYLG IVLTAVVVVTGCFSYYQEAKSSRIMESFKSMVPQFAXVVRKGQKLTVXAEELVVGDVIEV KFGDRVPADIRVVSAHGFKVDNSSLTGESEPQTRTADFTHENPL---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------MTFGLFFETSLAAFLAYCPGLDKG LRMYPMRWTWWIAPMPFSLAIFIYDECRKYILRRNPGGWVEQETYYSFKALPRTKKVLVG ATAGVVGVGAALNELELHPPKYPWSHSGMFDSLDHASVRRGYQVYKQVCAACHSMEYMYY RNLVGTIMTEAEAKAEAEEILVKDGPDEEGNMFDRPGKLSDKFPAPYANDEQAKAANNGA LPPDLTFIVNARHGGEDYLL---------------------------------------- ------------------------------------------------------------ ------WIRPDQLSRCTYQVGIIKDSPHKHKKRPPKILPNILYKIGETPLVKINKIGKSA GLECEFLAKCEFFNAGGSVKDRIALRMIEDAEEKGLLVPGETLIEPTSGNTGIGLALSAA VKGYKCIIVMPEKMSLEKVDVLRALGAEIVRTPTSASFDSPESHIGVASRLLEEIPHSHI LDQYRNPGNPLSHYDGTAEEILRXXDGQVDMVVCGAGT---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------YEGERNERDERHGHGKATLPNGDTYEGQYENGKRNGHGTYRFKNGARYIG EWSKNKKHGQGTFIYPDGSKYEGSWVDDQRSGFGKYYYVNGDTYEGEWQNHVRHGQGTYM YAETGTKYVGTWKDGKREGHGELIHANHKYNGPFKEDRPEGKGKYVFDIGCQQHGEYIXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------TGEH-ALLKMFLNLLSTRLLTEPAEFQIDDTFSVPGVGTVVXGTTLKGHI RLNDTLLLGPDPLGQFLPIVIKSIHRKRMPVKEVRGGQTASFALKKSQIRKGMVMVSPRL EPTACWEFEGEILVLHHPTTISVKYQAV-------------------------------- ------------------------------------------------REKISQKDDHHF YLFKVLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASGEELHTLEGHRNVVYAIAX NNPYGDKIATGSFDKTCKLWSSETGKCYHTFRGHTAENVXLSFNPQKCKPTGSMDSTAKL WDL--TLQGHFGEVTSVKWNDVKEKWVTGSEDGTIRIWSNECEQVLAAQGSVTSLGIDLL NGAIIAGVQD------------------------------------------RVYEAEQY QTNFGHKDSVRSIIHIPERNQYVTASWDRTIRIWNA------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------LTLSFVNPRMLDDVSF HPCVRFKRWESEKILSFVPPDGNFRLISYHIGSQNMVAIPVYVRHSISFKEGSSGRLDIT IGPKQTMGKPVENAVIEVPFPKTVLNVTLTPTQGKYSFDPVTKLMSWDVGKIDPAKLPSL R----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ISYKPDPCRVPKGSTTPQQWEDFSRYNKERAEAEMGNSR RLREAIHQTLQQTDNDLESQKTATDYALRKRIHEFEKAIDELNWQKAQTEEEIAEMEEDI RRLNDAIRAKINPMKLAQTRLENRTYRPNQELCRDNPQYGLTDEVKQLEATKKALEEKLK QAQHALDGLEQNLHRINNDLQCKTNSLKLDQQCEKSRAKLERNVTLTGI----------- -----------------------------GMRGIKGLVTETSVLDPEEGIRFRGYSIPEC QXLLPAAAGMEEPLPEGLFWLLATGEVPTKEQVAAVSKEWANRADIPSHVVTMLNNFP-- ----------------------------HKTTYWEHVYEDSMDLIAKLPTIAAIIYRNLY RDGTSVGAIDPDKDWSANFVSMLGYEDTNFTDLMRLYLTIHSDHEGGNVSAHTCHLVGSA LSDPYLSFGAGMCGLAGPLHGLANQEVLVFXTKVAYTEQGLKEYVWNHLKSGQVVPGYG- -------------------------LFKLVSDLYKTCSRHLLEQGKART-MANVDAHSGV LLQYYGMTEMNYYTVLFGVSRALGCLSSLIWDRALGLPIERPKSMSTEGLVKLVSXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXDKLFVHRDTPXNNPDVPFEFTPENLKRAEAIXRNYPKGHQSAAVMPLLDIA QRQFGWLPISAMHYVADFLKMPRMRVYEVATFYTMYNRDPIGKYHVQICTTTPCMLGGMG SDVILEAIKTNLGIEVGETTKDNLFTLSEVECLGACVN---------------------- ------------------------------------------------XXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSESRWLEYNGPDQSMKYPMKE ACDDWPVEYLEFYPNQEKAKKWMADNLTDEMKDMFLKRQTRGGKGVIKTKAKXEEKKVSL SRSSRGKKKF-------------------------------------------------- ---------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXX------------------------------------- ----------------------------------SGVILFHETFYQKADDGTPFTKMLMD NGIIPGIKVDKGVVPLAGTEGECTTQGLDGLAERCAEYKRDGAGFCKWRCVLKIQSHTPS LQAMLENANVLARYASICQQNGLVPIVEPEVLPDGDHDLETAQRVTEQVLAFVYKALADH HVFLEGTLLKPNMVTAGQSCPAKFTPAQVAIATVQALSRTVPAAVPGITFLSGGQSEEDA TIHLNAINNRPWXLTFSYGRALQASVLQAWQGKAENVGAAQKELLKRAKANGEAAEGKYT GGVEGAGQQSLFVADHAY------------------------------------------ -----------------------------------------------GVPEFWLTIFKNV DMLADMLQDHDEPILKSLHDIKVNFSMGFTLEFYFEPNEYFTNSVLTKEYIMRSEPDETE PFGFEGPEIIKCKGCTVDWKKGKNVTVKVIKKTQKH------------------------ ------------------------------------------------------------ ---------------------------TTLGPRGMDKLIVDNNGKATISNDGATIMKLLD VVHPAAKTLVDIAKSQDAEVGDGTTSVVLLAGEFLKQCKPFVEEGVHPQVIVKAYRRASG LAVQKIREIAVTIKRDPKEQRELLIKCAATALSSKLVARQKDFFSKMVVDAVMSLDELLP LNMIGMKKVQGGALEDSMLVSGVAFKKTFSYAGFEMQPKKYQNPKIALLNIELELKAEKD NAEIRVDNVEEYQAVVDAEWTILYDKLEKICQSGAKVVLSKLPIGDVATQFFADRDMFCA GRVPDEDLKRTMHACGGSIQTTVASLTLGTCESFEESQIGGERFNFFKGCPKARTCTIIM RGGAEQFMEETERSLHDAIMITRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIAGKEQLL IGAMAKALEVIPSQLCDNAGFDATNILNKLRQKHAGMWYGVDVTTEDISDNFEACVWEPA VVKINALTAASEAACLILSVDETIKNPKAHHDPGGRGRGRGRPM--NNMIPNAHFHKDWQ RWVKTWFNQPARKQRRRNNRIKKAAAVMPRPVAGDLRPVVRCPTLKYNRRVRAGRGFTLD ELKGAGINKRVARTIGIAVDYRRRNGSVEGLQQNIQRLKEYRSKLIVFPKKAGKPKKGDA TEEEIKMATQLTGAVMPVQQFHKKEKARKITEEEKNYQAFQVLRKARANKKLQGLREKKA REAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXLSCRFYEHKFPEIEDVVMVNVRSIAEMGAYVHLLEYNNIEG MILLSELSRRRIRSINKLIRVGRSECVVVIRVDKDKGYIDLSKRRVSPEEIXKCEEKFAK AKXVNSILRHVGELLK--------------------------SAYEAFKMAVTNPEILEE CGLDDETKRVLVNNIKRRLTPQAVKIRADVEVSCFAYEGVDAVKNSLKAGLNLSTEDMPI KINLIAPPLYVVTTTTLERSDGMARGQQKIQSQQKAAEKAAKLKHDQKKAAAAALTYQCP VCKTKMGDPKTFKQHFENKHPKSPLPEELKDVXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------X KLSKYIGENIRLLIDRPDGTYCFRYHKDRVYYVSEEIMKKAGNIARENLISFGTCIGKFT KSXKFRLQITALDYLAPYAKYKVWVKPSAEQQFLYGHHIMKSGLGRITENTSTYQG---- ------------------------------------------------------------ -----IDGLVQMLNEGNPNTDVVVAPPSIYMDYVRQKLIGVAAQNCYKAEKGAFTGDISP AMIKDVGCEWVVLGHSER------------------------------------------ -------------------------------------------------NVSPEVAKSVR ILYGGSVTAANCKELAQQPDIDGFLVGGASLKPDFITIINAKEREGLLDPAWEKQQKKTF TAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGEQLPKPDRGKMRFHKIANVNKAL EFIESKGVKLVSIGAEEIVDGNLKMTLGMIWTIIVQNFHLSFKDGLAFCALIHRHRPELL DYHKLSRDNPLENLNLAFDVAEXHLDIPKMLDAEDMVNSVKPDERSVMAYVSSYYHAFSG AQQAETAANRICKVLKINQENERLMEEYERLASDLLEWIRRTTPWLENRTTDNTLPGTQR KLEEFRDYRRQHKPPKLEQKAKLETVFNTLQTRLRLSNRP----------SDIANAWKGL ERAEKGFEEWLLSELQRLERLDHLAQKFKHKCDIHEEWSYGKEDMLQAQDFKKCRLNELK AMKKKHEAFESDLAAH-------------------------------------------- -----LEEAEHILERIDQLHLEFAKRAAPFNNWMDGAKEDLIDMFIVHTTEEIQGLIDAH EQFKMTLGEADKEFNAIIGLVQEV---------------------------KWKDVKQLV PQRDSTLQAEMIRQQNXERLRRQFAQKANVVGQWIERHLDAVASVGVQKGSLEDHLNKLR GIEKEVYAFRPNIEELERYNQEVQEAMIFENRHTPYTMETLRVGWEQLLTSVARNINEVE NQILTRDSKGISNEQMEEFRKSFFHFDKTRKRRLEPKEFKACLISLGYNIRDDRQGEADF QRIMSIVDPNGLNYVTFDSFLDFMTRETTDTDTAEQVMQSFRILAGDKSYITADILRREL PPDQAEYCIQRMAPYTGRDAVPGALDYSSFSTALYGESDL-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AEDANVGMASVSTGVPDGCMGLDVGPESITKFT EVVGRAKTIVWNGPPGVFEFPNFAKGTKGMMDAVVHATEKGATSIIGGGDTATCCAKFGT EEKVSHVSTGGGASLELLEGKNLPGVAALSDAMAGIPPKSWQPANVTIETTIGNVVCELY WRHAPNTCRNFAELARRGYYNGVKFHRIIKDFMIQGGDPTATGRGGASIYGKHFEDEIHI DLKHTGAGILSMANSGPNTNGSQFFITLAPTQWLDGKHAIFGRVSNGISVVQRMGM---- ------------------------------------------------------------ ---------------------------------------LAQAEGNPVIACQVNLDKNFA FLEFRSVDEATQAMAFDGIDFQGQSLKIRRPRDYQPLPGMAETPSVGVVSTVVQDSPHKI FVGGLPNYLNEDQVKE-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRLKGQIPDIRSSL NIVQHMKSKKEPLKTHFQLSDNLYAKATIPPTDNVSLWLGANVMLEYTIDDAETLLTKNA AVKSLEQVEEDLGFLRDQTTTIEVNMARVYNWDVKRRQ-------EALARAGLHFDELNK IRVLEPEISSQTGELKEECKEFLDKMQEFKKIVGTFISLIDEVSKEVXKRKMKAIGSRNL LKSVAKQREAQQQQLQALIAEKKMQLERLRIQHDSLAREEQEQNDFIEQFILQK------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------EKALEQLNGF ELAGRPMKXGHVTERTADASLLDSDEMDRAGVDLGATGRLQLMAKLAEGTGFQIPQVAAN ALSMAPTNQTPPIATQCFMLSNMFDPSTTTANWDVEIRDDVIEECNKHGGVLHIYVDKAS PQGNVYVKCPSIAAAVASVNALHGRYFAGK------------------------------ ------------------------------------------------------------ ------------------------------------------------FVNNEHVSTIGE GGSFGELALIYGTPRAATVKAKVDVKLWGIDRDSYRRILMGSTIRKRKMYD--------- ---------------XPVQFEDGVEIVRQGEPGEEFFIITEGAASVLQRRSENEEPVEVG KLGPSDYFGEIALLLDRPRAATVVARGVLKCVKLDRGRFERVLGPCSDIL---------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -KLFLELEPQLRDILHQFYESKYATCLKLLDEIKDNLLLDMYLAPHVNTLYVKIRNRALC QYFSPYLSADMNKMAVAFNTSVSALEDELMQLILDGQINARIDSHNKILYAKDIDQRSTT FEK--------------------------------------------------XXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXRHTVTLLSGDGVGPEMLGHVREVFRYAGVPVDFEEVE LNRNGVALKGNIYNKFRSRNIEIRDELELLTNIVHCKTIPGVPARHSDVDLVIIRENSEG EYANLEH----------------------------------------------------- ------------------------------------------------------------ ----------------EARHAHAGQAGKNLANPTAILLCAANMLKHMNLDHHGKLIQDAV EKTIKAGKVRTPDMGGYGTRSDFTMEVIKNLSEDFNKFMDRSSRLVERAIYEDVDIFAEY TGDESEDGLAEGEKLKLGRQFFDERWSKYRTVTCMDWSTQYPELLVASYNNNEEAPHEPD GVALVWNIKYKKPSPEYIFHCQSSLMSVCFAKFHPNLIIGGTYSGQIVLWDNRSNKRTPV QRTP-------------------------------------------------------- ------------------------------------------------------------ -----------------------------EDNSDYIYDAKWSPLHPALFATVDGMGRLDL WNLNHDTEVPTASVTAVALNKCRWHQSGHNIAVGDDLGKIYLYDVGEPLAVPRNDEWPRF VHTLQELKNNQADNDEDA------------EQQVDAELARLDKMDEDDFEVIRQKRXLQL KKAQQQKIQWQQLGHGKYEEIADEREFFDVCKKSKNVVCHFYRDATFRCKIVDKHLAVLA PKHLETRFVRIDAEKCKFLVERLRIVVLPTIXWPRYGKTVDYVVGFDDLGRRDEFPTEXV EWRIARADVIHYNG----------------------KTLVLTGHGGYDKMNVEERPKPAR GEVLVNIRATGINFAELMCRQGMYDRSPKLPAVLGLEGAGEVVQLGDGCDRVKLGQRVIC MSGLW---------------------------------------------------GGVG IAATQLCKTVDDVTVFGTSSAKHDVIRSYGVTHPIDYRTKDYAEEIRKV----------- ------------------------------------------------------------ -----------ESILHHFVTGELKTIIDSTFPLEEIGDAHKMMEENRNAGKIVIE----- RKQTPSDFLKQIIGRPVVVKLNSGVDYRGVLACLDGYMNIALEQTEEYVNGQLKNKYGGV Y----------------------------------------------------------- ------------------------------------------------------------ --------------------------------PPTXDAAKNFRENYEEYRQRVKKLVRKS VE-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXX---------------------------------- ------------------------------------------------------------ ------------------------------------------------QLPANRFLQPVH KCDMALTDLLGELQRDPWPVAQGKRPLRSTGVALSIAVGLLECTFPNTGARVMLFAGGAC TQGPGMVVGDELKHPIRSHHDIEKDNCKYMKKA--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------VLTDDVSLQVFMEHLKKLAVSSASMSTLTQEQQLKLI SDLEIEMMADMYNRMTTACQKKCVPPKYKDTELNKGEAVCLDRCVAKYMDIHERIRKKLT AMSVQDEETMRKMQAAQQPAVIHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYR KKVVLDGEEVQIDILDDYAAIRDNYFRSGEGFLCVFSITEPESFQATSEFREQILRVKND ENIPFLLVGNKMDLEDRRQVTVEEASAKSQQWNVSYVETSAKTRANVDKVFFDLMRLIRT KKQF-------------------------------------------------------- ---------------------------LMIFRDQVTRYPVIRNHLRDTLLDMVAKERRGE VVDRGAVKNACQMLMILGIDSRSVYEEDFEKPFLDQSADFYRLESQKFLGENSASVYIKK VEARINEEAERATHYLDKSTEEPIVKVLEEELISKHMKTIVDMENSGVVHMLKNNKTEDL GCMYKLFIRVLNGL---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------SKGPRKHIIQVSTYQMVILMLFNH RDKWSYEEIKSETDIPERDLMRAIQSLALGKITQRVLSKEPKTKEIEPNHLFMVNDQFTS KLYRVKIQTVAAKGESEPERKETRNKVDEDRKHE-------------------------- ----------------------------------------XXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXX------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------QDVTNVIIWGNHSSTQFPDVRHAQVVPAAVQDDNWLKNEFISTVQKRGAA VIAARKLSSAMSAAKAICDHLRSWWTGTPQGQWVSMGVPSDGYGIEKGLIYSFPVSIDHS YSIVQGLEIDDFAREKMDITMKELKEERDDALETCXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXMTTLRPFTCDDMFRFNNVNLDPLTETYGLPFYMQYLAHWPEY FQVAESPSGEIMGYVMGKAEGHADNWHGHVTALTVAPEFRRLGLAAKLMNILEDISEKKE CFFVDLFVRVSNKVAVDMYQQLGYSVYRRVLEYYSGEQDEDAFDMRKALSRDVDGKSVIP LEHPVRPEEL-------------------------------------------------- ------------------------------------------------------------ ---------------------------------------HVVEVQEKSSGRSAHYKLTST AMLWLQTNKSASGTMNLGGSLTRQVEADSNVSESSPHIANIGRMTRRV------------ -----DIVNGLRSVQPLLQDALRNDLAAALKNRS-------------------------- ---RVDPEKRMTTAYMTKYERARVLGTRALQIAMCAPVMVELEGETDPLEIAMKELKARK IPIIIRRYLPDGSYEDWGIDELIIAD---------------------------------- -LCYYGLGMSNQVGAIDRATVWPDVVKARIRDTYAYFGSSLIFTAVSRSPAIMNLMMRSS WLALFGTVAAVIGTGALVRSIPYKEGAKQLAWMLHAGVLGAVIAPITLLGGPIMIRAACY TAGIVGGLSTVAMCAPSEKFLNMGGPLAMGLGVVFMASIGSAFLPPTTALGAGLYSISLY GGLVLFGMFVLYDTQKIIKRAETHPLYGVQPYDPINNSVGIYLDTINIFMRMAMILAGGG NRKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------Y MMSIRDFKSAAKLFLDTVATFTSYELMDYKTFVTYTVLCGIIALDRPDLRQKVIKGSEIL EVLHSLPEIRQYLFSLYNCQYGDFFKSLASVEQKMKYDRYLAPHYRYYTREMRIHAYSQL LESYRSLTLDYMAKAFGVSPQFIDQELSRFIAAGRLHCKIDKVGGIVETNRPDSKNYQYQ ETIKKGDILLNRIQKLSRVINI-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------GAAAVVTC VANFMAEFPHFADNPAVNVTKAAQFLGTYIGGVTFTGSLIAFGKLQGLLKSDPLMLPGRH MMNAGLMLANVGAMGWFMMDDTNIGMSMLGTTALLSSVMGVTLTMAIGGADMPVVITVLN SYSGWALCAEGFMLDNNLMTIVGALIGSSGAILSYIMCKAMNRSLPMLSLXGYGTSSYAA XKAMEIXGTHTEILSDGTVELLAEAQNIMIVPGYGLCVAKAQYPIAELVELLRKKGKNVR FGIHPVAGRMPGQLNVLLAEAGVPYDIVHEMDEINDDMPEVDLTLVIGANDTVNSAAEED PNSIIAGMPVIRVWLSKQVIVMKRTLGVGYAAVDNPIFFKENTSMLLGDAKKTCDALLAG AKMSTPETSSNCPPGLEYLLKVDQLLVQQQVEVLEAFTGFETNNKYEIKNSLGQRVYFAA EDTCCCTRNCCGHKRPFEIKIHDNSGKEVIRLDAPLRC--DTCWFPCCLKKVTVQAPHGT VIGHVRQAVCKPKFCINNAVLIVEGPCITCN--IC-GDVEFQVLSHHIGQIRKQWT---- --FTDADNFGITFPMDLDVNIKATLLGAIFLIDLMFFEKE----DAELQQFMAMESQKAQ FQSQVHKLTDVCWDRCMDKPRDKLDYKTETCMTNCAERFIDVTLTITTRFQQMLQKQL-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------MKRVRELLDLD FEQESMKDGANELMWAVITAFSK------------------------------------- ------------------------------------------------------------ --------------ELKNILSDWNEKCKGCTEKSDYIKMIEDKIDKTRTEA-PEDILKGF KLNWMNLRDADSGKVLWQSSDDLSSPEVEHEARVPKKILKCRSVAREINFSSKETMERFR LEQRVMFKGKCLEEWYFEFGFVIPDSTNTWQSIIEAAPENQMMPANVLNGNVMIETKFFD GDLLVSTSKVRVFYVMPKVVSRSVVCTDTKDQEEYQGEKPLHVYYCLCGQMSLILDCAIE KLPKRRRDDAMVIDSNKHAHKITAEPDETVHIKRPEGIERQYRQKCKKC---------NI ITFIVDGALKKQGEKGPTLYNQVAEPKKVMVKKHTKNMGKFSSVTVSTVDEEEDEIEAKE IADSYAANARVIEKQLIRKGLSKRKLLEEAELEAKRMRPKGTLIDXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXCKNFITELKERLDRSARSKEIIETGHGLDRKKRFKYLTSELRLTEALHEPHIC ENIRQYNVHAERKGSNRHAKGMSETFQTLHGLVDKGVKVDLGIPYELWDTPSAEIIKMER ACYTLAERMEDDIEEWYYNNQEDILNFICRDRVLK----VFSATDVTSADDVSNAITARE KFGKLDVAVNCAGIGVAIQTFNPKKDKVHSQDDFMKVLSVNTEST--------------- ----------------------------------LVGMTLPIARDLSKIGIRVNTIAPGL FDTPLLASLPEKVRTFLASTVPFPAKLGHPDEYAHLVQAIVENPMMNGECIRLDGALR-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------VIQNDGQDRVVPGLYAAGEAACVSVHGANRLGAN SLLDLVVFGRACANTVAETHKPGQAVPTISDSAGESTVALIDGFRFANGATPTADLRLRM QKVMQNNAAVFRDGPTLEEGCQKLDALYKEMDIKVSDRGMIWNTDLIETIELQNLMLNAL QTIYAAENRKESRGAHSREDFPDRIDEMDYSKSTEGQNXKPIDQHWRKHTMSYCD----- ----------------------------MTALSQEDIISNTKTVVQGLDTLKNEHHQILN SLLSSMKTIKQGDTNLVEEKTNILKKSLEMIELGLGESQVMMALANHLQYVEAGKYK--- -------------SALENLEKAL------------------------------------- ------------------------------------------------------------ --------------------------------DVATKVFGNEHIQVAVLHNDIATMSSYN GKLSKAKDHSKRSIVIGEKLEAKELP---------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------EKNIREFTEEQLKAGQLQAGTNKCA SQSMGGVRHVADIKADDMDKAGASIISGQMGAKGASQAGMSMGGARHAADIRADDMDKAG ANVIGLQAGSNKGASQAGMSMGGARHAADIRADDLDKTGTSIIGGQMGYTGGASQAGMSM GGARHAADIRADDMDTGASVIGGQMGYTGGASQSGMSMGGARHAGDIQAGQMQGQSVIGL QMGSNKGASQSGMSMGGARHAGDIQAGQMDSQGVINLQAGSNQGASQSGMSYGGRRDVMA ETHSFGTVPITCHAWNSDRSQMAIPNNHEVHIYKNQWTKVEVLDEHVQRVTGIDWAAKSN QLVTCSADRNAYVWPALVILRINRAATCVSWSPLENKFAVGSGARLISVCYFEVENDWWV SK-----------------------------------AMMKEVEGKPEATPWGKKMTFGN LMAEFSNGGGWVHSVSFSASGDRLAWVGHDSSVSVVEAFIKTHFLPFVSCTWVNEANLVV AGHDCCPMLFCYENGKVAFARKLEETKFSAMNHFRSLASRGQTLETTHQNTITWVAIHTG NKQRVTRFSTTGVDGQLAIWN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------TLTPDECREFKKTIXNEIAQHKIRIYEFDDEEENRVLKKLKDRV PYAVIGSNTVVESGGRKVRGRVYPWGIVEVENLEHNDFIALRNMLIRTHMQDLKDVTNNV HYENFRYNKLASVTKSPLLQMEEEKKEHVQKMKXMEAEMEQVFEMKVKEKRTE------- --------------------------------------XXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------QKKN SLLEADVSSRQDRLDHITSAAAKFTETGHFXADNIQKKQVTLVERYRSLQDPIKNRQTKL GDXLRLQQFFRDVEDEEDWIREKEPIAASTNRGRDLIGVQNLMKKQQALQAELAGHESRI TSVTQTGEQMVADGHFASDDIQNKIQGLNDRWQLXVDKSAQRSQDLEDSLQAQQYFADAN EAESWMREKEPIVGNTDYGKGEDSAEALLKKHEALMSDLEAYRSVIDGLREQAQACKQQE APVIDDIGKECVVALYDYQEKSP------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----VAQQWDQLDQLGMRMQHNLEQQIQACNQSGVSEDALREFSMMFKHFDKDKSGKLN HQEFKSCLRALGYDLPMVEEGQRDPEFEAILD---------------------------- ------------------------------------------------------------ --------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIDKDDKDNPQ LVSEYVNDIYEYMRQLERGEINGRMRGILVDWLVQVHLRFHLLQETLYLTVAIIDRFLQL EVSRSKLQLVGVTAMLLASKYEEMYAPEIADFVYITDNAYTKSDIRKMECIILKTLDFNL GRPLPLHFLRRNSKAGEVDANKHTLAKYLMELTIVDYDMVHYYPSQIASAALSLSMKLMD WNDTLEFYSKYSESELMPIMKKMALLVTKKLVAIKTKYQSSKFMRISTIPELKSKVIQDL AXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------VQGYALNCTVASQLMVKKITNAKIACLDFSLQKAKMKMG VQVLVEDPTKLDAIREREFGITQERIQKIMATGANVILTTGGIDDLCLKYFLEAGAMAVR RCKKQDLKRIAKATGGQLVSTLANLEGEETFEAAMLGAADEVVQDRICDDELILIKGTKA RSCSSIILRGANDFMCDEMERSVHDALCVVKRVLESKSVVPEGXAVEAALSIYLENFATS LSSREQLAIAEFAKSLLVXPKQLSVNAATDSTDLVAKLRAYHNKSQTSAEHKDLKWVGLD LHEGVVRDNKKAGVFEPAISKIKSLKFATEAAITILRIDDMIKLAPEQKGGPSYQDALRA GTLDDEGARLLASKSILNEMLVEGKDLTVEYTIFNVGGSAALDVELSDASFPDSDFE--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---DEDPVQAEAYINRASLLQADSTNEELQIYYKVCYARVLDYRRKFIEAAQRYNELSYK SIVDESERMQALKNALIGTILASAGQQRSRLLATLFKDERCQQLPAYGILEXMYLDRIIR SSELADFSGLLQPHQKAVTSDGSTILDRAVIEHNLLSASKLYNNIXFDELGSLLEIPPLK AEKIASQMITEGQ----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---IYDLRSFDKGPFATFKLQQDKDCDWTGLKFSPDGKLILISTNGQVVRLIDAFQGTPL QTFMGHQNXKGIALEASFSPDSQFVFSGSTDGKIHAWNTETGAKVVVLNGDHTGPVQCVQ FNPKYMMLSTACNNMAVWLPQVDE------------NVGLITLDRPKALNALFNPLMAXL SQALDEFEADDSVGCLVLTGSEKAFAAGADIKQMQNKTFTEVYKQNFLSHWNRLQYTKKP IIAAVNGFALGGGCEVAMMCDIIYAGEKAFFGQPEITIGTIPGAGGTQRLTQAIGKSKTM EMV-----------EKAGLVSKVYPPNQVVDEAIKTAEKISSHSKIVVQMAKEAVNASYE MTLEEGLKFEKRLFHQTFATKDRLEGMTAFVEKRAPNFVD >Owenia_fusiformis_FR MTERKAVIKNADMSEDMQQDAVDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSG-----RCFQTSATQRDIDQAAKFIGAGAATV GAAGSGAGIGSVFGSLVIGYARNPSLKQQLFSYCILGFALSEAMGLFCLMMAFLILFAFM SHYKETGKAPEATIHRIRITLTSRNVKSLEKVCADLIHGAKEKNLKVKGPVRMPTKTLRI TTRKTPCGEGSKTWDRYQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XMATQISKKRKFVADGVFKAELNEFLTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVL GEKGRRIRELTSVVQKRFNFPEGTVELYAEKVATRGLCAIAQCESLRYKLIGGLAVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPINDYVDTAVRHVLLRQ GVLGIKVKIMLPWDPNGKIGPKRPLPDHVSIVEPKEEEIPTTPISEQKGGKLSKRGRGGT SGGKFRISLALPVGAVINCADNTGAKNLYIIAVHGIKGRLNRLPAAGQGDMVMATVKKGK PELRKKIMPAVVVRQRKAIRRKDGSFIYFEDNAGVIVNNKGEMKGSAITGPVAKECADLW PRIASNAGSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGKPRGIQTARKLRTHRRLQKWHDLG YKKSHLGTRWKANPFSGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP NDGCLNYIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKEKKERPRSXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPRI PLVMGKTYTTPRRPFEKERLDQELKLIGEYGLRNKREVWRIKYALAKIRKAARELLTLEE KDPRRLFEGNALLRRLVRIGVLDEGKMKLDYVLGLRLEDFLERRLQTQVFK--------- ---------XXVRKQVVNIPSFVVRLDSQKHIDFTMTSPIVGGRPGRVKRKNMKKGNKGG DDMGGAFGSLFKSLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAKEELNRMLNEDELRD AVLLVFANKQDLPNAMNAAEITDKLGLHQLRNRSWYIQATCATSGDGLYEGLDWLSNTLK ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRMHAPGKGISQSALPYRRSVP TWLKLTSEDVKEQIYKLSKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKAKGMAPE IPEDLYHLIKKAVAMRKHLERNRKDRDSKFRLILVESRIHRLARYYKKKRVLPPTWKYES STASALVAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXX--EQMTLRGTLQGHEGWVTQIATSAQCPDMILSASRDH SLIMWKLTRDTNYGVPQKCLKGHNHFVSDVVMSSDGQFALSGSWDNTLRLWDLSTGLTTR RFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIDESHSEWVSCVRFSPNT IVPVIVSCGWDK---------------------------------XXXXGGKDGLAILWD LNEGKHLYTLDGGNEINALTFSPNRYWLCAASGSSIKVWDLEGKTVVDELKHEVISTAV- APQCTSLAWSADGQTLF------------------------------------------- ------YDPTIEDSYRKQVEVDGNQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTFNDLHDLREQILRIKDTEDVPMILVGNKCDLEDERVVGKIGRQWNCAFLETSAKSK VNVNEIFHDLVRQINKKNPETXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------------- ------------------------------------------------------------ ----SLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDENTKRELMKMKQEPVRPEDARV MSDKIDAFAYLECSAKTKDGVREVFETATRAALQVKKKTKAKMDDFQSAEEAAFVVDEVS NIIKESIESAIGGNAYQHNKVNQWTSNVVEQCLNQLTKLGKPFKYI-------------- -------XXXTDGSCTVRWENKTMYCIVSVFGLSIMFSVSAKILKPGGEKPDEFESSISQ ALLDLEMNSDLKAQLRELNITGAKEIDVQGKKAIIIFVPVPQLRLYQKIQTRLVRELEKK FSGKHVVFIAQRR------------------------------------XXXXXXKRIRI KLDGSRTIKAHLDKTQQTNIEHKVDTFTAVYKKLTGKDVVFEFPENLLXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSGGLSA LTLKEEDVTKFLACGTHLGATNCDFQMESYVFKRKPDGVFIINVRKTWEKLLLAARAIAA IENPADVCIISARPYGQRAVLKFAHYTGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDP RTDHQPLTEASYVNIPVVALCNTDSPLRHVDVAIPCNNKGSHSIGLMWYLLAREVLRLRG TISREVPWDVMVDLFFYRDPEEVEKDQEVTDWASEAVVPSVPIQTDEWAAPEPSDWAAPT T--------FNKMVSGSRSKNRKRHFNAPSHIRRKIMSSPLSKDLRAKYNVRSIPIRKDD EVQVVRGHYKGPQYGKVVQVYRKKFVIHIERIQREKANGASVNVGIHPSKVVIVKLKLDK DRKSILERKSRSRQVGKHTEETIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXSTNKEFLMNGKYKLIRKIGSGSFGDIYLGINI SNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGEKDYNVLVMDLLGPSLE DLFNFCSRRFTMKTVLMLADQMIGRIEYVHNKNFIHRDIKPDNFLMGIGRHCNKVFLIDF GLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRGS LPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLR QLFRILFRTLNHQYDYTFDWTMLKQKAAAA-----------------------HRTATTD DKKLQSSLKKLAVNSIPGIEEVNMIKEDGQVIHFTNPKVQASLAANTFAITGHGEIKQMT EMLPGILNQLGAESLANLKKLATATEEIDDDDDEVPDLVENFDEASKEEMTRYSLDPQNA TKSAKAKGSHLRVHFKNTRETAQTIKKMHLRRAVRFLKNVVGHTECVPFRRYNGGVGRCA QAKQHKTTQGRWPKKSAEFLLQLLKNAESNAEYKGLDTDHLVVEHIQVNRAPNMRRRTYR AHGRINPYMSSPCHIEVILAEKEGAVAKPTKKKVSQKKLKKQKMMMRD-------ELGEE QKQEIKEAFELFDTDKDRAIDYHELKVAMRALGFEVKKADVLKVLRDYDREGTGKISFED FNEVMTDMMLERDPQEEVAKAFKLFDDDETGKISLRNLRRVARDLGENMTDEELRAFDRD GDGEINGDEFISIM------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSLVIPEKFQHIL RIQNTNIDGRRKTPFAMTAIKGIGRRYAFIVLKKADIDPFKRAGELSDEEVEKIQTVMMN PRQYKIPDWFLNRQRDVKDGKTGQVLSNALDNKLREDLERLKKIRAHRGLRHYWGLRVRG QHTKTTGRRGRTVGVSKKK-SGTESDSDDSMPDLEEVAAAAGITEEMVSKAKQSRSEKKS RKAMSKLGLKQVTGVSRVTIRKSKNILFVISRPDVFKSPASDTYIVFGEAKIEDLAQQAQ MAAAEKFKTEEEIDEGGVEGKDIELVMSQANVSRGKAVKALKNNDNDIVNAIMXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGIKFLEFVKPFCAVLPEIQKP ERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVIMASNRGTLMELGIS PIVTSGLIMQLLAGAKIIEVGDSPKDRALFNGAQKLFGMVITIGQAIVYVMTGMYGDPSD IGAGVCLLII--------------------------------XNICETIVWKAFSPATVN TGRGTEFEGAIIALFHLLATRSDKVRGLREAFYRQNLPNLMNLMATILVFGIVIYFQGFR VDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAAKFSGNFFINLLG VWADVGGGGPARSYPIGGLCYYLSPPETLGHVAEDPIHAVLYIVFMLGSCAFFSKTWIDV SGSSAKDVAKQLKEQQMVMRGHRETSMIKELNRYIPTAAAFGGLCIGALSVLADFLGAIG SGTGILLAVTIIYQYFEIFVKEQSEMGGMSTLLFXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX MVNIPKQRKTFCKGQKCKKHSLHRVSQYKTGKASLVSQGKRRYDRKQKGYGGQTKPIFRK KAKTTRKIVLKMECTECKYRKQLPIKRTKHFELGGDKKKKGQMIQF-------------- ------------------------------------------------------------ -----EGMHTGQFLYCGKKAKLQIGNVLPIGSMPEGTVICNLEEKCGDRGRIARASGNYA TVVAHNQDTKRTRVKLPSGSKKVLASTCRAMVGLV------------------------- ------------------------------------------------------------ -AKRTKKAGIVGKYGTRYGASLRKLIKKMEVTQHGKYTCSFCGKESMKRKAVGIWNCKAC RKTVAGGAYVYSTTAAATVRSAVRRLRETKEXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XMTKGTSSFGKRHNKSHTLCRRCGTSSYHIQKKTCAQCGYPAARRRHYNWSVKAKRRKTQ GTGRMRHMKVVFRKFRNGFREGTVPKPRRA--EGREMAKDLDQWIEQLNECKQLSENQVK TLCEKAKEILSKESNVQDVKCPVTVCGDVHGQFHDLMELFRIGGRSPDTNYLFMGDYVDR GYYSVETVSLLVALKARFPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDFLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHTNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRC GNQAAIMELDDSLKYSFLQFDPAPRRGEPHVTRRTPDYFLMGAYKYIQELWRKKQSDVMR FLLRIRCWQYRQLSSIHRAPRPTRPDKARRMGYRAKQGFVIYRVRVRRGGRKRPVPKGAT YGKPTNQGVNSLKYQRSLQSTAEERVGRRCGGLRVLNSYWVSEDSSYKFFEVIMVDPFHK AIRRDPDTQWITKPVMKHRELRGLTSASKKSRGLGKGHGYNKTTGGSRRANWKRQNMLQM RRKRGIALGRLAEERKTWRKDHPFGFVARPCKSADGTLNLMNWECAIPGKKGTPWENGLY KLRMLFKDDYPSSPPKCKFEPPLFHPNIYPSGTVCLSLLDEEKDWRPAVTIKQILLGIQS LLNDPNIRDPAQAEAYTIYCQNKEEYERRVRAQALLFKD---GRGNKMMQHINYRMRCTL QDGRIFIGTFKAFDKHMNLILGDCDEFRKIKPKGSKAREEKRVLGLVLLRGEALVSMTVE GPPPADEATSRVPLPGGAGGPGLGRAAGRGVPAGGGLSGPVRGVGGPAQSSMMPG--MGR GGPPEPVAIFKMVLVGDGGVGKTTFVKRHLTGEFEKKYVATLG----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------NDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEI KEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ KFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRLESGSGGDSEVQRTMLELLNQLD GFEPKQNIKVIMATNRIDILDSALLRPGRIDRKIEFPAPNEEARLDILKIHSRKMNLTRG INLRKIAEMMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFELAVAKIMQKDSEKNMSV KKLWKLSFAENFALSGAAAVISKTAAAPIERVKLLVQNQDEMIKQGRLSEPYKGVIDCTT RTFRTEGLLPFWRGNLANCIRYFPTQALNFAFKDQIKKAFAFKKTDGYAVKFSKNVASGG AAGAMSLCFVYSLDYARTRLANDAKSGTKREFNGLIDVYRKTLKSDGIGGLYRGFVISCV GIVVYRGCYFGFYDTIKPIALGEDAGLLASFVLGYVVTISAGLVSYPIDTIRRRMMMTSG QAVKYNGSIDCFLKIVKAEGFMSLMKGAGANILRGVAGAGVLSGFDKFKEIYISFRAMSD CSDLDRQIEQLRRCEIIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLK ELFKVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRIMLIRGNHESRQITQV YGFYDECLRKYGSITVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSINTLDQIRAIDRK QEVPHDGPMCDLLWSDPEDTQGWGVSPRGAGYLFGSDVVQTFNAANNVDLICRAHQLVME GYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQRDFTIFEAAPQELRGKPQAEYFL VRLPPEVNRILYIRNLPYKITAEEMYDIFGKYGAIRQIRVGS--------------IFDA KNACDHLSGFNVCNRYLVVLYYQPNKAFKKMDTEKKKDELDAMKSKYGLSTPQKKXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXMPRGPRKHLKRLNAPKHWMLDKLGGVFAPKPSCGPHKTRECLPLMVFLRN RLKYALTYDECKRIVNQRLIKVDGKVKTDKTYPCGFMDVITIEKTGENFRLIYDVKGRFT VHRIKPEEAAYKLCKVKKVSVGPKGVPYIVTHDGRTIRYPDPLVKVNDSIQLMGTKDDEY DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTA GQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADNNIVIMLVGNKSDL RHLRAVPTDEAKAFAEKNNLSFIETSALDSTNVETAFQNILTEIYKIVSQKQIRDSPDDN NVQTITVAPTDNSGEKKKACCTMSERYSFSLTTFSPSGKLVQIEYALAAVAAGAPSVGIK ATNGVVLATEKKQKSILYDEHSVHKVEMVTKNVGMVYSGMGPDYRVLVRQARKLAQQYYL TYQEEIPTAQIVQRVANVMQEYTQSGGVRPFGVSLLMAGWDKRPYLYQCDPSGAYFAWKA TAMGKNFINGKTFLEK-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGLDTQIQEIKESVELPLTHPEYYEEMGIKPPK GVILHGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPS IVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSKGDVKVIMATNRIETLDPA LIRPGRIDRKIEFPLPDEKTKRRIFNIHTNRMTLAQDVDLEDYIMAKDELSGADIKAVCT EAGLLALRERRMKVRNKDFKEAKDNVLYRKNEGTPEGLYLXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXAEFYVRYYVGHKGKFGHEFLEFEFRPDGKLRYA NNSNYKNDTMIRKEAFVHKSVLEELKRIIEDSEIMQEDDALWPTPDRVGRQELEIVIGDE HISFTTSKIGSLVEVNQSKDPEGLRTFYYLVQDLKCLVFSLIGLHFKIKPIXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMTEYKLVVVGAGGVGKSA LTIQLIQNHFVEEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGF LCVFAVNNPKSFEDINQYREQIKRVKDADEVPMVLVGNKVDLPQRLVDTKQAKQVADSYG IPYVETSAKTRQGVDDAFYTLVREIRRFMGDRYNIHSQLEHLQSKYVGTGHADTNKWEWM TNQHRDSFASYMGHFDMLNHFALVENESKARVRFNFMEKMLQPCGPPPERPED-----CA FSGFKIYPGHGKRVVKTDGRSFVFINSKCEKSHAMKRNPRKISWTVMYRRKNKKGQQEEL SKKRTRRTTKFQRAVAGATLTDIMAKRNQKPEVRKAQREQAIRAAKEKQRAKDAMKSRVG GKRMKLNISYPATGCQKLIEVDDDLKLRAFYEKRMAQECSAESLGDEWKGYIVRISGGND KQGFAMKQGVLVPGRVRLLLSKGHSCFRPRRTGDRRRRSVRGCIVDANLSVLNLVIVKKG EQEIAGLTDSTVPRRLGPKRASKIRKLFNLSKEDDVRQYVVRRPLPGKSKAPKIQRLVTP VVLQRKRHKLALKKRRSTKKREDAADYAKLLAQRMKEAKERKMERRRSASHSKKVKAKDL RGKKREDLVKQLEELKQELSQLRVAKVTGGAASKLSKIRIVRKSIARVFTVMNQTQKENL RKFYKPKDLRLKKTRAIRRQLTKHEAALKTKKQQRKDRLYPVRKYAVK-------VTNKV FFDVKQGDEDLGRIVIGLFGETAPLTVKNFIALATKS-GYETSTFHRVIDGFMIQGGDFS ARDGSGSKSIYFDDENFKLDHYGAGWVSMANAGKDTNGSQFFITTVETKWLNGKHTVFGK VLEGMEIVRKIEKTKVGKDDPIVDIVIAKSGSLEVTTPFDV-------XXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNKDEKGEDDKVYGGCEGPDAMYVKLV SSDGHEFIVKRDHALTSGTIKAMLSGPGQFAENETNEINFREIPSHVLQKVCMYFTYKVR YTNSSTEIPEFPIAPEIALELLMAANFLDC------ADLENHCKDGGLWVVIHGRVYDIQ DFKSNAPCGAEVLLDYAAKDATEVFEQVFHTDKARAMMNNYYIGNYLDPDHALL------ --------------MSYMLQHLNNGWQVDQAILCEEERLTVIRFGHVW-----XMDETLM NAAEKLKNFCIIYLVDITEVPD--------XXCTVMFFYRNKHIMIDLGTGNNNKINWAM EDTQEFIDIVETVFR---------------------KKLQRQLEFLEVQEEYIKDEQKNL KKEYLHAQEEVKRIQSVPLVIGQFLEAVDQNTGIVGSTTGSNYYVRILSTIDRELLKPSA SVALHKHSNALVDVLPPEADSSITMLGADEKPDVQYADIGGMDIQKQEVREAVELPLTHF DLYKQIGIDPPRGVLMFGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVR DVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTVNVKVI MATNRHDTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITGKMNLSEEVDLEDYVARPD KISGADINAICQEAGMQAVRENRYVVLSKDFEKGYKNNIKKDETEHEFYK---PLTISMV RERVILVLKLYDKINPEKLTVDSHFINDLGLDSLDHVEVVMQMEDEFGFEIPDEDAERLM KPADIVQYVCDKEDVSRRV--LTDDMKNVEFETSEDVDITPTFDSMGMREDLLRGIYAYG FEKPSAIQQRAIKPICKGRDVIAQAQSGTGKTATFSISILQALDTQVRETQALVLSPTRE LAGQIQKVVLALGDYMSVQCHCCIGGTNVGEDIRKLDYGQHVVSGTPGRVFDMIKRRNLR TRSIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTSKFMTDPI RILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKM REANFTVSSMHGDMPQKEREAIMKEFRSGASRVLITTDVWARGLDVQQVSLVINYDLPNN RELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI-ALRRP FDPVAHELDPNFRLTKFADLKGGCKVPQEVLLKLLEGL-QAQEVEQSHFSYVAAVPRIGI GMDACVTPLRHGGLSLVQTTDFFYPLVDDPYMMGKIACSNVLSDLYAMGVTECDNMLCLL GVSTKMSDKERDVVVPLLLRGFKDQADEAGTSVNGGQTVLNPWMTIGGVATTVCQPNEFI MPDNAVVGDVLVLTKPLGTQVAVNAYQW---------------------AYQRAMFSMAR LNRTASRLMHKYNAHGATDVTGFGLLGHANNLARIQKNEVGFVIHNLPVIAKMAAVSKAC GNMFGLLQGQSAETSGGLLIALPREQAAAYCKDIEKTEGYQAWIIGIVEKGTRSARIIDK PRVIEVPAKEKD----IFSGIECYFINIDAHAEECFFDKVSSGTKMSLMFEVAEGGFLDI DVKISGPDGKSIYSGDRESNGKYTFAAHMDGVYKYCFSNKMSTMTPKIVMFSMDLGDKPK EHHNKLEDMVNELSTSLTGVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMT LGQIYYLKRFFEVRRVVQSATLKPYLNAVRHTLTAALCLENFSSQVVERHNKPEVEVRSS KELLLTPVVISRNEKEKVLIEGSINSLRISIGVKQADEIEKILCHKFMRFMMMRAENFII LRRKPVKGYDISFLITNFHSEAMFKHKLVDFIIHFMEEIDKEISEMKLAVNSRARISAEE FLKRFSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLV TMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTMANTFKTLDSWRDEFLIQASPRDPEN FPFVVIGNKIDLENRAVSQKRAQGWCHSKGDIPYFETSAKEAINVEQAFQTVAKNALAQE TEVELYNEFPDQIKLT----------TAPFDSRFPNQNQTRNCWQNYVDFHRCQKIEDYE PCTYFFKVYKTLCPVGWTSKWDEQMEAGIFPAKI-------------------------- --------------------------------VNELSGIKESDTGLAPPALWDLAADKQT LQSEQPLQVARCTKIINADSDDPKYMINVKQFAKFVVDLGDQVAPTDIEEGMRVGVDRNK YQIHIPLPPKIDPTVTMMQVEEKPDVTYSDV----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------IHGRTMSMEKNIRFELLARLCPNSTGADIR SVCTEAGMFSIRARRKSISEKDLIEAVNKVIKGYQKFSATTKY----MGAEKKHINIVVI GHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITI DIALWKFETPKYFVTVIDAPGHRDFIKNMITGTSQADCAVLICASSVGEFEAGISKNGQT REHALLAYTLGVKQLIIGVNKIDNTEPPYSKARFEEIQKEVSSYVKKIGYNPDTVPFVPI SGWHGDNMLNTSWFSGWKVYSGKTLVQALDNIDPPKRPTDKPLRLPLQDVYKIGGIGTVP VGRVETGVLKPGMVVSFAPNVVTTECKSVEMHHESLTEATPGDNVGFNIKNVSVKEIRRG NVCGDSKNNPPKEAKTFIAQVIILNHPGQISNGYAPVLDCHTAHIACKFSEIQKKIDRRS GKELEDAPKFVKSGDAAIVNMTPQKPMCVESFSEFPPLGRFAVRDMKQTVAVGVIKSVEK VE-KAGKVTKAAAKA--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------DASAKLWDIRDGMCRQTFSGHES DINAITFFPSGAAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLG GYDDFNCNVWDTLRQDRAGVLAGHDNRVSCLGVSEDGNAVATGSWDSFLKIWN------- ------------------------------------------------------------ -------YYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARR DVKKEEGEAFAREHGLIFMETSAKTAANVEEAFINTAKEIYQKIQDGVFDINNESNGIKL GPQQSRSQGPGGGGDSQSGGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPRQ IMEIKDFLLKARRKDAKSVKIKKNVKFKVRCSRFLYTLVIQDREKAEKLKQSLPPGLQVK ELKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMADADKLNIDSIIARLLEVRGSRPG KNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLTAGRPVTPPRGAAKGK GK-MFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIK---XXXXQSLVLEIVGTNVSTT YITCPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKN------------------- ------------------------------------------------------------ -------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSAIFNFQS LLTVVLLLICTCAYIRSIAPRMLDKNKEGLLGLFWKCARIGERKSPYVAVCCIAMAVSIL FFS--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ GIKAVDSLVPIGRGQRELIIGDRQTGKTAIAVDTIINQKRFNEGQDEKSKL--------- ---------------------XVVSATASDAAPLQYLAPYSGCAMGEYFRDNGKHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDDFGGGSLTALPVIE T----------------------------------XXXVGLSVSRVGSAAQIKAMKQVAG SMKLELAQYREVAAFAQFGSDLDASTQQLLNRGVRLTELLKQGQYVPMAVEEQVAIIYAG VRGMLDKVDPSKITKFEQAYLKHLQSSQQEVLSTIAKEGKITDATEAKLKEIVLNFLAGF MEAVYSIPFNFLQCPNLKLKKPSWVKQPSAMFMFGCILLSYFLVTGGIIYDVIVEPPSIG STTDERGNSKPVAFMPYRVNGQYIMEGLASSFLFTLGGLGFIILDQTNNPSTPKLNRILL LSVGFVCILISFFMCRVFMRMKLPMPKVKRSKKPPPEGWELIEPTIDELDQKLREAETDP HEGKRKVEAMWPIFRIHHQKSRYIYDLFYRRKAISRELYEYCLKERIADKNLIAKWKKQG YENLCCLRCIQTRDTNFATNCICRVPKAKLEEGKIVECVHCGCRGCSGEYAQVTKMLGNG RLEALCFDGIRRLAHIRGKLRKKVWINAGDIILLGLRDYQDAKADVILKYTVEEARNLKT YGELPETTKINEDEDDNITFEGIDDILVRFLMKLSHETVTIELKNGTQVHGTITGVDVSM NTHLKAVKMTVKNKEPVQLETLSIRGNNVRYFILPDSLPLDTLLIDDAPKFRKPGXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXE GNADKGKKIFVRSCSQCHTVEQGGKHKVGPNLHGLFGRKTGQQPGFSYTDANKNKGITWG EDTLWEYLANPKKYIPGTKMVFAGLKKEKERADLIAYLKSST-IFVERTLAIIKPDAVSE EIEDIILRSGFTVIQKRRVHLTPEQASDFYAEHYGKMFFPSLVAYMSSGPILAMCLAREK AIAYWRELIGPTNTLKAKETHPDCLRAIYGTDDQRNALHGSDGYSAAER----------- -------------------------------------------------------MFEAR LAQGAVLKKVLESVKDLLTEGIWDCQGTGMSLQAMDASHVALVALKLQSDGFDTYRCDRN QSMGISLTNMSKILKCAGNDDGITIKAVDNSDTVSFMFESPNQEKVSDYELKLLNIDQEH LGIPETDYCAVIKMPSGEFQRICRDLSQIGESVVIACTKEGVKFSSTGDMGTGNIKLVQS ANVDKEEESVQIEMQEPVTLTFALRYLNFFTKAT-------------------------- ----------------KTLAAYHTSQSVAKGQIVAVIGAVVDVQFEDELPPILNALEVQD RSPRLVLEVAQHLGENTVRTIAMDGTEGLVRGNVCTDVGSSIRIPVGPATLGRIINVIGE PIDERGPVNTDKFASIHQEAPEFVDMSVEQEILETGIKVVDLLAPYAKGGKIGLFGGAGV GKTVLIMELINNVAKKHGGYSVFAGVGERTREGNDLYHEMIQTGVISLKDDTSKVSLVYG QMNEPPGARARVCLTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTKKGSITSVQ-----------------------------XXX ELGIYPAMDPLDSTSRILDPNVVGAEHYDTARGVQKVLQDHKSLQDIIAILGMDELSEDD KLTVARARKMQKFLSQPFQMAEVFTGSEGKLVPLSETIKGFKMILSGELDHLPEIAFYMV GNIEEVVAKAERLAEEQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXMGKQNSKLKPEVLDDLRSNTEFTDQEIHEWYKGFLKDCPSGHL SVEEFKKIYGNFFPYGDASKFAEHVFRTFDTNHDGTIDFREFICALSVTSRGKLEQKLKW AFSMYDL--------------------------KLPDEESTPEKRVDKIFRMMDKNHDDI LSLEEFKDGSKKDSTITQAL----MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNL TGLNEQVPHYRQALDMILDLEPDDELEDNPNQSDLIEQAAEMLYGLIHARYIMTNRGIGQ MIEKWQQGDFGYCPRVYCENQPMLPIGLSDVPGEAMVKLYCPKCQDVYTPKSSRHHHTDG AYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPLAYQIQTQAS------------ XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------------- ------------------------------------------------------------ --------PAQAITIEAEPRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEY STETREELLYNKEKLLNNGDKWEAEIAANLQADHLYRXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXAAQGKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQT VCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVKELQRQ ASPNIVIALAGNKADLRMVEYDEAQAYAEENSLLFMETSAKTAMNVNDIFLAIAKKLPKS EQGVDLNEQNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFLTRSEYDRGVNTF SPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVVLAVEKRVTSSLIEPSSIEKIVEIDTHIG CAMSGLIADSRTMIDKARVEAQNHWFTYNERMTVESVTQSVSNLALAFGDDDAGP-AMSR PFGVALLFAGIDDKGPQLFHMDPSGTFIQFDAKAIGSGSEGAQQALQEVYHKAMSLKEAK KNALTILKQVMEEKLNATNVEMGVCVPGTMFTMCTKEEIEDVIKDIAQKTWEMSNSVENV GTVDEIYRYDKKQQQDILTAKPWEKDPHYFKNIKISALALLKMVMHARSGGNLEVMGLLL GKVDGNQMIVMDSFALPVEGTETRVNAQAQAYEYMAAYTESAKQVGRLENAIGWYHSHPG YGCWLSGIDVSTQMLNQQFQEPFVAIVVDPIRTISAGKVNLGAFRTYPKGYKAPDESQSE YQSIPLNKIEDFGVHCKQYYPLDVSYFKSGLDRRLLESLWNKYWVNTLSSSSLITNADYT TGQIFDLADKLEQSEGQLGRGGFMDKKSEDKLDKATKDGCKTTMEAIHGLMSQI------ --------------------------------------------KDSPYEHGVFKLELFL PEEYPMSAPKVRFMTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPD DPLANDVAEKWKTNEEQAIETAKAHTRLYA------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------PMEVYVDDDSKLTLHGLQQHYVKLKDNEKNRKLFELLDVLEF NQVIIFVKSVQRCVALSQLLVEQNFPAIAIHRAMPQEERLSRYQQFKDFSKRILVATNLF GRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAVTFV--------PPSYSDLG KSARDLFGKGFNFGFHKLDVKTKSSNGVEFKTCGSSNQDTGKINANLETKYKWGEYGLTF TENWNTDNVLATEIAIEDQLAKGLKLTFDTSFAPQTGKKSGKIKTAYKQEYVNANVDVDF DFAGPTVHGAGVLGYNGWLAGYQMSFDKSKLSRNNFSVGYSSGDFQLTTNVNDGAEFGGS VYQKLNSNLETGVQLSWAAGSNATKFSLAAKYTPEPDSTFRAKVNNSSQIGLAYSQKVRD GVTLNLSALVDAKNFNAGGHKLGFGLDLQA-SDREKVLGDYRKKLVEHKELEARLKEMRD QLKELTKQYDKSENDLKALQSVGQIVGEVLKQLTEDKFIVKATNGPRYVVGCRRQLDKTK LKAGTRVALDMTTLTIMRYLPREVDPLVYNMQAEDPGNISYSSVGGLGEQIRELREVIEL PLLNPELFQRVGITPPKGCLLYGPPGTGKTLLAKAVASQLDANFLKVVSSAIVDKYIGES ARLIREMFGFARDHEPCIIFMDEIDAIRRFSEGTSADREIQRTLMELLNQMDGFDTLGKV KMIMATNRPDTLDPALLRPGRIDRKIEIPLPNEQARMDILKIHAQPIAKHGEIDWEAVVK LSDDFNGADLRNVCTEAGMFAIRAERDFVIEEDFMKAVRKVAENKKLESKLDYKPVXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXVIDHYENPRNVGAMDKKEKAVGTGLVGAPACGDVMKLQIKVDDNG KIVDAKFKTFGCGSAIASSSLATEWIKGKSLDEAGAIKNTDIAKELCLPPVKLHCSMLAE DAIRAALSDYKLKNSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXMGKFMKSGKVVLVLGGRYAGRKAVIVKNYDEGTTDKPYGHALVA GIERYPRIVTRRMGKKRIAQRSKVKAFVKVYNFNHLMPTRYSVVPMDKNLINKDAFRDPA LKRKARREAKAKFEERYKTGKNRWFFQKLRF---FIMIKPDAVQRGLVGKIISRFEEKGF KLVAMKQKTASKELLEE---------------------------------------LGET NPKDSKPGTIRGDYCIQVGRNICHGSDAVESAKREIALWFDKSELNDWTPCSSTWVYEAE APKPVKTPTKVKEKALKARKNVLKGNRETRKRKQMMTVHFRRPKTLRLARAPRYPRKSTP HRNRLDQFKIVKFPLTTESAMKKIEDNNTLVFIVDIRANKPQIKTAVKKLYDIDVAKVNT LVRPDGEKKAYVRLAPDYDALDVANKIGII----------------------SVPKSLKP EEDKYPVGPWLIGLFIFVVCGSAVFQIIQTIMMVRIKGWTAVATWRWVANDDNCGICRFA FDGCCPDCRLPGDDCPLVWGQCSHCFHIHCIVKWLNSQQVHQLCPMCRQEWKFKEXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XMGGLLSYFSGLFGSKERRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVIYKN LKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSMDRDRIGISKQELVSMLEEDELKKAI LVVFANKQDIEGAMTVTEVANALGLSSLKNRKYQIFKTSAIKGEGLDEAMDWLSNSILQQ K----------------------------------------------------------- ---------------------------------WFGGGQLRVHLDIQVGEHANDYKEIAQ KDKLTELQLRVRQLLDQVEQITKEQNYQRYREERFRQTSESTNQRVLWWSIGQTSILLVT GFWQMRHLKSFFEAKKLV------------------------------------------ -----------------------------------------------------GLFTEIG PLSCFISRHSIPGDMEFDPNSNPPCYKTKDEDIVIQQDDEIRIKIVGTRVDAADIFAIGS LMDDYLGLVSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMAKKTY DLLFKLLLIGDSGVGKTCLLFRFSDDAFNTTFISTIGIDFKIKTVELGGKKIKLQIWDTA GQERFHTITTSYYRGAMGIMLVYDITNAKTFDNISKWLRNIDEHANEDVEKMILGNKCDM EDKRQVSKERGDTIAREHAIPFLETSAKSNINVEKGFMDLAQAILNK------------- ------------------------------------------------------------ -----------------------SEAKVLSNMIKQKRKEKAGKWDVPLPKVKGVSEAEVF RVVKTGKTKRKAWKRMVTKATYVGEAFTRKPPKYERFIRPMALRMKKAHVTHPELKATFC LPIIGVKKNPSSPMYTSLGVITKGTVIEVNISELGLVTQGGKVIWGKYAQVTNHPENDGC INAVLLVMAARPLITVYSEKNEATGTNITLPAVFRAQIRPDIVSFVHNQIRKNSRQPYAV NKLAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRNWHRR INVNQKRYAICSAIAASGVPALVMSKGHRIEQIPEVPLVMSDKIEELKKTKEAVQVLKKL KAWPDIQKVVSSKRFRAGKGKMRNRRRIQRRGPLVIYEKDNGICRAFRNIPGITLINVSR LNLLKIAPGGHVGRFCIWTESAFKKLDALYGTWRVPSKEKNG------------------ ------XIRAPKRSNTRKIIKKNPLKNIRSMLRLNPYAAVEKRNAIRKKARQEATDKRRG IA---------------GSMEQEMATRTLQIQSKRFYLDVKQNRRGRFIKIAEVGSGGKK SRLLLAMSTAAEFRDHLTDFSEHYASLGPPNPENVPEDGKLKSEVMVKDNRRYYLDLKEN QRGRFLRVSPRSQQRSQIAIPAQGMIEFRDELTALLDEFGTDDHETQGDLPESRSMRVEN KMFYFDVGSNRRGVFLRVSETNFRTAITIPERSWTRFRDMMNEFVERDDRRVRDAQMRAT INQKLVETGERERLKELLRTRLIECGWRDQLKAHCKEVVRQKGLEHVTVDDLVSEITPKG RA-----------------------MNVRNARPEDLMNMQHCNLLCLPENYQMKYYFYHG LSWPQLSYVAEDENGKIVGYVLAKMEEDPEDSVQHGHITSLAVKRSHRRLGLAQKLMDQA SRAMVESFQAKYVSLHVRKSNRAALHLYTQSLKFQISEIEPKYYADGEDAYAMRRDLSKE FPKSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMAEEGGDKKETQTSR VVHTYPLIRHSDMGDEMKTETMELCVTACEKFANNNESAAKMVKETMDKKFGASWHVVVG EGMGFEITHEVKNLLYMFFQGTMAIVVWKCS----------------------------- ------------------------------------------------------------ ---------------------------------YSSKKKAFTKYSKKWQDESGKKEIEKD FAQLKKYCKVIRVIAHTQMKLLKKRQKKAHIMEIQVNGGTVSEKVDWAREKMEKQVPIAE VFGQDEMIDCIGITKGKGYNGVTSRWHTKKLPRKTHKGLRKVACIGAWHPSRVAFSVARA GQKGYHHRTEVNKKIYRIGQGIHTKDGKVVKNNASTE----------------------- -------CMGPKKRVITLRKSLITHTSRKSLENIKLKFIDTSSKFGHGRFQTPEEKHHVM GPLKKDMQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLG LWDTAGQEDYDRLRPLSYPQTDVFLICFSLISPASFENVRAKWYPEVSHHCPNTPIILVG TKLDLREDKETIEKLKEKKLSPITYPQGLAMAKEINSVKYLECSALTQKGLKTVFDEAIR AVLCPKPKAKKK------------------------------------------------ ------------------------SDRDYTYDELLTRVFDKMREKNPDMVAGEKKRFVMK PPQVMRVGTKKSSFSNFAEICKALHRQPKHLLAFLLAELGTSGSIDGMNQLIIKGRFQQK QIENVLRRYIKEYVTCHTCRSPDTILQKDTRLFFLQCETCGSRCSVASIQSGFKAVTGKR AAIRAKTS---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------FILATGSADKTVA LWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQSAEDA DDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEEPDTPAS ELE-PAPSRARVYADVNTNRPREYWDYESHTVEWGQQDDYQIVRKLGRGKYSEVFEAINI TNNEKCVIKILKPVKKKKIKREIKILENLRGGTNIITLLAIVKDPVSRTPALVFEHVNNT DFKQLYQTLTDYDIRFYLFELLKALEYCHSQGITHRDVKPHNVMIDHENRKLRLIDWGLA EFYHPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPFFHGHDNY DQLVRIAKVLGTDELYEYIDKYQIQLDPRFNDILGRHSRKRWERFVHSENQHLVSPEALD FLDKLLRYDHQERLTAREAMDHPYF------XXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSKAHPPELKKYM DKKMTLKLNAKRSLTGILRGFDPFMNLVIDEAVEHTKTGEQNSIGMVVVRGNSIVLLEAL ERIEFGNPLRKFKLVFLGEQSVGKTSIITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTI RLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFQQTSKWIDDVRTERGTDVIIM LVGNKTDLSDKRQVSTEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMEQTDQ KKMIEVKLKDTPTEPET--VKYQVCVGRDRGYKQTARPQKPSNRRGRLTKQAKFTRDVVR EIVGFAPFEKRILELLKNDREKRALKFAKKRVG----------------------XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSTMNPEYDYLFKLLLIGDSGV GKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYR GAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEY ADQLGIPFLETSAKNATNVEQAFMTMAAEIKNRMGPVTTASNVKINASTPVKQGGGGCC- -SMGEEVLRMGNDEIIGRTRLLDNEIKIMKSEVMRISHELQAQKEKIKENTEKIKVNKTL PYLVSNVIELLDVDPEDAAEEEGANVDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDPENL HPGDLVGVNKDSYLILENLPAEFDSRVKAMEVDERPTEQYSDIGGLDKQIQELIEAVVLP MTHKERFEALGIQPPKGVLLYGPPGTGKTLMARACAAQTKSTFLKLAGPQLVQMFIGDGA KLVRDAFALAKEKTPAIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFSSHEG IKVIAATNRVDILDPALLRSGRLDRKIEFPAPNEEARARIMQIHSRKMNVSSDVNFEELA RCTDDFNGAQCKAVCVEAGMIALRREAVELIHEDYMDAILEVQAKKKTNLNYYAKDAADQ NFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRQDKRVKLQIWD TAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDNAQVVLVGNKC DLEDERVVSTERGKQLADQLGLEFFETSAKENINVKAVFERLVDIICDKMSESLDSDPTK TTRLTENPNQQNQQCQCALTHKLAIERDYISQPRLTYKTVSGVNGPLVILDDVKFPKYAE IVQLTLQDGSKRSGQVLEVSGSKAVVQVFEGTSGIDARHTTCEFTGDILRMPVSEDMLGR VFNGSGKPIDKGPNVLAEDFLDIQGQPINPWSRTYPEEMIQTGISAIDGMNSIARGQKIP IFSANGLPHNEIAAQICRQGSLVKLPGKSVHDDHSDNFAIVFAAMGVNMETARFFKQDFE ENGSMENVCLFLNLANDPTIERIITPRIALTTAEFLAYQCEKHMLVILTDMSSYAEALRE VSAAREEVPGRRGFPGYMYTDLATIYERAGRVDGRSGSITQIPILTMPNDDITHPIPDLT GYITEGQIYVDRQLQNRQIYPPINVLPSLSRLMKSAIGEGMTREDHADVSNQLYACYAIG KDVQAMKAVVGEEALTPEDLLYLEFLQKFEKNFIAQGHYENRTIFETLDIGWQLLRIFPK EMLKRIPAEKLAKYYPRQ--GPGFVGIKFCQECNNMLYPKEDKEN-----------XXQE AENPCIYVNKITHDVDELTQIIADVIADPTLPRTEDHPCPKCHHKEAVFFQSQSTSAEQG MRLYYVCTNSNCAHRWTEKVPYKVADISLAEWGRKEIALSENEMPGLMHMRRTYGPSKPL KGARIAGCLHMTVQTAVLIETLTELGAQVTWSSCNIFSTQDHAAAAIAKTGVPVYAWKGE TDEEYVWCIDQTIIFPDGEPLNLILDDGGDLTNLVHEKYPQYLPGIKGLSEETTTGVHNL YKMMTAGKLKVPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDIMLAGKVAVVAGYGDV GKGCATALRAFGARVIITEIDPIIALQAAMEGYEVTTFDEAVKEGRIFVTTTGCKSIIEP KHFEQMHENAIVCNIGHFDCEIDVKWLNDNC-KKDNIKPQVDRFTLSNGRSIILLAEGRL VNLGCAMGHPSFVMSNS-----------------------XLPKKLDEEVAAAHLDHLGV KLTKLSDTQSEYLGIPKEGPFKPEHYRY-DEVDQVAAPAVEEPLDLVRLSLDERIYVKMR NDRELRGRLHAYDQHLNMILGDVEETVTTLEIDEETFEEIYKSSKRNIPMLFVRGDGVIL VSPPMRTMSTSNVENLSPQMIRQVAKELTELQSDPPEGIKVYPNEEDITDIQATIEGPAG TPYAGGMFKMKLVLSKNFPHEAPKGFFLTQIFHPNVAKNGEICVNTLKKDWKASLGIKHV LLTIKCLLIVPNPESALNEEAGKLLLEQYDDYSTRARIFTDIHAKP-------------- ----GLKVNENRTIAAA-GSDEVEFGSTKYFALCGFGGILSCGITHTAIVPLDLVKCRIQ VDPDKYKGIVTGFRVSLSEGGVRELGRGWAPTLIGYSMQGLCKFGLYEVFKCLYSDLLGE EKTFQWRTSLYLAASASAEFFADIALCPMEAIKV-------------------------- ------------------------ERTVEALYSYVVPKPRSECNKQEQLVVTFVAGYIAG VFCAVVSHPADTIVSKLNQEKGSTFMEVGKKL---------------------------- -------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNEQQEEDASELQFPKEF ENAETLLISEVQRKQQNECAEDEQ--------------------------XVRSLLMQKK LHKFELAALANLCPENADEAKSLIPSLEGRFEDEELQQIQDDIQTKRSFQY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------LQNKIDIVKESQ ARDQYEQILKFVQGTVAEGAPIVPISAQLKYNIEVICEYVTKKIPVPLRDFTSAPRLIVI RSFDVNKPGCEVEDLKGGVAGGSILKGVLKVGQEIEVRPGIVAKDADGKLTCKPIY---- ---------------------------------------------PEIYTELEISYFLLR RLLGVRVEGDKKGAKVAKLSKNDILMVNIGSLSSGGRVLAVKADLAKIGLTNPVCTEIGE KIALSRRVEKHW----------------MAELLLDPDIRLWVFLPIVLITFLVGIIRHYV TILLQSEKKVESTQIEDSQLLIRSRLLRENGKYLPRSAFRMRKAFLEGK----------- ---LKADMLKGNLTNVLPMIVIGGWINWAFSGFLTTKVPFPLTFRFKPMLQRGVELITLD ASWVSSASWYFLNVFGLRSMYNLILGMDNAADQTRMMQDQMTGSAMQV-QDPSKALTAEW EALKITNYNNALEGVEEDIL---------MLNYLGLYKKSGKLVFLGLDNAGKTTLLHML KDDRMAQPVPTLHPTSEELSMGGMKFTTFDLGGHQQARRVWKDYFPAVDGIVFLVDALDR ERFTEAKAELDSLLTDEQVASAPVLILGNKIDAAGAASEDELRHHFGLHGQTTGKGTVAK NDLRPMELFMCSVLKRQGYGEGFRWLAQYINIIRRNRSGTKTTDWCNWPDESFDEMDSTL AVQQFIQQSIRKDFSNIDEILTPPDGQDEGVWKYEHLRQFCMELNDLAVKLQNDCNPETC TQMTATEQWIFLCAAHKTPKECPAIDYTRHTLDGAACLLNSNKYFPSRVSIKESSVAKLG SVCRRVYRIFSHAYFHHRQLFDEYENETSLCRRFTVFVTKYNLMSRDNLIVPILEDQMPN IKLQSSDGEIFEVDVEIAKQSVTIKTMLEDDEDEDEAVPLPNVNAAILKKVIQWCTYHKD DPPPPEDDENKEKRTDDISSWDAEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMI KGKTPEEIRKTFNIKNDFTPAEEEQVRKENEWCEEKXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSASAVFI CDVKGKVLISRNYRGDIDMSVVDKFMTLVMEMEDEATLTPIIQHGNVTFCYIKYNNLYLL TTTKKNANVALSFSFLHKIVQVFCEYFKELEEESIRDNFVIIYELLDELMDFGYPQTTDS KILQEYITQESHQVEVQARPPSTVTNAVSWRSEGIKYRKNEVFLDVIESVNLLVSANGNV LRSEIVGAVKMRVYLSGMPELRLGLNDKVLFESTG------------------------- ----------------------HVKPLIWVESVIERHAHSRVEYMIKAKSQFKRRSTANN VEIIVPVPQDADSPKFKTTVGSCKYSPELNAVVWSIKSFPGGKEFLMRAHFGLPSVMSED TEGKPPIHVRFEIPYF--------------------------------------MSVLQR IAEIEAEMARTQRNKATSGHLGLLKARLAKLRRELIEPKGGGGGAGEGFDVAKTGDARIG FVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKVQLLDLPGIIEGAKDG KGRGKQVIAVARTCSLIFIVLDVLKPLQHKKLIEHEVEGFGIRLNKEPPKIGYRRKEKGG INLTSTVTQSELDLDLVKTILNEYKIHNADITLRSDATSEDLIDVIEGNRVYIPCIYILN KIDQISVEELDIIYKVPHCVPISAHHKWNFDDLLEKMWDYLKLVRIYTKPKGQLPDYESP VVLKASAVSVEDFCNKLHRSIMKEFKVAIVWGSSVKHQPQRVGKDHLLQDEDVVQIVKRM AKHHPDLIFCRKQAGVAIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGSYQGRCVIC GGPGVSDAYYCKECTITEKDRDGCPKIVNLGSAKTDLFYERKKYGFKKR----------- ------------------------------------------------------------ ---AADFVQAFCLGFEVDDALALVRLDDLYLESFQVTDVKPLKGDHLARAIGRIAGKSGK TRFTIENVTKTRIILADQKVHILGSFQNIKIARTAICNLILGSPPSKVYGTMRAIASRSA ER---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ILKRYDGRFKDIFEEIFQADYVKQFDD AKIWYEHRLIDDMVAQCLKSSGGFVWACKNYDGDVQSDIVAQGYGSLGLMTSVLVVPDGK TVEAEAAHGTVTRHYREHQKGNPTSTNPIASIFAWTKGLEHRAKLDDNPDLAKFCQTLEN ACVQTVENGLMTKDLAGCIHGLKNVTPEHYLYTMDFLQAIAEQLE--------------- ----------KTTVLYKLKLGQSVTTIPTVGFNVETVSYKKIKFNVWDVGGQDKIRPLWR HYYTGTQGLIFVVDCADRDRIDEAKQELHRIINDREMRDAMVLIFANKQDLPDAMKPHEI QEKLGLTRIRDRVWYVQPSCATTGDGLYEGLTWLSSNSKSFGDLKSAAGLKALDDFLGDR SYIVGYTPTQADVVVFEALSGPSSDLYNALRWYNHIASYASQKSGFPGEKKALSEYGPSA ADDEDSDDDIDLFGSDMQKKKQALVDAYNAKKGPALIAKSMIILDVKPWDDETDMALVEK KVRAIEKDGLVWGTSKLIAVGYGIKKLQISCVVEDAKVGTDFLEESICGFEDLVQSMDVA AFNKL----------------------------------SQGMVGQVTARRAAGIILEMI KDGKIAGRACLIAGQPGTGKTAIAMGMAQALGQDTPFTAMAGSEIFSLEMSKTEALTQAF RKSIGVRIKEETEIIEGEVVEIQIDRPAAGTGAKVGKLTLKTTEMETIYDLGQKMIESLT KEKVQAGDIITIDKATGKITRLGRSFTRARDYDAMGPQTKFVQCPEGELQKRKEVVHTVS LHEIDVINSRTQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIVPGVLFIDEVHM LDIECFSYLNRALETDMAPVLIMATNRGITRIRGTNYQSPHGIPIDLLDRLLIIATTPYE EKEVKQILKIRCEEEDVEMSDDALTVLTRIGMETSLRYSIQIITSANLVCRKRKGAEVNV DDIKRVYALFLDESRSTQFLKEYQQEFMFNE----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------MQDWDTAMEDLNRLKEVIDSALTSLQQRTWLI HWSLFVYFNHPKGRDSIIDMFLYEPQYLNAIQTMCPHILRYLTTAVITNKTVLKDLVKVI QQESYKYRDPITEFLECLYVNFDFDGAQQKLRECEKVLVNDFFLVACLDDFIENARLFIF ETFCRIHQCISINMLAEKLNMPSEEAERWIVNLIRNARLDAKIDSKLGHVVMGTQSVSPY QQVIEKTKGLAFRSQMLSMNIDKKLGAKQMGVEREIITPGNGDTKPKQGQTVEVHYTGTL PDGTKFDSSRDRKKVFTFEVGKGQVIKGWDEGVAQMSVGERAKLTCSPDYAYGPRGYPGV IPPNATLIFDVELLAIKMPKYYCDYCDTYLTHDSPSVRKTHCSGRKHKENVKLYYQKWLE DQVQKLVDDTTAAFKQGKITQNPFGSGGAMIPPPASLGPGPGGPGGPPGGPGPMGPGGPM GPPMMPMRPM-GMMGP-QPLTLTRDISRAIELLDQLQKSGEVTKLASLQKVLQSEFLGAV KEVYEHVYETVDVGGSAEIRANATAKATVAAFAASEGHAHPRVVEMPKTDEGLGFNVMGG KEQNSPIYISRIIPGGVADRAQTLKRGDQLLSVNGVSVEGEPHERAVDLLKAAQGSVKLV VRYTPRVLEEMEARFDKQRASAR------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------IADPDAKKPDDWDDDMDGEWEPPMIDNPEYQGEWKPKQIDNPAY KGKWIHPEIDNPDYVADDKLYLYEDFGAIGFDLWQVKSGTIFDNILITDDEDYAKEQGQE SWGKTKDAEKEMKDKQDEEERKQREEEEAKRKEEEGEDDE----------EPSLYTVKAI AIMDNDGNRMIAKYYDDTFPTTKEQKNLFNKTHRANAEIIMLEGLTCVYRSNVDLFFYVI GSANENELILVSVLNAFYDAISQILRKNVEKRALLENLDATFLAMDEICDGGIILEADPM SVVQRVAIRMDDVPLGEQTVA----------------MNIFRLVGDLSHLLAILLLLWKI WKTRSCAGVSGKSQIMFGLVYITRYLDLFTNFISIYNTTMKAIFIAVAIATIYLIYFKFK ATYDSNHDTFRMEFLIVPVGGLAFLVNHDFTALEILWTFSIYLESVAILPQLFMISKTGE AETITSHYLFALGSYRALYIVNWVYRYYFEGFFDLIAIVAGCVQTILYCDFFYLYVT--- ---------MKIEEVKSTTKTQRIASHSHIKGIGLDENGYAIQSAAGLVGQELAREAAGI VVELIRSKKMAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEV LMENFRRAIGLRIKETKEVYEGEVTELTPCETENPMGGYGKTVSHVVIGLKTAKGTKQLK LDPSIYESLQKEKVEVGDVIYIESNSGAVKRQGRSDTFATEFDLEAEEYVPLPKGDVHKK KEVIQDVTLHDLDIANARPQGGQDIMSMMGQLMKPKKTEITDKLRKEINKVVNKYIDQGI AELVPGVLFIDEVHMLDIECFTYLHRALESTIAPIVIFATNRGKCLIRGTEDIISAHGMP LDLLDRIMIIRTLPYSQEEMTQILKIRAETENIEICEESLQQLGAIGTKTTLRYAVQLLT PSNLLAKINGKEGISKEEIEEMSELFYDAKQSAKILAEQGDKFLKDFDEDAEGDQGLLKL KEKVKKRKGRGFETKNDVQEYEGMEVGGPGPQRSVEGWILFITNVHEEAQEDDIYDKFAE HGEIKNTHLNLDRRTGFLKGYALVEYETFREAQAAIESLNGTDILGQQVNVDWCFVRGPA GKKMSYQLYRNTTLGHTLQESLDELIQCGQLSPELALKVLLQFDKAINNALANRVKNRVN FKGHLNTYRFCDNVWTFVLNDVEFRKVDKVKIVACDGKS--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GDAGLTGRKIIVDTYGGWGAH GGGAFSGKDFSKVDRSAAYAARWVAKSLVKAGLVKRCLVQVSYAIGVAEPLSISVFNFGT SKHSEKELLKIVKKNFDLRPGKIVKELDLQRPIYLKTAAYGHFGRPEFTWEQPKKLVFMA GSALKRLMAEYKQLTLNPPEGIIAGPVDEENFFEWEALITGPDETYFEGGVFPASLTFPP DYPLSPPKMKFTCDIFHPNIYNDGKVCISILHAPGDDPMGYESSAERWSPVQSVEKILLS VVSMLAEPNDESAANVDAAKTWRDNRPKFAEIAERTVKQSLGLXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMSSYTVVMIRHGESTYNKENRFCGWHDADLSEKGVEEAKIAGKTLKEKGFKFDIAFT SVLKRAIKTLNLTLEELDLDWIPVVKHWRLNERMYGGLQDLNKSETATKHGEEQVKIWRR SYAIPPPSLEVSDPRWPGHDARYADLDKNVIPRAECLKDTVERALPFWYDQIVPAIKNGK RVIISAHGNSLRAMVKYLDDISDDEIVGKNIPTGIPLVYELNGDLKPIKSYYLADEAAVK AAMDKVASQGKAKMEQENLFYNKPDYIETASGNKVSRQSVLCGSQNIVLNGKTIIMKDCI IRGDLANVRIGRHCVITSKAVIRPPFKKFSKGVAFFPLSIG------EGSVINAAQVGSY VHIGKNCVIGRRCVLKDCCAIADNTVLPPETVVPPFTLFSGSPGMSFLFGSRSNKTFKPK KNIPEGTHQYDLMKHAAATLGSGNLRLAVVLPEGEDLNEWVAVNTVDFFNQINMLYGTIT EFCTETSCPVMSASPKYEYHWADGQTVKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKI GVPFPKNFLTIAKTILKRLFRVYAHIYHQHFKEVIQLNEEAHLNTSFKHFIFFVEEFHMI ERKELAPLQELISKFT---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXDLKHEKFKGSYDVAATVQFLRKIVGNTKWSNAG ELIDLVKREGRILAQEVPTESATGNMVRRVLKIIREEYIMEAIGELLTELETSAQSLEHI HSNEVISTVEAFLKGKFQVIVVEFKGHELANSLAAAGIETTVITDSAVFAMMSRVNKVII GTHTVMADGGLKATGSHAIALAAKHYSVPLIVCAAMFKQSPQYLCSY-DSFNKFVSPHNI QNPLFDYVPPDLVTLYISNIGGNAPSYVYRLLSELYHXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRSPEAVEGRKHIDVQT ELYLEELSDRVEEADVDTQTDAFLDRPPSPMFIPAKTGVDIETQILEGELFDFDIEVKPI LEVLVGKTIEQSLLEVMEEEELANLRAQQRAFEELRNAELVEQQRLEEQERRHREEKERR MKQQREILRKEKETADKISARAFSQSYLADLVPSVFGTLSDNGYFYDPVERDCEQGFMPW LMDRVEEQLEKNVNGRTVLDGILRAVVQSRHEAFKKXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----EMAEFWKRNVKRPLSPLTVYKPEL TSMLSICFRICGIAMSVSVALMSCTLLALPHDFPHYVAALKDLQLPSSAYYGMKMFLCWP LIYHGMNGSRHLAWDAVWGFGLKTLYKSGWTVVASLPW------LSSYRDQHFKGSRTHQ EKLLLTSSTLYIGNLSFYTTEEQIYELFSRAGDIKRVVMGLDKVKKTPCGFCFVEYYTRV DAAMSMRYINGTRLDDRIIRSDWDVGFKEGRQYGRGKSGGQVRDEYRKDYDSGRGGYGII MKQKIKPGYTLKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGH KLGISDVAWSTDSRLLVSASDDKTLKIWELASGKCLKTLKGHSNYVFCCNFNPQSNLIVS GSFDESVRTGKCLKTLPAHSDPVTAVNFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG KWIVAGSEDNKIYIWNLQTKEIVQKLSGHTDVVLCCACHPTDNIIASAALENDKTIKLWR SDVMIIFKDILTGCELATDASNDLVYEFKAKDDSMIGGNKSSGYDVAIDDKKVYGSEVKK YMKRLQALQFYVHIVILEFETYVFQFFKDGLLEEK-MAVEFADGVIIGADSRTTTGSYIA NRVTDKLTKVTDTIYCCRSGSAADTQAIADIVSYHLNFHKMELGEEPLVKTAATTFKELC YSYRDSLSAGIICAGWDKKLGGQVYSIPIGGMLVRQPFSIGGSGSTYVYGHVDATFKEGM TRDECIKFVSNTLALAMFRDGSSGGIIRLAIITKDGVERQVILGNELPKF---------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------NEKFVFKVPYASIGAKTLVLAVYDFDRFSKHDRIGQIHVPLSSVD LGRVIEEWRDIGRPEAE-EKENKLGDICFSLRYVPTAGKLTIVILEAKNLKKMDVGGLSD PYVKLSLMLNGKRIKKKKTTIKKCTLNPYYNESFSFEVPFEQIQKVTL------------ ---------------------------------------------MVLADLGRKITTALR SLSNATIINEEVLNSMLKEICKALLEADVNIKLVKQLRENVRSVIDFDEMAAGLNKRRMI QSAVFKELVKLIDPGIKAWTPTKGKNNVIMFVGLQGSGKTTTCTKLAYYYMKKGWKTCLI CADTFRAGAFDQLKQNATKARIPFYGVDTSGRHKQEDSLFEEMLQVSNVSPDNTVFVMDA SIGQACENQAKAFKEKVDVASVIITKLDGHAKGGGALSAVTRSPVIFIGTGEHIDDFEPF KVQPFVSKLLGMGDIEGLIDKVNELKLDDEELMKKLRH---------------GQFTLRD MYEQFQNIM----------------KDCVAIAADRRFGVQAQTVSMDFQKIFEIGPTLYV GLPGLATDVQTIAQKLKFRTNLYELRENRKMKPKTFLSVVSNLLYERRFGPYFVEPVVAG LDPNTSEPFIASLDLIGCPMITEDFVVSGTCSEQMYGMCESLWEPDMSPDDLFETISQAL LNAVDRDAVSGWGAIVHIIEKDKVTTKTLKARMDMTSKDYYFDSYAHFGIHEEMLKDEVR TLTYRNSMYHNRHLFKDKVVLDVGSGTGILCMFAAKAGAKKVIGIEMSSIVEHSKKIIEL NKLSDVITIIKGKVEEVVLPDGIDKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPDGM IFPDRATLYVCGIEDREYKEDKINWWDNVYGFDMSCIRSVAISEPLVDVVDHKQVVTNSC LLKEVDIYTVKEGDLSFEAPFHLQCRRNDYVQALVTFFNIEFTKCHKRVGFSTAPEARYT HWKQTDDYITIKKGEEMFGTFKMTPNSKNNRDLDFDISVDFKGELSNTTSNMTFKMRMVR EDKATWKANYFLKIIQLLDEYPRLFIVGADNVGSKQMQNIRQFMRVLMGKNTMMRKAIRG HIENNPGLEKLLPYIKGNVGFVLTKDDLTDVRDRLLQNKVAAPARAGAIAPIDVKIPAQN TGLGPEKTSFFQALSIPTKISRGTIEILNEVHLIKEGSKVGASEATLLNMLKISPFSYGL IIQQVYDSGTVFSPSILDITNEDLLRRFMEGVRNIAAVSLSIGYPTVCSVPHSIVNGFKN LLAIAAVTDISFKEAETLKESAKSGKLLAVIGDEDTCTGFLLGGIGELNKHRHPNFMVVD KSTSVSEIEDCFNAFKS----------------XXHVLDAHTDPTPAVLEIPSKDHPYDA NKDSILRRAKGMFSAEDLRGNETSLPMELCSTFDADEIKRLGKRFKKLDLDNSGSLSVDE FMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIDGMSKVSAKGDKVAKLAFAFKIYDMD KDGYISNGELFQVLKMMVGSNLKDAQLQQIVDKTIIHADADGDGKISFEEFCSVVGTMDV HKKMVVDIMTYITSWDDFSKAAEKLYLSDPMKCRYVIKYINKDGTLNIKVTDDNMVLQYR TQHAQDVKKLEKLTSLLMRHMASKE----------AREREKYDNMADLFAVINTLQCLEK AYIKDSVTPKEYTAACSKLLVQYKSAFKQVQGDDYPTIEVFMKKLKMDCPAALERIKEDR PITIKDDKGNTSKCIADIVSLFITIMDKLRLEIRAMDEIHPDLKELAETMNRLSLLPAEF EGKTKVNSWLGTLNSMQASDELTDAQVRQMLFDLESSYNAFNRILHSXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------- ----------------------------------------------QHRGKRVVFLKQLA SGLLLVTGPYHLNGCPLRRINQQYVIATKTKLD--------------------------- ----DTKKEVYKVSDERKADQVDVDKQVLDAIRKNSEKKYLFGYLGAMFSLEGKNYPHNM VFLEWLFGRKKTPEEMLRQNQRALNRAMRDLDRERSKMEQQEKKVINDIKKMAKEGQMDA VKIMAKDLVRTRRYVKKFILMRANIQAVSLKIQTLKANNSMATAMKGVTKAMQRMNAQLK LPQIQKIMMEFEKQSEIMDMKEEMMTDAIDDALGDEDDEEEGDAIVSQVLDELGLQLGDK LSDIPTTGGS-AKQPVPVSDADADLEARLENLRRQ-KYCDFCLGNEMKNEKTGGPEELVS CGDCGRSGHPTCLQFTANMIVSVKKYPWQCIECKSCGLCGTSDNDDQLLFCDDCDRGYHM YCLKPPLSEPPEGSWSCHLCIEEFHG---KPINLYPLTNYTFGTKEPLYERDKSVEARFS RMREEFAKIGMRRSVEGVLIVHEHGLPHVLLLQLGTTFFKLPGGEVNQGETEVDGLKRLL TETLGRQDGAPMDWLVEETIGNWWRANFEPPQYPYVPAHITKPKEHKRLFMVQLPEKALF AVPRNYKLVAAPLFELYDNSAGYGPIISSLPQALSRFNFIYNFTPSGVTPSGAKAMAMAT PTPGHLMSMTPEQMQAYTWQREIDERNRPLADEELEAMFPPGYKVLNPPAGYIPIRTPAR KLVATPTPMAGTPMGFRMQ------------------------RKIMKFLLKIKNGTPPM RKAALRQITDKSREIGAGALFNQILPLLMSPTLEDQERHLLVKVIDRILYKLDDLVRPYV HKILVVIEPLLIDEDYYARVEGREIISNLAKAAGLATMISTMRPDIDNMDEYVRNTTARA FAVVASALGIPSLLPFLKAVCRSKKSWQARHTGIKIVQQIAILMGCAILPHLKNLVEIIE HGLVDEQQKVRTITALALAALAEAATPYGIESFDSVLKPLWKGIRQHRGKGLAAFLKAIG YLIPLMDAEYANYYTREVMLILVREFQSPDEEMKKIVLKVVKQCCATDGVEPQYIKDEIL PPFFKHFWNQRMALDR-------------------------------------------- ----------PDIDSRLEEQLIDGILYAFQEQTTEDVVMLNGFGQVVNSLSKRVKPYLPQ ICGTILWRLNNKSAKVRQQAADLISRIAVVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLG SILGALKAIVNVIGMTKMTPPIKDLLPRLTPILKNRHEKVQE------------------ ----------------------RRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVC TTVAIAIVAETCSPFTVLPGLMNEYRVPELNVQNGVLKSLSFMFEYIGEMGKDYIYAVSP LLEDALMDRDLVHRQTSMSAIGHIALGVFGFGCEDALTHLLNHVWPNVFESSPHVVQAFM SSIEGMRVGLGPSRVLQYALQGLFHPARKVRDVYWKVYNTVYIGAQDSMIPAYPRVYNDD KNNYLRYELDYMLDDFMVDDEEYDLEYSEDSNSEPDVDLENQYYNSKASKEDDPKAALES FQKVLDLEGTEKGEWGFKALKQMIKINFKLNNYTEMMNRYKQLLLYIKSAVTRNYSEKSI NSILDYISTSKQMTLLQNFYETTLEALREAKNDRLWFKTNTKLGKLYFDREEYMKLQKIL KQLHQSCQTQDGEDDLKKGTQLLEIYALEIQMYTEQKNNKKLKTLYEQSLHIKSAIPHPL IMGVIRECGGKMHLREGEYEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGIN PFDSQEAKPYKNDPEILAMTNLVSAYQNNDINEFEKILKTNRKNIMEDPFIREHIEDLLR NIRTQVLIKLIKPYTRIHIPFISKELNIDVTEVESLLVSCILDNTIHGRIDQVNQVLELA QGIARYSALDKWTAQIHSVHQAIINKIAVLLMGKSGSGKTSMRSIIFANYIARDTRRLGA TIDVEHSHVRFLGNLVLNLWDCGGQEAFMENYFASQRDNIFRNVEVLIYVFDVESRELEK DMHYYQSCLEAILQNSPDAKVFCLVHKMDLVQEDQRELIFREREEDLKRLSKPL------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------NITIDIRNVCVFLAPIFSSLTA LITFVLTKEIRDVGSGLVAASMIAIVPGYISRSVAGSYDNEGIAIFCMLFTYAMWIKSVK TGSLFWAVICSLAYFYMVSSWGGYVFLINLIPMHVLALMATGRFSHRIYVAYCTVYSIGT LLSMQISFVGFQPIQSSEHMAALGVFGLCQIHAFVDYVRSKLTREQFDTLFRAITLLVGI IILTASGKVAPWTGRFYSLLDPSYAKNNIPIIASVSEHQPTTWSSFYFDLQFLVFLFPAG LYFCFTKLTDANIFIILYGATSIYFAGVMVRLMLVLAPVMCILSGIAVSATLSTYMKNLD AVQRGDQNYPVKNEVATGVVFMVTAFLIMYSFHCTWVTSEAYSSPSIVLSARGGDGGRII FDDFREAYYWLRHNTPEDAKVMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMAS TEDKAYEIMRELDVDYVLVIFGGLTGYSSDDINKFLWMVRIGGSTDRGSHIKESDYYTPQ GEFRIDKDGSKTLLNCLMYKMCYYRFGAVYTEQGKPTGYDRVRNAEIGYKDFELDVLEEA YTTEHWLVRIYKVKDLVN---KLNIRPLMRIICRRFFGDFNGFVQMCVDHIPSPLDNAKN KVKHLYTGTDDTDLTDAMFECDPDGPLMVHTTKLYPTDDATTFHAFGRVISGTLSANQDV KVLGENYSLQDEEDSRFAVVGRLWISEARYKIELNRVPAGNWVLIEGVDQPIVKTSTITD ATGNEEAHIFRPLKFNTSSVIKIAVEPVNPSELPKMLDGLRKVNKSYPLL---------- ----------------------------------FCETVVETSSLKCFAETPNKKNKITM IAEPLEKGLAEDIENEVVQISWPRKRLGEFFQTKYDWDLLAARSIWAFGPDATGPNILVD DTLPSEVDKALLSSVKDSIVQGFQWGTREGPLCDEPIRNCKFKILDAVIAQEPIHRGGGQ IIPTARRVAYSAFLMATPRLMEPYNFVEVQAPADCVSAVYTVLARRRGHVTQDAPVPGSP LYIIKAFLPAIDSFGFETDLRTHTQGQAFCLSVFHHWQIVPGDPLDKSIVIRALEPQPAT ALAREFMVKTRRRKGLSEDVSINKFFDDPMLLELAKQDVMLNYPMXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--- ------------------------------------------------------------ ----DDKLKEKMVVEFQHIRNQALEPLSTFLDYVTYSYMIDNIILLITGTLHQRSISELI PKCHPLGSFEQMEAIHIAS----------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------SPRKAIRKISKIPFK VLDAPELQDDFYLNLVDWSSQNVLSVGLGTCVYLWSACTSQVTRLCDLSCDGDSVTSVSW NERGNYVAVGTHKGFVQIWDAAASKKISTLEGHSARVGALAWNADMLSSGSRDRLILQRD IKTPSSMPERRLQGHRQEVCGLKWSPDHQHLASGGNDNKLFVWNMNSCQPIQTYTEHLAA VKAIAWSPHQHGLLASGGGTADRYMRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVST HGYSQNQILVWKYPSLVQIAKLTGHSYRVLYLATSPDGEAIVTGAGDETLRFWNVFSKTR STKESKSVLNMFTSIR---IVGLYYILSGQGHRFDIGWFLEGTSPFMWGAMGIGLAISLS VVGAAWGIYTTGASIIGGGVKAPRIKTKNLISIIFCEAVAIYGIIMAIVISNQTNYFAGY AMFAGGLTVGLCNLFCGICVGIVGSGAALADAQNGSLFVKILIIEIFGSAIGLFGVIVGI LQTTRAKM---MAATRRLTKELGDKVDESNILNWQALLTPDQPPYNKGAFRIEINFPAEY PFKPPKITFKTKIYHPNIDEKGQVCLPIISPENWKPATKTDQVIQALVSLVNEPEPEHPL RGDIAEEYTKNKKLYLKSAEDYTKKYSEKRPSDGASKCIPQQCSALRKGGFVLIKEKPCK IVEMSTSKTGKHGHAKVHLVGIDIFTAKKYEDICPSTHNMNVPKVSRTEWQVVDIDDNSV QLMDDAGNLKEDLFVPATVLQAMDSETIIDCKIAKGKLLGPKGVTIDNNGHIIVVDNKAS -------------------WHNFAGPHFVAVNTQNDIIVSDFHNHCIKVFDEGEFLFSFG SNGVGNGQFNAPTGVAVDSLGNILVADWGNSRIQVFDSQGSFLSYINLYGPQG------- ------------------MAAGPIAERNQDATVYVGGLDDKVSEAILWELFLQAGPVVNV HMPKDRVTQSHQGYGFVEFLGEEDADYAIKIMNMIKLYGKPVRVNKASAHQKNLDVGANI FIGNLDPEVDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGFAFINFASFETSDAAIEAM NGQYLCNRAISISYAFKKDSKGERHGSAAERLLAAQNPLSQADRPHQLFADAPPAHQPIG AAPPPPPPMGQGPPGGPPNMPPGGMMPPPMPPPGNLPPPPMPPPPPPPQQPGPPPRM--- PPMPPPPGMRPPPGMRPPPGKVEPKKVVNPLFERRPKNFGIGQDIQPKRDLRRFVKWPKY IRLQRQKAVLVKRLKVPPTINQFRTTLDRQTATNMFRLMDKYKPETKQAKKQRLAKRAEE RVKGKDDEPTKRPPCVRSGVNTVTTLIEQKKAQLVCIAHDVDPIEIVLFLPALCRKMGVP YCIVLGRVVGRKTATCLALAQVNSEDRSALNKLVESVKTNFNERADEIRKHWGGGIMGSK SQARIAKFDKVKARELAQKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--ITRIVAR QIFDSRGNPTVEVDLQTGKGTFRAAVPSGASTGIYEALELRDQDPAAYHGKGVSQAVGHI NNSLGPALIVDVTQQKEVDQVMLDLDGTENKSKFGANAILGVSLAVAKAGAAAKGVPLYR HLADLAGNKDVILPVPAFNVINGGSHAGNKLAMQEFMILPTGAKNFTEAMRMGSEIYHHL KKVIKAKYGQDACNVGDEGGFAPNIQVNDEALKLVTTAIAKAGYEGKIKIAMDIAASEFY KKYDLDFKSKDSDQSKWLTSDALGEIYKDFIANYPVVSIEDAFDQDDWKAWSKLQSIQLV GDDLTVTNPKRVQTAIDSKACNCLLLKVNQIGSVTEAIDACKLSQTNGWGVMVSHRSGET EDSFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGANAKYAGENFRKPGSPHK AGAFKPRHTTPTQFRKCYERGDFPIALEHDTKGNKIAWKVEIEKLDYHHYLPLFFDGLRE TTHPYEFFARQGVHDMLEHGGSKILPVIPQLIIPIKNALETRTPKVLCTTLKVMQHLVVS GEHIGEALVPYYRQILPVLNIFKSKNLNTGDGIDYSQQRRENIGDLIDETLTAFEKHGGE D----------------------------------------------------------- -------------------------HKIVVRIQTTSDYSPMEAFTNAITDLISEISLLEE RFRDAVREKQETEEDHRRKWDKAEYEKVAKERLEKEAGKKEKPVKRELLKPREYKVDLDS KLGKSSVITKTTPSSQQGGYYCNACDCVVKDSINFLDHINGKKHQRNLGMSMRVERSSLD QVKKRFEANKKKMEEKKKDYDFEERMKELKEEEEKQRAYRREKRKAQKRKADDTNMDPDM AALMGFSGFGSSKK---------------------------------------------- -----------------------------NLLQSMKYVLTGMGLLRINLENPQNKVHAET VLACNKCTDSDHQVFPYISHAIQCLWLDRGIKLAASRGYEFELNDSATYYFENMSRICSK DYIPNSKDVLRARVRTQGIIETCFKIHEYIFRLFDVGGQRSERKKWIQCFDDVRA----- ------------------------------------------------------------ ---------------------------------------------------------YHS QFKDAPQNIGNMAMCPIKTQFKGPAFDIIDEAIQFFKANVFFKNYEITSEADRTLIYITL YITECLKKLQRCTSKNNGLKEMHSLAIQKFDIPGDSGFPLNSLYTKPKNRGEEDTMKQFI LQLRQETGLRVVEKVFDPQTDKPSKWWMCFVKRKFMDKSLSHPG-AGPYNYSYIFKYIII GDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVT RSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIFLIGNKSDLDGQRDVTYE EAKQFADENGLMFLECSAKTGENVEDAFLDTAKKIYQNIQDGSLDLNAAESGVQHKPTAP RNAINTDQPAAKEGCSC-------------IKGTVDFRQMAATEIKVSLQGFANIYHGFH VHGTGDLSNGCQSTGGHYNPFSKTHGAPSDSERHVGDLGNIMEDQTTITDSQVSIVGTYS IYGRAIVVHQKRDDLGRGGDAGSKATGNAGGRLACCIIG---MVNFTVDEIRAIMDKKNN IRNMSVIAHVDHGKSTLTDSLVSKAGIIAGAKAGETRFTDTRKDEQERCITIKSTAISLF YAVAEKDLGNEFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQA IAERIKPVLFMNKMDLALLTLKLDMEDLYQKFVKTVENVNKIIAIYSEEDGPMGSIYVEP GKGNVGFGSGLHGWAFTLKQFAEIYASKFDIDTPRLMKRLWGDQFYNAVRGFTQYILDPI YKVFNFCMPKEDALK------------------------------------LXXXXIHLP SPVTAQKYRMEMLYEGPHDDAAALGIVNCDPEAPLMMYISKMVPTSDKGRFYAFGRVFSG KVATGLKTRIMGPNFTPEKSIQRTILMMGRYTEPIEDVPCGNICGLVGVDQFLVKTGTIT TLKEAHNMKVMKFSVSPVVRVAVEVKNPSELPKLVEGLKRLSKSDPMVQIYTEESGEHII AGAGELHLEICLKDLEEDHAGVPLKKTDPVVSYRETVQERSSQICLSKSPNKHNRLFLSA GPLDDGLPEDIDSGEITPRQDFKLRGRYLIDKYSWDATESRKIWCFGPEGTGPNLLVDVT KGVQYLNEIKDSVVAGFQWATKEGVLCEENMRGIRFNIHDVTLHADAIHRGGGQIIPTAR RVLYASALTAKPCLMEPVYLCEIQCPEAAIGGIYSTLNKRRGIMLEENQVPGTPMFQIKA HLPVNESFGFTGALRQATGGQAFPQCVFDHWALYVVTLTRKRKGLKEEIPPLDKYLDKMM LPLSLLRTAVNHPMLVELKNGETYNGHLVNCDNWMNINLREVICTSRDGDRFWRMPECYI RGSTIKYLRIPDEVIDMVKEEVQQKPRGQGGMRQRGRGG-GRGAFGGRGG----GGRGGG GG-NEFKLNNSPTDGISAVKFGPNSSQFLLVSSWDCYVRLYDVVSNSLRIKYGHTEPVLD CCFQDTVHAYSGGLDNSLKMYDFNTSAETHVGSHDGAVRCVEYAPDTNVVITGSWDFTVK LWDPRAPTCTGSYSQPDKVYTLAVTGDRLVVGTAGRRVLVWDLRNMGYVQQRRESSLKYQ TRCIRTFPNKAGFVLSSIEGRVAVEYLDPSPEVQKKKYAFKCHRVKEDGVEKIFPVNAIA FHNTHNTFATGGSDGFVNIWDGFHKKRLCQFHRYPTSIASLAFSQDGSTLAIASSYMYEQ DPPDDNVYIRHVSDQETKPKMDFQHRAGGKTGTGGVASASESNRDRRERLRQLALETIDL NKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQANLARRAAKEAKDAPAQPAPE KARVDIKKFVKIGRPGYKVTKQRDPDNNQQSLLFQVDYPEIVEGIAPRHRFMSAYEQKVE PPDRKWQYLLFAAEPYETISFKVPSREVDKDPKRFWSHWNKETKQFFLQFAFKAEPK-PN RGPGVGDGPPGVMDDEADTIKLWRIRKTIMQLCHDRGYLVTQDELDQTLDQFKQQFGDKP SERRPARSDLIVLVAHNDDPTDQMFVFFPEEPKVGIKAIKTYCQRMQEESITKAIIIVQN GMTPSAKQSLTDMAPKYILEQFLEAELLINITEHHLVPEHVIMTPEEKKELLERYKLKES QLPRIQQGDPVARYFGLKRGQVVRIVRPSETA----------EDKDSVGTVIGIDLGTTY SCVGVFKNGRVEIIANDQGNRITPSYVAFTSEGERLIGDAAKNQLTSNPENTVFDAKRLI GRTWSEPSVQHDLKYFPFTVMEKNSKPHVKVAMGDEQKIFAPEEISAMVLGKMKEVAEAY LGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLNVMRIINEPTAAAIAYGLDKKEGEKNI LVFDLGGGTFDVSLLTIDNGVFEVISTNGDTHLGGEDFDQRVMEHFIKLYKKKKGKDIRK SNRAVQKLRREVEKAKRALSSQHQTRIEIESLYDGEDFSETLTRAKFEELNMDLFRSTMQ PVKKVMEDGDLSKNEVDEIVLVGGSTRIPKVQQLVKEYFNGKEPSRGINPDEAVAFGAAV QAGVLSGEDDTGDLVLLDVNPLTMGIETVGGVMTKIIPRNTVIPTKKSQIFSTAADNQPT VTIQVFEGERPMTKDNHLLGKFDLQNIPPAPRGVPQIEVTFEIDANGILKVSAEDKGTGN KEKITINNDQNRLSPEDIERMINDAEKYAADDEKVKSKVEARNELESYAYSLKNQVGDKE KLGAKLSDEDKEKITEALDEKIKWLEANQEAEAEDFKTQKKELEDIVQPIMSKLYADAPP PEGEQEQEK--------------------------------------------------- --------------------------------------KGFSYVEFGDLESLKEALAYDG ALFGERSLRV-------------------------------------------------- ----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXX-KVGINGFGRIGRLVLRSALEKVDVVAVNDPFIELDYMVYMFKYDXXH-- -------------XAVFNEMAPTNIPWKKAGAEYVVESTGVFTTIEKAKAHFEGGAQKVI ISAPSADAPMFVMGVNQDKYEKSMNIVSNASCTTNCLAPLAKVINDNYGIEEALMTTIHA YTATQKTVDGPSSKAWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPVPDV SVVDLTVRLSKPATMDDIKAKVKGPMKGFFGYTDEQVVSQDFRGDSNSSIFDARAGIQLS PTFVKLITWYDNEYGYSCRVCDLINY----------TAILKKKDRPNRLLVEEAINEDNS VVSLSQAKMDELQLFRGDTVLLKGKKRRETVCIVLSDETVSNEKIRINRCVRANLRVRLG DVVSIQACPDVKYGKRVHVLPIDDTVEGLTGNLFEVYLKPYFLEAYRPLKKGDVFIVRGG MRAVEFKVIETDPSPYCIVAPDTVIHCEGEPVKREDVEDSLNEVGYDDIGGCRKQLAQIK EMVELPLRHPQLFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSK LAGESESNLRKAFEEAEKNSPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQ RSHVIVMAATNRPNSIDGALRRFGRFDREVDIGIPDATGRLEILRIHTKNMKLA------ ------------------------------------------------------------ ----------------------------------------------------PSRGVLFY GPPGCGKTLLAKAVASECSANFVSIKGPELLTMWFGESEANVREVFDKARSAAPCVLFFD ELDSIGTQRGGSVGDAGGAGDRVMNQLLTEIDGV-------------------------- ------------------------------------------------------------ ---------------------------EITRKHFEEGLTGARRSVSTTDLAKYDNF---- --------GQNTSFGGTSVFGATSNYNPMKDVEVTSPPDDSVSSLAFSPASCPSTFLVAG SWDNNARCWEVQANGNTTPKAQQTHTGPVLDICWSDDGTKVFTASADKQAKMWDLNTNQA VQIAQHDAPIKTIHWVKAPNYTCVMTGSWDKTLKFWDTRSPNPMMSIDLPERAYCADVLY PMAVVGTANRQLVIYQLENQPSQFKVIDSPLKYQHRCVSIFNDKKNNSPVGFALGSIEGR VAIHYVNPTNPKDNFTFKCHRAGVQDIYAVNDIAFHPVHGTLSTVGSDGRFSFWDKDART KLKTSEQVDQPISACAFNAQGQIFAYTSSYDWSKGHEGFDPQKMKPRIFLRSCYDELKPS KKKMSSPSPGKRRMDTDVVKLIESKHEVTILGGLNEFIVKFYGPNSTPYEGGVWKVRVDL PEKYPFKSPSIGFMNRIFHPNIDEVSGTVCLDVINQAWTPLYDLSNIFDSFLPQLLTYPN PIDPLNGDAAAMYLHKPEEYKKKVTEYVKKYATEEAIRECESSMSDFSEDEAQDMEL--- ------------------KSSLLLRFTDDTFDPEQAATIGVDFK-------------XXW DTAGQERFRTLTPSYYRGAQGVILVYDVSSKQSFTKLDAWLSELETFATKHEIVKMLVGN KIDKDKREVSRDEGLKFARKHHMLFIEASAKTKEGVQCAFEELVEKIIQTPGLWETDGVR LGT-------------------------------------CPLANSQYATVREEKGVAYL YMKTIERAAFPDRLWEKVKLSKNFEKALQQIDEHLIYWPKYLRHKCKQRYTKITQYLIRI RKLTLKRTKKLVPLQRKIERRERRREEKALVAAQLDNAIEKQLLDRLKQGTYGDIYNFPQ HAFDKAVEEEEVSEESEDEEEIEYVAEEEFEESDVSDIE------QVQPKLKKFSIYRWN PDKAGDKPHVQTYEVDLNKCGPMVLDALIKIKDTIDPTLTFRRSCREGICGSCSMNINGG NTLACLCKIDDNTSKAMKIYPLPHMYVVKDLVPDMSNFYAQYRSIEPYLKKKDIDEKDIG KVPYSQSPEDRAKLDGLYECILCACCSTSCPSYWWNGDKYLGPAVLMQAYRWLIDSRDDF TMERLSRLQDKWSVYRCHTIMNCTKTCPKGLNPGLAIGEIKKML-----------DIRPN NTIYINNLNEKIKKEELKKSLFAIFSQFGQILDIVAAKTLKARGQAFVIFKEVTSATSAL RSMQGFPFYDKPMRIAYSKKDSDIIAKMKGTFVERPKKQKKVSGKRKKQKAGPTAMPEQP PNQILFLTNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENEMQAAAAKDALQ GFKITPSNAMKISFAKKMDSQGRKVVVCDNGTGFVKCGFAGSNFPEHIFPSLVGRPILRS TAKIGNIEIKDLHVGDEASQLRSMLEVNYPMDNGIVRSWEDMLHIWNYTFGPEKLNVDPK QCKLLLTEPPMNPMKNREKMIEVMFETYQFEGVYIAIQAVLTLYAQGLLTGVVVDSGDGV THICPVYEGFALPHLTRRLDIAGRDITKYLIKLLLLRGYAFNHSADFETVRMMKEALCYV GYDIEQEQKLALETTVLVEQYTLPDGRVIKVGGERFEAPEALFQPHLINVEGHGVAELLF NTVQAADIDTRAEFYKHIVLSGGSTMYPGLPSRLEREIKQLYLERVLKGDTEKLSKFKIR IEDPPRRKHMVFLGGAVLADIMKDKDSFWMTRLEYEEKGLRVLEKL-------------- -----------------------------KVTATGVCHTDAYTLDGFDSEGKFPVILGHE GGGIVESVGEGVTSVQPGDHVIPLYIPQCKNCKFCNSPKTNLCGKIRTTQGQGQMPDGTT RFTCKGQEVFHFMGTSTFSEYTVVAEISVAKV---------------------------- ------------------------------------------------------------ --------MTDGGLDYTFECIGNVGTMRAALESCHKGWGVSTIIGVAAAGQEISTRPFQL VTGRVWKGTAFGGFKSRDSVPKLVEDYLGGIVKVDEFI---MPLDKINESFDLMHAGKS- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------AMQHSIM RVDIAGRDVSRYLRLLLRKEGHNFHTSAELEIVRTIKERACYLSINPQKEETMDTEKTAY TLPDGSTLEVGPARFRAPELLFRPDLIGEEYEGIHDVLHYAIQKSDMDLRRVLYQNIVLS GGSTLFKGFGDRLLSEVKKLAPKDIKIRISAPQERLYSTWIGGSILASLDTFKKMWVAKR EYDEEGARAIHRKTFEAPKVAKVVVHPLVLLSVVDHFNRMGKVGNVKRVVGVLLGSNRQG ILDVSNSFAVPFDEDDKDKTVWFLDHDYLEMMYTMFKKVNARERIVGWYHTGPKLHENDV LINEVMRRYCPNSILVIIDAKPKDIGLPTEAYIAVEEVHDDGTPTTKTFEHVASEIGAEE AEEVGVEHLLRDIKDTTVGSLSQRVTNQLLGLKGLHQQIQGIHSYLEQV----LPINHQI IYQLQDVFNLLPDVNLTEFVKSMYVTTNDQRLVIYLSSLIRSIIVLHNLIDNKLSNKEAE KGDGDSKKMGLLFTKLWSFFTNEEHKVIIVGLDNAGKTTILYQFLMNEVVHTSPTIGSNV EEVVWKNIHFLMWDIGGQESLRSSWNTYYTNAEFIILVIDSTDRERLMITREELYRMLSN EELRKAAVLIFANKQDIKGCMSPAEISQQLNLTSIKDHGHHIQACCGLTGEGLYLGLEWI ANQLKRKAIPSRRIALHSPSQLPADYSSTPGGTLFSTTPGGTRIIYDRSFLLGCRNSPLA KSPPPNLPKIPGVTSPPPPGKRKEIYKYEAAWNIYSMNWSVRPDKRFRLAVGSFVEEYNN KVQIVSLDEETSDFAARSTFDHPYPTTKIMWIPDSKGVFPDLLATSGDYLRVWRATRLEC LLNNNKNSDFCAPLTSFDWNEVDPNLLGTSSIDTTCTIWGLETGQVLGLVSGHVKTQLIA HDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLAWNKQ DPNYLATMAMDAMEVIILDVRVPCTPVARLNNHKACVNFISWAPHSSCHICTAADDHQAL IWDIQQMPRAIEDPILAYTASGEINQVQWSTTQPDWIAIGYNNCLEILRVXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXIDRGKDFNIKTRIITDGLKYSLATGNWGDQKKAHAARAGVSQVLNRLTFAS TLSHLRRLNSPIGRDGKLARPRQLHNTLWGMICPAETPEGQAVGLVKNLALMAYISVGSQ PSPILEFLEEWSMENLEEISPSGIADATKIFVNGCWVGIHRDPEQLMSTLKKLRRQMDII VSEVSMVRDIRDREIRIYTDAGRICRPLLIVENQKLLLKRSHINNLKEREYNNYSWQDLV ASGVVEYIDTLEEECIMVAMTPDDLQDKSSAYCSTYTHCEAHPSMILGVCASIIPFPDHN QSPRNTYQSAMGKQAMGVYITNFHVRMDSLANVLYYPQKPLVTTRSMEYLKFRELPAGIN TIVAISTYTGYNQEDSVILNESAVDRGFFRSVFYRAYKDAESKKGFDQEEVFEKPNPDTV LGMRPSMYDKLEDDGIIAPGIRVSGDDMLLGKTLTLPEQDDELESTARRYTKKDASIGMR RSEYGIVDQVMITINSDGYKFCKI------------------------------------ --------------------------------------------FNDTVNVQKISKLLQE YGYHQRGNEVMYNGHTGRKIVSQVFLGPTYYQRLKHMVDDKIHSRARGPLQILNRQPMEG RSRDGGLRFGEMERDCQIAHGAAQFLKERLFEASDAYRVHVCNLCGLICIANLRNQTFEC RGCKNKTQISQVKMPYACK----------------------------------------- ------------------------------------------------------------ --------------------------------------YQGHISAALVLGGVDNTGPHLY SVYPHGSTDKLPYVTMGSGSLAAMSVFEDGYKPDMEMEDAMKLVRDAIAAGIFNDLGSGS NVDLCVIKKKVDYLRPYDEANQKGIRQGKYTYKRGTTGVLTSEVK-------MSKVTFKI TLTSDPKLPYKVLSVPEQTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPAQNAGNVFL KHGSELRLIPRDRVG-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHSKKKICYYYDGDIGN YYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATQEEMTKFHSDDYIKFLRSIRP DNMSEYNKQMQRFNVGEDCPVFDGMYEFCQLSTGGSVAGAVKLNKQAADIAINWGGGLHH AKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY GEYFPGTGDLRDIGAGKGKYYAVNFPLRDGINDESYEQIFQPVMCKVMEMYQPSAVVLQC GADSLSGDRLGCFNLTLKGHGKCVDFMKKYNLPLLLLGGGGYTIRNVARCWTYETSIALG VDVANELPYNDYFEYYGPDFKLHISPSNMANQNTTEYMDKIKTRLFENLRMLPHAPGVQM QNIPEDAINDERKPDERVSIRATDKRITDDGVYSDSEDEGEDGRRDRQSFQRKKLDSGEY ECNICLDTAKDAVVSMCGHLFCWPCLHQWLETRPNRQTCPVCKAGISRDKVIPLYGRNNA SREDPRDKAPPRPQGQRSEPENNGAFPGFNFGFQMSFGIGAFPFGFFASNFNMGDTRPPA PGPETPQAAEEQFLSKVFLYVAMLFIFWLLIAQHSLIYKTELAHDDSIWTCAWNRNDKEN TENIVTGGVDDKVKIWRWADLELKHTLDGHQLGVVSVDINATGTLAASSSLDSHIRIWDI EAGKQAKSIDSGPVDAWTVTFSPDTRFLASGSHTGKINLFGVDSGRKESSLDTRGKFVLS IAYSPDGRYIASGAIDGIVNIFDMTTGKLLEGHAMPIRSLCFSPDSQLLVTASDDSHIKI YDVQHANLAGTLSGHGSWVTYVSFSPDNTHFVSCSSDKTVKVWDSGSRHCMHTFYDHADQ VWGAKYNSTGTKIVSVSDDKCVHIYDAAVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXX------------------------------------ ---------------------------KEHMGRRYIEVFRSKRSEMEWVVKRSGQGADAV VRLRGLPFGCTKEEIAHFFSGLEIAPNGITIVQDRPGKSTGNAYVQFTSPQLAEQSLSKH KEQIGHRYIEIFKSSLNEARA------------------AIEQDIIDFFSPMQPVNVCLK YLDGRASGECDVDFATHEDAKDAMKKDKAMMEHRYIELFYQDKDKPAQIRGSNITAAKAV ADAIRTSLGPRGMDKMIQASNGDVTITNDGATILKEMKVLHPAAKMLVELSKAQDIEAGD GTTSVVVIAGSLLDASAKLLAKGIHPTTISESFQGAAQKSCEILEKIATPVDLSDREVLL KNASTSLNSKVVSQYSSIISPIVVDSILRVTDIAKDTNVDLRDIKIVKKLGGTVEDTELI DGLVFTQKTSGAGGPNKVEKAKIGLIQFCISPPKTDMENQVVVSDYTQMDRVLREERQYI LNIVKQIKKSGCNVLLIQKSILRDAVSDLAEHFLAKMKIMLIKDIEREDIEFICKSIGCK PIASLDHCTADMLGSAELVEEIQTGSSKVVKVTGVLNPGQAVSVIVRGSNKLVLEEADRS IHDALCVIRCLVKKRALISGGGAPETEVALALHEYSLSLSGMEQYCYRAFADALEIIPFT LSENAGLNPIATVTELRNRHAKGEKSAGINVRKGAITNILEENVV--------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------RVTVVFSTVFK DDDDIIIGKVFLQEFKEGRRKFQQAPQVLFSHKEPPSELKGTDAA----------VXXPR HESKDNTINLIHTLRDYLHYHIKCSKAYIHSRMRAKTVDFLKVLNRARPEQK-------M LMFCPTCGNVLVVEEGPSCYRFGCNTCPYIHNINKKMSSRKYPKLKDVDDVLGGAAAWEN VDSTEETCPKCEHNRAYFMQIQTRSADEPMTIFYKCCNAQCGHRWR-------------- ------------------DWYKTKEICEKGVDWILKEITKSGLRGRGGAGFPTGMKWGFM NKPDDGRPKYLVVNADEGEPGTCKDREIMRHDPHKLVEGCLVAGRAMGARAAYIYIRGEF YNEASNLNIAVQEAYQAGLIGKNACNSGYDFDVYVHRGAGAYICGEETSLIESLEGKAGK PRLKPPFPADVGVFGCPTTVANVETVAVAPAICRRGGDWFASFGRTRN-DVMMDFDALVQ VQTGLGTAAIIVMNKQADIVKCIARLMEFYKHESCGQCTPCREGTGWMVKLMNRFVTGEA KPDEIDMLYELSKQIEGHTICALGDGAAWPVQGLIRHYRPELLRRMEDFQKSQFTQEQVD DMNTQLNQTRSQRVRAAMFPETLEDGIQIPSTQIHPDQPTAVQRLAEPSQMLKHAVVNLI NYQDDADLATRAIPELTKLLNDEDQVVVSQACMMVHQLSKKEASRHAIMNSPQMVAALVR AMGNSNDVETIRCAAGTLHNLSHHRQGLLAIFKSGGIPALVKLLSSPVESVLFYAITTLH NLLLHQEGSKMAVRLAGGLQKMVILLQRNNVKFLAITTDCLQILAYGNQESKLIILASGG PGELVRIMRSYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALAMHLGHQSQRLVQN CLWTLRNLSDAATRCENLEGLLQMLTQLLASNDINIVTCAAGILSNLTCNNQRNKVTVCQ LGGIEALVRTILQAGDREEITEPAVCALRHLTSRHPEAEMAQNAVRLHYGLPVLVKLLHP PSRWPLIKAVVGLIRNLALCPANHAPLREHGALPRIVQLLIRAHEDTQRQQNGYVDGVRM EEIVEGTVGALHILAREAHNRTVIRGHKCIPLFVQLLYSPIENIQRVAAGVLCELAADKE GAEIIEQEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRGD NMSADLQWMIIRNNSSFLLKGNTFSKEPNNLRNRNSFRYNGLVQKKTVGVEPCADGKGVV LVTKTGWRKPAKSHVGVELKRGSRRSLNTIRKTLRNNRYRKDLKMAALRRASAILQSQKP VVVKQTRDEPYYCSQQIQIPPALPDILKQFTKAAIRTQPKDVLGWSAAYFRALANGETPP VKERLEMPVATQKTDTGLTPGLLRILNKQLGPRKTVDLNIIEEKWKDLALPKEQFDELVR IGGFGGTIEWLRYFALGCSALGENITDAMKTVCEILTADPDGGPSRIPFPLFKDLYTYLA KVDGEISQEHINEVTSHLQYYVDKQEGYVQPRNFTSPDCPKLSGKSDSASREQTITQVKT ELAIMQTQKLLQTMSDKCFKKCIPKPGSSLDNSEQKCVAMCMDRYLDALNVVSRAFSSRL QKEQA------------------------------------------------------- ------------------------------------------------------------ --FKKEYKNINIDQIEDLQDEMEDFTEQANEIQEVMGRSYGMPDIDDADLDAELDALGDE LGMDADTSYLDE-VNAPSVPTRVPGADSVTNKDGVPVDEFGLPQIPA-MTPMTPATPASP QLQNIVCTVNLNCKLDLKRIALHARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTG AKSEEQAKLAARKYARIVQKLGFPAKFLDFKVQNMVGSCDVKFPIRLEGLVLTHGQFSSY EPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKVREEIYEAFENIYPILKGFKKQSENGD DQFMEMNMEPESSSRDEVDDFQFEILTPDKIVSHMVDCIKEVNAVVEIPATTTRILLNHF RWDKEKLMERYYDGDQDKLFTEAHVISPHRSIVEVTCEICFLSLPKGLTGLECGHKFCTL CWTEYLTTKIMDEGMGQTISCAAHKCDILVDDATVMSLIRDPRVKLKYQHLITNSFVECN RLMRWCPAPDCGNAVKVAYSDAKPALCSCGHRFCFACGENWHEPVRCVWLKKWIRKCDDD SETSNWIAANTKECPKCRITIEKDGGCNHMICQNCKADFCWVCLGPWEPHGSSWYNCNRF DEDDAKKARDNQELSRSMLQRYLFYCNRYMNHMQSLKFEHKLYASIKVKMEEMQQHNMSW IEVQFLHKAVDVLCQCRQTLMFTYVFAFYLKKNNQSIIFEDNQKDLENSTETLSEFLERD ITSELLVDIKQKVQDKYRYCESRRKVLLDHVYEGYDKDWWEYIDMTSTDAKLSTTERVVR SVPFPPSHRLTMSEVFDAKGKPRPDVLKQHFILEGRVTEDVALRIINEGAAILRTEKTMI DIDAPVTVCGDIHGQFYDLMKLFEVGGPPATTRYLFLGDYVDRGYFSITERVYDACMDSF DCLPLAALMNQQFLCVHGGLSPEIHTLEDIKKLDRFKEPPAFGPMCDLLWSDPLEDFGNE KTTEHFTHNSVRGCSYFYSYQACCEFLQQNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSL ITIFSAPNYLDVYNNKAAILKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVT EMLVNILNICSDDELXE-------XTVAARKEVIRNKIRAIGKMARVFTVLREESENVLQ LKGLTPNGLLPLGALSGGKETLKSAMTGFSPSHKISGFDEAKVLDKMNERMPPRKGFSPR GGGRGGFRGGRGGGGRGGFGGGRGG--GGRGGMRGGRKVVVEPHRHNGVFVVRGKEDAIA TLNLVPGETVYGEKKIVVEEGKKIEYRAWNPFRSKLCAAIISGVDGIHMGPGKKVLYLGA ASGTTVSHVADIVGPEGCVYAVEFSHRSGRDLINVAKKRTNIIPIIEDARHPHKYRMLVG MVDCIFADVAQPDQARIVAINAHNFLKNEGHIVISIKANCIDSTAEAAVVFAGEVDKLRQ EKIKPMEQITLEPYERDHAIVVGQYRAPPKKMDPKKMADMAGRLKGAGRGLPTGLGLLAA AGGLAYGLYNSMYTVEGGHRAIMFNRIGGVQDYIMSEGLHFRVPWFQYPIIYDIRTKPRR VASPTGSKDLQMVNISLRVLTRPMQTMLPQVYRQLGQDYDERVLPSIVNEVLKSVVAKFN ASQLITQRSQVSLLIRQALVERAKDFHIILDDVSITELSFGKEYTNAVEAKQIAQQDAQR AQFFVERAKQERQQKIIQAEGEATSASLIGEAISNNPGYLKLRKLRAAQNISRTIAQSKN RVYLNAGSLMLNIVDEEFDKTLESYTGSSSDEEEINPRDKEQRTSKGETDFCVRIEQHGF GRREIEIAEQEMPGLMALRKRAQADHPLRGAKIVGCTHITAQTAVLIETLVALGAKVRWS ACNIYSTQNEVASALAEAGIPVFAWKGETEEDFWWCIDRCIICDSWQPNMILDDGGDATH LMIKKYPTMFNLIKGIVEESVTGVHRLYQLSKTNKLTVPAMNVNDSVTKTKFDNLYSCRE SILDALKRTTDVMFGGKQVLVCGYGEVGKGCCAALKGLGAIVSITEIDPICALQACMDGF RVVKLDEVIRHVDIVVTCTGNKNVITRTHLDKMKNACIVCNMGHSNTEIDVGALRTTDLT WEKVRSQVDHIIWPDGKRIILLAEGRLVNLSCSGIPSFVVSIAASTQALALIELFNAPTG RYKQDVYLLPKKMDEYVASLHLSSFDAHLTELTDEQAKYLGLSKAGPFKPNYYRYPDPDA IKMFVGQIPRSMDENDLRQMFEEYGSIYQLNVLRDKLSGQSKGCCFVTFYERKSALEAQN ALHNIKTLPGMQHPIQMKPADSEKKN-EERKLFIGMLSKKCTENDVRMMFAPFGSIEECT VLREQNSQSRGCAFVTYSSRQCAQNAIKAMHHSQTMEGCRAPLVVKFADTQKEKDFKKVQ Q------------------SVYVGQSLDTVKVKMQTFPKLYKNGLDCFLKTYRQEGYRGL YAGTIPALENSTLFMFYGLCQKGIMGAAIFCSFTLCPTELVKCRLQALTRQILRAEGVRG LYHGLTSTIAREVPGYFFFFGGYETCRYLLTPVGKTKEDIGARTILSGGIGGICFWLSIF PTDVVKSRHQVRETGFKSLYKGLGPTLIRTFPATGALFFAYELTKKSLH----------- ----------SNVSQLQQMINKIGTQQDSQDLRDKSHNMQHYTNQIAKETTKLLKDLAHI QSETKQRKMMKERLMNDFTAALNNFQAAQRQCAEKEKESVEDIDLDLIKEREESIKKLEG DIMDVNTIFKDLGQLVYEQGETIDSIESNVESIHVEEGNSQLSQAKTYQSKARRKKCICI IVVFVILAILGLIIGLSVGMVNLMKGVLVECDPAMKQFLLHLDETNALGRKFVIQDLDET HLFLSADSIDLLQEKIDDLMDKLNFPIGKSKEKAPTPQEGIQRLRETEEMLMKKSDFLEK KIETELTTAKKRVALQALKRKKRYEKQLQQIDGTLSTIEFQREALENASTNTEVLKVMGV AANAMKAAHKELDVDKVHDLMDDVAEQHELADEISSAISTQVGFGDPVDDDDLMAELEEL EQEQLDQDLLNVANLPSVPTAEDDEMKELAAWATSMNKFHNRVRQILMASGSTTFTKIVN KWNTALIGLMTYFREAVVNTQELLDLLVKCENKIQTRIKIGLNSKMPSRFPPVVFYTPKE LGGLGMLSMGHVLIPQSDLRWSKQTDVGITHFRSGMSHDEDQLIPNLYRYIMPWESEFID SQRVWAEYALRTDMIQALGGVEGILEHTLFKGTYFPTWEGLFWEKASGFEESMKYKKLTN ASKDVMDNTTTQKYWLDVQLRWGDYDSHDVERYARAKFLDYTTDNMSIYPSPTGTLVALD LAYNLHSAFGNWFPGAKPLIQQAMGKIMKANPALYVLRERIRKGLQLYSSEPTEPYLSSQ NYGEIFSNQIIWFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSV WAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKG SELQLPFQACLKVEKFGDLILKATEPQMVLFNLYDDWLKTISSYTAFSRLILIQRALHVN NDRTKVVLKPDKTTITEPHHIWPTLTDEEWIKVEVQLKDLILADYGKKNNVNVASLTQSE IRDIILGMEISAPSAQRQQIAEIEKQTKEQSQLTATTTRTINKH---------------- ------------XXXNLHLRTNHIYVSSDDIKETGYTYILPKNVLKKFIIISDLRAQISG YLYGVSPPDNPQVKEIRCIVMPPQWGTHQTVHLPNILPNHEYLKEMEPLGWIHTQPNELP QLSPQDITTHAKVMSDNPAWDGEKTVVITCSFTPGSCSLTAYKLTPSGFEWGRQNTDKGN NPKGYLPSHYERVQMLLSDRFLGFFMTPSSGSWNYNFMGVRHDANMKYELQLSNPKEFYH EIHRPSHFLNFSNIEESADREDMY-SYNATRNNLSINKNTKVICQGFTGKQGTFHSQQAI EYGTNMVGGVSPGKGGQSHLGLPVFNTVVEAKEATGANATVIYVPPPFCAKAIEEAIDSG ISLAVVITEGIPQQDMVRVKQKLLAQDKTRVIGPNCPGIIKPGECKIGIMPGHIHRPGRI GIVSRSGTLTYEAVHQTTQVGLGQSLCVGIGGDPFNGTNFIDCLEVFLNDPETDGVVLIG EIGGQAEENAAEFIKQHNGFQPKPVVSF-------------------------------- ----------------------------PNVELLKCTICHERLEDTHFVQCPSVAPHKFC FPCSRDSIKQQGAGSEVYCPSGKKCPLVGSNVPWAFMSGEIVTILGFSRYVEIGRVAYIA YGPDKGKLVAIVDVIDQNRALVDGPCSGVGRKQMNFKMLHLTKLKIISYGARVGTVTKAW NKAEITKKWEESTWAKKIANREKRAAMTDFDRFKLMKAKQTRNRLVNIEFGKLRAKAKKA CPLLLRVFCNMGRHNMIGEYGRGNTPSNELQIYTWMDASLKELTSLVKEVNHDAQMKGTF FDFALVYPESIRGLYRMRDIGTTCAGKRGADDNTTLAKCNFQIGDYVDISITPPQ----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------KDIDVVNGAGKCDKMRLLNILMQ LRKCCNHPYLFDGAEPGPPYTTDKHLVDNCGKMVILDKLLPKLQEQGSRVLIFSQMTRVL DILEDYCGWKNYEYCRLDGQTAHEERTQSIEAFNMPNSKKFVFMLSTRAGGLGINLATAD IVI--------------------------------------------------------- ----------------------------------DVDIDILLERGEKKTEEIAKKMEKLG EGNLRNFEMDVQEKSVYQFEGEDYRDKQK-GGIGMWIEPPKRERKANYAVDAYFREALRV SEPKAPKAPRPPKQPNVQDFQFYP------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------EEEDRFLVCMLHKLGFDKENVYDELRMAVRQAPQFRFDWFIKSRTA MELQRRCNTLITLIERENMELEERERAEK--STGPSWADQVDQVEDGELPPPSEDY--NK GLKVITEYKYNDEGKKVKVVKTYKVEKKRVPKSIARRKGWKKFGAAERDPPGPNPANTIE DVYMQFVHDKQQKEQDPLAKLKVSCRICKGDHWTTKCPYKDTLTPLQDALRTAGKYIPPS MRDGATRRGESMHNDESATIRVTNLSEDTREADLQELFRPFGSISRIYLAKDKITGQSKG FAFINFHRREDAARAIQGVSGFGYDHLILNVEWAKPSMSETYNFLFKFLVIGSAGTGKSC ILHQFIENKFKEDSNHTIGVEFGSKVVNVGGKSVKLQIWDTAGQERFRSVTRSYYRGAAG ALLVYDITSRETYNALTNWLTDARTLASPNIVIVLVGNKKDLEQEREVTFLEASRFAQEN ELLFLETSALTGENVEETFLKCARSILTKIESGELDPERMGSGIQYGDASLRRLSTKRPD C---IQPSSKEKLDTADWPLLLKNYDKLNVRTNHYTPIPNGCSPLKRPIGEYIKTGFINL DKPANPSSHEVVAWIKRILRVEKTGHSGTLDPKVTGCLIVCIERATRLVKSQQGAGKEYV CIFRLHSAVDNEKKVLQCMETLTGALFQRPPLISAVKRQLRVRTIYESKMLEYDKERQLG ILWVSCEAGTYIRTLCVHIGLLLGVGGQMQELRRVRSGIQSEKDAMYTMHDVLDAQWQLD HNKDEAYLRRVIKPLEALLVSHKRIIMKDSAVNAVCYGAKVMLPGVLRYDDGIEVNDEIV IVTTKGEAIALAIAQMTTAVIATCDHGLVAKLKRVIMERDTYPRKWGLGPKATMKKGLMK QGLLDKYGRPNDKTPKDWSTSYTDYNLKRKIDSLDPDTEKRKKKKKKD------------ ----LKSGSAIAAAQRQGLEVETSKKFAGGTNRKAVTTKDTAKLDRETEELHHDKLGLSV GKIIMQSRQAKEMTQKDLATKINEKPQVVNDYEAGRAIPNQQVLGKLENALGVKLRGKDI GQPRGPRMLKPKALTQVLSQANTGGVQSTLLLNSEGALLAFSGYGDQDARVTAAIASNIW ASYLKTGKVT-------------------------------------------------- ------------AGATARISSKPQTLEDAYSPPANFLEIDVTNAEGKKRYTDYEVRMRTN LPIFRVKESSVRRRYSEFEWLRTELERDSKIVVPPLPGKAYSKQLPFRNDDGIFEDDFVE ERRKGLEQFINKIAGHPLAQNEKCLHIFLQEPIIDRNYVPGKIR--RVYSTRLAEVGVLE TPKLQGKYDTGQLFLHRVFGYRGVVLFPWLARVYDRDLATVGSKEVEARTHTYYQVLIDS RDCPHIRTQSEAVTFLGNQDNGSLYAIPGLDYVGHEDVLPYTTTEKQPIKHELFDKFLIH DPPFMPRDTLRAWQEKNHPWLELSDVHRETTENIRVTVMPFYMGQTQQTLVYWWRYCIRL EN------------------XXXXDSVRGRGVVNQEPVLSKNFPAFQYSSHVSLQAPSGH MWGTFKLEKPGGSMFEVKIPAFSLESKQDDSMATSKSANTYNRQNWEEADFPILCQTCLG DNPYIRMTKEKHGKECKICARPFTIFRWCPGARMRFKKTEVCQTCSKVKNICQTCLLDLE YGLPVQVRDAALKIADEMPKSDVNKEYYTQNMEREIAQTDGTVAPGELGKAKATSDMLLK LARTTPYYKRNRPHICSFWVKGECKRGEECPYRHDKPSDPDDPLSDQNIKDRFYGTNDPV ADKLLKRYTSMPQLDAPED-----------------------VLELKRIIEGITKVNPED QKLFKDNKSLGDVGFTSSTARAQAPATIGLAYREFEALEXXHTPT--------------- -----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMEDYVKIEKIG EGTYGVVYKGRNKKTNKTVALKKIRLESEEEGVPSTAIREISLLKELVHPNIVGLEDVLM QENKLYLVFEFLSMDLKKYFDSIPSGQVMDSKLVMSYTYQILQGIVFCHKRRVLHRDLKP QNLLIDNKGVIKLADFGLARAFGIPVRVYTHEVVTLWYRAPEVLLGSPRYSCPVDVWSIG CIFAEMVTKRPLFHGDSEIDQLFRIFRIMKTPTEETWPGVTSLPDYKPTFPNWKKNELQT AVNETGLDLLQKMLIYDPAKRISAKAALLHPYF--QIFTRLGQLGVGLAVVGGVVQSALY NVDGGHRAVIFDRFRGVQQNVIGEGTHFMIPWVQRPIIFDIRSRPRNVPVITGSKDLQNV NITLRILFRPLQDNLPNIYTNLGVDYDERVLPSITNEVLKAVVAQFDAGELITQREVVSQ RVSEDLSERA-------------------XFTEAVELKQVAQQDAERARYTVEKAEQQKQ AAVTTAEGDSKAASLLAEAFAKAGEGLVELRKIEAAEDIAYQLSRSPNIVYLPPNQQTLL ALPMKVVNAKQSVKIPDGVKISVKARKVTVTGPRGTLRRDFRHLDVDMRMDGKSKIIVEK WFGIRKELAAVRTVCSHITNMIIGVTKGYRYKMRSVYAHFPINIAITENNTVVEVRNFLG EKFTRKVSMLPGVTFVPSGAQKDEFVLDGNDIEAVSNSAALIQQCTKVKNKDIRKFLDGV YVSQKTNIV----------------------------------------LGAGESGKSTI VKQMKIIHEKGYSQEECLQYRPVVYSNTVQSMIAIIRAMGQLKVDFGHSDRADDARQLFA LASQAEDGEMSKELADIMKRLWKDSGVQECFGRSREFQLNDSAEYYLNSLDRISTPGYIP TEQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFIVAMSE YDLTLAEDQEMNRMMESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSSLTICFPE YAGSQTYEEAAAYIQMQFNKRKDTKEIYTHFTCACDTNNVQFVFDAVTDVIIKNNLKDCG LFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXMSFGSDEVNFLVYRYLQESGFAHSAYTFGIESHISQSNINGSLVPPAAL LSIIQKGLQYTEAEISIGEDGAERVIESLSLIDAVMPDVVESRKQAAQKNTNGEETEENM EIDGALEIPSSKATVLRGHESEVFICAWNPANDLLASGSGDSTARIWNLNDNSNANQLVL RHCIQKGGTEVPSNKDVTSLDWNCDGTLLATGSYDGYARIWSTDGRLNSTLGQHKGPIFA LKWNKKGNYILSAGVDKTTIIWDANTGVCTQQFAFHSAPALDVDWQSNNSFASCSTDQCI HVCKLGVDRPIKSFQGHRNEVNAIKWDPQGTLLASCSDDMTLKVWSMKQDTCLHDLQAHN KEIYTIKWSPTGPGTNNPNSPLILASASFDSTVRLWDVDRGVCIHTLTQHQEPVYSVAFS PDGRFLASGSFDKCVHIWNVQSGALVHSYKGTGGIFEVCWNHRGDKVGASASDGSVFVLD LRKTNNDLATLFECPVCFDYALPPIMQCQSGHIVCSFCRPKL------XGPLGNIRNLAM EKVASTVMFPCKYSSTGCAQTLLHTEKGDHEETCEFRPYCCPCPGASCKWQGNLEQV--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ELVFRHYQLWRLVTNFLFFGAIGFNFLFNMIFTYRYCRMLEEGSFRG---DMFFMFLFGG ILMTITVNLVFLGQAFTIMLVYVWSRRNPYVRMNFFGLMNFQAPYLPW------------ ------------------------------------------------------------ --GMELLSDQGFRIDGRKPCELRRIQSKLGVFGKPDGSAYVEQGNTKVLAAVYGPHEPRG NIVKQDKVVINCQFSMATFSTGERKRRPRGDRKSMELSMHLQQTFEAAIMTELYPQSQID IYVEVLQSDGGNYCTSVNAATLALIDAGIPMKDYVCACSASYLDDTPMVDINYLEESSGT ELIV-------------------------------------------------------- ------------------------------------------DEQMWNTSSMYLKIIDKF NEWFVSAFVTASRMRFIMLHDIKNEDGIRNFFQEMYEYYIKHSMNPFYELNTQVNSVNFN KKAQNCGRKFL------------------------------------------------- ------------------------------------------------------------ -----------------------GVCTHLGCVPIANAGEYGGYYCPCHGSHYDASGRIRK GPAPLNLEVPEHSFPGNGVLVVGMSRQIGRSVDPKKVSGELFTLTYGALVSQLIKDYENE DDVNKQLDKMGYNIGVRLIEDFLARSNVGRCHDFRETADVISKVGFKMFLGITPVVTNWS PAGDEFSLLLENNPLTDFVELPDGHSNLSYSNIMCGVLRGALEMVQLDVDVRFEQDQLKG DNITEIRLKFIKRLEDAVPVGED------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------QVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNK------------ ---------------------XXXXVRFPSHFSGDLKDLLRNLLQVDLTKRYGNLKNGVN DIKNHKWFSTTDWIAIYQKKVEAPFIPKSRGPGDASNFDDYEEEPLRIS----------- -MLSDTLLIVFISICTALLGEGMTWLLVYRTEKYQKLKMEVEKQSKKLEKQKESGGNPND KVKKKKIERQEERLKANNRDLSLVKMKSMFAIGFAFTALLGMFNSIFDGRVVAKLPFVPI SWLQNISHRNLLGEDYTHCSFIFLYILCTMSIRQNIQKMLGFAPSRAASKQGGGLFGA-- ------------------------------------------------------------ -----SLCAAELVCKEWYRVISDGMLWKKLIERKVLTDSLWKGLSERRGWAKSLFRPQPG EKIPDHKYYRALYPQIISDIERIENNWRTGRHTLHRIHCRSETSKGVYCLQYDDNKIVSG LRDNTIKIWDSQTLECTQVLTGHTGSVLCLQYDDNIIISGSSDSTIRVWSVKTGEMLNTL IHHCEAVLHLRFSDGIMVTCSKDRSIAVWDMQSPLDINLRRVLVGHRAAVNVVDFDDKYI VSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYCEGIVVSGSSDNTIRLWDIECGACL RVLEGHEELVRCIRVDRKRIVSGAYDGKVKVWDLNAALDPRAPAGTLCIRTLVEHSGRVF RLQFDEFQIVSSSHDDTILIWDFLNMAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNS TFISTIGIDFKIRTIELEGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNDKS FENIKNWIRNIEEHASSDVEKMILGNKCDMNDRRQVSKDKGEQLAISFGVKFMETSAKAS INVEEAFLTLARDIKAKMDRKLNDGETSADRNVEIWKIKKLIKSLEAARGNGTSMISLII PPKDQIPRVAKMLADEYGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVIYCGT IVTDEGKEKKVNIDFEPFRPINTSLYLCDNKFHTEALTALLADDNKFGFIVMDGNGALFG TLSGNTRDVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAETSVTLFITNDKP NVCGLVLAGSADFKTELGQSDMFDPRLQAKILKIVDVSYGGENGFNQAIELAAESLANVK FIQEKKLIGKYFDEISQDTQKYCFGVEDTLKALEMGAVEILIVWENLDITRYRLKNHAGG EEKVLNLKPEQEKDKTQFVDKQTGVELELIESLPLLEWMANHYKQFGATLEIITDRSQEG SQFVRGFGGIGGILRYQVDFQSMEQ-NDWDDDWDPDEY---------------------- ---------KLYIMDARPNVNAVANMAKGGGYE-DSQYQNMELVFLDIHNIHVMRESLRK LKEICFPTIDDTHWLSHIESTHWLEHIKQILAGAVKIADKVESNKTSVLVHCSDGWDRTA QLTGLAMLMLDPYYRTIEGLEVLIEKEWTSYGHKFAQRIGHGEDKHSDADRSPVFLQFID CVWQMTKQFPTAFEFNEQLLITILDHLYSCLFGTFLCNTEQQRVKEDIKHKTVSLWSYVN SQLDEFKNPLYHHVLYPVASLRRIELWTGYYLRWNPRMKPQEPVQLRNRELTMLKEQLQR RVDELQRELDAKNPGFRPFVPHIPFDMAMCEQAFPRARPAVDDKFFTDALLKRNTDLSPT AAEQAAVLSLVTKINSTIDNLILTPGSFDAAVIEEVRQVGSFKKGTMTIGQNVADVVVIL KTLPTTEAVAALGNKVIEDLRTSDPAEILSMLTNDSGFEVSSSEATVKVLITTIPPNLKK LDPELHLEQKVMHGHLAAIRHARWFEENAFHSSIKVLIRLLRDLRNRFEGLEPLTAWILD LLAHYCIMNTPNRQPLPINAAYRRAIQLLASGFFLPGSIGITDPCEGGNVRVHTVMTLEQ QDLVCYTAQTLLRVLAHGGFKQILGIEGNASIATEMSVWEGVVVTPSDKAYEK------- ------------------------------------------------------------ -------------------------------------------------------REAYP EGQTKERRRAAIAQALSGEVNVVPPSRLLALLGQALKWQQHQGLLPPGTTIDVFRGKAAV KEQEDERYPTQLSKSIKFGQKSHVECTRFSPDGQYLVTGSVDGFLEVWNFTTGKIRKDLK YQAQDNFMMMDDAVLSMNFSRDSEMLASGGQDGKIKVWKISTGQCLRRFERAHGKGVTCV CFSKDSSQLLSASFDQTIRVHGLKSGKALKEFRGHSSFVNDAVFAPDGHHILSTSSDGTI KVWNLKSTECQNTFKSLGGVAGSDITVHSVHPLPRNVEQFVVCNRSNTVVIMNMQGQIVR SFSSGKREGGDFVCCTVSPRGEWIYCVGEDMVLYCFSISSGKLERTLTVHEKDVIGIVHH PHQNLIGTYSEDGLLKLWKPMAAAAQTVTKVASFAAPRAKTFMKYARVELRPPAEMGEAS QSFQKLIKAQTGKWQTVTTQEASLITLEIACWFFVGEIIGRRSLVGYNIPGAVFYD---- ------------------------------------------------------------ -----------------------------LLQTDPYGRISIMQFFNYVMRKVWLHQTRIG LSLYDVAGQGFLKESDLENYILELIPTLPQLDGLEKSFYSFYVCTAVRKFFFFLDPLRTG KVKIQDILACSFLDDLLELRDEDLPKDVQESNWFSAPSALRVYGQYLNLDKDHNGMLSKE ELARYGTGTLTDVFLDRVFQECLTYDGEMDYKTYLDFVLALENRKEPQSLQYLFRLLDVQ NRGYLNVFALNFFFRAIQEQMKVHGQEPVSFEDVKDEIFDMVKPADPLKITLQDLIISGQ GDTVVSILIDLNGFWTYENRE--------------------------------------- -----KISPFEHQTYCQRTLREIKILTRFKHENIIHIQDILGAPTVHDLKDVYIVQCLME TDMYKLLKTQKLSNDHVCYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFG LARVADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYSKSIDVWSVGCILAEMLSNRPLFP GKHYLDQLNHILGSLGSPSAEDLKCIINDKARGYLQSLPFKPKVPWKTHADPKALDLLDK MLTFDPHKRITVEQALEHPYLEQYFDPQDEPVAEQPFTFETELDDLPKERLKELIYEETV RIKQM------------------------------------------------------- ---------------------------------QFALCIRGGEKLNIRAEELVVGDIVEV KFGDRVPADIRVISAHGFKVDNSSLTGESEPQSRSADFTNENPLETRNLAFFSTNAVEGT CKGIVVQCGDNSVMGRIANLASGLEVGDTPIAIEIGHFIHLITGVAVFLGVSFFIVAFIL GYFWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTI CSDKTGTLTQNRMTVAHMWFDNRIVEADTTDDQSSATYDKNNPTWINLARIAMLCNRAEF KVNQDDVPILKRECNGDASESALLKCVELSIGRVTEYRAKNNKVCEIPFNSSNKYQVSIH PNDKRYVLVMKGAPERILDRCSTILIEGKDIPMTDEWRDNFNQAYLELGGLGERVLGFCD YELPVDQFPSGYPFDADEENFPLTGLRFVGLMSLIDPPRAAVPDAVAKCRSAGIKVIMVT GDHPITAKAIAKGVGIISEGQECVEDIAARLNIPVSEVNPRDAHAIVVHGGDLRDMTPAQ IDDVLRNHTEIVFARTSPQQKLIIVEGCQRMGAIVAVTGDGVNDSPALKKADIGVAMGIA GSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLLFIVAD VPLPLGTITILCIDLGTDLVPAISLAYEEAESDIMKRQPRDPVNDKLVNQRLISMAYGQI GMIQASAGFFVYFVIMAENGFWPVRLLGIRKEWDSKGINDLEDSYGQEWTYAQRKILEYT CHTAYFTSIVIVQWADLVICKTRRNSVLHQGMRNNQLTFGLFFETGLAAFLSYCPGLDKG LRMYPLRFEWWIPPIPFSIAIFIYDEVRKSILRKHPGGWVEKETYYTFRNLSKAKKIALG AAAGGTGMAIALNELVLHPPKLPWSHSGPLDSFDHGSIRRGYEVYKQVCSACHSLNYINY RNLVGISHTEDEAKAEAQEALVTDGPNEAGEMFQRPGKLSDPMPNPYPNEEA-------- -------XXXXRHGKEDYVYHLLTCYCDVPAGVNLGEGQYFNPYFPGGAISMAKALYNEI IEYEDGTPATTPQLAKDVCTFLKWCAEPEHDRRKKLGIKCIMLFLSVAIYYMKRHKFTVI KSRKIEWVRPDLPSKCTYKVGMPEDSPHTRRERKPAIMPNILSNIGNTPLVRLSNLSKSY GIKCELLAKCEFFNAGGSVKDRIGLRMIEDAEESGTLKKGDVLIEPTSGNTGIGLALAAA VKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTSASFDSPESHIGVAHRLLQEIPNSHI LDQYRNASNPLAHYDGTAEEILEACDNKVDLVVVGAGTGGTITGIARKFKEKCPSCRVIG VDPEGSIIARPEDVTFYEVEGVGYDFIPTVCDLEHVDQWYKSNDQESLLMSRKMIKEEGL LCGGSSGANMSCAIRAIKEAGLKEGQRCVVIMPDSVRNYMTKFLSEDWMRERGF------ -------LGEYEGERNERDERHGHGKATLPNGDTYEGTYENGKRHGQGTYRFKNGARYIG EYCKNKKHGQGTFIYPDGSKYDGSWVDDQRSGYGKYYYVNADCYEGEWLNHVRHGQGVYT YQDTGSKYTGTWKEGKREGSGELIHANHKYVGHFKEDRTEGKGKYVFDIGCQQHGDYIMP AIMRLVSKDLSEPYSIYTYRYFIHNWPQLCFLAMDEEKCIGTIVCKLDFHKKIVRRGYIA MLAVDKDYRRRKIGSILVTKSIQAMVSNDCDEVVLETEITNKSALRLYENLGFVRDKRLF RYYLNGVDALRLKLWLK---------------------------------TEAPGQNTNL LVTDSKGHTLYHKDSAEKGKFAFTTEEYDMFEICFETKLPQGMQGAAREVFLNVKHGIEA KSYEDIAKAEKLKP------------XXIVNDFAYMRAREEEMRDTNESTHSRVLYFSVF SMLCLLGLATWQVLYLRRFFKSKKLIEEMESGRTSSVGNDILGFTGNVVNKADHGNLDWT RICEEAAKVITFIDLAGHERYLKTTVFGMTGHAPDFTMLMVGANAGVIGMCKEHLGLALA LSVPVFVVVTKIDMCPENVLSDTLKMLQRLLKSPGCRKIPVLVQNRDDVICTATNFSSER VCPIFQVSNVSGLNLDLLKLFLNLLSTRMLTEPAEFQIDDTFSVPGVGTVVSGTTLKGVI GINDTLLLGPDALGAFLPITVKSIHRKRMPVKEVRGGQTASFALKKSQIRKGMMMLSPKL EPKASWEFDAEVLVLHHPTTISVRYQAMVHVGSVRQTATIMHMDSGHLRTGDKANVRFRF IKNPEYLKPDQKLVFREGRTKAVGTITKPHPYVSANTRQHR-------QEKLGQTDDHHF YLFKVLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASGEELHTLEGHRNVVYAIAF NNPYGDKVATGSFDKTCKLWSSETGKCYHTYRGHTAEIVCLAFNPQSIVATGSMDTTAKL WDVICTLSGHSAEIISLAFNTNGTQIITGSFDHTVSVWDKRIHTLIGHRAEISSAQFNWD CSLIATGSMDKTCKIWDTSTGRNVGTLRGHDDEVLDVAFDYTGQYLLTASADRCYNATTH SKLEGHEGEISKITFNPQGTKILTASSDKTARIWDPETGECRQILEGHTDEIFSCAFNYE GNTIITGSKDNTCRIWR------------------------------------------- ------------------------------------------------------------ ---------------------------------------VSSTLPTGQLSNVPWRRTGVK YTNNEAYFDLIEEIDVILDKSGSTVTAEIQGYVDCLIKLSGMPDLTLSFVNPRLLDDVSF HPCVRFKRWESEKVLSFVPPDGAFKVMSYHIGAQNMVAIPVYLKHSIQYREGSGGRLDIT VGPRQTMGKTVENVSLVIPFPKAVLNVTLTPNQGKYSFDPVSKIMTWDVGQIDTNKLPNI RGNINLQTGQPVPESNPTISVNFTISQLAVSGVKVNRLDMYGEKYKPFKGVKYLTKAGKF QVRT-------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------CLLQEARQQILADLQ DKNIALGIDVDQYNLTEESPGISYKPNPTRVPKGSTTPQQWEDFSRYNKERADAEMKAS- ------XHTLHQTDNDQEAQKQATEYDLRKRIHEFERAKDELEWQKKNTEEEIAEM---- --------------------------------------------------------EKLK QAQHALDGLEQNLHRINEDLGLKINSLMLDKRCMDTRQKLERNLTLTGLTDLKENLARLI PEKQALIKEFRGKHGNTKVGEITVDMIYGGMRSMKSMVTETSVLDPEEGIRFRGYSIPEC QQLLPKAPGGDEPLPESLFWLLCTGEIPTEDQVKAISKEWANRADLPQHVVAMLNNFPNN VHPMAQFSAAITAMNSESKFAKGYASGMKKADYWEKVYEDSMDLIAKLPTVAATIYCNLY KDG-KIGAIDQDTDWSANFVNMLGYDNPQFTELMRLYLTIHSDHEGGNVSAHTCHLVGSA LSDPYLSFAAAMNGLAGPLHGLANQEVLVWLTRLMVTTEQMKEYVWNTLKNGQVVPGYGH AVLRKTDPRYTCQREFALKHLPDDPMFKLVSQLYEVVPDILLELGKAKNPWPNVDAHSGV LLQYYGMTEMSYYTVLFGVSRALGCLSSLIWSRALGFPLERPKSMSTEGLIKLV------ -----------------------------------------LHNYCQSDGVLFCKSDFHK NVTARNLQ-DSLFVHRDTSYNNPDTKFDFTEENLKRAESILANYPEGHKQAAVIPLLDLA QRQHGWLPLSAMNKVASYLSMPKMRVYEVATFYTMFNREPVGKYFIQICTTTPCMLGGVG SDVIVDAIKKKLNIKLGETSKDNMWT---------------------------------- ------------------------------------------------MQKYEKLEKIGE GTYGTVFKAKNRESHEIVALKRVRLDDDDEGVPSSALREIALLKELKHKNIVRLHDVLHS DKKLTLVFEYCDQDLKKYFDSCNGEIDQDTVKSFMFQLLKGLGFCHSHNVLHRDLKPQNL LINKNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIF AELANAGRPLFPGNDVDDQLKRIFKLLGTPTDETWPGMTQLPEYKKYPMYHVTQQVVPKL NAKGKDLLQKLLVCNPSHRLSADDGMEHSYFADLNSTI-XXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXWYCDDRMAEWERQRDNLCGTKSAHDSLMYGSTEIWSSWY FSPTQPGGFYGIQPHGFSNVLIPDKETLIRDAGKLEVLDSLLARLKAEGHRVLIYSQMTR MIDLLEEYMWHRKHKYMRLDGSSKISDRRDMVEDFQTKSDIFVFLLSTRAGGLGINLTAA DTVIFYDSDWNPTVDQQAMDRAHRLGQTKQVTVYRLITKGSIEMRILERAKEKSEIQRMV ISGENFKPDVLKAKEVVSLLLEEEELTTKMSLETIPKDLRNLRACLLCSLVKTFEQFEFD GCDNCEEYLHLKHNRDGVYECTSSNFDG-------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --IIPGIKVDKGVVPLAGTDGESTTQGLDGLAERCAQYKKDGCDFAKWRCVLKISSHTPS YQSMMENANVLARYASICQQNGLVPIVEPEVLPDGDHDLLTAQKVTEQVLAFTYKALADH HVYLEGTLLKPNMVTAGQACAKRYTPQENSQATVTALQRTVPAAVPGITFLSGGQSEEDA SVNLNEINKKPWALTFSFGRALQASVLRAWGGKAENVKAAQDELAKRAK----------- ------------------------------------------------------------ ------------------------------------------------------------ -------QEHDEPVLNHLQDIKVKFTMGFTLDFHFDSNEYFTNTVLTKQYIMRSEPDEAD PFSFEGPEIIKCKGCSIDWKKGKNVTVK-------------------------LFNFFAP PEAPEGEVDEDTEALLAADFEIGHFIRERIVPRAVLYFTGEALDEEEEEDDNDD-IILLK EGTDSSQGKPQLISNINACQAIVDAVRTTLGPRGMDKLIVDAGGKATISNDGATIMKLLD IVHPAAKTLVDIAKSQDAEVGDGTTSVVLLAGEFLKLCKPFIEEGVHPQIIVRAFRKATY LTVQKINEISVK--------XELLMKCASTALSSKLVSQQKDFFSKMVVDAVMILDELLP LNMIGMKKVTGGALEDSQLIAGVAFKKTFSYAGFEMQPKSYKN----------------- -----------XXSIVDAEWSILYDKLEKIHKSGAKCVLSKLPIGDVATQYFADRDMFCA GRVSDDDLKRTMKACGGAIQSSVSSMTLGTCENFNERQIGGERYNIFT------------ ------------------------------------------SKYLRDYSRTIPGKEQLL IGAMAKALEVIPRQLCDNAGFDATNILNKLRQKHAGRWFGVDITTEDIADNFETFVWEPA VVKINAITAASEATCLILSVD--------------------------------------- -------------------RIKKAREIMPRPVGGALRPVVRCPTFKYNTRTRTGKGFTLE ELKAAGISK------------------------XVQRLKEYRSKLILFPKKMSNPKKGDA SAEEMKMATQLSGEVMPITQVSKKEKARKITDEEKKFNAFAAIRQARANKKLFGIRKKRA QE-MTNIKVFSGSSHPDIAQKIADRLGIEPGKVILKKFSNGETCVEIGESVRGEDVYIVQ SGCGEINDMLMEMLIMLNACKIASSCRVTAVIPCFPYARQDKKDKSPISAKLVANMLSVA GADHIITMDLHASQIQGFFDIPVDNLFAEPAVLKWIRENINEWRNSIIVSPDAGGAKRVT SIADRLNVEFALIHKERKKANEVASMVLVGDVKDRIAILVDDMADTCGTVCHAAEKLLEA GAVKVYAICTHGILSGPAVSRI-------------------------------------- -------------------LFCRYFEHRLPEIEDVVMVNVRSIAEMGAYVHLLEYNNIEG MILLSELSRRRIRSINKLIRVGRNECVVVIRVDKDKGYIDLSKRRVSPEEVMKCEEKFAK AKAVNSILRHVGELLNYTSDSQLEALYKKTAWHFDAKYGKPGAAYEAFKHAVANPEVLDE LDLDDETRKVLVDNIKRRLTPQAVKIRCDMKVACYGYEGVDAVKASLRKGLEMTTEEMPI KINLIAX---------------MARGQQKIQSQQKAQEAAAKRKPDQRKAAQKALTISCK VCKSQMPDLKTYKQHFENKHPKAELPQDLKEVMLGNLQSDMNKHGVATIPKGHCAACSKP IVGQVITALGRIWHPEHFTCVQCHEELGTQNFFERDSLPYCEKDYHQLFSPRCAYCGGPI LDKCVTALDKTWHPEHFFCAQCGRPFNDEGFHEKEGKAFCREDYFEMFAPKCGGCNRPIM DNYISALNRQWHPECFVCQECRIPFG---------------------------------- -----MYRKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCHPCFVKLFMRPLTDEETKAFFE KLSKYIGESIKQLIDRPDGAYCFRLHNDRVFYVREDLMKKAAHASRENLVSFGTCFGKFT KSGKFRLHVTALDFLAPYAKFKIWVKPSAEQQFLYGHHIMKNGLGRITENTQQYQGIIVC AMNDTPLGFGVAAKSTQECRHTDPMTIVAFHQADVGEYIRSEEHLXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --QAETAANRICKVLKVNQENERLMEEYERMASDLLEWIKRTTPWLENRTTDNTLPGTQS KLEEFREYRRKHKPPKLEEKAKLETVFNTLQTRLRLSNRPAYLPTEGKMVSDIAKAWKGL EFAEKGFEDWLLSELQRLERLDHLAQKFKHKCDIHEEWAHGKEDMLQSTDYKKCRLNELK AFKKKHEAFESDLAAHQDRVEQIAAIAQELNALEYHDAPAVNARCQRICDQWDVLGTLTQ KRRVALDEAERIMERIDQLHLEFAKRAAPFNNWMDGAKEDLVDMFIVHTTEEIQGLIDAH EQFKQTLGEADKEFNAIIGLVNEVQKIGMQ--------XXXXXXXXXDIANKWTEVRQLV PKRDGVLQQEMIRQQNNERLRLQFAKKANTVGQWIERHLDHLVSISLQSGSLENTLTQFK SFDTEVHQYKPNIDELERYNQEVQ-------------------------------INETE NQILTRDSKGITEDQMDEFKKSFNFFDKKKSRRLDPNEFKQCLVSLGFNIGHDRQGDAEL QKMMAIVDPNGTGFVTFEAFLDFMTRETTDTDTAEQVMQSFKILSGDQPYITAEILRREL PPDQAEYCIARMAPYKGPDAVPGALDYSSFSTALYGESDLNKLPIDALDLKDKRVLIRVD FNVPLKGKDITNNQRIVAALPTIKYALDQKAKSVVLMSHLGRPDGRRQDKFSLAPVAAEL KKLLGKDVLFLNDCVGAEVEKACKNPAAGSIILLENLRFHTEEEGKGVDEAGNKVKAKDE DVEKFRESLTKLGDVYVNDAFGTAHRAHSSMVGVKLSQRASGFLLKKELTYFAKALDNPV TPFLAILGGAKVKDKIQLIENLLDKVNEMI------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MAGIPPKSWQPAYVTLNTTMGEIVVELY WKHAPKTCTNFAELARRGYYNGVKFHRIIPDFMIQGGDPTGTGRGGASIYGKEFD----- ----XXAGILSMANSGPNSNGSQFFISLAPTQWLDGKHAIFGRVFSGMQVVKRMGMVDTD NNDKPYEDVKI------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------KELLISFGPLKAFNLVKDSATGLSKGYAFCEYVDQACAGLMGMQLG DKKLIVQRASMGAKNAQQAPVQIQVPGLNLAQ-PTEVLCLMNMITPEELEDEEEYDDIVE DIREECGKYGAVKSLEIPRPIQGVEVPGCGKIYVEFNSIIDCQKALQGLTGRKFASRVVV TSFYDPDRYHRREFFLPLFDRILVERVAANTKTASGLMIPEKAQEKILRATVVAVGPGAR LEDGSHVPCSVKTGDQILLPEYGGTKIKLDDQEYTLFRDGDIMGKFEXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMADEALAKAGLHFDELNK IRVLEPEVQQQTTELKEECKDFVDKMSEFQSIVGTFIGMVDTVASEVEKEKMKAIGSRNL LKSITKQREAQQQQLQALITEKKMQLERLRVQYEHLQKEESEQNDFIEQFILQK------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------KALEQLNGF ELAGRPMKVGHVTERTPDSNALDTDELDRAGIDLGATGRLQLMAKLAEGTGFQLPQAAAN ALNMPQQAAAPPIATQCFMLSNMFDPITSSPTWEQEIRDDVIEECNKHGGVLHIYVDRAS PQGNVYVKCPSIAAAVASVTALHGRFFAGRIITAAYVPLPNYHQLFPMALNAVQLVMPS- ---EDEMSP-PPQMPKKRPRRGAVSAEVYSEEDAASYVKKVVPKDYKTMAALSKAISKNV LFTHLDDNERSDIFDAMFPVHRHGGEIIIQQGDEGDNFYVLDQGEVEIFVNNTLVVTLGD GASFGELALIYGTPRAATVKAKTDVKLWGIDRESYRRILMGSTIRKRKMYEEFLGKVSIL ENIDAWERSTIADALEPVQFEDGQEIVRQGDPGEDFFIILEGTASVLQKRAEGDDAVEVG KLGPSDYFGEIALLLDRPRAATVVPRGPLKCVKLDRGRFERVLGPCSDILKRNISQYNSF VSLSV------------------------------------------------------- ------------------------------------------------------------ CTSAKHVVNMCLNVIKVSVFLQNWSHVLSYVNKAEATPETP-GKEGSQATMTKLKCAAGL AELATKKYKSAAKYFLQANFDHCDFPELLSANNVTIYGTLCALASFDRQELQKHVLSSSS FKLFLELEPPLRDIIHKFYDSKYASCLKLLEEIKDNLLLDMYLSAHVNTLYVQIRNRALC QYFSPYMSADMNKMASAFNTTVAALEDELMQLILDGQINARIDSHNKILYAKDIDQRSTT FEKSLNIGKEYQRRTKALILRSAMLKNQIHVKMPQRDGSQGGEMSIAPGTASSMPSQTEL LSKAEDLADQVLRHSKHVLPHIARLCLISTFLEDGIRMWTQWGEQRDYMDSQWGCG---- ---XLVNLVGQLAGCIMVLSRQKVPIACGILFSIIFIQTIAYSILWD------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------RHTVTFMPGDGVGPELMGHIKEVFRFAGAPVDFEEID FSRNGIAIKGNRETNFKSRNVQLRTELDLFANVLWCKSIDGVKTRHDNIDIIIIRENTEG EYKNLEHENVSGVVESLKIITADASRRIAKYAFDFATKHGRKKVTAIHKANIMKLGDGLF LKCCKEVSELYPDIQYDSMIVDNCSMQLVSKPQQFDVMVMPNLYGNIISNIGAGLVGGPG VVPGMNVGTDYAVFESGCRNTGKHIAGKNIANPTGMLLAGVDLLVYLGLEQHAGLIQDSV INTISQKEYQTPDLGGQATSTEVVQAIIDDITDDFQKFMMRSSAIMERALAEETDIFTDY SGLNADDDISASDKLKLNRTFFDERWSKHRTVTCMDWSVQHPELLVASYNNNEESPHEPD GVALVWNLKFKKTTPEYVFHCQSAVMSTCFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPV QRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSQPQDSMELQHKQSK VAVTSFSFLSGDVNNFVVGSEEGAVYTAVRHGSKAGISEMFEGHQGPVTGIDCNVVPGVV DFSQYFITSSIDWTVKLWNIKENKPLYSFEDNSDYVYDTCWSPIHPALFASVDGVGRLDL WNLNHDTEVPTATTYNVALNRCRWHQSGHQIAAGDDIGKIHVYDVGEHIAQPKNDEWKRF VHTLQEIRNNKADAEEEQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------ ------------------------------------------------------------ --NAWAETVSHVYKMPTGMSFQDGAALPMNYLTAYIILFELGGLRKGQSLLVHSVGGGVG HAVCQLAKTVEDVQVFGTASYKHDAIKNN-VSYLYDH-VVDYVQEVKKVSPEGVDLVLDC LCGDDVNKGITLVKPMGRYILYGTSNIVTGETRSFFSLAKSWWQVDKISPMKLFEENKTI TGFHLRTLLLMDTLFKLYNTGKIRPQIDSAYAFEDIGEAMQKMHDRKNIGKIILDPGLMS RK-TPSDFLKQIIGRPVVVKLNSGVDYRGVLACLDGYMNIALEQTEEYVNGQLKNKYGDA FIRGNNVLYISTQKRR---ADQGALLLKRQLIDLQKKPVEGFSAGLIDDDDIYRWEVLIM GPQDTPYEDGFFKAHLTFPKEYPQKPPLLKFVSEIWHPNIDENGEVCISILHEPGEDKYG YERPEERWLPIHTVETIMVSVISMIADPNVESPANVDAAKDFRDDKPQFTKRVTRCVKKS QE-TVRPENPLMQQTLFDFGEYVAECLPKFVQSVEVTKGDELQVMISPEGVVPVISFLKD HHNGQFLNIVDIAGVDVPTRPYRFEIVYLLLSLRYNARITVKTYTDELTPLESICSIFHG ANWYEREIWDMYGVFFANHPDLRRILTDYGFEGHPFRKDFPLSGYVECRYDDEVKRVVLE PLELSQEFRKFESQTP----------LNPFCQVDYRAKLWTCNFCFQRNPFPPQYAAISE QHQPAELIPQFSTIEYTLTRATCNPPVFLFVVDTCMDDEDLQALKESLQMSLSLLPPNAL IGLITFGKMVQVHELGSEGISKSYVFRGTKDLDAKQIQEMLGIGRGVPQLPSNRFLQPVH KCDMALTDLLGELQRDPWPVAQGKRPLRSLGTALSIAVGLLECTYPNTGARIMMFTGGPC TQGPGMVVGDEKKFPIRSHHDIEKDSVKYMKKAMKHYEALANRCSNNGHIIDIYSCALDQ TGLHEMKFCCNHTGGHMIMGDSFNTSLFKQTFQRVFAKDVKGEFKMAFCGTLEVKTSREL KIQGAIGSCISTHVGPSVSETELGMGGTSSWKICGLYPNSTLGIYFEVVNQHNAPIPQGG RGYIQFITKFQHSSGQKRVRVTTVARNWVDASMNIQHIAAGFDQEASAVLMARLAVFRGE TDDGP------------LCQKFGEYNKDDPNSFRFSEQFSLYPQFMFHMRRSQFLQVFNN SPDETSYYRHALLREDLTQSLIMIQPILYAYSFNGPPEPVLLDSGSITADRILLMDTFFQ IVIFHGETIAQWRKAKYQEKPEYENFKQLLQAPVDDAQEILQTRFPMPRYIDTQAGGSQA RFLLSKVNPSQTHNNMYSDSGAPVLTDDVSLQVFMEHLKKLAVSTST-----SESQLKLV TDLEIEMMADMYNRMTRVCQEKCVPPKYKDADLAKGEAVCLDRCVAKYLEIHDRIGKKLT AMSQQDEEQLKK---TAAPTVIHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYR KKVTLDGEEVQIDILDDYAAIRDNYFRSGEGFLCVFSITEQESFQATAEFREQILRVKND ENIPFLLVGNKADLEEKRQVTLEEATTRAQQWNVPYVETSAKTRANVDK----------- ---------------KLYTGLREVVTEHAVVKVKTEVLESLHNNFLQTLNSSWNDHQTSM VMIRDILMYMDRVYVQQNNVDNVYNLGLMIFRDQVVRCPEIQDFLRETLLDMVAKERKGE VVDRGAVKNACQMLMVLGIDSRSVYEEDFEKPFLDQSSDFYRMESQKFLAENSASVYIKK VEARIKEEAERATHYLDKSTEDPIVKVLEEELISKHMKTIVEMENSGVVHMLKNNKTEDL GCMFKLFVRVPSGLKTMCDCISCYLREQGKALVAEESGSKNAITFVQSLLDLKDRFDHFL HESFNDDKQFKQMISGDFEYFINLNTKSPEYLSLFIDDK--------------------- --------------YYKQHLAKRLLLNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFKD MTVSNTTMEEFKTHVTSSTNLHGVDLFVRVLTTGFWPTQSAMPSCNVPAAATNAFDAFKR FYLGKHSGRQLTLQPNLGSADLNATFFGIKKEEGDGSKGPRKHIIQVSTYQMCVLMLFNK QDRFTYEEIKSETDIPEKDLMRAIQSLALGKITQRILSKEPKTKDICPDHIFSVNDMFTS KLYRVKIQTVAAKGESEPERKETRSKVDEDRKHEIEAAIVRIMKARKKLQHNVLVAECTE QLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKIYTYVADRIAIFPSRMALTTMKGKLK GAQKGHSLLKKKADALTLRFRQILKKIIETKMLMGDVMKEAAFSLAEAKFASGEINHMVL QNVSKAQTKVRFKKDNVAGVQLPIFEHYTDGTDTYELTGLSRGGQQLGKLKKNYSKAVEL LVDLASLQTSFITLDEVIKITNRRVNAIEHVIIPRIENTLAYISTELDEREREEFFRLKK VQNKKGKDR--------------PIKVCVTGAAGQIAYSLLYQVAKGQVFGDDQPIILTL LDIPPMMPVLQGVVMELDDCAFSLLREVIPTSDEAVAFKDIDAAMLVGAMPRREGMERKD LLAANVKIFKSQGKSLDANAKKTVKVVVVGNPANTNALICKKYAPSIPAENFSCLTRLDQ NRAKAQIAGRDSVKNVIIWGNHSSTQFPDVSHGTVVSEAVKDDNWIKNEFIKTVQQRGAA VIKARKLSSAMSAAKATGDHMRDWFKGTPQGEYTSMGIVSDGYGIEAGLVYSFPVTISGK YTIVQGLEVDTFAREKMDATANELKQEMTTALEVCSGNQGVLMVGPNFRVGKKIGCGNFG ELRLGKNLYNNEHVAIKLEPMKSRAPQLHLEYRFYKSLGQAEGIPQVYYFGPCGKYNALV LELLGPSLEDLFDLCDRKFSLKTVLMIAVQLITRMEYVHSKHLIYRDVKPENFLIGRQSN KKQHIINIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEAL GHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEELATYLRYVRRLD FFETPDYDYLRKLFLDLMETNHWDCDSEFDW------------VVSSTNGELGG-GGHSN TPITPQAEVEHVDETKCCMTTIRPFTCDDMFKFNSVNLDRLTETYGLPFYMQYLARWPEF FQVAESPTGQIMGYIMGKAEGTKENWHGHVTALTVAPEYRRLGLAARLMKNLEETSDKKK CYFVDLFVRVSNTVAIAMYERLGYTVYRRVIEYYSGEVDEDAFDMRKALSQDKEKKSVIP LKHPVRPDDL-------------------------------------------------- ------------------------------------------------------------ --------LWDLDHGFAGVILIKKAGDGSKTTKGCWDSIHVVEVQEKATGRNAHYKLTST AMLWLQTNKTGSGTMNLGGSLTRQTEQDAPVSDASPHIKNIGTMVEDMENKIRNTLNEIY FGKTRDIVNGLRSVQPLSQKMLQNELANALSRRGQFDEDLDDLEEPLDEVENQENIDVLP ADERVAPEKRMTTPYMTKYERARTLGTRALQI---------------------------- ------------------------------------------------------------ -XAFYGLGLSNQVGAIDRAVLWPQIVRDRIKTTYMYFGGGIAITAASRSPVILNLMMKNS IMAMIGTFAVIIGSGMVVRSIPYKEGAKQLAWMGHAGIMGAVIAPLCLLGGPILVRAAWM TAGIVGGLSTIAACAPSEKFLNMGGPLACGLGLVFASSIGSMFLPPTSALGAGLYSVAMY GGLVLFSLFLLYDTQKIIKRAETHPVYSTVPFDPINSSISIYLDTLNIFIRLAMIMAGGG GRRKMEIVYVYTKKRAEFGRQCNFSDRPAELHVDITPDPSLLENFIERNPVDSKIQCAQE MSEHEVNTERFETENRGINHTEGGWPKDVNAQEIEQVMRFRKKVEKDEMYINTIQQLGGV MEHCIRQNNAIDIYEEYFDDVEVDSTDEPPSAKTINVFRDPNEIKRTATHISWFPDGPRK LAIAYCNLEFQGSSADTMDSYIWDVENPNKPEMVLKPVSPLVCLEYNPKDAHVLLGGCYN GQIAFWDTRKGSQPVEMSPIEHSHRDPAYKAIWLQSKSGTDCFSASTDGQVLWWDIRKMG EPNEILVLDPTKKQDLTKACGAMSLEYEPTIPTKFMVGCEQGSIMSCNRKAKTPAEKIVA LYPGHHGPVYALQRNPFFPKNFLSVGDWTARIWSEDIRESSIMWTKYHMAYLTDGCWSPV RPAVFYTTKMDGTLDIWDFIFKQNDPTLSLQVCDEALHSIRVQDQGRLIATGSQSGTTTL LELSDGLCTLQRNEKALVTAMFERETRREKILESRHREMKLKERNKSSWEDKIKYLSPIS NPLASRKLTKKIYKIIKKAIRKGVREVQKFVRKNEKGLVILAGDTNPIEVICHMPVICEE QDLPYCYAPSKEDLGAACSSRRPTCMVMVKPHSDYQDLYDELETEMKGLPIPIMPVENLE EQGLEKNPNLQLPQWRFRLGTDRYKNDKTIQNNLMEAIKADNMTPFYEEVAAEFGWKVDT QLVAKMRAANEEHLKDLDSKIEDAEKNLGETEVRDFMLNKAEYYCKIGDKENCLSQFRKT GEKTVTLGYKLDMVFHQIRLGLFYMDHDLITRNLEKAQSLIDEGGDWDRRNRLKVYKGAY SMAIRDFKTAANLFLDTVATFTSYELMDYKDFVTYTVLCSVIALERPKLREKVIRGSEIL EVLHSLPEVKEYLFSMYECQYESFFKQLAQMEEKLKYDRYLSKHYRFYAREMRVLAYAQL LESYQSLTLVYMAKAFGVTVEFIDRELSRFISQGRLHCKIDKVGGIVETNRPDSKNHQYM ALIKQGDLLLNRLQKLSRVINISRLYRTGRATVKGIPYNKLTVGVPKEIFQNERRVALTP QAAAAMKKGWNVNVEEGAGAAAKFSSADYEAAGAKVTAEEAYQSDLVFKIRAPTLEEVNL LKPKSTLTSFIYPAQNQELLDALAKKQATVFGMECVPRISRAQVFDALSSMANISGYKSV ILAANNFGRFFTGQITAAGKVPPAKMLVIGGGVAGLACVGTARNMGAIVRAFDTRAAVKE QVESLGGEFLEVKIKESGEGGGGYAKEMSPEFIAAEMELFAQQCKDVDIVITTALIPGKP APKLISKQMIESMKPGSVVVDLAAEAGGNIETTKPGELYVYNDVTHIGYSDLPSRLPTQS SSLYANNISKLIMSFGFYLDMEDEVCRGSIILKEGEMMWPPPKPPPPNYFKEYLTDSGVY TAGLAGMVGLGIAAPNAAFATMLTTFGLSGIVGYHTVWGVTPALHSPLMSVTNAISGITA VGGLMLMGGGYAPSNTAEILATTAAFISSINICGGFVVTQRMLDMFKRPDDPPEYNKLYM LPGAVFLGGYGYAQQFDYPDLHQVAYLSAGLCCVGALSGLSSQKSARVGNALGMIGVGSG VAVTLGMLKPTPELLAQMGMAMGAGGLIGAVMAKRMEVTDLPQMVALFHSLVGAAAVITC VANFMVEYPHMADNPAAGMLKTVMFLGTYIGGVTFTGSLIAFGKLQGTLDSAPLLLPGRH ALNLGLLAGNVGAMGYFMTTQDNAGMAMLGTTTALSSVMGVTLTAAIGGADMPVV----- ---GWALCAEGFMLNNSLMTIVGALIGSSGAILSYIMCKAMNRSLPNVILGGFGTSSTGG GKAMEIVGEATRVDTTQVIDYIKDAKNIIITPGYGLCVAKAQYPIAEMVKILREKAKNVR FAVHPVAGRMPGQLNVLLAEAGVPYDIVLEMDEINDDFPTTDLVLVIGANDTVNSAAEDD PNSIIAGMPVLRVWNSEQVIVMKRSLGVGYAAVDNPIFFKENTGMYLGDAKKSCDALVAQ VKMARPEGLPGCPPGLEYLTQIDQILVHQQVELLEMMTGFETQNKYQVKNSMGQQVYFAQ EESDCCMRQCCGPQRGFTMHITDNLGQEVIRCHREFKCCAGCCWCAGCAMELIVEAPPGQ VVGSVKQAPCPPRFDIKDAIFDVEGPVCMCQGPCCAWDQDFVVKSQEVGKISKQWTGFVK EYFTNADNFGVSFPMDLDVKLKAVMVGAVFLIDFMYFEQNNNXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMD RSGGLVQRRNVSSEEDDHDSKETRLTLMEEVLLLGLKDREGYTSFWNDCISSGLRGCILI ELAIRGRCELEKTGMRRRSLLSRKVICKSDSPTGDVLIDEALKHIKETDPPESVQGWIEY LSGETWNPLKLRYQLRNVRERLAKNLAEKGVCTTEKQNFLLFDMTTHPLTDSTIKQKLVK RVQDSVLSRWTNSAQRMDKRTLSLIYLAHASDVLENAFAPLSDDDYEVAMKRVRELLDLE LDQEAMKDGANELMWAVIAAFIK------------------------------------- ---------------------------MSKPVSYYMPAEKICEKLNSKDSQICELKYDKT IDLSEVNFKKLKVKDLKKILSDWNDQCKGCTEKSDFISRIEELMPKF--------ILKGF QLNWMNLRDADSGKILWQGSEDLSNPQREHEARVPKKILKCRAVSREINFSSQEQMDKFR LEQKVLFKGKCLEEWFFEFGFVIPSSTNTWQSIIEAAQESQMMPPNVLNGNVLIETKFYD GDLLVSTSRVRIFYVMPKVISRSVVCTDTKDEEEYQGEKPLYVYYCLCGQMTLILDCPTE KLPLRRRDQSRVIDRHKHAHKITADDDEVIHLKR-------------------------- -----------------------------------KEMGKFSSVTISTVEAEEEELEAKE IADSYASNAAVIQKQMLRKGLGKRKALEQAE-EAKKMRTKGTLIDLVRQCTRMATQQQKR GYAEMAFTFASPNEVNVKQVDVPSFSGSFGILPEHVPTLAVLKPGVVTVTEEDGSVNRIF VSSGSVTINDDSSVQILAEEAAPISNLDVAAAREGLNKATQELQTEEAKAEAQIAVDTFE ALGKALECKYLATELMLRLDETGKNKEVIETGHGLEKKKRFKYNTAELRLIEALQ----- ----------EXXXSLRYSKGMSETMQTLHGLKNKGVKVELGIPEELWDTPSAEVTIMQR HCFTVAEELEETIEDWYFHHQEPLMKYLC----------IFTPTDVTSEADVKNAVIAKE KFGKLDVTVNCAGIGIAVKTYNFDKDKPHSLEHFAKVLTVNTVGTFNVIRLSAGEMGKNE PNPDGQRGVIINTASVAAYDGQMGQAAYSASKGAIVGMTLPIARDLAKQGIRVSTIAPGL FDTPLLASLPEKVRIFLASTIPFPQMLSTPDVYAHMVQSIVENPTLNGEVIRLDGALRQR DFHFKIQGRNTDAKSQISTDYPVVDHTYDAVVVGAGGAGLRAAFGLANEGFKTACITKLF PTRSHTVAAQGGINAALGNMEEDKWQYHFYDTVKGSDWLGDQDAIHYMTREAPQAVIELE NYGMPFSRLDNGKIYQRAFGGQSTKFGKGGQAHRCCAVADRTGHSLLHTLYGRSLYYDTD YFVEYFALDLIMEDGECRGVTAICLEDGSIHRFRSKNTVIATGGYGRTYFSCTSAHTCTG DGTAMVSRAGLPNEDMEFVQFHPTGIYGAGCLITEGSRGEGGYLLNSEGERYMERYAPNA KDLASRDVVSRASTIEIREGRGVGPDKDHVFLQLSHIPIDQLKSKLPGIMETAHIFAGVD ITRDPIPVLPTVHYNMGGVPTNYKGQVITYNGQDQLVPGLYACGEAACASVHGANRLGAN SLLDLVIFGRACANTITEENRPGDPIGEISQNAGEATVANLDGLRNANGDISTAELRLTM QKIMQSHAAVFRDGASLKEGCDKMSALYKDMNLKVTDKGLVWNSDLIE------------ ----------------------------DYSKPLEGQVKKDMKDHWRKHTMAWQDIESGN VCLDYRPVIDSTLDKSETDSVPPAVRSYMTALSQEEIISNTKTVVQGLDTLKNEHHQILN SLLSSMKTIKKGDTNLVEEKTGILKKSIETIELGLGEAQVMMALASHLQHVEAEKQKLRA QVRRLCQENAWLRDELANTQQKLQQSEQKSATLEEQKKHLEFMNEMKKYDSPEDLGFPED DDDNQSSAMAQAASGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHD HPDVATM-----SAYLKQGKYKQAEILYKEVLTAHEKEFGKAHP---------------- ------------------------------------------------------------ -----------------------------KIAGKYSQESEAEVIGWFQALIAPGMHNVQQ TLKNGQLLCKL----KAKKFKIKFNTMSAPFKQMENITVFLNACEAYGVPKNSLFQTVDL FEGRNMAQVMATILQLGTECQRTGFDGPTIGPRPTEKHIVEFSEEQLKAGQLQAGTNKCA SQAMGAVRHIADIKADDMSKDSQSSIGLQAGNKGASQAGMSMGAVRHVSDIRADDMSKDS AGSIGLQAGSNKGASQAGMSMGAVRHVSDIRADDMSADSAGTIGLQMGSNKGASQAGMSM GAVRHVADIRADEMSDSAGTIGLQMGSNKGASQAGMAMGSVRHVADIKTEAGEGQGMIGL QMGTNQLASQSGMSMGATRHVADIKTGAGEGQGVIGLQMGSNVGASQAGMSMGKQRMV-- -AHSFGTDPITCHAWNKDRSQIAVPNSSNVIIYTLRWEETAVLKEHTQRVTGIDWAVNSN LIVTCSADRNAYVWPTLVILRINRAATCVKWSPKENKFAVGSGARLISVCYFEKENDWWV SKHIKKPIRSTVTSIDWHPNNILIGCGSTDFKARVFSAYIKDIEDKPSATVWGKKMTFGN LMAEFSNGGGWVHYVAFSASGDKLAWVGHDA----------------------------- ------------------------------------------------------------ --------------------------DGYVGFANLPNQVYRKSVKKGFEFTLMVVGESGL GKSTLINSLFLTELYNSDYPGPSHRIKKTVQVEKTQVLLKEGGVQLRLTVVDTPGFGDAV DNSNCWQPVIDFIDANYDEYLNSESRVNRKTNPDSRVHCCLYFIAPNGHGLKPLDVEFMK RLHDKVNIIPMIAKADTMTPDECRDFKKTILNEIAQHKIKIYEFDDEEENKVQKRLKDRV PFAVVGSNTVVENSGKKFRGRVYPWGVVEVENLEHNDFIALRNMLIRTHMQDLKDVTNNV HYENFRYNKLASVSKNPLTQMDDEKKEHVQKLKKKEAEMEQVFEMKVKEKQQKLKNSEND LQRRAEQMKKSLEQQQKELDLKQEQFEKEKAQWEEQAR---------------------- -AMEAVGHAGSCLGILAEDGVLLVAERRNTNKLLDEVSYSEKIYKLYDDLACSVAGITSD ANVLTNELRLIAQRYMLQYQEPIPCEQLVSTLCDFKQAYTQFGGKRPFGVSILYMGWDKH YGYQLYQSDPSGNYGGWKATCIGNNSAAAISMLKQEYKE-EGKLSDALKLSLKVLSKTLD MTKLTSEKIEMTTLTRENGVTQIKILQNADVDELIKAHEAEEAKIEAEKKQELNEAWERL RQLSLQRQERLYGAHEIQHFNRDADETIAWITEKEAIISSDDYGRDLASVQALQRKHDGV ERDLNALEEKVKTLSGEADRLCDSHPDQQDQIRQKQTEIAQDWDRLSGKAAERKSRLDDS YYLHRFLAEYRDLISWIYDIKAIISADDLAKDVAGAEALLERHQEHKGEIDAREDSFRAT AEAGQKLLESEHYAVEEVKEKLVTLANEKTGLLDLWEERRILYEQCMDLQLFYRDTEQAD TWMTKQEAFLTNEDLGDSLDSVEALIKKHEDFEKSLAAQEEKIKALDEFATKLIENEHYA ADDVAQRRDALLARRNALYEKSTLRRHMLEESYRYQIFERDYDETKGWINEKLKTASDES YMDPTNLQGKVQKHQNFEAELQANQSRIEGVTKTGGELIESDHFAKEQIRDHLDELQSLW AQLVEQSERKGSKLKDASDLQQYNRNVEDLEVWLAESEGVITSEDLGK------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------ERLTAMG QTEAAEKIRVQIEDLNQRWAALQQVTAERAETLASSHETQRYHRDVDETLDWIEEKSRAL DTTDYGKDLATVQRLQRKHEGLERDLAALGDKVRQLDQDAHRFMESHPDQAEEIYKHQTE VNEKWNTLTTKAEARKTKLLDSYDLQRFSSDYRDLMSWINSMMALVSSEELAKDVTGAEA LLDRHQEHRMEIDARAGTFQAFEMFGHQLLQNDHYAADEVKEKLTELAESREALEKAWVD RRQKLDQNLEMQLFNRDCEAADSWMSIREASLQAGQGEDDNVDGLIKKHEDFDRAIKTQE EKIYALQNFATQLTEGDHYDKDSIHGRRDEVLNRWDNLKTAMIDNRSKLGEAQTIQQFVR DADEMDSWITEKLQSAMEESYKDPTNIQSKHQKHQAFEAELAANADRLQTVIQTGQRLLD EGKCAGSEEAVKQRLAALTEQWEYLVTKSSEKSEKLKEANRQRTYNAGIKDIDFWLGEVE HMLETDDYGKDLASVQNLVKKHQLLEADIKAHEPRIDDLNKIADTFIEAGVWDADKIKDT KDQINDRYQKVCDAAEQRRLRLDEANTLHQFFRDIDDEESWIKEKKLLVGSDDYGRDLTG VQNLRKKHKRLEAELT------XAVQNVGEKLIADSTIGTQEIENRLKQLSDNWNDLKAL ADNRSKKLEESYAFQQYSASIEEEESWITEKQHLLSGDDYGDTLAAVQGLIKKHDAFDTD YQVHKDRSSEIYKDGDKLIEEGNHNADNIATRCKGLQEKMNVLETAATTRKARLIDNSAF LQFIWKTDVVESWIADKETQVRSDDYGRDLSSVQTLLTKQETFDAGLQAFEKEGIQTITS LKDQLLEANHAQTPAIQKRYNDVIERWQKLLSDSEARKQ--------------------- ------------------------------LREAHDQFKTSLSAAKTDFEQLADLDRKIK SFHVGPNPYTWFTMEALEDTWHNLQKIIKERDNELEREQQRQEENDILRKQYAEAANQFH RWLTEXX-----------XXXXATKGKSAEVRAQRGQLKHIEDLSAQMEERLILDNRYTE HSTVGLAQAWDQLDQLGMRMQHNLEQQIQARNTSGVSEDALREFSMMFKHYDKDKSGKLN HHEFKSCLRALGYDLPMVEDGQRDPEFEAILDSVDPNRDGYVSLQEFMAFMISRETENVQ SASEVEQAFRALTAGEKPYITANELYANLTKEQ--------------------------- --------AIRCYQCDSNEDSSCPSHRPFDTTVNALTDCSSFEAKTPGTFCMKIVQESPG WGGWIKITRRCGSRADQGVAWGCRWFWEENGVWKEVCYCDNYDGCNSSS----------- ------------------------------------------------------------ ------------------SKYEEMYAPEIADFVYITDNAYSKSDIRKMEILILKTLEFNL GKPLPLHFLRRNSKAGQVDPTKHTLAKYLMELTITDYESVQYTPSQIAAGALCLSIRTLD WSDTLHHYSNYSEENLMPVMRRMATLIMKKLQAIRTKYSTSKFNKISSIPQLKSSVITDL -----------NNPSPGPENDLERVFVWDLDETIIIFHSLLTGAYSQRYGKDPPSAVSLG LRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSNYNFQTDGFHAAATNNLCL ATGVRGGVDWMRKLAFRYRRIKEMHNSYRNNVGGLLGVQKREAWLQLRSEIEALTDSWLT LALKSLNIINSRSNCVNVLVTTTQLVPALAKVLLYGLGGVFNIENVYSANKIGKESCFER IVSRFGRKCTYVVIGDGRDEEVASKQINWPFWRISNHSDLAALYHVLDLGYL-------- ---------------------IVKTSLGPVGLDKMLVDDVGDVTITNDGATILKLLEVEH AAAKVLVELADLQDQEVGDGTTSVVIIAAELLKNADELVKCKIHPTSVISGFRLACKEAV KYIQEHLTISTDDLDKNCIINCAKTSMSSKIIGADSEFFSAMVVDAANAIKMADGKGGYR YPIKAVNVLKAHGKSSRESILVNGYALNCTVAAQGMPKKVANAK---------------- ------------------------------------ILTTGGIDDLCLKYFVEGGAMAVR RCKKVDLKRIAKACGGQLVLTMANLEGEESFEPSMLGQADEVEQVRICDDELILVKGSKA RTAASIILRGANDFMVDEMERSVHDALCVVKRVLESKSVVPGGGAVEAALSIYLENFATS LSSREQLAIAEFAHS-------------------------------------KFKWFGLD LVNGTLRNNMEAGVVEPSISKIKSIRLATEATVTILRIDDFIKLHPEPP----------- ---EDPNARILASKNILNEYLVEGKDLTVEYYLYNVGASAALNVQLADYSFPEGDFEVVR GFLNAQWERLAPGSNVSHAVIVRPLKSGYFNFTSAEISYLSAEDEPTLAYTSAPGEGGII SLKDYDRKFSPHIVDWATFALMCLPSLGIPLLLWYSSKSKYDAPKAKKNSGGSHKDLTEK YRVILEIVDAVKIFIEAIVNENVSLVISRQILSELCNNVTKLDDTISMDVSHFILEKIQP RVISFEEQVASIRQHMAEMYEREEKWNKAAVTLVGIPLETGQKQYSNDYKLETYLKIARL YLEDEDPVQAEAYINRASLLQADSQNEQLQIYYKVCYARVLDFRRKFIEAAARYNELSYK TIIAEDERVHALKSALICTILASAGQQRSRMLATLFKDERCQQLPAYSILEKMYLDRIIR SSDLQEFSALLLSHQKATTSDGSTILDRAVIEHNLLSASKLYNNISFEELGALLEIPPAK AEKIASQMITEGRMNGYIDQIDSIVHFEAREALPTWDKQIQNLCLQVNDIIEKISTHAPE WMAKANDEQMT-----------------RENNQPINKIAFSANGELLISSSYDDQIVIYD CQGGKCTRNLNSKKYGVDLINFTHTQNTAVHSSTKIDDTIRYLSLHDNKYIRYFGGHTKK VVSLSMSPIDDTFISGSLDNTIRLWDLRSPNCQGLMHLPGRPV----------------- ---------------------------------SPDGKLVLISTSGQIIRLIDSFQGTPL QTFMGYMNNRGLPIEASFSPDSQFVFSGSSDGKIHSWNTDTGAKVAVLNSEHQGPV---- ------------------------ENILVEKRGEKKNVGLIQLNRPKALNALCDALMKEL GTALDEFEKDPEVGCVVLTGSEKAFAAGADIKEMQGLTFSQTFGGGFLNHWNRLASNKKP VIAAVNGFALGGGCEVAMMCDIIYAGEKAKFGQPEILLGTIPGAGGTQRLPRAIGKSKAM EMALTGDMINAADAEKAGLVSKVFPPGELVDAAVKTAEKIASHSKLIVAMCKESVNTSYE LTLNEGMHFEKRIFHATFATKDRKEGMTAFVE-------- >Owenia_fusiformis_DE MTERKAVIKNADMSEDMQQDAVDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSG-----RCFQTSATQRDIDQAAKFIGAGAATV GAAGSGAGIGSVFGSLVIGYARNPSLKQQLFSYCILGFALSEAMGLFCLMMAFLILFAFM SHYKETGKAPEATIHRIRITLTSRNVKSLEKVCADLIHGAKEKNLKVKGPVRMPTKTLRI TTRKTPCGEGSKTWDRYQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX X------QKRKFVADGVFKAELNEFLTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVL GEKGRRIRELTSVVQKRFNFPEGTVELYAEKVATRGLCAIAQCESLRYKLIGGLAVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPINDYVDTAVRHVLLRQ GVLGIKVKIMLPWDPNGKIGPKRPLPDHVSIVEPKEEEIPTTPISEQKGGKXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXRKGKAKVITLGPQVADGENVFGVAHIFASFNDTFVHVTDLSGKETITRVT GGMKVKADRDEASPYAAMLAAQDVAERCKVLGITALHIKLRATGGNRTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRLXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--- ATIRTRKFLTNRLLARKQMIVDVLHPGRATVPKTEIREKLAKMYKTTPDVIFCFGFRTQF GGGKTTGFGLIYDSLENAKKFEPNYRLARQGSRKQRKERKNRQKKVRGTAKAKIG-XXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRMHAPGKGISQSALPYRRSVP TWLKLTSEDVKEQIYKLSKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKAKGMAPE IPEDLYHLIKKAVAMRKHLERNRKDRDSKFRLILVESRIHRLARYYKKKRVLPPTWKYES STASALVAVAEVPEIKLFGRWATDDVQVSDISLTDYIPVKEKYAKLLPHSAARYQVKRFR KTQCPIVERITSSLMMHGRNNGKKLLTMRIIRHALEIIHLLTGENPLQVLVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGARESAFRNIKTIAECLADELINAAK GSSNSYAIKKKDELERVAKSNR--EQMTLRGTLQGHEGWVTQIATSAQCPDMTLSASRDH SLIMWKLTRDTNYGIPQKCLKGHNHFVSDVVMSSDGQFALSGSWDTTLRLWDLSTGVTTR RFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIDESHSEWVSCVRFSPNT IVPVIVSCGWDRLVKVWNLTNCKLKTNHIGHTGYLNNVTVSPDGSLCA------------ ------------------------------------------------------------ -----------------------------------XXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---LPMNPKPFL NGLTGRPVMVKLKWGMEYKGYLVSVDGYMNLQLANTEEYIDGALSGNLGEVLIRCNNVLY IRGVDEE-EEGEMKEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMAAIRKKLVIVGDGACGKTCLLIVFS KDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCYSI DSPDSLENIPEKWTPEVKHFCPKVPIILVGNKKDLRNDENTKRELMKMKQEPVRPEDARV MSDKIDAFAYLECSAKTKDGVREVFETATRAALQVKKKQR--XXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------ILKPGGEKPDEFESSISQ ALLDLEMNSDLKAQLRELNITGAKEIDVQGKKAIIIFVPVPQLRLYQKIQTRLVRELEKK FSGKHVVFIAQRRILPKPTRKTKSKSKQKRPRSRTLTAVHDAILEDLCYPAELVGKRIRI KLDGSRTIKAHLDKTQQTNIEHKVDTFTAVYKKLTGKDVVFEFPENLLXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSGGLSA LTLKEEDVTKFLACGTHLGATNCDFQMESYVFKRKPDGVYIINVRKTWEKLLLAARAIAA IENPADVCIISARPYGQRAVLKFAHYTGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDP RTDHQPLTEASYVNIPVVALCNTDSPLRHVDVAIPCNNKGSHSIGLMWYLLAREVLRLRG TISREVPWDVMVDLFFYRDPEEVEKD---------------------------------- -------MKFNKMVSGSRAKNRKRHFNAPSHIRRKIMSSPLSKDLRAKYNVRSIPIRKDD EVQVVRGHYKGPQYGKVVQVYRKKFVIHIERIQREKANGASVNVGIHPSKVVIVKLKLDK DRKSILERKSRSRQVGKHTEETI----ATNVGSTVRQRKTTSAAGSAAGMWRFYTEDSPG IKVGPVPVLVMSLLFIASVFMLHIWGKYTR-XXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------QLTPQ EIRDLKIVFDTFDGNSDGYLNVVEFRKAFKVLGFRINKKVAKQMVTDVDLRKKGAIEFNE FLEFVIERQMDRDVKAEIMQGFDMFDYDKQNKISMDNLKQACRETGVKFSIQELEEADAN GDSFIDPAEFERVMVQTNLF------------------------------------KLGA RRIHTVRTRGGNKKCRALRLDTGNFAWGSESQARKTRIIDVLYNASNNELVRTKTLVKNC IVHIDATPFRQWYEAHYALPLGRRKGTKMNEEDEARIDKRSKKTQKKYDERQKVAKIESA LEDQFSAGRVLACVSSRPGQCGRCDGYILEGKELEFYLRKIKAKKGKXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXX-SGTESDSDDSMPDLEDVAAAAGITEEMVSKAKQSRSEKKS RKAMSKLGLKQVTGVTRVTIRKSKNILFVISRPDVFKSPASDTYIVFGEAKIEDLNQQAQ MAAAEKFKTEEEIDEGGVEGKDIELVMSQANVSRGKAVKALKHNDNDIVNAIMXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------KQPTIFLNKKKALVERFVR SVGLGFETPREATEGTYVDKKCPFTGKINIRGRILSGIVFKMKMQRTIVIRRDYLHYVKK YNRFEKRHRNMSVHCSPAFRDVAVGDIATVGECRPLSKTVKYNLLKVTKTAAGKKAFAKF MVNIPKQRTTFCKGKNCKKHCLHRVSQYKTGKASLVSQGKRRYDRKQKGYGGQTKPIFRK KAKTTRKIVLKMECTVCKYRKQLPIKRTKHFELGGDKKKKGQMIQFMGRVIRSQRKGPGS VFTAHTKHRKGAAKLRAIDFAERHGYIKGVVKDIIHDPGRGAPLARVMFRDPYRYKMRTE TFVATEGMYTGQFVYAGKKATLQVGNILPVGGMPEGTVVCCIEEKTGDRGKLARASGNYA TVISHNPDTKRSRVKLPSGSKKVIPSANRAIVGIVAGGGRIDKPLLKAGRAYHKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGHASTVKRTTSAGRKVGLNAARRTGRLKGSKSSQG K-KRTKKAGIVGKYGTRYGASLRKLIKKMEVTQHGKYTCSFCGKESMKRKAVGIWNCKAC RKTVAGGAYVYSTTAAATVRSAVRRLRETKEMGRRPARCYRYCKNKPYPKSRFCRGVPDA KIRIYDLGRKKARVDDFPLCIHMVSDEYEQLSSEALEAARICANKYLVKNIGKDAFHCRI RLHPFHVIRINKMLSCAGADRLQTGMRGAFGKAQGTVARVNIGQPIMSIRARDGARADVI EALRRAKFKFPGRQKIHISRKWGFTKWDREDYDVMRADGRLIPDGVSVQYKPHRGPLQAW KNRQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGAYKYIQELWRKKQSDVMR FLLRIRCWQYRQLSSIHRAPRPTRPDKARRMGYRAKQGFVIYRVRVRRGGRKRPVPKGAT YGKPTNQGVNSLKYQRSLQSTAEERVGRRCGGLRVLNSHWVSEDSSYKFFEVIMVDPFHK AIRRDPDTQWITKPVMKHRELRGLTSASKKSRGLGKGHGYNKTTGGSRRANWKRQNMLSM RRKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXLSFVENFALSGIAAGVSKTAAAPIERVKLLVQNQDEMIKSGRLAKPYNGVIDCTV RTFKTEGILPFWRGNLANVIRYFPTQALNFAFKDQIKAAFKASNQDSHAVKFSKNIASGG VAGAMSLCFVYSLDYARTRLANDSKGCAKRQFNGLIDVYRKTLKSDGIVGLYRGFVISCV GIVVYRGCYFGFYDTLKPIMLGEDANVFMSFVLGYFVTITSGYISYPYDXIR-------- ---------------------------------------------------------XXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX VRLPPEVNRILYIRNLPYKITAEEMYDIFGKYGAIRQIRVGSTPETKGTAFVVYEDIFDA KNACDHLSGFNVCNRYLVVLYYQPNKAFKKMDTEKKKDELDAMKSKYGLSTPQKKXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--NEAGEYVDT YIPRKCSASNRIITAKDHASIQLNLAEVDDTTGRMTGQYKTYAICGAIRRMGESDDCIVR LAKKDGVIAKMPRGPRKHLKRLNAPKHWMLDKLGGVFAPKPSCGPHKTRECLPLMVFLHN RLKYALTHDECKRIDNQRLIKVDGKVRTDKTYPCGFMDVITIEKTGENFTLIYDVKGRFT VHRIKPEEAAYKLCKVKKVSVGPKGVPYIVTHDGRTIRYPDPLVKVNDSIQLXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKTEICA FSGYKIYPGHGKRVVKTDGRSFVFINSKCEKSHAMKRNPRKISWTVMYRRKNKKGQQEEL SKKRTRRTTKFQRAVAGATLTDIMAKRNQKPEVRKAQREQAIRAAKEKQRAKDAMKSRVG GKRMKLNISYPATGCQKLIEVDDDLKLRAFYEKRMAQECSAESLGDEWKGYIVRISGGND KQGFAMKQGVLVPGRVRLLLSKGHSCFRPRRTGDRRRRSVRGCIVDANLSVLNLVIVKKG EQEIAGLTDSTVPRRLGPKRASKIRKLFNLSKEDDVRQYVVRRPLAGKSKAPKIQRLVTP VVLQRKRHKLALKKKRSTKKREDAAEYAKLLAQRMKEAKERKMERRRSASHSKKVKAKDL RGKKREDLVKQLEELKQELSQLRVAKVTGGAASKLSKIRIVRKSIARVFTVMNQTQKENL 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----------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXKIAGKYSQESEAEVIGWFQALIAPGMHSVQQ TLKNGQLLCKLVQAVKAKKFKIKFNTMSAPFKQMENITVFLNACEAYGVPKNSLFQTVDL FEGRNMAQVMATILQLGTECQRTGFDGPTIGPRPTEKHIVEFSEEQLKAGQLQAGTNKCA SQAMGAVRHIADIKADDMSKDSQSTIGLQAGNKGASQAGMSMGAVRHVSDIRADDMS--- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------------MA AAHSFGTEPITCHAWNTDRSQIAVPNSSNVVIYSLRWEETAVLKEHTQRVTGIDWAGISN RIVTCSADRNAYVWPTLVILRINRAATCVKWSPKENKFAVGSGARLISVCYFEKENDWWV SKHIKKPIRSTVASIDWHPNNILIGCGSTDFKARVFSAYIKEIEDKPGATVWGKKMPFGN LMAEFSNGGRLVH----------------------------------------------- ------------------------------------------------------------ -----------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIDKNDGDNPQ LVSEYVNDIYGYMRHLEVEEVNPRMRSILVDWLVQVHLRFHLLQETLYLTVAIIDRFLQV EVSRNKLQLVGVTSM--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX >Paramphinome_jeffreysii MSDRKAVIKNADMSEEMQQDAVDCATQALEKYNIEK-IAKYVKLDCTKQYGDSWHCILGR NIDWAVRNTAGYFIEYQENGYTILVWRNG------------------------------- -----------------IAYARNPSLKQQIFSYAILGFALSEAMGLFCLMMAFLILLAL- ----------------------------------DLIRGAKEKNLKVKGPVRMPTKILRI TTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADMDQVM AYVEPGKQFAKDSIRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNII V----------------------------------------------------------- ------------------------------------------------------------ --------------------------------------IHSGDPVNDYIDSAVRHVLLRQ GVLGIKVKIMLPWDPAGKIGPKRPLPDHVSIVEPKDEPRIEAPYSEQKGGKMSKRGRGGA SGGKFRITLALPVGAVMNCADNTGAKNLYVISVHGIKGRLNRLPTAGSGDMVMATVKKGK PELRKKVMPAVVIRQRKSIRRQNGVFIFYEDNAGVIVNTKGEMKGSAITGPVAKECADLW PRIASNASSI-------------------------------------------------- -----KADRDEASPYAAMLAAQDVAERCKVLGITCLHIKLRATGGNRTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL-------------------------- -KKSHLGTRWKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP RDGCLNYIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVASVSLLALYKEKKERPRSEAV ATLRTRKFLTNRLLCRKQMVVDVIHPGRATVPKTEIREKLARMYKTTPDVIFCFGFRTQF GGGKTIGFALVYDSLDFAKKFEPKYRLARHGTRKQRKERKNRQKKVRGTKKAKVG----- ------------------------------------------------------------ ---------------------------------------------------LGLSKSIHH ARVLIRQRHIRVRKQVVNVPSYMVRLDSQKYIDFASNSPXXXXRPGRCARKNSKKNKGGG DA---------------------MVGLDAAGKTTIINKLRPGHIVTTSTTNGFNVETIEY KNIILDSWNLGGQDEIRALWREHYKNVKGLIFVMDSNDRERIGEAREEINRMLDEDELRS ATLLVFANKQDLPNAMNPAEVTDGLGLHAVRYHTWYIQAACASSGDGLVEGLDWLSQQLQ SQK-------------------------QSPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCSTVLCQPTGGRARLTEGCSFRRKQHMVRMNVLADALNSICNAEKRGKRQVLIRPCSKV IVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDISIRDMEKWTTNL LPSRQFGFIVLTTSGGIMDHEEARRKHLGGKILGFFF----------------------- ------------------------------------------------------------ --EDLYCLIKKAVSIRKHLERNRKDKDSKFRLILVESRIHRLARYYKRKRVLAPNFKYES STASALVA---------------------------------------------------- -----------------------------------------------------ITAGGPR EDSTRIGRAGTVRRQAVDVSPLRRANVAMKLLCTGARESAFRNIKTIPECLADEIINASK GSSNSYAIKKKDELERVAKSNR-------------------------------------- ------------------------------------------------------------ ----------------------------------------------HSEWASCVRFSPNT QNPIIVSAGWDKLVKVWNLTNCKLKTNHFGHAGYLNCVTVSPDGSLCASGGKDGQAMLWD LNEGKHLYTLDGGDTINALTFSPNRYWLCAATGPSIKIWDLEGKIVVDELKPEVIGTSAD PPSCISLAWSAD-----------------------MREYKLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKQVEVDCNQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKLARHFNCAFLETSAKSK ISVNEIFYDLVRQINKKNPEQMSEEKKDASEHISLKVTGQDGSVVHFKIKKNTPLRKLMS AYCDRTSVKMGAMRFIFDGNPISETDTPAGLEMDNEDTIDVFQQQTGGXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX--------------------------------------------- ------------------------------------NLIKVDDNKKLGEWAGLCKIDKDG KARKVVGCSCVVVKDYGKETQALDVLQEYFKSKRMAAIRKKLVIVGDGACGKTCLLIVFS KDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSI DSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDDNTKRELAKMKQEPVKSEEGRA MSEKISAFSYLECSAKTKEGVREVFETATRAALQVKKKKVGKXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFSASVKIVKPQGEKPDEFESSISQ ALLELEMNSDLKAQLRELYITAAKEIDVQGKKAIIIFVPVPQLRAYQKIQTRLVRELEKK FSGKHVVFIAQRRILPKPTRKTRTKNKQKRPRSRTLTSVHDNILDDLCYPAEIVGKRIRI KLDGSRLIKVHLDKNQQTNIEHKLDTFTAVYKKLTGKDVNFEFPDFVLDRGGFRGGFGGR GRGRGRGRGRGKDGEKDWIPVTKLGRLVKDLKIKSLEDIYLFSLPIKEFEIIDFFLGTAL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDFNGHVGLGVKCSKEVATAIRGAIILAKLSV VPVRRGYWGNKI----------------------------------------------XX YTSARGQTATLGNFAKATYAAIAQTYSYLTPDLWKETQFTKSPYQEFTDYLAK------- ------------------------------------------------------------ ---------------------------------------------------------TDP RTDHQPVTEASYVNIPVIALTNTDSPLRYVDIAIPCNNKGAHSIGMMWWLLAREVLRLRG TISREVPWDVMVDLFFYRDPEEAEK----------------------------------- -------MKFNKMVTSSRRKNRKRHFNAPSHIRRKIMSSPLSKDLRQKHNVRSMPIRKDD EVQVVRGHYKSQQVGKVVQVYRKKFVIHIERIQREKANGASVHVGIHPSKVVLIKLKMDK DRKRILERKARSRDKGKHTEESIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRKEGKKKSAINDVVTREYTVNIHKRIHGI GFKRRAPRAIKEIKKFAEKMMGTPDVRVDTRLNKHMWSKGIRNVPYRVRVRLARKRNEDE DSPHKLYTLVTYVPVTTFKGTQTVNVDSFIRSTAVVAAKYRLVKKIGAGSFGDIYLGVDV TNGEEIAVKMETMRSKHPQLHYESKVYKILNKGIGFPRIRWYGEREYNVMVMDLLGPSLE DLLNFCNRKLTLKTVLMLADQMVERVEYLHNKSLIHRDIKPDNFLMGIGKDCNRVFLVDF GLSKKYKDSRTRSHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFAKGT LPWQGLKAATKKQKYDKISEKKMNTRVDVLCKGCPAEFSMYLNYCRGLRFEETPDYMYLR QLFRILFRTLNHTYDFVYDWTVLRQK----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMTRYSLDPENA TKSAKARGSHLRVHFKNTRETAHAIKKMHLRRAVRFLKNVSDHKECVPFRRYNGGVGRCA QAKNHKATQGRWPMKSAEFLLQLLKNAESNAEYKGLDTDHLVIEHIQVNKAPKMRRRTYR AHGRINPYMSSPCHIEVILAEREQAISRPAKKKVSQKKLKKQKMKMRDKKTGPKPELTEE QKQEIREAFDLFDAEGTGTIDAKELKVAMR------------------------------ -XXXXXXKMSEKDSKEEILKAFRLFDDDGTGKISFKNLKRVAKELGENITDEELQEADRD GDGEINEQEFLRIMKKTSLY---------------------------------------- -------TAGGNQKFRALRLDHGNFSWGSEAVTRKTRIIDVVYNASNNELVRTKTLVKGC IVTIDATPFRSWYESHY------------------------------------------- -----------------------------------------------------------L RVMNTNIDGRRKVPFAMTAIKGVGRRYAHIVCKKADVDVSKRAGEMTDEEVEKLITIMSN PRQYKIPDWFLN------------------------------------------------ ------------------------------------------------------------ --------LRPGTGVSRVTIRKSKNILFVINRPDVYKSPASDTYIVFGEAKIEDLSQQAQ MAAAEKFKAEEEVEESGIEAKDIELVMSQANVSRAKAVKALKNNSNDIVNAIMMGRVRTK TVKKAARVIIEKYYTRLTLDFHTNKRIAEEIAIIPSKKLRNKIAGFVTHLMKRIQRGPVR GISIKLQEEERERRDNYVPEISAIEEVDPDTKEMLKMLDFGNIPNLQVTQPITTSMKWEY KEEHAFEKRRAEGEKIRKKYPDRVPVIVEKAPKARVGDLDKKKYLVPSDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGALYQEHHEEDFFLYIAYSDESVYG--------- ------------------------------------------------------------ ------------ELRKNNFSKTGNFGFGIQEHIDLGIKYDPGIGIYGMDFYVVMARPGFN VAYRRKKTSKIGSKHKINKEETMRWFQQKYDGVILPGK---------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------LIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVN TGRGTEFEGAIIALFHLLATRQDKVRGLREAFYRQNLPNLMNLM---------------- ------------------------------------------------------------ ------------------------------------------------------------ ---SAKDVAKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVMADFMGAIG SGTGILLAVTIIYQYFEIFVKEQSEMGGMSTLLF-------------------------- ----------------------PFTGNVSIRGRILTGVVTKTKMQRTVVIRRDYLHYVRK YNRFEKRHKNISAHCSPCFRDIRAGDVVTVGECRPLSKTVRFNVIKLSKGAGSKKGFQKF MVNVPKSRRTFCKGKNCRKHTLHKVTQYKKGRDSVHVQGKRRYDRKQSGYGGQTKPVFHK KAKTTRKIVLKMECSECKFRKQVAIKRCKHFELGGDKKKKGQMIQF-------------- ------------------------------------------------------------ -----EGMYTGQFLYCGKKANLQIGNVLPVGTMPEGTIICNLEEKMGDRGRLARASGNYA TVVSHNPDTRRSRVKLPSGSKKVIPSNNRAMVGIVAGGGRIDKPMLKAGRAYFKYKAKRN CWPK-RGVAMNPVEHPHGGGNHQHIGKASTVRRDTSAGRKVGLIAARRTGRLRGTKIIVQ KAKRTKKVGIVGKYGTRYGASLRKTIKKLEVSQHGKYTCSFCGKETMKRRAVGIWTCKSC RKTVAGGAWVYSTTAAATVRSAVRRLRETK----------------------FCRGVPDS KIRIYDLGRKKAGVDEFPCCIHLVSDEYEQLSSEALEAARICANKYLVKHCGKDAFHLRM RPHPFHVVRINKMLSCAGADRLQTGMRGAYGKPLGTVARVRIGQTVLSVRTRVNNSERVI EALRRAKFKFPGRQKIYVSNKFGFTKYTQEVYKQYLAEGKLIPDGSNVQYKPDHGPLKLW MMRV--------------CIRGKVKFIEKTSRSLVHPWKGEVYRGN-------------- -MTKGTSSFGKRHNKTHTICRRCGRSAYHIQKKTCARCGYPAQRIRRYNWSIKAKRRKTT GTGRMRHMKTVYQRFRNGFREGTVAKPKRK------------------------------ ------------------------------------------------------------ ---------------------------------ITQVYGFYDECLRKYGNASVWKYFTDL FDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHSNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRC GNQAAIMELDDALKYSFLQFDPAPRRGEPHVTRRTPDYFLMGAYKYMQELYRKKQCDVVR FLLRVRCWQYRQLSSIHRASRPTRPDKARRLGYRAKQGFVIYRIRLRRGGRKRPVPKGAT YGKPTNQGVNQLKFQRSLQSVAEERVGRRCRALRVLNSYWVAEDSTYKFFEVIVVDPFHK AVRRDPNYQWICKPTSKHREMRGLTSAGRKSRGLGKGHKFHSTTGGSRRANWKRRNSLQV RRKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------ ------------FDKHMNLILGDCDEFRKVKPKTAKQREEKRTLGLVLLRGENLVSMTVE GPPPAEEGIARVPIPGATGGPGMGRAAGRGVPSAGGLQGPVRGLGGPSSQMMQPQ----- ---P-----FKLVLVGDGGVGKTTFVKRHLTGEFEKKYVATLGVEVHPLIFHTNRGPFRF NVWDTAGQEKFGGLRDGYYIQGQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCG NKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLVGDPNLEFVEMPA LAPPEVQFDPQLAAKYEQELQEAQDVALPDEDEE-------------------------- ------------------------------------------------------------ -------------------------------------MVEKVPDSTYEMVGGLDKQIKEI KEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ KFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRLEGGSGGDSEVQRTMLELLNQLD GFEPKQNIKVIMATNRIDILDSALLRPGRIDRKIEFPAPNEEARLDILKIHSRKMNLTRG INLRKIAEMMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFELAVAKVMQKDSEKNMSI KKLWKLSFVENFALSGCAAVISKTAAAPIERVKLMVQNQDEMIRIGVLEKPYKGVVDCTV RTFKSEGVLPFWRGNLANCLRYFPTQALNFAFKDQIKKVFKSGSKDSYGLKFTKNVASGG AAGAMSL---------------------------------XXXKSDGIVGLYRGFVISCV GIIVYRGCYFGFYDTLKPLLLGDDAGLAISFALGYVVTISAGLVSYPIDTIRRRMMMTSG QAVKYKGSMDCFLTVVKTEGPLTLMKGAGANILRGVAGAGVLAGFDKFKELYISMRL--- ---------------------------------------------ITAGGDIHGQFYDLK ELFRTGGELPETNYIFMGDFVDRGYYSLETFTLLLSLKARWPDRITLLRGNHESRQITQV YGFYDECQTKYGNANAWRYCCQVFDLLTVAAIIDECILCVHGGLSPDIKTLDQIRTIERS QEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKTICRAHQLVHE GYKYMFDEKLVTVWSAPNYCYRCGNIAAVLAFSDSDHKEAKLFRAVPDSER--------- ----------------------------------IRQIRMGNTPETKGTAFVVYEDIFDA KNACDHLSGFNVCNRYLVVLYYQSNKAFKKMDQEKKKEELDIMKAKYGLSTPEKKMSIGV PIKVLHEAEGHVVTCETNTGEVYRGKLVEAEDNMNCQMSNITVTYRDGRVAQLENVFIRG SKIRFLILPDMLKNAPMFKRVGAGRGKSAILRAAARGRGRSSGRGG---MQSEQGEFVEM YIPRKCSASNRIIQAKDHASIQINFAEVDETTGRMTGQYKTYAICGAIRRMGESDDCIAR LAKKDGLIAKMARGPRKHLKRLHAPKHWMLDKLGGVFAPKPSTGPHKMRECLPLMVFLRN RLKYALTYDEVKKIVNQRLIKVDGKVRTDKTYPTGFMDVVTIEKTSENFRLIYDVKGRFT VHRIQPEEAKYKLCKVKRVCMGPKGVPYIVTHDARTIRYPDPLTRINDSVQVMGTKDDEY DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTA GQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADNNIVIMLVGNKSDL RHLRAVPTDEARAFAEKNNLSFIETSALDSTNVETAFQNILTEIYKIVSQKQIRDSPDDN NVQTITVAPTDNSADRKKPCCS--SRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVR GKDIVALGVEKKAMAKLQEDRTVRKIGLLDDHVAMAFAGLTADARILINRARVECQSHKL TVEDPVTLEYITRFIAQLKQKYTQSNGRRPFGLSTLIIGFDGTPHLYQTDPSGTYHEWKA NAIGRSAKTVREFLEKHFTDETASEKEVIKLTLKALLEVVQSGSKNMEVAVMRKNQPLQM LESEELEKYIKEIEKEKEEEAEKKKQK------------EKKRKYEPPVPTRVGKKKKKL KGPEAANKLPQVTPHTRCRLKLLKLERIKDFLLLEEEFIKNQERLKPQEEKQEEERSKVD DLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSIFSFVDKDQLEPGCSVLLNHKVHAVV GVLGDDTDPMVTVMKLEKAPQETYADIGGLDAQIQEIKESVELPLTHPEYYEEMGIKPPK GVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPS IVFIDEIDAVGTKRYESNSGGEREIQRTMLEL---------------------------- ------------------------------------------------------------ ----------------------------------------KRKPYSPFQDSNYSEYALAR VDDLVNWARKSSLW-----------------------------------QADCMIVAGTL TNKMAPALRKVYDQMPDPRWVISMGSCANGGGYYHYAYSVVRGCDRIVPVDIYVPGCPPS AEALLYGILQLQKKIKRMKRAQSWYRQ-DFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYA NNSNYKNDTMIRKEAYVHKSVMDELKRIIEDSEVMLEDDSLWPPPDRVGRQELEIVIGDE HISFTTSKIGSLVDVNQSKDPEGLRTFYYLVQDLKCLVFSLIGLHFKIKPIXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMTEYKLVVVGAGGVGKSA LTIQLIQNHFVEEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGF LCVFAVNNTKSFEDINQYREQIKRVKDADEVPMVLVGNKVDLPTRTVETKQGKMLADTYG IPYVETSAKTRQGVDDAFYTLVREIRKYMGDRYNIHSQLEHLQSKYIGTGHADTNKWEWL TNQHRDSYSSYMGHFDMLNYFSLVENEAKARVRFNLMEKMLQPCGPPPERPED------- -------------------------NAKCEKSHRAKRNPRKVNWTVLYRRKHKKGQTEEI TKKRTRRTTKFQRAITGASLSDILAKRNQKPEVRKAQREQAIKAAKEKQRAKEGAKPRVG GKRMKLNISYPATGCQKLIEVDDEHKLRTFYEKRMAAEVTADHLGDEWKGYVVRIAGGND KEGFPMKQGVLSTGRVRLLLAKNHSCYRPRRSGERKRKSVHGCIVDSNLSVLSLVIIKKG EKDIPGLTDTTVPRHLGPKRASKIRKLFNLSKDDDVRQYVVRRPLPPRTKAPKIQRLVTP LVLQRKRHRLALKRRRASKKREDAADYAKLLAQRMKEAKERKQERKRSASHSKKVKAKEL RGKKKEELLQQLDELKTELSQLRVAKVTGGAASKLAKIHVMRKSIARVHTVINQTQKENL RKFYKPKDLRPKLTRAMRRALTKHELSCKSVKQIKQQRLYAKRRYAVK------------ -FDITIGGKDVGRIVIGLFGKTVPKTAENFKKLALGTETYKGSKFHRVIKDFMIQGGDFT RGDGTGGRSIYFADENFKLKHYGAGWMSMANAGKDTNGSQFFLTTKMTSWLDGRHVVFGK V----------------------------------------------------------- --------------------------------KSKIVITSDVPFSKRYLKYLTKKYLKKN NLRDWLRVVASTKDAYELRYFQINNEEEEEED---------------------------- -------------------------GPGQFAENETNEINFREIPSHVLQKVCMYFTYKVR YTNSSTEIPEFPIAPEIALELLMAANFLDC---YTLQQVSYHCTPQSCWIILWDKVYDIT DFIAQHPGGEDILLEHAGRDATIAFKETGHSRDALLMVKEYYIGHLVEMDR--------- --------------MSYMLQHLKNGWQVDQAIMSEEDRVIVIRFGHDWDPTCMVMDETLY KCAEKMKNFSVCYLVDITAVPDFNKMYELYDPCTVMFFYRNKHIMIDLGTGNNNKINWCM EDSQEFVDIVETVYRGARKGRGLVVSPKDYSTKYRYKKLQRQLEFLEVQEEYIKDEQKNL KKEYLHAQEEVKRIQSVPLVIGQFLEAVDQNTGIVGSTTGSNYYVRILSTIDRELLKPSA SVALHKHSNALVDVLPPEADSSITMLAADEKPDVAYCDIGGMDIQKQEVREAVELPLTHF DLYKQIGIDPPRGVLMFGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVR DVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTVNVKVI MATNRADTLDPALLRPGRLDRKIEFPMPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPD KISGADINAICQEAGMQAVRENRYVVLAKDFEKGYKNN------------XXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXSRRV--LSEDLRNVEFETSEDVEVT------------------XG FEKPSAIQQRAIKPIVKGRDVIAQAQSGTGKTATFSISILQCLDTQVRETQALILSPTRE LATQIQKVILALGDYMSVQCHSCIGGTNVGEDIRKLDYGQHVVSGTPGRVHDMIRRRNLR TRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVLLISATLPHEILEMTSKFMTDPI RILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKM REANFTVSSMHGDMPQKEREAIMKEFRSGASRVLITTDVWARGIDVQQVSLVINYDLPNN RELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLIMALRRP FDPVAHELDPNFRLTKFSDLKGGCKVPQEVLLKLLEGL-QAQEAEQSHFQYVAAVPRIGI GMDSCVTPLRHGGLSLVQTTDFFYPLVDDPYMMGKIACANVLSDLYAMGVTECDNMLMLL AVSNKMTEKERDVVVPLMIRGFKDLADEAGTSVNGGQTVINPWMTIGGVATTVCQPNEFI MPDNAVVGDVLVLTKPLGTQVAVNAYQWLDQADRWNRIKLVVSEDDVRKAYQRAMFSMAR LNRTAARLMHKYNAHGATDVTGFGLLGHANNLARIQKNEVGFVIHNLPIIAKMAAVSKAC GNMFGLLQGHSAETSGGLLIALPREQAAAFCKDIEKQEGYQAWIIGIVEKGTRSARIIDK PRVIEVPAKEKE----ILSTVDCYFINIDAHAEECFFDKVTSGTKMSLMFEVAEGGFLDI DVKILGPDGKQI------------------------------------------------ ------------------------------------------------------------ -----------------MAATLKPYLSAVRHTLTAAMCLENFNSQVVERHNKPEVEVRSS KELLLTPVVISRNEREKVLIEGSVNSLRISIAVKQADEIEKILCHKFMRFMMMRAENFVV LRRKPVEGYDISFLITNFHTEQMYKHKLVDFIIHFMEEIDKEISEMKLAVNSRARISAEE FLKQFSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVEDRLV TMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTMPNTFKTLDSWRDEFLIQASPRDPEN FPFVVIGNKIDLENRAVSTKRAQGWCHSKGDIPYFETSAKEAINVEQAFQTVAKNALAQE TEVELYNEFPDQIKLTNDTNKEGCGCSAPFDARFPNQNQTKNCWQNYVDYQRCLKVEAVE SCTYFRRLYKSLCFAEWHKKWDEQLESGTFPAKIMPDHLGSDQRKVRDEDEVEKPIQALD EGDIALLKSYGAGMYSAAIKKIEDDTQNILKRVNELTGIKESDTGLAPPALWDLAADKQT LQSEQPLQVARCTKIINADSDDPKYIINVKQFAKFVVDLSEQVAPTDIEEGMRVGVDRNK YQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIDKLREVVETPLLHPERFVNLGI DPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMART KKACIIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDT LDPALTRPGRLDRKVEFGLPDLEGRSHIFKIHARSMSVEKDIRYELLARLCPNCTGAEIR SVCTEAGMFAIRARRKMATEKDFLEAVNKVIKAYAKFSATPRYMTYNMGKEKQHINIVVI GHVDSGKSTTTGHLIYKCGGIDERTIAKFEKEASELGKGSFKYAWVLDKLKAERERGITI DISLWKFESTNYYITIIDAPGHRDFIKNMITGTSQADCAVLVVAAGTGEFEAGISKTGQT REHALLAFTLGVKQLIVAVNKMDSTQPKFSQDRFEEIKKEVSTYIKKIGYNPATVAFVPV SGWHGDNMINM------------------------------------------------- ------GTMKPGNIVTFAPTNVTTEVKSIEMHHSTLTEALPGDNVGFNVKNVSVKDVKRG NVCGDSKDDPPKEAATFHAQVIILNHPGEIHAGYAPVVDCHTAHIACKFTEIKEKNDRRS GKKLEENPKFVKSGDAAMVMMTPSKPICVEAFSDYPPLGRFAVRDMKQTVAVGVIKTVEK TTGEKGKITKAAQKA--------------------------------------------- -----------------------------GKLIVWDGYTTNKVHAIPLRSSWVMTCAYAP SGSYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIVTSSGDMTCA LWDIETGQQTTSFTGHTGDVMSLSLAPDMRTFVSGACDASAKLWDIRDGMCKQTFSGHES DINAITYFPNGYAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLG GYDDFNCNVWDTLRQERAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKIWNMSYAYLF KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES FRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARR DVKKEEGEAFAREHGLVFMETSAKTAANVEEAFINTAKEIYQRIQDGVFDINNEANGIKI GPQHSPTNPSGGGGANAGGG---------------------------------------- -------------------------------LYIMTLGCLAPYRRLGIGTVMLHHVLKIC EEDANFDNVFLHVQVNNEGAIKFYEKFGFEIVEQKQNYYKRIDPADAFVLQKTFRKMPRQ IMEIKDFLLTARRKDAKSVKIKKNVKFKVRCSRYLYTLVISDREKAEKLKQSLPPGLAVK ELKMSKISRELLLEAVNTVLTKKRKFTETVELQVALKNYDPQKDKRFSGTVKLRHIPRPK MRICILGDAQHCDEAKANEVSCMDADALKKLNKNKKLVKKLAKKYDAFLASDSLIKQIPR ILGPGLNKVGKFPTPLTHTEHMTGKIDEVKATIKFQMKKVLCLAVAVGHVGMTSEELTSN ITLSINFLVSLLKKNWQNVRSLYIKSTMGPAQRIYMADTDKLNIDSIIARLLEVRGSRPG KNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLNAGRPVTPPRGSAKSK GKMMFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEVAGTNVSTT YITCPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPF ICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDEL PAEFKLYLPVQNKMSDSKIENLKDPFGDADIIHIRIQQRNGRKTLTTVQGLSDDYDKRKI ARCCKKEFACNGTVVTHPEYGQVIQFQGDQRERVRDFLVNMGFKDQIKVHGFSAIFNFQS LLTVVLLLICTCAYIRSIAPRMLDKNKEGLLGIFWKCARIGERKSPYVAVCCIAMAVSIL FFSATRITAVLARQLPRAVSQKNSLAAGFVACRNFSTSMEVSSILEERILGESKADLEET GRVLSIGDGIARVYGLKNIQAEEMVEFSSGLKGMALNLEPDNVGIVVFGNDKLIKEGDIV KRTGAIVDVPVGLEILGRVVDALGNPIDGKGPLGASSRQRVGAKAPGIIPRISVKEPMQT GIKAVDSLVPIGRGQRELIIGDRQTGKTAVAIDTIINQKRFNEGTNEKDKLYCIYVAIGQ KRSTVAQIVKRLTAADAMKYTIIVSATASDAAPLQYLAPYAGCAMGEYFRDNGKHAVIIY DDLSKQAVA--------------------------------------------TALPIIE TQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTKAMKQVAG SMKLELAQYREVAAFAQFGSDLD--------------------------------VXXAG VKGHLDKVDPARITQFEIEYLQHVKTQHQDLLNTIREDGKITDATDAKLKKMVVDFVAVF XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXX---------------------LDELDQKMREAETDP HEGKRKVEALWPIFRIHHQKSRYIYDLFYRRKAISKELYEYCLKEAIADRNLIAKWKKQG YENLCCLRCIQTRDTNFGANCICRVPKAKLEEGKIVECVHCGCRGCSGEYAQVTKMLGNG RLEAMCFDGSKRLCHIRGKLRKKVWINTSDIILVGLRDYQDQKADVILKYTPDEARNLKA YGELPENAKISDNEEDNITFDEIDDILVRFLMKLSHETVTIELKNGTQVHGTITGVDVSM NTHLKTVKMTVKNKDPVQLESISIRGNNIRYFILPDSLPLDTLLIDDAPKAKARK---QK PKSEMTPEELSQREQEEFNTGPLSVLTQSVKNDTQVLINCRNNKKLIGRVKAFDRHCNMV LEEVKEMWTEVPKTGKGKKKSKPVNKDRYISKMFLRGDSVILVLRNPLPIIIDARGHMLG RLASIVSKTILQGQNVVIVRCEGINISGNFYRNKLKYLDFLRKRCNVKPSRGPYHFRAPS KIFWRTVRGMLPHKLKRGKFALDRMKVFEGIPPPYDKEKRMVVPAALKVLRVKPRRKFCV LGRLSHEVGWKYQTVIATLEAKRKVKSKKFYEKKKNVAKLRKQATKIAPYQKIIEGYG-X XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIFVERTLAIIKPDALSA EIEDIILRSGFSILQKRRVHLTPEQASDFYAEHYGKLFFPSLVSYMSYGPIQALVIARDK AISYWRELVGPTNTIKAKQTHPDCLRAIYGTDDQRNGLHGSDSYSSAAREIRFFFPDSVV EPIPVGQAAKDYLARAVNPTLLKGLTELCKQKPRDPVVWLADWLLDNNPNKPKVKMFEAR LVQGVLLKKVIEAIKDLLTEATWDCNGTGIGLQAMDSSHVSLVSLNLRSDGFDTYRCDRN LSMGINLTSMSKILKCAGNDDAITLKAEDNADTVTFVFESTNGEKVSDYEMKLMDRDVEH LGIPETDYSCVIKMPSAEFQRICRDLSQIGESVLICCTKEGVKFSASGDLGTGNIKLAQS ANVDKEEEAVIIEMNEGVVLTFALRYLNYFTKATPLSPQVTLSMSPDVPLVVEYKIADMG HVRFYLAPKIEDEEGA--------------GQIVAVIGAVVDVQFEDDLPPMLNALEVAG RTPRLILEVAQHLGENTVRTIAMDGTEGLVRGQVCTDVGTPIRIPVGRETLGRIINVIGE PIDERGPVNATSFAPIHAEAPEFVEMSTEQEILETGIKVVDLLAPYCKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVINLTDDTSKVSLVYG QMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTKAGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIA ELA---------------------------------IXXDYKSLQDIIAILGMDELSEED KLTVARARKIQRFLSQPFQVAEVFTGSEGRLVPLKDTISGFKQILNGELDHLPEVAFYMV GPVEEVVAKAERLAEEQ------------------------------------------- -----------------------YLTNEGIQYLRDYLHLPPEIVPSTLKRQGMGQDRQEY RKGGAGDKKAEVGAGS-MGKQNSKLKPEVLEDLRANTEFTDEEIQEWYKGFLKDCPSGHL SVDEFKKIYGNFFPYGDASKFAEHVFRTFDTNGDGTIDFREFICALSVTSRGKLEQKLKW AFSMYDLDGNGYISRQEMLEIVTAIYKMVGTVMKMPEDESTPEKRTDKIFRQMDKNLDGK LSLDEFIEGAKSDPSIVRLLQCDPMSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNL TGLNEQVPHYRQALDMILDLEPDDELEDNPNQSDLIEQAAEMLYGLIHARYIMTNRGIAQ MIEKWQQ---------------------------------------------------DG AYFGTGFPHMLYMVHPEYRPKRPANQFVPRLYGFKIHSMAYQLQFQAASNFKMGYNNGKR MTNTKGYRRGTRYMFSRKFRETGSIPLSTYLKVYKRGDIVDIKGNGAIQKGMPHKSYHGR TGRVFNVTQHAVGVIVNKRVKGRILGKRINVRIEHVRHSNCRLDFLKRVAKNEQVKKEAK -------------------------------------QTRNTYKNVSPPEPSMEWRDITE RAAVTTFWVELVKGLGIVMGNLFKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAICPAQAITIEAEPRPDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEY STETHEELLYNKEKLLENGDKWEAEIAANLQADYLYR--------------------ETQ KALEEIDACQNDIDALNEKASEEILKVEQKYNKLRKPHFEKRNDLIQKIPNFWVTAFVNH PQISAILDEE-------------------------------------------------- ------------------------------------------------------------ ------------------------------------TKSSALFYGNAFIVSAVPMWLFWR IHQMDIFILFALMT-XXXXLVAYAYKNVKFVLKHKIALKRGEAVSREVMRKVADDKKMTR QEKEERIL-------------------NALFLLFVIVASFYILKSFSPTLNYVLSIGSAG ALLALFSTSTKATQGKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQT VCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVKELQRQ ASPNIVIALAGNKADLRMVEFDEAQAYAEENSLLFMETSAKTAMNVNDIFLAIAKKLPKN EQTVDLSQDNMAEYLASIFGTEKDKVNCSFYFKIGACRHGERCSRLHNRPTFSQTILLQN LYINPQNTAQIMMNDVETQEDFDAFFEEIFIELEDKYGEIEEMNVCDNLGDHLVGNVYVK FRYEEDAEKAV------------------------------------------------- ---------------------------------------------MFLTRSEYDRGVNTF SPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVVLAVEKRVTSPLIEPSSIEKIMEVDSHIG CAMSGLIADSRTMIDRARVEAQNHWFTYNEKMSVES------------------------ ------------------------------------------------------------ ----------------------------------------------AQKTWEMSNNVENV STVDEIYHYDKKQQQDILTAKPWDKDPHYFKYIKISALALLKMVMHSRSGGNLEVMGLLL GKVDGNTMMVMDSFALPVEGTETRVNAQAQAYEYMAAYTESAKLVGRLENAIGWYHSHPG YGCWLSGIDVSTQMLNQQFQEPFVAIVVDPVRTISAGKVNLGAFRTYPKGYKPPDEGPSE YQSIPLSKIEDFGVHCKQYYSLEVSYFKSSMDRKLLESLWNKYWVNTLSSSSLLTNADYT TGQIFDLADKLEQSEAQLGRGGFMEKKSEDKLSKATKDGCKNTIEAIHGL---------- ---GGLPKRITKESLRLMSEPVPGISA--------------------KXXGGLFKLELFL PDEYPMGAPKVRFLTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPD DPLANDVAEQWK------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------DNEKNRKLFELLDVLEF NQVIIFVKSVQRCMALAQLLVEQNFPAIAIHRAMTQEERLSRYQQFKDFQKRILVATNLF GRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSD------PPSYGDLG KSARDLFNKGFNFGFYKLECKTKASNGIQFTVNGNSNHDTNKVVGNLETKYKWNDYGLTF LEKWNTDNTLGTEITIEDQLAKGLKLSFDTEFAPQTGKKSGKIKTAYKQDYINLNADVDF DFAGPTIHGAAVLGYNGWLAGYQMSFDKSKLAKSNFAVGYTTDDFTLHTNVNDGAEFGGS IYQRVSDDLETGVQLSWTAGSNATRFSLAAKYTPDKDSSFRAKVNNSSQIGISYQTKVRD GVNITCSSLLEGKNFNQGGHKVGFGLEFEA--------------------------QVRE QLKELTKQYDKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQIDKAK LRAGTRVALDMTTLTIMRHLPREVDPLVYNMSCEDPGDIGYAAIGGLGEQIRELREVIEL PLMNPELFMRVGITPPKGCLLYGPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIGES ARLIREMFGYARDHQPCIIFMDEIDAIRRFSEGTSADREIQRTLMELLNQMDGFDALGQV KIIMATNRPDTLDPALLRPGRLDRKIEIPLPNEQARMDILKIHAAPIAKHGEIDWEAVVK LSDDQNGADLRNVCTEAGMFAIRAERDYVIEEDFMKAVRKVQDNKKLESKLDYKPLMPDT LVSVIHRFYDEYINSTPKKLKIIDSYLAYIILTGVMQFMYCALVGTFPFNSFLSGFISCV GSFVLAVCLRMQVNPQNKTDFLGIGPERAFADFIFAHVILHLVVINFIGXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX-----ENPRNVGSLDKGDSNVGTGLVGAPACGDVMKLQIKVDDDG KIIDAKFKTFGCGSAIASSSLATEWIKGRTLTEASEIKNAHIAKELCLPPVKLHCSMLAE DAIKAALNDYKVKRQMLVLVLGDLHIPHRCNNLPGKFKKLLVPGKIQHILCTGNLCTKES FDYLKTLASDVHIVRGDFDENLHYPEQKVVTVGQFRIGLCHGHQVVPWGDTESLAMIQRQ LDVDILITGHTHKFEAFEHENKFFINPGSATGAYNPLDSTIVPSFVLLDIQQSTVVAYVY QLVVDDVKVERIEYKKMGRFIKSGKVVLILGGRYAGRKAVIVKNYDEGTQDHPFGHALVA GIDRYPRKVTKDMSKKKLKKRNKIKTFVKAYNFNHLMPTRYSVVNFDKQSVNKDAFRDPA LRWKARQDVKAKLEERYKTGKNRWFFQKLRFERTFVMMKPCGVQRGLVGEVVRRFEQRGF QLVGMKFMKASENLVHKHYEEHVQKPFFPILVQFLTSGPVVPMVWEGGVVQMARNMIGTT DGREAAVGTIRGDYGVDIGRNICHGSDAVESAQKEINLWFTKDELVTWSPVEEPMVYEGD APKPVKNGGKGQGKALKAKKAVLRGVHERRNRKKRTIVQFKRPKTLRLPRDPKYPRKSTP RRNRLDQFKIVRFPLTTESAMKKIEDNNTLVFLVDKRSNKPQIKAAVKQLYDIDVSKVNT LIRPDGEKKAYVRLAPDYDALDVANKIGIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- ------------------------------------------------------------ --------------YLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYSVVDEMFLAGEIRE TSQTKVLKQLLMLSSLEKPTIFSKIIDRSIPADIIYEDSQSLAFRDVNPVAPVHFLVIPK KIIPMFREDEQLIGHLMQVARKVAKQENGYRVVINDGKDGAQSVYHLHIHVLGGRQMKWP P-----------------------------------------VTTIPTIGFNVETVTYKN LKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSMDRDRIGISKQELVSMLE-------- ------------------------------------------------------------ ------------------------------------------------------------ -------------TFTSHTAGEHVICLHSNSTAWFGGGKLRVHLDIQVGEHANDYQQIAA KDKLTELQLRVRQLLDQVEQITKEQNYQRYREERFRQTSESTNQRVLWWSIAQTVILLIT GFWQMRHLKGFFEAKKLVMFYHVSLEHEILLHPRYFGPNLLNTVKQKLFTEVEGTCTGKY GFVIAVTTIDNIGAGYIQPSRGFVVYPVKYKAIVFRPFKGEVLDAVVTQVNKVGLFTEIG PLSCFISRHSIPADMEFDPNSNPPCYKTKDEDMVIQQDDEIRIKIVGTRVDATDIFAIGS LMDDYLGLVSRLYSKAIFSGFKRGLRNQHESIALLKIEGVFTKQETEFYWGKRCAYVYKA RNKTACPGHDKASRIRVIWGKIIRPHGNSGAVRAKFRKNLPPKAMGKRIRVMLYMAKKTY DLLFKLLLIGDSGVGKTCLLFRFSDDAFNTTFISTIG----------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------S KQKKTEEVPEGAVPAYLLDREGQTRAKVLSNMIKQKRKEKAGKWEVPLPKVRGISEAEVF KVVKTGKSRRKAWKRMVTKVTYVGEGFTRKPPKYERFIRPMGLRFKKCHVTHPELKATFC LPIIGVKKNPTSPLYTSLGVITKGTVIEVNISELGLVTQGGKVIWGKYAQVTNNPENDGC INAVLLV----------------------------------------------------- ------------------------------------------------------------ ---------------------------------PEVPLVLSDKVEEIKKTKEAVAVLRKI KAWSDIEKAKASRRFRAGKGKMRNRRRIQRRGPLVIYNQDNGITRAFRNIPGITLINVNR MNLLKIAPGGHVGRFCIWTESAFKKLDGLYGTWRKESEEKKNYNLPMPKMTNNDLTRLLR SEEIQKAIRAPKNDHKRAVLKKNPLKNWRTMMRLNPYANVQKKTAIAKAQRQAAIDKKRG ITTVDTGGKARPRKTTAGSGEQELATRTLQIQSKRFYLDVKQNRRGRFIKVAEVGAGGKK SRLLLAMSTAAEFRDHLTEFSEHYASLGPPNPENLPEDGKLKSEVMVKDNRRYYLDLKEN ARGRFLRVSPRSSQRSQIAIPAQGMIEFRDALTDLLDEFGVDDHEGPGELPEPRSMRVEN KMFYFDVGQNRRGVYMRISETNFRTAVTIPERSWARFRDIISDFVDK-ERKLRDAQMRAT INQKLVETGERERLKELLRTRLIECGWRDQLKAYCKDVVRQKGLEHITVDDLVAEITPKG RALVPDQVKKELLQRIRSFLAQQSNMNVRVAKPEDLMNMQHCNLLCLPENYQMKYYFYHG LSWPQLSYVAEDEKGKIVGYVLAKMEEDPEDSVPHGHITSLAVKRSHRRLGLAQK----- ------------------------------------------------------------ ----MSHTILLVQPGRKPEGRTYSDYESVNECLEGICKIYEEYLKRNNPNSPSITYDISQ LFDFIDSLADLSCLVFNKSTGMYIPHNKDWIKKKIYILLRKQAGKXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------------------- ----------------------GMTHIVREVDRPGSKTNKKEVVECCTILETPPMVIVGV VGYIETPKGMRTFKTLFAEHLSDECKRRFYKNWYRSKKKAFTKCARKWQDDLGKKEIEKD FGKMKKYCKVIRVIAHTQMKLLKKRQKKAHIMEIQINGGNISDKVDWARTQLEKQVPISS VFSMNEMIDCIGVTKGKGFKGVTSRWHTKKLPRKTHKGLRKVACIGAWHPSRVAYSVARA GQKGYHHRTEINKKIYRIGQGIHTKEGKVIKNNASTEYDITEKTITPLGGFPHYGEVNND FVMIKGCCMGPKKRVITLRKSLLVHTKRIALEKINLKFIDTASKFGHGRFQTHQEKQNFM GPLKKDMENIKLVVVGDGGVGKSCLLISYCTNSFPSEYVPTVFDNYSANVMVDGKPYNIG LWDTAGQEDYDRLRPLSYPQTDIFFVCFSLASRTSFENIEPKWFPEVHHFCPNVTKILVG CKEDLRGAPGGEERC-------VTYAEGAAVAKKLGMQAYCETSALTQNGVKNCFDKAL- ------------------IFDPTMKRKKKKKTPFDLDAALEDLGLDDGLAKKKKKKKKPF DFSEIDDALPKEETSLPMKKKKMDSDRDYTYDELLKRVFDIMREKNPDMVAGEKKRFVMK PPQVMRVGTKKSSFSNFAEICKMLHRQPKHLLAFLLAELGTSGSVDGNNQLIIKGRFQQK QIENVLRRYIKEYVTCHTCRSPDTILQKDTRIFFLQCEMCGSRCSVASIKSGFQAVTGKR AAIRAKTS---------------------------------------------------- ------------------------------------------------------------ ------------------------------------KHPSKPDPSGECSPELRLKGHQKE GYGLSWNPNLNGHLLSASDDHTICLWDINTTPKEGRVIDAMTIFTGHTSVVEDVSWHLLH ESLFGSVADDQKLMIWDTRSNNTSKPSHTVDAHTAEVNCLSFNPYSEFILATGSADKSV- -----------------------------------XXGTDRRLHVWDLSKIGEEQSAEDA EDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEEPDTQAS ELE--------------------------------------------------------- --------------KKKKIKREIKILENLRTGTNIITLLAIVKDPVSRTPALIFEHVNNT DFKQLYQTLTDYDIRF--------------------------------------XDWGLA EFYHPNQEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPFFHGHDNY DQLVRIAKVLGTEELYEYIDKYPIELDTKFNDILGRHSRKRWERFVHSENQHLVSPEALD FLDKLLRYDHAERLTAREAMEHPYF------QVPETLLKKRKQKEEQHREKRKIIFKRAE KYVKEYRVKERDEIRLARESRKYGNYYVP------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MQFMLLFSRQGKLRLQKWYAAHPDKXKKKITRELITTILARKPKMCSF LEWRDLKVVYKRYASLYFCCAIENEDNELLTLEIIHRYVELLDKYFGSVCELDIIFNFEK AYFMLDELLLGGEVQETSKKNVLKAIAAQDLLQEETPQGFFEDHGLGMSKAHPPELKKYM DKKLALKLNGGRTVSGILRGFDPFMNLVVDEAMEETK----------------------- ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXMAPRFEMAVGLEKGHKVTITKPKPSRRKGTQTKHAKFIRDIVR EVTGFAPYEKRAMELLRISKDKRALKFCKKRLGTHFRGKKKRE----------------- ------------------------------------------------------------ ----------LKYEFDVEFDIPVTYPTTAPEIALPELDGKTAKMYRGGKICLTDHFKPLW ARNVPKFGIAHAMALGL-------------------------FDFLDDVRRMNARQLYYQ VLNFAMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNHREEPIRVGE IVVFKVEGREIPIVHRVLKVHEKENGTVKFLTKGDNNSVDDRGLYAPGQLWLEKKDVVGR AKGFVPYVGIVTILMNDYPKFKYAVLALLGLFVLIHREMSTMNPEYDYLFKLLLIGDSGV GKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYR GAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEY ADQLGIPFLETSAKNATNVEQAFMTMAAEIKNRMGPVSAAPNVKINASTPVKQGGGGCCE DSLGEEVLRMGNEEVTSRTRLLDNEIKIMKSEVMRISHELQSQKEKIKENTEK------- -----------XXXPQDQGEEDGGNIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDPENL KPGDLVGVNKDSYLILETLPQEYDSRVKAMEVDERPTEQYGDIGGLDKQIQELIEAVVLP MTHKERFETIGIEPPKGVLLYGPPGTGKTLMARACAAQTKSTFLKLAGPQLVQMFIGDGA KLVRDAFALAKEKAPAIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFAPSND IKVIAATNRVDILDPALLRSGRLDRKIEFPCPNEEARARILQIHSRKMNVRSDVNYEELA RCTDDFNGAQCKAVCVEAGMIALRREATELTHEDYMDAILEVQAKKKANLQYYAKDAADQ NFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRQDKRVKLQIWD TAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDNAQVVLVGNKC DLEDERVVSTERGKQLADQLGLEFFETSAKENINVKAVFERLVDIICDKMSESLDSDPTQ TKRLTENPNPQNGGCQCRTTHKLAITRDYISQPRITYKTVSGVNGPLVILDDVKFPKFAE IVTLTLNDGSIRTGQVLEVSGSKAVVQVFEGTSGIDAKHTTCEFTGDILRIPVSEDMLGR IFNGSGKPVDKGPHVLAEDFLDIQGQPINPWSRIYPEEMIQTGVSAIDGMNSIARGQKIP IFSANGLPHNEIAAQICRQAGLVKLPEKSVMDDHEENFCIIFAAMGVNMETARFFKQDFE ENGSMENVCLFLNLANDPTIERIITPRIALTTAEYFAYQCEKHVLVILTDMSSYAEALRE VSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLT GYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRDDHADVSNQLYACYAIG KDVQAMKAVVGEEALTPEDLLYLEFLQKFEKNFIAQDHYENRSIYETLDIGWQLLRIFPK ELLKRIPQEKLVKYYPRDS--------------NNMLYPKEDKENRILLYACRNCDYQQE AENPCIYVNKITHEVDELTQIIADVIADPTLPRTEDHPCPSCGHKEAVFFQSQTCRSEEG MRLYYVCTLQSCAH---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------AGKVAVVGGYGDV GKGCAAALRAFGARVIVTEIDPINALQAAMEGYEVSTIEDSLKEAR-------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------NTVEEPLDLIRLSLDERIYVKMR NDRELRGRLHAYDQHLNMILGDVEETVTTMEIDEETYEEIYKSTKRNIPMLFVRGDGVIL VSPPMRTMSTSNVENLSPQIIRQVAKEISTLTRDPPEGIKVFPNEEDITDIQATIEGPAG TPYAGGVFKMKLVLGKNFPNEPPKGFFLTKIFHPNVASNGEICVNVLKKDWKTALGIKHV LLTIKCLLIVPNPESALNEEAGKLLLEQYDDYSMRAKMYTEIHARPMFKSLIDAATGSHF TSPFGLKVNETRTIAAA-DDVSCEFGSNKYFALCGFGGILSCGITHTAVVPLDLVKCRIQ VDPGKYKNIVNGFRLTVREGGMRELGKGWAPTLIGYSMQGLCKFG--------------- -----------------XXXXXDIALCPMEAVKVRIQTAPGWAKTLREGVPKLMQEEGVW GFYKGIVPLWCRQIPYTMMKFACFERTVEALYKFVVPKPRAQCSKGEQLVVTFTAGYIAG VFCAIVSHPADTIVSKLNKEKGSSFMQIGRNLGFWGMWQGLGPRIIMI------------ -------------------------HWKQERALIIGLLAAIPAGLIYPLDYAIASLTLHA HWGVTAIIMDYVHLSICTFAGLCLLTYNDIG------------XXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------- ------------------------------------------------------------ --------KVYKCDDEAVGRPQCYTSRGSAHPDSFPCDVRGSGKFKLVRHVSFVDCPGHD ILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQ AREQYEQILRFVQGTIAEGAPVVPISAQLKYNIDAVCEYVVKTIPVPVRDFTSAPRLIVI RSFDVNKPGCEVEDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKDQEGKLTCKPIFSRIV SLFAEQNDLQFAVPGGLIGVGTKIDPTLCRADRLVGHVLGAVGALPDIYIELEISYFLLR RLLGVRTEGDKKGAKVQKLSKNEILMVNIGSLSSGGRVLAVKADLAKIGLTSPVCTEIGE KIALSRRVEKHWRLIGWGQIRRGVTVKP-------------------------------- ----------------------------ENGRFVPKQSFLMRKEYFNNEETGYLTKNPMT DPTMMTDMLKGNITNVLPMIVIGGWINWAFSGFLTTKVPFPLTLRFKPMLQRGVEL---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---RPMELFMCSVLKRQGYGEGFRWLAQYINXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPA IKLQSSDGEIFEVDYEIAKQSVTIKTMLEDDEDEDDVVPLPNVNAAILKKVIQWCTYHKD DPPPPEDDENKEKRTDDISSWDAEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMI KGKTPEEIRKTFNIKNDFTPAEEEQVRKENEWCEEKXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSASAVYI LDIKGKVLICRNYRGDIDMSVIDKFMPLMMDREEDGNVAPIIQHGNTTFVYIKYNNLFLV ATSKKNSNVAMVFAFLHKIVQVFIEYFKELEEESIRDNFVMIYELLDELMDFGYPQTTDS KILQEFITQEGHKLEVAPRPPPAVTNAVSWRSEGIKYRKNEVFLDVIESVNLLVSANGNV LRSEIVGAVKMRVYLSGMPELRLGLNDKVLFESTGRGKSKSVELEDVKFHQCVRLSRFEN DRT--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------MGILDK IGDIEQEIARTQKNKATEYHLGLLKAKLAKYRGQLLEPTGKAGAKGEGFDVMKSGDARVA LIGFPSVGKSTLLNTLTATHSEACNYEFTTLTCIPGVIEYKGANIQLLDLPGIIEGAAAG KGRGRQVIAVARTADLVLMMLDATKGGKQKELLEMELESVGIRLNKQKPNIYYKIKKGGG LSMNSMVPLTHCNEKLVGMILHEYKIFNAEVLFREDCTADELIDVIVGNRVYLPCVYVYN KIDQISIEEVDRIARTPDSIVVSCNMKLNLDYLKETVWEYLALIRVYTKKRGEKPDFDDA LILRRN-CSVEHVCHAVHRTIVEAFRYALVWGTSTKYSPQRVGLNHIMHHDDVLQIIKKM AKHHPDLIFCRKQPGVAIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGSYQGRCVIC GGPGVSDAYYCKECTIMEKDRDGCPKIVNLGSAKTDLFYERKKYGFKKR----------- ------------------------------------------------IRTCHKTVEVNS IQKAADFVKAFTLGFEIGDALALIRLDDLYLESFDVTDVKPLKGDHLSRAIGRIAGKGGK TKFTMENATRTRIVLAESKIHILG------------------------------------ --RVKVAKPVVELDGDEMTRIIWEKIKEKLIFPYVDVECLYYDLGLPYRDQTNDQVTIDS AHAIQKHNVGIKCATITPDEERVEEFKLKKMWLSPNGTIRNILGGTVFREPIICKTIPRL IPGWTEAITIGRHAHGDQYRATDYVVKQKGKLEMVFTPKDGSPERMEIFDFKEGGGIGLS MYNTDESIEGFAHACFNYALKKKWPLYMSTKNTILKKYDGRFKDIFAEIF-------FDS AGIWYEHRLIDDMVAQALKSSGGFVWGCKNYDGDVQSDVVAQGYGSLGLMTSVLMCPDGK TVEAEAAHGTVTRHYREHQKGNPTSTNPIASIFAWTRGLEHRALLDGNKDLDSYCKLLEK ACVDTVDSGSMTKDLAGCIHGLKNVKPSQYLNTMDFLEAIADKFE--------------- ------------------------------------------------------------ ----------------------------HKLLGDERLKTVPIIIVANKQDVAGALSPQEV QSALGLDNINPKDHAVQ-----------------------FGDLKSDAGLSVLNDYLADK SYIEGFQPSQADSVVFKALAGPNAKFINALRWFNQIRSY--DASSLPGVAKDVNSYGPAG VAAADDDDDFDLFGSAAEKLKEERVAAYNAKKQPALIAKSSILLDVKPWDDETDMAELEK QVRSIETDGLKWGAGKLVPVGYGIRKLQIMCVVEDDKVGTDYLEEEITAFEDFVQSVDVA AFNKIKVQEVREVTRIERIGAHSHIRGLGLDDSLEARQVSQGMVGQTTARRAAGVILEMI KDGKIAGRAVLIAGHPGTGKTAIAMGMAQALGTDTPFTSIAGSEIFSLEMSKTEALTQAF RRSIGVRIKEETEIIEGEVVEIQIDRPATGTGAKVGKLTLKTTEMETVYDLGQKMIESLT KEKVQAGDIITIDKATGKITKLGRSFTRARDYDAMGPQTKFVQCPEGELQKRKEVVHTVS LHEIDVINSRTQGFLALFAGDTGEIKSEVREQINAKVAEWREEGKAEIVPGVLFIDEVHM LDIECFSFLNRALETDMAPILIMATNRGITRIRGTQYQSPHGIPIDLLDRLLIISTSPYE EKEIKQILKIRCEEEDVEMAEEALTVLTRIGIETSLRYAIQLITAANLVSRKRKGAEVSM DDIKRVYSLFLDESRSTQFLKEYQQEFMFNEMAEFDLTTRMGQYLDRHLVFPLLEFLSVK EIYDEKEMLKGKLDLLSNTNMVDFAMDVHKSLYPDQDVPTTLKEKRTEVVSELKRLQADT EPITKIFEDPEVTIHTSRDGRQLFDFLASKFAFKPEMVDTLYRFAKFQYECGNYSGAAEY LYFSRVLLPPNDKNALNALWGKLASEILMQDWDTALDDLNKLKDIIESALQSLQQRTWLI HWSLFVFFNHPKGRDLIIDMFLYQPQYLNAIQTMCPHILRYLTTAVITNKTVLKDLVKVI QQESYTYRDPITEFLECLYVNFDFDGAQQKLRECETVLVNDFFLVACLDDFIENARLFIF ETFCRIHQCISINMLAEKLNMPPDDAERWIVNLIRNARLDAKIDSKLGHVVMG------- ------------------------------GVEIETTKPGDGATYPKQGQTAVVHYTGTL QDGKKFDSSRDRGKPFEFKVGASQVIRGWDEGVAQMSVGQRANLTCTPDFAYGSRGFPGA IPPNATLIFDVELLAIKMPKYYCDYCDTYLTHDSPSVRKTHCNGRKHKENVRLYYQKWLE EQVQKLVDDTTAAFKAGKIQSNPFSGGGAMIPPPASL----AGP-MPMLGPGPGGPMPPM RPPHMPMGPHMPMMGPMEPLTLERDVQRAVELLESLQRSGDASKMAALQKVLQSDFCRAV REVYEHVYETVDITGSPEIRANATAKATVAAFAASEGHAHPRVVELPKTDEGLGFNVMGG KEQNSPIYISRIIPNGVACRHGGLKRGDQLLSVNGVSVEGEPHEKAVDLLKAAQGTVKLV VRYTPRVLEEMEARFDKQRSARRRQLACLIGVALSEPVVHFKEDFWEDRWVESTHKTSDA GKFVLTAGKFYGDAEKDKGIQTSQDAKFYALSAKFDKGFSNEGKTVVVQFTVKHEQNIDC GGGYAKVFSSDLDQKDMHGESPYLMMFGPDICGPGTKKVHVIFNYKGKNLLTKKDIRCKD DVFTHLYTLIVRPDNTYEVKIDNAKVESGDLETDWDFLPAKKIQDPNAKKPDDWDEKEKI DDPEDKKPEDWEKPEHIPDPDAKKPDDWDDEMDGEWEPPMIDNPDYKGEWKPRQKDNPNY KGKWVHPEIDNPEYTTDASLYKFTDIGAIGFDLWQVKAGTIFDNVLITDDEKHAEAVGEE TWGKTKDAEKKMKDAQDDDERKVREEEEKKKKDEEDAKGGEEEE---------------- ------GNRLVAKYYDDQFPTVKEQKNLFNKTHRANAEIIMFEGLTCVYRSNVDLFFYII GSAQENELILASVLNCLYDATSQMLRKNVEKKALLDNLDGVYLAIDEICDEGIILESDPT AVSQKVAIRSDDIPLGEQTVAQVIQSAKEQIKWSLLKMNIFRLIGDLSHLLAIFVLLVKI WKTRSCAGISGKSQIMFGLVYLTRYLDLFTAFISLYNTTMKVIFISASCATIYLVFVKFR ATYDSNHDSFRMEFLIVPVGGLAFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGE AETITSHYLFALGSYRGLYILNWVYRYYFEGFFDLIAVVAGVVQTILYCDFFYLYVTKVW KGKKLTLPAMKIEEVKSTTKTQRIATHSHVKGLGLDDNGFALQTAAGLVGQELAREAAGL IVELIKSKKMAGRAVLLAGPPGTGKTAIALAIAQELGSKVPFCPMVGSEVYSTEIKKTEV LMENFRRAIGLRIKETKEVYEGEVTELSPVETENPMGGYGKTVSHVVIGLKTAKGTKQLK LDPSIYESLQKEKVEVGDVIYIEANSGAVKRQGRSDTFATEFDLEAEEYVPLPKGDVHKK KKVIQDVTLHDLDVANARPQGGQDILSMMGQLMKPKKTEITDKLRKEINKVVNKYIDQGI AELVPGVLFIDEVHMLDIECFTYLHRALESSISPIVIFATNRGKCTIKGT-DLSSPHGIP LDLLDRLMIIRTLPYSQEEMVQIINIRAQTENIPVAEESLHLLGSIGVKTTLRYAVQLLT PSNLLARINGKDTIMREDIEEINDLFYDAKASAKILAAQEDKFMK--------------- ------------------------------PQRSVEGWILFVTSVHEEAQEDDIIDKFGE YGEIKNIHLNLDRRTGFLKGYTLVEYETFNEAQTAMESLNGTEILGQKINVDWSFVRGPQ K---SYQLYRNTTLGHTLQESLDELIQCGQITPQLALKVLLQFDKAINSALATRV----- ------------------------------------------------------------ ----LDAHLKQDPNAKLACETCSKTGMVMLLGETRSKAKVDHQSVVREAIKSIGY----- ---------------------------------XXXXXXXMFGYATDETEECMPLTIMLA HKLNAKMAELRRNGGLPWARPDSKTQVTCEYRSDEGAMIPLRIHTIVISVQHSDTVTTEQ LRRDLMEKVIKPVVPEQYLDAETIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAH GGGAFSGKDSSKMDRSASYALRWVAKSLVKAGLCRRALVQVAYAIGIAQPMSVFLTTFGT GVKSDQELREIVRNNFDFRPGMIVKELRLRAPIYQKTACYGHFGRPEFTWEQPKKLVFMA GSALKRLMAEYKQLTLNPPEGIVAGPVDEENFFEWEALITGPEETCFGGGVFSTRLTFPA DYPLSPPKMKFTCDIFHPNIYQDGRVCISILHAPGDDPMGYESSAERWSPVQSVEKILLS VVSMLAEPNDESAANVDAAKTWREDRHKFEEIANRAVRKSLGLXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMATYKVVMIRHGESQWNKENRFCGWFDADLSELGIEEAKNGGKMLKEKGYTFDVAHT SVLQRAIKTLYHVQDQMELHWIPVHRHWRLNERMYGALQGLNKSETAAKHGEEQVKIWRR SYDTPPPVVDEASEYFPGKDPKYKFVDHMLIPRSECLKDTVARALPYWYDVIVPDILNGK KVLIAAHGNSLRALVKYLDNMTDAEIMGLNIPTGIPLVYELDAHLKPIKHYYLADEAAVK AAM-----------------------------NKVSRQSVLCGSQNIVLNGKTIIMSDCI IRGDLANVRIGRHCIISKRAVIRPPFKKFSKGVAFFPLHVGDHVMIEEDS------VGSY VHIGKNCVIGRRCVLKDCCAIADNTVLPPETVVPPFTIFSGSPG---------------- ---------YDLMKHAAATLGSGNLRLAVQLPDGEDLNEWVAVNTVDFFNQINMLYGTVT EFCTEQSCPVMSAGPKYEYHWADGHTVKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKI GVPFPKK-------------KKXXXXXXXHFDQVVQLEEEAHLNTSFKHFVFFVQEFQLV DRRELAPLSELIEKLTSKD----------------------------------------- ----------FMSKNNRPPLSLARIVRNMKDKSRDGKTVVCVGTITDDLRVLEIPKLRVC ALHVTERARARILKAGGEIMTFDQLALKSPTGQNTLLIQGPRKSREAYRHFGRAPGVPHS NTKPYVRSKGRKFERARGRRKSRGYK---------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---VFDYVPPELVTLYISNIGGHAPSYVYRLLSELYHMIIPIRCFTCGKVIGNKWEAYIG LLQAEYTEGDALDALGLKRYCCRRMLLSHVDLIEKLLNYAPLEKKSPEAVEGRKHIDVQT ELYLEELSDRVEEADVECQTDAFLDRPPSPLFIAAKTGVDIATQILEGDLFDFNCEVKPI LEVLVGKTVEQSLLEVMEEEELANLRSQQRAFEELRNAELVEQQRLEEQERRHREEKERR MKQQREILRKQKETADKISARAFAQSYLADLVPSVFGTLSDNGYFFDPVERDVEQSFMPW LMERVEEQLVKVVRGRTVMDGILRDVVKARIEAYNQ----------------------RV PKLYAMRLFAPDQPTAKSRFWYHSSMLKKMKKEXXITAGVTQINERKPLQIKNFGIWLRY VSRSGIHNMYREYRDLTTASAVTQCYRDMGARHRARASSIQIIKVEVVPSAKTRRAAIKQ FHNPSIRFPLPHRVS-----------------TAVEEMNIYWQKNENRPQSPWLVYRLEF QSALSATHRATGFGMTIALWAI---------------------------------FIVWP FFYHALNGCRHLTWDAGKAFELETVYKTGYVV-----------------------SRTDQ ERALLDSTTLYVGNLSYYTTEEQIYELFSRCGDVKRIIMGLDKFKKTPCGFCFAEYYTRP DTENGMRYVNGTRLDDRIIRTDYDAGFKEGRQYGRGKSGGQVRDEYRTDYDSGRGGYGKL MQ---KPNYTLKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTINGH KLGISDVAWSTDSRLLCSASDDKTLKIWELATGKCLKTLKGHSNYVFCCNFNPQSNLIVS GSFDESVRTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKKEKYCIFANFSVTGG KWIVSGSEDNMVYIWNLQTKEIVQKLAGHTDVVLCCACHPSDNIIASAALENDKTIKLWR SDVMLIYKDALSQDEVLTDAYKGILLKVEGKDDALIGGNASTGINIVLADKKAFMNFMKG YMKKIKAWAFYVGLIPCKWETPVFYYFKHGLISEK-MAVEFDGGVVIGADSRTTTGSYVA NRVTDKLTEVTDFIYCCRSGSAADTQAITDIVKYHLNFHKME------------------ -------XXSIICAGWDKRLGGQVYTVPLGGMCQRQPFSIGGSGSTYVYGHVDANFKEGM TKEECLDFTAKTLALAMMRDGSSGG----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------TLNPVFNETFTFKVPYAEIGAKTLVFAIYDFDRFSKHDQIGQVHMPLNSVD LGRVVEEWRDVMKAEADSEKENKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSD ------------------------------------------------------------ --PIGRVVLGCNSTGTELRHWSDMLANPRRPIAQWHTLQELPEKNMVLADLKRKSTTALR SLSSATVINEEVLNAMLKDICKALLEADVNVKLVKKLRENVRAVIDFDEMAAGLNKRRMI QSAVYKELVKLIDPGVKAWSPTKGKNNILMFVGLQGSGKTTTCTKLAYHYQKKGWKACLV CADTFRAGAFDQLKQNATKARIPFYGFMTKGNEQESMARLKKLMTIMDS----------- ----------------------NDSELDSHE--GARRFTRGRVQRVARGSGVSVREVQEV LTQKFAQMVKRMGGIKGLFK-GGDMAKNVQAQMSKLNSQMAKMMDPRTLQHMGGMAGLQN MMRQFQQGAMSIMSYNGGSVMAMKGKNCVAIASDLRYGVQAQTVNMNFPKVFEMGPTLYM GLAGLATDVQTVSQRLKFRLNLYELRENRNIKPKTFMMMVSNLLYERRFGPYFVEPIITG LDPKTNEPFLASLDLIGCPMIPEDFVVVGTSAEQMYGMCESLWEPDLEPDDLFETISQAL LNSVDRDALSGWGAEVHIIEKDKVTVKRLKARMDMTSKDYYFDSYAHFGIHEEMLKDEVR TLTYRNAMYHNKHLFRGKTVLDVGCGTGILCMFAAKAGAKKVIGIDCSSIIDHAQKIVKS NGLDDVITLVKGKAEEVTLP--VEKVDIIVSEWMGYCLFYESMLKTVLFCRDKWLAPGGL IFPDRATLYICGIEDRQYKDEKINWWDTVYGFDMSCIRKVAICEPLVDVVDPNQVVTNSC LIKEVDMYTIQESDLTFSSPFHLQCKRNDYIQALVTFFNIEFTKC-KRTGFSTGPESKYT HWKQTDECLSVKRGEEVYGVVNIKPNMKNNRDLDFTIDIDFRGELSEMVESNHYKMR--- ----------------------------------------------LMGKNTMIRKAIRG HLENNPNLEKLLPHVKGNIGLVFTKNELVDVRDKILNNKVAAPAKAGAIAPLPVVLPAQN TGLGPEKTSFFQALAIPTKITKGTIEILNDVNLIKEGDKVGASEATLLNMLKISPFTYGL MIQQVYDSGTVFSPEILDITDDDIRGRFMQGVANIASVSLAIGYPTIASAPHSLVNGFKN LLAVAAATDINFKEAETMKE---------------------------------------- --TSVGEIEEAFTTFVKRDDIAIVLVNQNIAEMIRHVIDAYQEPIPAVLEIPSKDHPYDA SKDSILRRAKGMFNPEDFRGNEASLPMELCSTFDADEIQRLGKRFRKLDLDNSGSLSVDE FMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEAKLRFAFKIYDMD KDGYISNGELFQVLKMMVGSNLKDAQLQQIVDKTIILADTDGDGKISFEEFCAVVGNMDV HKKMVVDVMTYITSWDEFAKAAERLYLADPMKSRFVIKYRHKDGQLLIKMTDDIVCLQYR TEHAQDVKKLEKLTSQLMRHMGSKDLYEEVKLYRTGREREKYDNLADLYAVINTLQCLEK AYIKDSVTPKEYTAACSKLLVQYKAAFKQVQGDEYPTVEVFTQKCKLDCPIALERIKEDR PITIKDDKGNTSKCIADIVSLFITIMDKLRLEIRAMDEIHPDVRDLMETMNRL------- -----------------------------------------------MLSSMVKEHQARQ QSRKEVQEKRKXEAAGATALTHALVDHLNAGVAQAYVNQKKLDTETKILQANASHFARQT MQWLKLVEDFNQSLKEIGDVENWARSIETDMRTISSALEYAYK----------------- ------------------KLKSAFSQHKRSIRASITPGTVLILLAGRQKGKRVVFLKQLG SGLLLVSGPYLLNGCPLRRISQNYVIATKTKLDISGVKLPERLNDEYFKRVQLKKPKHQE GEIFDTKKEDYAVTDVRKEDQVAVDKQLLSVIRANPEKKYLQGYLGAMFSLTNKQYPHKM IF---------------------------------------EKKTIAEIKKMAKAGQMDA VKIMAKDLVRTRQYVKKFMIMKANIQAVSLKIQTLKSTDDMARAMKGVTKAMKNMNNQLK LPQIQKIMQDFEK----------------------------------------------- ------------------------------------KKCDYCLLTAASNRN-GDPEELLV CKDCQAKAHPSCMKYSEELAKRARTSPWQCIDCKTCYVCDDSGDPDAMLFCDACDKGYHM NCHNPPIQDKPTGKWECSTCILEL--TLDRVVNLYPLTNYTFGTKEALYEKDSSVAARFK RMRDEFGRIGMRRSVEGVLIVHEHGLPHVLLLQLGTTFFRLPGGELNPGEDQVEGLKRLL TETLGRQDGAAMDWLIEDTIGNWWRPNFEPPQYPYIPAHITKPKEHKRLFLCQLPEKALF AVPRNYKLVAAPLFELYDNAAGYGPIISSLPQALSRFNFIYN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------LELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVC TTVAIAIVAETCSPFTVLPGLMNEYRVPELNVQNGVLKSLSFMFEYIGEMGKDYIYAVTP LLEDALMDRDLVHRQTAMASIQHIALGVYGFGCEDALNHLLNHVWPNIFETSPHVVQAFM GAVEGMRVGLGSCRVLQYTLQ--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------EGEYEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGIN PFDSQEAKPYKNDPEILAMTNLVSSYQNNDINEFETILKTNRRNIMEDLFIREHIEDLLR NIRTQVLIKLIKPYTRIHIPFISKELNIDVSEVESLLVSCILDNTIHGRIDQVNQVLELD SGVAQYSALDKWTTQLQSLHQSIVNKMA-------------------------------- ------------------------------------------------------------ ---------------------------------DQRELIFRQREEDLKRLSKPLATSIWD ETLYKAWSSIVYLLIPNVQQLETNLGNFGNIIDADEVLLFERATFLVISHCQRKPHQDVH RFEKISNIIKQFKLGCSKLAASFQSMEVRNSSFAAFIDIFTSNTYVMVVMSDPTIPSAAT LINIKNARKHFEKLERVEQVLSFSTRLFSVLRFESVIHEFDPYFNYRTTRFLTENGFYNF HNWFDDRAWYPLGRIIGGTIYPGLMITSAAFYHTLNFLNITIDIRNVCVFLAPAFSSLTT IITFILTKELKDAGAGLVAAAMIAIVPGYISRSVAGSYDNEGIAIFCMLLTYAMWIKAVK TGSVFWGSMCALSYFYMVSSWGGYVFLINLIPLHVLALMLTGRFSHRIYVAYNSVYCLGT ILSMQISFVGFQPVQSSEHMAALGVFGLCQIHAFIDYVRSKLSREQFELLFRSLALVSAV VIGTATGKISPWTGRFYSLLDPSYAKNNIPIIASVSEHQPTTWSSFYFDLQMLVFLFPAG LYFCFKKITDANIFIIMYGVTSIYFAGVMVRLMLVLAPVMCILSGIAVSATLSSYMKNLD ISKKADTTYPIKNEVATGVILLVTAFLITYTFHCTWVTSEAYSSPSIVLSARAGDGGRII FDDFREAYYWLRHNTPEDAKVMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMAS TEDKAYEIMRELDVDYVLVIFGGLTGYSSDDINKFLWMVRIGGSTDRGAHIKETDYYTPQ GEFRIDKEGAPTLLNCLMYKMCYYRFGSVYTEGGKPTGYDRVRNAEIGNKDFELDI---- ---------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQETFLLFDNKGDGKI AADQLGEVLRAVGQNPTEAEVRKSNNPEARVNFETFLPILANVNKNKDTSPVDEFVEGFR VFDKDQNGTINLAELRHLLTTLGERLSDEEAEMLLQGQEDAQGNVNYEEFVKMVLSG--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ITINSFGTELTKDDRAKLYPRCGK LHPDGLASLARADDYEQVKAVAEYYAEYRALFEGAGTNPGEKTLEDKFFEHEVLLMKNAF MQQFQFGIFYSYVKLKEQENRNIIWIAECVAQRHRAKIDSYIPIF--------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------KYLASGGNDNLLNIWSPEAGGALYTLTQHQAA VKALAWCPWQPSVLASGGGTADRMIRFWNCNTGACLNAVDTKSQVCSILWSKDYKELISS HGFAQNQLIIWKYPTMTKVAEMTGHTARVLHMAMSPDG---------------------- -------------------IVGLYYLLTGQGFRFDIGWFLEETSPYMWANMGIGLAISLS VVGAAWGIYTTGCTILGAGVKAPRIKTKNLVSIIFCEAVAIYG----------------- ------------------------------------------------------------ -----------MAASNRLKKELLDAIDDSNMLVWKALIMPDKAPYDKGAFKIQIVYPPEY PFKPPKITFMTKIYHPNIDEKGQVCLPIISAENWKPATKTEQVINSLVELISSPEPEHPL RADVAEEYTRDRKKFNKKAEEFVQKFGEKRP------THPQQCSSLRKNGFVCIKGRACK IVDMTTSKTGKHGHAKVHLVGLDVFTGKKYEDLCPSTHNMNVPEIKRLELQVINIDQGFL SLMTDSGELRSDLKVQAEVLKAMGDECVTKLKTSK------------------------- --------------------------------------VSDFHNHCVKVFDEGTFKFSFG SNGEGNGQFNAPTGVAVDKLGNILVADWGNSRLRPGDSQGSFLSYINLYGPQGLGVTSDG HVVVADSGNHCIKIYKYLMAAGPIAERNQDATVYVGGLDEKVSEAILWELFLQAGPVVNV HMPKDRITQSHQGYGFVEFMGEDDADYAIKIMNMIKLYGKPIRVNKASAHQKNLDVGANI FIGNLDPEVDEK------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------KVEAKKTVNPLFEKRPRNFGIGQDIQPKRDLSRFVLWPKY IRLQRQKAILYQRLKVPPAINQFTQALDRQTATQLFRLMDKYRPETKQGKKARLTSRAEE RVKGKDDVPTKRPLMVRSGVNTVTTLIEQKKAQL-------------------------- ------------------------------------------------------------ -------------------MRYVAAYMLAVLGGNSAPTEKDLKQILSSVGIDAEAENLKK VIAELAGKDLGAVIAEGREK---------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------EGGFAPNILDNFEGLELLKEAIAKAGYTDQIKIGMDVAASEFC KLYDLDFKNPNSDKSKWLTSDKLYEVYAEFIKRYPVVSIEDAYDQDDWAAWSKMATIQLV GDDLTVTNPKRVQRGIDEKACNCLLLKVNQIGSVTESIEACNMSRKAGWGVMVSHRSGET EDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQIMRIEEELGADAIYAGVHFRDPGAPPA AGAFRQRDTGPTSFRKFYERGDFPIALEHDTKGNKIAWKVEIEKLDYHHYLPLFFDGLCE TQHPYEFFARQGVHDMLEHGGGKILPVIPQLIIPIKNSLSTRNPCVMCTTLKILQHLVTA ADMVGEALVPYYRQILPVLNIFKNKNLNSGDGIDYRQQKRENIGDLIQETLEGFERTGGG DAFINIKYMVPTYESCMMNAPPTFESFLLFEGEKKINILKDTKVPNAALFTVNKEDHTLG NMINSQLLKDPQVLFAGYKVPHPLEHKFVVRIQTTPDYSPQEAFTNAITDLISEISLLEE RFAQAVKEKQE------------------------------------------------- ------------PSARNSAYYCELCDVGLNTEVDWRNHMQGNQHQKKMAEMVGPEESNPP PVKKK------------------------------------------------------- --------------MGCTMSAEERSALERSKQIEKNLKEDGIQAAKDIKLLLLGAGESGK STIVKQMKIIHEGGFTTEDNKQFKPVVYSNTIQSLVAIIRAMGTLNIAFGDNERESDAKM VLDVIARMEDTEPFSEELLHAMRGLWVDTGVQECFGRSNEYQLNDSAKYFLDDLERLGLS DYMPTEQDILRTRVKTTGIVEVHFLFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCV AMSEYDQVLHEDETTNRMQESLKLFDSICNNKWFTDTSEEKIKKSPLTIAFPEYTGKQTY EDAAAYIQAQFEAKNKSTTKEIYCHQTCATDTNNIQFVFDAVTDVIIANNLRGCGLYYHS QFLNPPQLVGNFALLPLKSQFKGPAFDIVDESLMYFKANVFFRNYEIKSEADRTLIYLTL YITECLKKLQKCQSRNAGLKEMHTLAISTYYIPGDARFPLNAMYLKPKNRQEEDTMRSYI LQLRQECGVRLCDKVFDPSTDKPSKWWMCFAKRKFMDKSLSAPGQAGPYNYSYIFKYIII GDMGVGKSCLLHQFTKKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVT RSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIFLIGNKSDLEAQRDVTYE EAKQFA------------------------------------------------------ -----------------MVVKAVCVLQTEGVSGTVHFQQDAAVTVSGDIKGLAAGKHGFH VHEFGDNTNGCTSA------------------------------KVEITDKQLSLTGEHS IVGRTIVVHKDEDDLGKGGHDDSLTTGHAGARLACGVIGISKMVNFTVDEIRGIMDKKHN IRNMSVIAHVDHGKSTLTDSLVSKAGIIAGARAGDARFTDTRKDEQDRCITIKSTAISLY YELPKEDLSNAFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQA IAERIRPVLFMNKMDLALLTLQLEAEDMYQTFCRIVESVNVIIATYCQEDSPMGDIQVDP AKGTVGFGSGLHGWAFTLKQFAEKYAAKFSIEVPRMMKRLWGDQFYNCMRGFTQYILTPI YMVFNTLMPKEEALALIEKMGIKLTVDEKDLMDKKLLKTAMRKWLPAGDALLQMIAIHLP SPVTAQKYRMHLLYEGPMDDEVGLAILSCNPKGPLCMYISKMVPTTDKGRFYAFGRIFSG TVSTGLKVRIMGPNFVPIKNVQRTILMMGRYVEPIEDVPCGNICGLVGVDQYLVKTGTIT TFEHAHNLKVMKFSVSPVVRVAVECKNPSDLPKLVEGLKRLAKSDPMVQCSIEESGEHVI AGAGELHLEICLKDLEEDHAQIPIKVSDPVVSYRETVSEHSDRTCLAKSPNKHNRLFMRA QPMPEGLAEDIDKGDVSPKGELKERARYLAEKYDYDVTEVRKIWCFGPEGTGPNIVVDCT KGVQYLNEIKDSVVAGFQWASKEGVLCEENMRGVRFDIHDVTLHADAIHRGGGQIIPTTR RVLYACCLTAEPRMLEPVYLVEIQCPEAAVGGIYGVLNRRRGHVFEEYQTPGTPMFVVKA YLPVNESFGFTADLRSNTGGQAFPQCIFDHWQQFVVADCRKRKGLKEGVPALDNYLDKMX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- ------------------------------------------------------------ ----------------------------LVVGTAGRRVLVWDLRNMGYVQQRRESSLKYQ TRSIRCFPNKQGYVLSSIEGRVAVEYLDPSPEVQKKKYAFKCHRVKEDGIEKIFPVNAIA FHSMHNTFATGGSDGFVNIWDGFHKKRLCQFHRYPTSIAGLAF----------------- --------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXMDDDAETYKLWRIRKTIMQLSHDRGYLVTQDELDQSLDQFKEQFGDKP SERRPGRSDLIVLVAHNDDPTDQMFVFFPEEPKVGIKTIKTYCQRMQEENISRAVIVVQA GMTPSAKQSLTDMAPKYILEQFLESELLVNITEHQLVPEHVLMTPEEKKELLERYKLKES QLPRIQQGDPVARYFGLKRGQVVKIIRPSETAGRYITYRLVV-KKDSIGTVIGIDLGTTY SCVGVFKNGRVEIIANDQGNRITPSYVAFTSEGERLIGDAAKNQLTTNPENTVFDAKRLI GRAWSEKTVQHDIKHFPFKVINKNDKPHIEVNVGSETKLFAPEEISAMVLSKMKEIAEAY LGKKIVNAVVTVPAYFNDAQRQATKDAGVIAGLNVMRIINEPTAAAIAYGLDKKEGEKNI LVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRK SNRAVQKLRREVEKAKRALSAQHQTRIEIESFYEGEDFSETLTRARFEELNMDLFRSTMK PVTKVMEDGDLQKTDINEIVLVGGSTRIPKVQQLVKDLFGGKEPSRGINPDEAVAYGAAV QAGVLSGEEDTGDLVLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPT VTIQVFEGERPMTKDNHVLGKFDLTGIPSAPRGVPQIEVTFEIDVNGILKVSAEDKGTGN KEKIVINNDNNRLNPEDIERMINDAEKFAEDDKAIKEKVEARNELESYAYSLKNQMNDKE KLGAKLSADDKAELEKAVNKEISWLEKNQNAEAEDFKTHKKDLEGIAQPIVNRATGGKPE GGADSEKDELDEGVEDPELEAIKQRVREMEEEAEKLKEMQTEVEKQMSMEDKIEVDNRSM YVGNVDYGATAEELEAHFHGCGSINRVTILCDKFTGHPKGFAYVEFADKDSISTAQALDD SLFRGRQIKVNPKRTNRPGISSTDRAPRGRGYRGRGGGGYYGYSPRPR--GRFRPRRSAW YSPYVLFETLQELAQRGGFQTLVDAVRAEKDKKARLQETILKEEEGRKRVKTLQRQLQDV KKDQEVEIQQRNEMIAHLKDQLQEMKAKTNMEGKYIKKCAEVGVSQTQKRCAMAEREMRD EIEILREKIDEETRVNAEIESYLRTHQEILGQKVDYWMEKYDKDVEAKQHELDVLKASKA KDLERLQELTKLYAEYEQVVVEDRIEKEKARRKAEQEMEELKAAVRLQSWFRGVMVRKGL GPYSKKEK---KVGINGFGRIGRLVMRSCLAAVKVVGVNDPFIDLDYMVYMFKYDTTHGR YKGTVELVIDGHSVEVFQKMKADEIPWDSCGATYLVESTGVFTKKEKAGMHLKNGVKHIV ISAPSADAPMYVMGVNHEKFNKEDRILSNASCTTNCLAPLAKVINDNFGIVEALMTTIHA YTATQKVVDGPSSKAWRDGRTAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPVQDV SVVDLTARLKTGASMDAIKAAVKGPMKGFLAYTEDMVVSSDFIGDTHSSIFDSKAGISLN DNFVKLISWYDNENGYSSRVVDLLKY---------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------FSSVFPGPEIMSK LAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQ RSHVIIMAATNRPNSVDTALRRFGRFDREVDIGIPDATGRLEILRIHTKNMKLSDDVDLE QIAAETHGHVGADVAALCSEAALQQIREKMDLIDLEDESIDAEVLDSLAVTQENFRWALS KSNPSALRETAVEVPNVSWEDIGGLENVKRELQELVQYPVEHPEQFLKFGMTPSKGVLFY GPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFD ELDSIAKARGGNAGDGGGAADRVINQLLTEMDGMSSKKNVFIIGATNRPDIIDPAILRPG RLDQLIYIPLPDEKSRIQILKANLRKSPVAKDVDLDFLAKMAHGFSGADLTEICQRGCKL AIRQSIEHEITKERERAANPDDYDPVPEITRVHFEEAMKFARRSVTDNDIRKYEMFAQTL QQSRGFGS---------------------------------------------------- ------------------------------------------------------------ ----------------KAPSYSCLMTTSWDKTVKFWDTRTPNPMLTIQLPERAYCADVLY PMAVVGTAGRGLIIYQLENQPQEFKRIESPLKYQHRSVQIFTDKKSNSPVGFALGSIEGR VAIHYVNPSNPKDNFTFKCHRGGVQDIYAVNGIAFHPVHGTLATTGSDGRFSFWDKDART KLKTSEQMDQPISTCCFNAQGNIFAYSSSYDWSKGHEGFDPQKMKPHVFLRSCYDEVKPS SKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMDE PEVLTTLKLLIIGESGVGKSSLLLRFTDDTFDPEQSATIGVDFKVKTLTVDGNRAKLAIW DTAGQERFRTLTPSYYRGAQGVILVYDVTSKSSFNKLDAWLNELETFATKHEII------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------RNFEKALQQIDDSLIYWPRYLKHKCKQRLIKITQYLIRI RKLTLKRQKKIVPLNQKVERREKRREEKALVAAQLNTAIEKELMDRLKAGTYGDIYNFPS HAFDKALEEEEVS--------------------------XXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDIRPN HSIYIGNLNEKIKKDELKKSLYAIFSQFGQILDIVALKTLKMRGQAFVIFKDINSATNAL RSMQGFPFYDKPMRIQYSKKDSDMIAKIKGTFVERPKRKKAPEPKRKRKQAAPTTIPEQP PNQILFLTNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENEIQSAAAKDALQ GFKITPTNAMKISFAKKMDSQGRKVIVCDNGTGFVKTGYAGTNFPEHIFPSLVGRPLLRS TAKIGDIEIKDLMVGDEASQLRSMLEVTYPMENGVVRSWEDMIHLYDYTFGAQKLNINPR ECKLLLTEPPLNPTKNRQKMVEVMFEHYQFDGLYVAIQAVLTLYAQGLLTGVVVDSGDGV THICPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMMKEKLCYV GYDIEQEQKLSLETTVLVESYTLPDGRVIRVGGERFEAPEALFQPHLINVEGFGVAELLF NTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLEREIKQLYLERVLKGDTTKLSKFKIR IEDPPRRKHMVFLGGAVLADIMKDKDSFWMTRAEYEEKGLRCLEKLGVSMSETAGKPIQC KAAIAWEAKKPLSIETIEVGPPKAGEVRLKVLATGVCHTDAYTLDGFDPEGKFPCVLGHE GGGIVESVGEGVTSVKAGDHVIPLYVPQCRECKFCKSPKTNLCQKVR------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------HKGWGESVIVGVAPAGHEISTRPFQL VTGRVWKGTAFGGWKSRQSVPKLVEDYASGKLLVDEFVITAGGMDKINEAFDLMHEGKS- --------------SGSGVIKAGFAGDQVPKYHFPNFIGRPKHVRVMAGALEGDTFLGPK AEEHRGLLTIKYPMEHGVVRDWNDMERIWQYIYSKDQLQTFAEEHPVLLTEAPLNPRRNR EKAAEIFFETFNVPALFISMQAVLSLYATGRTTGVVLDAGDGVTHAVPIYEGFAMPHSIM RVDVAGRDVTRYLQLLLRKEGHNFHTSAEMEIVRTIKERACYLSINPQKEETMETEKSQY TLPDGSVLEIGPARFRAPELLFRPDLIGEECEGIHEVLAFAIQKSDMDLRRVLFSNIVLS GGSTLFKGFGDRLLSEVKKLAPKDIKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKR EYDEEGVRAVHRKTF---KIEKVVVHPLVLLSVVDHFNRMGKVGNVKRVCGVLLGANKKG ELDVSN-----------------------------------XEKVVGWYHTGPKLQQNDI ATNELMRRYCPNSVLVIIDAKPKDLGLPTEAYIAVEEVHDDGSPTSKTFEHIPSEIGAEE AEEVGVEHLLRDIKDTTVGTLSQRITNQLMGLKGLNSQIEDIHNYLEKVVQGKLPINHQI VYHLQDVFNLLPDVNLMEFVKAIYVKTNDQMLVVYVASLIRSIIALHNLINNKIQNRDAE KNEGKEKKMGLLFTRLWSLFTNEEHKVIIVGLDNAGKTTILYQFLMNEVVHTSPTIGSNV EEVVWKNIHFLMWDIGGQESLRSAWNTYYTNTEFVILVVDSTDRERLTITKKELYKMLAC EDLKKAAVLIFANKQDIKG----------------------------------------- ------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXPPPGKRKEIYKYEAPWTLYSMNWSVRPDRRFRLAVGSFVEEYNN KVQIVSLEEETSEFTSRSTFDHPYPTTKIMWIPDTKGVFPDLLATSGDYLRVWRATRLEC LLNNNKNSDFCAPLTSFDWNEVDPNLLGTSSIDTTCTIWGLETGQVLGLVAGHVKTQLIA HDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLAWNKQ DPNYLATMAMDAMEVIILD----------------------------------------- ---------------LAYTASGEINQIQWSSTQPDWMAICYNNCLEILRV---------- ------------------------------------------------------------ -----------------------------------------------------NPVNSTV PIASEVFKKRGVYDPKKIFGVTTLDIVRSNTFVAQAKGLDVNKVNIPVIGGHSGVTIIPL ISQGTPPVSFPQDERDKLTHRIQNAGTEVVEAKAGAGSATLSMAFAGARFVNSVLEALNG EEGVVECAFVRSDETEAKYFSTPLLLGKNGVEKNLGLGKLLEFEVNLIQKAMPELKANIA KGEEFISNN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------TPDDLQDKGVAYCSTYSHCEVHPAMILGVCASIIPFPDHN QSPRNTYQSAMGKQAMGVYITNFHVRMDTLANVLFYPQKPLVTTRSMEYLRFRELPAGIN SIVAIASYTGYNQEDSVIINESAVDRGFFRSVFFRAYKDAESKKGLDQEEIFEKPNREHV QGMRHAVYDKLDEDGIIAPGTRVSGDDVLIGKTLTLPESEDELEGKVQQYSKRDTSVFMR RSETGIVDQVMVTINQEGYKFCKVRVRTTKTPQIGDKFASRHGEKGTCGIRYRQEDMPFT CEGLTPDIIINPHAVPSRMTIGHLIECLKGKVSANKGEIGDATPFNDTVNVQKISQLLYE YDYQLRGNEV-------------------------------------------------- -----------MERDCQIAHGAAQFLRERLFEVSDPYRVHVCNICGMIAIANLRNNTFEC RGCKNKTQISQVRLPYACKLLWQELMCMNIAPRMM-LTQEAPGGFSFENCRRNALLEKGF KPPKVYKTGTTIVGIVYKDGIVLGADTRATEDTIVADKNCSKIHYIAPNIYCCGAGTAAD TEMTTCMISSQIELHRLNTGRVPRVCTALRLLKQMLFRYQGHISA--------------- ------------------------------------------------------------ -----------------------------------------------------TKVTFKI TLTSDPKLPYKVLSVPEQTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPAQSAGNVFL KHGSELRLIPRDRVGH--FTFAAFAYIVALILCAFLIFFIIYHIIAFDELKTDYKNPIDQ CNSLNPLVLPEYGLHIFFNILFLLSWQWGTLLMNAPLIAYHINRYLHRPVMS--GLYDPT SIMNADQLNRAQREGWVKLAFYLLSFFYYLYSMIYVLVSSMGLLTILKKMKQKEKEIRLL MLGLDNAGKTTILKKFNGEDIDTISPTLGFNIKTLEHRGFKLNVWDVGGQKSLRSYWRNY FESTDGLIWVVDSADRRRLQDCRQELDALLLEERLSGATLLVFSNKQDLPGALGPEEIKE AMELDNIKTHHWLIKGCSAVTGENLLTGIDWIIDDIASRIFTMD---------------- ------------------------------------------------------------ ------------FNVGEDCPVFDGMYEFCQLSTGGSVAGAVKLNKQAADIAINWAGGLHH AKKSEASGFCYVNDIVLAILELLKYHQRVLYVDIDIHHGDGVEEAFYTTDRVMTVSFHKY GEYFPGTGDLRDIGAGKGKYYAVNFPLRDGIEDDSYELIFQPVMSKVMEMYQPSAVVLQC GADSLSGDRLGCFNLSLKGHGKCVEFIKKYNLPLLLLGGGGYTIRNVARCWTYETSMALA VDIANELPYNDYFEYYGPDFKLHISPSNMANQNTPEYLDKIKTRLFENLRML-------- -------------------------------------------------------XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMYGILHKEDQAHDDSIWSCAWTRSEKDG TENIVTGSVDDLVKVWRWTGLELRHTLEGHQLGVVSVDVNISGVLAASSSLDSHIRVWDL ETGK--------------VKFTRCGQYFVTGTYQGTIDFFKAENGDSVSESSHHTKPVIS LACG--MSHVVSGGEDCAISVFDIGTRRILTGHTGPVTGLAFNPDCTKLVSASKDMSMSI WDMYNLS-------------------------------------------AHTFFDHLDQ VWCTTYNTSGTKIVSVSEDRAL-------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXVVRVRGLPWSATAEEIQEFFP------GSRGIHLTY NRDGRPSGEAYVELTNDKDLESALSKNNQHMGKRYIEVFKSKESEMEWVVKRSGSNQDAV VRLRGLPFGCSKEEIAHFFSGMEIVPNGITLIHDGQGRTTGDAYTQFASQDIAESAQQKH KEKIGHRYIEIFKSTLAEARANYVSQTGHCVHMRGLPFAANEQDILDFFSPLNPVNVVIH FNEGRASGESDVDFATHEEAKEAMKKDKAAMQHRYIELFYQDKEKPAMIRGSNITAAKAV ADAIRTSLGPRGMDKMIQSPGGDVTITNDGATILKEMKVLHPAAKMLVELSKAQDVEAGD GTTTVVVIAGSLLDACQKLLAKGIHPTTISESFQKCATKATEILESMSTVLELSDRESLL KSATTSLNSKVVSQYSNTLSPITVDAVIRVIDPATATNVDLRDVKIVKKLGGTVEDTELI DGLVFPQKSTGIGGPNKIEKAKIGLVQFCISPPKTDMQNQVIVSDYTQMDRVLKEERKYI LDIVKQVKKAGCNVLLIQKSILRDAVNDLALHFLAKMKIMVVKDIEREDIEFVCKSLNCK PVASVDHFTPEMLGFAELVEEVQTGSSKVVKITGIANPGKTVTILVRGSNKLVLEEADRS IHDALCVIRCLVKKRALIAGGGAPEIEVALRLHDYANTLTGMEQYCFKAFAEALEVIPFT LSENAGLNPIATVTELRNRHAKGEKTAGINVRKGAITNILEENVVQPLLVSTSAIHLASE TVRSIMKIDDIVNC-MILLEINNRIIEETLTLKFENALNGNKPELVDITIADFDGVLYHI SSPDGDKTKIRVSISLKFYKDLQEHGADDLIQREYGPYFSSAEDGYNVSLVYSDSISKDY KDVVKKAGLLKRNCFASVFEKYFEFQNKHKRAIIHYRDDETMYVDAKKEKVTVIFSTVFK DDDDIIIGKVFMQEFKK------------------------------------------- ---QDNTINLIHTLRDYLHYHIKCSK---------------------------------X XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKTTFGPLSDEDRIF TNLYGRHDWRLKGAMARGDYYKTKEILLKGHEWILKEIVTSGLRGRGGAGFPTGMKWGFM NKPSDGRPKYLVVNADEGEPGTCKDREIMRHDPHKLIEGCLISGRSMGVRAAYIYIRGEF YNEASNMQLAINEAYQAGLIGKNACGSGYDFDVYMHRGAGAYICGEETALIESLEGKQGK PRLKPPFPADIGVFGCPTTVSNVETVAVAPAICRRGGEWFASFGRERNRDVLMDFDALVD VQSGLGTAALIVMNKQADMIRCISRLIDFYKHESCGQCTPCREGCAWMSKIMHRFVDGNA QPAEIDMLYELSKQIEGHTICALGDGAAWPVQGLIRHFRPELEERMKQF----------- ------------------------------------------------------------ NYQDDADLATRAIPELTKLLNDEDQVVVSQAAMMVHQLSKKEASRHAIMNSPQMVAALVR AMSNTNDVETTRCAAGTLHNLSHHRQGLLAIFKSGGIPALVKLLS--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------GALHILGREAHNRAVIRGLNCIPLFVQLLYSPVENIQRVAAGVLCELAAEKE GAEVIEQEGATAPLTELLHSRNEGVATYAAA----------------------------- -MSADLQWMIIRNNSSFLLKGSNFSTEPNNLRSRNSFRYNGLIHRKTVGIEGASDGKGVV LVTRKNWRKPNKAFTRTELKKGSRRTLNTLRKILGNNRYRKDLKMAALRRASAVLRSQKP VVAKKARDEPYYCSAQINIPPELPDILKQFTKAAIRTQPKDVLGWSAAYFRALANGETPP VKERLEMPVATQKTDTGLSPGLLRVLNKQLGPRKVVDLSVIEEKWKDLALPKEQFDELVR IGGFGGSVEWTKFFSLACSALGENITDAMKTVCEILTADPDGGPARIPFQLFKDLYKYLA TVDGEISQEHMDEVMNHLQYDVDKQEGMVQPRNFLSPDCPSLSGKIDASQRDNLMESVKA QIAVANAQELLQKMSDKCFKKCVNKPGTSLDNSEQKCIAMCMDRYMDAWNIVSKTYATRL QRERSKMMNRLFGRGKPKEPPPDLNDTVANLDSRGESVEKKIAKLDGELKKYQLQMKKMR DGPSKNLVKQKALRVLKQKRVYEQQRDNLMQQSFNVEQANFGIQSVKETKQVVDAMKVGV KEFKKEYKKVDIDDIENVQDDLEDLMEQANEVQEVMGRSYGMPDVDDDELEAELDALGDD IALDEDASYLDDAAAAPNAPTSIPGADSVTNKDGVPVDEFGLPQLPS-XXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEDEDD DEFVDMGMEPEPNSKHDVEEFPFEVLTTEEIVQHMVDCIKEVNAVVEIPATITRILLNHF KWDKEKLMERYYDGDQDRLFSEAHVISPHKRPTEVICEICFMMLPSMMTGLECGHKFCTQ CWTEYLTTKIMDEGMGQTIACAAHGCDILVDDATVMKLVTDPRVKLKYQQLITNSFVECN RLLRWCPTPDCGHAVKVTCYDSKPVTCICSHIFCFACGENWHDPVKCKWLKKWIKKCDDD SETSNWIAANTKECPKCQVTIEKDGGCNHMVCQHCKADFCWVCLGPWEPHGSSWYNCNRY DEEEAKKARDAQEASRAALQRYLFYCNRYMNHMQSLKFEHKLYASIKQKMEEMQQHNMSW IEVQFLKKAVDILCLCRQTLMYTYVFAFYLKKNNQSIIFEDNQKDLENATEQLSEYLERD ITSDILVDIKQKVQDKYRYCESRRKVVLDHVREGYDKDLWEY--MATTDGKLSTTDRIIK GVPFPPSHRLTMSEVFDAKGKPRPEVLKQHFIVEGRVTEDVALRIINEGAALLRQEKTMI DIEAPVTVCGDIHGQFYDLMKLFEVGGPPATTRYLFLGDYVDRGYFSINERVYDACMEAF DCLPLAALMNQQFLCVHGGLSPEIHNLDDIRKLDRFKEPPAFGPMCDLLWSDPLEDFGNE KTTEHFSHNSVRGCSYFYGYAACCDFLQQNNLLSIIRAHEAQDAGYR------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------V TKNLVPGDAVYGEKRISVEEGIKIEYRAWNPFRSKLAAAILGGVDNIHMKPGTKVLYLGA ASGTTVSHVSDIVGPEGLVYAVEFSHRSGRDLINVAKKRTNIVPIIEDARHPHKYRMLVG MVDTIFADVAQPDQARIVAINAHHFLKNTGHVVISIKANCIDSTAAAEAVFAGEVTKLRE EKIKPQEQITLEPYERDHAVVVGQYRPPPKK----------------------------- ------------------------------------------------------------ ----XXXXDLQMVNISLRVLSRPDAAMLPQMYRQLGTDFDERVLPSICNEVLKSVVAKFN ASQLITQRQQVSLMIRKQLTERARDFNIILDDVAITELTFGREYTAAVESKQVAQQQAQR AQFDVERAKQERQQKVVQAEGEAKAAKMIGEAI--------------------------- -----------------------SYTGSSSDEDDVNPREKDQKSSKGFGDFCVRLDVYAF GRREIEIAEQEMPGLMALRKRAKGDKPLVGAKIVGCTHITAQTAVLLETLAALGAQVRWS ACNIYSTQNEVAAALAEAGFPIFAWKGESEDDFWWCIDKCMNHENWQPNMILDDGGDATH LMLKKYPAMFSLIKGIVEESVTGVHRLYQLSKSNKLTVPAMNVNDSVTKTKFDNLYSCKE SILDALKRTTDVMFGGKQVAVCGYGEVGKGCCAALKGLGAVTMVTEIDPICALQACMDGF RTVKLMEVVRQVD-----------------------------------IDVNSLRTPDLT WEKVRSQVDHIIWPDSKRIILLAEGRLVNLSCSSVPSFVVSVTASTQALALIELFNAPPG RYKQDVYLLPKKMDEYVASLHLPSFDAHLTELSDDQAKYLGLNKAGPFKPNYYRYPDPDA IKMFVGQVPRSMDENDLRKMFEDFGPIYQLNVLRDKITGQSKGCCFITFYTRKSALDAQN KLHNIKTMPGMQHPIQMKPADSEKRN-EERKLFIGMLAKKCNENDCRMMFSPFGTIEECT VLREQNNQSKGCAFVTYASRQCAQNAIKAMHHSQTMEGCRSPLVVKFADTQKXKEMKKIQ QMNNALGVQFAAGAIGGGLATYSTHWLDTIKVKMQTFPNLYHNGIFCLKDTMKQEGLRGL YQGAAPAVRAAVVFMCYGLCEDFVKATGVVASVVLCPLEIIKCRLQAMLRDIMRHEGVPG LFRGLTGMWAKDIPGSFVYFGSYEFSRTMLRVMEH-SETLGHGVFMSGVFAGLC-YCIMH PFDAVKTRVQVRTEGVASLYSGMKPYMLRAAVYSGIQFMAYEHVKTFI------------ ------------------------------------------------------------ ----------------------------------------IETDTALIEEREDQIRQLEG DILDINEIFRDLATLVHEQGETINSIEDNVVMDQVNAGNEQLSQASKYQKKEK------- -------------------MVNVMKGVLVECDPAMKQFLLHLDETNALGKKFVIQDLDDA HIFIASDMVE-----------------SKKKDQAPTAQEAIQKLRETEEMLEKKSDYLEK KIAQELGTAKEKAALMALKRKKRLEKQLQQIDGTLSTIEFQREALENASANSEVLKNMGY AA-ALKAAHQQLDVDDVHDLMDDIQEQNELAEEIGQALSQPAGFGQDVDDDELMAELEEL EQEGLDEQLLDVQSLPDVPTAEDDDMKELAAW---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------PDKTTITEAHHIWPSLSDDEWIKVEVQLKDLILADYGKKNNVNVASLTQSE IRDIILGMEITAPSAQRQQIAEIEKQTKEQSQLTATTTRTVNKHGDEIITSTISNYETAT FSSKTEWRVRAISATNLHLRTNHIYVSSDDIKETGYTYILPKNVLKKFIIISDLRAQISG YIYGVSPPDNPQVKEIRCIVMPPQWGTHQTVHLPNMLPGHEYLKEMEPLGWIHTQPNELP QLSPQDITTHAKVMSDNPGWDGEKTVVITCSFTPGSCSLTAYKLTPSGYEWGRQNTDKGN NPKGYLPSHYEKVQMLLSDRFLGFFMVPGQGSWNYNFMGVRHDPNMKYELQLANPKVFYH EIHRPSHFLNFSSLEEGTDREDLY----ATRPNLSINKDTRVICQGFTGKQGTFHSSQAI EYGTNMVGGVSPGKGGTKHLDLPVFNSVAEAKEATGATASVIYVPPKFCAAAIMDAINAE MPLVVVITEGIPQQDMVKVKQLLLKQNKTRVIGPNCPGIIRPGECKIGIMPGHIHMKGKI GIVSRSGTLTYEAVHQTTQVGLGQTLCIGIGGDPFNGTNFIDCLDVFVNDPQTEGIVLIG EIGGRAEENAAQFLKDNNGPNRKPVAAFIAGLTAPPGRRMGHAGAIISGGKGGAEEKIEA LRDAGVEVTMSPAQMGASILRAMEAAGRASSEALKCTLCHERLEDTHFVQCPSVPEHKFC FPCSRESIKRQGAGAEVYCPSGKKCPLVGSN----------------------------- ----------------QSNVLVDGPCTGVTRKAMSLKRLHLTKFKLFPYGARTSVIKKTW EKADTNKQFAETEWAKKIAKREKRATLSDFDRFKLMKAKQQRNRAITLELGRLKKQARKT CPLLLRVFCSTGRHNAMNEYSRGNTPANELQIYTWMDATLKELTSLVKEVNADARRKGTF FDFAIVFPDNRTPTYRLREIGTTCAGRKGQDDATTLASKRFNIGDYLDIAISPPRGLGKT LQTISLIGYMKHYRNIASPHLIIAPKSTLHNWMAELERWVPSLKAVCLIGAQEKRATFIR DILMPGEWDVCVTSYEMCIREKSVFKKFNWRYLVIDEAHRIKKEKSKLSEIVREFKSANR LLLTGTPLQNNLHELWALLNFLLPDVFNNSEDFDAWFNTNSCFENNVLVERLHEVLRPFL LRRIKSDVEKALLPKKETKIYIGLSKMQREWYTKILMKDIDVVNGAGKSDKMRLLNILMQ LRKCCNHPYLFDGAEPGPPYTTDQHLADNCGKMVLLDKLLPRLQAQGSRVLIFSQMTRVL DILEDYCFWKGYNYCRLDGQTPHEERQISIDDFNHPNSEKFVFMLSTRAGGLGINLATAD IVVLYDSDWNPQVDLQAMDRAHRIGQTKQVRVFRFVTDNTVEERIIERAEMKLRLDNIVI QQGRLVDQQNNKEVLNMIRHGAEMVFASKDSAITDEDIDTIMERGEKKTEELAQKMGDMG ETGLRNFTLDTPDSSVYQFEGQDYREKHNKGGIGHWIEPPKRERKANYAVDAYFREALRV SEPKAPKAPRPPKQPNVQDFQFYPPRLFELLDREIYYYRKNIGYKVPKNPEYGVDAERIR KEEQEKIDEAEVLTEDEIAEKEDLLKGFTNWSKRDFNQFIKANEKYGRDDIESISKEVEG KTPEEVMEYSSVFWERCNELQDIEKIMAQIERGEAKIQRRISIKKALDAKMARYRVPFHQ LRIQYGTNKGKNYTEEEDRFLVCMLHKLGFDKENVYDELRTSVRQAPQFRFDWFIKSRTA MELQRRCNTLITLIERENLELEEKEKAERKK----------------------------- ------------------------------------------------------------ -----------------------------------------------------GKYVPPS MRDGASRRGESMQPDESATIRVTNLSEDTRESDLQELFRPFGTISRIYLAKDKITGQSKG FAFINFHRRDDAARAIAGLSGYGYDHLILNVEWAKPSXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX-------------------------------------------------------NL DKPANPSSHEVVAWIKRIFEVSKTGHSGTLDPKVTGCLIVCVERATRLVKSQQSAGKEYV CIFRLHSAVENEKKIYQAVETLTGALFQRPPLISAVKRQLRVRTIYESKMTEYDKERNMG IIWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGIQSEKEGLVTMHDVLDAQWLYD HQKDETYLRRVIKPLEALLISHKRIILKDSAVNAVCYGAKIMLPGV-------------- ------------------------------------------------------------ ------------------------------------------------------------ ---QQRSQQAINAAQRQGISIETEKKFAGGSNKQHSANKNTAKLDRETEELHHTAVSLDV SRLIQQGRQAKNMTQKELATKINEKQQVINDYEAGKAIPNQQVIGKLERAL--------- -------MLKPKALTQVLSQANTGGVQSTLLLNNEGALLAFSGYGDKDARVTAAIASNIW SAYEKHGKAAFNEDKLQYVLMECEEGRVAITRVANLLLCIYAKETVGFGMLKEKAKALAE YLEEPLTQVAASNQATARIQTKKQTLDDAYAIPANFLEIDVASPEGKNRYTDYEVRMKTN LPVFKVKESSVRRRYSDFDWLRQELERDSKIVVPKLPSKSLFKQLPFRGDDGIFEEEFIE ERRKGLEEFVNKIAGHPLAQNERCLHMFLQEPVIDKNYVPGKIRS--------------- ------------------------------------------------------------ -----------SVTFLSNQENGTLYSIPGLDYVGHEDVLPYATTEKQPIQNHLFDKFLAL DNKFMAKNTLREWQLKNHPWLELTDVH--------------------------------- ------------------------------------------------------------ -------------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXX------IRRKKITVFTDAKEDTTINELKKSIEQITKKGPDD MRFYKDHKKLQECGFTSSTARAQAPATIGMSFREFENLEITPLSTPPELPDVMKSPETAS HQPE-HLYRYHAVLLRARFEENKN-DPIEAKRVLEAGEEELFQKSHPQPFKFPSSPGGAA FGRDIKPPDWSYDLWHPLERAAYPEYF--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------VPVRTYTHEVVTLWYRAPEILLGSRFYSTPVDVWSIG CIFAEMITKRALFPGDSEIDQLFRIFRTLGTPDDTLWPGVSQLPDYKASFPKWPAQETRE IVDKDGHDLLAKMLTYEPSRRISA---------AFKLFNTLGKVGIGLAITGGVVQSALY NVDGGHRAVIFDRFSGVRETVVGEGTHFLIPWVQRPIIFDIRSRPRNVPSLTGSKDLQNV NITLRILFRPISARLPGIYTSLGEDYDERVLPSITNEVLKAVVAEFDASELITQRESVSQ RVNEDLTKRAESFGLILDDISLTHLTFGKEFTEAVELKQVAQQEAEKARYIVEKAEQQKL AAIISAEGDSQGAILLSKAFGDAGDGLVELRKIEAAEDIAYQMSQSPNVVYLPQGQQTLL SLPMKTIHSSQTVTIPDGVEIWVKSRKVTVKGPRGVLRRSFQHLSIDISKPTKNTVLVEK WFGIRCELAAVRTVCSHIMNLIKGVTKGFRYRMRSVYAHFPINVAISENDTLVEVRNFLG EKYTRRVKMLSGVTCMNSTTQKDELILEGSDIERVSRSAALIQQSTTVKRKDIRKFLDGI YVSKK------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------MKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSALAICFPE YQGSNTYEEAAAYIQVQFNKRKDTKEIYTHF------------FDAVTDVIIKNNLKDCG LF-----------LKDSRINKKDREKKKRKKANPQNMTIRELPQASSALFFKYNTQLGPP YHILIDTNFVNFSIKNKLDIVQSMMDCLYAKCVPYITDCVMAELEKLGSKYRVALRIAKD PRFERLSCMHKGTYADDCLVQRVTQHKCYIVATCDKDLKRRIRKIPGVPIMYLAQHRYSI ERMPDAFGAPK------------------------------------------------- ---------------------------------------------------------EEM EIDGTVEIPSSKATVLRGHESEVFICAWNPTNDLLASGSGDSTARIWNMNDNSNANQLVL RHCIQKGGTEVPSNKDVTSLDWNCDGTLLATGSYD------------------------- ---------ILSAGVDKTTIIWDASSGHCTQQFAFHTAPALDVDWQSNISFASCSTDQCI HVCKLGVDKPIKTFQGHTNEVNAIKWDPQGTLXXXXXXXMTLKIWSMQQDSCVHDLQAHS KEIYTIKWSPTG------------------------------------------------ ------------------------------------------------------------ ---SNNDLAQLFECPVCFDYALPPIMQCQSGHIVCSSCRPKLTCCPTCRGPLGNIRNLAM EKVASTVMFPCKYASSGCPETLLHTEKSEHEETCEFRPYCCPCPGASCKWLGSLEQVMPH LMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHNFMLVLEKQEKYDGLQQFYA IVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHDGVQSAIINSDCLVFDTNIAQLF ADNGNLGINVTISMC--------------------------------------------- ----------------------------------------------GRTADFFFMFLFGG TLMTVTVNLVFLGQAFTIMLVYIWSRRNPYVRMNFFGLLNFQAPYLPWVLLGFSLLLGN- ------------------------------------------------------------ --GLELLSDQGFRIDGRRPNELRRIQCRMGVFGQADGSAYIEQGNTKVLAAVYGPHEVR- QKSKHDKVLINCQYSMAVFSTGERKRRPRGDRKSIEMTQHLKQTFEAAILTELYPRSQID IYVEVLQSDGGNYCASVNAATLAIIDAGIPMKDYVCACSASHIEDTPIVDINYLEESSGP ELIVATLPKSDQIVFLEMNARLHEDHLSKVLDTATKGCKDVYHILHAVVKDMSGNYYFGI VGHHDNPVFEMEFVPPNKTSEPKKDDHRHLNQFIAHAALDLVDEQMWMTSNMYLKIVDKF NEWFVSAFVTAGRMRFIMLHDMKNEDGIKNFFTEMYETYIKLSMSPFYEPNSAIKSASFE KKAQFYGRKYL--------------------------DRKAFTYMMVAAGTIPAAYAAKT MVTQFVSSMSASADVLALAKIEIKLADIPEGKNATFKWRGKPLFVRHRTAEEIETEQGVD LAELRDQQHDHERVQKPEWLILIGVCTHLGCVPIANAGHFGGYYCPCHGSHYDASGRIRK GPAPLNLEVPVYVFPDEEIVIVG------------------------------------- ------------------------------------------------------------ ---------------------PEGHNNLNYSDILCGVLRGALEMVQLEVDVRFTQDHLKG DNITEIRLKFIKRLEDAVPAGED------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVY EMAAGYPPFFADQPIQIYEKIVSGRVRFPSHFSGDLKDLLRNLLQVDLTKRFGNLKNAVN DIKNHKWFSTTDWIAIYQKKVEAPFTPRCKGPGDPSNFDDYEEEPLRISQTEKCAKEFAD FXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-- ------------------------------------------------------------ ------------------------------------------GLAERRGWGQFLFRPKLG EQPKDHKFYHRLYPQIIQDIERIENNWRTGRHTLQRIHCRSETSKGVYCLQYDDQKIVSG LRDNTIKLWDRNTLECVQVLTGHTGSVLCLQYDENIIISGSSDSTVRVWSVKTGEMLNTL IHH--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKS FENIRNWIRNIEEHASQDVEKMVLGNKCDMNDRRQVSKDRGEQLAVEHGVKFMETSAKAS INVEEAFFSLARDIKAKMDRKL-DGESSADRNVEIWKIKKLIKSLEAARGNGTSMISLII PPKDQISRVAKMLADEFGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPGNGLVIYCGT IVTDEGKKKKVNIDFEPFRPINTSLYLCDNKFHTEALTALLADDNKFGFIVMDGNGALFG TLSGNTREVLHKFTVDLPKKHG------------------------------------XP NVAGLVLAGSADFKTELSQSDMFDPRLQAKILKIVDVSYGGENGFNQAIELASDALANVK FIQEKKLIGKYFDEISQDTGKYCFGVVDTLKALEMGSVEILIVWENLDIQRYVLKNHQTD EEKILFLKPEQEKDKTHFTDKETGVEMELADSQPLLEWFANNYKTFGATLEIITDRSQEG AQFVKGFGGIGGILRYQVDFQGMEAYDELVDDWDPDDY---------------------- ------------------------------------------------------------ -----------------------------------------ENNKTSVLTHCSDGWDRTS QLTALAMVMLDPFYRTIRGFEVLIEKEWLSFGHKFGQRIGHGEDKHSDADRSPVFLQFVD CVWQMTKQFPNAFEFNEHFLISILDHLYSCLFGTFFHNSEQQRVKEDLKVRTVSLWSYIN CQLEEFTNPLYQHVLFPVASMRRIELWTGYYIRWNPRMRPQEPIHLRNRELLILKAQLQK RVDELQRELDAKN---RTFIPHVPFDLVQCESAFPRAKPAADDKSFTEALLKRNQDLTPT ATEQSAVLNLATKVNTVIDNLIINPGAFDAAVIEEVRQVGSHKKGTMMATHNVADIVVIL KTLPTVEAVQALGNKVMEDLKTSDPAEVLSMLTNESGFELSSSEATVKVLITTIPPNLKK LDPELHLDGKIMQGHLAAIRHARWFEENAFHSSIKVLIRLLRDLKNRFEGFEPLTPWIIE LLAHYGIMSNPTRQPLAINIAFRRCLQLLAAGFFLPGSCGITDPCESGNTRVHTVMTLEQ QDQVCYTAQTLLRVLSHGGYKQILGIEGNASIATEMSVWEGVVVTPSDKAYEKPEKXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXMAQTVQLAPRLVDKVVPKLQTFWHYAKVELRPPQEWPEIQ KGFTNLVQAKTQKWRNVTVQEATLVAVEVACWFFVGECIGKGALVGYQIPGAVDFEAH-- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------PLRTG KVKIQDILACSFLDDLLELRDEDLSKDMQXXXXPLRPGALRVYGQYLNLDKDHNGMLSKE ELARYGTGTLTDVFLDRVFQECLTYEKRKKYR---------------------------- ------------------------------------------------------------ ---------------------TEVVRGQMFDVGPRYKTLQYIGEGAYGMVVSAMDTTNTN KVAIKKISPFEHQTYCQRTLREIKILTRFKHENIINIQDIIRATTIEKXKDVYIVQCLME TDMYKLLKTQKLSNDHVCYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFG LARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDVWSVGCILAEMLSNRPIFP GKHYLDQLNHILSVLGSPNQEDLSCIINDKARSYIQALPFKTQVPFSKLADHKALDLLGK MLTFNPNKRITVEESLAHPYLEQYYDPQDEPVEEEPFTFEMELDDLPKERLKEMLFDET- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------DSMHDATYDRNT-----LARIAMLCNRAEF KTGEDNVPVLKRECNGDASESALLKCVELSIGQVIEFRKANKKICEIPFNSTNKYQVSVH ANEPRYLLVMKGAPERILDRCSTIYIHGEEKPLTEEWREAFNQAYLELGGLGERVLGFCD YILPSDQFPMGYPFDADEENFPLTGLRFVGLMAMIDPPRAAVPDAVGKCRSAGIKVIMVT GDHPITAKAIAKGVGIISEGNETVEDIAARTNTAVQNINPGDAKACVVHGSDLRDMTPAQ IDDILQNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIA GSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLVFILAD VPLPLGTITILCIDLGTDLVPAISLAYEQAESDIMKRMPRDPLTDKLVNQRLISMAYGQI GMIQASGGFFTYFVIMAENGFWPGRLLGIRKEWDSKGTNDLEDSYGQEWTYAQRKVLEYT CHTAFFMSIVIVQWADLCICKTRRNSILHQGMSNHRLTFGLFFETTLAVFLAYCPGLDKG LRMYPLRWTWWIAPMPFSVLIFLYDEGRKYILRRDPGGWVEQETYYSFRNLTKGKKIAAS LTAGGIGMGVALHELELHPAHLPWSHHGMLSSYDHMSIRRGYQVYKQVCAACHSMNYLCY RNLIGAFMTEDEAKAEALEVAVLDGPDDTGEMFERPGKLADRFPNPYKNDEAARAANNGA LPPDLSYITMARHGGEDYVFAVLTGYCDPPAGVELAEGQHYNPYFPGGAIGMAQALYNEI IEYDDGTPATQSQLAKDVCVFLQWAAEPEHDTRKR------------------------- ------WIRPDLPSRCTYSTSKQTESPHRHLKKRPKILPNILHMIGETPLIRINNIGKSF GLKCELLVKCEFFNAGGSVKDRIGLRMIEDAEKDGTLKPGDVLIEPTSGNTGIGLALAAA VKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTSASFDSPESHIGVAQRLLNEIPNSHI LDQYRNPSNPLAHYDTTAEEIVDACEGRLDMMVCSAGTGGTLTGISRKIKEKFPASKVIG VDPEGSIIAEPEDTSFYEVEGIGYDFIPTVCDRSYTDKWFKSNDKESLKMSRRLIREEGI LCGGSSGAALSCAIKAIKHYDLKEGQRCVVILPDSVRNYMTKFLSDDWMKEREF------ ------------------------------------------------------------ ----------------DGSKYEGSWVEDQRCGYGKYYYINGDTYEGEWQNHVRHGQGAYT YAETGTKYTGTWKEGKREGAGELVHANHKYAGPFRDDRPEGKGKYVFDIGCQQHGEYIMP DIMRLITKDLSEPYSIYTYRYFIHNWPKLCFLAMQGKKCIGAIVCKLDMHKKMVRRGYIA MLAVDDQYRRRKIGSHLVMKAIKAMVADDCDEVVLETEISNKAALRLYENLGFVRDKRLF RYYLNGVDALRLKLWLRTIDGLRFHLSPNQKKCLKEEIHKDVLVTGEYELSEAPGQKTHL HVSDSKGHTLYNKEDATKGKFAFSTEEYDMFEVCFETKMPGGGHGADREVFLNMKHGVEA KDYAAIAKAEKLKPLEVELKKLEDLSESIVNDFAYMRAREEEMRDTNESTHSRVLYFSIF SMCCLLGLATWQVLYLRRYFKAKKLIE--------------------------------- ----------------------------------------VSASSGIVGTTKEHLGFALA LKVPVMVVVTKIDMCRQAQVERVVTQLERILKSPGCKKVPMRVENEDDTLTAALNFDTNR VTPIFTVSCVTGQDLELITKFLNVLPPLQSQELAEHQVDEVYTIPGVGTVAWGNLVRGTI REG--------------------------------------------------------- --------EADVFLLFHASYICTGFQTTIHVGNVCQTASIVIMSKDMLKTNDKAVVRFRF LNRPEFIRVGSRLLFREGRTKGMGEVTSICP----------------------------- -------------------------------------DTASGEELHTLEGHRNVVYAIAF NNPYGDKIATGSFDKTCKLWSAETGKCYHTFRGHTSEIVCLAFNPQSVVATGSMDTTAKL WDVICTLNGHSAEIISLAFNTTGDQLITGSFDHTVSVWDKRIHTLIGHRAEISSAQFNWD CSLIATGCMDKTCKIWD------------------------------------------- ------------------------------------------------------------ -----------------GDVFMEKHWKSVIHRSICDYFFEAQGKAGSPEDVLPVIATPHH YLINIYRNSLYVVAVTTTEAPPLFVIEFLHRVLDIFEDYFTECTESIIKENYKIVYELLD EMLDNGFPLATESNILKEMIKPPNLLRTITDTVTGKSTSVSATLPTGQLSNVPWRRTGVK YTNNEAYFDLIEEVDAIIDRSGSTVFAEIQGYIDCLIKLSGMPDLTLSFVNPRLLDDVSF HPCVRFKRWESERVLSFVPPDGSFRVISYHIGAQNMVAIPVYLKHSISYKDGSSGRLDIT VGPKQTMGKPVENVVLEIPFPKAVLNVTLTPNQGKYSFDPVTKLMTWDVGKIDTTKLPNI KGSINLQSGAPPPESNPTISVQFTINQMAVSGLKVNRLDMYGEKYKPFKGVKYVTKAGKF QVRTMATYVKPATRYATSDWYTSNYAISTNAERQRSASHDIRQEGRFLRNETDNKTAWDQ ADNNTRLSDRVLNIRKWKDILETTLADTEKEIADLSEAKENTEIALESMNLPTDVNIENM VTREGRQNIDVVEDEVEDQLHKENQVIDGIKKQLQQKVAEGTEQLHLLQEARQQLLLDLQ DKNIALEIDVDQYNLTEESPGISFKPDPLRVPKGSTTPQNWEDFSRYNKDRAEAEMNASR HLREAIHHTIQQTRNDLDAQQTATDYAYRRRMHDMKKAIDELNWQKQQLEEEIAELENDI RGLNDKIRAKINPMKLAQTRLENRTYRPNVELCRDNVQYGLTDEVKQLEASKQALEEKLR QSQHALHQLEQNLHRVNDDLQCKANSLKLDENCMMSRSKM---------TNLKDVLADLI PKHQKTVKELRKKHDNTVVGEVTVGMMYGGMRGIKGLVTETSVLDPDEGIRFRGYSIPEC QKLLPHAPGGEEPLPEGLFWLLCTGDIPSEAQVKAISKEWANRADVPSHVVTMLNNFPTH LHPMAQFSAAITACNSESKFCKAYGDGVHKTKYWEYVYEDSMDLIAKLPTIAAIIYRNMF RDGTSVGAIDPDKDWSGNFVSMLGFENPEIFELMRMYLTIHSDHEGGNVSAHTCHLVGSA LSDPYLSFAAGMNGLAGPLHGLANQEVLTWLQKAKLSEGHLKEFIWKTLKGGQVVPGYGH AVLRKTDPRYVCQREFALKHFPNDPMFTLVSNLYKIVPDILLEQGKAKNPWPNVDAHSGV LLQYYGLTEMNYYTVLFGVSRALGCLSSMVWDRALGLPIERPKSISTEHLIKMVQ----- --------------AAERQEAGKRIYHKLCFKCSICKMSLNLNNYAQADGTIYCKNHYAS EVVAKNAQ---------------------------------------------------- ---------------------------EVATFYTMFNREPVGKYHVQICTCTPCMLGGVG SDVILEALKKKTGINPGETSKDKMFTLVEVECLGACVNAPMVQINDNYYEDLTVKDMEEI IDDLKAGKVPKAGPR---STRFACEPTGKLTSLSTPPTGPGF------------------ -----------------------RLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHS EKKLTLVFEYCDQDLKKYFDSCNGDIDPDAVKSFMYQLLRGLAFCHSHNVLHRDLKPQNL LINKNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIF AELANAGRPLFPGNDVDDQLKRIFKLLGTPTEDTWPGMIQLPEYKPYPMYNVNQQVVPKL NAKGRDLLLNLLICNPARRMSAEEGMQHLY------------KFFTTNGPRDDINYPISG EC-SMPVEYCEYHPSYDRCKAWMEKNLPEELKEMLLKRQSRGGRGVIKARKKTEPQTVSL FRSNRGKKKFMTVISGLGTYDIDLKEASKFFANKFSCGSSVTGEDEIVVQGDVKDELFDL ITEKWPQISEDNIEDKGDMKR--------------------------------------- ---------------GFSGVYVPDKETLVTDAGKLDVLDTLLARLKNEGHRVLIYSQMTR MIDLLEEYMWHRKHTYMRLDGSSKISD--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---NCEEYLHMKNNRDAVYDCTSSSFDGILSLMSPEDSWVAKWQRINRFTKGCYAISVTG RLPPGIIRELKSKGITYRSHDTSMPRFGTYLTKEKEDELRDIANRIVAPGKGILAADEST GTMGKRLQNINVENNEDHRRQYRQLLFTALSSHISGVIMFHETFYQKADDGKVFTQTLID QGIIPGIKVDKGVVPLAGSVEECTTQG--------------------------------- ---------------------------EPEILPDGDHDLETTQKITEQVLAHCYKALSDH HVFLEGTLLKPNMVTAGQSCSKKYTPEQVAKATVTALSRTVPPAVPGITFLSGGQSEEDA ------------------------------------------------------------ -------------------------------------------IESKFYEEVHELECKYA EKYAPLYERRKEVVTAGIEPTDSDCDWPSDEEEETE------EENPNGVPNFWLTIFKNV DMLSEMVQDHDEPILQHLQEIKVKFTMGFKLEFYFEANEYFTNTLLTKEYILRAEPEEGD PFSYEGPEIVKCTGCTIDWAKGKNVTVKVIKKTQKHKGRGTKRTVTKTVQNDSFFNFFSP PEIPEGEADEDAEALLAADFEIGHFIRERIVPRAVLYFTGEALDEEEEEDEN---IILLK EGTDSSQGTPQLISNINACQAIVDAVRTTLGPRGMDKLIVDSQGRATISNDGATIMKLLD IIHPAAKTLVDIAKSQDAEVGDGTTSVVLLAGEFLKHCKPFIEEGVHPQITVRAFRKATQ LAVEKIKQIAVTIKKDPKEARQLLLKCAATALSSKLVAHQKNFFAKMVVDAVMLLDDLLP LSMIGMKKVQGGALEESRLIGGVAFKKTFSYAGFEMQTKKYKNPKIALLNVELELKAEKE NAEIRVDNVEEYQAIVDAEWKILYDKLDRIHQSGANVVLSKLPIGDVATQYFADRDLFCA GRVPEEDLKRTMKACGGSVQTTTANL----------------------------XXTIIM RGGTEQFIAETERSLHDAIMIVRRAIKNDAVVAGGGAIEMELSKYLRDYSRTI------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------RARAIAPRPT-DIFRPAVRCPTIKYNTRVRTGRGFTLE ELKNAGFNKHQARQLGIAVDFRRRNRSVESLQLNVQRLKEYQSKLIVFPRKVTKPRKGDA TEEEMKLATQLTGPVMPITQAFKSEKARVISAEEAKFSAFNKLRQERAHKKLRGYREKKA REA--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------VGDVKDRVAILVDDMADTCGTVCHAAEKLLEA GATKVYSICTHGIFSGPAISRINNSMFETVVITNTIPQ---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------IHGDIEVACYGYEGVDAVKNALRSGLSLTTEEMPI KINLIAPPLYVMTTQTLERAEGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXILGSLNTNMSREGITTLPKGHCAACEKP IVGQVITALGRIWHPEHFVCVQCGDELGTRNFFERDGQAYCERDYHHLFSPRCAYCGGPI LDKCVTALDKSWHPEHFFCAQCGRTFGDDGFHEKDGKAFCREDYFDMFAPRCGGCAQPIM DNYISALNHQWHPECFVCRECRVPFGGGSFYDHDGMPYCETHYHAKRGSLCAGCHKPITG RCITAMYKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCHPCFVKLFXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXADQRKFFVGGNWKMN GDKHSMEGIITFLNKENPKTEVVVGPPTCYLEYVRGKLIGVAAQNCYKVAKGAFTGDISP AMIKDCGCEWVILGHSERRHVFGESDELVGAKVKHALESGLHLIPCIGEKLEEREAGKTN EVVFRQ--------------------------------XHQDLRKWLKENVSAQVAASVR ILYGGSVTAKNCKELGGKPDIDGFLVGGASLKPEFKDIINAR------------------ ------------------------------------------------------------ ----------------------------------------SFKDGLAFCALIHRHRPELI DYNKLSKDNPLENLNTAFDVAEKYLDIPKMLDPEDMVASAKPDERSVMAYVSSYYHAFSG AQQAETAANRICKVLKVNQENERLMEEYERMASDLLEWIRRTTPWLENRSTDNTLPGTQR KLEEFRDYRRKHKPPKLEEKARLETTFNTLQTRLRLSNRPAYLPTEGKMVGDIANAWKGL ETAEKGFEEWLLSELQRLERLDHLAQKFKHKCDIHEEWSYGKEDMLQAEDFKQCRLNELK ALKKKHEAFESDLAAHQDRVEQIAAIAQELNALDYHDVTTVNTRCQRICDQWDLLGTLTQ TRRTALEEAERVMERIDQLHLEFAKRAAPFNNWMDGAKEDLVDMFIVHTTEETQGLIDAH EQFKQTLGEADKEFNAIITLVQ-------------------------------------- XXXXXXLQQEMIRQQNNERLRRQFAQKANVVGQWIERHLDAVASV-MQRGSLEDHLNKLQ TVEKDVMGYKPSIDELERFNQEVQEAFIFENRHTPYTMETLRVGWEQLLTSVARNINEVE NQILTRDSKGISDQQMDEFRKSYFHFDKNRTRRLEPKEFKACLVSLGYNIRDNKQGEADF QRIMSITDPNHTGYVTFDAFLDFMTRETTDTDTAEQVMQSFKILAGDKPFITADILRREL PPDQAEYCIQRMAPY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------ELDYFSKALESPE RPFLAILGGAKVADKIQLITNLLDKVNCMIIGGGMAYTFLKVHNKMEIGTSLYDAEGAKI VEDILKKAAEKGVTIQLPQDFTTANDFKEDAKSGTATVAEGIPAGWMGLDCGPKTIVGSK ELIAKAKVIVWNGPVGVFEFEKFATGTKAVMDAVVEATKNGACTIIGGGDTATCCAKWGT EDKVSHVSTGGGASLELLEGKNLPGVAALTDAXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXKHRSRSKERKRSRSPKGKRKPYKYWDVPPPGFEHISPMQYKAMQAAIP FAGSAISRQARRLYVGNIPFGVTEEMMMDFANTQMHLAGFAQAEGNPIIACQVNLDKNFT FLEFRSVDETTQAMAFDGIIFQGQALKIRRPRDYQPLPGMAEMPSVGVVSTVVQDSPHKV FIGGLPNYLNEDQVKELLISFGPLKAFNLVKDSATGLSKGYAFCEYVDQACAGLNGMQLG DKKLIVQRASVGAKNAQQAPVQIQIPGLNLNQ-ATEVLCLMNMVAPEELEDEEEYEDILE DVKEECGKYGVVRSIEVPRPIKGIEVPGCGKIFVEFNSIIDCQKAQQALTGRKFANRVVV TSYYDPDKYHRREFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRLKVQIPDIKTSL DIVKHMKSKKGPVETQFLLSDQLYAKATIPPAEKVCLWLGANVMLEYDLDEAETLLVKNA ATKSLEQVDDDLGFIRDQTTTIEVNMARVYNWDVKRRQAEKGXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------ ------------------------------------------------------------ --------------------------------------------------GNSGPMRLYV GSLHFNITEDMLRGIFEPFGKIDHINLVMDNETGASKGFGFVTFHDAEDAKKALEQLNGF ELAGRPMKVGHVTERTAEASMLDSDEMDRAGIDLGATGRLQLMAKLAEGTGFQIPQVAAN ALNMSGAAAAPPIATQCFMLSNMFDPNVGAMRWDTEIRDDVIEECNKHGGVLHIYVDKAS PQGNVYVKCPSIAAAVASVQALHGRWFGGKVITAAYVPLPNYHALFPEATRANQLLLPS- DERDDEISPI--QHPKKRNRRGAVSAEVYTEEDAQSYVKKVVPKDYKTMAALSKAISKNV LFSHLDDNERSDIFDAMFPVHRHGGEVIIQQGDAGDNFYVLDSGEVDIYVNSE------- ---------------------------WVXDRDSYRRILMGSTIRKRKMYEEFLSKVSIL ENLDKWERLTVADALEPVQFEDAQEIVRQGEQGDDFFIITEGAASVLQRRNENEEAVEVG KLGPSDYFGEIALLLNRPRAATVVARGLLKCIKMDRDRFERVLGPCADILKRNISQYNSF VSLSV------------------------------------------------------- ----------------------------------------------------CYSRARDY CTSAKHVVNMCLNVIKVSMYLQNWSHVLSYVNKAEATPEVTEGKDGGQAVITKLKCAAGL AELATKKYKSAAKYFLQASFDHCDFPELLSANNVTMYGALCALASFDRAELQKNVISSSS FKLFLELEPQLRDILHKFYDSKYASCLRLLDEIKDNLRLDMYLAPHVNTLYTQIRNRALC QYFSPYLSADMNKMAVAFNTTLIAMEDELMQLILDGQINARIDSHNKILYAKDVDQRSTT FEKSVNMGKDYQRRTKALILRSAMIKNQLHVKSPPRD----------------MSQKSEI IDKAEDIADQVLRHGKHILPHVARLCLISTFLEDGIRMWFQWHEQRDYIDATWGCGWFLA TLFVLTNLVGQLGACVMVLSRQKVSIACGILFGIIALQTIAYSILWDLKFLMRNLALSGG VILLLAESKAEGKSLFAGLPSLGENTPKTYLQLSGRILLVLMFLTLLRFEFAFLQLVQNL VGTALIILIAIGYKTKLSALILVGWLTILNLYFNAWWNIPDYKPMRDFLKYDFFQTQSVV GGLLLVVALGPGGYSMDEHKKKWRHTVTVLPGDGTGPELMAHVREVFRYAGAPIDFEEVQ IDRNGVAIKGNINTNSKSRNVELRSELELFANVVWCRSIPGVDTRHKDIDLVVIRENTEG EYRQLEHENVDGVIESLKIITEVNSTRIAEYAFDFAERHGRRKVTAVHKANIMKLGDGLF LECCEKVSKKYPDIEFEAMIVDNCSMQMVSKPQQFDVLVLPNLYGMIIANIGVGLVGGAG VVAGANIGSDYAVFEPGTRNTGKKIAGKNIVNPTAMLLAGSDMLDYLGLTAHASIIRDSV MKVVSEERIHTPDLGGQATTTEMIQAIIKDI----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------HTHPVYCVNVVGTQNAHNLISISTDGKMCSWSLDMLSQPQDSMELQHKQSK VAVTSLSFLSGDVNNFVVGSEEGAVYTACRHGSKAGIGEAFEGHQGPITGVDCHSVPGQI DFS----------------------LHSFEDNSDYVYSVRWSPIHPALFASVDGMGRLDL WNLNNDTEVPTATKYNVALNCAEWHPSGHNIAVGDDMGKIHIYDVGEPVAVPR------- ------------------------------------------------------------ KKAQIQKSEWLTLGHGRYDEIASEKEFFDTCKKSKNVVCHFYRESTFRCKIINKHLEILA PKHIETRFVKIDVEKCPFLVERLRIVLLPTVCLAKEGKTVDYI----------------- ------------------------------------------------------------ ---------------------GAIDNPPKTPFVMGFECAGEIVALGENVENYAVGDKVIA LSNAWAELLAFVFKMPSGMSFQDGAALCMNYVTAYVMLFDIGNLRKGQSVLVHSAGGGVG HAVCQLCKSVEDVTIFGTASYKHDSIKNN-LTHLFDH-VVDYCQEIRKVSPEGVDIVLDS LCGDDTNKGIGLLKPLGKYILYGSANIVTGETKSFFSFAKSWWQVDKVNPIKLYDENKTI SGFNLRQLLIVNKLFKMYAEGKIRPQVDSAWALEDIGDAMQKMHDRKNIGKILLDPSLMS RKQTPSEFLKQIIGRPVVVKLNSGVDYRGVLACLDGYMNIALEQTEEYVNGQLKNKYGDA FIRGNNVLYISTQKRRI---SRAVLLLKQQLSELTKNPVTGFSAGLVDD-DLFLWEVLII GPSDTLYEGGFFKCHLTFPKDYPNKPPKMQFMSEIWHPNIEKTGE--------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------FELVYILMSLKFNARVKVKSYTDELTPVQSAFDLYKG ADWYEREIWDMFGVYFSGHPDLRRILTDYGFEGHPFRKDFPLSGYVELRYDDEVKRVVAE PIELAQEFRKFDYNSPWEMFPAF------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------SWVDASINTQHIVAGFDQEAAAVHMARIAMFRAE TDDGPDVLRWLDRMLIRLCQKVGEYHKDDPNSFRFTEQFSLYPQFMFHLRRSPFLQVFNN SPDETSFYRHMLSREDLTQCLIMIQPILYAYSFSGPPEPVLLDTSSIQPDRILLMDTFFQ ILIYHGETIAQWRKENYQELPEYENFKQLLNAPVDDAQEILQTRFPMPRYIDTEHGGSQA RFLLSKVNPSQTHNNMYADAG--------------------------XXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXAQQPAVIHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYR KKVVLDGEEVQIDILDDYAAIRDNYFRSGEGFLCVFSITEQESFQATAEFREQILRVKSD ENIPFLLVGNKADLEDRRQVTIEEAQTRAQQWNVPYVETSAKTRANVDK----------- ---------------KLYTGLRDVVKDHLTKKVREDVLTALNNNFLQTLNNAWNDHQTSM VMIRDILMYMDRVYVQQNNVDNVYNLGLIIFRDWVVRFPTIREHLRQTLLDMVAKEKRGE VVDRGAVKNACQMLMILGIDARSVYEEDFERPFLEQSAEFYKRESQKFLEDNSASVYIKK VEARINEEAERATHYLDKSTEEPIVKVLEEELISKHMKTIVEMENSGVVHMLKNNKTEDL ACMYKLFIRVQNGLKTMSDCVSGYLKEQGKALVTEEEGGKNAITFVQSLLDLKDRFDHFL HESFNDDKLFKQMISGDFEFFININQKSPEYLSLFIDDKLKKGVKGMTEQEIENVLDKSM VLFRFLQEKDVFERYYKQHLAKRLLLNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFKD MTVSNTTME--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------IQTVAAKGESEPERKETRSKVDEDRKHEIEAAIVRIMKARKRMQHNVLVAEVTE QLKARFLPSPVVIKKRIESLIEREYLARTPEDRKIYTYVAXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXPLRVLVTGAAGQIGYALLYAVAKGDMFGPKQPISLVL LDIESMVTVLDGVVAELQDCALPLLREVIPTADVNLGFKDVDAAILVGAMPRRQGMERAD LLKANIKIFKAQGKAINQHAKRTVKVVVVGNPANTNCFICKKYAPDIPAENFSCLTRLDQ NRAQAQIAARQAVRNTIIWGNHSSTQYPDVRHATVVLEAVKDDAWINNEFIKIVQTRGGE IIRLRKLSSAMSAAKA-------------------------------------------- -----------------------------------SGTSGVLMVGPNFRVGKKIGCGNFG ELRLGKNLYNNEHVAIKLEPMKSRAPQLHLEYRFYKQLGQAEGVPQVYYFGPCGKYNALV LELLGPSLEDLFDLCDRKFSLKTVLMIAIQLISRMEYVHSKHLIYRDVKPENFLIGRQSN KKQHIIHIIDFGLAKEYIDPETHKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEAL GHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFP-ELATYLRYVRRLD FFETPDYDYLRKLFHDLMEKKGWECDWEFDWTGRQL-------VVSSTNGELAATAGHSN TPITAQAEVEVVDETKCC------------------------------------------ -------SGEIMGYIMGKAEGHTENWHGHVTALTVAPEYRRLGLAAKLMNILEEVSEKKR CFFVDLFVRVSNKVATNMYTRLGYTVYRRVLEYY-------------------------- ------------------------------------------------------------ -----------------------------------------------------QYREMYF EGGVSSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRSAHYKLTST AMLWLQTTKQGSGTMNLGGSLTRQVETDANVSDASPHIANIGRLVEDMEXKIRNTLNEIY FGKTKDIVNGLRSTKTL------------------XXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXX----------------------------SVVGMG ALCYYGMGMSNELGAIDRSTLWPPVVRERIRDTYLYFGGGLGITAISRNQRLMSLVMKNG WMAIIATMGLMIGSGMVARSIPYQEGAKQLAWMAHAGIVGAVIAPLTLMGGPLLIRAAWY TAGVVGGLSTVAVCAPSEKFLNMGGPLAIGLGLVFASSIGSMFLPPTTALGAGLYSISIY GGLVLFGFFLLYDTQRIIRKAETHPVYAAMPYDPVNASISIYLDTINIFIRIAMILSGGG GRRKMEIVYVYTKKRAEFGRQCNFSDRPAELHVDIAPDPNLTENFIERNPVDSGIQCVQE MSEHEVNTERFETDSRGVNHVEGGWPKDVNPQEVEQVIRYRKKVEKDEMYMSTIIQLAGV MEHCIKQNNAIDIYEEYFADVDADETDEPPSAKTINVFRDPNELKRTSTHISWFPDGPRK LAIAYCNLEFQGSSPDTMDSYIWDVENPNKPEMTLKPVSPLVCLEYNPKDSHVLLGGQYN GQIAYWDTRKGSQPVEMTPIEHSHRDPAYKTVWLQSKTGTECFSASSDGQVLWWDTRKLG EPTEKLYLDPTKKQDFTKSQGAMSLEYEPTMPTKFMVGTEQGSIMSCNRKAKSPGEKIVA IYPGHHGPIYALQRNPFFPKNFLSVGDWTARIWSEDIRESSVMWTKYHMAYLTDGCWSPV RPAVFFTTKMDGTLDIWDFIFKQKDPILSLQVCDEPLHSIRVQEQARLIATGSETGTTTL LELSDGLCTLQRNEKALVTAMFERETRREKILESRHREMKLKERTKSSYEELVLRINPIA NPLASRKLTKKLYKAIKKALRKGVREVQKFVRKGETGIVVFAGDTSPIDVICHMPLVCEE KEMAYCYTPSKEDLGAACGSKRPTCMVMIKAHDDYQDLYDECYGDVKSLPLPVMPAENLE EQGLEKNPKLELAQWKFLLVTDKHRNDKKLKNDLFEAIKNDNMAPFYEETCQDLGWTLDE ALLKTMKEANEAELKKLDEAVEDAEKNLGETEVRDFMIKKAEYLSRIGDKDGTVSQFRKT GEKTVTVGYRLDMAFHQIRLGLFYMDHDLITRNIEKAQSLIDQGGDWDRRNRLKVYRGAY CMAIREFKNAANYFLDTVATFTSYELMDYQSFVTYTVVCSMIALNRPDLREKVVRGSEVL EVLHSLPDVRQYLFSLYNCHYGDFFKALSKMEDMLKYDRILSAHYRFYVREMRIHAYAQL LESYSSLTLQYMAKAFGTTIDFIDQELSRFIAAGRLHAKIDKVGGIVETNRPDSKNYQYQ ATIKQGDILLNRVQKLSRVINI-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------IGLGMISPNPAFTSMVTVLGLSGIVGYHTVWGVTPALHSPLMSVTNAISGITA VGGLLLMGGGYYPTNTIQVLAASAAFISAINIFGGFIITQRMLDMFKRPTDPPEYPMLYG IPAAAFLAGYGYCANGTYLDIHQMTYLAAGLCCVGALTGLSSQGTSRIGNILGMIGVTSG IAATVGIVKPSPELLAQMVGAMGTGGLIGAIAAKRLEVTDLPQMVALFHSLVGAAAVVTC VANFMAEHSHFATDPASGVIKTALFLGTYIGGVTFTGSLVAFGKLQGVLSSAPLMLPGRH VLNASLMAGNVGAMGYYMMSDANAGLSMLGTTTALSALMGVTLTAAIGGADMPVVITVLN SYSGWALCAEGFMLNNNLMTIVGALIGSSGAILSYIMCKAMNRSLPNVILGGYGVV---- GKAKKLEGTHTEINGDQTVELMAEANDIMIVPGYGLCAAKAQYPIAEMVSLLKSKGKTVR FGVHPVAGRMPGQLNVLLAEAGVPYDIVHEMDEINDDMPDVDLTLVIGANDTVNSAAETD PESIIAGMPVIRVWLSKQVIVMKRSLGVGYAAVDNPIFFNDNTSMLLGDAKKTCDGLVTG LK-----------------TQIDQILVNQVVELLEAFVGIECQNQFAIKNIMGQTVYHAA EESGFCTRQCCGPHRGFVMHVADNMGQEVMRVTREFKCCAGCCWLACCAYEVMVESPIGV PIGYVRQSLIKPCFEVMDEVLSLSGPICICECPCC--DVNFSLYSEEIGGVQKQWTGLVK EIFTEADNFGIKFPMDLDVKVKATLMGAVFLINMMFFEKNQQXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVN RTEGLVQRRNVSSEGPDHDSKETRLTLMEEVLLLGLKDREGYTSFWNDCISSGLRGCILI ELGLRGRVELEKTGMRRRSLLNRKLLCKSDAPTGDVLLDEALKHIKESEPPQTVQSWVEY LSGETWNPLKLKYQLRNVRERLAKNLVEKGVCTTEKQNFLLFDMTTHPLTDNTIKQRLVK RVQEAVLSRWVNDATRMDKRLLSLIFLAHSSDVLENAFAPLSDEDYEVAMKRVRDLLDLD YEQMAMKDGTCDVMWCVITA---------------------------------------- KAKDQNDNRFCYMVGGLETSATSIVGQIGKFVSWRMPGSKVCNKLQKQDSQICDLRY--- ----------------------------------------------------ADDILKGF RLNWMNLRDADSGKILWQSSDDLSDPTKEHEARVPKKILKCRAVSREINFSSKEQMERFR LEQK-------------------------------------------------------- ---------------MPKVVSRSVVCTDTKDQEEYQGEKPLYVYYCLCGQMSLILDCPVD KLPMRRRDDSRVIDSNKHAHKITSEPDETIFLKRPEGIERQFRQKCKRCGLFLYYRHRNQ ITFIVDGALTKAVEMKTNVYSRMAEPKKVMVTKHTKNMGKFSSVTVSTVDEEEEELEAKE IADSYAANAKVIEKQLLRKGLSKRKLLEQAEEEAKKMRPKGTLIDLTRTCRHMAAQQQHR KYADMAFTFACPGDVRVKQVDVPSFSGSFGI----------------------------- ----XVTINEDSSVQILAEEAARIDQFDAQAVREGAAKAAQELSTEEAKAEAQIAVDCYE ALAKAVEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-FSPTDVTSEDDVKTALVAKS KYGKLDVAVNCAGIGVAIQTYNFNKDTVHPMDQYLRVLNVNAGGTFNVIRLACALIGKNQ PNADGQRGVIINTASVAAFDGQRGQAAYSASKGAIVGMTLPIARDLARQGIRVNTIAPGL FDTPLLSSLPEKVRTYLASTVPFPPKLGVPDEYAHLAQFIVESPMLNGEVIRLDGALRTR DFHFKVQGRNAESKDGISRNYPVVDHTYDAVVVGAGGAGLRAAFGLAKEGFKTACITKLF PTRSHTVAAQGGINAALGNMEEDDWKFHFYDTVKGSDWLGDQDAIQYMTEEAAQAVIELE NYGMPFSRLENGKIYQRAFGGQTLKYGKGGQAHRCCAVADRTGHSMLHTLYGRSLFYDTN YFVEYFALDLIMEQGECRGVIAICLEDGSIHRFRSKNTVLATGGYGRTYFSCTSAHTCTG DGTAMTARAGLANQDMEFVQFHPTGIYGAGCLITEGSRGEGGYLINSEGERFMERYAPNA KDLASRDVVSRAMTIEIREGRGVGPDKDHLYLQLSHLPPELLKSKLPGISETAMIFAGVD VTRDPIPVLPTVHYNMGGVPTNYRGQAVQHNGKDSIIPGLYACGEAGCASVHGANRLGAN SLLDLVIFGRSCANTIVEENKPGDAIGEVKENAGEETVANIDKLLHSEGNAPTADLRLKM QKASQTNAAVFRDGPSLKEGVTKLDAIYQEMDIKVTDKGMVWNTDLIETLELQNLMINAV QTVHAAEARTESRGAHAREDFKVRIDEYDYAKPLEGQKRN--DKHWRYHTMVNTDHTTGK TTLQYRPVIDKTLD-AKVDTIAPYIRSY--------------TVVQGLDTLKNEHHQILN SLLTSMKTIKKGDTNLVEEKTNILKKSLEMIDLGLGEAQVMMALANHLQHVEAEKQKLRA QVRRLCQENAWLRDELANTQQKLQQSEQKGATLEEEKKHLEFMNEMKKYDSEDA------ ------SAMAQAASGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHD HPDVATMLNILALVYRDQGKYKEAANLLNDALGIREKTLGPDHPAVAATLNNLAVLYGKR GKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEMYYQRALEIYV NKLGHDDPNVAKTKNNLASAYLKQGKYKQKLAGRYDTGQETECLGWIKQLTGPGMREVEK QLRNGQTLCKLAKAVKSGRMKIKFNNMSAPFKQMENIEIFLNFCQEYGVPKANQFPTVDL FEGRNMAQVMSCIQSLGSEAQRQHFNGPTCGPKPQEKHIVSFTDEQLRAGHLQAGTNKCA SQSMGSARHVADIRADDFDREGQGVLGGQMGNKGASQKGMAIGAVRHVADIRADDMDKEG QSVMGGQMGYNKGASQAGMSMGAVRHVADIRADDMDKEGQSVLGGQMGYTGGASQAGMSM GAVRHVADIRADDACEGQSVMGGQMGYTGGASQKGMSMGATRHVGDIRADDMEGQGHIGG QMGYTQGASQAGMRIGATRHVADIDGGKMSSQGVSSLQYGSNVGESQSGMSYGGR----- DSHSFGVVPVTCHAWNGDRSQIAIPNSSEVHIYKIQWTKTHVLADH-------------- ----------------------XXAATCVRWSPLENKFAVGSGDRIISICYFEEEMDFWV SKHIKKQLRSTVTSLDWHPNNVLLAAGSTDFKARVFSAYIKEVDQKPSSTAWGGKMTFGN VMGEFSSGGGWVHDVSFSASGNRLAWVGHDSSVAVVDAAVKTPFLPYVTCTWVTENSMVV AGHDCCPMLYTYDGSSVTFVSKLDEQKTTAMRHFQTLDRKAIAMKTLHQNTITQMSIYSG NKEQVTKLTSTGFDGKLINWDLKKDVEGYVGFANLPNQVYRKAVKKGFEFTMMVVGESGL GKSTLINSMFLTELYNAEYPGPSHRVKKTVDVETTNCMLKEGGVQLRLTVVDTPGFGDAV DNSNCWQPVTNFIESKYDEFLNAESRVNRRTKPDLRVHCCLYFISPNGHGLKPLDIEFMK HLHDKVNIIPLIAKADTLTPDECREFKKTILNEIAQHKIKIYEFDDDEEQRLQKKLKDRV PFAVVGSNTVVDSNGRKVRGRVYPWGVVEVENLEHNDFIALRNMLIRTHMQDLKDITNNV HYENFRFNKLSSVTKNPIAQMEEEKREHVQKMKKMEAEMEQVFEMKVKEKKQKLKDSEAD LQRRAEQMKRSLEQQQREQDDKKQQF------------MSERYSFSLTTFSPSGKLVQIE YALAAVAAGAPSVGIKATNGVVVATEKKQKSVLYDEHSV-HKVELITKNIGMVYSGMGPD YRVLVRSARKLAQQYYLMYQEQIPTAQLVQRVANVMQEYTQQGGVRPFGVSLLIAGWD-- ------------------------------------------------------------ ---------------------------------------------------ELNEAWERL KSMSLRRQDRLFGAREIQHFNRDADETIAWIAEKDIMLSTDDYGRDLASVQTLQRKHDGV ERDLAALQEKVKALSIEAERLTETHPDQADEIKNKQAEIENNWYRLSTKAHERKQHLDDS YNLHRFLSDFRDLISWIHDMKTVISADDLAKDVAGAEALLERHQEHKGEIDAREDSFKAT AEYGQQLLESDHYAVEEVKEKLVHLANEKTSLMDLWEERRILYEQCMDLQLFYRDTEQAD AWMAKQEAFLANEDLGDSLDSVEALIKKHDNFEKSLAAQEEKIKALDEFATKLIENEHYA ADDVAARRDALLQRRNALYERSTYRRRILEESYKYQMFERDCDETKIWINEKLKAATDEG YLDPTNLQGKVQKHETFEAELNANQPRIESVNTTGQELIEHEHYATDQIKERLEEIQTLW AQLKEQSDRKGSKLKEASEQQQFNRNAEDVEIWLAEIEGQLMSEDYGKDLTSVQNLQKKH ALLESDVGSRQDRIDGLTHSATCFVDCGHFDADNIKAKQVIVEERYVALKAPIENRKQKL SDAIRLQQFVRDVEDEEDWIREKEPIAASTNRGRDLIGVQNLQKKHQALQAELAGHDNHI HIVADQGKEMIEDGHFASAEINQKITALTERWQNLNDKSQQRKQDLDDSLQAQQYFADAN EAESWMREKEPIVGNTDYGKDEDSAEALLKKHEALMSDIEAYRSVIESLKEQASDCKQQE APVIDDIGKECVVALYDYTEKSPREVSMKKGDVLTLLNSSNKDWWKVEVNDRQGFVPAAY VKKIDASLSASQSNLADEFTISVRQTQIEKQYDNLKDLGSGRRDKLEESCKAYQLVREAG ELAHWINDKETIALEQEVGQDLEQVEVIQRKFDDFQKDLKANEARLVELRTVAERLTAMG QTEAAEKIKIQIEDLNKRWAALENVTQERAQSLGSAHEVQRYHRDADETKDWIDEKDEAL NTEDIGHDLATVQRLQRKHEGLERDLAALGDKVKELDETANRLMMTHPDQQTNIYDHQRE INERWNALTVKADTRKAKLLDSYDFQRFLSDFRDLMSWINSMLALVSSDELAKDMTGAEA LLERHHEHRMEIDARASTFQAFEMFGHQLLQNSHYASDDVRDKLKDLSDAREQLEEAWIA RRAKLDQCLEAQLFNRDCEQAETWMAAREASMADSADGGTPVESLIKKHEDFDRAINSQE EKISALDAFADQLINADHYDKDGISDKRDQVLERWRNLKEAMLDNRSKLGEAQTLQQFSR DADEMEIWITEKLQMATDESYKDQANIQSKHQKHQAFEAELAANSDRLGSVVSMGNKLIE GGQCAGGEDAVNERIAKLAQEWEFLTIKSTEKSEKLKTANRQRTYNAAVKDLEFWLGEVE HMLETEDYGKDLATVQNLVKKHQLLDGDVKAHDDRIKDLNEQADVFIESGMWDTDSIKEK KQTINERYERVTTLATHRRSRLEEANTLHQFFRDIDDEEAWIKEKKLLVGSDDFGRDLTG VQNLRKKHKRLEAELSSHEPAIQSVQDTGEKLMAESNLLTEEIQQRLQALNHNWEELKQM ATNRGQKLDESLSYQQFAASVEEEEAWILEKQHLLSTEDVGDTLAAVQGLLKKHEAFATD SQVHRDRCQEINKEGDKLIQEGNHNAEQIDQRCKTLQEHLEMLEEAANHRKARLIDNSAF LQFIWKTDVVESWIVDKETQVRSDDYGRDLSSVQTLLTKQETFDAGLQAFEKEGIQTITA LKEQLVASNHAQTAAIEKRYSDVITRWMKLLADSDARKQRLLRLQEQYRQVEDLYLTFAK KASAFNSWFENAEEDLTDPVRCNSVEEIRALREAHDQFKSSLSAAEADFNQLAALDKQIK AFNVGPNPYTWFTMEALDDTWRNLQKIIRERDGELQREQQRQEENDVLRKQFAQAANAFH SWLTETRSSMMEGTGTLEAQLEAKKKKSADVRSQRGQLKRIEDLGALMEERLILDNRYTE HSTVGLAQQWDQLDQLGMRMQHNLEQQIQACNTSGVSEDALREFSMMFKHFDKDKSGKLD QSEFKSCLRALGYDLPMVEEGQTDPEFETILDVVDPNRDGHVSLQEYMAFMISRETENVQ SAQDVELAFRALTTGDRPYITATELYANLTREQADYCITKMRQYEDTKSRVVPDAYDYGD FTRALFINXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIDKDDGDNPQ LVSEYVNNIYDYMRELERREVNGRMRGILIDWLVQVHLRFHLLQETLYLTVDLIDRFLE- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -GRTTGRGRRQNNPSPGPENDLERVFVWDLDETIIIFHSLLTGSYAQRYGKDPPGSVSLG LRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFQTDGFHAAATNNLCL ATGVRGGVDWMRKLAFRYRRXKEIYNSYRNNVG--------------------------- -----------RSNCVNVLVTTTQLVPALAKVLLYGIGGVFSIENIYSATKIGKESCF-- --------------------EXXXXQMNWPFWRISNHSDLAALHHALDLGYLMSALSVAG ERNTGQSVRTQNVMAASAIANIVKSSLGPVGLDKMLVDDVGDVTITNDGATILKLLEVEH PAAKVLVELAQLQDQEVGDGTTSVVIIAAELLKNADELVKQKIHPTSIIGGFRLACKEAC KYIQENLTISVDDLGRDCIINAAKTSMSSKIIGPEMDFFANMVTDAAHAIRTPDGKGGHK YPIKAVNVLKAHGQSSLESKLINGYALNCTVASQAMPKKIVGAKIAFLDFSLQKAKMHLG IQVLVEDPAKLDAIRQRESDITKERIHKILA----------------------------- -----------------LIVTLANLEGEETFEASMLGQAEEVVQERICDDELLLIKGTKA RTCASIILRGANDFMVDEMERSVHDALCVVKRVLESKTVVPGGGAVEAALSIYLENYATS LSSREQLAIAEFARSLLVIPKQLAVNAAKDSTDLVAKLRAYHNTSQTKAEHRDLKWIGLD LVEGVVRDNKKAGVFEPAISKIKSLKFATEAAITILRIDDMIKLAPEEKGGKSYQEAYQA GDLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSGGSHKERTEK YRSVLELVESLKVFIEALVNENVSLVISRQVLSDFAAKLSNLSDDLARLVSHFTLEKIQP RVISFEEQVGAIRQHLSSIYERESNWREAANVLVGIPLETAQKQYTVDYKLDTYLKIARL YLEDEDPVQAEAYINRASLLQAESKNEQLKIYYKVCYARVLDYRRKFIEAAQRYNELSYK NIIAEEERMEALKKALICTILASAGQQRSRMLATLFKDERCQQLATYAILEKMYLDRIIR SSDLQEFQAMLQQHQKAVTQDGSTILDRAVIEHNLLSASKLYNNITFEELGSLLEIPSMK AEKIASQMITEERMNGYIDQIDSIVHFEVREALPSWDKQIQS------------------ -----------MKLTDSVVRSFRVAKVFRENTERINSIDFSPNGETLISSSDDDSIVIYD CQNGTPKRTLNSKK---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------------EL NTVCALMEKDETIGCMVLTGSERAFAAGADIKEMKDQEFAVVYSNDFLGHWKGIALCKKP VIAAVNGFALGGGCELAMMCDIIYAGEKASFGQPEITIGTIPGAGGTQRLTKAIGKSKTM EMVLTGNRITAQEAEKGGMVSKVFPVDQVLDEAIKTAEKIASHSKIIVQMAKESVGASFE MSLQEGLRFEKRFFQQSFATKDRREGMTAFVEKRPPNFTD >Paravinella_sulfincola MSDRKAVIKNADMSEDMQQDAVDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSGLNTQLRQFQTSATQRDIDQAAKYIGAGAATV GVAGSGAGIGSVFGSLVIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLILFAF- ----------ETQIHRIRITLTSRNVKSLEKVCADLIAGAKDKNLKVKGPVRMPTKILRI TTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADMDQVI QYIEPAKQFAKDSIRLVKRCTKPDRREFQKIAMATAIGFAIMGFIGFFVKLIHIPINNII V----------------------------------------------------------- -----------SVVQKRFNFQEGTVELYAEKVATRGLCAIAQAESLRYKLIGGLAVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGEPCNEYVDTAVRHVLLRQ GVLGIKVKIMLPWDPSGKIGPKRPLPDNISIVEPKEEQPIAQPYSEHKGT-MSKRGRGGS SGGKFRIALALPVGAVINCADNTGAKNLYIIAVQGIKGRLNRLPAAASGDMVVATVKKGX PELRKKVIPAVVVRQRKPIRRKNGIVIYFEDNAGVIVNNKGEMKGSAINGPVAKECA--- ----------RKGRVQKVAL-PQIADGENLFGVAHIYASFNDTFVHVTDLSGKETIVRVT GGMKVKADRDEASPYAAMLAAQDVAERCKALGINALHIKLRATGGNKTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRK--------MGKPHGIRTARKMRDHRRDQRWHDKD YKKSHLGTRWKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP RDGCLNYIEENDEVLIAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKEKKERPRS--- ------RVMTNRLLSRRQMVVDVLHPGRATVPKTEIREKLARMYKTTSDVIFCFGFRTQF GGGKTTGFALIYDSLDYAKKFEPKYRLARHGARKQRKERKNRQKKVRGTKKAKVGQMPRI PLVYNKTYATPRRPFEKERLDQELKLIGEYGLRNKREVWRVKYTLAKIRKAARELLTLDE KDPRRLFEGNALLRRLVRTGVLDESKMKLDYVLGLRLEDFLERRLQTQVFKLGXAKSIHH ARVLIRQRHIRVRKQVVNIPSYIVRLDSQKHIDFSLRSPYGGGRPGRVKRKN-------- ---------------GKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVGEARDELLRMLSEDELRD AVLLVFANKXDLPNXMNAAEITDKLGLHSLRQRNWYIQATCATSGDGLYEGLDWLSNQLK NQRMPLARDLLNPSPEDEKRKCKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCSTVLCQPXGGKARLTEGCSFRRKQHMVRMNVLADALKSICNAEKRGKRQVLIRPCSKV IVRFLSVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVCIRDMEKWTTNL LPSRQFGYIVLTTSGGIMDHEEARRKHLGGKILGFFFMGRMHAPGKGISQSALPYRRSVP TWLKLTPDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKAKGLAPD LPEDLYYLIKKAVAIRKHLERNRKDKDAKFRLILVESRIHRLARYYKTKRVLPPNWRYES STASALVAVAEIPEIKLFGKWSSDDVQVSDISLTDYIAVKEKYAKYVPHSAGRYQVKRFR KSQCPIVERLACSLMMHGRNNGKKLMAMRIVKHAFEIIHLLTGENPLQVVVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGA------------------------ ---------------------------TLRGTLQGHGGWVTQIATTPQFPDIILSASRDK SLILWQLTRESRYGYPRKALRGHGHFVSDVVMSSDGQFALSGSWDGTLRLWDLGTGQTTR RFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIEDGHTEWVSCVRFSPNT QNPIIVSCGWDKLVKVWNLTNCKLKTNHFGHSGYLNCVTVSPDGSLCASGGKDGQAMLWD LNEGKHLYTLDGGDVINSLCFSPNRYWLCAASGPSIKIWDLEGKVVVDELRPEVISTSAE PPQCISLAWSADGQTLFAGYTDNLIRVWQVSMAA-MREYKLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKVVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKLARSWNCVFLETSAKSK INVNEIFYDLVRQINRKNPDPMGDDNK-SNEHINLKVTGQDGSVVHFKIKKNTPLRKLMN AYCDRTGVKSGAMRFRFDGQPINETDTPTQLDMEDGDVIDVFQQQTGGMTAMPLNPKPFL NALTGKPVMVKLKWGMEYKGYLVSVDGYMNLQLANTEEYIDGALTGNLGEVLIRCNNVLY IRGVEDDDEEGEMKDMSDAEGDDVPTA-ASGGGMDINAAIQEVLKTSLIHDGLARGLHEC AKALDXRQAHLCILANNCDEPMYVKLVEALCAEHGINLIKVDDNKKLGEWAGLCKIDKEG KARKVVGCSCVVVR--------------------MAAIRKKLVIVGDGACGKTCLLIVFS KDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSI DSPDSLENIPEKWTPEVKHFCPNVPIILVGNKRDLRNDENTKRELMKMKQEPVRPEEGRS MADKISAYAYLECSAKTKDGVREVFETATRAALQTKKKKKGKXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------KIIKPQGEEPDEFETSISQ ALLDLEMNSDLKAQLRELYITAAKEIDVQGKKAIIIFVPVPQLKAFQKIQTRLVRELEKK FSGKHVVVIAQRRILPKPTRKSKRKNKQKRPRSRTLTAVHNSILDDLCFPAEIVGKRIRI RLDGSRLIKVHLDKTQQTNVEHKLETFSAVYK----------------GRGGFRGGFGGR GRGRGRGRGRAKE-DKEWMPVTKLGRLVKDMKIKSIEEIYLFSLPIKEYEIIDHFL-PTL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDYNGHVGLGVKCSKEVATAIRGAIILAKLSI IPVRRGYWGNKIGKPHTVPCKVTGKCGSVLVRLIPAPRGTGIVSAPVPKKLLQMSGIDDC YTSARGQTATLGNFAKATYSAIANMYSYLTPDFWKENIFIKSPYQEFTDYLSR------- ------------------------------------------------------------ -----------------------------TPVAGRFTPGAFTNQFQAAFREPRLLVVTDP RIDHQPVTEASYVNIPVIAMCNTDSPLKFVDIAIPCNNKSQHSIGLMWWMLAREVLRLRG TISREVPWDVMVDLFFYRDPEEAEKE---------------------------------- -------MKFNPFVSSSRRKNRKRHFTAPSHIRRKIMSSPLSKELRQKYNVRSIPIRKDD EVQVVRGHYKGQQVGKVVQVYRKKFVIHIERIQREKANGATVPVGIHPSKVVIVKLKMDK DRKAILDRKAKSRIQGKHTEESISSPSSTRVGSTVRQRKAPASGAGAASMWKFYTEDSPG IKVGPVPVLVISLIFIAFVFMLHIWDKYNRGREKGKKKSVTNEVVTREYTINIHKRIHGI GFKKRAPRAIKAIRQFAFKQMGTEDVRIETRLNKHIWSKGIRNVPFRVRVRLARKRXEDE DSPHKLYTLVSYVPVTTFKGTQTVNVRASSKNEFLVNGKYRLVRKIGSGSFGDIYLGINV SNGEELAVKLESHKARHPQLLYESKLYKILQGGVGIPHIRWYGEKDYNVLVMDLLGPSLE DLFNFCGRRFTMKTVLMLADQMIGRIEYVHNKNFIHRDVKPDNFLMGIGRHCNKVFLIDF GLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRGS LPWQGLKAATKKQKYEKISEKKMSTPVEFLCKGYPAEFPMYLNYCRGLRFEEAPDYMYLR QLFRILFRTLNHQYDYVFDWTILKQK----MNQEKLKQRIGGKGTARRKKKVIHRTATTD DKKLQSTLKKLAVNNIPGIEEVNMIKDDGQVIHFTNPKVQASLQSNTFAINGQAETKQIT DLLPGILNQLGTESLTNLKKLAKDAADIDEDDDDVPELVENFDEASKNEMTRYSLDPENA TKSAKARGSHLRVHFKNTRETAQTIKHMHLRRAVSFLKNVKAHKECVPFRRYNGGIGRCA QAKNWKATQGRWPQKSAEFLLQLLKNAESNAEFKGLDTDHLVIEHIQVNRAPKMRRRTYR AHGRINPYMSSPCHVEVILAEREQAIAKPRKKKVSQKKLKRQKMMYREKKTGPKPELTEE QKQEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIADIDKEGTGVIDFND FLTMMTQKMSEKDSKEEILKAFRLFDDDETGKISFKNLRRVAKELGENLTDEELQEADRD GDGEINEQEFLRIMKKTSLY---------------------------------------- ---------------RALRLDTGNFSWGSEAITKKTRITDVVYNASSNELVRTKTLVKNC IVVVDATPFRQWYEAHYAMPLIKKKGAKLTEAEEELFNKRSKKTQAKYDERRKVAKIEPA LEEQFATGKLYACVASRPGRCGRCDGYILEGKELEFYSRKIKAKKGK------------- ---------KRKVPFALTAIKGVGRRYSHIILKKADVDPTKRAGELEEEEVEKVITIMSN PRQYKIPDWFLNRQKDVKDGKYSQILSNVLDSKIREDLERLKKIRAHRGLRHYWGLRVRG QHTKTTGRRGRTVGVSKKK-------------------RSSGINAEWPLRPGQSRSEKKA RKAISKLGLKQVNGVNRVTIRKSKNILFVISRPDVYKSPASDTYIVFGEAKIEDLSQQAT MVAAEKFKADEEVDETGIESKDIELVMSQANVSRSKAVKALKNNSNDIVN---MGRVRTK TVKKASRVIIEKYYTRLTLDFHTNKRICEEIAIIPSKKLRNKIAGFVTHLMKRIQKGPVR GISIKLQEEERERRDNYVPEISAIEEVDPDTKEMLKLMDMNNIP-VQVTQAITQTMKWEY KEEHPFEKRRAEGEKIRKKYPDRVPVIVEKAQKARVGDLDKKKYLVPSDLTVGQFYFLIR KRIRLRPEDALFFFVNNVIPPTSATMGALYQEHHEEDFFLYIAYSDESVYG--------- ---ICVGESGDRLTRAAKVLEQLTGQQPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAE EILERGLKVREYELRKNNFSNTGNFGFGIQEHIDLGIKYDPSIGIYGMDFYIVLGRAGFN IAYRRRKTSRIGASHRVQKEEAMKWFQQKYDGVVLPGK---------------------- ------------------------------------------------------------ ----------------IIEVGDTPKDRALFNGAQKLFGMVITVGQAIVYVMTGMYGDPAD IGAGVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVN TGRGTEFEGAIIALFHLLATRTDKVRGLREAFYRQNLPNLMNLLATVLVFAIVIYFQGFR VDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLATKFSGNFLINLLG VWADVGGGGPARSYPIGGLCYYLSPPETLSHVVEDPVHAVLYIVFMLGSCAFFSKTWIDV SGSSAKDVAKQLKDQQMVMRGHRDKSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIG SGTGILLAVTIIYQYFEIFVKEQSEMGGVSTLLFQTERAFQKQPGIFLNKKKVLLPRYVK NIGLGFKTPREAYDGTYIDKKCPFTGRISIRGRILTGVVMKMKMQRTVVIRRDYLHYVKK YNRFEKRHKNVSVHCSPCFRDIAIGDIVTVGECRPLSKTVRFNVVKVTK----------- ------------------------------------AQGKRRYDRKQAGYGGQTKPIFRK KAKTTKKIVLRMECTKCKYKKQLPIKRCKHFELGGDRKKKGQMIQYMGRVIRSQRKGAGS VFKAHTKHRRGAARLRAFDYSERHGYIKGVIRDIIHDPGRGAPLARVVFRDPYRYKLRHE NFIACEGMYTGQFIYCGKKATLQIGNILPVGVMPEGTVVCSLEEKTGDRGRLAKCSGNYA TVIS---ETKRTRVKLPSGTKKVIPSTNRACIGVVAGGGRIDKPMLKAGRAYHKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGKAST------------------------------ -AKRTKKVHITGKYGTRYGASLRKDVKKMEITQHSKYTCXFCGKDAMKRRAVGIWSCKAC KKTVAGGAYVYSTTAAAMVRSTIRRLREMKE--------YRYCKNKPYPKSRFCRGVPDP KIRIYDLGRKKARVDEFPLCVHLVSDELEQISSEALEAGRICANKYMVKNCGKDAFHLRV RVHPFHVLRINKMLSCAGADRLQTGMRGAFGKPQGTVARVRIGQALMSIRCKDQHQEKAV EALRRAKFKYPGRQKIYISRKWGFTKWDREDYEKMRLEGTLIPDGVNAKYIPPHGPLAAW MKAKRVTKILGRTGSQGQCTQVRVEFLDDTNRSIIRNVKGPVREGDILTLLESEREARRL RMTKGTSSFGKRHNKTHTLCRRCGGRCYHIQKKTCASCGYPSQRMRRYNWSEKGXRRRTQ GVGRMRHXKKVFRRFRNGFREGTVPKKV-------------------------------- ------------------------------------------------------------ -------VTLLVTLKIRFKERVTILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTAIVDNQIFCLHGGLSPSIDSLDHIKALDRIQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHTNNLTLISRAHQLVMEGYNWCHDRNVVT-SQCSHYCYRC GNQAAIMELDDALKYSFLQFDPAPRRGEPHVTRRTPDYFL-------------KQSDTMR FLLRIRCWQYRQLSNLHRAPRPSRPDKARRLGYKAKQGFVIYRVRIRRGGRKKPVPKGQV YGKPSNCGINQLKNQRSLQAIAEERVGRKCKALRVLNSYWVAQDSTYKFFEVIAVDPFHK AIRRDPTMQWICKPTAKHREMRGLTSANRKSRGLGKGHLYSKTVGGSRRAAWKRNNLMQA HRRR-------------------------------------------------------- -------------PPKCKFEPPLFHPNVYPSGTVCLSLLDEEKDWRPAVTIKQILLGIQE LLNEPNIKDPAQAEAYTIYCQNRAEYERRVREQAIRFRDPSLGKSSKMLQHINYRMRCTL QDGRTFVGTFKAFDKHMNLILGDCDEFRKVKPKAGKTREEKRPLGLVLLRGENLVSMTVE GPPPAD------------------------------------------------------ -----DIPTFKLVLVGDGGVGKTTFVKRHLTGEFEKKYIATLGVEVHPLVFHTNRGPIRF NVWDTAGQEKFGGLRDGYYIQGQCAIIMFDVTARITYKNVPNWHRDLVRVCENIPIVLCG NKVDIRDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLTGDPNLEFVAMPA LAPPEIEMDPSMAAKYEQELQIAQHTALPDEDDDLNAGIKQYYVSKVEELELIVTEKTQN LRRLEAQRNELNAKVRMLREELQLLQEQGSYVGEVVKAMDKKKVLVKVHPEGKFVVDLDK NIDITDVTPNSRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYENVGGLDKQIKEI KEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ KFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRLESGSGGDSEVQRTMLELLNQLD GFEPKQNIKVIMATNRIDILDSALLRPGRIDRKIEFPAPNEEARLDILKIHSRKMNLTRG INVRKIAEMMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFELAVAKVMQKDSEKNMSI KKLWK----------------------PIERVKLMVQNQDEMMKAGRLDKPYKGVIDCTV RTFKSEGILPFWRGNLANCIRYFPTQALNFAFKDKVKALFKLNKNDSYAIKFSKNVVSGG AAGAMSLVFVYSLDYARTRLANDAKTSKTRQFNGLLDVYKKTLKSDGIIGLYRGFVISCV GIIVYRGCYFGFYDTLKPIMLGEDAGVVTSFMLGYVVTISSGLVSYPIDTVRRRMMMTSG EAVKYKGSWDCAVKVVKTEGFMSLMKGAGANILRGVAGAGVLAGFDKFKELYVTWRAMSD MSNLDRQIENLRRCEIIKESEVKALCAKVREILVEESNVQRVDSPVTVCGDIHGQFYDLR ELFKVGGDVPDTNYLFLGDFVDRGFYSVETFLLMLALKVRYPDRITLIRGNHESRQITQV YGFYDECLRKYGSITVWRYCIEVFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRAIDRK QEVPHDGPMCDLLWSDPEETQGWGVSPRGAGYLFGSDVVQQFNTSNDISLICRAHQLVME GYKWHFNETVLTVWSAPNYCYRCGNVAAIFELDEHLKQDFKIFEAAPQEQRGKPQANYFL ------------VKNLPYKITAEEMYDIFGKYGAIRQIRVGNTAETKGTAFVVYEDIFDA KNACDHLSGFNVCNRYLVVLYYQPHKAYKKMDLQKKADELEKLKTQHGLSTPDIKMSIGV PIKVLHEAEGHVVTLETNTGETYRGKLLEAEDNMNCQMCDITCTFRDGRTAQLENVFIRG SKIRFLILPDMLKNAPMFKKVGAGRGKSAILRAAARGRGRGAGGRGGGRMQNDAGECVDM YIPRKCSASTSIIGAKDHASIQINLAEVDDTTGRMTGQYKTYAICGQIRKWEESDDCI-- -----------VRGPRKHLKRLHAPKHWMLDKLGGVFAPRPSTGPHKMRECLPLVVFLRN RLKYALTYDEVKKIVNQRLIKVDGKVRTDKTYPAGFMDVITIEKTAENFRLIYDVKGRFT IHRITSQEAKYKLCKVKKVIIGLKGVPHLVTHDGRTIRYPDPMIKVNDTVQV-------- --LFKVVLIGDSGVGKXNLLSRFTRNEFNLESKXTIGVEFATRSIQVDGKTIKAQIWDTA GQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADQNIVIMLVGNKSDL RHLRAVPTDEAKAFDKK------------------------------------------- ----------------------MSSRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVR GKDLVVLGVEKKAVAKLQEDRTVRKIALLDDHVALAFAGLTADARILINRARVECQSHKL TVEDPVTLEYITRFIAQLKQRYTQSNGRRPFGLSTLIIGFDGTPRLYQTDPSGTYHEWKA NAIGRSAKTVREYLEKHYTTE--------------------------------------- ---------------------------GS-SGGDKKDDKDKKKKYEPPVPTRVGKKKKKL KGPDAANKLPLVTPHTRCRLKLLKLERIKDYLLLEEEFINNQERLKPQEEKQEEERSKVD DLRGTPMSVGSLEEIIDDNHAIVSTSVGSEHYVNILSFVDKDQLEPGCSVLLNHKVHAVV GVLSDDTDPMVTVMKLEKAPQETYADIGGLDQQIQEIKESVELPLTHPEYYEEMGIKPPK GVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPA IIFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPA LIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTLADDVNLEDYIMAKDDLSGADIKAICT EAGLLALRERRMKVTNEDFKKAKENVLYRKNEGTPEGLYL-------------------- ----------------------------------------------------------TV TNKMAPALRKVYDQMPDPRWVISMGSCANGGGYYHYSYSVVRGCDRIIPVDIYVPGCPPS AEALLYGVLQLQKKIKRWNSMQMWYRRTDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYA NNSNYKNDTIIRKEAYVHKSVMDELKRIIEESEIMQEDDNLWPPPDRVGRQELEIVIGDE HISFTTSKIGSLVDVKGSKDPEGLRTFYYLVQDLKCLVFSLIGLHFKIKPI--------- ----------------------------LRQGKAKLVIIANNTPPLRKSEIEYYAMLAKT GVHHYNGNNIELGTACGKYFRVTTLSITDPGDSDIIRSMPSGXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKIELCT FSGYKIYPGHGKKLVKIDGRGYLFLSAKCEKSHQMKRNPRKINWTVLYRRKHKKGQTEEV SKKRTRRTTKFQRAITGATLTDILAKRNQKPEVRKAQREQAIRAAKEKQKAKE------- ---MKLNISYPATGCQKLIEVDDEHKLRAFYEKRMATEMPADTLGEEWKGYIVRISGGND KQGFPMKQGVLTAGRVRLLLKKGHSCFRPRRSGERRRKSVRGCIVDANLSVLNLVIVRKG VNDIPGLTDTTIPRRLGPKRASKIRKLFNLSKEDDVRQYVVRRPLPPKTKA--------- -----------------------------------------------------KVKAKDL RGKKKDELQKQLDELKHELAQLRVAKVTGGNASKLSKIVVVRKSIARVMTVMHQTQKANL RKFYKPKDLRPKKTRAMRKALTKHERSLKTAKQRRKERSFPLRKYALK-----PKVTEKV YFDIEIGGEKAGRIVIGLFGKTVPKTVKNFATLAAGTQTYKGSKFHRVIKDFMIQGGDFT KGDGTGGKSIYFEDENFKLKHYGAGWLSMANAGKNTNGSQFFITTKATPWLDGRHVVFGK VLEGMKVVRKIESISTDRDRPEKDVVIADCGVIEVETPFAVDKAAAEEKRAKLELKFTVD CSHPVEDGILDCSSFEKFLQERIKVAGKTNNFKSKITVVSEIPFSKRYLKYLTKKYLKKH NLRDWLRVVANNKDSYELRYFQINNEEEEEDEDNNKEDK-EDDTKYGSCEGPDAMYVKLV SSDGHEFIVKRDHALTSGTIKAMLSGPGQFAENETNEINFREIPSHVLQKVCMYFTYKVR YTNSSTEIPEFPIAPEIALELLMAANFLDC-----LEEVKKHNTAKDLWFAIHDKVYDVT KFIEEHPGGEEVLLEQAGGFATESFEDVGHSTDARELMKTYEIGELAEADRNMLMSWLVP LVIAVGTAMAYRYFMSYMLQHLHNGWQVDQAILSEEDRVVIIRFGHDWDPTCMVMDETLY RIAEKVKNFAVVYLVDISEVPDFNKMYELYDPCTVMFFYRNKHIMIDLGTGNNNKINWAM EDEQEFIDIVETVFRGARKGRGLVVSPKDYSTKYRYKKLQKQLEFLEVQEEYIKDEQKNL KKEYLHAQEEVKRIQSVPLVIGQFLEAVDQNTGIVGSTTGSNYYVRILSTIDRELLKPSA SVALHKHSNALVDVLPPEADSSITMLQADEKPDVTYADIGGMDIQKQEVREAVELPLTHM ELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVR DVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTVNVKVI MATNRADTLDPALLRPGRLDRKIEFPMPDRRQKRLIFATITNKMNLSEDVDLDDYVARPD KITGADINAICQEAGMQAVRENRYVVLPKDFEKGYKNNIKKDEMEHEFYKCHPPLTVDSV RDRVMLVLKLYDKINPEKLTVDSHFMNDLGLDSLDQVEIIMAMEDEFGFEIPDADAERLM RPSDIVQYIADKEDL--------------------------------------------- FEKPSAIQQRAIRPIIKGRDVIAQAQSGTGKTATFAISILQCLDTTVRETQALVLSPTRE LAVQIQKVVLALGDYMNVQCHACIGGTSIGEDIRKLDYGQHVVSGTPGRVFDMIRRRNLR TRSIKILVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLVSATLVHEILEMTSKFMTDPI RILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKM RDANFTVSSMHGDMPQKERDTIMKEFRSGSSRVLISTDVWARGLDVQQVSLVINYDLPNN RELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVGDLI------ ------------------------------------------------------------ --------------SLVQTTDFFYPLVDDPYMMGKIACSNVLSDLYAMGVTECDNMLMLL AISQKLTDKERDVVAPLMIRGFKDCAEEAGTSVNGGQTVVNPWMTIGGVATTVCQPNEFI MPDNAVVGDVLVLTKPLGTQVAVNAYQWLDQPERWNRIKLVVSEDDVRKAYQRAMFSMAR LNRTGAHLMHKYNAHGATDVTGFGLLGHANNLARIQKNEVGFVIHNLPIIAKMAAVSKAC GNMFGLLQGHSAETSGGLLIALPREQAAAFCKDIEKQEGYQAWIIGIVEXGTRSARIIDK PRVIEVPAKGKR------------------------------------------------ ----------------------------------------MSTMTPKIVMFSMDIGEKPK ASQNKLEEMINELSVSLTGVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMT LGQVYYLKRFFEVRRVV------PYLTAVRHTLTAAXCLENFSSQVVERHNKPEVEVRXS KELLLTPVYISEMRK--------------------------------------------- ------------------------------------------------------------ -----SRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLV TMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTVPNTFKTLDSWRDEFLIQAGPRDPEH FPFVVIGNKIDLENRAVSTKRAQQWCQSKGDIPYFETSAKEAINVEQAFQTVAKNALAQE TEVELYNEFPDQIRLTNDQNESSCGCTFPFDARFPNQNQTRACWQNYVDYHRCLKIEDYG PCNYFKRIFTSMCPNEWIEKWDEQVEKGILLAR--------------------------- --------------YSQSIKQTEDDIQNIMKRVNELTGIKESDTGLAPPALWDLAADKQT LQNEQPLQVARCTKIINADSDDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNK YQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGI EPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMART KKACIIFFDEIDAVGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDT LDPALTRPGRLDRKVEFGLPDLEGRALIFKIHARSMSVEKDIRYELLARLCPNSTGAEIR SVCTEAGMFAIRARRKMATEKDFLEAINKVIKAYAKFSSTPRYMTYNMGQEKIHINIVVI GHVDSGKSTTTGHLIYKCGGIDKRAIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITI DIALWKFETKNYYVTVIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQT REHALLAFTLGVKQLIVGVNKMDSTEPPYSEARYLEIKKEVSAYIKKIGYNPDTVAFVPI SGWHGDNMMNMPWFKNWEVVTGTTLLEALDAIDPPSRPTDKPLRLPLQDVYKIGGIGTVP VGRVETGVLKPGMVVTFAPVNITTEVKSVEMHHNALEKAEPGDNVGFNVKNVSVKDIRRG NVCGDSKNDPPKAIEKFKAQVIILNHPGQIQAGYAPVVDCHTAHIACKFAELLKKIDRRS GKELEDNPPHVKSGDAAIVEMVPSKPMCCEAFSDYPPLGRFAVRDMKQTVAVGVIKSVVR KEGVGGKVTKAAQKAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSYAYLF KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES FRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSSSNMVIMLIGNKSDLEARR DVKKEEGEAFAREHGLIFMETSAKTAANVEEAFINTAKEIYQKIQDGVFDINNEANGIKI GPQHSMTNPSSSGGGNQSSGMTRGRIDLGDVTVHNIKQLKRLNQVVFPVAYNDKFYKDVL EVGELAKLAYFNDIVVGAVCCREDKSDGRRRLYIMTLGCLAPYRRLGIGSKMLEHVLKIC EKDGNYDNVYLHVQVNNEDAVKFYEHFGFEIVERNENYYKRIEPADAYVLQKTFKKMPRQ IMEIKDFLLTARRPDAKSVKIKXNVKFKVRCSRYLYTLVIHDTEKAEKLKQSLPPGLSVK ELK------------------KKRKFTETVELQISLKNYDPQKDKRFAGTVKLKHIPRPK MKVCVLGDQQHCDEAKANDIPYMDVEALKKLNKNKKLVKKLAKKYDAFIASDSLIKQIPR IVGPGLNKAGKFPTMLTHTDSMISKVNEVKATIRFQMKKVLCLAVAV------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------GFYDECKRRYN IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLQAGRPVTPPRGSAKNK GKM--------------------------------------------------------- ------------------------------------------------------------ ----------------------TRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDEL PAEFKLYLPVQQKMTDNTIQNLQDPFADDEGIHIRIQQRNGRKTLTTVQGISSEFDLKKI VKVAKKEFACNGTVVEHPEYGEVIQLQGDQRQRISQFLKKVGLEEQIKVHGFSAIFNFQS LLTVVLLLICTCAYVRAIAPRLLDKNKEGLLGIFWKCARIGERKSPYVAVCCVVMAIRIL FLTSGRLVTTLARQLPRAASKRKSLGATFVGCRNISTTSEVSSILEERILGGMSADLEET GRVLSIGDGIARVYGLKNIQAEEMVEFSSGLKGMALNLEPDNVGIVVFGNDKLIKEGDVV KRTGAIVDVPVGMELLGRVVDALGNPIDGKGPLNSSKRARVGTKAPGIIPRISVREPMQS GIKAVDSLVPIGRGQRELIIGDRQTGKTAVAIDTIINQKRFNDGQDEKAKLYCIYVAIGQ KRSTVAQIVKRLTDTNSMRYTIVVSATASDAAPLQYLAPYSGCAMGEYFRDNGKHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDDFGGGSLTALPVIE TQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTKAMKQVAG SMKLELAQYREVAAFAQFGSDLDAATQQLLNRGVRLTELLKQGQYVPMAIEEQVAVIYAG VRGHLDKVDPARITTFEKEFLAHMLSSQQDLLETIRKDGQIKPETDAK------------ MESVYRLPYTVLLCPNLKLKRPSWVRQPSAMVMFAIVLTSYFLVTGGVIYDVIVEPPSIG STTDEKGNSKPVAFMPYRVNGQYIMEGLASSFLFTLGGLGFVILDQTNKPSTPRLNRILL LSVGFISILISFFMCRVFMRMKLPMPKVRRSRKPPPEGWELIEPTLDELDQKMREAETET HEGKRKVESLWPIFRIHHQKSRYIYELFYKRKAISRELYEYCLKENIADKNLIAKWKKQG YENLCCLRCIQTRDTNFGANCVCRVPKPKLQEGKIVECVNCGCRGCSGEYAQVLKMLGNG RLEAMCFDGTKRLCHIRGKLRKKVWINTSDIILIGLRDYQDTKADVILKYTADEARNLKV YGELPESAKINEDEECNVCFDDIDEILVRFLMKLSHETVTIELKNGTQVHGTITGVDVSM NTHLKSVKMTVKNKDPVQLESLSIRGNNIRYFILPDSLPLDNLLIDDTPRAKARK-TSQK PKTEMTPEELAAREQEEFNTGPLSVLTQSVKNNTQVLINCRNNKKLIGRVKAFDRHCNMV LEEVKEMWTEVPKTGKGKKKSKPVNKDRYISKMFLRGDSVILVLRNPLPIVIDARGHLLG RLAAVVAKTILQGQRVVVVRCEGINISGSFYRNKLKYLSFLRKRMNTNPSRGPYHFRAPS KIFWRTVRGMLPHKLTRGKQALDRLKVFEGIPPPYDKQKRMVVPSALKVLRLKSRRKSCV LGRLSHEVGWKYQNVITTLENKRKLKSTRYYERKKQENKLREQAMRIKPYQQVIEGYGYP GDPEKGKKIFVTRCAQCHTVEAGGKHKTGPNLHGFIGRKTGQASGYNFTEANMNKGIVWS RETLNTYLENPKKYIPGTKMIFAGLKKKNDRADLIAYLEQASK-----TVAVIKPDAYKD EIMNKIREAGFHIAARKETELTREIAEQFYKDQKDKDYFSDLTEHMSSGPTLFMVLSRED AVEGWRSMMGPTDPEKAKEENPETLRAQFGSDIKANAIHGSSSEIHAQESMKLIFGDLKF NP-------------------MKGLTELCKKKPEDPVIWLADWLLSNNPNKPKVKMFEAR LVQGSLLKKVLEAIKDLLNEATWDCNSTGMSLQAMDSSHVSLVSLQLRSDGFDTYRCDRN LSLGINLSSMSKILKCASNDDAITIKAGDDADTVTYMFESPNGEKVSDYEMKLMDLDTEH LGIPETDYSCVIKMPSAEFQRICRDLSQIGESVVICCTKEGVKFSASGDLGTGNIKLAQT ANVDKEEEAVIIEMQEAVTLTFALRYLNFFTKATPLSSQVSLSMSADVPLVVEYKIGDMG YVRYYLAPKIEDSDETRCTAAYQTTSRAAKGKVVAVIGAVVDVQFEDGLPAILNALQVTD RTPKLILEVAQHLGENTVRTIAMDGTEGLVRGQECVDTGSSIRIPVGPETLGRIMNVIGD PIDERGPIESNAFASIHAEAPAFVEMSLEQEILETGIKVIDMLAPYAKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIEGGVISLKDKTSKVSLVYG QMNEPPGARARVALTGLTVAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIA ELGIYPAVDPLDSTSRILDPNVVGQEHYEVARGVQKILQDYKSLQDIIAILGMDELSEDD KLTVARARKIQRFLSQPFQVAEVFTGSAGKLVPLKDTIRGFKEILNGTYDHLPEVAFYMV GGIEEVAQKADRLAEERMLMPKKNRVAIYELLFKEGVMVAKKDYYAPKHPELDVPNLQVI KAMQSLKSRGLVNEQFAWRHYYWYLTNEGIQYLRDFLHLPPEIVPATLKRQQGGEDRAAY RRAGGPDKKADVGAGS----------------------------------YVRNCPSGHT LSEEFKKYYGN-FSYGDASKFAEHVFRTFDTNSDGTIDXREFICALSVTSRGKLEQKLKW AFSMYDLDGNGYISRQEMLEIVSAIYKMVGSVMKMPEDESTPEKRTDKIFRQMDTDLDGK LSLEEFIEGARSDPSIVRLLQCDPMSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNL TGLNEQVPHYRQALDMILDLEPDDELEENPNQSDLIEQAAEMLYGLIHARYIMTNRGIAQ MIEKWQQGDFGHCPRVYCENQAMLPIGLSDVPGEAMVKLYCPKCQDVYTPKSTRHHHTDG AYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPVAYELQYQSAANFKTGYVN-KR MTNTKGYRRGTRDLFSRPFRKKGVIPLSTYMKVYKVGDIVDIKGNGAVQKGMPYKYYHGK TGRVYNVTQHAVGVIVNKRVGGRIIPKRINLRIEHVKHSKCRQEFLNRVKDNEKRKAEGK KIIDCKRKP---------------------------------FKQVHPEEGKLEWKEMTD RAANTAFMIELSKGLGIVMSHLFKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAICPAQAITIEAETRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEY STETHEELIYNKE----NGDRWEPEIAGNLQADYLYRMASTAKVAKTDSKNNHETDKEQQ EAIEKIDEVQNEIDKLNEQASEEILKVEQKYNKLRQPYFGKRSELIAKIPNFWVTAFVNH PQVSALL----------------------------------------------------- ---------------------------FQWFIDNVDPSADDIAEVIKDDMWPNPLQYFLA PDIEENGYDGEGLQVIGKKLTREEELLLQDFSRNVSTKSNALFYGNAFIVSAIPIWLFWR IHQMEPLIVFGIGTIISTWFVAFAYRNVKFFLKHKIALKRGEAVSREVMKKVADDKKMS- QEKEERILWKKNEVADYEATTFSIFYNNALYLMLVIIVSFYILRSFSPTFNYIGSVGSAA GLLALFSTST-------------------------------------------------- ------------------ERFTGLGSFYCRNAGAVILAYDLTDEDSFHSLRARFLPLIRA AEPNCLVVVVGMKQDLRAVEQKEALMLAKEDKIPYYEASSVSGHNVENVF---------- ------------------------------------------------------------ -----------------------------FSELEDKYGEIEEMNVCDNLGDHLVGNVYVK FRYEEDAEKAVADLNNRWFNSRPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKP ISRELRRELYGRSRRSRSRSRDRRRSRSRDR----HRSRSRERS-MFLTRSEYDRGVNTF SPEGRLFQVEYAIEAIKLGSTAIGIQTAEGVVLAVEKRVTSPLIEPNSIEKILEVDSHIA CAMSGLIADSRTLIDRARVEAQNHWFTYNEKMSIESVTQAVSNLALQFGDDDAGPGAMSR PFGVALLFAGIDEKGPRLFHMDPSGTFLQYEAKAIGSGSEGAQQALQEVYHKSMTLKEAC KESLKILKQIMEEKLNETNVEMATVTKDKLFHMLSKEEIEEFIKDIAQKTWEMSNNVETI SSIDDIYRYDKKQQQDMLTTKPWEKDAHFFKNIKISALALLKMVMHARSGGNLEVMGLLL GKVEGNTMIVMDCFALPVEGTETRVNAQAQAYEYMAAYTESAKQVKRLENAIGWYHSHPG YGCWLSGIDVGTQMTNQQFQEPFVAIVIDPVRTISAGKVNLGAFRTYPKGYQPADDGPSE YQSIPLNKIEDFGVHCKQYYALDVSYFKSALDRKLLESLWNKYWVNTLSSSSLLTNSDYT TGQIIDLSDKLEQSEAQLGRGGFMEKKSEDKLAKATKDGCKNTIEAIHGLMSQVLKDKLF NQVGNLPRRIIKETQRLNXEPVPGIEACPDESNARYFHVIVMGPKDSPYEGGVFKLELFL PEEYPMSAPKVRFMTRIYHPNIDKLGRICLDILKEKWSPALQIRTVLLSIQALLSAPNPE DPLANDVAEQWKINEVQAIETARKWTRQYA------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------LLDALEF NQVIXFVKSVPRCVALCQLLVEQNFPAIAIHRAMSQEDRLSRYQQFKDFQKRILVATNLF GRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITXVSDETDAKV-------- ----------------------------------------------------------TF TEKWNTDNTLATEITIEDQLLKGLKLSFDTQFAPQTGKKSGKIKTSYKQEYINVNCDVDF DFAGPTINGAAVVGYSGWLAGYQFAFDKSKLSRSNFAVGYSTDDFTLHTSVNDGTEFNGS LFQRVNDELETGVQLKWAAGSNATSFGIAAKYCPDKDSTYRAKVNNNSQIGLSYQQKLRD GVSVTLSTSIEGKNFSQGGHKVGLGIDFEAQSTREKALQDYRKKLLEHKELEARLKEMRE QQKELNKQYDKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQIDKSK LRQGTRVALDMTTLTIMRYLPREVDPLVYNMSTEDPGSVSYSEIGGLSEQIRELREVIEL PLLNPELFQRVGITPPKGCLLFGPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIGES ARLIREMFGYARDHQPCIIFMDEIDAIRRFSEGTSADREIQRTLMELLNQMDGFDALGQV KMIMATNRPDTLDPALLRPGRLDRKIEISLPNEQARLEILKIHASPIAKHGEIDWEXIVK LSDDFNGADLR--CTRTGMFAIRAERDYVIEEDFMKALLEKSDNKKLESKLDYKPVMPEN LKTVIGRFYNEYVSSTPTKLKLIDAYLGYILMTGVIQFIYCCIVGTFPFNSFLSGFISCV GSFVLAACLRVQVNPQNKSEFGNISPERAFADFVFAHIILHLVIINFIGSLASPSQLLPL ELVDKCIGSKIHIIMKSDKEIVGTLLGFDDFVNMVLEDVVEFENTPEGRRVTKLDQILLN GNNITMLVPGSEGPEVIDHYENPRNVGTLDKNDKSVGTGLVGAPACGDVMKLQIKVDKDG KIVDAKFKTFXCGSAIASSSLAT------------------------------------- ---------------MLVLVLGDMHIPHRTSQMPSKFKRLLVPGKIQHILCTGNLCTKES FDYLKTLASDVHVVRGDFDENLNYPEQKVVTVGQFRIGLCHGHQVVPWGDTESLAMLQRQ LDVDIMITGHTHKFEAFEHENRFYINPGSATGAFNPLDMNIIPSFVLLDIQQSTVVAYVY QLVGDEVKVERIEYKKMGKFMKAGKVVLVLSGRYAGRKAVIVKNYDDGTPDKPYGHALVA GIDRYPRIVTKKMGKKKIKKRSKIKAFVKVYNFNHLMPTRYSVVNLEKSVINKDAFRDPA LRRKARREAKMKFEERYKTGKNKWFFQKLRF--------------GRGGEIIKRFEQKGF KLVAMKFMWASEEHLKKHYADLAGKPFFPKLIKYMSSGPVVPMVWEGNVVKTGRKMLGET NPFDSLPGTIRGDFCIEVGRNICHGSDSVESAEKEISLWFNKDEQITWTPCDEDWVYEGE VPKPIKTPAKAKEKALKAKKAVRLGIHEKRHKKIRTSVHFHRPRTLRLRRLPKYPQNSTP RRPRLDKYKIVKYPLTTESAMKKIEDNNTLVFIVDKRANKHLIKIAVKQLYDIDVSKVNT LIR---EKKAYVRLAPDYDALDVASKIGIIMASKQRMRVANDKHSKNVLNRGNVPKTLKQ TEEKTPVGPWLLGLFVFVVCGSAVFQIIQSIRMVKVKSWTAVATWRWVANDENCGICRMP FDGCCPDCKLPGDDCPLVWGQCTHCYHIHCIVKWLNSQPDRQLCPMCRREWKYK-MIRFI LIQNRAGKTRLAKWYMHFDDEEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIVYRRYAGL YFCICVDITDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYSIVDEMFLAGEIRE TSQTRVLKQLLMLSSLEEDTIFGKIVRGEIPTKFIYEDDKAVAFHDINPQAPVHFLVLPK KPIQQLSNDSALLGHLLTVVRKVAVKDDGYRVVINDGKNGAQSVYHLHIHVMGGRQMGWP PMGGLFSYFANLFGSKERRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVQYKN LKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSMDRDRIGISKQELVSMLEEEELKKAT LCVFANKQDIEGALTVTEVANALGLSSIKNRKYQIFKTSAIKGEGLDEAMEWLANALQNT K----------------------------------------------------------- -------------------AGEHVICLHSNSSAWFGGGQLRVHLDIQVGEHANDYQQIAA KDKLTELQLRVRQLLDQVEQITKEQNYQRYREERFRQTSESTNQRVLWWSIGQTVILLLT GFWQMKHLKSFFEAKKLVMFYHVSLEHEILLHPKYFGPNLLDIVKQKLFTEVEGTCTGKY GFVVAVTIIDDIGAGLIQPSRGFVVYPVKYKAIVFRPFKGEVLEAVVTQVNKVGIFTEIG PLSCFISRHSIPPDMEFDPNSNPPCYKT-----------QIKLKIVGTRVDATDIFAIGT LLDDYLGL--RLYVKATFTGFKRGLRNQHENTALLKIEGVTSRKETEFYLGKRCAYVYKA KNKTTCPGHDKPSRLRVIWGKVTRPHGNSGAVRAKFRRNLPPAAMGKRIRVMLYMAKKTY DLLFKLLLIGDSGVGKTCLLFRFSDDAFNTTFISTIGIDFKIKTVELDGKKIKLQIWDTA GQERFHTITTSYYRGAMGIMLVYDITNAKTFENISKWLRNIDEHANEDVEKMILGNKCDM EDKRQVPTSKGEQIAHEHGIPFLETSAKSNINVERAFMDLAQAILNK------------- ------------------------------------------------------------ ------------------------------NMIKQKRKEKAGKWEVPLPKVRGVSEKEMF RVVKTGKSKRKGWKRMVTKVTYVGEGFTRKPPKYERFIRPMALRFKKAHVTHPELKATFC LPII-------------------------------------------------------- -----------------------------------APIRPDVVTFVHSEMRKNSRQPYAV SAKAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRR INLNQRRYAMTSAIAATGIPALVMSKGHRIEETPEVPLVISDSLEEIKKTKQAVGVLRKF KAWSDIEKVKKSRRFRAGKGKMRNRRRIQRRGPLIIYNQDNGITRAFRNIPGVTLLHVDR LNLLKIAPGGHVGRFCIWTESAF-QLDSIYGTWKSASVAKKNYNLPMPIMTNSDLSRLLK SEEIQNSLRAPVKHQKGRKLKRNPLKNAAAMNKLNPYASAQKKMAKHKQDRQKLLDAKRG IAT--------------------------------------------------------- ------------------------------------------------------------ -------------QRSQIAIPRSGYDRIPETLTDLLDEFGTDDHEGQGDLPEARSMRXRN KMFYFDVGQNRRGVFMRVSESNFRTXITIPERSWAEFRDILTEFVDKQERKQRDAQMRAS INQKLVESGERERLMELLRTRLIECGWRDQLKAYCKEIVRQKGLEHVTVDDLVNEITPKG RALVPDQVKKELLQR----------MNIRNARPDDLMNMQHCNLLCLPENYQMKYYFYHG LSWPQLSYVAEDVKGKIVGYVLAKMEEDPEDSVPHGHITSLAVKRSHRRLGLAQKLMDQA SRAMVECFGAKYVSLHVRKSNRAALHLYKNTLKFDIYEIEPKYYADGEDAYAMRRDLSEF IEKYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMAEEVVEKKTEETKR VVHTYPLIRHSDMNEEMRTEAMELCVTACEKFSNNNENAAKMIKETMDKKF--------- -------------------------------MSHRKFSAPRHGSLGFLPKKRSRRHRGKV KAFPKDDRNKPIHLTAFLGYKAGMTHIVRDVDRPGSKVNKKEVVEPVTIIEAPPMMIVGV VGYIETPRGLRTFKTLFAEHLSDECKRRFYKNWYKCKKKAFTKACKKYQDELGKKEIQKD LTKMKKYCTVIRVIAHTQMKMLKKRQKKAHIMEIQVNGGTISEKVDWAYEHFEKPVQISE VFCQDEMIDIIGVTKGKGFKGVTSRWHPKKLPRKTHKGLRKVACIGAWHPARVAFSVARA GQKGYHHRTEMNKKIYRIGQGIHMKDGKLVKNNASTEFDVTEKTITPMGGFPHYG----- FVMIKGCCVGPKKRVLTLRKSLLVHTKRRALEKITLKFIDTSSKFGHGRFQTRKEKQTFM G-----MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLG LWDTAGQEDYDRLRPLSYPQTD-------------------------------------- ------------------------------------------------------------ ------------------IFDPSLKKKKKKKMPFDVDAVLEDITLDDSLSKKKKKKKKPF DLSELEEVLPKKEESLPSKKKKQDTDRDYSYDELLNRVFSIMREKNPDMVAGEKKKFVMK PPQVMRVGTKKTSFSNFSEICKMLHRQPKHLLQFLLAELGTSGSIDGNNQLIIKGRFQQK QIESVLRRYIKEYVTCHTCRSPETILQKDTRLYFLQCETCSSRCSVASIKSGFQAVTGKR AAIRAKTSFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGK DYSLHRLILGTHTSDEQNHLLIASVQLPNDNAQFDASHYDSEKGEFGGFGSVSGKIEIEI KINHEGEVNRARYMPQNPCVIATKTPSSDVLVFDYTKHPSKPDPSGECHPELRLKGHQKE GYGLSWNPNMNGHLLSASDDHTICLWDINTTPKENRCIDAHTVFTGHTSVVEDVSWHLLH ESLFGSVADDQKLMIWDTRSSNTGKPSHAIDAHTAEVNCLSFNPYSEYILATGSADKTVA LWDLRNLKLKLHSFESHRDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQSAEDA EDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEEPDTPAS ELEMPTSSTARVYADVNTHRPREYWDYEAHTVEWGQQDDYQVVRKLGRGKYSEVFEAINI TNNEKCVIKILKPVKKKKIKREIKILENLRGGTNVIALLAIVKDPVSRTPALIFEHVNNT DFKQLYQTLTDYDIRYYMFELLKALDFCHSMGIMHRDVKPHNVMIDHETRSLRLIDWGLA EFYHPGQDYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPFFHGHDNY DQLVRIAKVLGTEELFEYIDKYQMDLDGRFNNILGRHSRKRWERFVHSENQHLVSPEALD FLDKLLRYDHQERLTAREAMDHPYFFPIVKE----------------------------- -----------------------------PEEKIAFVIRIRGINGIHPRPRKVMKLLRLL QINNGTFVRLNKATLHMLRIADPYVTWGYPNLKSVRELIYKRGYGRIEGRRIALTDNELI EKKLGRYGIICIEDLIHEIYTCGPHFKQANSFLWTFKLNTPTGGWVKKNNHFVDGGDFGN RENKINVLLRKMMQFMLLFSRQGKLRLQKWYIAHPDRLKKKITRELITMILARKPKMCSF LEWKDLKIVYKRYASLYFCCCVEASDNELLTLEIIHRYVELLDKYFGSVCELDIIFNFEK AYFMLDELLIGGEVQETSKKNVLKAIAAQDLLQEETPQGFFEDHGLGMSKAHPPELKKYM DKKLQLRLNGSRTVVGVLRGFDPFMNIVIDEAVEETKTGQKNSIGMVVIRGNSIVLLEAL ERIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXMAIRYQMAVGLNKGHKVTTLKPRPSRRKGTLTKHAKFVRDLVK EITGQCPYEKRTVELLRISKDKRALKFCKKRLGSHIRAKRKREEMASVIQQMRKA----- ------------------------------------------------------------ --------------------IPVTYPATAPEIALPELDGKTAKMYRGGKICMTDHFKPLW ARNVPKFGIAHAMALGLGPWLAVEIPDLISKDIIKHKEDLTDFQFLGELRRMNKRQLYYQ FLNFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFYRGDLLFLTNYEEEPVRVGE IVVFKIEGRDIPIVHRVLKVHEKDNGTVKFLTKGDNNQVDDRGLYAPGQMWLNKSDVVGR ARGYVPYVGIVTILMNDYPKFKYAILALLGLFVLIHRE----NPEYDYLFKLLLIGDSGV GKSCLLLRFADDTYTDSYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYR GAHGIIVVYDVTDQESFNNVKQWLKEIERYASENVNKLLVGNKCDLTSKKVVDYTTAKEF GDQHGFPFLETSAKNSTNVEQAFMTMAAEIKNRMGPMPATTSVNINSSTPVKPSGG---E ESLGEEVLRMSTDEIISRTRLLDNEIKIMRSDIMRITHEVQSQKDKIRENTEKIKVNKTL PYLVSNVIELLDVDPQDQAEEDGAHVDLDSQRKGKCAVIKTSTRQTYFLPVVGLVDAEEL KPGDLVGVNKDSYLILETLPQEFDSRVKAMEVDERPTEQYGDIGGLDKQIQELIEAVVLP MTHKERFEALGIQPPKGVLLYGPPGTGKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGA KLVRDAFALAKEKAPAIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNQD IKVIAATNRVDILDPALLRSGRLDRKIEFPTPTEEARARIMQIHSRKMNVSPDVNYEELA RCTDDFNGAQCKAVCVEAGMIALRRGATELTHEDYMDAILEVNAKKKANLNYYA------ ------------------------------------------------------------ -------RTYGEGLWNSLIGFILVYSVTDRRSLAAIDQMTSYIRYVKRDRYLWVLVGDKM DASVDRCISKEEGRQVAFDLGVSFYETSTRTTSHVTKIFHDLVQIRCVSVRRELD----- -----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXQGPGFVGIKFCQECNNMLYPKEDKENTRLLYACRNCDYQQE ADNPCIYVNKIQHDVDELTQIIGDVIADPTLPRTEDHPCPQCGHKEAVFFQSQSRRADEG MRLYYVCTEPHCMNRWTERPPYKVADISLADWGRKEIEIAENEMPGLMMMRKIYGPKKPL KGARIAGCLHMTVQTAVLIETLKELGAELRWSSCNIFSTQDHAAAAMAKSGIPVFAWKGE TDEEYLWCIEQTLVFDDGQPLTMIVDDGGDLTNLVHEKYPQYLSGLKGLSEETTTGVSNL YKRLAKGTLKVPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGKVVTVAGYGDV GKGCCHALRAFGARVIVTEVDPINALQAAMEGYEVTTLEETLGEARLFVTTTGCKNIITG KHFSNMLEDTIVCNIGHFDCEIDVKWLNENCVSKDTIKPQVDRYTLKNGRHIILLAEGRL VNLGCAMGHPSFVMSNSFTNQVLAQIELWTKSDKYKVGVYFLPKKLDEEVAAAHLEHLGV KLTKLTDEQAEYLGVPKEGPFKPDHYRY------------------------ERIYVKMR NDRELRGRLHAYDQHLNMILGDVEETVTTLEIDEETYEEIYKTAKRTIPMLFVRGDGVIL VSPPMRTMSTSNVENLPPQVIRHVAKELAELQKEPPEGVKVFPNEDDITDIQAAIDGPSG TPYAGGYFKIKLVLGKNFPREPPKGFFITKIFHPNVAKNGEICVNTLKRDWKTDYGLKHI LLTIKCLLIVPNAESALNEEAGKLLLEQYDDYSMRAKMYTEIHAKP-------------- -----------------AEGESCEYGSLKFFALCGFGGILSCGITHTAVVPLDLVKCRMQ VDPEKYGNIIKGFRVTLKESGIRELGKGWAPTFFGYSMQGLGKFGFYEIFKVLYSGMLGE ENAYLWRTSLYLAASASAEFFADIALCPMEAVKVRIQTQPGWANTLREGLPKLMAEEGMW GFYKGIVPLWGRQIPYTMMKFACFERTVEALYKFVVPKPRADCSKAEQLLVTFVAGYIAG VFCAIVSHPADTIVSKLNQQKGSTFFQIGKNLGFYGMWKGLFPRIIMIGTLTALQWFIYD SVKVYFRMPRPPPPEMPESLKRKLEHWKNERIVAVALLPLIPTALIYVLDMTLSVMVLHA HWRLTGVCQDYIHLSIAAFGSLCYFNYADIG------------NEQVEEDASELIFPKEF ENADTLLISEVQRKQKNESKEEEQELSEVFMKTLHYTSRFSKFKNRETIAAVRGLLIQQK LHKFEFAAIANLCPETADEAKALIPSLEGRFEDEELQQILDDIQTKRSFQY--------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------KESQ AKEQYDQILKFVQGTVAEGAPIVPISAQLKYNIDAVCEYIVKKIPVPERDFTSSPRLIVI RSFDVNKPGCEVDALKGGVAGGSLLRGVLKVGQEIEVRPGIVSKDNEGVLKCQPIKSRIV SLFAEQNDLQYAVPGGLIGVGTKIDPTLCRADRMVGQVIGIVGSLPDIFIELEINYYLLR RLLGVRTEGDRKGAKVQKLTKGEILMVNIGSLSSGGRVLAVKVDLAKIGLTNPVCTEVGE KIALSRKVEKHWRLIGWGQIRRGVTVNP-------------------------------- ------------------------------------------------------------ ---------KGNMTNVLPMIIIGGWINWAFSGFLTTKVPFPLTLRFKPMLQRGVELMSLD ASWVSSASWYFLNVFGLRSMYSLILGQDNAADQTRMMQDQMTGMASGMPQD--------- --------------------MFLWDWFAGILNFLGLYKKSGKLVFLGLDNAGKTTLLHML KDDRMAQHVPTLHPTSEELTMGGMKFTTFDLGGHEQARRVWKDYFPAVDGIVFLIDVFDR ERFSEARSELESLLRDEQIMQAPVLILGNKIDIPGAASEDEIRTVFNLHGQTTGKGTVSR SELRPMELFMCSVLKRQGYGEGFRWLAQYINVLRRNRPGTKTENWSNWPDESFEEMDSTL AVQQYIQQAIRHDFSSIDEILTPPEGQDEGVWKYEHLRQFCLELNDLAVKLQNECNPETC TQMTATEQWIFLCAAHKTPKE--------------------------RVSIKESSVAKLG SVCRRVYRIFSHAYFHHRVLFDEYE--------------------------------MPN IKLQSSDGEVFEVEVEIAKQSVTIKTMLEDEEDEEEPVPLPNVNAAILKKVIQWCSYHKD DPPPPEDDENKEKRTDDISSWDAEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMI KGKTAEEIRKTFNIKNDFTPAEEEQVRKENEWCEEKXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------- --------------------------------------------------YIKYNNLYLV SLSKKNANVAMVFTFLHKIVQVFCEYFKELEEESIRDNFVIIYELLDELMDFGFPQTTDS KILQEYITQEGHKLEVAPRPPMAVTNAVSWRSEGIKYRKNEVFLDVIESVNLLVSANGNV LRSEIVGAVKMRVYLSGMPELRLGLNDKVLFESTGRGKSKSVELEDVKFHQCVRLSRFEN DRTISFIPPDGEFELMSYRLNTHVKPLIWVESVIERHAHSRVEYMIKAKSQFKRRSTANN VEIVIPVPMDADSPKFKTTSGSCKYAPDQNAVIWTIKSFPGGKEYLMRAHFGLPSVTAEE TEGRPPIHVRFEIPYFTVSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRTQMGILEK IAEIENEMARTQKNKATMGHLGLLKARLAKLKRELIEPKGGGGGAGEGFDVAKTGDARIG FVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGCIKYKGAKIQLLDLPGIIEGAKDG KGRGKQVIAVARTSSLIFIVLDVLKPLQHKRLIEYELEGFGIRLNKRPPNITFRKKDKGG INLTATVAQSELDMDTVKTILGEYRIHNADVTLRIDATAEDLIDVIEGNRVYIPCIYVLN KIDQISIEELDIIYKIPHCVPISAHHKWNFDDLLEKMWEYLNLTRIYTKPKGQLPDYNAP VVLKSGSTTVEDFCNKLHRSIIKEFKYALVW----------------------------M AKHHPDLIFCRKQPGVAIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGSYQGRCVIC GGPGVSDAYYCKECTILEKDRDGCPKIVNLGSAKTDLFYERKKYGFKKR----------- --KTGFRKIPVPPNRYTPLKENWMKIFTPVVEHLHLQIRFNLKTRNVELKTCKETKDIGA LQKAADFVKAFTLGFEVEDALALVRLDDLYLESFEVTDVKPLKGDHLARAIGRIAGKXGK TKFTIENVTKTRIVLADSKIHILGSYQNIAIARTAICNLILGSPPSKVYGTMRSVAARSA ERRIKVSKPVVELDGDEMTRIIWAKIKETLIFPYLDVECLYYDLGLPHRDATDDQVTIDA AHAIKKHNVGIKCATITPDEARVEEFKLKKMWLSPNGTIRNILGGTVFREPIICKTIPRL VPGWTQSIVIGRHAFGDQYKATDFVAEGPGKFEIVFTSKDGKETRLPVFEFGEEGGVGMG MYNTCDSIKGFAHSCMQYALKKKWPLYLSTKNTILKRYDGRFKDIFEEIYESQYKKDFEA NGIWYEHRLIDDMVAQGLKSVGGFVWACKNYDGDVQSDVVAQGYGSLGLMTSVLMCPDGK TIEAEAAHGTVTRHYREHQKGNPTSTNPVASIFAWTRGLEHRAMLDDTPELGRWCNLLEK ACVDSIDSGLMTKDLAGCIHGIRNVTPEHYLNTMDFLDAVRDKLNXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------- ------------------LNGPSDKYENVVRWYNHVKSYGSAKDSFPGDGFSLSDIGFGG TDDDDGDDDIDLFGSDAERIKQERLAAYEKRKSQAVVAKSSIVLDVKPWDDETDMKELEK CVRSVRKDGLVWGASKLVPLAYGIKKLQISCVVEDDKIGTDFLEESITAFEDLVQSVDIA AFNKIQVQEVREVTRIERIGAHSHIRGLGLDDALEARNVSQGMVGQTSARRAAGIILEMI KEGKIVGRAVLLAGQPGTGKTAIAMGMAQALGQGTPFTAIAGSEIFSLEMGKTEALTQAF RKSIGVRIKEETEIIEGEVVEIQIDKPAVGSGAKVGKLTLKTTEMETVYDLGQKMIESLT KEKVHAGDIITIDKATGKITKLGRSFTRARDYDAMGSTTKFVQCPEGELQKRKEVVHTVS LHEIDVINSRTQGF------------------------------------------EVHM LDIECFSFLNRALETDMAPVLIMATNRGITRIRGTNYQSPHGIPIDLLDRLLIVSTSPYE EREIKQILKIRCEEEDVEISDDAITVLTRIGMETSLRYAIQLITTAHLVCRRRKGTEVSV EDIKRVYSLFLDESRSTQFLKEYQQEFMFHEMAEFDLTTRMGQYFDRHLVFPLLEFLSVR QIYDEKEMLKGKLDLLSNTAMVDFAMDVYSNLYPDSKIPQSFHEKRAKVVAELKKLQMET EPIIKIFEDEEVMIQTTRDGRQLFEYLTKNHGFKEEYINWLYKFAKFQYDCGNYTGAREY LYLVRALMPNTDRNYMNVQWGKLASEILMQDWDNALEDLNQLQAVIDSSLETLQQRTWLI HWSLFVFFNHPKGRDLIIELFLNQPQYLNAIQTMCPHILRYLTTAVITHKQVVKDLVKVI QQESYTYKDPITEFLLCLYVNFDFDSAQQKLKECEIVLENDFFLTACLKEFIDNARLFIF ETFCRIHQCISIGLLAEKLNMTADEAERWIVNLIRNARLDAKIDSKLGHVVMGTQAISPY QQVMEKTKGLSFRSQMLALTIEKKLGAKQMGVQVETVKPGDGNTFPKPGQMVTVHYVGTL TDGSKFDSSRDRGKPFQFRIGEGQVIKGWDEGVAQMSVGQVAKLTCSPDYAYGAKGYPGV IPPNATLIFEVELLGMEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX------------------------------------------- ------------------------------------------------------------ ----------------------------------------------VELLKAASGTVKLV VRYTPKVLEEMEARFNRQRMTRGRQ---LIALAVAEPTVHFEERFWESRWVNSEHKGSEQ GVFKWSAGKFYGDPEKDKGIQTSQDAHFYGISAKFDKPFSNEGKTLVIQFTVKHEQNIDC GGGYVKLFPSDVNQKDLHGETPYLIMFGPDICGPGTKKVHVIFNYKGKNLLTKKDIRCKD DVFTHLYTLIVRPDNTYEVKIDNKRVEGGDLESDWDFLPPKKIKDPEAKKPEDWDERETI DDPEDKKPEDWDQPEHIPDPDAKKPDDWDDEMDGEWEPPMVDNPEYKGEWKPKQIPNPAY KGKWIHPEIDNPEYSPDENLYRYTDIGAIGFDLWQVKSGSIFDNIIITDDESHAEKIGDE TWGVTKDPEKKMRDEQEEEDKKKREAEAASKKDDEDEDDEPDEDMDSTLPEPTLYIVKAI LILDNDGNRILSKYYDDQFPTVKEQKNLFNKTHRANAEIIMFEGLTCVYKSNVDLFFYVI GSSNENELILVSVLHCLYDAISMMLNKNVEKRVLLDNMSGALLAVDEICDNGIILESDPT AVANRISTRSDDIPLGEQTVASVLQSAKEQIKWSLLKMNIFRLSGDLCHLLAIIILLLKI WKTRSCAGLSGKSQIMFAMVYTSRYLDLFTSFISLYNSVMKVIFILTSFATVYLIYMKFK ATYDSNH----------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------IGLKTAKGTKQLK LDPSIYESIQKEKVEVGDVIYIEANTGAVKRQGRSDTFATEFDLEAEEYVPLPKGDVHKK KEVIQDVTLHDLDVANARPQGGQDIISMMGQLMKPKKTEITDKLRKEINKVVNKYIDQGI AELVPGVLFIDEVHMLDIECFTYLHRALESTIAPIVIFATNRGKCTIKGTEDIVSPHGMP LDLLDRVMIIRTLPYSQEEMQQIIKIRATTESIQISDDSLQMLGEIGVKSTLRYAVQLLT PSNLLAKINGVDSIGRAEIEEINELFFDAKSSAKILAEQEDKYMKDFEMDDEGDQSVKKL KQKVKVRKGRGF-TNTGIEEYEAMETTGPGPQRSVEGWILFITNVHEEATEDDIHDLFAE YGDIKNLHLNLDRRTGFLKGYALVEYEMFSEAQSAMEALNGTEVLGQKINVDW------- ---MSYQLYRNTTLGHTLQESLDELIQVSQITPQLALKVLLQFDKAINNALATRVKNKVT FKGHLNTYRFCDNVWTFVLNDVEFRTVGKVKIVACEG--TFLFTSESVGEGHPDKLCDQI SDAVLDAHLKQDPSAKVACECASKTGMIMLLGEISSKAHVDYQKVVRDTIKHIGYDDSSK GFDYKTCNVLSALEEQSPDIAQGVHEGRDEADIGAGDQGLMFGYATDETEEAMPLTVILA HKLNAKIAELRRNGALPWARPDSKTQVTCEYRMQKGACVPQRVHTVVISLQHSEDITVEH LRKELMEKVVKVVIPSKYLDDNTVYHIQPSGRFVIGGPQSDAGLTGRKIIVDTYGGWGAH GGGAFSGKDFSKVDRSAAYAARWVAKSLVKGGLCRRVLVQLSYAIGVAEPLSIFVSSYGT GVRPDSELLRIVKENFDLRPGMIVKELDLKRPIYQKTATYGHFGRSEFTWEQPKIL--MA GSALRRLMAEYKQLTLNPPEGIVAGPLSEENFFEWEALITGPEGTCFEGGVFPARLTFPV DYPLSPPKMKFTCDLFHPNIYPDGRVCISILHAPGDDPMGYESSAERWSPVQSVEKILLS VVSMLAEPNDESAANVDAAKTWRDDRAKFNEIAHRTVRKSLGLMRLERCYFCSSTIYPGH GIQFVRNDCKLFRFCRSKCHAAFKKKRNPRKVKWTKAFRKAAGKELTVDPSFEFEKRRNV PVKYDRQLWRNTVEAMKKIDEIRTKRQNLLLLNRLRKKEGIRKE---------------- ---MTTYKVVMVRHGESEWNKQNKFCGWFDADLSELGIEEAKSAGKMLKEKGYSFDIAFT SVLKRAIKTLYFVQDELDLHWIPVVRHWRLNERMYGALQGLNKAETAAKHGEEQVKIWRR SYDVPPPPVDVSSEHWPGHDPKYQYVDRNLIPKSECLKDTVARVLPFWYDAIVPEIKKGQ RVLIAAHGNSLRAMVKYLDNMSDADIMALNIPTGIPLVYELDGDLQPIKHYYLASEEQVK AAIDKVAAQGKAKMELHDIFYNKPEYIETASGNKVSRQSVLCGSQNIVLNGKTIIMSDSI VRGDLANVRIGRHCIVSRRAVIRPPFKKFSKGVAFFPIHIGDHVLIEEDSIINAAQVGSY VHIGKNCIIGRRCILKDCCAIADNTVLPPETVVPPFTLFSGSPGMSFFFGSRGXQTFKPK KNIPEGTHQYDLMKHAAATLGSGNLRQAVTLPEGEDLNEWVAVNTVDFFNQINMLYGTIT EFCTEDTCPVMSAGPKYEYHWADG------------------------------------ ------------------------------------------------------------ -------------------MGIDICHKHKRKVVRREPKSQDIYLRLLVKLYRFLARRTGC RFNKIILKRLFMSKTNRAPLSVASLARHMKKPGRENKIAVCVGTVTDDIRIYKLPKLKVC ALRVTRPARAHILKAGGEIMTFDQLALKAPRGQNTVLLQGPRKAREANRHF--APGVPHS HTKPYVRSKGRKFERARGRRASRDYK-DLKHGNIHGSYQLASTVEVLLHVISKTEPSSVK ELISFIREQGQRLMSAQPSETVVGNMVCRVLKIIRDECVTEAIKELLVELDTSQQALEHI HSKEVIRTVKAFFKKSFKVIVVEYQGQKMAASLVSAGISTTVITDSAVFAMMARVNKVII GTHTVMANGGLKAIGYHAIALAAKYHSVPLVVCAPMYKLSPQYLCSYDVAFNKFVSPED- -------------------------------------MIIPVRCFTCGKVIGNKWETYLG LLQAEYTEGDALDALGLKRYCCRRMLLSHVDLIEKLLNYAPLEKKSPEAVEGRKHIDVQT ELYLEELSDRVEEADVECQTDAFLDRPPSPLFIPAKSGRDIATQILEGDLFDFDVEVKPI LEVLVGKTVEQSLLEVMEEEELYNLRAQQRAFEELRNSELVEQQRLEEQERRHREEKERR MKQQREILRKEKETADKIAARAFAQSYLADLVPSVFGTLSDNGYFYDPVERDVEQGFLPW LMDRVEDQLNRSVLGRTVLDGLIRDVVQQRLEQY--MKARGDLKEYKVIGRMRPTDKTKK PPLYQMRIFAPDRPTAVSRFWYFSSQLKKMKKTHGEILLCQQIFEKRPTKIKNIGIWLRY DSRSGTHNMYKEYRDLSVAGAVTQCYRDMGARHRARTGSIQIIRCEVIPASKCRRPYIKQ --------------------------------SAHQEMKNFWKKNQGRPSSPWVIYRPHL PMLTSLTHRMTGIAMGVALYGISIGLFLAPGDFPSHIEFVKSLHLSPLILFPAKTVMAFP LVYHYLNGIRHLAWDAGYGFKLATQYKTGWSILASSSYWSGSIALSAYRDQHFKGSRQEQ EQLLLRSTTLYVGNLSFFTTEEQIHELFTRAGDVKRIIMGLDKFKKTPCGFCFVEYYTRE DAENAMRYANGTRLDDRVVRTDWDVGFKEGRQYGRGKSGGQVRDEYRTDYDSGRGGYGKI IQQKV------------------------------------------------------- ------------------------------------------------------------ --------TSKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGQKNEKYCVFANFSVTGG KWIVSGSEDNMVYIWNLQTKEIVQKLQGHTDVVLCCACHPTENIIASAALENDKTIKLWR SDV--------------------------------------SGINIVLSXKKSYQSHLKD YMKSLAALQFYCGLAIVEWDTPYMYFFKDGIIPEKVMAVEYKDGIVVAADSRTTTGAYVA NRVTDKLTKITDRIYCCRSGSAADTQAIADVVSYNLGFHKMQMDEEPLVKTAATVFQEMC YSYRDSLSAGIICAGWDHKLGGQVYSIPLGGMCVRQPLTIGGSGSTYIYGYVDSAFKEQM TKEECLQFCTNAVALAMSRDGSSGGIIRLATVNKDGVERKTILHDDLPKFXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXL-------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------FMTKGSEQESMARLKKLMTIMDS----------- ----------------------NDQELDSYE--GAKLFTRGRTQRVARGAGVSVREVQEL ITQKFAQMVKKMGGIKGLFK-GGDMAKNVPAQMAELNKQMAKMMDPRVLQQMGGMPVLQG MMRKFQSSAMSIMSYNGAAIVAMKGKDCVAIASDCRFGIQAQTVATNFQKIFEMGPHLYL GLPGLATDVQTVGQRLKFRLNLYELRENRRIKPKTFLSMVSNLLYERRFGPYFVEPVIAG IDSKTSEPFIAALDLIGCPMITEDFVVSGTCTEQLYGMCESLWVPDLEAEELFQTISQAL LNAVDRDAVSGWGAIVYIIEKDKVTTRTLKARMDMTSKDYYFDSYAHFGIHEEMLKDEVR TLTYRNAMYHNRHLFKDKIVLDVGCGTGILSMFAAKAGAKKVIGIECSSIVEYAEKIVKA NKLDNVVTLVRGKVEEVSLPDGIEKVDIIISEWMGYCLFYESMLLTVLYARDKWLAPGGL IFPDRATLYVCAIEDRQYKDEKINWWDNVYGFDMSCIRKVAIQEPLVDVVNPKQVVTNSC LVKEVDIYTITPADLTFEAPFHLQCRRNDYIQALVTYFNIEFTKCHKRTGFSTGPDAEYT HWKQTDEYLTVKTGEEIYGTLSVRPNKRNNRDLDFKLDIDFRGELSEMVETLTYKMRMVK EDKATWKSNYFLKLVQLFDEYPKCFIVGVDNVGSKQMQHIRIALRVMMGKNTMMRKAIRG HIETNPALEKLLPHIKGNVGFVFTKADLSEIRKVISENRVAAPARAGAIAPLDVTLPAQN TGLGPEKTSFFQALAIPTKISRGTIEIQNDVKLIRQGEKVGASEATLLNMLKISPFTYGL VIKQVYDSGTIFDPAILDVTDDDLRSRFMEGVANVASLSLAIGYPTVASAPHSIVNGFKN LLAVAAVTDITFKEAETMKE------LIAVIGDEDTCTGFLLGGIGELDKHRQPNFLVIN KDTSISEIEEAFRKFTTRSDIAIILINQNVAEMIRHEIDAYSQTIPAILEIPSKEAPYDP AKDSILRRARGML------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXMPHVKTWDDFARHAEMLYLNDPIKTRFVVKYRHCDGKLTVKITDDQSCYMYQ TEHAQDVKKLEKLTSLLMRHMASKDLYEEVKLYRNNREREHYDNMADLYAVINTLQCLEK AYIKDVVTPKEYTAACSKLLVQYKAAFKQVQGTEFPTVEAFMKKCKLDCPAALERIKEGR PITIKDDKGNTSKCIADIVSLFITIMDKLRLEIRAMDEIHPEMRDLMDTMNRLSILPADY EGKVKVQEWLETLSSMQAADELSDTQVRQLLFDLESAYSEFNRILHNMLSSMLKSHQSRQ YIRKELQEKRKRDAIAATALSHALVDHLNAGVAQAYVNQKKLDTETKLLQVNAAQFAKQT TQWLKLVEDFNQALKEXGDVENWSKSIETDM------------VRMIVKPISGDKNGQTR KVRINRMPRSYPTEDRRKKRRKCFKDHKHKLRTSITPGTVLILLAGRHKGKRVIFLKQLK SGLLLVTGPYAVNGCPLRRINQIYVIATKTKLDISGINLPERLTDQYFRRMKLKKPKQNE GEIFDTKKEEYTVSEERKKDQVVVDNQIMDVIRKNPEKKLLLAYLGAMF----------- --LEWLFGRKKTPQELLRQNQRALNKAMRDLDRERQKMEQQENKIKMDIKKMAKQGQMDA VKIMAKDIVRTRRYIKKFILMRANIQAVSLKIQTLKSNDAMAQAMKGVTKAMATMNKQLK LPQIQKIMMEFEKQSEIMDMKEEMMNDAIDDAMGDEDDEEESDALVSQILDELGLQMADQ LSELPGTGQSTTKQPVGVSDADADLEARLENLRRQ-------------NKKTGQKEDLVS CADCGRSGHPSCLQFTPNMIISVKKYPWQCIECKSCGLCGTSDNDDQLLFCDDCDRGYHM YCLKPPLSEPPEGSWSCHLCIEEFYGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------IEPQYIKDEVL PPFFKHFWKQSMALDRRNYRQLVDTTXKLLTKLARAEIISRVVDDLKDESEXYRKMVMET IEKIMANLGSADIDSRLEEQLIDGILYAFQEQTTEDVVMLNGFGTVVNALGKRVKPYLPQ ICGTILWRLNNKSAKVRQQAADLISRIAVVMKTCQEEXLMGHLGVVLYEYLGEEYPEVLG SILGALKSIVNVIGMTKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGAEFVS AREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVC TTVAIAIVAETCSPFTVLPALMNEYRVPELNVQNGVLKSLSFMFEYIGEMSKDYVYAVSP LLEDALMDRDLVHRQTAMSAIGHLALGVYGFGCEDALNHILNYVWPNIFESSPHVVQAFM AAIEGIMVGLGPTKILQYCMQGLFHAARKVRDVYWKVYNTVYIGAQDALVPAYPRIPDDE KNTYIRYELDYIL----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------EYEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGIN PFDSQEAKPYKNDPEILAMTNLVSAYQNNDINEFEKILKTNRRNIMEDPFIREHIEDLLR NIRTQVLIKLIKPYTRIHIPFISKELNIDANEVENLLVSCILDDTIHGRIDQVNQLFELD VGGAKYNAMEKWTQQLSTLHQAIINKMAVLLMGKSGSGKTSMRSIIFANYIARDTRRLGA TIDVEHSHVRFLGNLVLNLWDCGGQEAFMESYFASQRDNIFRDVEVLIYVFDVESRELEN DMHYYQSCLEAILQNSPDAKIFCLIHKMDLVPDDQRDIIFHQREDDLKRLSKPLATSIWD ETLYRAWSSIVYQLIPNVDKIEMNLNSFAKVIDADEVLLFERATFLVISHCNTKPHPDVH RFEKISNIIKQFKLSCSKLAASFHSMEVRNSQFAAFIDMFTANTYVMIITSDSSIPSAAM LINIKNARKHFERLEKLE-MLSFSTRLFSVLRFESVIHEFDPYFNYRTTRFLTEEGFYNF HNWFDDRAWYPLGRIIGGTIYPGLMVTSAVLYHVMHFVNLTIDIRNVCVFLAPLFSSLTT LVTYLLTKELMDAGAGLVAAAMISIVPGYISRSVAGSYDNEGIAIFCMLLTYAMWIKSVK TGSVFWSVMCALSYFYMVSSWGGYVFLINLIPLHVLVLMLTGRFSHRVYVAYSTMYCLGT VLSMQISFVGFQPVQSSEHMAALGVFGLCQIHVFVDYVRSKLTHDQFTVLFRRAV----- ---------------FYSLLDPSYAKNNIPIIASVSEHQPTTWSSFYFDLQLLVFLFPAG LYFCFKKLTDANIFIIMYGVTSLF----------------------AVSATLTTFMKNLD VAKRRDTNYPIKNEVATGVVIMMTLFLLTYTFHCTWVTSEAYSSPSIVLAARASDGGRII FDDFREAYYWLRHNTPEDSKVMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMAS TEDKAYEIMRELDVNYVLVIFGGLAGYSSDDINKFLWMVRIGGSTDRGQHIKEQDYYTPQ GEFRIDKEGSPILLNCLMYKMCYYRFGSVYTEAGKPTGYDRVRNTEIGNKDFELDVLEEA YTTEHWLVRIYKVKDLENRG---------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------ETPNKKNKLTM MLTS-EXGIADDIEAEVVQITWPRKRLGEFFQNKYDWDLLAARSIWAFGPDATGPNILVD DTLPSEVDKGLLSSVKDSIVQGFQWGTREGPLCDEPIRNTKFKILDAVIAQEPIHRGGGQ VIPTARRVAYSAFLMATPRLMEPYFFVEVQAPADCVSAVYTVLARRRGHVTADAPIPGSP MYIIKAFMPAIDSFGFETDLRIHTQGQAFCLSVFHHWQIVPGDPLDKSIVIRPLEPQPAT HLAREFMIKTRRRKGLS----------------------------QETFSLFDYRGDGKI FAHQVGEVLRAMGQNPTEAEVKKCSDPDYRLSFEQFLPILQTVMRNRDTSTLEDFVEGFR VFDKEQNGTMSSAELRHLLTSLGERLTDEEVSELIAGQEDAHGNINYEEFVKMVMSGMPE LTFNIDAGYLEGLCRGFXVEFLRQADYLNIVQCETLEDLKLHLQSTDYGHFLANEASPLT VSVIDEKLKEKLVIEFQHIRNQSVEPLSTFLDYITYSYMIDNIVLLITGTLHQRSISELI PKCHPLGSFEQMEPXNIASTPAELYNAVLVDTPLAPYFIDCISEQDLDEMNIEIIRNTLY KAYLEDFYDFCKKLGGATQ----------------------------------------- ---------------------------------------GDKTLEDKFFEYEVMLMKKAF MQQFHFGVFYAFIKLKEQECRNVIWIAECVSQRHRDK----------------------- -------------XLVDWSSQNVLSVGLGSCVYLWSACTSQVTRLCDLQCDDDSVTSVSW SERESXVSVGTHKGYVQIWDVTANKKIHTLEGHSARVGALAWNSDILSSGSRDRFILQRD IRTPSLLPQRRLGGHRQEVCGLKWSPDHQHLASGGNDNKLFVWNMSSTSPVQAYTEHLAA VKAIAWSPHQHGLLASGGGTADQCIRFWNTLTGQPLQCLNTGSQVCNLAWSKHSNELVST HGYSQNQILVWKYPSLMQIAKLTGHSFRVLYLAMSPDGESIVTGAGDETLRFWNIFSKTR SNKDSKSVLNMFTRIR-------------------------------------------- ------------------------------------------------------NYHAGF AMFGAGLTVGFSNLFCGLCVGIVGSGAALADAQNPTLFVKILIVEIFASAIGLFGIIVAI LQTNNAKMGNVMAATRRLQKELSDNVEETNILKWNGTLFPKDPPYNKGAFKISIEFPSEY PFKPPKITFKTKXYHPNIDEKGQVCLPIINAENWKPATKTEQVLQALAALIDRPEPEHPL RADLAEEYTKDKKKFMKAAEDYTKKYAEKRPAD--------------------------- -----------HGHAKVHLVGLDIFTGKKYEDICPSTHSMNVPIVTRTEYQVVDVSNGYV SIMDDNGELREDLKLSATVIKAMNKEQISDVKS------GSEGVCVDHNGHIVVVDNKAS CVFVFQSNGKLLHKFGSRXEHQFAGPHFCAVNRDNDVIVTDFHNHCVKVYTEGTFRFSFG SNGEGNGQFNAPTGVAVDDNGHILVADWGNSRIQV---------------PRGIAVTSDG YVLVADRDNHCVKKFRYL------------------------------------------ --------------------------------NMIKLYGKPIRVNKASAHQKAQDVGANI FIGNLDPEVDEKLLYDTFSAFGVILQTPKIMRDPETGNSKGYAFISFASFDTSDAAIEAM NGQYLCNRAITISYAFKKDSKGERHGSAAERLIAQQNPLSQTDRPHQLFADAPPPPAQMP MAPPPPPPVSGMVSSVP-----SNTYPTSMPP---------------------------- ------------------------------------------------------------ -------------LKVPPPINQFTQTLDRQTATQLFRLLDRYRPESRHEKKIRLRLRAED RAAGKPDVPTKRPPVVRSGVNTVTTLVEQKKAQLVIIAHDVDPIELVLFLPALCRKMNVP YCIVLGRVVRRKTATCLALTQVNPEDKSSLNKLVEAVKTNFNERYDEIRRHWGGGIMGAK SQARIAKLEKIKARELAQKMRYVAAYLLAVLGGNTSPKAKDIKQILSSVAVDVDDDSLSR VIKQLEGKDLKELIAEGHSKLASVPAAGAVAVAEEKKEE------------MPISRIHAR QIFDSRGNPTVEVDLTTERGTFRAAVPSGASTGIYEALELRDKDPKAYHGKGVSQAVNNV NTRIAPALVLDLTNQAAIDKIMLDLDGTPNKGTLGANAILGVSLAVCKAGAAKKGVPLYR HIADIAGNSEVILPVPSLNVINGGSHAGNRLAMQEFMILPTGASSFTEAMKMGTETYHHL KNVIKKRYGQDACNVGDEGGFAPNIQSNEEGLELLTLAIENAGYTGKIQIAMDVAASEFC KKYDLDFKNKDSNPDNWLTSDQLLEVYKGFIAKYPVVSIEDAFDQDDWDAWTKMNHIQLV GDDFLVTNPNRVREAIEKNSCNALLLKVNQIGTVTEAIEACKMSQNAGWGVMVSHRSGET EDTFIADLVVGLCTGEIKTGAPCRSERLAKYNQILRIEEELGSKAKYAGVHFRNP----- -----------TLFRRFYDRSDIPVALDSNCRGPKLRWLVEIEKLDYHHFLPLFFDGMRD TKEPYATIATLGAKDMIIHAPNKILNVVPQLIIPIKKALETKDPDVIVRMTQCIQELVRS DKLVGEALVPYYRQILPVFNIFINRHKNXGDGILYGQNKNVDLGSLIDETVHMLERYGGE DSYINIKYMIPTYESCIMNAPPTFETFLLYDGEKKVIIERDTKVPNAAIFTVNKEDHTLG NAIRTQLLKDPQVLFAGYKVPHPLESKFVLRIQTTPDYSPQEAFTNAITDLISEVSLLEE RFKDAIREKQEGDEDHRRKWDKDEYEKLAKARLGLDDSGREPPVKRELLKPRDYKVDLDS KLGKSQVITKTTPASQQGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRIERSSLE QVKRRFELNKKKQEEKKKEYDFEERMKELKEEEERQKAYKREKRKERKRKATGSSGDPDV ASLMGFSGFGPSKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--- -----------------------------------------------KGEADRTLIYITL YITECLKKLQKCTXKNQALKEMHTLAISRFYLPGEAQFPLNGMFTRPANRQEEDVMRAFF TQLRQETGVRLTDKVFDPVTDKPSKWWTCFAK-------------SGPYNYSYIFKYIII GDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVT RSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIFXIGNKCDLEAQRDVTYE EAKQFADENGLMFLECSAKTGENVEEAFLDTARKIYQNIQDGSLDLNAAESGVQHKPSAP RNPLSTDQTQNKEGCSCMAIHAVCVLKDGPVTGTVHLTEEG-VTLTGEITGLEPGKHGFH VHEFGDNTNGCTSAGGHFNPYGKVHGGPDDETRHVGDLGNVIAGHXRIXDSLVKLTGPDS VIGRTLVVHVGEDDLGRGGDEEA------------------------------------- -----------------------------------------------------STAISLF YQLPEKDLETAFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQA IAERIKPVLFMNKMDLALLTLQLGAEDLYQTFSRIIESINVIIATYADDEGPMGNIHVDP SRGTVGFGSGLHGWAFTLKQFAEMYADKFKIEEPKLMRRLWGDQFYNFCRGFTQYILDPI YKVFEFCMPKDETLKLVDKLGIKLTSEDKDLIDKQLLKVIMRKWLPAGDALLQMITIHLP SPVTAQRYRMEMLYEGPHDDEAALGIKNCDPNGPLMMYISKMVPTSDKGRFYAFGRVFSG VVSTGMKARIMGPNFIPVKAIQRTILMMGRYIEPIEDVPCGNVCGLVGVDQYILKTGTIS TYEHAHNLKVMKFSVSPVVRVAVECKNPADLPKLVEGLKRLSKSDPLVQCSIEESGEHIV AGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETVNSKSDRTCLSKSPNKHNRLFMVA APLPDGLSEEIDKGEISARQEQKERARYLADNFEFDVTEARKIWCFGPDGTGPNMVVDCT KGVQYLNDIKDSVVAGFQWASKEGVLCEENMRGVRFNILDVTLHADAIHRGGGQIIPTTR RCLYACVLTAEPRLMEPVYLVEIQCPEQAVGGIYGVLNRRRGVVIEENQVVGTPMFMVKA YLPVNESFGFTADLRSNTGGQAFPQCVFDHWQVLIVTETRKRKGLKEGVPPLDNFLDKLM LPLSLLRTAVNHPMLVELKNGETYNGHLVSCDNWMNINLREVICTSRDGDRFWRMPECYI RGSTIKYLRIPDEVIDMVKEDMIQKSKGRGDSKGRGRGGPGRGAFGRGAP--VRGGRG-- ---NEYKLSSPPDDGISSVKFAPQSSQFLLVSSWDCGVRLYDVTANHMRIKYQHSKPVLD CCFQDPVHAFSGGLDATLKMYDFNTNTEAVLGKHDGAIRTVEFSSEVNVVVTGSWDSTVK LWDPRSRCLAGSFSQPDKVYTMGLCGDKVVVGTAGRRVLVWDLRNMGYVQQRRESSLKYQ TRCIRCFPNRQGYVLSSIEGRVAVEYLDPSPEIQKKKYAFKCHRIKEDGVEKIYPVNAIS FHSQHNTFATGGSDGFVNIWDGFNKKRLCQFHRY-------------------------- --------------------MDFQHRAGGKTGTGGVASASESNRDRRERLRQLALETIDL NKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQANLARRAAKEAKEAPAQPAPE KIRVDIKKFVKIGRPGYKVTKQRDPETGQQSLLFQIDYPEIVDGVIPRHRFMAAYEQKVE PPDKKWQYLLFAAEPYETIGFKVPSREVDKDASRFWTHWNKETKQFFLQFAFK------- ------------MDDELEIYRLWRIRKTVMQLCHDRGYLVTQEELDQTLDQFTQQYGDKP SERRPARSELTVLVAHNDDPTDQMFVFFPEEPKVGIKTIKTYCHRMQEENISRAILVVQQ GMTPSAKQSLVDMAPKYILEHFLEAELLVNITEHALVPEHVVMTPEEK------------ ------------------------------------------DGKKEVGTVIGIDLGTTY SCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGDRLIGDAAKNQLTTNPENTIFDVKRLI GRRWEESTVQHDVKFFPFKVINKNNKPHIEVAVGAKGKVFAPEEISAMVLLKMKETAEAY LGKTITNAVVTVPAYFNDAQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKEGEKNI LVFDLGGGTFDVTLLTIDNGVFEVLSTNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRK SNRAVQKLRREVEKAKRTLSSQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMK PVQKVLDDADLKKTDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAV QAGVLSGEEDTGDLVLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQIFSTAADNQPV VTIQVFEGERPMTKDNHLLGKFDLTGIPPAPRGVPQIEVTFEIDVNGILKVTAEDKGTSN KNSITINNDQNRLSPEDIERMINDAEKFAEDDKKLKERVESRNELESYAYSLKNQIGDKE KLGAKLSEDDKETIEKAINEQITWLEANQDADTEDFKAHKKELEEVVQPIISKLYQDAPP TG-DEERDEL--------------------------KEMQSEVEKQMSPEDKVDCDSRSI WVGNVDYGATAEELEAHFHGCGSVSRVTILCDKFTGHPKGFAYIEFADKDSVDTAMALDG SFFRGRQIKVTAKRTNRPGISSTNRPPRGRIRRARTS-YYGGYAPRAR-VSRFRSRRTAY YSPY-------------------------------------------------------- ------------------------------------------------------------ ---RVKDQIDEEARVNAEIESFLRTHTERLQKMVEHWMEKYDKDVEAKQKELDILKASKA KDLDRLQELTKLYAEYEQVVVEDRIEKEKARRKAEQEAEELKASIKIQSWWRGVMVRQGL GPYNKKKKKKPKIGINGFGRIGRLVLRAALAKVEVVAVNDPFIDLDYMVYMFKYDTMHGR YKGTVTLIVDGKAIAVFNKMKPSEISWGSVGADYVVESTGVFTTTEKAKAHLEGGAKKVI ISAPSADAPMFVMGVNQEKYDPSMTIISNASCTTNCLAPLAKVIHDKFGIIEGLMTTVHA YTATQKTVDGPSAKAWRDGRHAAQNIIPASTGAAKAVGKVIPDLNGKLTGMAFRVPVPDV SVVDLTCRLAKEASYDEIKAAVKGPMKGILGYTEDFVVSSDFIGDTHSSIFDARAGIALS PTFVKLVTWYDNEFGYSCRVVDLITY---------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------TMWFGESEANVREIFDKARSAAPCVLFFD ELDSIAKARGGNVGDGGGAADRVINQLLTEMDGMSSKKNVFIIGATNRPDIIDPAILRPG RLDQLIYIPLPDEKSRISILKANLRKSPVAKDVDVTFIAKMTHGFSGADLTEICQRACKL AIRQAIEADIRREKERLENPDDYDPVPEINRAHFEEAMKYARRSVTDNDIRKYEMFAQTL QQSRGFGG---------------------------------------------------- ---------------------------------------------------------SES IQVAQHDAPVKTVHWIKAPNYTCLMTGSWDKTLKFWDTRSPNPMLTIQLPERCYCADVLY PKAVVGTAGRGIIIYNLENQPTEFKRFESPLKYQHRCVSVFIDKRTNQPTGFALGSIEGR VAIHYANPQNPKDNFTFKCHRGNVQDIYAVNDIAFHPVHGTLATVGSDGRFSFWDKDART KLKTSEQLDQPISCCAFNAQGQIFAYASSYDWSKGHEGFDPQKMKPHIFLRSCFDELKPS QKK--------------------------------------------------------- ------------------------------------------------------------ ---------------------------LSRYATEDALREQESSMSDFSEDEAQDMELXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- -------------------------------DENLIYWPRYIKQKCKQRFTRITQYLIRI RKLKLRRQKKLVPLSTKIERRERRREQKALIAAQLENAIEKELLERLKKGTYGDIYNFPQ MAFDEALKEVEVSDYNTDD--------------------FIQGRFQAQPRIKKFKIYRYD PDQPGSKPYMKEYEVDLNKCGAMVLDALIKIKNEIDATLTFRRSCREGICGSCAMNINGA NTLACLCPIDTDTGKTSKIYPLPHMYVVKDLVPDMNNFYAQYKSIEPYLKKKDMGEDDIG KVSLKQSPKDREKLDGMYECILCACCSTSCPSYWWNGDKYLGPAVLMQAYRWVMDSRDDF KQERLEQLRDEWSLFRCHTIQNCTKTCPKGLNPSAAIAEMKRLLAGYESTGIPRQDIRPN HTIYINNLNEKIKKDELKKSLYAIFSQFGQILDIVALKTLKMRGQAFVIFKDINSATNAL RSMQGFPFYDKPMRISYSKKDSDVIAKMKGTFVERPKKKKRDSQNKKKKNKVSTAIPEQP PHHILFLTNLPEETTEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENEGQAGAAKDALQ GFKITPSHAMKISFAKKMDSKGRRVVICDNGTGFVKCGFAGSNFPAHIFPSLVGRPILRS TVKIGDIELKDLMVGDEASQLRAMLEVNYPMENGVVRNWDDMIHLYDFTFGPEKLNINPR ETKLLLTEPPMNPIKNRERMVQTMFEHYQFDGLYIAIQAVLTLYAQGLMTGVVVDSGDGV THICPVYEAYSMPHLTKRLDIAGRDITKYLIKLLLLRGYAFNHSADFETVRLMKEKLCYV AYDVAQEQKLAVETTVLVETYTLPDGRVIKVGGERFEAPEALFQPHLINVEGAGIAELLF NTIQSADMDTRPEFYKHIVLSGGSTMYPGLPSRLEREIKQLYLERVLKGDAERLSKFKIR IEDPPRRKHMVFIGGAVLAEIMKDKDSFWMSRAEYEEQGLRVLQKLGVQMSDTVGKTISC KAAVAWEAKKPLSIETIQVAPPKAGEVRIKLLATGVCHTDAYTLDGFDPEGLFPVVLGHE GGGIVESVGEGVTSVKPGDHVIPLYIPQCGECKFCKSPKTNLCSKIRATQGAGKMPDGTS RFSCNGKELYHFMGCSTFSEYTVVAEISVCKINPEAPLDKVCLLGCGISTGYGAALNAAK VEAGSNVAVWGLGAVGLATIMGCKKAGAARIIGIDINPDKFKTAKEFGATECINPKDHQE PIQTVLVNMTDGGLDYTFECIGNVATMRAALESCHKGWGVSIIIGVAAAGQEISTRPFQL VTGRVWKGTAFGGWKSRESVPKLVEEYLKKELKVDEFVTHTMNLDKINEAFDLMHGGKS- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------VPIYEGFAMPHSIV RADIAGRDVTRYLQLLLRKEGYDFHTTAEFEIIKTIKERACYLSINPQKDETIDTEKASY TLPDGNVVEVGPARYRAPELLFRPDLIGEECLGIHEILTSSILKSDIDLRRTLFSNIVLS GGSTXFKGFGDRLLSEVKKLAPKDIKIRISAPQERLYSTWIGGSILASLDTFKKMWIS-- ---------------DPHKISKVVVHPLVLLSVVDHFNRMGKIGNMKRVVGILLGSNRQG VLDVSNSFAVPFDEDEKEKDVWYLDHEYLENMYAMFKKVNARERIVGWYHTGPKLHQNDI AINELIKRYCQNSVLVIIDAKPKDLGLPTEAYISVEEVHDDGTPTTKTFDHVPSEIGAEE AEEVGVEHLLRDIKDTTVGTLSQRISSQLSGLKGLQCQLQDIHSYLEKVSSGKLPINHQI IYQLQDVFNLLPDINLQEFVRSVYIXNNDQMLVVYLAAMIRSIIALHNLINNK------- --------MGLLISKLWSLFSNEEHKVIIVGLDNAGKTTIXYQFLMNEVVHTSPTIGSNV EEVIWKNIHFIMWDIGGQDSLRTAWN---------------------------------- ------------------------------------------------------------ ------KEIPIRRVLLNDPSQLPSDYSQTPGGTLFSTTPGGTRIIYDRNFLMQCRNSPLA KSPPPNLPKIPGVTTP-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---EVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLAWNKQ DPNYLATMAMDAFEVIILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHVCTAADDHQAL IWDIQQMPRAIEDPILAYTAGGEINQIQWSSTQPDWISICYNN----------------- ------------------------------------------------------------ --------------------------------------------------------NSTV PIASEVFKKRGVYDPSKIFGVSTLDVVRANTFIAEARDLDVNQVNCPVVGGHSGVTIVPL MSQCTPPVSFPQEDRDKLTKRIQNAGTEVVEAKAGAGSATLSMAYAGARFTDSVLQALAG EEGIVECAYVRSDETEAKYFSTPLLLGKNGLDKNLGLGKILDYELNLIKAALPELKKNIQ KGEDFVLK---------------------------------------------------- -------------------------------------PEGACVGLVKNLALMSYISVGSQ PSPILEFLEEWSMENLEEIAPSAIADATKIFVNGCWVGVHRDPEQLISTLKKLRRQMDII VSEVSMIRDIRDREIRIYTDAGRICRPLLIVXNQKLLLKKRHIDLLKEREYNNYSWQDLV ASDVVEYIDTMEEETVMIAMTPEDLGEKDISYCSTYTHCEIHPSMILGVCASIIPFPDHN QSPRNTYQSAMGKQAMGVYITNYHVRMDTLANVLFYPQKPLVTTRSMEYLRFRELPAGIN SIVAIATYTGYNQEDSVILNESAVDRGFFRSVFYRTYKDAESKKGLDQEELFEKPDRKYV TGMRHAVYDKLD------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------VQKISKLLHE YGYHLRGNEILYNGHTGRKLNAQIFLGPTYYQRLKHMVDDKIHSRARGPVQILNRQPMEG RSRDGGLRFGEMERDCQIAHGAAQFLRERLFEVSDPYRVHVCNLCGLIAIANLRNNTFEC RGCKNRTHISQIRLPYACKLLFQELMSMSIAPRMMVLCVQPSGGFSFENCKRNAVLQKAL KPPTTRKTGTTICGVIFKDGVVLGADTRATEDTIVADKNCSKIHYLSNNIYCCGAGTAAD TEMTTQLISSQIELHRLNTGRLPRVSTANRLLKQMLFRYQGYISAALVLGGVDVTGPHLY SVYPHGSTDALPYVTMGSGSLAAMSVFEDRYKLDMEREEAMKLVCDAIRAGIFNDLGSGS NVDLCVITKKVDYLRPFEEANQKGKRQGNYTYKPGTTAILSEEVKKIEFDVIMSKVTFKI TLTSDPKLPYKVLSVPENTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPSQSAGNVFL KHGSELRLIPRDRVG-MAFTFVAFCYILALILSAFLIFFVIYHIIAFDELKTDYKNPIDQ CNSLNPLVLPEYLLHLLYNILFLFAGEWFTLLLNVPLIAYHIKRYMNRPVMSVPGLYDPT SIMNADELNRAQKEGWIKLAFYLLSFFYYLYSMIYELVSSMGLLTILKKMKQKEKEVRLL MLGLDNAGKTTILKKFNGEDINTISPTLGFNIKTLEHRGYKLNIWDVGGQKSLRSYWRNY FESTDGLIWVVDSADRRRLQDCKEELDALLLEERLAGATLLVFANKQDLPGALSADKIRE TLDLDNIKSHHWLIQGCSAVTGDNLLQGMDWIIKDISSRIFTMD---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------EEAFYTTDRVMTVSFPKY GEYFPXTGDLRDIGAGRGRYYAVNFPLRDGIDDESYQTIFQPVMAKVMEMYQPSVIVLQC GADSLSGDRLGCFNLTLKGHGKCVEFMKRYNLPLLLLGGGGYTIRNVARCWTYETSVALN VEVANELPYNDYFEYYGPDFKLHISPSNMANQNTTDYLDKIKTRLFENLRMIPHAPGVQM QDVEEDAVKDDRKPGSRISICAHDKRITCDEEFSDSDDE----------------ENGTF ECNICLDTARDAVVSMCGHLFCWPCLHQWLETRPTRQVCPVCKAGISREKVVPLYGRGST NQQDPRDKVPPRPAGQRSEPENTTNFPGFGFGLHFSFGIGAFPFTFFASTLNLNDGRPQ- ------------------------------------------------------------ ------------------------------------------------------------ ------KEIDAGPVDAWTVCFSPDSRFLASGSHLGKINLFGVESGKKESELDTRGKFTLS IAYSPDGKYIACGAIDGIINTFDMTVGKLLEGHAMPIRGLCFSPDSRLLVTASDDGHIKI YDVQHANLAGTLSGHGSWVLNVNFSADNIHFVSSSSDKTVKVWDSGSRTCVHTFYDHTDQ VWSATYNQAGTQIASVSEDRAIHIYNVPV--------RYEAAFNDPNTDGWLIRKLMNDL HGYDLVPEPKIIIAAMKACRRVNDYAMAVRYLEAVKFKCDKNLDKIWPWMLQEIGPTXKE LGIDTPEEXGYDKPELAKADVFD------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GHSVHMRGLPFAATEQDILDFFKPLNPVNVVIH YNNGRASGEADVDFATHEEAKEAMKKDRSSMQHRYIELFFQDKDKPTQIRYSNITAAKAV ADAIRTSLGPRGMDKMIQADKGDVTITNDGATILKQMQVLHPAAKMLVELSKAQDVEAGD GTTTVVVIAGSLLDAAQKLLEKGIHPTIISEAFQKAAEKSVEILEEMATPLELSDRESLL KSATTSLNSKVVSQYSNTLSPLCVDAVLKVIDPAKDTNVDLHDIKLIQKLGGTVEDTELI EGLAFNQKTAGFGGPHLIEKAKIGLIQFCISPPKTDMESQVIVSDYTQMDRVLREERQYI LNIVKQIKKAGCNVLLIQKSILRDAVNDLALHFLAKMKIMVVKDIEREDIEFVCKTLGCR PVASLDHFHSDVLGSAELVEEVPVGESKIVKITGIANQGKTVSILVRGSNKLVLEEAERS IHDALCVIRCLVKKRALIAGGGAPEIELSLQLMKYANTLSGIEQYCFRGFADALEIIPFT LAENAGLNPISTVTELRNRHAQGEKTAGINVRKGAITNILEENVVQPLLVSTSAVHLAAE TARSILKIDDIVNCMMILLEIQNRIVEDTLTLKFNNALAGNRPDIVDISIADFDGVQYHI SNPDQDRTKLMVSISLKFYKELQEHGADELIKREYGPFLTTPEKGYSVSLLFDEKLPSNH EEVVKKVALLKRNCFASVFEKYFKFQQNQKKAVIHYRDDETLYVAAKTDRVTVIFSTQFK EEDDVVIGKVLLQEFVEGRRHQQQAPQVLFNYKEPPLELQNTDARTGDRIGYVTFVLFPR HDAMDNTINMIHTLRNYIHYHIKCSKAFIHTHMRAKTSDLLKILNRARPE-QVKDKKTIM LMFCPTCANVLVVEEGSTCYRFACNTCPYIYNVTKKISNRKYPKLKEVDDVLGGSAAWEN VDSTEETCPKCSHKRAFFMQIQ------------------------KKVFGPLKDEDRIF TNLYGRHDWRLKGALKRGDWYKTKEIILKGHEWIQGEIKKSGLRGRGGAGFPTGMKWSFM NKPSDGRPKYLVVNADEGEPGTCKDREIMRHDPHKLIEGCLVAGSAMGACAAYIYIRGEF YNEASSMQIAIKEAYDAGLIGKNACGSGYDFDVYLHRGAGAYICGEETSLIESLEGKAGK PRLKPPFPADVGVFGCPTTVNNVETIAVAPTICRRGGDWFGALGRP--LDVMMDFDALVE VNSALGTAALIVMNKSADIVSCIARLMEFYKHESCGQCTPCREGVSWMNSILQRFVTGNA RPDEIDLLQEISKQIEGHTICALGDGAAWPAQGLIRHFRPELERRMKEYHEKEFTQEQVD EMNQQLNQTRSQRVRAAMFPETLEEGIQIPSTQIHPDQPTAVQRLAEPSQMLKHAVVNLI NYQDDADLATRAIPELTKLLNDEDQVVVSQACMMVHQLSKKEASRHAIMNSPQMVAALVK S----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -MSADVQWMILRNNSSFLVKRHQFSTEPNNLRNRNSRRYNGLINRKTVGIEPADDGKGVV LVMRSGWRKPAKNYNRIELKHDARRNLSTIRRVIRKGRYRKDLKMAALRRASAILRSQNE TV-----DEPYYCAEQINIPPELPDILKQFTKAAIRTQPKDVLAWSAAYFRAMANGEMPP VKERLEMPTATQKTDTGLTPGLLRILNKQLGPKKIVSLSLIEEKWRSLALPMEQFQELVR IGNFGGDIEWLK-FALGCSTLGDNLTSTMKTVCEILTADPDGGPARIPFPLFQELYKYLA GIDGEISSEHINSVINYLTYQVDKQDGFIQPRNFLAADCPSLSXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXMNRLFGRAKPKGPPPNLNDCITNIDSRAESVDKKISRLDQELAKYKDQMKKMR EGPSKNMVKQKALRVLKQKRMYENQREQLSNQSFNMEQSNYAIQSLKDTKVTVDAMKVGV KEFKKEYKKINVDQIEDLQDELEDLTEQAGEIQEIMGRSYGMPDIDDAELEAELDALGDE LALDEDTSYLDEASTAPNAPTSVPGADSTTNKDGVPVDEFGLPQIPAQMTPLNPATPASP TLQNIVCTVNLCCKLDLKKIALHARNAEYNPKRFAAVIMRIRDPRTTALIFSSGKMVCTG AKSEEQAKLAARKYARIVQKLGFPTKFMDFKIQNMVGSCDVKFPIRLEGLVLTHGQFTSY EPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKVRQEIYDAFENIHPILKGFKKQ----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------KKNNQSIIFXDNQKDLENATEQLSEYLERD ITDDMLVDIKQKVQDEYRYCESRRKVLLDHVHEGYEK-------XXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGFSPR GGGGRFDRGGRGG--------GRGGGRGGRGGMAGGRKVIVEPHKHEGVFIARGKEDALV TRNLVPGEAVYGEKRIAVEDGTKVEYRAWNPFRSKLAAAILGGVDNIHMKPGSKVLYLGA ASGTTVSHVSDIVGPEGLVYAVEFSHRSGRDLINVAKKRTNIIPIIEDARHPHKYRMLVG MVDTIFADVAQPDQARIVAINAHHFLKTGGFIVISIKANCIDSTAEAEAVFAGEVNKLRA EKMKPKEQITLEPYERDHAVVVAQYRPPPKKMDKNKLNDLAGRLQRGGKGAGVGLGFLAA AGGIAYGLYQSLYTVEGGHRAIIFSRLGGIQPDIYKEGLHFRVPWFQYPIIYDIRARPRK ISSPTGSKDLQMVNISLRVLSRPDATMLPQMYRQLGTDYDERVLPSICNEVLKSVVAKFN ASQLITQRSQVSLLVRRELTERARDFNIILDDVAITELAFGREYTAAVEAKQVAQQETQR AQFIVEKAKQERQQKIVQAEGEAAAAKMIGEAISSNPGYLKLRKIRAAQNIARTIAASKN RVYLNAGSLMLNVNEPSFDENLD------------------------------------- ------------------------------------------------------------ ---------------------------------------------------LDDGGDATH LMLKKYPAMFKMVKGIVEESVTGVHRLYQLSKAGKLSVPAMNVNDCVTKTKFDNLYSCRE SILDALKRTTDIMFGGKQVVICGYGEVGKGCCEALKGXGAVVMVTEIDPICALQACMDGF RVVKLNEVVKNVDVIITCTGNKNVVTREHMDKMKNGCIVCNMGHSNTEIDVNSLRTPDLT WERVRSQVDHIIWPDGKRIILLAEGRLVNLSCSSIPSFVVSITAATQALALIEMYNAPNG RYKQDVYLLPKKMDEYVASLHLPAFDAHLTELSDEQAKYLGLNKAGPFXPNYYRY----- ---------KDMTEDEIKEKFEEYGQVEFVRLLKDRRSGESRGLAFVKF----------- ------------------------------------------------------------ ------------------------------------------------------------ ---------LAGGTLGGIVTVYVGQPLDTVKVKMQTFPSAYRNSLHCFVKTFKDSGSKGL YAGTVPSLENAILFVAYGLCQKLISCASFFSSLALCPTELVKCRLQVLIKHIIRQEGIRG LFHGLNATFAREMPGYFFFFGGYETCRTLLTPVDKTK-----RLLICGGMGGVAYWVSIF PTDVMKSRIQVKEEGVVALYKGLGPTVVRTFCATAALFYSYEKS-----AEYSNFNELVD IISSNIFTINNNGSILERALKQIGTSQDCVQLRNKIHTTEQKTNDVINDTVQSLRRLAKT STSNRQQKVQHGRLSSEFQDTVKRYNTLQKKVAEKVKSSVIEVEVALLQEREQHIRQLES DILDINEIFRDLGTLVHEQGVVVDTIESNIERGNVESGTEQLERAAAYQRKARKKMCCII AIVVVVLAVIALIIALSVK----------------------------------------T HLFLASDVIDSLQNIIDDFMDKINFPVSKKGGKAPTPQEAIQKLREVEEMLSKKSDFLEK KIEGELAIARKRVALTALKRKKRYEKQLQQIDGTLSTIEFQREALENASTNTEVLSVMGG AAKXLKQAHKNIGCXNVHNLMDDIAEQQE------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------SIFIFNPRTGQLYLKXIHTSV WAGQKRPGQLAKWKTAEEVAALIRPXPRKKTPKQIIVTRKGMLDPLEVHLLDFPNIVIKG SELQLPFQACLKVEKFGDLILKATEPQMFLFNLYDDWLKTISSYTAFSRLILILRALHVN NDRAKMTLKPDKTTITEPHHIWPTLSDEEWMKVEVCLKDLILADYGKKNNVNVVSLTQSE IRDIILGMEISAPSAQRQQIAEIEKQTKEQSQLTATTTRTVNKHGDEIITSTTSNYETAT FSSKTEWRVRAISATNLHLRTNHIYVSSDDIKETGYTYILPKNILKKFIIISDLRAQIAG YLYGVSPPDNPQVKEIKCIVMPPQWGTHQMVHLPSTLPNHEYLKTMEPLGWIHTQPNELP QLSPQDITTHAKIMADNQSWDGEKTIVITCSFTPGSCSLTAYKLTPSGFEWGRQNKDTGN NPKGYLPSHYEKVQMLLSDRFLGFFMTPATSSWNYNFMGVRHDPNMKYDLQLANPKEFYH EIHRPSHFLNFSSLEEGADRENLYSIYVRTRPNLTINKDTKVICQGFTGKQGTLHSEQAI EYGTKVVGGVSPGKGGKTHLGLPVFNTVHEAKEATNADASVIYVPPQFAAKAIMEAIDAE IGLVVVITEGIPQHDMVRVKNRLMQQDKTRIVGPNCPGIIKPGECKIGIMPGHIHKAGNI GVVSRSGTLTYEAVYQTTQVGLGQSLCIGIGGDPFNGTNFVDCLDVFLKDPNTDGIVLIG EIGGQAEEKAADFLTENNGPNYKPVVAFIAGLTAPPGRRMGHAGAIIAGGKGGAQEKIEA LKAAGVHVSMSPAQMGSTMYKAMEKVGKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFTRFVEIGRIAYVA FGPDEGKLVAIVDVVDQNRVLIDGPCSGVPRKVINLKQLHLTKFVIFAHNARTRVVRRAW EKAEIDKKWAETTWAKKIANREKRTKLTDFDRFKLMKAKQARNRIINTQFGKLRKAMAKT CPLLLRVFCNTGRHHMLSEYARGNTPANELQIYTWMDATLKELMSLVKEVNVDARRKGTY FDFAIVTPDIRSPVYRMNEIGSTCAGMKGKDDSVTLASKRFQIGDYLDIAITPP------ ------------------------------------------------------------ ---------VCVTSYEMVIREKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVRDFRSTNR LLLTGTPLQNDLHELWSLLNFLLPDVFNXSEDFDAWFNTNSCFENTQLVERLHAVLRPFL XRRLKSDVEK-VYLKKETKXYIGLSKMQREWYTXILMKDIDVVNGAGKSDKMRLL----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------SELQDIERIMAQIERGEAKIQRRISIKRALDAKMARYRAPFHQ LRIQYGTNKGKNYTEEEDRFLVCMLHKLGFDRENVYDELR-------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------DDDPLSKLKVSCRICKGDHWTTRCPYKDTLAPIQDVLSRPGKYVPPN LRDGGNRRGETMAPDDTATIRVTNLSEDTRETDLQELFRPFGSIARIYLAKDKNTGQSKG FAFINFHRKEDAERAIAGVSGFGYDHLILNVEWAKPS-------LLKVVLLGDGGVGKSS LMNRFVSNKFDSQSFHTIGVEFSNKDITVEGKMFTLQIWDTAGQERXKSLRTPFYRGADC CLLTFSVDDRQSLQNLSMWKKDCRYXDSEHFPFVVLGNKIDI-SEREVPTEEAEVWCHTN QMPFYETSAKDAINVDNAF----------------------------------------- ------------------------------------------------------------ --------------------------------KVTGCLIVCIERATRLVKSQQSAGKEYV CIFRLHSAVENEKKLAAAITTLTGALFQRPPLISAVKRQLRIRTIYESKLIEYDNQKNMG ILWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGIQSEMDGLVTMHDVLDAQWLYD HHKDESYLRRVIKPLEALLVSHKRIVIK-------------------------------- ------------------------------------------------------------ ------------------------------------------------XXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXX------------------------------------------RVTAAIASSIW SAFEKTGQSAFAEDGLDFILMECMDGKVAITKVANLLLCMYAKENVGLGMLRAKAKALAD YLEEPLTQVAAS------------------------------NPEERKRYTDYEFECXKP ASYLKXKESSVRRRYXDFDWFTXELERDSKDLTLHLPGKAWSKXLPFX------------ ----------------------------------------------CCVSSRLAEVGVLE DPKLQGKYDTGQLFLHKVFGYRGVVLFPWVGKIYDRDEETSSSKEIKARAHTYYQVLVDG RDIPHIRVGAETVTFLSNQGNGTLYSIPGLDYVSHEDVLPYRTTEKQPIHNHLFDKFLVT DPNYTARDSLRDWQDKNHPWLELTDVHRETTENIRVTVMPFYIGVVQQQHVYWWRYCIRL ENLGEETVQLRERHWRIFSLSGTLETVRGRGIIGKEPVFSKAQPAFQYTSHISLQAPSGH MWGTFKMEREDSSTFECRIPPFSLESKQEDGMAVSKGANTYNRQNWEEADFPILCQTCLG DNPYIRMTKDKFGKECKICARPFTVFRWCPGARMRFKKTEVCQTCSKLKNICQTCLLDLE YGLPVQVRDAALKIQDEMPKSDVNKEYYTQNMEREIAQTDGTTPVGAVGKAMAPSDMLLK LARTTPYYKRNRPHICSFWVKGECKRGEECPYRHDKPTDPDDPLADQNIKDRFYGINDPV ADKLMRRYNSMPKLEPPDDMDVFLMIRRKKTTIFMDAKESTTVMELKKMIQGIVKKKPED MKLFKDMKTLGDCGFTSSQARAQAPATIGMAFREFEHLEISPLSPPPELPDVMKPQESAS -HTQEHLYRYHAVLLRARFDENKYEDILKAKRLLEEGEAELQKYHHPQPIKFPNSPGGVA YGREVTAPDWCLDMWHPLERAQYPEYFKRREQRKLEFIENWEKKYGKPEMDDYIKIEKIG EGTYGVVYKGRNKKTNKTVALKKIRLESEEEGVPSTAIREISLLKELQHPNIVCLEDVLM QENKLYLVFEFLSMDLKKYLDTIPSGQFMDKMLVKSYTYQLLQGILFCHQRRVLHRDLKP QNLLIDSKGVIKLADFGLARAFGIPIRIYTHEIVTLWYRAPEVLLGSQKYSTPVDIWSIG CIYAEMVTKRPLFHGDSEIDQLFRIFRTLTTPTESTWPGVSSLPDYKSTFPNWKTNTLSQ SVDAAGLDLLQSMLIYDPAKRIAAKDALKHHYF--------------------------- ------------------------------------------------------------ --------------------------------------------------------QVSQ QINEELMNRATQFGIMLDDISITHLTFGREFTEAVEMKQVAQQEAEKARYVVEKEEQRKK AAIIRAEGDSQAAVLLAKVLSEAGEGLVELRKIEASEDIAYQMSQSPNVIYLPPGQQTLL SLP-KTIKANQSVAIPKGVEVKIKSRKVVITGPRGTLRRNFHHMQVDIRKF-KNHILVEK WFAIRKELAAVRTVCSHIENMIKGVMKGYKYKMRSVYAHFPINITVLENNTVVQIRNFLG EKYTRNVRMLPGVTCTPSEKQKDEF-------------XALIHQSTKVKNKDIRKFLDGI YVSEKGHVEEDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XX-------------------------KKRKPNPQNLTVREIPQVSSALFFRYNTQLGPP YHVLVDTNFINFSIKNKLDIVQSMMDCLYAKCIPYITDCVMAELEKLGRKYRVALRIAKD ERFQRLPCLHKGTYADDCLVERVTQ----------------------------------- -----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX--------------------------------------------- -------------------------FLFNMIFTYRYCRMLEEGSFRGRTADFLFMFIFGG TVMTIVVNLVFLGHAFTIMLVYIWSRRNPYVRMNFFGLLNFQAPYLPLVLLGFSLLLGNS VIIDLMGIAIGHVYYFLEDVFPEQPRGFKVLRTPAILKYLFDPVPDDPNYNPLPPGGFEW GQ---------------------------------------------------------- ------------------------------------------------------------ ------------------SATLAVIDAGLPMKDYITACSASIVNDIPIVDINNFEESAGL EILIAILPKSSQIVFMEMNGKLHEDHLEKVIDTAMMGSSDVYDILDQAVRDMAGNYYFVI VAQYDNPIFEMEFAPLNKANDPKRDDHRHLNQFIAHAALDHVDEQMWTTNNMYLKIIDKF NEWFVSAFVTAGRMRFVMLHDMKNEDGIKNFFQDTYETYVKYSMNPFYEPNTAIRSPAFE KKIQVYGRKYLTSQIRLAHTDIKIPDFSAYRRDSTKDARRAFTYMMLAAGTVPTLYAGKA LAAEFVLSMSATADVLALAKVEVNLADIPEGKNAVFKWRGKPLFVRHRSADEVAREEAVD INILRHQETDQERVKRPEWLVTIGVCTHLGCVPIANQGEYGGYYCPCHGSHYDASGRIRK GPAPLNLEIPPYEFTPSNTVIIGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXENVKAFLAQAKXDFLKKWEDPISNNAGFXDFDRIKAL GTGSFGRVMLVQHKNTKXYYAMKILDKQKVVKLKQVEHTLNEKRILQAINFPFLVRLEYS FKDNSNLYMVLEFVTGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHPLDLIYRDLKP ENLLIDSQGYLKVTDFGFAKRVKGRTWPLC------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------SNSRDLSLVKMKSMFATGFAFTALLGMFNSIFDGRVVAKLPFVPI SLLQSISHRNLIGDDYTDSSFIFLYILCTMSIRQNIQKLLGFAPSRAANKQGSGLFSAXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXQDGETNADRNVEIWKIKKLIKSLEAARGNGTSMISLII PPKDQISRVAKMLADEFGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVIYCGT IVTDEGKEKKVNIDFEPFRPINTSLYLCDNKFHTEALTALLADDSKFGFIVMDGNGALFG TLSGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAEVAVQLYITNDRP NIAGFVLAGSADFKTELSQSDMFDPRLQAKVIKIVDVSYGGENGFNQAIELAAESLANVK FIQEKKLIGKYFDEISQDTGKYCFGVEDTLKALEMGAVEILIVWENLEIMRYVLKNHQTD EEKVLFLKPEQEKDKTYFTDKKTGVEMELVESMALLEWFANNYKNFGATLEIITDKSQEG AQFVKGFGGIGGILRYQVDFQSLEPLDDIDETFDLDDY---------------------- ------------------------------------------LVFLDIHNIHVMRXSLRK LKEICFLPXDDAHWLSQIESTSWLTHIKQXLAGATRIVDKVENHKTSVLVHCXNGWDRRQ LDSVSACCMLDPYYRTITGFEVLIEKEWISFGHKFQMRIGHGEDKHSDTERSPVFLQFID CVWQISHQFPHAFEFNEQFLLIILDHLYSCLFGTFLYNTDKMRHEEKVKHRTVSLWSYIN SQLDEFINPLYQGVLQPVPSMRRLNLWRGYYLRWNPRMKPQEPIHLRYRELLALKAQLQQ RLEELQKQVEAQN----------------------------------------------- ------------------------------------------------------------ -----------------EELKQTDPHEVLTMLTNESGFEISSSEATVKVLVTTIPPNLKK LDSELHVXGKIMQGHLAAIRHARWFEENAFHSSIKVLIRLLRDLRNRYDGFEPLTPWIID LLAHYCIMNNPTRQPLPIQIAYKRVFHLLAAGFFLPGSAGITDPCEQGNVRIHTVMTLEQ QDQVCCTAQTLLRVLSHGGYKQVLGIEESGDIDTSMSVWEGIVVTPSEKAYEK------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -QAQDNFMMMDDAVLCMSFSRDSEMLSTGSQDGKIKVWKIQTGQCLRRFERAHAKGVTSI TFSRDNGQLLTASFDQTIRIHGLKSGKTLKEFRGHTSFVNDAVFAADVQHIISASSDGTI KVWNMKSTECLNTFKSFGGTGGSDITVHSIHPLPRNTEQFAVCNRSNTIVLMNMQGQIVR SFSSGKREGGDFVCACLSPRGEWIYCVGEDLVLYCFSLQTGKLERTLTVHEKDVIGIVHH PHQNLIATYSEDGLLKLWKPMAQAVTKVPVLIDASVPRLQTVWKYAKVELRPPGELPEVR KGFNDLVQYRTQKWKQVTVKEATIVAVEVACWFAIGECIGKRSLVGYQIPGAVDFEAH-- ------------------------------------------------------------ --------------------------------------------FNYVMRKVWLHQTRIG LSLYDVAGQGYLKESDLENYILELIPTLPQLDGLEKSFSSFYVCTAVRKFFFFLDPLRTG KVKIQDILACSFLDDLLELRDEDLPKDMQECNWFSAPSALRVYGQYLNLDKDHNGMLSKQ ELAKYGTGTLTSVFLDRVFQECLTYEGEMDYKTYLDFVLALENRKEPQALQYLFRLLDIE NKGYLNVFDLNFFFRAIQEQMRFHQQDPVSFDDVKNEIFDMVKPADPYKITLSDLIKCGQ GDTVVSILIDMNSFWTYENREXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXX------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------QAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLLFILAD VPLPLGTITILCIDLGTDLVPAISLAYEQAESDIMKRLPRDPQHDKLVNHRLIGVAYGQI GMLQAASGFFTYFVIHCEHGFWPSRLLGIRKQWDSKGVNDLEDSYGQEWTYAQRKVLEFT THTAFFMSIVIVQWADLMICKTRKNSIVHQGMMNHHLTFGLFFETALAAFLAYCPGLDKG LRMYPLRFTWWLAPMPFSLVIFIYDEVRKYLLRKYPGGWVEQETYYSFKTLSKGKKIAAG VAAGA----VALQELVLHPPAFPWNHKGVFDSYDHASVRRGYQVYKQVCAACHTMDFMYY RNLVGTIMTEDEAKAEAAEIQVVDGPDDEGNMFKRPGKLADRFPQPYANEEAAKVANSGA LPPDLTFIINAREGGADYIFSLLTGYWDLPAGCEEREGLHYNPYFAGGYIAMAKALYNDI VEYDDGTPATASQLAKDITTFLAWTAEPEMDERKRMGIKTMVILLLFFSFYYKRVKWLPM KTKK--WTHPGLPSRCTYQKGIPAKSPHSCVKRVPKVLPNVLYKIGETPLIKINKIGKSY GLECDILAKCEFFNAAASVKDRIGLRMIEDAERSGLLKPGDVLIEPTSGNTGIGLAVVAA VKGYRCIIVMPEKMSMEKVNMLRALGAEIVRTPSDASFDSPESHIGVAHRLLQEIPNSHI LDQYRNPSNPLAHYDGTAEEILEACDYSVDMIVCGTGTGGTITGLSRKIKEKCPDCKVIG VDPYGSIMAEPMDIQSYEIEGIGYDFVPTVLDRQLISKWYKSTDKESFQMARRLIHEEGL LC----------------------------------------------------MSNAES DEETGVYLGEYEGERNERDERHGHGKATLPNSDTYEGMYENGKRNGQGTYRFKNGARYIG EWLKNKKHGTGTFIYTDGSKYEGSWVDDQRCGFGKYYYINGDTYEGEWQNHVRHGQGTYV YAETGTKYTGTWKDGKREGQGELIHANHKYVGPWKDDRTEGKGKYVFDIGCMQHGEY--- ---------------------------------------------------------WLR RMAVHRRFRGKGIAGKLIQTAIDFCRDHEYKKICLITTDVHVQARQLYQKYGFICKSYKP IFYLNGL----------------------------------------------------- ------GHVLYNKEDATKGKFAFTTEEYDMFEVCFETHMIAGGHGADREVYLHMKHGVEA KNYQDIAKAEKLKPLEVELKKLEDLAESIVNDFAYMRAREEEMRDTNESTHSRVLYFSIF SMXCLLALATWQVL---------------------------------------HGNLDWX KICEQASKVITFXDLAGHERLFKTTVFGMTGHAPDFSMLMVGANAGVIGMAKEHLGLXLA LNVPVFVVVTKIDMCPPNVLQETLKILQRLLKSPGCRKIPVLVQSVDDVVVSATNFSSER MCPIFQVSNVSGENLEPVKXFLNLLSTRLC-MSQQNSIDDTFSVPXVGTVESGTTLRGEI HLNDTLLLGPDLLGXFMPIAVKSIHRKRXPVKEVRRSDSHQFALKKTDQRKGMVMLSPKL EPKACWEFEGEILVLHHPTTISVKYQAMVHVGSIRQTATIMSMSKEHLRTGDKAMVRFRF IKNPEYLRTDMRMVFREGRTKAVGTVTKLFPHVSLNTRQQRASKKAVE------------ ----------------------------------------------LLFGHTDRVMAVCY ---YNGLLATGSDDHTVRIWDCSTGQCLTVIQTHT--VAEVKFNS--FIFTASFDTTAAC WDFLNHYTGHVAAVFSIDYSTSLDTVITGSADSTIKVWHQLIQTLPHHRS---------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------GDVFMEKHWKSVIHRSICDYFFEAQSKASSPEDVPPIISTPHH YLINIYRNQLYVVAVVTTEVPPLFVIEFLHRVMDTFEDYFGECSESNIKDNYVVVYELLD EMLDNGFPLATESNILKELIRPPNILRTITDTVTGKSTTVSDTLPTGQLSNVPWRRTGVK YTNNEAYFDVIEEIDAIIDKSGSTVCAEIQGYIDCLVXIVGMPDLTLSFVNPRLLDDVSF HPCVRFKRWESERILXFVPPDGNFRLISYHIGSQNMVAIPVYLRHTISFKDGSNGRLDIT VGPKQTMGKTVENVLIEIPFPKTVLNVTLTTNQGKYSFDPVTKLMTW------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------KEVIEGIKKQLQTKIDESFEQLCVLQEARQQILADLQ DKNIALGIDVDQYNLTEESPTISFKPDPLRVPKGSTTPQQWEDFSRYNKERADAEMANSK RLREAIHHTLQQTENDLEAQHTATDYATRKRIHEFERAIDELNWQKQQTEEEIAELEEDI RRLNDAIRAKINPLKLAQTRLENRTYRPNVELCRDNPQYGLTDEVKQLEASKRALEEKLK QSQHALDGLEQNLHRINEDLQTKMNSLRLDQQCMAAREKL----------------AAEI PEQIREIKEFRAKHNNTVVGDVTVDKVYGGMRGILGLATETSLLDPEEGIRFRGLSIPEC QKLLPSAPGGSEPLPEGLFWLMVTGKVPSEGQVKALSKEWANRADLPSHVVTMLNSFPAN LHPMAQFSAAIIACNSESKFAKAYAEGVKKAAYWEYTYEDALDLIAKLPTIAAIIYRNLY RDGTSVGAIDPNKDWAANFVSMLGYEDPQFVELMRLYLTIHADHEGGNVSAHACHLVASA LSDNYLSYGAGMCGLAGPLHGLANQEVLIFLTKAMYTSDQLKEFVWKTLKSGQVIPGYGH AVLRKTDPRYTCQREFALKHLPDDPMFKLVSDLYKVVPDILLELGKVXNPWPNVDAHSGV LLQYYNMMEMNYYTVLFGVSRALGCMASTIWDRALGLPIERPKSITTQALMKKV-MPFQP PKTEKCATCGKSVYAAERMEAGGNVYHKLCFKCATCKMPLKLNNYQQNEGKLLCKTDYQK EILAKNAQIDKIFVHRDTPDNNPDIPFEFNNENLKRAKAIIGNYPEGHQSAAVLPLLDLA QRQHGWLPISAMHYVADMLKMPRMRVYEVATFYTMFNREPVGKYHVQVCTTTPCMLGGVG CGPILEAIKKQLGIGVGQTTPDKMFTLSEVECLGACVNAPMVQINDDYYEDLTENDIIEI INDLKAGKKPKAGPRSGQNGRFASEPKGGLTSLKEPPYGPGFKVRADLMLKYEKLEKIGE GTYGTVFKAKNKETHEIVALKRVRLDDDDEGIPSSALREICLLKELRHKNIVRLYDILHS EKKLTLVFEYCDQDLKKYFDSCNGEIDPDVVKSFMYQLLRGLAFCHGKNVLHRDLKPQNL LINKNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGGKLYNTSIDMWSAGCIF AELANAGRPLFPGNDVEDQLKRIFKLLGTPTEETWPGMTQLPDYKQYPMYYVNQQVVPKL NAKGRELLLSLLVCNPTKRMSADDAMQHGYFSDLNPSVR--------------------- ----------------------------------------RGGRGVIKTKKKQEEQRICV ARAPRGKRKFVTIVTGLTTCGIDLKVASKYFASKFSCGSSVTGEDELVIQGDVKDELFDV IPEKWPQIDEDNIDDLGDQKR--------------------------------------- -------------------VQFPELRLIEYDCGKLQTLDVLLARLKVGGHRVLIFTQMTR MLDILEQFLSYHGHRYLRLDGTTKVEQRQILMDRFNMDKRIFCFILSTRSGGLGVNLTGA DTVIFYDSDWNPTMDAQAQDRCHRIGQTRDVHIYRLISEMTVEENILKKANQKRLLGDVA IEGGNFTAAFFKQQTIKEL----------MSLETVPKDLRNLRACLLCSLVKTIDQFEYD GCENCEEFLHMKNNRDAVYECTSSNFDGVISLMSPEDSWVAKWQRINRHVKGVYAISVTG RLPPGIISDLKSKGIIYRPRDFSMPRFVPYLSKEQEDELRKIANAIAAPGKGILAADEST GTIGKRFSQINVPNEEDNRRHYRQLLFTSLGQYISGVILFHETLYQKADDGTPFVKLLQD SGIIPGIKVDKGVVPLAGSDGECTTQGLDGLAERCAQYKKDGCGFAKWRCVLKIQSHTPS LQAMIENANVLARYASICQQNGLVPIVEPEVLPDGDHDLETAQKVTEQVLSFVYKALADH HVFLEGTLLKPNMVTAGQSCSKKYSPQEVALATVTALQRTVPPAVPGITFLSGGQSEEDA TIHLNAINQKPWALTFSYGRALQASVLKAWQGKSENVKAGQAELMKRALANSQAALGQYK GGEKGAAAESLFVANHAY------------------------------------------ ------------------------------------------------------------ -----MIQEHDEPILKHLQDVKVNFQVGFTLEFHFSPNEYFTNHVLTKEYIMRCEPDEND PFSYEGPEIIKCKGCKIDWNKGKNVTIKVIKKAQAHRGRGTKRIVTKTIQRDSFFNFFNP PDVPEGTASEDTEAILGADFEIGHFLRERVIPRAVLYFTGEALEEEEENDEEDEDIILLK EGTDTSQGKPQLISNISACQAVVEAVATTLGPRGMDKLIVDSNGKATISNDGATIMKLLD IVHPAARTLVDIARSQDAEVGDGTTSVVLLAGEFLKECKPFIEEGVHPQIIVRAYRKAAN LIVQKIKEIAIKVEKDPKEQRDLLTKCAATALSSKLVATQKDFFAKMVVDAVMSLDELLP LNMIGMKKVQGGAIEDSQLVMGVAFKKTFSYAGFEMQPKKYNGPKIALLNIELELKAEKD NAEIRVDNVKEYQAVVDAEWTILYNKLEKIHLSGAKVVLSKLPIGDVATQYFADRDMFCA GRVQDEDLKRTMYACGGSIQTTVTSITLGTCEMFEEKQIGGDRYNLFTGCPKAKTCTIIM RGGAEQFIEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIAGKEQLL IGAMAKALEVIPRQLCDNAGFDATNILNKLRQKHAGTWYGVDINNEDITDNLIACVWEPS VVKINALTAASEAACLILSV------------------------KRNNVVPNAHFHKDWQ RYVKCWFNQPARKKRRKNKRIEKARKIAPRPLH-TLRPVVRCPTLKYNTRLRLGRGFTLD ELKQAGLNKHQAKTIGISVDYRRRNRSVESLQQNVQRLKEYRSKLIVFPRKMSQPKKGDA TEEEMKMATQVLGNIMPIRETFKKEKARAITDKEKKFSVYVAIRQARADVRLVGVRAKKA KEAMPNIKVFSGNSHPDLAQKIADRLGIELGKVVTKKFSNQETCVEIGESVRGEDVYIVQ SGSGEVNDMLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSPISAKLVANMLSVA GADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENIPEWRNGIIVSPDAGGAKRVT SIADKLNVDFALIHKERRRANEVAAMVLVGDVKNKVAILVDDMADTCGTICHAAEKLLEA GATKVYAICTHGILSGPACSRINSSMFEAVVVTNTIPQDEKLKNCSKLQVLDISSIMAEA VRRTHNGESVSFLFTQVPILSCRFYEHRFPKIEDVVMVTVRSIADMGAYVKLLEYNNIEG MILLSELSRRRIRSINKLIRVGKSECVVVIRVDEDKGYIDLSKRRVSQEEIARCEEKFAK AKCVNSILRHVGELLNYDSDEQLETLYKNTAWHFDKKYGKPGAAYEAFKRAVTNPEIFEE CDLDSKTKTVLVDNIKQRLAPQSVKIRSDIQVSCYAYEGVDAVKNALRAGLNLSTEEMPI KINLIAPPSYVVVTQTLDRTEGMARGQQKIQAQQKNAAKQAALKSDQKKAAQAALTHQCP VCKTKMPDPKTFKQHFESKHPKSPLPDELKDI---------------------------- ------------------------------------------------------------ ---------------------------------KDGKAYCRDDYFNMFAPRCAGCNQPIM DNFISALNRQWHPECFVCYECHMPFGSTSFFDHEGYPYCETHYHAKRGSLCAGCHKPITG RCITAMYKKFHPEHFVCAFCLKQLNKGTFKEENDKPYCHPC------------------- --------------------YCFRLNNERVYYCSEELMKRAANISRDNLINLGTCFGKFT KTRKFRLHITALDYLAPYAKYKLWVKPSAEQQFLYGHHVMKSGLGRITESTPQYQGVVVY SMSDLPLGFGVTAKSTTD---------------------------ADQRKFFVGGNWKMN GNKASIDEIIKFLNEGNPNTEVVCGPPTIYLDYVRQKLIGVAAQNCYKVEKGAFTGEISP AMIKDIGVNWVILGHSERRHVFGETDQLIGEKVAHALAAGLHLIPCVGEKLEERXAGKTE EVVFRQMKASDWSRVVIAYEPVWAIGTGKTASPEQAQEVHVAIRKWLETNVSADVAKSTR ILYGGSVNAKNCKELAKKPDIDGFLVGGASLKPEFIDIINAKDREGLLDPAWERQQKKTF TAWCNSHLRKAGTQIENIDEDFRNGLKLMLLLEVISGEQLPKPDRGKMRFHKIANVNKXL QFIESKGVKLVSXGAEEIVDGNLKMTLGMIWTII-------------------------- -----------------FDVAEKYLDIPRMLDAEDMVNSVKPDERSVMAYVSSYYHAFSG AQQAETAANRICKVLEINQENERLMEEYERLASDLLEWIRRTTPWLEDRSTDNTLPGTQR KLEEFRDYRRLRKPPKLEEKAKLETTFNTLQTRLRLSNRPAYIPTEGKMVSDIASAWKGL ERAEKGF----------------------------------------------------- -------XFESDLAAHQDRVEQIAAIAQELNTLGYHDCASVNARCQRICDQWDMLGSLTQ QRRHALDEAEHILERIDQLHLEFAKRAAPFNNWMDGAKEDLVDMFIVHTTEEIQGLMDAH EQFKQTLGEADKEYNAIMALVHEIQRISQQYGIQNALENPYSTLQANDIAHKWREVQQLV PARDSTLQTEMIRQQNNERLRRQFASKANVVGQWIERHLDAVASIGMQKGKLEEHLNKLR GIEREVNAFRPNMDELEKYNEEVQEAMIFENKHTPYSMETLRVGWEQLLTSVARNINEVE NQILTRDSKGISNEQMEEFRKSFFHFDKSRSRRLEPKEFKACLISLGYNIRDDHQGEADF QRIMSIVDPNHLGYVTFDAFLDFMTREATDNDTAE------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------EVEAACADPAPGSVILLEILDPH-EEEGKGVDADGXKIKADPA KIEQFRASLKKLGDVYVNDAFGTAHRAHSSMIG-QHGQKAAGFLLKKELTYFAKALENPE RPFLAILGGAKVADKIPLIENMLDKVNEMIIGGGMAFTFLKVLRNMEIGKSLFDEEGAKI IQKLMDKAKTNNVQIHLPVDFVTGDQFSADAKVGMATVESGIGPNEMGLDVGPESNAKFT EVIGRAKTIVWNGPPGVFEFENFQKGTKAMMDAVVHATEKGPLXIIGGGDTATCCAKFKT EDKVSHVSTGGGASLELLEGKVLPGVAALSDAMAGIPPKSWQPPNVTLETTMGTIVCELY WKHAPNTCRNFAELARRGYYNGIKFHRIIRDFMIQGGDPTGTGRGGASIYGKQFEDEINS ELKHTGAGILSMANSGPDTNGSQFFITLAPTQWLDGKHTIFARVCGGMNVVSRIGMVETD NNDHPTEDVKILRRRSRDRTRERKRSPE-KKKPYKYWDVPPVGFEHMTPMQYKALHGLIP FAGSAISRQARRLYVGNIPFGVTEEMMMDYFNTQMKMAGLAQAEGNPVIACQVNLDKNFA FLEFRSVDETTQAMAFDGINFQGQSLKIRRPKDYQPLPGMAEVPSVGVVSTVVQDSAHKI FIGGLPNYLNEDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYLDQACAGLNGMQLG DKKLIVQRASVGAKNAQVLQVQLQIPGLNMAQVTTEVLCLMNMVAPEELEDEEEYEEILD DVKEECSKYGYVKSIEIPRPIKGVEVPGVGKIFVEFNSVIDCQKAQQALTGRKFSNRVVV TSYFDPDRYHRREFFLPMFDRVLVQRFAAETRTKGGVLIPEKAQSKVLHAKVVAVGAGAR NDKGETVPLQVKVGDQVLLPEYGGTKVVIDDEELHLFREGDILGK--RLKSQIPDISTTL NIVKHMQSKKEPMQTHFQMSDSVFVAATVPPTDKVCLWLGANVMLEYNLDDAEALLKKNV AIKGLEQVEEDLGFIRDQTTTIEVNMARVYNWDVKRRQAATSMADEALARAGLHFDELNK IRVLEPEIATQTTELKEETKEFLDKIFEFQXIVNSFISLIDNVAEEVEKEKMKAIGSRNL LKSVAQQRQAQQQELQALITEKRIQLERLRIQYESLLKDEQEQSDFIEQFILQKXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX EEEKDEESPSPMQRPKQRTRRGAVSAEVYTEEDAASYVKKVVPKDYKTMAALSKAISKNV LFSHLDDNERSDIFDAMFPVHRHAGEVIIQQGDEGDNFYVIDQGEVDIYVNGEHVNSIGD GGSFGELALIYGTPRAATVKARTDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLSKVSIL ENLDKWERLTIADSLEPVQFDDGQEIVKQGEPGEDFFIIVEGTASVLQKRAENEEPIEVG KLGVSD-FGEIALLLDRPRAAT-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------YLAPHVTTLYAQIRNRGLC QYFSPYLSADMHKMASAFNTSVLALEDELMAPILEGQINARIDSHNKILFAKDVDPRSWT FEKSLAMGKEYQRRTKALILRSAMLKNQIHVKSPPREGGQGGEMTIVPGNAASXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXRHTVTLMAGDGVGPELMTHVQEVFHHAGVPVDFEEVQ LDRNGVAIKGNVETAVTSRNLALRAELDLYANVVCCKSVKGVETRHNNIDLVVIRENTEG EYRQLEHENVPGVVESLKIITAKGSNRIAKYAFEYAVRHGRKKVTAVHKANIMKLGDGLF LECCHQMSKNYPDIEFDSIIVDNCSMQLVSRPQQFDVIVLPNLYGNIIANIGAGLVGGPG MVPGLNVGEHYAVFETGTRNTGRHVAGKNIANPSAMLLAAGDMLSYLGLEYHGNLVHEAV NSVLGDSKFHTPDIGGTALTTDVVSEIIRRI-DDFLRFMDRSTRIIERAIWEEVDIFVDY SGADDDQGLAEGEKLKLNRQFYDERWSRHRIITSLDWSVQHPELLVASYNNNEDAAHEPD GVALIWNIKYKKTTPEYIFHCQSAVMSACFAKFHPNLIIGGTYSGQIVLWDNRSNKKTPV QRTPLSAAAHTHPVYCVNMVGTQNAHNLISVSNDGKVCSWGLDMLSQPQDSMELIQKQSR VAVMCFSFLSGDVNNFVVGTEETVVCTACRHGSKAGITDVFEGHQGPVTGIDCHAVPGQI DFSHYFITSSFDWSVKLWNIKDNKPLHSFEDNNDYVYDTRWSPIHPALFATVDGMGQLDL WNLNNDTELPTATTVNVALNKCRWHQGGHNIAVGDDYGRVYIYDVGETLAQPKSDEWSKF VHTLQDLQTTKADQEEE-IQNQLLHATNIIEQQVDAEIDRLDHMGEDDYEALRKKRLQQL KKAQQQKQEWLSQGHGKYEEIADEKEFFSVCKKSKNVICHFYRDSTFRCKIVDKHLMLLA PKHIEARFVKINAEKCKFLVDRLHIVVLPTLCLAKDGKTVDYIVGFDDLGGKDDFPTEML EWRIARADVISYSGDLLTPPVAKKQKKTIQQKDDND------------------------ -------------------------------------CSGKVSRVGTDVTKWKIGDRVLS LRTFQSQQ--HDLVSIENMPWEEGSAVCLTYGIAFYVVNDLMMVRADEIVHITDCSSRIG EACAWL------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------------MS RKQTPSDFLKQITGRPVVVKLNSGVDYRGVLACLDGYMNIALEQTEEYVNGQLKNKYGDV FIRGNNVLYISTQKRRIMSQEQSALLLRRQLAELNKHPVDGFSAGLIDDDDIYRWEVLII GPPDTYYEGGFFKTHLTFPRDYPLKPPKLKFITEIWHPNIDKTGDVCISILHDPGEDKFG YERPEERWLPVHTVETIMVSVISMLADPNDESPANIDAAKEWRERREEFKKKVARCVRKS QETTVRKPNPVIRSNLMDFGQYVGECLPRFVQKVQVTNGNELEVMIHPDGIIPVITFLRN HSHAQFLNLTDIAGVDVPSRKFRFEIVYNLLSVAYNARIRVKTYTDELTPIQSIQPIFKG ANWYEREVWDMFGVFFANHPDLRRILTDYGFEGHPFRKDFPLTGYVEVRYDDEVKRVVVE PLELAQEFRKFDYSTPWESFPNYRES---------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------GDPC TQGPGMVVDDELKHPIRSHHDIEKDNCKYMKKAMKHYEALANRAANNGHCVDLYACALDQ TGLHEMRYLPTYTGGHMVMGDSFNTSLFKQTFQRVFAKDQKNEFKMALXANIEIKTSKEL KLQGCIGSCISLNVGANVSDTELGMAGTTQWRMCGLYPTTTYAFYFEVVSQHNAPIPQGG RGYIQFITQYQHSSGQKRVRVTTVARNWVDASINTQHVAAGFDQEAAAVLMARIASFRAE TDDGPDVLRWLDRMLIRLCQKFGDYHKDDPNSFRFSEQLSLYPQFMFHLRRSQFLQVFNN SPDETSYYRHKLLIEDLTQCLIMIQPILYAYSFNGPPEPVLLDTSSIQPDRILLMDTF-- ------------------------------------------------------------ ---LSKVNPSQTHNNMYAEGGGHVLTDDVSLQVFMEHLKKLAVSSSSMSNLSHEEQLKLI QDLEIEMMADMYN--SAACQKKCVPPRYKEADLSKGEAVCLDRCVAKYMEIHDRIGKKLT DVSMQDKETVQKIQA---------------GGVGKSALTLQFMYDEFXEDYEPTKQIHIR KRXILDGDDVQIDFVGLVAAIRDNYFRSGEGFLCVFSXQNRNPFRQQSEFREQILRVKND ENIPFMLVGXKMDLEDKRQVTVEEAQSRAQQWNVPYVEXSAKTRANVDKVF--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------TPRMTFECFRR FYLGKHSGRQLSLQPQHGSADLNAVFYGAKKDAVDSKTAARKHIIQVSTYQMVVLMLFNN RDKWTYEEVKTETDIPERDLMRALQSLALGKMTQRVLTKEPKTKEIEADHVFQVNEHFTS RLFRVKXQTVAAKGESEPERKEKGSKVDEE------------------------------ ------------------------------------------------------------ ------------------------KKIIETKTLMGDVMKEAAFSLAEAKFAMGDFNDLVI QNVSKAQIKVKSKKDNVAGVFLPIFEHYQDGSDSYELTGLSRGGQQIDKLKRNYAKAVEL LVELASLQTSFVTLDETIKVTQRRVNAIEYVIIPRIERTLSYITQELDEREREEFFRLKK VQNKKQRDKPTSMLDDYDEDLLFPLRVCVTGAAGQIAYSLLYSVAKGDVFGPNQRISLVL LDIESMMGVLEGIVMELVDCALPLLAEIKPTANVSEAFKDISVAI--------------- ------------------------------------------------------------ ------------------------------------------------------------ --------AAASHAAAVTSLLHHWWCGSPQGQIFSLGVYSEGYNVPESLVFSFPVTFPGY WSVVQDIDLTDEAKSQIELISKDLLSEKE------------------------------- --------------------------------------------------------SALV LELLGPSLEDLFDLCDRKFTXKTVIMLAIQLITRMEYVHSKHLIYRDVKPENFLIGRQSN KKQHIIHIIDFGLAKEYIDSETHKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEAL GHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATAIEVLCENFPEELGTYLRYVRRLD FFETPDYDYLRKL----------------------------------------------- ------------------MTTIRPFTCDDMFRFHNVNLDPLTETYGLPFYMQYLAHWPEY FKVAESPSGEVMGYIMGKAEGHAENWHGHVTALTVAPDFRRLGLAAKLMNILEEISEKKH CLFVDLFVRVSNQVAVDMYKRLGYSVYRRVLDYYSGEEDEDAFDMRKALSRDVNKQSVIP LPHPVRPEELXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMDGDFEPVDEPLDEVQKQPNVEIVS QTEKVDPDKRMTTPYLTKYERARVLGTRALQIAMCAPVMVELEGETDPLAIAMKELKARK IPLIIRRYLP----------------KKLTLKERAMAPAGDGAFTAGKGMLAGVSALGLG MLCYYGLGMSNQVGAIDRAAIWPNIVRQRVKDTYMYFGGSLIFTAASRSPVMMRLVMRNG WMTLIGTMAAMIGSGMIVRSLPYKEGAKQIAWMIHSGIVGAVIAPITLLGGPLMIRAACY TAGVVGGLSALAMCAPSDKFLYMGGPLAMGLGVVIVSSLGGMFIPPTTALGAGMYSVALY GGLALFGMFLLYDTQKIIYRAENHPVYAVQPYDPINNSVGIYLDTINIFIRIATILAGGG GNRR-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------KQDITKAQGAMALEYEPTIPTKFMVGTEQGSILSCNRKAKTPAEKIVA LYPAHYGPVYALQRNPFFPKNFLSIGDWTARIWSEDIRESSIMWTKYHMSYLTDGCWSPV RPAVFFTTKRDGTLDIWDI----------------------------------------- ----------------------------------------------------------IA KPMASRKLAKKIYKVIKKALRKGIRDVQKFVRKGEKGVIIIAGDTSPIEVVCHMPLVCEE GEIPYCYTPSKEDLGSACGSRRPTCMVMIKAHESYQELYDTVHEEVKGLPLPI---ENLE EQGLVKNPNLEIAQWKFLLGTDRHKNDQKLKNDLLQIIKENDMAPYYELVCADLSWSVDQ ALLEKMKGANLAKLKELDNAIEDAEQNLGETEVRDFMLKKAEYLSKIGDKEAALTQFRKT GEKTVTLGFRLDMVFHQIRLGLFYMDHDLIKRNLEKAQSLIDEGGDWDRRNRLKVYRGVY SMSIRDFKMAANLFLDTVATFTSYELMDYKHFVSYTVLCSMIALERPKLREKVIHGSEIL EVLHSLPNIKQYLFSLYNCQYSDFFKSLALMEQEMKHDRYLSPHYRYYTREMRIHAYSQL LVSYQSLTLDYMAKAFGVTPAFIDQELSRFIAAGRLHCKIDKVGGIVETNRPDSKNYQYQ ETIKXGDILLNRIQKLSRVINI-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------GRLTGLSSQSTXRVGNALGMIGVSXG IAATIGMLKPEMDVLAQMLGCMGVGATIGTIAAKRIEVTDLPQMVALFHSLVGAAAVLTC IANYMAEFSHFATDPAANITKTSLFLGTYIGGVTLTGSLVAFGKLQGLLKSDALLLPGRH PMNLGLLLGNVGAMGLFLKSGDNTGLAMLGTTTALSSIMGITLTMAIGGADMPVVITVLN SYSGWALCAEGFMLNNNVMTIVGALIGSSGAILSYIMCKAMNRSLPNVILGGYGTSSTGT GEAMKVTGVHKEIFPDETVEQIAEAQNI-------------------------------- ---------MPGQLNVLLAEAGVPYDIVHEMDEINDDMPEVDLTLVIGANDTVNSAAEED PNSIIAGMPVIRVWLSKQVIIMKRTLGVGYAAVDNPVFFKNNTSMLLGDAKKTCDTLLAK TKMQRPESIPGCPPGLEYLSQIDQLLVHQQVELFEVLTNWETRNRYQIKNSVGQQVYFAQ EESDTCHRQCCGPQRGFSMHITDNLGQEVIKVIREFKFCAGCNCCAGCSMEIEIQXPVGQ VIGYXKQQCLAPKYSVNDAVLMIQGPTCICQGPCCTSDQEFIVYSHEVGKISKQWSGFVK EYFTQADNFGVSFPMDLDVKIKAVLIGAVFLIDFMFFENKNN----ELQQFLQLEQQRAL FHSQIHRLMDLCWDQCVDKMRDKMDSKTETCFTNCVERFVDTSLHITNRFQQMLQRGM-- ------------------------------------------------------------ ------------------------------------------------------------ LPGETWNPLKLKYQLRNVRERLXKNLVEKGVCSTEKQNFLLFDMTTHPLTDNQIKSKLVK RVQDSVLSRWVNDPHRMDKRMLALIYLAHASDVLENAFAPLSDDDYEVAMKRVRELLDLD FEQETMKEGANELMWAVIAAFSKAKKITEVNEENCEVCVKFMMKFIDNLDKIENEFRKLC KKAKKSENRFCYYIGGLEESATSILGEMSKPVSWGMPADKVCMKIYRKDEQICDLKYEKT IDFATVDLKKLKVKDLKKILEDWDTVCKGCTEKSEYIQLIEDLMPQYAPEAAXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXMPKVVSRSVVCTDT-DQEEYQGEKPLYVYYCLCGQMSLILDCPLE KLPLRK---ARVIDSNKHAHKLTCEPDETVYLKSQXGIERQYRQKCKKCXLWLYYRHRNQ VTFIIDGSLET------------------------------------------------- ---------------------------------------------VSRQCMRVAANQQMR GYADMSFTFASPAAVNVKQVDVPSFSGSFGILPNHVPTLAVLKPGVVTVIEEDGTSKKYF VSSGTITINDDSSVQILAEESAKVEDLDIDAIRDGANKAAQDLTSEQAKAEAQIAVECYE ALQKALQCKYFTTELLSRLEET-ESKEIIRTGHGLDRKKEFPYKYSELRLTEALLEPHVC DRILGYNVHAERKGSLRYAKGQSETMATLHGLVNKGVKVDLGIPYELWDSPSAEVTKMQR KCFKLAEDYEEDIEEWYFNQQVDLTKFLCVDRYLK-----FSPTDVTSEEDVKTAMVAKK QFGGLHVAVNCAGIGVAVVTYNAGKDRVHKLEEFQRVINVNLVGTFNIIRLAAQLINENE PNADGQRGVIINTASVAAFDGQRGQAAYSASKGGVVGMTLPIARDLASRGIRVNTIAPGL FDTPLLGELPEKVRKFLATSVPFPQKLGVPDEFAHLVQFLVENPMMNGEVIRIDGGIR-- ------------------------------------------------------------ ----------------------------FFDTIKGSDWLGDQNAIQYMCEEAPKAVIELE NYGMPFSRLDDGSIYQRAFGGQSLDFGRGGQAHRACCVADRTGHSMLHTLYGRSLMYDTD YFIEYFATDLLMENGQCKGVMAISLEDGNIHRFRANNTVLATGGYGRAYFSCTGAHTCTG DGTAMVTRAGLSNMDMEFVQFHPTGIYGAGCLITEGCRGEGAYLINSEGERFMERYAPTA KDLASRDVVSRSMTMEIREGRGVGPEKDHIYLQLSHLPPEQIQARLPGISETAHIFAGVD VHREPVPVIPTVHYNMGGIPTNYTGQVIQTDGVDKEVPGLWAAGESACVSVHGANRLGAN SLLDLVVFGRACANTIAERFKPGDKLPDLSSNAGEESVANIDKLRHANGGITTADLRLRM QKTMQNYAAVFRDGPTLQEGCKRLGKLYEELDLKLSDRGMVWNSDLIESLELQNLMLNSL QTAHAAENRKESRGAHAREDFKKREDEYDYSKPLEGQKPRPLEKHWRKHTLTHVDLSSGK VAISYRPVIDKVLDPSKVETVPPKVRSY-------------------------------- ------------------------------------------------------------ -----CQENAWLRDELANTQQKLQQSEQKVATLEEEKKHLEFMNQMKKYDMEGSLGFPDD DEDQQQSAMAQAASGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHD HPDVATMLNILALVYRDQGKYKEAANLLNDALGIREKTLGPDHPAVAATLNNLAVLYGKR GKYREAEPLCKRALEIREKVLGKDHPDVAKQLNNLALXCQNQGKYEEVEKYYKRALHIY- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------GMMIGGVRHVADIRADDMDKEG QSIIGLQAGTNKGASQSGMRIGGVRHIADIRADDMDKEGQAIIGLQAGTNKGASQSGMMI GGVRHAADIRADDYDDSAAVISLQMGTNKGASQSGMRIGGVRHVADIRADDVEGAAVIGL QMGTNQGASQAGMRMGAQRHIADIRADDMSSAGVINLQYGTNQVANQSGMAFGGRRDIMP ETHHFGAVAIYTHSWSGNRSYLALSSSNTVDLYKVNFQKANTLDAHTQSVTGIDWAPKSN RIVTCSADRNAYVWHSMVVLRINRAATCVKWSPQENKFAVGSGAKVVSVCYFDSSNDWWV SKHIKKPIRSTVTCLDWHPNNVLLAAGSSDFKARVFSAYVKEVEEKPGQTVWGSKMPFGN LMAEFSSGGGWVHDIXFSGNGDRLAWVGHDSSLSVVDATYKTPFLPFVTCTWVSPKRLVT AGHNCEPMLFEFDGKSIKLVKKYDTNVISARKLFKNMDSKAQKLKTIHQNSITKLSIHSG TKDQCKKFSTTGLDGMITVWD--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------EECRDFKKTVLNEIAQHKIKIYEFEDEEEAKLQKKLKDRV PFAVVGSNTVVDSSGRKVRGRVYPWGTVEVENLEHNDFIALRNMLIRTHMQDLKDVTNNV HYENYRYNKLVSVTKSPLLQLEEERKEHDAKMKKMEAEMEQVFEMKSKKKKNK------- --------------------------------------MSRRYDTRTTIFSPEGRLYQVE YAMEAIGHAGTCLGILAKDGVILAAEKRNTNKLLDEVSYSEKIYKLYDDMACSVAGITSD ANVLTNELRLIAQRYMLQYQEPIPCEQLVSQLCDIKQLYTQFGGKRPFGVSLLYMGWDKH YGFQLYQSDPSGNYGGWKATCIGNNSGAAVSMLKQEYKEQEVDLQAGLELVIKVLSKTLD TNKLTPEKVEIATLTRENGKTKIKIVPDSELE---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ 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------------KEGEKLIEEGNHNXDSIRQRCENLHKNFEALLESANXRKARLIDNSAF LQFIWKTDVVESWIADKXTQVLSEDYGRDLSSVQTLLTKQETFDAGLQAFEKEGIQTITA LKDQLIAANHAQTPAIEKRYNHVITRWQRLLSDSEDRKQRLLRLQEQYRQVEDLYLSFAK KASAFNSWFENAEEDLTDPVRCNSVEEIQALREAHEQFKASLKTAEEDFNQLASLDQQIR SFNVGPNPYTWFTMEALEDTWKNLQKIIQERDEELAREQQRQEENDMLRKRFAQAANQFH QWLTDTRSAMMEGSGTLESQLEATKRKAAEVRAQRSQLKHIEDLSAAMEERLILDNRYTE HSTVGLAQQWDQLDQLGMRMQHNLEQQIQACNQSGVSEDALREFSMMFKHFDKDKSGRLN HQEFKSCLRALGYDLPMVEEGQIDPEFEAILDVVDPNRDGMVSLQEYMAFMISRETENVQ SSRDVEAAFRALAAGERPYITGNELYSNLTKEQADYCIAKMKPYEDPRGRVIPDAYDYVA FTRELFIN-IQCYQCDSNEDYSCPSYRIFDRNINALVDCNSFEAKTPGTFCMKITQQSPG WGAWKKVTRRCGSRSESGVAWGCQWDFEENGVWREVCYCEDRDGCNGASNIDRNDTDNPQ LVSEYVNDIYDYMRELESRIINGRMRGILIDWLVQVHLRFHLLQETLYLTVAIIDRFLQV SVARNKLQLVGVTAMWIASKYEEMYAPEVGDFVYITDNAYTKADIRKTECIMLKALDFSL GRPLPLHFLRRNSKAGEVDASQHTMAKYFMELTITDYEMASTPPSKVAAAALCLSMKVLE WNDTLQHYSKYTEEDLQPIMERIALLVTKKLTAIKTKYQSSKFMRISQMPELSSQLILDL AXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX >Pedicellina_cernua XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----RQMQTSSQRMDIDQAAKYIGAGAATV GAAGSGAGIGNIFGNLIIGYARNPSMKQQLFSYAILGFAMSEAMGLFCLMMAFLILYAFM SHYKEAGKAPEAQIHRIRITLTSRNVKSLEKVCADLIRGAKDKRLKVKGPVRMPTKTLRI TTRKTPCGEGSKTWDRFQMRIHKRIIDLHSPSEIVKQITSISIEPGVEVEVTIADMDQVS XXIDPMKLFFKDSFRLVKKCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNII VMSNQKSKKRKFVADGVFKAELNDFLTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVL GEKGRRIRELTSVVQKRFGFADGSVELYAEKVAQRGLCAIAQAESLRYKLIGGLAVRRAC YGVLRFIMESGARGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPVNDYIDSAVRHVLLRQ GVLGIKVKIMLPWDPLGKNGPKKPLPDHVSIVEPKEETPITEPYSEAKGVKXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXX-------VKLGPQVMDGENVFGVAHIFASFNDTFVHITDLSGKETIVRVT GGMKVKADRDEASPYAAMLAAQDVAERCKVLGITALHIKLRATGGNRTKTPGPGAQSALR ALARAGMKIGRIEDVTPIPSDSTRKKGGRRGRRLMGKPSGLRTARKLRNHRRDQRWADND YKKAHLGTRWKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP NDGCLNFIEENDEVLIAGFGRKGHAVGDIPGVRFKVVKVAGVSLLALFKGKKERPR---V ATIRTRKFMTNRLLCRKQMVVDVLHPGRATVPKTEVKDRLGKMYKTTGDNVFCFGFKTQF GGGKTTGFALIYDSLDAAKKFEPKYRLQRAGTRKQRKERKNRQKKVRGTKKTKVGSMPRI PCVVSKTYKTPRRPFEKERLDHELKLIGEYGLRNKREVWRVKYLLAKMRKTARILLTLDE KDPRRLFEGNALLRRLVRIGVLDEEKMKLDFVLGLKTEDFLERRLQTQVFKLGLAKSIHH ARVLIRQRHIRVRKQVVNIPSYVVRLDSQKHIDFSLKSPFGGGRPGRVKRKNAKKGTGGG GGMGSAFAKLFSGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIGEAREELNRMLNEDELRD AVLLVFANKQDLPNAMNAAEITDKLGLHSLRNRQWYIQATCATSGDGLYEGLDWMSNQPK NSKMPLAKDLLHPSYEEEKRKCKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRRKQHMVRMNVLADCLKSICNAEKRGKRQVLIRPSSKV IIRFLTVMMKHGYIGEFEVVDDHRAGKIVVNLTGRLNKCGVISPRFDIKIGQVEKWTTNL LPSRQFGYLVLTTSGGIMDHEEARRKHLGGKILGFFFMGRMHAPGKGISQSALPYRRSIA TWLKLSSDDVKEQIFKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKAKGLAPQ IPEDLYHLIKKAVSIRKHLERNRKDKDSKFRLILVESRIHRLARYYKTKSVLPPNWKYES ATASALVAVAEIPEIKLFGKWSTEDVEVSDISLTDYIAVKEKHAKFLPHSSGRYQVKRFR KAQCPIVERLTSSLMMHGRNNGKKLLTMRIVKHAFEIIHLLTGENPLQILVQAIINGGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREAAFRNIKTIAECLADELINAAK GSSNSYAIKKKDELERVAKSNRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXX-------SSEHVNLKVVGQDGSTVHFKIKKNTQLRKLMN AYCDRTGVQMKAVRFMWDGQPLSETNTPSTLDMDNDDSIEVFQQQTGGMATLPMNPKPFL NALTGKPVMVKLKWGMEYKGYLVSVDGYMNLQLADTEEYVDSAFSGNLGEILIRCNNVLY IRGVDEEAEEGEAHDMSDNEGD-APAAPAPGAAMDINTALQEVLKTALNHQGLVRGINEC AKALDKRQAHLCVLSQKCEEPSYVKLVEALCAEHSIHLIKVEDNKKLGEWVGQCTPDKDG KARKVVGCSCAVVKDYGKDSPALDVLQEYFKSK-MAAIRKKLVIVGDGACGKTCLLIVFS KDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSI DAPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEQVRCELATMKQEPVALDQGRQ MAERISAFGYLECSAKTKEGVREVFEMATRAALQVKKRRKAKXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFSGTAKIXXXVGEKPDEFESSISQ ALLDLEMNSDLKAQLRELYINGTKEVEVSGKKAIIIFVPVPQLKAFQKIQTRLVRELEKK FSGKHVVFIAQRRILPKPTRKSKRKNKQKRPRSRTLTAVHEAVLDDICYPSEIVGKRIRV KLDGSRLIKVHLDKSNQTTVEHKLDTFSGVYKKLTGKDVTFEFPEYVL----------GR GRGRGRGRGRGGKEEKEWVPVTKLGRLVKESKIKTIEDIYLFSLPIKESEIIDFFLGPVL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDSNGHVGLGVKCSKEVATAIRGAIILAKLSI IPVRRGYWGNKLGKPHTVPCKVTGKCGSVLVRLIPAPRGTGITAAGVPKKLITMAGIEDC YTSATGQTATLGNFAKATYQAIAATYAYLTPDLWPDLPFQKAPYQEFTDFLAKXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXMKFNKMVTSSRRKNRKRHFQAPSHIRRKIMSAPLSKELKQKYNVRAIPVRKDD EVQVVRGHYKGQQVGKVVTCYRKKFVIHIERIQREKANGASVHVGIHPSKVVITKLKLDK DRKRILEKKARSRQHGKHTEESI----------TLRQRKTGGTQMGSAGMWKFYSEDSPG IKVGPVPVLVMSLLFIAFVFMLHIWGKYQR-KKEKKGKSTMTEVVTREYTINLHKRIHGI GFKRRAPRALKEIRKFTEKMMGTVDNRIDTQLNKHIWSKGVRSVPFRVRVRLARKRSEDE DSVHKLYTYITHVPVETFKGLSTKNVESXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNPEKLKQRIGGKGSARRKKKVVHRTATTD EKKLQNTLKKLGVNNIPGIEEVNMIKDDGSVIHFNNPKVQASLAANTFAVTGHAENKQIT EMLPTILNQLGPENLQSLKKVAAET--IDEGDEDVPELVGNFDEPSKDEMGRYSLDPENA SKSAKAKGSHLRVHFKNTRETAQAIKKMHLKRAVKYLKNVMIKKECIPFRRFAGGVGRCA QAKAFGATQGRWPKKSADFLLQLLKNAESNAEFKGLDTDHLYIEHIQVNAAPKMRRRTYR AHGRINPYMSSPCHIEVIVSEKDQPIPKGVKKKVSQKKLKKQKMMMREXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXX---------KRRKTGGRRPQPRKKRKYELGRPAASTKIGA SRIHTVRTRGGNKKYRALRLDHGNFAWGSEGCTRKTRVIDVVYNASNNELVRTKTLVKGA VILIDATPFRQWYEEHYATGLARKKNAKLTEEEEARLNARSKKTAKKYEERKKTAAVDHS LEEQFGSGRLMARISSRPGQTGFCDGYILEGRELEFYMKKIKSKKGRMSLVVPEKFQHIL RVMNTNIDGRIKIMYAMTAIKGVGRRFSNLVLKKADVDLRKRAGELTEEEVEAVVTIINN PKQYKIPNWFLNRQKDVKDGKYNQVTSNGLDNKLREDLERLKKIRAHRGLRHYWGLRVRG QHTKTTGRRGRTVGVSKKKSSGDESGSEDGMPDLEEVAQAAGLQEELVSKAKQSRSEKKA RKAINKLGLKQIPGVSRVTIRKSKNILFVINRPDVYKNPQSDIYIVFGEAKIEDLNQQAQ MAAAEKFRNEGEVDESGVEVKDIDLVVSQANVSRAKAVKALKNNSQDIVNAIMMGRVRTK TVKKAARVIIEKYYTRLTLDFHTNKRICEEIAIIPSKRLRNQIAGFVTHLMKRIMKGPVR GISIKLQEEERERRDNYVPEVSALDEVDTDTREMLKFLDFGQIQNLQPTQPIVSGMKWQY KEDHTYDRRRSEGERMRRKHPDRIPVIVEKAPKARLGGLDKKKYLVPSDLTVGQFYFLIR KRIQLRPEDALFFFVSSVIPPTSATMGTLYQEHQDEDCFLYIAYSDESVYGMRDLRIQKL CLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVRSFGIRRNEKISVHCTVRGPKAE EILESGLKVKEYELRRNNFSDTGNFGFGIQEHIDLGIKYDPGIGIYGMDFYVVLNRPGMR VTKRRRRPAKLGFGHRVQKDEAIKWFQQKYDGIILPGK---------------------- -------------------------------------------RVIMASNRGTLMELGIS PIVTSGLIMQLLAGAKIIEVGDSPKDRALFNGAQKLFGMVITIGQAIVYVMTGMYGEPSQ IGAGICLLIIIQLFIAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVN TGRGTEFEGAIIALFHLLATRNDKVRALREAFYRQNLPNLMNLLATVVVFGVVIYFQGFR VDIPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSAKFAGNILVRLLG VWEDVQGGGPSRSYPTGGLCYYLSPPETLSHVATDPVHAVLYIIFMLGSCAFFSKTWIDV SGSSAKDVAKQLREQQMIMRGHRDTSMVKELNRYIPPA------CIGALSVXXDFMGAIG SGTGILLAVTIIYQYFEIFVKEQSEMGGMSTLLFQTERAFQKQPTVFLNKKRLL-PRFSR SVGLGFKTPREAIDGSYVDKKCPFTGDVSIRGRILTGIVTKTKMQRTIVIRRDYLHYVKK YNRFEKRHKNISVHCSPCFRDVKAGDIVTIGECRPLSKTVRFNVLKINKTSGSNKSFSKF -VNVPKTRXXXCKGKKCKKHTLHKVTQYKKGKDSVVVQGKRRYDRKQSGFGGQTKPIFRK KAKTTKKIVLKMECSQCRYKKQLPIKRTKHFELGGGKKVKGQMIQFMGRVIRSQRKGPGS VFRAHTNHRKGAAKLRSVDYAERHGYIKGVVRDIIHDPGRGAPLAKVVFRDPYQYRQKME TFIASEGMHTGQFIYCGKKASLQVGNILPIGQMPEGTVICCVEEKFGDRGKVARASGNYA TVVAHNPDTKRTRVKLPSGAKRLVPSANRAMVGIVAGGGRIDKPILKAGRAYHKYKVKRN CWPKVRGVAMNPVDHPFGGGNHQHIGMASTVRRDASAGRKVGLIAARRTGRLRGTKTIDS KARRTKKVGIVGKYATRYGASLRKMVKRMEVSQHAKYTCQFCGKEAMKRSAVGIWKCKSC KKTIAGGAWVPSTTAAATVRSAVRRLREMKEMGRRPARCYRYCKNKPYPKSRFNRGVPDS KIRIYDLGRKKAGVDDFPLCIHMVSNEYEQLSSEALEAGRICANKYLVKNCGKDAFHLRI RVHPFHVLRINKMLSCAGADRLQTGMRGAFGKPQGTVARVNIGQTIMSVRSRDNIKDHVI EAFRRAKFKFPGRQKIYMGQNWGFTKWKRENYAKMRQDGILIPDGVNVQYKPNKGPLQAW ----KVTKVLGRTGSQGQCTQVRVEFLDDTNRSIIRNVKGPVREGDILVLLESEREARRL RMTKGTSSFGKRHNKTHTLCRRCGRSAYHIQKKRCGACGYPSQRIRKYGWSVKARRRKTT GTGRMRHMKTVFRRFKNGFREGTVAK----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGAYKYMQELWRKKQSDVMR FLLRVRTWHYRQLTGVHRATRPTRPEKARRLGYRTKQGICIYRVRVRRGGRKRPVAKGIT YGKPKTHGVNELKPQRSLQSVAEERAGRHCGGLRVLNSYWVGEDSTYKYFEIIMVDPFHK AIRRCPDLQWICSNKMKHREMRGLTSAGKKSRGLGKGHTFAKTTGGSRRAAWKKYNTQSM RRKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXMGFAENFMLSGAAAVISKTAAAPIERVKLLVQNQDEMLKMGRLDKPYSGVVDCTM RTFRNEGVLPFWRGNLANCLRYFPTQALNFAFKDSIKTMFKMKKSDPYVVNFSKNIASGG VAGAMSLCFVYSLDYARTRLANDAKSGSKRQFNGLVDVYRKTLKSDGIQGLYRGFVISCV GIVVYRGCYFGFYDSLKPILLGEDAGLMASFALGYAVTVTSGLISYPIDTIRRRMMMTSG EAVKYKGAVDCTVQIIKNEGFMSLMKGAGANILRGVAGAGVLAGFDKFKAVYMKWRLXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMQNDTGENVDM YIPRKCSTSNRIIAAKDHASIQMNIAEVDPTSGRMTGSFKTYAICGEIRRMGESDDSILR LAKRDGIVAK-VRGPRKHLKRLNAPKHWMLNKLGGPFAPRPSTGPHKLRECLPLVLFIRN RLKYALTYDEAKKIMMQRLIKVDNKVRTDICYPAGFMDVISIERTNENFRLVYDIKGRFA IHRISPEEAKYKLCKIRKVAVGPKGVPYVTTHDARTIRYPDPLVKTNDTVQIXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXMSERYSFSXXXFSPSGKLVQIEYALNAVAAGAPSVGIK ASNGVVLATEKKQKSILYDEHSVNKIECISKNIGMVYSGMGPDYRVLVKAGRKISQQYQL AYQDHIPSSQLVSRVAAVMQEYTQSGGVRPFGVSLLCAGWDKRPYLYQCDPSGAYFAWKA TALGKNHINAKTFLEKRYSDTLE--EDAVHTAILTLKESFQMTENNIEIGICNQD----- ---------------------------GGGAGGDKKDDKDKRKKYEPPVPTRVGKRKKRI RGPEAASKLPQVTPHTRCRLRLLKMDRIKDFLLLEEEFIRNQERLKPQEEKHEEERSKVD DLRGTPMSVGSLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDQLEPGCSVLLNHKVHAVI GVLGDDTDPMVTVMKLEKAPQETYADIGGLDSQIQEIKESVELPLTHPELYEEMGIKPPK GVILYGAPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEYALS IVFIDEIDAVGTKRYDSNSGGEREIQRTMLELL--------------------------- ------------------------------------------------------------ ----------------------------------------KRKPYSPFQVSNKAEYAVAR LDDLLNWCRKSSLWPLTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQADVIIVAGTL TNKMAPAFRKVYDQMPEPRWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPT AEALLYGILQLQKKIKRMKFVQSWYRKSEFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYA NNSQYKNDTMIRKEAYVHQSVMEELKRIIEDSEIIQEDDTSWPQPDRVGRQELEIVIGDE HISFTTSKIGSLVDVNNSRDPEGLRTFYYLVQDLKCLVFSLIALNFKIKPIMVAGKKSKK AIESINSRLALVMKSGKYVLGYRQTLKTLRLGKAKLIIIANNTPPLRKSEIEYYAMLAKT GVHHYNGNNIELGTACGKYFRVCTLAITDPGDSDIIRTMPT-XXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKIEVCY YSGXEIYPGHGKRFIRVDGKVHHFLSAKCAASHFMKRNPREIPWTILYRRKNKKGQTEEE KKKRTRRTHKFARAIAGATLQDLQAKRNQKPEIRKAQREQAIRAAKEKKRSEKSAAPKVG GKRMKLNISFPATGCQKLVEIDDEKKVRIFYEKRIATEVDASSLGDEWKGYVFRITGGND KQGFPMKQGVLTATRVKLLLSKGHSCYRPRRKGERKRKSVRGCIVDNTISVLNIVIVKKG DGEIEGLTNDTKPRRLGPKRASNIRKLFNLGKDDDVRQYVVRRPLTATSKAPKIQRLITP LTLQRKRRRVALKRRRAEKQREDASEYAKLLAQRMKEAKDRKAERKRSASHSRKVKAKDL RSKKREDLEKQLEELKQELSTLRVAKVTGGAASKVSKIRVIRKSIARVMTVCHQKQKENL RKVYKPKDLRPKLTRNLRRQLSPSERRMKTAKQQRKDRLYPMRKFAVKKKSSGPKVTDKV FFDIEIGGKKAGRIEIGLFGSTVPKTAANFKTLAEGSKTYKGSKFHRVIKDFMIQGGDFT RGDGTGGKSIYFADENFKLSHYGAGWLSMANAGKDTNGSQFFITTVKTSWQDGKHVVFGK ILKGMSVVRTIEKTSTQGDMPEKDVFIADCGSIPVDTPFSVDKKPADDKKKKIHHEFTLD CTHPVEDGILDVAQFEKFLVERIKVGGKTGNLKSKITVSADIPFSKRYLKYLTKKFLKKH SLRDFLRVVAHTKDSYELRYFNVNNEDDDDDGDD-------EEKKFGGCEGPDAQYVKLI SSDNHEFIVRRDHALTSGTIKAMLSGPGQFAENETNEINFREIPSHVLQKVCQYFTYKVR YTNSSTEIPEFPIAPEIALELLMAANFLDCXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX--------DDLKNVEFETSEEVEVIPTFDSMGIREDLLRGIYAYG FEKPSAIQQRSIKPIVKGRDVISQAQSGTGKTATFSISILQGLDTQVRETQALVLSPTRE LAVQIQKVILALGDYMNVQCHSCIGGTNVGEDIRKLDFGQHVVSGTPGRVFDMIKRRSLR TRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVCLISATLPHEILEMTSKFMTDPI RILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKM REANFTVSAMHGEMPQXERDAIMKEFRGGSTRVLITTDVWARRPDVQQVSLVINYDL--- ------------------------------------------------------MAMRRP FDPVALELDASFRLTKFADLKGGCKVPQEALEKLLEGLTSAQQEEQSHFQYGGEAPRIGI GMDSCVTPLRHGGLSLIQTTDFFYPLVDDPYMMGKIACANVLSDLYAMGVTDCDNMLMLL ACSNKMTDKERDTVVPLMINGFKDNAEEAGTKVEGGQTVINPWLTIGGVATSVCQINEYI MPDSAVVGDVLVMTKPLGTQVAVNVYQWLDVPERWSRIKLVVSEDDVKKSYQRATHSMSR LNRTAARMMHKYNAHGATDVTGFGLLGHANNLAKIQKNEVGFVIHNLPVIAKMAAVSKAC GNMFGLLNGTSAEPLGG------------------------------------------- ------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXTAPFDARFPNQNQTRNCWQNYVDFHRCQKVDDYA DCYYFKRVFRTLCPNAWVEKWDEQVEAGTFAGKI-KDYLGSDQRKVKDQEKDDAPIQALD EDDISLLKSYGQAQYSKKIKAVEKDIQDVLKRVNELSGIKESDTGLAPPALWDLAADKQT LQSEQPLQVARCTKIINADSDDPKYIINVKQFAKFVVDLGEHVAPTDIEEGMRVGVDRTK YQIHIPLPPKIDPTVTMMQVEEKPDVTYADVGGCKEQIDKLREVVETPLLHPEKFVNLGI EPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARA KKACIIFFDEIDAVGGARFDDGAGXDNEVQRTMLELINQLDGFD-RAYIKV--------- ------------------------------------------------------------ --------------------------------------------------DKTHINIVVI GHVDSGKSTTTGHLIYKCGGIDKRTIEKYEKEAAEMGKGSFKYAWVLDKLKAERERGITI DIALWKFETENFCVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKNGQT REHALLAFTLGVKQLIVAVNKMDNTEPAYSQARFSEIEKEVSAYVKKVGYNPKAVAIIPI SGWHGDNMINMKWWKGWEVANGFTLLDSLNAILPPSRPTDKPLRLPLQDVYKIGGIGTVP VGRVETGIIKPGIVVTFAPVNLSTEVKSVEMHHEALLEALPGDNVGFNVKNVSVKEIRRG YVAGDSKNDPPMGAKDFTAQVIVLNHPGQIHNGYAPVLDCHTAHIACKFAEIKEKMDRRS GKVLEENPKFIKSQDAAIVTLVPSKPMCVESFQQYPPLGRFAVRDMRQTVAVGVIKSVTK AEASGGKTTKSAAKAELETLRHEAEQLKNQIREARKAAADTTLAAAAASVDPVGRIQMRT RRTLRGHLAKIYAMHWALDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAP SGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDGQIVTSSGDMTCA LWDIETGQQTTAFTGHTGDVMSLSLSPNMRTFVSGACDASAKLWDVRDGMCKQTFSGHES XINXITYF---------------------------------------------------- -----------------------------------------------------XXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMSKINKDNLNESIALILSKKRKFTETVELQISLKNYDPQKDKRFNGTVKLRHVPRPK LRVCMLGDQAHCDEAKANNVDSMDAEALKKLNKNKKLVKKLAKKYDAFVASESLIKQIPR LLGPGLSKAGKFPSMLTHNESLMSKIADIRSTIKFQMKKVLCLSVAVGHVDMEQDELYHN VALSVNFLVSLLKKNWQNVRALYIKSTMGPSQRIYXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX----STVIARTVQRTLPKRHAPGAAFVAAHKFSTSAEVSSILEDRILGTTKADLEET GRVLSIGDGIARVYGLKNIQAEEMVEFSSGLKGMALNLEPDNVGVVVFGNDKLIKEGDIV KRTGAIVDVPVGEGLLGRIVDALGNPIDGKGPIEGAKRQRVGVKAPGIIPRTSVKEPMQT GIKAVDSLVPIGRGQRELIIGDRQTGKTAVAVDTIINQKRFNDAAEEKKKLYCIYVAIGQ KRSTVAQLVRRLTATDSMKYSIIVSATASDAAPLQYLAPYSGCAMGEFFXDNGKHALIVF DDLSKQAVXYRQMSLLLRRPPGREAYPG-------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEYAQVLKMLGNG RLEARCFDGVKRLCHIRGKLRKKVWINAQDIILIGLRDYQDNKADVIMKYTPDEARNLKT YGELPETVNITDADDVEIGYDGSDD-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPILIDGRGHLLG RLASIVAKTLLQGQRVVVVRCEAINISGSLYRNKLKYQDFLRKRMNTNPSKGPYHFRAPS KILWRVIRGMLPHKLTRGKEAMERLKTFEGVPAPYDKKKRMVIPAALKAMRIHPRRKFCT MDVLSHEVGWKYKSVIETFENRRKVRSSLFHKKKTAINRLREQATKIAPYQKIIEGYG-A GNPEKGRKTFVQKCAQCHTVEAGGKHKTGPNLNGLIGRKTGQASGFTYTDNNKNKGITWA SDTLFIYLENPKKYIPGTKMVFAGIKKKGERTDLISFLYKGT-XXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXMLMPKKDLICIYEYLFKEGCMVAKKDKFAPKHPDVDVKNLHVI KALESLTSRGYCKERFNWKHYYYFLTNEGIQFLREYLNLPPEIVPATLKRQADGDRRGEY RRGPPGDKKEDAGPGTQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX MTNTKGVRRGTRYMFSRPYKKGGVIPLSTYFKIYKRGDIVDVKGHGAVQKGMPHKVYHGR TGRIFNVTPHAVGVIVNKRVGGRIIPKRINVRVEHVKHSTCRLDFLRRVKENEKKMAEAK ATVTCKRIPAQPRKGHFVKTKFCSPQVIEPIPYEFIA----------------------- ------------------------------------------------------------ ----------------------------------------GFCQEACPVDAIVEGPNFEY STETREELLYNKEKLLANGDKWEAEIAANIQADHLYRXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX------------------------------------------- ------------------------------------------------------------ -----------------------------------IALSFWVFRNFSPTVNYVVSMGSVS GLIALLSTGSQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------------ ------------------------------------------------------------ ------------------------------FSKYMNGTKIAVFFGGLPITKDEEVLSKST PHIVVGTPGRILALGKTLNLKNIKHFILDECDRMLEALDMRRDVQEIFRMTPHEKQVMMF SATLSKEVRPVCRKFMQDPMEVFVDDDSKLTLHGLQQYYLRLRDNEKNRKLFELLDALEF NQVIIFVKSVQRCMALAQLLSEQNFPAIAIHRAMKQEDRLQRYQAFKDFQKRILVATNLF GRGMDIERVNIVFNYDMPEDSNTYLHRVARAGRFGTKGLAITFVCDESDAKIPPSYGDLG KKARDLFSKSYNYGFMKLETKTKTSSGVEFTVNGSTCTDTNKVNGSLETKYKCSEHGVTF TEKWLTDNVLSTEVSIEDQIAKGLKLTFDTSFAPQTGKKSGKIKTGYKREYMNLNCDVDF NFAGPIVHGAATLGYNGWLAGYQMSFDKSQLTRNNFAVGYDGGDFVLHTNVNDGQEFGGS IYNKPRKDLEVGVALSWSQGSAATRFALGSKYTLDENTSLTAKVNNLSQVGFGFQHTLRD DIKMTMSTLVDGKNLNQGGHKFGIGL----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXMLVLVLGDLHIPHRCANIPNKFKKLLVPGKIQHILCTGNLCTKES YDYLRTLATDVHVVRGDFDENPSYPEQKVVAVGQFRIGLCHGHQVVPWGDVESLAMVQRQ LDVDVLISGHTHKFEAFEHEGKFYINPGSATGAYNALDSEVNPSFVLLDIQQSTVVTYVY QLINEEVKVERIEFKKMGKFIKSGKVVLILGGKYAGRKGIIVKNHDEGTTEKPYGHALVA GIDRYPRKVTKRMGKKKQKDRSKMKPFVKVYNYNHLMPTRYFVIPLSKEVVNKDVFRDPA LKRKARREVKTRFEERYKQGKNRWFFSKLRF--TFIMVKPDGVQRGIIGDIIKRFEQRGF QLVAMKFMQADKALLENHYADLSKKGFFPSLVEFMASGPVVPMVWKGDAFKTGRDMLGKT NPLDSAPGSIRGDFCLDMGRNIIHGSDGVESAQREIEMWFKPEEIVSWEPLIKNMVFESA GKAPVKA---AKDKALKAKKNVQKGNYGIRKRKVRTSVHFRLPKTLKLARKPKYPRRSAP RRPRMDKYKIIKYPLTTESAMKKIEDNNTLVFVVNKKANKPLVKLAVKKLYDIDVAKVNT LIRPDGEKKAYVRLAPDYDALDVANKIGIIMPAKQRMRIANEKASKNVVNRGNVPKTLKD KEDQYPVGPWMLALFVFVVCGSAIFQIIQSIR-XXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXRLYVKAVFTGFKRGLRNQHEGIALLKINGVNSQPDTGFYLGKKCCYVYKA KNKTACPGHKNASKLRVIWGKVVRSHGRSGAVRAKFAKNLPPKAMGRRVRVMMYXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXX-AARPLVSVYNEKGEASGSSITLPACFKAPIRPDIVNDIHFLMKKNSRQAYCV NDKAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRR INVNQRRYALVSAIAASGIPSLVMAKGHRIEEIPEVPFVVSDKMQEIKKTKEAVQFLKKT KAWNDILKVYATKRFSAGKGKMRNRRRTMKRGPLVVYGQDNGICRAFRNIPGVTLINVDK LNVLKIAPGGHVGRFTIWTESAFKKLDSIYGTWRKASTEKTKYNLPMPKMTNTDLGRLLK SERSSRSFAQPS--VSSETLXRDPLKNTRVMTRLNPYAPVQ------------------- -----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXMNIRNAKPQDLMNMQHCNLLCLPENYQMKYYFYHG LSWPQLSYVAEDEGGKVVGYVLAKMEEDPED-VPHGHITSLAVKRSHRRLGLAQKLMDQA SRAMVETFGAKYVSLHVRVSNRAALHLYKTTLKFEINEIEPKYYADGEDAFAMKRDLVSF AEKFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSHRKFSAPRHGSLGFLPRKRSKRHRGKC KAFPKDDKSKPVHLTAFLSYKAGMTHVLREVDRVGSKSHKKEVVEPVTILETPPMVVVGV VGYIDTPRGIRTFKTIFAEHLSDECRRRFYKNWYKAKRKAFTKYSKKWADAQGKIELDKD FGRMKKYCTVIRVLCHSQMKLLKKRQKKAHIMEIQLNGGSIVDKVEWARTHFEKQVNISD IFAQDEMIDVIGVTKGKGFKGVTSRWHTKKLPRKTHKGLRKVACIGSWHPARVGFSVARA GQXGYHHRTENNKKIYRIGKG--AEDGKLVKNNAATEYDMTERXIAPVGGFPHYGE---- ------------------------------------------------------------ ------MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLG LWDTAGQEDYDRLRPLSYPQTDVFLICFSLISPASFENVRAKWFPEVSHHCPNTPIILVG TKLDLREDKETIEKLREKKLAPITYTSGLAMTKEVQAVKYLECSALTQKGLKTVFDEAIR AVLAPKPKTKKKKGCKVL--------------------------------KKKKKKKTPF SMESMSANIPDVEE-EKLKKKKVGSDRDYTYDELLTRVFDIMREKNPDIVAGDRKKLVLR PPQVVRIGSRKTSFVNFHDIAKLLRRQPKHLMAFLLAELGTNGTVDGNNQLIIKGRFQPK HIESVLRRYIKEYVSCHTCKSPDTLLQKDTRLFFLQCNTCGSRCSVTNIKSGFQAVTGKR AAIRYKT-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQVPETLLKKRKENAEKQKAKRQNIFKRAE KYVKEYRIKERDQVRLQREARKHDNFYVPEQPKLAFVMRIRGINGVHPKPRKVLQLFRLR QINNGTFVRLNKATVHMLRIAEPYITWGYPNLKSVRELIYKRGYGKVNKQRVPLSDNAII EKVLGKYGIICIEDLIHEIFTVGPHFKEANTFLWHFKLSTPNGGWRKKSNHFVEGGDFGN RDVRVNPLLRKMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSKAHPPELKKFM DKKLSLKLNGGRVVSGVLRGFDPFMNLVIDEALENRKDGSEAAIGMVVIRGNSVILVEAL ERIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------------- ------------------------------------------------------------ ---------------------------------------DDRGLYAPGQLWLEKKDLVGR ARGFTPYVGMVTILMNDYPKLKYAVLAALGIFVLIHRELXKMNPEYDYLFKXXLIGDSGV GKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYR GAHGIIVVYDVTDQESFSNVKQWLQEIDRYASEQVNKLLVGNKCDLTTKKVVDYTTAKEY ADQLGVPFLETSAKNATNVEQAFMTMAAEIKNRMGPAAAGPTVKINSSTPVKQGGGGCCX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXKPANKVADISQADFGRKEIEIAEKEMPGLMQMREMYGEKKPL KGARIAGCLHMTVQTAVLMETLIALGAEVQWSSCNIFSTQDHAAAAMAKAGIAVYAWKGE TDEEYVWCIEQTLVWPDGKPLNMILDDGGDLTNIVHDKYPQYLENIRGLTEETTTGVHNL YKMMEKGALKIPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGKTALVAGYGDV GKGCCQSLRGFGCRVLVAEIDPINALQAAMEGYEVTTVEEALPKARIFVTATGCADILRP EHMEQMLDDTIVCNIGHFDCEINTAWLNKNA-TRDTIKPQVDRYLMKSGNHIILLAEGRL VNLGCAMGHPSFVMSNSFTNQVLAQLELWTKPGDYKVGVYFLPKTLDEQVARAHLSHLGV KLTVLTTDQAEYLGIKKEGPYKPEHYRYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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APKLISR----------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----RPAAPPGCPSGLEYLTQIDQLLINQQVDVLELFTGWEVANKYTINNSMGQQVYFAG EESDMCQRQCCKEGRGFIFHITDNNKQEVMRISREFKCCAGCCWCANCSWSVDIESPVGT KIGSVVQQYWKPKYEVRDAIFVIDGPCCICQTICCRDDVDFPIMSAQVGTVAKQWAGCCK ETWTRANNFAITFPMDLDVKMKACLLGAVFLIDFMYFEHSDDXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------- ------------------------------------------------------------ ------------------------------------------------------------ -------TISVDDLGRDCIINAAKTSMSSKIIGSQSDFFATMCVDACNLIKVADGKGGFR YPIKAVNVLKAHGQSSSESRLIHGYALNCTVSSQTMTKRVTNAKIACLDFSLQKAKLKMG VQVLVNDAEQLELIRQRESDLTKEKITKILAAGANVVLTTGGIDDLCLKYFVEAGAMAVR RCKKPDLKRIAKATGATFLMTMANLDGEESFEASYLGGAEEVVQEKISDDQLILVKGTKA RTAASIILRGANDFMCDEMERSMHDALCVVKRVMEXXTVVPGGGAVEAALSIYLENFATT LSSXEQLAIAXFAHSXLVIXX--------------------------------------- ------------------------------------------------------------ ---EDSGARLLASKTVFNQYLVEGKDVTVQYAIYNVGSNAAMNVELSDKQYSSEYYEAVR GMHETRWERIAPGSNVTHNVIVRPMQPGYYNFSAATVSYLASEDEPTIAYTTAPGEGAVV SFKDFDRKFSPHVLDWCVFLVMTLPSIAIPAMLWYSSKSKYDTGKGKKSXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------- ----------------------------------------------------------GK PELXKKXMPAVVIRQRKAIRRKDGGFLYFEDNAXVIINNKGEMKGSAITGPVXKEAADLW PKIASHA---RKVREKKVKLGPQVMDGENVFGVAHIFASFNDTFVHVTDLSGKETIVRVT GGMKVKADRDEASPYAAMLAAQDVAERCKVIGITALHIKLRATGGNKTKTPGPGAQSALR ALARAGMKIGRIEDVTPIPSDSTRKKGGRRGRRLMGKPSGLRTARKLRNHRRDQRWADND YKKAHLGTRWKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP NDGCLNFIEENDEVLIAGFGRKGHAVGDIPGVRFKVVKVAGVSLLALFKGKKERPR---V ATIRTRKFMTNRLLCRKQMVVDVLHPGRATVPKTEVKDRLGKMYKTTSDNVFCFGFKTQF GGGTTTGFALVYDSLDAAKKFEPKYRLQRAGTRKQRKERKNRQKKVRGTKKSKVGTMPRI PCVVSKTYKTPRRPFEKERLDQELKLIGEYGLRNKREVWRVKYVLAKMRKTARILLTLDE KDSKRLFEGNALLRRLVRIGVLDEEKMKLDFVLGLKIEDFLERRLQTQVFKLGLAKSIHH ARVLIRQRHIRVRKQVVNIPSYVVRLDSQKHIDFSLKSPFGGGRPGRVKRKNAKKGGGGG GDMGGSFTKLFSSFFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQEAREELNRMLNEDELRD AVLLVFANKQDLPNAMNATEITDKLALHSLRSRSWYIQATCATSGDGLYEGLDWMSNQLK ISK-------LHPSYEDEKRKCKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRRKQHMVRMNVLADCLKSLCNAEKRGKRQVLIRPCSKV IIRFLTVMMKHGYIGEFEVVDDHRAGKIVVNLTGRLNKCGVISPRFDIKIGQIEKWTTNL LPSRQFGFIVMTTSGGIMDHEEARRKHLGGKILGFFFMGRMHAPGKGISQSALPYRRSIA TWLKLSSDDVKEQIFKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILRAKGLAPE IPEDLYHLIKKAVSIRKHLERNRKDKDSKFRLILVESRIHRLARYYKTRTVLPPNWKYES ATASALVAVAEVPEIKLFGKWSTEDVEVSDISLTDYVAVKEKHAKYLPHSSGRYQVKRFR KAQCPIVERLTSSLMMHGRNNGKKLLTMRIVKHAFEIIHLLTGENPLQILVQAIINGGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREAAFRNIKTIAECLADELINAAK GSSNSYAIKKKDELERVAKSNRMGEQLTLRGTLSGHNGWVTQIATTPQYPDMILSSSRDK SLIMWKLTRDGNYGVPQKRLEGHGHFVSDVVISSDGMFALSGSWDSTLRLWDLSTGQTTR QFKGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIEDCHTEWVSSVRFSPNT QNPIIVSCGSDKLVKVWNLTNCKLRTDHFGHTGYLNCCTVSPDGSLCASGGKDGQTMLWD LNEGKHLYTLEGNEIINALTFSPNRYWLCAAAGPTVKIWDLEGKTVVDTLCPDVMGTR-- SRPCASASRASDGQTLFAGYTD-------------XXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTLPMNPKPFL NALTGKPVMVKLKWGMEYKGYLVSVDGYMNLQLADTEEYVDSAFSGNLGEVLIRCNNVLY IRGVDEEAEEGEAHDMSDNEGE-TPAAPAPGAPMDINTALQEVLKTALNHQGLVRGINEC SKALDKRKAHLCVLSQKCEEPSYVKLVEALCAEHGIHLIKVEDNKKLGEWVGQCTPDKDG KARKVVGCSCAVVKDYGKDSPALDVLQEYFKSK-XXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMDDFQSSEETAFVVDEIS NIIKEAVEGAIGGNAYQHNKVNQWTSNVVEQCLNQLTKLGKPFKYIVTCVIMQKNGAGLH TASSCLWDNNTDGSCTVRWENKTMYCIVSVFGLAIMFSGTAKIVKPAGEKPDEFESSISQ ALLDLEMNSDLKAQLRELYINGAKEVEVSGKKAIIIFVPVPQLKAFQKIQTRLVRELEKK FSGKHVVFIAQRRILPKPSRKSKRQNKQQRPRSRTLTSVHESILDDICHPSEIVGKRIRV KLDGSRLIKVHLDKSNQTTVEHKLDTFTGVYKKLTGKDVTFEFPEYVLXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXMKFNKMVTSSRRKNRKRHFQAPSHIRRKLMSSPLSKELKQKYNVRAIPVRKDD EVQVVRGHYKGQQVGKVVQCYRKKFVIHIERIQREKANGASVHVGIHPSKVVITKLKLDK DRKRILETKARSRQHGKHTEESIAPASQTSVGSTLRQRKTGGGNMGSAGMWKFYSEDSPG IKVGPVPVLVMSLLFIAFVFMLHIWGKYQRG------KSTMTEVVTREYTINLHKRIHGI GFKRRAPRALKEIRKFSEKMMGTVDNRIDTQLNKHIWSNGVKSVPFRVRVRLARKRSEDE DSVHKLYTYITHVAVETFKGLSTKNVES-SKSEFIVGAKYRLVRKIGSGSFGDIYLGINI SNGDEVAVKLESTKARHPQLLYESKLYKILQGGVGIPHIKWFGERDYNVLAIDLLGPSLE DLFNFCSRRFTMKTVLMLADQMIGRIEYVHNKNFIHRDIEPDNFLMGIGRHCNKTFLIDF GLAKKYRDSRTRQHIPYREDKNLTGTVRYASINAHLGIEQSRRDDMESLGYVLMYFNRGS LPWQGLKAATKKXKYXXISEK--------------------------------------- ------------------------------MNPEKLKQRIGGKGSARRKKKVVHRTATTD EKKLQNTLKKLSVNNIPGIEEVNMIKSDGSVIHFNNPKVQASLAANTFAVTGNGENKQIT EMLPTILSQLGPENLKSLKKVAAET--IDEGDEDVPELVGNFDEPSKDEMGRYSLDPENA SKAAKARGSHLRVHFKNTRETAQAIKKMHLKRAVKYLKNVTIKKECIPFRRFSGGVGRCA QAKAFGATQGRWPKKSAEFLLQLLKNAESNAEFKGLDTDHLYVEHIQVNAAPKMRRRTYR AHGRINPYMSSPCHIEVILSERDQPIPKGVKKKVSQKKLKKQKMMMREXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXMGISRDKWHKRRKTGGRRPQPRKKRKFELGRPAANTKIGT SRIHTVRTRGGNKKYRALRLDHGNFAWGSEGPTRKTRVIDVVYNASNNELVRTKTLVKGA VIMIDATPFRQWYEEHYATPLARKKNAKLTEEEEARLNARSKKTAKKYEERKKTAAVDRA LEEQFGAGRLMARISSRPGQTGFCDGYILEGRELEFYMKKIKSKKGRMSLVVPEKFQHIL RVMNTNIDGRIKIMYAMTAIKGVGRRFSNLVLKKADVDQRKRAGELTEEEVEAVVTIINN PKQYKIPNWFLNRQKDVKDGKYNQVTSNGLDNKLREDLERLKKIRAHRGLRHYWGLRVRG QHTKTTGRRGRTVGVSKKKSSGDESGS-DDMPELEEVAAAAGLEEELVSKAKQSRGEKKA RKLISKLGLKQIPGISRVTIRKSKNILFVINKPDVYKNPQSDIYIVFGEAKIEDLNQQAQ MEAAEKFRKDEEVDDSGVESKDIELVMSQANVSRPKAVKALKKNNQDIVNAIMMGRVRTK TVKKAARVIIEKYYTRLTLDFHTNKRICEEIAIIPSKRLRNQIAGFVTHLMKRIMKGPVR GISIKLQEEERERRDNYVPEVSALDEVDTDTREMLKFLDFNQIQNLQPIQPIVS-XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMRDLKIQKL CLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVRSFGIRRNEKISVHCTVRGPKAE EILESGLKVKEYELRKGNFSNTGNFGFGIQEHIDLGIKYDPGIGIYGMDFYVVLNRPGMR VTKRRRRVAKLGFNHRVQKDESMKWFQQKYDGIILPGKXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQTERAFQKQPTIFLNKKRLLLQRYTR NVGLGFKTPREAIEGTYIDKKCPFTGDVSIRGRILTGIVTKCKMQRTIVIRRDYLHYVKK YNRFEKRHKNVSVHCSPCFRDVKAGDIVTVGECRPLSKTVRFNVLKINKFSGSSKSFSKF MVNVPKTRRTFCKGKKCKRHTLHKVTQYKKGKDSVVVQGKRRYDRKQSGFGGQTKPIFRK KAKTTKKIVLKMECSECRYKKQLPIKRTKHFELGGGKKVKGQMIQFMGRVIRSQRKGPGS VFRAHTNHRKGAAKLRSVDYAERHGYIKGVVKDIIHDPGRGAPLAKIVFRDPYKYRQNTE TFIASEGMHTGQFIYCGKKASLQVGNILPIGQMPEGTVICSLEEKFGDRGKVARASGNYA TVVAHNPDTKKTRVKMPSGAKRLVPSANRAMVGIVAGGGRIDKPILKAGRAYHKYKVKRN CWPKVRGVAMNPVEHPFGGGNHQHIGMASTVRRDASAGRKVGLIAARRTGRLRGTKTIDA K-----------KYATRYGASLRKMVKRMEVSQHAKYTCQFCGKEAMKRTAVGIWKCKSC KKTVAGGAWVPSTTAAATVRSAVRRLRELKEMGRRPARCYRYCKNKPYPKSRFNRGVPDS KIRIYDLGRKKALADDFPLCVHMVSNEYEQLSSEALEAGRICANKYLVKHCGKDAFHLRI RVHPFHVLRINKMLSCAGADRLQTGMRGAFGKPQGTVARVNIGQTIMSVRSRDAIKDHVI EAFRRAKFKFPGRQKIFLGQNWGFTKWKRENYTSMRQEGILIPDGVGVQYKPNKGPLQAW ----KVLKVLGRTGSQGQCTQVRVEFLDDTSRSIIRNVKGPVREGDILVLLESEREARRL RMTKGTSSFGKRHNKTHTLCRRCGRSSYHIQKKRCASCGYPSQRIRKYGWSVKARRRKTT GTGRMRHMKTVFRRFRNGFREGTVAK----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGAYKYMQELWRKKQSDVMR FLLRVRTWHYRQLTGVHRASRPTRPEKARRMGYRAKQGVCIYRVRIRRGNRKRPVAKGIT YGKPKTHGVNELKPQRSLQSVAEERAGRHCGALRVMNSYWVGEDSTYKYFEIIMVDPFHK AIRRTPDMQWICSNKMKHREMRGLTSAGKKSRGLGKGHTFSKTTGGSRRAAWKKYNTQSM RRKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSIGV PIKVLHEAEGHVITLETTTGEVYRGKLFEAEDNMNCQMTQVTVTYRDGRVSQLENIFIRG SKIRFLILPDMLKNAPMFKQMGVGRGKSAILRAAARGRGRGGRGGGFGRXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXX-------------APKHWMLDKLGGPFAPRPSTGPHKLRECLPLILFIRN RLRYALTYDEAKRIMMQRLIKVDNKVRTDIRYPAGFMDVISIERTNENFRLVYDIKGRFA IHRISPEEAKYKLCKIRKVGVGPKGVPYVTTHDARTIRYPDPLVKSNDTVQIMGSKDDEY DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSINVDGKTIKAQIWDTA GQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDL RHLRAVPTDEAKAFAEKNALSFIETSALDSTNVETAFVNILTEIYKIVSQKPMGRDGDD- ----------------------MSERYSFSLXXFSPSGKLVQIEYALNAVSAGAPSVGIK ASNGVVLATEKKQKSILYDEHSVNKIECISKNIGMVYSGMGPDYRVLVKAGRKISQQYQL AYQDHIPSSQLVSRVAAVMQEYTQSGGVRPFGVSLLVAGWDKRPYLYQCDPSGAYFAWKA TALGKNHINAKTFLEKRYSDTLE--EDAVHTAILTLKESFQMTENNIEIGICNQD-GFRR LSPAEVKDYL-----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXMGDRYNIHSQLEHLQSKYVGTGHSDTTKWEWL TNQHRDSYASYMGHFDMMNYFSIAENESRARVRFNLVERMLQPCGPPPERPEDMKIEVCY YSGLKIYPGHGKRFIRVDGKVHHFLSAKCAASHFMKRNPREIPWTILYRRKNKKGQTEEE KKKRTRRTHKFVRAIAGSTLQDLQAKRNQKPEIRKAQREQAIRAAKEKKRTEKSAAPKVG GKRMKLNISFPATGCQKLIEVDDEKKVRIFYDKRISAEVDVSSLGDEWKGYVFRITGGND KQGFPMKQGVLTATRVKLLLSKGHSCYRPRRKGERKRKSVKGCIVDNTLSVINLVIVKKG EGEIEGLTNETKPRRLGPKRASNIRKLFNLTKDDDVRQYVVRRPLQATTRAPKIQRLITP LTLQRKRRRVALKRRRAEKQREDASEYAKLLAKRMKEAKDRKAERKRSASHSRKVKAKDL RGKKREDLEKQLEELKQELSTLRVAKVTGGAASKVSKIRVIRKSVARVMTVCHQKQKENL RKVYKPKDLRPKLTRNLRRQLTPHERRMKTAKQQRRERLYPMRKFAVKXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKKKKIHHEFTLD CTHPVEDGILDVAQFEKFLVERIKVGGKTGNLKSKITVHADIPFSKRYLKYLTKKFLKKH SLRDFLRVVAHTKDSYELRYFNVNNEDDDDDGDD--SQQGDEEKKFGGCEGPDAQYVKLI SSDNHEFIVRRDHALTSGTIKAMLSGPGQFAENETNEINFREIPSHVLQKVCQYFTYKVR YTNSSTEIPEFPIAPEIALELLMAANFLDCXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPKEKIHVNIVVI GHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITI DIALWKFETTKFMVTIIDAPGHRDFIKNMITGTSQADCAVLIVASGTGEFEAGISKNGQT REHALLAFTLGVKQLIVAVNKIDSTEPPYSETRFKEIEKEVSAYVKKVGYNPKAVAILPI SGWHGDNMINMTWWKGWKVAAGNTLFEALDNVLPPERPTKLALRLPLQDVYKIGGIGXVP VGRVETGILKPGTIVTFAPVGLTTEVKSVEMHHEQLTEANPGDTL--------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMSKINKDNLNDSIATILTKKRKFTETIELQVSLKNYDPQKDKRFNGTVKLRYVPRPK LRVCVLGDQAHCDEANANNVDCMDVDALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPR LLGPGLSKAGKFPGILTHNDSLVAKIADIKATIKFQMKKVLCLSVAVGNVDMQQDELYHN IALSVNFLVSLLKKNWQNVRAVYVKSTMGPSQRIYXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXX---SEIQNLQDPFAEDGVIHIRIQQRNGRKTLTTVQGIDTKYDLKRI IKACKKEFACNGTVVEHPEYGEVIQFQGDQRENIGSWLVRVGIAELIKTHGFXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX----STVIARTVQRTLPKRHAPGAAFVAAHKFSTSAEVSSILEDRILGATKADLEET GRVLSIGDGIARVYGLKNIQAEEMVEFSSGLKGMALNLEPDNVGVVVFGNDKLIKEGDIV KRTGAIVDVPVGEGLLGRIVDALGNPIDGKGPIDSNQRQRVGIKAPGIIPRTSVKEPMQT GIEAVDSLVPIGRGQRELIIGDRQTGKTAVAVDTIINQKRFNDAAEEKKKLYCIYVAVGQ KRSTVAQLVRRLTATDSMKYTIIVSATASDAAPLQYLAPYSGCAMGEFFRDNGKH----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --ALLKLPFSVLECPNLKIKKPSWIRMPSAMFMFGLVLLSYFLVTGGIIYDVIIEPPSIG STTDERGHSKPVAFMPYRVNGQYIMEGLASSFLFTLGGLGFILLDQTNKPLMPRLQRILL MSVGFSCILVSFFACRVFMRMKLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEYAQVLKMLGNG RLEARCFDGVKRLCHIRGKLRKKVWINAQDIILIGLREYQDNKADVIMKYTADEARNLKT YGELPETVNITDADDVEIGYDGSDD-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPILIDGRGHLLG RLASIIAKTLLQGQRVVVVRCEQINISGSLYRNKLKYQDFLRKRMNTNPKKGPYHFRAPS KILWRVIRGMLPHKLTRGKEAMERLKTFEGIPSPYDKKKRLVIPAALKSMRLHPRRKFCT VDRMSHEVGWKYKGVIETLENRRKNRSALYHKKRTGINRLREQAIKIAPYQKIIEGYG-- GNPEKGRKVFVQKCAQCHTVEAGGKHKTGPNLNGLIGRKTGQAAGFSYTDNNKNKGITWA ADTLFIYLENPKKYIPGTKMVFAGIKKKGERSDLITFLHKGT-XXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX MTNTKGVRRGTRYMFSRPYKKGGVIPLSTYMKIYKRGDIVDIKGHGAVQKGMPHKVYHGK TGRIFNVTPHAVGVIVNKRVGGRIIPKRINLRVEHVKHSTCRLDFLRRVKDNEKKLGEAK ATVSCKRIPTQPRKGHFVKTRYCKPQVIEPIPYEFIAXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXKKLTKEEEVLLQDFSRNVTTKSSALFYGNAFIVSAIPIWLFWR IHQMDPSIFFILGVAVSTYFMAFAYKNVKFVLKHKVAQKREKAVTEEVMKTIADDKKMSR KEKDERVLWKKNEVADYEATTFSIFYNNALFLFLIVVLSFWVFRSFSPTVNYVVSMGSVS GLIALLSTGSQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXMAEYLASIFGTEKDRVNCPFYFKIGACRHGDKCSRQHNKPTFSPTIMMAN LYINPGNLALVMTNEADAQEHFEDFFEEVYLECNDKYGEVEEMHVCDNLGDHLVGNTFIK FRSEEDAEKAVVELNNRWFNGRPIVCELSPVTDFRESCCRQYEMGECTRGGFCNFMHLKP ISRDLRRKLFRGRGRSRSXSPRRKPRRSRS----RDRHRDREERRXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXEDGGARLLASKTVFNQYLVEGKDITVQYAIYNVGSSAAMNVELSDKQYSAEYYEAVR SARDAXWERVAPGSNVTHNVIVRPMQAGYYNFSAATVSYLATEDDPTVVYTTAPGEGGVV SFKDFDRKFSPHVLDWFVFLVMTLPSIAIPAMLWYSSKSKYDTGKGKKSXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX >Perionyx_excavatus XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMDQVM TYVEPARQFVKDSIRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNII VMAAPISKKRKFVADGVFKAELNEFFTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVL GEKGRRIRELTAVVQKRFNFPEGTVELYAEKVATRGLCATAQAESLRYKLTGGLAVRRAC YGVLRFIMESGAKGCEIIVSGKLRGQRAKSMKFLDGLMIHSGDPMNDYVDQAVRHVLLRQ GVLGIKIKIMLPWDPSGKTGPKRPLPDHVSILDPKDQSTPEQPWSEQKGAKMSKRGRGGS SGGKFRISLALPVGAVINCADNTGAKNLYIISVHGIRGRLNRLPAAGCGDMVMATVKKGK PDLRKKVMPAVVIRQRKTIRRKDGLFIYFEDNAGVIVNNKGEMKGSAITGPVAKECADLW PRIASNAGCIRKQKTVKVTLGPQVAEGENVFGVAHIFASFNDTFVHVTDLSGKETLVRVT GGMKVKADRDESSPYAAMLAAQDVAERCKQLGITALHIKVRATGGNRTKTPGPGAQSALR ALXRAGMKIGRIEDVTPIPSDSTRRKGGPRGRRLXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--- ATIRTRKFLTNRLLCRRQMVVDVLHPGRATVPKTEIREKLARLYKTTADVVFCFGFRTQF GGGKTTGFALIYDTLDFAKKFEPKYRLTRHGARKQRKERKNRQKKVRGTKKAKVGAMPRI GLVRSKTYSTPRRPFEKERLDQESKLIGEFGLRNKREVWRVKYTLTKIRTAARELLTLDE KDPRRLFEGNALLRRLVRIGVLEESKMKLDYVLGLRLEDFLERRLQTQVLKLGLAKSIHH ARVLIRQRHIRVRKQVVNLPSFIVRLDSQKHIDFALNSPYGGGRAGRVKRKNQRKQAGGG EA---------------------------------------------------------- ---------------------------QGLIFVVDSNDRERVGEAREELMRMLAEDELRD AVLLVFANKQDLPNAMNAAEITDKLGLHSLRQRNWYIQATCATSGDGLYEGLDWLSNQLK NQKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXMVRMNALADALKSICNAEKRGKRQVLIRPRSKV IEKFLLVMMKHGYIGDFEIIDDHRAGKIVVNLTGRINKCGVISPRYDVSVKSIESWTTAL LPSRQFGYIVMTTSGGIMDHEEARRKHLGGKILGFFFMGRMHAPGKGISQSALPYRRSVP TWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQTRYVSGNKILRILKAKGLAPT IPEDLYYLIKKAVAIRKHLERNRKDKDSKFRLILVESRIHRLARYYKTRKVLPPVWKYES STASALVA---------------------------------------------------- -------ERLTDSLMMHGRNNGKKQMAMRIVRHSFEIIHLLTGENPLQILVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREASFRNIKSIAECLADELINASK GSSNSYAIKKKDELERVAKSNRMSEQMTLRGTLQGHGDWVTQIATTPQYPDMILSASRDK KLILWRLTRDVRYGYPQKALHGHSHFVSDVVLSSDGQFALSGSWDHTLRLWDLSTGQTTR RFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTIDDCHTDWTSCVRFSPNT QNPIIVSCGWDRLVKVWNLTNCKLKTNHYGHTGFLNTVTVSPDGSLCASGGSXSQAMLWD LNEG-------------------------------------------------------- -----------------------------------XXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX--------------------------------------------- -----KRQAHLCVLANNCDEQNYVRLIEALCAEHGINLIKVESNKKLGEWVGLCKLDKEG KARKVVGCSCVVVKDYGKESQALDVLNEYFKTRK--SIRKKLVVVGDGECGKTCLLSVFC KDEFPEIHIPTVFETDITDIEXDGKLVELSLWDTAGQEDYDRLRPLSYPDTDIVLICFSI SNPVSLSNISEKWFPEVKHFCPNIPILLIGTKKDLRTNEDSTEKQKQSKLKTVPFETRLQ LSQTMKAYAFLECSAKTKEGVRDVFSMAARASLANKTK----XXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGRGGFRGGFGGR GRGRGRGRGGGKEGDKEWVPVTKLGRLVKDQKIKTIEEIYLFSLPIKEAEIIDYFLGTTL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDFNGHVGLGVKCSKEVATAIRGAITLAKLSI VPVRRGYWGNKIGKPHTVPCKVTGRCGSVLVRLIPAPRGTGIVSAPVPKKLLHMAGIDDC YTSASGQTATLGNFAMATYHAIANTYCYLTPDLWKETVFVKSPYQEHTDYLMKMSGSLDV LALREDDVAKFLSCQTHVGVSSLDFQMEQYVFKRRTDAIHIINLRKTWEKLLLAARAIAA IENPADICVISARPYGQRAVLKFAHYTGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDP RTDHQPVREAAYVNIPVIALCNTDSPLRHIDIAIPCNNKSVHSIGLMWWLLAREVLRLRG TISREMPWEVMVDLFFYRDPEETEKEAEVVDWAAESTAAPAPVATEDWSATDTGDWGATP ASNEWGGMKFNKFVTSSSRKNRQRHFNAPSHIRRKIMSSPLSKELRQKYNVRSIPIRKDD EVQVVRGHHKGQQVGKVVQVYRKKYVIHIERXQREKVNGTTSYVGIHPSKVVIVKLKMDK DRKSILERKAASRQKGKHSEESVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKRESKKKSVTNEVVTREYTINLHRRIHGI GFKKRAPRAIKEIRKFAEKQMGTPDVRIDTRLNKFMWSQGIRNVPFRVRVRLARKRNEDD DSPNKLYTLVTYVPVTTFKGTQTVNVESXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNAEKLKQRIGGKGTARRKKKVIPKNTAAD DKKIQLAVKKIGVSVINGIEEVNLFKDNGEVICFNNPKVQACLQSNTFVVTGHAETKQIT DMLPSLLSQLRGESLASLGSLSS--VEID-EDDEVPDLVENFDEPSKTEXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXMGISRDKWHKRRKTGGRMAQVRKKRKFELGRPAASTKIGA RRIHTIRTRGGNKKYRAMRLDTGNFSWGSEGVSRKTRVLDVVYNASNNELVRTKTLVKNA VVVIDAVPFRNWYEAHYSLPLSRKKGAKLTTEEEARLNKRSKKAQRKYDTRKKTAKVEPS LEEQFASGRLLACVSSRPGQCGRCDGYILEGKELEFYNRKIKAKKGKMSLVLPEKFQHIL RVMNTNIEGKRKVPFALTAIKGVGRRYAHVVCKKANVDFTKRAGELSDEEVEKLITIMSN PRQYKIPDWFLNRQKDVKDGKYSQVMSNTLDSKIREDLERLKKIRTHRGLRHFWGLRVRG QHTKTTGRRGRTVGVSKKKDSATESDGEESVPELEDVAEAAGLPDELVSKAKQSRSEKKA RKAMSKLGLKQIPGVSRVTVRKSKSILFVINRPEVFKSPVSDTYIMFGEAKIEDLSQQAQ MAAAEKFKADEEVDETGIEAKDVELVMSQAGVTRSKAVRALKNNQNDIVNAIMXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMRNLRIQKL SLNICVGESGDKLTRAAKVIEQLTGQSPVYSKARFTVRSFGIRRNEKIAVHCTVRGAKAE EILDKGLKVREYELKQGNFSNTGNFGFGIQEHIDLGIKYDPNIGIYGMDFYVVLGRAGFS ISKRRRAQGSIGNKHRVTKGEAMKWFQQKYDGVILPGKXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------------- ---LGFKTPREAKEGHYIDKKCPFTGNISIRGRILTGVVAKMKMQRTIVIRRDYLHYVPK YERFEKRHKNLSVHLSPCFRDVQVGDIVTVGECRPLSKTVRFNVIKVAKGTGSKKGFSK- XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXKVTKILGRTGSQGQCTQVRVEFLDESSRSIIRNVKGPVREGDILTLLESEREARRL R---GTSSFGKRHNKTHTLCRRCGGRCYHIQKKSCARCGYPEKRIRKYNWSEKAKRRRTQ GVGRMRHLKVVFRRFRNGFREGTVAKKVIQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----FIQEISRKKQSDSMN FLSRTRCWLYRQLPSVHRAPRPTRPDRARRLGYKAKQGFIIYRVRIRRGGRKKPVPKGQV YGKPKSCGVNQLKNQRSLQAVAEERVGRRCGALRVLNSYWIGEDSTYKYYEVVLVDPFHK AIRHDPQIQWICKSVAKHREMRGLTSANRKSRGLGKGHGYSKTIGGSRHACWKRNNTIQM RRKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXLGFAENFALSGAAAIISKTAAAPIERVKLLVQNQGEMLKSGRLDKPYSGVIDCTV RTFRNEGIIPFWRGNLANCIRYFPTQALNFAFKDKIKAAFVMNKTDSYTVKFSKNIASGG VAGALSLVFVYSLDYCRTRLANDAKAGKKRQFNGMIDVYVKTVKSDGFVGLYRGFV---- ------------------------------------------------------------ ---------------------------------------------------------XXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------- ---SINSRLALVMKSGKYVLGYQQTLKSLRQGKAKLVIIANNTPPLRKSEIEYYAMLAKT GVHHYNGNNLELGTACGKLFRVTTLSITDPGDSDIIRSMP--XXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMRVDLCV FSGLKIYPGHGKKLVKVDGKTFHFVNAKCAKLHLAKRNPRKVNWTVLYRRKHKKGLTEEI AKKRTRRTAKFQRAITGASLTDIMAKRNQKPEVRQAQREQAIRAAKEKQKAKAKAQPRVG GKRMKLNISYPATGCQKLIEVDDERKLRAFYDKRMATEVSAESLGDEWKGYVVRISGGND KQGFPMKQGVMTNGRVRLLLSDGHSCYRVRRDGERRRKSVRGCIVDANLSVLNLVILKKG EQEIPGLTDSTVPRRLGPKRASKIRKLFNLSKKDDVRQYVVRRPLAPQTKAPKIQRLVTP VVL--------------------------------------------------XXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------THEV TFRMYIGGQFAGDIVFAIFYNICPKTVENFLAFVNGNAPYKGNIWHRVIKGFMGQGGDVI SQNGWGVVSIYFPDENFAIHHNGAGWLGMANAGKDTNACQ-------------------- ------------------------------------------------KKKKTSQKFTLD CAHPVEDGIMDVMSIEKFLIERIKVNGKIGNLKSKIIVSAEIPFSKRYLKYLTKKYLKKN NLRDWLRVVANGKDSYELRYFQINNEEEDEIEDKXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------LPHEILEMTSKFMTEPI RILVKRDELTLEGLKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKM REANFTVSSMHGDMPQKERDAIMKEFRAGTSRVLISTDVWARGIDVQQVSLVINYDLPNN RELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLIXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXMSTTLQPYLKAVRQTLTAAICVENFSSQVVERHNKPEVEVRTS KELLLTPVTISRNEKEKVLIEGSINSLRISIAIKQADEIEKILCHKFMRFMMMRAENFII LRRKPVEGYDISFLVTNFHTEQMYKHKLVDFIIHFMEEIDKEISEMKLAVNSRARISAEE FLKRFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGAEKTHINIVVI GHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITI DISLWKFETAKYYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQT REHALLAFTLGVKQLIVGVNKMDSTEPPYSEARFEEIKKEVSTYIKKIGYNPEAVPFVPI SGWHGDNMLKMSWF---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPRQ LLEIKDFLMTARRTDAKSVKIKKNTKFKLRCSRYLYTLFINDGEKAEKLRQSLPPGLQVK ELKMSKISREMLMEAINSVLQKKRKFTETVELQISLKNYDTQKDKRFSGTVRLRHVPRPK MTVCVLGDQQHCDEAKANSVPCMDQDALKKLNKQKKPIKKLAKQYDAFLASDSLIKQXPR IVGPGLNKS--------------------------------------------------- -----------------------------------XXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- -----------------------------------VLINCRNNKKLLGRVKAFDRHCNMV LENVKEMWTEVPKTGKGKKKSKPVNKDRFITKMFLRGDSVILVLRNPL------------ ---------------------------GNFYRNKLKYLDFLRKRMNTNPSRGPYHFRAPS KIFWRTVRGMLPHKLHRGKEALENLKAFEGIPPPYDKVKRQVVPSAMRVLRLKPRRKYCK LGRLAHEVGWKYPTVVGTLERRRKLKATVYYKSKVKEEKLKKLARKNPQLQKII-----A GDPEKGKKVFVQRCFQCHTVEKDGKHKQGPNLHGLIGRATG------------------- -------------------------------------------XXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXX-------------------------------------------- ------------------------------------------------------------ -----------------------------------------------KGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIMSGVIDLKGDKSKVSLVYG 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXEHIIVETKGEKSNVGFIALNRPKALNALCDGLMKEL GAALVEFDKDPNIGCVVLTGAEKAFAAGADIKEMESLTFQDVCSKNFLDSWTFVADFKKP IIAAVNGFALGGGCELAMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTQAVGKSKAM EMVLTG------------------------------------------------------ ---------------------------------------- >Phascolosoma_granulatum -TDRKAVIKNADMTEEMQQDAVDCATQALEKYNIEKDIAAFIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSG--TQFRQFQTSAVQRDIDQAAKYIGAGAATV GVAGSGAGIGSLFGSFVIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLILFAFM SHYKETGKAPGTPIHRIRITLTSRNVKSLEKVCSDLIQGAKEKNLKVKGPVRMPTKILRI TTRKTPCGEGSKTWDRYQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADMDQVM QFIEPAKTFSKDSIRLVKRCTKPDRKEFQKVAIATAIGFAIMGFIGFFVKLIHIPINNII VMATPVSKKKKFVADGLFKAELNEFFTRELAEDGYSGVEVRVTPTRTEIIILATRTQQVL GDKGRRIRELTSVVQKRFNFPEGTVELYVEKVANRGLCAITQCESLRYKLIGGLAVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGEPCADYVDMAIRHVLLRQ GVLGIKVKIMLPWDPSGKMGPKRPLPDHVSIVEPKEEVLPAQPISEQKGGK--------- -------------------------KNLYVIAVNGIKGRLNRMPAAGVGDMVVATVKKGK PDLRKKVMPAVIIRQRKNIRRKDGVFLYFEDNAGVIVNNKGEMKGSAITGPVCKECADLW PRIASNASSI-------VSLGPQVVEGENVFGVAHIFASFNDTFVHVTDLSGKETLVRVT GGMKVKADRDEASPYAAMLAAQDVSERCKALGITALHIKLRATGGNKTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRLMGKPRGLRTARKLQSHRRDQKWHDKD YKKSHLGTRWKANPFAGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP RDGCLNFVEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLWALYKEKKERPRS--- ATIRTRKFMTNRLLSRRQMIVDVLHPGRATVPKTEVREKLARMYKTTPDVVFAFGFHT-- ------------NXXXXXKKFEPKYRLARHGARKQRKERKNRQKKVRGTAKAKVGAMPRI PLVCSKTYTTPRRPFEKERLDQELKLIGEYGLRNKREVWRVRYTLAKIRKAARELLTLDE KDQKRLFEGNALLRRLVRIGVLSEDKMKLDYVLGLRLEDFLERRLQTQVFKLGLAKSIHH ARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFALKSPYGGGRPGRVKRKNMKKGKGGD AAMGNIFQSLFKGLFGKXEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVGEAREELMRMLAEDELRD AVLLVFANKQDLPNAMNAAEITDKLGLHSLRNRNWYIQATCATSGDGLYEGLDWLSNQLK NMKMPLAKDLLHPSLDEEKRKCKLKRLVQSPNSYFMDVKCPGCYRITTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRRKQHMVRMNVLADALMSIGNAEKRGKRQVLIRPSSKV IVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDIKLRDMEKWTTNL LPSRQFGFLVLTTSGGIMDHEEARRKHLGGKILGFFFMGRMHAPGKGISQSSLPYRRTVP TWLKVTSEDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVAGNKILRILKAKGLAPD IPEDLYQLIKKAVSMRKHLERNRKDRDSKFRLILVESRIHRLARYYKTRKVLPPNWKYES STASTMVAVAELPEVKLFARWSADEVQVSDISLTDYIAIKEKYAKYLPHSAGRYQVKRFR KAQCPIVERLTSSLMMHGRNNGKKLLAMRIVKHAFEIIHLLTGENPLQVLVNAVINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREAAFRNIKTIAECLADELINAAK GSSNSYAIKKKDELERVAKSNR--EQMTLRGTLQGHGGWVTQIATTPQYPDMILSASRDK TLIMWKLTRDQNYGIPQKALRGHGHFVSDVVMSSDGQFALSGSWDHTLRLWDLGTGQTTR RFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIEDGHSEWTSCVRFSANT QNPVIVSCGWDRYVKVWNLSNCKLKTNHIGHTGYLNCVTVSPDGSLCASGGKDGQAMLWD LNDGKHLYTLEGGDEINALCFSPNRYWLCAATGPSIKIWDLEGKLVVDELRPEVINTSAE PPQCISIAWSSDGQTLFAGYTDNLIRVWQVSLAARMREYKLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKVVEVDGNQCMLEILDTAGTEQFTAMRDLYMKDGQG-------- ------------------------------------------------------------ ---------------------MSEEKKDSSEHINLKVTGQDGSVVHFKIKKNTPLRKLMT AYCDRTGFKMDSMRFRFDGQPINESDTPSQLEMEDGDSIDVFQQQT-----LPMNPKPFL NGLTGKPVMVKLKWGMEYKGYLVSVDGYMNLQLANTEEYIDGTLSGNLGEVLIRCNNVLY IRGVEEEDE------MSEAEGDDVPS--VATGPMDINTAIQEVLKTALVHDGLARGLHEC AKALDKRQAHLCVLANNCDEPMYVKLVEALCAEHGINLLKVDDNKKLGEWAGLCKIDRGG QARKVVGCSCVVVKDYGKETQAHDVLMEYFKSKK-------------------------- -------------------------------------EDYDRLRPLSYPDTDVILMCFSI DSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDENTKRELMKMKQEPVRPEEGRA MHDQIRAYAYLECSAKTKEGVREVFETATRAALQTKKKKKSKXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMYSASAKIVKPQGEKPDEFESSISQ ALLDLEMNSDLKAQLRELYITAAKEIDVAGKKAIIIFVPVPQLRAYQKIHVRLVRELEKK FSGKHVVFIAQRRILPKPTRKSRAKNKQKRPRSRTLTAVHDAILEDLCFPAEIVGKRIRI KLDGSRLIKAHLDKSQQTNIEHKVDTFSAVYKKLTGKDVTFEFPEYVLGRGGFRGGFGGR GRGRGRGRGRGKD-EKEWIPVTKLGRLVKDMKIRTLEEIYLFSLPIKEFEIIDYFLGSAL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDYNGHIGLGVKCSKEVATAIRGAIVLAKLSV IPVRRGYWGNKIGKPHTVPCKVTGKCGSVVVRLIPAPRGTGIVSAPVPKKLLHMAGIDDC YTSARGQTATLGNFAKATYAAIANTYSYLTPDLWKENQFTKAPYQEFTDYLAKMSGGLEV LSLKEDDVTKLLASGAHLGSQNCDFQMEQYVFKRKNDGIHIIDLRKTWEKLLLAARAIAA IENPADVCVISARPYGQRAVLKFASATGATPIAGRFTPGTFTNQIQAAFREPRLLMVTDP RTDHQPVTEASYVNIPVIALCNTDSPLRYVDIAIPANNKGEHSIGLMWWFLAREVLRLRG TISREVPWDVMVDLYFYRDPEEAEKEQAVTDWASESVPPPAPMVTDDWAA-ETHDWSAPA A------MKFNKLVTSSRRKNRLRHFNAPSHVRRKIMSSPLSKELRTKYNVRSIPIRKDD EVQVVRGHYKGQQVGKVVQVYRKKFVVHIERIQREKANGATVHVGIHPSKVVIMKIKMDN NRKRILERKAKSRTQGKH-----APASSTSVGSTVRQRKTTSSGAGAAGMWRFYTEDSPG IKVGPVPVLVMSLLFIASVFMLHIWGKYTR-TEKGKKKSTINEVVTREYTVNIHKRIHGI GFKRRAPRAIKAIRKFAEKMMGTPDVRVDTRLNKHMWSKGVRNVPYRVRVRLARKRNEDE DSANKLYTLVTYVPVTTFKGTQTVNVDSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNPEKLKRRIGGKGTARRKKKVVHRTAATD DKKLQSSLKKLGVNVIPGIEEVNMIKDDGQVIHFTNPKVQASLTANTFAITGHAETKQIT EMLPGILSQLGAESLANLKKMTTDTGDVDDEEEDVPELVGNFDEASKDEMTRYSLDPENS AKSVKARGSHLRVHFKNTRETAQAVKKMHLRRAVRFLKNVMTQAECVPFRRYCKGVGRHA QAKNWKASLGRWPKKSAEFLLQLLKNAESNAEYKGLDTDHLVIEHIQVNKAPKMRRRTYR AHGRINPYMSSPCHIEVILAEREQAIAKASKKKVSQKKLKRQKMMMREXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXMGISRDKWHKRRKTGGRKNPLRKKRKFELGRPPANTKIGA RRIHTVRTRGGNKKYRALRLDAGNFSWGSEATSRKTRIVDVLYNASNNELVRTKTLVKNA IVQIDATPFRQWYEAHYALPLGRKKNAKLSEAEEAVLNKRSKKTQKKYEKRRKVAKVETA LEEQFQTGRVVACLSSRPGQCGRADGYILEGKELEFYLRKIKAKKGK-TLVIPEKFQHIL RVMNTNIDGKRKIPFALTAIKGIGRRYAHIVCKKADVDVTKRAGELTEDEVEKLMTVVQN PRQYKIPNWFLNRQKDVKDGKYSQVMSNMLDNKLREDFERLKKIRAHRGLRHYWGLRVRG QHTKTTGRRGRTVGVSKKKDEGSETDSDDEVPDLEDVAQAAGINEDMTSKQKQSRSEKKA RRAISKLGLKNVAGVSRVTIRKSKNILFVINRPDVYKSPASDTYIVFGEAKIEDLSQQAQ MQAAEKFKADEPVDETGVEQKDIELVMSQANVSKNKAIKALKDNNNDIVNAIMMGRVRTK TVKKASRVIIEKYYTRLTLDFHTNKRICEEIAIIPSKKLRNKIAGFVTHLMKRIQRGPVR GISIKLQEEERERRDNYVPEVSAIEEVDPDTKEMLKAMDMGNIPNLQVT----------- -------------EKIRKKYPDRVPVIVEKAPKARVGDLDKKKYLVPSDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGALYQEHHE----------------MRDLRVRKL CLNICVGESGDRLTRAAKVLEQLTGQQPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAE EILERGLKVREYELKKNNFSATGNFGFGIQEHIDLGIKYDPGIGIYGMDFYIVLGRPGFN VAYRRRKNSRIGFKHRVTKDEAQKWFQQKYDGIILPGKMGIKFLEFVKPFCAVLPEVAKP ERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWIRVILASNRGTLMELGIS PIVTSSLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMVITVGQAIVYVMTGMYGEPAE IGAGVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVN TGRGTEFEGAVIALFHLLATRQDKVRGLREAFYRQNLPNLMNLMATILVFAIVIYFQGFR VDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAAKFSGNFFVNLLG VWADVGGGGAARSYPVGGLCYYFSPPETLSHVGEDPVHAVLYIIFMLGSCAFFSKTWIEV SGSSAKDVAKQLKEQQMVMRGHRDKSMIHELNRYIPTAAAFGGLCIGALSVMADFMGAIG SGTGILLAVTIIYQYFEIFVKEQSEMGGMSTLL-QTERAFQKQPTVFLNKKKALVLRYFK NIGLGFKTPREAIDGNYIDKKCPFTGNVSIRGRILTGVVLKCKMQRTIVIRRDYLHYVRK YNRFEKRHRNMSVHCSPAFRDVAIGDVVTIGECRPLSKTVSFNVLKVNKASGTKKGFSKF MVNVPKARRTFCKGAKCRKHTLHKVTQYKKGRDSLYAQGKRRYDRKQSGYGGQTKPIFHK KAKTTKKITLKMECTECKSRKQLSIKRCKHFELGGDKKKKGQMIQFMGRVIRSQRKGPGS VFKAHTKHRKGAAKLRALDFAERHGYIKGVIRDIIHDPGRGAPLAKVAFRDPYRYRSKTE TFIAAEGMYTGQFVYCGKKATLQVGNILPVGVMPEGTIICCMEEKTGDRGRVARASGNYA TVIAHNPDTKKTRVKLPSGTKKTVPSANRAVVGIVAGGGRIDKPLLKAGRAYFKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGKASTVRRDTSAGRKVGLIAARRTGRLRGSKQLTG KAKRTKKVGIVGKYGTRYGASLRKTIKKMEVSQHGKYTCSFCGKDAMKRKAVGIWSCRRC GKTVAGGAYVYSTSAAATVRSAVRRLREVKEMGRRPARCYRYCKNKPYPKSRFCRGVPDS KIRIYDLGRKKARVDDFPQCVHLVSDEYEQLSSEALEAARICANKYLVKMCGKDAFHLRI RVHPFHICRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQPIMSVRGRDQHKNAMI EALRRAKFKYPGRQKIYVSSKWGFTKWEREDYVKMRADGRLVPDGVNVQYKPNHGPLQAW RDAQKVTKVLGRTGSQGQCTQVRVEFLDDSNRSIIRNVKGPVREGDILTLLESEREARRL RMTKGTSSFGKRHNKTHTLCRRCGRRAYHIQKKACARCAYPLARQRHYNWSVKAKRRRTT GTGRMAHLKKVQRKFRNGWQEGSVPKPRQRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGAYKYIQELYRKKQSDVMR FLLRVRSWHYRQLSSIHRASRPTRPDKARRLGYRAKQGFVIYRVRVRRGGRKRPVPKGAT YGKPTNQGVNQLKNERSHQNIAEERVGRFCKSLRVLNSYWVAQDSTYKFFEIILVDPFHK AVRRDPNYQWLCKPVMKHREMRGLTSAGKKSRGLGKGHKFHKTIGGSRRASWKRRNTMQA RRKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXX-------------------------------------------------------- ------------------------------------------------------------ -------------------------------SNYNFEKPFLWLARKLIGDPNLEFVTMPA LAPPEVEMDPKIAAQYELDLKEAQSTALPDDDDDLXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXLSFAESFALSGAAAVISKTAAAPIERVKLLVQNQDEMIKAGRLSEPYKGVIDCTT RTFKTEGILPFWRGNLANCIRYFPTQALNFAFKDQIKRAFKMHPTDSYGVKFSKNVASGG AAGAMSLCFVYSLDYARTRLANDAKGASKRQFNGLIDVYKKTLKSDGFVGLYRGFVISCV GIVVYRGCYFGFYDTLKPIVLGDDANLVLAFMLGYVVTISAGLVSYPIDTIRRRMMMTSG QAVKYKGSIDCFLQIMRTEGFMSLMKGAGANILRGVAGAGVLAGFDEFKKYYIKLR-XXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSIGV PIKVLHEAEGHVVTCETNTGEVYRGKLIEAEDNMNCQMSNITVTYRDGRVAQLENVFIRG SKIRFLILPDMLKNAPMFKRIGAGRGKSAILRAAARGRGRGGPRGGG--MQNEGGEFVDM YIPRKCSASNRIISSKDHASIQLNIADVDPTTGRMTGQYKTYAICGNIRRMGESDDSLSR LAKKDGIVSKMGRGPKKHLKRLNAPSHWMLDKLSGVFAPKPSAGPHKTRECLPLMVFLRN RLKYALTYDECKRILNQRLIKVDGKVRTDNTYPAGYMDVVTIDKTGEHFRLVYDVKGRFA VHRITAEEAKYKLCKVKKVAVGPKKVPYCVTHDGRTIRYPDPNVKANDSVQVXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------------------- ------------------------MERIKDYLLMEEEFIRNQERLKPQEEKHEEERSKVD DLRGTPMSVGNLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDQLEPGCSVLLNHKVHAVV GVLGDDTDPMVTVMKLEKAPQETYADIGGLDAQIQEIKESVELPLTHPEYYEEMGIKPPK GVILFGPPGTGKTLLAKAVANQTSAT---------------------------AEEHAPS IVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSKGDVKVVMATNRIETLDPA LIRPGRIDRKIEFPLPDEKTKRRIFNIHTNRMTLAADVNIDDYVMAKDDLSG-------- ---------------------------------------------------NTVDFALAR VDDLVNWARKSSLWPMTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQADCMIVAGTL TNKMA------------------------------------------------------- ---------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMVGQKKTKK AAESINSRLQLVMKSGKYVLGYKQTLKTLRHGKGKLVIIANNTPPLRKSEIEYYAMLAKT GVHHYNGNNIELGTACGKYFRVTTLSITDPGDSDIIRSMPS-XXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKLELCA YSGYKIYPGHGRRLIKTDGRTFIFLSAKCEASHLMKRNPRKISWTVLYRRKNKKGQQEEV SKKRTRRTHKYQRAITGASLTDIMAKRNQKPEVRKAQREQAIRAAKEKNKAKATQKPRVG GKRMKLNVSYPVTGCQKLFEVDDEKKLRNFYEKRMSQEVGGECLGDEWKGYVMQITGGND KQGFPMKQGVLTASRVRLLLSKGHSCFRPRRSGERKRKSVRGCIVDSNLSVLNLVIVKKG DADIPGLTDKTVPRRLGPKRASKIRKLFNLSKEDDVRQYVVRRPLPPRTKAPKIQRLVTP LVIQRKRHRLSLKKKRAARKRDEAAD---------------------------KVKAKEL RGKKKEDLLKQLTELKQELSNLRVAKVTGGAASKLSKIRLVRKSIARVLTVINQTQKENL RKFYMPKDLRQKKTRAMRKALTEHEKSLRTKKQQRKDRLYTTRKYAVKXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKKKKVSLKFTID CTHPVEDGIMDAASFEKFLHERVKVNGKTNNFKSKVTVTSDVAFSKRYLKYLTKKYLKKN NLRDWLRVVASAKESYELRYFQINNDEDDEEE--XXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------ELKQHKDGRSTWIAIHDQVYDVT KFLEEHPGGEEVLLEQAGGFATEAFEDVGHSTDARELMKDYLIGQIAEADR--------- --------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSHEVMSLEKI RERVLLCLKLYDKIDPEKLTLDSHFINDLGLDSLDQVEVIMAMEDEFGFEIPDAEAERLM RPVDIVQYVADKNDVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----AVVGDVLVMTKPLGTQVAVNAYQWLDVPERWNRIKLVVSEDDVRKAYQRAMFSMAR LNRTAARLMHKYNAHGATDITGFDLLG--------------------------------- ------------------------------------------------------------ ------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------SELVQKYVGEGARMVRELFEMARG KKACIIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDT LDPALMRPGRLDRKVEFSLPDLQGRAHIFKIHARSMSVEKDIRYELLARLCPNSTGAEIR SVCTEAGMFAIRARRKMATEKDFLEAVNKVIKAYAKFSATP------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------TGKTLFEALDNIDPPKRPTDKALRLPLQDVYKIGGIGTVP VGRVETGIIK------FAPKNITTEVKSVEMHHTAMDEAMPGDNVGFNIKNVSVKEIRRG NVAGDSKNNPPMEAGDFKAQVIILNHPGEIHAGYAPVVDCHTAHIACKFSELQEKIDRRS GKKLEDNPKMVKSGDAAIVLMVPQKPMCVEAFSEFPPLGRFAVRDMRSTVAVGVIKAVSK REGGQAKVTKAAQKAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPKQ ISEIKDFLLTARRKDAKSVKIKKNVKFKVRCSRYLYTLVIQDREKAEKLKQSLPPGLSVR ELKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------- ------------------------------------------------------------ -----------------------------------------------------------N IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKEVTGWGENDRGVSFTFGAEVVGKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLNSGRPVTPPRGTAKSK GKVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXMSESEIQNFSDPFADELHIHIRIQQRNGRKTLTTVQGINQEYDFKKI VRSCKKEFACNGTVVNDPQYGEVIQFQGDQRNNIATFLKKVGIEEQIKVHGFXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- -------------YGLKNIQAEEMVEFSSGLKGMALNLEPDNVGIVVFGNDKLIKEGDIV KRTGAIVDVPVGAGILGRVVDALGNPIDGKGAIEDAQRARVGVKAPGIIPRISVREPMQT GIKAVDSLVPIGRGQRELIIGDRQTGKTAVAIDTIINQKRFNEAQDEKAKLYCIYVAIGQ KRSTVAQIVKRLHDADALKYTIIVSATASDAAPLQYLAPYAGCAMGEYFRDNGKHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDNFGGGSLTALPIIE TQAGDVSAYIPTNVISITDGQIFLETELFFKGVRPAINVGLSVSRVGSAAQIKAMKQVAG SMKLELAQYREVAAFAQFGSDLDQATQNLLNRGVRLTELLKQGQYVPMAVEEQVSVIYAG VKGHLDKLEPARITKFEKEFLAHLRASQQELLTTIRKDGRITEETDAKLKECVTTFVAGF XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEYAQVSKMLGNG RLEAQCFDGKKRLCHIRGKLRKKVWINTADIILIGLRDYQDDKADVIMKYTADEARNLKS YGELPESAQIADDMDDNITF------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- ---------------------------------TQVLINCRNNKKLLARVKAFDRHCNMV LENVKEMWTETPKTGKGKKKSKPVNKDRFISKMFLRGDSVILVLRNPL------------ -------------------RCEGMNISGNFYRNRLKYLEFLRKRHNTNPKRGPYHFRAPG KIFWRTVRGMLPHKLTRGKEALDRLKAFEGIPPPYDKVKRMVVPSALKVLRLKQRRKFCS LGRLSHEVGWKYQDVVSTLEAKRKVKSNAFYLKKKSEDRLRE------------------ -NIEKGKKLFVQRCAQCHTVEQGGKHKQGPNLHGLMGRRTGQAAGYSYTDANKDKGIVWG ADTLDVYLTNPKKYIPGTKMIFAGLKKADDRSNLIAYLQDAT------------------ -----------------------EQASDFYAEHFGKMFFPSLVAYMSSXXXXAMVLAREN AVPYWRELIGPTNTLKARQTHPDCLRSIYGTDDQRNGLHGSDSQQSAAREIRFFFPDSVV EPISTGQAAKDYLAKAVNPTLLKGLT-----------------------------XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXKTTCAYHTSNKVARGRVVAVIGAVVDVQFDVGLPPMLNALEVTG RKPRLVLEVSQHLGENTVRTIAMDGTEGLVRGNEVLDTGTPISIPVGPETLGRIMNVIGE PIDERGPINAKHKAAIHAEAPEFVEMSVEQEILETGIKVVDLLAPYAKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVISLKDDTSKVSLVYG QMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIA ELGIYPAVDPLDSISRILDANVVGQEHYDVARGVQKILQDHKSLQDIIAILGMDELSEED KLTVSRARKIMKFLSQPLQVAEVFTGSEGKYVPLKDTIKGMKGVLHGEYDHLPEIAFYMV GPIEEVIQKADRLAEEQMLMPKKNRIAIYEHLFKEGVLVAKKDFHAPKHGELEVPNLHVI KALTSLKSRGYVKEQFAWRHYYWYVTNEGIQYLRDFLHLPPEIVPATLKRQPGGEDRAAY RRGAGGDKKADVGAGATXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------------- ------------------------------------------------------------ ------------------------------------------------------------ ATPVNWKPGKDLTQTSNKRSHVEMDTFFAWFSDTGDAGADELGEVIKDDIWPNPLQYYLA SEIDEEGA---------KKLTREEELLLQDFSRNVTTKSSALFYGNAFIVSAIPIWLFWR IHQMDPYVLFLVGTLVSTYLVAFAYKNVKFLLKHKVAQKREEAVSREVSKMITDDKKISK REKDERILWKKNEVADYEATTFSIFYNNAMFLVLVIGISFYLLRSFTAPFNYILTMATAS GLLALFSTSS-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXX-------------------------------------------------- ------------------------------------------------------------ ------------------------------VTDFREACCRQYEMGECAREGFCNFMHLKP ISRELXRELYGRKRNNKSKNMTSK---------SRSRSRSRDR--XXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- ----------------IYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPD DPLANDVAEQWKVNEAQAIETAKAWTRLYAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------- ------------------------------------------------------------ ---------------------KGLKLSFDTTFAPSTGKKSGKIKTSYKQDYVNLGCDVDF NFAGPTVNGAAVIGYQGWVAGYQMAFDKSQLTKNNFAVGYSTDDFTLHTNVNDGKEFGGS VYQKVSSDLQTGVQLSWHHETGTTLFGFAAKYSPDKDSTVRAKINNNSQVGLSYQQKVRD GVTLSLSSLIEGKNFSAGGHKIGLGVEFES------------------------------ ----------------------GQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKAK LRAGTRVALDMTTLTIMRYLPREVDPLVYNMSIEDPGTINYSQIGGLGEQIRELREVIEL PLTNPELFKRVGI----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------XXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXMGKFMKPGKVVLVLGGRYAGRKAIIVKNHDDGTSDKPYGHALVA GIDRYPRKVTKRMGKKKLKTRSKIKAFVKVLNFNHLMPTRYSVVNLDKSVVNKDAFRDPA LRRKARREAKMKFEEKYKLGKNKWFFQKLRFERTFIMVKPDGVQRGLVGEIIKRFEQKGF KLVSMKFMQASVEHLKKHYADLSSKGFFEGLVNYMASGPVVPMVWEGGVVKTGRVMLGET DPAKSNPGTIRGDYCIHIGRNICHGSDSVESANKEIALWFKPEELVDFTPCEKPWVYEKK PAAPAKTPVKAKEKALKAKKSVQRGNFAKRTRKVRTTVQFTLPKTLKLPRAPKYARKSIF KRTRLDQFKIIKYPLTTESAMKKIEDNNTLVFLVDKLVNKPQIKYAVKQLYDIDVAKVNV LNRPDGEKKAYVRLAPDYDALDVANKIGII---KQRMRLANDKASKNVHNRGNVPKTLKP SEDKLPVGPWLLGLFIFVVCGSAIFQIIQSIRV-------AVATWRWVADDDNCGICRMP FDGCCPDCKLPGDDCPLVWGQCTHCFHIHCIVKWLNSQQVQQQCPMCRRDWKFKEXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXRLYVKAVFTGYKRGLRNQHENTALLKIDGVIERKDTNFYLGKKCAYVYKA RNKTANPGRDKASRLRVIWGKVTRPHGNSGSVRAKFRKNLPANAMGRRIRVMLYXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPQNEHIELHRKR YGYRLDYHERKRKKESRQAHEVAKKAKKLRGIKAKLYNKKRHSEKIQMKKTLKMHEERKT KQKNKEEVPEGAVPAYLLDREGQTRAKVLSNMIKQKRKEKAGKWDVPLPKVKGVSEAEVF RVVKTGKTRRKAWKRMVTKVTYVGEGFTRKPPKFERFIRPMALRFKKAH----------- ------------------------------------------------------------ -------MAARPLISVYSEKAEPSGSSITLPAVFKAPIRPDIVNFVHNQIRMNSRQPYAV SEKAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRR VNVNQKRYAICSAIAATGVPALVMSKGHRIEQTPEVPLVLSDKVQEFKKTKEAVGLLRKL KAWPEIEKVYASKRFRAGKGKMRNRRRIQRRGPLVIYNQDNGICRSFRNIPGVTLLNVSR LNLLKIAPGGHVGRFCLWTESAFKSLDGLYGTWKKASTGKKNYNLPMTKMANTDLGRLLK SDEIQNVVRAPQKERQRRVLKKNPLKNIRTMVRLNPYAPVQKRNAIRKRVKQQQLDEKRG -----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSHRKFSAPRHGSLGFLPKKRSRRHRGKV KAFPKDDPSKPVHLTAFLGYKAGMTHIVREVDRPGSKLHKKETVEAGTIIESPPMVVVGA VGYIETPQGLRSFKTIFAEHLSEECRRRFYKNWYKSKRKAFTKYAKKWQDESGKKVIEKD FQKMKKYCKVIRVIAHTQIKLLKKRQKKAHLMEIQLNGGSIADKVDWAREHFEKTVPIGN VFATGEVIDIIGVTKGKGKKGVTSRWHTKKLPRKTHKGLRKVACIGAWHPARVGFSVARA GQKGYHHRTEVNKKIYKIGQGVHTKDGKVIKNNASTEYDITDKMITPMGGFPHYGEVNQD FVMIHGCTIGPKKRVLTLRKSLRTHTKRKALEKVHIKFIDTSSKFGHGRFQTIQEKQTFM GPLKKDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXX-------------------------------EKKKKKKKKPL DLSELEDNLPENEDSLSTKKKKLDTDRDYTYEELLKRVFDIMREKNPDMVAGEKKRFVMK PPQVMRVGTKKTS----------------------------------------------- -----------EYVTCHTCRSPDTNLQKDTRLYFLQCETCHSRCSVASIKTGFKAVTGKR AALRAKTSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQVPESLLKKRKQNEERSHEKRRVMFQRAE KYIKEYRKLEREDIRLARDARKHDNFYVPPQPKLAFVVRIRGINGIHPKPRKVMQLFRLL QINNGTFVKLNKATQHMLRIAEPYITWGFPNLKSVRELVYKRGFGKVDGKRIALTDNAII EKVLGKFGIICMEDLIHEIFTVGPAFKQASNFLWRFKLNTPNGGWKKKNNHFVDGGDYGN REDKINTLLKRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------PELKKYM DKRLNLRLNGGRKVSGILRGFDPFMNLVVDEGVEETKAGEKNNIGMCVVRGNSIVLLESV DRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXMGVKYEMAIGLYKGHKVTERKARPSRRKGTQTKKAKFIRDLVR EVAGFAPYERRAMELLRVSKDKRALKFCKKRLGTHVRGKGKREEMVQTIQQMRKAXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXX------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------L YKMMQAGKLKVPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGKVACVAGYGDV GKGCATALRAFGARVLVTEIDPINALQAAMEGYEVTTIDEAVKEARIYVTTTGCKDIITS KHFPQMLEDSIVCNIGHFDCELDVKWLNDNC-KKDTVKPQVDRYTLPSGKHIILLAEGRL VNLGCAMGHPSFVMSNSFTNQVLAQIELWTKSDQYKLGVHFLPKKLDEEVAAAHLEHLGV KLSKLSPDQASYLGIPSEGPFKPDHYRYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFKSLLETAKTSPL VSPFGLKVNEHRTIAAT-EQNSCEFGSGTYYAYCAFGGLLSCGLTHTAVVPLDLVKCRIQ VDPGKYKNIINGFRITLKEDGARGLGKGWAPTLIGYSMQGVGKFGFYELFKILYSNFLGE ERTFLYRTSLYLAASASAEFFADIALCPMEAVKVRIQTQPGWANNLREGVPKLLKEEGMF GFYKGIVPLWGRQIPYTMMKFACFERTVEALYKYVVPKPRSDCSKAEQLVVTFVAGYIAG VFCAIVSHPADTIVSKLNKEKGSTFMGVAKKLGFAAMWKGLFPRIIMIGTLTALQWFIYD SVKVYFRLPRPPPPEMPESLKRKLEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XX---------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------------------GMG MYNTDESIRGFAHSCFQYALKKKWPLYMSTKNTILKRYDGRFKDIFEEIYQSTYKKDIEN AGIWYEHRLIDDMVAQGLKSSGGFVWACKNYDGDVQSDVVAQGYGSLGLMTSVLMCPDGK TIEAEAAHGTVTRHYREHQKGNPTSTNPVASIFAWTRGLEHRATLDGTPDLARFCQTLEK ACIDTIDSGKMTKDLAGCIYGLKNVKPEHYLYTMDFLEAIAEELEXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------- -----------------------------------------GGAPTSGAKQAA------- -AAADDDDDVDLFGSEAEKLKQQRLKEYNERKAKTVIAK------------XXDMKAMEE KVRSIQMDGLLWGVCKLVPV---------------------------------------- -----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------RKLRECETVLVNDFFLVACLDDFVENARLFIF ETFCRIHQCISINMLAEKLNMSPEDAERWIVNLIRNARLDAKIDSKLGHVVMGTKAVSPY QQVIEKTKGLAFRSQMLAMHIEKKL----------------------------------- -------------------------IRGWDEGVAQMSVGQRAKLTCTPDYAYGDRGFPGA IPPNSTLVFDVELFSI-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXX----------------------------------- --------------------------------------------------SVKHEQKIDC GGGYVKVFDSSLEQKDMHGDSPYYIMFGPDICGYSTKKVHVIFNYKGKNLLTKKDIKCKD DELTHLYTLIVRSDNTYEVKIDNEKVESGELEADWDFLAPKNIKDPDAKKPDDWDDKEKV DDPDDKKPEDWDKPQHIP---------WDEEMDGEWEAPQIDNPEYKGEWKPKQIDNPNY KGKWVHPEIDNPEYAPDDKLYKYDDIGALGLDLWQVKSGSIFDNFLVTDDEDYAKKHGEE TWGTLKDGEKKMKEDQDEVERKKQEEEDKKRKEEEDSKGDEEEEXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDFEVDEEGDQGLLKL KEKVRKRKGRGFPTKSGVQEYEGMDI-GPGPQRSVEGWILFATNVHEEATEDDIQ----- ------------------------------------------------------------ ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTFLFTSESVGEGHPDKICDQV SDAVLDAHLKQDPYAKVACECASKTGMIMLLGEVSSTARVDYQSIVRETVKHIGYDDSRK GFDYKTFNLLVALEEQSCDIADGVHTGRDDEDIGAGDQGLMFGYATDETEESMPLTVVLS HQLNAKMAELRRSGDLAWARPDSKTQVTIEYSMDGGACIPVRVHTVVISIQHDEEVTVEQ LRKELMEKVVKVVIPEKYLDDKTVYHLQPSGRFVMGGPQSDAGLTGRKIIVDTYGGWGAH GGGAFSGKDFTKVDRSAAYACRWVAKSLVKAGLCRRVLVQVSYAIGIAEPLSVFLTTYGT GTKSDDDLLKIIHKNFDLRPGAIVHELDLRHPGYQKTACYGHFGRPEFTWETPKKL--XX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------- -----------------------------------KAFRKAAGKELTVDPALEFEKRRNV PVKYERELWQNTVKAMQRIEEIKAKRQNQFIINRLKKGKELRKEADIKEVEKNIHLIRAP A----------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------Q RVLIAAHGNSLRAMVKYLDNMSDADIMGLNIPXXXXXXXXLDANLKPIKHYYLASEEQVK AAVAKVANQGKAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXMGIDIKHKHDRKVRRTEPKSEDIYLRLLVKLYRFLARRTNA KFNKIILKRLFMSKNNRPPLSLARLVRNMKKPGRESKIAVCVGTVTDDLRIYKVPKLNVV ALRVTERARARILKNGGTIMTFDQLALKSPKGKNTVLIQGPRKAREAYRHFGPAPGVPHS HTKPYVRSKGRKFERARGRRASRGYKNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKSPEAVEGRKHMDVQT ELYLEELSDRVEEADVEVQTDAFLDRPPSPLFVPAKSGQDIETQIYEGDLFDFDTEVKPV LEVLVGKTVEQSLLEVMEEEELANLRSQQRAFQELRNAEMVEQQRLEEQERRHREEKERR MKQQREILRKEKETSDKIAARAFAQSYLSDLVP----TLSDHGYFYDPVERDVEQGFLPW LMDKVEGSIDHQVMGRVVLDGLLREVVKNRGELYDKMKARGELKEYKVIGRRLPSDKERV PPLYQLRIFAPDKPTAKSRFWYFVGLLKKMR--------------KXPQMIKNFGIWLRY VSRSGIHNMYREYRDLTTAAAVTQCYADMGARHRARASSIHIIRVEVIVSSKCRRNHVKQ FHNSKIKFPLPHKVSKRLHYPRFTTNRPHTHY---------------------------- ----XLAHRITGVTMGVVLYSLSISLAVA------------------------------- ---------------------------------------XXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMIIYKDLITNCELLTDAYPDGILTVKCK--QLSGSNPSSGINVVLADKKNYLACVKA YIKKLESWEFYQGLVLLSWDTPYLYYFKDGLEAEKV------------------------ ------------------------------------------------------------ ----DQLTAGIICAGWDKSKGGQVYMIPLGGMCERLPFGIGGSGSMYVYGYVDSQFKENM TKEECLKFTANTLALAMARDGSSGGIIRLAAITKDGVE------------XXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXX--------------------------------------------------- ------------------------------------------------------------ ------------------------------CNEQLYGMCESLWEPDLGPDDLFETISQAL LNAVDRDAVSGWGAVVHIIEKDKVTTRTLKGRMDXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMVR EDKSTWKSNYFLKIIQLFDEYPKCFVVNADNVGSKQMQQIRVSLRVLMGKNTMMRKAMRG HLENNPALEKLIPCIKGNVGLVFTKLDLSDIRDKIKENRVAAPAKAGAFATVDVWVKAQN TGLGPEKTSFFQALQIPTKIARGAIEILNDVHLIKEGDKVGASEATLLNMLNISPFTYGL NIEKVYDSGTVFDPKIMDITDDDLCRRFMESVANIASISLSIGYPTTASAPHTIINGFKN LLAIAAETEIEFKEAETMKEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXX----------------------------------------- --------------------------------------------DKVAEWKAAFEKFDTD KSGMISRREVVDLL-LGLGYDDDDA---KAIAYTIMKADTSGDGKISWDEF--------- --------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXARMVTKQIGGDKNGGTR TVRVHRMPKFYATEDRPRKLPSAFSEHKRHLRAGITPGTVLILLAGRHKGKRVVFLKQLA SGLLLVTGPFAINACPLRRINQIYVIATKTKLDVSKVTLSDTLNDDYFRRQKVRKQKQAE GEIFDTKKEEYKVSDQRKADQKTVDEGVLAAVRAHPDKKLLFGYLGAMFSLGNKQYPHKM VFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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------------------------------------------------------------ ------------------------------------------------------------ -GATTRGGTQKWDSTLGHATPGTATSSRESTLTHTDTPEHGINWAEE------PHTGCRS GNLIQKT------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------- ------------------------------------ACTSQVTRLCDLSCDGDPVTSVSW SDRGNLVAVGTHKGFVQIWDVAASKRISVLEGHSARVGALAWNADTLSSGSRDRLILQRD IRTPAVMPERKLTGHRQEVCGLKWSPDHQHLASGGNDNKLFVWNMTS------------- ---------------------------------------------CNLAWSKHANELVST HGYSQNQILVWKYPSLVQIAKLTGHTYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTR STKESKS---------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------------- ----------------------------------PSTHNMDVPNVSRIEYSVIGMKDEYF QLMDSSYETREDLKFLAQVLSAMGQECV-------------------------------- ------------------------------------------------------------ ------GEFREPSGVTVDSEGHIVIADSKNDRIQVFHPDGRFAAQVKIVRPSDIHLHDDR FLLVDNLLQHNVKVYE--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX---------KDAGVDGVVTFNQEAGTVVSGTIKGLAPGKHGFH VHEFGDNTNGCTSAGAHFNPAGLTHGAPEDKERHAGDLGNVTAGTFEIKDSQIPLTGERS IIGRTVVVHADIDDLGKGGHELSKTTGNAGGRQACGVIGITKMVNFTVDQIRGIMDKKRN IRNMSVIAHVDHGKSTLTDSLVSKCGIIAASKAGEARFTDTRKDEQERCITIKSTAISLY YELDKKDMCNGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDSKSGVCVQTETVLRQA IGERIKPVLFINKMDLILLTLQLEPEDAFQNFQRILETTNQIICTYGDDDGPMGDIQVEP SKGTVGFGSGLHGWAFTLKQFAEMYASKFGIDVAKMMKRLWGENFFNGVRGFVQYVLKPI YQVFHICMEHSKALAMAEKMSIKLSSDDKQLREKQLLKVMMRLWLPAGDALLQMITIHLP SPVTAQRYRTELLYEGPKDDDVAIAMKECNPEGPLMMYISKMVPTTDKGRFYAFGRVFAG VCSTSRKVRIMGPNYVPIKTIQRTILMMGRYIEPIEDVPCGNICGLVGVDQFLVKTGTIT TFDDAHNLRVMKFSVSPVVRVAVECKNPSDLPKLVEGLKRLAKSDPMVQCTIEESGEHIV AGAGELHLEICLKDLEEDHAQIPLKKSDPVVSYRETVAEESDRMCLSKSPNKHNRLFMKA QNMPEELSQDIDRGDVDSKQEAKERARYLADKYDYDVTEARKIWCFGPESTGPCLVVDCT KGVQYLNEIKDSVVAGFQWATKEGVLCEENMRGVRFNIHDVTLHTDAIHRGGGQIIPTAR RCLYACVMTAQPRLLEPVYLVEVQCPEQAMGGIFSTLNNRRGHVFEQLQVANTPQWIVKG 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXPKVGINGFGRIGRLVLRSALLAVEVVAVNDPFIPLDYMVYMFKYDSVHGR FPGKIELYVDGKAIQVFDKKSPNEIPWGSTGAEYVVESTGVFTTNEKANLHIQGGAKKVI ISAPSADAPMFVMGVNQEKYDPSMNIISNASCTTNCLAPLAKVINDNFGIESGLMTTIHA YTATQKTVDGPSGKAWRDGRAAAQNIIPASTGAAKAVGKVIPDLNGKLTGMAFRVPVPDV SVVDLTCVLKKPAEYDAIKKVVKGPMKGYLAYTEDQVVSSDFIGDRNSSIFDARAGIMLT PTFVKLVSWYDNEFGYSCRVVDLIQYIY---XXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXX---------------------------------------------------- ----------------------------------------------DKTAKVWDLNSNQA VQVAQHDAPVKCVKWIKAPTYSCLMTGSWDKTLKFWDTRSPNPMLTVNLPERCYCGDVLY PMAV-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------EDRAKLDGMYECILCACCSTSCPSYWWNGDKYLGPAVIMQAYRWVMDSRDDY TEERLDKLRDKWSVYRCHTIMNCTKTCPKGLNPGAAIAEVKKLLAGQESTGIPRQXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------- -------------------------------------------------EGLFPVILGHE GGGIVESIGEGVTSVQPGDHVVPLYIPQCNDCKFCHSKKTNLCSKIRGTQGKGVMPSGTS RFTCKGKSLYHFMG---------------------------------------------- ------------------------------------------------------------ ----------------------------------------------------------QL VTGRTWKGTAFGGWKSRDSVPKLVDDYLKGVVKVDEFVSHNFPLDKINEAFDLMHAGKSX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------KGLHSQLEDVNRYLDKVATSKLPINHQI VYQLQDVFNLLPDVNLLSFVKSVYVKTNDQMLVVYLASLIRSIIALHNLISNKLANRDAE KGESKPKEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------- ------------------------------------------------------------ ----------------------------------------------------------TV PISSEIFKRKGVYDPKRIFGVTTLDVVRANTFIAEAKNLDVTEVNVPVVGGHSGVTIVPL ISQATPPVSFPQSEREALSTRIQNAGT--------------------------------- 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----------------------------------------------------------MP DSYSFGIEPITCHAFNKDRTKIAIPNNHEVHIYKLAWVKESTLEEHAQRVTGIDWAANSN RIVTCGADRNGNVWPVLVILRINRAATCVKWSPREDKFAVGSGARLISVCYFEEDNNWWV SKHIKKPLRSTVTSLDWHPNNVLLAAGSTDFKTRVFSTYIKEVEEKPSATNWGQKMSFGN MMAEFSSGGGWVHDVSFSDSGDRLAWVGHDASVSVADAYVKTNFLPFSAISWVAENSLVV AGHHCYPPLFTFDGGQGAF----------------------------------------- -----------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX >Phoronis_muelleri MTDRKAVIKNADMSEDMQQDSIDCATQALEKFNIEKDIAAFVKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSG-----RLFQTSATKNDIDQAAKYIGAGAATV GAAGSGAGIGSVFGNLVIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLILFAFM SHFKD-AKAPEATIHRIRITLTSRNVKSLEKVCSDLIKGAKDKNLKVKGPVRMPTKTLRI TTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSKRGRGGT SGGKFRISLGLPVGAVMNCADNTGAKNLYVIAVHGIRGRLNRLPAAAAGDLVVATVKKGK PELRKKVMPAVVIRQRKSIRRKDGVFLFFEDNAGVIVNVKGEMKGSAITGPVAKECADLW PRIASNASSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGKPRGLRTARKMRNHRREQRWHDKD YKKSHSSTKWKANPFGGASHSKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP NDGCLNYIEENDEVLIAGFGRKGHAVGGIPGVRFKVVKVASVSLLALYKEKKERPRTXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPKI PLKMSKTYTTPRRPFEKERLDQELKLIGEFGLRNKREVWRVKYTLAKIRKAARELLTLEE KDPKRLFEGNALLRRLVRIGVLDESKMKLDYVLGLRLEDFLERRLQTQVFKLGLAKSIHH ARVLIRQRHIRVRKQVVNIPSYVVRLDSQKHIDFSLKSPYGGGRAXRVKRKNSRKGAGGD DDMGNSFTNLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYLQNTQGLIFVVDSNDRERVGEARDELMRMLAEDELRE AVLLIFANKQDLPNAMNAAEITDKLGLHSLRNRNWYIQATCATSGDGLYEGLDWLSNQLK NAKMPLAKDLLHPSVEEEKRKCKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRRK--MVRMNVLADALKSICNAEKRGKRQVLLRPSSKV IIRFLQVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVALRDMEKWTTNL LPSRQFGFIVLTTSGGIMDHEEARRKHLGGKILGFFFXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXX--EMPSIQLFGKWASDEVQVNDISLQDYIPVKDKYAKYLPHSAGRYQVKRFR KTQCPIVERLTNSLMMHGRNNGKKLMAMRIVKHAFEIIHLLTGENPLQVLVDAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREAAFRNIKTIAECLADELINAAK GSSNSYAIKKKDELERVAKSNRQSEQMTLRGTLTGHRGWVTQIATSSQNPDTLLSCSRDK TLIAWQLNRDTTYGYAKKCLTGHNHFVSDVVVSSDGQFALSGAWDKTLRLWDLNAGVTTR LFQGHTKDVLSVAFSSDNRQIVSASRDRTIRLWNTLGVCKYTIDDNHTDFVSCVRFSPNT MNPIIVSAGHDKIVKVWNLANCRLKT---------------------------------- ------------------------------------------------------------ -----------------------------------XXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXMSDAEGDDTTTQAASGGPMDVSTALQEVLKTSLISNGLARGLHEC CKALDKRTAHLCVLANNCDEGAYTKLIEALCREHGIPLIKVDDNQKLGEWSGPCKIDKEG KPRKVVRCSSVVIKDYGTETMALDIVNNHLK---MTTVRKKLVIVGDGACGKTCLLIVFS KDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSI DSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEATKRELMKMKQEPVRPEEGRA MAEKISAYAYLECSAKTKECVREVFETATRAALQTKKKKRAXMDDFQSAEETTFVVDEVS NIIKESIEGAIGGNAYQHNKVNQWTSNVVEQCLNQLTKLGKPFKYIVTCVIMQKNGAGLH TASSCFWDNATDGSCTVRWENKTMYCIVSVFGLTIMCTVTTKMQKPSGEKPDEFESSISQ AILELEMNTDLKANLRELHISGAKEIDVQGKKAIIVFVPVPQLRAYQKVQSRLVRELEKK FSGKHVVIIAQRRILPKPTRKTRTKNKQKRPRSRTLTAVHDNILEDLCFPSEIVGKRMRV KMDGSRMIKVHLDKLQQTNVEHKLDTFTAVYKKLTGKDVSFEFPEYVL-TGEFRGGFGGR GRGRGRGRGRGKE-DKEWMPVTKLGRLVKDGKIKSLEEIYLFALPIKEAEIIDFFLGPSL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDYNGHVGLGVKCSKEVATAIRGAIVLAKLSI VPVRRGYWGNKIGKPHTVPCKVHGKCGSVHVRLIPAPRGTGIVSAPVPKKLLQMAGVEDC YTSAAGQTATLGNFAKATYAAIGKTYSYLTPDLWKETVFXKSPLQEFTDYLAKMSGGLDA LALKEEDVTKFLACGTHLGANNVDFQMESYVYKRKPDGVFIINLRKTWEKVLLAARAIAA IENPADVCVISARPYGMRAVLKFAAATGASPIAGRFTPGTFTNRIQAAFREPRLLIVTDP RQDHQPITEASYVNIPVIALCNTDSPLRYVDIAIPCNNKGVHSIGFMWYLLAREVLRLRG TISRQTPWDVMPDLYFYRDPEEAEKX---------------------------------- -------MKFNKMVSSTRRKQRKRHFSAPSHIRRKIMSSPLSKDLRQKYNVRSIPIRKDD EVQIVRGHYKGPQVGKIVQCYRKKFVIHIERIQREKANGASVHVGIHPSKVVIVKLKLDK DRKQILERKARSRQVGKHTEESIAAPSSTSVGSTVRQRKTATGAGGGAGMWRFYTEDSPG IKVGPVPVLVMSLIFIASVFMLHIWGKYSRGXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXEKKDDFIINSKYKLVRKIGSGSFGDIYLAVDT SNPSEVAVKLEPKKARHPQLLYESKLYKILQGGVGIPCCKFFSHKDYNILVLDLLGPSLG DLFNFCSRRLTMKTVLMLADQMIGGIEYVHNKNFIHRDIKPDNFLMGIGRHCNKVFIIDF GLXKKYRDPRTRQHIPYREE-NLTGHARYASINAH------------------------- ------------------------------------------------------------ ------------------------------MNAEKLKQRTGGKGSVRRKKKVVHKTATTD CKKLQNSLKKLGVNNIPGIEEANMIKDDGHVIHFNNPKVQASLAANTFAITGHAETKAIT ELLPGILNQLGAESLTNLRKLAESTEDVD-DDEDVPQLIGNFDDASKGEMTRYSSDPENA TKSAKARGSHLRVHFKNTRETAQAVKRMHLRRAQKYLKNVIDKKEIIPFRRFNGDVGRKA QCKQFGTTQGRWPKKSAEFLLQLLKNAESNAEYKGLDTDHLVIEHIMVNRAPKMRRRTYR AHGRINPYMSSPCHIEVILAEKEVAISKPAKKKVSQKKLKREKLMARDKKTGPKPELTEE QKQEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIADIDKEGTGTIDFNE FLNMMTMKMSEKDSKEEILKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQEADRD GDGEINEGEFLRIMKKTSLY---------------------------------------- ----------------------------------QTRIIDVVYNASNNELVRTKTLVKNA IVHIDATPFRQWYETHYATPLGRKKGAKMSEEEEAQINTRSKKTEKKYEERKKVAAVEQP MEDQFTTGRLYASISSRPGQCGRADGYILEGKELEFYMRKLKAKKG-MSLVVPEKFQHIL RVMNTNIDGKRKIMFAMTAIKGIGRRYAHVVLKKADVDLAKRAGELSEEEVERVITIMSN PRQYKIPDWFLNRQKDVKDGKTSQVMSNGLDNKLREDLERLKKIRAHRGLRHYWGLRVRG QHTKTTGRRGRTVGVSKKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKWEY KEEHPFEKRRAEGEKIRKKYPDRVPVIVEKAPKARVGDLDKKKYLVPSDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGALYQEHHEEDYFLYIAYSDESVYGMRELRIGKL CLNICVGESGDRLTRAAKVLESLTGQQPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAE EILEKGLKVREYELRRGNFSSTGNFGFGIQEHIDLGIKYDPSIGIYGMDFYVVLRRPGFS VSNRRKKRSRIGFSHKVYKEESMKWFQQKYDGIILPGKXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQNERAFQKQPTVFLNKKRTLLLRYHK SVGLGIKTPREAIDGNYIDKKCPFTGNVSIRGRILTGVVTKMKMMRTIVIRRDYLRYIKK YNRFEKRHKNISAHLSPAFRDVKPGDVVTVGECRPLSKTVKFNVIKVTKGQGNKKGFEKF XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRVIRSQRKGPGS VFKAHTKNRKGAAKLRAVDFAERHGYIKGVVKDIIHDPGRGAPLARVVFRDPYKYKLRRE TFIACEGMYTGQFVYCGRKATLQIGNVLPVGTMPEGTIVCNVEEKTGDRGRIARASGNYA TVISHNPDTKRTRIKLPSGTKKVVPSANRAMVGIVSGGGRIDKPMLKAGRAYHKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGMGVTVRRDTSAGRKSG------------------ -AKRTKKVGITGKYGTRYGASLRKMIKKIEISQHSKYTCHFCGKENMKRSAVGIWQCKSC KKKVAGGAYVYSTTAAASIRSAIRRLRETKDMGRRPARCYRYCKNKPYPKSRFCRGVPDA KIRIYDLGRKKARVDEFPLCIHLVSDELEQLSSEALEAGRICANKYMVKFCGKDSFHIRI RVHPFHVLRINKMLSCAGADRLQTGMRGAFGKPQGTVARVRIGQPIMSIRSRENNKESCI EALRRAKFKFPGRQKIYLSRKWGFTKWDREVYEEMRAEGRLIPDGVTVQYKRTHGPLAAW KKTQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGAYKYIQELWRKKQSDVMR FLLRVRCWQYRQLSSIHRAPRPTRPDKARRLGYRAKQGFCIYRVRVRRGGRKKPVPKGAT YGKPTNMGVNQIKFARSHQSVAEERVGRKCGGLRVMNSYWVAQDSTYKFYEVILVDPFHK AIRRNPDTQWITKSVHKHREMRGLTSAGKKSRGLGKGHPFHATIGGSRTKNWKNRQALSL RRKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXLGFAENFALSGAAAIISKTAAAPIERIKLLVQNQDEMIKQGRLERPYKGVIDCTM RTYQSEGVLPFWRGNLANCIRYFPTQALNFAFKDKIKAMFKPKKTDSQALNFSKNIASGG LAGTASLFFVYHLDYCRTRLANDAKAATKREFNGMVDVYRKTLASDGISGLYRGFVISAX GIFVYRGCYFGFYDTLKPIVLGEEAPVCLSF----------------------------- ---------------------------------------------------------XXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXMVRGPRKHMKRLNAPKHWMLDKLGGVFAPRPSTGPHKLRECLPLMVFLRN RLKYALTYDECKKIVMQRLIKVDGKVRTDFCYPAGFMDVITIEKTGENFRLIYDVKGRFT VHRITKEEAGYKLCKVRKVYTGPKGVPLIVTHDGRTIRYPDPMCKVNDTVQVXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXNEFHLRYYIGHKGKFGHEFLEFEFRPDGKLRYA NNSNYKNDTMIRKECFVHKSVLEELKRVIEDSEVMQEDDTLWPGADRIGRQELEIVIGDE HISFTTSKIGS-VDVNQSKDPEGLRTFYYLVQDLKCLVFSLIGLHFKIKPIMAPTKKSKK TIESINARLALVMKSGKYVLGYKQTLKTLRSGKAKLIIIANNTPPLRKSEIEYYAMLART GVHHYNGDNIELGTACGKYFRVCTLSITDPGDSDIIRSMPAG------------------ ------------------------------ETCLLDILDTAGQEEYSAMREQYTQSGDCF LVVYDVTSPQSFEEARHMFTFIQRIKHKSGVSMV-------------------------- ----------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLKVELCT FSGYKIYPGHGKRICKVDGRTFQFLSGKCEKSFSMKRNPRKINWTVLYRRKHKKGISEEV SKKRTRRTTKFQRAITGVSLGDIIAKRNQKPEVRKAQRDQAIRAAKEKQKVKEKAAPRVG GKRMKLNISYPATGCQKLLEVDDDLKLRAFYEKRMASEVSAESLGDVWKGYVVRISGGND KQGFAMKQGVLTTGRVRLLLSKGHSCYRPRRSGERRRKSVRGCIVDSGLSVLNLVVVKKG EQDIPGLTDKTIPRQLGPKRASKIRKLFDLQKDDDVRQYVVRRPCPPRSKAPKIQRLVTP VVLQRKRHRVAXQKRRAAKQREDAADYQKLLA---------------------RVKAREL RGKKREELESELERQRQELLALRVSKVTGSNVAKISKIRDVRKSIARISTVINQTQKENL RKFYKPIDLRMKKTRAIRRALNKHESSITTAKFQARQRAFPVRKFAIKAAKTGPKVTDIV TFNITIGGEEIGSIEIGLFGKTVPKTAANFKALATGE-GYKGSKFHRVISDFMIQGGDFT RGDGTGGKSIYFADENFKQKHNGAGWLSMANAGKDTNGSQFFICTVKTPWLDGKHVVFGK VLKGMDVVRKIEKTPKGGDKPKKDVVIADCSAREVEEPFAVSKEPSTEKKKKIAIKYSID CTHPVEDGIMDCASFETFLKERIKVAGKTGNLKSKVIVTCEIKFSKRYLKYLTKKYLKKN SLRDWLRVVATNKESYELRYFQINNEEEEAEED-XXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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REHMLLAFTLGVKQLIVACNKMDSTEPPYSEARFNEIVKEVGNYAKKVGYNPKNVAFVPI SGFHGDNMLKTKWFKGWSVASGTTLFQALDSILPPKRPTDQPLRLPLQDVYKIGGIGTVP VGRVETGIIKPGIICTFAPAGLSTEVKSVEMHHESLTEAVPGDNVGFNVKNVSVKEIKRG MVAGDSKNDPPKGANSFVAQVIVLNHPGEIHAGYQPVLDCHTAHIACKFAELKQKIDRRS GKVLEENPKMVKSGDASMVKMVPSKPMCVESFSQYAPLGRFAVRDMKQTVAVGVIKSVEK AE-AGGKATKSAVKAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPKH IVEIKDFLLTARRKDAKSVKIKKNVKFKVRCSRYLYTLVIQDKDKAEKLKQSLPPGLAVK ELKMSKVTREGLTEAVTQVLAKKRKFSETVELQISLKNYDPQKDKRFSGTVKLKFVPRKK LRVCVLADQQHMDEAKANDVPCMTVDDLKKLNKNKKLVKKLAKKYDAFLASDSLIKTIPR ILGPGLSKAGKFPSTLTHSESMTSKIEDVRATIKFQMKKVLCLAVAIGNVEMPPEHLVSN INMAINFLVSLLKKNWQNVRALYIKNTMGPAVRVYXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDQDIQSLVLEIVGTNVSTT YITCPSDPKQTLGIKLPFLVMIIKNLKKYFTFEVTVLDDKNVRRRFRASNYQSTTRAKPF ICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDEL PAEFKLYLPVQKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXSARVTAAMARQLPRLANKVNALGAGFVAASKFSTSAEVSSILEERILGTEKADLEET GRVLTIGDGIARVYGLKNIQAEEMVEFSSGLKGMALNLEPDNVGVVVFGNDRLIKEGDIV KRTGAIVDVPIGEGLLGRVVDALXNPIDGKGPIPGATRARVGVKAPGIIPRISVKEPMQT GIKAVDSLVPIGRGQRELIIXDRQTGKTAVAIDTIIN----------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MESLYSIPFSVLECPHLKLKKPSWVKMPSAMFMFALVLLTYFLITGGIIYDVIIEPPSIG STTDERGNSRPVAFMPYRVNGQYIMEGLASSFMYTLGGLGFVMLDQCNSPLTPKLNRILL LSVASVSILISFFTLRVFMRMKLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEYAQVQKMLGNG RLSAFCFDGIPRLCHIRGKLRKKVWIVQGDIILIGLRDYQDTKADVILKYSPDEAKNLKA YGELPETVKVEEEMDDAIAFDEIDDILVRFLMKLSHETVTIELKNGTQVHGTITGVDVSM NTHLKAVKMTIKNRDPVQLDTLSIRGNNIRYYILPDSLPLDTLLIDDAPKKAGRRTTMQK PKSEMTQEELSQREQEEFNTGPLSVLTQSVKNNTQVLINCRNNKKLLGRVKAFDRHCNMV LENVKEMWTEVPKTGKGKKKSKPVNKDRYISKMFLRGDSVILVLRNPMXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXD GDAEKGAKVFKSKCAQCHTIEKGKPNKTGPNLHGFYGRATGQASSFSYTEANRTKGITWS RETLMVYLENPKKYIPGTKMIFAGIKKKQERIDLITYMEKMSKXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXRALPTYYSTKRTAVGKIVSVIGAVVDVQFENELPPILNALEVEG RSPRLVLEVAQHLSESTVRTIAMDSTEGLVRGNVCKDSGTPIRIPVGPATXGRIINVIGE PIDERGPVHAEVFLPIHQEAPEFVNMS--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------MLMPKKDRIAIFEHLFKEGVIVAKKDYQLAKHPELEVRNLYVI NALRSLKSKGMVTEQFAWRHYYWYLTNEGIQYLRDFLHLPPEIVPSTLKRQ-PTGDRAEY RRG-SGDKKADTGAGANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX MTNPTGVRRGTRYMFSRRFRHKGVTLLSRYLKVFKRGDIVDVKGDGAIQKGMPHKIYHGR TGVIYNVTPHAVGVIVNKRVCGRIIPKRINVRIEHVKHSNCRLDFLKRVNENENKKAEAK KEVHCKRIPAQPRGSHTVRTRYNKPQFLTPIPYEFIAQSRSHYKQMSPDEPSMNWADVTD RAAVTAFWNELFSGMFVAASHLLKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAICPAQAITIEAEEREDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEF STETHEELLYNKEKLLLNGDKWEAEIAANLQADHLYR-----KMRKIDENSEGDDDLETQ RSLENIDSCQQEIDTLNEKASEEILLVEQKFNKMREPHYKKRNIIIEQIPRFWLTTFVNH PQISAVLEEEEEDCLYYLKQVEVEEFEDIKSGFKISFHFDENPYFENKVLCKQFHLGTAE ATXIKWKPNKSLVSEEXQRRGFHIRTFFQWFLDTSEPSADDIAEVIKDDMWPHPLQYYLA PN---DANDD-------KKLTKEEELLLQDFSRNVSTKSSALFYGNAFVVSAIPLWLFWK IHMMDVYIIFAVMTLVSTYLVALAYKNVKFVLKHKVAPKVEDAVSKEILKKVADDKKMSK KEKDERILWKKNEVADYQATTFSIFYNNALFLLLVVIASFFVLKTFNPTVNYVMTMVGAS GLIALFSTSSK------------------------------------------------- ------------------------------------------------------------ -------------------------------SLLFMETSAKTAMNVNDIFLAIAKKLPKS EQGVNLTEQNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--DNDLLDYED-EEAQEKDVKGTYVSIRSS GFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILSMDVLCQAKSGMGKTAVFVLATLQ QLEPVDGEVSVLVLCNTRELAFQISKEYERFSKYMSSCKVAVFFGGMPIKHDEEVLTKNC PHIVVGTPGRILALCHKAIWKKGQHFVLDECDKMLEKLDMRRDVQDIFRATPHEKQVMM- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------PPGYGDLG KSARDVFNKGYNYGVWKLECKTKTSSGVEFKTEGTSNTDSGKVFGNLETKYKLADYGLTF SEKWSTDNVLGTEITIEDQLTKGLKLAFDTTFQPATGKKSGKIKTSYKREYVNTNCDVDF DFAGPTVNGALTLGYNGWLAGYQMAFDKSKLTKNNFAVGYDGGDFTLHTSVNDAXEFGGS IYHKVNSDLETGVMLSWTAGSNATKFGLGX------------------------------ -------------------------------SQREKVLADYRKKLLEHKELEARLKEMRE QLRELTKQYDKSENDLKALQSVGQIVGEVLKQLTEDKFIVKATNGPRYVVGCRRQLDKTN LKAGTRVALDMTTLTIMRYLPREVDPLVYNMSSEDPGTISYSSIGGLGEQIRELREVIEL PLMNPELFQRVGITPPKGCLLYGPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIGES ARLIREMFGYARDHQPCIIFM--------------------------------------- ------------------------------------------------------------ --------------------------------------------------------MPEN LGSVVCKFYNEYMSSTPKKLKIIDAYLAYIMLTGIMQFVYCCLVGTFPFNSFLSGFISCV GSFILAACLRLQVNPENKADFQGISPERAFADFVFTHIILHLVVVNFIGSLATPNQLLPL ELVDKCVGSKIHLIMESDKEILGTLLGIHHFVH--------------------------- ---------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXERTFIMIKPDGVSRGLVADIIKRFEQRGY KLVAMKMMTASKDHLEQHYGDLKAKPFFTGLVKFIGSGPVVPMVWEGDVVRVGRVMLGAT NPLESLPGTIRGDYCIDVGRNICHGSDSVESARKEIALWFKDEELNDWKPSTNDMVYEXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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------------------------------------------------------------ ------MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLG LWDTAGQEDYDRLRPLSYPQTDVFLICFSLISPASFENVRAKWYPEVNHHCPSTPIILVG TKLDLREDKETVEKLKEKKLSPITYPQGLSMA---------------------------- ------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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EVSGFAPYERRCIELLKVSRDKRALKFVKKRLGSHMRGKRKREEMSKVIQQMRKAXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------------- --------------------------------------------------FRTITSSYYR GAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNTLLVGNKCDLTTKKVVDYTTAKEY ADQLGIPFLETSAKNATNVEQAFMTMAAEIKNRMGPPTAAPNVKINASTPVSQKSGGCCX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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TDEEYIWCVDQTIYWPDGKPLNMILDDGGDLTNLVHEKYPKLLDGIKGLSEETTTGVHNL YKMLAKKTLKVPSINVNDSVTKSKFDNLYGCRESLIDGIQRATDVMLVGKVACVA----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------TVEEPLDLVRLSLDEKIYVKMR ND-ELRGKLHAYDQHLNMILGDVEETVTTVEIDEETYEELYKSTKRKIPMLFVRGDGVVL VSPPVRAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXHWAAERVAAVSLIGLIPAAYFLAMDYILAGIVLHT HWGVDGVSTDYVHMSATAFYGLCYFNYNDVGVTKAIKMLW---XXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLQPHLSKQ DLTTLDVSKLTPETPEVISRQATINIGTIGHVAHGKSTVVKAISGVQTVRFKNELERNIT IKLGYANAKIYKCDNQQCPRPSCYRSFGSSKEDSFPCDRAACGRFKLQRHVSFVDCPGHD ILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQ AKDQYEQILKFVPGTVAEGAPVVPISAQXKYNIEVICEY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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LALKEEDVTKFLACATHLGSTNVDFQMEQYCFKRKPDGTYIINLRKTWEKLLLAARAIAA IENPADVCVISARPYGQRAVLKFASATGSTPIAGRFTPGTFTNQIQSAFREPRLLVVTDP RTDHQPVTEASYVNIPVIALCNSDSPLKYVDIAIPCNNKGAYSIGLMWWLLAREVLRLRG TISREVPWDTMVDLYFYRDPEEAEKEPQVDDWGNEAAVPAVPITTEDWSASTTSDWS--- -------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXCSKSEFLVNGKYRLVRKIGSGSFGDIYLGINI SNGEEVAVKLESHKARHPQLLYESKLYKILQGGVGIPHIRWYGEKDYNVLVMDLLGPSLE DLFNFCSRRFTMKTVLMLADQMIGRIEYVHNKNFIHRDIKPDNFLMGIGRHCNKVFLIDF GLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRGS LPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLR QLFRILFRTLNHQYDYTFDWTMLKQKAAAAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMARYSSDPENA TKSAKARGSHLRVHFKNTRETAMNLKKMHLHKAVRYLKNVTNKKECVPFRRFNGGVGRCA QAKNFKTTQGRWPQKSAEFLLQLLKNAESNAEYKGLDTDHLVIEHIQVNRAPKMRRRTYR AHGRINPYMSSPCHIEVILAEREQAVAKPAKKK----------------------QLSQQ EITDLRLVFEVFDMNADGLIGPIELRKAMKALGFKLNREEARQMITEASLKGRSQLDFNE FLDVVIERQGDRDIRDEIMHGFKMFDYDNTGNISLDNLKHACKDSGVKFTDRELIEADIN GDGIVDKDEFVKVMLKTNLFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSLVIPEKFQHIL RVMNTNIDGRRKIPFAITAIKGIGRRYAHVVLKKADVDTTKRAGELSDEDVDKVITIMSN P----------------------------------------------------------- -------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRVRTK TVKKAARVIIEKYYTRLGSDFHTNKRICEEIAIIPSKKLRNKIAGFVTHLMKRIQRGPVR GISIKLQEEERERRDNYVPEISAIEEVDPDTKEMLKLLDFGNIPGLQVTQPIQTT----- -------------------------------------------------------YFLIR KRIHLRPEDALFFFVNNVIPPTSATMGALYQEHHEEDFFLYIAYSDESVYG--------- -----------------------------------------IRRNEKIAVHCTVRGAKAE EILERGLKVREYELRKGNFSDTGNFGFGIQEHIDLGIKYDPSIGIYGMDFYVVLARPGFR VAYRRKKHNKVGIKHRVRKEEAMKWFQQKYDGVILPGKMGLKFLEFVRPFCAVIPEIAKP ERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSSDPFYWLRVILASNRGTLMELGIS PIVTSSLIMQLLAGAKIIEVGDTPKDRALFNGSQKLFGMVITIGQAIVYVMTGMYGEPAE IGAGVCLLIVLQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVN TGRGTEFEGAVIALFHLLATRQDKVRGLREAFYRQNLPNLMNLMATVFVFGVVIYFQGFR VDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYLISQMLAAKFSGNFFINLLG VWADVGGGGPARSYPVGGLCYYLSPPETLGHVGEDPIHAILYIFFMLGSCAFFSKTWIDV SGSSAKDVAKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIG SGTGILLAVTIIYQYFEIFVKEQSEMGGMSTLLF-------------------------- ------------------------------------GVITKLKMQRTVVVRRDYLHYAKK YNRFEKRHKNISAHISPAFRDVTPGDVATIGECRPLSKTIRFNVVKITKGSGARKGFSKF XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XAKRTKKVGIVGKYGTRYGASLRKLIKKMEVTQHGKYTCSFCGKENMKRRAVGIWHCKSC KKVIAGGAYVYSTTAAATVR-----------MGRRPARCYRYCKNKPYPKSRFCRGVPDS KIRIFDLGRKKARVDDFSLCIHLVSDEYEQLSSEALEAGRICANKYLVKICGKDAFHLRV RVHPFHINRINKMLSCAGADRLQTGMRGAFGKPQGTVARVRIGQPIMSVRGREGDRAHII EALRRAKFKFPGRQKIQMSRKWGFTKWDKTEFEEMRADGRLVPDGVGVQYRPCHGPLQRW ----RVTKVLGRTGSQGQCTQVRVEFLDDSNRSIIRNVKGPVREGDILTLLESEREARRL RXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMVDDRAAAKELDQWIEQLNECKQLTENQVK TLCEKAKEILTKESNVQDVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDR GYYSVETVSLLVSLKVRFKERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDSQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHSNSLTLITRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRC GNQAAIMELDDALKYSFLQFDPAPRRGEPHVTRRTPDYFLMGAYKYMQELYRKKQCDVMR FLLRVRCWQYRQLSSIHRASRPTRPDKARRLGYRAKQGYCIYRIRVRRGGRKRPVPKGAT YGKPTNQGVNQLKFQRSLQSVAEERVGRRCGGLRVLNSYWVAEDSTYKYFEVIMVDTFHK AIRHDAKVNWICKSVHKHREMRGLTSAGKKSRGLGKGHSFHHTIGGSRRACWKRNTMLSI RRKRGIAVGRLGEERKAWRKDHPFGFVARPVKNPDGTLNLMNWECAIPGKKGTAWEGGLY KLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSLLDEEKDWRPAVTIKQILLGIQE LLNEPNIKDPAQAEAYTIYCQNRAEYEKRVRTQAEKYRDPT-GRTSKMIQHVNYRMRCSL QDGRTFIGTFKAFDKHMNLILGDCDEFRKVRPKNSKAREEKRVLGLVLLRGENLVSMTVE GPPPAEDGMSRVPLPGQ-HGPGMGRAAGRGIT-GGGLQGPVRGVGGPSYQNMQPQ--MGR GGPPQEPLTFKLVLVGDGGVGKTTFVKRHLTGEFEKKYVATLGVEVHPLIFHTNRGPIRY NVWDTAGQEKFGGLRDGYYIQGQCAIIMFDVTARVTYKNVPNWHRDLVRVCENIPIVLCG NKVDIKDRKVKAKAIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVEMPA LLPPEIQMDPSLVKQYEQELENAQQVALPDEDDDLNDGIKQYYVSKIEEIQLVVTEKTQN LRRLEAQRNELNAKVRMLREELQLLQEQGSYVGEVVKPMDKKKVLVKVHPEGKFVVDLDK NIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEI KEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ KFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRLESGSGGDSEVQRTMLELLNQLD GFEPKQNIKVIMATNRIDILDSALLRPGRIDRKIEFPAPNEEARLDILKIHSRKMNLTRG INLRKIAEMMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFELAVAKIMLKDSEKNMSI KKQWK------------------------------------------------------- ---------------------------------------------------------SGG AAGAMSLFFVYSLDYCRTRLANDAKSAGKREFNGIIDVYRKTLKSDGVQGLYRGFVISCV GIIVYRGCYFGFYDSLKPILLGEDAGLLASFALGYVVTISSGLVSYPIDTIRRRMMMTSG QAVKYKGSIDCTMQILKNEGFMSLMKGAGANILRGVAGAGVLAGFDKFKALYVRWRLMSD CSDLDRQIEQLRRCEIIKEAEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLK ELFRVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQV YGFYDECLRKYGSITVWRYCTEIFDYLSLSAIIDGKVFCVHGGLSPSIQTLDQIRAIDKK KKVPHDGPMCDLLWSDPEDTNGWGVSPRGAGYLFGSDVVAQFNAANDIDLICRAHQLVME GYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQRDFTIFEAAPQESRGKPQADYFL VRLPPEVNRILYIRNLPYKITAEEMYDIFGKYGAIRQIRVGTTPETKGTAFVVYEDIFDA KNACDHLSGFNVCNRYLVVLYYQSNKAFKKIDQEKKREEIDKMKQKYGLSTPE--XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXX-MRGPKKHLKRLNAPKHWMLDKLGGVFAPRPSTGPHKLRECLPLMVFLRN RLKYALTYDECKKILFQRLIKVDGKVRTDKTYPAGYMDVITIEKTAENFRLIYDVKGRFS VHRITPEEAKYKLCKVKRVSVAPKGVPFIVTHDGRTIRYPDPLVKVNDTVRV-------- ------------------------------------------------------------ ------AITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADNNIVIMLVGNKSDL RHLRAVPTDEAKAFAEKNTLSFIETSALDSTNVETAFQNILTEIYKIVSQKTIRDSPDDN NVQTIHVAPTDNSAERKRSCCNMSSRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVR GKDVVVLGVEKKAVAKLQEDRTVRKIALLDDHVAMAFAGLTADARILINRARVECQSHKL TVEDPVTLEYITRHIATLKQKYTQSNGRRPFGLSTLLIGFDGTPGLYQTDPSGTYHAWKA NAIGRSAKTVREFLEKDYSEETVSEKETIKLAIKALLEVVQTGSKNIELAVMRRNEPLKM LDNEEIEKYITEIEKQKEEEAEKKKQK-------------KKRKYEPPIPTRVGKRKKKI KGPEAANKLPQVTPHTRCRLKMLKLERIKDYLLLEEEFIKNQERLKPQEEKQEEERSKVD DLRGTPMSVGSLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDSLEPGCSVLLNHKVHAVV GVLSDDTDPMVTVMKLDKAPQETYADIGGLDQQIQEIKESVELPLTHPEYYEEMGIKPPK GVILHGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPS IVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSKGDVKVVMATNRIETLDPA LIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTLADDVNVEEYVMAKDDLSGADIKAICT EAGLLALRERRMKVKNEDFKMAKENVLYRKNEGTPEGLYLKRKPYSPFQTSSNAEYVLAR VDDLLNWARRTSLWPLTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQADVIIVAGTL TNKMAPALRKVYDQMPEPRWVVSMGSCANGGGYYHYAYSVVRGCDRIIPVDIYVPGCPPS AEALLYGILQLQRKVKRMNVVQMWYRK-DFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYA NNSNYKNDTMIRKEAFVHKSVMEELKRVIEDSEIMQEDDNIWPNPDRVGRQELEIVIGDE HISFTTSKIGSLVDVNQSKDPEGLRTFYYLVQDLKCLVFSLIGLHFKIKPI--------- ---------ALVMKSGKYVLGYKQTLKTLRQGKGKLVIIANNTPPLRKSEIEYYAMLAKT GVHHYNGNNIELGTACGKYFRVTTLSITDPGDSDIIRSMPSEMTEYKLVVVGAGGVGKSA LTIQLIQNHFVEEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGF L--------------XXYREQIKRVKDADEVPMVLVGNKVDLPTRQVDQKPAKALAESYQ IPYIETSAKTRQGVDDAFYTLVRE----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMKLNISYPATGCQKLIEVDDERKIRSFYEKRIAAEVSAECLGDEWKGYVVRITGGND KQGFPMMQGVLTTGRVRLLLSKNHSCYRPRRNGERKRKSVRGCIVDSNLSVLNMMIVKKG EQDVPGLTDKTIPRRLGPKRASRIRKLFNLTKEDDVRQYVVRRPLPAQTKAPKIQRLVTP LVIQRKRHRIALKRRRASKKREDASEYAKLLAQRMKEAKERKQERRRSASQSKXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXENDELPTVTNKV YFDVKFGDSPENRIVFGLFGDIVPKTVDNFVGLATNK-GYKDSQFHRVIKDFMIQAGDFE NHDGKGTKSIYFPDENFVLKHYGPGWLCMANAGKDTNGSQFYITTVVTSWLDGVHVCFGK VLEGMK------------------------------------------KKKKVVLKFTVD CTHPVEDGIMDSANFEKFLHERIKVNGKTNNLKSKVIIQSDIPFSKRYLKYLTKKYLKKN NLRDWLRVVANTKDSYELRYFQINNEEEEEDD----DEK--EEEKYGGCEGPDAMFVKLV SSDGHEFIVKRDHALTSGTIKAMLSGPGQFAENETNEINFREIPSHVLQKVCMYFSYKVR YTNSSTEIPEFPIAPEIALELLMAANFLDC--------------AKSCWMAIHDKVYDVT KFLEEHPGGEEVLLEQAGKFGTESFEDVGHSTDARELMENYLIGELAEDDRSSLTTWLIP LGIVIAAALVYRFIMSYMLQHLHNGWQVDQAILSEEDRVVVIRFGHDWDPTCMVMDETLY RCAEKVKNFCVVYLVDITEVPDFNKMYELYDPCTSMFFYRNKHIMIDLGTGNNNKINWCM EDEQEFTDIVETVFRGARKGRGLVVSPKDYSTKYRYKRLQRQLEFLEVQEEYIKDEQKNL KKEYLHAQEEVKRIQSVPLVIGQFLEAVDQNTGIVGSTTGSNYYVRILSTIDRELLKPSA SVALHKHSNALVDVLPPEADSSITMLQADEKPEVSYADIGGMDIQKQEVREAVELPLTHF DLYKQIGIDPPRGVLMFGPPGCGKTMLAKAVAHHTTASFIRVVGSEFVQKYLGEGPRMVR DVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTVNVKVI MATNRADTLDPALLRPGRLDRKIEFPIPDRRQKRLIFSTITSNMNLSEEVDLEDYVARPD RITGADINAICQEAGMQAVRENRYVVLAKDFEKGYKNNIKKDETEHEFYKSTAPLTMELI RERVLLVLKLYDKIDPEKLTLDSHFMNDLGLDSLDTVEVIMAMEDEFGFEIPDADAERLL KPADVIQYIADK---SRRV--LSDDLKNVEFETSEEVEVTPTFDSMGLREDLIRGIYAYG FEKPSAIQQRSIKPIVKGRDVIAQAQSGTGKTATFSISILQGLDTQMRETQALILSPTRE LATQIQKVILALGDYMSVQCHSCIGGTNIGEDIRKLDYGQHVVSGTPGRVFDMIRRRNLR TRAIKMLILDEADEMLNKGFKEQIYDVYRYLPPATQVILISATLPHEILEITSKFMTDPI RILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKM REANFTVSSMHGDMPQKEREAIMKEFRSGASRVLITTDVWARGLDVQQVSLVINYDLPNN RELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLIMALRRP FDPVAHELEQNFRLTKFADLKGGCKVPQDVLLKLLEGL-QAQDSEQSHFQYVAAVPRIGI GMDCCVTPLRHGGLSLVQTTDFFYPLVDDPYMMGKIACANVLSDLYALGVTECDNMLSLL AVSTKMTDKERDVVMPLMLRGFRDLAEEAGTSVNGGQTVMNPWLTVGGVATTVCQPNEFI TPDNAVVGDVLVMTKPLGTQVAVNAYSWLDQPERWNRIKLVVSEDDTRKAYQRAMFSMAR LNRTAARLMHKYNAHGATDVTGFGLLGHANNLARIQKNEVGFVIHNLPVIAKMASVAKAC GQMFGLLQGVSAETSGGLLISLPREQAAAFCKDIEKQEGYQAWIVGIVEKGTRTAR---- ---------------------------IDAHAEECFFDKVSSGTKMSLMFEVAEGGFLDI DVTIIGPDGKSIYSGDRESNGKYTFAAHMDGVYKYCFSNKMSTMTPKIVMFTMDLGEKPK AHHNKLEDM--------------------------------------------------- ------------------------------------------------------------ ---------------------GSVNSLRISIVIKQADEIEKILCHKFMRFMMMRAENFVV LRRKPVEGYDISFLITNFHTEQMYKHKLVDFIIHFMEEIDKEISDIKLAVNSRARISAEE FLKMF-------------------------------------------LTKEVMVDDRLV TMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTMPNTFKTLDSWRDEFLIQASPRDPEN FPFVVIGNKIDMEKR--------------------------------------------- --------------------------TAPFDARFPNQNQTRNCWQNFVDFYRCQKIEDHA PCDYFKMCYTAMCPDEWIEQWTDQIESKSFAGKIMPDYLGTDQRKVKDDDTKDKPIQSLD EGDIALLKTYGAGMYSRSIKGVEDDIQNVLKRVNELSGIKESDTGLAPPALWDLAADKQT LQSEQPLQVARCTKIINADSDDPKYIINVKQFAKFVVDLGDQVAPTDIEEGMRVGVDRNK YQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIDKLREVVEVPLLHPERFVNLGI EPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMART KKACIIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDT LDPALMRPGRLDRKVEFGLPDLEGRSHIFKIHARSMSVEKDIRYELLARLCPNSTGADIR SVCTEAGMFAIRARRKMATEKDFLEAVNKVIKAYAKFSSTPRYMTYN------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------KPLRLPLQDVYKIGGIGTVP VGRVETGILKAGMVVTFAPANLTTEVKSVEMHHCTLEKAEPGDNVGFNVKNVSVKDIRRG NVAGDSKHDPPKEAANFDAQVIILNHPGSIVKGYTPVLDCHTAHIACKFFELKEKIDRRS GKKLEDNPEKLKSGDSAIVTMVPSKPMCVEAFSEYQPLGRFAVRDMRQTVAVGVIKKVEK KD-ATSKMTKAAQKAELEQLRQESEQLKNQIREARKAAADTTLGQVASQVEPVGRIQMRT RRTL----------------------------------------------XXVMTCAYAP SGSYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIVTSSGDMTCA LWDIETGQQTTSFTGHTGDVMSLSLSPDMKTFVSGACDASAKLWDIRDGMCKQTFSGHES DINAITFFPNGHAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLG GYDDFNCNVWDTLRQERAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKIWN------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------AANVEEAFINTAKEIYQKIQDGVFDINNEANGIKI GPQHSSTNPSGGGSGNQGGG--RGRTELGDVTVHNIKQLKRLNQVVFPVTYNDKFYKDVL EVGELAKLAYFNDIVVGAVCCREDKSDNQRRLYIMTLGCLAPYRRYGIGSIMVQHVLKIC EDDGNFDNIYLHIQINNEGGI-----------------------------------XXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMSKVSRDTLYEAVNAILQKKRKFTESVELQISLKNYDPQKDKRFSGTVKLRSIPR-- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------MSDADKLNIDSIIARLLEVRGSRPG KNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLTSGRPVTPPRGSAKNK GKMMFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEIVGTNVSTT YITCPADAKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVKRRFRASNYQSTTRVKPF ICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETHRVQIHANCRIRRVYFSDRLYSEDEL PAEFKLYLPVQGKM--TDITNLSDPFADAEGIHIRIQQRNGRKTLTTVQGISSEYDLKRI VKFCKKEYACNGTVVDHSEYGEVIQLQGDQRNNVATMLVKGGMQDQVKVHGF--VYSFDG LLVFALLVICTCAYVKRV-PRLVLSEKKGFMGIFYKAAVIGTRLHIPVAISCIAMGIYVL LL-SSRITSALARHLPRAVAKKNALGAGFVACRNVSTTAEVSSILEERILGTSKANLEET GRVLSIGDGIARVYGLKNIQAEEMVEFSSGLKGMALNLEPDNVGIVVFGNDKLIKEGDTV KRTGAIVDVPVGEEILGRVVDALGNPIDGKGPLGVATRARVGVKAPGIIPRISVKEPMQT GIKAVDSLVPIGRGQRELIIGDRQTGKTAIAIDTIINQKRFNDAADEKLKLYCVYVAIGQ KRSTVAQIVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCAMGEYFRDNGKHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDDFGGGSLTALPVIE TQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTKAMKQVAG SMKLELAQYREVAAFAQFGSDLDQATQNLLNRGVRLTELLKQGQYVPMAIEEQVVILYAG VRGYLDKIDPSKITTFEKEFTKHILSSQQDVLKTIREENAISPETDEKLKGIVKNFLAGF MEVFYRIPYTVLECPNIKLKRPSWVKQPSAMVMFGIVLASYFLVTGGIIYDVIVEPPSIG STTDERGNTKPVAFMPYRVNGQYIMEGLASSFLFTLGGLGFIILDQTNKPTTPKLNRILL LSVGFVCILVSFFTCRVFMRMKLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEYAQVTKMLGNG RLEAMCFDGTKRLCHIRGKLRKKVWINASDIILIGLRDYQDAKADVILKYTPDEARNLKA YGELPESAKINEDQDDNITFEEIDEIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-SMNK PKSELTPEELAMREQEEFNTGPLSVLTQSVKNNTQVLINCRNNKKLLGRVKAFDRHCNMV LENVKEMWSEVPKTGKGKKK---------------------------------------- -------------------RCEGINISGSFYRNKLKYLDFLKKRMNTNPSRGPYHFRAPS KVFWRTVRGMLPHKLARGKQAMDRLKVFEGIPPPYDKQKRMGVPSALKDLRVKPR----- ------------------------------------------------------------ GDVDKGKKIFVQRCAQCHTVEKSGKHKTGPNLNGLFGRSTGQAAGFSYTEANKKKGITWG RDTLFVYLENPKKYIPGTKMIFAGLKKKTDREHLIAYLEDSTKIFVERTLAIIKPDAVTE EIEDIILRSGFTILQKRRVHLTPEQASDFYVEHYGKLFFPSLVAYMSGGPIVALVLSREK AISYWRELIGPTNTLKARQTHPDCLRAVYGTDDQMNALHGSDSFSGAAREIRFFFPESVV EPVPVGQAARDYLAHSVNPTLLKGLTELCKMKP----------------------MFEAR LVQGSLLKKVLDSIKDLLTDGSWDCSSTGMSLQAMDSSHVSLVSLMLRCDGFDTYRCDRN MTMGINLGSMSKILRCAGNDDAITIKAGDNADTVTFMFESPNQEKVSDYEVKLMDIDTEH LGIPETDYSCVVKMPASEFQRICRDLSQIGESVVICCTKEGVKFSASGDLGTGNVKLAQT ANVDKEEEAVTIEMQEAVTLTFALRYLNFFTKATPLSPQVTLSMSPDVPLVVEYKFADMG YVRYYLAPKIEDNEDG-----------------------------------ILNALEVTN RSPRLVLEVSQHLGENTVRTIAMDGTEGLVRGNECVDVGTAIRIPVGRETLGRIINVIGE PIDERGPVKSQAHLAIHQEAPDFVDMSVEQEILETGIKVVDLLAPYSKGGKIGLFGGAGV GKTVLIMELINNIAKAHGGYSVFAGVGERTREGNDLYHEMIATGVIDLKGDNSKVSLVYG QMNEPPGARARVCLTGLTVAEYFRDAEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIA ELGIYPAVDPLDSTSRILDPNVVGSEHYNIARGVQKILQDHKSLQDIIAILGMDELSEED KLTVTRARKIQKFLSQPFQMAEVFTGKTGRFVPLKETIRGFAEILEGKWDHLPEVAFYMV GPIEEVAEKAEALAEEQMLMPKKNRVAIYENLFKEGVMVAKKDFYAPRHPELDVPNLQVI KALQSLKSRGYVNEQFAWRHYYWYLTNEGIQYLRDFLHLPPEIVPSTLKRQSMGADRAEY RRGGGSDKKGDVGAGATMGKKNSKLKHEDIEELQRRTGFSENELVQWHKGFMKDCPTGTL SLESFLKIYKQFFPYGDPSRFASLVFKKFDENKDGEVEFKEFIYALAVTSRGNMEQKLEW AFQLYDLDEDGYVTRKEMLDIVGAVYQMLGNHVKMSEDENTPEKRVDRIFDTMDKNHDDK LSLEEFREGSKKDPTIVHAL-----SSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNL TGLNEQVPHYRQALDMILDLEPDDELEDNPNTSDLIEQAAEMLYGLIHARYIMTNRGIAQ MIDKWQQGDFCYCPRVYCENQPMLPI---------------------------------- ------------------------------------------------------------ MTNTKGYRRGTRYMFSRKFRTKGQIKLSQYMITYKRGDIVDIKGNGAVQKGMPYKAYHGR TGRIFNVTQHAVGVIVNKRVCGKILPKRLNVRIEHIKHSNCRLDFLNRVKKNEVLKKEAK AYVDVKRKPQQPRPAQLIRTKYNK-------------PCRSNYKNVSPEEGEMDVSSMTD RVASHIFFAELVKGFSVVGGTIFKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAICPAQAITIDAETREDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEY STETHEELLYNKEKLLENGDKWEAE------------MASPAKVAKPETKNNHENDKEQQ EAIEQIDEVQNEIDRLNENASEEILKVEQKYNKLRQPHFQKRSELIAKIPNFWVTAFVNH PQVSALLNEEDEEALQFLTKVEVQEFEDIKSGYRIKFHFDTNPYFENTSISKEFHLNSSK STSITWKAGKDLTKKSKKRSHEEQESFFGWFTDHGDAGADELGEVIKDDIWPNPLQYYLA SEIEDEGADEEGIDDEEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXX---------KVCLLGESGVGKSSLMQRFVHDNFRHNTDSTIGASFMTKN LEVNGVTYKFQIWDTAGQEKYRSLAPMYYRGAAAAVIVYDVTSESSFKTLKMWMSELQRH GPPNIVIAIAGNKTDLREVGTSDAAHYAEKMCAIFLETSAKTARNVGEIFVEISQKLPVE D------------------------------------RHGERCSRLHNKPTFSQTMLMQN LYLNPQNTAQVQVTDVEVQQHYDEFFEEIFVELQTKYGEIEEMNVCDNLGDHLVGNVYVK FRYEEDAEKAVNDLNTRWFNSRPIHSELSPVTDFREACCRQYEMGECTRGGFCNFMHLKP ISRELRRELYGHNRKSRSRSPPTRRSRSPNPNRERRRSRSPRRRSMFLTRSEYDRGVNTF SPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVVLAVEKRVTSPLIEPSSIEKIMEVDNHIG CAMSGLIADSRTMIDRARVEAQNHWFTYNEKMSVESVTQAVSNLALQFGDDDADPGAMSR PFGVALLFAGIDTKGPQLFHMDPSGTFIQYDAKAIGSGSEGAQQALQEVYHKAMTLKEAC KHALTILKQVMEEKLNSTNVEMAKVTPEKMFHMFTKEELEDVIKEI-------------- --------------------KPWEKDPHYFKYIKISALALLKMVMHARSGGNLEVMGLML GKVDGNTMIVMDSFALPVEGTETRVNAQAQAYEYMAAYTESAKQVGRLENAIGWYH---- ------------------------------------------------------------ ----------NFGVHCKQYYSLEVSYFKSSFDRKLLESLWNKYWVNTLSSSSLITNADYM TGQIFDLADKLEQSETQLGRGGFMEKKSEDKLAKATKDGCKNTIEALHGLMSQVIKDKLF NQV---------ETQRLANEPVPGIEALPDESNARYFHVVVKGPADSPYEGGTFKLELFL PEEYPMSAPKVRFMTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPD DPLANDVAEQWKVNEAQAIETARAWTRLYA---EELLDYE-EDEHETKDVKGTYVSIHSS GFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILSMDVLCQAKSGMGKTAVFVLATLQ QLEPVDGQVSVLVTCHTRELAFQISREYERFSKYMNSVKIAVFFGGVSVKKDEDVLKKNC PHIVVGTPGRLLALIKVLSLKHIKHFILDECDKVLEQLDMRRDVQDIFRMTPHEKQVMMF SATLSKEIRPVCKKFMQDPMEVYVDDDSKLTLHGLQQHYVKLKDNEKNRKLFELLDVLEF NQVIIFVRTVQRCMALAQLLVEQNFPAIAIHRAMPQEERLQRYQQFKDFQKRILVATNLF GRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKVPPCYGDLG KSARDLFSKGYNYGFYKLECKTKTSTGVNFTTSGSQNQDTSKSAGTLETKYKLDDYGLTF TEKWNTENILGTEITIEDQIAKGLKLTFDTSFAPTTGKKSGKIKTAYKREYLNLNCDVDF DFAGPTIHGAAVLGYNGWLGGYQMSFDKSKLAKSNFAVGYTADDFTLHTNVNDGAEFGGS IYQRVNSELETGVNLSWTAGTNATRFALGAKYTPDRDTTLRAKINNSSQIGLSYQQKLRD GVTLTLSSLVEGKNFNQGGHKIGLGFDLE-DSVREKALTDYRKKLLEHKELEARLKEMRE QLKELTKQYDKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKAK LRAGTRVALDMTTLTIMRYLPREVDPLVYNMSMEDPGDISYSQVGGLGDQIRELREVIEL PLLNPELFQRVGITPPKGCLLFGPPGTGKTLLARAVSSQLDANFLKVVSSAIVDKYIGES ARLIREMFGYARDHQPCIIFMDEIDAIRRFSEGTSADREIQRTLMELLNQMDGFEALGQV KMIMATNRPDTLDPALLRPGRLDRKIEIPLPNEQARMDIMKIHAAPIAKHGEIDWEAVVK LSDDFNGADLRNVCTEAGMFAIRAERDYVIEEDFMKAVRKVADNKKLESKLDYKPLXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------QLLPL ELVDKCIGSRIHIIMKNDKEIVGILMGFDDFVNMVLEDVTEFESTPEGRRVTKLDKILLN GNNITMLVPGGEGPEVIDHYENPRNVGSLDKGDKTVGTGLVGAPACGDVMKLQIKVDENG KIVDAKFKTFGCGSAIASSSLATEWVKGKSLDEASTIKNTQIAQELSLPPVKLHCSMLAE DAIRAALSDYKKKN-MLVLVLGDLHIPHRCNSVPGKFKKLLVPGKIQHILCTGNLCTKES FDYLKTLASDVHVVRGDFDENLNYPEQKVVTVGQFRIGLCHGHQVVPWGDTESLAMLQRQ LDVDILITGHTHKFEAFEHENKFYINPGSATGAYNPLDS-ITPSFVLLDIQQSTVVAYVY QLLGDDVKVERIEYKKMGKFMKSGKVVLVLGGRYAGRKAVIVKNYDDGTQDKQYSHALVA GIDRYPRKVTKKMGKKKIKQRSKVKAFIKVYNYNHLMPTRYSIVPLDKQLVNKDAFRDPA LRRKAKRDAKAKFEERYKTGKNKWFFQKLKFERTFIMVKPDGVQRGLVGETIKRFEQRGY KLVAMKMMQASEDHLKKHYADLASKAFFPGLVKYMSSGPVVPMVWEG------------- ----------------------------------------------------------DP APKPVKTVGKAKEKALKAKKHVLRGVHGKRQRKVRTSVHFYKPKTLRLPRRPRYPRKSTP RRNRLDQFKIVKFPLTTESAMKKIEDNNTLVFIVDKRSNKPQIKLAVKQLYDIDVSKVNT LIRPDGEKKAYVRLAPDYDALDVANKIGII---------ANEKHSKNILTRGNVPKTLKP SEDKYPVGPWLLALFIFVVCGSAVFQIIQSIRFXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX--TVFGKILRGEIPCKFIYEDEKVVAFDDLNPQAPVHFLLIPR KAIPKLSGDTELLGHMMVVASKVASQKDGYRLVVNNGRHGGQSVYHLHMHVLGGRQLGWP PMGGLFSYFSGLFGTKERRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVAYKN LKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSMDRDRIGISKQELVSMLEEDELKKAI LVVFANKQDIEGAMTVTEVANALGLSSMKNRKYQIFKTSAIKGEGLDEAMEWLANTITQA KXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXMFYHVSLEHEILLHPRYFGPNLLNTVKQKLFTEVEGTCTGKY GFVIAVTTIDNIGAGIIQPSRGFVLYPVKYKAIVFRPFKGEVLDAVVTQVNKVGLFTEIG PLSCFISRHXI------------------------------------------------- ----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMAKKTY DLLFKLLLIGDSGVGKTCLLFRFSDDAFNTTFISTIGIDFKIKTVELGGKKIKLQIWDTA GQERYRAITSAY------------------------------------------------ -----------------------------------------------MPQNEHIELHRKR HGYRLDYHERKRKKEGRMAHEASQKAKKLRGLKAKLYNKKRHSEKVQMKKTLKMHEEKKT KQKSNEDVPEGAVPAYLLDREGQSRAKVLSNMIKQKRKEKAGKWDVPLPKVRGVSEAEVF KVVKTGKTRRKAWKRMVTKACYVGEGFTRKPPKYERFIRPMALRFKKAHVTHPELKATFC LPIIGVKKNPSSPMYTALGVITKGTVIEVNISELGLVTQAGKVIWGKYAQVTNNPENDGC INAVLLVMAARPLISVYNEKGESTDSNVTLPAVFRAPIRPDIVTFVHSEMRKNTRQPYAV SKKAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRR INVNQKRYAICSAIAATGIPALVMSKGHRIEQIPEVPLVLSDKVEEYKKTKEAVGLLKHL KAWSDIEKVYKSKRFRAGKGKMRNRRRIMRRGPLVIYNQDNGICRAFRNIPGVTLINVAH LNLLKIAPGGHVGRFCLWTESAFKKLDSIYGTWRKSSKEKTNYNLPMPKMTNSDLTRLLR SEEIQKALRAPKTDIQKKVLKRNPLKNTRAMLRLNPFDAVAKRTSKRKADRQKAADQRRG IVTVDTGVKPRPR----GSGEQELATKTLQIQSKRFYLDVKQNRRGRFIKIAEVGSGGKK SRLLLAMSTAAEFRDNLTEFSEHYASLGPPNPDNVPEDGKLKSEVMVKDNRRYYLDLKEN QRGRFLRVSPRSQQRSQIAIPAQGMIEFRDALTDLLDEFGTDDHESQGELPEPRSMRVEN KMFYFDVGQNRRGVFMRISESNFRTAVTIPERSWTRFRDVLSDFVDK------------- ---------------------------------HTVKVVKQKGLEHITVDDLVSEITPRG RALVPDQVKKELLQRIRTFLAQQSNMNIRCAKPEDLMNMQHCNLLCLPENYQMKYYFYHG LSWPQLSYVAEDEKGKIVGYVLAKMEEDPED-VPHGHITSLAVKRSHRRLGLAQKLMDQA SQAMVEAFKARYVSLHVRKSNRAALHLYASTLKFEINETEPKYYADGEDAYAMKRDLT-- ----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSEQTEEKKVEEPKR -VHTYPLIRHSDMNEEMRTEAMELCVTACEKFSSNNENAAKLIKETMDKKFGASWHVVVG EGFGFEITHEVKNLLYMFFGGNMAITVWKCS----------------------------- ------------------------------------------------------------ ------------FRTLFAQHLSEECRRRFYKNWYRSKKKAFTKYSKKWQDDQGKKEIEKD FAKMKKYCKVIRIIAHTQMKLMKKRQKKAHIMEIQVNGGTIAQKVDWAREHLEKQVPVTD IFDKDEMXDTIGVTKGKGFKGVTSRWHTKKLPRKTHKGLRKVACIGAWHPSRVGFSIARA GQKGYHHRTEINKKIYRIGQGIHTKDGKVIKNNASTDYDLTEKTITPMGGFPHYGECNND FIMILGCCVGPKKRVVTLRKSLLVHTKRKAMEKIKIKFIDTSSKFGHGRFQTPQEKQNFM GPLKKD--------------------ISYTTNSFPSDYVPTVFDNYSANIMVDGKPINLG LWDTAGQEDYDRLRPLSYPQTDVFFVCYCVERRSSFENIEPKWIPEICHHCPDAHIILVA CKIDLR------------------------------------------------------ ------------------------------------------------------------ ------------------KKKKSNTDRDYTYDELLNRVFDIMREKNPDMVAGEKKRFVMK PPQVMRVGTKKSSFSNFAEICKI------------------------------------- ------------------------------------------------------------ --------FEDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGK DYSLHRLILGTHTSDEQNHLLIASVQLPNDNAQFDASHYDSEKGEFGGFGSVSGKIEIEI KINHEGEVNRARYMPQNPCVLATKTPSSDVLVFDYTKHPSKPDPSGECQPELRLKGHQKE GYGLSWNPNLNGNLLSASDDHTICLWDINTTPREGRCIDAHTIFTGHTSVVEDVSWHLLH ESLFGSVADDQKLMIWDTRSNNTSKPSHTVDAHTAEVNCLSFNPYSEFILATGSADKTVA LWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQSAEDA EDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEEPDTPAS ELEMPAPSRARVYADVNTHRPRDYWDYESHAVEWGQQDDYQIVRKLGRGKYSEVFEAVNI TNNDKCVIKILKPVKKKKIKREIKILENLRGGTNIISLVAIVKDPVSRTPALIFEHVNNT DFKQLYQTLTDYDIRFYLFELLKALDFCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLA EFYHPGQEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPFFHGHDNY DQLVRIAKVLGTEELYEYIDKYQIELDPRFNEILGRHSRKRWERFVHSENQHLVSPEALD FLDKLLRYDHAERLTAREAMDHPYF------RVPESLLKKRKQNAEKNREKRRVMFKRAE KYVKEYRIKERDEIRLAREARKTNNFYVPGEPKLAFVTRIRGINGIHPRPRKIMKLFRLL QINNGTFVKLNKATLSMLRIADPYITWGYPNLKSVKELVYKRGYGKIEGKRIPLTDNALI EKKLGQYGIICMEDLVHEICTVGPHFKQANNFLWTFKLNTPNGGWRIKNNHFVDGGDFGN REDKINSLLKRMMQFMLLFSRQGKLRLQKWYVPHADRLKKKITRELITTILSRKPKMCSF LEWRDLKIVYKRYASLYFCCAIEQDDNELLTLEIIHRYVELLDKYFGSVCELDIIFNFEK AYFMLDELLLGGEVQETSKKNVLKAIAAQDLLQEETPQGFFEDHGLGMSKAHPPELKKYM DKKLSLKLNGSRTVTGILRGFDPFMNLVVDEAIEETKSGEKNSIGMVVVRGNSIVLLESL DRIEFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTI RLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFQQTSKWIDDVRTERGSDVIIM LVGNKTDLSDKRQVS--------------------------------------------- -----------------MAIRYDLAVGVNKGHKVTVRKPRPSRRKGQLNKHVKFIRDIVR EISGFAPYERRAMELLRISKDKRALKFCKKRLGSHIRGKRKREEMQKVLQAQRKAXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------DDVRRMNKRQLYYQ FLNFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNYRDEPIRVGE IVVFKIEGREIPIVHRVLKVHEK------------------------------------- ------------------------------------------------LFKLLLIGDSGV GKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYR GAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEY ADQLGIPFLETSAKNATNVEQAFMTMAAEIKNRMGPVSTTPNVKINASTPVKQSGGGCC- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------KGVLLYGAPGTGKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGA KLVRDAFALAKEKSPAIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNSN IKVIAATNRVDILDPALLRSGRLDRKIEFPTPNEEARARIMQIHSRKMNVSTEVNYEELA RCTDDFNGAMCKAVCVEAGMIALRRGATELSHEDYMDAIMEVQAKKKTNLQYYA------ ----------------------------------------------------------WD TAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDNAQVVLVGNKC DLEDERVVSFDRGKQLADQLGLEFFETSAKENIHVKAVFERLVDIICDKMSESLDSD--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------DHEDNFAIVFAAMGVNMEIARFFKQDFE ENGSMENVCLFLNLANDPTIERIITPRIALTTAEFMAYQCEKHVLVILTDMSSYAEALRE VSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLT GYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRDDHADVSNQLYACYAIG KDVQAMKAVVGEEALTPEDMLYLEFLQKFEKNFIAQSHYENRTIFETLDIGWQLLRIFPK EMLKRIPAEKLAKYYPRDS--------------------KEDKENRVLLYACRNCDYQQE ADNQCIYVNKITHEVDELTQIVADVIADPTLPRTEDHPCPECQHKEAVFFQSQTTR---- ----------------------------------------------------------PL KGARITGCLHMTVQTAVLIETLLELGAKVQWSSCNIFSTQDHAAAAMAKRGVAVYAWKGE TDEEYIW--------------------------------------------XTTTGVHNL YKMMSKGLLKVPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGKVAVVGGYGDV GKGCATALRAFGSRVIVTEIDPINALQAAMEGYEVSTMDEACKEARIFVTTTGCKDIICS RHFEQMQEDSIVCNIGHFDCELDVAWLNDNCKHKENIKPQVDRYTLKNGRHIILLAEGRL VNLGCAMGHPSFVMSNSFTNQVLAQIELWTKTDQYKVGVHILPKKLDEEVAAAHLEHLGV KLTKLSDDQATYLGIPQEGPFKPDHYRY---------------------SLDERIYVKMR NDRELRGRLHAYDQHLNMVLGEVEETVTTVEIDEETYEEIYKSTKRNIPMLFVRGDGVIL ---------SSNVENLSPQVIRQVAKELSDLASNPPEGIKVFPNEEDITEIQATIEGPSG TPYSGGQFRMKLVLGKNFPAEPPKGFFLTKIFHPNVAKNGEICVNTLKKDWKPVLGIKQV LLTIKCLLIVPNPESALNEEAGKLLLEQYDDYSTRAKIYTEIHAKP-------------- -----------------VEEISCEYGSAKFYALCGFGGILSCGSTHTALVPLDLVKCRIQ VDPVKYGNIINGFRITLREGGVRGLGKGWAPTFFGYSVQGLGKFGLYEVFKSVYSGILGE ENTFLWRTSLYLAASASAEFFADIALCPFEAVKVRIQTMPGFANTLREAWPKIYATEGLT GFYKGLVPLWARQIPYTMMKFACFERTVEALYKFVVPKPRSQCSKPEQLVVTFIAGYIAG IFCAIVSHPADTIVSKLNQDKGSNFVQVAKKLGFRGMWMGLFPRIIMIGTLTALQWFIYD SVKVAFRLPRPPPPEMPESLKQKL-HWKTERVLAVALLGIIPSTFIYAADLVVTGVCLHV FWSLDGVTNDYMHGAALGYASLLYFIFNDVGIGGAAHMLW-------------------- --------------------------------------RFSRFKNRETIAAVRSLLMQKK LHKFELAALANLCPESAEEAKALVPSLEGRFEDDELQSILDDIQTKRSFQY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------GTVAEGAPIIPISAQLKYNIEVICEYIIKKIPIPIRDFTSEPRLIVI RSFDVNKPGCEVDDLKGGVAGGSILRGVLKVGQEIEVRP--------------------- ------------------GVGTKIDPTLCRADRMVGQVLGAVGALPDIYTELEISYFLLR RLLGVRTEGDKKGAKVQKLSKNEILMVNIGSLSSGGRVLA-------------------- -------------------------------------------------TFLIGIIRHYV TILLSSE-KVELTQIADSQILIRSRMLRENGRFIPRQAFLLRKHFFNAEGTGFFMKNPMT DPSMMTDMLKGNITNVLPMIVIGGWINWAFSGFLTTKVPFPLTYRFKPMLQRGVELA--- ------------------------------------------------------------ --------------------MFLWDWFAGILNFLGLYKKSGKLVFLGLDNAGKTTLLHML KDDRMAQHVPTLHPTSEELTMGGMRFTTFDLGGHQQARRVWKDYFPAVDGVVFLIDAFDR ERFVEAKAELDSLLSDEQVANAPVLILGNKIDMPGAGSEDEIRHMFGLHGQSTGKGTVSR SELRPMELFMCSVLKRQGYGEGFRWLAQYIN----------------------------- --------------------------------KYEHLRQFCMELNGLAVKLQMECNPETC TQMTATEQWIFLCAAHKTPKECPAIDYTRHTLDGAACLLN-------------------- ---RRVYRIFSHAYFHHRALFDEYENETFLCRRFTTFVTKYNLMSKDNLIVPILEEQMPN IKLQSSDGEIFDVDVEIAKQSVTIKTMLEDDEDEEEPVPLPNVNAAILKKVIQWCTFHKD DPPPPEDDENKEKRTDDISSWDSEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMI KGKTPEEIRKTFNIKNDFTPAEEEQVRKENEWCEEKXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GNV LRSEIVGAVKMRVYLSGMPELRLGLNDKVLFESTGRGKSKSVELEDVKFHQCVKLSRFDN DRTISFIPPDGEFELMSYRLNTHVKPLIWV------------------------------ ------------------------------------------KEYLMRAHFGLPSVLGED SEGKPPIHVRFEIPYFTVSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRTQMGILEK IEEIESEMARTQKNKATSGHLGLLKARLAKLRRELIEPKGGGGGAGEGFDVAKTGDARIG FVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDG KGRGKQVIAVARTCSLIFIILDVLKPLQHKKLIEHEVEGFGIRLNKEPPNIVFRKK---- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------X XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------- ----ELRKVPVPANRYTPLKENWMKIFTPIVEHLHLQVRFNLKTRNVEIKSCKETKDIGA LQKATDFVKAFTLGFEIEDSLALVRLDDLYLESFEITDVKPLKGDHLARAIGRIAGKGGK TKFTIENVTKXSKV---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------QKQWPLYMSTKNTILKRYDGRFKDIFQEIFESTYQKDFDK AGIWYEHRLIDDMVAQVLKSEGGFVWGCKNYDGDVQSDIVAQGYGSLGLMTSVLLCPDGK TVEAEAAHGTVTRHYREHQKGNPTSTNPIASIFAWTRGLEHRAKLDDNPELARYCQIMEK ACVDTVESGKMTKDLAGCIHGLKNVKPEHYLYTMDFLDAITEEFNXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------- ------------------------------------------------------------ -----DDDDFDPFASEAEKLKQERLTQYAEKKSPGIIAKSSLLLDVKVWDDETDLNEMEK CVRSIVMDGLLWGASKFVPVGYGIKKLQICCVIEDDKVSTDDLEEKITSFEDYIQSMDIA AFNKI-----------------------GLDDALEARNVSQGMVGQMPARRAAGIILEMI KEGKIAGRAILIAGHPGTGKTAIAMGMAQALGQDTPFTSIAGSEIFSLEMSKTESLTQAF RKSIGVRIKEETEIIEGEVVEIQIDRPATGTGAKVGKLTLKTTEMETIYDLGQKMIESLT KEKVQAGDIITIDKATGKITRLGRSFTR-------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------MAEFDLTTRMGQYLDRHLVFPLLEFLSVK EIYDESEMLKGKLDLLSNTNMVDFAMDVHSQLYPDQEVPTSLKDKRRNVVEDLKRLQSQV EPIFKIFEDPEVMIQTSRDGKALFDSLARSHDFRSEMLDTLYQFAKFQYECGNYSGAAEY LYFVRVLVPPGDKNALAALWGKLASEILMQDWDAALEDLNRLREVVDGGLQSLQQRTWLI HWSLFVFFNHPKGRDLIIDMFLYTPQYLNAIQTMCPHILRYLTTAVITNKTVLKDLVKVI QQESYTYRDPITEFLECLYVNFDFNGAQQKLRECETVLVNDFFLVACLDDFIENARLFIF ETFCRIHQCISISMLAEKLNMSPDEAERWIVNLIRNARLDAKIDSKLGHVVMGAQAVSPY QQVIEKTKGLSFRSQMLAINIEKKL----MGVEVETISAGDGQSFPKMGQTAVVHYTGTL TNGTKFDSSRDRGKPFKFKVGKGEVIRGWD------------------------------ -----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXX----------------------------------- --------KFYGDAEKDKGIQTSQDARFYALSAKFE-PFSNEGKTLVIQFTVKHEQNIDC GGGYAKVFGKDLNQKDMHGDSPYYIMFGPDICGPGTKKVHVIFNYKGKNLLTKKDIRCKD DVFTHLYTLIVRPDNTYEVKIDNAKVESGELDADWDFLPAKKIKDPEAKKPDDWDEREKI DDPEDKKPEDWEKPEHIPDPDAKKPEDWDDEMDGEWEPPMIDNPEYKGEWKPKQIDNPAF KGKWVHPEIDNPEYTADSNLYKYDDISHIGFDLWQGKSGTIFDNVLITDDEKFAEQHGKE TWEKTKDGEKKMKDQQDEEERKQKEEEEKTKKEEEDVK---------------------- ------------------------------------AEIIMLEGMTCIYRSNVDLFFYVI GSGQENELILSSVLNAFYDAINQMLRKNVEKRTLLDNLDGVFLALDEICDGGIILEAD-- -----------------------------------------RLIGDLSHLFAIILLLIRI WRTRSCAGLSGKSQIMFAVVFTSRYLDLFTTFVSVYNTTMKSIFILMAFATVYLMYVKFR ATYDSNHDTFRMEFLIVPVGGLAFLVNHEFSPLEILWTFSIYLESVAILPQLFMISKTGE AESIPSH----------------------------------------------------- ---------MKIEEVKSTTKTQRIATHSHIKGLGLDENGYAHQNAAGLVGQELAREAAGV IVDMIKAKKMAGRAVLFAGPPGTGKTAIALAIAQELGSKVPFCPMVGSEVYSSEIKKTEV LMENFRRAIGLRIKETKEVYEGEVTELTPVETENPMGGYGKTVSHVVIGLKTTKGTKQLK LDPSIYESIQKEKVEVGDVIYIESNSGAVKRQGRSDTFATEFDLEAEEYVPLPKGDVHKK KEVIQDVTLHDLDVANARPQGGQDIMSMMGQLMKPKKTEITDKLRKEINKVVNKYIDQGI AELVPGVLFVDEVHMLDIECFTYLHRALESTIAPIVIFATNRGRCTIRGTEDLVSPHGIP LDMLDRLMIIRTLPYSQDEMQQIISIPA-------------------------------- ---------------------------------------------DFQVDEEGDKGLQKL KEKARRRKGRGF-TRSGVHEYEAMEVGGPGPQRSVEGWILFMTNVHEEAQEDDIMDKFAD YGEIKNIHLNLDRRTGFLKGYALVEYETFKEAQSAMEALNGSEILGQKINVDWAFVRGPS QK-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTFMFTSESVGEGHPDKICDQI SDAVLDAHLRLDPNAKVACETCSKTGMIMLLGEISSTAHVDYQKIVRDCVKHIGYDSSDK GFDYKTCNVLVALEEQSPDIAQGVHVDRDESNIGAGDQGLMFGYATDETDECMPLTVVLA HQLNAKIADLRRNGSLSWARPDSKTQVTCEYKIVKGACIPIRVHTVVISVQHSEDITIEK LRVDLMEKVVKSVIPQKYLDERTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAH GGGAFSGKDFSKVDRSAAYAARWVAKSLVKAGLCRRVLVQISYAIGVAEPLSITVFSYGT SNKSEKELLQIIKNNFDLRPGCIVKDLNLKRPIYQKTAAYGHFGRSEFPWEQVKKLTFXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMRLEKCYFCSSTVYPGH GLQFVRNDCKSFRFCRSKCHKAFKKKRNPRKTRWTKAFRKAAGKDLAVDPAFEFEKRRHE PVKYDRELWQNTVKVMKRVEEIKVKRQNQHIMNRLRKGKELRKADDIKEFKQNIHLIKSP A--MVKYKVVMVRHGESTWNKENRFTGWYDSDLSEVGVREANTAGKMLKEKGFTFDIAYT SVLKRAIKTLYLLQEELDLHWIPVERHWRLNERHYGALQGLNKAETAAKHGEDQVKIWRR SYDTRPPGLELSDDRWPGHDPRYAMLDKRLVPAHECLKDTVERVLPYWYDTIVPAIKSGK RVLISAHGNSLRALVKYLDNMSDADIMGTNIPTGIPLVYELDADLKPVNHYYLASEEQVK AAMDKVAAQGKAK----------------------------------VLNGKTVIQADCI IRGDLANVRIGRHCVISSRAVIRPPFKKFSKGVAFFPLHIGDHVLIEEDSVVNAAQVGSY VHIGKNCVIGRRCVLRDCCAIAD---------------------XXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXMGIDICHKKSRKVHRTEPKSQDVYLRLLVKLYRFLARRTNA KFNKIVLKRLFMSKNNRPPLSIARLVRHMKKTGRENKWAVVVGTITDDLRMFDIPKLKIC ALHVTERARGRILKNGGEIITFDQLALKSPKGQNTVLLQGPRKAREAYRHFGRAPGVPHS HTKPFVRAKGRKFERARGRRKSRGYKN--------------------------------- ----------------------------------------------------SRLGHPFI RDGATIRVVLQLLRERFNVYVTEKSGNKMYNDLVALGIPTVVVLDSAVGYVMEKVDLVLV GAEGVVESGGIINKGTYGMSICAKAMNKPFYVVAESFKFTRIYPLN-QDVPNEFKYQASQ EHPLVDYTPPAYITLLFTDLGILTPS-----------MIIPIRCFTCGKVIGNKWEAYLG LLQAEYTEGDALDALGLKRYCCRRMLLAHVDLIEKLLNYAPLEKKSPEPVEGRKHMDVQT ELYLEELSDRVEEADVDCQTDAFLDRPPSPLFIPAKTGMDVATQILDGDLFDFDVEVKPI LEVLIGKTVEQSLLEVMEEEELANLRSQQRAFEELRNAELVEEQRLEEQERRHREEKERR MKQQREILRKERETADKIAARAFSQSYLADLVPSVFGTLAENGYFYDPVERDVEQGFMPW LMDRIEEQLNKSMIGRLVVDGLLREVVRDR------MKARGTFKEYVIVGRRLPSDKERV PPLYQMRIFAPDRVVAKSRYWYFVGMLKKMKKGTGEIVNVKQIYDKKPTKIKNIGIWLRY VSRSGQHNMYREYRDLTITGAVTQCYRDMGARHRARASAIQIMRVEEVPASKTRRTNIKQ FHDSKIKFPLTHRVSKRLHHPRFTTNRPHTYF-AKDEMKQFWKVNQNRPVAPWYIYKPQL TSMLSLQHRISGVAMGIVVNLGAITLVALPYDFTTLMTMLKDQQLNQALLFSLRFILCYP LTYHYINGIRHLAWDAGKGFGLKEVYSTGKFVIASIPFF--------------------- ------------GNMSFYTSEEQIYELFGKCGDVKRVVMGLDKAQKTPCGFCFVEYYNRD EAENSMRYVNGTRLDDRIIRIDWDAGFKEGRQYGRGKSGGQVRDEYRTDYDSGRGGYGKL LQDKI---------LSRHYQSVNCIKFTDDGSHFVSVGEDNLVLVWSLASIFSEHILSSH SLPVTDVYVGCGGARIVTVSLDQTCRVWELCSGQCLSIFKGHSKQVTCLSVSIDGSLLVS GS---------------------------------------------------------- ------------------------------------------------------------ -------HDCSVKLWDIESRQCIRTLSGTV----------TENIIASAALENDKTIKLWR SDVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMAVEFADGVVIGADSRTTTGAYIA NRVTDKLTPVTDNIYCCRSGSAADTQAIADIVSYHLNFHKMQTNEQPLVRTAASIFKDLC YNYRDQLTAGIICAGWDKKEGGQVFTIPLGGMLQRQPFSIGGSGSTYVYGHVDATFREGM N-------------------------------------------------------ALLL ILCCCFCICKKCCKRKKKDDKKKGLKGTVDLKNVQLLGNSYKEKVQPDLDELEVNMEDNE DADSTKSEVKLGKLQFSLDYDFQKGELQVGVIQGADLPGMDMSGTSDPYVKVYVMPDKKK KFETKVHRKTLNPVFNETFTFKVPYAEIGSKMLVFAIYDFDRFSKHDQIGLVKVPLNSVD LGRVVEEWRDLTSPESDSEKDNKLGDICFS------------------------------ ---------------------------------------FEQIQKVTLIITVVDYDRIGT SEPIGRVVLGCNSTGTELRHWSDMLANPRRPIAQWHTLQEMPEKN--------------- -LSTATVINEEVLNGMLKEICAALLEADVNIKLVKKMRENIRSVIDFEEMAAGLNKRRMI QSAVYKELVKLIDPGVKAWAPTKGRSNIIMFVGLQGSGKTTTCTKLAYHYQRKGWKTCLV CADTFRAGAFDQLKQNATKARIPFYGFLTKGSEQESMARLKKLMTIMDS----------- ----------------------NDSELDSHE--GAKLFTRGRVQRVARGAGVSVREVQEL LTQKFAQMVKKMGGIKGLFK-GGDMQKNVPAQMAKLNQQMAKMMDPRVLQQMGGMSGLQN MMKQFQQGAMSIMSYNGAAIVAMRGKDCVAIASDRRFGVQAQTVSMDFQKIFEMGPRLYV GLPGLATDVQTVAQRLKFRLNLYELRENRSIKPKTFMSVVSNLLYERRFGPYFVEPVIAG LDPKTNEPFICNLDLIGCPMITDDFVVGGTCTEQLYGMCESLWVKDLGPEDLFETISQAL LNAVDRDAVTGWGAVVHIIEKDKVTTRTLKARMD-------------------------- ------------------------------------------------------------ --------------------------------------------------RDKWLKPGGL IFPDRATLFICAIEDRQYKDEKINWWDSVHGFDMSCIRKVAIQEPLVDVVDPKQVVTNSC LVKEVDIYTVKLEDLSFTAPFHLQCRRNDYIQALVTFFNIEFTKCHKRTGFST------- -----------------------------NRDLDFTVDVDFRGELSEMVETMHYKMR--- ---------------------------------------------VLMGKNTMMRKAIRG HLVNNPKLECLMNSIKG------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------SAMKGRLIAVIGDEDTCTGFLLGGIGELNKHRQPNFLVVD KNTSVSEIEEAFKSFVNRDDIAVVLINQNIAEMIRHVIDVYEEPVPAVLEIPSKDHPYDA SKDSILRRAKGMFSVDEMRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXMTFITSWEDFAKAAEKLYLADPMKSRFIIKYRHCEGQIVIKMTNDRECLQYR TEHAQDVKKLEKLTSQLMRHMASKELYEEVKLYRTAREREKYDNMADLYAVINTLQCLEK AYIKDCVTPKEYTGACSKLLVQYKAAFKQVQGDEFPSVDYFMKKCKLDCPAAMERIKEDR PITIKDDKGNTSKCIADIVSLFITIMDKLRLEIRAMDEIHPDMRELMETMNRLSILPADY EGKAKVSQWLQTLGGMQASDELTDAQVRQMLFDLESAYNAFNRVLHN------------- ----------------ATALTHALVDHLNAGVAQAYVNQKKLDTETKILQANATQLAKQT IQWLKLVEDFNQSLKEIGDVENWARSMETDMRTISSALEYAYK----------------- -----------------WKMGLKKTARRTKLRSSITPGTILILLAGRHKGKRVVFLKQLA SGLLLVTGPYHLNGCPLRRINQIYVIATKTKIDISGVKLPDRLNDEYFKRKRQK--PQAK GDIFEFKKEEYSVSSERKEDQVDVDRQILDVVRKHEDKKYMFGYLGAMFSLKNKQYPHQM IFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXIVERAISLYPLTNYTFGTKDALYEKDSSVSARFQ RMREEFEKMGMRRSVEGVLIVHEHGLPHVLLLQLGTTFFKLPGGELRPAEDQVEGLKRLL TETLGRPDGGPMDWAIEDTIGNWWRPNFEPPQYPYIPAHITKPKEHKRLFLVQLPEKALF AVPRNYKLVAAPLFELYDNSAGYGPIISSLPQTLSRFNFHYN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------QVVKQCCATDGVEPQYIKDEIL PPFFTHFWNQRMALDRRNYRQLVDTTVEIAHKVGASEIISRVVDDLKDEAEQYRKMVMET IEKIMANLGAADVDSRLEEQLIDGILYAFQEQTTEDVVMLNGFGTVVNALGKRVKPYLPQ ICGTILWRLNNKSAKVRQQAADLISRIAIVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLG SILGALKSIVNVIGMTKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGSEFVS AREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPH-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------LDS FQKVLELEGKDKGEWGFKALKQMIKINFKLGKVEQMMNRYKQLLAYIKSAVTRNYSEKSI NSILDYISTSKQMTLLQDFYETTLEALKEAKNDRLWFKTNTELGKLYFDREEY------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------DQRELIFREREEDLKRLSKPLATSIWD ETLYKAWSSIVYQLIPNVQQLETNLKNFGDIIDADEVLLFERATFLVISHCQRKQHQDVH RFEKISNIIKQFKLSCSKLAASFQSMEVRNSNFAAFIDIFTSNTYVMVIMSDPSIPSAAT LINIKNARKHFEKLERIDQILSFATRLFSVLRFESVIHEFDPYFNYRTTRFLTEEGFYNF HNWFDDRAWYPLGRIIGGTIYPGLMVTSATFYNVLNFFNITINIRNVCVFLAPFFSSLTT LITFLLTKELKDTGAGLVAAAMISIVPGYISRSVAGSYDNEGIAIFCMLFTYAMWIKAVK SGSMFWGAICALAYFYMVSSWGGYVFLINLIPLHVLALMLTGRFSHRIYVAYSAVYALGT ILSMQISFVGFQPVQSSEHMAALGVFGLCQIHAFVDYVRSKLSREQFNLLFKTVVLLVGT VIAMALGKITPWTGRFYTLLDPSYAKNNIPIIASVSEHQPTTWSSFYFDLQMLVFLFPAG LYFCFKKLTDANIFIIIYGVTSIYFAGVMVRLMLVLAPVMCILSGIAISATLTTYMKNLD ITKKAEANYPVKNEIATAVVLLTTAFLVTYTFHCTWVTSEAYSSPSIVLAARSGDGGRII FDDFREAYYWLRHNTPEDAKVMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMAS TEDKAYEIMRELDVNYVLVIFGGLTGYSSDDINKFLWMVRIGGSTDRGAHIKEADYYTPQ GEFRIDKEGSQTLLNCLMYKMCYYRFGEVYTEGGKPTGYDRVRNAEIGNKNFELDVLEEA YTTEHW---------------KLNIRPLMRLICKRFFGDFTGFVSMCVQHIPSPQSNARD KVDHIYTGPQDTELAEAMMECDPDGPLMVHTSKLFPTEDATSFHVFGRIISGTLYANQEV KILGENYSLQDEEDSRFGQVGRLWVSEARYKVEVSRVPAGNWVLIEGIDQPIVKTATITE PSGNEEAFIFRPLKFNTSSVIKIAVEPVNPSELPKMLDGLRKVNKSYPLLTTKVEESGEH VVLGTGELYLDCVMHDLRKMYSEIDIKVADPVVAFCETVVETSSLKCFAETPKKKNKITM IAEPLE----EDIENEVVQISWPREGLGEFFQTKYDWDLLAARSIWAFGPDATGPNILVD DTLPSEVDKGLLGSVKDSIVQGFQWGTREGPLCDEPIRNVKFKILDAVIAQEPIHRGGGQ IIPTARRVAYSAFLMATPRLMGPYLFVEVQAPADCVSAVYTVLARRRGHVTQDAPVPGSP LYTIKAFIPAIDSFGFETDLRTHTQGQAFCLSVFHHWQIVPGDPLDKSIIIRPLEPQPAT HLAREFMIKTRRRKGLSEDVSINKFFDDPMLLELAKQDVMLSYPM--------------- ---------------------KKCNHPDARVSFETFLPILAAISKNRDTTTVEDFIEGFK VFDKEQNGTINSAELRHLLTSLGEKLMDDECEQLLQGQEDAQGNINYEDFVKMVMNGXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXX---------ELGDLVDDSNVLQWEGLIVPENPPYNRGAFRIRIEFPAEY PFKPPKITFKTKIYHPNIDEKGQVCLPIISPENWKPATKTDQVIQS-------------- ---------------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------- -----------------------------------DIIICDTNNHRIQQFNDGSFVKQIG SYGSKKGMLKSPRGVAADHHGQILVADSQN-RIQVFRYDGTFVACIDVSDPYNMAVTRDG HVMLADFKNNCVKVYKYMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSIKKIHAR QIFDSRGNPTVEVDLTSDKGTFRAAVPSGASTGIYEALEMRDKG-KDYHGKGVSQAVNNV NNVIAPALVINLAEQGAVDKIMLDLDGTENKSKLGANAILGVSMAACKAGAAQKGVPLYR HIADLAGNKELILPVPAFNVINGGSHAGNKLAMQEFMLLPTGASSFTEAMKMGSEIYHHL KKVIKDKYGQDACNVGDEGGFAPNIQSNMEGLDLVNTAIEKAGYTGKIKIGMDVAASEFY KKYDLDFKNPKSDPANWLTSDQLAKVYHEFIAKYPVVSIEDTFDQDDWAAWSKLTAIQFV GDDLLVTNPKRVKDGIDKKACNALLLKVNQI----------------------------- ----------XXXTGQIKTGAPCRSERLAKYNQLLRIEEELGSGAKYAGANFRNP----- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------RENVGDLIQETLEAFERMGGE DAFINIKYMIPTYESCLMNAPPSFESFLLFEGEKKITIQKXKKVPNAAVFTINKEDHTLG NSLRTQLLKDPQVLFAGYKNPHPLEHKIVIRIQTTPDYSPQEAITNAITDLISEVSLLEE RFREAVREKQE----------------------------KEPPIKRELLKPRDYKVDLDS KLGKSQVITKTTPAAHQGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMKVERSSLD QVKKRFEMNKRKLEEKRK------------------------------------------ --------------MGCAVSTEDKAAMERTKQIDKILRADGEKASREVKLLLLGAGESGK STIVKQMKIIHEKGYSQK------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------KKLQKCSSKNQGLKEMHTLAINVFSLPGESGFPLNAMYAKPANAQEADVMRAYM LQIRQETGARVCETVFDPATDKPSKWWMCFVKRKFMDKSLSAPGQXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX--------------------------------------QHGFH IHQEGDLGNNCKNTLGHYNPYNKPHGAPTDNNRHVGDLGNLPVDSYVIKDRLVSLFGEHS VIGRSFVIHALPDDLGLGGKPDSLTSGAAGARIAC-------MVNLSVEQLCEVMGRKSN LRNLSVIAHVDHGKTTLTDSLLSKAGIIAADQAGKKCSTDNTKEERERGITIKSTAISMY YELSDEDLGCGFLINLIDCPGHVDFSSEVTAALRVSDGAMVVVDCVSGVGVQTKTVLRQA ISERIKPILMMNKMDRCILEKQMEPEALYISLRNVIERINAIIATYIDEESPLGDITLSP SMGNIGFGAGKHGWGFTLKQFAGFYASKFGVDETKLMKKLWGDHFYNFVRGFNHFVLDPI YKVLEATMQYDDVNRLSDRVGVKLKPVELNLEGKPLMEAFMRKWLPAGDAMLEMITIHLP SPVTAQRYRMELLYEGPHDDEAAVAIKSCDPTGPLMLYVSKMVPSMDKGRFYAFGRVFSG VVTTGQKVRIMTPDYKPIKTIPRTVMMMGANARRVDEVTCGNVVALVGIDKYLIKTGTIT TYEHAHNMRVLKFSVSPVVRVAIDVVNPADLPKLVEGLKRLAKSDPMVECSLD-GGQHVV AGAGELHLEVCLKALEEH-AGVPIKKSDPVVSYRETVTANSDRVCLAKSPNKHNRIFMTA QPLPEGLAEDFDQGKIKTSKDPNERAHYLADKYGYDNREARKIWCFGPEGKGCNFLMDTT KGVQIPQDAKDMIVSGFQWATQEGVLCEENMRGVQFNLTDVRIHSENACRKGGQVIPTAR RAVLAASLTAKPRIMEPIYLVEIQCTQSTLGSVYSVLNQRRGSIFEEIPVVGTPLFNVKA HLPVNESFGFNGALCGQTGGHAFPQCVFDHWQVLVVTDTRRRKGLVEAIPALDVFLDKLX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXNEFTLNQAPTDGISAIKFAPNSSQFLLVSSWDTGVRLYDIASNTMRMKYNHTDPVLD CCFHDAVHSYSGGLDQTLKMFDFNTGTDTRVGTHDAPIRCVEYSPEVNVVVTGSWDSSVK LWDPRTPCSAGTFAQPDKVFTLSVCGDRLVVGTAQRRILVWDLRNMGYVQQRRESSLKYQ TRCIRCFPNKQGYVLSSIEGRVAVEYLDPSPEVQKKKYAFKCHRIKEDGIEKIYPVNAIA FHSLHNTFATGGSDGFVNIWDGFNKKRLCQFHRYPTSIASLAFSHDGAMLAIASSYMYEQ DIPEDNVYIRRVSDQETKPKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXMDDDAETYKLWRVRKTIMQLCHDRGYLVTQDELDQTLDQFRAQFGDKP SERHPSRSDLIVLVAHNDDPTDQMFVFFPEEPKVGIKTIKTYCHRMQEENISRAIIIVQT GMTPSAKQSLTDMAPKYILEQFLEAELKVNITEHMLVPEHVLMTPEEKKELLERYKLKES QLPRIQQGDPVARYFGLKRGHVVKIIRPSETAGRYITYRLVVDKKDNFGTVIGIDLGTTY SCVGVYKNGRVEIIANDQGNRITPSYVAFTSEGERLIGDAAKNQLTTNPENTVFDVKRLI GRAWSEKTVQNDVKFFPFKVINKNEKPHIQINTGTEEKVFAPEEISAMVLIKMKETAEAY LGKKVTHAVVTVPAYFNDAQRQATKDAGAIAGLIVMRIINEPTAAAIAYGLDKREGEKNI LVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLFKKKKGKDLRK SNRAVQKLRREVEKAKRALSSAHQARIEIESLFDGEDFSETLTRARFEELNMDLFRSTIK PVQKVMEDGDLKKDDLHEIVLVGGSTRIPKVQQLVKDYFGGKEPSRGINPDEAVAYGAAV QAGVLSGEEDTGDLVLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQIFSTAADNQPI VTIQVMEGERPMTKDNHLLGKFDLTGIPPAPRGVPQIEVIFEIDVNGILKVSAEDKGTGN KEKIVINNDGNRLSPEDIERMINDAEKFADDDKKVKEKVESRNELESYAYSLKTQIGDKE KLGAKLSSEDKATIEKAVTEQIEWLEKNQDADVEAFKQHKKELEDIVQPIVSKLYQGQPP PGE-------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXX-----------------------------------ILKEEEGRKRVKLLQKQLLEV KRDKEVEVQQRNEMIAHLKDQLQEMKAKTNMEGKYIKKCAEVAVSQTQKKCFLGEKDLRD ETEKLRQNIDEEVRVNAEIESFLRTHKTELEQKVEYWMEKYEKDVEQKQHELDVLKASKA KDLERLQELTKMYAEFEQVVVEDRIEKEKARRKAEQEAEELRAAVRIQSWFRGVMVRRGL GAYSKKKKKKPKIGINGFGRIGRLVLRAALQKVDVVAVNDPFIDLEYMVYMFKYDSTHGR FPGKVELVVDGHAIAVFNEMKPDKIPWGKSGAYYVVESTGVFTTIDKAKAHIAAGAKKVI ISAPSADAPMYVMGVNEDKYTKDQNIISNASCTTNCLAPLAKVIDDKFGIEEGLMTTVHA MTATQKTVDGPSSKAWRDGRGAAQNIIPASTGAAKAVGKVIPNLNGKLTGMAFRVPVPDV SVVDLTCRLKKAATYDEIKAVVKSPLGAYLGYTEDQVVSSDFIGDTRSSIFDARAGIALS PTFVKLISWYDNEYGYSHRVVDLITYIAK------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------GITAGGPPGTGKTLIARAVANETGAFFFLINGPEIMSK LAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKKEKTHGEVERRIVSQLLTLMDGLKQ RSHVIVMAATNRPNSVDSALRRFGRFDREVDIGIPDATGRLEILRIHTKNMKLADDVDLE QVAAETHGHVGADLAALCSEAALQQIREKMELIDLEDETIDAEVLDSLAVTQEDFRWALS KSNPSALRETAVEVPNVSWEDIGGLENVKKELQELVQYPVEHPDKFMKFGMTPSKGVLFY GPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFD ELDSIAKSRGGNVGDGGGAADRVINQLLTEMDGMSNKKNVFIIGATNRPDIIDPAILRPG RLDQLIYIPLPDDKSRISILKANLRKSPVSKDIDLDYLAKNTHGFSGADLTEICQRACKL AIRQSIEAEIRRERERAANPDETDPVPEITRDHFEESMKFARRSVTDNDIRKYEMFAQTL QQSRGFGSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- --------------NRIFHPNIDEVSGTVCLDVINQAWTALYDLSNIFESFLPQLLTYPN PIDPLNGDAAAMYLHKPEDYKKKVAEYVKKYATEEALRE--------------------- ------------------------------------------------------------ ----------------------------SSKHSFNKLDAWLNELETFSTKHDIVQMLVGN KIDKEKREVSREEGLKFARKHHMLFIEASAKTKEGVQCAFEELVEKIIQTPGLWETEGIT LTS--WSIINGSFCSFKVKTKPQKFCRNEYSLTGLCNRSSCPLANSQYATVREEKGVIYL YMKTIERAAFPRNMWEKVKLSKNFEKAL-QIDEHLLYWPRFIRNKCKQRFTRITQYLIRM RKLMLKRSKKLVPLSRKVERRETRREEKALVAAQLDNAIEKRKEYRLR------------ ---------------------------------------LMQTRFQAEPRMKKFSIYRWN PDKAGDKPHMQTFEVDLNTCGPMVLDALIKIKNEIDPTLTFRRSCREGICGSCSMNIAGT NTLACLDKIDANTSKATKIYPLPHMYVV-------------------------------- ------------------------------------------------------DRGDDF PEDRLAKLQDQWSVYRCHTIMNCTKTCPKGLNPGLAIAELKKMML----------DIRPN QTIYINNLNEKIKKDELKKSLYAIFSQFGQILDITALKTLKMRGQAFVIFKDINSATNAL RSMQGFPFYDKPMRISYSKKDSDVIAKMKGTFVERPKKKKAEETRGDSKRK--------- ------------------------------------------------------------ -----------------MDNQGRKVVICDNGTGFVKCGYAGSNFPAHIFPSLVGRPIIRS SVKVGDIEIKDLMVGDEASQLRSMLEVNYPMENGIVRNWDDMMHLYDYTFGPQKMNINPR ECKMLLTEPPMNPTKNREKMVEVMFEHYQFEGLYVAIQAVLVLYAQGLLTGVVVDSGDGV THICPVYEGFSLPHLTRRLDIAGRDITRY------------------------------- ------------------------------------------------------------ -----------------------------LPSRLEREIKQLYLERILKGDTEKLSKFKIR IEDPPRRKHMVFLGGAVLADIMKDKDTFWMTRKEYQEKGLNVLEKLGVS----------- ------------------------------------------------------------ ----------------------------------------------------GVMPDGTS RFTCKGQSLYHFMGTSTFSEYTVAAEISIAKVTEKAPLESVCLLGCGISTGYGAALNTAK VEKGSTCGVWGLGAVGLAVLMGCKRAGASRIIGIDINQDKFEIAKQFGATECINPKDYEK PIQQVLVDMTDGGLDYTFECIGNVGTMRAALEACHKGWGESVIIGVAAAGKEISTRPFQL VTGRTWKGTAFGGWKSRDSVPKLVEEYLEGHCKVDEFITHTMPLDKINEGFDLMHEGKSM DAYDVIANQPVVIDNGSGVIKAGFAGDQVPKYHFPNFIGRPKHVRVMAGALEGDIFLGPK AEEHRGLLSIKYPMEHGIVTDWNDMERIWQYIYSKDQLQTFAEEHPVLLTEAPLNPRRNR EKAAEIFFETFNVPALFISMQAVLSLYATGRTTGVVLDAGDGVTHAVPIYEGFAMPHSIM RVDVAGRDVTRYLQLLLRKEGQNFHTSAELEIVK-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------RRYCPNSVLVIVDAKPKDLGLPTEAYIAVEEVHDDGTPTSKTFEHIPSEIGAEE AEEVGVEHLLRDIKDTTVGSLSQRITNQLMGLKGLNGHIQDIHSYLEKVVSGNLPINHQI IYQLQDIFNLLPDVNLQTFVKAVYVKTNDQMLAVYLASLIRSVIALHNLISNKIQNRDAE KNEGKEKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXX-----RRVILNDPSQLPNDYSTTPGGTIFSTTPGGTRIIYDRAFLMKCKESPLA KTP-------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRQFSSSNKVA VMGASGGIGQPLSLLMKQNPLISHLALYDIVHTPGVAADLSHISTNAKVTGHMGPGQLKD CLEGCELVVIPAGVPRKPGMTRDDLFNTNASIVRDLADACARFCPKAILAIISNPVNSTV PIASEIFKLRGVYDPNRIFGVTTLDIVRANTFISENKGLDVSKVNCPVIGGHSGVTIVPI ISQCTPPVSFPQDEREKLTTRIQNAGTEVVEAKAGAGSATLSMAYAGAKFADSVLEALNG EQGVVQCAFVASSESEAAYFSTPVLLGRNGLENNLGLGKMIEYEVELVKKAMPELTGNIQ KGIDFVANNIDRGKDFNIKTRIITDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFAS TLSHLRRLNSPVGRDGKLARPRQLHNTQWGMICPAETPEGGAVGLVKNLALMAYISVGSQ PSPILEFLEEWSMENLEEISPSAIADATKIFVNGCWVGIHRDPEQLMSTLKKLRRQMDII VSEVSMIRDIRDREIRIYTDAGRICRPLLIVENQKLMLKKRHLDLLKEREYNNYSWQDLV ACGVVEYIDTMEEETVMIAMTVDDLQEKGVGYCSTYTHCEIHPSMILGVCASIIPFPDHN QSPRNTYQSAMGKQAMGIYITNFHVRMDTLANVLFYPQKPLVTTRSMEYLRFRELPAGIN SIVAIASYTGYNQEDSVILNESAIDRGFFRSCFYRSYKDSESKKGLDQEEIFEKPDPNFV QGMRPAVYDKLDEDGIIAPGTRVSGDDVLIGKTITLPDNDDELGATATRYTKRDASVFMR RTETGIVDQVMVTINQEGYKFCKXKKKKVKTPQIGDKFASRHGQKGTCGIRYRQEDMPFT CEGLTPDIIVNPHAIPSRMTIGHLIECLQGKVSANKGEIGDATPFNDTVNVQKISNLLHE YGYHQRGNEVLFNGHTGRKLNAQVFLGPTYYQRLKHMVDDKIHSRARGPVQILNRQPMEG RSRDGGLRFGEMERDCQIAHGAAQFLRERLFESSDAYRVHVCNICGLIAIANL------- ------------------------------------XXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSKVTFKI TLTSDPKLPYKVLSVPEQTPFTAVLKFAAEEFKVPAATSAIITDDGIGINPAQSAGNVFL KHGSELRLIPRDRVGHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGLLTILKKMKQKEKEVRLL MLGLDNAGKTTILKKFNGEDIDTISPTLGFNIKTLEHRGFKLNMWDVGGQKSLRSYWRNY FESTDGLIWVVDSADRRRLEDCKQELDALLLEERLAGATLLVFANKQDLPGALPAEEIKD ALDLDNIKSHHWLIQDCSAVTGENLLEGIDWVVDDIASRIFTMDHTKKRICYYYDGDIGN YYYGQGHPMKPHRMRMTHNLLLNYGLYRKMEIYRPHKATQEEMTKFHSDDYIKFLRSIRP DNMSEYNKQMQRFNVGEDCPVFDGMY---------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------LPYNDYFEYYGPDFKLHISPSNMANQNTGEYLDKIKTRLFENMRMLPHVPGVQM QDIPEDALNDDANPDERISIRSSDKRIACEEEFSDSEDEGSGHRRNRHNHRRDHK----- ------------------------------------------------------------ ------------------------------------FGIGAFPFGFFASTFNLADGRPGA PAPGTPQATEEQFLSKIFLWIAVLFIFWLMIA---------------------------- --------------------LELRHTLEGHQLGVISVDINLQGTLAVSSSLDSHIRIWDL ETGKQVKCIDAGPVDAWTVCFSPDSRFLASGSHTGKVNLFGVDSGKMESALDTRGKFTLS VAYSPDGKYIACGAIDGIIHIFDMITGKLLEGHAMPIRSLCFSPDSQLLVTASDDGHIKI YDVQHANLAGTLSGHGSWVLNVAFSPDNTTFVSSSSDKTVKIWDAGTRQCVHTFYDHLDQ VWCARYNGTGTKIVSVSDDRAVHVYECP--SDEEYDNQAVKYFQRTDIDCWDIRRVLTNM QGEDMVPEPKIIISALHAIRRINDYALAVRYLEAVYDKCGNRVNQIWPYILQEIQPTLTE LGISSPTEM---------------VVRVRGLPWSASTEEVSNFFEDCNILGGHNGIHFTF VRDGRPSGEAYIEMASEDDVEKAVTKNNGHIGKRYIEVFQSKRSEMEWVVKRSGPNQDNV VRLRGLPFGCTKEEIAHFFTGLEIVPDGITLIKDQQGRTTGDAYVQFASQEITERAQLKH KEKIGHRYIEIFKSSLAESGTNHNSQTGHSVHLRGLPFAANEQDILEFFRPLNPVNVVIH YQSGRATGECDVDFATHEEAKQGMKKDRSMMQHRYIELF--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------GPSKIEKAKIGLIQFCISPPKTDMENQVIVSDYTQMDRVLREERQYI LNIVKQIKKAGCNVLLIQKSILRDAVNDLALHFLAKMKIMVVKDIEREDIDFICRSLNCK PIASLDHFQPEMMGSAELVEEVQTGASKVVKVTGIVNPGKTVSVIVRGSNKLVLEEADRS IHDALCVIRCLVKKRALIAGGGAPEIEVALRLAEYSNTLSGMEQYCFRAFAEALEVIPFT LAENAGLNPISTVTELRNKHAQGEKTAGINVRKGAITNILEENVVQPLLVSTSAINLAAE TVRSIMKIDDIVNVMMILLEINNRIIEETLTLKFTNALAGNKPDLLDVTVADFDGVLYHV SNPDGDKSKIRVSISLKFYKDLQEHGADELITREYGPFLSSPEDGYNVSLIFDDNIPPNH EEVVKKAGLLKRNCFASVFEKYFEFQEKHKRAIIHYREDETMYVDARKDRVTVIFSTVFK DDDDIVIGKVFMQEFKEGRRRYQQAPQVLFSHREPPLELQGTDAVTGDNIGYITFVLFPR HEARENTIDLIHTLRDYLHYHIKCSKAYIHSRMRAKTSDFLKVLNRARPEPKKKE----M LMFCPICANVLVVEEGPNCYRFACNTCPYIHNISRKISNRKYPKLKEVDDVLGGAAAWEN VDSTAETCPKCSHGRAFFMQIQTRSADEPMTTFYKCCNMSCGHRWRKTTFGPLKDEDRVF TNLYGRHDWRLKGAMKRGDWYKTKEIIQKGFEWIQGEIKASGLRGRGGAGFPTGLKWSFM NKPDDGRPKYLVVNADEGEPGTCKDRDIMRHDPHKLVEGCLVAGSAMGARAAYIYIRGEF YNEASNMQIAINEAYQAGLLGKNACGSGYDFDVFMHRGAGAYICGEETSLIESLEGKQGK PRLKPPFPADVGVFGCPTTVNNVESIAVAPEICRRGAEWFASFGRPRNNTVLMDFDDLVQ NQTGLGTAALIVMNKSSDIVRCISRLADFYKHESCGQCTPCREGCNWMAKIMHRFVVGKA KPDEIDMLYEMSKQIEGHTICALGDGAAWPVQGLIRHFRPELEARMKAYADSQ------- ------------------------------------------------------------ ------------------------------------------------------------ AMSNTTDVETTRCAAGTLHNLSHHRQGLLAIFKSGGIPALVKLLSSSVESVLFYAITTLH NLLLHQEGSKMAVRLAGGLQKMVALLQRNNVKFLAITTDCLQILAYGNQESKLIILASGG PGELVRIMRSYTYEKLLWTTSRVIKVLSVCSSSKPAIVEAGGMQALAMHLGHQSQRLVQN CLWTLRNLSDAATRNDALEGLLQMLVQLLASNDVNIVTCAAGILSNLTCNNQRNKVTVCQ VGGIEALVRTILQAGDREDITEPAVCALRHLTSRHPECEMAQNAVRLHYGLPVLVKLLHP PSRWPLIKAVVGLIRNLALCPANHAPLREHGALPRIVQLLIRAHQDTQRSQSAYVDGVRM EEIVEGTVGALHILAREAHNRAVIRGLNCIPLFVQLLYSPVENIQRVAAGVLCELAAEKE GAEIIEQEGATAPLTELLHSRNEGVSTYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRNE PXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXX----------------------------------------------------- ------------------TPGLLRVLNKQLGPKKTVTLESIEEKWVELALPKEQFDELVR IGSFGGDVEWLKFFAIGSSALGENITDAMKTVCEILTADPDGGPARIPFPQFQELYKYLA QIDGEIPQE----------------------------------GKIDGAQREQLMEQVKA QMAIVNAQELLQKMSDKCFKKCVTKPGTSLDNSEQKCVAMCMDRYMDAWNLVSKTYSNRL QKERSKMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------KCDDD SEPSNGIAANTKECPRCNITIEKDGGCNHVVCKQCKFDFCWVCMGDWQPHGSSWYNCNRF DEDEAKKARDAQERSRSALQRYLFYCNRYMNHMQSLKFEHKLYTSIKLKMEEMQQHNMSW IEVQFLKKAVDVLCQCRQTLMYTYVFAFYLKKNNQSIIFEENQKDLENATEQLSEYLERD ITSDMLIDIKQKVQDKYRYCESRRNVLLDHVHEGYEKELWDYQDXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------------KQ EKIKPQEQLTLEPYERDHAVVVGQYRPPPK-MDPKNYKDLVGRLGRGGKGLGAGAGVLLA AGGALYGLYNAMYTIEGGHRGIVYSRIGGIQEDVYREGLHFRVPWFEYPIIFDVRAKPKK VSSPTGSKDLQMVNIALRVLSRPDSSKLPTIYRQLGQDYDERVLPSICNEVLKSVVAKFN ASQLITQRQAVSLMVRKNLTERARDFNIILDDVAITELTFGREYTAAVEAKQVAQQEAQR AQFFVERAKQERQQKIVQAEGEAKAAQMMGESISLNPGFLKLRKIRAAQTIARTIAQSQN KVYLNAGTLMLNLSDKEFEDNL-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------QRRVAITAGGKQVLVCGYGEVGKGCCAALKGLGAITMVTEIDPICALQATMDGF RVVTLNEVVKQVDVVVTCTGNKNVVTREHMDRMKNGCIVCNMGHSNTEIDVNAIRTAELT WERVRSQVDHVIWPDGKRIILLAEG--VNLSCSSIPSFVVSITAATQALALIELFNAPNG RYKQDVYLLPKKMDEYVASLHLPTFDAHLTELSEEQAKYLGLN------------PDPDA IKMFVGQVPRSMDENDLRKMFEDFGPIYQLNVLRDKVTGQSKGCCFITFYTRKAALDAQN ELHNIKTMPGMQHPVQMKPADSEKRNIEDRKLFIGMLSKKCNENDVRMMFAPFGTIEECT VLREQSGQSKGCAFITYTNKQSATNAIKSMHHSQTMEGCRSPLVAKFADTQKEKEMKKLQ Q----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------GIAATLAWWLVW PLEYMKAQVQGKRGGFFALYRGLGPGTIRSFLSNGSSMVVMTYAQKKVSASDQEYLRLTQ AISQNIQKISQNVAQVQRMVNQLGTAQDNEKLRDNLHQITHYTNQLAKDTNKYMKDISHL QSEQRQRKMQKERLMNEFTSALNNFQSAQRKAAEKEKASVENVDLQLIQEREQSIRKLEA DIMDVNQIFKDLGMLVHEQGDMIDSIEANVENVHVEQGTQQLSKAKDYQSKARRKKIMLV VICIVVLVVVAIILGIIFGMVNVMKGVMVECDPAMKQFLLHLDDTNALGKKFVIQDLDDT HIFVASDIIPILQE---------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------L EQEELDKQLLEVADLPSVPTAEDDEMKELAAWATSMQRFHNRVRQILMASGSTTFTKIVN KWNTALIGLMTYFREAVVNTQELLDLLVKCENKIQTRIKIGLNSKMPSRFPPVVFYTPKE LGGLGMLSMGHVLIPQSDLKWSKQTDVGITHYRSGMSHDEDQLIPNLYRYIMPWESEFID SQRVWAAYAL-------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------TIHKTFEGNLTTKPINGAIFIFNPRTGHLFLKIIHTSV WAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKG SELQLPSQACLKVEKFGDLILKA------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------IKETGYTYILPKNVLKKEKSISDLRAQISG YLYGVSPPDNPQVKEIRCVVMPPQWGTHQTVHLPNLSPNHEYLKEMEPL----------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------SCYTATRPNLMLTKNTKVICQGFTGKQGTFHSAQAI EYGTNIVGGTSPKKGGQMHLGLPVFKNVKEAKDATGADASVIYVPPSLAAKAIEEAIDAE IGLVVVITEGIPQQDMVRVKHKLLRQNKTRIIGPNCPGIIKPGECKIGIMPGHIHKKGRI GIVSRSGTLTYEAVHQTTLVGLGQTLCVGIGGDPFNGTNFIDCLEVFLNDPDTHGIVLIG EIGGQAEERAAEYLKKHNGPN--------------------------------------- ----------------------------PSNESLKCTLCQERLEDTHFVQCPSVPEHKFC FPCSRESIKSQGAGSEVYCPSSKKCPLVGSNVPWAFMQGEIATILGXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKT CPLLLRVFCNTFRHNPVSEYSRGNTPTNELQIYTWMDATLKELTSLVKEVNTDARRKGTF FDFAMVCPEIRQPVYRVKEIGTTCAGRKGTDDNVTLISKRFKIGDYIDIAISPP-GLGKT LQTISLLGYMKHYRNIPSPHLVIVPKSTLSNWMAEIKRWCPSLKPVCLIGDAEKRAALIR DTIMPGEWDICVTSYEMVIREKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKSTNR LLLTGTPLQNNLHELWALLNFLLPDVFNSADDFDGWFSANECFENETLVQRLHSVLRPFL LRRIKIEVEKKLLPKKETKVFIGLGKLQREWYTKILLKDIDVVNGAGKSDKMRLLNILMQ LRKCANHPYLFDGAEPGPPYTTDYHLVGNCGKMVVLDKFLPKLQENDSRVLIFSQMTRML DILEDYCAWRGYNYCRLDGQTPHEDRQISIDEFNAPNSKKFIFMLSTRAGGLGINLATAD IVILYDSDWNPQVDLQAMDRAHRIGQTKQVRVFRFITENTVEDRIVERAEMKLRLDNIVI QQGRLVDSNTNKEVLNMIRHGANHVFASKDSEITDADIDLILEKGEKKTEELRKKMETLG ESSLRSFSLDTNESSVYQFEGEDYREKQKLGGIGHWIEPPKRERKANYAVDAYFREALRT SEPKAPKAPRPPKQPNVQDFQFFPPRLFELLDREIYCYRKSIGYRVPKNLDLGSDAERVR KDEQKKIDEAEVLSEDEIAEKEDLLIGFTNWSKRDFNQFIKANEKFGRDDIDSICREVEG KTPEEVMEYSSVFWERCNELQD-------------------------------------- ------------------------------------------------------------ -------------------------------------AEQVEQGEEGGLPSQLEILDEDS GFRTITEYKINDEGKKVKVVKTYKIETRKVSKSVARRKAWRKFGAAARDPAGPNPANTIE DVFMAFVHNKES-EDDPLAKLKVSCRICKGDHWTTRCPYKDTLQPLQETLSKPGKYVPPS LREGANRRGESMHSDEASTIRVTNLSEDTRESDLQELFRPFGTISRIYLAKDKITGQSKG FAFINFHHREDAARAISGVSGFGYDHLILNVEWAKPSXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXLIKPANKEELHSSQWPLLLKNIERLNIRTAHYTPIPAGCSPLKRPIDEYVKTGFLNL DKPSNPSSHEVVAWIKRILRVQKTGHSGTLDPKVTGCLIVCIERATRLVKSQQGAGKEYV CIFRLHSAVEDERKLARAVETLTGALFQRPPLISAVKRQLRIRTIYESKLLEYDSERNMG ILWVSCEAGTYIRTLCVHLGLMLGVGGQMQELRRVRSGIQNEKDNLVTMHDVMDAQWVYD HHKDESYLRRVIKPLEALLTSHKRIMMKDSAVNAMCYGAKIMLPGVLRYDDGIEINEEIV MITTKGEAIALAIALMTTAVIATCDHGIVAKLKRVIMERDAYPRKWGLGPKASMKKKMIK EGLLDKHGKENEKTPKGWSSSYTDYNIKRKMKDSQPSGKKEKKKKKKKMAECDWDRKKQP KSGQLRSQQALNAAQRSGVAIDTSKKYSAGQNKQHSANKNTARLDRETEELHHDKIGLDV GKLVMQGRQAKKMTQKDLATKINEKQQVINDYEGGRAIPNQTVLSKLERVLEMKLRGKDK GQPM------------------------------------FSGYGDKDARVTAAIASNIW AAYDKNGRAAFNEDNLQYILMDCEEGKVAITRVANLLLCIYAKESV-------------- ---------------------KKRTLDDAYAPPANFLEIDVTNPEGKKRYTDYEVRMRTN LPVFKVKESSVRRRYSDFEWLKNELERDSKIVVPSLPGKAWKRQLPFRQDEGIFDDAFIE ERRKGLETFVNKVAGHPLAQNEKCLHMFLQEPVIDKNYVPGKVRTTXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMATSKGANNYNRQNWEDSDFPILCQTCLG DNPYIRMTKEKYGKECKICARPFCVFRWCPGARMRFKKTEVCQTCSKLKNICQTCLLDLE YGLPVQVRDAALKIQDEMPKSDVNKEYYTQNMERELANNDGTNPVGAVGKSQAPSDILLK LARTTPYYKRNRPHICSFWVKGECKRGEECPYRHEKPTDPDDPLADQNIKDRFYGMNDPV AEKLMKRYSAIPKLEPPED---------------------------------------ED LKLFKDYKTLGDLGITSSTARAQDPASVGLAYREFENLEVTPYSSPPELPDVMKPQADSS SHPQE-LFRYHAVLMRARFDEHKDEDMIKAKQLLKAGEAELAAKRHP------------- -------------------------------------------------XXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------------- ---------------------------------------------------------QNV HITLRILFRPIPDKLPDIFQNLGVDYDDRVLPSITNEVLKAVVAQFDASELITQRELVSQ QVNEELTNRGAHFGLILDDIALTHLTFGKEFTEAVELKQVAQQDAERARFIVEKAEQQKQ AAIATAEGDSIAAEMLAKAFGDAGDGLVELRKLEAAEDIAYQLSRSPNVVYLPQGQQTLL SLP--------------------------------------------------------- ---IKKELAAVRTVCSHIENMMKGVTYGXXXXXXXVYAHFPINLAISEGNTLVEVRNFLG EKFTRHVPLRPGVSITSSTAQKDEIILEGNDIE--------------------------- ------------------------------------------------------------ VKQMKIIHEKGYSQEECLQYRPVVYSNTIQSMIAIIRAMGQLKIEFGHPDRADDARQLFA LAGNAEDGELSADLAAVMKRLWKDSGVSECFGRSREYQLNDSAEYYLSALDRISISGYIP TEQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFIVAMSE YDLSLAEDQEMNRMMESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKRK---------- ------------------------------------------------------------ --XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX-----------------------------------------CPTCRGPLGNIRNLAM EKVAATVMFPCKYSQSGCPMTLLHTDKTDHEETCEFRPYCCPCPGASCKWQGSLEQVMP- ------------------------------------------------------------ ---------------YRLELNGHRRRLTWEATPRSIHDGVQSAILNSDCLVFDTNIAQLF ADNGNLGINVTISMCXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XX-LELLSDQGFRIDGRRPHELRRIQCKMGVFGQADGSAYIEQGNTKVLAAVYGPHETR- ERSKLDKVLINCQYSMATFSTGERKRRPRGDRKSQEMTQHLQQTFDAAIMTHLYPRSQID IYVEVLQSDGGNYCASVNAATLALIDAGIPMKDYVCACSASFIEDSPLVDINYLEESRGP ELLVATLAKSDQIVFLEMNGRLHEDNLSKVLDTATKGCKDVYTILDQVVRDMAGNYYFAV VGHHDNPVFEMEYFPSNKANEPKKDDHRHLNQFIAHAALDLVDEQMWMTNSMYLKIVDKF NEWFVSAWVTAGRMRFLMLHDVKNEDGIKNFFTDMYEIYIKH------------------ -----------PTQVRFAHTDIRVPSFDYYRRDSVKDIRKSFTYVFAAAGGLGGAYVGKA MVVDLISSMSATADVLALATIEVKMDDVPEGKSMTFKWRGKPLFIKHRTAEEIERERGVD LSTLRDPEHDNDRVKAPEWLVLLGVCTHLGCVPIADQGEYGGYYCPCHGSHYDAAGRIRK GPAPLNLEIPPWEFDGDKMVI-G------------------------------------- -------DKMGYNIGVRLIEDFLARANVGRCHDFRETADVIAKVGFKMFLGVAPVVTNWS PAGDEFSLIMETNP---------------------------------------------- -----------------------ENVKAFLAQAKEDFQDKWDKPAQNTAGLDDFDRIKTL GTGSFGRVMLVQHKATREYYAMKILNKQKVVKLKQVEHTLNEKRILQAIAFPFLVSLEYH FKDNSNLYMILEFVTGGEMFSHLRRIGRFSEPHSRFYAAQIVLTLEYLHHLDIMYRDLKP ENLLIDA----------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -MLADTLLIVFISICTALLGEGLTWLLVYRTETYIKLKAEVEKQSKKLEKQKESGAEASD RSHKKKIERQEEKLKNNNRDLSLVKMKSMFAIGFAFTALLSMFNSIFDGRTVAKL----- ----------------------------------------------------------CV KYFDTWSETDQVDFVEHLISRMCHYQHGQINTYLKPMLQRDFISALPAKGLDHVAESILS YIDASSLLSAELVCKEWYRVISDGMLWKKLIERMVRTDPLWQGLSDRRGWGQYLFRPKPG EPQKDHKFYRKLYPQIISDIEKIENNWRTGRHTLQRIHCRSETSKGVYCLQYDDNQIVSG LRDNTIKIWDRNNLECVQVLTGHTGSVLCLQYDENIIISGSSDSTVRVWSVKTGEMLNTL IHHCEAVLHLRFSDGIMVTCSKDRSIAVWDMQSPTDINLRRVLVGHRAAVNVVDFDQKYI VSASGDRTIKVWSTSSCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACL RVLEGHEELVRCIRFDNKRIVSGAYDGKIRVWDLTAAMDPRAPAGTLCLRTLVEHSGRVF RLQFDEFQIVSSSHDDTILIWDFLNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXAEGETSADRNVEIWKIKKLIKSLEAARGNGTSMISLII PPKDQISRVAKMLADEFGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVIYCGT IVTDEGKEKKVNIDFEPFRPINTSLYLCDNKFHTEALTALLADDNKFGFIVMDGNGSLFG TLSGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAEVAVTLYITNDKP NVAGLVLAGSADFKTELSQSDMFDPRLQAKILKVVDVSYGGDNGFNQAIELASEALSNVK FIQEKKLIGKYFDEISQDTGKYCFGVVDTLKALEMGSVEILIVWENLDIQRYVLRNHQTD EDKTLFLKPEQEKEKTHFTDKDSGVELELQDSQPLLEWFANNYKSFGATLEIITDRSQEG AQFVKGFGGIGGILRYQVDFQSLEVVDDLDGDFDLDDYXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXPPFRAFIPHVPFDLAQCESAFPRPKPAPEEKNLSDALLKRNADLTPS TQEQSSVLNLVTKINGVLDNLIISPGSFDAAQLEEVRQVGSHKKGTMIIGHNVADLVVIL KTLPTLEAVNALGTKVQEDLKASDPNEVLSMLPNDSGFEVSSAEATAKVLITTIPPNLKK LDPELHLDQKLMQGHLAAIRHARWFEENAFHSSIKVLIRLLRDLKNRFEGFEPLTPWIID LIAHYAIMNNPSRQPLPINVAFRRCLQLLAAGFFLPGSAGITDPCEQGNIRIHTVMTLEQ QDQVCFTAQTLLRVLSHGGYKQILGLEGNASIATEMSVWEGVVVTPSDKAYEK---VVRL IEQYLKENNLLRTLSLLQEESGISLNTVDSVDSFVSDINNGHWDTVLQAIQSLKLPDQKL IDLYEQIVLELIELRELGAARSLLRQTDPMIMMKQNQPDRYVHLENMLARSYFDPREAYP EGQTKERRRAAIAQALSGEVNVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAV REQEDEKYPTQLSKTIKFGQKS-------------------------------------- ---------------------------------------------------AHSKVDTCV NFSKDSSQLLSASFDQTIRIHGLKSGKTLKEFRGHTSFVNDVVFTPDGHHILSASSDGTI KVWNIKSTECQNTFKSLGGSAGADITVHSVHPLPRNVEQFVVCNRTNTVVIMNMQGQIVR SF---------------------------------------------------------- -----------------------------------TPKLNTFVKYAKVELTPPSQMPQVQ EGFQKLLLARTGGWKNLTVTQTAAVAVEIACWFFIGECIGKGSLVGYNIPGAYQVELHXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXX-ELVRGQLFEVAPRYTQLTHIGEGAYGMVVSAYDNVTKT KVAIKKISPFEHQTYCQRTLREIKILTRFKHENIIDIRDIIRSPTLDEMKDVYIVQCLME TDMYKLLKTQQLSNDHVCYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFG LARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDVWSVGCILVEMLSNRPIFP GKHYLDQLNHILGVLGSPSQDDLSCIINDKARGYLQSLPFKPKVPWKQLADPKALDLLDK MLTFNPGKRITVEEALSHSYLEQYYDPADEPVAEEPFTFETELDDLPKERLKELIFQETL NLSER------------------------------------------------------- ---------------------------FKNMVPQFAIVVRSGDKLNIRAEELVLGDIIEV KFGDRVPADIRVMNCHGFKVDNSSLTGESEPQSRSPEFTNENPLETKNLAFFSTNAVEGT CCGIVISIGDRTVMGRIANLASGLEMGETPIHKEINHFIHII------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------SFKKLSKGKKIALS AAAGGVGVGVALTDLQLHPPHLPWSHNGTFSSLDHAGIRRGYQVYKQVCAACHSMDYLCY RNLIGVCMTEEEAKAEAEEVLVTDGPNDLGEMFQRPGKLSDRFVAPYANDEAAKAANNGA LPPDLTMIALARHGGEDYIFHLLTGYCDAPAGVEVAEGQFYNPYFLGGKISMAQALYNEI IEYEDGTPATQSQTAKDVCTFLRWASEPEHDDRKRMGLKGLIMVLIAMVYHYKRFKFSTM KSRKF------------------------------------------------------- -----------------------------------------------SGNTGIGLGMVAA VKGYRMIAVMPEKNSNEKVYTMRAEGVELVRTPSAASYYTPESAYRIAYKLGDNIPNSVV LD---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------MSDLGS DEEQGPDLGEYEGERNEKEKRHGHGKATLPNNDTYEGSYENGKRHGHGTYRFKNGARYIG EWSKNKKHGQGLFIYPDGSKYEGSWVEDQRCGFGKYCYVNGDIYEGEWQNHVRHGQGVYT YAETGSKYTGTWKEGKREGAGELIHSNHKYVGQFREDRMQGKGKYVFDIGCQQQGEYIXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------------------- -ICEQSSKVVTFIDLAGHEKYLKTTVFGMTGHAPDFSMLMIGANAGIVGMTKEHLGLALA LSVPVFVVVTKIDMCPPNVLQDTLKLLQRILKSPGCRKIPVLVQNTDDVVCTATNFTSER MCPIFQVSNVNGENLDLLKMFLNLLSTRLHSEPAEFQIDDIFSVPGV------------- ------------------------------------------------------------ -------FEADIYLLFHANSISKGFQSTIHVGNVCQTAIIETMDKESIQTGEKAIVVFRF IKNPEFVKVGSRLLFREGRTKGMGEITRIIP-----------------XXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX------------------------------------------- ------------------------------------------------------------ ---------------------------------------VSDTLPTGQLSNVPWRRTGVK YTNNEAYFDVIEEIDAIIDRSGATVFAEIQGYIDCLIKLSGMPDLTLSFVNPRLLDDVSF HPCVRFKRWESERILSFVPPDGNFRLISYHIGSQNMVAIPVYLRHSISFRDGSSGRLDIT VGPKQTMGKTVENVIIEIPFPKAVLNVTATPSQGKYSFDPVTKQMSWDVGKIDTGKLPNI KGTINLQSGSPVP----------------------------XXKYKPFKGVKYVTKAGKF QVRTMATYVRPSTRHATSDWFTSNYTISTNAERQRGASHDVRQESRFLRNETSNKTKWDQ LDNNTRLADRVDNIRTWKDILTRTLANIDKEISDLNESKDCLENSLEAKNLPTEVNVENL VTREGRQRIDVVEDEVEDQLHKEQEVIEGIKKQLQGKIDEAFEQLCVLQEARQQILADLQ DKNIALGIDVDQYNLTENSAGISYKPDPTRVPKGSTNPQNWEDFSRYNKDRAEAEMGASK HLREAIHHTLQQTDNDLA------------------------------------------ ------------------------------------------------------------ -------------------------------------------------TNLKDVLANKI PAEQKRVSDFRKQHGKTVVGEVMIEQIYGGMRGIKGLATETSVLDPDEGIRFRGYSIPEC QEKLPRAPGGAEPLPEGLFWLLATGDLPTEEQVKAVSKEWANRADLPSHVVTMLNSMPSK LHPMSQFSCAITALNSESKFVQAYQQGVNKATYWEYAYEDSMDLIAKLPTVAAIIYRNLY RDGTSVGAIDPEQDWSANFVNMLGYEDSKFTDLMRLYLTIHSDHEGGNVSAHTTHLVGSA LSDPYLSFAAGMNGLAGPLHGLANQEVLLWLTKVMVSDEVLTEFIWSTLKSGQVVPGYGH AVLRKTDPRYTCQREFALKHLPDDPMFKLVSQIYKLVPNILLEHGKAKNPWPNVDAHSGV LLQFYGMKEMNYYTVLFGVSRSLGVLSSLIWDRAFGLPIERPKSLSTDKLMELVNXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXX--------------------------------------------------- ------------------------------TFYTMFNRSPVGKNFVQICTTTPCMLGGVG SDIILETLKKKLGIEVGETTKDKMFTLAEVECLGACVNAPMVQINDDYYEDLTPKDMEEI LDDIIAGRKPKPGPRSGQNHRFASEPKGGLTSLTEPHPGPGFKCRSDLMQKYEKLEKIGE GTYGTVFKAKNRESHEVVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHS EKKLTLVFEYCDQDLKKYFDSCNGEIDPDTVKSFMYQLLRGLGFCHSHNVLHRDLKPQNL LINKNGDLKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIF AELANAG----------------------------------------------------- ------------------------------------------KYLTNEGPRSDVRYPLKG EC-SLPLEYCEYNPNYDNCKEWMKKNLPEEMLAMLLKRQTRGGRGKVKAKKKSEPKQICL STAPRGKKKYVTVITGLATYDIDLKKASKHFASRFSCGSSVTGNDEIVIQGDVKD----- ---------------------SYCSDRSATWCQMREALCGTLEARKSLLSGTPETWSRYY FYPTSPGGLNAVSPFGYSGVYVPNKETLVTDAGKLYVLDTLLARLKAEDHRVLIYSQMTK VIDILEEYMWHRKHTYMRLDGSSKISDRRDMVADFQSKSDIFVFLLSTRAGGLGINLTAA DTVIFYDSDWNPTVDQQAMDRAHRLGQTKQVTVYRLICKGTIEERILQRAKEKSEIQRMV ISGGNFRPDVLKPKEVVSLLLDDDEMERKMSLGTVPKELRNLRACLLCSLIKTFEQFEFD GCDNCEEYLHMKNNRDAVYDCTSSSFDGLLSMMSPEDSWVSKWQRINRFNKGCYAVSVTG RLPPGIVRELKSKGIIYRARDTSMPRYTQYLTKEQEDELRKIANAIVAPGKGILAADEST GTMGKRFAQINVDNTEENRRQYRQLLFTSAADHISGVILFHETFYQKADDGTPFVKMLQD NGIIPGIKVDKGVVALGGTDNETTTQGLDGLAERCAQYKKDGAGFCKWRCVLKIQSHTPS YLAMVENANVLARYATICQQNGLVPIVEPEVLPDGDHDLETAQRVTEEVLAFQYKALQDH HVFLEGTLLKPNMVTAGHSCPKKYTPEEVAKATVTALQRTVPAAVPGITFLSGGQSEEDA TIHLDAINKKPWSLSFSYGRALQASVLQAWKGKKDCVAAGQEELKKRAKSNGLAAMGQYG GGTGGAGGQSLFVADHRYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIILLK EGTDSSQGKPQLISNINACSAIVDAVRTTLGPRGMDKLIVDNNGKATISNDGATIMKLLD VVHPAAKTLVDIAKSQDAEVGDGTTSVVLLAGEFLKQSKPYVEEGVHPQIIVRAFRKATY LAVQKIKEIAVRIPKDAAKHKGLLLKCAATALSSKLVAHQKDFFASMVVDAVMSLDELLP LNMIGIKKVQGGALEESQLIAGVAFKKTFSYAGFEMQPKKYLNPKIALLNIELELKAEKD NAEIRVDSVEEYQSIVDAEWTILYSKLGKIYNSGAKVVLSKLPIGDVATQYFADRDLFCA GRVTEEDLKRTMKACGGSIQTTVANISLGTCELFEEQQVGGERYNVFKGCTRAKTCTLIL RGGSEQFIEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRNYSRTIPGKEQLL IGAMAKALEIIPRQLCDNAGFDATNILNKLRQKHAGTWYGVDITIEDIADNFEACVWEPA IVKINALTAASEATCLILSVDETIKNPKAEGGPPGAGRGRGRPM---------------- ----------------------------------------------------------IR DWSVTGVPKKEAKTIGISVDFRRRNKSVESLQINVQRLKEYRSKLIIFPKKASNPKSSDA TEEEMKMATQVRY-VMPIRTAFKPEKARAPTDEE-------------------------- ---MPNIKIFSGTSHPDLAQKIADRLGIELGKVVTKKFSNQETCVEIGESVRGEDVYIVQ SGCGEVND---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------VMVNVRSIAEMGAYVHLLEYNNIEG MILLSELSRRRIRSINKLIRVGRSECVVVIRVDKEKGYIDLSKRRVSQEEVMKCEEKFAK AKAVNSILRHVGEILGYESNEQLEDLYTQTAW---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FENKHPKSELPAELKEV---------------------------- ---------------------------------------------QQQQHMTCKGCGMLV AGVFVKIKGEPYHPECFKCAACGKNLKQQGYFQISGQLYCEVDARQMAQP---------- ------------------------------------------------------------ ----------------------------------------------XXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXANERKLFVGGNWKMN GNKQSIDGIIKFLNEGNPNTDVVVAPPALYIDYVRQNLIGVAAQNCYKAEKGAFTGDISP AMIKDVGVEWVILGHSERRHVFGESDQLVGEKVAHALAAGLHLIPCVGEKLDEREAGKTD EVVFRQTKASDWSRVVIAYEPVWAIGTGKTATPDQAQEIHNKLRNWFKDNVSADVASKVR ILYGGSVSAANCKELAKKPDIDGFLVGGASLKPDFNQIINAREREGLLDPAWEKQQRKTF TAWCNSHLRKAGTQIESIEDDFRNGLKLMLLLEVISGEQLPKPDRGKMRFHKIANVNKAL QFIESKGVRLVSIGAEEIVDGNVKMTLGMIWTII-------------------------- ------------------------------------------------------------ -------------XLKVNQENERLMEEYERMASDLLEWIRRTTPWLENRTTDNTLPGTQR KLEEFRDYRREHKPPKLEEKAKLETTFNTLQTRLRLSNRPAYMPTEGKMVSDIASAWKGL EFAEKGFEEWLLSEMQRLERLDHLAQKFKHKCAIHEEWAFGKEDMLQSQDFKQCKLNELK ALKKKHEAFESDLAAHQDRVEQIAAIAQELNALDYHDVVTVNARCQRICDQWDLLGTLTQ SRRNALDEAEKILERIDQLHLEFAKRAAPFNNWMDGAKEDLVDMFIVHTTEEIQGLIDAH EQFKQTLGEADKEFNSIIQLVQEVTRIAQQYGIMGGSENPYTTLSAQDIAHKWTEVKQLV PQRDSVLQQEMLRQQNNERLRRQFAQKANVVGQWIERHLDAVASVGMGRGSLEEQLNKLN AMEKEVMSYKPNIDELERFNQEVQESMIFENRHTQYTMETLRVGWEQLLTSVARNINEVE NQILTRDSKGITNEQMDEFRKSFNHFDKGRTRRLEPKEFKACLVSLGYNIRDDRQGEADF QRIMSIVDTNHTGYVTFDAFLDFMTRETTDTDTAEQVMQSFKILAGDKAYITAEILRREL PPDQAEYCIQRMAPYTGRDGEHGALDYMSFSTALYGESDLNKLSIDSLNLKGQRVLIRVD FNVPLKEGSITNNQRIVAALPTIKHALDNGATSVVLMSHLGRPDGQPNEKFSLKPVADEL KKLLARDVQFLSDCVGADVEAACANPATGSVILLENLRFHPEEEGKGVDKEGKKVKASPE AVEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGCQLPQKASGFLLKKELTYFSKALDNPV RPFLAILGGAKVKDKIQLIENMLDRVNEMIIGGGMAYTFLKVLHGMEIGNSLYDEEGAQI VNKLMEKAEKNGVQIHLPTDFVNGDKFAEDAQVGKSTISEGIPAGWMGLDCGQETVTKFT EAIGRAKTIVWNGPAGVFEFENFAHGTKAVMDAVVTATEKRTTTIIGGGDTATCCAIWKT EDKVSHVSTGGGASLELLEGKTLPGVAALSEAMAGIPPKTWQPSNVTLETTLGTIVCELY WKQAPNSCRNFAELARRGYFNDIKFHRIIKDFMIQTGDPTATGRGGASIYGKQFDDEISN ELKHTGAGILSMANSGPDTNGSQFFITLAPTQWLDGKHTIFGRICSGMIVVDKVGKVETD TSDRPIEDIKM-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXFIPLFDRVLVQRFAAETKTKAGILIPEKAQGKVLEATIVAIGPGSR TDKGDLVAPSVKVGDHVMLPEYGGTKVTLEDKEYFLFRDGDILGKFEXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMADEALSRHGLHFDELNK IRVLEPEVSQQTSELKEECKDFVDKISEFQKIVGGFIDVIDSVSKEVEKEKMKAIGSRNL LKSIAKQREAQQQELQALITEKKMQLERLRIQFESLQKEESEQNEFIEQFILQK------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------NKHGGALHIYVDKAS PQGNVYVKCPSISAAVASVQALHGRWFAGKIITAAYVPLPNYHQLFPDALRTVQLLMPST -ERDEDVSP-PPHPPKRRPRRGAVSAEVYTEEDAASYVKKVVPKDYKTMAGLSKAISKNV LFAPLDDNERSDIFDAMFPI---------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------DRQRFERVLGPCGDILKRNIQQYNSF VSLSVVSYKGLAKLNRLLYIADHAHTYVMTTYNTNVYQQVHRKLHEAVASNVPGLDTQWI ETTAKKAAMKLEKLDTDLKNYKSNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDY CTSAKHVVNMCLNVIKVSVYLQNWSHVLSYVNKAEVTP---EGKDGGQAVITKLKCAAGL AELATKKYKSAAKYFLQASFDHCDFPELLSPNNVATYGALCALASFDRQELQKNIISSSS FKLFLELEPQL---------------------IKDNLVLDMYLCQHVNTLYTQIRNRALC QYFSPYLSADMNKMALAFNTTVTSLEDELMQLILDGQINARIDSHNKILYAKDIDQRSST FEKSLVMGKEYQR----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------KTKLCALILVGWLTIINIYFNAWWNIPANRPMRDFLKYDFFQTLSVV GGLLLVVALGPGGYSMDEHKKKW------------------------------------- ------------------------------------------------------------ ----------------LKIVTKEKSKRIAKFAFDYATKHGRNKVTAVHKANIMKLGDGLF LDSCREVSELYPKLEFESVIVDNCCMQLVSNPYQFDVMVMPNPYGNIVDNLASGLVGGAG VVPGESYSHDVAVFEPGARHPFAQAVGRDIANPTAMLLSASNML---------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------KKSSPEYIFHCQSAVMSSCFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPA QRTPLSAAAHTHPVYCVNVVGTQNAHNLISVSTDGKMCSWSLDMLSAPQDSMELQHKQSK VAVTSMSFLSGDVNNFVVGSEEGAVYTACRHGSKAGIADMFEGHQGPVTGIDSHTVPGQI DFSHYFLTSSFDWTIKLWNMKDNKPLHSFEDNSDYVYDVKWSPIHPSLFASVDGMGRLDL WNLNHDIEVPIASSYNVSLNRCRWHQTGHQIAVGDDLGKIHIYDVGEHVANPRSDDWNKF VHTLQDIRNNQNDQDDD------------------------------------------- ------------------------------------------------------------ --HVETRFVKINAEKCPFLTERLRIVVIPTICLAKAGKTVDYVVGFDDLGGHDEFHTDIL EWRIARADVINYSGDLMTPPTTG------------------------------------- ----------GLNFAELMARQGMYDFSMKTPCVLGLEGAGEVIEIGDGVDQVKIGDRVVM MNGLWTEAAVRVFKIPDKMTFEEAAAIPVNYITAYHMLFDFGNLRKGKSVLIHMAAGGVG VAATQLCQMVEDVTIFGTASAKHEFLIKSGLTHPIDYRTKDYVEEIRKISPKGVDIVLDP LSGADSVKGFNLLKPMGKIIHFGAANAVTGEKRKQYK----------------------- ---------FIDVALPHFQSGKLRTVVDKVFPLDKISEAHQFMEDNKNIGKIVLKVREMS RKQTPSDFLKQIIGRPVVVKLNSGVDYRGVLACLDGYMNIALEQTEEYVNGQLKNKYGDA FIRGNNVLYISTQSRR-----------KKQLGELNKNPVDGFSAGLIDDEDIYRWEVLII GPQDTLYEGGFFKAHLTFPKEYPQKPPKLKVISDIWHPNIDKSGDVCISILHDPGEDKYG YERPEERWLPIHTVETIMVSVISMLTDPNSESPANLDAAKEYRENQDVFKKE-------- ---TVVPQNPVMKQQLSDFGKYVGECLPKYVQKVQVTAFHELELLIHPDGVIPVISFLKD NHSGQFLSLADIAGMDVPSRKYRFEVIYNLLSLRYNQRIRVRTYTDELSPIDSICSIYHG ANWYEREIWDMYGVFFANHPDLRRILTDYGFEGHPFRRDFPLSGYTEVRYDDEVKRVVIE PIELSQEFRKFELGNPWETFPAHRQ----------------------------------- ----------------------CNPPVYLILLDTCMEEEDLQAVKESLQMSLSLLPPNAL IGLITFGRMVQVHELGCEGCSKSYVFRGTKDLTAKQIQDMLGIGRGMTQLPSNRFLQPVH KCDMALTDLLSELQSDPWPVAQGKRPLRSTGVALSIAVG--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------NISDTEIGVGGTSQWKMCGVYPNSTYGFYFEVVNQHNAPIPQGG RGYVQFITQYQHSSGQKRVRVTTVARNWVDG-------------EAAAVLMARIGIHRAE TDDGPDVLRWLDRMLIRLCQKFGDFHKDDPNSFRFSDQFSLYPQFMFHLRRSPFLQVFNN SPDESSYYRQMLNHEDLTQSLIMVQPILYAYSFSGPPEPVLLDTSSI------------- --------------------------------------EIIQTRFPMPRYIDTEAGGSQA RFLLSKVNPSQTHNNMYSEGGGHVLTDDVSLQVFMDHLKKLAVSSASXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------VTEEEGGKNAITFVQSLLDLKDRFDHFL HESFSDDKQFKKMVSGDFEYFINLNQKSPEYLSLFIDDKLKKGVKGMTEQEIENVLDKSM VLFRFLQEKDVFERYYKQHLAKRLLLNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFKD MTVSNTTMEEFKTHVQQGTNLYGVDLFVRVLTTGFWPTQSATPKCNIP-----------R FYLAKHSGRQLTLQPQLGSADLNATFYGAKKEDGDSKTGSRKHIIQVSTYQMVILMLFNN RDRLTYEEVKNETDIPERDLMRAVVSTQSGHYGR-------------------------- -------------------------------------------------EHNILIAEATE QLKSRFLPSPVIIKKRIEGLIEREYLARTPEDRKIYTYVAXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXX-LRVLVTGAAGQIAYSLLYSVAKGDVFGANTPISLVL LDIAPMMTVLEGVVMELMDCALPLLQKIVPTADEAVAFKDIDVAILVGAMPRREGMERKD LLAANVKIFMSQGKALDTYAKKTVKVVVVGNPANTNAFICKKYAPSIPKENITCLTRLDQ NRAQAQIAHRNDVSNVIIWGNHSSTQFPDVAHAKVVYEVVKDDHYLRNDFIKTVQQRGAA VIKARKLSSAMSAAKAIGDHMRSWWFGTEQGKFTSMGVVSDGYDIPEGILYSFPVKIDHS HEIVKGLKIDDFAKEKLQITLKELMDEKEMAEAACGGTSGVLMVGPNFRVGKKIGCGNFG ELRLGKNLYNNEHVAIKLEPMKSRAPQLHLEYRFYKQLGQAEGVPQVYYFGPCGKYNALV LELLGPSLEDLFDLCDRKFSLKTVLMVAIQLITRMEYVHSKHLIYRDVKPENFLIGRQSN KKQHIIHIIDFGLAKEYIDPETHKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEAL GHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEELAQYLRYVRRLD FFETPDYDYLRKLFHDLMDKKGWDCDWQ--------RHGGSVQVVSSANGELAPTAGHSN TPITTPAEVEVVDETKC-MTTLRPFTCDDMFRFNNVNLDPLTETYGLPFYMQYLAHWPEY FQIAESPSGEIMGYIMGKAEGHSDNWHGHVTALTVAPSYRRLGLAAKLMNILEEISEKKR CFFVDLFVRVSNKVAVDMYTRLGYSVYRRVLEYYSGEVDEDAFDMRKALSRDVEKKSVIP LTHPVRPEDLDQQLDCALDLMRRLPPQQIEKNLSDLIDLVPSLCEDLLSSVDQPLKIARD KTTGKDYLLCDYNRDGDSYRSPWSNTYEPPLDDGAVPSDRLRKLEVEANHAFDLYREMYF EGGVSSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRSAHYKLTST AMLWLQTNKTGSGTMNLGGSLTRQIEQDATVSESSPHVVNIGRMVEDMEFKIRNTLNEIY FGKTKDIVNGLRSTLSLQQDIIQRDLQAALAKRGQFDDDLDDVDEPLDEVENGERIDVLP S-ERVDPSKRITTPFMTKYERARVLGTRALQIAMCA------------------------ --------------------------DKLTIGEKARAPAGDTAFSLGRGAVAGASVLGIG ALCYYGLGMSNQMGAVDRAVLWPEVVRMRIRDTYMYFGGGIVVTAVARNPALMRMMTKQS WLAIGATFAAMIGSGMVCRSIQYKPGAKQLAWMAHAGIVGAVIAPLAFLGGPILIRAAWY TAGVVGGLSTLAMCAPSEKFLNMGAPLTMGLAVVFASSIGGMFFPPTTALGAGLYSMSIY GGLILFSMFLLYDTQKIIKRAETHPVYAVQPYDPVNASIGIYLDTINLFIRIAMILANGG GRKK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------KTTWIQSKTGTECFSASTDGQVLWWDIRKLG EPTEKLILDPTKKQDITKAQGAFALEYEPTIPTKFMVGTEQGSVLSCNRKAKTPQEKIVA VYPGHHGPIYALQRNPFFPKNFLTVGDWTARIWSEDIRESSIMWTKYHMAYLTDGCWSPV RPAVFYTTKMDGTLDIWDFIFKQNDPTLSIQVSDEALHSIRVQEQGRLIACGSQSGTTTL LELSDGLCTLQRNEKTLVTAMFERETRREKILDSRHREMKLKERTKSS----------IA NPLASKKLAKKLYKVIRKALRKGVKEVQKFVRKGEKGIVVLAGDTSPIDVICHMPFVCEE VGLPYCYTPSKEDLGAATGSTRPTCMVMIKTDDDYQELYDKCYSEVKGLPLPVMPVENLE EEGLEKNPNLELSQWKFLLTTDQYRNNEDIKKQLLAVIKSDNMAPFYEEVCTELGWKVDQ DWLKQMKETNEAELKKLDEAVEDAEKNLGETEVRDGMLKKGEYLVKIGSKEAALTQFRKT FEKTHTLGYKLDMVFHLIRMGLFYMDHDLITRNLEKAQSLIDEGGDWDRRNRLKVYRGTY NMAIRDFKSAANLFLDTVATFTSYELMDYKTFVTYTVLCSMIALERPNLKEKVVRGSEIL EVLHSLPDIRQYLFSLYNCQYADFFKSLAHVEQIMKTDRYLSSHFRYYNREMRVHVYAQL LESYRTLTLDYMAKAFGVSVGYIDQELSRFIAQGRLHCKIDKVGGIVETTRPDSKNWQYQ ATIKQGDVLLNRIQKLSRVINITRGLQTTAEKIAGIPYKNLSIGVPKELFQNERRVALAP ATVAILKKGFTVNIEENAGVLAKFANDDYAAGGANIAVNDVYKSDIILKVRAPLTEEVNR FNEGNTLYSFLYPAQNKELVDQLAARKLTAFAMDCVPRISRAQVFDALSSMANIAGYKGV LEAANNFGRFFTGQITAAGKTPPAKVLVIGAGVAGLSAIGTAKNMGAVVRAFDVRSSVKE QIQSMGAEFLEVNFKEEGEGTGGYAKEMSPEFIEAEMALFAKQAKECDIIVTTALIPGRP APKLIKKYMVDAMKPGSVVVDLAAEAGGNIETTRPGEVYTYNDVVHVGYTDLPSRLPTQS SSLYANNISKLLLSVGYNVDLEDEVVRGSIILHEGKMMWPPPKPPPPNYFNITLKDSLMY TAGLGTIAGLGIISPNPAFSTMMTTFGLAGIVGYHTVWGVSPSLHSPLMSVTNAISGITA AGGLLLMGGSSLPTSTAHILAATAAFISSINIGGGFLVTQRMLDMFKRPD---------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------TVDMITSAQNIIITPGYGMCVAKAQYPVAEIISTLRQKGINVR FGIHPVAGRMPGQLNVLLAEAGVPYDVVLEMDEINDDMPETDLVLVIGANDTVNSAAEED PNSIIAGMPVLRVWLSKQVVVMKRSLGVGYAAVDNPIFYKENTAMLLGDAKK-------- --MARPEVIPGCPPGLEYLTQIDQILVHQQVELFEAFTSWETSNRYQIKNSMGQQVYFAA EESDTCMRQCCGPQRGFTMHITDNLNQEVIRVSRPFKCCAGCNCCAFCAMEVEIEAPVGN TVGYVKQTCLAPKYEIQDAVLNIEGPVCICQ--CCTWDQEFKIFSQEIGKISKQWSGFVK EYFTKADNFGVSFPMDLDVKIKAVLLGAVFLIDFMFFE----KADAELQQFIAMETQKAQ FQKTIHELTDVCWEKCMDKPRDKLDYKTEGCMSNCVDRFVDTTLIITQRFQQLIQK---- ------------------------------------------------------------ ------------------------------------------------------------ LSGETWNPLKLKYQLRNVRERLAKNLVEKGVCTTEKQNFLLFDMTTHPLTDNTIKSKLVK KVQDAVLSRWVNDPQRMERRILSLLYLA-------------------------------- -----------------------QSRIDKVTEENCEVCVKFVARFINGLDKIEDAFKKQC KNTKKDDNRFCYYVGGLEESATGILGEMSRPISIGMPPEKVC------------------ ----------------KKILSDWEEQCRGCAEKSDYVKKVEELMPKYAPDAWXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXMPKVVSRSVVCTDTKDQEEYQGEKPLYVYYCICGQMSLILDCPID KLPLRRRDNARVIDAGKHAHKITADTDETVYLKRPGGIERQYRQKCKTCGLWLYYRHKAT VTFIIDGALKKSGEVRKDVYSQIAQPKKVTLTKHTKNMGKFSSVTVSTVDEEEEEIEAKE IADSYAANARVIEKQLLRK--------------------------XXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXX---------------------------------IKYKTSELRLTESLHDPHIC DRILEYNVHAERKGSLRYGKGRSETMETLHGLVHKGVKVELGIPYELWDKPSAEVTVMQR SCFKMVEDYEDDIEDWYY------------------------------------------ -FGRLDIAVNCAGIGVACKTYNFKKGIPHGLAEFQRVLNINASGTFNVTRLAVGLMGKND PNSDGQRGVVVNTASVAAYDGQIGQVAYAASKGAIVAMTLPMARDLASCGIRVNTIAPGL FDTPLLAQLPEKVRKFLASTVPFPQKLGLPDEYAHLVQSIVENPMMNGEVIRIDGAIRCR DFHFRVHGQNAESKGQISRDYPVVDHTYDAVVVGAGGAGLRAAFGLANEGFKTACITKLF PTRSHTVAAQGGINAALGHMEEDDWTYHFYDTVKGSDWLGDQDAIHYMTEEAPKAVLELE NYGMPFSRLENGKIYQRAFGGQSLKYGAGGQAHRCCAVADRTGHSLLHTLYGRSLYYDTT YFIEYFALDLIMEEGECRGVIALSLEDGTLHRFHSKNTVLATGGYGRTYFSCTSAHTCTG DGTAMATRAGLANEDMEFVQFHPTGIYGAGCLITEGCRGEGGYLLNSEGERFMERYAPNV KDLASRDVVSRSMTLEIREGRGVGPEKDHAYLQLSHLPLEQLKMRLPGIMETAMIFAGVD ATRDPIPVLPTVHYNMGGVPTNYKGQVIQMDGKDYLIPGLYACGEAACASVHGANRLGAN SLLDLVIFGRACALTITEENRPGDKIGPIKDNAGEESVANLDKLRYADGKTPTADLRLRM QKTNQNHAAVFRDGPTLKEGVDKMEKLYDEMDLKVSDRGMVWNSDLVETLELQNLMLNSM QTVVGAEARKESRGAHAREDFHERIDEYDYTKPLESQQKRPIDKHWRKHTLSYMNEDTGK VTLEYRPVIDHTLDKNKVDTIPPKIRVY-------------------------------- ---------------LVEEKTSILKKTIEMIELGLGEAQVMMALASHLQYVESEKQKLRA QVRRLCQENAWLRDELANTQQRLQHSEQRVATLEEEKKHLEFMNEMKKYDSD-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------RVQGKYDQDVEAECIAWIKQLLPPGMRNVEK ALRDGQALVELCLVIACNKLKLKVNKMNTAFKQMENIEVFLKFCHAYGIPKTLLFPTVDL YEGRNMSNVLAAIQLLGSEAQRHGFNGPTIGPKPTEKHVVEFTEEQLRAGSLQAGTNKCA SQSMGGVRHVADIKADDMSKDSAGYIGLQAGNKGASQKGMAIGAVRHVSDIRADDMSADS ASHIGLQAGSNKGASQKGMAIGAVRHVSDIRADDMAADSAGHIGLQAGSNKGASQTGMSM GAVRHVADIRADDMVKTS--IGLQMGSNKGASQKGMSMGAVRHVADIRADDA-DKSSIGL QMGSNKGASQAGMSMGAVRHVADIRADDMAGKGEINLQYQGSTGATQAGMSMGKQRRIMP EVHPFGIEPITCHAWNINRTQLAIPNNHEVHIYQFKWNKTHELTEHQQRVTGIDWAANSN RIVTCGADRNAYVWPTLVILRINRAATCVKWSPMENKFAVASGARVISVCYFEMENXXWL --------------------------------------XVKEIEDKPAATPWGKKMTFGN CMVEFSNGGGWVHCVSFSASGDKLAWVGHDASVSIVNATLKSQQLPFMSCLWLTENSLLV AGHGCVPMLFTHDGSQVTFVNKLE------------------------------------ ------------------------------------------------------------ -KSTLINSLFLSDMYSAEYPGPSLRIKKTVQVETTQVLLKEGGVQLRLTVVDTPGFGDAV DNSNCWQPVTDFIESRYDEYLNSESRVNRRTTADSRVHCCLYFLSPNGHGLKPLDVEFMK RLHDRVNIIPLIAKADTMTPDECRDFKKTILNEIAQHKIKIYEFDDEEEKKIQKKLKDRV PFAVVGSNTVVESQGKKIRGRMYPWGIVEVENLEHNDFIALRNMLIRTHMQDLKDVTNNA HYENFRYNKLATVTKNPIAQMEEEKQEHVTKMKKMEAEMEQVFE---------------- ------------------------------------------------------------ ------GHAGTCLGILATDGVVLSAERRNTNKLLDEVSNSEKIYKLNEDMACSVAGITSD ANVLTNELRLIAQRYMLQYQEPIPCEQLVTTLCDVKQAYTQFGGKRPFGVSILYMGWDKH YGFQLYQSDPSGNYGGWKATCIGNNSSAAVSMLKQEYKEGETSLKDALGLTIKVISKTLD TNKLTNEKVEIATLTRENGQTVIRILPANEVGALIKLHEEQEAKAEAEKKK--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -MLETEDYGKDLATVQNLVKKHQILDADVNAHEDRINDLNEQADEFIQSGMWDVESIKVK KTTINERYERVRTLTIERRSRLNEANTLHQFFRDIDDEEAWIKEKKLLVGSDDYGRDLTG VQNLRKKHKRLEAEISSHEPSIQAVQETGQKLMEDSSLMTEDIKQRLETLASNWEELKQM AVLRGQKLDESLVYQQFSANVEEEEVWITEKQHLLSGDDCGDTLAAVQGLLKKHDAFETD FQVHQDRCHEVNKEGEKLISEGNHNADAIGQRCATLQEKLTALQQAANRRKSSLIDNSAF LQFIWKTDVVESWIADKETQVRSEDYGRDLSSVQTLLTKQETFDAGLQAFEKEGIQTITA LKEQLVASNHAQTKAIEARYAAVIERWQKLLADSDARKQRLLKLQEQYRQVEDLYLTFAK KASAFNSWFENAEEDLTDPVRCNSVEEIMALREAHEQFKASLSAAETDFNQLAALDRQIK SFNVGPNPYTWFTMEALDDTWKNLQKIIRERDAELGREQQRQEENDVLRKEFAQAANAFH GWLTETRAAMMEGSGTLESQLEATKRKAAEVRAQRGQLKHIEDLGAAMEERLILDNRYTE HSTVGLAQQWDQLDQLGMRMQHNLEQQIQACNTCGVSEDALREFSMMFKHFDKDKSGKLD HYEFKSCLRALGYDLPMVEEGQQDPEFEAILDSVDPNRDGFVSLQEYIAFMISRETENVQ SAKDVEAAFRALTSGDKPFITANELYANLTKEQADYCVRRMKPYEDPKGRVIPDAYDYST FTRTIFVN---------------------------------------------------- -----------GSRSETGVAWGCRWEWEENGVWKENCYCEDQDGCNSSTH---------- -------------------EINGRMRGILIDWLVQVHLRFHLLQETLYLTVAIIDRFLQE EVTRNKLQLVGVTSMLIASKYEEMYAPEIGDFEYITDNAYQKKDIRTMECLILRTLEFNL GRPLPLHFLRRNSK----------LAKYLMELTIVDYDMIHIPPSEIAAAALCLSMKILD WSDTLNYYSKYSEKDLMPIMKKMAGLVLKKLTAIHTKYKSSKFMRISVIPELQS------ -XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--ALSVGG DRTTGQSVRTQNVMAACSIANIVKSSLGPVGLDKMLVDDIGDVTVTNDGATILQLLDVEH PAAKVLVELAELQDQEVGDGTTSVVIIAAELLKNADELVKCKIHPTSIISGYRLACKEAC KYIQEHMTIGTDDLGRECIINAAKTSMSSKIIGPDSDFFSNMVVDAAYAVKTADGKGGHR YPIKAVNVLKAHGKSTRESILVHGYALNCTVAAQGMPKKVVNAKIACLDFSLQKAKMKLG VQVLVEDPGKLDAIRQREYDITKERIQKILSAGANVILTTGGIDDLCLKYFMEAGAMAVR RCKKVDLKRIAKATGGTLVLTMANLEGEETFEASLLGQADEVVQERICDDELILIKGPKA RTAASILLRGANDFMVDEMERSVHDALCVVKRVLESKTVVPGGGAVEAALSIYLENYATS LSSREQLAIAEFASSLLVIPKQLAVNAAQDSTDLVAKLRAYHNKSQTKAEHKDLKWVGLD LYEGIVRDSKKAGVFEPAISKIKSLKFATEAAITILRIDDMI------------------ ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------- -------VEGLRAFVEAMVNENVSLVISRQLLTDFSGHLAKLPDTTSKDVSHFTLEKIQP RVISFEEQVAFIRQHLAGIYEREQSWREAASVLVGIPLETGQKQYSSDYKLETYLKIARL YLEDEDPVQAEAYINRASLLQADSQNEELQIYYKVCYARVLDYRRKFIEAAQRYNELSYK AIVAEDERMHALKNALICTVLASAGQQRSRMLATLFKDERCQQLPAYAILEKMYLDRIIR SSDLQEFSALLLQHQKALTSDGSTILDRAVIEHNLLSASKLYNNISFEELGALLEIPPAK AEKIASQMITEERMNGHIDQIVHFVHFEVREALPSWDKQIQGLCFQVNNIIEKISQHSP- -----------MKLTDLVVRSYRVAKVFRENNEKINSIDFSSNGETLITSSDDDSIVIYD CQNGTPKRTLNSKKYGVDLIHYTHAANTAVHSSTKIDDTIRYLSLHDNKYIRYFQGHTKK VVSLSMSPIDDTFLSGSLDKSIRLWDLRSSNCQGLMHLTGRPVAAFDPEGLIFAAGINSE SLKLYDLRSFDKGPFATFRLQQDKDCDWTGLKFSPDGKLILISTNGQVIRLIDAFQGAPL QTFMGHTNKGGIPLEASFSPDSQFVFCGSTDGKVHMWNTETGAKVAILASEHTSPIQCIQ FNPKYMMLASACTNMSFWLPQIDEEHLLVEKRGQKNNVGYIQLNRPKALNALCDGLMKEL AEVLETFEADKEIGCIVLTGSEKAFAAGADIKEMKDRKFQEVFGGNFLNHWNRLALTKKP VIAAVNGYALGGGCEIAMMCDIIYAGEKAKFGQPEIALGTIPGAGGTQRLTHAIGKSRAM EMVLTGNPITAQEAANTGLVSKVFPVGDLVNEAVKTAEKISSQSKLVAAMAKEAVSASYE LTLQEGLRFEKRIFHATFATEDRKEGMAAFSEKRPANFVD >Phylo_foetida MSDRKAVIKNADMSEEMQADGVDCATQALEKYNIEKDIAAYIK----KXYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSGFNSQVRQFQTSSIQRDIDQAAKYIGAGAATV GVAGSGAGIGSVFGSLVIGYARNPSLKQQLFTYAILGFALSEAMGLFCLMMAFLILFAFX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMDQVM QVVEPAKTFAKDSIRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVK---------- -XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSKRGRGGS AGGKFRISLALPVGAVINCADNTGAKNLYVIAVSGIKGRLNRLPAAGSGDMIVATVKKGK PELRKKVMPAVVIRQRKSIRRKDGLFIYFEDNAGVIVNNKGEMKGSAITGPVAKECADLW PRIASNASSIRKGRVQKVSLGPQTVEGENVFGVAHIYASFNDTFVHVTDLSGKETIVRVT GGMKVKADRDEASPYAAMLAAQDVAERCKVLGINALHIKLRATGGNKTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRLMGKPRGLRTARKIRNHRREQKWHDKD YKKSHLGTRWKANPFAGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP RDGCLNYIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANTSLLALYKEKKERPRSDSV VTLRTRRFLTNKLLARKQMVVDVLHPGTATVKKTEIREKLARMYKTTADVVFCFGFKTQF GGGKTTGFALIYETLDFAKKFEPKYRLQRHGSRKQRKERKNRQKKVRGTKKAKVGTMGRV PLVNSKTYTTPRRPFEKERLDQELKIIGQFGLRNKREVWRVKYTLAKIRKAARELLTLEE KDSRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLRAEDFLERRLQTQVFKLGLAKSIHH ARVLIRQKHIRVRKQVVNIPSYVVRLDSQKHIDFSLKSPYGGGRPGRVKRKNAKKGQAGA GDMGNIFQSLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVGEAREELMRMLAEDELRD AVLLVFANKQDLPNAMNAAEITDKLGLHSLRQRNWYIQATCATSGDGLYEGLDWLSNQLK NQK-PLAKDLLHPTVEEERRKCKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCI GCSTVLCQPTGGKARLTEGCSFRRKQHMVRMNVLADALKTLCNAEKRGKRQVLIRPSSKV IVRFLTVMMKHGYIGEFEIIDDHRSGKIVVNLTGRMNKCGVISPRFDVGVRDLETWTIRL LPSRQFGFIVLTTSGGIMDHEEARRKHLGGKILGFFFMGRMHAPGKGISQSALPYRRSVP TWLKLTPDDVKEHIYKLAKKGLRPSQIGVILRDSHGVAQVRFVTGNKILRILKAKGLAPE LPEDLYNMIKKAVAIRKHLERNRKDKDSKFRLILNEARIHRLARYYKKRKVLAPNWKYDS ATASALVAVAELPEIKLFGRWSTEDVQVSDISLTDYVAVKEKYAKYLPHSAGRYQVKRFR KAQCPIVERLTCALMMHGRNNGKKLMAGRIVKHSFEIIHLLTGDNPLQVVVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREASFRNIKTIAECLSDELINAAK GSSNSYAIKKKDELERVAKSNRMTEQMTLRGTLHGHGGWVTQIATTPQYPDMILSASRDK TLIMWKLTRDTNYGIPQKSLHGHGHFVSDVVMSSDGQFALSGSWDGTLRLWDLGTGQTTR RFVGHTKDVLSVAFSADNRQIVSGARDKTIKLWNTLGVCKYTIEDGHSEWVSCVRFSPNT QNPIIVSAGWDKLVKVWNLTNCKLKTNHYGHTGYLNCVTVSPDGSLCASGGKDGQAMLWD LNEGKHLYTLDGGDIINALTFSPNRYWLCAATGPSIKIWDLEGKVVVDELRQEVISKS-E PPQCVSLAWSADGQTLFAGYTDNLIRVWQVSMAA-MREYKLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKVVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKLARSWNCAFLETSAKSR INVNEIFYDLVRQINRKNPESMSEEKKNSSEHINLKVTGQDGSVVHFKIKKNTPLRKLMS AYCERTGVKMESMRFRFDGQPINETDTPLQLDMEDGDSIDVFQQQTGG--AMPVNPKPFL NGLTGKPVMVKLKWGMEYKGYLVSVDGYMNLQLANTEEYIDGALTGSLGEVLIRCNNVLY IRGVEEDDEEGEMREMSDAEGDDVPS--APAGDMDINTALQEVMKTALIHDGLVRGLREC AKALDKRQAHMCILANNCDEPAYVKLVEALCAEHGINLLKVEDNKKLGEWAGLCKIDKEG KARKVVGCSCVVIKDYGKESPALDYLNEYFKSKR-------------------------- ----------------VVSDKVISKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSI DSPDSLENIPEKWTPEVRHFCPNVPIILVGNKKDLRNDPNTIRELAKMKQEPVKPEEGRA MQEKINAFAYLECSAKTKEGVREVFETATRAALQVKKKKKSKMDDFQSAEETAFVVDEVS NIIKESVEAAIGGNAYQHNKVNQWTSAVVEQCLNQLSKLGKPFKYIVTCVIMQKNGAGLH TASSCFWDNTTDGSCTVRWENKTMYCIVSVFGLAIXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXERGGFRGGFGGR GRGRGRGRGRGKD-DKEWIPVTKLGRLVKDAKIRTLEEIYLFSLPIKEFEIIDFFLGTAL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDFNGHIGLGVKCSKEVATAIRGAIILAKLSV VPVRRGYWGNKIGKPHTVPCKVTGKCGSVIVRLIPAPRGTGIVSAPVPKKLLNMAGIDDC YTSATGQTATLGNFAKATYAAISHTYKYLTPDLWKDTVFQKSPYQEFTDHLTKMSGGLEV LGLKEEDVTKFLACGTHLGSTNVDYQMEQYVYKRKPDGVYILNLKKTWEKLLLAARAIAA IENPADVCVISARPYGQRAVLKFASYTGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDP RTDHQPVTEASYVNIPVIALCNTDSPLKFVDIAIPSNNKGVHSIGLMWWLLSREVLRLRG TISREVPWEVMVDLFFYRDPEEAEKEQEVADWGSEAVVPAVPTTTEDWGA-QTDDWGAAA T------MKFNKLVTSSRRKNRCRHFNAPSHVRRKIMSSPLSKELRTKYSVRSIPIRKDD EVQVVRGHYRGPQVGKVVQVYRKKFVIHIERIQREKANGASVHVGIHPSKVVVVKLKLDK DRKRILEQKAKSRKTGKHTEESIAPASSTSVGTTVRQRRAPASGAGAAGMWRFYTEDSPG IKVGPVPVLVMSLLFIASVFMLHIWGKYTRGXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXX--KSEFLVNGKYRLVRKIGSGSFGDIYLGINI SNGEEVAVKLESHKARHPQLLYESKLYKILQGGVGIPHIRWYGEKDYNVLVMDLLGPSLE DLFNFCSRRFTMKTVLMLADQMIGRIEFVHNKNFIHRDIKPDNFLMGIGRHCNKVFLIDF GLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQS-RDDMESLGYVLMYFNRGS LPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLR QLFRILFRTLNHQYDYTFDWTMLKKKAA--MNAEKLKQRIGGKGTARRKKKVVHRTATTD DKKLQTSLKKLGVNNIPGIEEVNMIKEDGTVIHFLNPKVQASLSANTFAVTGQAETKRIA DMLPGILNQLGGDSLASLKKLATAVDAIDEDDDDVPELVDNFDEPSKSEMVRYSLEAENV TKSAKARGSHLRVHFKNTRETANAIKKMHLRRAVRFLKNVTEKKECVPFKRYNGAVGRCA QAKNWGTTQGRWPKKSAEFLLQLLKNAESNADFKGLDTDHLVIEHVQVNRAPKMRRRTYR AHGRINPYMSSPCHIEVILSEREQAIARSKKKKVSQKKLKRQKMMMRDKKTGPKPELTEE QKQEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGTIDFND FLSIMTQKMAEKDSKEEILKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQEADRD GDGEINETEFLRIMKKTSLYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXDSGTDSDS-DSTPELEEVANAAGLSEEPVSKAKQSRSEKKA RKAMSKLGLKQITGVNRVTIRKSKNILFVVNRPDVYKSPASDTYIVFGEAKIEDLSQQAQ MAAAEKFKAEEEVDDTGVEPKDIELVMSQANVSRNKAIRALRNNNNDIVNAIMMGRVRTK TIKKASKVIIEKYYTRLTNDFHTNKRICEEIAIIPSKKLRNKISGFVTHLMKRIQRGPVR GISIKLQEEERERRDNFVPEISAIEEVDPDTKEMLKSLDFGNIPNLQVTQPI---MKWQY KEEHTFEKRKQEGEKIRKKYPDRVPVIVEKAPKARVGDLDKKKYLVPSDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGSLYQEHHEDDFFLYIAYSDESVYGXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AFYRQNLPNLMNLLATIFVFAVVIYFQGFR VDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLATKFSGNFFVNLLG VWADVGGGGPARSYPVGGLCYYLSPPETLSHVGEDPIHAMMYIIFMLGSCAFFSKTWIEV SGSSAKDVAKQLKEQQMVMRGFRDKSMVHELNRYIPT----------------------- ----------------------------------QTERAFQKQPGIFLNKKSALVLRYVK NVGLGFKTPREAIDGTYIDKKCPFTGNVSIRGRILSGVVIKMKMQRTIVVRRDYLHYIKK YNRFEKRHKNMSVHCSPCFRDLALGDIVTVGECRPLSKTVRFNVLKVTKSGQSKKGFVKF MVNVPKTRRTFCKGSKCRKHTLHKVTQYKKGKNSDYAQGKRRYDRKQSGYGGQTKAVFHK KAKTTKKIVLKMECTECKYKKQMPIKRCKHFELGGDKKKKGQMIQFMGRVIRSQRKGRGS VFRCHNKHRKGKPELRAIDYAERQGYIKGVIKDIIHDPGRGAPLAKVTFRDPYRYKQRTQ LFVAAEGMYTGQFVYCGKKATLQVGNILPVSSMPEGTIVCMLEHKTGDRGRLARASGCYA TVISHNQDTKRSRVRLPSGSKKVVPSANRGMVGVVAGGGRIDKPMLKAGRAYWKYKAKRN CWPRVRGVAMNPVEHPHGGGNHQHIGKASTVRRDTSAGRKVGLIAARRTGRLRGTKQIIQ KAKRTKKVGIVGKYGTRYGASLRKNIKKIEISQHSKYTCSFCGKETMKRRAVGIWACKSC KKIVAGGAYVFSTTAAATVRSAVRRLREMKEMGRRPARCYRYCKNKPYPKSRFCRGVPDP KIRIFDLGRKKARVDDFPLCVHLVSDEFEQLSSEALEAGRICANKYLVKNCGKDAFHLRV RLHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVKIGQTIMSVRAREGHKESCI EALRRAKFKYPGRQKIYVSKKWGFTPYDRSDYEEMRADGRLVPDGVNAKFMKEQGPLQKW M---KVTKVLGRTGSQGQCTQVRVEFLDDSNRSIIRNVKGPVREGDILTLLESEREARRL RMTKGTSSFGKRHNKTHTLCRRCGRSSYHIQKKRCAQCGYPSKRLRSFNWSEKGKRRKTT GTGRMRHLKNVHRRFRNGFREG--------MVDDRAAAKELDQWIEQLNDCKQLTENQVK TLCEKAKEILTKESNVQEVKCPVTVCGDVHGQFHDLMELFKIGGRSPDTNYLFMGDYVDR GYYSVETVTLLVALKVRFKDRITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDSQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHSNGLTLVARAHQLVMEGYNWCHDRNVVTIFSAPNYCYRC GNQAAIMELDDALKYSFLQFDPAPRRGEPHVTRRTPDYFLMGAYKYMQELYRRKQSDVMR FLMRVRTWQYRQLSSVHRAPRPTRPDKARRIGYRAKQGYVIYRVRVRRGGRKKPVRKGAT YGKPTNMGVNQIKNSRSHQAIAEGRAGRLLQGLRVLSSYWVGQDSMYKYYEIIMLDPHHK AIRRDPKINWICAANKKHRELRGLTSANRKSRGLGKGHTYTKTIGGSRRINWKRRNTLQM RRKRGIALGRLAEERKAWRKDHPFGFVARPTRNADGTLNLMNWECAIPGKKGTPWEGGLY KLRMLFKDDYPSSPPKCKYEPPLFHPNVYPSGTVCLSLLDEEKDWRPAVTIKQILLGIQE LLNEPNIKDPAQAEAYTIYCQNKLEYERRVREQAMRFRDPSL-KSSKMLQHINFRMRCTL QDGRVFVGTFKAFDKHMNLILGDCDEFRKVRPKSSKPREEKRVLGLVLLRGENLVSMTVE GPPPADEGIARVPLPGASGGPGMGRAAGRGIQHGQGLQGPVQGIGGPSQQHMRPQ--MGR AGPPQEVATFKLVLVGDGGVGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTTRGPIKF NVWDTAGQEKFGGLRDGYYIQGQCAIIMFDVTARITYKNVPNWHRDLVRVCENIPIVLCG NKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPA LAPPEVHMDPTMARQYEEELKRAQETALPDDDDELTEGIRPYYVSKIEELQLVVTEKTQN LRRLEAQRNELNAKVRMLREELQLLQEQGSYVGEVVKPMDKKKVLVKVHPEGKFVVDLDK NIDINDVTPNSRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEI KEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ KFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRLEGGSGGDSEVQRTMLELLNQLD GFEPKQNIKVIMATNRIDILDPALLRPGRIDRKIEFPAPNEEARLDILKIHSRKMNLTRG INLRKIAEMMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFELAVAKVMQKDSEKNISI KKQWKLSFAENFGLSGAAAIISKTAAAPIERVKLLVQNQDEMIKAGRLDKPYTGVIDCTA RTFRTEGVLPFWRGNLANCIRYFPTQALNFAFKDQIKILFKQKKEDGYAINFGKNIASGG TAGAMSLCFVYSLDYARTRLANDAKAGKKRQFNGLIDVYRKTLKSDGFVGLYRGFVISCV GIVVYRGCYFGFYDTLKPIVLGENAGLAASFVLGYVVTITSGLISYPIDTIRRRMMMTSG EAVKYKGSMDCARVIIRTEGFMSMMKGAGANILRGVAGAGVLAGFDKFKEVYISWRL--- -ADIDEWVEIAKECKYLPENSLKKLCDYVSELLLEESNIQPVSTPVTVCGDIHGQFYDLM ELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTLLLCLKARWPDKITLLRGNHESRQITQV YGFYDECQTKYGNANAWRYCCKVFDLLTIAAIIDECILCVHGGLSPDIKTLDQIRTIERN QEIPHKGAFCDLVWSDPEDVDTWAISPRGA---------------------CRAHQLVME GYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLRRDFTIFEAAPQEVRGKPQPDYFL VRLPPEVNRILYVRNLPYKITAEEMYDIFGKYGPIRQIRVGNTPETRGTAFVVYEDIFDA KNACDHLSGFNVCNRYLVVLYYQSNKAFKKLDQTKKAEELDQMKAKYGLSTPEMKMSIGV PIKVLHEAEGHIVTCETNTGEVYRGKLVEAEDNMNCQMSNITVTYRDGRVAQLENVYIRG SKIRFLILPDMLKNAPMFKKVGAGRGKSAILRAAARGRGRGGPGGGRGGMQNEAGEYVDM YIPRKCSASNRIITARDHASMQINFAEVDESTGRMTGHYKTYAICGDIRRMGESDDC--- ----------MARGPRKHLKRLHAPKHWMLDKLGGVFAPRPSTGPHKLRECLPMAVFLRN RLKYALTYDEVKKIVNQRLIKVDGKVRTDKTYPAGFMDVIAIEKTGENFRLIYDVKGRFA VHRISNEEAKYKLCKVKLVRVGPKGVPFLVTHDGRTIRYPDPAIKVHDTILLMGTKDDEY DYLFKVVLIGDSGVGKSNLLSRFTRNEFNL-GKSTIGVEFATRSIQVDGKTIKAQIWDTA GQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADNNIVIMLVGNKSDL RHLRAVPTDEAKAFAEKNNLSFIETSALDSTNVETAFQNILTEIYKIVSQKQIRDSPDDN NVQTITVAPTDNSAGGKKPCCSMSSRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVR GKDIVVLGVEKKAVAKLQEDRTVRKIALLDEHVAMAFAGLTADARILINRARIECQSHKL TVEDPVTLEYITRYLAQLKQRYTQSNGRRPFGLSTLLMGFDGTPHLYQTDPSGTYHEWKA NSIGRSAKTVREFLEKHYTDEVASEKETIKLALKALLEVVQSGSKNMEIAIMRLNEPLK- ------------------------------------------------------------ -------------------------------LKPQEEFIKNQERLKPQEEKQEEERSKVD DLRGTPMSVGSLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDVLEPGCSVLLNHKVHAVV GVLSDDTDPMVTVMKLEKAPQETYADIGGLETQIQEIKESVELPLTHPEYYEEMGIKPPK GVILYGAPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEENAPS IVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPA LIRPGRIDRKIEFPLPDEKTKRRIFNIHTSRMTLSTDVNLEDYIMAKDDLSGADIKAICT EAGLLALRERRMKVTNEDFKKAKENVLYRKNEGTPEGLYLKRKPYSPFQNKSNAEFAMAR VDDLINWARKSSLWPLTFGLACCAVEMMHFAAPRYDMDRFGVVFRASPRQADCIIVAGTV TNKMAPALRKVYDQMPEPRWVISMGSCANGGGYYHYSYSVLRGCDRVIPVDVYVPGCPPT AEALLYAILQLQKKIKRMKTVQMWYRK-DFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYA NNSNYKNDTMIRKEAFVHKSVMEELKRVIEDSEVMQEDDNLWPPPDRVGRQELEIVIGDE HISFTTSKIGSLVDVNQSKDPEGLRTFYYLVQDLKCLVFSLIGLHFKIKPIXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMTEYKLVVVGAGGVGKSA LTIQLIQNHFVEEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGF LCVFAVNNTKSFEDINQYREQIKRVKDADEVPMVLVGNKVDLPARTVETKEGRMLADSYG IPYIETSAKTRQGVDDAFYTLVREIRKFMGDRYNIHSQLEHLQSKYIGTGHADTNKWEWL TNQHRDSYSSYLGHHDMLNFFSVVENEAKARVKFNLMERMLQPCGPPPERPEDXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMKLNISYPATGCQKLIDIDDDKKLRHFYEKRISAEVDANHLGAEWQGYVFRIAGGND KQGFPMKQGVLSNGRVRLLLSKGHSCFR-------------------------------- --------------------------------QDDVRKCVVRREISKTTKAPRIQRLITA TRLQRKKRLLSLQRKQCQNTRAAAKEYEVIIANHKNAEKEKRAHLVAKKKHVVKVKAKDL RSKKREDLEKQLLELKQELASLRVNKVTGGAASKLSKIHTVRKSIARVLTVIHQTQKENL RKFYLPKDLRKKRTRAMRKDLTPHEKRLKTKKQQHRERLYPMRKFAVKKPKKGPKVTDKV YFDIEIGGKAAGRVVIGLFGKTVPKTVKNFKTIAEGTHTYKGSKFHRVIKEFMIQGGDFT RGDGTGGKSIYFEDENFKLKHYGSGWLSMANAGKDTNGSQFFITVKKTEWLDGRHVVFGK VLEGMKVIRKVEASETDRDKPKEDVVIADCGSLEVEKPFAVAKEPSSE------------ ---------------EKFLHERIKVNGKLNNLKSRLSVMSDIPFSKRYLKYLTKKYLKKH NLRDWLRVVASAKDTYELRYFQINNEEDEDEDGD-------------------------- -------------ALTSGTIKAMLSGPGQFAENETNEINFREIPSHVLQKVCMYFTYKVR YTNSSTEIPEFPIA----------------TKTYTLEEVKKHKNAQSCWLVIHDKVYDVT KFLEEHPGGEEVLLEQAGYYATEAFEDVGHSTDAREMMEQYLIGVIAEDEKGGMLSWLVP LGIAIAAAVLYKYL------------------------------------TCMVMDETLY RVAEKMKNFAVIYLVDVTEVPDFNKMYELYDPCTTMFFYRNKHIMIDLGTGNNNKINWAM EDEQEFIDIIETIFRGARKGRGLVVSPKDYSTKYRYKKLQKQLEFLEVQEEYIKDEQKNL KKEYLHAQEEVKRIQSVPLVIGQFLEAVDQNNGIVGSTTGSNYYVRILSTIDRELLKPSS SVALHKHSNALVDVLPPEADSSITMLGADEKPDVLYSDMGGYDIQKQEVREAVELPLTHF DLYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVR DVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVI MATNRHDTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITGKMNLSEEVDLEDYVARPD KISGADINAICQEAGMQAVRENRYVVLSKDFEKGYKNNVKKDETEHEFYKAHAPLTIPSI TERVLLVLKLYDKIDPEKLTIDSHFMNDLGLDSLDHVEVVMAMEDEFGFEIPDADSERLL KPADVVQYIADKMDVSRRVQAISEDLKNVEFETSEGVEVIPTFDSMGLREDLLRGIYAYG FEKPSAIQQRAIKPIQKGRDVIAQAQSGTGKTATFSISILQCLDTQVRETQALVLSPTRE LAVQIQKVILALGDYMNVQCHSCIGGTNIGEDIRKLDYGQHVVSGTPGRVFDMIRRRNLR TRSIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVLLISATLPHEILEMTSKFMTDPI RILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKM REANFTVSSMHGEMPQKEREAIMKEFRSGASRVLITTDVWARGIDVQQVSLVINYDLPNN RELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLIAQMRRP FDPVAHELDASFRLTKFADLKGGCKVPQEVLLKLLEGLQQG-DSEQAHFQYIAATPHIGI GMDACVTPLRHGGLSLVQTTDFFYPLVDDPYMMGKIACSNVLSDLYAMGVTECDNMLMLL ASSNKMSDKERDVVVPLMIRGFKDCAEEAGTSVNGGQTVINPWMTVGGVATTVCQPNEFI MPDSAVVGDVLVMTKPLGTQVAVNAYQWLDQPDRWNRIKLVVSEDDVRKAYQRAMFSMSR LNRTAARLMHKYNAHGATDVTGFGLLGHASNLARVQKNEVGFVIHNLPIIAKMAAVSKAC GNMFGLLQGQSAETSGGLLIALPREQAAAFCKDIEKQEGYQAWIIGIVEKGNRTARIIDK PRVIEVPAKEKE------------------------------------------------ ----------------RESNGKYTFSAHMDGVYKYCFSNKMSTMTPKIVMFTMDIGEKQK AHHNKLEEMINELSTSLTGVKHEQEYMQLRERIHRAINDNTNSRVVLWSFFEALVLVAMT LGQIYYLKGFFE-----MAATLKPYLTAVRHTLTAAVCLENFNSQVVERHNKPEVEVRSS KELLLTPVVISRNEKEKVLIEGSINSLRISIAVKQADEIEKILCHKFMRFMMMRAENFVV LRRKPIEGYDISFLITNFHTEQMYKHKLVDFIIHFMEEIDKEISEMKLAVNSRARISAEE FLKQFSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLV TMQIWDTAGQERFQSLGVAFYRGADC--------------------------------EN FPFVVIGNKIDLENRAVSTKRAQSWCQNKGGIPYFETSAKEAINVEQAFQTVAKNALAQE TEVELYNEFPDQIKLNDNSGKEGCACTAPFDTRFPNQNQTRNCWQNYVDTYRCKKIDDYE PCEYFWRTAKSLCPQEWIEKWDEQREANAFAGKIMPDHLGSDQRKTKDVDEEEKPIQSLD EGDIALLKTYGAGMYHRAIKSTEDDIQGVLKRVNELSGIKESDTGLAPPALWDLAADKQT LQSEQPLQVARCTKIINADSDDPKYIINVKQFAKFVVDLGDQVAPTDIEEGMRVGVDRNK YQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIDKLREVVETPLLHPERFVNLGI EPPKGVLLYGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARA KKACIIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDT LDPALMRPGRLDRKVEFSLPDLQGRANIFKIHARSMSVEKDIRYELLARLCPNSTGAEIR SCCTEAGMFAIRQRRKMATEKDFLEAINKVIKAYAKFSATPRYMTYNMGQEKTHINIVVI GHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITI DIALWKFETARYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQT REHALLAYTLGVKQMIIGVNKMDSTEPPYSEARFKEIQKEVSTYIKKIGYNPDAVPFVPI SGWHGDNMLNMTWFKHWEVYTGTTLLEALDNIDPPKRPTDKPLRLPLQDVYKIGGIGTVP VGRVETGSIKPGMVVTFAPANLTTEVKSVEMHHQTLEEALPGDNVGFNVKNVSVKDIRRG NVAGDSKNDPPKECGSFKAQVIILNHPGQIQAGYAPVVDCHTAHIACKFKELLEKIDRRS GKKLDDNPPFVKSGDAAIVEMVPQKPMCVESFVDYPPLGRFAVRDMRQTVAVGVIKSVDK RD-ATSKMTKAAQKA--------------------------------------------- -----------------------------GKLIVWDGYSTNKVHAIPLRSSWVMTCAYAP SGNYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDNQIVTSSGDMTCA LWDIETGQQTTSFTGHTGDVMS-------------------------------------- --------------------ATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLG GYDDFNCNVWDTLKQDRAGVLAGHDNRVSCLGVTEDGMAVCTGSWDSFLKIWNMSYAYLF KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES FRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHASSNMVIMLIGNKSDLEARR DVKKEEGEAFAREHGLIFMETSAKTAANVEEAFINTAKEIYQKIQDGVFDINNEANGIKI GPQHSPTNASGGSGGAQGGG--RGRTELGDVTVHNIKQLKRLNQVVFPVSYNDKFYKDVL EVGELAKLAYFNDIVVGAVCCREDKSDNQRRLYIMTLGCLAPYRRLGIGTVMLQHVLTIC EKDANYDNVYLHVQVNNESAIKFYEKFGFEIVEKKQNYYKRIEPADAFVLQKTFR-XXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX------------------------------------------------RLKHIPRPK LQVCVLGDEQHCDEAKANEVPYKDVDSLKKLNKNKKLVKKLAKKYDAFLASDSIIKQIPR ILGPGLNKAGKFPTMLTHGESMSGKVDEVKATIKFQMKKVLCLAVAVGHVNMKHEELTAN VALAMNFLVSLLKKNWQNVRALYIKSTMGPSRRIYMADSDKLVIDSIIARLLEVRGSRPG KNVQLTETEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLNAGRPVTPPRGGAKNK GKMMFKNTFQSGFLSILYSIGSKPLSIWDKKVRNGHIKRITDADIQSLVLEIVGTNVSTT YITCPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNY--------- ------------------------------------------------------------ -------------MTE-NIQNFQDPFAEDHDVHIRIQQRNGRKTLTTVQGIPPEYDFKKI VKACKKEFACNGTVVEHPEYGEV------------------------------------- ---------------------LLDKNKEGLLGIFWKFARIGERKSPYVAVCCVAMAVSLL FWS--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----VDSLVPIGRGQRELIIGDRQTGKTAVAIDTIINQKRFNEGQDEKAKLYCIYVAIGQ KRSTVAQIVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCAMGEFFRDNGKHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDDFGGGSLTALPVIE TQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQMKAMKQVAG SMKLELAQYREVAAFAQFGSDLDAATQQLLSRGVRLTELLKQGQYVPMAVEEQVTVIYSG VRGHLDKLDPAIITKFEEEFLQHVKSTQQALLTKIRE----------------------- -----------LECPNLKLKRPGWLRWPSAMFIFAMIIFSYFLVTGGIIYDVIVEPPSIG STTDEKGNSKPVAFMPYRVNGQYIMEGLASSFLFSMGGLGFVILDQTNKPMTPRLNRIL- ------------------------MGKVRKSRKPPPDGWELIEPTIDELDQKMKEAETDP HEGKRKVEGLWPIFKIHHQKSRYLFDLYYKRKAITKELYEYCIKEGIADKNLIAKWKKQG YENLCCLRCIQARDTNFGTNCICRVPKSKLEDARIVECVHCGCRGCSGEYAQVTKMLGNG RLEALCFDGVKRLCHIRGKLRKKVWINTSDIILIGLREYQDTKADVILKYTADEARSLKA YGEIPESAKINEDGDDIITFEDIDDIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSIMAK PKSEMTPEELAEREQEEFNTGPLSVLTGSVKNNTQVLINCRNNKKLLGRVKAFDRHCNMV LENVKEMWTEVPKTGKGKKKSKPVNKDRYISKMFLRGDSVILVLKNPMXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXA GDVDKGKKLFVQRCAQCHTVEAGGKHKTGPNLNGLMGRKTGQAPGFQYTDANKSKGITWS KETLFVYLENPKKYIPGTKMIFAGLKKPKERGDLIAYLEASTKIFVERTLAIIKPDSLSE EIEDIILRSGFTILQKRRVHLTPEQASDFYAEHYGKLFFPSLVAYMSSGPVNAMVLAREK SIAYWRELVGPTNTLKARETHPDCLRAIYGTDDQRNGLHGSDSYTGAEREIRFFFPDSVV EPVAVGQAAKDYLAKSVNPTLLKGLTELCKQKPLDPVVWLADWLLENNPNKPKVKMFEAR LAQGALLKKVLEAIKDLLNEATWDCNGTGMSLQSMDSSHVSLVSLSLRCDGFDTYRCDRN LSMGINLASMSKIMKCASNEDAITIKAGDNADTVTFMFESPNGEKVSDYEMKLMDLDTEH LGIPETDYSCVVKLPAAEFQRICRDLSQIGESVVICCTKEGVKFSANGDLGTGNIKLAQS ANVDKEEEAVIIEMNEAVTLTFALRYLNYFTKASPLASQVSLSMSPDVPLVVEYKIGDMG YIRYYLAPKIEDEAE-KSFAAYHTTRKVIKGRVVAVIGAVVDVQFDEDLPPILNALEVAN RSPRLILEVAQHLGENTVRTIAMDGTEGLVRGAECVDTGTPISIPVGPETLGRIINVIGE PIDERGPVNAKHYAAIHAEAPEFTEMSVEQEILETGIKVVDLLAPYAKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIEGGVISLKDDTSKVSLVYG QMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIA ELGFYPAVDPLDSSSRILDANIVGMEHYTVARNVQKVLQDYKSLQDIIAILGMDELSEDD KLTVARARKMQRFLSQPFQVAEVFTGSAGKLVNLQETIKGFKMILSGELDHLPEVAFYMV GPIEEVIQKADKLAEERMLIPKKNRVAIYESLFKEGVMVAKKDFYAPKHPEMDIPNLQVI KALTSLKSRGYVKEQFAWRHYYWYLTNEGIQYLRDFLHLPPEIVPATLKRQPQAQDRQEY RKGGGGDKKADVGAGAS------------------------------------------- ---------------GDASKFAEHVFRTFDTNGDGTIDFREFICALSVTSRGKLEQKLKW AFSMYDLDGNGYISRQEMLEIVTAIYKMVGTVMKMPEDESTPEKRTDKIFRQMDKNLDGK LSLEEFIEGARSDPSIVRLLQCDPMSSSEEVSWINWFCGLRGNEYFCEVDEDYIQDKFNL TGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQSAEMLYGLIHARYIMTNRGIAQ MIEKWQQGDFGHCP---------------------------------------------- ------------------------------------------------------------ MTNPKGYRRGTRYMFSRQFRKRGVIPLSTYMRVFKRGDMVDIKGNGAVQKGMP------- ---------------------GRIVAKRINVRVEHIKHSNCRLEFLKRVQENAEKKKVAK EKAVIKRQPAAPRPGHFVKSKHNKPQILKPIPYEFVAASLQHYRQMNPGEPSTAFGDMTT NAANRVFFTELFKGLGVVMSQLFKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAICPAQAITIEAEVRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEY STETHEELLYNKEKLLENGDKWEAEIASNLQADYLYR------------------DKEQQ EAIEQIDEVQNEIDRLNEQASEEILKVEQKYNKLRQPYFQNRSDLIAKIPNFWVTAFVNH PQVSALLNEEDEEALQFLTKVEVQEFEDIKSGYKINFHFDTNPYFENLSISKEFHLNSSK STPITWKNGKDLTKKSRKRNHEEQESFFAWFTDHGDAGADELGEVIKDDIWPNPLQYYLA SEVDEEGP--EDVDDELXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXX--QGKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQT VCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFSRAKSWVKELQRQ ASPNIVIALAGNKADLRMVEYEEAQAYAEENSLLFMETSAKTAMNVNDIFLAIAKKLPKN EQGVSLNQENMAEYLASIFGTEKDKVNCSFYFKIGACRHGERCSRLHNKPTFSQTVLLQN TYINPQNTAQVHVSDVEMQQHYDEFFEEVFVELETKYGEIEEMNVCDNLGDHLVGNVYVK FRYEEDAEKAVNELNNRWFNGRPVHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKP ISRELRRE-------------------------------------MFLTRSEYDRGVNTF SPEGRLFQVEYAIEAIKLGSTAIGIQTAEGVVLAVEKRVTSPLIETSSIEKIMEVDNHIG CATSGLIADSRTLIDRARVEAASHWFTYNEKMSLESVTQAVSNLALQFGDDDADAGAMSR PFGVALLFAGIDAKGPQIYHMDPSGTFIQYDAKAIGSGSEGAQQALQEVYHKSMTLKEAS KQALIILKQVMEEKLNSTNVEMATVTPDKMFRMLSKEELEDII----------------- ------------------------------------------------------------ --------------------TETRVNAQAQAYEYMAAYTESAKQVGRLENVIGWYHSHPG YGCWLSGIDVSTQMLNQQFQEPFVAIVVDPVRTISAGKVNLGAFRTYPKGYKPPDEGPSE YQSIPLNKIEDFGVHCKQYYSLDVSYFKSSLDRRLLESLWNKYWVNTLSS---------- ------------------------------------------------------------ ------------------------------------------------------------ -----MSAPKVRFMTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPD DPLDNNVAEQWKCNESQAIETAKQWTRLYAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPSYADLG KSARDLFSKGFNYGFYKGELKTKTECGAQFTTSGSHNHDSGKVNGSLELKYKWKDYGLEF VEKWNTDNTLGTEMTIEDQLAKGLKLSFDTTFAPQTGKKSGKIKTAYKHEYVNANCDVDF DFAGPTVHGAAVVGYNGWLAGYQMSFDKSKLTRNNFAVGYKAGDFQLHTSVNDGSEFSGS VYQKVNDELETGCSLSWTAGSNATKFGVAAKYCPNSEITYRVKVNNASQIGLSYQQKLRD GITLTMSSLLEGKSFNQGGHKMGLGFDFE--SVREKALTDYRKKLLEHKELEARLKEMRE QLKELTKQYEKSENDLKALQSVGQIVGEVLKQLTEDKFIVKATNGPRYVVGCRRQIDKTM LKSGTRVALDMTTLTIMRYLPREVDPLVYNMSIEDPGTINYSQIGGLSEQIRELREVIEL PLKNPELFQRVGITPPKGVLLFGPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIGES ARLIREMFGYARDHQPCIIFMDEIDAIRRFSEGTSADREIQRTLMELLNQMDGFDALGQV KMIMATNRPDTLDPALLRPGRLDRKIEIPLPNEQARMEIMKIHAAPIAKHGEIDWEAVVK LSDDFNGADLRNVCTEAGMFAIRAERDYVIEEDFMKAVRKVSDNKKLESKLDYKPVMPES LGSVIRKFYDDYITNTPKKLKLIDAYLAYILLTGVVQFGYCSLVGTFPFNSFLSGFISCV GCFVLAACLRIQVNPQNKSEFHGISPERAFADFIFAHIVLHLVVMNFIGSLTSPSQLLPL ELVDKCIGSRIHIIMKNDKEMVGTLAGFDNFVNMVLEDVTEFESTPEGRRVTKLDQILLN GNNITMLVPGGEGP-VIDHYENPRNVGALDKXEKNVGTGLVGAPACGDVMKLQIKVDDDG KIIDAKFKTFGCGSAIASSSLATEWIKGKTLNEAGDIKNQDIAKELCLPPVKLHCSMLAE DAIQAALKDYRVKNQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXMGKFMKTGKVVLVLGGRYAGRKAVIVKNYDEGTGEKGYGHALVA GIDRYPLKVNKRMGKKRLKQRSKIKAFVKVLNFTHLMPTRYSVVNLNKNVVNKEAFRDPA QRKKAKMEAKLKFEERYKTGKNRWFFTKLRFXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSA TPAPVK---RAKEKALKAKKAVLRGVHNKRKKKVRNSVQFKRPKTLAKPREPKYPRKSVP RRNTLDQFKIIKFPLTTESAMKKIEDNNTLVFVVEKLANKPQIKNAVKKLYNIDVSKVNT LIRPDGEKKAYVRLAPDYDALDTASKIGVIMPTKQRMRIQNEKHSKNVANRGNVPKTLKS AEEKYPVGPWLLALFVFVVCGSAIFXYTHDVR-VKIKGWTAVATWRWIANDDNCGICRMP FDGCCPDCKLPGDDCPLVWGQCSHCFHIHC-XKWLNSQQIHQPCPMCRQEWKFKEMIRFI LIQNRAGKTRLAKWYMHFDDEEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIVYRRYAGL YFCICVDITDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYSVVDEMFLAGEIRE TSQTKVLKQLLMLSSLE-PTIFSKIIDKSIPTDVIFEDDKCLAFRDISPQAPLHFLVIPK KVIAKLSADSKLLGHLLLVAKKVAKEEKGFRVVINNGEHGAQSVNHLHLHVLGGRQMNWP PXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX X-------------------------GIYKVELYDKLRNEYVKTMAGLGMHVEIRDPEDK TVMSRTYAAEGRFTFSSQTAGEHIICLHSNSTAWFGGGQMRIHLDIQVGEHANDYQQIAA KDKLTELQLRVRQLLDQVEQITKEQNYQRYREERFRQTSESTNQRVLWWSIAQTLILLTT GFWQMRHLKSFFEAKKLVMFYHVSLEHEILLHPRYFGPNLLNVVKQKLFTEVEGTCTGKY GFVIAVTTIDNIGAGIIQPSRGFVVYPVKYKAIVFRPFKGEVLDAVVTQVNKVGLFTEIG PMSCFVSRHSIPSDMEFDPNSNPPCYKTKDEDMVIQQDDEIRVKVVGTRVDATDIFAIGT LMDDYLGLVSRLYVKAVFTGYKRGLRNQHENTALLKLEGVDTKKETDFYLGKKCCYVYKA KKKTACPGHDLPSRLRVIWGKVTRPHGNSGAVRAKFRRNLPPKAMGKRIRIMMYMAKKTY DLLFKLLLIGDSGVGKTCLLFRFSDDAFNTTFISTIGIDFKIKTVELGGKKIKLQIWDTA GQERFHTITTSYYRGAMGIMLVYDITNAKTFDNITKWIRNIDEHANEDVEKMILGNKCDM EDKRQVPKVKG------------------------------------------------- ------------------------------------------------------------ --------PEGAVPAYLLDREGQTRAKVLSNMVKQKRKEKAGKWEVPLPKVR-XSEAEAF KVVKTGKSRRKAWKRMVTKVTYVGDTFTRKPPKYERFIRPMALRFKKAHVTHPELKATFC IPIIGVKKNPSSPTYTQLGVITKGTIIEVNISELGLVTTGGKVVWGKFAQVTNNPENDGC INAILLVMASRPLVTVYNEKGETTPTHVSLPSVFRAPIRPDIVSFVHSEMRKNTRQPYAV SVRAGHQTSAESWGTGRAVARIP-----GTHRSGQGAFGNMCRSGRMFAPTKTWRRWHRR ININQRRYAI------------------------------TDKVQEYKKTKEAVLLLKKL KAWTDIEKVKATRRFRAGKGKMRNR----RXXXLVVYGKDNGITKSFRNIPGITLLNVNR LNLLKVAPGGHVG-------------------------------------------RIIN SDEVQTALNPMKEPPKRKSQHKNPLKNKYVLARLNPIAM--------------------- ------------------------------------------------------------ -----------------------------------------------KENRRYFLDLKEN QRGRFLRVSPRSQQRSQIAIPAQGMIEFRDALTDLLDEFGTDDHEGLGELPEPKSMRVEN KMFYFDVGQNRRGVFMRISETNFRTAITIPEKSWARFRDVLSDFVDKXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXMNIRNAQPQDLMNMQHCNLLCLPENYQMKYYFYHG LSWPQLSYVAEDEKGKIVGYVLAKMEEDPEDSVPHGHITSLAVKRSHRRLGLAQKLMDQA SRAMVECFSAKYVSLHVRKSNRA------------------------------------- ----MSHTILLVQPGKKPEGRTYSDYESVNECLEGVCKIYEEYLKRMNPNSPSITYDISQ LFDFVDQLADLSCLVFQKSTSTYVPHNKDWIKEKIYILLRKQAGKMAEQTEEKKEPETKR VVHTYPLIRHSDMNEEMRVEAMELCVTACEKFSSNNETAAKMIKETMDKKFGASWHVVVG EGYGYEITHEVKNLLYMFFGGTM--------MSHRKFSAPRHGSLGFLPKKRSRRHRGKA KSFPKDDPTKPVHLTAFIGYKAGMTHVVREVDRPGSKLHKKEAVESVTIIETPPMVVVGM VGYIETPQGLRTFKTIWAEHLSEECRRRFYKNWYRCKKKAFTKNAKKWQDENGKKEIEKD IKKMQKYCKVIRVIVHTQIKLLKKRQKKAHIMEIQLNGGTMKDKIEWAKSHLEKQVTVDT VFSQDEMMDVIGITKGKGYRGVTSRWHTKKLPRKTHKGLRKVACIGAWHPARVAFSVARA GQKGYNHRTEVNKKIYRIGKGIHTKDGKVVKNNASTEYDLTEKTITPMGGFPHYGEVNQD YLMIKGCCMGPKKRVITLRKSLLVHTKRRAAEKINIKFIDTSSKFGHGRFQTREEKQNFM GPLKKD------------------------------------------------------ ------------------------------------------------------------ ------------------------YPQGLAMAKEIGAVKYLECSALTQKGLKTVFDEAIR AVLCPKPKPKKKKTCRIL-------KKKKKKAGFDLDAALDDINLDDGLAKKKKKKKKPF DMSEIEATLPKDEGSLPFKKKKGDTDRDYTYDELLKRVFDIMREKNPDMVAGEKRKFVMK PPQVMRVGTKKSSFSNFHEICKLLHRQPKHLLAFLLAELGTSGSVDGNNQLIIKGRFQQK QIESVLRRYIKEYVTCHTCRSPDTILQKDTRLYFLQCETCGSRCSVATIKSGFQAVTGKR AAIRAKET---------------------------------------------------- -------------SDEQNHLLIASVQLPNDNAQFDASHYDSEKGEFGGFGSVSGKIEIEI KINHEGEVNRARYMPQNPCVIATKTPSSDVLVFDYTKHPSKPDPSGECHPELRLKGHQKE GYGLSWNPNLNGNLLSASDDHTICLWDINTPPRDGNVIDAHTIFNGHTSVVEDVSWHLLH DSLFGSVADDQKLMIWDTRSTNTSKPSHVVDAHTAEVNCLSFNPYSEFILATGSADKTVA LWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQSAEDA EDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEEPDTPAS ELE--APSRARVYADVNTHRPRDYWDYESHVVEWGQQDDYQLVRKLGRGKYSEVFEAINI TNNEKCVVKILKPVKKVKIRREIKILKNLRGGPNIIALLDIVKDPVSRTPALIFEHVNNT DFKQLYQTLTDYDIRYYMFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLA E----------------------------------------------------------- ------------------------------------------------------------ -------------------------------QVPETLLKKRKQKERKAIGKKREIFKRAE KYVKEYRIRERDEIRMARVARNHDNFYVPAEPKLAFIIRTRGINGIHPRPRKVMQLFRVR QINNGTFVKLNKATLNMLRLADPYITWGYPNLKSVRELIYKRGFGKIDGRRIPLSNNAVI EQKLGKFGIICMEDLIHEIFTVGPNFKAANNFLWHFKLNTPNGGWTKKNNHFVDGGDFGN REDKINTLLRRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSKAHPPELKKYM DKKLTLRLNGGRQVTGTLRGFDPFMNLVIDETIESRKTGEQVSIGMVVIRGNSVVLLESM DRI------------------------------DSFDNTYQATIGIEYLSKTMYLEDRTI RLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFQQTSKWIDDVRTERGSDVIIM LVGNKTDLSDKRQVSTEE------------------------------------------ -----------------MGAKYEMAIGLKKGHRVTKKKPRPSRRKGVLTKHNKFIRDIIR EVAGLAPYERRTVELLRISKDKRALKFCKKRLGTHIRGKRKREELMQTIQQMRKA----- -------------------GDLWVQRLKEEYQALIKYVQNNKEADNDWFRLESNKEGTRW FGKCWYIHELLKYEFDVEFDIPVLYPTTAPEIALPELDGKTAKMYRGGKICMTDHFKPLW ARNVPKFGIAHAMSLGLGPWLAVEIPDLIAKDIIKHKE---------------------- --------------------------------------------------NQADPIRVGD IVVFKVEGREIPIVHRVLKVHERNNGTVKFLTKGDNNQVDDRGLYAPGQLWLEKKDVVGR AKGFVPYVGIVTILMNDYPKFKYAVLALLGIFVLIHREMSTMNPEYDYLFKLLLIGDSGV GKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYR GAHGIIVVYDVTDQESFNNVKQWLQEIDRYASDNVNKLLVGNKCDLTTKKVVDYTTAKEY ADQLGIPFLETSAKNATNVEQAFMTMAAEIKNRMGPVASAPNVKINPSQPVKQSGGGCC- ------------------------------------------------------------ ------------------------------------------------------------ ---DLVGVNKDSYLILEKLPQEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELIEAVVLP MTHRERFETLGIQPPKGVLLYGAPGTGKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGA KLVRDAFALAKEKAPAIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNSD IKVIAATNRVDILDPALLRSGRLDRKIEFPTPNEEARARIMQIHSRKMNVSSDVNYEELA RCTDDFNGAQCKAVCVEAGMIALRRGASELSHEDYMDAIMEVQAKKKANLQYYAXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXAGPGFVGIKFCQECNNMLYPKEDKENKILLYACRNCDYQEE SDNPCIYVNKIAHEVDELTQIIADVVADPTLPRTEDHPCPKCGHREAVFFQSQTRKAEEK MNLYYVCTLSSCAHRWTE------------------------------------------ ------------------------------------------------------------ ---------------------NMILDDGGDLTNLVHSKYPQYLEGIKGLSEETTTGVHNL YKMMAAGTLKVPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGKVACVAGYGDV GKGCAQALRAFGARVIITEIDPINALQAAMEGYEVSTMEDACSRARIFVTTTGCKDIIKP DHMVEMLEDAIVCNIGHFDCEINVKWLNDNCTKKDTIKPQVDRYTMKSGRHIILLAEGRL VNLGCAMGHPSFVMSNSFTNQVLAQLELWTKADQYKLGVHFLPKKLDEEVAFAHLEQLGV KLTKLSADQAEYLGIPKDGPFKPEHYRYAEEPDQASANTVEEPLDLIRLSLDERIYVKMR NDRELRGKLHAYDQHLNMLLGDVEETVTTVEIDEETYEEIYKSTKRNIPMLFVRGDGVIL VSPPMRTMSSSNVENLNPHVLRQVARELGELVSDPPEGIKVHMNDEDITDIQATIEGPAG TPYAGGVFKMKLILGRNFPSEPPKGFFLTRIFHPNVASSGEICVNTLKRDWKAELGIKHI LLTVKCLLIVPNPESALNEEAGKLLLEQYDDYCTRARLYTDIHAKPMFKSLIDTAKNSPF ASPFGLKVNENRVISAAGEEYSCEFGDNKYYALCGFGGILSCGITHTAVVPLDLVKCRIQ VDPAKYGNIINGFRVSVRESGIRELGKGWAPTLIGYSMQGLCKFGFYEVFKIFYGNLIGE ENTFLWRTSLYLAASASAEFFADIALCPMEACKVRIQTQPGWAKNLREGFPKLMAEEGAW GFYKGIVPLWGRQIPYTMMKFACFERTVEALYKFVVPKPRAECSKSEQLIVTFVAGYIAG VFCAIVSHPADTIVSKLNQDKTASFMGVAKNLGWLGMWKGLFPRIIMIGTLTALQWFIYD SVKVYFRLPRPPPPEMPESLRRKLEHWMNERYVAAALIPIIPIALACILDTALSAMVLHS HWRLSGVAHDYIHLSICAFGSLCYFNYYDIGFAKAVQMIYTQLNEPPEEDASELIFAKEF ENAETLLISEVQRKQQNENAEEEQEMSEVFMKTLNYTQRFSKFKNRETIAAVRSLLMQKK LHKFELAALANLCPESADEAKALVPSLEGRFEDEDLQQILDDIQTKRSFQY--QLHLARQ DLENLDAAKLTPLTPEVISRQATINIGTIGHVAHGKSTLVKAISGVQTVRFKNELERNIT IKLGYANAKIYKCNDPSVGRPQCYTSRGSAHPDDFPCDVGGSGKFKLVRHVSFVDCPGHD ILMATMLNGAAVMDAALLLVAGNESCPQPQTSEHLAAIEIMKLKHIIILQNKIDLVKDSQ ARDQYDQILKFVQGTIAEGVPVIPISAQLKYNIDAVCEYIVKKIPVPLRDFTSEPRLIVI RSFDVNKPGCEVDDLKGGVAGGSILRGVLKVGQEIEVRPGIVSKDQEGKLICRPIRSRII SLFAEQNDLQFAVPGGLIGVGTKIDPTLCRADRMVGQVLGAIGALPDIYIELEISYFLLR RLLGVRTEGDKKGAKVQKLAKNEVLMVNIGSLSSGGRVLAVKADLAKVGLTSPVCTEIGE KIALSRRVEKHWRLIGWGQIRRGVTIKP--ELLLDSNIRLWVFLPIVVITFLIGILRHYV TILLSSEKKVELQQIANSQALIRSRMLRENGRFLPKQAFLMRKEFFNHEESGYFMKNPMT DPSMMTDMLKGNITNVLPMIVIGGWINWAFSGFLTTKVPFPLTLRFKPMLQRGVELVSLD ASWVSSASWYFLNVFGLRSMYNLILGQDNAADQTKVMQDHLSGAAVSMPQDPSKAFKAEW EALEICEHHWALEGVEEEL-MFLWDWFAGILNFLGLYKKSGKLVFLGLDNAGKTTLLHML KDDRMAQHVPTLHPTSEELTMGGMRFTTFDLGGHAQARRVWKDYFPAVDGIVFLIDCFDR ERMTEAKAELDSLLTDEQIANAPVLILGNKIDIPGAASEDEVRYAFGLHGQTTGKGVVSR SELRPMELFMCTVLKRQGYGEGFRWLAQYIN----------------------------- ------------------------------------------------------------ -QMTATEQWIFLCAAHKTPKECPAIDYTRHTLDGAACLLNSNKYFPSRVSIKESSVAKLG SVCRRVYRIFSHAYFHHRQLFDEYENETYLCRRFTTFVTKYNLMSKDNLIVPILEDQ--- IKLQSSDGEIFEVDVEIAKQSVTIKTMLEDDEDEEEAVPLPNVNAAILKKVIQWCTYHKD DPPPPEDDENKEKRTDDISSWDMEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMI KGKTPEEIRKTFNIKNDFTPAEEEQVRKENEWCEEKXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------- --------------------------------------------------------LYLV ATTKKNSNVSLVFQFLHKIVQVFCEYFKELEEESIRDNFVIIYELMDELMDFGYPQTTDS RILQEFITQEGHKLEVAPRPPMAVTNAVSWRSEGIKYRKNEVFLDVIESVNLLVSASGNV LRSEIVGAVKMRVYLSGMPELRLGLNDKILFESTGRGKSKSVELEDVKFHQCVRLSRFEN DRTISFIPPDGEFELMSYRLNTHVKPLIWVESVIERHAHSRVEYMIKAKSQFKRRSTANN VEILIPVPPDADSPKFKTTVGSCKYTPDQNAVVWTIKSFPGGKENLMRAHFGLPSVLGED SEARPPIHVSFEIPYFTVSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRTQ------ ------------------------------------------GGTGEGFDVAKTGDARIG FVGFPSVGKSTLLTNLAGVYSEVAAYEFTTLTTVPGVIKYKGAKVQLLDLPGIIEGAKDG KGRGKQVITVARTCSLIFMVLDVLKPLQ-------------------------------- ------------------------------------------------------CVYVLN KIDQISVEELDIICKLNHCVPISAHHKWNYDELLEKMWEYLALVRIYTKPKGQLPDYEAP VVLKAGYQTVEDFCNKLHRSIMK------------------------------------M AKHHPDLIFCRKQPGVAIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGSYQGRCVIC GGPGVSDAYYCKECTIMEKDRDGCPKIVNLGSAKTDLFYERKKYGFKKRPNLPPVAGDKI SGKGQLRKIPVPPHRYTPLKENWMKIFTPVVEHLNLQIRFNLKSRNVEIKTCKQTTDVGA LQKAADFVRAFTFGFEIDDALALVRLDDLYLESFEINDVKPLKGDHLSRAIGRIAGRGGK TRFTIENTTKTRIVLADSKIHLLGSYQNIRTARTAICSLIMGSPPSKVYGTMRTVAARIN ERRIKVANPVVELDGDEMTRIIWENIKEKLVFPYLDLDCKYYDLGLPHRDSTDDQVTIDS ALAIQKYNVGIKCATITPDEERVEEFKLKKMWLSPNGSIRNILGGTVFREPIICKTIPRL VPGWTQSIVIGRHAHGDQYKATDFVVKKPSKFELVITPEDGSETRLQAFNFKE-GGVLMG MYNTDESIRGFAHACFQYALKKKWPLYMSTKNTILKAYDGRFKDIFEEIYEQTYKSDFDK QGIWYEHRLIDDMVAQALKSNGGFVWGCKNYDGDVQSDVVAQGYGSLGLMSSVLMCPDGK TIEAEAAHGTVTRHYREHQKGNPTSTNPVASIFAWTRGLEHRATLDGNPELARWCGVMEK ACVDTIDSGKMTKDLAGCIYGLKNVTPDQYLYTSDFLDAILQEFE--------------- ------------------------------------------------------------ HYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMKPYEI QEKLGLTRIRDRNWYVQPSCA-------------------FGDLKTETGVCALNEFLADK SYIDGYEPSQADNVIFTQLTNPAATFVHALRWFNHISSYGNEKDGFAGTKKAANAYGPEG AANGADDDDFDLFGSEAQKLKEERVAAYTAKKAAVLIAKSSIVLDVKPWDDETDMAEMEK LVRTIESDGLLWGASKLVPLAYGIRKLQISCVVEDDKVGTDFLEEEITKFEDVVQSVDIA AFNKIKVQEVREVTRIERIGAHSHIRGLGLDDALEARNVSQGMVGQTSARRAAGVVLEMI KDGKIAGRAVLIAGQPGTGKTAIAMAIAQAIGTDTPFTAMAGSEIFSLEMGKTESLTQAF RKSIGVRIKEETEIIEGEVVEIQIDRPATGTGAKVGKLTLKTTEMETIYDLGQKMIESLT KEKVQAGDIITIDKATGKITRLGRSFTRARDYDAMGSQTRFVQCPEGELQKRKEVVHTVS LHEIDVINSRTQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIVPGVLFIDEVHM LDIECFSFLNRALENDMAPVLIMATNRGITRIRGTNYASPHGIPIDLLDRLLIVSTTPYE EKEIKQILKIRCEEEDVEVSDDALTVLTRIGMETSLRYAIQLITTAHLVCRKRKGTEVSV DDIKRVYSLFLDESRSTQFLKEYQQEFMFSE----------------------------- -----------------------------------------------------RRFNSDT DAIIKIFEDPEVNLQTARDGRQLFQYLAENHSFKESDVDTLYQFAKFQYECGNYSGAAEY LYFVRVLLPPHDKNYLNALWGKLASEILMQNWEAALDDLNRLKEVIESALQSLQQRTWLI HWSLFVFFNHAKGRDLIIDMFLYQQQYLNAIQTMCPHILRYLTTAVITNKNVLKDLVKVI QQESYTYRDPITEFLECLYVNFDFDSAQQKLRECETVLVHDFFLVACLNDFIENARLFIF ETFCRIHQCLSINMLAEKLNMSPEDAERWIVNLIRNARLDAKIDSKLGHVVMGAQAVSPY QQVIEKTKGLSFRSQMLAMHIEKKLGSK--------------KSFPQAGQKVAVHYTGTF PDGRKFDSSRDRGQPLEFTLGAGEVIKGWDEGVKQLSLGQRAKLTCTPDFAYGASGIGGV IPPNATLIFDVQLVSFKMPKYYCDYCDTYLTHDSPSVRKTHCNGRKHKENVRIYYQKWLE EQVQKLVDDTTAAFKAGKIQNNPFQAGGAMIPPPPSL----------------------- -----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXX---LLASVLADPTIYFKEEFWESRWVESTKKGAEQ GKFKWTAGKFYGDAELDKGIQTSEDARFYGISSKLDEPFSNEGKTLVIQFSVKHEQNIDC GGGYMKLYASDLEQTELHGESPYHIMFGPDICGPGTKKVHVIFTYKGKNLLTKKDIRCKD DVFSHLYTLIVRPDQTYEVKIDNKKVESGNLEDDWEFLPPQKIKDPEAKKPDDWDEREQI DDPDDTKPEDWEKPEHIPDPDAKKPDDWDDEMDGEWEPPMIDNPEYKGEWKPKQIPNPAY KGKWVHPEIDNPEYSPDDNLYRYNDIGATGFDLWQVKAGTIFDNILITDDEKYAEEFGEE TWGKTKDAEKKMKDEQDEDDRKKREEEDKKKKEEDDKK------MDTPVAEPTLFVVKAI LILDNDGHRLLAKYYDETFPTAKEQKNLFNKTHRANAEIIMLEGLTCVYRSNVDLFFYVV GSSSENELILVSVLNCLYDAISQILRKNVEKRALLDSMDGVFLAVDEICDNGIILESDPS AIVQRVSFRSDDIPLGEQTVAQVLQSAKEQIKWSLLKMNIFRLVGDLSHLLAIILLLLKI WKTRSCAGVSGKSQIMFAMVFLSRYLDLLTNFISPYNTVMKIIFIGSSVATVYLIYFKFK ATYDSNHDSFRMEFLIVPVAGLAFLVNHDFTPLEILWTFSIYLESVAILPQLFMISKTGE AETITSHYLFALGSYRALYIINWIYRYYFEGFFDLIAVVAGCVQTVLYCDFFYLYITKVW KGKKLTLPAMKIEEVKSTTKTQRVATHSHVKGLGLDDNGYAIQCSAGLVGQELAREAAGV VVEMIRCKKMSGRAVLLAGPPGTGKTAIALAIAQELGSKVPFCPMVGSEVYSTEIKKTEV LMENFRRAIGLRIKEKKEVYEGEVTELTPVETENPMGGYGKTVSHVIIGLKTAKGTKQLK LDPSIYESLQKEKVETGDVIYIEANTGAVKRQGRSDTYATEYDLEAEEYVPLPKGDVHKK KEVVQDVTLNDLDVANARPQGGQDILSMMGQLMKPKKTEITDKLRKEINKVVNKYIDQGI AELVPGVLFIDEVHMLDIECFTYLHRALESTIAPIVIFATNRGKCTIRGTEDLIAPHGIP LDMLDRLMIIRTLPYSQEEMMQILKIRAQTESIQIEDESLQILSVVGTKTTLRYAVQLLT PSALLAKINGKDLITKDEIEEINELFYDAKASAKILAEQEDKYMK--------------- --------------RSGVKDFEVMEVGGPGPQRSVEGWILFITNVHEEATEDEIIDKFAD YGDIKNLHLNLDRRTGFIKGYALVEY---------------------------------- ---MSYQLYRNTTLGHTLQESLDELIQLGQITPQLALKVLLQFDKAINNALATRVKNRVS FKGHLNTYRFCDNVWTLVLEDVEFRKVQKVKIVACDGKSTFLFTSESVGEGHPDKLCDQI SDAVLDAHLKQDPYAKVACETASKTGMVMLLGEITSKANVDYQKVVRDAVKYIGYDDSDK GFDYKTCNVLVALEQQSPDIAQGVHVGRDEDDIGAGDQGLMFGYATDETEESMPLTVVLA HKLNAKLSELRRNGELPWGRPDTKTQVTVEYRLQKGACIPVRVHTIVISTQHSEDVTTEQ LREDLREKVVKSVIPAKYLDANTVLHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAH GGGAFSGKDFSKVDRSAAYACRWVAKSLVKAGLCRRVLVQVSYAIGVAKPLSVFLSSYGT GAKSDKELLDIVNKNFDLRPGRIVKDLDLRRPMYQQTAAYGHFGRKEFSWEVPKKLVY-- --------------------------------------------TCFEGGIFPARVTFPA DYPLNPPKMRFTCDIFHPNIYADGRVCISILHSPGDDPMGYESSAERWSPVQSVEKILLS VVSMLAEPNDESAANVDAAKTWREDRAKFEEIADRTVRKSLGLMRLEKCYYCSSTIYPGH GVQFVRNDCKIFRFCRSKCHKGFKQKRNPRKVRWTKAFRKSAGKELTLDPALEFEKRRHV PVKYDRNLWKNTIKAMKRIEEIKTKRQSLFIKNRLKKGKELREEANKKEVEQNIHLIRAP GAGMATYTVVMIRHGESGWNKENKFCGWFDADLSELGIEEAKSAGQMLKEKKFTFDIAFT SVLKRAIKTLYYVQDGLDLHWIPVVRHWRLNERMYGGLQGLNKSETAAKHGEEQVKIWRR SYDTPPPPVETSSEHYPANDPKYKYVDTQLLPKAECLKDTVARVLPFWYDVIVPEIKKNQ KVLIAAHGNSLRAMVKYLDNMSDADIMALNIPTGIPLVYELDKDLKPVKHYYLASEEQVK AALDKVAAQGKA------------------------------------------------ ------------------------------------------------------------ ----KNCVIGRRCVLKDCCAIADNTVLPPETVVPPFTMFSGSP-XXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXMGIDINHKNDRKVRRTEPKSQDIYLRLIVKLYRFLARRTDA KFNKIILRRLFMSKNNRAPLSVARLARHMSKKGRDGKLAVCVGTITDDIRFLKMPKLRIC ALRVTTRARARILKAGGEIITFDQ------------------------------------ ------------------------------------------------------------ -----------------------------------------------EKVKGARLGCPFV WDGATIRTVLHVLKEHFTVYVTESAGHEMYRSLTEMGIPTVVILDSAVGYIMEKVDLVLV GAEGVMESGGIINKGTFSLALAAKELKKPLYVAAESYKFARLYPLN-QDIPNEFKYEAER EHPKVDYTPPRFITLLFTDLGVLTPS-----------MIIPVRCFTCGKVIGNKWESYLG LLQAEYTEGDALDALGLKRYCCRRMLLSHVDLIEKLLNYAPLEK---------------- ------------------------------------------------------------ ------------LLEVMEEEELANLRSQQRSFEELRNAELVEQQRLEEQERRHREEKERR MKQQREILRKERETADKIAARAFAQSYLADLVPSVFGTLADNGYFYDPVERDVEQGFL-- ------------------------------------MKARGQLKEYKVVGRRLPTPTLKV PPLYQMRIFAPDRPSAKSRFWYFVSMLKKMKKGSGEIVGVEQIHEKKPQLIKNFGIWLRY DSRSGTHNMYKEYRDLTAAGAVTQCYRDMGARHRARACSIQIRAVEPVPASKCRRAYTKQ FHDSKIKFPLPHRVARRLHHPRFTTKRPHTTFSAHDEMKEFWAKNQNRPSSPWIIYKPHL PMLTSLTHRTT----------XXITTFLAPGDFPMFVEAVKDLELPKAVLFSIKSICAFP LVYHYVNGIRHLTWDTGRGFELSTQYKSGWAIFGSMAYWAGSISLSAYRDQHFKGSRIDQ ELKLLESTTLYVGNLSFYTTEEQIHELFSRCGDIKRIIMGLDKQRKTPCGFCFVEYYLRE SAENCLRYVNGTRLDDRIVRTDWDAGFKEGRQYGRGKTGGQVRDEYRTDFDDGRGGYGKI TQQKL------------------------------------------------------- -------------------------------------------NYVFCCNFNPQSNLIVS GSFDESVRTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG KWIVSGSEDNQVYIWNLQTKEIVQKLQGHTDVVLCCACHPTENIIASAALENDKTIKLWK SDVMIIFKDLFSGDELFSDTYPGCVLKVKGKDEALLGANPSSGVNIVLAERKGYQSYIKD YMKTVKTFQFFLGVCLMKWETPYMYFFKHGLIEEKVMAVEFNEGVVVGADSRTTTGSYIA NRVTDKLTKVTDQIYCCRSGSAADTQAIADIVNYHLNFHKVELGEEPLVKTAASVFQDLC YGYRDQLSAGIICAGWDRRKGGQVYSIPLGGMCVRQPCTIGGSGSSYLYGFMDATYKEGM TKEECMKFCLNALSLAITRDGSSGGIARLAVITKDGVERKTVLSDDLPKFVVIALVAVLL LVCCCVCICKKCCKRKKKKDGKKGLKGAVDLKSVQLLGSTMKE---XDLEELEVNMEDNE DAESTKSEVKLGKLQFSLDYDFQKGELNVGVIQAADLPGMDMSGTS-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------LRVIFRSVIDFDEMAAGLNKRRMI QSAVFKELMKLIDPGVKAWTPTKGKQNVIMFVGLQGSGKTTTCTKLAYYYQKKGWKTCLV CADTFRAGAFDQLKQNATKARIPFYGVDTSGRHKQEESLFEEMLEVSNVDPHNVVFVMDA SIGQACEAQARAFSDKVNVASVIITKLDGHAKGGGALSAVTKSPVIFIGTGEHIDDFEPF KVQPFVSKLLGMGDIEGLVDKVKDLGLDDEELMKKLRH---------------GQFTL-- ---------MSIMSYNGAAVVAMKGKNCVAIASDKRFGVQAQTVAIDFQKLFEMGPNLYM GLPGLATDVQTVAQRLKFRLNLYELRENRRIKPKTFMSMVSNLLYERRFGPYFIEPVIAG LDKKTNEPFVASLDLIGCPMVTEDFVVSGTCTEQLYGMCESLWEPDMDPDTLFECIS--- ----------------------------------MTSKDYYFDSYAHFGIHEEMLKDEVR TLTYRNAMYHNRHLFKDKVVLDVGSGTGILCMFAAKAGAKKVIGIECSEIVEHARNIVKA NKLDDVITLVKGKVEEVALPDGIEKVDIIMSEWMGYCLFYESMLKTVIFARDKWLAPDGS IFPDRATLYICAIEDRQYKDEKINWWDNVYGFDMSCIRKVAISEPLVDVVDPKQVVTNSC LVKEVDIYTVTEDDLAFQAPFHLQCRRNDYIQALVTYFNMEFTKCHKRTGFSTAPGERYT HWKQTDNEMTVNKGEEVYGTFAVKPNKNNHRDLDFTIEVDFQG--------------MVR EDKASWKSNYFLKLGELLQEYPKCFIVGADNVGSKQMQHIRIALRVLMGKNTMMRKAIRG HIDSNPALEKLMPHIRGNIGLVFTKEDMSEVRDKIAENKVAAPAKAGALAPCDVIVPAQN TGLGPEKTSFFQALQIPTKISKGSIEILNSVNLVKNGDRVGASEATLLNMLKISPFTYGL IIQQVYDSGTIFDPSILDIKDEDLQARFMKGVTNVACVSLAIGYPTLASVPHLVINGFKN LLAIAAETEITFKEAETVKEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXGNETSLPMELCSNFDADEIKRLGKRFRKLDLDNSGSLSVDE FMTLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEAKLRFAFKIYDMD KDGYISNGELFQVLKMMVGNNLKDAQLQQIVDKTIIHADTDGDGKISFEEFCAIVGTMDV FKKMVVDVMTYITSWEEFSKAAERLYLADPMKCRFVIKYRHCGGQLCMKITDDQVCLQYR SEHAQDVKKLEKLTSQLMRHMASKEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMLSSLVKEHQARQ QSKKEQQEKKKKEAIQATALTHALVDHLNAGVAQAYVNQKKLATETKILQENATHFAKQT TQWLKLVEDFNTALKEIGDVENWSRSIESDMRTISSALEYAYKXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XX---------------------------------------------------------- --------------------------------QTLKSNDSMAQAMKGVTKAMATMNKQLK LPEIQKIMQEFEKQSEIMDMKEEMMNDAIDDAMGDEDDEEESEAVVSQVLDELGIEMADK LTSLPSTGQSAAKTPQGVSDADADLEARLENL---ARYCDFCLGYELENKKTGQKEELVS CGDCGRSGHPTCLQFTANMIISVKKYPWQCIECKSCGLCGTSDNDDQLLFCDDCDRGYHM YCLNPPLSEPPEGSWSCHLCIVEFHG---------------------------------- ------------------------------------------------------------ ----------------------------------YIPAHITKPKEHKRMFLVQLPEKALF AVPRNHKLVAAPLFELYDNSAGYGPIISSLPQALSRFNFSYN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------GILYAFQEQTTEDVVMLNGFGTVVNALGKRVKPYLPQ ICGTILWRLNNKSAKVRQQAADLIARIAIVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLG SILGALKAIVNVIGMTKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGAEFVS AREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVC TTVAIAIVAETCSPFTVLPALMNEYRVPELNVQNGVLKSLSFMFEYIGEMGKDYIYAVSP LLEDALMDRDLVHRQTAMASIQHISLGVYGFGCEDALVHLLNYVWPNVFETSPHVVQAFM GSIEGMRVGLGPSKVLQYTLQGLFHPARKVRDVYWKVYNTVYIGAQDAMIPAYPRIQNDE KNTYIRHELDYTLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------FGKIIDADEVLLFERATFLVISHCQHKPHCDVH RFEKISNIIKQFKLSCSKLAASFQSMEVRNNNFAAYIDIFTSNTYVMVIMSDDSIPSAAT LINIRNVR---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------EIMRELDVDYVLVIFGGLTGYSSDDINKFLWMVRIGGSTDRGEHIKEHDYYTPQ GEFRIDKEGSKTLLNCLMYKMCYYRFGSVYTEQGKPTGYDRVRNAEIGNKDFELDVLEEA YTTEHWLVRIYKVKDLDNRG---------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --EPLEKGLAEDIENEVVKIGWPRKRLGEFFQSKYDWDLLAARSIWAFGPDTTGPNILVD DTLPSEVDKGLLNSVKDSIVQGFQWGTREGPLCDEPIRNVKFKILDAVIAQEPIHRGGGQ VIPTARRVAYSAFLMATPRLMEPYYFVEVQAPADCVSAVYTVLARRRGHVTQDAPI---- --------PAIDSFGFETDLRTHTQGQAFCLSVFHHWQIVPGDPLDKSIEIRPLEPQPAN HLAREFMIKTRRRKGLSEDVSINKFFDDPMLLELAKQDVLLSYGMQEIFSLFDNRGDGKI YAHQLGEVIRAMGYNPTEAEVKKCNDPDARVSFEMFLPILQQISRNKDMSTLEDFVEGFR VFDKEQNGFISSAELRHLLTSLGEKLNDDEVEHLFQGQEDAQGNINYEDFIKSIMSG--- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------NIEIIRNTLY KAYLEDFYKFCQELGGATMEVMCEALAFEADRRAFIITINSFGTELTKDDRAKLYPRCGK LYPDGLAALARADDHE-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------EVCGLKWSPDRQHLASGGNDNRLFVWNANSVNPMQTYTDHLAA VKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQP------------------------- ------------------------------------------------------------ -----------------LVLVGIYYCLTNQGHRFDFGWFLGESSPYMWGNLGIGLSISMS VVGAAWGIYITGASILGGGVKAPRIRTKNLVS---------------------------- ------------------------------------------------------------ -----------MAAGRRLTKELTDNVDESNILLWTGLIVPENPPYNKGAFRIKIEFPAEY PFRPPKITFQTKIYHPNVDEKGQVCLPIISAENWKPATKTDQVIQALVALVNDPEPEHPL RADLAEEYTKDRKKFMKNAEDYTKKHSERRPSEEASLTFPMQCSSLRKNGYVLLKGRPCK IVE--XSKTGKHGHAKVHLVGIDVFTNKKYEDICPSTHNMDVPXXXXVSL------DGYF CLMDDNGETREDLKHTATVWKAMKEEVVKELKQGK------------------------- -------------------QVKISGPFFVAAN-TTHVAVSCYSNHTVHMFDSGKHKFTYK GQGSKPGSLSCPFGVVIDPVGRLLVSDYGNNCVHIVSNQGEFLDHIHVSGPLGLAIN--- ------------------MAAGPIAERNQDATVYVGGLDEKVTEAILWELFLQGGPVVNV HMPKDRITQSHQGYGFVEFMGEEDADYAIKIMNMIKLYGKPIRVNKASAHQKNLDVGANI FIGNLDPEVDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIDAM NGQYLCNRAISISYAFKKDSKGERHG---------------------------------- ------------------------------------------------------------ --------------------KPEVKKVVNPLFEKRPKNFGIGQDIQPKRDLSRFVRWPXY IRIQRQRAVLYKRLKVPPPVNQFNQALDRQTGLQLFKLLDKYRPETSQEKKARLRKRAEE RSKGKDDKPTKRPPVVRSGINTVTTLVEQKKAQLVMIAHDVDPIEIVMFLPALCRKMGVP YCIVLGRVVRRKTSSCLALSHVNPEDRTNLSKVVEAVKTNYTERYEEIRRHWGGGIMSAK SQAKIAKFEKAKAKELAQKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVVIRAIFAR QIFDSRGNPTVEVDLTTDKGLFRAAVPSGASTGIYEALELRDKS-KEYHGKGVGKAVDNV NKTIAPALVLDIANQAAVDKIMFDLDGTENKGNLGANAILGVSLAVCKAAAAHKGVPLYR HLADLAGNKDLILPVPCFNVINGGSHAGNKLAMQEFMLLPTGAKSFSEAMKMGTEIYHHL KSVIKSKYGQDACNVGDEGGFAPNILDNFEGLELLRVAIEKAGYTGKIKIGMDVAASEFC KKYDLDFKNPASNPADWLTSDQLFDVYKGFVEHYPVVSIEDAFDQDDWEAWTKMNAVQLV GDDLLVTNPKRVKTGIETKACNCLLLKVNQIGSVTESIMACKMSQAAGWGVMVSHRSGET EDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEQLGGKVKFAGANFRNP----- ----------------------------------KIAWKVEIEKLDYHHYLPLFFDGLCE TDHPYEFFARQGVHDMLEHGGTKILPVIPQLIIPIKNSLNTRKHTVMCTTLKVLQHLVVS ADMVGEALVPYYRQILPVLNIFKSKNLNSGDGIDYSQQKRENIGDLIQETLEAFERHGGE DAFINIKYMVPTYESCMMNAPPAFESFLLFDGEKKITIQKDTKVPNAALFTVNKEDHTMA NILRIQLLKDPQVLFAGYKIPHPLEAKFVLRVQTTSDYSPQEALTNAITDLISEFSLMEE RFKEAIRERHD--EDHRRKWDREEYEKLAKERIEEEQGKKEPPIRREYLKPREYKVDLDS KLGRSQVITKTTPSSQQGGYFCNVCDCIVKDSINFLDHINGKKHQRNLGMSMRVERSSLD DVKRRFQVNKQKKEEKKKDYDFEERMRELKEEEEKQKAYRKEKRKERKRKAHGDEDDTDM AALMGFSGFGSAKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXYHS QFTNPPKLVGNMALLPLRTQFKGPAFDIIDEAIYYFKANVFFKNFEIKSEADRTLIYITL YISECLKKLQKCQSKNQAGKEMHSLAIQRAFIPGESNFPLNSLYAKPANRQEEETMRAYI QQLRQETGVRVVEKVFDPATDKPSKWWMCFSKRKFMDKSLAAPGQXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX-----------------------DSVSISGNVTGFAVTNHGFH IHATSNFTVGCNSAGGHYNPTSKNHGAPDATERHVGDLGNIVEKDVNMNDNIVTLTGVNS VLNRSIVIHALTDDLGLVNNSGSQTTGNAGARLAC-------MVNFTVDEIREIMDKKKN IRNMSVIAHVDHGKSTLTDSLVSKAGIIAGAKAGETRFTDTRKDEQERCITIKSTAISLY YTLADKDMLNSFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQA IAERIKPVLFMNKMDLALLTLQLEVEDMYQTFQRIVENTNVIIATYGEDGGPMGEIMVDP SKGTVGFGSGLHGWAFTLKQFAEMYASKFKIEESKLMKRLWGDQFYSYERGFTKYILDPI YMVFNTCMPKEEALALAEKLGVKLTSEEKENDQKQLLKIVMRKWLPAGEAMLQMITIHLP SPVTAQRYRMELLYEGPLDDDAALAMKNCDHKGPLMMYVSKMVPTSDKGRFYAFGRVFSG VVSTGLKSRIMGPNFVPVKNIQRTILMMGRYVEPIEDVPCGNICGLVGVDQFLVKTGTIT TYDNAHNLKVMKFSVSPVVRVAVECKNPSDLPKLVEGLKRLSKSDPMVQCMIEESGEHII AGAGELHLEICLKDLEEDHACIPIKVSEPVVSYRETVSEESDRVVLSKSPNKHNRLFMKA QPMPDGLPEDIDKGDVTPRQEMKERARYLAEQHGYDVGEARKIWCFGPDGNGPNIVVDVT KGVQYLNEIKDSVVAGFQWATKEGVLCEENMRGCRFDIHDVTLHADAIHRGGGQIIPTAR RCFYAAVLTAAPRLLEPVYLVEIQCPELAVGGIYGVLNRRRGHVFEEAQTPGTPMFVIKA YLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILVVTDIRKRKGLKENIPELDNYLDKMM LPLSLLRTAVNHPMLVELKNGETYNGHLVSCDNWMNINLREVICTSRDGDRFWRMPECYI RGSTIKYLRIPDEVIDMVKEEVQKQSRGRGDNKGGGRGGPGRGAFGGRGGGRGGMNRGGG GGG--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------YLDPSAEVQKKKYAFKCHRIKEDGVEKIYPVNAIA FHSHHNTFATGGSDGFVNIWDGFNKKRLCQFHRYPTSIASLSFSNDGSLLAIASSYMYEN DTPEDTVFIRRVSDQETKPK---------------------------------------- -------KNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQANLARRAAKEAREAPAQPAPE KPRVEHRKFVKIGRPGYKVTKQRDPETGQQSLLYQIDYPEIVEGINPRHRFMSAYEQKVE PPDRKWQYLLFAAEPYETIAFKVPSREVDKDGKKFWSLWNKETKTFFLQFAFKQDLRGLP VPPRGPAPPPPIMDDDQESYKLWRIRKTVMQLCHDRGYLVTQDELDQTLEQFKQQFGDKP SERRPGRSDLIVLVAHNDDPTDQMFVFFPEETKVGIKTIKTYCQRMQEENISRAIIVVQQ GMTPSAKQSLVDLAPKYILEQFLEAELLVNITEHQLVPEHILMTPEEKKELLERYKLKES QLQRIQAGDPVARYFGLKRGHCVKIIRSSETAGRYITYRLV----DSFGTVVGIDLGTTY SCVGVFKNGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTSNPENTVFDAKRLI GREWTDPSVQHDIKYFPFKLIEKSKKPHIEVNVGEETKVFAAEEISAMVLIKMKETAEAY LGKKVTHAVVTVPAYFNDAQRQATKDAGXIAGLTVMRIINEPTAAAIAYGLDKKEGEKNI LVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKKGKDIRK SNRAVQKLRREVEKAKRTLSSQHQARIEIESFFEGEDFSETITRAKFEELNMDLFRSTMK PVQKVLEDSDLQKNDIDEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEAVAYGAAV QAGVLSGEEDTGDLVLLDVNPLTMGIETVGGVMTKIIQRNTVIPTKKSQIFSTAADNQPT VTIQVFEGERPMTKDNHILGKFDLTGIPPAPRGVPQIEVTFEIDVNGILKVSAEDKGTGN KEKIEIKNDQNRLSPEDIERMINDAEKFADEDKKVKEKVESRNELESYAYSLKNQIGDKE KLGGKLSEEDKETIEKAVQEQIDWLEKNQDAESEEFQTHKKELEGIVQPIMSKLYGDQPP PQEDSEKDELDVGVDDPELEAIKARVREMEEEAEKLKEMQSEVEKQMSMEEKIDADNRSI YCGNVDYGATAEELEAHFHGCGSINRVTILCDKFTGHPKGFAYIEFADKDSIATAVALDE SLFRGRQIKVSAKRTNRPGISTTNRAPR-RARRARSSFGYGGYQPRFRGGGRFRSRRASW YSPY-------------------------------------------------------- KKEKEAELQQRSEMIAHLKDQLQEMKAKTNMEGKYIKKSADVAVAQTQKRCTMEEKTMKD ETESLRNQIEEEKKVNMEVESYLRTHVQDMQSKLDMWMNKYDLDVDAKQKELDLLKMTKA KDLERLQELTKLYHEYEQVVVEDRIEKEKARRKAEQEAEELMAATMLQSWWRGVMVRQGI GAYGKKKKKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNDDLSTAILRNKSRPNRLLVEEAINEDNS VVSLSQGKMDELQLFRGDTVLLKGKRRKETVCIVLSDETVSDEKIRINRCVRNNLRVRLG DVVSVQACPDVKYGKRVHILPIDDTVEGLTGNLFEVYLKPYFLEAYRPVHKGDIFIVRGG MRAVEFKVIETDPSPYCIVAPDTVIHCEGEPVKREEEEEALQAVGYDDIGGCRKQLAQIK EMVELPLRHPQLFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSK LAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQ RAHVVVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEILRIHTKNMKLGEDVDLE QVAAESHGHVGADLAALCSEAALQQIRGKMDLIDLEDDTIDAEVLDSLAVTMEDFRWAMS KSNPSALRETTVEVPNVTWEDVGGLDNVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFY GPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVRDIFDKARQAAPCVLFFD ELDSIAKARGGSVGDGGGAADRVINQLLTEMDGMSNKKNVFIIGATNRPDIIDTAILRPG RLDQLIYIPLPDDKSRVQILKACLRKTPVSKDIDLEYLAKVTHGFSGADLTEICQRACKL AIRQCIESEIRREREMASNPDDYDPVPEMTREHIEEAMKFARRSVTDNDIRKYEMFSQTL QQSRGFGG---------------------------------------------------- ------------------------------------------------------------ -----HDAPVKTVHWIKSPTYSCLMTGSWDKTLKFWDLRSAQPMMTINLPERCYTADVLY PMAVVGTAGRHLIIYQLENQPTEFKRLESPLKYQHRCVSIFTDKKSNAPTGFALGSIEGR VAIHYVNPVNPKDNFTFKCHRAGVQDIYAVNGIAFHPTHGTLSTVGSDGRFSFWDKDART KLKTSDQFDQPLSCCAFNATGNIFAYASSYDWSKGHEGFDPQKMKPHIFLRSCFDELKPS QRKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX---------------------------------------------ATVREENGISYL YLKTIERAAFPRRLWEKVKLSRNMEKAMSQIDEHLIYWPRYIRHKCKQRLLRISQYLIRM RRLRLKRQKKLVPISKKVDRRESRREEKALTAAQIENSIQKELLERLKQGTYGDIYNFPQ HAFEPALECLEEEEESDSESEVEYVAEEEFEESDLSDLE------AQQPRMKSFKIYRYD PDKPGDKPHTQTYQIDLNDCGPMVLDALIKIKNEIDPTLTFRRSCREGICGSCSMNVNGA NTLACLDPIDTSTSKTTSIYPLPHMFVIKDLVPDMNNFYAQYKHIEPYLKRKDMDESNIG KDALFQSPEDRAKLDGMYECILCACCSTSCPSYWWNGDKYLGPAVIMQAYRWIMDSRDDY QTERLSKMRDMWSLFKCHTIMNCTKTCPKGLNPAAAVGEMKKLIQGYDSQGIPKQ----- ----INNLNEKIKKDDLKKSLYAIFSQFGQILDIVAMKSLKMRGQAFVIFKDIGSATNAL RSMQGFPFYDKPMRIQYSKKDSDIIAKMKGTFVVREKKKKADEVSKKKKKQPPAAIPEQP PHHILFLTSLPEETSETMLSVLFKQFPGFKEVRLVPGRHDIAFVEFENEMQAGVAKDALQ GFKITPTNTMKIAFAKKMDSQGKRVVVCDNGTGFVKCGFAGTNFPEHIFPSMVGRPILRS TATINDIEVKDLMVGDEASQLRSMLEVNYPMENGIVKSWEDMIHLYDYTFGSKKLNINPR NCKILLTEPPMNPTKNREKMIEVMFEHYQFDGLYIAIQAVLTLYAQGLLTGVVVDSGDGV THICPVYEGFALPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRIMKEKLCYV GYDIEQEQKLALETTVLVESYTLPDGRVIKVGGERFEAPEALFQPHLINVEKVGVAEMLF NTIQAADIDTRPDFYKHIVLSGGSTMYPGLPSRLEREIKQLYLERVLKGDTEKLSKFKIR IEDPPRRKHMVFLGGAVLADIMKDKDTFWMTRQEYEANGLRVMEKLGVSMAETVGKPIQC RAAVAWEAKKPLTIETIQVDPPKAGEVRIKILHTGVCHTDAYTLDGFDPEGLFPVVLGHE GGGVVESVGEGVTSVQPGDHVIPLYIPQCGECKFCKSPKTNLCGKIRATQGQGFMPDGTS RFTCNGKTLFHFMGCSTFSEYTVVAEISVCKVDAEAALDKICLLGCGVSTGYGAAINTAK VEEGSNCAVWGLGAVGLAAIMGCKKMGAKRIIGVDINAGKFELAKKFGATECINPKDYEK PIQQVLADMTDGGLDFTFECIGNVGTMRAALEACHKGWGVSVIIGVAAAGQEISTRPFQL VTGRVWKGTAFGGWKSRESVPKLVDQYMKKEMMVDEFVTHFKPLDEINAAFDLMHEGQSX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXEPNKISKVVVHPLVLLSVVDHFNRMGKVGNVKRVVGVLLGANRSG VLDVSNSFAVPFDEDDKDRSVWFLDHDYLENMYGMFKKVNAREKIVGWYHTGPKLQQNDV AINELVRRYCPNSVLVIIEAEPKDLGLPTEAYIAVEEVHDDGTPTTKTFEHVPSDIGAEE AEEVGVEHLLRDIKDTTVGTLSQRVTNQLMGVKGLHLQIREVQNYLDRVSSGQLPINHQI IYHLQDVFNLLPDIQLQDFVKAMYVKTNDQHLVIYLASLIRSIIALHNLINNKIQNRDAE KNETKDKDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXRPIPTRRVILNDPSQLPSDYSQTPGG---------------------------- ----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--FSTTSKVA VLGASGGIGQPMSLLLKMNPRITNLALFDIVHTVGVAADLSHCSTRAQVTGFVGPDQLKE SLQGAEVVVIPAGVPRKPGMTRDDLFNTNASIVRDLSDAAAQVCPKAIICIISNPVNSTV PIASEIFKKRGVYDPNRIFGVTTLDAVRSNTFIAEAKDLDVRHVNCPVVGGHSGVTIVPL ISQCTPPVSFPQDEREKLSRRIQNAGTEVVEAKAGAGSATLSMAYAGAKFVNSVIEALSG EEGIVECAFVRSDETEAKYFATPVLLSKNGLEKNLGLGKLIDFEVNLIKEGMDELKANIQ KGEDFVHK---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------RDIRDREIRIYTDAGRICRPLLIVENQRLLLKKRHIDLLKEREYNNYRWQDLV ASGVVEYVDTMEEETIMLAMTPDELQESGDSYCSTNTHCEIHPSMILGVCASIIPFPDHN QSPRNTYQSAMGKQAMGVYITNYHVRMDTLANVLFYPQKPLVATRSMEYLKFRELPAGIN AIVAIASYTGYNQEDSVIMNESAIDRGMFRSVFYRAYKDQESKKGLDQEEIFEKPDRNFV QGMRHAIYEKLDEDGIISPGLRVSGDDVLIGKTITLPDNEDELQGVHKRFTKRDASVFMR RSETGIVDQVMVTINQEGYKFCKIRVRTVKTPQIGDKFASRHGQKGTCGIRYRQEDMPFT CEGITPDVIINPHAIPSRMTIGHLIECLQGKVSANKGDFGDATPFNDTVNVQKISTLLQE YGYQLRGYEILYNGHTGRKLNAQVFLGPTYYQRLKHMVDDKIHSRARGPVQILNRQPMEG RSRDGGLRFGEMERDCQIAHGAAQFLRERLFEASDPYRVHVCNICGLIAIANLRNQTFEC RGCKNKTQISQVRLPYACKLLWQELMSMNIAPRMMF---EAPGGFSFENCRRNAILAKGF TAPTAYKTGTTICGIVYKDGVILGADTRATEDTIVADKNCSKIHYISDNVYCCGAGTAAD TEMTTQMISSQLELHKLNTGRVPRVCTANRMLKQMLFRYQGYISAALVLGGVDVTGPHLY SCYPHGSTDSLPYVTMGSGSLAAMSVFEDRYKPNMEREEGVKLVRDAIAAGIFNDLGSGS NVDICVIMKKTEYIRPYDEANLKGQRQGNYRYKKGTTAILTEQIKKIPFD--XXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXX---TFAAFCYIAALIFSAFLIFFVIYHIIAFDELKTDYKNPIDQ CNSLNPLVLPEYGLHLFFNILFLCAFQFGTFLLNLPLIIYHVHRYVNRPVMSGPGLYDPT TIMNADQLSRAQKEGWIKLAFYLLSFFYYLYSMIYVLVSS-------------------- --------------------------------KTLEHRGFKLNFWDVGGQKSLRSYWRNY FESTDGLIWVVDSADRRRMQDCKQELESLLTEERLAGATLLVFANKQDLPGALPAEEIKK AMDLDKIKTHHWLIIGCSAVTGENLL---------------------------------- ----------------------------------------EEITKFHSDDYIKFLRSIRP DNMSEYGKQMQRFNVGEDCPVFDGLYEFCQLSTGGSVAGAVKLNKQATDIAVNWAGGLHH AKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY GEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEQIFQPVMSKVMEMYQPSVVVLQC GADSLSGDRLGCFNLTLKGHGKCVEFIRKYNLPLLMLGGGGYTIRNVARCWTYETSIALG VEVANELPYNDYFEYYGPDFKLHISPSNMANQNTPEYLDKIKTRLFENLRMLPHAPGVQM QNIPEDAIKDE--------------------------------------------DNSKY ECNICLDTAKDAVVSMCGHLFCWPCLHQWLETRPNRQVCPVCKAGISKEKVVPIYGRGST DQTDPREKLPPRPAGQRSEPENNGPMPGFGF----------------------------- --------------------------------MYALIHKQDQAHEDSIWSCAWARSEKDG TEHIVTGSIDDYVKVWKWADLELRHTLEGHQLGVVSVDINSQGTMAASSSLDAHIRLWDL EAGKQVKAIDAGPVDAWTLCFSPDSRFLATGSHTGKINLFGVESGKSESQLDTRGKFTLS VACSPDGQFIACGAIDGIINIFDLAAGKLLEGHAMPIRGLCFSPDSQLLVTASDDGHIKI YDVQHANLAGTLSGHGSWVLNVAFSPDNAHFVSCSSDKTVKVWDAGSRQC---------- -----------------------------ISDADFDKQQIEIFEDPQSDGWVIRNTMNEL QGMDMVPEPRVIVAAMNACRRINDFSLAVRYLEAVKSKCGPNVSTIWPFVLGEIKPTLDK LGISTPEELGYDKPELALQDVFDIVVRVRGLPWSASQEEVASFLEGCNIVDGVDGVHFTF VRDGRPSGEAYIELESEDDLAKALSKDKHHMGRRYIEVFQSKKSEMDWVVKRSGQRTDAV IRLRGLPFGCSKEEIAHFFTGLEIVPNGISLLHDHQGRTTGDAYVQFASQEAAERAQQKH KERIGHRYIEIFKSSLQEARTTFFSQTGHSIHMRGLPFAATEQDILDFYRPMNPVNVVIH YNKGRASGEADVDFATHEEAQQAMNKDRATMQHRYIELFYKDKDKPTQIRYSNITAAKAV ADAIRTSLGPRGMDKMIQASGGDVTITNDGATILKQMQVLHPTAKMLVELSKAQDVEAGD GTTTVVVVAGSLLDAASKLLNKGIHPTTISEAFQKCAQKSLEILEGMSTPVELSDRESLL KSAATSLNSKVVSQYSNILSPLCVDAILKVIDPAKATNVDLRDIKIVKRLGGTVEDTELV DGLVLDQKTSGYGGPNKVEKAKIGLVQFCISPPKTDMENQVIVSDYSQMDRVLKEERQYI LNIVKQIKKTGCTVLLIQKSILRDAVSDLALHFLAKLKIMVIKDIEREDVEFVCKSVGCK PIASLDHFQPDMLGNAELVEEVQLEGSKVVKITGVANKGRTVSVIVRGSNKLVLEEADRS IHDALCVIRCLVKKKALIAGGGAPEIELAIKLMEYANTLSGMEQYCFRAYAEALEVIPFT LAENAGLNPIATVTELRNKHSQGEITSGINVRKGAITNILEENVVQPLLVSTSAVHLASE TVRCILKIDDVVNCQ--------------------------------------------- ------------------------------------------------------------ --------------------------------------------------VTVIFSTVFK DDDDIIIGKVFMQEFKEGRRRYQQAPQVLFSHKEPPRELQNTEARTGDNIGYITFVLFPR HDARDNTINLIHTLRDYLHYHIKCSKAYIHSRMRAKTSDFLKVLNRARPEPKATEKKTIM LMFCPTCANVLIVEEGPNCYRFACNTCPYIHNVTKRISSRKFPKLKEVDDVLGGTAAWEN VDSTQETCPECSHDRAYFMQIQTRSADEPMTTFYKCCNASCAHRWRKTVFGPLKDADRIF TNLYGRHDWRLKGAMSRGDWYKTKEIILKGQDWIQKEIIKSGLRGRGGAGFPTGMKWTFM NKPSDGRPRYLVVNADEGEPGTCKDREIMRHDPHKLIEGCLIAGAGMGARAAYIYIRGEF YNEASNMQLAINEAYQNGLIGKNSCGSGFDFDIYLHRGAGAYVCGEETALIESIEGKQGK PRLKPPFPADVGVFGCPTTVNNVETIASAPIICRRGGDWFASFGRDRNRDVLMDFDALVA AQTGLGTAAIIVMDKSADVVRCISRLMDFYKHESCGQCTPCREGVCWMAKMMKRFTAGQA RVEEIDMIWEISKQVEGHTICALGDGAAWPVQGLIRHYRPELEKRFKD------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------EGSKMAVRLAGGLQKMVALLQRNNVKFLAITTDCLQILAYGNQESKLIILASGG PGELVRIMRSYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAAGMQALGMHLGHQSTRLVQN CLWTLRNLSDAAAKMEHADNLLQMLTQLLSSSDVNIVTCSAGILSNMTCNNQRNKVTVCQ VGGIEALVRTILQYGEKEDITEPAVCALRHLTSRHPEAEMAQNAVRLHYGLPVLVKLLNL PSRWPLIKAVIGVIRNLALCPANHAPLREHGAIPRIVQLLIRAHQDTQQASNAYIDGVRM EEIEEGTVGALHILAREAHNRAVIRGLNCIPLFVQLLYSPIENIQRVAAGVLCELAADKE GAEIIEQEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRGD S----LQWMIVRNSSCFLVKGSIFSTEPGNLKNKNTFRHNGLVQRRTIGIEAAADGKGVV MVTKRGQRRPAKLYNRVEFKRGPRLALNSIRRTLRKSRYRKDLKMLALRRASAIMRSQKP VVIKKAK---------------------QFTKAAIRTQPKDVLAWSAAYFRAMANGEAPP VKERLEIPVATQRTDTGLTPGLLRVLNKQLGPKKVVPLSLVEEKWRDIAMPKEQFDELVQ VGGFGGDIEWLKFFSLGCSVLGETLTDAMTTVCEILTADPEGGAARIPFPLFKELYTYLA QIDGEISQDHITEVLTYLQYDVDKQEGFVQPRNFLSGDCPKLSXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXX--RLFGKGKPKQPAPNLTDCISNIDSRGESIDKKIGRLDQELAKYRDQMKKMR DGPSKNMVKQKAMRVLKQKRMYEQQRESLMQQSFNLEQTNYGIQTIKDTKTVVDASRTAV KTFQKEYKGLNIDKIEDIQDQLEDLNEQ------VMGRSYGMPDVDDDELEAELDALGDE IALDCDTSYLDDAVSAPSAPTGVPGADSVTNKDGVPVDEFGLPQIPAQ------------ ---NIVCTVNLGCKLDLKKIALHARNAEYNPKRFAAVIMRIRDPRTTALIFSSGKMVCTG AKSEEQAKLAARKYARIVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHGQFSSY EPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKVRQEIYEAFE------------XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------- ------------------------------------------------------------ ---------------------------------------------FKQTERVYDACMEAF DCLPLAALMNQQFLCVHGGLSPEIHTLDDIRKLDRFKEPPAFGPMCDLLWSDPLEDFGNE KTTEHFTHNTVRGCSYFYSYAACCDFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSL ITIFSAPNYLDVYNNKAAILKYENNVMNIRQFNCSPHPYWL------------------- ------------------------------------------------------------ -------------------------------------------------------GGGGR GGFGGGGFGGRGGGRGGGFGGGGGGAPRGRGGMRGGKKVVVEPHRHQGVFIARGKEDALV TLNMVPGETVYGEKKISVEDGKKTEYRAWNPFRSKLAAAILGGVDNIHIKPNTKVLYLGA ASGTTVSHVSDIVGPEGLVYAVEFSHRSGRDLINVAKKRTNIIPIIEDARHPHKYRMLIG MVDTIFADVAQPDQARIVAINAHHFLKNEGFAVISVKANCIDSTAEAEAVFAGEVQKLRT EKFKPKEQITLEPYERDHAVVVAQYRPPPKK----------------------------- ------------------------------------------------------------ ---------------------------LPQLYRNLGLDYDERILPSICNEVLKSVVAKFN ASQLITQRQQVSLLVRKELVDRAQDFNIILDDVAITELTFGKEXAAAVESKQIAQQEAQR AQYVVEIAKQERAQKVVQAEGEAAAAKLIGDAMEKNPGYLKLRKIRAAQQVSRTIAHSK- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GKLTVPAMNVNDSVTKTKFDNLYSCRE SILDALKRTTDVMFGGKQVVVCGYGEVGKGCCQALKGMGAIVMVTEIDPICALQACMDGF RVVKLTEVVRQVDLLITCTGNKNVVTRDHMDR---------------------------- ------------------------------------------------------------ -------------DEYVASLHLPGFDAHLTELTDEQAKYLGLNKAGPFKPNYYRY----- -------------ENDLRKMFEEFGPVFQLNVLRDKVTGQSKGCCFVTFYTRKAALEAQN ALHNIKTMAGMQHPIQMKPADSEKRN-EERKLFIGMLSKKCNENDVRMMFAPFGQIEECT VLREQNGQSKGCAFVTYASRQCAQNAIKAMHHSQTMEGCRFPLVVKFADTQKEKEMKKLQ QIQNTLQMQ------GGCSATYCTHWLDTVKVKMQASPE-YHSSFFCVKDTLKHDGLRGL YQGATTALKAAVVFSSYGLCEEMVRLTGVLASFLLCPTEVIKCRQQTVTKYTLKMDGFRG FFRGL-----------------YEWLQNKLTPEGESRKDLGPRTMFAGGMAGVFNWLVAI PPDVLKSRLQTKEEGFFALYKGVTPVMLRAFPANAACFMGYELAMKFLN----------- ------------------------------------------------------------ ----------------------------------------DDVDVQALVEREQAIHQLES DIMDVNQIFKDLGMLVHEQGEIIDSIETHVEDVHVSQGTEQLQKAKTY------------ -------------------MVNVNKGILVECDPAMKQFLLHLDETNALGSKFVIQDLDET HLFIESASLKTLQDRIDELMDKLNFPIKDKGGKAPSPQEAIQSLRSTEEMLQKKSDFYEK KITEEITTAKKRAALQALKRKKRYEKQLQQIDGTLSTIEFQREALENASTNTEVLRVMGD AAKALKSAHKNMDVDDVHNLMDDVAEQ--------NXISNPVGFGQDMDEDDLMAELEEL EQEALDEKLLDVGQLPSVPTAEEDDLRELEMWAS-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----RLGQLAKWKTAEEVAALIRSLPVEEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKG SELQLPFQACLKVEKFGDLILKATEPQMVLFNLYDDWLKTISSYTAFSRLILILRALHVN NDRTKIILKPDKTTITEPHHIWPTLSDEEWIKIEVQLKDLILADYGKKNNVNVASLTQ-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------TPGSCSLHAYKLTPSGYEWGRQNKDTGN NPKGYLPSHYERVQMLLSDRFLGYFMVPSQASWNFNFMGVRHSPTMKYDL---------- ------------------------TCYTSTRPNLAINKNTKVICQGFTGRQGTLHSSQAI EYGTNMVGGVSPGKGGQTHMNLPVFNSAKEAKDATDCDASVVYVPPALCGKAIIEAIDAE IPLVVVITEGIPQQDMVRVKHRLLRQDKTRIIGPNCPGIIKPGECKLGIMPGHIHKPGKI GVVSRSGTLTYEAVYQTTMVGLGQSLCVGIGGDPFNGTNFIDCLDIFLKDPNTTGIVLIG EIGGQAEERAAEFLKKNNGPKRKPVVGFIAGVTAPPGRRMGHAGAIIAGGKGGAEEKIHS LEDAGVNVTRSPAQMGTALYNEMQDAG-PSSEALKCTLCNERLEDTHFVQCPSVSEHKFC FPCSRESIKRQGAGSEVYCPSGKKCPLVGSTVPWAFMQGEIATILGXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKT CPLLLRVFCNTGRHHPAAEYSRGNTPANELQIYTWMDASLRELTSLVKEVNVDARRKGTF FDFAIVYPDPRAPCYRPREIGTTCAGRRGNDDSVTLQSKRFQIGDYLDIAITPPR----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------VRVELSPMQKKYYKYILTRNFEALNTRG-SNQVSLLNIMMD LKKCCNHPYLFPTAANEAPRLPNQALIKACGKLDLLSKMLQQLYEEGHRVLIFSQMTKML DLLEDFLENEGYKYERIDGGVTGSVRQDAIDRFNAPGAQQFVFLLSTRAGGLGINLATAD IVILYDSDWNPQVDLQAMDRAHRIGQKKQVMVYRFVTENTVEERIVEKAEMKLRLDNVVI QQGRLVDQAANKEVLSMIRHGADQVFASKDSTISDQDIDMILSKGQKKTDEIAEKMSQMG ESSLRSFTLEAPE-SVYQFEGEDYREKQRLGGIGHWIEPPKRERKANYAVDAYFREALRV SEPKAPRAPRPPKQPSVQDFQFYPPRLFEILDKEIYYYRKTIGYKVPKNSDLGAESERLR KEEQKKIDEADQLDEAELQEKEDLLRGFTNWSKRDFNQFIKANEKYGRDDLDAIAKDVEG KTPDEVMEYSAVFWERCNELQDIERIMAQIERGEAKIQRRISIKKALDCKMSRYRAPFHQ LRIQYGTNKGKNYTEEEDRFLVCMLHKLGFDKENVYDELRTQVRQAPQFRFDWFIKSRTA MELQRRCNTLITLIERENLELEEREKAEKKKDGKPSWAEQVEQGEDDALPPGHEDFDEKT GVRKVTEFKYNEEGKKVRVVKIYKVEVKHLAKSIARRKEWKKFGAAAQDPPGPNPANTIE DVFMQFIHGKDT-EDDPLAKIKVTCRICKGDHWTTRCPYKDTLAPENES-PKSGKYVPPS MRDGGNRRGDSMMPDESATIRVTNLSEDTRESDLQELFRPFGTIQRIYLAKDKYTGQSKG FAFINFHRKEDAARAIAGVSGFGYDHLILNVEWAKPSXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXFIQPSSKEKLCTSQWPLLLKNFDKLNVRTAHYTPIPSGCSPLKRPIADYVKSGFINL DKPSNPSSHEVVAWIKRILRVEKTGHSGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYV AIFRLHSAVPDEMRIVKACEMLTGALFQRPPLISAVKRQLRVRTIYDSKLIEYDKDKNLG IWWVSCEAGTYVRTLCVHLGLVLGVGGQMQELRRVRSGIQSEKDDMVTMHDVLDAQWMYD HQQDEAYLRRAIKPLEALLTSHKRIIMKDTAVNAVCYGAKIMLPGVLRYDDGIEINDEIV IITTKGEGVALAVAQMTTAVIATCDHGMVAKIKRVIMERDTYPKKWGLGPVAFKKKQMIK DGTLDKYGRHNEKTPTGWKSSYVDYHLAVKRKHEDPSGEKKKKKKAKKMAEASWDRKKQP RSGQLRSQQAINSAQRRGEEIETTKKFSASQNKQHSAAKNTAKLDRETEQLHHDTVGLTV SRLIQQGRQTKNMTQKELSTRINEKPQVVNDYEAGRAIPNEQVMSKLERALGMKLRGKDK GKPI---MLKPKALTQVLSQANTGGVQSSLLLNNEGALLAFSGYGDKDARVTAAIASNIW AAYERNGKAAFNEDSLQIILMECMEGKVAITRVANLLLCIYAKENVGFGMLKAKVQALAG YLEEPLKQVAA-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------- -----GKYETGQLFLHSVFGYRGVVLFPWVGKVYDRDIASQGSKEVKGKTHTYYQVLIDG RDMPHIRVGTESVTFLSNQENGMLYSIPGLDYVGHEDILPYKTTEKQPVHNHLFDKFLTL DPNYIARDTLREWQDKNHPWLELTEVHRETTESMRITVMPFYIGEVQQTTVYWWRYCIRL ENLDEEIVQLRERHWRIFSLSGTLETVRGRGIIGKEPVFSRAQPAFQYTSHVSLQAPSGH MWGTFKMEREDGSTFEVRIPPFSLESKQED-XXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXMDVFLMIRRRKTTIFMDAKESTTILELKKMVMGITKKSPED MKLFKDNKTLSDYGFTSSTARAQAPASIGLVFREFEALEIAPLSTPPELPDVMKPQESSS SHAQEHLFRYHAVLLRARFDQHKNENPEIANKLLEDGEKEFFLKQHPQPIKFPNSPGGLC YGREAKIPDWGLDMWHPLERAQYPEYFAKREQRKLEYIERYEKQYGK------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------ADFGLARAFGIPVRVYTHEVVTLWYRAPEVLLGSPRYSTPVDIWSIG CIFAEMATKRPLFHGDSEVDQLFRIFRTLTTPTEEVWPGVSSLPDYQLTFPNWKTNTLAQ SVDSKGLDLL-----------------------ASRLFNTLGKVGFGIAIVGGVANSALY NVDGGHRAVIFDRIAGVKPLVVGEGTHFLIPYVQKPYIYDIRTRPRSVPTITGSKDLQNV NITLRILFRPIPDQLPKIFTNLGVDYDERVLPSIVNEVLKSVVAQYDAGELITQRELVSQ KVTQDLTRRAAQFGLVLDDISITHLTFGREFTEAVEQKQVAQQEAEKARFHVEKAEQTKK AAVIRAEGDAKAAELIAKALQDAGDGLVEMRRIEAAEDIAYQLSQSPNVIYLPQGQQTLL SLPMKTIHAEQKVQIPKGVSITVKARKVCVRGPRGKLVREFRHMMVDIKTMSKKELLVEK WFGTRKELAAVRTVCSHIENLIVGVTKGFKYKMRSVYAHFPINVTVTENNTMVMIRNFLG EKFMRDVKMLPGVTCTASTSLKDEFILQGNDIELVSRSAALIQQSTTVKDKDIRKFLDGI YVSEKGHVEEE------------------------------------------------- -----------------LQYKPVVFSNAIQSMIAIIRAMGQLKIDFGHPDRADDARQLFA LAGNAEDGEMTPELATIMKRLWKDSGVQ-------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------QSMMDCLYAKCIPYITDCVMAELEKLGPKYRVALKIAKD PRFQRLTCMHKGTYADDCIVQRVTQHKCYIVAT--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------STDQCI HVCKLGIDKPIKTFQGHTNEVNAIKWDPQGNLLASCSDDMTLKIWSMRQDTCVHNLQAHN KEIYTIKWSPTGPGTNNPNAPLILASASFDSTVRLWDVDRGGCIHTLTKHQEPVYSVAFS PDGKYLASGSFDKCVHIWNVQSGALVHSYRGTGGIFEVCWNYRGDKVGASASDGSVFVLD LRKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XX------------------ELRQIQCQMGVFGQADGSAYIEQGNTKVLAAVYGPHEVRG SKAKHDKVLINCQYSMATFSTGERKHRPRGDRKSIEITAHLKQTFEAAIMTHLYPRSQID IFVEVLQSDGSNYCACVNAATLAITDAGIPMKDLVCASSAGFIDDSPIVDMNYLEESSGA QILLATLAQSDQIAFMQMNSRLHADHLDKVLDTAFQGCRDIYHVINAAIREMAGNYYFAI VGHHDNPVFEMEFVPPNKANEQKKDDHRHLNQFIAHAALDLVDEQMWTTSNMYLKIVDKF NEWFVSAYVTAGRMRFIMLHDTKNEDGIRNYFQDMYEAYIKYSMNPFYEMNASIHSQAFE KKSQVYGRKYLTHQYRYAHTDIQVPDYTAYRKDSLKDARRSFTYVIGAAGCVTTAYTAKV LVQQLLSTMSASADVLALAKIEVKLSDIPEGKNATFKWRGKPLFVRHRTAEEIATEQAVD LGSLRHQEHDNERVQKPEWLIILGVCTHLGCVPVANAGDYGGYYCPCHGSHYDSSGRIRK GPAPLNLEVPEYVFPSEDTVLVGMARQGTRGTDPRKVSGELFTLTYGALVAQLLKDYEGD DEVNKQLDRMGYNIGVRLIEDFLA------------------------------------ ------------------------HSHLSYSNILCGALRGALEMVQMEVDVRVIQDTLRG DNITELRFRFIKRLEDAIPAGED------------------------------------- ------------------------------------------------------------ ------------------------------------------------------YRDLKP ENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVY EMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVN DIKNHKWFSTTDWIAIYQKKV--------------------------------------- ------------------------------------------------------------ ----KKIERQEERLKTHNRDLSMVKMKSMFAIGFAFTALLSMFNSIFDGRIVAKLPFLPI SLIQNLSHRNLIGDDYTDCSFIFLYILCTMSIRQNIQKILGFAPSRAANKQGGGLFGA-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------KIWDRNNLECVQVLTGHTGSVLCLQYDENIIISGSSDSTVRVWSVKTGEMLNTL IHHCEAVLHLRFCDGIMVTCSKDRSIAVWDMQTPTDINLRRVLVGHRAAVNVVDFDQKYI VSASGDRTIKVWNT---------------------------------------------- -----------------------------------------------------EHSGRVF RLQFDEFQIVSSSHDDTILIWDFLNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXSDGETSADRNVEIWKIKKLIKSLEAARGNGTSMISLII PPKDQISRVAKMLADEFGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVIYCGT IVTEEGKEKKVNIDFEPFRPINTSLYLCDNKFHTEALTALLADDNKFGFIVMDGNGALFG TLSGNTREVLHKFTVDLPKKHGRGG----------------------------------- ------------------------------------------NGFNQAIELASEALANVK FIQEKKLIGRYFDEISQDTGKYCFGVDDTLRALEMGSVEILIVWENLDTMRYVLKNHQVD EEKILYLKPEQEKDKTYFTDKETGVEMELVDSQPLLEWFANNYKSFGATLEIITDRSQEG AQFVKGFGGIGGILRYQ------------------------------------------- -------------------------KAKGGGYEDEAVYQNAEVQFLDIHNIHVMRESLRK LKDICYPNIDDAHWLSNVEQSFWLQHIKQIMAGALRIADRVESHKNSVLVHCSDGWDRTA QLTSLAMLMLDPYYRTLKGFEVLIEKEWLSFGHKFAQRIGHGEDKHSDADRSPIFLQFID CVWQMTRQFRNAFEFNEHFLITILDHLYSCLFGTFLCNTEQQRQKEDVRRKTVSLWSFIN SQVEDFTNPLYKHVLFPVASLRHLEVWNAYYIRWNPCMRPQEPLHLRNRELLILKSQLQR RLEELQKEVELRH---RTFIPHVPFDLTQCETVFPKVKAQAEEKTFADACLKRNTDLTPS SGEQAAVLNLVTKINAVLENLVIAPGGFESAQLEEVRQVGSHKKGTMMSGHNVADIVVIL KTLPTMEAVQALGNKILEEMRNTDANEVLTMLPNESGCEISSSEATVKVLITTIPPNFKK LDSELHLDGKLMQGHLAAIRHARWFEENAFHSSVKVLIRLMRDVRSRFEGLQPLTPWIID LLCHFAIMNNPARQPLGVHLAFRRCFQLLAAGFFLPGSAGITDPCESGNVRIHTVMSLEQ QDQVCFTAQTLLRVLSHGGFRQILGLEGNASIATEMSVWEGVAVTPSDKAYEKPEKVVRL IEQYLKENNLNRTLSCLQEESGISLNTVDSVDSFVSDINNGHWDTVLQVIQSLKLPDQKL IDLYEQIVLELIELRELGAARTLLRQTDPMIMMKQQQPDRYLRLENIMARSFFDPREAYP EGQTKERRRGAIAQALAGEVNVVPPSRLMALLGQALKWQQHQGLLPPG------------ -----EKYPTQLSKSIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLK YQAQDNFMMMDDAVLCMCFSRDSEMLATGGQDGKIKVWKMQTGQCLRRFERAHSKGVTSI LFSKDNGQLLSCSFDQTIRIHGLKSGKTLKEFRGHTSFVNDAVFSPD------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------MAQAANKIPQLIDFATPKLKTFWKYARVELKPPGEFPQVA QGFNSVLTAKSGAWKKLTVKEAGLVALECVFWFYIGECIGKGSLIGYQIPGATHFALH-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------VFQECLTYDGEMDYKTYLDFVLALENKREPEALQYLFRILDVQ GKGHLNVFDLNYFFRAIQEQMRLHGQEPVNFQDLQNDIFDMVRPADPYKISLQDLINCG- --TVMSILIDLNLFWTYENREXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXX------------------------------------------------------- --------------------------------PQFALVMRSGDMLNVRAEDLVVGDVISV KFGDRVPADIRVISAHGFKVDNSSLTGESEPCSRSPDFTNENPLETKNLAFFSTNAVEGT CQGLVVSTGDRTVMGRIANLASGLEMGDTPIAKEIAHFIHIITGVAVFLGVSFFIIAFIL GYYWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTI CSDKTGTLTQNRMTVAHMWFDNHIFEADTSDDQSNAAYDRDSPTWMSLARIAMLCNRAEF KTGQDGVPVLKRECNGDASESALLKCVELSIGNVTEFRKANAKVCEIPFNSTNKYQVSVH KDDPRFLLVMKGAPERILDRCTTIMVGGEEKALSDEWRDNFNRAYMEMGGLGERVLGFCD YLLPADQFPPDYPFDSDEENFPLTGLRFVGLMSMIDPPRANVPDAVSKCRSAGIKVVMVT GDHPITAKAIAKGVGIISEGSETVEDIAARMGVPVSEIDPRQAKACVVHGSDLRDMTPAQ IDEVLSVHPEIVFARTSPQQKLIIVEGCQRQGQIVAVTGDGVNDSPALKKADIGVAMGIA GSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLLFILAD VPLPLGTITILCIDLGTDLVPAISLAYEQAESDIMKRTPRDPLHDKLVNHRLIGMAYGQI GMIQASAGFFVYFVILCENGFWPSRLLGIRKSWDSKAVNDLEDSYGQEWTYAQRKVLEYT CHTAFFVSIVVVQWADLMICKTRRNSIIHQGMLNHHMTFGLFFETALAAFLSYCPGLDKG LRMYPLRFTWWFIPFPFSLAIFIYDECRKYLLRRNPGGWIELETYYSFQGLSKGKKAAAS LAAGAVGLGVALQDLELHAPNYPWSHKGYFQAFDHASIRRGYFVYKQVCAACHSMKYMCY RNLVNVIMTEEEAKTEAEEIQVVDGPNDEGNMFERPGKLSDRFPHPYANDEAAKAANNGA LPPDLNFITLARHNGENYVFSLLTGYCDPPEGVELQEGMHYNPYFAGGSIGMARALYNEI LDYDDGTPATASQLGKDVVTFLAWAAEPEHDTRKRWGLKFIMIMLIGVSYYYKRHKWTVL ------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSDVGS DDEQGPYLGEYEGERNERDERHGHGKATLP--XTYEGMYENGKRNGQGTYRFKNGARYIG EWLKNKKHGQGMFIYPDGSKYEGSWVEDQRCGFGKYFYANADSYEGEWQNHVRNGQGTYT YADTGTKYVGTWQEG--------------------------------------------- -------------------------------------------------------RGYIA MLAVDKNYRRRRIGSHLVKKAIRAMMADDCDEVVLETEITNRAALHLYENLGFVRDKRLF RYYLNGVDALRLKLWLK------------------------------------------- ---------LYQKDDAQKGKFAFTTEEYDMFEVCFQSKMLDNSQGGNREVMLNMKHGVEA KDYQNLAKAEKLKPMEVELKKLEDLSESIVNDFAYMRAREEEMRDTNESTHSRVLYFSIF SMLCLLALATWQVLYLRRFFKAKKLIE--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------NLDLLTTFLNVLPPLSTQDSVEYQIDEVYDLSGVGIVVGGALARGTI KESEKLLVGPSDSGDFTEVTVQSIQRNRLPCRIATAGQAATLALGHFHIRRGMVIVSPLS QPVACMEFEAKVYLLYHSSYICKGFQTVIHVGNVRQTAIIVKMNKGCVKTNEKAHVLFRF FSRPEFIRPGSRLLFREGRSKGMGEITRIYPY---------------------------- ------------------------------------------------------------ ------------------------------FRGHTKQVTCLCMSMDGLLVSGSNDTNVKL WDVIRTIP-HKSIITNL------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---VRFKRWESERILSFVPPDGNFRLISYHIGSQNMVAIPVYLKHSISFREGCAGRLDLT VGPKQTMGKVVENVIVEVPFSKSVLNVTLTPTQGKYSFDPVNKVMTW----IDPTKLPNI RGSINMQTGAPPPDSNPVISVQFTISQMAVSGIKVNRLDMYGEKYKPFKGVKYVTKAGKF QVRT-------------------------------------------------------- --------------RKWKDILELKVAEIDKEISDLSNFKEECEKALEAKNLPEEVNLENL TTREGRQDIDVVEDEVEDQLKKEKEVISGVKRQLQQRIDESFEQICLLQEARQQLLHDLQ DKNVALDIDVEQYNLTEESPGISYKPDPCRVPKGSTTPQNWEDFSRYNVDRADAEMEASR RLREAIHHTLQQTENDLQAQQNATDYAIRKRQHEMKRAIDELKWQKQQTEEEIADIEEEI RRLNDAIRAKINPSKLAQTRLENRTYRPGVELCRDNVQYGLVDEVHQLDTTKKSLEEKLK QAQHVLDGLEQNLHRINEDLQCKMNSLALDDQCSKSRERLERNMTLTGI-SLRDVMTNLI PEHQKAVKEFRTKHGADVVGQVTVDMMYGGMRGIKGMVWETSVLDPDEGIRFRGQSIPEC QQSLTKAPGGEEPLPEALYWLLCTGQTPTEEQTKGLSKEWAGRADLPSHVVTMLNNFPSN LHPMSQFIAAIAACNSESHFAKAYSDGVKKSLYWEYVYEDAMDLIAKLPTIAAIIYRNLY RDGTSVGAIDPDKDWSANFTSMLGYEDPTFTELMRLYLTIHSDHEGGNVSAHTSHLVGSA LSDPYLS----------------------------------------------------- ------------------------------------------------------------ -------------------------------------------------------MPWQP PKTEKCEICSKSVYAQERQEAGNKIYHKLCFKCSQCKMSLKLNSYAQADGILYCLKHYQE NVVAKNTQ-DQLFVHRDTKENNPDIKFEFTLENMKRAEAIIGNYPKGFEKGAMMPLLDLA QRQYGWLPIAAMHYVADMIKVPRMRVYEVATFYTMYNRQPVGKYHVQICTCTPCLLGGAG SDVILDALKKNLGITPGHTTKDNMFTLSEVECLGACVNAPMIQINDDYYEDLEPHDIDRI LNDIKAGKEPKPGPQSGK--RFSCEPAGGLTSLTEPPPGPG-------MQKYEKLEKIGE GTYGTVFKAKNRESQEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLYDVLHS EKKL-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GDARFFQHNGPRSGINYPLKG EC-SMPVEYCEFHPNYEKCKQWMEKNLPSEMQQLLVKRQTRGGRGNVKAKKKAEPQRVGL SRASRGKRKYVTVVTGLASYEIDLKVAGKFFATKFSCGASVTGEDELVIQGDVKDDLFDI ITEKWPQIDEDNIDDLGDQKR--------------------------------------- --------------------------------GKLQTLDILLRQLKAGTHRVLIFTQMTK MLDVLEGFLNYHGHRYLRLDGTTKVEQRQALMDRFNMDKRIFVFILSTRSGGLGINLTGA DTVVFYDSDWNPTMDAQAQDRCHRIGQTRDVHIYRLISERTVEENILKKA---------- -----------------------------MSLETVPKDLRNLRACLLCSLIKTFDQFEYD GCDNCEDYLHMKHNRDAVYDCTSSNFDGMISMMSPQDSWVAKWQRTNRFAKGVYAISVNG RLPQGLVRELKSKGITYRPRDTSMPRFVPYLSKEKEDELRNIANAITAPGKGILAADEST GTMGKRLTNINVENTEENRRLYRQLLFTSFKTAISGVILFHETLYQKADDGTPFVKILQD QGVIPGIKVDKGVVPLAGTDGETTTQGLDGLSERCAQYKKDGCGFAKWRCVLKISSHTPS YQSMLENANVLARYASICQQNGLVPIVEPEVLPDGDHDLETAQRITEQVLAFQYKALADH NVFLEGTLLKPNMVTAGQSCAKKYTPEQVALATVTTLQRTVPAAVAGVVF---------- ---------KPWALTFSYGRALQASALAAWQGKPENTKAGQGELMKRAKANGQAALGQYG GGTAGAGGKSLFVADHKY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------FRERVVPLAVGYYLGEVHDDEDDEDDEDDEIILLK DGTDQTQGKPQLISNVNACQVVVDAVRTTLGPRGMDKLVVDNGGKATISNDGATIMKLLD IVHPAAKTLVDIAKSQDAEVGDGTTSVVLLAGEFLKQCKPFIEDGVHPQVIIRAFRKATQ LAVSKIKEIAVKTKKDKKEQRQLLQKCAATALSSKLVARQKEFFANMVVDAVMQLDELLQ LNMIGIKKVQGGALEDSKLIGGVAFKKTFSYAGFEMQPKTYKNPKIALLNIELELKSEKE NAEIRVDNVEEYQSIVDAEWKILYDKLDALHACGAKVILSKLPIGDVATQYFADRDMFCA GRVTDEDLKRTMKACGGAIQTTTSKMTLGTCDLFEEVQIGNDRYNLFTGCAAAKTCTLIL RGGAEQFIEETERSLHDAIMIVRRAIKNDAVVAGGGAIEMELSKYLRDYSRTVPGKEQLL IGAMAKALEIIPRQLCDNAGFDATNILNKLRQKHAGMWYGVDITTEDIADNFLACVWEPS IVKINVLTAASEATCLVLSVDETIKNPKSGGDPPGMGRGRGRP-XXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------LQCIDISMILAEA IRRTHNGESVSYLFNQVPILMCRFYEHKFPEIEDVVMVTVRSIAEMGAYVHLLEYNNIEG MILLSELSRRRIRSINKLIRIGRNECVVVIRVDKEKGYIDLSKRRVSAEEVIKCEEKFAK AKCVNSILRHVGELLKYETDEQLEELYTKTAWHFDRKYGKPGASYEAFKHAVSNPEILDE CGLNEETMDVLLSEIQRKLTPTQVKIRADIEVACYNYEGIDAVKSALKAGLSESTEEMPI KINLIAPPLYVVTTQTLERQEGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMRPLTEEETKTFFA KLSKYIGENIKLLLDRPDGSYCFRLHRDRVYYCSEELMKKASEIGRDNLLSFGTCLGKFT KKQKFRLHITALEYLAPYAKYKVWLKPSAEQQFLYGHHVMKSGLGRITDDTPEYQGMIVY SMNDLPLGFGVSAKSTQECRHADPMAIVCFHQADIGEYIRNEDKLASDRKFFVGGNWKMN GNKQSIDGIVKFLNEGNANTEVVVSPPTIYLDYVRQHLLGVAAQNCYKVEKGAFTGDISP AMIKDVGCEWAILGHSERRHVFGESDQLIGEKVAHGLASGLYLIPCIGEKLEEREAGKTE EVVFRQTKASDWSRVVLAYEPVWAIGTGKTASPEQAQEVHEKLRQWLAKNVSADVAKSVR ILYGGSVTPDNCRELAKKPDIDGFLVGGASLKPDFVKIINAREREGLLDPAWEKQQKKTF TAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGEQLPKPDRGRMRFHKIANVNKAL EFIESKGVKLVSIGAEEIVDGNLKMTLGMIWTIIVQNFHMSFKDGLAFCALIHRHRPELL EYDTLGKDRPLENLNLAFDIAEKYLDIPRMLDAEDMVNSVKPDERSVMAYVSSYYHAFSG AQQAETAANRICKVLKVNQENERLMEEYERLASDLLEWIRRTTPWLENRVTDNTLPGTQH KLEEFRDYRRAHKPPKLADKAKLETTFNTLQTRLRLSNRPAYLPTEGKMVSDIANAWKGL EKAEKGFEEWLLSELQRLERLDHLAKKFKHKCDIHEEWAFGKEDMLQAQDFKRCKLNELK ALKKKHEAFESDLAAHQDRVEQIAAIAQELNALDYHDSPAVNARCQRICDHWDLLGTLTQ QRRNALDEAEKILERIDQLHLEFAKRAAPFNNWMDGAKEDLVDMFIVHTVEEIQGLMDAH EQFKNTLGEADKEFQSIMGLVQEIQRLAHQFGIQNALDNPYSTLSAQDIAHKWNDVKQLV PQRDSTLHSELIRQQNNERLRRQFAQKANVVGQWVERHLDAVASVGVQKGSLEDHLNKLK GLEKEIMGYKPNIDELERYNEEVQEAMIFENRHTVYTMETLRVGWEQLLTSVARAINEVE NQILTRDSKGITNEQMDEFRKSFFHFDKTRSRRLEPKEFKACLVSLGYNIKDNRQGEADF QRIMSIVDSNHAGYVTFDAFVDFMTRETTDTDTAEQVMQSFRILAGDKPYITPDVLRREL PPDQAEYCIQRMAPYTGPDAVHGALDYSSFSTALYGESDLNKLSIDSLDLKDKRVLIRVD FNVPLKGTEITNNQRIVAALPTVKHALDHGAKSVVLMSHLGRPDGRRQDKFSLKPVADAL KGLLGKEITFLSDCVGAEVEAACSNPSAGSVILLENLRFHIEEEGKGVDEGGKKVKADPK KVEEFRASLSKLGDVYVNDAFGTAH----------------------------------- ----------------------------------------------EIGNSLYDEEGAKI ITQLMEKAKKNNVQIHLPVDFVTGDKFAEDAAVGKADKKSGIPAGHMGLDVGPETTVKFT EVVGRAKTIVWNGPAGVFEMEAFAHGTKGLMDAVVHATQKGATSIIGGGDTATCCAKWKT EDKVSHVSTGGGASLELLEGKTLPGVAALSNAMTGIPPKTWQPPNATIETTMGSVVIELY WKHAPNTCRNFAELARRGYYNGVKFHRIIKDFMIQGGDPTGTGRGGASIYGKQFDDEISD ELKHTGAGILSMANSGPNTNGSQFFITLAPTQWLDGKHTIFGRVQSGMQVVNRIGMVETD TNDKPTEDIKITRRRSRSRESRSDRDRQRRQKPYKYWDVPPPGFEHITPLQYKAMQAAIP FAGSAISRQARRLYVGNIPFGVTEEMMMDFFNGQMKVAALAQAEGNPVIACQVNLDKNFA FLEFRSVDECTQAMAFDGINFQGQSLKIRRPRDYQPLPGIPETPSIGVVSTVVQDSPHKI FIGGLPNYLNEDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDQACAGLNGMQLG DKKLIVQRASVGAKNAQ-LPVQLQIPGLNIQQVPTEVLCLMNMVAPEDLEDEEEYEDIIE DVKEECGKYGIVKSIEIPRPIKGVEVPGCGKIFIEFNSMIDCQKAQSALTGRKFNNRVVV TSYFDPDRYHRREFFLPMFDRVLVERFAVETQTKSGIYIPEKAQGKVLEATIVAVGPGAR KEDGTHMKPAVXVGEKVLLPEYGGTKVVIEEKDYFLFRDGDILGKFERLKQQIPDIKTTL DIVRHMKTKKDAMETHFQMSDQLYVVASIPPTDKVCLWLGANVMLEYNLGDAEALLDKNA ATKSLIQVDEDLGVIRDQTTTIEVNMARVYNWDVKRRQ---------------------- -------------------KEFLDKISEFQKIVGTFLKLVDDVAKEVENEKMKAIGSRNL LKSVSKQREAQQQQLQALITEKKMQLERLRIQHEALQKEEQ------------------- ------------------------------------------------------------ --------------------------------------------------GISGPMRLYV GSLHFNITEEMLKGIFEPFGKIDDIKLMRNHETGRSQGYGFITFHNSDDAKRALEQLNGF ELAGRPMKVGHVTERTGEGGMLDSDEMDRAGVDLGATGRLQLMAKLAEGTGFQLPAAATN ALQMAP----------------------------------------------------ST GTGNVVGQQPQQQQQQQA------------------VPLPSYHQLFPDAQRATQLLIPST ------------------------------------------------------------ -------------------------------------FYVIDQGEVDVYVNNEYISTIGE GGSFGELALIYGTPRAATIKAKTDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLSKVSIL DSLDKWERLTIADALESVQYDDGHEIVRQGEPGDDFFIITEGSARVLQRRAENE------ ------------------------------------------------------------ -----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------ELQYKQTK VAVTSLSFLSGDVNNFVVGSEEGAVYNSCRHGSKAGIQEMFEGHQGPITGIDCHNVPGHI DFSQYFVTSSFDWTVKLWNIKENKPFHSFEDNSDYVYDVRWSPVHPAVFATVDGMGRLDL WNLNNDTEVPTASTINVAVNKCRWHQSGQTIAVGDDLGRIHIYDVGEQLAHPKTDEWGRF VHTLQGLKNQQPDADEDQ------------------------------------------ ----------------------------------KKVVCHFYRDSTFRCKIVDKHMALLA PKHLETKFVKINAEKVPFLIERLRIKVLPTICLAKDGKTVDYVVGFDDLGGSDEFSTEML EWRIAQAAVINYSGDLLTPPSGGFKKKTIRGRDDEDKTVVLTGHGGYDKLKIEQRPKPNA GEVLVHVKASGINFAELMAREGLYDRAPKVPCVLGLEGSGVIEEVGDGVTNLKVGDRVMA INGLWTEYKAHCFIMPENMTFAEAAAIPVNYITAH------------------------- ------------------------------------------------------DIVLDP LSGHDSVKGFKLLKPMGRIIHFGAANIVTGTTRNLWQAAKTWWATSWYSPLGLMPENKIV AGYHLGYLVCAEELLDLYRQGKIKPVIDSQWSFDEIGEAMSRMHERKNIGKVIICPE-MS RKQTPSDFLKLIIGRPVVVKLNSGVDYRGVLACLDGYMNIALEQTEEYVNGQLKNKYGDA FIRGNNVLYISTQKRRV------------------------------------------- -----------------------QKPPKMKFVSEIWHPNIDKTGDVCISILHDPGEDKYG YERPEERWLPIHTVETILVSVISMLADPNDESPANIDAAKEWRESKEEFKKKVARCVRKS QEATVRVPNAVVRQNLADFGRYVGECMPAWVQQVQVTSGDELEILVHPEGIIQVLTFMKD HHNAQFGNVADICAVDVPTRQNRFEIVYNLLSLRYNSRIRIKTYTDELTPLPSSNGVFKA ADWYEREIWDMFGVFFTNHPDLRRILTDYGFEGHPFRKDFPLQGYVELRYDEEVKRIVAE PIEMAQEFRKFEYSSPWESFHEHRQ----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------GPNVSDTEIGHAGTCQWKICGLYPNSTLGVYFEVVNQHNAPIPQGG RGYIQFITTYQHSSGQKRVRVTTVARNWVDASINTQHIAAGFDQEAAAVLMGRIAISRAE TDDGPDVLRWLDRMLIRLCQKFGDYHKDDPNSFRFSEQFTLYPQFMFHLRRSQFLQVFNN SPDETSYYRHMLNKEDLTQS---------------------------------------- ------------------------------------------------------------ -----------------------------------------------MSNLTHEQQLKLI SDLEIEMMADMYNRMTTACQKKCVPPKYKDSELNKGEAVCLDRCVAKYLDVHDRIGKKLT SMSMQDEETMKKLQ-AQTPAVIHKVIMVGSGGVGKSALTLQFMYDEXXEDYEPTKADSYR KKVVLDGEEVQIDILDDYAAIRDNYFRSGEGFLCVFSITEQESFQATAEFREQILRVKND EHIPFLLVGNKCDLEDKRQVTAEEAGSRSEQWNVPYVETSAKTRANVDK----------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------HIIQVSTYQMVILMLFNQ TEKRTYEELKSETDIPERDLIRALQSLALGKITQRILTKEPKSKEIEKNDIFMMNDQFTS KLYRVKIQTVAAKGESEPERKETRNKVDEDRKHEIEAAIVRIMKAR------VLVAEVTE QLKARFLPSPVVIKKRIEGLIERDYLARTPEDRKIYTYVADRIDVFPSRMAQTLMKAKLK GAQKGHSLLKKKSDALMVRFRQILKKIIETKQLMGDVMKEAAFSLAEAKFTTGDFNHLVI QNVNKAQIKVRAKKDNVAG----------------------------------------- -------------LDEAIKITNRRVNAIEHVIIPRIERTLSYITSELDERERDEFFRLKK IQKKKQERVGGSLLDQYDEDLLF-------------AYSLLYSVAKGDVFGRDQPIKMVL LDIETMMGVLNGVVMELNDCALPLLSEITPTFNVNDAFKDVDVAMLVGAMPRREGMERKD LLQANVRIFKQQGQALDQFAKKTVKVVVVGNPANTNAFICKKYAPSIPPQNFSCLTRLDQ NRAKSQIAGRGDVKNVIIWGNHSSTQFPDVRHATVVFEAVKDDNWLKNEFISTVQKRGAA VIAARKLSSAMSAAKATCDHFHDWWHGTSDGEWVSMGVSSDGYGIEPGLIYSFPVKIDHS YEIVQGLAIDDFTREKLDSTLKELIEERDSALEACXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXX-------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------QVEQDCAVSEANPHIVNIGKLVEDMENKIRNTLNEIY FGKTQDILNGLRSVTSLARDILKTDLAAALKSRQQ----FDDLDEPLDEVEEGDNIEVLP ANEKVEPHNRMTTPYMTKYERARILGTRALQIAMCAPVMVELEGETDPLQIAMKE----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------SDRFLNMGGPLAMGLGVVFVSSIGTWFLPASTALGAGMYSIAVY GGLVLFGMFLLYDTQKIIKRAETHPVYAAQPYDPIDNSTGIFLDTINIFMRIAMILAGGG GRRK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------FSSSTDGQVLWWDIRKLT EPTEKLYLDPTKKQDPTKAQGAMCLEYEPTMPTKFMVGTEQGTVMSCNRKAKTPGEKIVA VYPGHHGPVYALQRNPFFPKNFLTVGDWTARIWSEDIRESSIMWTKYHMSYLTDGCWSPV RPGVFYSTK------------------------DEPLHSLRVQDAGRLIATGSSSGTATL LELSDGLCTLQRNEKTVVTAMFDRETRREKILEARHREMKLKERTKSQWEELVALVGPIA KPLASKKLAKRLYKCIKKAIRKGVREVQKFVRKGEKGIVVFAGDTNPIDVLSHMPVVCEE KDLAYCYTPSKEDLGAACGSRRPTCMVLIKRAEDYVDTYDQCLEEVKSLPLPIMPVENLE EEGLPKNPNLDLAQWRFLLTTDKHRNDESIKTQLSQAIKADNMAPFYEELCTDMGWKVDQ ALLAEMKQANQENLQKLDDAVEDAEKNLGETEVRDFMLEKAEYLSKTGAKEETLSQFRKL GEKVVTLGFKLDMTFHQIRIGLFYMDHDLITRNLEKAQSLIDEGGDWDRRNRLKVYKGVY CMAIRDFKTAAGLFLDTVATFTSYELMTYQSFVTYTVLCSVIALERADVLKKVVRGSEIL EVLHGLPNVRQYLFSLHNCHYGDFFKSLAEVEQMMKYDRYLSPHYRYYVREMRIKAYAQL LESYRSLTLEYMAKAFDVSMDFIDQELSRFIAQGRLHCKIDKVGGIVETNRPDSKNWQYQ GTIKHGDILLNRIQKLSRVINI-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------VAPPNYFNITLKDSLMY TTGMGGVVGLGVISPNPAFSTMVTTFGLAGIVGYHTVWGVTPALHSPLMSVTNAISGITA VGGLWLMGGKYMPTDTPQTLAAVAAFISSINIGGGFLVTQRMLDMFRRPTDPPEYNYLYG IPLAALLTGYGATYHGGYPDIHSMTYLAASLCCVGALTGLSSQKTSRLGNALGMMGVSSG LIATLGILKPSPELLTQMGALCFGGMGIGATMAKRMEVTDLPQMVALFHSLVGMAAVVTC VANFMVEQPHFATDPAADVIKTVTFLGTFIGGITFTGSLVAFGKLQGVLKSDPLLLPGRH MMNLGMALANVGALAWYLGTDSEICLSMLGATTALSSIMGVTLTAAIGGADMPVVITVLN SYSGWALCAEGFMLNNSLMTIVGALIGSSGAILSYIMCVAMNRSLPNVILGGFGTSSYAG GEAMKIEGTHTEIFADGTVELMAEAQNIMIVPGYGLCVAKAQYPIAELVELLTSKGKTVR FGIHPVAGRMPGQLNVLLAEAGVPYDIVHEMEEINDDMPEVDLTLVIGANDTVNSAAEED PNSIIAGMPVIRVWLSNQVIVMKRTLGVGYAAVDNPIFFKENTSMLLGDAKKTCDSLL-- ----RPDAIPGCPPGLEYLTQVDQILVHQSVNLLEAFTSLECQCSFEVKNAAGQKIFQAG EESGFCTRQCCGAQRGFIMHVADNFGSEVMRAERDFKCCACCSWCACCAHLIAVEXPVGN VYEQWHFRFIKPCFEIQTAILKLEGPWCICECPCC--DVDFEVHTNKVGHVIKQWSGGVK EIFTEA-------------KMKACMFGACFLIDFMFFEHQQ-XXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXGKKLTEATEENCEVCVKFIGKFIDSLSSVEKAFRKLC KNTKKDDHRLCYYVGGLEESATGMVGTLTQPISWGVPADKVCMKLYRKDAQICDLKYDKQ IDFANVNLKKLKVGDLKKILSDWEEQCKGCTEKSDFVKRIEELMVKYAPEAAXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX----------------------EKPLYVYYCLCGQMSLILDCPIE KLPMRRRDNARVIDSAKHAHKLTCEPDETTYIKRPEGIEKQFRQKCKRCGLFLYYRHKNQ VTFIVSGALKMSSEVKADVYSQIAKPKKVMVTKHTKNMGKFSSVTVSTVDEEEEEIEAKE IADSYAANARVIEKQLIRKGLSKRKMMEEAQAEAKRMRPKGTLID---------AAGQRR NYADMAFTFASPSSVKIKQVDVPSFSGSFGILPDHVPLLAVLKPGVVTVTEEDGNSKRYF VSSGSVTINDDSSVQILAEEAVTVDQLDAQAIREGLSKASQEVGSDAVKAEAQIAYDCYE AMQKALE------------------------GHGLDKRKRFKYLTSELRLTEAIHEPHIC EDILKYNVHAERKGSNRYAKGQSETMSTLHGLVNKGVKVELGIPYELWDQPSAEVSKMHR SCFLLAENHEEDIEEWYYNHQEDLMNYLCEKRYLPGK--VFAPTDVTSADNVQSAITAKD KFGRLDMAVNCAGIGVAFVTYNKNKDRVHSLEDFQKVLHVNTAGTFNVIRLATQVMAHNE PNADGQRGVIVNTSSVAAFDGQRGQAAYSASKGAIVGMTLPISRDLASLGIRVNTIAPGL FRTPLLASLPEKVQNFLASTIPYPSRLGNPDEFAHAVQFLIESPYMNGHTLRIDAALRKR DFHFRVHGRNSNAQSQLSRDYPVIDHTYDAVVVGAGGAGLRAAFGLAKEGFKTACVTKLF PTRSHTVAAQGGINAALGNAEADCWEYHFYDTVKGSDWLGDQDAIQYMCEEAPRAVIELE NYGMPFSRMDNGKIYQRAFGGQSLDYGRGGQAHRACCVADRTGHSMLHTLYGRSLMYDTD YFLEYFACDLMMQGGRCNGVTAISLEDGTIHRIFAKNTVIATGGYGRAYFSCTGAHTCTG DGTALLSRAGLANQDMEFVQFHPTGIYGAGCLITEGCRGEGGYLINSEGERFMERYAPTA KDLASRDVVSRAMTVEIREGRGVGKEKDHCYLQLSHLPPETLEKNLPGIMETAHVFAGVD ARRDPIPVLPTVHYNMGGVPTNYLGQVIQYDKKDEVVPGLYGAGEAACVSVHGANRLGAN SLLDLVIFGRACAHHIRDTCNPGDAIPDSGANAGEETVANIDFLLNNPGKTKTADLRRRL QKNMQTNAAVFRDGPTLQEGCRQMHSLWEEMDLHVSDKGMVWNSDLIETLELQNLMMNSS ATVFSAEARKESRGAQAREDYPDRIDEYDYTKPIEGQTKVPIEKHWRKHSLVFVDHNNGK VKLEYRPVVDKVLDNSKIDTIPPKIRAY-------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------AVAATLNNLAVLYGKR GKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEQYYQRALEIYE TKLGQDDPNVAKTKNNLASAYLKQGKYKQ------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------QSGMSMGGARHAADIRADDMSKEG QSVIGLQAGSNKGASQSGMSMGGARHAADIRADDMSKEGQSVIGLQAGSNKGASQSGMSM GGVRHVADIRADDMSEGQNVIGLQMGSNKGASQSGMSMGAQRHAGDIRADQMEGQSTIGL QMGSNKGASQSGMSMGGQRHAGDIRSDPMTSQGVINLQYGSNQGDTQSGMSMGGRRDI-- ETHSFGIVPITVHAWNRDRTQLAIPNNHEVHIYKKGWDLLSTLTEHVQRVTGIDWAANSN RIVTCGADRNAYVWPTLVILRINRAATCVKWSPQENKFAVGSGARLISVCYFEQENDWWV SKHVKKPLRSTVTSLDWHPNNILLACGSSDFKARVFSAYIKEVEPKPEATPWGKKMTFGQ VMQEFSNGGGWVHSVAFSGSGNRLAWVGHDSSVSVVDATTKTEHLPFLSCIWLTENSLVV AGHDCCPMLFSFSG-NVSFVARLEEQKFSAMKHFKSLDSRATGLNFTHQNTITQVGLHSG NKSQVSKFSTTGVDGQMCVWD------------------------------------SGL GKSTLVNSLFHSDIYGDDHPGPSLRIRKTVQVEESKVLLKEGGVNLRLNIIDTPGFGDSV NNTNCWEPVLKYMDSKYSEYLVAESRVHRITVPDNRVHCCLYFISPNGHGLTPLDVEFMK SIHLKVNILPIIAKADTMTQAE----------------------HDDEETKITKELKGRV PFAVIGSSTVVDSQGRRVRGRAYPWGVVEVESLEHNDFVCLRNMLTRTHMQDLKDVTNNV LYESFRLSKL-------------------------------------------------- --------------------------------------MARRYDTRTTIFSPEGRLYQVE YAMEAIGHAGTCLGILANDGVLLAAEKRNVNKLLDEVSYSEKIYKLNEDMACSVAGITSD ANVLTNELRMIAQRYLLTYQDPVPCEQLVATLCDIKQAYTQFGGKRPFGVSLLYMGWDKH HGYQLYQSDPSGNYGGWKATCIGNNSQAAVSMLKQEYKEGEIKLSAALALAIKVLGKTLD TNKLTSEKIEIATLTRVDGQTVIRIVPANELDAQIKIHEEEEAKAEAEKKK--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------LRKHFTQAANVFH QWLTETRACMMEGTGSLEQQLEATKHKSTEVRAQKSQLKKIEDLGAAMEERLILDNRYTE HSTVGLAQQWDQLDQLGMRMQHNLEQQIQACNQSGVSEDALREFSMMFKHFDKDKSGKLD HHEFKSCLRALGYDLPMVEEGERDPEFETILDIVDPNRDGHVSLQEYMAFMISRETENVQ SSQDV------------------------------------------------------- --------SIQCYQCDSNEDKSCPTWLWFDTNYNAMVDCNSFEAKVPGTFCMKITQQSPG WGSWKKVTRRCGSRSDTGVAWGCRWTFEDNGIWKEVCYCEDKDGCN----IDKDDKDNPQ LVAEYVNDIYDYMRELEMREINGRMRGILVDWLVQVHLRFHLLQETLYLTEAIIDRFLQE TVTRSKLQLVGVTCMLIASKYEEMYAPEI----------------------ILETLGFNL GRPLPLHFLRRNSKAGEVDATTHTLAKYLMELTIVEYDMVHIHPSKIAAGALCLAMQILD WSETLCHYSKYTEEEMKPVIQKMASLVLKKLTAIFTKYQSSKFMRISTYPQLKSQLVQDI AXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------- ------------------------------------------------------------ ---------------------------------------KCKIHPTSIISGYRLACKEAC KYIQEHMCINTDELGRECTINCAKTAMSSKVIGPLSDFFSTMAVDAAMAIKT-----GNK YPIKAINVLKAHGGSMKESQLVHGYALNCTVASQAMTKKITGAKIALLDFSLQKAKMKLG VQVLVEDPTKLDAIRQRESDITKERIQKILATGANVVLTTGGIDDLCLKYFVEAGAMAVR RCKKIDLKRIAKATGGQLVVSMANLEGEEVFEASMLGQAEEVVQDRICDDELLLIKGTKA RSAASI----------------------------ESKQVVPGGGAVEAALSIYLENFATS LSSREQLAIAEFANALLCIPRQLSVNAAQDSTDLVAKLRAFHNTSQTKPEHASLKWVGLD LIEGKVRDNKEAGVFEPAMSKVKSLKFATEAAITILRIDDLIKLTPEQKEGSAYQQALRS GQL---------------------KDLTVEYAIYNIGTSSAVDVELTDTTFPDSDFQVTN GYLNVKWARIAPSSNVSHVVILQPQRSGYFNFTSAEISYLPSEEERKLGYTSAPGEGPIM NQKDYDRKFSPHVLDWAAFTLMT--PLGIPFLLWHKSKSKYDQPKSVKK----------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------IPPAK AEKIASQMITEGRMNGCIDQLDSIVHFESREALPSWDKQIQSLLLQLNNIIEKVSVHSPE WMTRTLDAQMTMKLTDTVVRSFRVSKLFRENTERINNVDFSTNGETLISSSEDDSIVIYD CQNGTPKRTLNSKKYGVDLIHYTHAQNTAIHSSTKVDDTIRYLSLHDNKYIRYFPGHTKK VVTLCMSPIDDTFLSGSLDKTIRLWDLRSPNCQGLMHVPGRPVAAFDPEGLIFAAGINSE SIKLYDLRSFDKG----------------------------------------------- ------------------------------------------------------------ ------------------------EYVIVDRCGKNNNVGLIQLNRPKALNALCDGLMLEL NSVLDEIENDPEIGCVILTGSEKAFAAGADIKEMQPVAFKHAYTVNFLDHWSRVAGFKKP IIAAVNGFALGGGCELAMMCDIIYAGEKANFGQPEITIGTIPGAGGTQRLTQTIGKSKTM ELVLTGTPFTAQEAEKAGLVSKIFPPDQLLEEAIKTADKIASKSKIITMMAKEAVNASFE VPLREGLKFEKRLFHQTFATHDRKEGMQAFIEKRKPDFKD >Platynereis_dumerilii XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXM SHYKEAGKAPEAPIHRIRITLTSKNVKSLEKVCADLIRGAKDKNLKVKGPVRMPTKILRI TTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXRKGKVQKVQLGPVVVEGENVFGVAHIFASFNDTFVHVTDLSGKETICRVT GGMKVKADRDEASPYAAMLAAQDVAERCRTLGITALHIKLRATGGNKTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPTDCTRRKGGRRGRRLMGKPRGLRTARKLKNHRRDQRWHDKD YKKSHLGTRWKANPFAGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP RDGCLNYIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLWALYKEKKERPRSEGL VTLRTRKFLTNRLLCRKQMVVDVLHPGRATVAKTEIREKLARMYKTTPDVIFAFGFRTQF GGGKTTGFALIYDSLDFAKKFEPKYRLCRHGTRKQRKERKNRQKKVRGTAKSKIGAMPRI PLVYSKTYTTPRRPFEKERLDQELKLIGEYGLRNKREVWRVKYTLAKIRKAARELLTLDE KEPRRLFEGNALLRRLVRIGVLDEGKMKLDYVLGLRLEDFLERRLQTQVFKLGLAKSIHH ARVLIRQRHIRVRKQVVNIPSYVVRLDSQKHIDFSLRSSYGGGRPGRVKRKNMRKGTGGG GDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXX--RMNVLADALRSLINAEKRGKRQVLIRPCSKV IVRFLTVMMKHGYIGEFEIIDDHRSGKIVVNLTGRLNKCGVISPRFDIALRDMEKLTTNL LPSRQFGFLVLTTSGGIMDH-XARRKHLGGKILGFFF-GGMLAPGKGISQSALPYRRTVP TWLKLTSDDVKEQIFKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKSKGLAPD IPEDLYHLIKKAVAIRKHMERNRKDRDSKFRLILVESRIHRLARYYKSRRVLPPNWKYES STASALVA--EVPEIKLFGKWSSEDVQVSDISLTDYVAVKEKFAKFLPHSGGRYQVKRFR KALCPIVERLTCSLMMHGRNNGKKLMAGRIVKHAFEIIHLLTGENPLQIVVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGARESAFRNIKTIAECLADELINAAK GSSNSYAIKKKDELERVAKSNRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMREYKLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKVVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKLARNFNCAFLETSAKSK INVNEIFYDLVRQINKKNPETXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMDDFQTGEETAFVVDEVS NIIKESIEGAIGGNAYQLNKVNQWTSNVVEQCLNQLTKLGKPFKYIVTCVIMQKNGAGLH TASSCFWDNTTDGSCTVRWENKTMFCIVSVFGLAI--SASAKIVKPQGEKVDEFESSISQ ALLELEMNSDMKAQLRELFITGAKEIDVQGKKAIIIFVPVPQLRAFQKIQIRLVRELEKK FSGKHVVLIAQRRILPKPTRKTKRKSKQKRPRSRTLTAVHDNILEDLVFPAELVGKRIRV KLDGSRLIKVHLDKTQQTTVEHKLDTYSAVYKKLTGKDVNFEFPEYVLXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXMKFNKMVSSARRKNRKRHFNAPSHVRRKIMSSPLSKDLRQKHNVRSMPIRKDD EVQVVRGHYHSQQVGKVVQVYRKKFVIHIERIQRDKANGASVNVGIHPSKVVIVKLKMDR DRKRILERKAKSRQSGKHTEESIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNPEKLKQRIGGKGTARRKKKVVHRTATTD DKKLQSSLKKLAVNNIPGIEEVNMIKDDGHVIHFNNPKVQASIAANTFAISGHAEMKQIT EMLPGILNQLGAESLQSLKKLATATDDID-EDDEVPDLVENFDEASKDEXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXMGISRDKWHKRRKTGGRQNPLRKKRKFELGRPAANTKIGP KRVHTVRTRGGNTKYRALRLDTGNFSWGSEAQTRRTRIIDVLYNASNNELVRTKTLVKNA IIQVDATPFRQWYESHYTLPLGRKKGVKLSEAEEAVLNKRSKKIQKKYNDRKKLAKVEQV LEEQFATGRLLACLSSRPGQTGRADGYVLEGKELEFYLKKIRARKGKXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXX----DDDSDDDAADNEEVAQAAGIPEELVSKAKQSRSEKKA RKAMGKLGLKQVGGVSRVTIRKSKNILFVINRPDVYKSPASDTYIVFGEAKIEDLSQQAQ VRAVDQFKADEEIDDTGVEAKDIELVMSQANVSRAKAVKALKNNSNDIVNAIMXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGIKFLEFVKPFCAVLPEIAKP ERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGIS PIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMVITIGQAIVYVMTGMYGNPAD IGAGVCLLIIIQLFVAGMIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVN TGRGTEFEGAIIALFHLLATRADKVRGLREAFYRQNLPNLMNLLATIFVFAVVIYFQGFR VDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAAKFSGNFFINLLG VWADVGGGGPARSYPIGGLCYYLSPPETLGHVVEDPVHAVLYIIFMLGSCAFFSKTWIEV SGSSAKDVAKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIG SGTGILLAVTIIYQYFEIFVKEQSEMGGMSTLLFQSERAFQKQPTVFLNRKKSA-LRYVK SIGLGFKTPREAFDGTYIDKKCPFTGNVHIRGRILSGVVLKMKMQRTIVIRRDYLHYVRK YNRFEKRHKNMSVHLSPCFRDVKIGDVATVGECRPLSKTVRYNTIKITKGAGSKKGFSKF XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRVIRAQRKGAGS VFKCHSKHRKGAARLRAVDFAERHGYIKGVVRDIIHDPGRGAPLAKVAFRDPYRYKLKTE TFVASEGMYTGQFLYCGKKATLQIGNILPVGQMPEGTVICCMEEKSGDRGRIARASGNYA TVVSHNPDAKKSRVKLPSGAKKVIPSTNRAMVGIVAGGGRIDKPMLKAGRAYYKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGKASTVRRDASAGKKVGLIAARRTGRLRGSK---- -XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGAYKYMQEMYRKKQSDVLS FLLRVRCWQYRQLTAIHRAPRPTRPDKARRMGYRAKQGYVIYRCRVVRGGRKRPVPKGAT YGKPTNQGVNQLKNQRSHQAIAEERIGRRLRQMRILNSYWVGQDSTYKFYEVICVDPHHK AVRRDAKINWICNPVHKHREMRGLTSANKKSRGLGKGHKFTQTIGGSRRAAWKRNTYLQL RRKRGIAIGRLTEERKAWRKDHPFGFVARPIKNPDGTLNLMNWECAIPGKKTTPWEGGLY KLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSLLDEEKDWRPAVTIKQILLGIQE LLNEPNIKDPAQAEAYTIYCQNKVEYERRVREQARRFLDPS-XXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXQNVPTFKLVLVGDGGVGKTTFVKRHLTGEFEKKYVATLGVEVHPLSFHTNRGVIRF NVWDTAGQEKFGGLRDGYYIQGQCAIIMFDVTSRITYKNVPNWHRDLVRVCENIPIVLCG NKVDIKDRKVKAKAIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLVGDPNLEFVAMPA LAPPEVSMDPSLVRQYEQELELAQQTALPEEDDDLTEGIKGYYISKIEELQLVVTEKTQN LRRLEAQRNELNAKVRMLREELQLLQEQGSYVGEVVKPMDKKKVLVKVHPEGKFVVDIDK NIDMNDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEI KEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ KFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRLEAGSGGDSEVQRTMLELLNQLD GFEPKQNIKVIMATNRIDILDSALLRPGRIDRKIEFPAPNEEARLDILKIHSRKMNLTRG INLRKIAEMMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFELAVAKVMQKDSEKNMSM KKLWKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXMARGPKKHLKRLHAPKHWMLDKLGGNFGPRPSSGPHKLRECLPLMVFLRN RLKYALTYDECKKILNQRLVKIDGKVRTDNTYPAGFMDVVTIEKTAENFRLIYDVKGRFT VHRITPEEAKYKLCKVRAVRTGPKGVPMLSTHDGRTIRYPDPLVKVNDTVRVMGTKDDEY DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTA GQERYRAITSAYYRGAVGALLVYDIAKHLTYENVDRWLKELRDHADNNIVIMLVGNKSDL RHLRAVPTEEAKAFAEKNNLSFIETSALDSTNVEAAFQNILTEIYNIVSQKQIRDSPDD- ----------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXSGGQGGDKKDDKDKKKKYEPPVPTRVGKKRRKT KGPDTANKLPLITPHTRCRLKLLKLERVKDYLLMEEEFIKNQERLKPQEEKQEEERSKVD DLRGTPMSVGSLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDQLEPGCSVLLNHKVHAVV GVLGDDTDPMVTVMKLDKAPQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIKPPK GVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHSPS IVFIDEIDAVGTKRYESNSGGER------------------------------------- ------------------------------------------------------------ ----------------------------------------XXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMKLNISYPATGCQKLLEVDDERKLRAFYDKRISAEVGADSLGDEWKGYVVRIGGGND KQGFPMKQGVLTTSRVRLLLSKGHSCYRPRRTGERHRRSVRGCIVDGNLSVLSLIIIRKG EQEIPGLTDTTVPRRLGPKRASKIRKLFNLGKDDDVRQYVVRRPLPPRTKAPKIQRLVTP VVLQRKRHQMALKKKRAAKKREDMADYTKLLAARMKEAKERKAERRRSASQSKQVKTKEL RGKKKEELEKQVLELKNELSSLRVAKVTGGAASKLSKIRTVRKSIARVLTIINQTQKDNL RKFYKPKDLRQKKTRAMRRALTPFEKNIKTRKEQRRLTLYAKRKFAVKXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-KKKSVLKFTVD CTHPVEDGIMDCSNFEKFLQERIKVNGKTNNLKSKVEVNSDIPFSKRYLKYLTKKYLKKH NLRDWLRVVAANKEAYELRYFQINNEDDEEEDNENKEEKGEEDKVYGGCEGPDAMYVKLV SSDGHEFIVKREHALTSGTIKAMLSGPGQFAENETNEINFREIPSHVLQKVCMYFTYKVR YTNSSTEIPEFPISPEIALELLMAANFLDCXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX-RRVQAMAEDLRNVEFETSEEVEVTPTFDDMGLREDLLRGIYAYG FEKPSAIQQRAVKPILKARDVIAQAQSGTGKTATFSISILQSLDTQIRETQALVLSPTRE LATQIQKVILALGDYMSVQCHACIGGTNVGEDIRKLDYGQHVVSGTPGRVFDMIRRRNLR TRSIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVLLISATLPHEILEMTSKFMTDPI RILVKRDELTLEGIKQFFVAVEKEEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKM REANFTVSSMHGDMPQ-------------------------------------------- -------------------------------------------------------AVRRP FDPVAHELDANFRLTRFADLKGGCKVPQEVLLKLLEGL-QAQESEQAHFQYVAACPRIGI GMDSCVTPLRHGGLSLVQTTDFFYPLVDDPYMMGKIACANVVSDLYAMGVTECDNMLMLL GIPQKMAEKERDVVVPLMMRGFKDAADEAGTSVNGGQTVLNPWFTIGGVATTVCLPNEFI MPDNAVVGDVLVLTKPLGTQVAVNAYQWLEQTDRWNRIKLVVSEDDVRKAYQRAMFSMAR LNRTAARLMHKYNAHGATDVTGFGLLGHANXLARIQKNEVGFVIHNLPVIAKMAAVSKAC GNLFGLLQGNSAETSGGLLIALPREQAAAFCKDIEKQEGYQ------------------- ------------FILSVIGNVEGYFINIDAHAEECFFDKVQSGTKMSLMFEVAEGGFLDI DVSIVGPDGKNIYSGERETNGKYTFAAHMDGIYKYCFSNKMSTMTPKIVMFSMDIGEKPK AQHNKLEEMITELSTSLTGVKHEQEYMEVRERIHRAINDNTNSHVVVWSIFEALVLVAMT LGQIYYLKRFFEVRRVVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSYAYLF KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES FRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSNSNMVIMLIGNKSDLEARR DVKKEEGEAFAREHGLIFMETSAKTAANVEEAFINTAKEIYQKIQDGVFDINNEANGIKI GPQHSPSNPSGGGGAKQGGSLMRGRTELGDVTVHNIKQLKRLNQVVFPVTYNDKFYKDVL EVGELAKLAYFNDIVVGAVCCREDKSDEQRRLYIMTLGCLAPYRRLGIGTVMLHHVLKVC EQDGNFDNVFLHVQVNNEGAIKFYEKFGFEIVEQKQNYYKRIEPADAYVLQKTFR-XXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX---LSRELLNDSLANVLKKKRKFQETVELQIVLKNYDPQKDKRFSGTVKLRHIPRPK MSVCVLGDQQHCDEAKANNVACMDVDALKKLNKNKKLVKKLSKSYDAFLASDSLIKQIPR ILGPGLNKAGKFPTLLTHSDSMLGKVDEVKATIKFQMKKVLCLAVAVGHVNMSHEDLYGN ITLSINFLVSLLKKNWQNIRALYIKSSMGPAQRIYXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXTARVAQGLARQVPRALRQKNSLGAGFVSTRNITTSAEVSSILEERILGSTTANLEET GRVLSIGDGIARVYGLKNIQAEEMVEFSSGLKGMALNLEPDNVGIVVFGNDKLIKEGDIV KRTGAIVDVPVGDGILGRVVDALGNPIDGKGPLDAAKRARVGVKAPGIIPRISVREPMQT GIKAVDSLVPIGRGQRELIIGDRQTGKTAVAIDTIINQQRFNSGTNEKAKLYCIYVAIGQ KRSTVAQIVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCAMGEFFRDTGKHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNETNGGGSLTALPVIE TQAGDVSAYL-------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEYAQVTKMLGNG RLEAMCIDGTKRLCHIRGKLRKKVWINSSDIILVGLRDYQDAKADVILKYNAEEARNLKA YGELPETININDDMDDNVTFEDIDDIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLMAK PKSEMTPEELAQREQEEFNTGPLSVLTQSVKNNTQVLINCRNNKKLLGRVKAFDRHCNMV LENVKEMWTEVPRTGKGKKKSKPVNKDRYISKMFLRGDSVILVLRNPLXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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RLVAMKFVQADEEHLKKHYADLAGRPFFAGLVKYMSSGPLVPMVWEGGVVKTGRVMLGET DPAKSLPGTIRGDYAVEVGRNICHGSDAVESAEKEIALWFKPEELQAWKPVSQPWIVEXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX X----------------------------------------------------------- ------------------------------------------------------------ ---------------------------LKNRRYQIFMTSAIKGEGLDEGMEWLANALSNQ KXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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KAWVDIEKVKNSRRFRAGKGKMRNRRRIQRRGPLIIYNQDSGITRAFRNIPGITLLSVDR LNLLKVAPGGHVGRFCIWTESAFGQLDNIYGTWRKKSATKNNYNLPMNKMTNNDLARLFK SDEIQKVIRAPNKTRFRHVLKKNPFKNTRIMTRLNPFAPVQKKNAIQKQARQRFRDSRRG IAVFEVPGKARPRQTIAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSHRKFSAPRHGSLGFLPKKRARRHRGKV KAFPKDDQNKPCHLTAFLGYKAGMTHVVREVDRPGSKTNKKEIVEAVTIVETPPMIIVGV 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KPGDLVGVNKDSYLVLETLPAEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELIEAVVLP MTHKERFEALGIQPPKGVLLYGPPGTGKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGA KLVRDAFALAREKTPAIIFIDELDAIGTKRFDSEKAGDREV------------------- ------------------------------------------------------------ ------------------------------------------------------XXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --EIDVINSRTQGFLALFSGDTGEIKGEVREQINAKVAEWREEGKAEIVPGVLFIDEVHM LDIECFSFLNRALESDMAPILIMATNRGITRIRGTNYESPHGMPIDLLDRLLIISTSPYE EKDIKQILKIRCEEEDVEISDDALTVLTRIGQETSLRYAIQLITTANLVCRKRKGTEVGV DDIKRVYSLFLDESRSTQFLKEYQQEFMFNE-AEFDLTSRMGCYLDRHLVFPLLEFLSVK KIYDESEMLEGKLNLLSNTNMVDFAMDVHRSLHPDADVPLSLRERRSEVVSQLKQLQVET EAITKIFDDPEVMIQTARDGRQLFNDLSKNYGFKPEMVDKLYAYAKFQYECGTYSGAAEY LYFARVLLPPNDKNYIPALWGKLASEILMQDWDTALEDLNRLKDIVDNPLQSLQQRTWLI HWSLFVFFNHPKGRDLIIDMFLYQPQYLNAIQTMCPHILRYLTTAVITNKTVLKDLVKVI QQESYTYRDPITEFLECLYVNFDFDGAQQKLRECETVLLNDFFLVACLDDFIDNARLFIF ETFCRIHQCLSINMLAEKLNMTPDDAERWIVNLIRNARLDAKIDSKLGHVVMGAQAISPY QQVIEKTKGLAFKTQMLIMNIEKKLGPKQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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LRKELMEKVVRVVIPDKYLDDKTVFHIQPSGRFVIGGPQSDAGLTGRKIIVDTYGGWGAH GGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVSEPLSIFVTSYGT GVRPDNELLRIVKENFDLRPGRIVKD--------------------------------XX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------------------- ------------------------------------------------------------ --------------KRFTVYVTEKAGATMIRDLERADITCVSVLDAAVGYIMEKVDMVLV GAEGVVESGGIINKGAYTMALAVKEMNKPFYIVAESFKFA-------------------- -------------------------------------XXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKARGQLKEYKVIGRMVPTEKNRV PPLYQLRIFAPDPITARSRFWYFCAMLRKMKKTQGEVVLCQQVHERRPSVIKNFGIWLRY DSRSGTHNMYREYRDLTTASAVTQCYRDMGARHRARACNIQIMRVEVIPAAKCRRANIKQ FHDSKIKFPLPHRISKRLHTPRFTTKRPHTYFXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXKPNYTLKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGH KGGISDVAWSTDSRLLVSAADDKTAKIWDVATGKCLKTLKGHSGYVFCCNFNPQSNLVVS GSFDESVRTGRCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHVNAKYCIFANFS---- ------------------------------------------------------------ ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------- ------------------------------------------------------------ ------------------------------------------------------------ -YETKVHRKTLNPVFNETFVFKVPYAEIGSKTLVFAIYDFDRFSKHDQIGQVQVPLNSVD LGRVVEEWRDLSSPENDSE---KLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSD PYVKLSLMLNGKRIKKKKTTIKKCTLNPYYNESFTFEVPFEQIQKVTLIITVVDYDRIGT SEPIGRVVLGCNATGTELRHWSDMLANPRRPIAQWHTLQEMPEKNMVLADLGRKITSALR SLGSATVINEEVLNSMLKEICAALLEADVNIKLVKKLRENVRSVIDFDEMAAGLNKRRMI QSAVFQELVKLIDPGVKAWTPTKGRNNIIMFVGLQGSGKTTTCTKLAYYYHRKGWKTCLV CADTFRAGAFDQIKQNATKARIPYYG---------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMTSKDYYFDSYAHFGIHEEMLKDEVR TTTYRNAFYHNRHLLKGKVVLDVGCGTGILCMFAAKAGAKKVIGIECSSIVEHAEKIVKA NKLDHIITLVKGKVEEVSLPDGIEKVDIIVSEWMGYCLFYESMLNTVILARDKWLAPGGF IFPDRATLYICAIEDRQYKDEKINWWDSVYGFDMSCIRKVAISEPLVDIVDPKQVVTNSC LVKEVDIYTVTEDDLTFNAPFHLQCQRDDYAHALVTFFNIEFTKCHKRTGFSTAPESRYT HWKQTDDYLTVKAGEELCGQINIKPNKRNQRDLDFSIEVEFKGELSSMSENNNYKMRMVK EDRGTWKSNYFIKLINLLDEYPKCFIVGVDNVGSKQMQQIRIALRVLMGKNTMIRKAIRG HLDNNPALEKLMPHIRGNVGFVFTKLDLSEVREIIMANKVAAPAKTGAIAPCDVSIPAQN TGLGPEKTSFFQALAIPTKIARGTIEILNEVKLLRTGDKVGMSEATLLNMLNVSPFTYGL VILQVYDSGTVFSPAILDITDDDLRARFMQGVTNLSCVALAIGYPTVASVPHLVINGFKN LLAIAAETDIEFKEAEQMKE-------LAVIGDEDTCTGFLLGGIGELNKHRQPNFLVVD KNTSVSELEEAFKNFSNRDDISIILINQNIAEVIRHVIDAYDQPIPAVLEIPSKDHPYDA SKDSVLRRAKGVISAEDMKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSE YMFNIDNGYLEGLLRGFKGGILKQADYLNLVQCETLEDLKLHLQSTDYGNFLANEASPLS VSVIDDKLKEKLVIEFQHLRNHSVEPLSTFLDYITYSYMIDNIILLITGTLHQRAISELI PKCHPLGSFEQMEAIHIASTPAELYNAVLVDTPLAAYFIDCISEQDLDEMNIEIIRNTLY KAYLEDFYRFCENLGGATANVMCEALAFEADRRAFIITINSFGTELTKDDRSKLYPRCGK LHPDGLAALARADDYEQVKAVAEY------------------------------------ ---------------------------------------------SPRKAVRKISKIPFK VLDAPELQDDFYLNLVDWSSQNVLSVGLGTCVYLWSACTSQVTRLCDLSCESDSVTSVSW SERGNSIAVGTHK----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------KAPRIRTKNLVSIIFCEAVAIYGIIMAIVISNSMNALAGY SMFGAGLTVGFSNLFCGVCVGVVGSGAALADAQNSSLFVKILIVEIFGSAIGLFGVIVGI 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------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------KPLLKTVMRKWLPAGEALLQMIAIHLP SPVTAQKYRMELLYEGPQDDEAAVAVKACDAKGPLMMYISKMVPTTDKGRFYAFGRVFAG CVQTGHKVRIMGPNYTPLKSIQRTILMMGRYVEPIEDVPCGNICGLVGVDQFLVKTGTIS TFEHAHNMKVMKFSVSPVVRVAVECKNPSDLPKLVEGLKRLAKSDPMVQCIIEESGEHII AGAGELHLEICLKDLEEDHAGIPLKKSDPVVSYRETVSEESDRTCLSKSPNKHNRLFMRA RPMPDELANDIEDGKVTPRQELKERARYLADTYEFDVTEARKIWCFGPDGTGANLVIDCT KGVQYLNEIKDSVVAGFQWATKEGVLCEENMRGVRFDIHDVTLHADAIHRGGGQIIPTTR RVLYACCLTASPRLLEPVYLVEIQCPEQAVGGIYGVLNRKRGHVFEEFQVAGTPMFMVKA YLPVNESFGFTGDLRSNTQGQAFPQCVFDHWQILIVADIRKRKGLKEGIPALDNYLDKLX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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SNRAIQKLRREVEKAKRALSAQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMK PVQKVMEDADLAKTDIDEIVLVGGSTRIPKIQQLVKEYFNGKEPSRGINPDEAVAYGAAV QAGVLSGEEDTGDLVLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQIFSTASDNQPT VTIQVFEGERPMTKDNHLLGKFDLTGIPPAPRGVPQIEVAFEIDANGILKVSAEDKGTGN KEKIVINNDQNRLSPEDIERMINDAEKFADDDKKVKEKVESRNELESYAYSLKNQIGDKE KLGAKLSDEDKTTIEKAVDEAIAYLDANQEAESDEYKAAKKKLEDIVQPIMTKLYQG--- EGGEEDHDELXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------------------- ------------------------------------------------------------ -----------KYEKRVHILPIDDTIEGITGNLFEVYLKPYFLEAYRPVRKGDIFLVRGG MRGVEFKVIETDPSPYCIVAPDTIIHCEGEPVKREEEEEALNEVGYDDIGGCRKQLAQIK EMVELPLRHPQLFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSK LAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEVERRIVFQLLTLMDGLKQ RAHVIVMAATNRPNSIDAALRRFGRFDREVDIGIPDATGRLEILRIHTKNMKLADDVDLE QVAAETHGHVGADLAALCSEAALQQIREKMDLIDLEDENIDAEVLDSLAVSQENFRWALS KSNPSALRETSVEVPTVTWEDVGGLENVKKELQELVQYPVEHPDKFLKFGMTPSKGVLFY GPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFD ELDSIAKARGGNVGDGGGAADRVINQLLTEMDGMGAKKNVFIIGATNRPDIIDPAILRPG RLDQLIYIPL-------------------------------------------------- ------------------------------------------------------------ --------GGTSVFGAQQ------NTAAKQNIEVTSPPDDSVSSLEFSPSTLPSTYLVAG SWDNNVRCWEIQQSGQTIPKAQQTHAGPVLDVAWSDDGTKVFTASCDKTAKMWDLNSNQA LQVAQHDAPIKTVHWIKAPSYSCLMTGSWDKTLKFWDTRTPNPMLTIQLPERAYCADVLY PMAVVGTANQGLVIYQLENQPQEFKKIDSPLKYQHRCVSIFTDKKSNAPTGFALGSIEGR VAIHYVNPQNPKDNFTFKC----------------------------------------- ------------------------------------------------------------ ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXVIWSIINKTFCSFKTRTKSQKFCRNEYNLTGLCNRSSCPLANSQYATVREEKGVIYL YMKTIERAAFPRRLWEKVKLSRNFEKALSQIDEHLIYWPKYFINKCKQRHLRITQYLIRM RRLSLKRQKKLVPINKKVERREKRREEKALIAAQLDNAIEKELLDRLKKGTYGDIYNFPQ MAFDKALEKEEIEEEEEDESEMEEDSDAEI---------XXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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IHDALCVIRCLVKKRALIAGGGAPEIELSLRLSEYSTTLTGMEQYCFRAFAEALEIIPFT LAENAGLNPISTVTELRNRHAQGEK----------------------------------- ---------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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VMAEFV-GGGWVHSVSFSSDGNKLAWVGHDSSVDVANA---------------------- ------------------------------------------------------------ -----------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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VVTLDMSPVDDTFLSGSLDQTIRLWDLRSPNCQGVMNLPGRPAAAFDPEGLIFAAGINSE CIKLYDLRSFDKGPFSTFKLQQEKECQWTSLKFSPDGKLILLATNGNVLRLIDAFQGAPV QTFMGHTN-RGLALEACFSPDSQFVFSGSCDGKVHVWQTETGLRAGVMNSDHPGPIQCIR FNPKY------------------------------------------------------- ------------------------FAAGADIKEMQPKDFQSVYKENFLAHWDAVARSRIP IIAAVNGYALGGGCELAMMCDIIYAGDRAKFGQPEILLGTIPGAGGSQRLTKAVGKSLTM EMVLTGDQISATEALSAGLVSKIFPAAELVDQAVKTAEKIAAQSPIIVQMAKDAVNASFN STLDEGLRIEKRFFYASFATEDRREGMTAFVEKRPADFKN >Pomatoceros_lamarckii MSERKAVIKNADMAEDMQQDAVDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSGLSTQIRQFQTSVARRDIDQAAKYIGAGAATV GVAGSGAGIGSIFGSLMIGVSRNPSLKGQLFSYAILGFALSEAMGLFCLMMAFMMLFAL- ------GKAPEAPIHRIRITLTSRNVKSLEKVCADLIRGAKDKQLKVKGPVRMPTKTLRI TTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADMDQVM QVVEPAKTFAKDSLRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGYFVKLIHIPINNII V-----SKKRKFVADGVFQAELNEFFTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVL GEKGRRIRELTSVVQKRFNFPEGTVELYAEKVATRGLCAIAQAESLRYKLIGSLPVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPCNDYIDTAVRHVLLRQ GVLGIKVKIMLPWDPTGKLGPKKPLPDHVSIVEPKEEQAIVAPYSE-----------GGS AGGKFRISIALPVGAVINCADNTGAKNLYIIAVGGIKGRLNRLPAAASGDMVIATVKKGK PELRKKVMPAVVVRQRKAIRRKDGVFIYFEDNAGVIVNNKGEMKGSAVTGPVAKECADLW PRIASNASSIPLGKAPKVSLGPQVIEGENVFGVAHIFASFNDTFVHITDLSGKETLVRVT GGMKVKADRDEASPYAAMLAAQDVAERCKALGITALHIKLRATGGNRTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRLMGKPRGLRTARKLRTHRRNQRWHDKD YKKSHLGTRWKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP RDGCLNYIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKEKKERPRSESV ATIRTRKFMTNRLMCRKQMVVDVLHPGRSTVPKTEIREKLARMYKTTPDVVFVFGFQTKF GGGKTTGFGLVYDSLDYAKKLEPKYRLARHGARKQRKERKNRQKKVRGTKKAKVGA--RV PLVCSKTYTTPRRPFEKERLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLEE KDPKRLFEGNALLRRLVRIGVLDESKMKLDYVLGLRVEDFLERRLQTQVFKLGLAKSIHH ARVQIRQRHIRVRKQVVNIPSYIVRLDSQKHIDFSLKSPLGGGRPGRVKRKNMKKGKGGG ADMGAVFGTLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERITEAREELMRMLSEDELRE AVLLVFRNKTDLPKCMNAAEITDKLNLHNLRNRNWYIQATCATSGDGLYEGLDWLSAQLK N--MPLAKDLLHPSPEEERRKCKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVVCA GCATVLCQPTGGKARLTEGCSFRKK--MVRMNVLADALKSICNAEKRAKRQVLIRPSSKV IVRFLTVMMKHGYIGEFEIIDDHRSGKIVVNLTGRMNKCGVISPRFDVGVSDIEKWTNNL LPSRQFGFIVLTTSGGIMDHEEARRKHLGGKILGFFFMGRMHAPGKGISQSALPYRRSVP SWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGSKVLRVLKAKGMAPE IPEDLYHLIKRAVSIRKHLERNRKDKDSKFRLILVESRIHRLARYYKTRKVLPPTWKYES STASAMVSVAELPEIKLFGKWSSEDVQVSDISLADYIAIKEKFAKYLPHSSGRYQVKRFR KAQCPIVERLTSSLMMHGRNNGKKLMAVRIVKHAFEIIHLLTGENPLQVLVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREASFRNIKTIAECLADELINAAK GSSNSHAIKKKDELERVAKSNRMTEQMLLRGTLQGHDGWVTQIATTPQFPDMILSASRDK TLIQWSLTRDTSYGVPKKRLRGHGHFVSDVVMSSDGQFALSGSWDHTLRLWDLTTGETTR RFVGHTKDVLSVAFSADNRQIVSGSRDKTVKLWNTLGVCKYTIEDGHSEWASCVRFSPNT QNPIIVSCGWDKLVKVWNLTNCKLKTNHFGHTGYLNCVTVSPDGSLCASGGKDGQAMLWD XNERQHLYTLEGVTSXHALTFSPNRYWLCAATGPSIKIWDLEGKIVVDELKPEVMTT-AD PPQCISIAWSADGQTLFAGYTDSIIRVWQVSMAA-MREYKLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKVVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKLARQWNCAFLETSAKSK VNVNEIFYDLVRQINRKNPGPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXMSDAEGDDVPAAPATGGPMDINTALQEVLKTALINDGLARGLHEC AKALDKRQAHVCILANNCDEAMYVKLVEALCSEHGINLIKVDDNKKLGEWAGLCKIDKEG KARKVVGCSCVVVKDWGKETQAKDVLEDYFKNRK---VRRKLVVVGDGECGKTCLLIVFS QDEFPEVYVPTVFETYVADIQLGDTQVELALWDTAGQEDYDRLRPLSYPDTDVILLCFSL ENPDSYDNITEKWIPEVKHYCPNVPIVLVGTKKDLRHNKVIHDERTKRKYKHVQPEDGQM LADRIKAFSYIECSAKTRDGVREVFDTATKAAL---------MDDFQSSEETAFVVDEVS NIIKESIEGAIGGNAYQHNKVNQWTSNVVEQCLNQLTKLNKPFKYIVTCVIMQKNGAGLH TASSCFWDNSTDGSCTVRWENKTMYCIVSVFGLAIMFSANAKIVKPQGEKPDDFEASISQ AFLDLEMNSDLKQQLRELYITGAKEIDVHGKKAIIIFVPVPQLRAYQKIQARLVRELEKK FSGKHVVFIAQRRILPKPTRKSRIKNKQKRPVSRTLTAVHDAMLEDLVHPSEIVGKRIRI KLDGSRLFKVHLDKSSMTTVEHKLDTFTAVYKKLTGKDVTFEFPEQLVERGGFRGGFGGR GRGRGRGRGRGKEGDKEWIPVTKLGRLVKDMKIKSLEEIYLFSLPIKESEIIDFFIGPQL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDYDGHVGLGVKCSKEVATAIRGAIILAKLSI VPVRRGYWGNKIGKPHTVPCKITGKCGSVLVRLIPAPRGTGIVSAPVPKKLLQMSGIDDC YTSAKGQTATLGNFAKATYAAISKTYSYLTPDLWRETVFTKSPYQEHTDFLMKMSGGLDV LTLKEEDVQKFLACGTHLGSTNSDFQMMTYVFKRKQDGVHLINLRRTWEKLLLAARAIAA IENPADVCVISARPYGQRAVLKFASYTGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDP RTDHQPVREASYVNIPVIALTNTDSPLRHVDIAIPCNNKSSNSIGLMWWLLAREVLRLRG TISREVPWDVMVDLFFYRDPEEAEKEPEVTDWAADTVAPAVPIAKEDWSA--DTNWTQAA TTENWGGMKFNKMVSSSRRKNRKRHFQAPSHVRRVIMSSPLSKDLRTKYGVRSIPIRKDD EVQVVRGHYKGQQVGKIVQVYRKKFVVHIERIQREKANGATVHVGIHPSKVVIVKLKLDK DRKQILERKAKGKQLGKYQEET-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----KKTNVTSEVVTREYTIHMHKRIHGI GFKRRAPRAVKEIRKFAEKAMGTTDVRIDTRLNKHIWSQGVRNVPFRVRVRLARKRNEDE DSANKLYTLVTYVPVTSFKGLNTINVESXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNPEKLKQRIGGKGSARRKKKVVHRTATTD DKKLQASLKKLGVNSIPGIEEVNFIKDDGQVIHFNNPKVQASLGANTFAVTGHAETKQIT EMLPSILNQLGPESLTNLKKLATNPAEIDEDDDDVPDLVENFDEASKGEMVRYSLDPENA AKSAKARGSHLRVHFKNTHETARTIKHMHLRRAVAYLKNVVDKKEIVPFLKFNGGPGRHA QAKNMKASQGRWPKKSAEFLLSLLKNAESNAEFKGLDMDHLVIEHIQVNRAPKMRRRTYR AHGRINPFMSSPCHIEVILAEREQAIAKPVKKKVSQKKLKRQKMMQRE------------ ------------------------------------------------------------ -------------YDAEIKAAFDLFDKDKKGTIDAKXLREVLKEIKE---DESLAELDRD GDGEISFDEFKKAL------MGISQNRWHKRRKTGGRMPQIRSKRKFELGRPPAMTKIAP RRVHSVRTRGGNKKFRGLRLDHGNFAWGSEGQCRKTRIIDVLYNASNNELVRTKTLVKNA IVSIDATPFRQWYEAHYALPLGRKRGGKLTEEEEAQLNKRSKKTQKKYEDRQKTAKVEQH LEDQFATGKLMACISSRPGQCGKSDGYILEGKELEFYTRKIKSKKGK------EKFQHIL RVMNTNIDGRRKIPFALTAIKGIGRRYSHIVCKKADVDVNLRAGELSDEEVEKIITIMSN PRQYKIPDWFLNRQRDVKDGKTTQVMSNILDNKLREDLERLKKIRNHRGLRHYWGLRVRG QHTKTTGRRGRTVGVSKKKGSNTDSDSDDSAPDLEEIAQAAGLPEELTSKQKQSRSEKKA RKAITKLGLKPITGVTRVTIRKSKNILFVINRPDVYKSPASDTYIVFGEAKIEDLSQTAQ IQAAKRFEANEEVDEAGIEAKDIELVMSQANVSRNKAVKALKNNQNDIVNAIMMGRVRTK TVKKAARVIIEKYYPRLTLDFHTNKRIAEEIAIIPSKRLRNKIAGFVTHLMKRIQKGPVR GISIKLQEEERERRDNYVPEVSALEEVDPLTKEMLKMLDMANMQGLQVTQPMPAGMKWEY KEEHPFEKRRAEGEKIRKKYPDRVPVIVEKAPKARVGDLDKKKYLVPSDLTVGQFYFLIR KRIHLRAEDALFFFVNNVIPPTSATMGALYQEHHEEDFFLYIAYSDESVYGMRDLRIQKL CLNICVGESGDRLTRAAKVLESLTGQQPVFSKARYTVRSFGIRRNEKISVHCTVRGAKAE EILERGLKVREYELRKGNFSDTGNFGFGIQEHIDLGIKYDPSIGIYGMDFYVVLARPGFR VGYRRKRHSKIGFGHRVKKDESMKWFQRKYDGVILPGKXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQTERGFQKQGNVFLNKKKVAVPRYHK SIGLGFKTPREAIDGTYVDKKCPFTGNVTIRGRILTGVVQKMKMQRTITVRRDYLHYIRK YNRFEKRHKNISAHMSPCFRDVVPGDIVTLGECRGIAKTVTFNVIKVAKGSGGKKGFSKF --NVPKARKTFCKGQKCRKHTLHKVTQYKKGKDSLKAQGKRRYDRKQSGYGGQTKPVFHK KAKTTKKIVLKMECTVCKYKKQLPIKRCKHFELGGDKKKKGVMIQFMGRVIRCQRKGAGS VFRSHNKHRKGAAKLRAVDFAERHGYIKGVIKDIIHDPGRGAPLAKVAFRDPYRYKQNSE MFIAAEGMYTGQFVYCGKKANLQIGNILPVGTMPEGTIVCCLEEKTGDRGRIARTSGNYA TVISHNPDTRKTRVKLPSGSKKVIPSANRAIVGIVAGGGRIDKPMLKAGRAYHKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGHASTVRRDTSAGRKVGLIAARRTGRLRGSKQ--- -AKRTKKVGIVGKYGTRYGASLRKTIKRMEVTQHGKYTCSFCGKENMRRRCVGIWTCKSC KKTVAGGAYVYSTTNAATVRSAVRRLRENREMGRRPARCYRYCKNKPYPKSRFCRGVPDS KIRIYDLGRKKARVDDFPLCIHMVSDEYEQLSSEALEAARICANKYLVKNCGKDSFHMRI RCHPFHIVRINKMLSCAGADRLQTGMRGAFGKPQGTVARVNIGQIILSVRGRDSNKAHII EALRRAKFKFPGRQKIHVSSKWGFTKWEREDFEGMRSEGKLVPDGVSVQYRPDHGPLQRW MEAQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---ESGAAKDLDSWIEQLMECKQLAENQVK TLCEKAKEILAKESNVQDVKCPVTVCGDVHGQFHDLMELFKIGGRSPNTNYLFMGDYVDR GYYSVETVTLLVTLKVRFPHRITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDNQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDR--- ------------------------------------------------------------ ----------------------------------------MGAYKYIQELYRKKQSDVLR FLLRVRCWQYRQLASVHRAPRTTRPDKARRLGYRAKQGFVIYRVRVRRGGRKRPVPKGAT YGKPTNQGVNQLKFQRSLQSVAEERAGRKIQGLRVLNSYWVAQDSTYKYFEIIMIDPAHK AIRRDPKINWMCKSVMKHREMRGLTSAGKKSRGLGKGHTFTKTIGGSRHANWKKHNRFSA RRKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXEQIPTFKLVLVGDGGTGKTTFVKRHLTGEFEKKYIATLGVEVHPLVFCTNRGPIKF NVWDTAGQEKFGGLRDGYYIQGQCAIIMFDVTARITYKNVPNWHRDLVRVCENIPIVLCG NKVDIKDRKVKAKSITFHRKKNLQYYDISAKSNYNFEKPFLWLARKLVGDSNLEFVEMPA LAPPEIHLDSDLAAAY-------------------XXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXLTFAESFALSGAAAIISKTVAAPIERVKLLVQNQDEMLKTGRLDKPYKGVIDCTT RTFKNEGFLPFWRGNLANCIRYFPTQALNFAFKDQIKKAFKQKKTDPYMVNFGKNIASGG VAGAMSLCFVYSLDYARTRLANDAKSGKKRQFNGLIDVYKKTLKSDGVAGLYRGFVISCV GIVVYRGCYFGFYDTLKPIVLGDDSGLFLSFCLGYVVTVTSGLISYPIDTIRRRMMMTSG EAVKYKGSMDCGMQIVKSEGFMSLMKGAGANIFERSAGAGVLSGFDKFR--------XXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX VRLPPEVNRILYIKNLPYKITAEEMYDIFGKYGAIRQIRVGNTPETRGTAFVIYEDIFDA KNACDHLSGFNVCNRYLVVLYYQPNKAFKKTDLDKKAQELDNMKAKYGLSTPD--MSIGV PIKVLHEAEGHIVTLETTTGEVYRGKLIEAEDNMNCQMSTITVTYRDGRVNQLENVFIRG SKIRFLILPDMLKNAPMFKRVGAGRGKSAILSRAARGRGRGGGG-GRGGMQNDAGEYVDM YVPRKCSASNNIIAAKDHASIQINIAEVDDSTGRMTGSSKTYAICGKIRSMGESDDCLNR LAKKDSLI--MARGPRKHLKRLNAPKHWMLDKMGGCFAPRPSQGPHKLRESLPLIVFLRN RLKYALTGSEVKKIVNQRLIKVDGKPRTDTTYPAGFMDVVTIDKTGENFRLIYDVKGRYA VHRITPEEAKYKLCKVRTVGMASKGVPFVTTHDGRTIRYPDPLVKTNDSVKVMGTKDDEY DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDSKTIKAQIWDTA GQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDL RHLRAVPTDEAKAFAEKNNLSFIETSALDSTNVETAFHQILTEIYKIVSQKQIRDSPDD- ----------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----YSPFVGDNRADWALAR VDDLLNWSRKNSLWPLTFGLACCAVEMMHFAGARYDMDRFGVTFRASPRQADCIIVAGTL TNKMAPALRRIYDQMPHPRWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPS AEALLYSILQLQKKIKRLNKAQRWYRRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMVAQKKTKK AMESINSRLALVMKSGKYVLGYKQTLKTLRSGKAKLVIIANNTPPLRKSEIEYYAMLAKT GVHHYSGNNIELGTACGKFFRCTTLSITDPGDSDIIRTMPS-MTEYKLVVVGAGGVGKSA LTIQLIQNHFVEEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGF LCVFAVNNIKSFEDISQYREQIKRVKDADEVPMVFVGNKVDLQSRTVETKQGKNLADSYG IPYVETSAKTRQGVDDAFYTLVREIRKYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--VELCQ FSGHKIYPGHGKKVVKVDGKSFLFINAKCEKLHLTKRNPRKISWTVLYRRKHKKGLTEEV SKKRTRRTHKFQRAVAGASLSDILAKRNQKPEVRKAQREQTIRAAKEEKKAKQAAKPRVG GKRMKLNIAYPATGCQKLVEIDDEKKLRPFYEKRMSAEVPADHLGDEWKGYVVRITGGND KQGFPMKQGILTNGRVRLLLKKGHTCYRPRRTGERKRRSVRGCIVDANLAVLALVIIKKG EAEIPGLTDKTIPRRLGPKRASKIRKLFNLGKEDDVRQYVVRRQLPPRSKAPKIQRLITP VVLQRKRHHMALKKKRSDKKRDEAASYAKLLAQRVKEAKERKAERKRSASQSRKVKAKEL RGKAKADLVKQLEDLKTELATLRVAKVTSGAPSKLSKIHLVRKSIARVWTIINQTQKENL RKFYVPKDLRPKKTRAIRRNLSKSEGSAKTSKQLTKERNWPLRKFAVKXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKKKKDVKKFVVD CTHPVEDGIMDCANFETFLKERVKVNNKTNNLKSKIMVESDIPFSKRYLKYLTKKYLKKN NLRDWLRVVANTKESYELRYFQINNEEDEDEGD-XXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSKVVTLEELKSHKDASSLWIAIHDKVYDIT KFLDEHPGGEEVLLEQGGGYGTEAFEDVGHSTDAREIMKDYLIGELAEADKNSWTSWLVP LGIAIAAALLYKF-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------QAVRENRYVVLPKDFEKGYKNNIKKDEQEHEFYKXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--AAKVHINIVVI GHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITI DIALWKFETTKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVASGTGEFEAGISKNGQT REHALLAFTLGVKQLIIGVNKIDSTEPPYSEARFNEIKKEVHSYIKKIGYNPDFVPFVPI SGWHGDNMIKMKWWKGWDAKTGMTLFEALDNIKPPERPTDKPLRLPLQDVYKIGGIGTVP VGRVETGIIKPGMVVTFAPANISTEVKSVEMHHESMPEALPGDNVGFNVKNVSVKDIKRG NVAGDSKNDAPKEADSFKAQVIILNHPGEIRKGYAPVLDCHTAHIACKFTELLEKIDRRS GKSLENNPERVKSGDAAIIDLKPGKPMCVESFQEYPPLGRFAVRDMRQTVAVGVIKSVVK KD-GNVKATKAAQKAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXX---GRIELGDVTHHNIKQLKRLNQVVFPVTYNDKFYKDVI EVGELAKLAYFNDIVVGAVCCREDKSEGQRRLYIMTLGCLAPYRRLGIGTIMLKHVLNLC AQDKQYDNVYLHVQISNDEAIQFYERFGFHIVEKKDNYYKRIEPADAYVLQ-----MPKE IKEIKDFLLTARRKDAKSVKIKKNVKFKVRCSRYLYTLVIQDLEKAEKLKQSLPPGLAVK ELKMSKLSRDNLHECVATVLKKKRKFTESIELQVALKNYDPQKDKRFSGTVKLKHIPKPK LRVCILGDQQHCDEAKAADIQHMDVDALKKLNKNRKLVKKLAKKHDAFLASDSLIKQIPK ILGPGLNKAGKFPTVLSHTESMVNKVDDVKATIKFQMKKVLCLALAIGHVNMEHDQLISN IVLAVNFLVSLLKKNWQNVRSLYIKSTMGPAQRIYMAD-DKLNIGSIIGRLLEVRGSRPG KNGQLTESEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN IKLWKTFTDWFNTLPIAAIIDEKIFCWHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKETMGWGENDRGVSFTFGAEVVAKFXNKHDLDLICRAHQVVEDGYEFFAKRQLVT ------------------------------------------------------------ ---MFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEIVGTNVSTT FITCPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKSVRRRFRASNYQSTTRVKPF ICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDEL PAEFKLYLPIQQAMTALNIQNLQDPFATEQDIHIRIQQRNGRKTLTTVQGLSSDYDLKKI VRVCKKEFACNGTVVDHPEFGEVIQLQGDNRNSIRDFLVQTGIKDKVKVHGF---YSFDG LVVFGLIFICSCAYIKRV-PRLFLSEKKGVWGVFYKGAVIGTRLHIPVAIMCILMAVYIL FL--SRVTSAIRTQLPRVVSQKNAVGAGYVSCRKFTTTAEVSSILEDRILGTADAKMEET GRVLSIGDGIARVYGLNNIQAEEMVEFSSGLKGMALNLESDNVGIVVFGNDKLIKEGDVV KRTGAIVDVPVGEKLLGRVVDALGNPIDGKGAVDQASRQRVGIKAPGIIPRISVKEPMQS GIKAVDSLVPIGRGQRELIIGDRQTGKTAVAIDTIINQKRFNEGSNEKAKLYCIYVAIGQ KRSTVAQIVKRLTDADAMKYTIVVSATASDAAPLQYLAPYTGCAMGEFFRDNGKHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDDFGGGSLTALPVIE TQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQIKAMKQVAG SMKLELAQYREVAAFAQFGSDLDAATQQLLNRGVRLTELLKQGQYEPMAVEEQVAVVYAG VRGHLDKVDPSKIVEFEKAFLEHMRTAQQDTLKSIREAGMITPETETKLKDIVLNFLAGF ---------------------------------------------GGIIYDVMLSLQALX STTDERGNSKPVAFMPYRVNGQYIMEGLASSFLFTLGGLGFVILDQTNKPTTPKLNRILL ISVAGVCILVSFFTCRVFMRMKLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEYAQVQKMLGNG RLDALCFDGVRRLCHIRGKLRKKVWINQGDIILVGLRDYQDAKADVIQKYSPDEARSLKA YGELPENTKLEDNDEENIVFEDIDDILVRFLMKLSHETVTIELKNGTQVHGTITGVDVSM NTHLKSVKMTLKNRDPVQLDSLSIRGNNIRYFILPDSLPLDTLLIDDAPKGRGRGSLMTK PRSDMTPEELAAREQEEFNTGPLSVLTQSVKGNTQVLINCRNNKKLLGRVKAFDRHCNMV LENVKEMWTEVPKTGKGKKKSKPVNKDRFISKMFLRGDSVILVLRNPLPIVIDARGHLMG RLAAIVAKCALQGQRIVVVRCEGLVISGNFYRNKLKYLEYLKLRHNTNPKRGPYHFRAPS KIFWRTVKGMVPHKLHRGKEAMDRLKAFEGIPAPYDKIKRQVVPKALKVLQLKPRRKFAV VSRLAHEVGWKYQSVIQTLEAKRKVKSKRFYTKKRSEERLRLQAKKIAPYQKIIESYGY- GDAKKGKKQFTQKCAQCHTLEAGGKHKVGPNLHGLFGRKTGQAPGFGYTDANISKGVIWG DDTLFEYLENPKKYIPGTKMVFAGLKKKGDRKDLIAYLKEAT-IYVERTLAIIKPNAVCE EIEDIIIRSGFSILQKRRVNLTPEQASDFYAEHYGKLFFPSLVAHMSSGPVIAMILAKEK AISYWRELIGPTNTMKARQTHPDSLRAIYGTDEQRNALHGSDSYSSSEREIRFFFPDSVV EPVPVGQAAKDYLAKAVNPTLLKGLTELCKQKPQDPVIWLADWLVEN--------XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXRATAVNNITKRLHRGQIVSVIGAVVDVQFDAGLPPMLNALEVQG RTSRLVLEVAQHLGENTVRTIAMDGTEGLVRGQVCIDTGYPIRIPVGPQTLGRIMNVIGE PIDERGPIKTASVAPIHAEAPEFTDMSVEAEILETGIKVVDMLAPYAKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVISLKDDTSKVALVYG QMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGAMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIA ELGIYPAVDPLDSSSRILDPNIVGMHHYTTARAVQKI----------------------- ------------------------------------------------------------ -----------------MLMPKKNRVTIYEHLFKEGVIVAKKDFHAAKHPELEVPNLHVI KALTSLKSRGYVKEQFAWRHYYWYLTNEGIQYLRDFLHLPPEIVPATLKRQAGGSDRADY RRNAAGDKKADAGAGANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX MTNTKGYRRGTRYMFSRQFKAKGRHPLSTYFKVYKRGDIVDIKGDGAIQKGMPFKDYHGK TGRVYNVTQHAVGVIVNKRVKGRILAKRINVRIEHVKHSNCRLDFLKRVEKNDQAKKTAR ERVLLKRQPVGPKPGHMVRTQNNKPTMIEPIPYEFIAXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFLTRSEYDRGVNTF SPEGRIFQVEYAIEAIKLGSTAIGIQTSEGVVLAVEKRVTSPLIEPSSIEKIMEVDSHIA CAMSGLIADSRTLIDRARVEAQNHWFTYNEKMSVESVTQAVSNLALAFGDDDADPGAMSR PFGVALLFAGYDENGPQLFHLDPSGTFLQHDAKAIGSASEGAQQALQESYHKSMTLKEAS KEALKILKQVMEEKLNSTNVELANVTTDKKFSLFHKAELEKVIKEIAQKTWEMSNSVETI SSVDEIYRYDKKQQQDILTAKPWEKDPHYFKNIKISALALLKMVMHARSGGNLEVMGLLL GKVDGNTMIVMDCFALPVEGTETRVNAQAQAYEYMAAYTESAKSVKRLENAIGWYHSHPG YGCWLSGIDVSTQMLNQQFQEPFVAIVIDPVRTISAGKVNIGAFRTYPKGYKPPDEGPSE YQTIPL-KIEDFGVHCXQYYSLDVSYFKSA------------------------------ ------------------------------------------------------------ ---GGLPRRIMKETSRLMSEPVPGISAKPDDNNARYFHITVSGPKDSPYENGTFKLELFL PEEYPMAAPKVRFLTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPD DPLANDVAEKWKSNESQAIETARAWTRLYAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPGYGDLG KSARDLFSKGYNYGTYKVESKTKSKDGVEFKATGSSNHDSGKFTGSLETTYSCKDYGLKF VEKWNTDNTLSTEISMEDQLIKGLKLVFEGQFAPQTGKKSGKVKETYKREYFNGSCDVDF DFAGPTINASAVTEYKGWLAGYQMAFDKSKLAKNNFAIGYKGGDFELHTAVNDGTDFAGS VFHKLNKETECGVDLQWTAGKHATKFGMAAKYCPDRFSTYRAR----------------- ------------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMVEH VGTVVAKFYNEYMQSTSSKVKLIDAYLFYIILTGVIQFGYCCLVGTFPFNSFLSGFISCV GSFVLGVCLRVQINPQNKNEFHGISPERAFGDFVFAHVVLHLVVMNFIGXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXVIDHYENPRNVGAMDKKDKTVGTGLVGAPACGDVMKLQIKVDEHG KIVDAKFKTFGCGSAIASSSLATEWIKGKTLDQASTIKNTDIAKELCLPPVKLHCSMLAE DAIRAALKDYQVKNQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXMGRFMKPGKVVLVLGGRYAGRKAVIVKNYDDGTGDKPYGHALIA GVDRYPRKVTKSMGKKKMKMRSKIKSFIKTANYNHLMPTRYSVVAFDKGVVNKDAFTDPA KRRKARGDIKKKFEERYKTGKNRWFFQKLRFXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAD APKPVKSDVKPKEKAVKAKKAVLRGVHEKRNKKIRTSVHFKRPKTLRLPRAPRYPRKSTP RRDRLDQFKIVQYPLTTESAMKKIEDNNTLVFVVDKRANKPQVKLAVKKLYDIQVSKVNT LIRPDGMKKAYVRLASDYDALDVANKIGIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXRLYVKAVFTGYKRGLRNQHEGTALLKLDGVNCLPETDFYLGKRCCYVYKA KKKTACPGHEKPSRLRVIWGKVTRPHGNSGAVRAQFRKNLPPSAMGRRIRVMMYXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPQNEHIELHRKR HGYRLDYHERKRKKESRQAHTLAKKAKKLRGIRAKLYNKKRHSEKIQMKKTIKMHEERNT KQKKEEKVPEGAVPAYLLDREEQSRAKVLSNMIKQKRKEKAGKWEVPLPKVQSQSERDVF KVVKTGKTRRKSWKRMVTKACYVGEGFTRKPPKFERFIRPMGLRFKKAHVTHPELKATFC LPIIGVKKNPSXSLFTSLGVITKGTVIEVNISELGL------------------------ -------MAARPLISVYSEKGEATGTNVTMPAVFKAAIRPDIVSFVHSEMKKNGRQPYAV SEKAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRR INVNQRRYALCSAIAATGIPALVMSKGHRIEQIPEVPLVLSDKVEEIKRTKEAVGVLRKL KAWDDIEKVKNSRRFRAGKGKMRNRRRIQRRGPLVIYSKDNGITKAFRNIPGITLLPVER LNLLKIAPGGHVGRFVVWTESAFKKLDGLYGTWKTASKEKTNYNLPMAKMTNTDLSRLLK SDEIQSVIRAPKRVRKVASIKKNPLKNTRVMNRLDPYAKVLRKSRQRKAARQAKQDAARG IATVTTGGKSRPRKII-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXMSHTILLVQPSSKPEGRTYSDYETVNEMLEGVCKIYEEYLKRMNPNSPSITYDISQ LFDFVDSLADLSCLVFEKVSGKYTPHNKAWIKEKIYILLRKQAGKMAEEGGEKKQEETKR VVHTYPLVRHSDMNEEMRTEAMELCVTACEKFSTNNENAAKFIKETMDKKFGASWHVVVG EGFGFEITHEVKNLLYMFFGGNVGICLWKCSMSHRKFSAPRHGSLAFLPKKRSRRHRGKC KAFPKDKPDQPVHLTAFLGYKAGMTHIVRDVDRPGSKTHKKEVVEAVTIIEAPPMVCVGL VGYIETPRGLRTFKTIFSEHLSEECRRRFYKNWYRSKKKAYTKANKKWTDDLGKKCLEKD FNRIKKYCKVIRVICHTQMKLMKKRQKKAHLMEIQLNGGXLPQKVDWAREQFEKTIPMKQ VFAEDEMIDIIGXTKGKGVKGVTSRWHCKKLXRKTHKGLRKVACIGAWHPARVGFSVARA GQKGYHHRTEINKKIYRIGEGIHTKDGRVVKNNGSTSYDITEKSITPVGGFPHYGEVNND FMMVKGCCVGPKKRVITLRKSLLTHTKRVALEKISLKFIDTSSKFGHGRFQTPEEKAAFM GPLKKDMQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLG LWDTAGQEDYDRLRPLSYPQTDVFLICFSLISPASFENVRAKWYPEVSHHCPNTPIILVG TKLDLREDKETIEKLKDKKLSPITYPQGLAMAKEIGAVKYLECSALTQKGLKTVFDEAIR AVLCPKPNPKKKKRCIILXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQVPETLLKKRKQAEERNKEKRSIIFKRAE KYVKEYRIQERDEIRLKRQAKKADNFYVPSEPKLAFVVRIRGVNGLHPKPRKVLQLFRLL QINNGVFIKLNKATLHMLRIAEPYIAWGYPNLKTVRELIYKRGYGKIQSRRTPLSDNNII EQALGKEGIICMEDLIHEVFTVGPNFKRTTNFLWPFKLNTPNGGWRRKTNHFVEGGDHGN REDKINALLRKMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX-----LLRAKLLVVGDSAVGKSAITQVFHSDGFPKTYSMTIGVELCTKSVTVPDNSV ELFMYDSAGKEMFTDQVMKHWDHPSLVMVVYDCTNETSFNSCTKWLERVRNQKGARVPGV VVCNKVDLDQRRMISQKEGEDFAQQMGLEYFECSAKEMQSVDQPFHYLAKA--------- -----------------MGIKYNLAVGLNKGHKTTVQRPRPSRRKGALTKRSKFIRDTIR EVCGFAPYEKRMMELLRIQKDKRCLKFAKKRLGAHVRGKRKREEMQGVIQAMRKAXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLLDKFEFLDDVRRMNKRQLYYQ CLNFAMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNHRADPIRVGD IVVFKIEGREIPIVHRVLKVHEKENGSVKFLTKGDNNSVDDRGLYAPGQLWLEQKDVVGR AKGFVPYVGIVTILMNDYPKFKYAVLALLGIFVLIHRE---MNPEYDYLFKLLLIGDSGV GKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYR GAHGIIVVYDVTDQDSFSNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEF ADQLGIPFLETSAKNATNVEQAFMTMAAEIKNRMGPQSAAPNVKINASTPVKTNGGGCCX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------VPGRRGFPGYMYTDLATIYERAGRVEGRSGSITQIPILTMPNDDITHPIPDLT GYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTREDHSEVSNQLYACYAIG KDVQAMKAVVGEEALSPEDLLYLEFLGKFEKNFIAQGHYENRTIFETLDIGWQLLRIFPK EMLKRIPESTLKKYYPRDGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXKPTYKVADISLADWGRKAIEIAENEMPGLMQMREKYGPSKPL KGARIAGCLHMTVQTAVLIETLMELGAECTWSSCNIFSTQDHAAAAMAARGIPVYAWKGE TDEEYMWCVEQTLVFPDGQPLNMILDDGGDLTNLVHEKFPQYLKDIKGLSEETTTGVHNL YKMMEKGQLKVPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGKVACVAGYGDV GKGCAQALRAFGARVIVTEIDPINALQAAMEGYEVSTIEDALPRARIFVTASGCKDIIKG DMFAKMLEDTIVCNIGHFDCELDVKWLNDN-AKKETIKPQVDRYTLPSGKHVIMLAEGRL VNLGCAMGHPSFVMSNSFTNQVLAQLELWGHKSNYEIGVHFLPKKLDEEVAAAHLDHLGV KLTKLNTDQATYLGIPQAGPFKPEHYRYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------- ----GLQINKHRTIHAAASGPSCEFGSSKYYALCGFGGLLSCGLTHTAVVPLDLVKCRIQ VDPAKYKNIFHGFKITVAEASMKELAKGWAPTFIGYSMQGICKFGFYEVFKNLYGGLIGE ERSFTWRTSLYLAASASAEFFADIALCPMEAVKVRIQTMPGFANNLREGFPKIYNAEGIN GFYKGLVPLWSRQIPYTMMKFACFERTLEALYKYVVPKPRNECTKREQLVVTF------- ------------------------------------------------------------ -------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--RRNRPGTKLENWCSWPDEQYEEMDSTL ATQQFIQQAIRRDFTNIDEILSPPESQDEGVWKYEHLRQFCMELNGLAVKLQAECNPETC TQMTATEQWIFLCAAHKTPKECPAIDYTRHTLDGAACLLNSNKYFPSRVSIKETSVAKLG SVCRRVYRIFSHAYFHHRALFDEYENETALCKRFTTFVTKYNLMSKDNLIVPILDEQMPN IKLQSSDGEIFEVDIEIAKQSVIIKTMLEDDDEEEEAVPLPNVNSAILKKVIQWCTYHKD DPPPPEDDENKEKRTDDISSWDSEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMI KGKTPEEIRKTFNIKNDFTPAEEEQVRKENEWCEEKNKRPVKGGKKGGKKKVVDPFSKKD WYDVKAPSMFAVRQVGKTLVTKTIGTKIASDGLKGRVFEVSLADLQNDEIAFRKFKLMAE DVQGRNVLTQFHGMDLTTDKLRSMVKKWQTLIEANVDVKTTDGFLLRMFCIGFTKKRPNQ IKKTCYAQSAQVKNIRKKMTDIMSREVSTNDLKEVVNKLIPDSIGKDIEKACQGIFPLHD VCIRKVKILKKPRFDLTKLMEVHGEG--------------------------XXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------- ------------------------------------------------------------ ----DDDDDFDLFGSEAEKIKQERLAAYAARKKPGIIAKSNIILDVKPWDDETDMKVLEE HVRSIEQDGLLWGAAKLVPVGYGIKKLQISCVVEDDKVSTDDLEEKICAFEDFVQSMDIA AFNKVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGVEVETTKPGDGTTFPKKGQTVIVHYTGTL TNGNKFDSSRDRNKPFEFKIGAGQVIKGWDEGVAQMSVGQRANLTCTPDYAYGARGYPPV IPPNSTLIFDVELLGLKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXAVCLLGTVLADPTVYFREEFYESRWVESTHKGAEQ GKFKWTAGKFFNDEDKDKGIQTSQDARFYGLSSKFDS-FSNEGKTLVVQFTVKHEQNIDC GGGYLKIFSSDLEQGDMHGDSPYNIMFGPDICGPGTKKVHVIFNYKGKNLLVKKDIRCKD DVFTHLYTLIVRSDNTYEVKIDNKKVQDGSLEEDWDFLAPKKIKDPEAKKPDDWDDREKI DDEDDTKPDDWEQPEHIVDPDATKPDDWDDEMDGEWEPPMID--DYKGDCKPKQIPNPNY KGPWVHPEIDNPEYVADDSLYKYSDFGAIGFDLWQVKSGTIFDNILITDDEDFAAEVGDE LWGVTAEGEKKMKDEQDEEERKAREAEGGDEEDEDMDFD-----XXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNIFRLIGDLSHLTAIILLVIKI WKTRSCAGVSGKSQIMFALVFTTRYLDLFTSFISLYNTSMKVIFIVMSYATVYLMYAKFK ATYDSNHDTFRMEFLIVPVAGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGE AESITSHYLFALGSYRALYILNWVYRFYFEGFFDLIAVVAGCVQTILYCDFFYLYITKVW KGKKLTLPAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------RKIIVDTYGGFPFH GGGAFSGKDFSKVDRSAAYAARWVAKSLVKAGLCRRVLVQVAYAIGVAQPLSVFVNSYGT G--DDAKLLKVVNENFDLRPGKIVMDLDLKKPIYQATASYGHFGRNEFSWEQPKKL--XX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMRVEKCFFCSSNIYPGH GTAFVRNDSQVFRFCPAKCNKAFKKKRNPTKVKWTKAFRKARGKELTVDPAFEFEKRTHV PVKYERGLWNNTVKAMKRIDEIKLRREGQYIKNRLKKGKELRKASDIKEVEKNIHLIKSP A--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------NFLAIAKTILKRLFRVYAHIYHQHFQQVIQLAEEAHLNTSFKHFIFFVQQFGLV DKRELAPLRELIEKLTKDKMGIDINHKHDRKVRRTEPRSNDIYLRLLVKLYRFLARRTNA KFNKIILKRLFMSKINRAPLSIARLTRYMKKDGRSDKMAVCVGTITDDVRLFEVPKMKVC ALHVTERARARILKAKGEIITFDQLALRSPKGQNTVLIQGPRKAREAQRHFGKPPGVPGG HAKPHVRSKGRKFERARGRRKSRGFK-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKSPEPVEGRKHIDVQT ELYLEELSDRVEEADVEVQTDAFLDRPPSPMFIPAKTGQDVTTQIMEGDLFDFDIEVKPI LEVLVGKTIEQSLLEVMEEEELSNLRAQQRAFEELRNAELVEQQRLEEQEARHREEKERR MKQQREILRKERETSDKIAARAFAQSYLSDLVPSVFGTLSDNGYFYDPVERDVEQGFIPW LMDQVTEKIQRANAGRIVLDGIIREVVKTRQDAF---RARGDLKEYKVVGRAFPTDKNPT PALYQMQLFAPDKPSAKSRFWYFAALLKKMKKSLGEIVFCEQVFEKRPTSIKNIGIWLRY QSRSGIHNMYREYRDLTTAGAVTQCYRDMGARHRARSSAIQIIKVEKVPASKCRRPNIKQ FHDSKIKFPLTHRVTKRRGAPLFTTTRPNTRFXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMIIFKDIISDKEVLSDIFKKQIIKVVGKDDSMFGGNKSSGVDCLMNTKKQFLVYLKE KMKDVTEFQFFLNVNFVIWSDPICYYVKEALIPEK-XXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXMSIMAYNGAAVIAMKGKDCVAIASDKRFGIQGQTVGMDTDKIFEVGQKLYV GLPGLYTDSLTLSQRLRFHVKMYQLRENRQMKPKTLMSLVSNMLYEKRFGPYFIEPVIAG LDPKTNEPYVTSMDLIGCPMETEDFVVSGTCNEQMYGMCEALWRPDMGPDELFEGISQAL LNAVDRDA--------------------------MTSKDYYFDSYAHFGIHEEMLKDEIR TLTYRNSIYHNKHLFKGKVVLDVGSGTGILCMFAAKAGARKVIGIECSGIVDHARQIVKD NKLDHIITLIKGKVEEVELPDGIEKVDIIISEWMGYCLFYESMLNTVIYARDKWLTPEGA IFPDRATLYVCAIEDRQYKDDKINWWDNVHGFDMSCIKRVAIQEPLVDVVDPKQ------ ------------------------------------------------------------ ---------------------------------------------------------MVK EDRSTWKANYFVKIIELLNEYPKCFIVGVDNVGSKQMQTIRQSLRVLMGKNTMIRKAIRG HLEQNPQLERLLPHIKGNVGFVFTKDELTEVRDMILSNKVSAPAKAGALAPIDVIVPAQN TGLGPEKTSFFQALSIQTKIARGTIEMLSDVKLIHAGERVGASEATLLNMLKISPFFYGL QIQQVYDSGTVFSPAILDLTNEDVISRFMQGVTNVAALSLAIGYPTVVSVPHSIVNGFKN LLAIAAETEITFKEAETMKEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXX--------------DEKWLRWMQKQFEEIAGDD-GEIDLNE FKGALGVKKSFFAERFFQLFDQDKSGSIELQELMDGLHMLT-KGSPKQKLKFLFDVYDID GSGNIDPEELKNVLKSSMEESLPEEKLQELTDTLFEAADEDNSGEITFDEL---VSELDK H-------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSRMKVKQIGGEKNGGKR 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------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --HVVVMAATNRPNSIDGALRRFGRFDREVDIGIPDSTGRLEILRIHTKNMKLADDVDLE QVAAETHGHVGSDLAALCSEAALQQIREKMDLIDLEDEQIDAEVLDSLAVTQEDFRWALG KSNPSALRETAVEVPNVSWEDVGGLENVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFY GPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFD ELDSICKARGGNAG---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------GGGSTFGTTTVFGASNNVNPMKDFEVTSPPDDSVSCLKFSPGILPSTFLVAG SWDNNVRCWEVQPNGQTVPKAQQTHTGPVLSVDWSDDGTKVFTGSCDKTAKMWDLNSNQA IQVAQHDAPVKTVNWIKAPNYTCLMTGSWDKTLKFWDTRTPTPMRTIQLAERVYCADVLY PMAVVGVAGRRVHIYQLENQPQEFKSMESPLKYQHRC----------------------- ------------------------------------------------------------ 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXX---------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------FLPPTSAMGAGMYSVAVY GGLILFGMFLLYDTQKIIKRAETTPVNSVRQYDPINNAVSIYVDTINIFVRMVSILAG-- ----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXWDVLVSRIQPIA NPLASRKLNKRLFKVIKKALTKGQRDVQKALRKGQQGLIVLAGDTEPLDVIVHLPGLCEE KGLPYCYTPSRQELGLATGTKRSVCVVMVKSQEDYKELYDEVLSDVTALPLPVMPLESFE EEGLAKIPNLELAQFKFLLKTEKFKDDPKIKRDLFEAIKADKMAPFYEDVCQDLGWTLDT ALLQEMKSTNEDKMKVLDEKVEDAEKNLGDTEVRDFMLAKGELLVRTGAKEEAVTQFRKT AEKTVTTGYKLDMVFHQLRLGLFYMDHDLIKRNLEKAQTLIDEGGDWDRRNRLKVYRGLY CMAIRDFKTAANLFLDTVATFTSYELMEYKTFIIYTVLSSMIALDRPDLRTKVIKGSEIL EVLHSLPDIRSIVF---------------------------------------------- ------------------------------------------------------------ ----------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XX---------------------------------------------------------- EESSCMQRCCCGALRKFVMHVADNTGREVMRFRREFSCS-YCCCIPCCASEMVVEAPPGN IIGFVKQECWRLTMGIYDDVAVINGPWCACTWCCCPSDIDYPITSMDVGVIAKQWAGCAR ECF---------------------------------------XXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXCKYFATEFKNRLAESAKSKEVLETGHGLDKKKRFAYLTSDLRLIEALQDPHIC ERILEYNVHAEREGSLRYEKGMSETFETLHGLVDKGVKVELGIPYEMWDQPSAEVSKMHR ACFRLAEEYEEDIEDWYYHHQEDFVSYLCEKRYLK----XXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMG DVLNFGVEPISCYAWNGNRTKVAIHNNNEVNIYAVRHELECTLSEHTQRVTGIDWGATNN LIVTCSADRNAYVWPLLVILRINRAATCVKWSPKEDKFAVGSGARLISVCYFEQENDWWV SKHIKKPIRSTVTCIDWHPNNILIACGSTDFKARVFSGYIKEIEDKPEATVWCKKMTFGN MMAEFSNGGGWVHDVSFS------------------------------------------ ------------------------------------------------------------ -----------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------YIQAQELYANLTREQADYCIKRMKPYTDPKGRVMPDAYDFVE FTQDVFINAIQCYQCDSNEDAACPSNKQFDRNLNALVDCNSFEAHVPGTFCMKVSQQSPG WRAWKKVTRRCGSRSDTGVAWGCKWVYEDNGVWKETCYCEDKDGCNSASGXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------- ------------------------------------------------------------ --------------------TTSVVIIAAELLKRANELVKQKIHPTSVISGYRLACKEAV KYIKDNLAVGTDSVGASALLSAARTSMSSKIVSAEGDFFAQMVVDALLRVKQTSARGKVR CPIKAINVLKCHGKSAAESLFIPGYALNCTVSSQAMPKCIKGAKIACLDFNLQRHKMSHG VSVLVTDPTKIDKIREREADITKERIQMILKSGANVVLTTKAVDDLCAKYFVEAGAMAVR RVRKQDIRQIAKATGATLLASLASIDGDESFEPAMLG----------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXX------------------------------------ ------------------------------------------------------------ ------------------------------------------------RLTKAIGKSKAM EMVLTGDRINAQEAEKAGLVSKVFAPDQLVAESLKTAEKIAGHSKVVTMMAKEAVNASFE MSLNEGLKYEKRFFHMTFGTEDRKEGMTAFTEKRAPNFTD >Pristina_leidyi MTERKAVIKNADMSEDMQQDAVDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSGSVTPARLFQTSATRNDIDQAAKYIGAGAATV GVAGSGAGIGSVFGSLVIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLILFAF- -------------------------VKSLEKVCADLIRGAKDKQLKVKGPVRMPTKTLRI TTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADMDQVM QYVEPAKQFTKDSIRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNII V--------RKFVQEGVFKAELNEFFTRELAEDGYSGVEIRVTPTRTEIIILATRTQNVL GEKGRRIRELTSVVQKRFNFPEGSVELYAEKVGTRGLSAIAQAESLRYKLIGGLAVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPMNDYVDQAVRHVLLRQ GVLGIKVKIMLPWDPSGKIGPKRPLPDHVSILDPKDQPAPEQPYSEQKGAKMSKRGRGGS SGGKFRISLGLPVGAVINCADNTGAKNLYIISVHGIRGRLNRLPAAGSGDMVMATVKKGK PELRKKVMPAVVVRQRKAIRRKDGVFIYFEDNAGVIVNNKGEMKGSAITGPVAKECADLW PRIASNAGCIRKQKVAKVTLGPQLAEGENNFGVAHIFASFNDTFVHVTDLSGSETIVRVT GGMKVKADRDESSPYAAMLAAQDVAERCKALGITALHIKLRATGGNRTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL--KPKGIRTARKLKKHRQEQRWNDKR YKKXNLGTRWKADPFGGACMAKGIVLEKIGVEAKQPNSAIRKCVRVQLIKIXQKITAFVP NDGCLNFIEENDEVLVSGFGRSGHAVGDIPGVRFKVVKVANTSLLALXRGKKERPRSDAA ATIRTRKFLTNRLLNRKQMVVDILHPGRATVPKTEVREKLARMYKTTADVVFCFGFRTNF GGGRTSGFALIYDSLDLAKKIEPKHRQARHGSRKQRKERKNRQKKVRGTKKAKVGAMPRI PLVTSKTYSTPRRPFEKERLDQELKLIGEFGLRNKREVWRVKYALTRIRTAARELLTLDE KDSRRLFEGNALLRRLVRIGVLDESKMKLDYVLGLRLEDFLERRLQTQVFKLGLAKSIHH ARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLKSPYGGGRPGRVKRKNQRKATGGG GGMGNIFEKLFRGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVGEAREELMRMLAEDELRD AVLLVFANKQDLPNAMNAAEITDKLGLHSLRQRNWYIQATCATSGDGLYEGLDWLSNQLK NQKMPLYRDLLHPSIEDEKRKCKLKRLIQSPNSYFMDVKCPGCYKITTVFSHAQTVVVCA GCSTVLCQPTGGKARLTEGCSFRRKQHMVRMNVLADALRSICNAEKRGKRQVLIRPCSKV IVKFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRINKCSVISPRFDVKIKDLEHWSAYL LPSRQFGYIVLTTSGGIMDHEEARRKHLGGKILGFFF------PRKGISQSSLPYRRSVP TWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKAKGLAAQ IPEDLYFLIKKAVAIRKHLERNRKDTDAKFRLILVESRIHRLARYYKTKKVLPPNWKYES STASTLVAIAELPQIKLFGRWSSDDVNHSDMSLADYIAVKEKHAKYLPHSAGRYQAKRFR KAQCPIVERLTDSLMMHGRNNGKKLMAMRIVKHAFEIIHLLTNENPLQVLVNAVINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAISLLTTGAREASFRNIKTIAECLADELINAAK GSSNSYAIKKKDELERVAKSNRMTEQMTLRGTLQGHGGWVTQIATTPQNPDIIISSSRDK SLIVWKLTRDSSYGVPFKSLRGHGHFVSDVILSSDGQFALSGSWDHTLRLWDLSSGQTTR RFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIEDCHSDWTSCVRFSPNT QNPIIVSCGWDRLVKVWNLTNCKLKTNHYGHTGYVNTVTVSPDGSLCASGGKDSQAMLWD LNEGKHLYTLDGTETINALCFSPNRYWLCAATGPTIKIWDLEGKVVVDELRPEVMGNTGN PPTCLSLAWSADGQTLFAGYTDKLIRVWQVSMVSR----KLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKVVEIEGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTFNDLQDLRMQILRVKDTEDVPMILVGNKCDLEDERVVGKLARNWNSAFL------- ---------------------MTEEKK-SDEHINLKVTGQDGSVVHFKIKKNTPLRKLMS AYCERTGVKMGSMRFRFDGQPINETDTPAGLDMEDGDAIDVFQQQTGGMSTLPLNPKPFL NGLTGKPVIVKLKWGMEYKGYLVSVDGYMNLQLANTEEYIDGALSGNLGEVLIRCNNVLY IRGVAEEDEEGEMREMSDTEGDDVPAASVATGSMDVNTAIKEVLKTALIHDGLARGLHEC AKALDKRQAHLC--------------------------------------------DKEG KARKVVGCSCVVVKDIGKESQAWDVLNEYFKTHKMAAIRKKLVIVGDGACGKTCLLIVFS KDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSI DSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEATKRELMKMKQEPVRPEDGRA MAEKISGYAYLECSAKSKEGVREVFETATRAALQTKKKKKAVMDDFQTGEETTFVVDEVS NIIKEAIEGAIGGSAYQHNKVNPWTSNVVEQCLNQLAKLGKPFKYIVTCVIMQKNGAGLH TASSCFWDNTTDGSCTVRWENKTMYCIVSVFGLAIMYSASAKIVKPQGEKPDEFESSISQ ALLELEMNSDLKAQLHDLTFTAAKEYDVQNKKVIVIFVPYPQLRAYQKIQTRLVRELEKK FSGKHVVFIAQRRILPKPTRKMRRKNKQKRPRSRTLTAVHDAILEDLCFPSEIVGKRIRV KLDGTRLIKVHLDKAQQTNVEHKLDTFTAVYKKLTGKDVVFEFPDCVLGRGGFRGGFGGR GRGRGRGRGRGKEGDKEWVPVTKLGRLVKDLKIKTLEEIYLFSLPIKEFEIIDHFLGSTL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDFNGHVGLGVKCSKEVATAIRGAIILAKLSI VPVRRGYWGNKIGKPHTVPCKVTGKCGSVMVRLIPAPRGTGIVSAPVPKKLLHMAGIDDC YTAASGQTATLGNFAMATYHAIANTYSYLTPDLWKETVFVKSPYQEFTDYLSKMSGGHEA LALHEDDVTKFLACGTHLGSNNLDFQMEQYVYKRKPDGGYIINLRKTWEKLLLAARAIAA IENPADVCVISARPYGQRAVLKFSSYTGATPIAGRFTPGTFTNQIQSAFREPRLLVVTDP RQDHQPITEAAYVNIPVIALCNTDSPLRYIDIAIPCNNKTVHSVGLMWWLLTREVLRLRG SISREVPWEIMVDLYFYRDPNEEQTKPQEANWGESIAVAPPAIASKDWSATDTGDWAASS TASDWGGMKFNKAVTSSRRKNRCRHFNAPSHIRRRIMSAPLSKELRQKHNVRSIPIRKDD EVQIVRGHHKGQQSGKVVQVYRKKFVIHIERIQREKVNGATVNVGIHPSKVVITKLKMDK DRKAILERKAAGRQKGKHTEESI---SSTPVGTTVRHRKTPTAAGGSAGMWRFYTEDSPG IKVGPVPVLVMSLLFIASVFMLHIWGKYTRGKKEGKKKAVTNEVVTREYTINVHKRVHGI GFKKRAPRAIKEIRKFAEKMMGTPDVRIDTRLNKHVWSQGIRHVPHRVRVRLARKRNEDE DSPNKLYTLVTFVNVATFKGTQTVNVES----------KYRLIRKIGSGSFGDIYLGINV SNGEELAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGEKDYNVLVMDLLGPSLE DLFNFCGRRFSMKTVLMLADQMIGRVEYVHNKNFIHRDIKPDNFLMGIGRHCNKVFLIDY GLAKKYRDNRTRQHIPYREDKNLTGTARYASVNAHLGIEQSRRDDMESLGYVLMYFNRGS LPWQGLKAATKKQKYEKISDKKMSTPVEILCKGYPAEFAMYLNYCRGLRFEEXPDYMYLR QLFRILFRTLNHQYDYVFDWTILKQKATGAMNAEKLKQRIGGKGSARRKKKVIHRTNTTD DKKLQVSLKKLGLTTIPGIEEVNMIKDDGEVIHFNNPKVQASLAANTFAVTGHAEIKQIT EMLPSILSQLRAENFSSLKKLATSAADAE-DDEDVPDLVENFDEASKNEMTRYSVDAENA SKSAKARGSHLRVHFKNTRETAQNIKKMHLRRAVAYLKNVVNHKECVPFRRFTGGVGRCA QAKVWGTTQGRWPKKSAEFLLQLLKNAESNAEFKGLDTDHLVIEHIQVNRAPKMRRRTYR AHGRINAYMSSPCHIEVILAEKEQAIAKPGKKKVSQKKLKKQKMMMRE------------ -------------------------------------KEEIKKMIAEIDKEGTGTIDFND FLTMMTIKMSEKDSKEEIMKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQEADRD GDGEIN------------------------------------------------------ ---------------------------GSEAVTRKTRIIDVLYNASNNELVRTKTLVKNC IISVDCTPFRTWYEAHYALPLGKKKGAKLSAEEEARINKRSKKAQRKYEKRKKNAKVEPA LEEQFASGRLLACVSSRPGQCGRCDGYILEGKELEFYMRKIKAKKGKMSLVLPEKFQHIL RVMNTNIDGRRKVAFALTAIKGVGRRYSHVVCRKANVDLSKRAGEMTDEEVDKLVTIMSN PRQYKIPDWFLNRQKDIKDGKYSQVMSNTLDSKIRDDLERLKKIRAHRGLRHFWGLRVRG QHTKTTGRRGRTVGVSKKKGSATESD-DESAPEATDVAQAAGLPEELVSKAKQSRSEKKA RKAMSKLGLKQIPGVSRVTVRKSKNILFVISRPDVYKSPASDTYIVFGEAKIEDLSQQAQ MAAAEKFKTDEEVDESGIEPKDIELVMSQASVSRARAVKALKNNQNDIVNAIM-GRVRTK TIKKASRVIIEKYYTRLTLDFHTNKRICEEIAIIPSKKLRNRIAGFVTHLMKRIQKAPVR GISIKLQEEERERRDNYVPEKSAIDEIDPDTKEMLKLLDMAHIPNLQVTLPTPAAMRWEY KEENTFEKRRAEGEKIRRKYPDRVPVIVEKSPKARVSDLDKKKYLVPSDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGALYQEHHEEDFFLYIAYSDESVYGMRELRILKL CLNICVGESGDRLTRAAKVLEQLTGQQPVFSKARFTVRSFGIRRNEKIAVHCTVRGAKAE EILDRGLKVREYE---------------------------------GMDFYVVLGRAGYN VPKKRRARGVIGNKHRGSKDEAMKWFQQKYDGVILPAK---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AFYRSHLPNLMNLLATVFVFCIVIYFQGFR VDLPITSARYRGQQSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAAKFSGNFIVNLLG VWSDSEGGGPARSYPTGGLCYYLSPPETLRHLVDDPIHGVLYIVFMLGSCAFFSKTWIDV SGSSAKDVKKQLQEQQMIMRGHRVSSMEKELNRYIPTAAAFGGLCIGALSVMADFLGAIG SGTGILLAVTIIYQYFEIFVKEQSEMGGVGSMFFQTERAFQKQPAVFLNKKKALLPRHVR NVGLGFKTPREAVEGHYIDKKCPFTGNVSIRGRILTGVVLKMKMQRTIVIRRDYLHFVRK YERFEKRHKNLSVHLSPCFRDVEIGDIVTVGECRPLSKTVRFNVLKVSKGSGSKKAFQKF MVNVPKQRRTFCKGTKCRKHTLHKVTQYKKGKDSLFAQGKRRYTRKQSGYGGQTKPIFHK KAKTTKKIVXKMECTECKFKKQLPIKRCKHFELGGDKKKKGQMIQFMGRVIRSQRKGAGG IFRAHTKHRKGAPKLRAVDFAERHGYIKGVVKDIIHDPGRGAPLAKVMFRDPYKYKQRVE LFIAAEGMHTGQFLYCGKKANLHVGNVLPVGAMPEGTVICNLEEKSGDRGRLARTSGNYA TVISHNPDTRRTRVKLPSGTKKVIPSNNRAMVGIVAGGGRIDKPVLKAGRAYHKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGKASTVARDKSAGKKVGLIAARRTGRXRGTKQVTG KAKRTKKVGIVGKYGTRYGASLRKDIKKMEVTQHGKYTCSFCGKETMKRKSTGIWSCKSC RKVVAGGAYVYSTTAAATVRSTIRRLKETKE-------------NKPYPKSRFCRGVPDP KIRIFDLGRKKAKVDEFPLCIHLVSDEFEQISSEALEAGRICANKYLVKFCGKDAFHLRV RLHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVDIGQIIMSVRAKDTHKEKVI EALRRAKFKYPGRQKIHVSRKWGFTKWDREVYEGMRADGRLVPDGVNVQYKPNRGPLSHW MAAQKVTKILGRTGSQGQCTQVRVEFLDESNRSIIRNVKGPVREGDILTLLESEREARRL RMTKGTSSFGKRHNKTHTLCRRCGGRCYHIQKKTCSRCGYPAKRMRKYGWSEKACRRRTQ GVGRMRHLKKVYRRFRNGFREGTVAKKIKA------------------------------ -LCDKAREILAKESNVQEVKCPVTVCGDVHGQFHDLMELFKIGGKSPDTNYLFMGDYVDR GYHSVETVTLLVALKVRFRDRITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDSQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHSNRLTLVSRAHQLVMEGYNWSHEKNVVTIFSAPNYCYRC GNQAALCELDDSLKYSFLQFDPAPRRGEPHVTRHTPDYFLMGAYKYMQELYRKKQSDVLR FILRIRVWQYRQLAAIHRASRPTRPDKARRLGYKAKQGFIIYRVRVRRGGRKRPAPKGQV YGKPKSVGINQLKNQRSHQAIAEERVGRKIQSLRVLSSYWVGQDSSYKYFEVVCVDPFHN AVRRDPEVQWICKPVMKHREMRGLTSSSKKSRGLGKGHGYSKTIGGSRHANWKRRNTLEL RRKRGIAIGRLSEERKAWRKDHPFGFVARPTKAADGTLNLMNWECGIPGKKGTPWEGGLY KLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSLLDEEKDWRPAVTIKQILLGIQE LLNEPNIKDPAQAEAYTIYCQNRAEYERRVREQALRFRDQSVGKSSKMLQHINYRMRCTL QDGRTFIGTFKAFDKHMNVILGDCDEFRRVKPK-SKTREEKRALGLVLLRGENLVSMTVE GPPPAEEGIARVPIPGAAAGPGIGRAAGRGVPS--GLGGPARGVGAPPPQMMQPQPGMMR GPPPDNIPSFKLVLVGDGGTGKTTFVKRHLTGEFEKKYIATLGVEVHPLVFHTNRGPIRF NVWDTAGQEKFGGLRDGYYIQGQCAIVMFDVTARITYKNVPNWHRDLVRVCENIPIVLCG NKCDVKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLTGDPNLEFVAMPA LAPPEVEMDPAMAMKYEQELQVAQQTALPDEDDDLNDGIKQYYTSKIEELQLVVADKTQN LRRLEAQRNELNAKVRMLREELQLLQESGSYVGEVVKAMDKXKVLVKVHPEGKFVVDVDK NIDINDVTPNCRVALRSDSYTLHKILPNKVDPLVSLMMVEKVPDSTYENVGGLDKQIKEI KEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ KFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRLEGGSGSDSEVQRTMLELLNQLD GFEPKQNIKVIMATNRIDILDSALLRPGRIDRKIEFPAPNEEARLDILKIHSRKMNLTRG INLRKIAEMMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFELAVAKVMQKDNEKNMSI KKLWKLGFAENFMLSGAAAIISKTAAAPIERVKLLVQNQGEMLKSGRLDRPYNGVIDCTV RTFRSEGILPFWRGNLPNCIRYFPTQALNFAFKDQIKAMFAFKKTDPYAVKFTKNVVSGG VAGAMSLVFVYSLDYCRTRLASDAKAGKKRQFNGMIDVYTKTIKSDGFVGLYRGFVISCV GIIVYRGCYFGFYDTLKPMLLGEDAGIVLSFALGYVVTITSGLISYPIDTIRRRMMMTSG EAVKYKGSLDCGITIIRQEGFMALMRGAGANILRGVAGAGVLAGFDKFKALYVQWRVMSD ISDLDRQIEQLHKCEIIKESEVKALCAKAREILAEESNVQRIDSPVTVCGDIHGQFYDLK ELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQV YGFYDECLRKYGSITVWRYCTEIFDYLSLSAIIDGTIFCVHGGLSPSIQTLDQIRAIDRK QEVPHDGPMCDLLWSDPEDTQGWGVSPRGAGYLFGSDVVQQFNTANSIDLICRAHQLVME GYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKNFTIFEAAPQEQRGKPQADYFL VRLPPEVNRILYIKNLPYKITGDEMYDIFGKYGAIRQIRVGNTPETRGTAFVIYEDIFDA KNACDHLSGFNVCNRYLVVLYYQPNKSYKKVDQVKKADELDKMKAKYGLSTPE--MSIGV PIKILHEAEGHVVTCETNTGEVYRGKLVEAEDNMNCQFASVHVTYRDGRTAELENVYIRG SKXRFMILPDMLKNAPMFKKIGAGRGKXAILRA-ARGGGRGGGGGGGGGMQNDAGEYVDM YIPRKCSFSNRIISAKDHAAIQINLVEVDEHTGRLKGQFKTYAICGNIRRMGESDACLNF LGQRDGLVSKMVRGPKKSLKRINAPKHWMLDKLGGVFAPKPSCGPHKLRECMPLAIFLRN RLKYALNYDEVKKIVHQRLVKVDGKVRTDKTYPAGFMDVVTIDRTGENFRLIYDVKGRFA VHRITPEEAKYKLCKVKKTLVGLKGVPSIVTSDGRTIRYPDPLIKVNDTVRIMGTREDEY DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIVVDGKRIKAQIWDTA GQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLRELRDHADDNIVIMLVGNKSDL RHLRAVPTDEAKAFAEKNXLSFIETSALDSSNVEXAFQHILTAIYKIVSRKLVSEHMEGS FSSPRVTLPTSSAITDK-----MSSTYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVC GKDIVVLGVEKKATAKLQEERTVRKIATIDDHVSLAFAGLTADARILINRARIECQSHKL TVEDPVTLEYITRFIAQLKQKYTQSNGRRPFGLSMLIMGFDGTPHLYQTDPSGTYFEWTA NAIGRSAKVVREYLEKHYTSELVSEKETIKLALKALLEVVQSGSKNMEVAVMRRGERLEM LKSDALDEYMREIEKEKEEEAEKKK--GSGQGGDKKDDKDKKKKYEPPVPTRVGKKXKKL KGPETANKLPQVTPHTRCRLKLLKLERIKDYLLLEEEFIKNQERLKPQEEKQEEERSKVD DLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDQLEPGCSVLLNHKVHAVV GVLSDDTDPMVTVMKLEKAPQETYADIGGLDQQIQEIKESVELPLTHPEYYEEMGIKPPK GVILYGAPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPS IVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSKGDVKVIMATNRIETLDPA LIRPGRIDRKIEFPLPDEKTKRRIFAIHTSRMTLAEDVNLEDYIMAKDDLSGADIKAICT EAGLLALRERRMKVTNEDFKKAKENVLYRKNEGTPEGLYLKRKPYSPFQPSNTADFALAR IDDLVNWARKSSLWPLTFGLACCAVEMMHFAAPRYDMDRFGVVFRASPRQADCIIVAGTV TNKMAPALRKIYDQMPEPRWVISMGSCANGGGYYHYSYSVVRGCDRIIPVDVYVPGCPPT AEALLYAVLQLQKKIKRMKLTQMWYRKDNFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYA NNSNYKNDTMIRKEAYVHKSVMQELKRIIEDSEIMEEDDALWPPPDRVGRQELEIVLGDR HISFTTTKIGSLIDVNQSKDPEGLRTFYYLVQDLKCLVFSLIGLHFKINPIXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMTEYKLVVVGAGGVGKSA LTIQLIQNHFVEEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGF LCVFAVNNSKSFDDINQYREQIKRVKDADEVPMVLVGNKVDLPSRSVETRQGKTKAETYG IPYIETSAKTRQGVDDAFYTLVREIRKYMGDRYNIHSQLEHLQSKYIGTGHADTNKWEWL TNQHRDSYASYMGHFDLHNFFAIAENETKARVRFNMMQRMLQPCGPPPERMEDMKIELCV FSGSKIYPGHGKKIVKVDGRTFQFVNAKCAKLHTSKRNPRKVHWTVLYRRKHKKGIQEEV QKKRTRRTVKFQRAITGATLNDILAKRNQKPEVRQAAREQAIRAAKEKAKAKDKAAPRVG GKRMKLNISYPATGCQKLIEVDDERKLRCFYEKRMAQEVSAECLGDEWKGYVVRISGGND KQGFPMKQGILTNGRVRLLLSAGHSCYRPRRDGERRRKSVRGCIVDANLSVLSLVIIK-- ------------------------------------------------------------ ------------------------------------------------------------ --KKGEDLLKQLDDLKTELSQLRVAKVTGGAASKLSKIHTVRKSIARVF---DGYQPNAK RKTYRPKGLRPKKTRAXRRALTPHELSLKTAKQ--------------------------- ----------------------VPKTVKNFKTIAIGTESYKGSKFHRVIKDFMIQGGDFT RGDGTGGKSIYFADENFKLKHYGAGWVSMANAGKDTNGSQFFITTKKTEWLDGRHVVFGV VVEGMDVVRKIENVAKDRDRPTKDVVIADCGEIPVDTPFSVPQK---------------- ------------------------------NFKSKVVLSSEIPFSKRYLKYLTKKYLKKH NLRDWLRVVASAKDSYELRYFQINNEDEEEDDDK-------DETRYGGCEGPEAMYVKLV SSDGHEFIIKREHALTSGTIKAMLSGPGQFAENETNEINFREIPSHVLQKVCMYFTYKVR YTNSSTEIPEFPIAPEIALELLMAANFLDC-----LEELRQHKDGKSLWLAIHDTVYDVT KFMDEHPGGEEVLLEQAGGFATDAFEDVGHSTDARELMKQYAIGKLAESDQSSWTQWLVP LLIAAAATFAYRYYMSYMLQHLHNGWQVDQAILSEEDRVVIIRFGHDWDPTCMVMDETLY KVAERMKNFAAIYLVDVSEVPDFNKMYELYDPCTVMFXYRNKHIMIDLGTGNNNKINWAM EDEQEFIDIVETVFRGARKGRGLVISPKDYSTKYRYKKLQKQLEFLQVQEDYIKDEQKNL KKEYLHAQEEVKRIQSVPLVIGQFLEAVDQNNGIVGSTTGSNYYVRILSTIDRELLKPSA SVALHKHSNALVDVLPPEADSSITMLSADEKPDVAYSDIGGMDIQKQEVREAVELPLTHF ELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVR DVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTVNVKVI MATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLVFATITSKMNLSEDVDLEDYVARPD KISGADINAICQEAGMQAVRENRYIVLPKDFEKGYKNNTKKDEMELEFYKSHEHYSLNEV NDRVMLVLRLYDKIDPERLSVDSHFTNDLGLDSLDHVEVIMAIEDEFGFEIPDSDSERLV RPADLIQYIADKFDVRRVVQSIPDDLKNVEFETSEDVEVTPTFDGIGLREDLLRGIYAYG FEKPSAIQQRAIKPIIKGRDVIAQAQSGTGKTATFAISVLQSLDTQVRETQALVLSPTRE LALQIQKVVLALGDYMAVQCHACIGGTNIGEDIRKLDYGQHVVSGTPGRVFDMIRRRNLR TRAIKMLILDEADEMLNKGFKEQIYDVYRYLPPATQVILVSATLPHEILEMTSKFMTDPI RILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKM REANFTVSSMHGDMQQKERESIMKEFRSGASRVLITTDVWARGIDVQQVSLVINYDLPNN RELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLIVPTRRP FDPVAHDLDVNFRLTKFSDLKGGCKLPRDGLNKMLEPLREQLEAEQAHFQYVVPSPRMGV GMDACITPIRHGGLSQVQSTSVFYVLIDDPYMMGKVAGAAVLSNLYAMGVTECDNMLMHV GVPQKMTDKERNVVLPLLTTGYKDATEDAGTSVNGGQTILNPWMFVGGVATSTCQPNEYI MPDNAMVGDVLVLTKPLGTQVAVTAYQWLDMADKWNRIKLVVSEEDVRKAYQRAMFSMAR LNRVAAILMHKYNAHGATDIGGFGLLGHANSLASIQKNEVGFVIHNLPVIAKMAAVSKAC GNMFGLLQGHAAETSGGLLIALPREQAAAFCKDIEKQEGYQSWIIGIVEKGVRTARIIDK PRVIEVPAKDKE------------------------------------------------ ------------------------------------------------VMSASDVGEKPK MELRQIREMINELSTALTGVKHEQEYMEVRERIHRAINDNTKSRVVLWSXFEALVLVAMT LGQVYYLKRFFEVRRVVMSATLQPYLKAVRHTLTAAMCLDNFSSQVVERHNKPEVEVRTS RELLLTPVVISRNEKEKVLIEGSVNSLRISIAIKQADEIEKILCHKFMRF---------- ------------------------------------------------------------ -----SRKKTLLKVIILGDSGVGKTSLMNQFVNRKFSNQYKATIGADFLTKEVFVDNRLV TLQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTVANTFKTLESWRDEFLIQASPQDPNH FPFVVIGNKIDLDNRAVTAKRAQQWCTAKGNIPYFETSAKE-----------ARKALAQD SMSEQYNEFPDQIRLS----------TTPFDARFPNQNQTRNCWQNYVDYHRCQKIQDYQ PCEYFSQAFRSLCPNEWVNTWDEQREKGSFAGKIMPDYLGSDQRKTKED-EEDKPIQSLD EGDIALLKTYGAGMYHTTIKKTEDDIQSIMKRVNELTGIKESDTGLAPPAHWDLAADKQT LQSEQPLQVARCTKIINADSDDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNK YQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVEVPLLHPEKFVNLGI DPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMART KKACIVFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDT LDPALTRPGRLDRKVEFGLPDLEGRSHIFKIHARSMSVEKDIRYELLARLCPNSTGAEIR SVCTEAGMFAIRARRKMATEKDFLEAVNKVIKAYAKFSATPRYMTYN------------- ------------------------------------------------------------ --------------------------------------AVLVVAAGVGEFEAGISKNGQT REHALLAFTLGVKQLIVGVNKMDSTEPPYSEARYTEIQKEVSAYIKKIGYNPDAVPFVPI SGWHGDNMLKMGWFKGWKVVSGTTIMEALDNIEPPKRPTDRPLRLPLQDVYKIGGIGTVP VGRVETGTIKAGMVVTFAPVNVTTEVKSVEMHHQALEEASPGDNVGFNVKNVSVKDIRRG NVAGDSKNDPPKESEEFKAQVIILNHPGQINAGYAPVVDCHTSHIACKFRDLLEKIDRRS GKKLEDNPQNVKSGDAAIVEMVPQKPMCVEAFSDYAPLGRFAVRDMRQTVAVGVIKSVKK KEGGQAKVTKSAQKA--------------------------------------------- ------------------------------------------------------------ -------------------------------------------FLDDNQIVTSSGDMTCA LWDXETGQQTTSFTGHTGDVMSLSVAPDFRTFVSGACDASAKLWDIRDGMCKQTFSGHES DINAITFFPSGYAFATGSDDATCLLFDIRADQQIGMFSHDNIICGITSVSFSKSGRLLFG GYDDFNCNVWDTLKQERAG----------------------------------MSYSYLF KYIIIGDTAVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQES FRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLDDARQHSSSNMVIMLIGNKSDLEARR DVKREEGEAFAREHGLIFMETSAKTAANVEEAFINTAKEIYQKIQ--------------- ----------------------RGVIELGDVTVHNVKQLKKLNQAIFPVVYNDKFYKDVL QFGELVKLVYFNDVIVGAVCSRDEKTDGQKRLYIMTLGCLAPYRRLGIGTAMLKHLLDYC QKDGSYDNVYLHVQVSNSDAIAFYEKFGFSIVERKENYYKRIEPADAFVVQKDLK-MPRQ IMDIKDFLLTARRQDAKSVKIKKNVKFKVRCSRYLYTLVISDKEKAEKLRQSLPPGLQVK ELKMSKISRESLLEAVNGMLQKKRKFTETVELQVALKNYDPQKDKRFSGTVKLRYIPRPK MSVCVLGDQQHCDEAKANEVPHMDAEALKKLNKNKKLIKKLAKKYDAFLASDSLIKQIPR IVGPGLNKAGKFPTALSHSESMVGKIDEVKATIKFQMKKVLCLAVAVGHVNMPPEELAAN INLAINFLVSLLKKNWQNVRSLYIKSTMGPALRLYMADADKLNIDSIIARLLEVRGSRPG KNVQLSENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT LFSAPNYCGEFDNAGAMMSVDDTLMCSFQILKPADKKKFQASGNQTGRPVTPMRGNPKSG GKMMFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHLKRITDSDIQSLVLEIAGTNVSTT YITCPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPF ICTMPMRLDEGWNQIQFNLSDFTRRAYGTNYVETLRVQIHANCRVRRVYFSDRLYSEEEL PAEFKLYLPVQARMTDSGIQNLQDPFAEDE-IHIRIQQRNGRKTLTTVQGVSSEFDLKKI VKVAKKEFACNGTVVEHPEYGEVIQLQGDQRQNMSKFLKQVGLEDQIKVHGFSALFNFQS LLTVVLLLICTCAYIRSIMPSLLDRNKQGLLGIFWKCARIGERLSPYVSFCCVAMAFSIL FL-TGRIATFAVRQLPKSLAEKQALGAGFVATRKLTLSAEISSILEERILGSTTANLEET GRVLSIGDGIARVYGLKNIQAEEMVEFSSGLKGMALNLEPDNVGIVVFGNDKLIKEGDIV KRTGAIVDVPVGLELLGRVVDALGNPIDGKGPIK-ASRARVGVKAPGIIPRISVREPMQT GIKAVDSLVPIGRGQRELIIGDRQTGKTAVAIDTIINQKRFNEGQNEKAKLYCIYVAIGQ KRSTVAQIVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCAMGEFFRDNGRHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDTFGGGSLTALPVIE TQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQMRAMKQVAG SMKLELAQYREVAAFAQFGSDLDAATQQLLSRGVRLTELLKQGQYAPMAVEEQVAVIFAG VRGFLDKVDPSRITTFEREYLAHLRSSQQDLLKSIREAGKLTDETEAKLKQVVTNFLSGF MEAMYAAPYHLLECPNLKLKRPSWVHTPSAMVVFAVVLMSYFLVTGGIIYDVIVEPPSIG STT--------------------------------IGGLGFVILDQTNKPTTPRLNRILL LSIAFVSILVSFFMCRIFMRMKLPMPKVKRTRKPPPDGWELIEPTLDELDGKMREAETDP HEGKRKVEALWPIFRIHHQKSRYIFDLFYKRRAISRELYEYCLKENIADKNLIAKWKKPG YENLCCLRCIQTKDTNFGLNCICRVPKTKLEEGKIVECINCGCRGCSGEYAQVTKMLGNG RLEAMCFDGTKRLCHIRGKLRKKVWINTGDIILIGLRDYQDTKADVILKYSSDEARNLKA YGELPESAKINEEDMDDITFDDIDDI---FLMKLSHESVTIELKNGTQVSGAIQGVDVAM NIHLRSVKMTVRGREQISLDTLSIRGNNIRYIVLPDSLPLDTLLIDDEPRKKPTQTTVAK PKSEMTAEELAQKEQEEFNTGPLSVLTQSVKNNTQVLINCRNNKKLLGRVKAFDRHCNMV LENVKEMWTEVPKTGKGKKKSKPVNKDRYISKMFLRGDSVILVLRNPLPIVIDARGHLLG RLAAIVAKTTLQGQRVVIVRCEGINISGNFYRNKLKYLDFLRKRMNTNPSRGPYHFRAPS KIFWRTVRGMLPHKLTRGKEALERLKVYEGVPAPYDKMKRLVVPSALRVLRLKPRRKYCA LNRLSHEVGWKYQTVVATLEKRRKLKSSVFHKRKV------------------------G GDAEKGKKVFVQRCAQCHTAEAGGKNLQGPNLHGVVGRKTGQVPGFSYTEANKNRGITWS RDTLFEYLENPKKYIPGTKMVFAGLKKESERLDLIAYLESQSKIFVERTLAMIKPDAVSK EIEDVILRSGFTILHKRRVHLSPEQASEFYAEHFGKLFFQXLVGFMSSGPIVALVLAREK AITSWRELIGPTNSLKARATQPESLRAIFGTDDQRNALHGSDSYSSAEREIRFFFPETVL EPVAVGQPAKDYLMEAVNPTLLKGLTELCKQKPLQPVIWLADWLIQNNPNKPAI-MFEAR LVQGSLFKKVLEAIKDLLNEATWDCNSTGMSLQAMDSSHVSLVSLSLRSDGFDTYRCDRN ISMGINLASMSKILKCAGNDDAITVKASDNADTITFMFESPNGEKVSDYEMKLMDLDTEH LGIPETDYSCVIKLPSAEFQRICRDLSQIGESVVICCTKEGVKFSANGDLGTGNIKLAQS SNVDKEDEAVTIEMQEPVVLTFALRYLNFFTKATPLSSQVCLSMSADVPLVVEYKIGDMG FIRYYLAPKIEDGEDAKSAAAFHTTRHGAQGRIVAVIGAVVDVQFDDHLPPILNALEVSD RKPRLILEVAQHLGENTCRTIAMDGTEGLIRGQVCTDVGSPIRIPVGPETLGRIINVIGE PIDERGPVNAKSFAEIHADAPEFVEMSIEQEILETGLKVVDLLAPYAKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIMSGVIDLKGDKSKVALVYG QMNEPPGARARVALTGLTVAEYFRDKEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTQKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIA ELGIYPAVDPLDSTSRILDPNVVGQEHYEVARGVQKILQDYKSLQDIIAILGMDELSEDD KLTVARARKIQRFLSQPFQVAEVFTGTEGKLVPLKDTIKGFKMILNGELDHLPEIAFYMV GPIEEVVKKAERLAEERMLMPVKNRHTIYEYLFKEGVLVAKKDFQAPKHPEIDVPNLQVI KTLQSLKSRGYVKEQFAWRHYYWYLTNEGIQFLRDALHLPPEIVPATLKRQQGGEDRAAY RREGGADKKAEAGAGATMGKQNSKLKPEQLEDLRANTMFSDEEIQEWYKGFLKDCPSGHL TVDEFKKIYGNFFPYGDASKFAEHVFRTFDKNGDGTIDFREFICALSVTSRGKLEQKLKW AFSMYDLDGNGYISRQEMLEIVTAIYKMVGTVMKMPDDESTPEKRTDKIFRQMDKNLDGR LSLEEFIEGAKSDPSIVRLLQCEPMSSSEEVSWISWFCGLRGNEFFCEVDEEYIQDKFNL TGLNEQVPHYRQAIDMILDLEPDDDLEDNPNQSDLIEQAAELLYGLIHARYIMTNRGIAQ MIEKWQQGEFGTCPRVYCDNQPTLPIGLSDVPGEAMVKLYCPKCQDVYVPKSSRHHHTDG AYFGTGFPHMLFMVHPEYRPKLPTNQFTPRLYGFKIHPLAYELQYQAAANFKATYTNNNK MTNSKGYRRGTRHLFSRKFRKHGLIPLSTYMKVYKKGDRVDIKGNGAVQKGMPHKSYHGR TGVVYNVTQHAVGVIVNKRVKGRILAKRINVRVEHVKHSRCRQDFLDRVAENERKKKEAK EIVHCKRQPAQPHPGHFVRTKYNKPVVLEPIPYEFIASSRMHWKQVSP-EVGMEWSDMTD RAANKAFLLEVFKGLGIVTSQWFKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAICPAQAITIEAEERADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEY ITETREELFYNKEKLLQNGDRWEVEIAANLQADHLYR------------------DKGQQ EAIEQIDEVQNEIDRLNEQASDEILKVEQKYNKLRQPHFHKRSELIAKIPNFWVTAFVNH PQVSALLNEEDEEVLQYLTRVEVQEFEDIKSGYRINFHFEENEYFENKVISKEFHLNSSK STPINWKPGKDLTKQPKKRTHQDQESFFSWFLDHTDAGADELGEVIKDDIWPNPLQYYLA SEIEEGGS-EDGNPEDDKKLTKQEELLLQDFSRNVSTKSSALFYGNAFIVSAIPIWLFWR IYQMDLYLLYVAMTLATAYFIALAYKNVKFVLKHKVALKRADAVSKEMMKKFADDKKMSK QEKEERILWKKNEVADYEATTFSIFYNNALFLTLIIIASFYVLRSFSPSVNYVLSMASAG GLLWLFSTSTKTQPSRVCQFKVVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQT ICIDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIIVYDITSQETFVRAKSWVKELQRQ ASANIVIALAGNKADLRVVEFEEAQLYADENSLLFMETSAKTAVNVNEIFLAIAKKLPKN EPGVDLSRGGMAEYLASIFGTEKDKVNCSFFFKIGACRHGERCSRLHNKPTFSQTILLQN LYLNPQNSAQIGVSDTELQEHYDGFFEEVFSELEEKYGRIEEMNVCDNLGDHLVGNVYVK FEREEDAERAVNELNNRWFNGRPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKP ISRELRRRLYGRSKRSRSRSPPTRRSRSRSR----GRYGGRDR--MFLTRSEYDRGVNTF SPEGRLFQVEYAIEAIKLGSTAIGVQTQEGVVLAVEKRVTSPLIVASSIEKILEIDTHIG CAMSGLIADSRTLIDKARIEAQNHWFTYNERMRVESVTQAVSNLALQFGDDDADPGAMSR PFGVALLFAGVDNDGPQLFHMDPSGTFLQYDAKAIGSGSEGAQQSLQEVYHKSMKLDEAC IEALKILKQVMEEKLTSTNIEMATVTRDKLFHMLSKDEMEAFISKLAQKTWEMSNSMEVV GSVDEIYHYNKQQQQDILSAKPWEKDPHYFSCIKISALSLLKMVMHARSGGNLEVMGLLV GKVDGNNMIVMDSFALPVEGTETRVNAQAQAYEYMAAYMEAAKQVGRLENAIGWYHSHPG YGCWLSGIDVGTQMLNQQFQEPFVAIVIDPIRTISAGKVNLGAFRTYPKGYKPPDESSSE YQSIPLNKIEDFGVHCKQYYALDVSYFKSSLDRRLLEMLWNKYWVNTLSSSSLLTNADYM TAQIYDLTDKLEQSENHLGRGSFVPEKTEDKLTKATKDSCKNVMESIHGLMSQVIKDRLF NQI-GLPKRILKETQRLKAEPVPGIEATPDESNARYFHVIVVGPRDSPYEGGVFKLELFL PEEYPMSAPKVRFMTKIYHPNIDKLGRICLDILKEKWSPALQIRTVLLSIQALLSAPNPD DPLANDVAEQWKVNEAQAIETARQWTRKYA-----------------KDVKGTYVSIHSS GFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVVCQAKSGMGKTAVFVLATLQ QLEPVAGQVSVLVMCHTRELAFQISKEYERFSKYMNSVKIAVFFGGMVITKDEQTLKSNC PHIVVGTPGRILALVKALNLKHLKHFILDECDKMLEQLDMRRDIQEIFRATPHEKQVMMF SATLSKDIRPVCKKFMQDPMEVYVDDDSKLTLHGLQQHYCKLKDNEKNRKLFDLLDALEF NQVIIFVKSIQRCMALTQLLVEQNFPAIAIHRAMPQDERLSRYQQFKDFQKRILVATNLF GRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDESDAKV-------- -----------------------TQNGIEFTVNGNSNHDTKKFNGSLETKYKWSEYGITF NEKWNTDNALATEITVEDQLLKGLKLSFDTLFVPQTGKKSGKIKTEYKHEFVHTNVDVDF NFAGPTIYGAAVVGYKGWLAGYQLALDKSLLSQSNFAIGYSKDDLTLHTAVKDNSEFSGS VYHKLTGKLETGVLVDWTVGSNDTRFALGAKYSPDKETTLRAKLNNASQIALSYQQKLRD GVTLTLSTQLEGKNFSQGGHKFGLGVDFEAVNVREKILQDFRKKLMEHKELESRLKEMRE QLKELTKQYDKSENDLKALQSVGQIVGEVLKQLTEDKFIVKATNGPRYVVGCRRQLDKTK LKAGTRVALDMTTLTIMRYLPREVDPLVYNMSAEDPGDISYAQIGGLGEQIRELREVIEL PLMNPELFQRVGITPPKGCLLYGPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIGES ARLIREMFCYARDHQPCIIFMDEIDAIRRFSEGTSADREIQRTLMELLNQMDGFDALGQV KMIMATNRPDTLDPALLRPGRLDRKIEIPLPNEQARMEILKIHASPIAKHGEIDWEAVVK LSDDFNGADLRNVCTEAGMFAIRAERDYVIEEDFLKAVRKIADNKKLESKLDYKPVMPES VKSIVQHFYDGYVQNTPKKLKIIDVYLLYILITGVVQFVYCCLVGTFPFNSFLSGFISCV GSFVLAVCLRVQVNDQNK--FSGISPERAFADFVFAHIVLHLVVINFIGSLSSPTQLLPL EIVDKCIGSKIHIIMKNDKEIVGTLLGFDDFVNMVLEEVTEFESTLEGRRVTRLDRILLN GNNITMLVPGGEGPEVIDHYENPRNVGALDKNDKSVGTGLVGAPACGDVMKLQIKVDENG KIIDAKFKTFGCGSAIASSSLATEWVKGKTLKEASSITNSQIAKELCLPPVKLHCSMLAQ DAIKAALNDYQKKN--------------------------------------------ES VDYLKTLASDVHVVRGDFDENLNYPEQKVVSVGQFRIGLCHGHQVVPWGDIESLAMVQRQ LDVDVLISGHTHKFDAFEHEDKFYINPGSITGAYSALDSNIIPSFVL------------- ------------------------------------------------------------ ------------------------------------------------------------ LRRKARRDVKAKFEERYKTGKNRWFFQKLRFERSFIMIKPDGVHRGVVGEIIKRFEQKGY KLVAMKLVWASEELLKQHYDDLKEKPFFPGLVKYMSSGPVVPMVWEGKVVEIGRVILGAT DPLKSNPGTIRGDFGIDVGRNICHGSDSVDSANREIKLWFKDEELVSWTPAETDWVYETG VPKPVKTPAKARDKAQKSKKAVLHGVHDKRVRKVRTSVHFRRPKTLMLPRAPKYPQKSTT KRVRLDQFKIVKFPLTTESAMKKIEDNNTLVFIVDKRANKPQIKMAVHKLYNIQVSKVNT LIRPDGEKKAYVRLAPDYDALDVANKIGIIMAPKQKMRLANEKHSKNVLNRGNVPKSLKQ EDEKLPVGPWLLGLFIFVVCGSAIFQLIQSIRMVKFKGLTAVAIWRWVANDDNCGICRMP FDGCCPDCRLPGDDCPLVWGQCSHCFHIHCIVKWLNSQQVNQLCPMCRQEWKFKEMIRFI LIQNRAGKTRLAKWYMHFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIVYRRYAGL YFCICVDITDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYSVVDEMFLAGEIRE TSQTKVLKQLLMLSSLEKPTIFSRIIDRSVPAKIIYEDEQCIAIHDINPQAPVHFLVVPK KVVLGIAEDQQLLGHLLLVAKIVAEKESGYRLVINNGPDGCQSVYHLHLHVLGGRQMRWP PMGGLISYFSSLFGSRERRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVQYKN LKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSMDRDRIGISKQELVSMLEEEELKKSV LCVFANKQDIEGAMTVTEVANALGLSAIKNRRYQIFKTSAIKGDGLDEAMEWLANTLQSS KGLYFHIGETERKCFIEDIPDETMVVGKYKVEVFDKTQHQYVPTTGGLGMHVEVRDPDDK TIMSRMYAMEGRFTFTSASAGEHIICIHSNSTSWFSSGQLRVHLSIQVGENANDYQEIAA RDKLSELQLRIRQLLDQVEQISKEQNYQRYREERFRETSESTNQRVLWWAIAQTVILVVT GLWQMKHLKGFFEAKKLVMFYHVSLTHDILLHPRYFGPNLLNTVKQKLFTEVEGTCTGKY GFVIAVTTIDNIGDGLIQPGRGFVVYPVKYKAIVFRPFKGEVLDAVVTQVNKVGLFTEIG PLSCFISRHSIPADMEFDPNSNPPCYKTKDEETVIQTEDEIRVKIVGTRVDATDIFAIGT LMDDFLGLVSRLYVKAVFTGYKRGHRSQHENTSLLKLDGVNDKSDASFYLGKRAVYMYKG HKTIARGGGPK-TRVRAIWGRITRVHGNSGVVRAKFRHNLPPTAMGKRIRVMLY---KQW DLLVRLLMIGDSGVGKTCLICRFCDDTFDSRH-STVGIDFKMKSVLMNGKKVRIQVWDTA GQEKYDTITQQYYRRAQGICLVYDIXNVDSFKNLKKWIRQVKDFAADDVEMILVANKSDM EDSRKVKPGKGKQLAKQLKIPYFETSAKDSENIEQAFLLLADSVIRKMPQNEYIELHRKR HGRRFDYEEKKRKREGRQPHEASQKAKKLRGIKAKLHNKKRHSEKIQMKKTIKMHEQRNT RQKVPENRLDHPVPKYILDREEQTRAKVLSNTIKQKRKEKAGKWDVPLPKVRGVSEAEVF KVVTTGKSRRKAWKRMVTKVTFVGEGFTRKPPKYERFIRPMGLRFKKAHVVHPDLKATFC LPIIGVKXNPTSPLYTSLGVITKGTIIEVNISELGLVTQGGKVIWGKYAQVTNNPENEGC INAVLLVVASRPLVTVYDEKGESTGQNVPTPAVMLAPIRPDVVSFVHMEMLKNGRQPYAV SVKAGHQTSAESWGTGRAVARIPRVSGGGTNRSGQGAFGNMCRGGRMFAPTKTWRRWHRR ININQRRYALCSALAASAIPSLVLSKGHRIEQIPEVPLVLSDKVQELKKTKEAVAVLHKL KVWPDIEKVKNSRRFRAGIGKMRNRRRIQRRGPIIIYSQDNGICRAFRNIPGITLINVDR LNLLKLAPGGHVGRFCIWTESAFKKLDSIYGTWAVASKAKVHYNLPMPKMSTTDLQRLLK SDEIQKALRPPKKEIKKRVLKRNPLKNLAVMQRLNPFAVTQKKIAKHKKLRQQKIDARRG IVTVDSGSKARPHKSVKGNDEEELASKTLMIQSKRFYIDVKQNQRGRFIKIAEVGPGGKK NRLLLPMSTAAELRDCLTNFSEHYASLGPASSDSQREDGVLKSDMLQKDNRRYFLDLKEN KRGRFLRVSPMSRVRPQVVIPAQGMIEIRDTLTDLLNEFGTDDHASTELLPEPQSLRVDN KMFYFDVAQNRRGTFMRISEPTVRTAITVPQHSWKKFRDIISEFVER--ERSRDVQLRAT INQKLIETGERERLKELLRTRLIECGWRDELKQCCKEIVRTKGLE--------------- -------------------------MNIRNAKPEDLMNMQHCNLLCLPENYQMKYYFYHG LSWPQLSYVAEDDKGKIVGYVLAKMEEDPEDSVPHGHITSLAVKRSYRRLGLAQKLMDQA SRAMVECFGAKYVSLHVRKSNRAALHLYSVTLKFQVSEVEAKYYADGEDAYAMRRDLSEF WEKYMAHTILLVQPGKKPEGRTYSDYETVNECLEGVCKIYEEYLKKMNPNSPSITYDISQ LFEFIDQLADLSCLVYDKTTHQYAPRNKLWIKEKXFVMLRQQAGKMAEEG-EKKEAESKK --HTYPLIRHSDMPEEIRVETMELCVTACEKFANNNETAAKMIKDSMDKKFGPAWHVIVG EGYGFEITHETKNLLYMFFGGNVAIVVWKCS----------------------------- ------------------------------------------------------------ ----------------FAEHLSDECRRRFYKNWYRSKKKAFTKAATKWQDELGKKVIEKD FAKMKKYCSIIRVIAHTQMKLMNRRQKKAHIMEIQLNGGTIADKINWAREHLEKAIPVTQ VFAADEMIDVIGVTKGKGFKGVTSRWHTRKLQRKTHKGLRKVACIGAWHPSRVAFSVARA GQKGYHHRTEMNKKIYRIGQGIHTKDGKVIKNNASTDHDITEKAITPMGGFPHYGEVKQD FIMLRGCCMGPKKRVITLRKSLLVQTSRRALEKVNLKFIDTSSKFGHGRFQTHEEKGTFM GTLKKDMQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGRPINLG LWDTAGQEDYDRLRPLSYPQTDVFLICFSLISPASFENVRAKWFPEVSHHCPSTPIVLVG TKLDLREDKETIDRLRDKKLSPITYPQGLAMAKEIGAVKYLECSALTQKGLKTVFDEAIR AVLCPKPKPKKKKACKILVFDPSLKKKKKKKTSFDPEAFGQDINLDD-ALIKKKKKKKAF DMSEVGSALPQVDATSAKKKKKDDSDRDYTYDELLKRVFDIMREKNPDMVAGEKKRFVMK PPQVMRVGTKKSSFSNFAEICKMLHRQPKHLLAFLLAELGTSGSIDGNNQLIIKGRFQQK QIESVLRRYIKEYVTCHTCRSPETILQKDTRLYFLQCETCGSRCSVASIKSGFQAVTSKR AAIRAKT-FDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDITRPEGK DYSLHRLILGTHTSDEQNHLLIASIQLPNDNAQFDVSHHDTEKGEFGGFGSVSGKIEIEI KINHEGEVNRARYMPQNPCVIATKTPSSDVLVFDYTKHPSKPDPSGECRPDLRLKGHQKE GYGLSWNPNVNGHLLSASDDHTICLWDINATPREGRVINAMTIFTGHTSVVEDVSWHLLH ESVFGSVSDDQKLMIWDTRCTNSSKPSHTVDAHTAEINCLSFNPYSEFILATGSADKTVA LWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEDQSAEDA EDGPPELLFIHGGHTAKISDFSWNQNEPWVICSVSEDNIMQVWQMAENIYNDEEPDVANA ELEMPVPSRARVYADVNTHRSREYWDYESHIVTWGQQDDYQCVRKLGRGKYSEVFEAINI TNNEKCVIKILKPVKKKKIKREIKILENLRNGTNIINLLAIVKDPVSRTPALIFEYVNNT DFKQLYQTFTDYDIRYYILEVLKALEYCHSQGIMHRDVKPHNVMIDHENRKLRLIDWGLA EFYHPGQEYNVRVASRYFKGPELLLDYQLYDYSLDLWSLGCMFASMIFKKEPFFHGHDNY DQLVRIAKVLGTEELFEYIDKYQIELDPRFNDILGRHSRKRWERFVHSENEHLVSPEALD FLDKLLRYDHQDRLTAREAMDHPYF----------------------------------- ------------------------------------------------------------ ---------------------------GYPNLKTVRELIYKRGFAKVNGSRIPITDNSII ESKLGKYGIICIEDLIHEIYTAGPHFKQATNFLWYFKLNTPNGGWRKKSNHFVDGGDFGC REDKINTLLRKMMQFMLLFSRQGKLRLQKWYVATXDKMKKKXTRELITMVLSKKXKMCSF IEWKDMKIVYKRYASLYFCCCVEASDNELLTLEIIHRYVELLDKYFGSVCELDIIFNFEK AYFMLDELLLGGEVQESSKK---------------------------MSKAHPPELKKYM DKKMSLRLNGSRIVTGILRGFDPFMNLVIDEAVEECKTGEKNPIGMVVIRGNSVGLLEAL ERV--------------------------RFMYDSFDNTYQATIGIDFLSKTMYLEDRTI RLQLWDTAGQERFRSLIPSYIRDSSVAIVVYDITNANSFQQTSKWIDDVRTERGSDVLIM LVGNKTDLSDKRQVSTEEGEKKAKDLSVMFIETSAKAGYNVKQLFRRVAASLPGMDQAEQ KP-IKLESKQPPIELHKMAIIYDMAVGLKKGHKVTTRKPRPSRRKGALTKHAKFIRDLVK EVCGFAPYEKRAMELLKISKDKRALKFCKKKLGTHLRGKRKREEMSATIQKMRKAMVDEA TKRQLASIPLLKTNAGPRDGDLWVQRLKEEYQSLIKYVENNKQSDSDWFRLESNREGTRW FGKCWYIHDLIKYEFDVEFDIPVLYPTTAPEIAIPELDGKTAKMYRGGKICMTDHFKPLW AKNVPKFGIGHAMALGLGPWLAVEVPDLVSKGLVKPKEFLDSLGFLDELRRMNARQLYYQ FLNFAMIVSSALMIWKGLMVVTSSESPIVVVLSGSMEPAFYRGDLLFLTNHEEEPIRVGE IVVFKIEGREIPIVHRVLRVHEKENGTMKFLTKGDNNQVDDRGLYAPGQLWLEKKDVVGR AKGYVPYVGIVTILMNDYPKFKYITLALLGAFVLIHREMSAMNPEYDYLFKLLLIGDSGV GKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYR GAHGIIIVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKSDLTTKKVVDYTTAKEY ADQLRIPFLETSAKNATNVEQAFVTMAAEIKNRMGPSATAPNVKINASTPVKQGGGGCCQ ESLAEEVLRMSNDEIVSRTRLLDNEIKIMRSEVLRISHELQAQKEKIKENTEKIKVNKTL PYLVSNVIELLDVDPQDQAEEEGANVDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEQL KPGDLVGVNKDSYLILETLPQEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELIEAVVLP MTHKDRFKSLGIQPPKGVLLYGPPGTGKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGA KLVRDAFALAKEKAPAIIFIDELDAIGTXRFDSEKAGDREVQRTMLELLNQLDGFHPNHD IKVIAATNRVDILDPALLRSGRLDRKIEFPAPNEEARARIMQIHSRKMNVSKDVNFEELA RCTDDFNGAQCKAVCVEAGMIALRRSATELSHEDYMDAILEVQAKKK-------RDAADQ SFDYMFKLLIIGNSSVGKTSFLFRYADNSFTSAFVSTVGIDFKVKTVFRQDKRVKLQIWD TAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWSTQVKTYSWDNAQVVLVGNKS DLDDERVVSTERGRQLAAQMGLEFFETSAKDNVNVKAVFERLVDIICDKMSESLDTE--- -----------------SRVHQAAVSRDYISQPRLTYKTVSGVNGPLVILDGVKFPKFAE IVKLTLHDGTVRSGQVLEVSGSKAVVQVFEGTSGIDAKHTSCEFTGDIMRIPVSEDMLGR VFNGSGKPVDKGPSVLAEDYLDIQGQPINPWSRIYPEEMIQTGISAIDGMNSIARGQKIP IFSANGLPHNEIAAQICRQGGLVKVPGKAVHDTSADNFAIVFAAMGVNMETARFFKQDFE ENGSMENVCLFLNLANDPTIERIITPRIALTTAEFLAYQCEKHVLVIMTDMSSYAEALRE VSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLT GYITEGQIYVDRQLHNRQVYPPINVLPSLSRLMKSAIGEGMTRDDHADVSNQLYACYAIG KDVQAMKAVVGEEALTPDDLLYLEFLGKFEKNFIAQGPYENRTIFETLDIGWQLLRIFPK EMLKRIPQKTLAQYYPREG-GLAFVGIKFCQECNNMLYPKEDKDSRKLLYACRNCDYQQE ADNPCIYVNKIQHDVDEMTQIIGDVIADPTLPRTEDHPCNKCGHKEAVFFQSQTRRAQEG MRLYYVCTNPNCLHRWNEKLPYKVADINLAEWGRKTIEIAEKEMPGLMMVRKVYGPSKPL AGARIAGCLHMTVQTAVLIETLTALGAEVQWSSCNIFSTQDHAAAAIAKTGVPVYAWKGE TDEEYVWCIDQTLIFRDGQPLNMILDDGGDLTNLVHEKYPHLLAGIRGLSEETTTGVHNL YKMLQKGELKVTAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGKVAFVGGYGDV GKGCASSLRGFGARVLVSEVDPINALQAAMEGYEVTTIEEAVKSARIFVTATGCKDIIRG EHFAQMLDDSIVCNIGHFDCEVDVKWLNTNCKSKDTIKPQVDRYTLQNGRHIILLAEGRL VNLGCAMGHPSFVMSNSFTNQVLAQIELWTKPEKYPLGVHFLPKSLDEEVARLHLDHLGV KMTKLSADQASYLGVGENGPFKPDHYRYAEEAADQVVNAVEEPLDLIRLSLDERIYVKMR NDRELRGRLHAYDQHLNMILGDVEETVTTVVIDDETYEEIYKSTKRTI------------ -------MSTSNVENVSPQIIRQVTKELMELQKDPLEGVKVYLNEEDITDIHATIEGPDG TPYAGGHFRVKLVLGKSFPAEPPKGFFLTKIFHPNVAKNGEICVNTLKKDWKADYGVKHI LLTIKCLLIYPNPESALNEEAGKLLLEHYDDYSARARMFTEIHACPMSRTISDLVRNSPF AGPFGLKINEHREVAALGPGDSCAYGSGKYYALCGLGGILSCGLTHTAVVPLDLVKCRIQ VDPAKYGGIVQGFKVSMAESGVRELGKGWAPTFFGYSAQGLCKFGFYEVFKHVYADLVGE ETAYLWRTTLYLAASASAEFFADIALCPMEAVKVRIQTKPGFARTLREGFPKILQEEGAW GFYKGIVPLWGRQIPYTMMKFACFERTVEALYKHVVPKPRSECSKSEQLLVTFVAGYIAG VFCAIVSHPADTIVSKLNQQKGSSFVAIGKSLGFAGMWKGLTPRIIMIGTLTALQWFIYD SVKVYFRLPRPPPPEMPESLKRKLEHWKNERYVAIALLPIIPAALAFVLDTALSAMVLHT HWRLSGVVQDYIHLSISAFGSLCYFNYTDIGFAKAVHLVYSQLNEQQEEDASELIFPKEF ENAETLLISEVQRKQQNESAEEEQELSSVFIKTLNYTQRFSKYKNRETISAVRSLLVQKK LHKFELAALANLCPETSEEAKALIPSLEGRFEDEELQQVLDDIKTQRSFQY--QSQLAKQ DLATLNIKELTPLTPAVISRQATINIGTIGHVAHGKSTLVKAISGVQTVRFKNELERNIT IKLGYANAKIYKCDDPAVQRPQCYTSRGSSHADEFPCEYSNKQKYKLIRHVSFVDCPGHD ILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILIMQNKIDLVKESQ AKEQHDQITKFVQGTIAEGAPIIPISAQLKYNIDAVCEYIVKKIPVPIRDFTSEPRLIVI RSFDVNKPGCEVDDLKGGVAGGSILRGVLKVGQEIEVRPGIVSKDTEGKLTCKPIFSRIM SLFAEQNDLQYAVPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIYIELEISYFLLR RLLGVRTEGDKKGAKVQKLAKNEVLMVNIGSLSSGGRVVAVKADLAKIGLTSPVCTEVGE KIALSRRVEKHWRLIGWGQIRRGVTVSPMAELLLDSAIRIWVFLPIVVITFLVGIIRHYV TILLSSEKKVELQQIADGQAMVRSSLLRQNGRFLPKASFQMRKHFFNNEQTGFFMKNPMT DPSMMTDMLKGNLTNVLPMIIIGGWINWAFSGFLTTKVPFPLTLRFKPMLQRGVELASLD ASWVSSASWYFLNVFGLRSMYSLILGQDNAADQSRIMQEQMTGPAMGM-PDPSKAFKAEW EALEICDHSWALENIEDELIMFLWDWFASVLNFLGLYKKSGKLVFLGLDNAGKTTLLHML KDARMAQHVPTLHPTSEELTMGGMRFTTYDLGGHHQARRVWKDYFPAVDGIVFLIDAFER ERFAESKIELHSLINDEQIASAPILVLGNKIDIPGAASEDEIRHYFGLHGLTTGKGTVAR SELRPLELFMCSVLKRQGYGEGFRWLAQYIN--------TKAEEWCRLADESFEEMDSTL AVQQFIQQAIRRDFTNIDEILTPPEGQDEGVWKYEHLRQFCMELNGLAVKLQPECNPETC TQMTATEQWIFLCAAHK------------------------------------------- ---------------------------------------------------------MPN IKLQSSDGEIFDVDVEIAKQSVMIKTMLEDDEGEEEPVPLPNVNAAILKKVIQWCTYHKD DPPPPEDDENKEKRTDDICSWDTEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMI KGKTPEEIRKTFNIKNDFTPAEEEQVRKENEWCEEK---LSKGGKKGGKKKVTDPFSRKD WYDVKAPSMFNTRNIGKTIVTRTIGAKIASDALKGRVFEVSLADLQNDEVAFRKFKLISE EVQGRNVLTNFHGMDMTTDKLRSMVKKWQTMIEAHVDVKTTDGYLLRLFCIGFTTRRQNQ IKKTAYAQTTQVRTIRRKMVELMTKEVSTSDLKEVVNKLIPDSIGKDIEKVCQSIYPLHD VYVRKVKILKKPKFDLGKLLEMHGEGSSSKPGEVGEKVDRPDNYEPPVLSSV-------- ------------------------------------------------------------ ------------FQFLHKCVQVFSEYFKELEEESIRDNFVVIYELLDELMDFGYPQVTDS KILQEYITQEGHKLEIAPKPPMAVTNAVSWRSEGLKYRKNEVFLDVVESVNLLVSASGNV LRSEIVGAIKMRVYLSGMPELRLGLNDKVLFESTGRGKSKSVELEDVKFHQCVRLSRFDN DRTISFIPPDGEFELMSYRLNTHVKPLIWVEXVIERHAHSRVEYMIKXKSQFKRRSTAN- ------------------------------------------------------------ ------------------------------------------------------MGILEK ISEIEAEMARTQKNKATMGHLGLLKARLAKLRRELIEPKGGSGGTGEGFDVAKTGDARIG FVGFPSVGKSTLLTNLAGVYSEVAAYEFTTLTTVPGCIKYKGAKIQLLDLPGIIEGAKDG KGRGKQVIAVARTCGLIFMVLDVLKPLQHKQILEHELEGFGLRLNKAPPNITFRRKDKGG INLTATVAQSELDIDTVKSILGEYRISNADITLRHDATTEELIDVIEGNRVYIPCIYVLN KIDQISIEELDIIYKIPHCVPISAHHKWNFDDLLDKMWQYLSLIRLYTKPKGQLPDYNSP VVLKADHCSVEDFCNKIHRNIMKEFKYALVWGSSVKHQPQKVGKDHVLNDEDVIQIVKRM AKHHPDLIFCRKQPGVAIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGSYQGRCVIC GGPGVSDAYYCKECTITEKDRDGCPKIVNLGSAKTDLFYERKKYGFKKRPNLPPLSGSQL TGKTEVRRIPVPSHRYAPLKEKWMSIYTPVVEQLHLQIRFELKSRNVEIKTCKDTTDVGA LQRAADFVRAFTLGFEVEDALALLRLDHLYLESFDITDVKPLKGDHLSRAIGRLAGHHGK TKFTIENVTQTRIVLANSKVHILGSFNNIRVARTAVCNLILGSPASKVNSKLRTVAARAA E-RIKVAKPVVDLDGDEMTRIIWAWIKEKLIFPYLDVETQYFDLGLPHRDATNDQVTIDA AHAILKHSVGIKCATITPDEARVEEFKLKKMWLSPNGTIRNILGGTVFREPILCKTIPRL VPGWTQSIVIGRHAHGDQYKATDYVAKEPGKLELVFTPKGGKEQRMEVFTFKDQGGVGMA MYNTDESIIGFAHSCFQYALKKKWPLYMSTKNTILKRYDGRFKDIFQEIYEAKYQKDYEG AGIWYEHRLIDDMVAQAIKSNGGFVWACKNYDGDVQSDVVAQGYGSLGLMTSVLMCPDGK TIEAEAAHGTVTRHYREYQKGRPTSTNPVASIFAWTRGLEHRATLDGNPDLARFCQVMEK ACVDTVDGGRMTKDLAGCIYGLKNVKENQYVSTSDFLDAIKEEFE--KYLSKLFRQKEIR ILMLGLDAAGKTSILYRLKLGQSIKSIPTXGFNVETVVYRNIKFSVWDVGGQEKIRPLWR HYYVGTQALIXVVDSADRDRIDEARQELHKIINDREMRDALILIFANKQDLPQAMKPAEI QDRLGLLRLRDRNWYVQPSCAAS-----------------FGDLKSAAGLKSLNNFLAER SYIEGYQPSQADVSVFGALNGPSSDLAHALRWYNHIKSYGSDTKNFPGAATTVST----- -ADDDGDDDFELFGSAVEKLKQERLAAYEAKKAPALIAKSSIVLDVKPWDDETDMAKVEE CVRSIVADGLLWGASKLVPLAYGIKKLQITCVVEDDKIGTDFLEEEITKFEDLVQSVDIA AFNKIQVKEIRDITRIERIGAHSHIRGLGLDDALEARQVSQGMVGQVTARRAAGVIMEVI REGKIAGRAVLIAGHPGTGKTAIAMGMAQALGADTPFTAIAGSEIFSLEMSKTEALTQAF RKSIGVRIKEETEIIEGEVVEIQIDRPATGTGAKIGKITLKTTDMETIYDLGQKMIESLT KEKVQAGDIITIDKATGKITKLGRSFTRARDYDAMSANTRFVQCPEGELQKRKEVVHTVT LHEIDVINSRTQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIVPGVLFIDEVHM LDIECFSFLNRALESDTAPILVVATNRGITKIRGTQYTSPHGIPIDLLDRLLIISTTPYD DKEISQILKIRCEEEDVEMSDDALTVLTRIGKETSLRYAIQLITTASHVCRRRKGAEVGV EDIKRVYSLFLDESRSTQF------------MAQYDLITRMGQYLDRHLVFPLLEFLSVK QIYDESEMLKGKLDLLSNTNMVDFAMDVYKNLYPDKEVPQSLKDKRSSVVAELKRLQSET EHITKLFEDEEISIQNTRDGRQLYEYLSKTYDFKMEMLDTLYRFAKFQFECGNYSGSAEY LYIVRVLLPPTDRNYMNVLWGKLASEILMQDWDAALDDLNRLREVLDSPLILLQQRTWLI HWSLFVFFNHPKGRDLIIDMFLYSPQYLNAIQTMCPHILRYLTTAVITNRQLLKDLVKVI QQESYTYRDPITEFLECLYVNFDFDGAQQKLRECETVLVNDFFLVACLDDFIENARLFIF ETFCRIHQCISISMLADKLNMTPDEAERWIVNLIRNARLDAKIDSKLGRVVMGTQAVSPY QQVIEKTKNLAFRSQMLVMNLEKKLATKDMGVTVDTIRPGDGVTFPRNGQTVVVHYTGTL TNGTKFDSSKDRNRPFEFKIGQGQVIRGWDEGVAQMSVGQVAKLTCTPDYAYGARGAGGV IPPNATLIFEVELLGLKMPKYYCDYCDTYLTHDSPSVRKTHCGGRKHKENVCIYYQKWLE DQVQKLVDDTTAAFKAGKIQNNPFAQAGVAIPPPASLQARPPAPGAKMPGPPGILGGPP- -----PMGPMPPMMGLP------------------------------------------- --VYEHIYDTVDVSGSTEVRANATAKATVAAFAASEGHAHPRVVELPKTAEGLGFNVMGG KEQNSPIYISRIIPGGVADRHGNLKRGDQLMSVNGVSVEGEPHEKAVELLKAAQGTVKLV VRYTPKLLEEMEARFDRQRTARRRQ-------------VYFEERFWRSRWVESTHKGSEA GVFGWTAGKFYGDAEEDKGLQTTQDARFYAISSKFDKPFSNEGKTLVIQFSVKHEQEIDC GGGYVKVFSSDLDQKDMHGDTPYHIMFGPDICGYSTKKVHVIFNYKGKNLLTKKDIRCKD DTLTHLYTLIVRPDNTYEVKIDGKKEESGTLEADWDFLAPKKIKDPEAKKPEDWDERENI DDPDDTKPEDWDKPEHIPDPDAKKPEDWDDEMDGEWEPPMIDNPEYKGEWKPKQIPNPAY KGKWVHPEIDNPEYQPDDQLYRYSDIGAIGFDLWQVKSGSIFDNVLVTDDEKYAEKLADE TWGKSKDDEKKAKEKHDEEERKKREEEDKXKEEDEKNKDDEEEDMDTPVPEPSMYIVKAI LILDNDGNRLIAKYYDNTFASAKEQKNLFNKTHRANAEIIMLEGLTCLYRSNVDLFFYVV GGAQENELILVSVLNCLYDTISHMLRKNVEKRALLDNMDGVFLAIDEICDDGIILESDPI AVAQRVAFRSDDIPLGEQTVASVIQSAKEQIKWSLLKMNIFRLFGDLSHLFAVIILLIKI WKTRSCAGLSFKSQIMFAVVYTTRYVDLFTTFVSLYNSVMKLIFIGSSYATIFLIIRKFR ATYDRNHDTFRIEFLMLPLAGLAVLINHEFSFMEILWT---------------------- ------------------------------------------------------------ ---------MKIEEVKSTTKAQRIAAHSHVKGLGLDENGVALQTAAGLVGQEHAREAMGI VLQMINSKKMAGRAVLLAGPPGTGKTAVALALAHELGNKVPFCPMVGSEVYSSEIKKTEV LMENFRRAIGLRIKETKEVYEGEVTELTPVETENPMGGYGKTISHVVIGLKTAKGTKQLK LDPSIYESLQKEKVEAGDVIYIEANSGAVKRQGRSDTYATEFDLEAEEYVPLPKGDVH-K KEVIQDVTLHDLDVANARPQGGQDIISMLGQIMKPKKTEITDKLRKEINKIVNKYIDQGI AELVPGVLFIDEVHMLDIECFTYLHRALESAIAPIVIFATNRGKCAIRGTDDLISPHGIP LDLLDRLMIIRTMPYTQDEMQQIIRIRALTENIQIDDESLENLATIGVRTTLRYAVQL-- ---------------------------------------------DFEADEEGDQGILKL KERAKQRKGRGF-TRTGVEEYESMDVSGSGPSRSVEGWILFVTNIHEEVQEEDIRDKFAD YGEIKNLHLNLDRRTGFVKGYALVEYDTFKEAQQAIDNLNGAEVAGQKINVDWTFVQSGS KRKMSYQLYRNTTLGHTLQESLDDLIQLNQITPQLALKVLLQFDKSINVALSQKLKNKYT FKGQLNTYRFCDNVWTFVLNKVEFRSVDKVKIVACDGKGTFLFTSESVGEGHPDKICDQI SDAVLDAHLQQDSNAKVACECAAKTGMIMLLGEITSQAHVDYQKVVRDAIKYIGYDDSSK GFDYKTCNVLLALEEQSPNIAQGVHVGRSEEDIGAGDQGLMFGYATDETEECMPLTIVLA HKLNAKIAELRRSGVLWWARPDSKTQVTCEYRMQKGACIPLRVHTIVISIQHSEDIPVEQ LRSDLMEHVIKAVVPHQYLDDKTVYHLQPSGKFVIGGPQGDAGVTGRKIIVDTYGGWGAH GGGAFSGKDFSKVDRSAAYAARWVAKSLVHAGLCKRVLVQVSYAIGVAEPLSIFVSSYGT GLKSDAELLKIVKANFDLRPGKIVKDLELKRPIYQKTACYGHFGRPEFTWEQPKILQFMA GSALKRLMAEYKQLTLNPPEGIVAGPISEENFFEWEALITGPEGTPFEGGVFTARLTFPS DYPLSPPKMKFATDLFHPNIYADGRVCIS------------------------------- -------------------------------------------MRIEKCYFCSSPIYPGH GTTFVRNDCKVFRFCRAKCHSAFKKKRNPRKVRWTKAFRKSAGKELGVDPAFEFEKRRHV PVKYSRELWQDTMQAMKRVEEIKSKRQNQFIRNRLKKGKELRKADDIKEVEKNIHIIKAP ---MAVYKVVMVRHGESAWNAENRFCGWHDADLAESGVEEAKRAGQMLKEKGLSFDVAFT SVLKRAIKTLFLIQDGLDLHWIPVHRHWRLNERMYGALQGLNKAETAAKHGEEQVQIWRR SYDTPPPPVDESSEHFPGSDPKYQYVDVRLIPRTECLKDTVARVLPYWYDTIVPEIKKGQ RVLIAAHGNSLRALVKYLDNMSDADIMALNIPTGIPLVYELDKDLKPIRHYYVASDEEVK AAIAKVAAQGKAKMEQQDTFYSKSEYIETASGNKVSRQSVLCGSQNIVLNGKTIIMANCI IRGDLANVRIGRHCVVSQNTVIRPPFKKFSKGVAFFPLHIGDHVVIEEGTVVNAAQVGSF VHIGKNCVIGRRCVLKDCCAVADNTVLPPETVVPPFTVYSGSPGMSFAVGTRNYRTF--K KHIAGGARQFDTMSYSVATLGSQDLRLAVMLPEGEDLNEWVAVHTVDFHRQVSMMYGTLT EYCTDERCPVMSAGRRYEYLWADGTTIKKPIKCSAPRYIDYLITWVQDQLDDETLFPSKI GVPFPRNFLQCARTILKRLFRVYAHVYHEHIEDVIRLKEEIHLNTSFKHFILFIKEFNLV DAKELAPLEDFIERI----MGIDIRHNKDRKVHRKEPRSNDIYLRLLVKLYRFLARRTNA KFNKIVLKRLFMSRMNRPPLSVARLCRMMKKPGRENKTAVVVGTVTDDTRIFEIPKLKIC ALHITEKARGRILKAGGEILTFDQLALKAPKGQNTVLLQGRRTAREANRHFGPAPGVPHS HTKPYVRSKGRKFERARGRRASRGYKNELKQGSHQTSYHIADTVNLLKHVIGESVWKSAS DLMKIVKDESRKIIAAHPSETVIGNMTRRVLKIIREECVIESINELIEELDACVQALEHI HANEVIVTVEHFLKKKFHVVVVEYDGHKLAKSLAEGGVETTIITDSAVFAMMSRVNKVIV GTHTIMADGGLKAFGSHAIALAAKYYSVPFVVCASLFKLSPLFVRSYDESFNQFVSPENV YNPVFDYVPPDLVTLFISNIGGNAPSYIYRLVSELYSMIIPVRCFTCGKVIGNKWEAYLG LLQAEYTEGDALDALGLKRYCCRRMLLSHVDLIEKLLNYAPLEKRSPEPVEGRKHTDVQT ELYLEELADRIEEADVECQ----------------------------------------- -------------------------------------------------------EKEQR MQQQAEAMRKENETAEKIAARAFAQSYLADLVPSVFDMLSVNGYFYDPVERGVENEFMPW LMEAVEEKLQKSVLSRNLLDGLLRDVVRARFEQFAK--------EYKVVGRMMPTDKMRT PPIYQMRIFAPDRPQAKSRFWFYASMLRKVKRTQGEILCCNQVCEKKPLAIKNFGVWLRY DSRSGSHNMYREYRDLTTGGAVTQCYRDMGARHRARPGSIQIMRVQVIPASKVRSKNLRQ FLDSKIKFPLPNRYQRRLHYPRFTTKRPHTTF------------NIGRPNSPWTIYRPHL PMLTSLTHRVTGISMGVVLYSAAVAVFLAPGDFPSYIEFVKNLHLSPALLFPAKTICAFP LVYHYINGIRHLAWDAGYGYELKTQYKTGTIIFASLSYW--------------------- --------------------EEQIHELFNRAGDVKRIIMGLDKFRKTPCGFCFIEYYTRE EAENAMRYINGTRLDDRIVRTDWDAGFIEGRQYGRGKSGGQVRDEY-------------- -----RSNYTLKYTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGH KLGISDVAWSSDSKLLVSASDDKTLKIWDFATGKCFKTLKGHSNYVFCCNFNPQSNLIVS GSFDESVRTGKCLKTLPAHSDPVTAVNFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYQGHKNEKYCIFANFSVTGG KWIVSGSEDNLVYIWNLQTKEVVQKLAGHSDVVLCCACHPTENIIASAALENDKTIKLWR SD-MIIYKDHFTGDELFSDSFPGVVYKVKGKDSKAIGGNASQGIDVVMNSKKDYMTHIKG YMAEVKKYQFFCGLALVKWETPYLYFFKHG------MAVEFNGGVVVAADSRTTTGAYIA NRVTDKLTPITDKIYCCRSGSAADTQAIADIVASQLSLHQVQFGEDPLVKTAASLFQEMC YNYRDQLSAGIICAGWDRKEGGQVYLIPLGGLCVRQPMAIGGSGSTYIWGYVDAVDTKSM SETDCVAFVKRAVSLAIQRDGSSGGVVRLAVITKDGVKREVVLPHEQP------------ ------------------------------------------------------------ ------------KLQFSLDYDFQKGELTVGVIQACDLPAMDMCGTSDPYVKVYIMPDKKK KVETKVHRKTLNPVFNESFVFKLAYSEVGAKTLVFAIYDFDRFSKHDQIGQVIIPLNTVD LGRVLEEWRDITSPDNDAEKENKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSD PYVKLSLVVGGKRVRKKKXTIKKCTLNPYYNESFTFEVPFEQIQKVQLVITVVDYDRIGT SDPV--------------RHWTDMLANPRRPIAQWHVLHEV----MVLADLGRKITAALR SLSSATVINEEVLNAMLKDICAALLAADVNVMLVKKLRENVRSVIDFDEMAAGLNKRRMI QSAVFKELVKLIDPGVKAWQPVKGQINIIMFVGLQGSGKTTTCTKMAYYYQKKGWKTCLV CADTFRAGAFDQIKQNATKARIPFYGFMTKGSEQESMARLKKLMTIMDS----------- ----------------------NDQELDSHE--GAKLFSRGRVTRVARGAGVSSSAVQEL LSQKFAQMVKKMGGIKGLFK-GGDMAKNVPAQMAKLNQQMVKMMDPRVLQSMGGVAGLQN MMKKFQQGA---------------------------FGVQAQTVAMDFNKVFDMGPHLFV GLAGLATDIQTVSERLRFRVKLYELRENRRIKPDTLMNVVSNMLYERRFGPYFVEPIIAG LD-TNGEPYVAALDLIGCPMVAKDFAVVGTCAEQLYGMCEVVWEPDMNVDQLHEAISQAL LNSCDRDAVSGWGAKVYLIEKDKIRVRQLKARMDMTSKDYYFDSYAHFGIHEEMLKDEVR TLTYRDSMYHNRHLFRGKVVLDIGCGTGILCMFAAKAGAAKVIGIECSGIVEHAKQIVKA NGFDQVVTLVKGKVEEVELPDGVEKVDIIVSEWMGYCLFYESMLNTVLYARDKWLAPGGL IFPDRASLYICAIEDRQYKNEKINWWDSVYGFDMSCIRHVAVSEPLVDVVNPKQVVTNSC LIKEVDMYTITLDDLTFSSPFNLYCRRSDYIQAFVTYFTIEFSKCHKSTGFSTDPYSRYT HWKQTDDFITVKKGEEVSGVFHLTPNKRNIRDLDFTIDLEFNGELSSKTDTMRYKMRMVR EDRSAWKSKYFDKMIQLLDEYPKCFIVGADNVGSRQMQRIRMSLRVLMGKNTMMRKAIRG HLENNAALEKLLPHIRGNVGLVFTKGDLSDVRKIIESNKVAAPAKAGATATVDVTVPAQC TALGPEKTSFFQALAIQTKITKGTIEILNDVKLIKTGDKVGASEATLLNMLNISPFTYGL QIEQVYDSGTVFDLAILDITDDDIRKRFLEGVRNISSVSLAINYPTLVSVPHSIINAFKN LLAIAVVTDIDFKEAQTAKEAAQKGKLLAVIGDEDTCTGFLLGGIGELDKNRRPNFFVVD KNTSVSDLEEAFRVFTNRDDIAIVLINQNIAEIIRHIIDRYSKTIPAVLEIPSKEHPYDP SKDSILRRAK---------GNENSIPLELCSTFDAEEIKRLGKRFKKLDLDNSGSLSVDE FMSLPELQQNPLVQRVIELFDTDGNGEVDFKEFIEGVSQFSVKGDKLSKLRFAFKIYDMD GDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADTDGDGKISFEEFCAVVGTMDV HKKMVVDVMTYFISWDDFVKAAERLYLADPMKCRYVIKYSHGQGRLSVKITDDRECLVYR TEHAQDVKKIEKFTGLLMRHMASKDLYEEVKLYRNAREREKYDNLADLYALINTLQCLEK AYIKDSVTSKEYTAACSKLLVQIKAAFKQINDDEYPTIEEFVRKCKMNCPAAMERIREDK PITIRDDKGNTSRCIAEIVSLFITIMDKLRLEIKAMDEILPDMRELMDTMNRLSLIPADF EGKSKVGEWLQTLGGMQASDELTEAQVRQLLFDLDSSYQAFNQILHSXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSRLVEKQIGGEKNGGKR LVPKRRLPRFYSTEERPRKLRRSFSQQKRYLRASITPGTVLIPVAGKHKGKHVVFLKQLK SGLLLVTGPYHVNGCPLRRINQIYVIATKTKLDISGVKLPERLTDEYFKRKELKKPRHTE GELFDTKKEVYSVSEERKADQIEVDKQILDVVHKHPERKFLYGYLGSLFSLKSHDHPHKM VFMEFLFGKRKTPTEMLRQNQRALNKAIRELDRERQRLEMSEKKIIADIKKMAKMGQMNS VRIMAKDLVRTRQYVKKFIMMRANIQAVSLKVQTLKSQDSMAQAMKGVTRAMRSMNKQLN LPQIQKIMSEFEKQSEIMDMKEEMMDDAIDEAMGDADE---------------------- -----------------------------------AKYCDFCLGDELEXKKTGSREEMVS CADCGRCGHPSCLQFTPNMIISVKKYPWQCIECKSCGICGTSDNDDQLLFCDDCDRGYHM YCLTPQLTEPPEGSWSCHLCIEEFYG-VDRGIELYPLTNYTFGTKDAQLEKDLSVQARFD RMREEFSKAGMRRSVEGVLIVHEHNLPHILLLQVGQNFFKLPGGEILPTENYIDGLKRLL NELLGRTDQPAVDWVIEDTISNWWRPNFEASQYPYIPAHITKPKEHKQLCLVQLPERAMF AVPRNYKLVAAPLFELFDNAASYGPIISGLPQTLSRFNFIYH------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GWLTMISTMRPDIDNMDEYVRNTTARA FAVVASALGIPALLPFLKAVCKSKKSWQARHTGIKICQQISILMGCAILPHLKXLVEIIE HGLVDEQQKVRTITALALAALAEAATPYGIESFDSVLKPLWKGIRMHRGKGLAAFLKAIG YLIPLMDAEYANYYTREVMLILIREFQSPDEEMKKIVLKVVKQCCATDGVEPNYIKDEVL PPFFKHFWNQRMALDRRNYRQLVDTTVEIATKVGAAEIIGRVVDDLKDEAEQYRXMVMET IDKIMSSLGASDVDSRLEEQLIDGILYAFQEQTTEEIVMLNGFGTVVNALGKRVKPYLPQ ICGTILWRLNNKSAKVRQQAADLISRIAIVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLG SILGALKAIVNVIGMTKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGAEFVS AREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVC TTVAIAIVAETCSPFTVLPGLMNEYRVPELNVQNGVLKSLSFMFEYIGEMGKDYVYAVTP LLEDALMDRDLVHRQTAMYAIGHLALGVYGFGCEDALVHLLNYLWPNVFETSPHVVQAFM SCMEGMRIGLGPAKLLQYALQGLFHPARKVRDVYWKVFNTVYIGAQDSLVPAYPRIPNDE KNAYARFELDYIL------DDEYDLDYEEDXNSEPDVDLENQYYNSKALREEEPMKALES FQKVLELEGKEQGDWGFKALKQMIKINFRLNQYNDMMKHYQQLLTYIKSAVTRNYSEKSI NSILDYISTSKQVDLLERFYQTTLKALQEARNDRLWFKTNTKLGKLYYDREDWNHLQKIL RQLHQSCQTDDGEDDMKKGTQLLEIYALEIQMYTAQXNNKKLKALYEQSLHIKSAIPHPL IMGVIRECGGKMHLREGEYEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGIN PFDSQEAKPYKNNSEILAMTNLVSAYQNNDITEFERILRTNRENIMEDPFIREHIEDLLR NIRTQVLIKLIKPYTRIHIPFISQELNIDVAEVENLLVSC-------------------- ----------------------------VLLMGKSGAGKTSMRSIIFANYIARDTRRLGA TIDVEYSHVRFLGNMVLNLWDCGGQESFMDSYIASQRESIFSSVAVLIYVFDVESRDIER DCIYFQSCLEALMKFSRDAKVFCLIHKMDLVQQDDVDKVFHEKEAECRRLAEPMATSIWD ETLYKAWSSIVYQLIPNVQHIESSLSTFIDVIDADEVLLFEKATFLMISHTERRPHVDVH RFEKISNIIKQFKLSCSKVSTNFNSLEIRNSVFAAFIDGFTSNTYVMVIMSDPSIPSAAT IMNIKNAKKTFEKLEK-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------SSWGGYVFLINLIPLHVLALMLTGRFSHRIYVAYSTVYCIGT ILSMQISFVGFQPVQSSEHMAALGVFGLCQIHAFIDYVRSRLSREQFETMFRFLLLVAGV FIATALGKISPWTGRFYSLLDPSYAKNNIPIIASVSEHQPTTWSSFYFDLQMLVFLFPAG LYFCFKKLTDANIFIIMYGVTSIYFAGVMVRLMLVLAPVMCILSGIAVSSTLTTYMKNLD VAKKGDINYPVKNEVATAVVAMMTVFLITYTFHCTWVTSEAYSSPSIVLSARGGDGGRII FDDFREAYYWLRYNTPEDAKVMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMSS TEDKAYEIMRELDVSYVLVIFGGLTGYSSDDINKFLWMVRIGGSTDRGRHIKENDYYTPQ GEFRVDKEGSPVLLNCLMYKMCYYRFGSVYTEAGKPTGYDRVRNTEIGNKDFELDVLEEA YTTEHWLVRIYKVKDLRNRGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------KGLAEDIENEVVQITWPRKRLGEFFQTKYDWDLLAARSIWXFGPDTTGPNILVD DTLPSEVDKGLLSSVKDSIVQGFQWGTREGPLCDEPIRNVKFKILDAVIAQEPIYRGGGQ IIPTARRVAYSAFLMATPRLMEPYFFVEVQAPADCVSAVYTVLARRRGHVTQDAPVPGSP LYTIKAFMPAIDSFGFETDLRTHTQGQAFCLSVFHHWQIVPGDPLDKSIVIRPLEPQPAT HLAREFMVKTRRRKGLSEDVSINKFFDDPMLLELAKQDVMFTYGMQETFSLFDNKGDGKI YASQLGEVLRAMGQNPTEAEVKKCQEPDKRISWEMFLPILATISKNREKPVLEDFIEGFR VFDKEQNGFIHSAELRHLLTNLGERLTDDEVNELLQGHEDSQGNVNYEEFVKNVMNG--- ------------------------------VQCDTLDDLKLHLQSTDYGNFLANEAGPLT VALIDEKLKEKLVVEFTHIRNHCLPPLAAFLDFMTYGYMIDNIILLLTGTLHQRSINELI AKCHPLGSFEQMEAIHIASTPAELYNAVLVDTPLAXFFLDCLSEEDLNEMNIEIIRNTLY KAYLEEFYKMNMKLGQTNEETMGEILAFEADRRAFMITINSFGTELTKEDRFKLFPKCGR LWPDGLIALAKADDYDQVRAVADYYGEYRAMFSDIGNNPGDKTLEDRFFEYEVSLLKKAY MNQFHFGVFYAYVKLKEQECRNIVWIAECVAQRHRAKIDSYIPIF--------------- --------------------------------------------LCDLSSETDSVTSVSW NERGNLIAVGTYKGYTQIWDAAANKKINNLHGHTARVGALAWNADLLASGSRDRRIMLHD TRTVAVVPRKTLTGHRQEVCGLKWSPDHQHLASGGNDDKLFXWNTRSAGPVQTYSDHLAA VKAIAWSPHQHGLLASGGGTADRRIRFWNTITGRPLQCVDTGSQVCNLAWSKHSSELVST HGYSQNQILVWKYPSLVQIAKLTGHTFRVLYL---------------------------- ----------------AWIITGFYFNFTAQGYRYAIGWMLGDTSPYIWGNVGIGLGISLS VVGAAWGILTTGSSIIGGGVKAPRIRTKNLVSIIFCEAVAIYGIIMAIVISNSKNHYAGF SMFGAGLTVGWSNLFCGVCVGIVGSGAALADAQNSSLFVKILIVEIFGSAIGLFGVIVSI LQVTHAQMENKMAATRRLGKELQDNVDESNILQWSGLIVPESAPYNKGAFRVKIDFPAEY PFKPPKITFQTKIYHPNIDEKGQVCLPIISPENWKPATRTDQVIQALVALVSDPEPEHPL RADLAEEYTKDRKKFMKNAEDFTK---------GASETYPMQCSALRKNGFVVLKGKACK IVDMSTSKTGKHGHAKVHLVGLDIFTGKKYEDICPSTHNMQVPNVSRTEFEVIDLSESFF SMMTEDGSTRDDLKITATVWKALGEEVVKELKIGK------------------------- ---------------------------------SAKVVVTDFHNHSVKVFDDGRLRFSFG SFGQGNGQFNGPTGVAVDAAGNIVVADWGNARIQIFDSQGSFVALVDLYGPQGLTLSRDD YVIVADSGNHCSKF----MAAGPIAERNQDATIYVGGLDEKVTEPILWELFLQAGPVVNV HMPKDRITQAHQGYGFIEFMGEEDADYAIKIMNMIKLFGKPIRVNKASAHQKNLDVGANL FIGNLDPEVDEKLLYDTFSAFGVILQTPKIMRDPETGNSKGFAFINFASFDASDAAMEAM NGQYLCNRAISISYAFKKDSKGERHGSAAERLLAAQNPLSHADRPHQLFADAPPMGPGVP MMPPPPPPGQ---PAVPPPLSGSGPPPPRMPPGGRMPPPGM----------HGPPMGGLP PPGPPPGGMPPPPAPPPPPGKVEPKKVVNPLFEKRPKNFGIGQDIQPKRDLSRFVRWPKY IRLQRQLAILKQRLKVPPPINQFNMALDRQTATQLFRLMDKYRPETKHEKAARLKTQAKE RVKGKPEQPTKGPPVVRSGINTVTCLVEKKKAQLVVIAHDVDPIEVVLFLPALCRKMGVP YCIVLGRVVHRKTASCLAFTHTNPEDKTQLSKLIEAVKTNFNDRADEIRRHWGGGIMGQK SLARIAKLEKAKAKELAQKMRYVAAYLLAVLGGNNQPSEADIKKILSSVGIDADSAQLKK VVSELNGKNIEEVLAEGRAKLSTMPAAGVGGAAEAPKERKKESE-------MPITKIHAR QIFDSRGNPTVEVDLTTEHGMFRAAVPSGASTGIYEALELRDKDPKAYVGKGVATAVSNV NNIIAPALVLDVADQTAIDKIMLNLDGTENKSKLGANAILGVSLAVCKAGAAKKGVPLYR HIADLAGNAELILPVPAFNVINGGSHAGNKLAMQEFMLLPTGASNFTEAMKMGSETYHHL KSVIKAKYGQDACNVGDEGGFAPNIQNNEEGLELLKVAIEKAGYTGKIEIGMDVAASEFC KKYDLDFKNPKSDPATWLSSDQLYEVYAGFIQKYPVISIEDAFDQDDWEAWTKMNAIQLV GDDLTVTNPKRVREAIEKKACNCLLLKVNQIGSVTESIEACKLAQGAGWGVMVSHRSGET EDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIDEELGGAAKYAGKNFRHPGSPPA CGAFKSKHAGPTNFRKFYERGDFPIALEHDTKGNKIAWKVEIEKLDYHHYLPLFFDGLCE TEHPYEFLARQGIHDMLEHGGXQILPVIPQLIIPIXNALSTKNHQVMCATLKVLQHLVLS GEMIGEALVPYYRQILPVLNIFKCKNLNSGDGIDYSQRKRENLGDLIQETLEVFERHGGD DAYINIKYMIPSYESCLMNAPPTFESFLLFEGXKKVTIEKDTKVPCAAIFTINKEDHTLG NALRTQLLKDPSVLFAGYKIPHPLEAKFVLRIQTTPDYSPQEAFMNAITDLISEVSLLEE RFKEAIKE-----EDHRRKWDRDEYELLAKERLEEEEDRREPPVRRELLKPREYKVDLES KLGKSQVITKTTPSSQLGGYYCNVCDCIVKDSINFLDHINGKKHQRNLGMSMKIERSSLD QVRRRFEVNKKKMDEQ-------------------------------------------- --------------MGCSLSADDRAALERNREIEKCLKEDGQQAAKDIKLLLLGAGESGK STIVKQMKIIHEGGFTTEDNKQYKSVVYSNTTQSLVTIIRAMAILHIDFDAPEREADAKL VLDVFXRMEDTEPFSDELLAAMKRLWVDSGVHACFNRSNEYQLNDSAQYFLDDLDRIGAK NYSPTEQDILRTRVKTTGIVEVHFNFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCV GMSEYDQVLHEDETTNRMQESLKLFDSICNNKWFTDTSEAKLHKSPLTICFPEYTGAQVY DEAAAYIQSQFEAMNKSSSKEIYCHQTCATDTNNVQFVFDAVTDVIIANNLKGCGLYYHS QFTSPPQIIGNMALLPIRTQFKGPAFDIIDEAIQFFKANVFFRNYEIKSEADRTLIYLTL YISECLKKLQKCKSKVEGGKEMHSLAISRFYLPGEAQFPLNAMYSRPANKAEEDTMRAYM QQLRQEMGARIVEKVFDPETDKPSKWWMCFVKRKFM---------SGPYNYSYIFKYIII GDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVAGQKVKLQIWDTAGQERFRAVT RSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIFMVGN------------- ------------------------------------------------------------ -----------------MPMKAVCILKDSDVKGTVTLTQEGAVEVKGTITGLKPGQHGFH IHEFGDNTNGCTSAGAHFNPFSKQHGAPEDDVRHVGDLGNVIADDFTINDKLVTLTGPNS VIGRSVVVHADVDDLGRGGFEDSKTTGHAGGRLACGVIGITKMVNFTVDEIREIMDKKKN IRNMSVIAHVDHGKSTLTDSLVSKAGIIASAKAGEMRFTDTRKDEQERCITIKSTAISLY YSLPEKDLLCSFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQA IAERIKPVLFMNKMDLALLTLQLAPEELYQTFQRTVENVNVIIATYGEDGGPMGEVMVDP AKGTVGFGSGLHGWAFTLKQFAEMYSDKFKIEAHKLMKRLWGDQFYSYVRGFTQYILDPI YKVFEFCMPKEDAIALAEKLGVKLTAEEKDNQEKQLMKVIMRKWLPAGDALLQMITIHLP SPVTAQKYRMELLYEGPHDDEAAIAVKNCDPQGPLMMYVSKMVPTSDKGRFYAFGRVFSG IVQTGMKARIMGPNYVPVKSIQRTILMMGRYTEPIEDVPCGNVCGLVGVDQFIVKTGTIS TFENAHNMRVMKFSVSPVVRVAVECKNPADLPKLVEGLKRLAKSDPLVQCSIEESGEHII AGAGELHLEICLKDLEEDHACIPIKVSDPVVSYRETVSDESNIMCLSKSPNKHNRLYMKA KPMPDGLADDIEKGDVTPRQEIKERARYLAEKYDYDATEARKIWCFGPEGTGANIVVDVT KGVQYLNEIKDSVVAGFQWASKEGVLCEENMRGVRFDVHDVTLHADAIHRGGGQIIPTAR RCFYACVLTAKPRLMEPVYLVEIQSPEGAVGGIYGVLNRRRGHVFEESRIVGTPMFVVKA YLPVNESFGFTADLRSNTGGQAFPQCVFDHWQVLIVNDARKRKGLKEGVPPLDNFLDKLX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXSEVKLNSPPEDGITAVKFAPLSIQFLLISSWDSSVRLYDVNDNFMRMQYKHNDPVMD CCFQDAVHVFSGGLDNTLKQFNFNTGAESVIGNHSSAIRCVEFSPEXNAVVTGSWDSTVK LWDPRTAGPAGSLSQSDKVYTMSLCGDKLIVGTAGRRVLVWDLRNTAYVQQKRESSLHPQ --------------------------------------------------EKSTPVNAIA FPQWLQYFCNSGSDGFVFIWTAXNKKRLCQFRKYPTSISSLSFSHDGSLLAIASSYMFEE GQPEDSVFIRKVSDQEAKPK---------KTGVGGVASASDANRDRRERLRQLALETIDL NKDPYFMKNHLGSYECKLCLTLHNNEGCYLAHTQGKKHQANLAARAAKEAKDAPAQPAPE KARVDIKRFVKIGRPGYKVTKQRDPETGQQSLLFQIDLPEVVEGVHPRHRFMSAYEQKVE PPDKRWQYLLFAAEPYETIAFKVPSREVDKDSRRFWTHWNKDTKQFFMQFAFKLDPSSLP PPPPGRGPPPPPMDDDSETYRLWRIRKTIMQLCHDRGYLVTQEELDQTLDQFKQTYGDRP SEGRPKRSDLIVLVAHTDDPTDQMFVFFPDEPKVGXKTIKSYCQRMQEENITR------- ------------------------------------------------------------ --PRIQQGDPVARYFGLKRGQVVKIVRPSETAGRYVTYRLVVSKKESVGTVIGIDLGTTY SCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTTNPENTIFDIKRLI GRRWDEPSVQHDIKFYPFKVINKNNRPIVQVDVGAEAKTFTPEEISAMVLIKMKETAEAY LGKKVTHAVVTVPAYFNDAQRQATKDAGTISGLNVMRIINEPTAAAIAYGLDKKEGEKNI LVFDLGGGTFDVTLLTIDNGVFEVLSTNGDTHLGGEDFDQRVMEYFIKLYKKKKGKDIRG NNRAVQKLRREVEKAKRALSSQHQARIEIESFFDGEDFSETLTRAKFEELNMDLFRSTVK PVQKVLEDADLKKEDVDEIVLVGGSTRILKVQQLVRDFFNGKEPSRGINPDEAVAYGAAV QAGVLGGEE------------------------------------KKSQIFSTAADNQPT VTIQVFEGERPMTKDNHLLGKFDLTGIPPAPRGVPQIEVTFEIDVNGILRVSAEDKGTGN KNNIVINNDQNRLSPEDIDRMINDAEKFAEDDKKVKERVEARNELEGYAYSLKNQIGDKE KLGGKLSSDDKETIETAVNDAISWLEKNHEAEVDEFKAEKKKLEEVVQPIVGKLYQGAPP PSDEDERDELDTTIEDPELEAIKRRVREMEEEAEKIRQMQNEVEKQMSVEDKMDSDNRSV WIGNVDYGATAEELEAHFHGCGAVNRVTILCDKFTGHPKGFAYMEFAEKDAVELAMALDE SLFRGRQIQVTAKRTNRPGISTTNRPPRGRRP-SRSS-FHYGYAPRGPPRGRFRPRRSYY YSPYVLYDTMMEVKSSGTFSTLTDAVMKEKQTKAQMEDIITKADESYKKIKQLKKRIADV KWEREVEVKQRSEMIAHLKDQLQEMKAKTAMEGKYVKKVCDVSVAQTQKRCQLTEKAIHS EIEEFKSKIDEEVRVNAEIETFLRTHIEKRQELLQYWIEKHETDVEQKQKELDLLKAAKA KDLERLQELTRLYAEYEQVVVEDRIEKEKARRRADLEARELHACIKVQAWWRGVMVRRCL GPYKKKKKK--------------------------------------------------- ----------------------------------------------KAGYHFVGGAKKVI VSAPSPDAPMFVIGVNHTLYDEKHKIISNASCTTNCLAPLAKVINDNFGIVEGLMTTVHA FTATQKTVDGPSSKDWRGGRTAGTNIIPSSTGAAKAVGKVIPALNGKLTGMAFRVPVADV SVVDLTVRLEKPASYEQIKAVVKGDLKGVLGYTDEQVVSSDFITSDLSSIFDAGAGISLN DHFVKLVAWYDNEYGYSNRVIDLINYVFSRD----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------PPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSK LAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQ RAHVVVMAATNRPNSIDAALRRFGRFDREVDIGIPDTTGRLEILRIHTKNMKLATDVDLE QVAAETHGHVGADLAALCSEAALQQIREKMDLIDLEDEAIDAEVLNSLAVSQENFRWALS KSNPSALRETAVEVPTVTWEDVGGLENVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFY GPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFD ELDSIAKSRGGNVGDGGGAADRVINQLLTEMDGMSSKKNVFIIGATNRPDIIDSAILRPG RLDQLIYIPLPDEKSRIQILKANLRKSPVAKDVDLDYLAKVTHGFSGADLTEICQRACKL AIRESIEQEIRRERERD------------------------------------------- -------------FGGSTLFGSTPNYNPMKDIEVPSPPDDSVSALSFSPASISTTFLAAA SWDNNVRCWEVQPNGTVIPKAQQTHAGPVLDVTWSDDGSKIFTASCDKTAKMWDLGSNQF VQVAQHDAPVKTCHWIKAPNYSCLMTGSWDKTLKFWDTRSQAPMMTMQLPERVYCADVLY PMAVVGTAGRGVIIYQLDNQPQEFKRMDSPLKFQHRCVSIFTDRKTNPPVGFALGSIEGR VAIQYVNPANPKDNFTFKCHRTTAQDIYAVNGISFHPVHGTLSTVGSDGRFSFWDKDART KLKTSEQFDQPISCCCFNPQGNIFAYASSYDWSKGHEGFDPQKMKPHIFLRSCFDELKQS MKKMSSPSPGKRRMDTDVVKLIESKHEVTLLGGLHEFVVKFYGPTGTPYEGGVWKVRVDL PERYPFKSPSIGFMNRIFHPNVDEVSGTVCLDVINQAWTALYDLSNIFESFLPQLLTYPN PTDPLNGSAAALYLHRPEDYKKKVQEYVQKYATEAALREQESSLSDFSEDETQEMELMDE GDVLTTLKILIIGESGVGKSSLLLRFTDDTFDPEQTATIGVDFKVKTINVDGNKAKLAIW DTAGQERFRTLTPSYYRGAQGCILVYDVSSKQSFTKLDNWLGELETYSTKHEIVKMLVGN KIDKERREVTRDEGLRFARKYHMLFIEASAKTKEGVQCAFEELVEKIIQTPGLWETDGFS LARVIWSVINGSFCSYKVNTKTQKFCRNEYNLTGLCNRSSCPLANSQYATIREENGVCYL YMKTIERAAFPARLWEKVKLSRSFETALKQIDEHLIYWPKFIIYKCKQRFTKITQYLVRM RKLHLKRQKKIVAVSQKQERKETRREEKALVAAQLDNAIEKELLDRLKQGTYGEIYNFPQ TVFEKALDDDEMEDESESEEETEYVAADEFEESDVSDIELNQVRQAASPRLKKFSVYRWN PDKPGDKPHMDTYEVDLNDCGPMVLDALIKIKNEIDPTLTFRRSCREGICGSCAMNIDGA NTLACINKIDTNTSKTAKIYPLPHMYVIKDIVPDMSNFYAQYKYIKPYLQKKDQKDEDIG VKQYLQSPADRAKLDGMVDCILCACCTTSCPSYWWNGDKYLGPAVIMQAYRWIMDSRDDF KKERLDQMKDEWSLYRCHTIMNCTKTCPKGLNPGAAIAEMKLLMMGRSSDGIPKQEVRPN HTIYINNLNEKIKKDDLKKSLFAIFSQFGQILDIIARTTLKTRGQAFVIFKDINSASNAL RSMQGFPFYDKPMRIQYAHKDSDVISKMKGTFVERPKKKPSERKKKKQQPPAPAIIPEQP PHYILFLTNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENEVQSGAARDALQ GFKLTPTNPMKISFAKKMDSQGKRVVVCDNGTGFVKCGFSGANFPAHIFPSLVGRPILRS TTKINDIEVKDLMVGDEASELRSMLEVSYPMENGIVRNWDDMIALYDYTFGPSKLNINPQ NCKMLLTEPPMNPAKNRERMIEVMFEQYKFHGLYVAIQAVLTLYAQGLLTGVVVDSGDGV THICPVYDGFALPHLTRRLDIAGRDITRYL------------------------------ -------------TTVLVEQYTPPDGRVIRVGGERFXAPEALFQPHLINVESVGVAELLF NTIQAADIDIRPDLYQHIILSGGTTMYPGLPSRLEREIKQLYLERVLKGDVTKLAKFKIR IEDPPRRKHMVFLGGAVLAEIMKDRNEFWMLRSEYEEQGLRVMQKLGVA--STAGQPISC RAAVAWEASKPLSIETVEVAAPKAGEVRIKVLYSGVCHTDAYTLGGSDPEGIFPVILGHE GGGIVESVGEGVDGFTPGDHVVPLYIPQCGECKFCKNPKTNLCQKIRITQGQGLMPDGTS RFTCKGKSLFHFMGCSTFSEYTVVAAISLCKVDPVAGLDKVCLLGCGVSTGYGAALNTAK VEPGSTCAVWGLGAVGLATIMGCKVAGASRIIGVDINASKFSTAKLFGATECINPSDYNK PIQQV------------------------------XRWGVSCVIGVAGPGRDRKRRTLPL VTGRX------------------------------------------------------- --------------------------DQIPKYHFANYVGRPKHVRVMAGALEGDVFIGPK AEEHRGLLSIRYPMEHGIVRDWADMERIWQYIYSKEQLQTFSEEHPVLLTECPLNPRRNR ERAAEIFXETFGVPALFISMQAVLSLYATGRTTGVVLDAGDGVTHAVPIYEGFAMPHGVM RADAAGRDVTRHLQLLLRKEGHHFHTSAEFEIVRTIKEHACYVSVNPQKEES-------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------TQPKISKVIVHPLVLLSVVDHFNRMKKIGSVKRVVGVLLGSNRQG VLDVSNSFAVPFDEDQRDADVWFLDHDYLENMYGMFKKVNAREKIVGWYHTGPKLKPNDV TVNELVRKYCPNSVLVIIDAEPKNLGLPTEAYYAVEEVHDDGTPTTKTFEHVPSEIGAEE AEEVGVEHLLRDIKDTRAGSLSQRITNQLMGLKGLYQQLNNIRLYLDKVALGQLPVNHQI IYLIQDVFNLLPDVGLQSFVRSANIATNDQMLVVYDAAVIRTVIALHNLINNKLQNRDAE RSETKDKEMGLLLAKLWSLFSTEEHKVIIVGLDNAGKTTILYQFLMNEVVHTSPTIGSNV EEVVWKNIHFIMWDIGGQESLRATWNTYYSNTKFVILVVDSTDRERLGITKEELYRMLAC EDLRKAAVLIYA-KQNKKG--------------------WHIQACCALTGEGLYQGLEWI TNHIRRRPITIRRVPFTDHTQLPADYSATPGGTLFSTTPGGTRIIYDREFLLQFRNSPLA RNPPPNLPNIPGVT---------------------------------------------- ------------------------------------------------------------ -------------------------------------------------VTGHVKTQLIA HDXRFYDIAFSRAGXGGTCFASVGADGSVRXFDLRHLEHXTIIYEDPQHQPLLRLAWIXQ DPNYLATMAMDALEVIILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQAL IWDIQQMPRAIEDPILAYTAAGEINQIQWSSTQPDWIAICYNNCLEILRV--FSTSTKVA LLGASGGIGQPLGLLLKLNPAISHLALYDIVHTPGVAADLSHCSTPAKVTGHLGPQSLRE ALEGSQVVVIPAGVPRKPGMTRDDLFNTNASIVRDLANAAAKYSPKAIVLVITNPVNSTV PIASEVFKLNGVYDPNRIFGVTTLDIVRANTFIAQAKGLDVNFVSCPVVGGHSGITIVPL ISQCTPPVSFPQEERAALMERIQNAGTEVVEAKAGAGSATLSMAYAGHRFVDSVLQALNG VEGIVECAFVRSDETEAKYFSTPILLGKNGVEKNLGLGKMIDQEVNAIKNAMSELQKNIK KGEEFVAKN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------RYTKRDNSVVHE RTEXGHVDQVMVTINQEGYKFCKVRVRTVKTPQIGDKFASRHGQKGTCGIRYRQEDMPFT AEGLTPDIITNPHAIPSRMTVGHLIECLQGKVSANKGEIGDATPFNDAVNVKKISDLLHE YGYQQHGNEILYNGFTGRKLCAQVFLGPTYYQRLKHMVDDKL------------------ ------------------------------------------------------------ ---------------------------------------EFPGGFVFDNCARNATLEEGF KIPKAVKTGTTIVGVVYKDGVVLGADTRATEDTIVADKVCKKIHYIAPNMYCCGAGTAAD TEMTTKMISAQLELHSMNTGRVNRVCTANRMLKQFLFRYQGYISAALVLGGVDTTGPHLY SIHPHGSTDALPYVTMGSGSLAAMAVFEARYKADMDVNEAMQLVNDAICAGIFNDLGSGS NVDICVITKKVELFEPFNTANVKGQRQGKYDYPKGATEVVSEEIIIIQPDSVMSKVTFKI TLTSDPKLPYKVLSVPEMTPFTAVLKFAAEEFKVPADTSAIITNDGIGINPAQSAGNVFL KHGSELRLIPRDRVGS-----------LALIVTAILIFFVIYHLIAFDELKTDYKNPIDQ CRSLNPLVLPEYALHIFTNVLFLFAFEWITVLFNAPLILYHANRYLNRPVMSCPGLYDPT TIMNADELSRAQKEGWIKMAFYIVSFFYYLYSMIYVLVSSMGLLTILKKMKQKEKEIRLL VLGLDNAGKTTIVKKFNGEDIDTISPTLGFSIKTLEHRGYKLNVWDVGGQKSLRSYWRNY FESTDGLIWVVDSADKRRLDDCRSELAALLVEERLAGATLLVFANKQDLPGALSAENIQQ ALHLDDLKTHHWSIVGCSAVTGDNLLIGIDWLIDDISSRVFTADHSKRKVCYYYDGDIGN YYYGQGHPMKPQRMRMCHNLLLNYGLYRKMEIYRPHKATQEELTKFHSDDYIKFLRSIRP DNMSEFNKQMQRFNVGEDCPVFDGLYEFCQLSTGGSIAGAVKLNKQATDIAINWSGGLHH AKKSEASGFCYTNDIVLAILEMLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTLSFHKY GEYFPGTGDLRDIGAGKGKYYAVNFPLRDGIDDDSYEQIFQPVVSKVMETFQPNAVVLQC GADSLTGDRLGCFNLSLKGHGRCVEFVRRFNLPLLLVGGGGYTIRNVARCWTYETSLALS VDIANELPYNDYFEYYGPDFKLHISPSNMTNQNTPEYLDKIKTRLFENLRMLPHAPGVQM QDIPEDAIKEEXNPDERISICASDKRIACEEEFSDSEDEGD-GRRHRESFKHKRPDSSTF ECNICLDTARDAVVSMCGHLFCWPCLHQWLETRPHKPMCPVCKAGISKDKVVPLYGRGNA NQQDPREKIPPRPQGQRTEPENNNGFSNFGFGFQMSFGIGAFPFGLFASVFSLNDNRPAA PPPGSVHHTEDQLLSRVFLIIAVIFFIWLMIAMYSLLYKQEQAHDDSIWSCAWTRNEKDG TENIVTGSVDDTVRIWKWVNLELRHKLEGHQLGVVSVDINRQGTVAASSSLNSQIRLWDI ESGRQIKSIDAGPVDAWTVAFSNDSRFLATGSHTGKVNLYNIETAKRDVQFDTRGKFVLS LAYSPDGKFIACGAI--------------------------------------------- ------------------------------------------------------------ -----------------------------ETDEEFDKRYEQFFNRPDIDGWEVRKAINDL QGYDLVPEPKIVIAAMRACRRINDFALTIRFLEAIKEKCGPKYGDIWPYMLKEIGPTLKE LGIPTLEEIGYDKPELAVKDVYDMIVNLHGLPYNSNYDEISGFLDGCTIAGGAAGVHFCY GDDGRANGDAFVELSSADDLKQALTKHRKHIGRRYIEVYKVDQKEMEF------------ ------------------------------------------------------------ ------------------------------VYMRGLPYSSSEKDIFKFFSPIDPVRVCFE YGSGRPTGNANVDFDCEASAREAMRKHKNLIEHRYIELFYKDREKPTQIRFSNITAAKAV ADAVRTSLGPRGMDKMIQSSAGDVTITNDGATILKQMQVLHPAAKMLVELSKAQDVEAGD GTTTVVILAGSLLDAAQKLLIKGIHPTTISESFQRAAAKSEEILESVSMPVQLTDRESLL QSATTSLNSKVVSQYSSFLSPTCVDAVLRVIDPAKDTNVDLRDIKIIQKLGGTLEDSELI DGLVFNQKTAGFGGPNRVDKAKIGLIQFCISPPKTDMENQVIVSDYSQMDRVLRDERQYI LNIVKQIKKVGCNVLLIQKSILRDAVSDLALHFLAKMKIMVVKDIEREDIEFICKTLGCH PIASLDHFQPETLGTAELVEEVQTGDSKIVKITGIQNPGRTVTILVRGSNKLILEEAERS IHDALCVIRCLVKKRALIAGGGAPEVELAVRLHEYSQTLTGMEQYCFRAFAEALDVIPFT LAENAGLNPIATVTELRNRHAQGEKTFGINVRKGAITNILEENVIQPLLVSTSAIQLAAE TVRSILKIDDIVNCVMILLEFNNRIVEDTLTQKFSCAAAGKKPEAVDITIADFDGVIYHI SNPNGDRNKVQVSISLKFYRELQEHGADDLIRREYGEYMTTPEDGYNVSVLYDENLPETP DEVIRKAGLLKRNCFASVFEKYFEFQQNEKRAVIHYRDDETLYVEAKKDRVTAIFSTVFK DDDDVVIGKVFMQEFKEGRRQYQQAPQVLYSHKEPPLELQSTGAAVGDNIGYITFVLFPR HSARDNTINLIHTLRDYLHYHIKCSKAYIHSRMRAKTSDFLKVLNRARPEPKAIEKK--M LLFCPICANLLLAQEGRNCYQFACNTCSYVHNVTQKVTHRRYTSLKELDDVLGGADAWKN VDSTAETCPKCSHPRAYFRQLQTRSADEPMTTFFRCCNQDCGHNWRKTKFGDLKDEDRIF TNLYGRHDFHLKGALKRGDWYKTKEILLKGVDWIQGEVKKSGLRGRGGAGFPTGLKWSFM NKPNDGRPRYLVVNADEGEPGTCKDREILRHDPHKLVEGCLIAGRSMGARAAYIYVRGEF YNETSNLQIAIREAYEAGLIGKNACGSGYDFDVFVHRGAGAYICGEETSLIESLEGKAGK PRLKPPFPADVGVFGCPTTVNNVETIAVAPTICRRGGDWFASFGRPRNSTVMMEFDDLVA NQTALGTAALIVMNKSADVVHCIARLSRFYKHESCGQCTPCREGCNWMDKVMTRFTIGKA RPEEIDMLYELSKQIEGHTICALADGAAWPVQGLIRHFRPELERRMKEYHEK-------- EMNLQLNQTRSQRVRAAMFPETLEEGFQIPSTQIHRDQSTAVQRLAEPSQMLKHAVINLI NYQDDADLAVRAIPELVKLLNDEDQVTVGKAVIMTHQLSKKEASRHAIMNSPQMISALLR ALTGSLDPEAARHGAGTLHNISHHHQ---------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------DGVRM DEIIEGTVGNITHFGKEAQSRVMIRGLKCTPLFVQLLYSPNDNIQRVATGVLCELAAEKD GADQIVREGALGPLNDLVRSGNETLATYAGTLMMRLNE---------------------- -MSADLQWMVIRNNSSFLMKRRIFSKEANNLKGLNSFRHSGLVQRKTVGIEPTADGKGVV LVTKAVGRKLSKNFKRVELKRNARKTLATIRKVVGSKQYRKDLKMPAIR----------- -------DEPYYCSEQIHIPPELPDILKQFTKAAIRTQPKDVLAWSAAYFRAMATGEVPP VKDRLEMATATQKTDTGLTPGLLRILNRQLGSKKVVALTVVESKWHDLALPKELFDELVR LGNFTGDVEWLKFFALACSSLTEDIVGSMKLVCEILTADPEGGAARIPFPLFEKEYRYLA SIDGEIPVEHVNAVLEYLEQHVKKQEGYVQPRNFAAHGCPGLASKLDSSQREQLMEQVKV QIAIANAQELLQKMSDKCFKKCISKPGTSLDSSEQKCVANCMDRYMETFNIVQRVYIQRL QREKSRLMNRLFGRAKPKEPPPNLTDCISNIDSRGESIDKKIARLDQELVKYRDQMKKMR DGPSKNMVKQKAMRVLKQKKMYEQQRDNLMQQSFNLEQTNYGIQSVKDTKTVVDAMKISV KEFKKEYKKINIDNIEDLQDQLEDLNEQSNEIQEIMGRSYGMPEIDDDELEAELCALGDE IALDDDTSYLDEAAKAPNAPTGIPGADSVTNKDGIPVDEFGLPKIPAQ---MTPATPASP QLQNIVCTVNLGCKLDLKKIALHARNAEYNPKRFAAVIMRIRDPRTTALIFSSGKMVCTG AKSEELAKLAARKYARIVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLSHGQFSSY EPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKVRQEIYDAFDNIYPILKGFKK------ -----------------------------------------------------RILLSHF KWDREKLMERFXDGDQDKLFSECHVINPFKQPAHRVCEICFLVIQDGFAGLECGHQFCAS CWNTYLTTKIMDDGMGQRISCAAHDCGMLIDDNTVMKLVTDDRVRLKYLYLITNSFVECN PLLRWCPTPDCGHAVKVDNVEFKPVTCTCGHXFCFTCGEN-------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------LMYTYVFAYYLSKNNQXIIFEEQYKKIRMQLNRLSEYLERD ITSDMLADIKQKVQDKYRYCENRRKVLLKRVYEGYDKDLWEYQ--------LSTTERVVK SVPFPPANKLTMSEVFDTKGKPRPDVLKQHFVGEGRVTDDVALRIINEGAALMRQEKTMI EIEAPVTVCGDVHGQFFDLMKLFEVGGQPANTRYLFLGDYVDRGYFSISEKVYDACMDAF DCLPLAAIMNQQFLCVHGGLSPEIHTLDDIRKLDRFKEPPAFGPMCDLLWSDPLEDFGSE KTTEHFTHNSVRGCSYFYSYAACCDFLQQNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSL ITIFSAPNYLDVYNNKAAILKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK-- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------GRGGRGGMRGGAKVTVEPHRHEGVFIARGKEDALV TLNLVVGESVYGEKRISVEEGTKIEYRAWNPFRSKLAAAIMGGVGNIYIKPGSKVLYLGA ASGTTVSHVADIVGPEGLVYAVEFSHRSGRDLLNVAKKRTNIIPIVEDARHPHKYRMLIG MVDTIFADVAQPDQARIVALNAHSFLKNEGHIVISIKANCIDSTAAAEAVFASEVEKLEX EKIKPIEQITLEPYERDHAVVTGIYRAPPKKMDPNKLNDLASRMMKGSKGAGIGLGFLAA AGGAAYGLYQSMYTVEGGHRAIIFSRIGGVQSEIYREGLHFRIPWFQYPIVYDIRARPRK ISSPTGSKDLQMINISLRVLSRPDASQLPTMYRQLGTDYDERVLPSICNEVLKSVVAKFN ASQLITQRQQVSLLVRKELTDRARDFNIILDDVAITELTF-------------------- ------------------------------------------------------------ -----------------------HTQKLHTEEDDVNPRQKEQKNSKGITXFCIRNRHGVW VKREMEIAAQEMPGLMALRKRAQGDRPLQGAKIVGCTHITAQTAVLIETLAALGAQVRWA ARNIYSTQNEVAAALAEAGFSIYAWKGETEDDFWWCIEKCIQADNWQPNMIXDDGGDATH LMLKKYPAVFSMVRGIVEEXVTGVHRCISCQSLGKLTVPAMXVNESVTKTKFDNLYSCRE SVLDXLKRSTDVMFGGRQVVVCGYGEVGKGCAAALKGMGSIVMVTEIDPICALQACMDGF XVVKLSEVVRNVDXVITCTGNKNVVTRQYMDKXKNGCIVCNMG----------------- ------------------------------------------------------------ -------------------------------------------------------PDPDA IKMFAGQIPRYWDENDLQKLFEEFGPVYQINVLRDKLTNQSKGCCFVTFYTRRAAMEAQS SLHNIKTLPGMQHPIQMKPADSEKRV-EERKLFVGMLSKKCSETDVRMMFAPYGTIEECT ILREQNGQSRGCAFVTLSSRQCAQNAIRGLHHSRTLEGCRSPLVVKLADSQEKK--KKIQ Q--------FIAGAVGGAGSTSLSHPLDSVKVKLQTFPDLYRGGLHCIREVARKDGVRGF YRGLTPGVEASIRYMIYGLCQDVVKLTGCLSTLASCPIELVKCRMQGVAGHVIRTDGVRG LYRGFASNVARNTPGEMIFFATYEQCRMLVKKPDQFKDEIGMGSFACGSMAGIAYWVSIY PLDSVKSRIQVKTEGFRKLYHGVGYCIPRACIGSGSHFVFYETTRKLL------------ ------------------------------------------------------------ ----------------------------------------DDEDEELLRDREQSIRKLES DIMDVNQIFKDLSLLVHEQSDVIDSIEANVERLNVERGTEQLLQARNYQSKVRKRKLCLL VIVLVVIAILAIIIGA---MVNVEKGVLVECDPAMKQFLLHLDETTELGRKFVIQDLDET HLFISSDVLETLQESIDDLMDRLHFP---------------------------------- -----------------------YEKQLQQIDGTLSAIEFQREALENASTNTEVLRVMGD AAKALKAAHKNMNVDDIHNLMDDVAEQQEIANEISDAISNPVGFGQDVDEDDLLKELEDL EQESLEEKLLDV-TLPSVPIAQDDEMRELEAWAS-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -SKGXWNNTTTQKYWLDVQLRWGDYDSHDVERYARAKFLDYTTDNMSIYPSPTGLLVALD LAYNLHSAFGNWFPGCKPLIQQSMAKIMKANPALYVLRERIRKALQLYSSEPTEPYLSSQ NYGELFSNQIIWFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSV WAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKG SELQLPFQACLKVEKFGDLILKATEPQMVLFNLYDDWLK--------------------- ------------------------------------------------------------ ---------------------------------TATTTRTVNKHGDEIITSTTSNYESQT FASKTEWRVRAISATNLHLRTNHIYVSSDDIKETGYTYILPKNVLKKFIIISDLRAQIAG YLYGVSPPDNPQXKEIRCIVMPPQWGTHQTVHLPNILPAHDYLKELEPLGWIHTQPNELP QLSPQDITTHAKVMSDNPVWDGEKTIVITCSFTPGSCSLTAYKLTPSGFEWGRQNKDTGN NPKGYLPSHYEKVQMLLSDRFLGFFMSPAQGSWNYNFMGVHHDPNMKYELQLANPKEFYH EIHRPSHFLNFRSLEEGADREDLYATYDATRVNMLVNKNTKVICQGFTGKQGTFHSQQAI EYGTKMVGGVSPGKGGSKHLGLPVFNSVKEARQTTNCDATVIYVPPPAAAAAIIEAIDAE VPLIVTITEGIPQQDMVRVKRKLLAQNKSRLIGPNCPGIIKPGECKIGIMPGHIHKVGKI GIVSRSGTLTYESVHQTTLAGLGQSLCVGIGGDPFNGTNFIDCLQLFLDDPQTEGIILIG EIGGAAEEQAAEFLGQHNGANRKPVAAFIAGLSAPPGRRMGHAGAIIAGGQGGAKEKIEA LRKAGVEVTLSPAQLGSTILQAMKKAGKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXYTRFVEVGRVAYIA YGPNAGKLVTIVDVIDQNRALVDGPCSGVTRQSMNFKQLHLTQFVLFPHSARSGIVRKAW EKAEIEKKWAETTWAKKIADKEKRKNLTDFDRFKLMKAKQMRNRIIKVEFGKLRKSAK-- ------------------------------------------------------------ -------------------LGSTCCGRKGKDDGVTLASRKFVIGDYLDIAITPPRGLGKT LQTISLLGYMKHYRHSPGPHLVIVPKSTLTNWMNEIKRWVPSLRAVCLIGDQEQRATIIR DTILPGEWDVCVTSYEMVIKEKSVFKKFNWRYLVIDEAHRIKNEKSKLSEMVREFKSANR LLLTGTPLQNNLHELWALLNFLLPDVFNSADDFDAWFDTNNCLENVQLVERLHAVLRPFL LRRLKSDVEKRLXPKKETKIYIGLSKMQREWYTKILMKDIDIVNGAGKTDKMRLLNILMQ LRKCTNHPYLFDGAEPGPPYTTDKHLVDNCGKMVLLDKLLPKVKEQGSRVLIFSQMTRML DILEDYCHWREFDYSRLDGQTPHEERQDSINEFNAPGSSKFIFMLSTRAGGLGINLATAD VVILYDSDWNPQVDLQAMDRAHRIGQMKQVRVFRFITENTVEERIVERAEMKLKLDNIVI QQGRLVDQNTNKEMLNMIRHGADHVFASKDSEITDEDIDAILVRREKKTEELNKKLNELG --------------------------KQKIPGIGHWIEPPKRERKANYAVDAYFREALRV SEPKAPKAPRPPKQPSVQDFQFYPPRLFELLDKEIYFYRKSIGYRVPKDPDLGADAERVR KEEQKKXDDAEQLSEEEIAEKEDLLKGFSNWNKRDFNQFVKANEKYGRDDIESISKEVEG KTAEEVMEYSSVFWERCNELQDIERLMAQIERGEAKIQRRVSIKKALDAKMARYRAPFHQ LRIQYGTNKGKNYTEEEDRFLVCMLHKLGFDRENVYDELRTAVRQAPQFRFDW------- -------------------------------EVKASWAEQVELGDELLLPAPFEEFDEES GIRKLIEYKFNEDGKKVKIVKTYKIETRKVSQSAAKRKTLKKFGAASGDPPGPNPSNTVE DIFMQFVHAKDLNDEDPLGKLKVSCRICKGDHWTTKCPYKDSLGANAEAQRQLGKYVPPS LREGGNRKGESMSADEAATIRVTNLSEDTRETDLQDLFRPFGSISRIFLAKDKVTGQSKG FAFINFYRREDAARAIAGVSGFGYDHLILNVEWAKPSXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXVVQPSDQKKLETTQWPLLLKNFERMNVRTSHYTPLVAGCSPLQRPIDEYIKSGFINL DKPSNPSSHEVVAWIKRILRVEKTGHSGTLDPKVTGCLIVCIERATRLVKSQQNAGKEYI GIFRLHSAVEGERRILQAVEQLTGALFQRPPLISAVKRQLRIRTVYESKLLEYDXGKNMG ILWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGIQSEKDGMVTMHDVLDAQYVYD HHKDESYLRRVIRPLEALLVSHKRIILKDSAVNAVCYGAKIMLPGVLRYEDGIELNEEIV IVTTKGEAIALGIALMTTAVLATCDHGVVAKIKRVVMARDTYPRKWGLGPVASRKKQLIK DGLLDKYGKPNENTPKEWKANFVDYS----------------------MAESSWDRKRQP KASQLKTPQAINAAQRQGLEIETSKKFTAGQNKQHEAAKNVAKLDRETEELHHDTVGLDI GRLIQQGRQAKSMTQKDLATKICEKPQVVNEYESGKAIPNQAVLTKMERALGIKLRGKDK GQPL---MLKPRALTQVLAQANSDNVLSTLLLNKDGALLAYAGFDSKDARVTAAIASNIW STFEKNGI-----DPLELVCVECEEGNVVIARVANFILCTYGNKSVGLGMLKAKAQALVD YLDEPLRQVMAS------------------------------------------------ ------------------------------------------------------------ --RKGLEMFINKVAGHPLAQNERCLHMFLLDPVIDKDYVPGKVRTTRCYSAKLAEVGVLE TPKLQGKYDAGQLFIHRVFGYRGVVLFPWIGKVYDRDIATKGTKEVKGRMHTYYQVLLDT RDIPHIRVGTESVTFLSNQENGTLYSIPGLDYVGHEDVLPYRTTDSQPIHNHLFEKFLVK SALYTARDTLREWQDKNHPWLELTDIHRETTENIRVTVMPFYIGEVQQTQVYWWRYCIRL ENLGDDTVQLRERHWRIFSLSGTLETVRGRGIIGKEPIFSKAQPAFQYTSHVSLQAPSGH MWGTFKMERQDGSTFECRIPPFSLESKHEDN------------------------QTCLG DNPYLRMTKEKYGKECKTCARPFTVFRWNPGSKARFKKTEVCQTCSKMKNVCQTCLLDLE YGLPVQVRDAALKIQDSLPKSDVGKEYYQQNMEREIANTDGTVAVGNVGKALAPSDMLLK LARTTPYYKRNRPHICSFWVKGECKRGEECPYRHEKPTDPNDPLADQNIKDRFYGINDPV AEKLLRRYDSMPKLDAPEDMDVFLMVRRKKVSIFLDAKESTTVLELKKMVRGITKRAIED MKLYKDSRTLSDVGFTSSTARAQTPATVGLAFKAFEPLEITDLSTPPDLPEVMKPQDSSS -HIQDHLYRYQAVLLRARFDEHKDEDMVKAKKVLLAAEHEFHTKMHPQPMKFPNSPGGTA YGREPYVADDIFDMWHPLERAQYPEYFARREQRKKEYIERWEKKYGKAD--------KIG EGTYGVVYKGRHKATNRTVALKKIRLESEEEGVPSTAIREISLLKELVHPNVVTLEEVLL EDGKLYLVFEFLSMDLKKYMDSLPSGQLMDKMLVKSYLYQILQAMLFCHQRRVIHRDLKP QNLLIDSQGIIKLADFGLARALCIPVRVYTHEVVTLWYRAPEVLLGAARYSTPVDIWSIG CIFAEMASRRPVFRGDSEIDQLFRIFRTLSTPNEESWPGVSQLPDYKSTFPSWRNNNLPQ TVDDVGMELLQSMLKYDPSQRISAKAALNHPYFASRLFSALGKLGIGLAVAGGVVNTALY NVDGGHRAVIFDRFSGIRQTTVGEGTHFIIPWVQKPIIFDIRSQPRSVPTITGSKDLQNV NITLRILFRPLADKLPGIFTNLGIDYDERVLPSIVNEVLKATVAQYDASELITQREMVSA KITDELTSRAAQFGIMLDDISITHLTFGREFTEAVEMKQVAQQDAERARYLVEKEEQLKL AAIIRAEGDSQAAALLAKEFSDAGEGLVELRKIEAAEDIVYQMTQSPNVIYLPHGQNVLL NLPMKTLHHSQAINIIDGVEVSVKSRKVIVKGPRGTLRRDFRHMAVDIRKIGKNELQVEK WFGNRKELAGVKTVCSHIENMMKGVTKGYRYKMRSVYAHFPINTTISEKDTVVDIRNFLG EKFNRQVRMLPGVKCYASKDLKDELILEGNDIELVSRSAALIQQSTKVHKKDIRKFLDGI YVSEKGNISQDMGCVMSKEDRAAVERSKQIDARLEVDARNASRKVKLLLLGAGESGKSTF IKQMKIIHEKGYSKTECLSYVPVIYSNTIQSLLAILRAMGRLKIGFAQTGAEKDARQFFN VNA-SDDVSITEELAAIMKRLWNDGGVQECFRRSREYQLNDSAEYYLQSLDRISQQSYVP SDQDVLRTRVKTTGIVETRFTLRGLDFEIFDIGGQRSERKKWIHCFEGVTAIIFLVALSE YDLTLIEDQEMNRMTESMQLFDSICNNHWFIDTSIILFLNKKDLFAXKIKTSPLTLCFPE YKGNNTYEEAGAFIKERFNQRRETKDIYTQFTCATDTRNVQFVLDAVTDVIIXNNFRDCG LF---------------------------KKPDPQNMXIRELPQASSALFFKYNEQLGPP YHVLIDTNFINFAVKYKLDIIQSMMDCLYAKCIPYVTDCVMAELEKLGRKYRVALRIVKD ER---------------------------------------------------------- ------------------------RYLLESGFTHAAYTFGIESHISQSNINGSVVPPAAL LNIIQKGLQYTEAELSIAEDGTERSIESISLIDAVLPEVIEQRKQGAMKGANGEENAEMM DLDSAMEIPSSKVSVLRGHESEVFICAWNPTNDLLASGSGDSTARIWNMNENGNSSQLIL RHCIQKGGAEVPSNKDVTSLDWNCDGQLLATGSYDGYARIWNTEGKLVSTLGQHKGPIFA LKWNKK-------------------------QSQFHSAPALDVDWQSNNTFASCSTDQCI HVCKLSSDKPIKTFQGHTNEVNAIKWDPQGNLLASCSDDMTLKIWSLKQDTCVHDLQAHN KEIYTIKWSPTGPGTNNPNAPLILASASFDSTVRLWDVERGQCVHKLTKHLEPVYSVAFS PDGKHIASG---------NVQTGSLIHTYRGTGGIFEVXWNHRGTKVGAXASDGSVFVLD LRKSSTDLASLFECPVCFDYALPPIMQCQSGHIVCSHCRPKLQFCPTCRGALGNIRNLAM QK---------------------------------------------------------- ------------------------------------------------------------ -------------------------------------DGVQAAIAATDCLMFDVNVAQMF ADNGNLSINVTI---MAYRTIQQEYMQIPPVTRAYTTACVLTTVAVQLELITPFQLYFNP ELIVRNYQFWRLITNFMFFGTIGFNFLFNMIFTYRYCRMLEEGSFRGRTADFVFMFLFGG ALMTVVVSLVFLGQAFTIMLVYVWSRRNPYVRMNFFGLFSFQAPHLPWVLLGFSLLLGNS VIVDLMGIAVGHIYFFLEDVFPQQPGGFKMLKTPALLKRLCDSAPEDPDYRTLPPGGFNW GGGLDVYSDEGFRGDGRQSNEIRRIRCKVGVYSQADGSAYIEQGNTKALATVYGPHEVHG QRSRHDRALVNCQYSMAVFSRGERKRRPRGD----------------------------- ------------------------------------------------------------ ---------------------------------------------------MTSSYYFVI VGHQDNPVYEIEFFPPSRANDPKKDDHRHLNQFIAHAALDLIDEQMWATNSMYLKVVDKF NEWFVSAFVTASRQRFIILHDVKNEEGIKNFFQDVYETFIKLSMNPFYDMNTPIKSANFD KKVQFFGRKNL--QFRFAHTDVNFPDFSPYRRDAVKANRKAFTYLMLAAGAVPATYITKN VVQQFLMTMSASAEQLALAAIEVKLDQIPEGKNMTFKWRGKPLFVRHRSADEIEREQGVA LATLRHQEHDNDRVRKPEWLVLIGVCTHLGCVPIANAGDFGGYFCPCHGSHYDASGRIRK GPAPLNLEVPEHKFVDDNTLVVG------------------------------------- -----QLDKMGYNIGVRLIEDFLARSSVGRCNDFRETADIIAKIGFKMFLGITPVVSNWS ASGDEFSLLIENNPLIDFVELPDGHNKLNYSSILCGALRGALEMVQLEVAVWFVQDQLKG DNITEIRLKFIKRLEDAVPAGEDDDVKAFLAQAKEEFNKKWDEPGQNNASLDDFDRIRTL GTGSFGRVMLVQNKATKSFHAMKILDKQKVVKLKQVEHTLNEKRILQSVSFPFLVRLDYS FKDNSNLYMVLEFVGGGEMFSHLRRIGRFSEPHARFYGAQIVLAFEYLHSLELVYRDLKP ENLLIDPQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIY EMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADIKDLLRNQLQVDLTKRFGNLKNGVN DIKQHKWFANMDWIALYQKKIEAPFLPKSKGPGDPSNFDTYEEEPLHISSAEKCAKEFAD FMLADTLLILFISVATALLGEGLTWLMVYRTSKYQKLKSEVEKQSKKLEKQKESIAEASD RSQKKKLERQEEKLKTNNRDLSMVKMKSMFAIGFAFTALLSMFNSIFDGRVVAKLPFVPI SLLQNISHRNLIGDDYTDCSFIFLYILCTMSIRQNIQKMLGFAPSRAANKQAGGFFATCG RMFDAWSEVDQVQFVQMLLMRMCHHQHGQIDAFLKPMLQRDFISSFPAKGLDHVAEHILS FIDAESLLSAELVCKEWHRVVCDGHLWRKLIEYKVLIDPLWRGLANRKGWIKYLFRLKSG EKHREHKFYKSLYFEVLQDIQHIENNWRTGRHLLQRIQCHSETSKGVYCLQYDDKKIVSG LRDNTIKIWDRTSLQCVQSLQGHTGSVLCLQYDDQVIISGSSDATVRVWNLHTGEMVNTL IHHCEAVLHLRFWEGIMVTCSKDRSIAVWDMHSANEISLRRVLVGHRAAVNVVDFDNRYI VSASGDRTIKVWCTKTCEFVRTLNGHKRGIACLQYRDKLVVSGSSDNTIRLWDVDCGACL RILEGHEELVRCIRFDNKRIVSGAY----------------------------------- -------------------------MAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAYNS TFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKS FENIRNWIRNIEEHASSDVEKMILGNKCDINERRQVTRERGALLASEYGIQFMETSAKAS INVEEAFITLSRDIKAKLDKK---------------------QSQEAARGNGTSMISLII PPRDQISRVARMLADEFGTASNIKSRVNRQSVLGAITSVQQRLKLYNKVPTNGLVVYCGT VMTDEGKERKVNIDFEPFRPINTSLYLCDNKFHTEALTALLADDSKFGFIVMDGNCALFG TLSGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAETAVQLFITNDRP NVAGLVLAGSADFKTELSQSDMFDARLQAKVIKIVDVSYGGENGFNQAIELAGEALGNVK FIQEKKLIGKYFDEISQDSGRYCFGVGDTLKALEMGAVEILIVWE-------------TG ETKLLYLEDEEEKDKTHFTDKETGIELELIESIALLEWLANSYKGYGAILEIITDKSQEG AQFVRGFGGIGGILRYQVDFQTMELLDDLGADFDLDEY---------------------- ------------------------------------------------------------ -----------------IESTHWLDHIKQXLAGAVRVADKVESNKTSVLVHCSDGWDRTA QLTALAMLMLDPYYRSLRGFQVLIEKEWLSFGHKFAQRVGHGEDKHSDADRLAVFLQFMD CVWQMTRQFPNAFEFNETFLISILDHLYSCLFGTFLYNTEQQRVKENVKSKTVSLWSLIN SKTPLFLNPLYQHVLYPVASLRRLEVWTAYYMRWNPSAVPQEPLHIRNMEL--------- -------------------------------NVFPRAKPAPDDKVLTEALLKRAQELTPG TQEQTAVLNLVTKIQTVLDNLVVAPALFEAAQLEEVRQVGSHKKGTMMAGHEVADIVVIL KTLPTLEAVQALSNKVTDDLRAGDPHEAFTAVLNDGGFEVSSSDASVKVLIATIPPNIKK LDPQLHLDAKLMQGHLTAIRHARWFEENAFHSGIKVLIRLIRDLKTRFEGLSHLTPWMVD LLAHYAVMNNPSRQPLPINVAFRRVLQLLSAGFFLPGSAGITDPCEQGALRIHTVLTLEQ QDQVCYTAQTLLRVLSHGGYKQILGFEEYPNIIADMTVWDGVIVTPSDKAYEKREK---- -------NNLMKTLLVLQEETGISLNTVDSVESFVSDISNGHWDTVLQAIQSLKLPDQKL IDLYEQIVLELVELREVGAARSLLRQTDPMIMMKQQYPDRYIHLENMLARSYFDPREAYP EGQSKERRRAAIAQALSGEVNVVPPSRLLALLGQSLKWQQHQGLLPPGTTIDVFRGKAAV REQEEEKYPTQLNRTIKFGQKAHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLK YQAQDNYMMMDDAVLCLGFSRDSEMLASGGQDGKXKVWKILTGQCLRRFERAHSKGVTSV CFSKDNSQLLSASFDMTIRIHGLKSGKTLKEFRGHTSFVNDAEFSADSHYVISASSDGTI KVWNIKSTECQNTFKSLGGTTGTDITVHSIHPLPRNMEQFVVCNRSNTIVIMNMQGQIVR SFSSGKREGGDFVCCSLSPRGEWIYGIGEDLVLYCFNITTGKLERTLTVHEKDVIGIIHH PHQNIIATYSEDGLLKLWKPMAQVVNVVPRLIDVAVPKLLVFWKYAKVELRPPREFSEVS KGFGNLISVRTQRWRNVTVKEATLVAFEVACWFWVGEVIGKGSLVGYQIPGTIDFDVH-- ------------------------------------------------------------ -------------------------VFAKLLGNDPYGRISVMQFFNYVMRKVWLHQTRIG LSLYDVAGLGYLRESDLENYILELIPTLPQLDGLEKSFYSFYVCTAVRKFFFFLDPLHTG KVKIQDILASSFLDDLLELRDEELPKDMQESNWFSAPSSLRIYGQYLNLDKDHNGMLSKE ELARYGTGTLTSVFLDRVYQECLTYDGEMDYKTYLDFVLALENRREPQALQYLFRLLDVQ NKGHLNMFDLNYFFRAVQDQMRQHSQEPVSFDDVKNEIFDMVKPDDPLRITLQDLIRCNN GHIVVSILIDLHDFWTYENREVEMVREHPFEVGPRYTNLAYIGEGAYGMVVSAFDHVTKT KVAIKKISPFEHQTYCQRTLREIKILTRFKHENIINIQDIIRAPTINEMKDIYIVQCLME TDMYKLLKTQKLSNDHICYFLYQVLRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFG LARVADPSRDHTGFLTEYVATRWYRAPEIMLNSKGYSKAIDVWSVGCILAEMLSNKPLFP GKHYLDQLNLILGVLGSPSQEDLNCVLNDKARGYLQSLPQKTKIPWNKLADPKALDLLDK MLTFNPNKRISVEMALAHPYLEQYYDPSDEPIASEPFTFETELDDL-------------- -----QLTPPKTTPEWVKFCKQLFGGFSLLLWLGAILCFIAYSIQASTSEDPAGDNLYLG IVLTAVVIVTGCFSYYQEAKSSRIMESFKNLVPQFAIAIRHGEKVNLKAEELVVGDLIEV KFGDRVPADIRVISAHGFKVDNSSLTGESEPQSRSAEFTNDNPLETKNLAFFSTNAVEGT CRGIVVNTGDRTVMGRIANLASGLETGETPIAREIAHFIHLITGVAVFLGVSFFIIAFIL GYFWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTI CSDKTGTLTQNRMTVAHMWFDNHIVEADTSEDQSSATYDRSSPTWMALARVAMLCNRAEF KQGQDGVPVLKRECNGDASESALLKCVELSIGNVSSYRKANKKVCEIPFNSTNKYQVSIH PKDRRYLMVMKGAPERIIDRCATILMNGEEIPLTDPMRDQFNEAYMELGGLGERVLGFCD FMLSDDEFPRGFAFNADDANFPLTGLRFVGLMAMIDPPRAAVPDAVAKCRSAGIKVIMVT GDHPITAKAIAKGVGIISEGNETVEDIAARRAIPVNQVNPRDAKAIVVHGTDLRDMTPAQ IDSILSHHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIA GSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLLFIIAD IPLPLGTITILCIDLGTDMVPAISLAYEQAESDIMKRVPRDPINDKLVNQRLISMAYGQI GMIQASAGFFTYFVIMGENGFKPSLLFGLRRDWDSKAVNDLQDSYGQEWTYAQRKVLEFT CHTAFFASIVVVQWTDLIICKTRRNSVIHQGMLNHHMTFGLFFETSLAAFLAYCPGLDKG LRMYPMKWTWWLVPMPFSAAIFIYDEVRKFILRRHPGGWVEQETYYSFKAFSSGKKFLYG TSAGAVGLGVALQSAELHPPKFRWSHDGMLDSLDHASMRRGYQVYKQVCAACHSMNFMYY RNLVGTIMTEDEAKAEAADIMVLDGPDETGAMFERPGKLSDRFPNPYPNDEAAKAANNGA LPPDLSFITGARHGGENYVFSLLTGYCDPPTGVDVPEGMHYNPYFPGGLISMAKSLFNEV VEYDDGTPASASQMAKDVSTFLRWSCELEHDERKRMGVKVLMLGLILLAFYYKRHKWTVL KSKKIV------------------------------------------------------ -------------------EDRIALRMIEDAEASGKLRPGDTLIEPTSGQXGIGLALVAA VKGYRCVIVMPEKMSNEKADILAALGAQIVRTPAGA-IDSPESFYSVAYRLLNEVPRSHL LNQFSNPSNPLAHYEATAEEILEACDGHVDMFVAGAGTGGTLTGVAMKLKQRCPNCKVIG IQPSDSAISGTEDSTMVEVEGIGYDFVPVVSNREFVDRWYKSEDMPTFQMARRLIREEGL LCGGSSGAAMYCALQAAQEFNMTSAERIVVVLPDSIRNYMTKYLNDDWMLARKYMSDAGS DEERGPNLGEYEGERNEKEQRHGHGKALLPNGDTYEGAYENGMRSGMGTYRFKNGARYTG EWLKNKKHGIGTFIYPDGSKYEGNWVDDQRSGSGKYYYVNNDTYEGEWRNHVHHGYGTYT YADTGSRYVGMWKDGRRDGHGELIHANHKYVGKFNDDKPLGSGKYIFDVGCMQYGEYV-- -----------------------------------------AIVQKSEQHSSVSDVAYLR RMAVHKNFRRQGIAVKLLETTVAFCRHHGYDRIELITTDIHKAAMRLYCKFGFTCSVYKP RYYIFGL----------SVDSLMFMLSANQRKCLKEEIHKDVLVTGDYELSDAPGQTTNL KVTDSKGHVLFNKDDATKGKFAFTTEEYDMFEICFESKIPHGGHGADREVTINVKRGVEA KNYGDLAKAEKLKPMEVELKRLEDLSESIVNDFAYMRAREEEMRDTNESTHSRVLYFSIF SMCCLLGLATWQVLYLRRYFKAKKLIE--------------------------------- -------------------------------------MLYGWSNAGVVGMTKESIWFGSS LGVPVFVVVTKIDXCPSQILAETLQMLHKILKSPGCRKMPVLVQTVDDVVVSATNFTSER MCPIFQVSNVTGENLALLRMFLNLLSTRMPTAPAEFQIDETFAVPGVGTVVSGTTLRGHI KLGDTLLLGPDLAGTFIPIVIKSIHRKRMPVKEVKAGQTASFALKKSQLRKGMAMVSPAI EPKLAXEFEGDIXILHHPTQLAYKYQAMVHVGSVRQTATIVSMSKDHLRTGDKAVVRFRF IKNPXYLRPDTRLVFREGRTKXVGTVTRMIPHVGV-------------XXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX------------------------------------------- -------SQLYFVVVVTTEVPPLFVIEFLHRIVNTFEDYFTECTETTIKDNYVIVYELLD EMLDNGFPLATESNVLKELIRPPNILRTLTDTVTGKSTTMSDTLPTGQLSNVPWRRTGVK YTNNEAYFDVIEEIDVIIDKSGSTVFAEIQGYIDCLIKLSGMPDLTLSFVNPRLLDDVSF HPCVRFKRWENEKILSFVPPDGNFRLISYHIGAQNVVAIPIYLRHSISIREGAAGRLDIT IGPKQAMGKTVESVSVEIPFPKSILNVTLTASQGKYSFDPVTKVMTWDVGKIDPAKLPNI RGSINLQTGSPPPDANPTVTVHFVINQMAVSGIKVNRLDMYGEKYKPFKGVKYVTKAGRF QVRT-------------------------------------------------------- ------------------------------------------------KNLPTEVNVENL VTREGRQNVDVVEDEAEDQLRKERQVIEAIKRQLQTQIDQSFEQLCLLQEARQQILADLQ DKNIALDIDIEQYNLTEESPNISYKPDPTRVPKGSTTPQQWEDFSRYNKERAEAEMAKSR RLREANHHVMQQTDNDLATQQAAVDYALRKRIHEFERALDELNWQKQQTEEEIAEVEEEI RRLQDAIRAKINPMKLAQTRLENRTYRPNVELCRDNVQYGLTDEVKQLEATTKALEDKLK QAQHALHNLEQKLHRINESIQLKTNSLLLDKQCVNARDKLGS------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------EYSMNLIAKLPTIAAIIYRNLY RDGTSVGTVDTNKDWSANFVSQLGYENPQFTELMRLYLTIHSDHEGGNVSAHSCHLVGSA LSDPYLSFAAGMNGLAGPLHGLANQEVLIFLHNVKYTEAQLKEFVQNQLKSGQVIPGYGH AVLRVTDPRYSCQREFALKHLPNDPMFKLVSDLYKVVPEILGSVGKIKNPWPNVDAHSGV LLQHYGMKEMSFYTVLFGVSRALGCLSQLIWARALGFPLERPKS-----------MPFQA PQAEKCDVCTKSVYAAERMEAGGRIYHKMCFKCSVCKNSLKLNNYAQAEGILYCKTDYGK QVLAKNSQIDSLFVHRDTPENNADTPFEFTAENLKRAQHIIGNYPKGYERSAVMPLLDLA QRQHGWLPLTAMNYVADLLKMSRMNVYEVATFYTMYQREPVGKYHVQICTTTPCMLGGCG STVILDALKKKLGIEPGHTTADKMFTLHEVECLGACVNAPMVQINDDYYEDLTVKDINEI IDDLKAGKXPKAGPRSGQGHRFASEPAGGLTTLKTPPYGPGFKVQKDL------------ ------------------------------------------------------------ QKKLTLVFEYSDQDLKKYFDSCNGEIDPDIVKSFMYQLLRGLEFCHSHNVLHRDLKPQNL LINKNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIX AELANAGRPLFPGNDVEDQXKRNFQIAWYTTEERGLGVTQLPEYKPYP------------ ---------------------------------------NDSRFLTYSGPVAGVKYPLND ICDGWPLEYCEFHPNHEKAKEWIDKNLTDDMRDLYLKRQTRGGRGVVKLKQKQDEKRIAL SRACRGKRKYVTVVTGLTTYEIDLKVASKFFGSRFACGSSVTGDDEIVIQGDVKDDLLDV LLEKWPQIDEDSIEDLGDQKR--------------------------------------- --------------------------------------------LKAEDHRVLIYSQMTR MIDILEEYLWHRKHSYIRLDGSSKIADRRDMVADFQSRSDIFVFLLSTRAGGLGINLAAA DTVIFYDSDWNPTVDQQAMDRXHRLGQTKQVTVYRLICRGTIEERIVERAREKSEIQRMV ISGGNFAPDILKPKEVVSLLLDDDEMQRKMSIDMVPKEMRNLRACLLCSLIKTLEQFEYD GCENCEEYLHMKNNRDTVYECTSSSFDGIIAMMSPEDSWVAKWQRISRNQKGCYAISVTG RLPPGVINDLKSKGVVYRSRDTSMSRFVPYLSKEKEDELRRIANAIVAPGKGILAADEST ATIGKRLQNINVENNEANRMAYRQLLFTALSEHISGVILFHETLYQKGSDGQPLVNLLRS NGIIAGIKVDTGTVALAGSDGEVTTQGLDGLAERCAQYKKDGCDFAKWRCVLKISAHTPS LQSMIENANVLARYASICQQNGLVPIVEPEVLPDGDHDLYTAQRVTEQVLAFVYKALADH HIFLEGTLLKPNMVTAGMSCPKKYSPDEVALATVTALRRTVPPAVPGITFLSGGQSEEDA TVHLNAINRRPWALTFSYGRALQASVLAAWQGKAENVAAAQQELLKRAKADGLAAIGRYE GGISGAGGASLFVADHKYYIKTLPKVVRRRLKALKRLQAEVNKVEAKFYEEVHELEQKFA AQYEQYFIRRRDIVTASSEPTDAECDWPSDEEEDL-KAKIEDDENTKGVPDFWLTIFKNV DMLAEMVQPHDEPILRHLQDIQLKLKSGFVLEFIFEPNDYFTNPVLTKEYFIRFTVDPEN PLGYEGPDIVRCTGCKIDWKKGKNVTVRVVKKVQKHKNRGTKRTVTQTVKNDSFFNFFDP PKVEDNEPDEDTEALLTADFEIGHFLRENIIPRAVLYFTGEALDDEEEGDDENEDIILLK EGTDTSQGKPQLISNINACQAISDAVRTTLGPRGMDKLIVDDRGKASISNDGATIMKLLD VVHPAAKTLVEIAKSQDAEVGDGTTSVVLLASEFLKQCKPFIEEGVHPQIIARAFRRATT MAVQRIRDIAVHIKENPEQHRELLKKCAATALSSKLVAHQKDFFACMVVDAVMILDELLP LNMIGMKKVQGGALEDSLLVAGVAFKKTFSYAGFEMQPKRYQNPKIALLNIELELKAEKD NAEIRVESVEEYQAVVDAEWSILYNKLEKIHQSGAKVVLSKLPIGDVATQYFADRDMFCA GRVVEDDLKRTMQACGGSIQSTVTSLTLGTCELFEEQQIGGERYNFFTGCKKAKTCTIIM RGGTEQFIEETERSLHDAIMIVRRTIKNDAVVAGGGAIEMELSKYLRDYSRTVAGKEQLL IGSMAKALEIIPRQLCDNAGFDATNILNKLRQKHAGRWYGVDISSEDIADNYEACVWEPS VVKINALTAASEAACLILSVDETIKNPKSSPDAARGGRGRGRPMKGNNMIPNGHFHKDWQ RWVRGWFNQPARKQRRRDNRQKKALAIAPRPVAGPLRPIVHCPTFKYHARVRAGRGFTIE ELKAAGIRKREARTIGIAVDHRRRNKSMESLQQNVQRLKEYRAKLILFPKKASKPRKEDS SPEEVKLAVQLTKPLMPVRTIHKKEKARAITDAERKYSAFVALRQARAHARLAGKRAKKA KEAMPNIKIFSGTSHIELAQRICDRLGIELGKVITKKFSNQETSVEIGESVRGEDVFIIQ SGCGEVNDMIMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSPISAKLIANMLSTA GADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENIPEWRNSIIV----------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------LTCRFYEHRFPEIDDVVMVNVKSIAEMGAYVRLLEYNDIEG MILLSELSRRRIRSINKLIRIGRDECVVVIRVDKDKGYIDLSKRRVSAEEVIKCEEKFAK AKAVNSILRHVANLLDYESNEKLEDLYMKTAWMFDRKYGKPGASFEAFKHAVTNPEILNE CDIDDSTRDKLLENIKRRLTPQAVKIRSDIEVACYGYEGVDAVKSALKKGLSMSTEDMPI KINLIAPPLYVVTTNTLERVEGMARGQQKIQSQQKNAEKLAKMKSDQKKAAAAALVYMCS VCKTQMPDPKTYRQHFENKHPKNPLPEELQSV---------------------------- ------------------------------------------------------------ VDKCITAIDKTWHPEHFCCLMCGHKLGSEGFHEHDGQPYCQEDYFEHFAPKCGGCSRPIV ENFISALNRQWHPPCFVCTECRIPFGTGTFFEHEGMPYCETHFHAQRGSLCAGCHKPVTG RCITAMYRQ--------------------------------------------------- ------------------------------------------------------------ KTQQFRLHITALDFLAPYAKYKVWLKTSAEQQFLYGNHVLKSGIGRMTENIERYQGIVVY SMNDLPLGFGASAKSTADCRHADPMTIVVFHQADIGEYIRSEETLADQRKFFVGGNWKMN GTKSSIDEIIKFLNEKNPNTEVVVAPPAIYLSYVREKLIGVAAQNCYKAEKGAFTGENSA QAIKDVGCHWVVLGHSERRHVFHEPNELIGEKVAFALASGLNLIPCVGEKLEEREANKTE EVCFTQMKAADWQRVVIAYEPVWAIGTGKVATPAQAQEVHKSIRNWLEQNVNADVAKSVR ILYGGSVTADNCKELAQQPDVDGFLVGGASLKPEFINIINAR---------------KTF TAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEIISGEQLPKPDRGKMRIHKLSNVNKAL QFIESKGVRLVSIGSEEIVDGNLKMTLGMIWTIIVQNFHLSFKDGLAFCALIHRHRPELL DYNKLSKDNPLYNLNLAFDVAEKYLDIPRMLDAEDMVNSIKPDERSVMTYVSAYYHAFAG AQQAETAANRICKVLKINQENERLMEEYERMASDLLEWIRRTRPWLENRTTDNTVPGCRR KLAEFRDYCRAHKPPKVDEKAKLEATFNTLQTRLRLSNRPAYMPTEGKMVSDIANAWKGL EGAEKGFEDWLLAELQRLERLEHLAQKFKLKCDIHEAWARGKEDMLQAQDFKKCRLSDLK ALKQRHEAFEGDLATHQERVEQIAAIAHELNSLGYYDVKTVNSRCQKICDQWDLFGTLSQ QRRNALQEAEQILDKIDRLHQEFAKRAAPFMNWMDGAKEDLVDMFIVYTVEEIQRLVDAH ETFKLTMGEADKEFNSVIALVQEVHRICQQYGITSGYENPYS------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MTAVDPNNFGYVTFEAFLDFMTREATDTDTADQVMQSFRVLAGDKNYITADILRREL PPDQAEYCIRRMAPYNGRDSVPGALDYRSFSAALYGESDLNKLSIDQIDVNGKRVLIRVD FNVPMKNGKITNTQRIVAALPTVKYALEKGAKSVVLMSHLGRPDGKVVDKYSLKPVAEEV QKLLGRDVQFLTDCVGPEVEAACADPAVGTVILLENLRFHIEEEGKVTAEDGSKIKADPK KVDEFRASLSKLGDVYVNDAFGTAHRAHSSMVGCQLPQRASGFLLKKELAYFAKALENPD RPFLAIMGGAKVADKIQLIENMLDKVNEMIIGGGMAFTFLKVLHNMEIGKSLYDEEGSKI VQRLMDKAREKNVQIHLPVDFVTGDKFAEDATVGAATLESGIAADALGLDIGPKTAANFS SVVLRAKTIVWNGPPGVFEFENFSKGTKAVMDAIVQVTASGATTIIGGGDTATCCAKYNT EDKVSHVSTGGGASLELLEGKVLPGVDALSPAMSGIPPKSWQPPTVVLETSMGVVELELY WKHAPKTCCNFAELARRGYYSGLKFHRIIKEFMIQGGDPTGTGMGGASIYGKQFDDEITD ELKHTGAGILSMANSGPNTNGSQFFITLAPTQWLDGKHTIFGRVLRGMQVISRIGMVETD SDDRPVDDIKIMRRRSRSRSQDRKKGGGLTRKPYKYWDVPPAGYEHMTPMEYKALQFAIA GGGVTISRQARRLYVGNIPFGVTEDAMMDYFNNQMKMAGLAQAEGNAIISCQVNLDKNFA FLEFRSVDECTNALAFDGINFQGQLLKLRRPREYQALPGISENPSVGIVSTIVADTPNKI FIGCIPNYLNEDQVKELLSSFGQLRSFNLVMDTGTGLSKGFAFCEYLDQACAGLNGMQLG DKKLVVQRASVGKNPGTPVMMNMQIPGLSMDQVATEVLCLMNMILPEDLEDEEEYEDILE DVKEECSKYGYVKSIEIPRPIKGVEVPGIGKIYVEFGAISECQKAQQGLAGRKFANRVVV SSFFDVEKYHRREFFIPLFDRILVERFAPELKTKGGVLLPEKSQGKVLEATVLAVGPGSR NDKGDHIPPSVRVGEKVLLPEYGGTKINFDDKEYFIFRDGDILGKFEXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMAEDAIAKAGLYFDELNK IRVLDPEVATQTNELKDECKDFLDKMTQFQKIVGGFIQHIDTVSKEVEKEKLKAIASRNQ LKSISKQREAQQQQLLALILEKRMQLERLRIQYEALSKEEREQTEFVEQLILQKRRRSRE RDRKDRFRGRSSEKPPRDLTPEERDARTVFCMQLAARIRPRDLEEFFSSVGKVHDVRLIL DNKSHRSKGIAYVEFREVESVPLALGLSGQRLLGVPIIVQPSHAERNRIAATGGPMRLYV GSLHYNITEDMIRGIFEPFGKIDDLKLMKDHQTGRSAGYGFITYRNAEDAKKAMDQLNGF EVAGRPMKVGHVTDHSVEGSYYDIDDMDRAGFGLGATGRIQLMAKLAEGTGMQLPQAAAA VLQQAPVQAIPPIATQCFMLSNMFDARTTNPRWEAELIDDVINECNNYGGVVHIFVDRDS EQGNVYVKCPSIAAAVSSVNGLHGRYYAGKLMVAAYVPLPNYHQLFPDSARAVNFVLPSG SEDRDEVSPSPPQPPKRRPRRNAVSAEVYTEEDAASYXKKVVPKDYKTMAALSKAITKNV LFLHLDDNERSDIFDAMFAXNRHRGEIIITQGDEGDNFYVIDHGEVDIYVNGEHVSTIGE GGSFGELALIYDTPRAATVKAKTDVKLWGIDRDSYRRIXMGSTIRKRKMYEEFLSIRSIL ESLDKWERLTVADALEPVHFEDGQEIVRQGDPGEDFFIITEGIAVVLQRRSDNEEPVEVG KLGSSDYFGEIALLLDRPRAATIVARGALKCVKMDRTRFERVLGPCSDILKRTL------ -----------------------ALAHVQTTHNVVMYQNIHKQLVDAINASVPALDVQWS ESTQKRAALKLEKLDIDLKNYKSNSIKESIRRGHDDLGDHYLDCGDLANALKCYSRARDY CTTARHLVNMCLNVIKVSIYLQNWTHVTTYVSKAEMTPFLMENKEGNQVVVTKLNVAAGL GELMCGKYKAAARLFLTANIDHCNFPELVSPNNVATYGTLCALATFDRQEIQRLVLNSSS FKLFLELEPQLREIVYKLHDSKYASSLKLLDEMKDSFILDLYLASHVESLYSQIRSRALC QYFSPYHSADMHKMAVAFNTTVAALEEELMQLILDGKISARIDSHNKVLYVKDVDQRSIT FAKALEMGEEYQMRSKALVLRAAVVKSQIQVKSAAREGSQESSM-------------DHV MSKSRDIADDILRYGRKSLPHIARFCLVSTYIDDGLRMWFDWTPQAQYMNYTWNCGWFLA TLFVIVNLIGQLSASVLVLSQKHATIACGMLFSITGLQIVAYNTLWELKFFMRNLAVAGG VVLLLADSWSEGRQLFAGLPVGEDKSRKPYMLLSGRVLLVLMFLTLLDFNMDLFSLLTDL IGVALVVLIALGFKTRVASLILAAWLTLSN------------------------------ -----------------------RQTVTLIPGDGVGPELMSSVRAVFSAAGVPVDFEEVI ASKNKVILKGIISSPLQTLNMRIRRSLDLFANVVRVKSLAGFPTRHGDLDFVIIRESTEG EYSALEHESVPGVVESLKIITRANSSRIAQFAFDYAIKXNRKKVTAVHKANIMKLSDGLF LKCCQEVAQNYPSIKFDNMIIDNTCMQMVSKPQQFDVMVMPNLYGNIVDNLAAGLVGGAG VVPGESHGTDIVAFEPG-HDTRCGSAGRNMANPTA------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------TPEYMFQCQSSVLSACFAXFHPNLVIGGTYSGQVVLWDTRTNRRTPA QRTPLSNVGHTHPVYCVGVIGTANAHNLASISTDGKMCFWSLDMLATPQETLELQYRQAK VAAICYSFFAGDPNSFVIGAEDGIAYSGARHGARAGVSDTFEGHCGPVTGIDCHSVGGPL ------------------------------------------------------------ ------------------------------------------------------------ ------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRSIVLTGFGGVRMVKVQNRPKPIE GEVLIRVKACGLNFTDLMVRQGVIDNPPKTPFTMGFECAGEVEALGENSNRFEIGDRVLA VTKAWAEHVAFVYKIPTSMSYEEGAALFMNYVTAYILLFELGNLRANQSVLVHSAGGGVG MAVAQLCKTVSGVTVFGTASPKHDAIRSS-FDHVYDH-TVDYVQEIRKVTPEGVNVVLDS LCGEDTNRGIAVLKPLGKYILFGSSNVVTGETKSFFSFAKSWWQMDKISPIKLYDENKTI AGFHLRQLLIVDTLFQLYNEGKIKPVDRFRWAY--------------------------S RRQTPSEFLKKIVGKPVVVKLNSGADYRGILSCLDGFMNIALEQTEEYHGGQLKAKYGDA FIRGNNVLYISTQKQ--MSVTQSALLLQRQLAELNKNPVEGFSAGLIDDSDIYRWEVLII GPPDTYFEGGFFKAHLTFSKDYPQKPPKMKFITEIWHPNISKXGDVCISILHDPGEDXYG YERPEXRWLPIHTVETIMVSVISMLADPNDESPANLDAAKEWRECREDFKRKV------- ----------AAKQTLVDFGQYVGQCLPKYVQKVQVTNGDELEIMIHPDGVVPVLTFLKD HTNAQFTNIADLCALDVPTRKFRFELVYNLLSVRYGQRIRVKTYTDELTPVQSCSSVFHG ANWYEREVWDMYGVFFANHPDLRRILTDYGFEGHPFRKDFPLVGYVEVRYDDEVKRVVAE PVEMIQEWRKFDLGNPWETFPAFREP---------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --GPGMVIDDELKNTIRSHHDIEKDNCKYMKKAMKHYESLAARAANNGHAVDIYSCSLDQ TGLHEMKYLPSNTGGHMVMGDSFNTSXFKQTFQRVFSKDLKNEFRMAFSGNVEXKTSREL KVQGCIGSCISLNVGPSVSETELGISGTTRWRMCSIYPNSTYAFYFEVVNQHNAPXHKEV GGYIQFITQYQHSRGQRRVRVTTIARTWADATINIQHIAAGFDQEASAVLMARIAVFRAE TDDGPDVLRWLDRMLIRLCQKFGEYNKDDPSSFRFSEQFTMYPQFMFHLRRSQFLQVFNN SPDETSYYRHMLLVEDLNQSLVMIQPILYAYSFNGPPEPVLLDTSSIMPDRILLMDTFFH IVIYYGETMTQWRRAGYQDMPEYENFKQLLQAPVDDAQEILQTRFPMPRYIDTEHRGSQA RFLLSKVNPSTTHNNMYSEGAGMVLTDDVSLQVFMDHLKKLAVSSST------------- --------------MSAACQKKCVPPKYKEAELSKGESVCLDRCVAKYMEIHDRIGKKLT SVTMADQETAQKLQASQSTGIIHKVIMVGSGGVGKSALTLQYMYDEFVEDYEPTKADSYR KKVILDGEEVQIDILDDYAAIRDNYFRSGEGFLCVFSITETESFQSTIEFRDHIVRVRGD DRAPFILVGNKADLESKRKIATEEAQSRARQWNVPYVETSAKTRANVDKIFYELMRLIRT RKEQNKKLNRKCNILKLYTGLREVVTEHLVNKVRSDVVDSLNNNFLQTLNNAWNDHQTSM VMIRDILMYMDRVYVQQNSVDNVYNLGLMIFRDHIIRHPLIHSHLRETLLTMIARERRGE VVDRGAVKNACQMLMTLGIESRTVYEEDFEKPFLQQSAEFYRLESEKFLAENSASVYINK VEARINEEAERAKHYLDKPTEEHIVKVLEDELIKR------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------FTSKLEGMFKD MNVXNTIMDEFKQHVQHGANLHGVELFVRVLTTGFWPFQSAMSXCNIPAAPRMAFDAFRX FYLGKHSGRQLSLQPQHGSADLNAXFYGPRRSADAAGKGMRKHIIQVSTYHMVILMLFNN RDSWTYEEIRNETDIPERDLMRAIQSLALGKITQRVLSKDPKTKDIENDHVFTVNDQFLP KLFRVKIQTVDXKGDTEPERXETRNKVDEDRKHEIEAAIVRIMKAR-------------- ----------------------------------------DRISVFPSRMAQTLMKARLK GAQKGHSLLKKKADALTVRFRQILKKIIEAKILMGDVMKEAAFSLAEAKFAMGDFNHLVL QNANKAQLKVKSKKDNVAGVSLPIFESYQDGSDSYEYTGLARGGQQIDRLKKNYAKAIDL LVQLASLQTSFVTLDEVIKITNRRVNAIEHVIIPRIERTLDYITTELDEREREEFYRMKK IQRKKGEMR--------------PLRILITGAAGQIAYSLLYSVAKGDVFGPTQPVSLVL LDIEAMMGVLTGVVMEMTDCALPLLREVVSTADIASAFKDIDVAILVGAMPRREGMERKD LLKANVRIFKQQGEALNQYAKKNVKVVVVGNPANTNALICQMYAPSIPKENFTCLTRLDQ NRAQSQIAARQDVHNVIIWGNHSSTQFPDVAHATVVTEAVKDAAWLHGDFISVVQKRGAA VIAARKLSSAMSAAKAICDHMHDWWFGTKTGRWVSMGVPSDGYGIEPGLIYSFPVAIDHT YYIVQGLSINDFARQKLDATKQELVEERDDALKAC-----------HFRVGKKIGSGNFG ELRLGKNLCTNEYVAIKLEPIRCRAPQLHLEYRFYKQLGQTEVVPNVYHFGPCGKYNALV IELLSSTLEDLFNICDRRFSLKTVLMLATQLISRLEYVHSRRLVYRDVKPENXLIGRRSA RRSFLVHIVDFGLAKEYIDPVTHKHIPYRENKNLTGTARYMSIGTHLGREQSRRDDLESL GHMLMYFLRGSLPWQGLKADTIKER----------------------------------- ------------------------------------------------------------ --------------------------------FNNVNLDPLTETYGLAFYLQYLAHWPEY FQVAESPSGHVMGYIMGKAEGQGENWHGHVTALTVAPEFRRLGLAAKLMHYLEDISEKKK CYFVDLFVRVSNNVAVDMYKHLGYIVYRKVLDYYSGDTDEDAFDMRKALSMDVEKKSVIP LSRDFRPEEV-------------------------------------------------- ---------------------------------------------------FDQYRDMYF EGGVSSVYLWDLDHGFAGVILIKKAGDGSNKIKGCWDSIHVVEVQEKSSGRSAHYKLTST AMLWLQTSKAASGTMNLGGSLTRQVTADSNVSEASPHIANIGRMVEEMENKIRNTLNDIY FGKTKDIVNGLRSTIPMQRDNLRFDLAAALKNRGQ--GDMDDVDQELEEVPERENVEVLP ADQRVDDDKRTTTPYMTKYERARVLGTRALQIAMCAPVM--------------------- --------------------------PQQALKEIFMKPASDTPFAVGKAFLAGSSVVALG ALCYYGMGLSNEVGSVDRAVLWSDTVKHRIRDTYTYFGGSLIITAISRNVRIMNFLARGS WVSLIGTVVAMMGTGMLCQALPYQEGAKQMAWMLHSGVIGMVIAPLTLLGGPLMVRAACY TAGIVGGLSTLAVCAPSDKFLYMGGPLAMGLGVVFISSIGTWFLPATSAIGAGLYSIAMY GGLALFGAFLLYDTQKIIHRAENHPIYASVPFDPINNSVGIYLDTVNIFIRVAMLLAGGG NRRKMEIVYVYTKQRKEFGRQCNFSDRPAELHCDIVPDGSLSANFVERNPVDMGVQCVQE MSEHEVNTERFETEMRGVNHTEGGWPKDVNPQEIEQVIRYRKKI------IMGMFRSTHV LTHHLQNN---------------------------KYFRDPNEIKRTAAHISWFPDGPRK LAIAYSRLEFQSASSTSMESYIWDIENPNKPEMTLKPSSPLVCVEYNPKDAHILIGGQYN GQIVYWDTRKSSQPVDMTPVENSHRDPAYKVIWITSKTGTECFSASSDGQVFWWDTRKIS EPTEVMYLDTTKKQDPTKAQGAMCLEYEPTIPTKFMAGTEQGNIIACNRKAKRLLXKIIA VYPGHIGPVYALQRNPFFPKNFLSIGDWTARIWSEDIRESSIMWTKYHMSYLTDGCWNPI RPAVFYTTKMDGTLDVWDIMYKQNDPILSLQVCDEPLHSIRAHDQGCLLATGSHNGTTTL LELSSGLSTLQRNEKAVITAMFERETRREKILEARHREQKLKERTKSQWDKLVSQVEPIA NPLASRKLAKRIYKVIKKALRRGVREVQKFIRKGDKGIVVLAGNTSPVDVICHVPVMCED SSLPYCYVPSKEDLGTMCCSRRPTCALMIKSHADYKDAYDELWQDIKSLP---------- ------------------------------------------------------------ ------------KLKEIDDSIADAEKNQGEMEIRDFMLKKAEYYSIIGAKDLALAQFRKT GERTLTLGYRLDMVFHEIRIGLFHMDHDLIKRSLEKAQALIDEGGDWDRRNRLKVYRGTY CMAVRDFKTAAKLFLDTVATFTSYELMDYKTFVKYTVYCSMIALSRPDLREKVIKGSEIL EVLYSLPNTREYLFSLYNCHYADFFVKLAEVEQEMKQDRYLSAHYRYYAREMRILAYAQL LESYSSLTLDYMSRVFGVSISFIDQELSRFIAAGRLHCKIDKVGGIVETNRPDSKNWQYQ EMIKRGDILLNRVQKLSRVINI-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------EGLFKMAGCMGSGALIGAVMXKRMEVTDLPQMVALFHSLVGAAAVITC LANFMAEQPHFDTDPAANVVKTSLFLGTYIGGVTFTGSLIAFGKLQGLLNSAPLLLPGRH ALNAGMFAGNIAALVPYMLSNDTLGLSMLGVTTGLSSVMGITLTAAIGGADMPVVITVLN SYSGWALCAEGFMLNNNLMTIVGALIGSSGAILSYIMCKAMNRSLPNVILGGYGTSSYAG GQAMKIEGTHKEIQVPDTVELMTEAKNILIVPGYGLCVAKAQYPIAEMVSLLKSKGKNVK FGIHPVAGRMPGQLNVLLAEAGVPYDIVHEMDEVNPEITDFDLTLVIGANDTVNSAAEED PNSIIAGMPVIRVWLTKQVIVMKRTLGVGYAAVDNPIFFKENTHMLLGDAKKTCDALLTK VKMAKPPAIPGVPIGLEYLTQIDQLLVHQQVEIFEVLTGIETCNRYQIKNTVGQQVYFAG EESDSCMRQCCGPQRSFVMHITDNFGQEVIRVRRHFKCVFGCNCCAACAMEISIEAPLGQ TIGYVRQRCMQPIYGVEDAILMIHGPSCICPGPCDTGDQEFVITSHEIGKISKQWSGFLQ EYFTDADNFGITFPMDLDVHVKALLLGAVFLIDFMYYESNE-XXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMN RSEGLVQRRNVSHRDDDAHSKETRLTLMEEILLLGLKDREGYTSFWNDCISSGLRGCILI ELALHGRIEXEKGGLNRRPLLDRKVLLKSDSPTGDVLLDEALKHIKETSTGESVPTWIEY LSGETWNPMKLKYQLRNVRERLAKXLWRKGVCTTEKXNFVLFDMTTHPVNDSSAKQRLIN RIQXAVLSRWTNDANRFERRXSALIYLAHASDRXE------------------------- ------------------------KKISEATEENCEVCVKFLTKFIDSLDKIENEFRKFC KKTKGDDNRFCYYVGGLEESATGMLSEMSKPVSWSMPADKICMKLYRKDEQICDLRYEKT FDYSKTDFKKLKVHELKQILSDWGEQCRGCSEKSDYVRLVEELLPKHVPDAAXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXMPKVVSRSVVCTDVKDKEEYQEEKPLNVYYCVCGQMSLILDCPIE KLPLRQRDNARVIDSAKHAHRITCEPDETVFLKRPEGIEKQYRFKCRKCSLWLYYRHRNQ ITFLVQNALVKAGDAKTDIYTQIAATPKVMVTKHTKNMGKFSSVTVSTVDEEEDEIEAKE IADSYAANARVIEKQLLRKGFSKRKLMEQAEDEIKKSRPKGTLID-----------QLSR NYADMAFTFASPASVNVKQIDVPSFSGHFGILPSHVPIIAVLKPGVVTVHEQEGANKRYF VSSGSVTVNDDSSVQILAEEACLVEQLDAQAVRDGAAKAAQDLSTEVAKAEAQIAVECYE AMQKAVECKYFVTELTNRLAESAKSKEIIETGHGLEKKKRFKYLTSELRLTEALHEPHIC ENILHYNVHAERKGSLRYAKGMSETMQTLHGLVNKGVQVELGIPYELWDKPSAEVSKMHR ACFLFAEKHEDDIEEWYYHLQENLLQYLCAERYLKGKDQLFAPTDVTSEADVKAALVVKE KFGQLDIAVNCAGIGIAAVTYNANKDRVHSLEDFLTVIKVNLGGSFNVIRLSAQLMAQNK PTEGGQRGVIINTASVAAFDGQRGQAAYSASKGGIVGMTLPIARDLSNIGIRVNTIAPGL FDTPLLAGLPEKVRAYLASTIPFPQRLGLPDEYAHIAQSIVENPMVNGEVIRVDGALR-R NFSFRVHGRNTDAKQQLSRDYPVIDHEYDAVVVGAGGAGLRAAFGLASVGFKTACITKLF PTRSHTVAAQGGVNAALGNAEDDKWQWHFYDTVKGSDWLGDQDAIHYMCEEAPKAVIELE NIGMPFSRMDNGKIYQRAFGGQSLDFGRGGQAHRACCVADRTGHSMLHTLYGRSLKYDAD YFIEYFATDLIMEDGQCKGVMALSMEDGNLHRFRANNTVLATGGFGRCYFSCTGAHTCTG DGNALVARAGMSNQDMEFVQFHPTGIYGAGCLITEGVRGEGGYLVNSKGERFMERYAPNA KDLASRDVVSRAMTVEIREGRGCGKDHDYIHLTMSHLPPEQLHARLPGISETAMIFAGVD VTREPIPVLPTVHYNMGGTPTNYLGQVIQYNGKDQVVPGLYGAGESASVSVHGANRLGAN SLLDLVVFGRACAMTIAKTNKPGDPVPKVKDNAGEVSVANIDKLRHANGSVTTAQLRLKM QKVMQDHAAVFRDGPTLKAGCEKISALWKDLNLKVADRGMIWNSDLVETLELQNLMLNSA MIVYGAENRKESRGAHAREDFPNRIDELDYSKPLDGQQKNQLXQHWRKHTLAHVDPETGK VSLSYRPVIDTVLDAKKVDYVPPKVRTY---MTQDEILRQTKTVVQGLDSLKTEHAQLLA SLRAIGGSGSKSDAHDVDDRIAVVSKSLEQLDMGIGEAQMMIALANHMQYLESEKQKLRS QVRRLVQENTWLRDELAHTQQKLQLSEQKCASLEEEKKHLEFINEMKKYDTDSALGFPDD EDDQHPDAVGPASSAGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHD HPDVATMLNILALVYRDQGKYKEAATLLNDALQIREXTLGPDDPAVAATLNNLAVLYGKR GKYKEAEPMCKRALSIREKVLGKDHPDVAKQLNNLALLCQNQNKYDEVEKHYKRALDIYI QKLGIDDPNVAKTKNNLASAYLKQGKYRDKIASRWDSEAEKELISWFKQLINSGMHKVEK TLRNGQHLVKLIQVIPARKMVLKYNTMEAPFKRMENIQLFLTFCENYGVPKTNLFQTVDL YEGTNMPQVLSCLQTLGTECQRNGFQGPVIGPKPTEKNIREFSDEQLRAGEFQAGSNKGA NQMIGGVRHVADIKADDMSREGAAVIGLQAGNKGASQSGMSIGGVRHVADIKVDEMSREG QAVIGLQAGYNKGATQSGMSIGGVRHVADIRADDMSRDGSTIIGLQAGTNKGASQAGMSI GGIRHAADIRADAMSESNAVISLQAGYNKGATQSGMTIGSVRHVADIRADDVDGANVIGL QMGTNKLATQSGMTMGGVRHVGDIATEPMSSQGVINLQYGSTDGATQAGMTTGGRRDVMP ETTSFGIDPVTDHSWNKDRNQIAIPNNNEVQIHQLKWTQTETLSEHGQRVTSIDWAPNSN LIVTCGADRNAYVWPTLVVLRINRAATCVRWSPLENKFAVASGARMISVCYFEKENDWWI SKQIKKPIKSTVTCLDWHPNNSLLACGSTDFKARVFSGYVKEVDEKPAATAWGSKMPFAN LMAEFSSGGGWVHGISFSASGDRLVWVGHDSSISIVDATLKTDFLPFSAVTWITDNSVVA AGFECAPMLYAFNGNSINFVSKLDGKKVSAMERFKNLDAKAASLGTVHQNTVTQVKIHSG TKSRCTKFSTTGVDGQLVIWDVKKDVEGYVGFASLPNQIYRKSVKRGFEFTLMVVGESGL GKSTLLNSMFLTDIYSNDYPGPSVRSRKTVQVETTNVVLKEGGVQLRLTIVDTPGFGESV DNSSCWQPIVNFLESKYEEYMNAEARINRRVVPDTRVHCCLYFISPNGHGLKALDIEVMK SLHDKVNIIPIIAKADTMTPEECQDFKKTVLNEIIQNKICIYEFIDEEENRSMKKLKDRV PFAVVGSNTVVESQGKRVRGRIYPWGTVEVENLEHNDFVALRNMLLRVHMHDLKDVTNNV HYENFRYRNLASVSKSPLVQMDEERREHLQKMKKMEAEMEQVFEMKVKEKMQKLKDSEAD LQRRAEQMKKGLEQQERELEDKYKQFEAERDAWDEQNR---------------------- ---------------------------RNTNKLLDEVSFSEKIYKLHDDMACSVAGITSD ANVLTSQLRLFAQRHQLQYGEPIPCEQLVATLCDIKQAYTQFGGKRPFGVSILYIGWDKH YGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQEYKEGETTLQQALDLSIKVLSKTLD TNKLSADKVEIATLTRENNVTRIRILPTSELEVLVKKFEEEEAKAEAEKKK--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------DALLQRRNGLYDKAARRRAALEESYKLQMFERDYDETKIWINEKLKAASDEG YLDPTNLQGKLQKHENFASELQANQARIEAVTQSGEELINEGHPSKDHIRELINELQLLW QRLAEQSDRKGSKLKEANDQQQFNRNIEDIEVWLGEIEGQLMSEDYGKDLTSVQNLQKKH ALLESDVASRQDRIDAIAQAADQFVAAGHFDADNIKAKQLQLADRFKALHEPMQARRQKL RDALRLQQFYRDVEDEEDWIREKEPIAASANRGRDLIGVQNLMKKHHALLAELTGHEGRI TAVCGQGDQMVKEGHFAGDEITRKTSELQEKWNALKEKADKRRVDLDDSLQAQQYFADAN EADSWMREKEPIVGNTDCGKDEDSAEALLKKHEALMSDLEAYRSVIDGLKDQAQGCKQQE SPQIDNIGKECVVALYDYQEKSPREVSMKKGDILTLLNSSNKDWWKVEVNDRQGFVPAAY VKKIDSSLTASQSNLADEYTISVRQQQIDSQYASLLDLGRQRKEKLEESCKAYQLVREAG ELAQWIADKETVALSEEVGDDLEQVEGVQRKFDDFQKDLKANEARLIELNTVAERLTAMG QTEAAEKIRIQIEDLNQRWAALQQCTQERAQTLGSAQEVQRYHRDADETKDWIEEKEETL KSTDFGHDLATVQRLQRKHEGLERDLAAIGEKVKELDETAKRLMQTHPDQAQSIYDHQRE INDRWNSLTQKADARKAKLLDSYDLQRFLSDFRDLTSWIKSMMALVSLDELAKDVTGAEA LLERHKEHQMEIDARAGTFQAFEMFGHQLLQNGHYASDEVKAKLEELAEARQNLEKAWIA RRAKLDQCLELQLFNRDCEQAETWMAAREASL-DEGDGADSVEALLKKHEDFDRAIAAQE EKIAAIQNLAEQLKSNEHYDAAGIDHRQDEVLDRWNKLKENLLANRERLGEAQSLQQFSR DVDEMEIWITEKLQTALDESYKDPSNIQAKHQKHQAFESELAANADRIQAVLRMGEKLID KEQCAGSEDAVRERLNKLMDEWTYLTRKSSEKGEKLKEANRQRMYTAAVKDLEFWLGEVE HMLEGEDYGKDLATVQNLVQKHKLLEADISTHDDRVKDLNDRADAFIDSGMWDTENIKEK KQSINERYERVRTLAAHRRARLNEAQTLQQFLRDIDDEEAWIKEKKLLVSSDDYGRDLTG VQNLRKKHKRLEAELSSHEPAIQAVQDTGEKLMAESNLMTDEIQARLQQLAKNWDELRNM AAERSQRLDESLTYQQFAASIEEEEAWIMEKQHLLSGDDYGDTLAAVQGLLKKHGAFETD FKVHEDRCTEINNEGDKLIA-GNHNADNIRQRCQLLREKLDSLQRAADQRKAKLIDNSAF LQFIWKTDVVESWIADKEAHVRSDDYGRDLSSVQTLLTKQETFDAGLQAFEKEGIQTVTA LKDQLVAAQHAQTPAIEKRYKDVIDRWQRLLADAEARKKRLLRLQEQYRQVEDLYLTFAK KASAFNSWFENAEEDLTDPVRCNSVEEIKALREAHDQFKASLSAAEADFNQLAQLDKQIK SFNVGPNPYTWFTMEALEDTWKNLQRIIRDRDEELVTEQRRQEDNDAMRKQYAVVANAFH QWLTDTRAAMMEGTGTLENQLEATKRKSAEVKAQRAQLTKVEQLSAALEDRLILDNRYTE HSTVGLAQQWDQLDQLCMRMQHNLEQQIQACNQSGVSEDSLREFSMMFKHFDKDRSGRLD HQEFKSCLRALGYDLPMVEEGQRDPDFETILDMVDPNRDGFVSLQEYMAFMISRETENVQ SSREVIEAFKALTTAEKPYITANELFANLTKEQAEYCISRMKPYKDSSGRTVLDAYDYVS FTNELFIN---------------------------------------GTFCLKVTRQSPG WFGWIKQTRRCGSRSDTGVAWGCRWVYEDNGVWKETCYCDDRDGCNGSVLIDKDDSENTQ LVSEYVNDIYHYLRQLEIQEVTGRMRGILIDWLVQVHLRFHLLQETLFLAVAIIDRYLQV NVAKTRLQLVGVAAMWIAAKYEEMYAPEVADFVYITDNAYTKSDVRQMECQILKT----- ----------------------HTLAKYLMELTVVEYDLAHICPSLTAAASLCLAMKLVC WTPTLVYYPXYEESKLEPMMCRLCQLVLRKLTAVKTKY---------------------- ------------------------VHLGSLDETLIIFXSLLTGSFVEFSKRNPNVALSYG LCTKVSIFDVADSRYFFKDLERYDVVHVDDVTMEDCEFELCGYDFSTDNFSMSAPPTAVS SSTVTGSSEWHRKLSLRYQRIREIYNNYSSDLPGLFGSEASERWSDLRSEIDDYTDSWLS LANQVLEVVQSRPAHVNVLVTTTHLVPAVAKLLLFGLGSTFSIDNIYNASKAGKESCFDR IHSRFGDSCNYLVIG-------------------------------------RTALSVSG ARTTGQSVRTQNVMAACSIANIVKSSLGPVGLDKMMVDDVGDVTITNDGATILKMLEVEH PAAKVLVELAQLQDEEVGDGTTSVVIIAAELLKNADELVKTKIHPTSVISGYRLACKEAC RYVQDNLTISVDELGRDCIVNAAKTSMSSKIIGPDADFFANMVVDAANAVRVSDGKGGHR YPIKAVNVLKAHGRSSRESILVSGYALNCTIASQALPKKIVGAKVACLDFSLNKAKMKLG VQVLIDDPTKLEGIRQRESDITKERIQKILATGANVILTTGGIDDLCLKYFVEAGAMAVR RCKKVDLRRIAKATGAQLVATMANLEGEETFESSMLGQADEVVQERICDDELILIKGPKA RTAASLILRGANDFMCDEMERSVHDALCVVKRVLESKTVVPGGGAVEAALSIYLENFASS LSSREQLAIAEFANSLLVIPKQLTVNAAHDSTDLVAKLRAFHNTAQTKSDMRDLRWVGLD LTEGVVRDNKKAGVLEPAISKIKSLKFATEAAITILRIDDMIKMFPEEKKGRSYEDACNA GDFENDNARLLASKNILNQYMVENKDLTVLYEIYNVGGSSALEATLSDKSFPDTDFEVIH GNLEVSWERIGPGNNVSHVVILRPKKSGYFNFTSADLHYLASETEHQYAYTSAPGEGGIV SFKDYDRKFSSHVLDWAVFAIMTLPSLSIPFLLWHGSRSKYE------------------ ------------------------------------------------------------ ----------------------------------------------------TYLKVARL YLEDEDPVQAEAYINRASLLQAESGREDLQILYKACYARVLDFRRKFIEAAQRYNELSFK SIISEEERMTALRNALICTILASAGQQRSRMLATLFKDERCQQLPVYGILEKMYLDRIIR SSELHDFAGMLQTHQRAITSDGSTILDRAVIEHNLLSASKLYNNISFAELGALLEIQPRK AEKIASQMITEGRLNGCIDQIDSIVHFEVQEALPTWDRQIQSLCVQVNSIIERISSTAPD WLAQTIDQQMTMKLTENVVKNFLVAKIFRENTDRINSVDYSANGETLISSSDDDSIIIYD CQAGTPKRTLNSKKYGVDLIRYTHAPNTAIHSSTKVDDTIRYLSLHDNKYIRYFQGHTKK VVTLCMSPVDDTFLSGSLDKTIRLWDLRSPNCQGLMNLPGRPVAAFDPEGLIFAAGISSE SLKLYDLRSFDKGPFATFKMQQDKDCDWTGLKFSPDGKLILISTNGQVIRLIDAFQGTPL QTFMGHVNQKGIPLEASFSPDSQFVFTGSTDGKIHCWNTETGNKVVILNGEHTGPVQCVQ FNPKYMMLASACTNMAFWLPQVDEEYLVVEARGKDNQVGLVQLNRPKALNALCDGLMAEL AKVLDAFEVDTKIKCVVLTGSERSFAAGADIKEMKDRQFKDVYKGSFLSHWSRVSSFTKP IIAAVNGHALGGGCELAMMCDIIYAGEKAQFGQPEISIGTIPGSGGTQRLTRAIGKSKTM EMVLSGKPIPAQEAYVAGLVSKVFPPEKVVDKAVELAETIAAHSPIVVQMAKEAVNTSFE VTLSEGMHVEKRLFHQTFATHDRREGMTAFIEKRPPKFID >Pseudopolydora_vexillosa XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXX-LNVARQFQTSAVSRDIDQAAKYIGAGAATA GAAGSGAGIGTVFGSLCIAYARNPSLKQQIFSYAILGFALSEAMGLFCLMMAFLILLALM SHYKE-GKAPESTIHRIRITLTSRNVKSLEKVCADLIRGAKDKQLKVKGPVRMPTKTLRI TTRKTPCGEGSKTWDRYQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADMDQVM QYFEPAKQFTKDSIRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNII VMATQMSKKKKFVADGVFKAELNEYFTRELAEDGYSGVEVRVTPTRTEIIILATRTQKVL GEKGRRIRELTSVVQKRFNFPEGTVELYAEKVATRGLCAIAQAESLRYKLIGGLAVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPVNDYIDTAVRHVLLRQ GVLGIKVKIMLPWDPSGKMGPKRPLPDHVSIVEPKEETRIETPYSEQKGGKXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------------- --------------------------------------------RVQLIKNGKKITAFVP RDGCLNYIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVASVSLLALYKEKKERPR---- -TIRTRKFMSNRLLCRRQMIVDVLHPGRATVSKTDVRERLARMYKTTPDVIFAFGFRTNF GGGKTTGFGLIYDSLDFAKKFEPKHRLARHGARKQRKERKNRQKKVRGTKKAKIG-XXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XX---VFASLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVGEAREELMRMLAEDELRD AVLLVFANKQDLPNAMNAAEITDKLGLHSLRQRSWYIQATCATSGDGLYXGLDWLSNQLK NXKMPLAKDLLNPTLEDEKRKCKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRRKQHMVRMNVLADALKSICNAEKRGKRQVLIRPCSKV IVRFLSVMMKHGYIGEFEIVDDHRAGKIVVNLTGRLNKCGVISPRFDIAIRDLEKWTTNL LPSRQFGYIVLTTSGGIMDHEEARRKHLGGKILGFFFXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXX-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------GHQGYLNCVTMSPDGSLCASGGKDGQAMLWD LNEGKHLYTLDGGDIINALTFSPNRYWLCAATGPSIKIWDLEG----------------- ------------------------------------------------------------ ----------------------------------------AMRDLYMKNGQGFLLVYSIT AQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKLARQWNCAFLETSAKSK INVNEIFYDLVRQINRKNPDTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------ -----KPIMCKLKWGMEYKGYLVSVDGYMNLQLANTEEYIDGALSGNLGEVLIRCNNVLY IRGVEEEDEEGEMKEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMDDFQSGEETAFVVDEVS NIIKESIEGAIGGNAYQHNKVNQWTSNVVEQCLNHLTKLGKPFKYIVTC----------- ------------------------------------------------------------ ----------------------------------VISVPKPQLPQYRKIQSRLVRELEKK FSGKHVVIIAQRTILPKPTRKLHSKSKQKRPRSRTLTAVHEAILDDLCYPAEIVGKRIRV RLDGSRLIKVHLDKSQQTNIEHKLDTFTSVYKKLTGKEVHFEFP---------------- ---------------------------VADGKIKTLEEIYVRSLRIKEPEIVDKLLEATL KDEVLXIMPVQKQTTAGQRTRFKXFVALGDGNGHLGLGVKCSKEVATSIRGALIAAKLNL IPVRRGYWGNKLGSPHTVPIKTTGQCGGSTVRLIPAPRGTGLVAAPTPKKLLAMAGVEDC YTSSRGQTATLGNFA--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------CNNKNPHSIGLMWYLLAREVLRLRG TISREVPWDVMVDLFFYRDPEEAEKEAAAGGFGAPA-AAPAP-ATDDWSAADTGDWAAAA PGNEWGG-----SLSGSRRKQRCRHFNAPSHIRRKIMSAPLSKELKTKYSVRAIPIRKDD EVQVVRGHYKGQQVGKVVQVYRKKFVIHVERIQREKANGASVHVGIHPSKVVITKLKMDR DRKKILDRKAKARQ-GKHTEESIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------------------- ----------------------------------GIPRIRWFGEREYNVLVIDLLGPSLE DLFNFCGRKFSLKXVLMLADQMIGRIEYLHNKNFIHRDXKPDNFLMVSGQHCNKVFVVDY GLAKKYRDSRTRAHIPYREDKSLTGTARYASINAHLGIEQSRRDDMESLGYVFMYFLRGS LPWQGLKAGNKKQKYDKISEKKMSTPVESLCKNFPAEFAMYLNYCRGLRFEEAPDYMYLR QLFRILCRTLNHTYDYVFDWTLLKQKATA-MNPDKLKQRIGGKGSARRKKKVVHRTATAD DKKLQSSLKKLNVNNIPGIEEVNMIKEDGQVLHFNNPKVQASVASNTFAVFGHAENKQIT EMLPGILSQLGTENLSNLKKLASVTADIDEDDDEVPDLVENFDEASKGEXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXMGISRDSWHKRRKTGGRMPQLRKKRKFELGRPAANTKIGE QRIHMVRTRGGNQKFRALRLDHGNFAWGSEAVTRKTRIIDVVYNASNNELVRTKTLVKSC IVTIDATPFRSYYESHYTIPLGRKK-AKLTKEEE-------------------------- -----------------------------------------------MSLVLPEKFQHIL RVMNTNIDGRRKTPFAMTAIKGCGRRYSHLVCKKADVDVTKRAGEMTDEEVEKLITVMSN PRQFKIPDWFLNRQKDVKDGKYSQVMSNTLDNKLREDLERLKKIRNHRGLRHFWGLRVRG QHTKTTGRRGRTVGVSKKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKWQY KEEHPFEKRRAEGEKIRKKYPDRVPVIVEKAPKARVGDLDKKKYLVPGDLTVGQFYFLIR KRIHLRPEDALF---------------------------------------XXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLAIKFLEVVKPFCAVLPEVQKP ERKIQFKEKVLWTAITXFLFLVCCXIPLFGIMSSDSADPFYWMRVILASNRGTLMELGIS PIVTSGLIMQLLAGAKVIEVGDTPKDRALFNGAQKLFGMVITIGQAIVYVMTGMYGEPAE LGGGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVN TGRGTEFEGAIIALFHLLATRQDKVRGLREAFYRQNLPNLMNLLATIAVFGIVIYFQGFR VDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAAKFSGNFLINLLG VWADVGGGGPARS----------------------------------------------- ------------------------------------------------------------ ----------------------------------XXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX ------------------------------------AQGKRRYDRKQSGYGGQTKPIFHK KAKTTKKVVLKMECTSCKFKKQLPLKRCKHFELGGDKKKKG-----MGRVIRSQRKGAGS VFRCHNKHRKGAAKLRSVDYAERHGYIKGIVKDIIHDPGRGAPLAKVVFRDPYRYKLNTE TFIAAEGMYTGQFLYCGKKATLQIGNVLPVGTMPEGTIVCNLEEKMGDRGRLARASGNYA TVVSHNPDTRRTRVKLPSGSKKVIPSNNRAMVGIVAGGGRIDKPMLKAGRAYHKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGHASTVRRDTAHGRKVGLIAARRTGRLRGSKQAHG KXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XMTKGTSSFGKRHNKTHTLCRXCGGRSYHIQKSRCSACAYPAKRIRKFNWSVKAKRRKTT GTGRMRHLKTVYRRFRNGFREGTVPKK--------------------------------- ---------------------------DVHGQFHDLMELSVIGGRSPDXNYLFMGDYVDR GYYSVETVTLLVSLKVRYKDRITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDSQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHSNGLTLVSRAHQLVMEGYNWSHDKNVVTIFSAPNYCYRC GNQAAIMELDDALKYSFLQ-DPAPRRGEPHVTRRTPDYFL-------------------- --------------------RPTRPDKARRLGYRAKQGVCIYRVRVRRGGRKRPVPKGAT YGKPTNQGVNQLKFQRSLQATAEERAGRKCRGLRVLNSYWVGEDSTYKYFEIIMIDPANK AIRVDPNLNWMCAANKKHREIRGLTSASRKSRGLGKGHRYNKTTGGSRRANWKTNNSL-- ----GIALGRLAEERKAWRKDHPFGFVAKPTKNPDGTLNLMNWECAIPGKKGTPWEGGLY KLRMLFKDDYPSSPPKCKYEPPLFHPNVYPSGTVCLSLLDEEKDWRPAVTIKQILLGIQE LLNEPNIKDPAQAEAYTIYCQNRAEYERRVREQAMRFRDPSMGKSSKMLQHINYRMRCTL QDGRTFVGTFKAFDKHMNLILGDTDEFRRCRPKKGERKEEKRTLGLVLLRGENLVSMTVE GPPPADEGVARVPLPGSAGGPGMGRAAGRGMGGGGGLRGPVSGVGGPAPSHMQPG--MGR G---EDVPTFKLVLVGDGGVGKTTFVKRHLTGEFEKKYIATLGVEVHPLLFHTNRGPLRF NVWDTAGQEKFGGLRDGYYIKGQCAVIMFDVTARITYKNVPNWHRDLVRVCENIPIVLCG NKVDIKDRKVKAKAIVFHRKKNLQYYDISAKSNYNFEKPFVWLARKLTGDTALELVAMPA LKPPEVQIDPEMTAKYDQELQAAQNTALPEDEDDF------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----GARMVRELFVMAREHSPSIIFMDEVDSIGSTRLESGSGGDSEVQRTMLELLNQLD GFEPHQNIKVIMATNRIDILDSALLRPGRIDRKIEFPAPNEEARQDILKIHSRKMNLTRG INLR-------------------------------------------------------- -----LGFAENFALSGAAAVISKTAAAPIERVKLLVQNQDEMIKQGRLDKPYNGVVDCTM RTLKTEGVLPFWRGNLANCIRYFPTQALNFAFKDKIKALFGSKKTDGYMIKFSKNIASGG AAGAMSLCFVYSLDYARTRLANDAKS--KREYSGLIDVYRKTLKSDGVVGLYRGFVISCV GIIVYRGCYFGFYDTLKPILLGENAGVALSFALGYVVTISAGLVSYPIDTIRRRMMMTSG QAVKYKGSVDCFVQIVKSEGFMSLMKGAGANILRGVAGAGVLAGFDKFKSVYIQWRLXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX ---------------------------------AIRQIRVGNTAETKGTAFVVYEDIFDA KNACDHLSGFNVCNRYLVVLYFAPNRSYKKMDLEKKGAELDKMKQKYGLNTPD--XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMQSESGENVEM YIPRKCSASNRIITAKDHASIQINFAEVDESTGRMTGQYKTYAICGAIRRMGESDDCL-- ----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXMSERYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVR GNDIVVLGVEKKAVAKLQEDRTVRKIALLDEHVALAFAGLTADARILINRSRIECQSHRL TVEDPVTLEYITRYIAQLKQKYTQSNGRRPFGLSTLIMGFDGTPRLYQTDPSGTYHEWKA NAIGRSAKTVREFLEKHYSNDVATEKETVKLALKALMEVVQSGSKNMEVAVMRKGQPLTM MESDEIEKYIQEIEKEKEEEAEKKKQKQGGGAGDDKKDKDKKKRYEPPIPTRVGKKKKRA RGPEAASKLPSVTPHTRCRLKLLKSERIKDYLLMEEEFIRNQERLKPQEEKHEEERSKVD DLRGTPMSVGNLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDQLEPGCSVLLNHKVHAVV GVLGDDTDPMVTVMKLEKAPQEXYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIRPPK GVILYG------------------------------------------------------ ----------------------------------------------VIMATNRIETLDPA LIRPGRIDRKIEFPLPDEKTKRRIFTIHTGRMTLSDDVNLEDYIMSKDDLSGADIKAICT EAGLLALRERRMKVTDEDFKKSKENVLYRKNEGTPEGLYL-------------------- ------------------------------------------------------------ -------------------------------------------CDRIIPVDIYVPGCPPT AEALLYGMLQLQKKIKRMNLMQQWYRRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXX-GERYNIHSQLEHLQSKYIGTGHADTTKWEWL TNQHRDSYASYMGHFDMLNHFAIVENEAKARVRFNLMEKMLQPCGPPPDRPEDXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------- ----------QLEELKTELSQLRVAKVTGGQASKLSKIRVVRKSIARVLTVMNQTQKENL RKFYKPKDLRPKLTRAMRR----------------------------------------- ------------------------------------------------------------ -----GGKSIYFDDENFKLKHYGAGWLSMANAGKNTNGSQFFITTKKTEWLDGRHVVFGK ILEGMSVVRKIESSKTDRDKPSAPVVIADSGSLPVDKPFSVDKAPAEE--KKVEEKFYID CTHPVEDGIMDSGSFEAFLKERIKVEGKTGQLKTKVVVSANIKFSKRYLKYLTKKYLKKN NLRDWLRVVASAKDTYELRYFQINNEEEDDD---------EEDTKVGGCEGPDAMYVKLV SSDGHEFIVKREHALTSGTIKAMLSGPGQFAENETNEINFREIPXHVLQKVCMYFTYKVR YTNSSTEIPEFPIAPEXALELLMATNFLDC-KIIRKAELAQHKDAKSIWIAIHDKVYDIT KFLEEHPGGEEVLLEQGGRDGTESFEDVGHSTDARELLDQYLIGEFPEEERGTWSSWLLP LGIAIAAALVYRFIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------PPGCGKTMLAKXVAHHTTAAFIRVVGSEFVQKYLGEGPRMVR DXFRLAKENAPAIIFIDEIDAIATXRFDAQTGAXREVQRILLELLNQMDGFDQNVNVKVI MATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTVTSKMNLSEEVDLEDYVARPD SISGADINAVCQEAGMQAVRENRYVVLPKDFEKGYKNNIKKDQQEHEFYKXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------IFCNTKRKVDWLTDKM REANFTVASMHGDMPQKERETIMKNFRGGDSRVLITTDVWARGLDVQQVSLVINYDLPNN RELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLIMAMRRP FDPAAHDLEPTFRLTRFADLKGGCKVPQEVLLKLLAGLQEQGDTEQSHFQYVAAVPRIGI GMDCCVTPIRHGGLSLVQTTDFFYPLVDDPYMMGKIACANVVSDLYAMGVTECDNMLMLL APSQKMTEKERDVVLPLMMRGFRDTAEEAGTSVNGGQTVLNPWLTVGGVATTVCQPNEFI MPDNAVVGDVLVLTKPLGTQVAVNAYQWLDQPDKWNRIKLVVSEDDVRKAYQRAMFSMAR LNRTAARLMHKYNGHGATDVTGFGLLGHANNLARVQKNEVGFVIHNLPIIAKMAAVSKA- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------VFSMDIGDKPK AHHSKLEDMINELSTALTGVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMT LGQIYYLKRFFEVRRVVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXSRKKVLLKVIILGDSGXGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLV TMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMGNTFKTLDSWRDEFLIQASPRDPEN FPFVVIGNKIDMENRAVTAKRAQQWC---------------------------------- --------------------------AAPFDARFPNQNQTKNCWQNYVDYQRCLKVEQ-E SCTYFRRLYKSLCFSEVYKKWDEQVENGTFPVKI-------------------------- -------------------------------------------TGLAPPALWDLAADKQT XQSEQPLQVARCTKIINADSDDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNK YQIHIPLXPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGI DPPKGVLLYGPPGTGKTLCARAVANRTD-------------------------------- ------------------------------------------------------------ -------------------------------------------------------GADVR SVCTEAGMFAIRARRKMATEKXFLEAVNKVIKAYAKFSATPRYMTYNMGKERIHINIVVI GHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITI DIALWKFETERYYVTIIDAPGHRDFIKNMITGTSQADCGVLIVAAGTGEFEAGISKNGQT REHALLAFTLGVRQLIVGVNKMDSTEPKYSEARFNEIKKEVGSYIKKIGYNPETVAFVPI SGWHGDNMINMKWWKGWETGKGTTLLNALDNITPPTRPTDKPLRLPLQDVYKIGGIGTVP VGRVETGTLKAGMVVTFAPPIITTEVKSVEMHHTVLDQAEPGDNVGFNVKNISVKDIKRG NVCGDSKNDPPKGCESFEAQVIILNHPGQIGNGYAPVLDCHTAHIACKFKELKEKIDRRS GKKLEDKPAHVKSGDSAIVEMVPQKPMCVEAFSDYAPLGRFAVRDMRQTVAVGVIKSVTK KT-AEGKVTKAAQKAELEQLRQEAEQXKNQIREARKAAADTTLAXLPRASRPVGRIQMRT RRTLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDGYTXNKVHAIPLRSSWVMTCAYAP SGSYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIVTSSGDMTCA LWDIETGQQTTSFTGHTGDVMSLSLSPDMRTFVSGACDASAKLWDIRDGMCKQTFSGH-- ------------------------------------------------------------ -----------------------------------------------------MSYAYLF KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES FRSITRSYYRGAAGALLVYDISRRDTFNHLTSWLEDARQHASSNMVIMLIGNKSDLEARR DVKKEEGEAFAREHGLIFMETSAKTAANVEEAFINTAKEIYQKIQDGVFDINNEANGIKL GPQQPSNPSNSAAGSSQGAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPKQ IKEIKDFLLTARRKDAKSVKIKKNVKFKVRCSRYLYTLVISDREKAEKLKQSLPPGLSVK ELKMSKLNRETVSEAIDTILQKKRKFTESVELQISLKNYDPQKDKRFAGTVKLRAIPKPK MNVCILGDQQHCDEAKANNVPCMDADALKKLNKNKKLIKKLAKKYDAFLASDTLIKQIP- ------------------------------------------------------------ -----------------------------------MAESDKLNIDSIIARLLEVRGSRPG KNVQLTETEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDEC----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MFKNTFQSGFLSILYSIGSKPLQVWDKKVRNGHIKRITDNDIQSLVLEIVGTNVSTT YITCPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPF ICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDEL PAEFKLYLPVQNKMTDSTIQNLQDPFADENEIHIRIQQRNGRKTLTTVQGLSADYDLKKI VKACKKEFACNGTVVEHPEYGEVIQLQGDQRKHVEDFLITVGLSEKLKVHGFXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------LIIY DDLSKQAVAYRQMSLLLRRPPXREAYPGDVFYLHSRLLERAAKMNDNFGGGSLTALPVIE TQAGDVSAYIPTNVISITDGQIFLETELFFKGIRPAINVGLSVSRVGSAAQMKAMKQVAG SMKLELAQYREVAAFAQFGSDLDAATQQLLNRGVRLTELLKQGQYVPMAVEDQVCVIYAG VRGLLDKIDPSRITAFEAAFLAHIRSQHQDILKSIRENGQIIPETDAKLKEVVVDFLAGF -----------------------------------MVMLSYFLVTGGIIYDVIIEPPSIG STTDEKGNSKPVAFMPYRVNGQYIMEGLASSFLFMIGGLGFIVLDQTNKPLMPKLNRILL LCVAFVCILLSFFVCRVFMRMKLP-----------------------------REAELDP HEGKRKVEALWPIFRIHHQKSRYIYDCFXKRKAISRELYDYCLRESIADANLIAKWKKQG YENLCCLRCIQARDTNFGTNCICRVPKGKLEEGKIVECVHCGCRGCSG------------ -----------------------------DIILIGLRDYQDQKADVILKYTPDEARSLKA YGEIPESAKINDNEDDIITFEEIDDILVRFLMKLSHETVTIELKNGTQVHGTVTGVDVSM NTHLKSVKMTIKNREPVQLETLSIRGNNIRYFILPDSLPLDTLLIDDAPKSRGRG----- ------------------------------------------------------------ -KNVKEMWTEVPKTGKGKKKSKPVNKDRYISKMFLRGDSVILVLRNPLPLVIDGRGHLLG RLASIIAKTLLQGQRVVVVRCEEINISGSFYRNKLKYMEFLRKRMNTNPSHGPYHFRAPS KILWRTIRGMLPHKLHRGKEAMDRLKTFEGIPPPYDKEQRKVIPAALKVLRLKARRRFCV LGRLSHEVGWKYQNVISTLESKRKVRSGQYYKKKVAENKL-------------------X XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------- -------------------------------------FFPSLVAYMSSGPIIAMVLAKER AISYWRELIGPTNTLKARQTHPDCLRAIFGTDDQRNGLHGSDSYGSAEREIRFFFSDSIT EPVGMGQAAKDYLAKAVNPTLLKGLTQLSKQKPLDPVIWLADWLLENNPNKPKVKMFEAR LAQGSLLKKVIESIKDLLSEGTWDCNSSGMSLQAMDSAHVSLVSLMLRSDGFDTYRCDRN LSMGIHLGSMSKILRCAGNDDAITVKASDNADTITFMFESPNAEKVSDYEMKLMDLDSEH LGIPETDYSCVIKMPSGEFQRICRDLSQIGESVIICCTKEGVKFSATGDLGTGNVKLAQT ANVDKEEEAVIIEMQEAVTLTFALRYLNFFTKATPLSGQVSLSMSPEVPLVVEYKIGEMG YIRYYLAPKIEDGDD-KPFAAYQTSSKNPQGKIVAVIGAVVDVQFDEELPPMLNALEVQG RDSRLVLEVAQHLGESTVRTIAMDGTEGLVRGQVCVDTGSPISIPVGPETLGRIINVIGE PIDERGPINAKATWGIHQDAPEFVEMSVEQEILETGIKVVDLLAPYAKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVIKLEDDTSKVALVYG QMNEPPGARARVALTGLTVAEFFRDEEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIA ELGIYPAVDPLDSNSRILDPNVVGEEHYKVARGVQKILQDNKSLQDIIAILGMDELSEED KLTVARARKIQRFLSQPFQVAEVFTGSAGKLVPLKESIKGFSMILNGELDHLPEMAFYMV GPIEEVVAKAETLAKD-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXMGNQATALRPEVLDDLAESTQFTPEEIREFYRTFLKDTDHGRL SEEEFREAYTRVFPSGDASKFSKHVFDTYDLDGNGRLDFREFLSSLSVQQRGSFEEKLEW XFNLYDIDKTGTISKDELIEMIKSFRRMKG-AMAPGLNNVAPEDMAEYIIEKADTNSDRV LSRDEFFKAAKSSKTL--------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX MTNTKGIRRGTRYMFSRPFRQKGVIPLSTYMKVYKRGDIVDIKGNGAVQKGMPFKAYHGR TGRVYNVTRHAVGVIVNKRVRGRIIPKRINVRIEHVKH---------------------- -------------------------------------XXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXKQLTKEEELLLQDFSRNVSTKSSALFYGNAFIVSAVPIWLFWR IHQMDPIILFSVVTIVSTYLVAYAYKNVKFXLKHKIALKR-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------SLRKKLPKT EQSVDLSQDQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX----------------EPVPGIQANPDESNARYFHVIVAGPKDSPYEGGIFKLELFL PEEYPMSAPKVRFMTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPD DPLANDVADQWKTNESQAIETARQWTRMHA------------------------------ ---------ELLRAIVDCXFEHPSRXSYECIPQAILGMDVICQAKSGMGKTAVFVLATLQ QLEPVDNQVSVIVLCHTRELAFQISKEYERFSKYMNSTKIAVFFGGMPIKKDEEVLRTNC PHIVVGTPGRILALTKKLNMKHVKHFILDECDKMLDNLDMRRDVQEIFRMTPHEKQVMMF SATLSKEIRPVCKKFMQDPMEVYVDDDSKLTLHGLQQHYVKLKDHEKNRKLFELLDALEF NQVIIFVKSVQRCMALAQLLVEQNFPAIAIHRAMTQEERLSRYQQFKDFQKRILVA---- ----------------------------------------------------PPSYSDLG KSARDLFNKGYNYGFYKIESKTKASNGVSFTANGSSNHDSGRFNGSLETKYKCSDYGLTF TEKWNTDNTLGTEINIEDQIVKGLKLAFDTQFAPQTGKKSGKIKTAYKQEYINTSCDVDF DFAGPTIHGAAVAGYNGWLAGYQMSFDKSKLSRSNFAVGYAAGDFTLHTSVNDGTEFYGS VYQRVNPELETGVQLNWTAGSNATKFGLAAKYTLDKDSSVRAKVNNASQIGVSYQQKIRD GVTFTLSSLVEGKNFNQGGHKVGLGLDFEA------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------DKYIGES ARLIREMFAFARDHEPCIIFMDEIDAIRRFSEGTSADREIQRTLMELLNQMDGFDALGQV KMIMATNRPDTLDPALMRPGRLDRKIEIPLPNEQARLEILKIHASPIAKHGEIDWEAVVK LSDDFNGADLRNVCTEAGMFAIRSERDYVIEEDMM---------------------MPES LGTVVSKFYNEYMSSTPKKIKIIDAYLFYVLLTGAFQFLYCCLVGTFPFNSFLSGFISCV GSFVLGVCLRVQVNPSNKTEFLGVGPERAFADFVFANVILHLVVMNFIGXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXVIDHYENPRNVGAMDKEDKNVGTGLVGAPACGDVMKLQIKVDENG KIVDAKFKTFGCGSAIASSSLATEWIKGKNLDDAGKIKNTDIAKELCLPPL--------- ---------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXMGRFMKPGKVVLVLGGRQAGKKGIIVRNYDEGTADHPFPHALVA GIDRYPRKVTKSMSKKKLKQRSKVKPFVRVYNFNHLMPTRYSVVNFDKQSVNKDAFRDPA LRWKARNEIKAKLEERYKTGKNRWFFQKLRFERTFIMVKPDGVHRGLVGEIMKRFEQRGY KLVGIKTMQASKELLEKHYADLSSKPFFPGLVNYMASGPVVPMVWEGSVVKMGRQMLGET NPLASLPGSIRGDFCIDIGRNICHGSDSVESAKKEIALWFNEAEVLTWTQSGEDWVYE-- ------------------------------------------------------------ ----MDQYAIVKYPLTTESAMKKIEDNNTLVFIVHKLANKPQIKLAVKKLYDIDAAKVNT LTRPDGEKKAYVRLAPDYDALDVANKIGIIMPAKQRMRVANEKAASKVTIRGNVPTTLKP SEDKYPVGPWLLGLFIFVVCGSAVFQIIQSIRMXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX X----------------------------------------------------------- ------------------------------------------------------------ -----------------EVANALGLSAIKNRKYQIFKTSAIKGEGLDEAMEWLANTLSN- -XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXX------------------------------------------ --------------GMVQPSRGFVVXPVKYKAIVFRPFKGEVLDAVVTQVXKVGIFTEVG PLSCFISRHSIPPDMEFDPNSVPPCYKTKDEDLVIQQDDEIRLKIVGTRVDATDIFAIGT LMDDYLGLVSRLYVKAVFTGFKRGLRNQHENTALLRIDGVTERKDTDFYLGKRCAYVYKA NNRTACPGHEKASRIRVIWGKVTRAHGNSGAVRAQFRKNLPPIAMGRRVRVMLYMAKKTY DLLFKLLLIGDSGVGKTCLLFRFSDDAFNTTFISTIGIDFKIKTVELGGKKIKLQIWDTA GQERFHTITTSYYRGAMGIMLVYDITNAKTFDNISKWLRNIDEHANEDVEKMILGNKCDI EDKRQVPKDKGENIA--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----GVKKNPSSPLFTQLGVITKGTVIEVNXSELGLXTQAGKVIWGKYAQVTNNPENDGC INXV---MAARPLITVYSEKGEATQSNITLPAVFRAPIRPDIVSSVHNDMKRNSRQAYAV SEKAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRR INVNQKRYAICSAIAATGIPSIVMSKGHRIEQIPEVPLVLSDKVEEIKKTKEAVGILRKV KAWPDIEKAKASKRFRAGKGKMRNRRRIQRRGPLVIYNQDNGITRAFRNIPGITLINVNR LNLLKVAPGGHVGRFCIWTEAAFNKLDALYGTWRKQSEEKNNYNLPMPKMTNNDLTRLLR SDEIQKAIRAPKNDRKRAVLKKNPLKNWRTMMRLNPYAHVQKATAISKAKRQAAIDEKRG ITTVDTGGKARPRKTTKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXX----------------------------------- -------------------------EEDPED-VPHGHITSLAVKRSHRRLGLAQKLMDQA SRAMVENFNAKYVSLHVRKSNRAALHLYQKMLRFEISEIE-------------------- ----MSHTILLVQPSTKPEGRTYSDYETVNECLEGVCKIYEEYLKRMNPQAPSITYDISQ LFDFIDQLADLSCLVFEKQSGKYAPHNKAWIKEKIYILLRKQAGKMAEEGQEKKQEEVKR --HTYPLIRHSDMHEEMRVEAMELCVTACEKFANNNENAAKLIKETMDKKFGASWHVVVG EGFGFELTHEVKNILYMFFSGNLGIVVWKCSXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXX---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------RLHVWDLSKIGEEQSAEDA EDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEEPESSAG DVEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXMQFMLLFSRQGKLRLQKWYVAHPDKLKKKITRELITTILARKPXMCSF LEWKDLKIVYKRYASLYFCCAIEASDNELLTLEIIHRYVELLDKYFGNVCELDIIFNFEK AYFMLDELLLGGEVQETSKKNV-------------------------MSKAHPPELKKYM DKRLTLKLNAGRVVTGILRGFDPFMNLVVDEAIEECKTGEKNTIGMVVIRGNSVVLLEAL ERIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMLDNMDFLDDVRRMNARQLYYQ CLNFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNYREEPIRVGE IVVFKVEGRDIPIVHRVLKVHEKENGEVKFLTKGDNNSVDDRGLYAPGQMWLHKK----- ------------------------------------------------------------ ----------------------------------------------GQERFRTITSSYYR GAHGIIVVYDVTDQESFNNVRQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDFTTAKEY ADQLGIPFLETSAKNATNVEQAFMTMAAEIKNRMGPETKAPNVKIGSSTPVKQGGGGCCX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKDAADQ NFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRQDKRVKLQIWD TAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDNAQVVLVGNKC DLEDERVVSTERGKQLADQLGLEFFETSAKENINVKAVFERLVDIICDKMSELIDSDPTQ TTRLTEKPNPQNAGCQCXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXSGPGFIGIKFCQECNNMLYPKEDKENRTLLYACRNCDYQQL SDNPCIYVNKIQHEVDELTNIIGDVIVDPTLPRTELHPCPNCGHKEAVFFQSQSNRAEQG MRLYYVCCSNSCMHRWTE------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------VVTG PIFEQMLEDTIVCNIGHFDCELDVKYLNDNAAKKDTIKPQVDRYTLKSGRHIILLAEGRL VNLGCAMGHPSFVMSNSFCNQVLAQIELWAGKKQYPIGVHFLPKKLDEEVAAAHLEHLGA KLTHLTEDQASYLGIPREGPFKPDHYRYADDREEQPTNAVEEPLDLIRLSLDERIFVKMR NDRELRGRLHGYDQHLNMILGEVEETITTVEIDEETYEELYKQKKRNVPMLFVRGDGVIL VSPPMRT---------------------------------------------AAVEGPAG TPYAGGIFRIKLILGKDFPSVPPKGFFLTKXFHPNVAANGEICVNTLKRDWKADYGVKHI LLTIKCLLIVPNPESALNEEAGKMLLERYEDYCSRAKLFTELYAKPMFKSLLEAASSSPF STPFGLKVNENRLIAAADDEYSCEFGDNKYYALCGFGGVLSCGITHTAVVPLDLVKCRIQ VDAAKYGGIVNGFRVTVREGGPMELTKGWAPTLIGYSMQGLCKFGFYEVFKNIYGNLLGE EKAFLYRTSLYLAASASAEFFADIALCPMEAVKVRIQTQPGWANSLREGVPKLMSEEGVG GFYKGLVPLWGRQIPYTMMKFACFERTVEALYKFVVPKPRADCSKGEQLIVTFVAGYIAG VFCAVVSHPADTIVSKLNKDKTATFMDVAKNLGWKGMWMGL------------------- -------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------- ERLKRLLISEVAEKYRMKVAEDEQELSEVFLKTLGATERFSKFKNRETITAVRSLLMQKK LHKFELAALANLCPETAEEAKALIPSLEGRFEDDELQSIIDDIQTQRSFQYXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----RVYRIFSHAYFHHRQLFDEYENETALCKRFTVFVTKYDLMAKNNLIVPILDDQ--- ------------------------------------------------------------ ----------------------------DQGTLFELILAANYLDIKGLLDVTCKTVANMI KGKTPEEIRRTFNIKNDFTPAEEEQVRKENEWCEEKXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------ ------------KNKATMGHLGLLKARLVKLRRELIEPXGGGGGTGEGFDVAKTGDARIG FVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDG KGRGKQVIAVARTCSLIYIVLDVLKPLQHKRLIE-------------------------- ------------------------------------------------------------ KDDQISIEELDIIYKIPHCVPISAHHKWNFDDLLEKMWEYLCLVRIYTKPKGQLPDYNA- ------------------------------------------------------------ ----------RKQPGVAIGRLCEKCDGKCVICDSYVRPNTLVRICDECNYGSYQGRCVIC GGPGVSDAYYCKECTIVEKDRDGCPKIVNLGSAKTDLFYERKKYGFKKRPQLPPVSASKL TGKSSMRKIPVPPNRYAPLKDQWMKIFTPVVEVLNLRIRFNLRTRNVEIKTCKQTTDVGA LQKAADFVLAFTYGFE-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------FQKSGGVLMG MYNTDESIMGFAHSCMQYALKKKWPLYMSTKNTILKRYDGRFKDIFQDIYEKDYVKEFES NGIWYEHRLIDDMVAQALKSNGGFIWACKNYDGDVQSDVVAQGYGSLGLMTSVLMCPDGK TIEAEAAHGTVTRHYREHQKGNATSTNPVASIFAWTRGLEHRATLDNNPDLARFCQTLEK ACIDTIDSGKMTKDLAGCIYGIKNVTSDQYLVTNDFLEAIREEFEXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------- ------------------------------------------------------------ ---------------EKERIKEERLKAYHEKKAAPLIAKSSILLDVKPWDDETDMAALEK AVRSISTDGLLWGASKLVPLAYGIKKLQINCVVEDDKXGTDFLEEEITNFEDYVQSVDIA AFNKI------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --EIKQILKIRCEEEDVEMTDDAMTVLTRIGMETSLRYAIQLITTASIVTRKRKGTEVNM DDIKRVYSLFFDESRSSQFLKEYQQEFMFNE----------------------------- -------------------------------------------------------LQAET EPITKIFEHEDVRFSQPEMGGNYFEFLSTTYGFKQEMVDTLYRFGKFQYECGNYSGAAEY LYFVRVLLPPPTR----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------MGVDNVTITPGDGSTYPKTGQTVSVHYVGTL PDGKEFDSSRKRGKPFNFKIGQGQVIKGWDEGVKKMSLGEKARLTCSPDYAYGEKGFPGA IPPNATLIFEVELLGLQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXX---LVGAALAEPTVYFKDDFFSSRWVGSTHKGSEQ GKFKWTAGKFYGDAEKDKGIQTSEDARFYGLSAKFDEPFSNEGKDLVIQFSVKHEQNIDC GGGYAKIFPSDLDQKDMHGDSPYLIMFGPDICGPGTKKVHVIFNYKG------------- -------------DNTYEVKIDNEKVESGDLEADWDFLPPKKIKDPEAKKPDDWDDVEKI DDPEDSKPEDWDQPEHIPDPDAKKPDDWDDEMDGEWEPPMIDNPEYKGEWKPKKIPNPNY KGPWIHPEIDNP------------------------------------------------ --------------------------------------------MDCPLPEPSLITVKAI LILDNDGNRLVLRRYTVTPXNPKERQTLYQGLKTSNSDQIMLEGLTCVYRSNVDLFFYVI GSVQENELILVSVLNCLYDSVSQMLRXNVEKKALLENLDAVFLAVDEICDSGIILEADPN AVCSRGGFRSDDIPLGEQTVAQVITQAKDKFKWNLLRMNIFRLIGDLSHLLAIILLLMKI WKTRSCAGISGKTQIMFALVFLCRYLDLFTXFVSVYNSVMKVIFIASTLGTVYLMLFKFR ATYDSNHDTFRMEFLXVPVAGLSFLVNHDFSPFEILWTFSIYLESVAILPQLFMISK--- ------------------------------------------------------------ ---------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------- ------------------------EVEGPGPQRSVEGWILFITNVHEEANEDDIIDKFRD YGEIKNLHLNLDRRTGFLKGYALVEYETFSEAQSAMEKLNGEDILGQTISVDWAFVRGPS K--------------------LDELIQMGQISPSLALKVLLQFDKEINNALSTRTKNRIS FSGKLNTYRFCDNVWTFVLKDVHFKAVDKVKIVACDGKSTFLFTSESVGEGHPDKICDQI SDAILDAHLKLDPNAKVACETAAKTGMIMLLGEISSKTHIDYQRVVRDTIKYIGYDDSEK GFDYKTCNVLSALEEQSPDIAQGVHIGRDEDDIGAGDQGLMFGYATDETEQAMPLTIMLA HQLNSKLSELRRNGGLPWARPDSKTQVTCEYRMENGACVPLRVHTVVVSVQHSEDIELEQ MRAEIMEKVVKAVIPARYLDSNTIYHIQSSGRFVIGGPQSDAGLTGRKIIVDTYGGWGAH GGGAFSGKDFSKVDRSAAYAARWVAKSLVKSKLCRRVLVQVSYAIGLAEPLSIYLSTYGT GIKPDADILQIVKKNFDLRPGRIVKDLDLKRPIYQKTAVYGHFGRSEFPWEQEKKLVFXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMRLEKCYFCSSTVYPGH GSTFVRNDAKVFPFCRTKCLNAFKKKRNPRKVRWTKAFRKASGXELAVDPSFEFEKRRHV PVKYNRQLWTETIKAMKRVEQIKTKREAQHIKERLKKGKQLRKAADIKEVXKNLHMIKSP AAKMAKYIVVMVRHGESEWNKENKFCGWFDADLSDQGIKEAKSAGQMLKEKGYKFDIAYT SVLKRAIKTLYHIQNETDQHWIPVIRNWRLNERMYGALQGLNKAETAAKHGEEQVQIWRR SYDTPPPPVETSDSRFPGLDPKYKFVDQQLIPRSECLKDTVARVLPFWYDSIVPEILQGK RVIIAAHGNSLRAMVKYLDNMTDDAIMKLNIPTGIPLVYELDAKLKPIKHYYLADEAAVK AAIDKVAAQGKAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------------------- ------------------------------------------------------------ ------RVVLNTLTKHFKVYITQRAGEEMAKEVEALGIPTIVILDSAIAYIMDDIDMVLL GAEGVVESGGIINKGSLTMATCA------------------------------------- -------------------------------------XXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------ ----------------KSRFWYHSSLLKKMKKGKGEILDCTQINEKYPQKIKNFGIWLRY VSRSGIHNMYREYRDLTTASAVTQCYRDMGARHRARACNIQIIKVEVVPASKTRRTGVKQ FHNSSIKFPLPHRVSKRLHTPRFTTNRPHTHFTAHEQMKAFWEKNQKRPSSPWIIYRSHI PMLTSLTHRVTGIAMGVVLYGIAIGTYVAPGDFPMYVEYLKNLQLP-------------- ---------------------------------------XXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXX------------------------------------------------------- --------------------EDDSVRIWDCVTGTCINELEGETEHVAHCGFSPGGALMAS GA---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------- ------------------------------------------------------------ ----------------------------VGVIQAADLPGMDMSGTSDPYVKVYLLPEKKK KFETKVHRKTLNPVFNETFVFKVAYAEIGSKTLVFAIYDFDRFSKHDQIGQVQVPLNSVD LGRVVEEWRDLASPESE-EKENKLGDICFSLRYVPTAGKLTIVILEAKNLKKMDVGGLSD PYVKLSLMLNGKRIKKKKTTIKKCTLNPCYNESFSFEVPFEQIQKVTLIVTVVDYDRIGT SEPIGRVVLGCNSTGTELRHWSDMLANPRRPIAQWHTLQEMPEKNXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------RRDDYVHALVAFFNIEFTKCHKKTGFSTAPEARYT HWKQTNDAITCNKGEEVHGVFHTKPNKNNVRDLDFTIDVAFNGELSSVRESNSYKMRMVK GDRATWKSNYFIKMVQLLDEYPKCFIVGADNVGSKQFQSIRSNLRILMGKNTMMRKAIRG HLDNNPALEKLLPHIKGNVGLVFTKLDLSDVRDKIVNNKVAAPAKAGAIAPLDVILPAQN TGMGPEKTSFFQALAITTKITKGTIEILNDVHLIKEGDKVGASEATLLNMLKISPFSYGL IIQQVYDSGTVFSPEILDITDDDIRARFMQGVSNIAAVSLAIGYPTVASAPHSIANGFKN --------------------SAQKGKLIAVIGDEXTCTGFLLGGVGELDKNRRANFLVVX KGTSVSDIEDSFKRFTKRQDIAIILINQNIAEMIRHILXTTKKPLPAVLEIPSKRXPYDP SKXPILRRAKGMF------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--MVTKSIGGKENGDKR TVRVNRFPKSYETQVRGRKLKGAFSQHKRNLRASITPGTVLILVAGRHKGKRVVFLKQLA SGLLLVTGPYALNGCPLRRVSQNYVIATKTKIDVASVKLPERLTDNYFKRKVLNKPKHQE GEIFDTKKEEYSVSAERKEDQIAVDKALMAAIRARDDKKYMFGYLGAMFSLTNNQYPHKM IFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXDDFMVGDEDYDLEYSEDSNSEPDVDLENQYYNSKALKEDDPRQALES FQKVLELEGTDKGEWGFKALKQMIKINFKLGKYPEMMNRYKQLLTYIKSAVTRNYSEKSI NSILDYISTSKQMELLQNFYETTLDALREAKNDRLWFKTNTKLGKLYFDREEYSRLQKIL KQLHQSCQTDEGEDDLKKGTQLLEIYALEIQMYTAQ------------------------ ------------------------------------------------------------ ----------KNDPEILAMTNLVSAYQNNDIGEFEKILKTNRQNIMEDPFIREHIEDLLR NIRTQVLIKLIRPYTSIHIPFISKELNIDVADVESLLVSCILDDTVKGRIDQVNQVLRLE VGSSRYAAMDKWSQQLASLHQSIVNKMAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXX----------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----YEIMRELDVNYVLVIFGGLTGYSSDDINKFLWMVRIGGSTDRGAHIKEHDYYTPQ GEFRVDKEGXPTLLNCLMYKMCYYRFGSVYTESGKATGYDRVRNAEIGNKDFELDVLEEA YTTEHWLVRIYKVKDLENRGN--------------------------------------- -----------------------------------------------------LHAGQDI RVLGENYSLADEEDSRHATVGRLWISEARYKIEVNRVPAGNWVLIEGIDQPIAKTATLTE PTGNEEAHIFRPLKFNTQSVMKIAVEPVNPSELPKMLDGLRKINKSYPLVTTKVEESGEH VVLGTGELYLDCVMHDLRKMYSEIDIKVADPVVSFCETVV-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------------SP LYIIKAFIPAIDSFGFETDLRTHTQGQVFCLSVFHHWQIVPGDPLDKSIVIKPLESQPAT HLAREFMXKTRRRKGLSEDVSINKFFDDPMLLELAKQDVMLSYGMXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------EIIRNTLY KXYRRDFYKFCEEMGGPTAEVMCEALXFEADRRAFIITINSFGTELSKDDRSKLYPRCGK LNPRXSQPLARADDYEQVRAVADYYGDYRTLFEDSGNNPRQNVLEDKFL----------- ---------------------------------------------XXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXX--IIIGLYLVLSGNGYRFDVKWFLEGISPYLWCNLGIGLAISLS VVGAAWGIYTTGSSILGAGVKAPRIRTKNLVSIIFCEAVAIYGIIMAIVISNAQNYFAGY SMFAAGLTVGFSNLFCGICVGVVGSGAALADAQDASLFVKVLIIEIFGSAIGLFGVIVSI LQTTKINMGN-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDASDTYPEQCSKLRKGGYVMIKDKPCK VMEMSTSKTGKHGHAKVHYVGLDVFTGKKYEDICPSTHSVNVPHVTRFELPVIDI-EGFI TVMEDAGDTREIAKPEAVIWKACGKEEALDLKSVK------------------------S GIFVFQSNGKLISKFGSRGPHEFAGPHFCTVNQVNDIIVSDFHNHNIKVFNEGSFLFAFG SHGEGNGQFKATTGVAVDKHGNILVADWGNARIQVFDSQGSFLSYINCMXSQGLSLSESG HLVVADSANHCIKVY---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXX---------PLFEKRPKNFGIGQGYPAEAXLSRFVRWPKY IRLQRQKAIIMQRLKVPPSINQFSQTLDRQTASQXFRLLDKYRPESKIEKKQRLKARAGG ESKGKPDAPTKRPAVVRSXSTQSTSLVEQKKATTVLLLTIVDPIELVLVRPALWDRKSVP YCYCRGRVVPPQDCLTTSFEENPTLDGPPLALETSVGGTAXNELNLQRSRSWGGGIMGNK SQAKVAKLEKARAKELMQRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--VESVKAR QIFDSRGNPTVEVDLKTDKGMFRAAVPSGASTGIYEALEMRDKVKELYHGKGVSQAVNNV NSVIAPALVFDLSDQKALDKLMLSLDGTDNKSKLGANAILGVSLAVCKAGAAQKGVPLYR HIADLAGNKDLVLPVPALNVINGGSHAGNRLAMQEFMILPTGASSFTEAMRMGSEVYHHL KNVIKAKYGQDACNVGDEGGFAPNIQSNNEGLELLKLAIEKAGYTGKIEIGMDIAASEFC KKYDLDFKNKDSNPADWLASDALLEVYKGFVKDFPVVTIEDAFDQDDWSAWSKMAAVQLV GDDLLVTNPKRVKDAIEKKACNALLLKVNQIGSVTESIEACKMSQKAGWGVMVSHRSGET ED-----------------------------------------------------XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX---------FLLYDGEKKVTIEKDTKVPNCAIFTINKEDHTLG NTIKTQLLKDPHVLFAGYKNPHPLESKIVIRIQTDADYSPQEALTNAITDLISEVSLLEE RFKEAIREKQEGDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXMGCTMSAEERSAMERSKQIERNLKEDGIQAAKDIKLLLLGAGESGK STIVKQMKIIHEGGFTNEDNKQYKP----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ EEAAAYIQAQFEAKNKSTTKEIYCHQTCATDTNNIQFVFDAVTDVIIANNLRGCGLYXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------EIYQNIQDGSLDLNAAESGVQHKPSAP RSTLSNDTQPTKEGCSCMSVKAVCVLKDSEVTGTINFSQEG-VKVSGEIKGLAPGQHGFH VHEFGDNTNGCISAGPHFNPHKKEHGAPCDENRHVGDLGNVTAGKIDISDKQISLSGPQS IIGRTVVVHADIDDLGKGGHELSKTTGNAGGRLACGVIGIARMVNFTVDEIRAIMDKKKN IRNMSVIAHVDHGKSTLTDSLVSKAGIIAGAKAGETRFTDTRKDEQERCITIKSTAISMY YNMEESDMETGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQA IAERIRPVLFMNKMDLALITLQLGSEELYQTFARIVESVNVIIATYNDETSPMGDVMVDP AKGTVGFGAALHGWGFTLKQFAEMYAEKFKADSKKMMKRLWGDQFYNYKRGFTQYILDPI YKVFDFTMPKEEALALVEKLGIKLSMEEKEKQEKQLMKVVMRKWLPAGEALLQMITFHLP SPVTAQKYRTELLYEGPKEDEAALSMTACNDQGPLMMYISKMVPTSDKGRFYAFGRVFSG KVKTGQKARIMGPNFVPIKSIQRTILMMGRYIEPIEDVPCGNICGLVGVDQYLVKTGTIT TFEAAHNMKVMKFSVSPVVRVAVDCKNPSDLPKLVEGLKRLAKSDPMVQCTIEESGEHII AGAGELHLEICLKDLEEDHACIPIKKADPVVSYRETVAEESGIMCLSKSPNKHNRLFMKA INMPDGLAEDIDDGKITPRQELKERARYLAEHYDYDVTEARKIWCFGPDGTGPNVIMDCT KGVQYLNEIKDSVVAGFQWASKEGVLCEENMRGIRFNLYDVALHADAIHRGGGQIIPTAR RVLYACALTAQPRLLEPIYLVEIQCPESVIGGIHSCLSTRRGHVIDQQQGSNAQMFTVKA YLPVNESFGFTADLRSNTQGQAFPQCVFDHWQLLVVKATRTRKGLKEGIPPLDNFFDKLX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXMDDEQETYKIWRIRKTVMQLCHDRGYLVTQDELDQTLDQFKEQFGDKP SERHPSRSDLIVLVAHNDDPTDQMFVFFPDDPKVGIKTIKTYCQRMQEENIHRA------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------TLTRAKFEELNMDLFRSTMK PVQKVIDDADLSKSEVDEIVLVGGSTRIPKIQQLVKEFFGGKEPSRGINPDEAVAYGAAV QAGVLSGEDATDGLVLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQIFSTAADNQPT VTIQVFEGERPMTKDNHLLGKFDLTGIPPAPR---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------PELEAIKARVREMEEEAERLKEMNSQVDKQMSQEEKLDADQRSV YVGNVDYGATAEELEAHFHGCGSVNRVTILCDKFTGHPKGFAYIEFADKDSVQTAQALDE SLFRGRQIKVTAKRTNRPGVSSTDRPPRGRF-RGRGGGYRGGYNPR---RPRYRARRVVY YQPY------------------------------------------RKRMKQLQKQLADV KEEKIKDIEERNEMIAHLKDQLQEMKAKTNMEGKYIKKCAEVSVAQTQKRCMMSEKEMKE EIERLKQKIDEENRCNAEIESFLRTHTELLSKKVEEWMEKYDKDVEAKQKQLDILKASKA KDLERLKELTKLYAEYEQVVVEDRXRK-KARRKAEMEAEELKSAIRLQSWWRGVMVRKGL GPYSKKKKK-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------DGGGAADRVINQLLTEMDGMTSXKNVFIIGATNRPDIIDPAILRPG RLDQLIYIPLPDQGSRMAILKANLRKSPVAPDVDQNYLATITEGFSGADLTEICQRACKM AIRESIEEEIRGKNARRQPXDDFDPVPEYXRAHFEEAMKFRPCSVS-------------- --------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------- ----GDKPHLQKYQVDLNECGPMVLDALIKIKNEDDATLTFRRSCREGICGSCSMNINGA NTLACLCKIDANTSKTTKIYPLPHMYVVKDLVPDMNNFYAQYKFIEPY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------QALQ GFKITPENAMKISFAKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXX--IPTRSVVLTDPSQLPHDYGTTPGGTLFSTTPGGTRIIYERNFLLQCRNSPLA KSPPAQPP---------PPGKRKEIYKYEAPWTVYSMNWSIRPDKRFRLALGSFVEEYNN KVQIVSLDEETSDFVSRSTFDHPYPTTKIMWIP--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------XXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------- -LTSDPKLPYKVLSVPEATPFTAVLKFAAEEFKVPAATSAIITNDGIGINPAQSAGNVFL KHGSELRLIPRDRVG-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------- ---------------MTHALIEAYDLLPHLTVISPSPASVTDLTAFHSEDYVVCLQKLED EDKEKLQEEAEEYGLLYDCPAYDGVYEYASYVAGASLKAAECLARKETRTAINWGGGWHH AKRDMAS----------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------LQM QDIPEDAIKDEVRIPRRTTQTASDKRITCEEEFSDSEDEGGGGRRNRESHKRKRLXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXX------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------NYESQTGHSVHLRGLPFAATEQDILDFFKPLNPVNVVVH YNNGRASGEADVDFATHDEAKEAMRKDRGTMQHRYIELF--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------SMTDTELV DGLVFSQRSAGYGGPHKVDKAKIGLIQFCISPPKTDMDNQVIVSDYTQMDRVLREERQYI LNIVKQIKKAGCNVLLIQKSILRDAVNDLALHFLAKMKIMVIKDIEREDIEFVCKTLGCR PAASLDHFTADSLGSAELVEEVQAGDSKIVKITGIVNAGKTMSIVVRGSNKLVLEEADRS IHDALCVIRCLVKNRALIAGGGAPEIELSLRLNEYSNTVTGVEQYCFRQFAEALEIIPFT LAENAGLNPIATVTELRNRHAQGERTAGINVRKGAITNILEENVVQPLLVSTSAIHLASE TVRSILKIDDIVNCM--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------ITFVLFPR HENRDNTINLIHTLRDYLHYHIKCSKAYIHSRMRAKTSDFLKILNRARPE---------X XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------DVMMDFDALVQ AQSGLGTAALIVMNKQADVVRCISRLMEFYKHESCGQCTPCREGVNWMNQILKRFVSGNA RAEEIDMLWEISKQVEGHTICALGDGAAWPAQGLIRHFRPLLEKRFADYHAKNXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXX---------------------------------------------LQNGETPP VKQRLEMPQATQKTDTGLTPGLLRVLNKQLGPKKVVPLKMIEDKWSDLALPKEQFDELVR VGTFSGNVEWLKFFALGCSALGENIKDAMKTVCEILTADPDGGPARIPFPLFKELYSYLA TIDGEISQDHINIVLNYLQYHVDKQDGFVQPRNFLSADSPDLA-------KGQIMERLQT ELAVASAQELLQRMTDKCFKKCIVKPGTSLDSSDQKCVAMCMDRYIDAVNLVTRAYTQRL QQESGRMMNRLFGRSKPKGPAPNLNDCISNIDSRGESVEKKISKLDQELAKYREQMKKMR DGPSKNMVKQKALRVLKQKRMYENQLEGMRNQSFNLEQSNYAIQSLKDTKXSVDAMKVGV KEYKKEYKNINVNNIEDLQDQLEDLTEQAGEIQEIMG----------------------- ------------------------------------------------XXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMATTDGKVNTTERTVK TVPFPPSHRLTMPEVFDQKGKPRPEALKQHFVLEGRVTEDVALRLINEGAVLLRQEKTMI DIEAPVTVCGDIHGQFYDLMKLFEVGGXPATTRYLFXGDYVDRGYL-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXX------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------QLVNLSCSSIPSFVVSITAATQALALIELFNAPNG RYKQDVYLLPKKMDEYVASLHLPAFDAHLTELTDEQARYLGLNKAGPFKPNYYRYXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXX--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----KSRLQIREEGILALYKGVTPILLRAFPANAACFLGYE-------XXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXX--------LVECDAAMKQFLLHLDDTNALGRKFVLQDLDET HLFIQADIVDTLQNRIDDLMDKLHF----------------------------------- ------------------RRKKRIEKQLQQIDGTLSTIEFQREALENASTNTEVLKVMGD SAKALKQAHKNMDVDQVHDMMDDIAEQQEVANEIXKLSQIPIGFGQDMDEDXLMAELEEL EQQDLDEALLEVGNLPSVP---------------XXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXASYEATRPNLAINKNTKVICQGFTGKQGTVHSQQAI DYGTNMVGGVSPGKGGKTHLNLPVFNTVQEAKDATGADATVIYVPPAFCYKAIIEAIDAE IGLIVVITEGIPQQDMVRVKHKLLRQDKSRIIGPNCPGIIKPGECKLGIMPGHIHKQGKI GIVSRSGTLTYEAVHQTTMVGLGQTLCVGIGGDPFNGTNFIDCLDTFLKCPDTEGIVMIG EIGGQAEERAAEFLKXYNGANAKPVAAFIA------------------------------ ----------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFQRYVEIGRVAYVA FGPDAGKLVAIVDVISQNSVLVDGPCSGVVRKAMNLKQLHLTKFTLYPHSARTAVVKKAW EKAEVDRLWAETTWAKKIANREKRAALSDFDRFKLMKAKQ------------------KT CPLLLRVFXNTGRHHNMHDYSRGNTPATELQIYTWLDATLKELTSLVKEVNXDARKKGTF FDFAIVYPDTRTPVYRMREIGTTCSGRKGADDTVSLSSRRFQIGDYVDIAITPP-GLGKR LQTIXVAGYMKHYRNIGSPHXIIVPKSTLQNWMNEIKRWVPSLKAICLIGNQAERDAMIR DVILPGEWDICVSSFEICIREKSVFKRFNWRYIIIDEAHRIKNEKSKLSEVVREFKSTNR LLLTGTPLQNNLHELWALLNFLLPDVFNSADDFDAWFNANXCLENEQLVQRLHEVLRPFL LRRLKSDVEKRLXPKKETKIYIGLSK---------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------MEYAAVFWERCNDVTDVDRIIAQIERGEAKIQRRISIKKALDAKMARYKAPFHQ LRIQYGTXKGKNYTEEEDRFLICMLHKLGTDKENVYDELRAAVRQAPQFRFDWFIKSRTA MEIQRRCNTLITLIERENMEMEEKDKADRKK----------------------------- ------------------------------------------------------------ ------------------AKLRVACRICKGDHWTTRCPYKDTLAPIQDILGGGGKYVPPS MRDGGNKRGESMSXDEMATIRVXNLSEDTRESDLQELFRPFGNISRIYLAKDKVTGQSKG FAFINFHRREDAARAIAGVSGYGYDHLILNVEWAKPSXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------AGTYIRTLCVHLGLMLGVGGQMQELRRVRSGIQSEKDQLVTMHDVMDAQWLYD KHKDEEYLRRVIKPLEALLVSHKRIIIKDSAVNAVCYGAKIMLPGVLRFDNNIEINDNIV I-KXKGEAVALAIAQMTTAVISTCDHGIVAKIKRVIMERDTYPRKWGLGPVASKKKEMIS KGLLDKHGKTNEKTPKDWMGGYVDY-----------------------MAEVGWDRKTKP KTGQLKSEQALSQAQRQGVEIDTSKKYSAGQNKQHSVDKNTAKLDRETEELSHAHVTLDV GRIIQQGRQAKNLTQKELATRINEKPQVINDYENARAIPNQAILAKIERIIGIKLRGKDK GKPL---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXMDVFLMIRRGQTTLFMDAKETTTVLELKKMIQGISKKAPED IRLYKDNKNLGDCGFTSSFARAQAPATIGMAFRDFEELQIAPLSTPPELPDVMKPQESSS QHGSEHLYRYQAVLLRQRFEENKN-DPVEAKRVLEAAEEELFWKRHPQPYKFADAPGGSA YGREQYIPDWNYDLWHPLEKAQYPEYFAKREQRKAEYVQEWE-------XXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------------- --------------------------------VQKPVIYDIRARPTSVPTVTGSKDLQNV NITLRVLFRPMAAQLPNIFKTLGVDYDERVLPSIVNEVLKATVAQYDASELITQRELVSS KITAELTNRSEQFGIILDDISITHLSFGREFTEAVESKQVAYQEVEKAKYVVEREEQRKK AAVIRAEGDSSAAGLIAKALKEGGEGLIELRKVEAAEDIAYQLSQSPNIVYLPEKQNTLL QMPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XX-------------------------KRKKPDPQNLTVRDLPKASSALFFSYNTQLGPP YHIIVDTNFINFSIKNKLEIVSSMMDCLYXKCIPYVTDCVMAELE--------------- ------------------------------------------------------------ -----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXX------------------------------------------------- -------------------------------------------FVRHRTQDEIDREAQVD IGGLRDPEHDVDRAQDPKYLVLIGICTHLGCVPIANAGEYGGYYCPCHGSHYDASGRIRK GPAPLNLEVPKYTI-DGDIVTVGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXX------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------WWALGVLVY EMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVN DIKNHKWFATTDWIAVYQKKLEAP------------------------------------ -XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------MRRVLVGHRAAVNVVDFDHKYI VSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGMCL RVLEGHEELVRCIRFDNKRIISGAYXGKIKVWDLAAALDPRVPSASELVS---EHSGRVV PLXFDELQIDASSHDNT--------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXX-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------LKIVDVSYGGENGFNQAIELSAESLSNVK FIQEKKLIGKYFDEISQETDKYCFGVDDTLKALEMGAVDILIVWENLDIQRYVLKNHSQD EEKILYLKPEQEKDKTYFVDKDTGVELELVESMPLLEWFANNYKAFGATLEIITDKSQEG AQFXKAYGGSWRILRYKXDFQSLEPDEDDLIDYDLD--XXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------GEWVYCIGEDMVLYCFSVTTGKLERTLTVHEKDVIGLSHH PHQNLIATYAEDGLLKLWKP----------------------WKYARVEMAPPAEIPKAQ EQFLKILQARTGAWKNITVQQATVIGVEIACWFFVGECIGKRSLLGYQIPGILNNHVEXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXX--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------APEIMLNSKGYSKGIDVWSVGCILAEMLNNRPIFP GKHYLDQLNLILGVSGSPSAEDLSCVLNDKARGYLKSLPFKAKVPWTKLTDPKALDLLDK MLTFNPHKRITVEEALALR----------------------------------------- -----ELTPPKTTPDGNKVRQKLFGGFSLLLWIGAILCFVAYSIQASTDEDPPGDNLYLG IVLTGVVVVTGIFSYYQEAKSSQIMKSFKNLVPQFALVVRNGEKLNVRAEELVVGDVVEI KFGDRVPADVRVISAHGFKVDNSSLTGESEPQTRTPEFTNDNP----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------QRKVLEYT CHTAFFVSIVVVQWADLCICKTRRNSIIHQGMLNHHLTFGLFFETALAAFLCYCPGLDKG LRMYPMRFTWWLAPLPFSLAIFIYDEVRKMILRRHPGGWVEMETYYGFKKLSKGKKAVVG ATAGMIGTATALTDLELHAPKFPWSHKPILNSIDHASARRGYQVYKQVCAACHSMKYMYY RNLVGTVLTEEEARAEAAEAQILDGPDETGAMFKRPGKLSDRFPDPYDNDEAAKAANNGA LPPDLTFIANAREQQEDYIFALLTGYYDAPAGVTVGEGQAYNPYFPGGAIGMPQQLYNEG IEYDDGTPVTVSQQAKDICTFLRLSAEPEHDQRKRVGMMLMTLSAFVISYYYKRHKWASH KAMKIAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------ ------------------------------SGASYKGPVENNRRTGRGLFIWSNGAQYEG EFCDDVRSGSGKQIWPDGAEYXGEFVNDQRHGQGRHSWPNGERYNG-------------- ----------------------------------------------------------XX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------GYEDPMFTELMRLYLTIHSDHEGGNVSAHTCHLVGSA LSDPYLSFGAGMAGLAGPLHGLANQEVLVWLTGVMWTQESLKEFVWNTLKAGGVMPGYGH AVLRXTDPRYTCQREFALKHLPDDHMFHLVSDLYQIVPDILLEQGKAKNPWPNVDAHSGV LLQYYGMTEMNYYTVLFGVSRALGCLSSLIWDRAFGLPIERPKSMST--------XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXX---------------------------------NYPVGHERAAVMPILDIA QRQHGWLPISAMNKIAAMLKMPEMRVYEVATFYTMYNREPVGKYFVQICTTTPCLLGGCG SDIILETIKKNLGIEPGQMTKDKMFSLLEVECLGACVNAPMMQINDLYYEDLTPEDTDQI LNDLKAGKTPTPGPRSGQGGRFASEPAGGLTSLTSPP-----------XXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXX------------------------------------------ ------------------------------------------------------------ ---------------------------------LFSPNEHFTNSVLTKEYIIRSDPDPDD PFSFEGPEIIKCKGCTIDWNKGKNVTVKVIKKVQKHKGRGTKRTVTKTVQNDSFFNFFSP PEVPEGEMDDDNDAILAADYEIGHFIRERLVPRAVLYFTGEALEEGEEGEEEEDEIILLK EGTDTSQGKPQLVSNINACSAITDAVRTTLGPRGMDKLIVNSQGKATISNDGATIMKLLD IVHPAAKTLVDIAKSQDAEVGDGTTSVVLLAGEFLKQSKPFVEEGVHPQIIVRAFRRATQ LSVQKIREIAVNINKNPQEQKDMLFKCASTALSSKLVARQKDFFAKMCVDAVNILDDLLP LEMLRLPRHTG---------EGVAFKKTFSYAGFEMQRKLFDNPKIAILNVELELKSERD NAEVRVDNVKEYQAVVDAEWTILYDKLEKIHQSGAKVVLSKLPIGDVATQYFADRDMFCA GRVPEEDLKRTMKACGGSVQTTVSGLTLGTCQVFEETQIGG------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------KRNNIVPNVHFHKDWQ TRVKTWFNQPARKERRRQNRAKKARAIAPRPVGGNLRPIVRCPTIKYNTRIRSGRGFTIE ELKNAGINKKQAATIGIAVDYRRRNKSVETLQQNVQRLKEYKSKLIIFPKKLSKPKKGDA TEEELKLATQLTGEVLPVTQSFKSEKARAISEEEAKFSAFNKLRQERAHARLRGYREKKA REAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------- ------------------------------------------------------------ ------------------------------------------------------------ ---FKQLKASDWSRVVIAYEPVWAIGTGKVATPQQAQEVHKALRKWISENVKADVAKQVR ILYGGSVTADNCKELASQPDIDGFLVGGASLKPDFIKIINAKEREGLLDPAWGKTQKKTF TAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGEQLPKPDRGKMRFHKIANVNKDT TVYRKQRSKTVSIGAEEIVDGNLKMTLGMIWTIIVQNFHLSWKDGLAFCALIHRHRPEFA GLLQVVPDNPL------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------EDAKVGTATVKAGIPKGCMGLDVGPESSKXFE AVILKSKTIVWNGPPGVFEFPNFAKGTKSMMDAVVKATGKGATSIIGGGDTATCCAKFNT EDKVSHVSTGGGASLELLEGKNLPGVAALTDAXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXX---------------------YKYWDVPPPGXEHITPMQYKAMQAAIP FAGSAISRQARRLYVGNIPFGVTEEMMMEFFNGQMKMTSLTQAEGNPVIACQVNLDKNFA FVEFRSVDETTQAMAFDGINFQGQSLKIRK------------------------------ -------------IRELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDQACAGLNGMQLG DKKLIVQRASVGAKNAAQAPVQLQIPGLNVSDVXTEVLCLMNMVTPDELEDXEEYEDILE DVKEECGKYGIVKSIEIPRGIKGVEVPGVGKIFVEFNSVIDCRKAQQALTGRKFANRVVV TSFFEPDKYHRREFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRLKGQIPDIKSSL DIVKHMQKKKDTVQTKFQMADNLFVKATIPPTDKVNLWLGANVMLEYTLDDAEALLTKNA AEKSLETVEKDLGFLRDQTTTIEVNMARVYNWDVKRRQAAKA-ADNALARAGLHFDELNK IRVLEPEVAAQTTELKDETKEFLDKLSEFQRIVSSFIAVVDEVGGEVEKEKMKAIGSRNL LKSVAKQREAQQQQLQALITEKSIQLERLRIQHESLQKEEKDQIEFIEQ-----XXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX -----------------RPRRGAVSAEVYTEEDASSYVKKVXPKDYKTMAALSKAIAKNV LFAHLDDNERSDIFDAMFPVHRHAGEVIIQQGDEGDNFYVMDQGEVDVYVHNDWVSTIGE GGSFGELALIYGTPRAATIKAKTDVKLWGIDR---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXX---------------------------------LRQKRLQAL KKQATQKQEWAALGHGKYEELKEEPEFFKAGQQSKRMVCHFYRDGFFRCKIVDKHMGLLA QKHHETRFCKINAEKSKFLVDRLNIKTLPTICLVRDTKTVDYIVGFTDLGNTDEFSTEML EWRIAQADCIHYSGDLLTPPTQTDKKKTIRGRDDDDXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXTVRPENPLRQKTLEDFGRYVGECLPRFVQKVQVSTHGELDLLIHPDGVEAVLXFLKE HHNAQFENITDITAVDVPTRQCRFEIVYILMSLRYNARIKVKTYTDEMTPLPSIVGIYRG ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------SINLPHIAAGFDQEAAAVLMSRVAVFRAE TDDGPDVLRWLDRMLIRLCQKFGDYHKDDPNSFRFSEQFSLYPQFMFHLRRSQFLQVFNN SPDETSYYRHCLLVEDLTQSLIMIQPILYAYSFNGP------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CQKKCVPXKYKEADLSKGESVCLDRCVAKYMEIHDRIGKKLT AMSVQDEETAKKIQ---------------------------------------------- ------GEEVQIDILDDYAAIRDNYFRSGEGFLCVFSITEQESFQSTSEFREQILRVKSD ENIPFLLVGNKADLEEKRQVSAEECNQRASQWGVPYVETSAKTRANVDKVFXDLMREIRS RKLEKKKSKKKCVILXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXPLRVLITGAAGQIAYSLLYSVAKGDVFGANQPISLVL LDIVPMMGVLNGVVMELQDCALPLLTEVVPTSDGEEAFKDIDVAILVGAMPRREGMERKD LLKANVKIFRAQGEALDKVAKKSVKVVVVGNPANTNCFILKKYAPSIPAANFSCLTRLDQ NRACAQIAMRQDVNNVIIWGNHSSTQFPDVSKATVAKEAVKDDAWLQNEFISTVQRRGAA VIAARKLSSAMSAAKAICDHLRDWWHGTPQGAIASMGVVSDGYGIEAGMIYSFPVQIDRT YKIVQGLAVDDFARAKMDFTLKELRE---------XXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXX---------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------ILDTINIFIRIAMMLAGGG NRKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------GLFYMDHDLVKRNLEKGXTLIEEGGDWDRRNRLKVYKGLY SMAIXDFKTAANLFLDTVATFTSYELMDYKTFVRYTVYCCMIALERPQLREKVIRGAEIL EVLHSLPDVKAFLFSFYNCQYKEFFAALSKVEDYMKGERYLEPHYRYYMREMRIHAYSQL LESYRSLTLNYMANSFGVTEDFIDRELSRFIAAGRLHCKIDKVGGIVETNRPDSKNWQYQ ESIKKGDLLLNRVQKLSRVINI-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AMNRSLPNVILGGYGTSSTGT GEAMKVTGTHTEVNVDETVEKMVEANDIMIVPGYGLCVAKAQYPIAELVKLLTDKGKKVR FGIHPVAGRMPGQLNVLLAEAGVPYDQVFEMEEINDDMPEVDLTLVIGANDTVNSAAEED PNSIIAGMPVIRVWLGKE------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------MLEIEGPVCMCQGPCCTGDQEFIVRSSDVGKISKQWSGYVK EYFTTADNFGVSFPMDLDVKMKSVMIGAVFLI----------XXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLARNCSKIAPQAKHR GYAEMSFTFASPAKVVVKQVDVPSSTGNFGILASHVPLLAVLRPGVV------------- ------------------------------------------------------------ -------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------RLGEPDEFAHTVQYIVENPLINGEVIRVDGALRQR NFSFRVHGRNTSAKSEVSRDYPLVEHEYDAVVVGAGGAGLRAAFGLANQGYKTACITKLF PTRSHTVAAQGGINAALGNIEEDKWEYHFFDTVKGSDWLGDQDAIQYMCEEAPQAVIELE NYGMPFSRLESGKIYQRAFGGQSIDFGKGGQAHRAC------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------PEQLNARLPGISETAMIFAGVD VTRDPIPVLPTVHYNMGGVPTNYRGQVIDTNGEDKVVTGLWAAGEAACVSVHGANRLGAN SLLDLVVFGRACANNIADVTKPGDKLPEVKSNAGEESVSNLDKIRFAAGSXPTADMRLRM QKTMQTHAAVFRDGPTLDEGCSKLNALWEE------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------EFMSEMKKFDAEDDLGFPDD DEESQGSAMAQAASGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHD HPDVATMLNILALVYRDQGXYKDAGSLLHDALNIREXTLGRDNPAVAATLKQLSVIWKSV AKYKXPKPLCKRTGKSEKKVLGXDHPDVAKAATNLALLCQKKAKYEEVEHY--------- -----------------------------KLAAKWDSDAEAEIIGWFQQLLQPGMREIEK QLRDGILLAKLANVVAAKKMKIKVNTLSAPFKQME------------------------- -------LVLNCIITLGTETQRNGFNGPTXGPKPVEKNVRNFSEEQLKAGHLQAGXNKCA SQSMGGVRHVADIRADDFXQSGSAVIGLQAGNKGASQSGMSIGGVRHVADIRADDFDKSG QSVIGLQAGSNR-----------------------------VIGLEAGSNKGASQSGMSI GGVXHVADIRADDFDSGQSVIGLQAGTKKXASQSGMSIGGVRHVADIRADDFSGQSVI-- ----------------------------------------------------------MP ETHNFGSAPITCHAYNASRNQLALPNNHEVHIYEMQWAKTATLAEHVQRVTGIDWAPRSD TIVTCGADRNAYVWPTLVILRINRAATCVKWSPNEDKFAVGSGARTISVCYFEKENDWWV SKHIKKPIRSTITCLDW------------------------------------------- ------------HXVSFSASGEKLAWVGHDSSVCMARARYKTQFLPFISCCFVTENRVVV AGHDCCPMLFSDEGGTIRFIAKIDSTKFSAMKHFRDIDKKATELHTQHQNTISQVSLYQG SKANCQRFSTSGVDGKLITWD--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------------- ------------------------------------------------------------ ----------------------------------------QFGGKRPFGVSILYAGWDRH YGFQLYQSDPSGNYSGWKATCIGNNSAAAVSMLKQEYKQEELDLDGAVALAVKVLSKTMD TNK--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------SLSDKMASLQDTADARKSKLIDNSAF LQFIWKTDVVESWIMDKETQVNSDDYGRDLSSVQTLLTKQETFDAGLQAFEKEGIQTITT LKDQLVASNHAQTPAIESRYQDVITRWQKLLGDSDARKQRLLRXTAKYRQVEDLYLTFAK KASAFNSWFENXEEDLTDPVRCNSVEEILALREAHEQFKASLSAAEADFNQLAELDKQIK SFNVXPNPYTWFTMEALEDTWRNLSKIIRERDEELAREQQRQEENDVLRKQFAQAANAFH AWLTDTRSAMMEGTGSLEAQLEATKKKSVDVRAQRSQLKHIEDLSAAMEERLILDNRYTE HSTVSLAQQWDQLDQLGMRMQHNLEQQIQACNESGVSEDALKEFSMMFKHFDKDKTGRLD HQEFK------------------------------------------------------- ------------------------------------------------------------ --------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------- ------------------------------------------------------------ ----------------------KMYAPEIGDFVYITDNAYTKDDIRSMERLILEVLDFQL GRPLPLHFLRRNSKAGEVDATTHALAKYLMELTVVEYEMVHVRPSEIAAASLCLAMKLLG WSHTLVHYSKYSEQQLLPVMRKMAKYALKKLTAVHTKYKTSKSLRISLIPELKSPLIQEL AXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGTALSVLG DRTTGQSIRTQNVMAASSIANIVKTSLGPVGLDKMLVDDVGDVTITNDGATILKLLEVEH PAAKVLVELAQLQDQEVGDGTTSVVIIAAELLKNADDLVKCKIHPTSIISGYRLACKEAC KYIQEHLTVSVDDLGRDCIVNAAKTSMSSKIINADAEFFANMCVDAATAVKTPDNKGGFR YPIKAVNVLKAHGKSARESVLVNGYALNCTVASQAMVKKVANPKIA-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---DDESARLLVAKSVLNEMVVEGKDLTVEYTIYNVGGSAALDIQLNDASFGQY-FEVVS GSLSGKWSRLSPGTNVTHAVILKPLEAGYFNFTSAEVSYLPGEEERVFGYSSAPGEGGIM XFREYDRRFSSHVVDWAAFAVMTLP------------------------XXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXX------------------------------------ ------------------------------------------------------------ -----------GGCEVAMMCDIIYAGEKAKFGQPEITIGTIPGAGGTQRLTKAIGKSRTM EMVLTGVPINAQEAEKSGLVSKVFPPDQLVDEAVKTAEKIANHSKIIVQMAKESVNASYE LTLNEGLRFEKRMFHATFATEDRKEGMTAFVEKRAPEFKD >Ridgeia_piscesae MSERKAVIKNADMTEDMQQDAVDCATQAMEKYNIEKDIAAYVKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAVLLFKSGFNTQLREFQTSVTQKDIDQAAKYIGAGAATV GVAGSGAGIGSVFGSLVIGYARNPSLKQQLFSYAILGSALSEAMGLFCLMMAFLILFAFX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------- ---------------VINCADNTGAKNLYIISVKGIKGRLNRLPAAGVGDMVMATVKKGK PELRKKVHPAVVIRQRKSYRRKDGVFLYFEDNAGVIVNNKGEMKGSAITGPVAKECADLW PRIASNAGSIRKGKTQKVVLGPNVMEGENVFGVAHIFASFNDTFVHVTDLSGKETIVRVT GGMKVKADRDEASPYAAMLAAQDVAERCKALKISALHIKLRATGGNRTKTPGPGAQSALR ALARAGMKIGRIEDVTPIPSDSTRRKGGRRGRRL-------------------------- ---------WKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP RNGCLNYIEENDVVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKQKKERPRSXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------------------- ----------------------------------------------DVALHDLESWTNRL LPSRQFGFLVLTTSGGIMDHEEARRKHLGGKILGFFFXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXX---------------------------------------------------- ------------------------------------------------------------ ---------------------------------------AFRNIKSIAECLADELINAAK GSSNSHAIKKKDELERVAKSNR-------------------------------------- ------------------------------------------------------------ --------------------------DKTIKLWNTLGVCKYTIEDGHTEWVSCVRFSPNT QNPIIVSCGWDKLVKVWNLTNCKLKTNHYGHTGYLNCVTVSPDGSLCASGGKDGQAMLWD LNEGKHLYTLDGGSIINALTFSPNRYWLCAATGPSIKIWDLEGKIVVDELRQEVISTSAE PPQCISLAWSADGQTLFAGYTDNLIRVRQVSMAA-XXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------- ------------------------------------------------------------ ----------QRRILPKPTRKSRRKNKQKRPRSRTLTSVHDAILEDVCFPAEIVGKRIRV KLDGSRLIKVHLDKSQQTNIEHKLDTFRAVYKKLTGKDVAFEFPEFVLXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXMKLNKLVSSSRRKNRRRHFQAPSHIRRKIMSSPLSKDLRQKHKVRSIPIRKDD EVQIVRGHYKGQQVGKVVQVYRKKFVLHIERIQREKANGASVNVGIHPSKVVIVKLKMDR DRKSILERKSRARISGKYTEESAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXX-----DKWHKRRSTGGRMKTIRKKRKFELGRPAANTKLGP RRIHTIRTRGGGKKYRALRLDAGNFAWGSEAQARKTRIIDVIYNASNNELVRTKTLVKNC IVQIDAAPFRQWYEAHYATPLGRKKGTKLTEAEEAVLSQRSKKTQKKYDERKKDSKVDAA LEDQFITGRVLACVASRPGQCGRCDGYILEGKELEFYLRKVKAKKGKXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRVRTK TVKKAARVIIEKYYTRLGSDFHTNKRVCEEIAIIPSKKLRNKIAGYVTHLMKRIQRGPVR GISIKLQEEERERRDNYVPEVSALDEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------- ---------------------------------------------EKIAVHCTVRGALAE EILEKGLKVREYELRTNNFSVTGNFGFGIQEHIDLGIKYDPNIGIYGMDFFVVLGRPGFT VSKRKRRRGRIGPQHRIKKDDAMKWFQQKYDGVILPGKXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX -----------------------------------------RYDRKQSGYGGQTKLILRK KAKTTKKIVLKMECTECKYRKQLAIKRYKPFELGGDKKKKGQMIQF-------------- ------------------------------------------------------------ --------------------------------MPEGTIMCCL-EKMGNHGRL-XTSGNYA TIVSQNPDTKRTRVKLQSGAKRMIPLANRAM----------------------------- -----------PVEHPHGGGNHQHIGMASIVRRDTFAGRKVGLIAVRRTGRLRGSEKVNG KXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------GLLIPDGVNVQYKPAHGPLKAW MARQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XMTKGTSSFGKRHNKTHTLCRRCGSRSYHIQKKTCSRCGYPAARMRKYNWSEKAKRRRTQ GVGRMRHLKIVFRKFRNGFREGVQAKKRTQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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GIVVYRGCYFGFYDTLKPLVLGDDAGLLVSFMLGYIVTISAGLVSYPIDTIRRRMMMTSG QAVKYKGSLDCTMQIVKHEGVVSLFRGAGXNILRGVAGAGVLSGFDNSRSCTIPWRLXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXMVRGPRKHLKRLNAPKHWMLDKLGGVFAPRPSTGPHKMRECLPLVVFLRN RLKYALTYDEVKKIVNQRLIKVDGKVRTDKCYPAGYMDVISIERTGENFRLIFDVKGRFA VHEITPEEAKYKLCKEKKLQVGPKGVPFLITHDARTIRYPDPLIKVNDTIQVXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------ -------------------------------------------------KYLTKKYMKKN NLRDWLRVVATTKDTYELRYFQINNEEDEDED--XXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX >Ridgeia_sp MSERKAVIKNADMTEDMQQDAVDCATQAMEKYNIEKDIAAYVKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAVLLFKSGFNTQLREFQTSVTQKDIDQAAKYIGAGAATV GVAGSGAGIGSVFGSLVIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLILFAFM SHYKDAGKAPDVTIHRIRITLTSRNVKSLEKVCADLIRGAKDKNLKVKGPVRMPTKLLRI TTRKTPCGEGSKTWDRYQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADMDQVM QFIEPAKQFSKDSIRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNII V-----SKKRKFVADGVFKAELNEFFTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVL GEKGRRIRELTSVVQKRFSFPEGTVELYAEKVATRGLCAIAQAESLRYKLIGGLAVRRAC YGVLKFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGEPIGDYIDSAVRHVLLRQ GVLGIRVKIMLPWDPSGKIGPKRPLPDHVSIVEPKNDPNPSSPYSEQKGTK-SKRGRGGS SGGKFRISLGLPVGAVINCADNTGGKNLFVISVYGIKGRLNRMPAAGSGDMIIATVKKGK PELRKKXMPAVIIRQRKHIRRKDGVFIFFEDNAGVIVNNKGEMKGSAITGPVAKECAELW PRVASNASSIRKGKTQKVVLGPNVMEGENVFGVAHIFASFNDTFVHVTDLSGKETIVRVT GGMKVKADRDEASPYAAMLAAQDVAERCKALKISALHIKLRATGGNRTKTPGPGAQSALR ALARAGMKIGRIEDVTPIPSDSTRRKGGRRGRRLMGKPRGIRTARKMRTHRREQRWHDKD YKKGHLGTRWK------------------------------------------------- ---------------------------------------------------------DGT TTVRTRKFLTNRLLCRKQMVVDVFHTGRATVPKTEVREKLAQMYKTTSDVVFCFGFRTQF GGGRTTGFALIYDSLDFAKKLEPKYRLQRHGSRKQRKDRKNRMKKVRGTKKSKVGAXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXMGNMFERLFRSLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVGEAREELMRMLAEDELRD AVLLVFANKQDLPNAMNAAEITDKLALHSLRQRNWYIQATCATSGDGLYEGLDWLANQLK NQKMPLAKDLLHPSLEDEKRSCKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRRKQHMVRMNVLADALKSICNAERRGKRQVLLRPCSKV IVRFLTVMMKHGYIGEFELIDDHRSWKIVVNLTGRLNKCGVISPRFDVALHDLESWTNRL LPSRQFGFLVLTTSGGIMDHEEARRKHLGGKILGFFF-GRMHVPGKGISQSALPYRRSIA TWLKLSSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKKKGLAPS IPEDLYHLIKKAVAIRKHLERNRKDMDSKFRLILVESRIHRLARYYKTRRVLPPNWKYES STASALVA---------------------------------------------------- -------------------------------------------------LVTAVINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAVWLLCMGAREAAFRNIKSIAECLADELINAAK GSSNSHAIKKKDELERVAKSNRMTEQMTLRGTLQGHAGWVTQIATTPQFPDVLLSASRDK TLIMWRLTRDSSYGYPQKALRGHGHFVSDVVMSSDGQFALSGSWDSTLRLWDLNTAQTTR RFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIEDGHTEWVSCVRFSPNT QNPIIVSCGWDKLVKVWNLTNCKLKTNHYGHTGYLNCVTVSPDGSLCASGGKDGQAMLWD LNEGKHLYTLDGGSIINALTFSPNRYWLCAATGPSIKIWDLEGKIVVDELRQEVISTSAE PPQCISLAWSADGQTLFAGYTDNLIRVWQVSMAA-MREYKLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKVVEVDLQQCMLEILDTAGTEQFTAMRDLYMKNGMGFLLVYSIT AQSTFNDLQDLREQILRVKDMDDVPMILVGNKCDLEDERVVGKLSRKWNCAFMETSAKSK INVNDIFYDLVRQINRKNPDTMSEEKKEGSDHINLKVTGQDGSVVHFKXKKNTPLRKLMS AYCERTGVKMGSMRFRFDGQPINETDTPSQLEMEDGDSIDVFQQQTGGMATLPMNPKPFL NGLTGKPVMVKLKWGMEYKGYLVSVDGYMNLQLANTEEFIDGALCGNLGEVLIRCNNVLY IRGVEEEDEEGEMKDMSDAEGDDVPS--ISTGGMDINVALQEVLKNALIHDGLARGLHEC AKALDKRQAHLCVLANNCDEPMYVKL---------------------------------- -------------------------------------VRRKLVIVGDGECGKTCLLIVFS RDEFPEVYVPTVFETYVADIEVDNRQVELALWDTAGQEDYDRLRPLSYPDVHVIVMCFAI DNPDSLENIVEKWSPEVDHFCPNVPVILVGNKKDLRNDPAVHEELSKRKLKPVATEDALL VAQRIGAHAYLECSAKTRDGVRDI------------------MDDFQSSEETAFVVDEVS NIIKESIEAAIGGNAYQHNKVNQWTSNVVEQCLNQLTKLAKPFKYIVTCVIMQKNGAGLH TASSCFWDNSTDGSCTVRWENKTMYCIVSVFGLAIMFSANAKIIKPQGEKPDEFESSISQ ALLELEMNSDMKQQLRELTITAAKEIDVQGKKAIIIFVPVPQLKAFQKIETRLVRELEKK FSGKHVVFIAQRRILPKPTRKSRRKNKQKRPRSRTLTSVHDAILEDVCFPAEIVGKRIRV KLDGSRLIKVHLDKSQQTNIEHKLDTFRAVYKKLTGKDVAFEFPEFVL------------ -RGRGRGRGRGKE-EKEWVPVTKLGRLVKDGKIKTLEEIYMFSLPIKEFEIIDFFLDKVL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDHNGHVGLGVKCSKEVATAIRGAIVLAKLSV IPVRRGYWGNKIGKPHTVPCKVTGKCGSVLVRLIPAPRGTGIVSAPVPKKLLTMAGIEDC YT---GQTATLGNFAKATYAAISNTYAYTRPSWSRGPVFXKSPYQEFTDHLAKMSGGIDT LALKEDDVTKFLACGTHLGATNVDFQMLQYVFKRKADGIYVINLRKTWEKLLLAARAIAA IENPADVCVISARPYGQRAVLKFASYTGSTPVAGRFTPGTFTNQIQAAFREPRMLIVTDP RMDHQPVTEASYVNIPVIALCNTDSPTRYVDIAIPCNNKNNHSIGLMWWMLAREVLRLRG TILREQPWDVMTDLFFYRDPEETEKE---------------------------------- -------MKLNKLVSSSRRKNRRRHFQAPSHIRRKIMSSPLSKAHR------------DX SXXXXKXXXXXXQ--GXSAVCSAENCIHIERIQREKANGASVNVGIXPFKVVM------- -----------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXREGRKKKQVTHEVVTREYTVNIHKRIHGI GFKKRAPRSIKALRQFAEKMMGTPDVRIDTRLNKHMWSKGVKNVPFRVRVRLARKRNEDE DSPHKLYTSLYY----------------SSKSEFLVNGKYRLVRKIGSGSFGDIYLGINI SNGEELAVKLESHKARHPQLLYESKLYKILQGGVGIPHTRWYGEKDYNVLVMDLLGPSLE DLFNFCGRRFTMKTVLMLADQMIGRIEYVHNKNFIHRDIKPDNFLMGIGRHCNKVFLIDF GLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRGS LPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGYPAEFAMYLNYCRGLRFEEAPDYMYLR QLFRILFRTLNHQYDYVFDWTILKQKAA--MNAEKLKQRIGGKGTARRKRKVIHRTATTD DKKLLSSLKKLAVNNIPGIEEVNMIKDDGQVLHFNNPKVQASLAANTFAITGHAETKQIT EMLPGILNQLGAENLANLKKIATTAEEIDDDDDDVPDLVENFDEASKEEMVRYSLDPENA TKSAKARGSHLRVHFKNTRETAHNIRNMHLRRAVSYLKNV-SREECVXX----------- ------------------------------------------------------------ ------------------------------------------------------------ --------------DGSGTIDAKELKVAMRALGFEPKKEEIKKMISDIDKEGTGQIDFND FLTMMTLKMSEKDSKEEILKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQEADRD GDGEINEPEFLRIMKKTSLY---ARDKWHKRRSTGGRMKTIRKKRKFELGRPAANTKLGP RRIHTIRTRGGGKKYRALRLDAGNFAWGSEAQARKTRIIDVIYNASNNELVRTKTLVKNC IVQIDAAPFRXWYEAHYAHPSFGRQG---------------------------------- ------------------------------------------------SLVIPEKFQHIL RVMNTNIDGRRKVPFA-----------------------------LDEEGGGRLLTIMSN PATYKIPTWF-------------------------------------------------- -------------------GSGTDSDSEGSVPELEEMAAAAGLPEELVSRAKQSRSEKKA RKAMSKLGLKQI------------------------QSPASDTYIVFGEAKIEDLSQQAH DGVLQK-----------------------------------------------MGRVRTK TVKKAARVIIEKYYTRLTLDFHTNKRVCEEIAIIPSKKLRNKIAGFVTHLMKRIQRGPVR GISIKLQEEERERRDNYVPEQSAIEEIDPDTKDMLKLLDMHNIAGLQVTQPI---MKWEY KEEHTFDKRRTEGEKIRKKYPDRVPVIVEKAPKARVGDLDKKKYLVPSDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGALYQEHHEEDFFLYIAYSDESVYGXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMAIKFLEFVKPFCKVLPEIQKP ERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGIS PIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMVITVGQSIVYVMTGMYGDPAD IGAGVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVN TGRGTEFEGAVIALFHLLATRQDKVRGLREAFYRQNLPNLMNLMATIFVFAIVIYFQGFR VDLPIKSARYRGQQSSYPIKLFYTSNIPIILQSALVSNLYVISQMLATKFGGNFIINLLG VWADVASGGPARSYPVGGLCYYLSPPETLSHVLEDPVHAVLYIVFMLGSCAFFSKTWIEV SGSSAKDVAKQLKDQQMVMRGHREKSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIG SGTGILLAVTIIYQYFEIFVKEQGEMGGMSTLLFQTERAFQKQGNVFLNKKKLLVPRFYR SVGLGFKTPREAIEGTYVDKKCPFTGNVSIRGRVLSGVVIKMKMQRTIVIRRDYLHY--- ------------------------GDVAIVGECRPLSKTVRFNVLKVTKGAGAKKGFKKF XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------GIVAGGGRIDKPLLKAGRAYHKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGMASTVRRDTSAGRKVGLIAARRTGRLRGSKQVTG KXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRRPARCYRYCKINHTPRHTGDRXV--- KXRIL-IGREQG--NEFALCVHLVSDEYEQLSSEALEAGRICANKYLVKHCGKECITTSR TTRPHHIDRTTTRVVSRVSWRREQGVRGAFGKPQGXVARVHIGQPIISVRARENSKDSVI EALRRAKFKFPGRQKIHVSSKWGFTKWEKDEFTTMRGNGLLIPDGVNVQYKPAHGPLKAW MARQKVVKVLGRTGSQGQCTQVRVEFIDDTSRYIIRNVKGPVREGDVLTLLESEREARRL RMTKGTSSFGKRHNKTHTLCRRCGSRSYHIQKKTCSRCGYPAARMRKYNWSEKAKRRRTQ GVGRMRHLKIVFRKFRNGFREGVQAKKRTQMLDDKASVKELDQWVEQLSQCKQLTENQVK TLCEKAKEILAKESNVQDVKCPVTVCGDVHGQYHDLMELFQIGGRSPDTNYLFMGDYVDR GYYSVETVSLMVSLKVRYKERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDNQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHSNALTLVTRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRC GNQAAIMELDDALKYSFLQFDPAPRRGEPHVTRRTPDYFLMGAYKYMQELWRKKQSDAMR FLLRVRCWQYRQLSAIHRAPRPTRPEKARRLGYRAKQGFVVYRVRVRRGGRKRPVPKGAT YGKPTNQGVNQLKFQRSLQSVAEERVGRKCGA---------------------------- ------------------------------------------------------------ ----GIATGRLSEERKAWRKDHPFGFVARPTKNIDGTLNLMNWECAIPGKKSTPWEGGLY KLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSLLDEDKDWRPAVTIKQILLGIQE LLNEPNVKDPAQAEAYTIYCQNRGEYERRVREQALRFRDPSM-KSSRMLHHINYRMRCTL QDGRTFIGTFKAFDKHMNLILGDCDEFRKVKPKNAKQREEKRALGLVLLRGENLVSMTIE GPPQPEEGVARVPLPGAAAGPGVGRAAGRGIQSVVGLQGPVRGVGGPSQQIMQP-MRMPN AGPPQDLPSFKLVLVGDGGVGKTTFVKRHLTGEFEKKYIATLGVEVHPLIFHTNRGPIKF NVWDTAGQEKFGGLRDGYYIQGQCAIIMFDVTARITYKNVPNWHRDLVRVCENIPIVLCG NKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLTGDSNLEFVAMPA LEPPEVQMDPDMVAKYEQELVIAQHTVLPDEDDDLSEGIRQYYISKIEELQMVTTEKTQN LRRLEAQRNELNSKVRMLREELQLLQEQGSYVGEVVKPMDKKKVLVKVHPEGKFVVDLDK NIDINDVTPNSRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYDMVGGLDKQIKEI KEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ KFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSARLESGSGGDSEVQRTMLELLNQLD GFEPKQNIKVVMATNRIDILDSALLRPGRIDRKIEFPAPNEIARSDILKIHSRKMNLTRG INLRKIAEMMPGASGAEVKGVCTEAGMYALRERRVHVTQEDLELAVAKVMQKDSEKNMSI KKLWKLGFAENFALSGAAAVISKTAAAPIERVKLLVQNQAEMLKNGSLDKPYKGVVDCTM RTFRTEGLLPFWRGNLANCLRYFPTQALNFAFKDQVKAMFKQSKNDSYGVKFTKNVISGG VAGAMSLVFVYSLDYARTRLANDLKSSKKRQYNGMVDVYKKTMKSDGIAGLYRGFVISCV GIVVYRGCYFGFYDTLKPLVLGDDAGLLVSFMLGYIVTISAGLVSYPIDTIRRRMMMTSG QAVKYKGSLDCTMQIVKHEGVVSLFRGAGANILRGVAGAGVLSGFDKFKELYVSWRLMAD NSDLDRQIEQLRNCEVIKESEVKSLCAKVREILVEESNVQRVDSPVTVCGDIHGQFFDLK ELFKVGGDIPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRLTLIR----------- ------------------------------AVIDGKIFCVHGGLSPSIQTLDQIRAIDRK QEVPHDGPMCDLLWSDPEDTQGWGVSPRGAGYLFGSDVVAQFNASNSIDLICRAHQLVME GYKWHFNDTVLTVWSAPNYCYRCGNVAAILELDEHLQRDFTVFEAAPQEQRGKPQADYFL XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- -------------------GVVYRGKLVEAEDNMNCQMVNITVTYRDGRVAELENVYIRG SKIRFMILPDMLKNAPMFKKISAGRGKSAILRAAARGRGRAGG--SRGG----------- ------SASNRIIQAKDHASIQMNIAEVDPTTGRMTGQYKTYAICGAIRRMGESDDCIIG LAKRDGMIAKMVRGPRKHLKRLNAPKHWMLDKLGGVFAPRPSTGPHKTXK---------- ------------------------------------------------------------ ------------------------------------------------------------ ----KVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTA GQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADNNIVIMLVGNKSDL RHLRAVPTDEAKAFAEKNNLSFIETSALDSTNVETAFQNILTEIYKIVSQKQFPDSPEGN NVETIIVAPTDNTGGRGKKPCCMTSRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVAVR GRDLVVLGVERKAVAKLQEDRTVRKIALLDDHVALAFAGLTADARILISRARVECQSHKL TVEDPVTLEYITRYIAQLKQRYTQSNGRRPFGLSTLIIGFD------------------- ------------------------------------------------------------ ------------------------------------------RKYEPPVPTRVGKKKKKI KGPDAANKLPQVTPHTRCRLKLLKLERIKDYLLMEEEFIKNQERLKPQEEKQEEERSKVD DLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVGILSFVDKDSLEPGCSVLLNHKVHAVV GVLSDDTDPMVTVMKLEKAPQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIKSPK GVILYGAPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPS IIFIDEIDAVGTKRYDSNSGGEREIQRTMLELLNQLDGFDSKGDVKVIMATNRIDTLDPA LIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTLATDVNIEDYVMAKDDLSGADIKAICT EAGLLALRERRMKVMSEDFRKAKENVLYRKNEGTPEGLYLKRKPYSPFQGTNAMDYALAR TDDLINWGRKSSLWPMTFGLACCAIEMMHFAAPRYDMDRFGVVFRASPRQSDCIIIAGTL TNKMSPALRKIYDQMPEPRWVISMGSCANGGGYYHYTYSVVRGCDRIIPVDLYIPGCPPS AEALLYGILQLQKKIKRMNSIQMWYRKTDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYA NNSNYKNDTMIRKEAYVHKSVMEEMKRMIVD----------------------------- ---------------------------------------------------XXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMTEYKLVVVGAGGVGKSA LTIQLIQNHFVEEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGF LCVFAVNNTKSFEDINQYREQIKRVKDAEEVPMVLVGNKVDLPSRSVEMKQGKMLAESYL IPYVETSAKTRQGVDDAFYTLVREIRKYMGDRYNIHSQLEHLQSKYIGTGHADTNKWDWL TNQHRDSYASYLGHFDMLNYFAIVENESKARVRFNLMERMLQPCGPPPERPED-QIELCS FSGYKIYPGHGKKVVKADGRPFMFLSAKCEKSHAMKRNPRKINWTVLYRRKHKKGQQEEV SKKRTRRTTKFQRAITGATLSDIMAKRNQKPEVRKAHRRQAIRAAKEKQRVKE------- ---MKLNISYPATGCQKLVDIEDELKLRSFYEKRMGAELDAGCLGDEWKGYVVRISGGND KEGFAMKQGVLTAGRVRLLLSKGHSCFRPRRSGERRRKSVHGCIVDANLSVLNLVIVKKG EKDIPGVTDTTIPRRLGPKRASKIRKLFNLSKEDDVRQYVVRRPI-PRTKAPKIQRLVTP LVLQRKRHRLALKKHRAEKKREDAAEYAKLLAQRMKEAKERKIERRRSASASKKVKARDL RGKKKDDLEKQLGELKTELSQLRVAKVTGGVASKLSKIHIVRKSIARVLTVINQTQKENL RKFYKPKDLRAKKTRAIRRALTKYELSLKTKKMQRKQRLYPMRKYAVK------------ ----------------------------------------------------------FT RGDGTGGRSIYFADENFKLKHYGAGWLSMANAGKDTNGSQFFITTKKTEWLDGRHVIFGK ILEGMKVVRKVENTKTGQDKPAKDVVIADCGSLPVDKPFAVTKESAEE------------ ------------------------------NFKSKLIVQSDIAFSKRYLKYLTKKYMKKN NLRDWLRVVATTKDTYELRYFQINNEEDEDED--TKEEKGDEETKYGSCEGPDAMYVKLV SSDGHEFIVKREHALTSGTIKAMLSGPGQFAENEMNEINFREIPSHVLQKVCMYFTYKVR YTNSSTEIPEFPIAPEIALELLMAANFLDCTREITLAEVKEHTTAEDCWVAVDGKVYDLS DYIDIHPGGNESIEAEAGTEATKAYDFVGHSAYANKMMDQYQIGILVEVKK--------- --------------MSYMLQHLHNGWQVDQAILSEEDRVVIIRFGHDWDPTCMVMDETLY KVAEKVKHFAVIYLVDITEVPDFNKMYELYDPCTTMFFYRNKHIMIDLGTGNNNKINWAM EDGQEFIDIVETIFRGARKGRGLVVSPKDYSTKYRYKKLQRQLEFLEVQEEYIKDEQKNL KKEYLHAQEEVKRIQSVPLVIGQFLEAIDQHTGIVGSTTGSNYYVRILSTIDRELLKPSA SVALHKHSNALVDVLPPEADSSITMLQADEKPDMTYADIGGMDIQKQEVREAVELPLTHF ELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVR DVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTVNVKVI MATNRADTLDPALLRPGRLDR-VEFPMPDRRQKRLIXSTITAKMNLSDDVDLEDYIARPD RISGADINAICQEAGMQAVRENRYVVLPKDFDKGYKNNIKKDETEHEFYKSHPPVSLESI KERVLFVLNHYDKVDPEKLVVDSHFMNDLGLDSLDQVEVIMAMEDEFGFEIPDSDAEKLM RPADIIQYVADKEDITRRVQTMPDDLKNIEFETSEDVDVTPTFDGMGLREELLRGIYSYG FEKPSAIQQRAIRPIVKGRDVIAQAQSGTGKTATFSIAILQCLDTQFRETQALVLSPTRE LAGQIQKVILALGDYMSVQCHCCIGGTSIGEDIRKLDYGQHVVSGTPGRVFDMIRRRNLR TRSIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLLSATLPHDILEMTSKFMTDPI RILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKM REANFTVSSMHGDMLQKEREAIMKEFRSGASRVLITTDVWARGIDVQQVSLVINYDLPNN RELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLIMALRRP FDPAAHDLDPNFRLTKFAELKGGCKVPQEVLLKLLEGLQQASESEQSHFQYVAAVPRIGI GMDSCITPLRHGGLSLVQTTDFFYPLVDDPYMMGKIACANVLSDLYALGVTECDNMLMLL ALALKLTDKERDVVVPLMIRGFRDLAEEAGTSVNGGQTVKNPWMTIGGVATTVCQSNEFI MPDNAVVGDVLVMTKPLGTQVAVSAYQWLDQPDRWNRIKLVVSEDDVRKAYQRAMFSMAR LNRVAARLMHKYNAHGATDITGFGILGHANNLARIQKNEVGFVIHNLPVIAKMAAVSKAC GNMFGLLQGHSAETSGGLLIALPREQAAAFCKDIEKQEGYQAWIIGIVEKGNRTARIIDK PRVIEVPAKEKE----VLGTAEGYFITIDAHAEECFFDKVTSGTKMSLMFEVAEGGFLDI DVKITGPEGKSVYSGERESNGKYTFAAHSDGIYKYCFSNKMSTMTPKVVMFSMNIGEKPK ANHNKLEEMINELSVGLMGVKHEQEYMEVRERIHRAVNDNTNSRVVMWSFFEALVLVAMT LGQIYYLKRFFEVRRVVMAATLQPYLAAVRHTLTAAMCLENFSSQVVERHNKPEVEVRSS KELLLTPVVISRNEKERVLIEGSINSLRISISVKQADEIEKILCHKFMRFMMMRAENFIV LRRKAVADYDISFLITNVHTEQMYKHKLVDFIIHFMEEIDKEISEMKLAVNSRARISAEE FLKQFSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLV TMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTMPNTFKTLDSWRDEFLIQASPRDPEN FPFVVIGNKIDLENRAVSTKRAQQWCHSKGDIPYFETSAKEAINVEQAFQMVAKDALAQE KDTEMFNEFPDQIKLT----------TAAFDVRFPNANQTKNCWQNYVDYHRCHKIESYE PCEYFKRVYVGTSRTTLSGRW-------------MPDFLGKEQRKTNDDIEDEKPIQVLD EGDIALLKTYGAGMYSRSIKQIEDDIQDIMKKVNELTGIKESDTGLAPPALWDLTADKHT LHSEQPLQVARCTKIINADSDDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNK YQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVEMPLLHPERFVNLGI EPPKGVLLYGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMART KKACIIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDT LDPALIRPGRLDRKVEFNLPDLEGRTQIFKIHARSMSVEKDVRYELLARLCPNTTGAEVR SVCTEAGMFAIRARRKMATEKDFLEAVNKVVKAYAKFSATPRYMTYNMGAEKQHINIVVI GHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITI DIALWKFETNKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQT REHALLAFTLGVKQMIIGVNKMDNTEPPYSEARFEEIKKEVGQYIKKVGYNPETVAFVPI SGWHGDNMLKMSWFKGWKVTSGNTLMEALDNVLQPSRPTDKPLRLPLQDVYKIGGIGTVP VGRVETGIMKPGMVVTFAPCNLTTEVKSVEMHHQTLVQAEPGDNVGFNIKNVSVKDVRRG FVCGDSKNDPPMETDEFLAQVIILNHPGTIQAGYAPVLDCHTAHIACKFKELKEKIDRRS GKVLEANPQSVKSGDAAMVEMIPQKAMCVEKFSEYAPLGRFAVRDMRQTVAVGVIKNVKK REGGQGKVTKAAQKAELEQLRQEAEQLKNQIREARKAAADISLTQAAANVEPVGRIQMRT RRTLRGHLAKIYAMHWGTDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCSYAP SGSYVACGGLDNICSIYSLKTREGSVRVSRELPGHTGYLSCCRFLDDNQIVTSSGDMTCA LWDIETGQQTTSFTGHTGDVMSLSLSPDMRLFVSGACDASAKLWDIRDGMCKQTFSGHES DINAITVFPNGYAFATGSDDATCRLFDLRADQEIGMYSHDNIICGITSVAFSKSGRLLLG GYDDFNCNIWDTLKQDRAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKIWNMSYAYLF KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES FRSITRSYYRGAAGALLVYDITRRDTFNHLTSWLEDARQHASSNMAIMLIGNKSDLEARR DVKREEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYQKIQDGVFDINNEANGIKI GPQHSPTS-ASSPGGNQGGGMTRGRTELGDITVHNIKQLKRLNQVVFPVTYNEKFYQDVL EVGELAKLAYFNDIVVGAVCCREDRSQGQRRLYIMTLGCLAPYRRLHIGTVMLKHVLKIC EEDGNFDNVFLHVQINNDSAIKFYEKFGFEIVERKTSYYKRIEPADAYVLQKTFR-MPKQ IMEIKDFLLTARRKDAKSVKIKKNVKFKVRCSRYLYTLVIQDVEKAEKLKQSLPPGLGVK ELK-------------------------------------------FSGTVKLRHIPRPN MKVCVLGNQQHCDEAKANEVSFMDVDALKKLNKNKKLVKKLAKKYDAFLASDSLIKQIPR IVGPGLNKAGKFPVMLTHSESMMGKIDEVKATIKFQMKKVLCLAVACGHVNMGPEELQSN VQLAVNFLVSLLKKNWQNVRALYIKSTMGPAQRIYMADTDKLNIDSIIARLLEVRGSRPG KNVQLTENEIRGLCLKSREIFLSQPIMLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYEECKRRYN IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLSAGRPVTPPRNSSKNK GK-MFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEIIGTNVSTT YITCPAESKKTLGIKLPFLVMIIKNMKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPF ICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDEL PAEFKLYLPIQKEMTDTTIQNLQDPFADDNEIHIRIQQRNGRKTLTTVQGIRPDYDLKKI VKACKKEFACNG----------------------------------------SALFNFQS LLTVVLLLICTCAYVRALAPRMLDKNKEGLLGIFWKCARIGERKSPYVALSCIAMAVSIL FWSSGRITAALSRQLPRALNKRNALAAGFVANRKFSATSEVSSILEERIMGSPEANLEET GQVLSIGDGIARVYGLNNIQAEEMVEFSSGLKGMALNLEADNVGIVVFGNDKLIKEGDIV KRTGAIVDVPVGEDLLGRVVDALGNVIDGKGALTGKLRARVGVKAPGIIPRISVKEPMQT GIKAVDSLVPIGRGQRELIIGDRQTGKTAIAIDTIINQKRFNESLDEKAKLYCIYVAIGQ KRSTVAQMVKRLTEADAMKYTIIVSATASDAAPLQYLAPYSGCAMGEYFRDNGKHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDDFGGGSLTALPVIE TQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQIRAMKQVAG SMKLELAQYREVAAFAQFGSDLDASTQQLLNRGVRLTELLKQGQYVPMAVEDQVAIIFAG VRGHLDTMDPMLITKFEDEFITHVRSSHQDVLDTIRKETKISDETEAKLKKIVVDFLAGF MEAFYSIPFTVLECPNIKLKRPSWVATPSPMFVFALVLLSYFFVTAGVIYDVIVEPPSIG STTDEKGVSKPVAFMQHRVNGQFIMEGLASSFLFVMGGMGFVLLDQTNKPTTPKLNRILL LSVAFVCIAVSFFMCRVFMRMKLPMPKVRRSRKPPPDGWELIEPTLDELDAKMREVETDP HEGKRKVEGLWPIFRVHHQKSRYIFDLFYKRRAISRELYEYCLKEGIADKNLIAKWKKPG YENLCCLRCIQT------------------------------------EYAQVTKMLGNG RLEAMCFDGVRRLCHIRGKLRKKVWINQSDIILVGLRDYQDNKADVILKYTPDEARNLKA YGELPESAKINDD-GDEIIFEDIDDIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTLAK PKSEMTAEELSVREQEEFNTGPLSVLTQSVKNNTQVLINCRNNKKLLGRVKAFDRHCNMV LENVKEMWTEVPKMGKGKKKSKPVNKDRYISKMFLRGDSVILVLRNPLXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX- --------------------DQGAKHKQGPNLFGMFGNKTGQAPGYTYTDANKNRGIVWD TTTLDTYLENPKKFIPGTKMIFAGLKKKSDRDNLVAYLES---IFVERTLAIFKPDVVTD ELEEIILSAGFTILQKKRLVMTPEQASDFYAEHYGKLFFPSLVAYMSSGPLTVMVLAKAS AITYWRELIGPTNAVKARQTHPDSLRAIYGTDETRNGFHGSDSLYTADREIRFFFSDSIV EPIPRGQAARDYVAKTINPTLLAGLTALCKAKPINPVRWLADWLMEHNPNKPDV-MFEAR LVQGSLLKKVLEAVKDLLNEATWDCNSTGISLQAMDSSHVSLVSLMLRCDGFDTYRCDRN LSMGINLTSMSKIMKCAANEDAITIKAGDNADTVTFMFESPNGEKVSDYEMKLMDLDTEH LGIPETDYSCVIKLPAGEFQRICRDLSQIGESVVICCTXEGVKFSANGDLGTGNIKLAQT S----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --NEPPGARARVCLTGLTVAEYFRDEEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIA ELGIYPAVDPLDSTSRILDPYIVGQEHYDIARGVQKILQDYKSLQDIIAILGMDELSQED KLVVSRARKIQRFLSQPFQVAEVFTGTEGKLVPLKDTIKGFNMILKGELDHLPEVAFYMV GGIEEVIARAEKLAE--------------------------------------------- -------------------------------YLRDFLHLPPEIVPSTLKRQTGGEDRSQY RRGAEGDKKADAGAGATMGHSSSKLKPQELAELSRESEFSVEEIEQWYKGFLKDVPSGKL TIEEFKKIYGNFFPYGDASVFAEHVFRTFDKDNNNSIDFQEFICALSVTSRGKLEDKLKW AFNMYDL----------------------------------------KIFRQMDKDLDGK LSIEEFIEGAKSDPSIVRLLQCDP------------------------------------ --------------------------------------------GLIHARYIMTNRGIAQ MIEKWQQGDFGYCPRVYCENQPMLPIGLSDVPGESMVKLYCPKCQDVYTPKSSRHHHTDG AYFGTGFPHMLFMVHAEYRPKRPPNQFIPRLYGFKIHPLAYELQYQAASNFKTGYGN--- MTNTKGYRRGTRYMFSRAFKQKGRTPLSQFMIVYKRGDIVDIKGNGAQQKGMPHKSYHGR TGRVYNVTPHAVGVIVNKRVKG-------------------------------------- -------------------------------------ASRTFWKQVSPPDPSYEWRDMTD KAANTIFILEICKGLGITLSMLFKEPATLNYPFEKGPLSPRFRGEHCLRRYPSGEERCIA CKLCEAICPAQAITIEAEPRADGSRRTTRYDIDMTKCIFCGFCQEACPVDAIVEGPNFEY STETHEELLYNKEKLLDNGDRWEPEIAANLQADYLYR------------KNNHETDKEQQ EAIEQIDEVQNEIDRLNEQASEEILKVEQKYNKLRQPYFQKRSELIGKIPNFWVTAFVNH PQVSALLNEEDEEALQYLSKVEVQEFEDIKSGYKINFHFDENPYFENKTISKEFHLN--- ------------------------------------------------------------ -----------------KKLTKKEELLLQDFSRNVSTKSSALFYGNAFIVSAIPIWLFWR IHQMDPYILFGIVTLVCTYLIAYAYKNVKFLLKHKIALKRSEAVTREVMRKVADDKKMAK QEKDERILWKKNEVADYEATTFSIFYNNALFLLFIVLMSFYILRSLSPAVNYTASMATAG GLLALFSTSSKPGQGKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQT VCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFARAKTWVKELQRQ ASPSIVIALAGNKADIRMVEFDEAQAYAEENSLLFMETSAKTAMNVNDIFLAIAKKLPKT DLGVDLNQDNMAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTILLQN LYINPQNTAQIHVSDVEMQAHYDGFFEEVFVELESKYGEIEEMNVCDNLGDHLVGNVYVK FHREESAEKAVADLNNRWFNGRPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKP ISHELRRELYGRNRRSRSRSPPTRRSRSRDRRHHRHRSRSRER--MFLTRSEYDRGVNTF SPEGRLFQVEYAIEAIKLGSTAIGIQTNEGVVLAVEKRVTSPLIEPSSIEKIMEVDTHIG CAMSGLIADSRTMIDRARVEAQNHWFTYNERMSVESITQAVSNLAL----DDADPGAMSR PFGVALLFAGIDPKGPQLFHMDPSGTFIQYDAKAIGSGSEGAQQALQDTYHKSMTLKEAC KESLVILKQVMEEKLNATNVEMATVTPQRMFKMFSKEEIEGIIKDI-------------- ------------------------------------------------------------ -------------XALPVR-ARNRVNAQAQAYEYMAAYTESAKQVGRLENAIGWYHSHPG YGCWLSGIDVSTQMLNQQFQEPFVAIVIDPVRTISAGKVNIGAFRTYPKGYKPPDEGPSE YQSIPLNKIEDFGVHCKSYYSLDVSYFKSVLDCKLLSSLWNKYWVNTLSSSSLITNAEYT TCQVFDLAEKLEQSEAQLGRGGFMEKKSEDKLAKATKDGCKNTIEVIHGLMSQVIKDKLF NQTGGLPRRIIKETQRLQAEPVPGIVAIPDDSNARYFHVDVAGPKESPYEGGVFKLELFL PEEYPMSAPKVRFMTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPD DPLANDVAEQWKVNEAQAIEIAKQWTKRYA-ADNEILDYEEEDDHEAKDVKGTYVSIHSS GFRDFLLKPELLRSIVDCGFEHPSEVQHECIPQGILAMDVICQAKSGMGKTAVFVLATLQ QIEHVDGQVSVLVLCHTRELAFQISKEYERFSKYMNNVKIAVFFGGMPIKKDETVLKTNC PHIVVGTPGRILALAKTLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMF SATLSKEIRPICKKFMQDPMEVYV------------------------------------ ------------------------------------------------------------ ----------------------------------------------------PPTYADLG KAARDLFNKGYNYGFYKIEAKTKTINGVEFTSNGSSNHDSGKFAGSLETKYKWNEYGLTF LEKWNTDNTLGTEITIEDQLVKGLKLSFDTHFAPQTGKKSGKIKTSYKQEYVNLNCDVDF DFAGPTIHGAAVLGYTGWLAGYQMSFDKSKLARSNFAVGYSKDDFTLHTSVNDGTEFFGS VFQKVNKDLETGVQLNWTAGSNATRFGIATKYTPDCCSTFRAKVNNSSQIGLSYQQKVRD GVTMTLSTLVEGKNFNQGGHKIGLGLDFEADSVRERSLQDYRKXLLEHKELEARLKDMRE QLKELTKKYDKSENDLKALQSVGQIVGEVLKQLTEDKFIVKATNGPRYVVGCRRQIDKSK LKPGTRVALDMTTLTIMRYLPREVDPLVYNMSSEDPGDITYAQIGGLGDQIRELREVIEL PLMNPELFQRVGITPPKGCLLFGPPGTGKTLLARAVASQLEANFLKVVSSAIVDKYIGES ARLIREMFGYARDHQPCIIFMDEIDAIRRFSEGTSADREIQRTLMELLNQMDGFDALGQV KMIMATNRPDTLDPALLRPGRLDRKIEIPLPNEQARLDILKIHSAPIAKHGEIDWEAVVK LSDDFNGADLRNVCTEAGMFAIRNERDYVIEEDFMKAVRKVSDNKKLESKLDYKPVMPET ITTAVSKFYNEYMTSTSKKLKCIDAYLLYVMLTGIIQFLYFCLVGSFPFNSFLSGFISCI GSFVLAVCLRLQVNPQNKSEFLGIGPERAFADFVFAHIILHLVVINFIG----------- ----------------------------------------------------KLEQILLN GNNITMLVPGGDGPEVIDHYENPRNVGSMDKADTTVGTGLVGAPACGDVMKLQIRVDENG KIIDAKFKTFGCGSAIASSSLVTEWVKGKTLDEASAIKNTDIAGELSLPPVKLHCSMLAE DAIKAALQDYKVKREMLVLVLGDLHIPHRCNTVPPKFKKLLVPGKIQHILCTGNLCSKES FDYLKTLASDVHIVKGDFDENLNYPEQKVVTVGQFRIGLCHGHQVVPWGDTESLAMLQRQ LDVDILITGHTHKFEAFEHENKFYINPGSATGAYNALNSKIIPSFVLLDIQQSTVVAYVY QLVGDEVKVERIEYKKMVKFLKSGKVVLVLNGRFAGRKAVIVKNYDDGTTDKQYSHALVA GIERYPRKVTKRMAKKRIKQKSKIKAFVRVYNFNHLMPTRYSIVNLDKGVINKEAFKDPA RRQKAKREAKMKFEERYKSGKNRWFFQKLRFERTFIMIKPDAVQRGLIGDIIKRFEQKGF KLVAMKLVQASEEHLKKHYSDLSSKPFFGGLVKYMSSGPVVPMVWEGNVVKTGRIMLGET NPANSLPGTIRGDFCIEVGRNICHGSDAVESAKKEIDLWFSKEEQCQWKPSVEEWVYEXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------SKNVQNRGNVPKTLKS GEDEYPVGPFMIGLFLFVVCGSAVFQIIQSIMMXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMIRFI LIQNRAGKTRLAKWYMHFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIVYRRYAGL YFCICVDISDNNLVYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYSVVDEMFLAGEIRE TSQTKVLKQLLMLSSLEQPTIFSKIIDKSIPADIVYEDDLCLAFKDLQPTAPVHILVIPK KIIPGIPDDQQVLGHLLLVAKKVAEQKDGYRIVINNGMHGCQSIYHLHLHLIGGRQLNWP -MGGLFSYFTGLFGSKERRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVQYKN LKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSMDRDRIGISKQELVSMLEEDELKKSV LVVFANKQDIEGAMTVTEVANSLGLSIIKNRKYQIFKTSAIKGEGLDEAMEWLANTLQNA KGLYFHIAETEKKCFIEEIPDDTIVVGHYKVEIFDKAQNQYLPTVAGLGMHVEVKDPDEK IVLSRTYAADGRFTFTSHVSGEHVICLHSNSSAWFGGGQLRVHLDIQVGEHAVDYQQVAA KDKLTELQLRIRQLLDQVEMITKEQNYQRYREERFRQTSESTNQRVLWWAIAQTVILLST GFWQMRHLKSFFEAKKLVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXX-------------------------------------------------- -------------HLRVIWGKVTRPHGNSGCVRAKFRKNLPPKAMGRRIRIMMY------ ---------------------------------------------------------DTA GQERFHTITTSYYRGAMGIMLVYDITSAKTFDNISKWIRNIDDHANEDVVKMILGNKCDM EDKRQVPKEKGETIAREHAIPFLETSAKTNINVEKAFMDLAQAILNKXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXMSARPLITVYDEKGVATSSNVTLPAVFRAPIRPDIVNFVHFEMKKNGRQPYAV SEKAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKVWRRWHRH INIQQRRYAICSAIASTGIPSVVMSKGHRIEQVAEMPLVLCDKVEEIKKTKQAVGVLRKI NAWQEIEKVKNSRRFRAGKGKMRNRRRIQRRGPLIIYNQDNGITRAFRNIPGITLLNVAR LNLLKIAPGGHVGRFCIWTESAFKKLDGLYGTWRKPSSEKNGFNL--------------- ------------------------------------------------------------ ------------------SGEQELATKTLQIQSKRFYLDVKQNRRGRFIKIAEVGSGGKK SRLLLAMSTAAEFRDHLNDFSEHYASLGPPSPDSLPEDGKLKSEVMVKDNRRYYLDLKEN QRGRFLRVSPRSQQRSQIAIPAQGMIEFRDALTDLLDEFGTDDHEGQGELPEPRSMRVEN KMFYFDVGQNRRGVFMRVSETNFRTAITIPERSWARFRDILSDFVDK--------QMRAT INQKLVVSGERDKLKELLRTRLIECGWRDQLKQHCKEIVKQKGLEHVTVDDLVAEITPKG RALVPDQVKKELLQKIRKFLSEQ--MNIRNAKPDDLMNMQHCNLLCLPENYQMKYYFYHG LSWPQLSFVAEDEKGKIVGYVLAKMEEDPEDSVPHGHITSLAVKRSHRRLGLAQK----- ------------------------------------------------------------ ----MSHTILLVQPGRKPEGRTYSDYESVNECLEGVCKIYEEYLKRMNPNSPSITYDISQ LFDFIDQLADLTCLVYEKISSKYVPHNKAWIKEKIYILLRKQAGKMAEEG-EKKEQETKK VLHTYPLVRHSDMPDEMKTEAMELCVTACEKFSSNNETAAKMIKDTMDKKFGASWHVVVG EGFGFEMTHEIKNMMYMFFGGTTGILLWKCS-SHRKFSAPRHGHLGFLPKKRCKRIRGKC KSYPKDDRTKPVHLTAFLSYKAGMTHIVREVNRPGSKTHKKEIVEAVTILEAPPMIVAGI VGYIETPRGLRTFKTVWAGHLREEFKRRFYTNWCRSKKKAFTKYAKKWQDDMGKKEIEKD LAKMKKYCKVIQVVCYSQIKLLKKRQKKAHVMEVRLNGGSIAQKIEWAREHLEKQIPVGQ VFAQDEMIDVIGVTKGKGFKGVTSRWHPKKLPRKTHKGLRKVACIGAWHPSRVSFSIARA GQKGYHHRTEINKKIYRIGEGVHAKDGKVIKNNASTEYDITEKTITPMGGFPHYGEVNND FIMIRGCCVGPKKRVLTLRKSLLVHTKRIALEKVNLKMIDTTSKFGHGRFQTHQEKQNFM GPLKKDMQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLG LWDTAGQEDYDRLRPLSYPQTDVFLICFSLISPASFENVRAKWFPEVSHHCPSTPIILVG TKLDLREDKETVEKLKEKRLAPITYPQGLAMAKEIGAVKYLECSALTQKGLKTVFDEAIR AVLCPKPKPKKPHKCRLL------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---NVLRSYIKEYVTCHTCRSPDTILQKDTRLYFLQCETCGSRCSVASIKSGFQAVTGKR AAIRART-FDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGK DYSLHRLILGTHTSDEQNHLLIASVQLPNDNAQFDASHYDSERGEFGGFGSVSGKIEIEI KINHEGEVNRARYMPQNPCVIATKTPSSDVLVFDYTKHPSKPDPSGECQPELRLKGHQKE GYGLSWNPNLNGNLLSASDDHTICLWDINATPKEGRVIDAQTIFTGHTSVVEDVAWHLLH ESLFGSIADDQKLMIWXTRNNNTSKPSHTVEAHTAEVNCLSFNPYSEFILATGSADKTVA LWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHIWDLSKIGEEQSADDA EDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEEPDTPAA ELEMPAPSRARVYVDVNNHRPREYWDYESHVVEWGQQDDYQIVRKLGRGKYSEVFEAINI TNNEKCVIKILKPVKKKKIKREIKILENLRNGTNVIALVAIVKDPVSRTPALIFEHVNNT DFKQLYQTLTDYDIRYYLFELLKALDYCHSMGIMHRDVKPHNVMIDHDNKKLRLIDWGLA EFYHPGQEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPFFHGHDNY DQLVRIAKVLGTEELYEYIDKYQIDLDPRFNDILGRHSRKRWERFVHSENQHLVSPEALD FLDKLLRYDHQERLTAAEAMDHPYFYPIVKE---------------HNREKRQLMFKRAE KYVKEYRILDREGIRLAREARKHGNFYVPPQPKLAFVIRIRGVNGIHPRPRKVMQLFR-- ------------------------------------------------------------ ------------------------------------------------------------ ------------MQFLLLFSRQGKLRLQKWYGAQATKQKKKITRELITTILTRKPKMCSF LEWKDMKVVYKRYASLYFCVCIEAEDNELLTLEIIHRYVELLDKYFGNVCELDIIFNFEK AYFMLDELVLGGEVQETSKKNVLKAIAAQDLLQEEEPRGILEELGL-MSKAHPPELKKYM DKKLTLKLNGGRAVTGFLRGFDPFMNLVIDETVEESKTGEKNNIGMVVVRGNSIVLLESL DRIEFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTI RLQLWDTAG--------------------------------------------------- ------------------------------------------------------------ -----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFLDSFSFLDDVRRMDTRQLFYQ ALNFAMIVSSALMIWKGLMVHSGSESPIVVVLSGSMEPAFYRGDLLFLTNYKEEPVRVGD IVVFKVEGRDIPIVHRVLKVHERENGTVKFLTKGDNNSVDDRGLYAPGQLWLQKKDIVGR AKGFVPYVGIVTILMNDYPKFKYTVLALLGVFVLLHRE------------------DSGV GKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYR GAHGII-----------------------------------------------YTTAKEY ADQLGIPFLETSAKNATNVEQAFMTMAAEIKNRMGPVSTAQNVKINASTPVKQGGGGCCE DSLGEEVLRMNTDEIVSRTRLLDNEVKIMRSEVMRISHELQAQKEKIKENTEKIKVNKTL PYLVSNVIELLDVDPQDQAEEDGANVDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDPENL KPADLVGVNKDSYLILETLPQEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELIEAVVLP MTHKERFETLGIQPPKGVLLYGPPGTGKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGA KLVRDAFALAKEKAPAIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFMPNSD IKVIAATNRVDILDPALLRSGRLDRKIEFPTPTEEARARILQIHSRKMNVNPDVNFEELA RCTDDFNGAQCKAVCVEAGMIALRREATELCHEDYMDAIMEVQAKKKANLNYYAKDAADQ NFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRQDKRVKLQIWD TAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDNAQVVLVGNKC DLEDERVVSTERGKQLADQLGLEFFETSAKENVNVKAVFERLVDIICDKMSESLDSDPTQ TKRLTENPNPQNAGCQCLRTHKMAISRNYLAQPRLTYKTVSGVNGPLVILDDVKFPKFAE IVQLTLQDGTRRSGQVLEVSGSKAVVQVFEGTSGIDAKHTTCEFTGDILRVPVSEDMLGR VFNGSGKPVDKGPSVCAEDFLDIQGQPINPWSRIYPEEMIQTGISAIDGMNSIARGQKIP IFSAAGLPHNEIAAQICRQAGLVKLPSKSVQDDHNDNFAIVFAAMGVNMETARFFKQDFE ENGSMENVSLFLNLANDPTIERIITPRIALTMAEFLAYQCEKHVLVILTDMSSYAEALRE VSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQLPILTMPNDDITHPIPDLT GYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRDDHSDVSNQLYACYAIG KDVQAMKAVVGEEALSADDLLYLEFLQKFEKNFISQGAYENRTIFETLDVGWQLLRIFPK EMLKRIPAAKIAKYYPR--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXKPPYKVADIGLAEWGRKALTLAENEMPGLMMMRRVYGPQKPL RGARIAGCLHMTIQTGVLIETLLELGAEVQWSSCNIFSTQDHAAAAIAKRGVAVYAWKGE TDEEYIWCIEQSLVFPNGEPLNMILDDGGDLTNLVHTKYQQYLPSITGISEETTTGVHNL YKLMTKGLLKAPAFNVNDSVTKSKFDNLYGCRESLVDGIKRATDIMLAGKVAVVAGYGDV GKGCATALRAFGARVLVTEIDPINALQASMEGFEVTTMEAACKEARIFVTATGCRDIIRG DHFSQMLEDAIVCNIGHFDIEIDVKWLEDNAAAKDTIKPQVDRFTLKDGRHIILLAEGRL VNLGCAMGHPSFVMSNSFTNQVLAQIELWSKKGTYKIGVHMLPKKLDEEVATAHLEHLGV KMTRLTAAQSEYLGIPLEGPYKPDHYRYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXMSSSNVENFSPQIIRHLAKEMSELQKNPPEGVKVFINDEDITDVQASIEGPAG TPYAGGFFRVKLILSKNFPSEPPKGFFLTKIFHPNVAQNGEICVNTLKRDWKAEFGIKHI LLTIKCLLIVPNPESALNEEAGKLLLEQYDDYSTRAQRFTEIHAKPMFQSMLQTVKNSPF ASPFGLKVNPDRIISAAAESYSCEYGSPKFFAYCAFGGLLSCGVTHTSVVPLDLVKCRMQ VDPGKYGNIINGFRVTLREGGIRELGKGWAPTFFGYSMQGVGKFGFYEIFKMFYSGLMGE ENTYLWRTSLYLVASASAEFFADIFLCPMEAVKVRIQTSPGWAGTLREGVPKLFGEEGMM GFYKGIVPLWGRQIPYTMMKFACFERTVEALYMYVVPKPRAECTKGEQLMVTFVAGYIAG IFCAIVSHPADTIVSKLNKDPGASFMGVAKDLGFAAMWKGLFPRIIMIGTLTALQWFIYD SVKVYYRLPRPPPPTMPESLRLKLE-WRNERIAAIALIPLIPAGILVPMDFILAALVLHC HWRLSGVCEDYIHMSILAFGSLCYLNYSDVGLGNAVRMLYSELXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRRQPHLSKQ DLNKIGIANLTPLTPEVMSRQATINIGTIGHVAHGKSTVVKALSGVQTVRFKNELERNIT IKLGYANAKIYKCDEPNMPKPQCYTSRGSVHPDEFPCDYPNCGKYKLVRHVSFVDCPGHD ILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQ AHDQYEQILKFIQGTIADGAPVIPISAQLKYNIDVVCEYIIKKIPVPVRDFLSEPRLIVI RSFDVNRPGCEVDDLTGGVAGGSVLRGVLKVGHEIEVRPGIVSKDTEGKLTCKPIFSKIV SLFAEQNDLQYGVPGGLIGVGTKIDPTLCRADRLVGQVLGAIGSLPDIFIELEISYFLLR RLLGVRTEGDKKGAKVQKLSKNEILMVNIGSLSSGGRVLAVKADLAKIGLTSPVCTEVRE KIALSRRVEKHWRLIGWGEIRRGVNVKP-AELLLDSDIRVWVFLPIVLITFLVGIIRHYV TILLSSEKKVEIQQIADSQAMIRSRMLRENGRFIPRQSFLMRKEFFNNKETGYFVNNPMT DPSMMMDMMKGNLTNVLPMIVIGGWINWAFSGFLTTKVPFPLTLRFKPMLQRGIELGSLD ASWVSSASWYFLNVFGLRSMYNLILGQDNAADQTRMMQDQMSGAAMAMSPDPSKAFKAEW EELEITDHNWALEEVEEEIMMFLFDWLASVLNVLGLYKKSGKLVFLGLDNAGKTTLLHML KDDRMAQHVPTLHPTSEELTMGGMKFTTFDLGGHAQARRVWKDYFPAVDGVVFLIDSFDR ERFVEAKAELDSLLTDEQISNAPVLILGNKIDIPGAASEDEIRHIFGLHGQTTGKGTVAR SDLRPMELFMCSVLKRQGYGEGFRWLAQYINVIRRNRPGTLASEWSNWPNESFEEMDSTL AVQQFIQQAIRNDFTNIDDILSPPEGQDEGVWKYEHLRQFCMELNGLAVKLQCECNPETC SQMTATEQWIFLCAAHKTPKECPAIDYTRHTLDGAACLLNSNKYFPSRVSIKESSVAKL- ---------------------------------------------------------MPN IKLQSSDGEIFDVDVEIAKQSVTIKTMLEDEEDDEEAVPLPNVNAAILKKVIQWCTYHKD DPPXPEDDENKEKRTDDISSWDAEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMI KGKTPEEIRKTFNIKNDFTPAEEEQVRKENEWCEEK---------------------KKD WYDVKAPCMFNKRQIGKTLVTRTIGTKIASDGLKGRVFEVSLADLQDDEVTFRKFRLIAE EVQGRHVLTNFH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------KNEVFLDVIESVNLLVSANGNV LRSEIVGAVKMRVYLSGMPELRLGLNDKVLFESTGRGKSKSVELEDVKFHQCVRLSRFEN DRTISFIPPDGEFELMSYRLNTHVKPLIWVESVIEKHMHSRVEYMIKAKSQFKRRSTANN VEIIIPVPMDADT----------------------------------------------- ----PPVALTFEVSGCVCSGLQIRFLRVCQQDAYIPQRWIRYITTADSY----------- ------------------------------------------------------------ ------------------------------------------------------------ -----EVIAVARTADVVIMMLDALKGDKQRELLEMELEAVGIRLNKRRPNIYFKIKKGGG LSFNSTLPLTHCNEKLVQMILHEYKIFNAEVLFRENCTADEFIDVIMGNRVYMNCLYVYN KIDQISIEEVDRIAHTPHSVVVSCNMRLNLDYLLEQLWESLALVRVYTKKRGEHPDFEGG LILRRG-CSVEXVCHVIHRQLKSQFKYALVWGKSAKYSPQRVGIQHSMCHEDVIQVVKK- ------VIFCHHIFVSAIGRLCEKCDGKCLICDSYVRPCTLVRICDECNYGSYQGRCVIC GGPGVSDAYYCKECTIMEKDRDGCPKIVNLGSAKTDLFYERKKYGFKKRPNLPPISGEKL TGKSDTRKVWVPANRYTPLKDNWMKIFTPIVEHLHLQIRFNVKTRNVEIKTCKETTDIGA LQKAADFV---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------PIICKTIPRL VPGWTQSIVVGRHAFGDQYKATDFVVPGPGKLEMIFTPSNGEAQKMEVYTFKDGGGVGMG MYNTDESITGFAHACFQYAIKKKWPLYMSTKNTILKRYDGRFKDIFEDIYEGNYKGEFEK LGIWYEHRLIDDMVAQVLKSNGGFVWGTKNYDGDVQSDIIAQGYGSLGLMTSVLMCPDGK TIEAEAAHGTVTRHYREHQKGNPTSTNPIASIFAWTRGLEHRGNLDGNKDLVRYAQVMEE ACIETVDAGKITKDLAGCIYGIKNVKPDQYLNTEDFLDAINETF-MGKLLSKIFGNKEMR ILMLGLDAAGKTTVLYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWR HYYAGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMKPHEI QEKLGLTRIRDRNWYVQPACATAGDGLYEGLTWLTSNAKSFGDLKSEAGISALNGYLSDK SYIEGYQPSQADAVVFGALSGPSEKFPNALRWYKHISSYGSDCKSFPGATKSLDSYGGST -KADDDDDDIDLFGSEAEKLKEERIAAYTARKAVAVVAKSNIVLDVKPWDDETDMKEMER CVRTVACDGLLWGASKLVPLAYGIK----------------------------------- -------------TGLERIGAHPHPRS-GIDGCLEARQXSKA-CGTSSGQRAAGIILEVS QRGEDSWSSHLIAGQPGTGKTAIAMGMAQALGSDTPFTSIAGSEIFSLEMGKTEALTQAF RKSIGVRIKEETEIIEGEVVEIQIDRPASGTGAKVGKLTLKTTEMETIYDLGQKMIESLT KEKVQAGDVVTIDKATGKITKLGRSFTRARDYDAMAAQTKFVQCPEGELQKRKEVVHTVS LHEIDVINSRTQGFLALFSGDTGEIKT-VREQINQKVAEWREEGKAAIVPGVLFIDEVHM LDIECFSFLNRALETDMAPILIIATNRGITRIRGTNYQSPHGIPIDLLDRLLIISTSPYE EKEI-QILQIRCEEEDVEMTEDALMVLTRIGMETSLRYAIQLITTASLVCHKRKGTETSV EDIKRVYSLFLDESRSTQFLKEYQQEFMFHE----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------KELVNII QQESYTYRDPITEFLECLYVNFDFDGAXQKLRDCEKVLVNDFFLVACIDDFIENARLLIF ETFIRIHQCISISMLAEKLNMPPEDAERWIVDLIRHSPLDAKIDSKLGHVVMGTNAKSPY QQVIEKTKDLAYKSQMLVMAVEKKLRQK------------DGVTFPTKGQTVTVHYTGTL QNGKKFDSSRDKGRPFNFKVGVGQVIKGWDEGVIQMSVGQRANLTCSPDYAYGPQGIEGV IPPNATLLFDVELLGVKMPKYYCDYCDTYLTHDSPSVRKTHCNGRKHKENVRVYYQKWLE EQVQQLVDDTTAAFKAGASKSS----GGAAIPPPSNM-GPMPGP-MGMMGPGPGGPMPPM RPPMGPMGHMGPMGAPPETLSLERDVQRAIALLDQLQRSGNFEKLAALQQVLQSDFCAAV REVYEHVYETVDITGSPEVRASATAKATVAAFAASEGHAHPRVVELPKTEEGLGFNVMGG KEQNSPIYISRIIPGGVADRLGGLKRGDQLLSVNGVNVDGEPHEKAVDLLKAAQGTVKLV VRYTPKVLEEMEARFDRQRNARRRQLVCLLGAAFADPTIYFKEEFWDSRWVESTHKGSEQ GSFKHTAGKFFNDKEKDKGIQTSQDARFYGISAKFDKPFTNEDKTLVIQFSVKHEQNIDC GGGYVKLFGSDLNQKDMHGDSPYLIMFGPDICGPGTKKVHVIFNYKGKNLLTTKDIRCKD DVFTHVYTLIVRPDNTYEVKIDNKKVESGALESDWEFLLPKKIKDPDAKKPEDWDDREKI DDPDDKKPEDYDKPEHIVDPDAKKPEDWDDEMDGEWEPPMIDNPDYKGEWKPKQIDNPAY KGVWVHPEIDNPDYKADDSLYKYTDIGAIGFDLWQVKSGSIFDNVLITDDEKYAEEFAEE TWGKTKEGEEKMKNEQDEEEKKKREEEDKKTKEESDDADEEEEEMDTSVPEPSLYIVKAI LILDNDGNRLISKYYDDTYPTPKEQKSLFTKTHRANAEIIMLEGLTCVYRSNVDLFFYVI GSAQENELILVNVLNCFYDAVSQILRKNVEKRA--------------------------- -------------------------------------MNIFRLSGDLSHLLAIILLLIKI WKTRSCAGVSGKSQIMFAMVFTTRYLDLLTNFISLYNTTMKVVFISCSIATVYLMFVKFK ATYDSNHDTFRMEFLVVPVAGLAFLVNHDFSPLEILWTFSIYLEAVAILPQLFMISKTGE AETITSHYLFALGVYRALYILNWIYRYYFEGFFDLIAVVAGCVQTVLYCDFFYLYITKVW KGKKLTLPAMKIEEVKSTTKTLRIATHSHVKGLGLDESGYAHQSSAGLVGQELAREAAGI VTDMIKSKKMAGRAVLLAGPPGTGKTAIALAIAQELGSKVPFCPMVGSEVYSTEIKKTEV LMENFRRAIGLRIKETKEVYEGKXDRADSAETENPMGAYGKTVSHVVIGLKTAKGTKQLK LXPSIYESLQKEKVEVGDVIYIEANSGAVKRQGRSDAFATEFDLEAEEYVPLPKGDVHKK KEVIQDVTLHDLDIANAKPQGGQDIMAMMGQLMKPRKTEITDKLRKEINKVVNKYIDQGI AELVPGVLFIDEVHMLDIECFTYLHRALESSLAPIVIXATNRGKCTIKGTEDVISPHGIP LDLLDRLMIIRTLPYSQEEMSQIIKIRAQIERIDISDESLQALSEVGVKTTLRYAIQLLT PGSLLANINGKQLIGREEVEEINELFFDAKSSAKVLSEQEDKYMKDFQVDDEGDQGLQKL KEKAKKRKGRGF-TRTDVDEYEGMEVKGPGPQRSVEGWILFITNVQEEAQEDDVIDKFAD YGEIKNLHMNLDRRTGYLKGYALVEYETFGEAQKAIENLNGSEILGQKINVDWCFVRGPS KK-MSYQLYRNTTIGHTLQESLDELIQCGQITPQLALKVLLQFDKAINNALSTRVKNRIS FKGHLNTYRFCDNVWTFVLNDVEFKNVTKVKIVACDGKG-FLFTSESVGEGHPDKICDQI SDAILDAHLKQDPNSKVACETASKTGMIMLLGEISSKAVVDYQKVVRDTIKYIGYDDSSK GFDYKTCNVLSALEEQSPDIAQGVHEGRNEDDIGAGDQGLMFGYATDETEECMPLTVVLA HKLNAKIAELRRSGGLPWARPDSKTQVTCEYRMQKGVCIPQRVHTVVISIQHSDDVTLEK LRKDLMDKVVAKVIPAKYLDERTVFHMQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAH GGGAFSGKDFSKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVAEPLSIFVSSYGT GVKSDDELLKIVKNNFDLRPGRIVRDLDLKRPIYQKTACYGHFGRPDFSWEEPKKLVFMA GSALKRLMAEYKQLTLNPPEGIVAGPVDEENFFEWEALITGPEETCFEGGVFAAKLTFPS DYPLSPPKMKFTCDIFHPNIYSDGRVCISILHAPGDDPMGYESSAERWSPVQSVEKILLS VVSMLAEPNDESAANVDAAKTWRDNRARFNEIAHQTVRKSLGL----------------- ---FVRNDCKVFRFCRSKCHRAFKKKRNPRTVRWTKAFRKAAGKELTVDPSFEFEKRRHV PVKYSRELWQDTVKAMKKIDMIRVRRQNQFITNRLKKGKELRKEADIKEVEKNIHLIKSP AVGMAAYKVVMIRHGESEYNQANRFCGWHDADLSETGIQEAKNGGQIMKEKGYCFDVAFT SVLKRAIKTLYYVQDALDLHWIPVHRHWRLNERMYGALQGLNKSETAAKHGEEQVKIWRR SYDVPPPAVETTDERWPGSDPKYEMMDKNLVPRAECLKDTVERVLPYWYDVIVPEIKRGQ RVLIAAHGNSLRAMVKYLDNMTDEAIMGLNIPTGIPLVYELDKDLRPVMHYYLASEAEIK AAMDKVAAQGKA-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--LLFGSRSNKTFKPK KNIPEGTHQYDLMKHAAATLGSGNLRLAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTVT EFCTEQSCPVMSAGPRYEYHWADGHTIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKI GVPFPRNFLSMAKTILKRLFRVYAHIYHQHFPQVIQLEEEAHLNTSFKHFIFFVQEFGLV DKRELAPLQELIDKLTSKD----------------------------VKLYRFLARRTNA KFNKIILKRLFMSKIHRPPLSLARLIRLMAKPGRPDKMAVCVGTVTDDMRIFKVPKLKLC ALRVTEGARXRILKAGGEIITFDQLALRAPKGQNTVLLQG-------------------- ---------------------------DVKQGTIVGSFNVAKTVGLMRRLIAQSKWHTAE DLMKLVKEEGKRLIEAEPSETAIGNMVRRVLKIVREEYTIEAVNELILELETSAQALEHI HAKEVVKTVEAFLKRKFHV----------------------------------------- ------------------------------------------------------------ -------------------------------------MIIPVRCFTCGKVIGNKWEAYLG LLQAEYTEGDALDALGLKRYCCRRMLLSHVDLIEKLLNYAPLEKRTPDAVEGRKHIDVQT ELYLEELSDRVEETDATCQTDSFLDRPPSPLFIPAKTGIDVETQIYEGELFHFDIEVKPI LEVLVGKTVEQSLLEVMEEEELANLRMQQRQFEELRNAELVEQQRLEEQERRHREEKERR MMQQKEVLRKEHETTEKIAARAFAQSYLADLVPTVFGTLSDNGYFYDPVERDVEQGFLPW LMGEVEERLQEAVISRMLLDDLIRFVVTRRNKEFMQMKARGELKEYKVIGRLLPTHELRV PPLHR------------------------------------------------------- ------------------------------------------------------------ --------------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSGSASLSAYRDQHFKGNRHEQ ERLLLGSSTLYVGNMSYYTTEEQIYELFSRCGDIKRIVMGLDKFKKTPCGFCFVEYYTRE DGEAAMRFVNGTRLDDRVVRTDW--------QYGRGKTGGQXRDEYRTDYDSGRGGYGKL VKQKLKPAYSLKFTLAGHTKAVSSVKFSQNGEWLASSSADXLIK-SGCFQGKFEKTISGH KLGISDVAWSTDSRLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVS GSFDESVRTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG KWIVSGSEDNMVYIWNLQTKEVVQKLAGHTDVVLCCACHPTENIIASAALENDKTIKLWR SDV--------------------LFYKAQGKSDALIGGNASSGVDVVMNDKKSYMTHIKE YMKRVKEYQFFCGLVLMKW-----------------MAVEFDGGVVIAADSRTSAGTYIP NRVTDKLTKVTDNIYCCRSGSSADTQAIADIVNYHINFHRMEMGEDPLVKTAAKVFQDLC YNYRDSLSAGIICAGWDRKLGGQVYSIPLGGMCIRQPVTIGGSGSTYLYGHVDATFKENM TKEECLKFCKDAVSLAIMRDGSSGGVIRMAAISEDGVEKHLILHEDITKFVMIAIASGLV LLCCCFCICKRCLKKRKKKDGKKGLKGAVDLKSVQLLGSSYKEKVQPDLDELEVNMEDNE DAESAKSEVKLGKLQFSMDYDFQKGELTVGVIQAADLPGMDMSGTSDPYVKVYLLPDKKK KHETKVHRKTLNPVFNESFVFKVQFADIGAKTLTFAIYDFDRFSKHDQIGLVKVPLNSVD LGNVLEEWRDLTSPESESEKET-LGDICFSLRYVPTAGKLTVVILEAKNLKXMDVGGLSD PYVKIAVYQGNKRLKKKKTTIKKRTLNPYYNESFTFEIPFEQIQKVTLILTVVDYDRIGT SEPIGRIVLGCNAAGTELRHWSDMLANPRRPIAQWHTLQEMPEKNMVLADLGRKITTALR SLSTATVINEEVLNAMLKEICAALLEADVNIKLVKKLRENVRAVIDFEEMAAGLNKRRMI QSAVFKQLVKLVDPGVKAWQPTR-EMQRDHVCGSAGSGKTTTCTKLAYYYQKKNWKSCLV CADTFRAGAFDQVKQNATKARIPFYGVDTSGRHKQEESLFEEMLQVSNATPDNVVFVMDA TIGQACESQARAFGEKVDVASVIITKLDGHAKGGGALSAVTGSPIIFIGTGEHIDDFEPF KVQPFISKLLGMGDIEGLIDKVNELKLED-KIDEELRH---------------GQ----- ---------MSIMAYNGAAIVAMKGKECVAIASDRRFGIQAQTVGMDFQKIFEMGPHLYI GLPGLATDVQTVAQRLKFRLNLYELKENRQIRPKTLMSVVANLLYERRFGPYFVEPVIAG LDNKTAEPYIAALDLIGCPMATDDFVVSGTCTEQLYGMCESLWQPDMDADALFECISQSL MNAVDRDAVSGWGAVVTLIEKDKVTTRTLKARMDMTSKDYYFDSYAHFGIHEEMLKDEVR TLTYRNAMYHNKHLFRGKVVLDVGCGTGILSMFAAKAGAKLVIGIECSSIVDYAEKIVKD NKMDDVVKLVKGKVEEVTLPEGVEKVDIIISEWMGYCLFYESMLQTVIYARDKWLAHDGL IFPDRATLYVCAIEDRQYKDEKINWWDNVYGFDMSCIRKVAISEPLVDVVDPKQVVSNSC LVKEVDIYTVKETDLTFSAPFHLQCRRNDYVQALVTFFNIEFTKCHKRTGFSTGPDAQYT HWKQTDEYITAKKGEELFGVLTMKPNKRNTRDLDFSIDIDFRGELCEMVQTMNYKMR--- ---NSWKANYFLKIIELLDEYPK------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------ALTAGKLLAIIGDEDTCTGFLLGGVGELDKHRRPNFLVVD ATTTVSEIEDAFTNFSKRDDIAIILINQNVAEMIRHILDNYTAPIPAVLEIPSKNHPYDA NKDSILRRAKGMFSADEL-GNESSLPMELCSTFDPDEIKRLGKRFKKLDLDNSGALSVDE FMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKESKLRFAFKIYDMD KDGYISNGELFQVLKMMVGNNLKDAQLQQIVDKTIILADLDGDGKISFEEFCAVVGTLDV HKKMVVDVMTYINSWEEFAKAAEKLYLADPAKCRFVMKYRHCGGQLVIKMTDDRVCLQYQ TEHAQDIKKLEKLTSQLMRHMASK-LYEEVKLFKGSREREKYDNLAELYAIINTLQYLEK AYIKDSVKPKEYTANCSKLLVQYKAAFKQIQGREYPTLESFVXKSKLNCPAAMERIKEGR PITIRDDTGNTSRCIADIVSLFITVMDKLRLEIKAMDEIYPDLRELMDTMNRLSMLTDDY EGKKKVQTWLTTLEAMQASDELSESQVRQLIFDLESSYGAFTSLLH-MLSSMVKEHQLKQ QARKEVQERKKKAATAATALTHSLVDYLNSGVAQAYVNQKKLDTETKILQANATHFAKQT AQWLKLVEDFNQSLKEIGDVENWARSIERDMHTISNALEYAYK----------------- ------------------------------------------------------------ ---------------------------------------------EYFKRQKLNKPKHTE GEIFDTEKAEYAVSAERREDQIAVDKQVLDVIKKHQDKKFMFGYLGSLFSLTNKQYPHKM VFMEWLFGKKKTPQQLLRQNQRALTKAMRELDRERQRMEQQEKKVIADIKKMAKAGQMDA VKIMAKDLVRTRHYVKKFIVMRANIQAVSLKIQTLKSNDSMAQAMKGVTRAMAQMNKQMK LPEIQKIMMEFEKQSEIMEMKEEMMNDAIDDAMGDDDDVEETDAIVAQVMDELGLQLTDQ LSGLPETGKSGGKQAVPVDDADADLEARLDNLRRQNNYCDFCLGLETDNKKTGEKEPLFS CADCGHSGHPSCLQFTPNMIISVQKY---------------------------------- ----------------------------DRGISLYPLTNYTFGTKEALFEKDSSVTSRFN RMREEFDKNGMRRSVEGVLIVHEHGLPHVLLLQLGTTFFKLPGGELNANEDQVDGLKRLL SEMLGRSDQVPVNWVIENVIGNWWRPNFEPPQYPYIPAHITKPKEHKRLYLVQLPEKALF AVPRNYKLVAAPLFELYDNSAGYGPIISSLPQALSRFSFIYNFTPSGTTPTGSKAMAMAT PTPGHVMSMTPEQMQAWTWQREIDERNRPLSDEELDAMFPSGYKVLQPPAGYVPIRTPAR KLIATPTPMAGTPVGFRMQTQIVDMQPKGNLPMMKPDDMQYFDRKIMKLLLKIKNGTPPM RKAALRQITDKAREFGAGPLFNQILPLLMSPTLEDQERHLLVKVIDRILYKLDDLVRPYV HKILVVIEPLLIDEDYYARVEGREIISNLAKAAGLATMISTMRPDIDNMDEYVRNTTARA FAVVASALGIPSLLPFLKAVCRSKKSWQARHTGIKIVQQIAILMGCAILPHLKSLVEIIE HGLVDEQQKVRTITALALAALAESATPYGIESFDSVLKPLWIGIRTHRGKGLAAFLKAIG YLIPLMDAEYANYYTREVMLILIREFQSPDEEMKKIVLKVVKQCCATDGVEPQYIKDEIL PAFFKHFWNQRMALDRRNYRQLVDTTVEIANKVGAAEIVSRVVDDLKDEAEQYRKMVMET IDKIMSNLGAADIDSRLEEQLIDGILYAFQEQTTEDVVMLNGFGTVINALAKRVKPYLPQ ICGTILWRLNNKSAKVRQQAADLISRIAIVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLG SILGALKGIVNVIGMTKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGAEFVS AREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVC TTVAIAIVAETCSPFTVLPGLMNEYRVPELNVQNGVLKSLSFMFEYIGEMGKDYIYAVAP LFEDALMDRDLVHRQTSMAAIQHIALGVYGFGCEDALTHLLNYVWPNIFETSPHVVQAFM GSIEGMRVGLGATKVLQYGMQGLFHPARKVRDVYWKVYNTIYIGAQDSMIPAYPRVPNDD KNQFVRYELDYILDDFMCDDEEYNLEYSEDSNSEPDVDLENQYYNSKALKEDDPRLALDS FQKVLELEGKDKGEWGFKALKQMIKINFKLGRVNEMMDRYKQLLSYIKSAVTRNYSEKSI NAILDYISTSKQMELLQNFYETTLDALQEAKNDRLWFKTNTKLGKLHFDRGEYRK-QKIL KQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPL IMGVIRECGGKMHLREGEYEKAHTDFFEAFKNYDESGSPRRTTVFEYLVLANMLMKSGIN PXDSQEAKPYKIDPELLAMTNLVSAYQNNDINEFEKILKINSVNIMXIYSIREHI----- -----------------------------------------------------NQVLELD TGFARYSAMDKWTAQLSALHLSIVNKMAVLLMGKSGSGKTSMRSIIFANYIARDTRRLGA TIDVEYCHVQFLSKLVLNLWDCGGQEAFMENYFASQRDNIFRNVEVLIYVFDVESRELEK DMHYYQSCLEAILQNSPDAQVFCLIHKMDLVQEDQRELIFKEREEDLKRLSKPLATSIWD ETLYKAWSSIVYLLIPNVKKIEKSLNTFANIIDADEVLLFEKASFLVISHCERKAHIDMH RFEKISNIIKQFKLSCSKLAASVQSMEVHNSCFAAFVDIFTPNTYVMVIMSDPTIPSAAT LINIRNARKHFVELEKQE-ILSFSTRLFSVLRFESVIHEFDPYFNYRTTRFLVEEGFYNF HNWFDDRAWYPLGRIIGGTIYPGLMITSAIFYHLMHFIHFTIDIRNVCVFLAPLFSSLTA LVTYVLTKELKDAAAGLVAAAMISIVPGYISRSVAGSYDNEGIAIFCMLLTYAWWIKSVK TGSLFWAIMCSLAYFYMVSSWGGYVFLINLIPLHVLVLMATGRFSHRVYVAYSTVYCLGT LLSMQISFVGFMPIQTSEHMAALGVFGLCQIHAFIDYVRSKLTREQFSLLFRAVILVASI AIAMASGKIAPWTGRFYSLLDPSYAKNNIPIIASVSEHQPTTWSSFYFDLQMLVFMFPAG LYFCFKKLTDANIFIILYGVTSIYFAGVMVRLMLVLAPVMCILSAIAVSSTLNTHMKNLD VAKKTDINYPFKNEVATTVVVLVTLFLVTYTFHCTWVTSEAYSSPSIVLSARGGDGSRII FDDFREAYYWLRQNTPEDAKVMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMSS TEDKAYEIMRELDVNYVLVIFGGLTGYSSDDINKFLWMVRIGGSTDRGAHIKETDYFTPQ GEFRIDKDGSSTMLNCLMYKMCYYRFGSVYTEQGKPTGYDRVRNAEIGNKDFELDVLEEA YTTEHWLVRIYKVKDLDNRG-HLNMRPLLRLICQRFFGEFTGFTSMCVQFIKSPLANAKA KVEHIYTGPLDTELAEAMFECDPDGPLMVHTTKLYPTEDATSFHVFGRVISGTLHANQEI RILGENFSLQDEEDSR-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------ARSIWAFGPDSTGPNILVD DTLPSEVDKSLLSSVKDSIVQGFQWGTREGPLCDEPIRNVKFKILDAVIAQQPIHRGGGQ VIPTARRVAYSAFLMATPRLMEPYFFVEVQAPADCVSAVYTVLARRRGHVTQDAPVPGSP LYTIKAFIPAIDSFGFETDLRTHTQGQAFCMSVFHHWQIVPGDPLDKSIHIRPLEPQPAT HL-------------------------------------------QETFSLFDNKGDGKI YAHQLGDVLRAMGQNPTESEVRKCSDPDFRISFETFLPILSTISKNRDTSTIEDFIEGFR VFDKEQNGMINSAELRHLLSSLGEKMTDEEVNELLMGQEDAQGNVNYEEFVKMVLNGMAE YGFNIDNGYLEGLVRGFKGGILRQADYLNLVQCDTLEDLKLHLQSTDYGTFLSNEASPLT VSVIDDKLREKLVIEFQHLRTHAVEPLATFLDYVTYSYMIDNIVLLITGTLHQRSISELI PKCHPLGSFEQMEAIHIAATPAELYSAVLVDTPLANYFIDCISEQDLDEMNIEIIRNTLY KAYLEDFYKFCEEMGSETAEVMCEILAFEADRRAFIITINSFGTELSKDDRAKLYPRCGK LHPDGLGALARADDYDQVRAVAEYYGEYRTLFDDVSSTAGEKTLEDKFFEHEVKLMKNAF MQQFHFGVFYAFIKLKEQECRNIIWIAECVAQRHRAKIDSYIPIFSPRKAVRKISKIPFK VLDAPELQDDFYLNLIDWSSQNVLSVGLGSCVYLWSACTSQVTRLCDLSCDNDTVTSVSW SERGGLVAVGTDKGFVQIWDVAMNKRITTLDGHSARVGALAWNADVLSSGSRDRLILQKD IRTPSLVPERKLTGHRQEVCGLKWSPDHQHLASGGNDNKLFVWNVTSSSPVQTYTEHLAA VKAIAWSPHQHGLLASGGGTADQCIRFWNTLTGQPLQCVDTGSQVCNLAWSKHSNELVST HGYSQNQILVWKYPSLLQIAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTR STKESKSVLNMFTRIRLLIIIGLYYNLTNQGYRFNFEWFLVGISPYQWANTGIGLAISLS VVGAAWGIFTTGSSILGAGVKVPRIRTKNLVSVIFCEAVAIYGIIMAIVIGNVMNYMAGY AMFAAGLTVGFTNLSCGLCVGVVGSGAALSDAANPSLFVKILIIEIFGSAIGLFGVIVAI LQTTNLKMGDKMAASRRLAKELQDQVDESNILLWTGLIVPENPPYSKGAFRIKIEFPAEY PFKPPKITFLTKVYHPNIDEKGQVCLPIISAENWKPATKTDQVIQSLVALVNDPEPEHPL RADLSEEYSKDRKKFMKNAEEFTKKYSEKRPTDGAAETFPMQCSALRKNGYVVLKDRPCK IVDMSTSKTGKHGHAKVHLVGLDIFTGKKYEDICPSTHNMQVPHVKRTEYQVIDFTTNFF CLMDDAGETRDDLKFTATVWKAMGTEMVKELRAAKGKLLGPKGVCVNNSGHIIVVDNKAS CVFVFQPNGKLLHKFGSRGQHQFAGPHFCAVNADEDIIVSDFHNHCIKVFNEGTFLFSFG SNGEGNGQFNAPTGVTVDKHGNILVADWGNSRIQVFDGQGSFVSYISLYGPQGLAVTSDG HVVVADSGNHCFKIYKYLMAAGPIAERNQDATIYVGGLDEKVSEAILWELFLQAGPVVNV HMPKDRITQAHQGYGFIEFMGEDDADYAIKIMNMIKLYGKPIRVNKASAHQKNLDVGANI FIGNLDPEVDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFEAADMAIEAM N----------ISYAFKKDSKGERHGSAAERLLAVQNPLSQADRPHQLFADAPPSQQNIP LVPPPPPPVSGDTGAPPPGMPG---IPPPFMPPFM-PPPGMMPPGPPPFGPQMPPGMRGP PPPPPPRGMRPPPGMRPPPM---------------------------------------- ------------------------------------------------------------ ----------------QSGINTVTTLVEQKKAQLVVIAHDVDPXXXLXFXPPSCETKVVH YCI--------------------------------------------------------- -------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSIKAIHAR QIFDSRGNPTVEVDLTTANGMFRAAVPSGASTGIYEALELRDNIKAEYHGKGVLKAVSNV NKLIAPALVLDVADQKAIDKIMLDLDGTENKSKLGANAILGVSLAVCKAGAAKKGVPLYQ HIADLAGNKGVIMPVPAFNVINGGSHAGNKLAMQEFMLLPTGATSFTEAMRMGSEVYHHL KSVIKGKYGQDACNVGDEGGFAPNIQNNEEGLDLLKTAIEKAGYTGKIKIGMDVAASEFC KKYDLDFKNPNSKPADYLSSDQLLKIYEGFVSKYPVVSIEDAFDQDDWDAWTKMCGIQLV GDDLTVTNPKKVKEAIDRKACNALLLKVNQIGSVSESIQACKMAQAAGWGVMVSHRSGET EDNFIADLVVGLCTGQIKTGAPCRSERLSKYNQLLRIEEELGSKAKYAGENFRHPGGPPK AGAFQRRPSGFTSFRKFYERGDFPIALEHDTKGNKIAWKVEIEKLDYHHYLPLFFDGLCE TEHPYEFFARQGVHDMLEHGGSKILPVIPQLIIPIKNALSTRNAMVMCITLKVLQHLVVS AEMVGEALVPYYRQILPVLNIFKNKNLNSGDGIDYSQQKRENLGDLIQETLEAFERHGGD DAFINIKYMVPTYESCMMNAPQTFESFLLFEGEKKXTYEKDTKVPNAVVFTVNKEDHTLG NMLTTQLLKDPQVLFAGYKIPHPLENKFVLRVQTTPEYSPQEAFTNAITDCISEISLLEE RFRESIKEKQEGD-------------------------KKEAPIKRDLLRPRDYRVDLES KLGKSQVITKTTPSSHQGGYFCNVCDCVVKDSINFLDHINGKXHQRNLGMSMKVERSSLE QVKKRFEMNKKK------------------------------------------------ --------------MGCTMSQEERLAMERSKQIEKNLKEDGMQAAKDIKLLLLGAGESGK STIVKQMKIIHEGGFTSEDNKQYKPVVYSNTIQSLVAIIRAMGTLNIAFGEPERESDAKM VLDVIARMEDTEPFSEELLHAMKRLWSDTGVQECFSRSNEYQLNDSAKYFLDELDRLGAK DYMPTEQDILRTRVKTTGIVEVHFHFKNLNFKLFDVGGQRSERKKWIHCFEDIV------ --------------------------------------EEKIKKSSLTVCFPEYTGKQTY DDAAAYIQAQFEAKNKSTSKEIYCHQTCATDTNNIQFVFDAVTDVIIANNLRGCGLYYHS QFPKPPQLAGNIAVLPLRTHFKGPA-DIIDEALMFFKANVFFKNYEVRNEADRTLIYITL YITECLKKLQRCQSKNQGLKEMNSLAL------GEAQFPLNSMYARPANRMDEDLMRSYL QQIRHETGVRVAEKVFDPATDKPSKWWMCFVKRKFMDKSLSAPGQTGPYNYSYIFKYIII GDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVAGQKIKLQIWDTAGQERFRAVT RSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIFLIGNKSDLEAQRDVTYE EAK------------------------------------QDGSLDLNAAESGVQHKPTSP RNALNTDQAQNKEGCGC-------------ISGTVMFSQPDDVTITVKLSGFATRKHGFH VHEKGDLGDACKAAGGHYNPHHKPHGAPVDVERHVGDLGNVEQDDTVIKDKVVSLAGEYS VIGKSIVIHEGEDDLGKGTYSDSKTTGHAGARLGCCVI----MVNFTVDEIREIMDKKKN IRNMSVIAHVDHGKSTLTDSLVSKAGIIAGARAGETRFTDTRKDEQERCITIKSTAISLY YTLPEKDLLSSFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQA IAERIKPVLFMNKMDLALLTLQLEAEDLYQTFLRTVENVNVIIGTYADDEGPMGEIMVDP TKGTVGFGSGLHGWAFTLKQFAEIYADKFKIEESKLMRRLWGDQFYHFVRGFTQYILDPI YKVFEFCMPKEDTLKLVEKLGIKLTVDDKEMHEKQLLKVVMRKWLPAGDALLQMITIHLP SPVTAQNYRIELLYEGPMDDEVGVSMKACNPKGPLMMYISKMVPTSDKGRFFAFGRVFSG ICSTGLKVRIMGPNYTPVKNIQRTILMMGRYMEPIEDVPCGNICGLVGVDQFLVKTGTIS TYDLAHNLKVMKFSVSPVVRVAVECKNAADLPKLVEGLKRLAKSDPMVQCSIEESGEHII AGAGELHLEICLKDLEEDHACIPIKVSEPVVSYRETVSAESSQMCLSKSPNKHNRLFMRA VPMPDGLPEDIDSGDVSARQEMKERARYLADKYNYDITEARKIWCFGPDGTGPNMVCDCT KGVQYLNEIKDSVVAGFQWATKEGILCEENMRGVRFNIHDVTLHADAIHRGGGQIIPTAR RCLYASVLTAQPRLLEPVYLVEIQCPENAVGGVYGVLNRKRGHVFEECQVTGTPMFLVKA YLPVNESFGFTADLRSNTGGQAFPQCVFDHWQELIVAVTRKRKGLSENVPSLDKFLDKMM LPLSLLRTAVNHPMLVELKNGETYNGHLVSCDNWMNINLREVICTSRDGDRFWKMPECYI RGSTIKYLRIPDEVIDMVKEEVIVKGRGRGE--LRGRGGPGRGAFGNRGGRGGRGGRGGP RGGNEFKLNNPPTDGVSAVKFSPVSPQFLLVSSWDCSVRLYDTNNNSMRIKYTHSAPVLD CCFYDTVHSYSGGLDKALKTYDFNTSTETIVGHHEQPIRCVEYCPDVNVIVTGSWDSXVK LWDPRAPCSAGSFSQPDKVYTLSLCGDKLVVGTAGRRVLVWDLRNMGYVQQR-------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------MDFQHRAGGKTGTGGVASASDANRDRRERLRQLALETIDI NKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQANLARRAAKEAKDAPAQPAPE KAHVDIKKFVKIGRPGYKVTKQRDPESGQQSLLFQIDYPEIVDGVIPRHRFMAAYEQKVE XPDRKWQYLLFAAEPYETIGFKVPSREVDK------------------------------ ------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------TVPAYFNDGQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKKEGEKNI LVFDLGGGTFDVSLLTIDSGVFEVVSTNGDTHLGGEDFDQRVIDYFIKVYKKKKGKDIRS SNRAVQKLRREVEKAKRTLSSQHQARIEIESLFEGEDFSEMITRAKFEELNMDLFRSTMK PVQKVLEDGDMKKTDIDEIVLVGGSTRIPKVQQLVKEFFSGKEPSRGINPDEAVAYGAAV QAGVLSGEEDTGEIVLLDVNPLTMGIETVGGVMTKVIGRNTVIPTKKSQIFSTAADNQPT VTIQVFEGERPMVKDNHLLGKFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGN KNNIVINNDQNRLSPEDIERMINDAEKFADDDKKVKERVEARNELESTAYSLKTQINDKE KLGAKLSSDEKTTIEKAVTEQIEWLEKNPDADVDELKEHKKALDEIVQPIISKLYQGAPP P---------NAGVEDPELEAIKARVLEMEQEAEKLKEMQSEVEKQMTPEERLEADGRSI YIGNVDYGATAQELEAHFHGCGSVNRVTILCDHFTGHPKGFAYIEFADKESVQTSLALDD SLFRGRQIKVSAKRTNRPGISSTDRPPRGRGFRGRGRGFYYGYTPRGRGRG-YRSRRASY YSPYVLYGTLVELAQSATFHTLTDAVGNEKGKKAALQEMILKEEEGRRRVKALQKQLVDV RREKEVELQHRNEMIAHLKDQLQEMKAKTSMEGKYIKKVAEVSVAQSQKKCVLTEKQMRD GIKDLKTKIDEETRVNTEVESFLLGHTQRLQKQVEHWMEKYDKDVEAKQKELDILKASKA KDLERLQYLSKLYSDYEQVVVEDRIEKEKARRKAELEAEQLKCAVKVQAWWRGMMVRKCL GAFSKKKKGKPKVGINGFGRIGRLVLRAALKAVSVVAVNDPFIDLQYMVYMFKYDSTHGR FEGSVILVIEGKSIEVFMERDPAKIPWGKSGAEYVVDSTGVFTKIDGAKAHIQGGAKKVI ISAPSPDAPMFVMGVNQDKYEKTMNIVSNASCTTNCLAPLAKVINDKFGIIEGLMTTIHA YTATQKTVDGPSAKAWRDGRTAGQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPVPDV SVVDLTCRLNKGATFDEIKAAVKGPMKGILAYTEEQLVSTDFLTTTVSSTFDAGASIVLN ANFVKLVAWYDNEFGYSCRIVDLVKYMYGRDREDLATAILRSKSRPNRLCVEEAINEDNS VVSLSQGKMDELQLFRGDTVLIKGKRRRETVCIVLSDDTVGDEKIRINRCVRNNLRVRLG DIVSIQACPDVKYGKRVHVLPIDDTVEGLTGNLFEVYLKPYFLEAYRPIHKGDIFLVRGG MRAVEFKVVETDPSPYCIVAPDTVIHCEGEPVKREEEEEALNEIGYDDIGGCRKQLAQIK EMVELPLRHPQLFKAIGVKPPRGIMLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSK LAGESESNLRKAFEEAEKNAPAIIFI---------------------------------- ---------------------------------IPDPTGRLEILRIHTKNMKLADDVDLE QVAAESHGHVGADLAALCSEAALQQIREKMDLIDLEDDSIDAAVLDSLAVSQANFRWAMS KSNPSALRETSVEVPNVSWNDIGGLESVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFY GPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFD ELDSIAKARGGNIGDGGGAA---------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------SGTSSFGTSNIFSSA-NVNPMKDIEVTSPPDDSVSCMAFSPGVLPSTFIVVG SWDNNVRCWEVQQDGQTIPKAQQTHTGPVMDVAWSDDGTKVFTASCDKSAKMWDLGSNQF VQVAQHDAPIKTCHWVKAPNYNCLMTGSWDKTLKFWDLRSSNPMLVINLPERCYCADVVY PMAVVGTAGRQVIIYTLETEPREFKRIESPXKFQHRCVSIFPDKKTSAPTGFALGSIEGR VAIHYVNPQNPKDNFTFKCHRGGVQDIYAVNGIAFHPVHGTLATVGSDGRFSFWDKDART KLKTSEQLDQPISSCGFNAQGNIFGYASSYDWSKGHEGYDAQK-KPHLFLRSCYEELKPS QKK--------------------------------------------------------- -------------------------SGTVCLDVINQAWTALYDLSNIFESFLPQLLTYXN PIDPLNGDAAALYLHKPEDYKKKVIEYVKKYATEEALREHESSMSDFSEDEVGDMELMDD QSILTTLKILIIGESGVGKSSLLLRFTDDTFDPELSATIGVDFKVKTITVDGNKAKLAIW DTAGQERFRTLTPSYYRGAQGVILVYDVSSKQSFTQLGNWLNELETFSTKHDIVKMLVGN KIDKDRREISRDEGLKFARKHHMLFIEASAKTKEGVQCAFEELVEKIIQTPGLWETDGLS LGRVIWSIINGTFCSFKVRTKSQKFCRNEYSLTGLCNRSSCPLANSQYATIREEKGVCYL YMKTIERAAFPARLWEKVKLSRNFEKALQQIDDNLIYWPRYIKHKCKQRFTKIIQYLIRI RKLTLKRQKKL------------------------------------------------- ------------------------------------------------------------ --------------------GVMILDALIKIKNEIDPTLTFRRSCREGICGSCSMTVDGV NTLACLCKINQNESQTTSVRPLPHMFVIKDLIPDLNNFYAQYRWIEPWLKKKDVKDAEMG QNQFMQSPEDRDKLDGMYECILCACCSTSCPSYWWNGDKYLGPAVIMQAYRWVMDSRDDF PKERMDRMRDKWMVYRCHTIMNCTKTCPKGLNPGAA------------------------ ------------------------------------------------------------ ---------------------------------------------------VPAAIPEQP PHHILFLTNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHDIXFVEFENEAQAGAAKDALQ GFKITPTNAMKISFAKKMDSQGRKVVVCDNGTGFVKCGFAGSNFPAHIFQSMVGRPIIRS SNKIGDIEVKDLMIGDEASKLCSMLEINYPMQNGIVRSWEDMNHLFDYTFGPSKLNIDPP NCKLLLTEPPMNPIKNREKMVEVMFENYQFEGLYIAIQAVLTLYAQGLLTGVVLDSGDGV THICPVYQGFSLPHLTRRLDIAGRDITNYLIKLLLLRGYAFNHTADFETVRMM------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------VAKPIEC KAAVAWEAKKPLTIETITVAPPRAGEVRIKLLATGVCHTDSYTLDGFDPEGLFPVVLGHE GGGMVESVGEGVTSVKPGDHVIPLYIPQCGECKFCRSPKTNLCSKIRSTQGSGVMPDGTS RFTCRGKQLYHFMGCSTFSEYTVVAEISVCKVDETAPLEKICLLGCGISTGYGAALNTAK VESGSSCAIWGLGAVGLAAIMGCKKAGAGRIIGIDVNPKKFEKAKEFGATECINPKDFDK PIQEVLVGMTDGGLDFTFECIGNVATMRAALEACHKGWGVSVIIGVAAAGQEISTRPFQL VTGRVWXGNGFWRLXSRDSVPKLVGXYMDGQLKVNEFVSXNLGLGXVNEAFDLLHSGESM ESYDVIANQPVVIDNGSGVIKAGFAGDQVPKHHFANYIGRPKHVRVMAGALEGDIFLGPK AENGSGIADIRYPMEHGIVXSWNDMEQIWQYIYSKDQLQTFAEEHPVLLTEAPLNPRQNR EKSAEIFFETFNVPALFISIQAVLSLYATGRTTGVVLDAGDGVTHAVPIYEGFAMPHSVM RVDVAGRDVSKYLQMLLRKEGHKFHTSAEFEIVRTIKERVCYLSLNPQKEETMKTEKTQY KLPDGSTVEVGSARFRAPELLFRPDLIGEECEGIHEVLTYAIRKSDMDLRRTLFSNIVLS GGSTLFKGFGDRLLSEVKMLAPKDVKIKISAPQERLYATWIGGSILASLDTFKKMWVSKR EYEDEGMRAIHRKTFDPHKLSKVVIHPLVLLSVVDHFNRMGKVGNVKRVVGVLLGSHRQG VLDVSNSFAVPFDEDDKDRSVWFLDHDYLENMYHMFKKVNAREKVVGWYHTGPKLHQNDV RINELIRRYCPNSVLVIIDAKPKDLGLPTEAYIAVEEVHDDGTPTSKTFEHVPSEIGAEE AEEVGVEHLLRDIKDTTVGTLSQRVTNQLMGLKGLFSQLRDIENYLEKVSLGTLPINHQI IYHLQDIFNLLPDINLREFVRSMYIKTNDQMLVVYIASLIRSIIALHNLINNKIQNRDAE KNEGKEKKMGLFFSKLWGLFTNEEHKVIIVGLDNAGKTTILYQFLMNEVVHTSPTIGSNV EEVIWKNIHFLMWDIGGQESLRSAWNTYFTNSEFVILVIDSTDRERLSITKEELYKMLAC EDLKKAAVLIFANKQDLKGAMSSAEISQQLNLTSVKDHIWHIQACCALTGEGLYQGLEWI TNHIRRQAIPTRRIVLNDASQLPADYSSTPGGTLFSTTPGGTRIIYDRAFLLECRNSPLT RSPPPNMPKIPGVTCPPTAREAQRIYKYEAPWTVYSMNWSVRPDHRFRLALGSFVEEYNN KVQIVSLDEETSEFAFRSRFDHPYPTTKLMWIPDSKGIFPDLLATSGDYLRVWRVTRLEC LLNNNKNSDFCAPLTSFDWNEVDPNLLGTSSIDTTCTIWGLETGHVLGLVSGHVKTQLIA HDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLAWNKQ DPNYLATMAMDAMEVIILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQ-- ----------------------QINQIQWSSTQPDWIAICYNNYMEILRV---------- ------------------------------------------------------------ --------------------------------------ACAQYCPKAMICIICNPVNSTV PIASEMFKKRGVYDPNRIFGVTTLDIVRSNTFISQAKGLDVSQVNCPVVGGHSGVTIIPV ISQCTPPVSFPVDERQKLSVRIQNAGTEVVEAKAGTGSATLSMAYAGARFVGSVLDGLNG EEGIVECAFVRSDETEAKYFSTPLLLGKNGVEKNLGLGKLTDFEVDLIKGAMPELKKNIQ KGEEF------------------------------------------------------- ----------------------------------SETPEGGAVGLVKNLALMAYISVGSQ PSPILEFLEEWSMENLEEIAPSAIANATKIFVNGCWVGIHRDPEQLMNTLKKLRRQMDII VSEVSMVRDIQDREIRIYTDAGRICRPLLIVENQKLLLKKRHLDQLKEREYNNYCWQDLV ASGVVEYIDTLEEETIMLAMTPEDLAEKEGAYCSTYTHCEIHPAMILGVCASIIPFPDHN QSPRNTYQSAMGKQAMGVYITNYHVRMDTLAHVLFYPQKPLVTTRSMEYLRFRELPAGIN AIVAIASYTGYNQEDSVILHEGAVDRGFFRSVFYRSYKDSESKKGMDQEEIFEKPDRNFV QGMKPGDYSKLDDDGIIAPGIRVSGDDVLIGKTLTLPENEDELEGQAKRFTKRDASLCMR RTETGVIDQVMVTLNQEGYKFCKIRVRTVKTPQIGDKFASRHGQKGTCGIRYRSEDMPFT AEGIYPDIIVNPHAIPSRMTIGHLIECLQGKVSANKGEIGDATPFNDTVNVQKISNLLHD YGYHLRGNEVLYNGHTGRKMNAQIFLGPTYYQRLKHMVDDKIHSRARGPVQILNRQPMEG RSRDGGLRFGEMERDCQIAHGAAQFLRERLFEVSDPYRVHVCDLCGLIAIANLRNNTFEC RGCXNKTQISQVRLPYACKLLFQELMSMSIAPRMM-TCVEFAGGFSFENCRRNAILEKGL KPPKVYKTGTTIVGIVFSDGIILGADTRATEDTIVADKNCSKIHYLAPNIYCCGAGTAAD TEKTTQIISSQLELHRLNTDRTVRVCTANRLLKQMLFRYQGHIGAALVLGGVDSTGPHLY SIWPHGSTDVLPYVTMGSGSLAAMSVFESRYTPGISREDGMKLVRDAIAAGIFNDLGSGS NIDLCVITKKVDYLRPYDEANKKGVRQGKYAYKKGTSCVLTETVRKVEFVVE-------- -------------------------------------------------------GTVFL KHGSELRLIPRDRVG-MAFTFAALAYIIALLFTAFLIFFVIYHIIGFDELKTDYKNPIDQ CNNLNPMVLPEYFLHLFFNVMFLFAGEWTSLLLNCPLIAYHINRYMNRPVMSGPGLYDPT SIMNADQLNRAQKEGWIKLAFYLISFFYYLYSMIYVLVSSXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------- ------------------------------------------------------------ ------------------------------------------------------------ ---SEASGFCYVNDIVLGILELLKYHQRVVYVDIDIHHGDGVEEAFYTTDRVMTVSFHKY GEYFPGTGDLRDIGAGKGRYYAVNFPLRDGIDDDCYETVFEPVMAKVIETFQPGAIVLQC GADSLSGDRLGCFNLSLRGHGRCVEYIKKYNLPLLLLGGGGYTIRNVARCWTYETSIAVG VEIANELPYNDYFEYYGPDFKLHISPSNMTNQNTPEYLDKIKTRLFENLRMLPHAPGVQM QDIPDDGIKDELTKRDPLSMTTSDKRVACDEEFYDSDDEG---------------STGAF ECNICLDTAKDAVVSMCGHLFCWPCLHQWLETRPNRQLCPVCKAGISKDKVIPLYGRGST NQQDPRDKIPPRPQGQRSEPETNTNFPGFGF----------------------------- --------------------------------MYALIYKQEQAHEDSLWSCAWAKNERDG SENIVTGGVDDLVKIWKWTSLELRHTLEGHQLGVVSVDINPQGTMAASSSLDSHIRLWDV EAGKQIKTVDAGPVDAWTISFSPDSRFLATGSQTGKINLFGVDSGKKESSLDTRGKFTLS IAYSPDGKYIACGAIDGIINIFD-------------------------IVTASDDSHIKI YDVQHANLAGTLSGHGSWVLNVAFSPDNTHFVSCSSDKTVKVWDAGSRQCVHTFLDHTDQ VWCAKYNSTGTKIVSVSEDRAVHIYDSP-------------------------------- ------------------------------------------VVEIWPYLRQEIKPTLDE LGILTPEEMGYDKPELAVEDVMDM------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------DHQSSTGHSIHMRGLPFAANEQDVIEFFKPVNPVNVVIH FNSGRASGEADVDFASHEEAKEGMKRDRASMQHRYIELF--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----TSLNSKVVSQYSSILSPLCVDAVLKVIDPKKDTNVDLHDIKVIQKLGGTVEDTELI DGMVFNQKSAGTGGPHKIEKAKIGLIQFCISPPKTDMDNQVVVSDYAQMDRVLREERQYI LNIVKQIKKVGCTVLLIQKSILRDAVNDLALHFLAKMKIMVIKDIEREDIEFVCKGLACR PVASLDHFTAETLGSADLVEIVQTGSSKIVKVTGIANPGKTVSIVVRGSNKLVLEEAARS IHDALCVIRCLVKKRALIAGGGAPEIELSIQLMEYAQGLAGVEQYCFRAFADALEIIPFT LAENAGLNPIATVTELRNRHSQGEKTSGINVRKGAITNILEENVVQPLLVSTSALQLAAE TVRSILKIDDIVICQMILLEINNRIVEETLTLKFQNAMAGMKPDSVDITVADFDGVLYHM SNPSGDKTKIQVSIALKFYKDLQEHGADDLIQRVYGSHLTDPEPGYNISLLFDENLPSNQ EEVIKKVGLLKRNCFASVFEKYFDFQTQHKRAIIHYREDETMYVDAMKDRVTVIFSTVFK DDDDVIIGKVFMQEFKEGRRRYQQAPQVLFTHKEPPLELKNTDARVGDNIGYITFVLFPR HEARDNTINLIHTLRNYLHYHIKCSKAYIHSRMRAKTSDFLKVLNRARPEQKTLEKKTFM LMFCPICANVLVIEEGPKCYRFACNTCPYVHNVTRKITDRKYPKLKEVDDVLGGAAAWEN VDSTSETCPKCSHNRAFFMQIQTRSADEPMTTFYKCCNMQCSHQWRKTSYGGLKDEDRIF TNLYGRHDWKLKGAMSRGSWYKTKEILLKGTEWIQNEVKVSGIRGRGGAGFPTGMKWSFM NRPDDGRPRYLVVNGDEGEPGTCKDREIMRHDPHHLVEGCLIAGRAIGACAAYIYIRGEF YNEASNMQIALREAYEAGLIGKNACGSGYDFDIYLHRGAGAYICGEETALIESIEGKQGK PRLKPPFPAEIGLFGCPTTVNNVETISSAPSICRRGGEWFASFGRERNRTVLMDFDALTE AQSAFGTAAVIVMNNSTDVIKCIARLMEFYKHESCGQCTPCREGVGWMEKIVSRFVTGNA RPDEIDMLYELSKQIEGHTICALADGAAWPVQGLIRHYRPQLEQRMHEYEEKHFTQEQVE EMNQQLSQTRSQRVRAAMFPETLEEGIQIPSTQIHMDQPTAVQRLAEPSQMLKHAVVNLI NYQDDADLATRAIPELTKLLNDEDQVVVSQAAMMVHQLSKKEASRHAIMNSPQMIAALVR AMSNTNDVETTRCAAGTLHNLSHHRQGLLAIFKSGGIPALVKLLSSPIESVLFYAVTTLH NLLLHQEGSKMAVRLAGGLQKMVALLQRNNVKFLAITTDCLQILAYGNQESKLIILASGG PGELVRIMRSYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMPALAMHLGHQSQRLVQN CLWTLRNLSDAATKAETIVGLLQMLVQLLVSNDINIVTCAAGILSNLTCNNQGNKVMVCQ VGGIEALVRTILQAGDREDITEPAVCALRHLTSRHPEAEMAQNAVRLHYGLPVLVKLLNP PSRWPLIKAVIGLIRNLALCPANHAPLREHGAIPRIVQLLIRAHQDTQRQQGAYVDGVRM EEIVEGTVGALHILAREAHNRAVIRSLNCIPLFVQLLYSPIENIQRVAAGVLCELAADKE GAEVIEQEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRGE QMSADLQWMXTRSNSCFLVKRSTSSREPNNLYNRHGKRASGLINQQAIGIEALXDDKGLV FVTKNNWRKPAKSTTKTILKQG-------------------------------------- ----------------------------------------------------------PP VKERLEMPVATQKTDTGLTPGLLRVLNKQLGPKKSVPLRLIEDKWKDLGLPKEQFDELTR IGGFSDTVDWLKFFSLACSALGENITDAM------------------------------- ----------------------------------------------DGAQKGQLMEQVKA QIAVANAQELLQKMSDKCFKKCVSSPGSSLGNSETKCIAMCMDRYMDAWNVVSRAYTQRL QRERNK-MNRLFGRGKPKEPAPNLTDCIAGIDSRGESIDKKISRLDQELNKYKDQMKKMR DGPSKNMVKQKAMRVLKQKRMYEQQREQLMNQSFNLEQSNFQIQTMKDTKTTVDAMKTGV KEFKREYKHVDIDQIEDLQDELEDMTEQAGEIQEIMGRSYGMPDVDEDDLEAELDALGDE MALDEDTSYLDEAAKAPSAPTXVPGAASEASQDGVPVDEFGLPQIPAQMTPLNPATPASP QLQNIVCTVNLVC----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------VCLGPWEPHGSSWYNCNRY DEDEAKKARDSQEKSRSALQRYLFYCNRYMNHMQSLKFESKLYASIRLKMEEMQQHNMSW IEVQFLKKAVDVLCQCRQTLMYTYVFAFYLRKNNQSIIFEENQKDLENSTEHLSEYLERD ITSDMLVDIKQKVQDKYRYCESRRKVLLDHVHEGYERELWDYLDMATTDGKLSTTERIIK SVPFPPNHKLTMQEVFDPKAKPKPDILKQHFIVEGRVTEDVALRIINEGAALLRQEKTML DIEAPVTVCGDIHGQFYDLMKLFEVGGTPSTTRYLFLGDYVDRGYFSITERVYDACMEAF DCLPLAALMNQQFLCVHGGLSPEMHTLEDLRKLDRFKEPPAFGPMCDLLWSDPLEDFGSE KTTEHYSHNSVRGCSYFYSYAACCDFLQQNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSL ITIFSAPNYLDVYNNKAAILKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVT EMLVNVLNICSDDELMSEGDDTFEGTVAARKEIIRNKIRAIGKMARVFQVLREESESVLQ LKGLTPNGLLPIGALSGGKESLTTALSGFSPTHKISGFVEAKYLDKMNERMPP------- ------------------------------------------------------------ -----------------------------------------------------------A ASGTTVSHVADIVGPEGLVYAVEFSHRSGRDLINVAKKRTNIIPIIEDARHPHKYRMLVG MVDTIFADVAQPDQARIVAINAHNFLKTGGHVVISIKANCIDSTAAAEAVFASEVNKLRA EKIKPREQITLEPFERDHAVVVGQYRPPPKKMDKNKLSDLAGRLQKGGKGAGIGAGLIAA AGAAVYGLYQSFYTVDGGHRAIMFNRIGGVQQSIYSEGLHFRLPWFQYPIIYDIRARPRK VTSPTGSKDLQMVNISLRVLARPNVSKLPELYRQLGTDYDDRVLPSLCNEVLKSVVAKFN ASQLITQRQAVSLLMRKELTERAYDFHIILDDVAITDLAFSNVYTAAVESKQVAQQESQR AQFIVEKAKQERQQKIVQAEGEAASAKMIGEAVAANPGYLKLRKIRAAQNIARTMAMSKN RVYLNAGTLMLNVNDKDFDESLQSYTGSSSDEEATNPKEKEQSNSKGCSDFCVHVAQAAF GRREIEIAQQEMPGLMALRKRAQADKPLSGAKVVGCTHITAQTAVLIETLSALGAQVRWA ACNIYSTQNEVAAALAEAGFAIFAWKGESEADFWWCIEKCISADSWQPNMILDDGGDATH LMLKKYPAMFSLVKGIVEESVTGVHRLYQLSKSGKLTVPAMNVNDSVTKTKFDNLYSCRE SILDALKRTTDVMFGGKQVVVCGYGEVGKGCCAALKGLGAIVNVTEIDPICALQACMDGF RVVKMSEIARTTDLIITCTGNKSVVTREHMDRMKNGCIVANMGHSNTEIDVNSLRTADLT WERVRSQVDHIIWPDGKRIILLAEGRLVNLSCSSIPSFVVSITSATQALALIELYNAPAG RYKQDVYLLPKKMDEYVASLHLSSFDAHLTELSDEQAKYLGLSKAGPFKPNYYRYPDPDA IKMFVGQVPRSMDEEDLRKMFEEFGPICQLNVLRDKVTGMSKGCCFVTFFTRKAALEAQN KLHNIKTMTGMQHPIQMKPADSEKRSIEERKLFLGMLSRKCSENDVRMMFSPFGTIEECT VLREPNGQSKGCAFVTYASKQCAQNAIRGMHQSQTMEGCRSPLVVKFADTQKDKEMKKLQ QMNNLAALQ---GGLGGSMCSAFGHPLDTIKVRLQTMPXMYSGMLDCTKKMFLKEGIRGF YKGMGAPLIFAVSFFGFNV-GKAIQVAGVFSTSIMAPGERIKCLLQVVVKQLFKEGGIRS IFKGTNATLLRDVPASAMYFMSYEWLQRILTPEGHSRTELSPRTMFAGGMAGVFNWLVAI PPDVLKSRLQIAKE-----------------------------------DNSNEFTRLSQ VIANNIQKITQNVAQMQRLVNQIGMRQDSVELRDKLHQVQHYSNQLAKDTSKYLKDIAHL PSEQRQRKMQRERLMNDFSSALNNFQAAQRLAAEKEKQSVEDVDIQLLQEREQAIKQLES DITDVNQIFKDLAVLVHEQGEVIDSIEANVDAVHVDEGTQQLSKASTYQTKARRKKCFLI IILLVVLAVIGLIIGLTVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXGKKGEAPPSPQEAIQRLRGIEEMLQKKTDFLEK KIEQELSIARKRVALQALKRKKRYEKQLTQIDGTLSTIEFQREALENSSTNTEVLKVMGD AAKALKTAHKNMDVDDVHDLMDEVAEQQEIANEISEAISSPVGFGQDVDEDDLLAELEEL EQEALDEQLLEVGELPSVPTAEEDEMKELAQWAS-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------RXTMIXPPRXVEGILEHTLFKGTYFPTWEGLFWEKASGFEESMKYKKLTN ATKDTMDSTTTQKFWLDIQLRWGDYDSHDIERYTRAKFLDYTMDNMSIYPSPTGVLIAID LAYNLHSAFGNWFPGAKPLIQQAMGKIMKANPALYVLRERIRKGLQLYSSEPTEPYLSSQ NYGELFSNQIIWFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSV WAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKG SELQLPFQACLKVEKFGDLILKATEPQMVLFNLYDDWLRTISSYTAFSRLILILRALHVN NDRTKIILKPDKTTVTEPHHIWPTLTDEEWIKIEVQLKDLILADYGKKNNVNVASLTQSE IRDIILGMEISAPSAQRQQIAEIEKQTKEHSQLTATTTRTVNKHGDEIITSTTSNYETAT FSSKTEWRVRAISATNLHLRTNHIYVSSDDIKETGYTYILPKNVLKKFIIISDLRAQISG YLYGVSPPDNPQVKEIRCIVMPPQWGTHQTVHLPNQLPQHEYLKEMEPLGWIHTQPNELP QLSPQDITTHAKVMADNASWDGEKTVIITCSFTPGSCSLTAYKLTPSGYEWGRQNTDKGN NPKGYLPSHYEKVQMLLSDRFLGFFMTPSQCPWNYNFMGVRHDPAMKYEVTLTNPKEFYH EVHRPSHFLNFSSLEESADHEDFY-------------------------KQGTYHSEQAL EYGTNMVGGVSPGKGGKIHLGLPVFNSVKEAKEGTGADVTVIYVPPPFAKDAILEAIEAE IGLIVCITEGIPLHDMVRVKYKLVRQSHSRLIGPNCPGIIKPGQCKIGIMPGHIHKPGSI GIVSRSGTLTYEAVQQTTDVGLGQSLCVGIGGDPFNGSDFIDCLSVFLNDPQTEGIVMIG EIGGEAEEMAAKFLIENNGPDAKPVAAFIAGMTAPPGRRMGHAGAIIAQGKGGAQEKIQA LRDAGVEVTMSPAQMGSSIYKAMVKAGKPNTETLKCTLCLERLEDTHFVQCPSVPEHKFC FPCSRDSIKSQGAGSEVYCPSGKKCPLVGSNVPWAFMQGEIATILGFNRFVEIGRVAYVA FGPDEGKLVVIVDVIDQNRALVDGPCSGVGRKSMNFKQMHLTKFVVIPPGARVGTLKKAW EKQEMTKKWEETTWAKKIAQRDLKTGLTDFDRFKLMKAKQSRNRLINIQLGKLKKQMRKT CPLLLRVFCSTGRHHPLNEYARGNTPANELQIYTWLDATLKELTSLVKEVNVDARKKGTF FDFAIVYPDPRTPVYRMRDIGATCAGRKGMD----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TAD IVILYDSDWNPQVDLQAMDRAHRIGQKKQVKVFRFITENTVEDRIVEKAEMKLRLDNVVI QQGRLTDAST-KEVLSMIRHGANHVFASKESDITDEDIDAILARGEKKTEEMKKKLEGLG ENTSSPSPSTPRTXSVYQFEGEDYRGKQKI-GIGNWIEPPKRERKANY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------EVKPSWAEQVEWGEDETLPPAREDYDEKT KTKTVTEYTYNSESKKVKVVRTYKIETRKVAPSIAKRKAWKKFGSASNDAPGPNPSNTIE ETFMQFVHSKENAEEDPLAKLKVSCRICKGDHWTTKCPYKDTLAPPQENAPRXGKYVPPN MRDGGNRRGETMMGDEAATIRVTNLPEDTIEADLQELFRPFGSISRIYLAKDKATGQSKG FAFINFHRREDAARAIAGVSGFGYGHLILNVEWAKPSMSETYDFLFKFLVIGSAGTGKSC ILHQFIENKFKQDSNHTIGVEFGSKVVNVGGKSVKLQIWDTAGQERFRSVTRSYYRGAAG ALLVYDITSRETYNALTNWLTDARTLASPNIVIVLVGN---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------HLGLILGVGGQMQELRRVRSGILSEKDGMMTMHDVLDAQWQYD HMQDETYLRRVIRPLEALLISHKRIIMKDSAVNAICYGAKIMIPGVLRYDDGIEINDQIV ICTSKGEAVALAIAQMTTAVLATCDHGVVAKIKRVIMERDTYPRKWGLGPVASRKKQLIK DGKLDKFGRTNENTPKDWSKSYKDLS----------------------XXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXX--------------------------------EGKKRYTDYEVHMRTN LPVFKVKESSVRRRYSDFDWLRGELERDSKIVVPPLPGKAWGRQLPFRGDEGLFEEEFIE ERRKGLEQFVNKVAGHPLAQNERCLHMFLLEPVIDKNYIPGK----RKYSARLMEVGVLE SPRLQGKYDTGQLFLHKVFGYRGVVLFPWVGKVYDRDIAVKASKEVKGCTHTYYQVLIDA RDIPHIRVGTESVTFLSNQENGTLYSIPGLDYVSHEDVLPYKTTEGQPIHNHLFDKFLDH DTTYVARDTLREWQDKNHPWLELTDVHRETTENIRVTVMPFYIGEVQQAHVYWWRYCIRL ENLGDEAVQLRERHWRIFSLSGTLETVRGRGIIGKEPIFSKAQPAFQYTSHVSLQAPSGH MWGTFKMEREDGTTFECRIPPFSLESRQEEGMATSKGANSYNRQNWEDSEFPILCQTCLG DNPYIRMTKEKFAKECKICARPFTVFRWCPGARMRFKKTEICQTCSKLKNICQTCLLDLE YGLPVQVRDAALKIADEMPRSDV------------------------------------- ------------------------------------------------------------ -------------------MDVFLMIRRKKTTVFMDAKESTPVLEMKKMLQGITKKLPED MRLFKDHKTLGDCGFTSSTARAQAPATIGLSYKDFEQLEVAPLSTPPELPDVMKPTESTS AHKQEHTYRYQAVLMRARFDEHTSEDMVKAKKLVLDGEKELFLKQHPQRIRFANSVGGVS FGREVLQPDWTLDMWHPLERQQYPEYFARREQRKKEYIKRWEDKYG---MDDYIKIEKIG EGTYGVVYKGRHKKTNRTVALKKIRLESEEEGVPSTAIREISLLRELTHPNIVCLEDVLM QENKLYLVFEFLSMDLKKYMDSIPSGQFMDSMLAKSYTYQILQAILFCHKRRVLHRDLKP QNLLIDSNGVIKLADFGLARAFGIPVRVYTHEVVTLWYRAPEVLLGSSRYSTPVDIWSIG CIFAEMITKRPLFHGDSEIDQLFRIFRTLTTPTEEAWPGVSSLPDYKSTFPCWKTNTLAQ AVDVNGMDLLQKTLVYDPAARITAKDALLHPYFAARVFNSLGRVGLGIAVLGGVVNTALY NVGGGHRAVIFDRFAGVKDVVTGEGTHFLIPWVQKPIIYDIRSRPRSVPTVTGSKDLQNV NLTLRIIFRPMASELPKIYKTLGIDYDDRVLPSIVNEVMKAVVAQFDASELITQREVVSQ KINEDLTNRASQFGLILDDISITHLTFGTEFTQAVEMKQVAQQEAERARFVVEKEEQKKQ AAIIRAEGDSIGADLLAKAFGLAGEGLVELRRLEAAEDIAYQLSQAPNVVYLPSGQQTLL SLPMKTIKVNQVVTIPKNVTLTVKSRSVTVKGPRGTLRRNFRHMAVDMKMIGKNKLQVEK W----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------NDSAEYYLNALDRISQPNYIP TEQDVLRTRVKTTGIVETHFTFKELHFKMFDVGGQRSERKKWIHCFEGVTAIIFIVAMSE YDMTLAEDQEMNRMMESMKLFDSICNNKWFTDTSIILFLNKKDLFEDKIRKSPLTICFPE YSGSNTYEEAAAYIQMQFNK---------------------------------------- --XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXMSFTSDEVNFLVYRYLQESGFSHSAYTFGIESHISQSNINGALVPPAAL LSIIQKGLQYTEAEISIAEDGSERVIETLSLIDAVMPDMVESRKQVAAGATNGEEHSEAM EIDGSVEIPSSKATVAEGHESEVFICAWNPTNDLLASGXGDSTARIWNMNNNSNANQLVL RHCIQXGGTEVPSNKDVTSLDWNCDGQLLATGSYDGYARIWNTDGRLVSTLGQHKGPIFA LKWNKKGNYILSAGVDKTTIIWDASSGHCTQQFAFHSAPALDVDWQTNTSFASCSTDQCI HVCKLGVDKAIKTFQGHTNEVNAIKWDPXGNLLASCSDDMTLKIWSMKQDNCVHDLQAHN KEIYTIKWSPTGPGTNNPNAPLILASASFDSTVRLWDVEHGVCIHTLTRHQEPVYSVAFS PDGAFLASGSFDKCVHIWNVQSXALVHSYKGTGGIFEVCWNHHGDKVGASASDGSVFVLD LRK--------------------------------------------------------- --------------------------------------------GASCKWQGALEQVMPH LMQQHKSITTLQGEDIVFLATDINLPGAFGWVMMQSCFGQNFMLVLEKQEKYECNQLFYA IVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHDGVQLAINNSDCLVFDTNIAQLF ADNGNLGINVTISTCMAYQSFQQEYMQMPPVTRAYTTACVLTTLAVQLDLITPFQLYFNP DLILRHYQLWRLVTNFMFFGTIGFNFLFNMIFTYRYCRMLEEGSFRGRTADFFFMFLFGG FLMTVVVNLVFLGQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPYLPWVLLAFSLLLGNS VVVDMMGIAIGHIYYFLEDVFPEQAGGFKILVTPQILKKIFDAQPDDPSYNPLPPGGFAW G-SLRLLSDEGFRIDGRRPNELRRIQCRMGVFAQADGSAYIEHGNTKVLAAVYGPHDIQG SKGRHDIAFINCQYSMATFSTGERKQRPRGDRKSQEMTHHLKQTFDGAILTHLYPHSQID IYVEVLQSDGGNYCASVNAATLALIDAGIPMKDYVCACSASFIGETPXMDINYTEESSAP QLIVSILPKSEHLVFVEMNSRLHEDQLSRVLDIAVKGCSDIYHILDRAVKEMSGNYYFVI VGHHDNPIFEMEFMPPSKANESKKDDHRHLNQFIAHAALDLVDEHMWATSGMYLKIVDKF NEWFVSAFVTASRMRFVMLHDTKNEDGIKNFFQDVYETYVKYAMNPFYELNAPIKSAAFE KKSQFFGRKYL--QVRFAHTDLQVPDFSAYRRDGTKEARKAFTYMMLAASCVPATYGAKA MVVEFVSSMSASADVLALAKIEVNLADIAEGKNVTFKWRNKPLFIRHRPAEEIAREEAVP LSDLRDQETDSQRVQKAEWLVVLGICTHLGCVPIANAGEYGGYYCPCHGSHYDASGRIRK GPAPTNLEIPPYIFTSETTITVG------------------------------------- --------KMGYNIGCRLIEDFLARSSVGRCYDFKETADVISKVGFKMYLGITPVVTNWS ATGDEFSLLLENNPLTEFVELPEGHSNLNYSCLLCGVLKGAMEMIQMEVAVWFVQDQLKG DNVTEIRVKFVRRLEDAVPAGEDDNVKAXLGTARD---HKMDEPAHNTACLDDFERHKTL GTGSFGRVMLVQHKSSKDFYAMKILDKQKVVKLKQVEHTLNEKRILQAISFPFLVKLEYS FKDNSYLYMVLEFVTGGEMFSHLRRIGRFSEPHSRFYAAQIVLMLEYLHHLDIMYRDLKP ENLLIDVLGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVY EMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRSLLQVDLTKRFGNLKNGVN DIKTHRWFSTTDWIAIYQKKVEAPFIPKVKGPGDFSHFDDYEEEPLRVSSTEKCAKEFAD FMYADTLLILFISVATAVFGEGLTWLLVYRTEKYKKLKAEVEKQSKKLEKQKEMVVDTTE RSHKKKLERQEERLKTNNRDLSMVKMKSMFATGFAFTALLSMFNSIFDGRTVAKLPFVPI SWLRSISHRNLMGEDYTDCSFIFLYILCTMSIRQNIQKLLGFAPTRAASKQGSGFFGT-- ------------------------------------------------------------ ------------------------------------------GLAERRGWDSF-YQAKPG NXQKDHKFYRRLYPQIISDIDRIENNWRTGHHTLQRIHCRSETSKGVYCLQYDDLKIVSG LRDNTIKIWDRGSLECVQVLTGHTGSVLCLQYDENIIVSGSSDSTVRVWSVKTGEMINTL IHHCEAVLHLRFCDGIMVTCSKDRSIAVWDMQSPTDINLRRVLVGHRAAVNVVDFDQKYI VSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACL RVLEGHEELVRCIRFDNKRIVSGAYDGKVKVWDLTAALNPRAPAGTLCLRTLVEHSGRVF RLQFDEFQIVSSSHDDTILIWDFLNMAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNS TFISTIGIDFKIRTIEMDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIML--------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------GLVIYCGT IVTDEGKEKKVNIDFEPFRPINTSLYLCXNKFHTEALTALLADDNKFGFIVMDGNGALFG TLSGNTRDVMHKFTVDLPKXHGRGGQSALRFARLRLEKRHNYVRKVAEVAVTLFISNDRP NVAGLVLAGSADFKTELSQSDMFDPRLQAKILKIVDVSYGGENGFNQAIELASESLANVK FIQEKKLIGKYFDEISQDTGKYCFGVDDTLKALEMGAVEILIVWENLETMRYMLKNHQTD EEKILYLRPEQEKDKTHFTDKDTGVEMELVDSQPLLEWFANNYKTFGATLEIITDRSQEG AQFVRGFGGIGGILRYQVDFQMMEPLDDLEDDFDLDDYITRSSQPLVGKRSKDDERYIQM IMDANAQSHKLYIMDARPSVNAVANKARGGGYESEDTYQNAELVFLDIHNIHVMRESLRK LKDVCFPTIDDAHWLSNIEATHWLDHIKQILAGAVRIADKVETSKTSVLVHCSDGWDRTA QLTALSLLMLDPYYRTVRGFEVLIEKEWVSFGHKFAQRVGHGEDKHSDADRSPVFLQFID CVWQITRQFPNAFEFNEHFLMVVLDHLYSCLFGTFLGNCDMQRFKEGVRDKTVSLWSYVN CQLEEFTNPLFQHVLFPVASLRRIELWTGYYVRWNSRMRPQEPLHLRNRELLQLKAQLQR RVDELSLELDAK------------------------------------------------ ------------------------------------------------------------ --------------------------------MNEGGCEISSADATVRMLITTIPPNLKK LDPEIHLDAKLMQQHLVSIRHTRWFEENASHSSIKVLIRLLQDLRGRFDGFLPLTAWIID LLAHYAIMVNPKREPLPLHVSFRRCLQLLSAGFFLPGS-GITDPCEQGSVRVHTIMTLEQ QDQVCYTAQTLLRVLSHGGYKQILGLEGNAGIATEMSVWEGVVVTPSDKAFEKVEK---- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------GKAAV KEQEDEKYPTQLSKTIKFGQXAHIECARFSPDGQYLVTGSVDGFIE-------------- --AQDNYMMMDDAVLCICFSRDSDMLATGGQDGKIKVWKIQTGQCLRRFERAHTKGVTSV YFSRDNSQLLSASFDQTVRIHGLKSGKTLKEFRGHTSFVNDAIFAADGHHIISASSDGTI KIWNIKSTECQNTFKSLGGTSGSDITVHSVHPLPRNVEQFVVCNRSNTVV---------- ------------------------------------------------------------ --------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------RVYGQYLNLDKDHNGMLSKE ELARYGTGTLTPVFLDRVFQECLTYDGEMDYKTYLDFVLALENRKEPQALQYLFRLLDIQ KKGYLNIFDINYFFRAIQEQMRTHGQEPVAFDDVKNEIFDMVKPTDALRITLQDLLRCGQ GNTVTSILIDLN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------KICDFG LARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYSKAIDVWSVGCILAEMLSNRPIFP GKHYLDQLNHILGVLGSPTQEDLNCIINEKARGYLQSLPYKPKVPWNKLVDPKALDLLDK MLTFNPHRRITVEEALAHPYLEQYYDPQDEPVAEKPFTFETELDDLPKERLKELIFQETI HLREKELSPPKTTPEWVKFCKQLFGGFSTLLWIGAILCFVAYTIQSTKQEDVPGDNLYLG IVLTCVVIVTGCFAYYQEAKSSRIMDSFKNLIPQFALVLRNGDKLNLHAEELVVGDVIEV KFGDRVAADIRVISAHGFKVDNSSLTGESEPQSRSPECTSDNPLETKNLAFFSTNAVEGT CRGLVIATGDRTVMGRIANLASGLEVGKTPIAHEIEHFINIITGVAVFLGVSFFVIALVL GYNWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTI CSDKTGTLTQNRMTVSHMWFDNNIVEADTSEEQTNASYDTSSQTWQSLSTVAMLCNRAEF KVNQQNIPVLKRECNGDASESALLKCVELSIGNVTEFRAKHKKVCEIPFNSTNKYQVSVH PASSEYLLVMKGAPERILDRCSTIMINGKDEEMTQEWRDSFNQAYLDLGGLGERVLGFCD FNLPVDQFPSSYPFDSDAENFPLTGLRFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVT GDHPITARAIAKGVGIISEGNETVEDIAARLGVPVSKVNPRDAKACVVHGSDLRDMTPAQ IDEILFYHTEIVFARTSPQQKLIIVEGCQRQGQIVAVTGDGVNDSPALKKADIGVAMGIA GSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLVFILAD IPLPLGTITILCIDLGTDLVPAISLAYEQAESDIMKRQPRDPKHDKLVNDRLISMAYGQI GMIQASAGFFTYFVIMAENGFWPSRLLGLRKEWDSKSVNDLEDSYGQEWTYAQRKVLEYT CHTAFFMAIVIVQWADLMICKTRRNSIIHQGMTNHHLTFGLFFETTLAAFLSYCPGLDKG LRMYPLHFTWWIVPMPFSLAIFVYDEVRKYQIRRSPGGWVERETYYTIARLSRGKKIAAG VTAGAIGLGVALQELELHPPAYPWTHNGAFSSFDHASLRRGYQVYKEVCAACHSMKYMAY RELVNTIFTEDEAKKEAEQITVIDGPDDEGKMFERPGKLSDYFPSPYANDEAAKAANNGA YPPDLTYIVSARHGGEDYIFSLLTSYCDPPAGIEMREGLYFNPYFNGGAIAMAQSIFNEV VTYDDGTNPSASQLAKDVSAFLKFASEPEHDERKRMAMKAILGFLFVTVYYYKRHKWASL KSRKIVWMRPDLPSRCTYKLGVIEESPHLHHKSNLSVLPNILQAIGETPLVRINKIGASA GLQCEILAKCEFFNAGGSIKDRIGLRMVEDAEASGRLKPGSVLIEPTSGNTGIGLALAAA VKGYRCVIVMPEKMSLEKVDILRALGAEIVRTPTSASFDSPESHISVAQRLLDEXPNSII LDQYRNPXNPLAHYDGTAEEILQACNDKVDMVVLGAGTGGTMTGVSRKIKERCPNCKIVG VDPLGSIIAVTEDKTMYEVEGIGYDFVPTVCDRSLVDKWYKSEDKASFIMARRLIREEGL LCGGSSGSAMYCAIEAAKDAGLKEGQRVVVILPDSIRNYMTKFLSDEWMRSHDFMSDAGS DEETGPYLGEYEGERNERDERHGQGKATLPNGDTYEGLYECGKRHGQGTYRFKNGARYIG EWVNNKKHGQGLFIYPDGSKYEGSWVEDQRSGNGKYSYINGDYYDGEWQNHVRHGQGTYV YADTGSKYTGTWKDGKREGQGEFIHANHKYVGPWKGDVMEGTGKYVFDIGCQQHGVYIXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXSVESVMFYLPANTKRCLKEEIHKDVLVTGEYALSEGPGQKTNL RVTDAKGHILYNKEDASTGKFAFTTEEYDLFEVCFESKMAGGGRGADREVTLRIKHGVEA KSYENLAKAEKLKPLEIELKKLEDLSQSIVNDFAYMRSREEDMRDTNESTHSRVLYFSIF SMCCLIGLATWQVLYLRRFFKAKKLIEEKESGRTSSVGNDILGFCGNVVNKPEHGHLDWI KICQQASKVITFIDLAGHEKYLKTTVFGMTGHAPDFSMLMVGANAGVVGMAKEHLGLALA LNVPVFVVVTKIDMCPVNVLQDTLKMLQRILKSPGCRKIPVLVQSMDDVVVSATNFTSER MCPIFQVSNVTGENLDLMKMFLNLLSTRLVTAPAEFQIDDTFSVPGVGTVVSGTTLRGLI RLNDTLLLGPDALGQFLPIVIKSIHRKRMPVLEVRGGQTASFSLKKSQIRKGMMMLSPRL EPTACWEFEGEILVLHHPTTISVKYQAMVHVGSVRQTATIICMTKEHLRTGDKATVRFRF IKNPEYLKKDMRMVFREGRTKAVGTITHIFPHVSMNTRQNRAAKKAVE------------ ------------------------------------------------------------ ------------------------------------------------------------ ---LCTLNGHSAEIISLSFNTTGDQLITGSFDHTVSVWDTRLHTLIGHRAEISSTQFNWD CSLVATGSMDKTCKLWDATTGQCIGTLSGHEDEVLDVTFDYTGQYLLTASADRLYNVATQ AKLEGHEGEISKVCFNPQGTRILTASSDKSARMWEVDSGQCSQILEGHTDEIFSCAFNYE GNTIITGSKDNTCRIWR------------------------------------------- ------------------------------------------------------------ ---------------------------------------------------------GVK YTNNEAYFDVIEEIDAIIDKSGSTVFAEVQGYIDCLVKLTGMPDLTLSFVNPRLLDDISF HPCVRFKRWESEKILSFVPPDGSFRLISYHIGAQYIAAIPVYIRHHISFRETGQGKLDIT VGPKQTMGKPIENVILEIPFSKSVLNVMLTVNQGKYSFDPVTKVMTWDVGRIDSTKLPSI RGTIKLQSGCPAPDSNPIISVQFSISQLAASGLKVNRLDMYGEKYKPFKGVKYLTKAGKF QVRTMATCEKPATRYGTSDWFTSNYAISTNAERQRGASHDIRQEARFLRNETDNKTKWDQ LDTNTRLSDRVDHIRQWKDILDRTLAKLDQEIKDLSDAKDDLEVALENMNLPCHVNIENL TTREGRMDIDVVEDAVEDQLKKEQKVIEGIKQQLQQNIHQAFEQLCVLQEARQQVLADLQ DKNVALGIDVDQYNLTDESSEISFKPDPTRVMKGSTTPQQWEDFSRYNHDRAVAEMSNSQ HLREAIFATLEQTANDLKSQDNATDYALRKRMHEMQMAIDELNWQKQQTEDEIAELETEI RRLVDAIRAKINPTKLAETRLENRTYRPNVELCRDNVQYGLTDEVKQLYASKASLEEKLR QSQHALDGLEKKLHRINEDLHCKTNSLKLDEMCVQNRSKL---------TNLKDVMANLV PEFQKTVKEFRSKHGNTKVGEVTVDMMYGGMRGIKGLVTETSVLDPDEGIRFRGYSIPEC QKLLPTVAGGKEMLPEGLFWLLLTGDIPTDAQVKAVSKEWANRADLPAHVVTMLKNFPST LHPMAQFSAAITACNHDSKFKQAYTEGVRKNVYWEYFYEDAMDLIAKLPTIAALVYRNTY KNSSSICPIDTDKDWSFNFTKMLGYDDAQFTELIRLYLTIHSDHEGGNVSAHTCHLVASA LSDPYLSFGAAMNGLAGPLHGLANQEVLVWLDGCVWTEQDLKNYVWNTLKSGVVVPGYGH AVLRKTDPRYTCQREFALEQMPEDPGFKLVSAVYKVVPDILLEQGKAKNPWPNVDAHSGV LLQHYGMTERNYYTVLFGVSRALGCMASCIWDRALGLPLERPKSLSTEHLMKM--XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXX--------------------------------------------------- --------------------------------------------------TTACVRGGCG CGVIIDALKQKLGINVGETT---------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------RLLGTPSEETWSGLTQLPEYKPYPVYNVQQQVVPNL PTKGRDLL--------------------------------ESKFFTYDGPNPKLTYPLKD VCDGWPLEYVEHHPNYEKAKEWMEKNLSDDLLELYLKRQSRGGRGMIKTKKKQDPQRVCL SRAPRGKKKYVTVITGLATYDINLKTASKFFASSFSCGSSVTGDDEIVIQGDVKDDLFDI ISEKWPQIDEECIDDLGDMKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXX------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------VQTLQRTVPCAVPGITFLSGGQSESDA TVNLNAINQRPWALTFSYGRALQASVLAAWGGKQDNLKSGQAELVKLAEANGLAAMGQFT GGT--LANQSLFVADHKYYIQSLPKVVKRRIKALKKLQFEMIKIESTFYEEVHALECKYA TKYTPLVEKRQEIVTGNIEPTDSDCDWPSDDEEGEDKAKVEEEEDPVGISEFWLTIFKNI DMLSDMVQEQDEPILKHLRDIRVKLSMGFTLEFYFDENEFFTNTMLSKEYIMRSEPDKDE PFGFEGPEIVKCKGCTIDWKKGKNVTVKVIKKMQKHKGRGTKRTVTKTVQNDSFFNFFGP PTVPDGEPDEETEALLAADFEIGHFIRERIVPRAVLYFTGEALDEEEEGDDDEGD----- ------------------------------------------------------------ ------------------------------------------------------------ ---------------DPKEQRSLLEKCASTALSSKLVAQHKEFFSKMVVDAVMMLDELLP LNMIGMKKVQGGALEDTQLVAGVAFKKTFSYAGFAMQPKKYQNTKIALLNIELELKAEKD NAEIRVDNVKEYQA---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------DATNILNKLRQKHAGMWYGVDIVSEDITDNYVSCVWEPA IVKINAIVAASEAACLILSVDETIKNPKHAQEGAPPGRGRGRPMXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMPNIKVFSGNSHQDLAQKIVDRLGIELGKVVTKKFSNQETCVEIGESVRGEDVYIVQ SGCKEVNDMLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSPISAKLVANMLSVA GADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENIVEWRNSIVVSPDAGGAKRVT SIADKLNVDFALIHKD-EKPNEVACMVLVGDVTNKVAIMVDDMADTCGTVCHAAEKLFEA GATKVYAICTHGILSGPAVSRINNSMLEAMVVTNTIPQDDKMKVCNK------------- -------------------LSCRFYEHKFPRVXDVVVVTVTSIAEMGAYVXLLEYNNIEG MILLSELSRRRIRSINKLIRVGRDECWSSLXVGQRQGYIDLXRRRVSAEEVVKCEEKFAK GKCVNSILRHVGELLNYESDDQLEELYQKTAWYFDKKYGKTGSSYEAFKLAVTNPEVIDE CDLDDHTKRVLLSNIKRRLTPQAVKIRSDIEVACYEYEGIDAVKAALKQGISMSTEDMPI KINLIAPPLFVVTTQTLERTEGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMLGNLHSDMSRQGVTTVPKGHCAACAKP IVGQVITALGKIWHPEHFTCCHCKQELGTCNFFERDGRPYCETDYHNLFSPRCAHCQGPI LDKCVTALDLTWHPEHFFCAQCGRTFGEDGFHEKDGKAFCREDYFELFAPKCGGCSRPIM DNFISALGRQWHPECFVCQECHTMFGTGSFFDHEGMPYCETHYHARRGSLCAGCHKPITG RCITAMYKKFHPEHFVCAFCLRQLNKGTFKEQNDKPYCHPCFVKLFMRPLTAEETKLLFE KLSKYIGGNIKLLIDRPDCTYCFRLHRDRVYYLSETLMKYASCVGKDELISFGTCFGKFT KTQKFRLHITALEFLAPYAKYKIWVKSSAEQQFLYGHHIMKSGLGRITEGTTQYQGVVVY SMNDLPLGFGVAAKSTQECRQADPMTIVCFHQADVGEFIRSEDTL--------------- -----------------------VSPPAVYLDYVRQKLIGVAAQNCYKVESGAFTGDISP AMIKDIDCGWVILGHSERRHVFGESNALIGEKVKHALEAGLSVIPCVGEKLEEREAXETE EVIFTQMKAKDWSKVVIAYEPVWAIGTGKTATPEMAQEVHASLRKWLTEKVKPDVAKSVR ILYGGSVNAKNCKELAKQPDIDGFLVGGASLKPEFIDIINAREREGLLDPAWEKQQKKTF TAWCNSHLRKAGTQIDSIEEDLRNGLKLMLLLEVISGEQLPKPDRGKMRFHKIANVNKAL QFIESKGVKLVSIGAEEIVDGNLKMTLGMIWTIIVTNFHNSFKDGLAFCALIHRHRPDLI DYSKLSKDRPVENLNLAFDVAEKFLDIPRMLDAEDMVNSVKPDERSVMAYVSSYYHAFSG AQQAETAANRICKVLKVNQENERLMEEYERMASDLLEWIRRTTPWLENRTTDNTLPGTQQ KLEEFRDYRQRHKPPKLEEKAKLETTFNTLQTRLRLSNRPAYMPTEGKMVSDITNAWKGL ERAEKGFEEWLLSELQRLERLDHLAQKFRHKCDIHEEWTFGKEDLLQAQDFKQCRLNELK ALKKKHEAFESDLAAHQDRVEQIAAIAQELNALDYHDAAAVNTRCRRICDQWDLLGTLTQ QRSTALVEAEKILERIDQLHLEFAKRAAPFNNWMDGAKEDLVDMFIVHTTEEIQGLINAH EQFKQTLGEADKEFQAIIALVQEVTRLAQQYGISGVNENPYTTLSAQDITGKWRDVQRLV PVRDSSLQQEMAHQQNNERLRRQFAQKANLVGQWIERHLDAVASIGVQKGSLEDHLNKLK GVEKEVLSFKPNIDELEHYNQEVQEAMIFENKHTQYTMETLRVGWEQLLTSVARNINEVE NQILTRDSKGITNDQMDEFRKSFFHFDRNRTRRLEPKEFKACLVSLGYNIRDDRQGEADF QRIMSIVDPNNTGAVTFDSFLDFMTRETTDTDTAEQVMQSFRILAGDKPYITGDILRREL PPDQAEYCIQRMAPYGGRDAAPGALDYTSFSTALYGESDLNKLSIDKVNLKDKRVLMRVD FNVPLKDGQITNTQRIVAALPTIKYALDQGARSVVLMSHLGRPDGQPNPKFTLQPVADEL PKVLGKPVTFLKDCVGAEVEAACASPKPGTVILLENLRFHIEEEGKGVGADGKKLKADEA AVKTFRASLSKLGDIYVNDAFGTAHRAHSSMVGCQLPQKASGFLLKKELEYFAKALDKPE RPFLAILGGAKVADKILLIESLLDKVNEMIIGGGMAFTFLKVINNMEIANSLYDDEGAKL VKGLMEKATKNKVQIHPETDKVTGDKFAADAKVGTATVETGIPSGCMGLDVGPATVKTFT AVILKAKTIVWNGPPGVFEFDNFAAGTKGMMDAVVAATEKGTISIAGGGDTATCCVKFKT EDKLSHISTGGGASLELLEGKILPGVAALSDA------KSWQPSNVTFETTMGNIVCELY WKHAPNTCRNFAELARRGYYNGVKFHRIIQDFMIQTGDPTATGRGGASIYGKEFDDEICE DLRHTGAGILSMANSGPNSNGSQFFFTLAPTQWLDNKHTIFGRVSVGMQVVKRIGLVDTD NDDRPVDDIRIL------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------------KL VVNTIPRIMNCPKVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDQACAGLNNMQLG DKKLIVQRASVGAKGG-QMPVQIQIPGLNMTQVPTEVLCLMNMVTPEELEDEDEYEDILE DVKEECGKYGTVKSLEVPKPIKGIEVPGVGKIYVEFNSVIDCQKAQQALAGRKFSNRVVV TSYYDMDKYHRREF-------------------------PEKAQTKVQSGTVMAVGSGIK TDEGKLIPNDVKVGDQVLLPEFGGTKIVIEDQDYFLFREGDFLGKFERLKTQVPDIKTSL NIVRHLQSKKEDLKMHFQLSDNLYAKAKVPPTEKVCLWLGANVMLEYQLDDAEKLLQKNA AIASLEQVDADLGFLRDQLTTIEVNMARVYNWDVKRRQAAKGMAEEALAKAGLHFDELNK IRVLEPEVAQQTGELKEECKDFLDKLSDFKKIVGTFIDVVDGVAQEVEKEKMKAIGSRNL LKAISKQREAQQQQLMALIAEKKMQLERLRIQHDALLKEEQGQTEFIEQFILQKRKRSRS RDRKSRDRKRSRSRDKKEMSPEERDARTIFCMQLSAKIRPRDLEEFFSSVGKVRDVRLIT DNKTRRSKGIAYVEFGEVESVPLAMGLDGQRLLGVPIIVQASQAEKNRLGGNTGPMRLYV GSLHFNITEDMLRGIFEPFGKIEQVNLVLDLDTGRSKGFGFVTFRNAEDAKKALEQLNGF ELAGRPMKVGHVTERTGEMSMLDSDEMDRAGIDLGATGRLQLMAKLAEGTGFQIPPVAAS ALNMPNPIIAPPIATQCFMLSNMFDPTTTAPNWEVEIQDDVIDECNKHGGVLHIYVDKAS PQGNVYVKCLSIAAAAASVTALHGRYFAGKVITAAYVPLPNYHALFPDASRAVQLVMSSS DEREDEISPTPQQLSVK--RRGAISSEVCTEEDAASYVKKVVPKDYKTMAALSKAISKNV LFAHLDDNERSDIFDAMFPIHRHGGEVIIQQGDEGDNFYVLDQGEVDIYVNNEFVSRIVE GGSFGELALIHGTPRAATVKANTDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLSKVSIL ENLDKWERLTISDSLETVQFEDGQVIVRQGEAGEDFFIITEGSASVFQRKAENEEPVEVG KLGPSDYFGEIALLLDRPRAATVIARGPLKCVKLDRARFERLLGPCSDILKRNITQYNSF VSLSVTQYKGLAKLYRLTYIADHALAYVMTTYNTNLYQQINKKLQEALTSNVPALDTQWI ETTAKKAALKLEKLDTDLKNYKSNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDY CTSAKHVVNMCLNVIKVSVYLQNWSHVISYVNKAEATPHITEGKDSALAVTTKLKCAAGL AELTTSKYKSAARYFLLTNFDHCDFPNLISPNNVATYGALCALASFNRQELQKNVIASSS FKLFLELEPQLRDIIHQFYESKYASCLKLLKEIKDNLMLDLYLAPHVGTLYTQIRNRALC QYFSPYLSADMTKMASAFNTTVAALEEELMQLILDGQINARIDSHNKILYAKDVDQRSAT YAKSLAMGEDFQRRTKALILRSAMLKNQIHVKSPPRDGSTGSEMSIAPASTASMAQRNEM IDKAEDVADQMLRQSKHFLPHVARLCLISTFIEDGLRMWFQWSEQREYINSTWGCGWFLA TLFVLVNLIGQLGTCVMVLIRKHVSIACFVLFGIIALQTIAYSILWDVKFLMRNLALTGG VILLLAEIKAEGRSLFAGLPSLGENTPKTYLQLSGRVLLVLMFLTLLRFDFSFLQMIQNI VGTALILLIAVGYKTKLASLILVANLTILNIYFNAWWNIPTYRPMRDFLKYDFFQTMSVI GGLLLVVAIGPGGYSMDEHKKKW------------------------------------- ------------------------------------------------------------ -------QTVGGLVESLKIITEKNSTRIARYAFDFAKRNGRKKITAVHKANIMKLSDGLF LECCHKVSEEYPDIEFEGMIVDNCSMQLVSRPHQFDVMVLPNLYGNIITSIGAGLIGGAG LVSGVNLGEKYAVFETGTRTTGHEXGGKNVANPTALLLASSDMLRYLGLVPHADVIKNA- -------------------------------SDDFQRFFDKTSRIVERILFEEDNPFVDY TGTDAEKGLAEGEMLKLNRVFFDEHWSKHRTVTCMDWSSQYPELLVASYNNNAESPHEPD GVALVWNIKYKKTTPEFVFHCQSAVMSTCFAKFHPNLIIGGTYSGQIVLWDNRSNKRTPV QRTPLSAAAHTHPVYCVNVVGTQNAHNLISVSTDGKMCSWSLDMLSQPQDSMELQHKQSK VAVTSFSFLANDVNNFVVGSEEGAVYTACRHGSKAGIADMFEGHQGPVTGIDCNTVPGQI EFSPYFLTSSFDWTVKLWNMKENRPLHSFEDNSDYVYDVKWSPVHPALFASVNGMARIDL WNLNTDIEVPTASAVNVALNKCSWHSSGQQIAVGDDHGHIHIYNVGELLATPRNDEWTKF VHTLQEIKNNQADLDDEQ---------------------------ESGFEQLRQNRMEQL KAAQKQKQEWLSLGHGQYEEIADEKEFFEMTKKSANVVCHFYRESTFRCKIVDKHLALLA PKHIETHFVK-------------------------------------------------- ------------------------------------RTLVLNAFGGHDKIKVVEKAKPGA GQVLVTIEACGINFAELMMRQGLYSQALKPPCELGWEGAGVVAELGEGVTTFQVGDKVLC MTNMWTEYAANVHAMPEGMSFEEAAAIQVNYVTAYHMLFEFGNLRKGHKVLIHMAAGGVG VAATQLCRTVPDVVIFGTASAKHDAIKENGVDHPIDYRTQDYVEQVKKISPEGVDIVLDP LSGPDAAKGYSLLKPFGKIIHFGSANTISG------------------------------ ----------------------------------------------------------MS RKQTPSDFLKQIIGRPVVVKLNSGVDYRGVLACLDGYMNIALEQTEEYVNGQLKNKYGDA FIRGNNVLYISTQKRRM----------------LNKNPVEGFSAGLIDDEDIYRWEVLII GPPDTYYEGGFFKAHLTFPQDYPQKPPKMKFMTEIWHPNIDKSGDVCISILHDPGEDKFG YERPEERWLPIHTVETILVSVISMLADPNDESPANLDAAKEWREDKTEFKKKVARCVRKS QETTVRPVNPLVQKTLRDFGNYIGECLPKFVQKVQVTTGDELEVLIHPDGVLPVLTFLRD HTNAQFTNFIDVCGVDMPTRECRFEVVYNLLSLRYNSRIRVKTYTDELTPIDSCSDIYKG AIWFEREIWDMYGVFFSNHPDLRRILTDYGFEGHPFRKDFPLTGYIEMRYDDEVKRVVAE PVEFTQEFRKFEYSTPWEMFPAYNQKVNPFCQVDVPSXIWSCNFCFHRXTFPPQYAAISE QHQPAELIPQFSTIEYTLXKLSCHPPVFLILLDTCMDEEELQAVKESLQMSLSLLPPNAL VGLITFGKMVQVHELGCEGCSKSYVFRGTKDLTAKQIQDMLGIGRGAAQLPANRFLQPLH KCDMALTDLLGELQRDPWPVAQGKRPLRCTGVALSVAIGLLECTYPNTGARLLMFVGGPC TQGPGMVVDDELKHPIRSHHDIEKDNCKYMKKSMKHYESMANRSANNGHIIDIYSCALDQ TGLHEMKYLCNLTGGHMVMGDSFNTSLFKQTFQRVFSKDAKGEFKMAFSSTVEVKTSREL KVQGCIGSCVSNNLGASVSDTELGLGGTSQWKMCGLYPNTTYAFYFEVVNQHTAPIPQGG RGYVQFISQYQHSSGQRRIRVTTLARNWVDASINMQHIAAGYDQEASAVLMARIAVFRAE TDDGPDVLRWLDRMLIRLCQKFGDYSKDSPTSFRFPEQFTLYPQFMFHLRRSQFLQVFNN SPDETSYYRHMLLVEDLTQCLIMIQPILYAYSFNGPPEPVLLDTSSIQADRILLMDTFFQ ILIYLGETISQWRKAKYHELPEYENFKQLLQAPVDDAQEILQTRFPMPRYIDTEAGGSQA RFLLSKVNPSQTHNNMYNDAGGHVLTDDVSLQVFMEHLKKLAVSTSSMSSLTQEEQLKLI SDLEIEMMADMYNRMSSACQKKCVPPRYKDAELNKGEAVCIDRCVAKYMDIHDRIGKKLT SISMQDEETMKKX--TQAPAVIHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYR KKVQLDAEEVQIDILDDYAAIRDNYFRCGEGFLCVFSITEQESFQSTSEFREQILRVKND ENIPFLLVGNKMDLEERRQVTVEEAQARAQEWNVSYVETSAKTRANVDKVFYDLMREIRA QKVAKKKSGRKCVILKLYTGLREVVTEHLTNKVRKDVLESLNNNFLQTLNSAWNDHQTSM VMIRDILMYMDRVYVQQNGVENVYNLGLMIFRDQVVRNPVIRNHLRETLLEMVAKERRGE VVDRGSVKNACHMLMVLGLDSRSVYEEDFERPFLEQSADFYRVESQKFLAENSASVYIKK VEARINEEAERATHYLDKSTEEPMVKVLEEELISKHMKTIVEMENSGVVHMLKNNKTSDL ACMYKLFIRVSNGLQAMYGCISTYLREQGRAMVTEDEGNKNAIVYIQNLLSLKDRFDYFL HESFSDDRRFKQIISSDFEFFINLNTKSPEYLSLFIDDKLKKGVKGMSEQEIENVLDKSM VLFRFLEEKDVFERYYKQHLAKRLLLNRSVSDDSEKNMISKLKTECGCQFTSKLEGMFKD MTVSNSTMEEFKSHITQSTNLHGVDLFVRVLTTGFWPTQSAT-KCNVPNSPRLAFEAFRR FYLGKHSGRQLSLQPQLGSADLNATFYGTARKEDTSKSGPRKHIIQVSTFQMVILMLFNH KDKWTYEEVKTETDVPERDLMRAIQSLALGKMTQRVLTKEPKTKEIEPDHTFMVNDQFTS KLFRVKIQTVAAKGESEPERKETRSKVDEDRKHEIEAALVRIMKARKRMQHNILVAEVTE QLKSRFLPSPVVIKKRIEGLIEREYLARTPEDRKIYTYVADRIDVFPSRMAMAIMKTRLA GAQKGFSLLKKKSDALTSRFRSILKKIIETKMLMGDVMKEASFSLTEAKFAMGDFNHLVL QNVSKAQTKLKSRKDNVAGVSLPVFEHYTDGSDSYMLTGLSRGGQQIDRLKKNYAKAVEL LVELASLQTSFVTLDEVIKTTNRRVNAIEHVIIPRIERTLAYITTELDEREREEFYRLKK VQKKKKEIR--------------PLRVLVTGAAGQIAYSLLYSIAKGDVFGPDRPISLVL LDIEAMMGVLKGVVMELIDCALPLLTEIIPTSDISMAFKDIDVGVLVGAMPRREG----- ------------------------------------------------------------ ------------------------------------------------------------ -IAARKLSSAMSAAKAICDHLKDWFHGTPDGQWVSMGITSDGYGIEKGLIYSMPVKIGQE YTIVQGLSIDDFARSKMDATMKELIEERDAALQTC----GVLMVGPNFRVGKKIGCGNFG ELRLGKNLYNNEHVAIKLEPMKSRAPQLHLEYRFYKQLGQAEGVPQVYYFGPCGKYNALV LELLGPSLEDLFDLCDRRFSLKTVLMVAVQLLHRMEYVHQKHLIYRDVKPENFLIGRQAN KKQHIIYIIDFGLAKEYIDPETHKHIPYREHKSLTGTARYMSIHTHLGKEQSRRDDLEAL GHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPVEVLCENFPDELGTYLRYVRRLD FFETPDYDYLRKLFIDLLARNGWESDWEFDWTGRQMRHGGSVQVLSSANGELGGNGGQSD TPITAPREVEVVSETK--MTTIRPFTCDDMFRFNXVNLDPLTETYGLQFYMQYLAHWPEY FQIAESPQGHVMGYIMGKAEGNSDNWHGHVTALSVAPEYRKLGLAAKLMNTLEEVSERKR CFFVDLFVRVSNQVAVDIYRKLGYTIYRVVLEYYAGEKDEDAYDMRKALSRDVDGKSVIP LQHPVRPEDL---LDSALDLMRRLPPQQIEKNLADLIDLVPGLCEDLLSSVDQPLKIARD KTIGKDYLLCDYNRDGDSYRSPWSNQYEPPLEDGAMPSERLRKLEIEANAAFDQYRDMYF EGGVSSVYLWDLDHGFAGVILIKKAGDGSKKIRGCWDSIHVIEVQEKSSGRSAHYKLTST AMLWLQTNKEGSGTMNLGGSLTRQVESDAPVSDSSPHIANMGRMIEDMENKIRNTLNEIY FGKTKDVVNGLRSTMQLQRENLQNDLAQALRGRS-YEGDFDDVDEPLDEVNDQDQVDILP AGDQVEPQNRITTPYMTKYERARVLGTRALQIAMCAPVMVELEGETDPLQIAMKELK-RK VPIIIRRYLPDGSFEDWGIDDLIITDKRATLRDKAMAPAGDTAFTMGKGLVAGAAILGLG SLCYYGVGLSSEVGAIDRAALWPAVVRERIRDTYLYFGSSLVVTAISRSPVMMNLMMRNS LLAVFGTMAAMIGSGMVCRSLPYTEGAKQVAWMVHSGIVGAVIAPLTLLGGPLLIRAACY TAGVVGGLSTLAVCAPSEKFLNMGGPLAMGLGVVFVSSIGTMFLPPSTALGAGMYSIAMY GGLVLFSMFLLYDTQRIVKKAETHPVYALQPFDPVNESVSIYLDTINIFIRIAMILAGGG NRRRMEIVYVYTKKRAEFGRQCNFTDRAAELHVDIPPDPSLAENFIERNPVDRGTQCVQE MSEHDVNTERFETDSHGVNHTEGGWPKDVNYAEIEQVTRYRKKVEKDEMYVHTINQLGSA MEHCIRQNNAIDIYEEYFVDIDVDAIDEPPSAKTINVFRDPYELKRTATHISWFPDGAKK LAVAYCVLEFQMSSPDTFDSFTWDIENPNKPDMTIKPASPLVCVEYNPKDAHILLGGQYN GQIGFWDTRKGSQPVEITPIEHSHRDPAYKTIWIQSKTGTECFSTSTDGRVLWWDIRKLG EPTESLYLDPTKKQDPTKAQGAMVLEYEPTIPTKFM------------------------ -----HGPVYALQRNPFFVKNFLTVGDWTARIWSEDIKESSIMWTKYHQAYLTDGCWSPT RPAVFFTTKMDGTLDIWDYIFKQNDPILSLQVCDEALHSIRVQEHGRLIATGSHNGTTTL LELSESVYTMQRNEKALVTAMFERETRREKILDARHREMKLKERARTSWEELVQRVTPIA KPLASRKQTKKLYKIIKKALRKGVREVQKFIRKGEKGLVILAGDTNPIDVISHMP----- -----------------------------------------------------MPLENLE DEGLEKNPDLQLAQWKFLLTTDKYKNDRKIKNDLLDAVKEDNMAPFYEQLCSQFDWSVDA SFMQKMKAKNEEKVKELDSAVEDAEKNLGETEVRDFMLKKAEYFSRIGDKESALSQFRKT GEKTVTMGYKLDMIFHQIRLGLFYMDHDLIKRNLEKAQSLIDEGGDWDRRNRLKVYKGAY CMAVRDFKTAANLFLDTVATFTSYELMDYKTFVTYTVFCGMIALDRQDIREKIVKGSEIL EVLHGLPDIKQFLFAFYNCQYADFFKMLAKVEAMMKYDMYLAPHYRFYVREMRIHAYSQL LESYRSLTLVYMAKAFGVTVDFIDQELSRFIAAGRIHCKIDKVGGIVETNRPDSKNWQYQ ETIKKGDILLNRLQKLSRVINI-------------------------------------- ---KNLKKGFSVTVEESAGVLAKFGNEDYEAAGASLSAEDVFKSDIVLKVRAPTPTEIER LRDENTLISFLYPAQNKELIDLMAKRHSTVFAMDCVPRISRAQVFDALSSMANISGYKAV IEAANHFGRFFTGQITAAGKVPPAKVLVIGGGVAGLSAVGTAKNMGAIVRCFDTREAVRE QVQTFGAEFLEVSVKESGEGGGGYAKVMSKEFIEAEMALFAKQCKEVDIIITTALIPGKP APKLITKAMIESMKPGSVVVDLASEAGGNIETTVPGQVTVYHDVTHIGYTDLPSRLSGQS STLYSNNVSKLLLSFGFYVNLEDEVARGSIILNKGELLWPPPKPPPRNYFKETLTDAFMY TTGLSGILGLGMASPNPAFAQMVTTFGLAGIVGYHTVWGVVPALHSPLMSVTNAISGITA VGGMLLMGGGYLPTDTQQTMAAVAAFISAINIGGGFTVTQRMLNMFRRPDDPPEYTKLYL IPALSFLGAYGLATTGNYPDIHQMAYLASALCCIGSLTGLSAQSTCRLGNTLGMIGVSSA IAATLGMIKPSPELFAQMAACVGTGGAIGAVAAKRIEVTDLPQMVALFHSLVGAAAVITC ISNYMAEFSHFATDPAANVIKTSLFLGTFIGGVTLTGSLVAFGKLQGVLKSDPLMLPGRH MMNGALALGNVGAMGYYMMGSELSGLTMLGTTTALSSVMGVTLTMAIGGADMPVVITVLN SYSGWALCAEGFMLDNNVMTIVGALIGSSGAILSYIMCKAMNRSLPNVILGGFGTSSYAG GPAMTITGTHKEVDVMGTVDLLEEAQNIMIVPGYGLCVAKAQYPIAELVTLLKSKGKNVR FGIHPVAGRMPGQLNVLLAEAGVPYDIVHEMEEINDDMPQVDLTLVIGANDTVNSAAEDD PNSIIAGMPVIRVWLSKEVVVMKRTLGVGYAAVDNPIFFKENTSMLLGDAKKTCDSLLTK VK--------GVPPGLEYLASLSSVKISQVLHIEEILLGWERNNVYQIMDQRNQQFLTAK EETDCCTRQFLGNIRPFTINISDMQGGMPVQLTRDLHCQ-GCC----CLQEMDICCPPSY KVATIKEKLCTPRYEIFDTMYTIEGICCYIK--CC-ADVPFKVTRADAGEVVKHWAG-CR EMCGQVNEFTVSYAQNETALNKAILLGSAFLIDFMYFEVKNN----EVQQFLMMEQQKAQ FQSQVHRLVDICWERCIDKPRDKLDSRAETCLSNCVERFVDTSIQITGRFQQMLQRSVMS RSEGLVQRRNVAQEEADLDSKETRLTLMEEILLLGLKDREGYTSFWNDCISSGLRGCILI ELGLRNRVELEKTGMRRRSLLNRKVLCKSDAPTGDVLLDEALKHIKETQPPETVQSWIEY LSGETWNPLKLRYQLRNVRERLAKNLVEKGVCTTEKQNFLLFDMTTHPLVDSTVKAKLVK RVQDAVLSRWVNDPQRMDKRMLSLLYLAHASDVLENAFAPLSDDDYEVAMKRVRELLDLE LEQEAMKDGCNPVMLSVIAAFIKGKKLKSANEENCEVCVKYIGKFIDSLDKVEKAFMKFC KNSKKGNNRLCYYIGGLEESATSIVAELAKPISWGMPSDKICYKLYIKDQQICDLKYEKT VDLATVNLKKLKVKELKNILSDWEEQCRGCTEKSDYIKLIDELMPKYAPEAAIDNILKGF KLNWMNLRDADSGKVLWQSNEDLSQPDVEHEARVPKKILKCRAVSRELNFTSKEPMERFR LEQKVLFRGKCLEEWYFEFGFVIPDSTNTWQSIIEAAPESQMMPANVLNGNVIIETTFYD GDLMVSTSKVRIFYVMPKVVSRSVVCTDTKDKEEYQGEKPLYVYYCLCGQMALILDCPVE KLPLRRRDDARVIDSTKHAHKITSELDETAYLKRRDGIERQYRQKCKTCGLWLFYRHRNQ ITFIVDGALKQSAGVKSDIYSQIAQPKKVMVTKHTKNMGKFSSVTVSTVDEEEEELEAKE IADSYAANAKVIEKQLWRKGLSKRSLIEQAA-EAKRMRPKG-LFD-VRQCARLVTQQQRR GYADMAFTFASPVTVKVKQIDVPSFSGSFGILPDHVPLLAVLKPGVITVHEDDATSKRFF VSSGSVTVNDDSSVQILAEEAIAMENIDA------------------------------- -------CKFFATELKTRLKETGKNREIIETGHGLEKKKRFAYLTSELRLTEALQDPHVC DKILQYNVHAERKGSNRYAKGMSETMSTLHGLRNKGVKVELGIPEEMWDQPSAEVTKMQR SCYKLAEDYEELIEDWYFHHQKDLMNFLCADKFLPDK---FSPTDVTNEADVKAALVAKD KFGRLDVAVNCAGIGIAVVTLNAKKDRVHSLDEFMRVINVNTGGTFNVIRLAAQMMXQNE PNTDGQHGVIVNTASIAAF----------------------------------------- ------------------------------------------------------------ ------------AKSSVGIKYPIIDHQYDAVVVGAGGAGLRAAFGLASKGFKTACVTKLF PTRSHTIAAQGGINAALSSVDDDKWQYHFYDTVKGSDWLGDQNAIHYLCEEAPKAVMELE NYGMPFSRMPDGRIYQRAFGGQSLKYGEGGQAHRACAVADRTGHSMLHTLYGRSLYYDAD YFVEYFALDLLMNQGRCVGVIAVSLEDGNLHRFNATNTVIATGGYGRAYFSCTGAHTCTG DGAGLVARAGLPLEDMEFVQFHPTGIYGAGCLITEGCRGEGGYLVNSEGERFMERYAPSA KDLASRDVVSRAMTMEMREGRGVGELKDHIYLQLSHLPPEQLFSKLPGISETAQVFAAVD VTREPIPVLPTVHYNMGGIPCNYLGQVIEHNGKDVIVPGLYAAGEAGCMSVHGANRLGAN SLLDLVIFGRAIANIIEENHKPGEKVPDMPADAGEMSVDHIETLVNNKGNTPTAELRLKL QKAMHENAAVFRDGPTLQEGVKKVKAIWPEIGIKLSDHGRVWNSDLIEALELQNLVINAM ATVVGAENRKESRGAHAREDYPKRMDEFDYSKPIEGQKRIPIEKHWRKHTMAYVNVNSGD VKLDYRPVIDTVLDDKKVQSIPPKIRQYMTALSQEEIVSNTKTVMQGLDTLKNEHHQILN SLLSSMKTIKKGDTNLVEEKTHILQKALETIDLGLSEAQVMTALATHLQYMEAEKQKLRS QVRRLFQENAWLRDELANTQQKLQSSEQKVATLEEEKKHLEFMSEMKKYDSETSLGFPED DELQQQNAMAQAASGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKSSGHD HPDVATMLNILALVYRDQGKFKEAG-LFHDALGIREKTLGPDHPAVAATLNNLAVLYGKR GKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVERYYKRALEIYV HRLGPDDPNVAKTKNNLASAYLKQGKYQQKIASRYDGEAEAEVLGWINALIGPGMRNVES QLKNGIFLVRLAKAVKAKKMRLKPNTMSAPFKQMENINVFLNYCEAYGVPKTGLFQTVDL YEGRNMAQVLNCIQQLGTECQRNGFNGPTIGARPTEKNIREFTDEQMRAGHLQAGTNKCA SQSMGSARHVADIRADDMDRDGMGIIGLQSGNKGASQAGMSMGSVRHVSDIRADDMDKDG MGVIGLQXGSNKGASQKGMSMGSVRHVSDIRADDMDKDGMGVIGLQAGSNKGASQKGMSM GAVRHVADIRADDMDGGQGIIGLQMGSNKGASQKGMSMGAVRHVADIRADDMGGQGIIGL QMGSNKGASQKGMSMGATRHVADIRADDMAGQGVINLQYGSTAGASQQGMSMGGRRNIMT EAHSFGVIPITCHAWNGDKTQLALPNNHEVHIYKKQWTLEHTLEEHTQRVTGIDWAVQSN RLVTCGADRNAYVWPTLVILRINRAATCVKWSPLENKFAVGSGARLISVCYFEEENDWWV SKHIKKPIRSTVTCIDWHPNNILLAAGSSDFKTRVFSAYIKEVEAKPEATCWGKKMTFNN IMAEFSNGGGWVHDVSFSSSGEKLLWVSHNSSISVVNATSRTEFLPFVTCLWLTENSFVV AGNDCCPVVFSCDGTNISFCAKLDDTKFTAMDHFRSMDKLGSKLGTTHQNTITQVSVYKG TKANCSVFTTTAVDGQLVNWDVKKEVDGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGL GKSTLVNSMFITDLYNADYNGPSHRIKKTVQVDTTQVLLKEGGVQLKLTVVDTPGFGDAV DNSNCWQPVINYVENKYEQYLNAESRVNRNITSDERVHCCLYFIAPTGHGLKPLDIEFMK RLHDKVNIIPLIAKADTLTPDECREFKKTLLNEIARHKIKIYEFDDEEENRHQKKLKDRV PFAVVGSNTVVEAGGRKVRGRIYPWGVVEVENLEHNDFIALRNMLIRTHMQDLKDITNNV HYENFRYSRLAFLAKDPIAQMAEEKKDHVQKLKKMEAEMEQVFEMKVKEKMQKLKDSEVD LQRRMEQMKKSLEQQTKELDERRRAFERERDSWEDIHK---------------------- --------------------------EKNTNKLLDEVSYSEKIYKLNEDMACSVAGITSD ANVLTNELRLIAQRHLLQYQEPMPCEQIVSALCDIKQAYTQFGGKRPFGVSLLYMGWDRH YGFQLYQSDPSGNYGGWKATCIGNNSSAALSMLKQEYKEGKTTVKDALDLAIKVLSKTLD TTKLTSEKVEIATLTREKDVTKLRILPAPELETIIKKYEAEEAKAEAEKKK--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------RCMDLQLFYRDTEQAD TWMTKQEVFLANEDLGDSLDNVEALIKKQEDFEKSLAAQEEKINALDEFATKLIESEHYA ADSVAARRNTLLQRRNALLERSQARHQQLEESYKLQMFERDCDETKIWINEKLKAASDEG YLDPTNLQGKVQKHQNFEAEVSANQGRIENVTQTGEELIEADHYAKDLIRERLDEIQTLW KQLFVQTERKGSKLREASDQQQFNRNVEDFEIWLSEIEGQLMSEDYGKDLTSVQNLQKKH ALLEADVSSRQERIDGIVQACEAFVQSGHFDADNIKSKAEQVLERYQQLSEPIVARREKL NDALRLQQFFRDVEDEEDWIHEKEPIAASTNRGRDLIGVQNLMKKHQALQAELTGHEARI TAVCEQGGEMVTEGHFAADDIQQKIKALQDRWNQLRDKAQQRKQDLEDSLQAQQYFADAN EAESWMREKEPIVGNPDYGKDEDSAEALLKKHEALMSDLEAYRSVIDNLRETAQACKQQE APMVDDIGKECVVALYDYTEKSPREVSMKKGDVLTLLNSSNKDWWKVEVNDRQGFVPAAY VKKIDSSLTASQSNLADEFTVSVREQQVEGQYDNLMELGRQRRQKLEESCKAYQLVREAG ELAQWINDKETVALSEEVGGDLEQVEVIQRKFDDFQKDLKANETRLVELNSIAERLTAMG QTEAAEKIKIQIEDLNTRWAALQQVTVERAQTLGSAHEVQRYHRDAEETKDWIEEKDAAC RLEDYGHDLATVQRLQRKHEGLERDLAALGEKVKELDETANRLMQTHPDQAQSIYDHQKE INESWNALTTMADTRKAKLLDSYDLQRFFSDFRDLKSWIHSMMALVSSDELAKDVTGAEA LLERHQEHRMEIDARSGTFQAFETFGHQLLQNSHYASSEVKEKLQELADARMELESAWIA RRAKLDQCLELQLFNRDCEQAETWMAAREVSLEDSAGGSDTVDALIKKHEDFDRAINSQE EKIAALQTFADQLISNDHYDGPGIEQKRQQVLDRWKNLKTALLDNRSKLGEAQSLQQFSR DADEMEIWISEKLQMAMEESYKDPSNIQSKHQKHQAFEAELAANADRIQTVIKMGQKLID QHQCAGSEDAVQKRIDKLVEEWEYLTSKSSEKSEKLKEANRQRMYTAAVKDLEFWLGEVE HMLETEDYGKDLATVQNLVKKHQLLDADINAHEERISDLNEQADVFIDSGVLDTESIKEK KRSINERYERVKTLGVHRGTRLNEAHTLYQFFRDIDDEEAWIKEKKLLVGSDDYGRDLTG VQNLRKKHKRIEAEISSHEPTIEAVQQTGEKLTAESDLFTEEISTRLQQLTTNWEELKQM TNTRGHKLDESLAYQQFAAGIEEEQSWITEKQHLLSGDDFGDTLATVQGLLKKHDAFETD FQVHQDRFQVIKTDGEKLIEEGNHNAAAIEQRCGLLQEKLNALRKAADNRKARLVDNSAF LQFIWKTDVVESWIADKQTQVSSEEYGRDLSAVQILITKEETFDAGLQAFEKEGIQTITT LKEQLVSSNHAQTPAIEKRYQDVITRWQKLLSDSDARKQRLLLLQEQYRQVEDLYLAFAK KASTFNSWYENAEEDLTDPVRCNSIEEIKSLREAHDQFKASLSAAEVDFNQLSQLDKQIL SFNVGDNPYTWFTMQALEDTWRSLQKIIKERDEELAREQQRQEENDVMRKQFAQAANAFH GWLTETRTTMMEGNGTLEEQLEATKVKAVEIRSQKSQLKYIEDLSAVMEERLILDNRYTE HSMVGLAQQWDQLNQLAMRMQHNLEQQIDACNKSGVSEDSLREFSMMFKHFDKDKSGRLD HQELKSCLRALGYDLPMVEEGQTDPEYEAILDAVDPNRDGFVTLQEYMAFMISRETENVQ SAQDVEAAFRALTSNERPYIQAQELYSNLTRQQADYCISRMKPYIDPKGRTVPDAYDYID FTHELFINAIQCYQCDSNEDKSCPAHKPFDLYLNALVDCNSFEADIPGIFCMKITQQSPG WYGWKKITRRCGRRATGGVAWGCRWQFEENGVWKEVCYCEDKDGCNTSS-IDAEDGDNPQ LVSLYVNDIYDYMRHLEAEDINGRMRGILVDWLVQVHLRFHLLQETLFLSIAIIDRFLQD EVSRSKLQLVGVTAMLIASKYEEMYAPEIADFVYITDNAYTKADIRRMEVTILRQLNFQL GRPLPLHFLRRNSKAGEVDANKHTLAKYLMELTIVDYDMVHMRPSEIAAAALCLSIALLG WSDTLVHYSKYEETHLKDIMRHMAHLATRKLTAIKTKYQSSKFMRISTIPELRSQQIIDL AARGRNRGRRQNNPSPGPDNDLERVFIWDLDETIIIFHSLLTGSYAQRYGKDPPGSVSLG LRMEEMIFNMADTHLFFNDLEECDQVHIDDVSSDDNGQDLSNYNFATDGFHAAATNNLCL ATGVRGGVDWMRKLAFRYRRIKEIYSSYRNNVGGLLGPQKRELWLQLRSEIEALTDNWLT LALKSLSIINSRSTCVNVLVTTTQLVPALAKVLLYGLGSVFNIENVYSATKIGKESCFER IVSRFGRKCTYVVVGDGRDEEAAAKQMNWPFWRITNHSDLAALHHALDLGYL-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------MTKKVVGAKIACLDFGLMKAKMKMG VQILLETPEKLDGIRQREMDITKERIKKILAVGANVILTTGGIDDLCLKYFVEAGAMAIR RCKKADLRRIAKATGGQLIVTMANLEGEETFEASLLGQADEVVQERICDDELVFIKGPKA RSAASIILRGANDYMVDEMERSVHDALCVVKRVLESKLVVPGGGAVEAALSIYLENFATS LSSREQLAIAEYARSLLTIPKQLAVNAAKDSTDLVAKLRAYHNTSQMKLEHKELKWVGLD LYEGVVRDNKKAGVFEPAVSKIKSLKFATEAAITILRIDDMIKLQPEQ------------ ---GNENARLLASKTILNNFLVEGKDLTVEYNIYNVGGSAAISVQLADASFPETDFEVVR GNTNVKWARIAPGSNVSHIVVLRPLKSGYFNFTSADISYVASEQEPQMAYTSSPGEGGIM NYKDYDRKFSPHVLDWAAFGVMTLPSLGIPFLLWYSSKSKYEQIKTK------------- ----------------------------RQVLVDFCNHLTQLPDDVAEDVAQFTLEKVQS RVISFEEQVALIRQHLASIFERKQMWKEAANILVGIPLETAQKQYTSDYKLETYLKIARL YLEDEDPVQAEAYINRASLLQSDSSNEELQIYYKVCYARVLDFRRKFIEAAQRYNELSYK TIVAEQERMTALRNAVICTILASAGQQRSRMLATLFKDERCQQLPAYGILEKMYLDRIIR SGELQEFAQMLQVHQKATMADGSTILAHAVIEHNLLSASKLYNNISFEELGSLLEIPPSK AEKIASRMISEGRMNGCIDQIDCTVHFEAREALPNWDKQIQSLCFQANNIIEKIAAHVPD WMAKTMDETMT------------------------------------------------- ------------------LDQHTHATNTVNSQLTKVDDTISXFXLHDNKYIRNFQGHXKK VVTLHMSPIDDTFLSGXLDKSMRLWDLRSPNCQGLMHLPGRPVAAFDPEGLIFAAGINSE SLKLYDLRSFDKGPFTTFKLQQDKDCDWTGLKFSPDGKLILVSTNGQVIRLIDAFQGTSL QTFMGHANHKGIALEASFSPDSQFVFTGSTDGKIHCWNTDTGAKVAILNGDHTGPVQCIQ FNPKYMMLSTACSNMAFWLPQVDEEYLIVETKGEKNNVGLIQLNRPKALNALCAGLMGEL GQVLDDLESDPNIGCIVLTGSGKAFAAGADIKEMEKKEFSDVYSSNFLNNWTRLADTRKP VIAAVNGFALGGGCEVAMMCDIIYASEQAQFGQPEILLGTIPGAGGTQRLTAAIGKSKTM ELVLTGNKMSAQDAEKAGLVSKVFPRDQLVDEAIKTAEKIAGLSSIIVAMAKEAVSASFE TTLREGLHFEKRLFHQTFATKDQKEGMNAFVEKREAKFTD >Riftia_pachyptila MSERKAVIKNADMTEDMQQDAVDCATQAMEKYNIEKDIAAYVKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAVLLFKSG--TQLREFQTSVTQRDIDQAAKYIGAGAATV GVAGSGAGIGSVFGSLVIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLILFAFM SHYKDSGKAPDVTIHRIRITLTSRNVKSLEKVCADLIRGAKDKNLKVKGPVRMPTKLLRI TTRKTPCGEGSKTWDRYQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADMDQVM QFIEPAKQFSKDSIRLVKRCTKPDRKEFQKIAMATAIGFAIMGFI--------------- ------------------------------------------------------------ -------------VQKRFSFPEGTVELYAEKVATRGLCAIAQAESLRYKLIGGLAVRRAC YGVLKFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGEPIGDYIDSAVRHVLLRQ GVLGIRVKIMLPWDPSGKIGPKRPLPDHVSIVEPKNRPEPTPSHTDEQ----SKRGRGGS SGGKFRISLGLPVGAVINCADNTGGKNLFVISVYGIKGRLNRMPAAGSGDMIIATVKKGK PELRKKVMPAVIIRQRKHIRRKDGVFIFFEDNAGVIVNNKGEMKGSAITGPVAKECAELW PRVASNASSIRKGKTQKVVLGPNVMEGENVFGVAHIFASFNDTFVHVTDLSGKETIVRVT GGMKVKADRDEASPYAAMLAAQDVAERCKALKISALHIKLRATGGNRTKTPGPGAQSALR ALARAGMKIGRIEFVTP-----------------MGKPRGIRTARKMRTHRREQRWHDKD YKKGHLGTRWKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP RDGCLNYIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKQKKERPRSDGT TTVRTRKFLTNRLLCRKQMVVDVFHTGRATVPKTEVREKLAQMYKTTSDVIFCFGFRTQF GGGRTTGFALIYDSLDFAKKLEPKYRLQRHGSRKQRKDRKNRMKKVRGTKKSKVRSMPRV PLVCRKTYTTPRRPFEKERLDQELKIIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDE KDTRRLFEGNALLRRLVRIGVLDESKMKLDYVLGLAVEDFLERRLQTQVFKMGLAKSIHH ARVLIRQRHIRVRKQVVNVPSVI------------LRSPHGCGRPGRVKRKNMRKGAGGD AEMGLTISNLFNRLFGKRQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRDRVVEAQDELNKMLQEDELRD AVLLVFANKQDLPNAMTAAEITEKLGLSQLRGRNWYIQATCATQGQGLYEGLDWLSQEL- ---MPLAKDLLHPSLEDEKRSCKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRRKQHMVRMNVLADALKSICNAERRGKRQVLLRPCSKV IVRFLTVMMKHGYIGEFEIIDDHRSGKIVVNLTGRLNKCGVISPRFDVALRDLESWTNRL LPSRQFGFLVLTTS-----------------------VGRMHVPGKGISQSALPYRRSIA TWLKLSSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKKKGLAPS IPEDLYHLIKKAVAIRKHLERNRKDMDSKFRLILVESR-HRLARYYKTRRVLPPNWKYES STASALVA---------------------------------------------------- ------------------------------------------------------------ EDSTRIGRAGTVRRQAVDVSPLRRVNQAVWLLCMGAREAAFRNIKSIAECLADELINAAK GSSNSHAIKKKDELERVAKSNR-------------------------------------- -------------------LRGHGHFVSDVVMSSDGQFALSGSWDSTLRLWDLNTAQTTR RFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIEDGHTEWVSCVRFSPNT QNPIIVSCGWDKLVKVWNLTNCKLKTNHYGHTGYLNCVTVSPDGSLCASGGKDGQAMLWD LNEGKHLYTLDGGSIINALTFSPNRYWLCAATGPSIKIWDLEGKIVVDELRQEVISTSAE PPQCISLAWSADGQTLFAGYTDNLIRVWQVSM--------------------ALTMQFVC HQFLDYHDPTIEDVYQHQARIDGEPAQLEILDTAGAPTFTAMREQYMRAGEGFVVCYSVI ARRSFDEALEYKKLIDRVRSADTTPIVLVANKCDLEHLRKVST----------------- ---------------------MSEEKKEGSDHINLKVTGQDGSVVHFKIKKNTPLRKLMS AYCERTGVKMGSMRFRFDGQPINETDTPSQLEMEDGDSIDVFQQQTGGMATLPMNPKPFL NGLTGKPVMVKLKWGMEYKGYLVSVDGYMNLQLANTEEFIDGALCGNLGEVLIRCNNVLY IRGVEEEDEEGEMKDMSDAEGDDVPS--ISTGGMDINAALQEVLKNALIHDGLARGLHEC AKALDKRQAHLCVLANNCDEPMYVKLVEALCAEHGINLIKVDDNKKLGEWAGLCKIDKEG KARKVVGCGCVVVKDYGKESQALDVVNEFFKSK--------------------------- ------------------------RQVELALWDTAGQEDFDRLRPLSYPDVHVVLMCFAI NNPDSLENITGSWTPEIVHYCPKVPIILVGNKGDLRYDRDALELMSMQNLKPVSKEQAET VAKNISAHAYMECSAKTRDGVREIFETAARLTLKRTRQSNGPMDDFQSSEETAFVVDEVS NIIKESIEAAIGGNAYQHNKVNQWTSNVVEQCLNQLTKLAKPFKYIVTCVIMQKNGAGLH TASSCFWDNSTDGSCTVRWENKTMYCIVSVFGLAI------------------------- ------------------------------------------------------------ ---------SQRRILPKPTRKSRRKNKQKRPRSRTLTAVHDAILEDVCFPAEIVGKRIRV KLDGSRLIKVHLDKSQQTNIEHKLDTFRAVYKKLTGKDVAFEFPEFVL------------ ------------------------------------------------------------ ------------------RTRFKAFVAIGDHNGHVGLGVKCSKEVATAIRGAIVLAKLSV IPVRRGYWGNKIGKPHTVPCKVTGKCGSVLVRLIPAPRGTGIVSAPVPKKLLTMAGIEDC YTSATGQTATLGNFAKATYAAISNTYAYLTPDLWRETVFTKSPYQEFTDHLAK------- --------------------------------------------------------AVHF VEPTTDVCVISARPYGQRAVLKFASYTGSTPVAGRFTPGTFTNQIQAAFREPRMLIVTDP RMDHQPVTEASYVNIPVIALCNTDSPARYVDIAIPCNNKNNHSIGLMWWMLAREVLRLRG TILREVPWDVMTDLFFYRDPEE-------------------------------------- ----------NKLVSSSRRTNRRRHFQAPSHIRRKIMSSPLSKDLRQKHKVRSIPIRKDD EVQIVRGHYKGQQVGKVVQVYRKKFVIHIERIQREKANGASVNVGIHPSKVVIVKLKMDR DRKSILERKS----------------------STVRQRKTTSGGASAAGMWRFYTEDSPG IKVGPVPVLVMSLLFIAVVFMLHIWGKYAR-REGRKKKQVTHEVVTREYTVNIHKRIHGI GFKKRAPRSIKALRQFXEKMMGTPDVRIDTRQEQTQW----------------------- -------------------------------------------KKIGSGSFGDIYLGINI ANGEEVAVKLEQTKARHPQLLYESKLYNILRGGVGIPHIRWYGERDYNVLVMELLGPSLE DLFNFCSRRFTMKTVLMMADQMIGRIEYVHNKNFIHRDVKPDNFLMGIGRHCNKLFLIDF GLAKKYRDNRTHAHIPYREDXNLTGTARYASINAHLGIEXSRRDDMESLGYVLMYFNRGS LPWQGLQXATKKQKYEXISEKKMSTPVEVL--------AMYLNYCRGLRFEEAPDYMYLR QLFRILFRTLNHQYDYVFDWTILKQKAA--MNAEKLKQRIGGKGTARKKKEVIHRTATTD D----------------------------------------------------------- ------------------------------DDDDVPDLVENFDEASKGEMVRYSLDPENA TKSAKARGSHLRVHFKNTRETAHNIRHMHLRRAVRYLKNVMAEKECVPFRRYNGGVGRCA QAKHWGTTQGRWPKKSAEFLLQLLKNAESNAEFKGLDTDHLVIEHIQVNRAPKMRRRTYR AQWKDQPNMSSPCH---------------------------------------------- ------------------------------------KKEEIKKMISDIDKEGTGQIDFND FLTMMTLKMSEKDSKEEILKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQEADRD GDGEINEPEFLRIMKKTSLY---------------------------------------- -------------------VDTGNFAWGSEAQARKTRIIDVIYNASNNELVRTKTLVKNC IVQIDAGPFRQWYEAHYATPLGRKKGTKLTEVEEAVLSKRSKKTQKKYDERKKDSKVDAA LEDQFITGRVLACVASRPGQCGR---YILEGRELEFYLRKVKAKKGK-SLVIPEKFQHIL RVMNTNIDGRRKVPFAMTAIKGVGRRYSTVVCRKADVDPNKRAGEMSDEEVEKLLTIMSN PRQYKIPDWFLNRQKDVKDGKYTQVMSNSLDNKLREDLTRLQKIRNHRGLRHFWGLR--- ---------------------------------------------------------RKA RKAMSKLGLKQIQGVTRVTIRKSKNILFVINRPDVYKSPASDTYIVFGEAKIEDLSQQAQ MAAAEKFKAEEEIDETGIEAKDIELVMSQA-----------------------MGRVRTK TVKKAARVIIEKYYTRLTLDFHTNKRVCEEIAIIPSKKLRNKIAGFVTHLMKRIQRGPVR ASPSNCEEEERERXDNYVPEQSAIEE--PTTKDMLKLLDMHNIAGLQVTQPIASTMKWEY KEEHSFDKRRTEGEKIRKKYPDRVPVIVEKAPKARVGDLDKKKYLVPSDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGALYQEHHEEDFLLVYSY-------MRELRILKL CLNICVGESGDRLTRAAKVLEQLTGQXPCFTKSRYTVRSFGTEETRRFAVHCYV------ ----------------------------------------------------------YT VSKRKKRRGRIGPQHRIKKDDAMKWFQQKYDGVILPGK---------------------- ------------------IFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGIS PIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMVITVGQSIVYVMTGMYGDPAD IGAGVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVN TGRGTEFEGAVIALFHLLATRQDKVRGLREAFYRQNLPNLMNLMATIFVFAIVIYFQGFR VDLPIKSARYRGQQSSYPIKLFYTSNIPIILQSALVSNLYVISQMLATKFGGNFIINLLG VWADVASGGPARSYPVGGLCYYLSPPETLSHVLEDPVHAVLYIVFMLGSCAFFSKTWIEV SGSSAKDVAKQLKDQQMVMRGHREKSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIG SGTGILLAVTIIYQYFEIFVKEQGEMGGMSTLLFQTERAFQKQGNVFLNKKKLLIPRFYR NVGLGFKTPREAVEGTYVDKKCPFTGNVSIRGRVLSGVVIKMKMQRTIVIRRDYLHYVRK YNRFEKRHKNMSVHLSPCFRDVNLGDVAIVGECRPLSE---------------------- XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------- ------------------------------------------------------------ --------------YCGKKANLQIGNILPVGQMPEGTIICCLEEKMGDRGRLARASGNYA TVVSQNPDTKRTRVKLPSGTKKMIPSANRAMVGIVAGGGRIDKPLLKAGRAYHKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHL----------------------------------- -AKRTKKVGITGKYGTRYGASLRKLVKKMEITQHGRYTCSFCGKEAMKRRAAGIWSCKGC RKVVAGGAYVYCTTAAATTRSAVRRLREMKEMGRRPARCYRYCKNKPYPKSRFCRGVPDS KIRIFDLGRKKAGVDEFSLCVHLVSDEYEQLSSEALEAGRICANKYLXKHCGKDAFHMRI RPHPFHICRINKMLSCAGADRLQTGVRGAFGKPQGTVARVHIGQPIISVRARENSKDSVI EALRRAKFKFPGRQKIHVSSKWGFTKWEKDEFGTMRTDGILIPDGVNVQYKPPHGPLKAW MARQKVVKVLGRTGSQGQCTQVRVEFIDDTSRYIIRNVKGPVREGDVLTLLESEREARRL RMTKGTSSFGKRHNKTHTLCRRCGSRSYHIQKKTCSRCGYPAARMRKYNWSEKAKRRRTQ GVGRMRHMKIVLRR----------------MLDDRASVKELDQWIEQLSQCKQLSENQVK TLCEKAKEILAKESNVQDVKCPVTVCGDVHGQYHDLMELFQIGGRSPDTNYLFMGDYVDR GYYSVETVSLMVSLKVRYKERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDNQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHSNALTLVTRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRC GNQAAIMELDDALKYSFLQFDPAPRRGEPHVTRRTPDYFLMGAYKYMQELWRKKQSDAMR FLLRVRCWQYRQLSAIHRAPRPTRPEKARRLGYRAKQGFVVYRVRVRRGGRKRPVPKGAT YGKPTNQGVNQLKFQRSLQSVAEERVGRKCGALRVMSSYWVAQDSTYKYFEIVMVDPHH- --------------------VHGRTKGTTRVVGVREGYAFNGTIGGSWRASWKRNNTLQL RRKRGIATGRLSEERKAWRKDHPFGFVARPTKNIDGTLNLMNWECAIPGKKSTPWEGGLY KLRMLFKDDYPSSPPXCKFEPPLFHPNVYPSGTVCLSLLDEDKDWRPAVTIKQILLGIQE LLNEPNVKDPAQAEAYTIYCQNRGEYERRVREQALRFRDPSM-KSSRMLHHINYRMRCTL QDGRIFIGTFKAFDKHMNLILGDCDEFRKVKPKNAKQREEKRALGLVLLRGENLVSMTIE GPPQPEEGVARVPLPGAAAGPGMGRAAGRGIQSVVGLQGPVRGVGGPSQQIMQP------ ------------------------------------------------------------ --WDTAGQEKFGGLRDGYYIQGQCAIIMFDVTARITYKNVPNWHRDLVRVCENIPIVLCG NKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPF-----------------XPA LEPPEVQMDPDMVAKYEQELVIAQQTVLPDEDDDL------------------------- ------------------------------------------------------------ -----------------------------------------------------------I KEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ KFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSARLESGSGGDSEVQRTMLELLNQLD GFEPKQNIKVVMATNRIDILDSALLRPGRIDRKIEF------------------------ -------------------------GMYALRERRVHVTQEDLELAVAKVMQKDSEKNMSI KKLWK------------------------------------------------------- ------------------------------------------------------------ -----------------------------RQYNGMIDVYKKTMKSDGIAGLYRGFVISCV GIIVYRGCYFGFYDTLKPLVLGEDAGLFISFMLGYVVTISAGLVSYPIDTIRRRMMMTSG QAVKYKGSLDCTMQIIKHEGVVSLFRGAGANILRGVAGAGVLSGFDKFKELYVAWRLMTD NSDLDRQIEQLRNCEVIKESEVKSLCAKVREILVEESNVQRVDSPVTVCGDIHGQFFDLK ELFKVGGDIPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRLTLIRGNHESRQITQV YGFYDECLRKYGSITVWRYCTEIFDYLSLSAVIDGKIFCVHGGLSPSIQTLDQIRAIDRK QEVPHDGPMCDLLWSDPEDTQGWGVSPRGAGYLFGSDVVAQFNASNSIDLICRAHQLVME GYKWHFNDTVLTVWSAPNYCYRCGNVAAILELDEHLQRDFTVFEAAPQEQRGKPQADYFL VRLPPEVNRILYIKNLPYKITAEEMYDIFGKYGAIRQIRVGTTQDTRGTAFVVYEDIFDA KNACDHLSGFNVCNRYLVVLYYQPNKAYKKLDQQKKQEDLDHMKQKYGLSTPEKKMSIGV PIKVLHEAEGHIVTCETNTGVVYRGKLVEAEDNMNCQMVNITVTYRDGRVAELENVYIRG SKIRFMILPDMLKNAPMFKKISAGRGKSAILRAAARGRGRAGG--SRGGMQNEGGEYVDM YIPRKCSASNRIIQAKDHASIQINIAEVDPTTGRMTGQNKTYAICGAIRRMGESDDCIIG LAKRDGIIAK-------------------------------------------------- -----LTYDEVKKIVNQRLIKVDGKVRTDKCYPAGFMDVISIERTGEDFRLIFDVKGRFA VHEITPEEAKYKLCKVKKLQVGPKGVPFLTTHDARTIRYPDPLIKVNDTVQV---KDDEY DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTA GQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADNNIVIMLVGNKSDL RHLRAVPTDEAKAFAEKNNLSFIETSALDSTNVETAFQNILTEIYKIVSQKQFPDSPEGN NVETIIVAPTDNTGGRGKRPCCMTARYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVAVR GKDLVVLGVERKAVAKLQEDRTVRKIALLDDHVALAFAGLTADARILISRARVECQSHKL TVEDPVTLEYITRYIAQLKQRYTQSNGRRPFGLSTLIIGFDGTAQLYQTDPSGTYHAWKA NAIGRSAKTVREFLEKYYQDDLVSERETIKLALKALLEVVQSGSKNMEVAIMRRNQPLKM MTVDELEEYIKEIEKEKEEEAEKKKQKGNGPGGDKKDDKDKKRKYEPPVPTRVGKKKKKL KGPDAANKLPQVTPHTRCRLKLLKLERIKDYLLMEEEFIKNQERLKPQEEKQEEERSKVD DLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDSLEPGCSVLLNHKVHAVV GVLSDDTDPMVTVMKLEKAPQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIKSPK GVILYGAPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPS IIFIDEIDAVGTKRYDSNSGGEREIQRTMLELLNQLDGFDSKGDVKVIMATNRIDTLDPA LIRPGRIDRKIEF----------------------------------------------- -----------------DFRKAKENVLYRKNEGTPEG---KRKSYTPFTGTNVMDFTLAR ADDLVNWARKSSLWPMTFGLACCAIEMMHFAAPRYDMDRFGVVFRASPRQSDCMIIAGTL TNKMAPALRKVYDQMPDPRWVLSMGSCANGGGYYHYTYTVVRGVNRIVPVDIYIPGCPPS AEALLYGILQLQRKIKRMKSIQMWYRKTDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYA NNSNYKNDTMIRKEAYVHKSVMEEMKRMIVDSEVMQEDDNLWPPPDRVGRQELEIVIGDE HIAFNTSKIGSLVDVNQSKDPEGLRTFYYLVQDLKCLVFSLIGLHFKIKPIMVAQKKSKK AIESINSRLGLVVKSGKYVLGYKQTLKTLRQGKAKLIIIANNTPPLRKSEIEYYAMLAKT GVHHYNGNNIELGTACGKYFRVTTMSITDPGDSDIIRSMPSAMTEYKLVVVGAGGVGKSA LTIQLIQNHFVEEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGF LCVFAVNNTKSFEDINQYREQIKRVKDAEEVPMVLVGNKVDLPSRSVEMKQGKMLAESFI IPYVETSAKTRQGVDDAFYTLVREIRKY-------------------------------- ---------------DMLNYFAIVENESKARVRFNLMERMLQPCGPPPERPEDMKIELCS FSGYKIYPGHGKKVVKADGRPFMFLSAKCEKSHAMKRNPRKINWTVLYRRKHKKGQQEEV SKKRTRRTTKFQRAITGATLSDIMAKRNQKPEVRKAQRXQAIRAAKEKQRVKEQARPHVG GK---------------------------------------------------------- -----------------------------------------GCIVDANLSVLNLVIVKKG EKDIPGVTDTTIPRRLGPKRASKIRKLFNLSKEDDVRQYVVRRPV-PRTKAPKIQRLVTP LVLQRKRHRLALKKHRAERKREDAADYAKLLAQRMKEGRRK------------KVKARDL RGKKKDDLEKQLGELKTELSQLRVAKVTGGVASKLSKIHIVRKSIARVLTVINQTQKENL RKFYKPKDLRAKKTRAMRRALTKYEVSLE--------------------------VTEKV YMDITIGGEEVGRIVIGLFGDTVPRTVKNFATLADGS-GYQGSSFHRVIKEFMIQGGDFS AGDGTGSQTIYFDDENFVLNHYGAGWVSMANAGKDTNGSQFFITTVQTSWLDGAHVVFGR VIEGMDVVRKIEATETGDDHPVKTVLIAKCGVIAVTEPFQVEKSSA--KKKKVLLRFVLD CSQPVEDGIMNVGDFEKFLHEKVKVNGKMNNFKSKLIVQSDIAFXKRYLKYLTKKYMKKN NLRDWLRVVATTKDTYELRYFQINNEEDEE----TKEEKGDEEAKYGSCEGPDAMYVKLV SSDGHEFIVKREHALTSGTIKAMLSGPGQFAENEMNEINFREIPSHVLQKVCMYFTYKVR YTNSSTEIPEFPIAPEIALELLMA------TREITLSEIKQHTTAEDCWVAVDGMVYDLS DYIDIHPGGNESIEAEAGTEATKAYDFVGHSAYANKMMAQYQIGVLVEEKK--------- --------------MSYMLQHLHNGWQVDQAILSEEDRVVIIRFGHDWDPTCMVMDETLY KVAEKVKHFAVIYLVDITEVPDFNKMYELYDPCTTMFFYRNKHIMIDLGTGNNNKINWAM EDGQEFIDIVETIFRGARKGRGLVVSPKDYSTKYRYKKLQRQLEFLEVQEEYIKDEQKNL KKEYLHAQEEVKRIQSVPLVIGQFLEAIDQHTGIVGSTTGSNYYVRILSTIDRELLKPSA SVALHKHSNALVDVLPPEADSSITMLQADEKPDMTYADIGGMDIQKQEVREAVELPLTHF ELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVR DVFRLAKENAPAII--------------------------------------------VV MATNRADTLDPALLRPGRLDRKIEFPMPDRRQKRLIFSTITAKMNLSEDV---------- --------------------------------------------------SHPPVTLDSI KDRVLFVLSHYDKVDPEKLVVDSHFMNDLGLDSLDQVEVIMAMEDEFGFEIPDSDAEKLM RPADIIQYVADKEDI---------------------------------------GIYSYG FEKPSAIQQRAIRPVVKGRDVIAQAQSGTGKTATFSIAILQCLDTQFRETQALILSPTRE LAGQIQKVILALGDYMSVQCHSCIGGTSIGEDIRKLDYGQHVVSGTPGRVFDMIRRRNLR TRSIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLLSATLPHDILEMTSKFMTDPI RILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKM REANFTVSSMHGDMLQKEREAIMKEFRSGASRVLITTDVWARGIDVQQVSLVINYDLPNN RELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI------ ------------------------------------------------------------ ------------------------PLVDDPYMMGKIACANVLSDLYALGVTECDNMLMLL ALALKLSDKERDVVVPLMIRGFRDLAEEAGTSVNGGQTVKNPWMTIGGVATTVCQSNEFI MPDNAVVGDVLVMTKPLGTQVAVSAYQWLDQPDRWNRIKLVVSEDDVRKAYQRAMFSMAR LNRVAARLMHKYNAHGATDITGFGILGHANNLARIQKNEVGFVIHNLPVIAKMAAVSKAC GNMFGLLQGHSAETSGGLLIALPREQAAAFCKDIEKQEGYQAWIIGIVEKGNRTARIIDK PRVIEVPAKEKE------------------------------------------------ -----------VYSGERESNGKYTFAAHTDGLYKYCFSNKMSTMTPKVVMFSMNIGEKPK ASHNKLEEMINELSVGLMGVKHEQEYMEVRERIHRAVNDNTNSRVVMWSFFEALVLVAMT LGQIYYLKRFFEVRRVVMAATLQPYLSAVRHTLTAAMCLENFSSQVVERHNKPEVEVRSS KELLLTPVVISRNEKEKVLIEGSINSLRISIAVKQADEIEKILCHKFMRFMMMRAENFVV LRRKAVPEYDISFLITNVHTEQMYKHKLVDFIIHFMEEIDKEISEMKLAVNSRARISAEE FLKQF-----------------------------------------------------IC TLQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTMPNTFKTLDSWRDEFLIQASPRDPEN FPFVVIGNKIDLENRAVSTKRAQQWCHSKGDIPYFETSAKEAINVEQAFQMVAKDALAQE KDTEMFNEFPDQIKLT----------TAAFDVRFPNANQTKNCWQNYVDYHRCHKIESYE PCEYFKRVYRSMCPNEWIGKWDEQIESGTFAGKIMPDFLGKDQRKTKDDSDEDKPIQVLD EGDIALLKTYGAGMYSRSIKQIEDDIQDVMKKVNELTGIKESDTGLAPPALWDLTADKHT LHSEQPLQVARCTKIIDADTDNPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNK YQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVEMPLLHPERFVNLGI EPPKGVLLYGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMART KKACIIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDT LDPALIRPGRLDRKVEFNLPDLEGRTQIFKIHARSMSVEKDVRYELLARLCPNTTGAEVR SVCTEAGMFAIRARRKMATEKDFLEAVNKVVKAYAKFSATPRYMTYN------------- ---------------------------------------------------------ITI DIALWKFETNKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQT REHALLAYTLGVKQMIIGVNKMDNTEPPYSETRFEEIKKEVAQYIKKVGYNPDTVAFVPI SGWHGDNMLKMAWFKGWKVLSGNTLMDALDNVQQPSRPTDKPLRLPLQDVYKIGGIGTVP VGRVETGIMKPGMVVTFAPANLTTEVKSVEMHHTALTEALPGDNVGFNIKNVSVKDVRRG FVCGDSKNDPPLETDEFLAQVIILNHPGTIQAGYAPVLDCHTAHIACKFKELKEKIDRRS GKVLEANPQSVKSGDAAMVEMIPQKAMCVEKFSEYAPLGRFAVRDMRQTVAVGVIKNVKK REGGSGKVTKAAQKA----LRQEAEQLKNQIREARKAAADISLTQAAANVEPVGRIQMRT RRTLRGHLAKIYAMHWGTDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCSYAP SGSYVACGGLDNICSIYSLKTREGSVRVSRELPGHTGYLSCCRFLDDNQIVTSSGDMTCA LWDIETGQQTTSFTGHTGDVMSLSLSPDMRLFVSGACDASAKLWDIRDGMCKQTFSGHES DINAITVFPNGYAFATGSDDATCRLFDLRADQEIGMYSHDNIICGITSVAFSKSGRLLLG GYDDFNCNIWDTLKQDRAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKIWNMSYAYLF KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES FRSITRSYYRGAAGALLVYDITRRDTFNHLTSWLEDARQHASSNMAIMLIGNKSDLEARR DVKREEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYQKIQDGVFDINNEANGIKI GPQHSPTSGTSSPGSNQGGGMTRGRTELGDITVHNIKQLKRLNQVVFPVTYNEKFYQDVL EXGELAKLAYFNDIVVGAVCCREDRSQGQRRLYIMTLGCLXPYRRLHIGTVMLKHVLKIC EEDGNFDNVFLHVQINNDSAIKFYEKFGFEIVERKTSYYKRIEPADAFVLQKTFR-MPKQ IMEIKDFLLTARRKDAKSVKIKKNVKFKVRCSRYLYTLVIQDVEKAEKLKQSLPPGLGVK ELK--RLHRDTLAEAIAAVLQKKRKFTETVELQISLKNYDPQKDKRFSGTVKLRHIPRPN MKVCVLGNQQHCDEAKANEVSFMDVDALKKLNKNKKLVKKLAKKYDAFLASDSLIKQTP- ------------------------------------------------------------ ----VNFLVSLLRKTRQNVRALYIKSTMGPAQRIYMADTDKLNIDSIIARLLEVRGSRPG KNVQLTENEIRGLCLKSREIFLSQPIMLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYEECKRRYN IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKETMG--------------------------------------GYEFFAKRQLVT LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKXFPYGGLNGRGPTGPP------- -----------------------------KKVRNGHIKRITDNDIQSLVLEIIGTNVSTT YITCPAESKKTLGIKLPFLVMIIKNMKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPF ICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDEL PAEFKLYLPIQKE--------------------------------TTVQGIRPDYDLKKI VKACKKEFACNGTVVEHPEYGEVIQLQGDQRQHISQFLKKVGLEDQLKVHGFSALFNFQS LLTVVLLLICTCAYLRSIAPRMLDKNKEGLLGIFWKCARIGERKSPYVALSCIAMAVSIL FWSSGRITAALSRQLPRAFTKRNALAAGFVANRKFSATSEVSSILEERIMGSPEANLEET GQVLSIGDGIARVYGLNNIQAEEMVEFSSGLKGMALNLEADNVGIVVFGNDKLIKEGDIV KRTGAIVDVPVGEDLLGRVVDALGNVIDGKGALTGKSRARVGVKAPGIIPRISVKEPMQT GIKAVDSLVPIGRGQRELIIGDRQTGKTAIAIDTIINQKRFNEGQDEKAKLYCIYVAIGQ KRSTVAQMVKRLTEADAMKYTIIVSATASDAAPLQYLAPYSGCAMGEYFRDNGKHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDDFGGGSLTALPVIE TQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQIRAMKQVAG SMKLELAQYREVAAFAQFGSDLDAATQQLLNRGVRLTELLKQGQYVPMAVEDQVAIIYAG VRGHLDTMDPMLITKFEEEFIAHVRSSHQDVLDTIRKETQISDDTEAKLKKIVVDFLAGF MEVFYSIPFTVLECPNIKLKRPSWVATPSPMVVFALVLLSYFFVTAGVIYDVIVEPPSIG STTDEKGVSKPVAFMQHRVNGQFIMEGLASSFLFVMGGMGFVLLDQTNKPTTPKLNRILL LSVAFVCIAVSFFMCRVFMRMKLPMPKVRRSRKPPPDGWELIEPTLDELDAKMREVETDP HEGKRKVEGLWPIFRVHHQKSRYIFDLFYKRRAISRELYEYC------------------ ------------------------------------------------------------ ----------------------------------GVRDYRTTRTDVILKYTPDEARNLKA YGELPESAKINDDGED-IIF------LVRFLMKLSHETVTIELKNGTQVHGTITGVDVSM NTHLKAVKMTLKNRDPVQVDALSIRGNNIRYYILPDSLPLDTLLVDDAPRAKAKKTTLAK PKSEMTAEELSAREQEEFNTGPLSVLTQSVKNNTQVLINCRNNKKLLGRVKAFDRHCNMV LENVKEMWTEVPKMGKGKKKSKPVNKDRYISKMFLRGDSVILVLRNPLPILIDARGHLLG RLSALVAKTILQGQRVVVVRCEEINISGNFYRNKLKYLSYLRKRMNTNPVRGPYHFRAPS KIFFKAVRGMIPHKLPRGKDALTRLKVFEGVPAPYDKQKRMVVPSALK------------ -SRLSHEIGWKYQGVIATMEAKRKVKSKRFYEQKKTEMKLREQAKKIAPYQKIIESFG-- GDVEKGKKIFVQRCSQCHNAEAGAKHKQGPNLFGMFGRKTGQAPGFSFTDANRNKGIVWS AETLDIYLENPKKYIPGTKMIFAGLKKKADRQNLIAFLESA--IYVERTLAIFKPDVVTQ ELEEIILSSGFTILQKKRLVMTPEQTSDFYAEHYGKLFFPSLVAYMSSGPLIAMVLAKSN AITYWRELIGPTNTVKARQTHPDSLRAIYGTDETRNGFHGSDSLYSSDREIRFFFSNSIV EPIPRGQAARDYVAKTINPTLLAGLTALCKAKPINPVRWLADWLMENNPNKPDV-MFEAR LVQGSLLKKVLEAVKDLLNEATWDCNSTGISLQAMDSSHVSLVSLMLRCDGFDTYRCDRN LSMGINLTSMSKIMKCAANEDAITIKAGDNADTVTFMFESPNGEKVSDYEMKLMDLDTEH LGIPETDYSCVIKLPAGEFQRICRDLSQIGESVVICCTKEGVKFSASGDLGTGNIKLAQT SNVDKEEEAL-----------------------------------SDVPLVVEYKIGEMG YIRYYLAPKIEDGEDA-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------RFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIA ELGIYPAVDPLDSTSRILDPYIVGQEHYDIARGVQKILQDYKSLQDIIAILGMDELSQED KLVVSRARKIQRFLSQPFQVAEVFTGTEGKLVPLKDTIRGFNMILKGELDHLPEVAFYMV GGIEEVVARAEKLAE-----PKKNRVAIYENLFKEGVMVAKKDFHAPKHPELDIPNLQVI KALQSLKSRGYVTEQFAWRHYYWYLTNGGIQYLRDFLHLPPEIVPSTLKRQTGGEDRSQY RRG--------------MGKAESKIKPKDLEELRKMVDFSTEEIEQWYKSFHKDVPSGYI NIDEFKKIYGNFFPYGDASAFAEHVFRTFDKDGNNSIDFQEFICALSVTSRGKLEDKLKW AFDMYDLDSDGTISKVEMLEIVKAIYKMVQ----MPVDESTPEKRVEKIFHQMDTNNDGK LSLEEFVEGAKSDPSIVRLLQCNMMSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNL TGLNEQVPHYRQALDMILDLEPDDELEDNPNQSDFXSRPPKMLYGLIHARYIMXNRGIAQ MIEKWQQGXFGYCPRVYCENQPMLPIGLSDVPGESMVKLYCPKCQDVYTPKSSRHHHTDG AYFGTGFPHMLFMVHAEYRPKRPPNQFIPRLYGFKIHPLAYELQYQAASNFKTGYGN--- LNDKK--------------DRNRTVTLSQFMIVYKRGDIVDIKGNGAQQKGMPHKSYHGR TGRVYNVTPHAVGVIVNKRVKGRIIAKRINVRIEHVKHSNCRLDFLRRVEENEKKKKEAK ATVNCKRIPQQPREGHFVSTRYNKPVVLQQIPYEFIAAGRTFWKQVSPADPSYEWRDMTD KAANTIFILEICKGLGITLSMLFKEPATLNYPFEKGPLSPRFRGEHCLRRYPSGEERCIA CKLCEAICPAQAITIEAEPRADGSRRTTRYDIDMTKCIFCGFCQEACPVDAIVEGPNFEY STETHEELLYNKEKLLDNGDRWEPEIAANLQADYLYR----------------------- ------------------------------------------------LAQFWVTAFVNH PQISAILXEEEEECLHHLNAVEVEEFEDIKSGYRIKLHFNENQYFNNSILIKEFHLAASQ STPVKWKDGMNLVTKARKRRHGPARTFFQWFLDNSDPSADDIAEVIKDDMWPNPLQYFLA PDIQMDENDDDD------------------------------------------------ -------------------------ENVKFLLKHKIALKRSEAVTREVMRKVADDKKMAK QEKDERILWKKNEVADYEATTFSIFYNNALFLLFIVLMSFYILRSLSPVVNYTASMVTAG GLLALFSTSSK--------FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQT VCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFARAKTWVKELQRQ ASPSIVIALAGNKA--------EAQAYAEENSLLFMETSAKTAMNVNDIFLAIAKKLPKT DLGVDLNQDN-------------------FYFKIGACRHGDRCSRLHNKPTFSQTILLQN LYINPQNTAQIHVSDVEMQSHYDGFFEEVFVELESKYGEIEEMNVCDNLGDHLVGNVYVK FHREESAEKAVADLNNRWFNARPVHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKP ISHELRRELYGRKGRKRSRSPPTRRSRSRSRRDNRRHGRDRKR--MFLTRSEYDRGVNTF SPEGRLFQVEYAIEAIKLGSTAIGIQTNEGVVLAVEKRVTSPLIEPSSIEKIMEVDTHIG CAMSGLIADSRTMIDRARVEAQNHWFTYNERMSVESITQAVSNLALQFGDDDADPGAMSR PFGVALLFAGIDPKGPQLYHMDPSGTFIQYDAKAIGSGSEGAQQALQDTYHKSMTLKEAC KESLVILKQVMEEKLNATNVEMATVTPQRMFKMFTKEEIEGIIKDIAQKTWEMSNNVQTI GTLDEIYHYDKKQHQDILTAKPWDKDPHYFKCIKISALALLKMVMHARSGGNLEVMGLLL GKVDGNTMIVMDSFALPVEGTETRVNAQAQAYEYMAAYTESAKQVGRLENAIGWYHSHPG YGCWLSGIDVSTQMLNQQFQEPFVAIVIDPVRTISAGKVNIGAFRTYPKGYKPPDEGPSE YQSXPLNKIEDFGVHCKSYYSLDVSYFKSVLDCKLLSSLWNKYWVNTLSSSSLITNAEYT TCQVFDLAEKLEQSDGXVGRGGFMEKSLND-LAKATKDGCKNTIEVIHGLMSQVIKDKLF NQTGGLPRRIIKETQRLQAEPVPGIVAIPDDSNARYFHVDVAGPKESPYEGGVFKLELFL PEEYPMSAPKVRFMTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPD DPLANDVAEQWKVNEAQAIEIARQWTKRYA-ADNEILDYEEEDDHEAKDVKGTYVSIHSS GFRDFLLKPELLRSIVDCGFEHPSEVQHECIPQGILAMDVICQAKSGMGKTAVFVLATLQ QLEHVDGQVSVLVLCHTRELAFQISKEYERFSKYMNNVKIAVFFGGMPIKKDETVLKTNC PHIVVGTPGRILALSKTLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMF SATLSKEIRPICKKFMQDRKRILV------------------------------------ -------------------------------------------------------ATNLF GRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGSSSLVVLTEKES--PPTYADLG KAARDLFNKGYNYGFYKIEAKTKTINGVEFTSNGSSNHDSGKFAGSLETKYKWKDYGLTF LEKWNTDNTLGTEITIEDQLVKGLKLSFDTHFAPQTGKKSGKIKTSYKQEYVNLNCDVDF DFAGPTIHGAAVLGYTGWLAGYQMSFDKSKLARSNFAVGYSKDDFTLHTSVNDGTEFFGS VFQKVNKDLETGVQLNWTAGSNATRFGIAAKYTPDCCSTFRAKVNNSSQIGLSYQQKVRD GVTMTLSTLVEGKNFNQGGHKIGLGLDFEADSVREKSLQDYRKKLLEHKELEARLKDMRE QLKELTKKYDKSENDLKALQSVGQIVGEVLKQLTEDKFIVKATNGPRYVVGCRRQIDKSK LKPGTRVALDMTTLTIMRYLPREVDPLVYNMSSEDPGDITYAQIGGLGDQIRELREVIEL PLMNPELFQRVGITPPKGCLLFGPPGTGKTLLARAVASQLEANFLKVVSSAIVDKYIGES ARLIREMFGYARDHQPCIIFMDEIDAIRRFSEGTSADREIQRTLMELLNQMDGFDALGQV KMIMATNRPDTLDPALLRPGRLDRKIEIPLTNEQARLDILKIHSASIAK-GEIDWEAVVK LSDDFNGADLRNVCTEAGMFAIRNERDYVIEEDFMKAVRKVSDNKKLESKLDYKPVMPET ISTAVSKFCNEYMTSTSKKLKMIDAYLLYVMLTGIVQFAYFCFVGSFPFNSFLSGFISCI GSFVLAVCLRLQVNPQNKPEFLGIGPERAFADFIFAHIILHLVVINFIGSLSAPAQLLPL ELVDKCIGSRIHIVMKNDKEIVGTLLGFDDFVNMVLEDVVEYESTPEGRRITKLEQILLN GNNITMLVPGGDGPD----------------------TGLVGAPACGDVMKLQIRVDENG KIIDAKFKTFGCGSAIASSSLATEWVKGKTLDEASEIKNTDIAGELSLPPVKLHCSMLAE DAIKAALHDYKVKREMLVLVLGDLHIPHRCNTVPPKFKKLLVPGKIQHILCTGNLCSKES FDYLKTLASDVHIVKGDFDENLNYPEQKVVTVGQFRIGLCHGHQVVPWGDTESLAMLQRQ LDVDILITGHTHKFEAFEHENKFYINPGSATGAYNALNSKIIPSFVLLDIQQSTVVAYVY QLMGDEVKVERIEYKKMVKFLKSGKVVLVLNGRFAGRKAVIVKNYDDGTTDKQYSHALVA GIERYPRKVTKRMAKKRIKQKSKIKAFVRVYNFNHLMPTRYSIVNLDK--INKEAFKDPA RRQKAKREAKMKFEERYKSGKNRWFFQKLRF----------------------------- ---------------------LKDKPFFGGLVKYMSSGPVVPMVWEGGVVKTGRVMLGET NPANSAPGTIPGEI---------------------------------------------- ----------------------------------RTSVHFKRPRTYKAPREPKYPRKSTQ RRPRLDKYKVIRFPLTTESAMKKIEDNNTLVFIVDKMANKPQIKVAVKQLYDIDVSKVNT LNRPDGEKKAYVRLAPHYDALDVANKIGIIMPSKQRMRIASEKHSKNVQNRGNVPKTLKS GEDEYPVGPWLIGLFLFVVCGSAVFQIIQSIMMLKITGWTAVATWRWVANDDNCGICRMP FDGCCPDCKLPGDDCPLVWGNCSHCFHMHCIVKWLNSQQVQQLCPMCRQD---------- ----------------------KQKLIEEVHAVVTVRDAKHTNFVEFRNFKIVYRRYAGL YFCICVDISDNNLVYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYSVVDEMFLAGEIRE TSQTKVLKQLLMLSSLEGDTIFGKIIRKEIKTDFIWEDDQCVAFRDLNPQAPTHFLVIPK KPIVQLSSDEQLLGHLLVVARKVATQTDGYRLAINDGRHGGQSVYHLHVHVLGGRQLGWP P----------------------------------------------------------- LKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSMDRDRIGISKQELVSMLEEDELKKSV LVVFANKQDIEGAMTVTEVANSLGLSIIKNRKYQIFKTSAIKGEGLDEAMEWLANTLQNT K----------------------IVVGHYKVEIFDKAQNQYLPTVAGLGMHVEVKDPDEK VVLSRTYAADGRFTFTSHVSGEHVICLHSNSTAWFGGGQLRVHLDIQVGEHAVDYQQVAA KDKLTELQLRIRQLLDQVEMITKEQNYQRYREERFRQTSESTNQRVLWWAIAQTVILLGT GFWQMRHLKSFFEAKKLVMFYHVSLEHEIMLHPRYFGPXLLNIVKQKLFTEVEGTCTGKY GFVIAVTTIDNIGAGMIQPSRGFVLYPVKYKAIVFRPFKGDXLDAVVTQVNKVXLHRLFG PLSCFI------------------------------------------------------ ----------RLYVKAVFTGFKRGLRNQHENTALLKIEGVASKKETDFYLGK-------- ---------------------------NSGCVRAKFRKNLPPKAMGRRIRIMMYMAKKTY DLLFKLLLIGDSGVGKTCLLFRFSDDAFNTTFISTIGIDFKIKTVELGGKKIKLQIWDTA GQERFHTITTSYYRGAMGIMLVYDITSGKTFDNITKWIRNIDEHANEDVVKMILGNKCDM EDKRQVPKEKGETIAREHAIPFLETSAKTNVNVEKAFMDLAQAILNK------------- -----------------------------------------HSEKVQMRKTIKMHEERRT KKKEADVVPDGAVPTYLLDREGQSRAKVLSNMIKQKRKEKAGKWEVPLPKVRGVGEAEVF KVVRTGKSKRKAWKRMVTKVTYVGEGFTRKPPKFERFIRPMALRFRKAHVTHPELKATFC LPMIGVKKNPSSPMYTSLGVITKGTIIEVNISELGLVTQGGKVIWGKYAQVTNHPENDGC INAVLLVMSARPLITVYDEKGLPTSSNVTLPAVFRAPIRPDIVNFVHFEMKKNGRQPYAV SEKAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKVWRRWHRH INIQQKRYAICSAMAS-------------------------------------------- -----------------------------------IYNQDNGITRAFRNIPGITLLSVDR LNLLKIAPGGHVGRFCIWTESAFKKLDGLYGTWRKPSSEKNGFNLPMPKMTNTDLARLLK SDEIQKAIRPPQKTRHRHILKRNPLKNLRIMMRLNPYAGVQKKTAKRKKQKQTRIDQRRG IATMDTTGRGRPRK----SGEQELATKTLQIQSKRFYLDVKQNRRGRFIKIAEVGSGGKK SRLLLAMSTAAEFRDHLNDFSEHYASLGPPSPDSLPEDGKLKSEVMVKDNRRYYLDLKEN QRGRFLRVSPRSQQRSQIAIPAQGMIEFRDALTDLLDEFGTDDHEGQGELPEPRSMRVEN KMFYFDVGQNRRGVFMRVSETNFRTAITIPERSWARFRDILSDFVDKXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXX----------------------------------- ------------------------------------------------------------ ---MVECFNAKYVSLHVRKSNRAALHLYASTLKFTKSDIEPKYYADGEDAYAMRRDLTEF GEKAMSHTILLVQPGRKPEGRTYSDYESVNECLEGVCKIYEEYLKRMNPNSPSITYDISQ LFDFIDQLADLTCLVYEKTSSKYLPHNKAWIKEKIYILLRKQAGKMAEEG-EKKEQETKK VIHTYPLVRHSDMPDEMKTEAMELCVTACEKFSSNNETAAKMIKDTMDKKFGASWHVVVG EGFGFEMTHEIKNMMYMFFGGTTGILLWKCS----------------------------- --------------------------------------------------------VSSV VLVVESPYGRRRLHFKYSTRFXGEFKHRFYTNWCRSKKKAFTKYAKKWEDDMGKKEIEKD LAKMKKYCKVIQIVCYSQIKLLKKRQKKAHVMEIRLNGGTIAQKIDWAREQLEKQIPVGS VFAQDEMIDVIGVTKGKGFKGVTSRWHPKKLPRKTHKGLRKVACIGAWHPSRVSFSIARA GQKGYHHRTEINKKIYRIGEGVHAKDGKVIKNNASTEYDITQKTITPMGGFPHYGEVNND FIMIRGCCVGPKKRVLTLRKSLLV--------------IDTTSKFGHGRFQTHEEKQNFM GPLKKD------------------------------------------------------ ---------YDRLRPLSYPQTDVFLICFSLISPASFENVRAKWFPEVSHHCPNTPIILVG TKLDLREDKETVEKLKEKRLSPITYPQGLAMAKEIGAVKYLECSALTQKGLKTVFDEAIR AVLCPKPKPKKPPKCSLL----------------------------------KKKKKKPF SLTELEESLPSGEPSLPMKKKKQNSDIEYTYDELLNRVFDIMRERNPEMVAGEKRRFIMK PPQVLRVGTKKTSFSNFADICKMLHRQPKHLLAFLLAELGTSGSIDGNNQLIIKGRFQQK QIENVLRRYIKEYVTCHTCRSPDTILQKDTRLYFLQCETCGSRCSVASIKSGFQAVTGKR AAIRART----------------------------------------------------- -------------------------------------HYDSERGEFGGFGSVSGKIEIEI KINHEGEVNRARYMPQNPCVIATKTPSSDVLVFDYTKHPSKPDPSGECQPELRLKGHQKE GYGLSWNPNLNGNLLSASDDHTICLWDINATPKEGRVIDAQTIFTGHTSVVEDVAWHLLH ESLFGSIADDQKLMIWDTRNNNTSKPSHTVEAHTAEVNCLSFNPYSEFILATGSADKTVA LWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHIWDLSKIGEEQSADDA EDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEEPDTPAA ELEMPAPSRARVYVDVNNHRPREYWDYESHVVEWGQQDDYQIVRKLGRGKYSEVFEAINI TNNEKCVIKILKPVKKKKIKREIKILENLRNGTNVIALVAIVKDPVSRTPALIFEHVNNT DFKQLYQTLTDYDIRYYLFELLKALDYCHSMGIMHRDVKPHNVMIDHDNKKLRLIDWGLA EFYHPGQEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPFFHGHDNY DQLVRIAKVLGTEELYEYIDKYQIDLDPRFNDILGRHSRKRWERFVHSENQHLVSPEALD FLDKLLRYDHQERLTAAEAMDHPYFYPIVKE----------------------------- -------------------------------------------DGIHPRPRKVMQLLRLR QINNGTFLRLNKATIHMLRIAEPYITWGMPNLKSVRSLVYKRGFGKLDGRRIPLTDNAFI EEKLGKCGIICMEDLIHEIYTVGPHFKEANNF-----LXTPLGGWRKKNNHYVHSGDYGD REEKINELLRKMMQFLLLFSRQGKLRLQKWYGAQPTKQKKKITRELITTILTRKPKMCSF LEWKDMKVVYK-------------------------------------VCELDIIFNFEK AYFMLDELVLGGEVQETSKKNVLKAIAAQDLLQEEEPRGILEELGL-MSKAHPPELKKYM DKKLTLKLNGGRAVTGYLRGFDPFMNLVIDETVEESKTGEKNNIGMVVVRGNSIVLLESL DRI--------------------------------------------------------- -----DTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFQQTSKWIDDVRTERGGDVIIM LVGNKTDLSDKRQVSTEDGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMEQTEQ KKMIEVKLKDTPTEPQQ--------------------------------KRVTMVRGLIR EVAGFAPYEKRITELLKVGKDKRALKVAKRKLGTHKRAKKKREEMANVLRKMRSAXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------------- ------------------------------------------------------------ -------------VHRVLKVHERENGTVKFLTKGDNNSVDDRGLYAPGQLWLQKKDIVGR AKGFVPYVGIVTILMNDYPKFKYTVLALLGVFVLLHRE---------------------- ---CLSARFVCMIHTQKTISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYR GAHGIIVVYDVTDQESFNNIKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEY ADQLGIPFL--------------------------------------------------- ------------------------------------------------------------ -------------DPQDQAEEDGANVDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDPENL KPADLVGVNKDSYLILETLPQEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELIEAVVLP MTHKERFETLGIQPPKGVLLYGPPGTGKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGA KLVRDAFALAKEKAPAIIFIDELDAIGT-----------------------LXGFMPNSD IKVIAATNRVDVLDPALLRSGRLDRKIEFPTPTEEARARILQIHSRKMNVNPDVNFEELA RCTDDFNGAQCKAVCVEAGMIALRREATELCHEDYMDAIMEVQAKKKANLNYY-KDAADQ NFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRQDKRVKLQIWD TAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDNAQVVLVGNKC DLEDERVVSTERGKQLADQLGLEFFETSAKENVNVKAVFERLVDIICDKMSESLDSDPTQ TKRLTENPNPQNAGCQCLRTHKMAITRNYLAQPRLTYKTVSGVNGPLVILDDVKFPKFAE IVQLTLQDGTRRSGQVLEVSGSKAVVQVFEGTSGIDAKHTTCEFTGDILRVPVSEDMLGR VFNGSGKPVDKGPSVCAEDFLDIQGQPINPWSRIYPEEMIQTGISAIDGMNSIARGQKIP IFSAAGLPHNEIAAQICRQAGLVKLPSKSVQDSHSDNFAIVFAAMGVNMETARFFKQDFE ENGSMENVSLFLNLANDPTIERIITPRIALTMAEFLAYQCEKHVLVILTDMSSYAEALRE VSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQLPILTMPNDDITHPIPDLT GYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRDDHSDVSNQLYACYAIG KDVQAMKAVVGEEALSADDLLYLEFLQKFEKNFISQGAYENRTIFETLDVGWQLLRIFPK EMLKRIPAAKIAKYYPR--GEPSFIGIKFCQECNNMLYPKEDKEDRILLYACRNCDYKQK ADNACIYVNKIAHEVDALTQIIGDVIADPSLPRTEDHPCPKCGHREAVFFQSQSRRQEEG MQLYYVCTQPSCTHRWTE-----------------------------MMMRRVYGPQKPL RGARIAGCLHMTVQTAVLIETLLELGAEVQWSSCNIFSTQDHAAAAIAKRGVAVYAWKGM TDEEYIWCIEQSLVFPCGEPLNMILDDGGDLTNLVHTKYQQYLPAISGISEETTTGVHNL YKLMAKGLLKAPAFNVNDSVTKSKFDNLYGCRESLVDGIKRATDIMLAGKVAVVAGYGDV GKGCATALRAFGARVLVTEVDPINALQASMEGYEVTTMEAACKEARIFVTATGCRDIIRG EHFSQMLEDSIVCNIGHFDIEIDVKWLDDNAAVKDTIKPQVDRYTLKDGRHIILLAEGRL VNLGCAMGHPSFVMSNSFTNQVLAQIELWSKKGTYKIGVHMLPKKLDEEVAAAHLEHLGV KMTSLTVVQSEYLGIPPQGPYKPDHYRY-------------------------------- ---------HAYDQHLNMILGDVEETVTMVEIDEETYEEIYKSTRRNIPMLFVRGDGVIL VSPPMRTMSSSNVENFSPQIIRHLAKEMSELQKNPPEGVKVFINDEDITDVQASIEGPAG TPYAGGFFRVKLILSKNFPSEPPKGFFLTKIFHPNVAQNGEICVNTLKRDWKAEFGIKHI LLTIKCLLIVPNPESALNEEAGKLLLEQYDDYSTRAQMFTEIHAKP-------------- ------------------------------------------------------------ -------------------------------------------FGFYEIFKMFYSGLLGE ENTYLWRTSLYLVASASAEFFADLFLCPMEAVKVRIQTSPGWAGTLREGMPKLFGEEGMM GFYKGIVPLWGRQIPYTMMKFACFERTVEALYMYVVPKPRGECTKSEQLMVTFVAGYIAG IFCAIVSHPADTIVSKLNKDPGASFMGIAKDLGFAAMWKGLFPRIIMIGTLTALQWFIYD SVKVYYRLPRPPPPSMPESLRLKLEHWKNERILDIIMAPLIPATVIYLFDMALTLLCLHI NWGLEGVVTDYVHISIAAFAALCMFNYTDVGLGQAIRSLYS--NEQQEEDASELTFPKEF ENAETLLISEVQRKQQNESAEEEQELPEVFVKTLNYTSRFTKFKNKETIGAVRSLLMQKK LHKFELASLANLCPESAEEAKALIPSLEGRFEDDEMQQILDDIQTRRSFQY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------EIEVRPGIVSKDTEGKLTCKPIFSKIV SLFAEQNDLQYGVPGGLIGVGTKIDPTLCRADRLVGQVLGAVGTLPEIFIELEISYFLLR RLLGVRTEGDKKGAKVQKLSKNEILMVNIGSLSSGGRVLAVKADLAKIGLTSPVCTEVRE KIALSRRVEKHWRLIGWGEIRRGVNVKP-------------------------------- --------------LADSQAMIRSRMLRENGRFIPRQSFXDEEGILNNKETGYXVKNPMT DPSVMMDMMKGNLTNVLPMIVIGGWINWAFSGFLTTKVPFPLTLRFKPMLQRGIELGSLD ASWVSSAXWYFLNVFGLRSMYNLILGQDNAADQTRMMQDQMSGAAMAMSPDPSKAFKAEW EELEITDHSWALEEVEEEIM---------------------------------------- --------------------------------------------------VVFLIDSFDR ERFVEAKAELDSLLTDEQISNAPVLILGNKIDIPGAASEDEIRHIFGLHGQTTGKGTVAR SELRPMELFMCSVLKRQGYGEGFRWLAQYINVIRRNRPGTLATEWSNWPNESFEEMDSTL AVQQFIQQAIRNDFTNIDDILSPPDGQDEGVWKYEHLRQFCMELNGLAVKLQAECNPETC SQMTATEQWIFLCAAHKTPKECPAIDYTRHTLDGAACLLNSNKYFPSRVSIKESSVAKLG SVCRRVYRIFSHAFFHHRPLFDEYENETALCRRFTTFVTKYNLMSKDNLIVPILDEQMPN IKLQSSDGEIFDVDVEIAKQSVTIKTMLEDEEDDEEAVPLPNVNAAILKKVIQWCTYHKD XPPPPEDDENKEKRTDDISSWDAEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMI KGKTPEEIRKTFNIKNDFTPAEEEQVRKENEWCE-------------------------- --------------------------------LKGRVFEVSLADLQDDEVTFRKFRLIAE EVQGRHVLTNFHGMNLTTDKLRSMVKKWQTLIEANIDIKTTDGYLLRLFCIGFTNKRQNQ IKKTFYAQTEQVRNIRRKMVDIMAREVSSNDLKELVNKLIPDS---------RGVYPLRD VHIRKVKILKKPKFDLGKLMELHGEGSSSTVGEDGEKLDRPDNYEPPVLEEV-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------KSVELEDVKFHQCVRLSRFEN DRTISFIPPDGEFELMSYRLNTHVKPLIWVESVIEKHMHSRVEYMIKAKSQFKRRSTANN VEIIIPVPMDADSPKFKTTTGSCKYAPDMCAVIWTIKSFPGGKEYLMRAHFGLPSVENEE TEGRPPIHVKFEIPYFTVSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRTQMGILEK IGEIEKEIARTQKNKATEYHLGLLKAKLAKYRAQLLEPTGKAGAKGEGFDVMKSGDARVA LIGFPSVGKSTLLNVLTETHSECASYEFTTLTCIPGVIQYNGANIQLLDLPGIIERAAAG KGRGRQVIAVARTADVVIMMLDALKGDKQRELLEMELEAVGIRLNKRRPNIYYKIKKGGG LSFNSTLPLTYCSEKLVQMILHEYKIFNAEVLFREDCTADEFIDVIVGNRVYMNCLYVYN KIDQISIEEVDRIAHQPHSVVVSCNMRLNLDYLLEQLWECLALVRVYTKKRGEHPDFEGG LILR-------------------------------------------------------Q AKHHPDLIFCRKQPGVAIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGSYQGRCVIC GGPGVSDAYYCKECTIMEKDRDGCPKIVNLGSAKTDLFYERKKYGLQE-PNLPPISGEKL SGKSDSRKVWVPANRYTPLKDNWMKIFTPIVEHLHLQIRFNVKTRNVEIKTCKETTDIGA LQKAADFVKAFTVGFDVDDALALMRLDELYLESFDITDVKPLKGDHLARAIGRIAGKGGK TKFTIENVTKTRVVLADTKVHILGSFQNIKIARTSICSLILGSPP-KVYGNMRAVAARMS ER---------------------------------DLNCLYYDLGLPHRDQTNDQVTIDS AEAIMKHNVGIKCATITPDEARVEEFKLKKMWLSPNGTIRNILGGTVFREPIICKTIPRL VPGWTQSIVVGRHAFGDQYKATDFVVPGPGKLEMVFTPANGDAQKMEVYDFKNGGGVGMG MYNTDESITGFAHACFQYAIKKKWPLYMSTKNTILKRYDGRFKDIFEDVYEGNYKAEFEK LGIWYEHRLIDDMVAQVLKSNGGFVWGTKNYDGDVQSDIIAQGYGSLGLMTSVLMCPDGK TIEAEAAHGTVTRHYREHQKGNPTSTNPIASIFAWTRGLEHRGNLDNNKDLVRYAQVMEQ ACIETVDAGKITKDLAGCIYGIKNVKPDQYLNTEDFLDAINETF-MGKLLSKIFGNKEMR ILMLGLDAAGKTTVLYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWR HYYAGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMKPHEI QEKLGLTRIRDRNWYVQPACATAGDGLYEGLTWLTSNAKSFGDLKSEAGISTLNGYLSDK SYIEGYQPSQGDAVVFAALSGPSEKFPNARRWYNHISSYDSQRNSFPGSKKSLDSYGGSA VAGDDDDDD------------------YTARKATAEVAKVTLCWTVKPWDDETDMKELER CVRTVACDGLLWG----------------------------------------------- -----KVQEVREVTRMERIGAHSHIRGLGLDDALEARQVSQGMXGQAAARRAAGIILEVI KEGKIAGRAVLIAGQPGTGKTAIAMGMAQALGADTPFTSIAGSEIFSLEMGKTEALTQAF RKSIGVRIKEETEIIEGEVVEIQIDRPASGTGAKVGKLTLKTTEMETIYDLGQKMIESLT KEKVQAGDVVTIDKATGKITKLGRSFTRARDYDAMAAQTKFVQCPEGELQKRKEVVHTVS LHEIDVINSRTQGFLALFSGDTGEIKTEVREQIQPRTGSGREEGKXEFVPGXVQLDEVHI LVVVCFHF----------------------------------------------SLSRAE EKEIKQILQIRCEEEDVEMTEDALMVLTRIGMETSLRYAIQLITTASLVCRKRKGTETSV EDIKRVYSLFLDESRSTQFLKEYQQEFMFHE----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------QRTWLI HWSLFVFFNHPKGRDLIIEMFLGQPPYLNAIQTMSPHILRYLTTAVITNKHVLKELVNII QQESYTYRDPITEFLECLYVNFDFDGAQQKLRDCEKVLVNDFFLVACIDDFIENARLLIF ETFIRIHQCISISMLAEKLNMPPEDAERWIVDLIRHSPLDAKIDSKLGHVVMGTNAKSPY QQVIEKTKDLAYKSQMLVMAVEKKLRQK-MGVQVETLTQGDGCTYPKDGQTVVVHYTGMF EDGKKFDSSRDRNQVFKFRIGKGEVIKGWDEGIKQMSVGQRAKITCTSDYAYGKTGHPGI IPPNSTLVFDVELLSLQMPKYYCDYCDTYLTHDSPSVRKTHCNGRKHKENVRVYYQKWLE EQVQQLVDDTTAAFKAGASKSS----GGAAIPPPTNM-GPMPGP-MGMMGPGPGGPMPP- -----------------ETLSLERDVQRAIALLDQLQRSGNFEKLAALQQVLQSDFCAAV REVYEHVYETVDITGSPEVRASATAKATVAAFAASEGHAHPRVVELPKTEEGLGFNVMGG KEQNSPIYISRIIPGGVADRLGGLKRGDQLLSVN-VNVDGEPHEKAVDLLKAAQGTVKLV VRYTPKVLEEMEARFDRQRNARRRQ----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------DYDKPEHIVDPDAKKPEDWDDEMDGEWEPPMIDNPEYKGEWKPKQIDNPAY KGVWVHPEIDNPDYKADDELYKYSDIGAIGFDLWQVKSGTIFDNVLITDDEKYAEEFAEE TWGKTKDGEEKMKNKQDEEEKKKREEEDKKSGDKDDAEDEEEEEMDTSVPEPSLYIVKAI LILDNDGNRLISKYYDDTYPTPKEQKSLFTKTHRANAEIIMLEGLTCVYRSNVDLFFYVI GSAQENELILVNVLNCFYDAVSQILRKNVEKRALMENMDGIFLAIDEVCDNGIILESDSS AISQKVSFRSDDIPLGEQTVAQVLHSAKEQLRWSLLK----------------------- ---------------------------------------------------------KFK ATYDSNHDTFRMEFLVVPVAGLAFLVNHDFSPLEILWTFSIYLEAVAILPQLFMISKTGE AETITSHYLFALGVYRALYILNWIYRYYFEGFFDLIAVVAGCVQTVLYCDFFYLYITK-- ---------MKIEEVKSTTKTQRIATHSHVKGLGLDESGYAHQSGAGLVGQELAREAAGI VTEMIKSKKMAGRAVLLAGPPGTGKTAIAMAIAQELGSKVPFCPMVGSEVYSSEIKKTEV LMENFRRAIGLRIKETKEVYEGEVIELTPAETENPMGGYGKTVSHVVIGLKTAKGTKQLK LDPSIYESLQKEKVEVGDVIYIEANSGAVKRQGRSDAFATEFDLEAEEYVPLPKGDVHKK KEVIQDVTLHDLDIANAKPQGGQDIMAMMGQLMKPRKTEITDKLRKEINKVVNKYIDQGI AELVPGVLFIDEVHMLDIECFTYLHRALESSLAPIVIFATNRGKCTIKGTEDIISPHGIP LDLLDRLMIIRTLPYSQEEMSQIIKIRAQIERIDISDESLQALSEVGVKTTLRYAIQLLT PGSLLANINGKQLIGREEVEEINELFFDAKSSAKVLSEQEDKYMK--------------- ------------------------------------------------------------ ----KNLHMNLDRRTGYLKGYALVEYETFGEAQKAIENLNGTEILGQKINVDWCFVRGPS KK--------------------------------LALKVLLQFDKAINNALSTRXNDRIT FKGHLNTYRFCDNVWTFVLNDVEFKRQQKXKIVACDGKG-FLFTSESVGEGHPDKICDQI SDAILDAHLKQDPNSKVACETASKTGMIMLLGEISSKAVVDYQKVVRDTIKYIGYDDSSK GFDYKTCNVLSALEEQSPDIAQGVHEGRNEDDIGAGDQGLMFGYATDETEECMPLTVVLA HKLNAKIAELRRNGGLPWARPDSKTQVTCEYRMQKGVCIPQRVHTVVISIQHSDDVTLEK LRKDLMDKVVANVIPAKYLDERTVFHMQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAH GGGAFSGKDFSKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVAEPLSIFVSSYGT GVKSDDELLKIVKNNFDLRPGRIVRDLDLKRPIYQKTACYGHFGRPDFSWEEPKKLMFMA GSALKRLMAEYKQLTLNPPEGIVAGPVDEENFFEWEALITGPEETCFEGGVFAAKLTFPS DYPLSPPKMKFTCDIFHPNIYSDGRVCISILHAPGDDPXGYESSAERWSPVQSVEKILLS VVSMLAEPNDESAANVDAAKTWRDNR-----------------MRLEKCYFCSSTVYPGH GVQFVRNDCKVFRFCRSKCHRAFKKKRNPRTVRWTKAFRKAAGKELTVDPSFEFEKQRHV PVK---ELWQDTVKAMKKIDMIRVRRQNQFITNRLKKGKELRKEADIKEVEKNIHLIKSP AVGMAAYKVVMIRHGESEYNQANRFCGWHDADLSELGVQEAKNGGQILKEKGYSFDVAFT SVLKRAIKTLYHVQDALDLHWIPVHRHWRLNERMYGALQGLNKSETAAKHGEEQVKIWRR SYDVPPPAVEISDERWPGNDPKYEMMDKNLIPRAECLKDTVNRVLPYWYDVIVPEIKRGQ RVLIAAHGNSLRAMVKYLDNMTDEAIMGLNIPTGIPLVYELDKDLKPVKHYYLASE---- -------------MEQEDIHYNKSEYIETASGNKVSRQSVLCGSQNIVLNGKTIIMSDSI VRGDLANVRIGRHCVISKRAVIRPPFKKFSKGVAFFPLHIGDHVFIEEDSIINAAQVGSY VHVGKNCVIGRRCVLKDCCAVADDTVLPPETVVPPFTLYSGSPGMSFLFGSRSNKTFKPK KNIPEGTHXYDLMKHAAATLGSGNLRLAVLLPEGXDLNEWVAVNTVDFFNQINMLYGTVT EFCTEQSCPVMSAGPRYEYHWADGHMIKKPIKCSAPKYIDYLMTWVQDQLDDESLFPSKX GVPFPRNFLSMAKTILKRLFRVYAHIYHQHFPQVIQLEEEAHLNTSFKHFIFFVQEFSLV DKRELAPLQELIDKLTSKD----------RKVARTEPKSLDIYLRLLVKLYRFLARRTNA KFNKIILKRLFMSKIHRPPLSLARLIRLMSKPGRTDKLAVCVGTVTDDMRIFKIPKLKLC ALRVTEGARARILKAGGEIITFDQLALRSPKGQNTVLLQGPRRXREAVRHFGRA---PNS XTKPYVRSKGRKFERARGRRKSRAYKN--------------------------------- ------------------------------------------------------------ ------RVVLQVLKEHFTVYITEKTGSTMYNDLSNLGIPVILILDAAIGYIMEKVDFVLV GAEGVVESGGIINKGTCTMAICAKEMNKPFYVVAESFKFARLYPLN-QDVPNQFKYRASK EHPMVDYTPPAYITLLFTDLGVLTPS-----------MIIPVRCFTCGKVIGNKWEAYLG LLQAEYTEGDALDALGXKRYCCRRLLL--------------------------------- --------------------------------------IDEETQIYEGELFHFDIEVKPI LEVLVGKTVEQSLLEVMEEEELANLRMQQRQFEELRNAELVEQQRLEEQERRHREEKERR MMQQKEVLRKEHETTEKIAARAFAQSYLADLVPTVFGTLSDNGYFYDPVERDVEQGFLPW LMGEVEERLQQAVVSRMLLDDLIRYVVSKRNKQF--MKARGELKEYKVIGRLLPTPKLRV PPLYQMRIFAPDRVTAKSRYWYFVSMLKKMKKMAGEIVLIQQIYEKKPLVIKNFGIWLRY SSRSGTHNMYREYRDLTTAGAVTQCYRDMGARHRARASSIQIMRV--------------Q FHDSKIKFPLPHRVSRRLHHPRFTTNRPHTSF-----------------------YKMHQ PMLMSLGHRISGIAMGVAFYGLIIGLYVMPGDFTHYLDLIKSFDLPKWFLFPAKMVVAFP LMYHYMNGMRHLSWDAGKGVRLATMYKTG----------SGSASLSAYRDQHFKGNRHEQ EQLLLMSSTLYIGNMSYYTTEEQIYELFSRCGDIKRIVMGLDKFKKTPCGFCFVEYYSRE DGEAAMRYINGTRLDDRVVRTDWDVGFKEGRQFGRGKTGGQVRDEYRTDYDSGRGGYGKL VKQKL------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------KLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG KWIVSGSEDNMVYIWNLQTKEVVQKLAGHTDVVLCCACHPTDNIIASAALENDKTIKLWR SDVMIIYKDIFTGDELFSDSFPDVVYKLKGKNDSLIGGNASSGVDVVMNDKKSYMTHIKE YMKRVKEYQFFCGLVLMKWETPYLFFFKHGLDEEK----------VIAADSRTSAGTYIP NRVTDKLTKVTENIYCCRSGSSADTQAIADIVNYHINFHRMEMGEDSLVKTAAKVFQDLC YNYRDSLSAGIICAGWDRKLGGQVYSIPLGGMCIRQPVTIGGSGSTYLYGHVDATFKENM TKDECLKFCKDAVSLAIMRDGSSGGVIRMAAITEEGVDKHLILHEDITKFVMIAIASGLL LLCCCFCICKRCLKKRKKKDGKKGLKGAVDLKSVQLLGSSYKEK--PDLEELEVNMEDNE DAESAKSEVKLGKLQFSLDYDFQKGELTVGVIQAADLPGMDMSGTSDPYVKVYLLPDKKK KHETKVHRKTLNPVLNESFVFKVQFADIGAKTLVFAIYDFDR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------VMFVGLQGSGKTTTCTKLAYYYQKKNWKSCLV CADTFRAGAFDQVKQNATKARIPFYGFMTKGNEQESMSRLKXLMTIMDS----------- ----------------------TDSELDSHE--GAKLFTRGRMARVARGAGVSVRDVQEL ITQKFAQMVKKMGGIKGLFKKGGDMAKNVPNQMAKLNQQMAKMMDPRVLQQMGGMAGLQN MMRQFQAGSMSIMSYNGAAIVAMKGKDCVAIATDRRFGIQAQTVAMDFQKTFEMGPRLYI GLPGLATDVQTVAQRLKFRLNLYELKENRRIRPKTLMSVVSNLLYERRFGPYFVEPVIAG LDNKTFEPYIAALDLIGCPMATDDFVVSGTCT---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------IISEWMGYCLFYESMLQTVIYARDKWLAPDGL IFPDRATLYVCAIEDRQYKDEKINWWDNVYGFDMSCIRKVAISEPLVDVVDPKQVVSNSC LVKEVDIYTVKETDLTFSAPFHLQCRRNDYVQALVTFFNIEFTKCHKRTGFSTGPDAQYT HWKQTDEYITAK---XLFGVLTMKPNKRNTRDLDFSIDIDFRGELCEMVQTMNYKMR--- ------------------------FVVSDELVGSSQMQKIRISLRVLMGKNTMMRKAIRG HLENNPALEKLLPHIKGNIGFVFTKADLSDVKTRILENKVAAPAKAGAVAPLDVVLPAQN TGLGPEKTSFFQALAIPTKITKGTIEILNDIKL--------------------------- ---------TVFDPSVLDITDDDLRARFLQGVANIASVCLAIGYPSVASVPHSIANGFKN LLAIAVETDITFKEAEMTKE---------------------------LDKHRRPNFLVVD ATTTVSEIEEAFTNFSKRDDIAIILINQNVAEMIRHILDNYTAPIPAVLEIPSKNHPYDA NKDSILRRAKGMFSADEL------------------------KLLRNYDLDEPGRLSVDE FMSLPELQQNPLXQRVIDIFDTDGNGEVDFKEFIEGISLFSVKGAKEAKMRFAFKIYDMD KDGYISNGELFQVLKMMVGNNLKDAQLQQIVDKTIILADLDGDGKISFEEFCAVVGTLDV H-------MTYINSWEEFAKAAEKLYLADPAKCRFVMKYRHCNGQLVIKMTDDRVCLQYQ TEHAQDL--------------------------------------AELYAIINTLQHLEK AYIKDSVTPKEYTANCSKLLVQYKAAFQQVKGSEFPTLESFVTKSKLNCPAAMERIKEGR PITIRDDKGNTSKCIADIVSLFITVMDKL------------------------------- -----------------------------------------------MLSSMVKEHQLKQ QARKEVQERKKKAATAATALTHSLVDYLNSGVAQAYVNQKKLDTETKILQANATHFAKQT TQWLKLVEDFNQSLKEIGDVENWARSIERDMHTISNALEYAYK----------------- --------RYYPTEDRPKKLRNSFSEHKHKLRPSLLPGTVLIILCGRHKGKRVVFLKQLK TGLLLVTGPYHLNGCPLRRINQIYVIATKTRLDISGVKLPERVNDEYFKRQKLNKPKHTE GEY----------------------------LRTXPEKKFMFGYLGSLFSLTNKQYPHK- ------------------------------------------------------------ -----------------------------------------------VTRAMAQMNKQMK LPEIQKIMMEFEKQSEIMEMKEEMMNDAIDDAMGDEDDVDESDAIVAQVMDELGLQLTDQ LSGLPDTGKSGGKQPVQVDDADADLEARLDNLRRQ---------------------ELIS CADCGNSGHPSCLQFSPALTERVRQLRWQCIECKTCSTCGEAGKEDNMLFCDACDRGFHM ECCRPPVTRPPKGVWICPLC--------ERAISLYPLTNYTFGTKEALFEKDSSVTSRFN RMREEFDKNGMRRSVEGVLIVHEHGLPHVLLLQLGTTFFKLPGGELNANEDQVDGLKRLL SEMLGRSDQVPVNWVIENVIGNWWRPNFEPPQYPYIPAHITKPKEHKRLYLVQLPEKALF AVPRNYKLVAAPLFELYDNSAGYGPIISSLPQALSRFSFIYNFTPSGTTPTGSKAMAMAT PTPGHVMSMTPEQMQAWTWQREIDERNRPLTDDDLDAMFPSGYKVLQPPAGYVPIRTPAR KLIATPXPMAGTPVGFRMQTQIVDMQPKGNLPMMKPDDMQYFDRKIMKLLLKIKNGTPPM RKAALRQITDKAREFGAGPLFNQILPLLMSPTLEDQERHLLVKVIDRILYKLDDLVRPYV HKILVVIEPLLIDEDYYARVEGREIISNLAKAAGLATMISTMRPDIDNMDEYVRNTTARA FAVVASALGIPSLLPFLKAVCRSKKSWQARHTGIKIVQQIAILMGCAILPHLKSLVEIIE HGLVDEQQKVRTITALALAALAESATPYGIESFDSVLKPLWIGIRTHRGKGLAAFLKAIG YLIPLMDAEYANYYTREVMLILIREFQSPDEEMKKIVLKVVKQCCATDGVEPQYIKDEIL PAFFKHFWNQRMALDRRNYRQLVDTTVEIANKVGAAEIVSRVVDDLKDEAEQYRKMVMET IDKIMSNLGAADIDSRLEEQLIDGILYAFQEQTTEDVVMLNGFGTVINALAKRVKPYLPQ ICGTILWRLNNKSAKVRQQAADLISRIAIVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLG SILGALKGIVNVIGMTKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGAEFVS AREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVC TTVAIAIVAETCSPFTVLPGLMNEYRVPELNVQNGVLKSLSFMFEYIGEMGKDYIYAVAP LFEDALMDRDLVHRQTSMAAIQHIALGVYGFGCEDALTHLLNYVWPNIFETSPHVVQAFM GSIEGMRVGLGSTKVLQYGMQGLFHPARKVRDVYWKVYNTIYIGAQDSMIPAYPRVPNDD KNQFIRYELDYIL----------------------------------------------- ------------------------------------------------------------ ---LDYISTSKQMELLQNFYETTLDALQEAKNDRLWFKTNTKLGKLHFDRGEYAKLQKIL KQLHQSCQTDDGEDDLKKGTQALEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPL IMGVIRDCGGQNARGGRRVRETHTQYFLRYNKHDESGSPK-----------------GIN PFDSQEAKPYKNDPEILAMTNLVSAYQNNDINEFEKILKINSVNIMQDPFIREHIEDLLR NIRTQVLVKLITPYTRIHIPFISKELNIDVLEVESLLVSCILDNTIRGRIDQVNQVLELD TGFARYSAMDKWTAQLSALHLSIVNKMA--------------------NYIARDTRRLGA TIDVEYSHVPFLSNLVLNLWDCGGQEAFMENYFASQRDNIFRNVEVLIYVFDVESRELEK DMHYYQSCLEAILQNSPDAQVFCLIHKMDLVQEDQRELIFKEREEDLKRLSKPLHINRGM RLLYKAWSSIV----------------FASIIDADEVLLFEKASFLVISHCERKAHIDMH RFEKISNIIKQFKLSCSKLAASFQSMEVHNSCFAAFVDIFTPNTYVMVIMSDPTIPSAAT LINIRNARKHFVELEKQE-ILSFSTRLFSVLRFESVIHEFDPYFNYRTTRFLVEEGFYNF HNWFDDRAWYPLGRIIGGTIYPGLMITSAIFYHLMHFIHFTIDIRNVCVFLAPLFSSLTT LVTYVLTKELKDASAGLVAAAMISIVPGYISRSVAGSYDNEGIAIFCMLLTYAWWIKSVK TGSLFWAIMCSLAYFYMVSSWGGYVFLINLIPLHVLILMATGRFSHRIYVAYSTVYCLGT LLSMQISFVGFMPIQTSEHMAALGVFGLCQIHAFIDYVRSKLSREQFSLLFRAVILMASI IVAMASGKIAPWTGRFYSLLDPSYAKNNIPIIASVSEHQPTTWSSFYFDLQMLVFMFPAG LYFCFKKLTDANIFIILYGITSIYFAGVMVRLMLVLAPVMCILSAIAVSSTLSTHMKNLD VAKKTDINYPFKNEVATSVVVLVTLFLVTYTFHCTWVTSEAYSSPSIVLSARGGDGSRII FDDFREAYYWLRQNTEEDAKVMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMSS TEDKAYEIMRELDVNYVLVIFGGLTGYSSDDINKFLWMVRIGGSTDRGAHIKETDYFTPQ GEFRIDKDGSSTMLNCLMYKMCYYRFGSVYTEQGKPTGYDRVRNAEIGNKDFELDVLEEA YTTEHWLVRIYKVKDLDNRG-HLNMRPLLRLICQRFFGEFTGFTSMCVQFIKSPLANART KVEHIYTGPVDTELAESMFECDPDGPLMVHTTKLYPT----------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ENKITM IAEPLEKGLAEDIENEVVQITWPRKRLGEFFQTKYDWDLLAARSIWAFGPDSTGPNILVD DTLPSEVDKSLLSSVKDSIVQGFQWGTREGPLCDEPIRNVKFKILDAVIAQQPIHRGGGQ VIPTARRVAYSAFLMATPRLMEPYFFVEVQAPADCVSAVYTVLARRRGHVTQDAPXPGSP LYTIKAF-----SVGFETDLRTHTQGQAFCMSVFHHWQIVPGDPLDKSIHIRPLEPQPAT HLAREFMIKSRRRKGLSEDVSINKFFDDPMLLELAKQDVMLSYNMQETFSLFDNKGDGKI YAHQLGDVLRAMGQNPTESEVRKCSDPDFRISFETFLPILSTISKNRDTSTIEDFIEGFR VFDKEQNGMINSAEL--VVSSLGEKMTDEEVNELLMGQEDAQGNVNYEEFVKMVL----- --FNIDNGYLEGLVRGFKGGILRQSDYSNLVQCDTLEDLKLHLQSTDYSTFLANEASPLT VSVIDDKLREKLVIEFQHLRTHAVEPLATFLDYITYSYMIDNIVLLITGTLHQRAISELI PKCHPLGSFEQMEAIHIAATPAELYSAVLVDTPLASYFIDCISEQDLDEMNIEIIRNTLY KAYLEDFYKFCQEMGSETAEVMCEILAFEADRRAFIITINSFGTELSKDDRAKLYPRCGK LQPDGLGALARADDYEQVRAVAEYYSEYRTLFSDVSGDAGDKTLEDKFFEHEVQLMKNAF MQQFHFGVFYAFIKLKEQECRNIIWIAECVAQRHRAKIDSYIPIF--------------- --------------LIDWSSQNVLSVGLGSCVYLWSACNQSSXRVCDLSCDNDTVTSVSW SERGGLVAVGTDKGFVQIWDVATNKRITTLDGHSARVGALAWNADVLSSGSRDRLILQKD IRTPSLVPERKLTGHRQEVCGLKWSPDHQHLASGGNDNKLFVWNVTSSSPVQTYTEHLAA VKAIAWSPHQHGLLASGGGTADQCIRFWNTLTGQPLQCVDTGSQVCNLAWSKHSNELVST HGYSQNQILVWKYPSLLQIAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTR STKESKSVLNMFTRIR---------------------------SPYQWANMGIGLAISLS VVGAAWGIFTTGSSILGAGVKVPRIRTKNLVSVIFCEAVAIYGIIMAIVIGNVKNYMAGY AMFAAGLTVGFTNLSCGMCVGVVGSGAALSDA---------------------------- -----------MAASRRLAKELQDQVDESNILLWTGLIVPENPPYSKGAFRIKIEFPAEY PFKPPKITFLTKVYHPNIDEKGQVCLPIIS------------------------------ ---------------------------------------PMQCSALRKNGYVVLKERPCK IVDMSTSKTGKHGHAKVHLVGLDIFTGKKYEDICPSTHNMQVPHVKRTEYQVIDFTNNFF CLMDDSGETRDDLK---------------------------------------------- ---------------------------------HNRKTVNDAGEKRETLFTVGLLRFVFG TKGSDTDQFDSPIGVAFNRNGDVLVADRGNKRVSTSRRDGKVKFVFD------------- ---------------------------NQDATIYVGGLDEKVSEAILWELFLQAGPVVNV HMPKDRITQAHQGYGFVEFMGEDDADYAIKIMNMIKLYGKPIRVNKASAHQKNLDVGANI FIGNLDPEVDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFEAADMAIEAM NGQYLCNRAIAISYAFKKDSKGERHGSAAERLXAVQNPLPEADRPHXLFAD--PSQQNIP LVPPPPPPVSGDRRPSHPGMPG---IPPPMPP---------------------------- ------------------------------------------------------------ ---------------------------------------------------------AEQ RMKGKDDVPTKRPPVVRSGINTVTTLVEQKKAQLVVIAHDVDPLEIVLFLPALCRKMGVP YCIVLGRVVRRKTATCLALSQVNPEDRSTLNKLIEAVKTNFNERFDELRRHWGG------ -------------------MRYVAAYLLAVLGGTASPTDKDIKKILSSVGIDADDACLKK VISELKGKDLNDVMAAGREKLTSMPSGGGAVAEEAKKD-EDD---------MSIKSIHAR QIFDSRGNPTVEVDLTTDKGMFRAAVPSGASTGIYEALELRDNIKAEYLGKGVLKAVSNV NKLIAPALVLDVTDQKAIDKIMLDLDGTENKAKLGANAILGVSLAVCKAGAAKKGVPLYK HIADLAGNKEVIMPVPAFNVINGGSHAGNKLAMQEFMLLPTGASSFTEAMRMGSEVYHHL KSVIKAKYGQDACNVGDEGGFAPNIQNNEEGLDLLKTAIEKAGYTGKIKIGMDVAASEFC KKYDLDFKNPNSKPADYLSPDQLLKMYEGFVSKYPVVSIEDAFDQDDWDSWTKMCAIQLV GDDLTVTNPKKVKEAIERKACNALLLKVNQIGSVTESIEACKMAQNAGWGVMVSHRSGET EDNFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGSKVKYAGENFRHP----- ----------------------------------KIAWKVEIEKLDYHHYLPLFFDGLCE TEHPYEFFARQGVHDMLEHGGPKILPVIPQLIIPIKNALSTRNAQVMCITLKVLQHLVVS AEMVGEALVPYYRQILPVLNIFKXKNLNSGDGIDYSQQKRENIGDLIQETLEAFERHGGD DAFINIKYMVPTYESCMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXEDHRRKWDRDEYERQALERMVKEEGKKEAPVKRDLLRPRDYRVDLES KLGKSQVITKTTPSSHQGGYFCNVCDCVVKDSINFLDHINGKKHQRNLGMSMKVERSSLE QVKKRFEMNKKKMEEKSKNYDFEERVQDMQEEEEKQRNYRREKKKDRKRK---------- --------------MGCTMSQEERLAMERSKQIEKNLKEDGMQAAKDIKLLLLGAGESGK STIVKQMKIIHEGGFTSEDNKQYKPVVYSNTIQSLVAIIRAMGTLNIAFGEPERESDAKM VLDVIARMEDTEPFSEELLHAMXRLWSDTGVQECFSR----------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YHS QFSKPPQLVGNIAVLPLRTHFKGPA-DIIDEALLFFKANVFFKNYEVRNEADRTLIYITL YITECLKKLQRCQSKNQGLKEMNSLALQRFFLPGEAQFPLNAMYARPANRSEEDMMRSYV QQLRHETGARVVEKVFDPATDKPSKWWMCFVKRKFMDKSLSAPGQTGPYNYSYIFKYIII GDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVAGQKIKLQIWDTAGQERFRAVT RSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIFLIGNKSDLEAQRDVTYE EAKQFAEENGLMFLECSAKTGENVEDAFLDTAKKIFQNIQDGSLDLNAAESGVQHKPTSP RNALNTDQAQNKEGCGC---------------------------------------HGFH VHERGRLGYRCLGAGGHFNPENMLHGGPDDNIRHVGDLGNLEEDRVTMTDHKVSLVGPHS IIGRSVVIHRYEDDLGRGGYRNSRITGHAGSRLGCCVI---------------------- ----------------------------------------TPQDEQERCITIKSTAISLY YTLPEKDLLTSFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQA IAERIKPVLFMNKMDLALLTLQLEAEDLYQTFLRTVENVNVIIGTYADDDGPMGEIMVDP TKGTVGFGSGLHGWAFTLKQFAEIYADKFKIEEAKLMRRLWGDQFYHFVRGFTQYILDPI YKVFEFCMPKEDTLKLVEKLGIKLTADDKEFQEKQLLKVVMRKWLPAGDALLQMITIHLP SPVTAQAYRIELLYEGPMDDEAGVSMKACNPKGPLMMYISKMVPTSDKGRFFAFGRVFSG VCSTGLKVRIMGPNYTPVKNIQRTILMMGRYMEPIEDVPCGNICGLVGVDQFLVKTGTIS TYDLAHNMKVMKFSVSPVVRVAVECKNAADLPKLVEGLKRLAKSDPMVQCSIEESGEHII AGAGELHLEICLKDLEEDHACIPIKVSEPVVSYRETVSAESSQMCLSKSPNKHNRLFMRA VPMPDGLPEDIDNGDVTARQEMKERARYLADKYNYDVTEARKIWCFGPDGTGPNIVCDCT KGVQYLNEIKDSVVAGFQWATKEGILCEENMRGVRFNIHDVTLHADAIHRGGGQIIPTAR RCLYASVLTAEPRLLEPVYLVEIQCPENAVGGVYGVLNRKRGHVFEEQQVTGTPMFLVKA YLPVNESFGFTADLRSNTGGQAFPQCVFDHWQELIVAVTRKRKGLSETVPSLDKFLDKMM LPLSLLRTAVNHPMLVELKNGETYNGHLVSCDNWMNINLREVICTSRDGDRFWKMPECYI RGSTIKYLRIPDEVIDMVKEEVIVKGRGRGE--MRGRGGPGRGAFGNRGGRGGRGGRGGP TGVNEFKLNNPPTDGVSAVKFSPVSPQFLLVSSWDCSVRLYDTNNNSMRIKYTHSAPVLD CCFYDTVHSYSGGLDKTLKAYDFNSSTETIVGQHEQPIRCVEYCPDVNVIVTGSWDSTVK LWDPRAPCSAGSFSQPDKVYTLSLCGDKLVVGTAGRRVLVWDLRNMGYVQQRRESSLKYQ TRCIRCFPNKQGYVLSSIEARVAVEYMDPSPEVQKKKYAFKCHRIKEDGVEKIFPVNAVA FHGSFNTFATGGSDGFVNIWDGFNKKRLCQFHRYPTSIASLSFSCDGTLLAIASSYMYED GVPEDAVYIRKVSDAETKPK---------------------------------------- ------------------------------------------------------------ ---VDIKKFVKIGRPGYKVTKQRDPENGQQSLLFQIDYPEIVDGVIPRHRFMAAYEQKVE PPDRKWQYLLFAAEPYETIGFKVPSREVDKDAKKFWSHWNLETKQFFLQFAFKNDPRKMP PPLPAGLPPPPMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------LLTIDSGVFEVVSTNGDTHLGGEDFDQRVIDYFIKVYKKKKGKDIRT SNRAIQKLRREVEKAKRTLSSQHQARIEIESLFEGEDFSEMITRAKFEELNMDLFRSTMK PVGKVLEDADMKKTDIDEIVLVGGSTRIPKVQQLVKEYFGGKEPSRGINPDEAVAYGAAV QAGVLSGEEDTGEIVLLDVNPLTMGIETVGGVMTKVIGRNTVIPTKKSQIFSTAADNQPT VTIQVFEGERPMVKDNHLLGKFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGN KNNIVINNDQNRLSPEDIERMINDAEKFADDDKKVKERVEARNELESSAYSLKTQINDKE KLGAKLSSDEKSTIEKAVTEQIEWLEKNPEAEVEELKEHKKALDEIVQPIISKLYQGAPP P----------------------------------------------TPEERLEADGRSI YIGNVDYGATAQELEAHFHGCGSVNRVTILCDHFTGHPKGFAYIEFADKESVQTSLALDD SLFRGRQIKVSAKRTNRPGISSTDRPPRGRGFRGRGRGFYYGYTPRGRGRG-YRSRRASY YSPYVLYSTLVELAQAATFHTLTDAVNNEKGKKAALQEMILKEEEGRRRVKALQKQLVDV RREKEVELQHRNEMIAHLKDQLQEMKAKTSMEGKYIKKVAEVSVAQAQKKCGLTEKQMRD DIKDLKTKIDEETRVNAEVESYLLGHTKRLQKQVEHWMEKYDTDVEQKQKELDILKASKA KDLERLQYLTKLYSDYEQVVVEDRIEKEKARRKAELEAEQLKCAVEXRAWWRGMMVRKCL GAFSKKKGKK-------------LVLRAALKAVNVVAVNDPFIDLQYMIYMFKYDSTHGR YEGSVTLVIEGKPIEVFMEKDPAKIPWGKSGADYVVDSTGVFTKIDAAKAHLQGGAKKVI ISAPSADAPMFVMGVNQDKYDKSMNIVSNASCTTNCLAPLAKVINDKFGIVEGLMTTIHA YTATQKTVDGPSSKAWRDGRTAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPVPDV SVVDLTCRLNKGASFDEIKAAVKGSMKGILAYTEEQLVSTDFLTTTVSSTFDAGASIVLN ANFIKLVAWYDNEFGYSCRVVDLIKYMYGRD----------------------------- ------------------------------------------------------------ ---------DVKYGKRVHVLPIDDTVEGLTGNLFEVYLKPYFLEAYRPIHKGDIFLVRGG MRAVEFKVVETDPSPYCIVAPDTVIHCEGEPVKREEEEEALNEIGYDDIGGCRKQLAQIK EMVELPLRHPQLFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSK LAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQ RSHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDPTGRLEILRIHTK-MKLADDVDLE QVAAESHGHVGADLAALCSEAALQQIREKMDLIDLEDDSIDAAVLDSLAVSQANFRWAMS KSNPSALRETSVEVPNVSWNDIGGLENVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFY GPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFD ELDSIAKARGGNIGDGGGAADRVINQLLTEMDGMSSKK-VFIIGATNRPDIIDPAILRPG RLDQLIYIPLPDDKSRVMILKANLRKSPVSRDVDLEYLAKITKGFSGADLTEICQRACKT AIRECIEAEIRRERERDENPDDYDPVPEVRRDHFEEAMKYARRSVTDNDIRKYEMFAQTL QQSRSFGG---------------------------------------------------- ----------------------------------------------DKSAKMWDLGSNQF VQVAQHDAPIKSCHWVKAPNYNCLMTGSWDKTLKFWDLRSSNPMLVINLPERCYCADVVF PMAVVGTAGRQVIIYTLESEPREFKRIESPLKFQHRCVSIFPDKKTNAPTGFALGSIEGR VAIHYVNPQNPKDNFTFKCHRGGVQDIYAVNGIAFHPVHGTLATVGSDGRFSFWDKDART KLKTSDQLDQPISACGFNAQGNIFGYASSYDW---------------------------- ---MSSPSPGKRRMDTDVVKLIESKHEVTILGGLNEFIVKFYGPQGTPYEGGVWKVRVDL PEKYPFKSPSIGFMNRIYHPNIDEVSGTVCLDVINQAWTALYDLSNIFESFLPQLLTYPN PIDPLNGDAAALYLHKPEDYKK-------------------------------------- ------------------------------------------------------------ DTAGQERFRTLTPSYYRGAQGVILVYDVSSKQSFTQLGNWLNELETFSTKHDIVKMLVGN KIDKDRREISRDEGLKFARKHHMLFIEASAKTKEGVQCAFEELVEK-------------- ------------------------------------------------------------ ----------------------------------------------KQRFTKIIQYLIRI RKLTLKRQKKLVPLSRKVERRETRREEKALVAAQLENAIEK------------------- ------------------------------------------------------------ ----------QEYQLDLNHTGVMILDALIKIKNEIDPTLTFRRSCREGICGSCSMTVDGV NTLACLCKINQNTNQTTSVRPLPHMFVIKDLIPDLNNFYAQYRFIEPWLKKKDVKDADMG NTQFLQSPEDR-KLDGMYECILCACCSTSCPSYWWNGDKYLGPAVIMQAYRWVMDSRDQ- --------RDKWMVYRCHTIMNCTKTCPKGLNPGAAIAELKKLMMGYESKGIPYQ--QPN HTIYINNLNEKIKKDELKKSLYAIFSQFGQILDIVAMKTLKMRGQAFVIFKDINSGTNAL RSMQGFPFYDKPMRITYAKRDSDVIAKMKGTFVERPKR-------------VPAAIPEQP PHHILFLTNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENEAQAGAAKDALQ GFKITPTNAMKISFAKK------------------------------------------- ------------------------------------------------------------ --------------KNREKMVEVMFEQYKFEGLYIAIQAVLTLYAQGLLTGVVLDSGDGV THICPVYQGFSLPHLTRRLDIAGRDITNYLIKLLLLRGYAFNXTADFETVRMMKEKLCYV GYDIEQEQKLSVETTVLVESYTLPDGRVIKVGGERFEAPEALFQPHLINVDGIGAAELLF NTIQAADINIRSDLYKHIVLSGGSTMLPGLPSRMEREXKQLYLERVLKGDTEKLAKFKIR IEDPPRRKHMVFLGGAVLADIMKDKDSFWMTKKEYDEQGLRVLAKL-------------- ------------------------------------------------------------ -GGVVESVGEGVTSIQPGDHVIPLYIPQCGECKFCCNPKTNLCSKIRSTQGSGVMPDGTS RFTCRGKQLYHFMGCSTFSEYTVVAEISVCKVEVTAPLQKVCLLGCGISTGYGAALNTAK VEAGSCCAVWGLGAVGLATIMGCKKAGAARIIGIDVNPKKFDIAKEFGATECINPKDFDK PIQEVLVAMTDGGLDFTFECIGNVATMRAALEACHKGWGVSVIIGVAAAGQEISTRPFQL VTGRVWKGTAFGGWKSRDSVPKLVDEYMAGKLKVNEFV---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GTGVTHAVPIYEGFAMPHSVM RVDVAGRDVSKYLQMLLRKEGHKFHTSAEFEIVRTIKERVCYLSLNPQKEETMKTEKTQY KLPDGSTLEVGSARFRAPELLFRPDLIGEECEGIHEVLTYAIRKSDMDLRRTLFSNIVLS GGSTLFKGFGDRLLSEVKMLAPKDVKIKISAPQERLYATWIGGSILASLDTFKKMWVSKR EYEDEGMRAIHRKTF--------------------------------------------- -----------------------------------------------------KLHQNDV RINELIRRYCPNSVLVIIDAKPKDLGLPTEAYIAVEEVHDDGTPTSKTFEHVPSEIGAEE AEEVGVEHLLRDIKDTTVGTLSQRVTNQLMGLKGLFSQLRDIENYLEKVSMGTLPINHQI IYHLQDIFNLLPDINLREFVRSMYIKTNDQMLVVYIAALIRSIIALHNLINNKIQNRDAE KNEG----MGLFFSKLWALFTNEEHKVIIVGLDNAGKTTILYQFLMNEVVHTSPTIGSNV EEVIWKXIHFLMWDIGGQESLRSAWNXYFTNSEFVILVIDSTDRERLSITKEELYXMLAC EDLK----------------------SQQLNLTSVKDHIWHIQACCALTGEGLYQGLEWI TNHIRRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXX-------------------------------------------- ------------------------------------------------------------ -------------------------------------------------VSGHVKTQLIA HDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLAWNKQ DPNYLATMAMDAMEVIILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQAL IWDIQQMPRAIEDPILAYTAAGEINQIQWSSTQPDWIAICYNNYMEILRV---------- ------------------------------------------------------------ ---------------------------------------CAQYCPKAMICIICNPVNSTV PIASEMFKKRGVYDPNRIFGVTTLDIVRSNTFISQAKGLDVNQVNCPVVGGHSGVTIVPV MSQCTPPVSFPAEERQKLSVRIQNAGTEVVEAKAGTGSATLSMAYAGARFIGSILDGLNG EEGIVECAFVRSDETEAKYFSTPLLLGKGGVEKNLGLGKLTDFEVDLIKSAMPELKKNIQ KGEDFVLKS--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------LAEKEGAYCSTYTHCEIHPAMILGVCASIIPFPDHT VA-RNVXSLXMGKQAMGVYITNYHVRMDTLAHVLFYPQKPLVTTRSMEYLRFRELPAGIN AIVAIASYTGYNQEDSVILHEGAVDRGFFRSVFYRSYKDSESKKGMDQEEIFEKPDRNFV QGMKPGDYSKLDDDGIIAPGIRVSGDDVLIGKTLTLPENEDELEGQAKRFTKRDASLCMR RTETGVIDQVMVTLNQEGYKFCKIRVRTVKTPQTGDKFASRHGQKGTCGIRYRSEDMPFT AEGLYPDIIVNPHAIPSRMTIGHLIECLQGKVSANKGXIGDATPFNDTVNXRKISNLLHD YGYHLRXNEVLYNGHTGRKVETKIFLGPTYYQRLK-----------RGPVQILNRQPMEG RSRDGGLRFGEMERDCQIAHGAA------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------GGVDSAGPHLY SIWPHGSTDVLPYVTMGSGSLAAMSVFESRYKPGISREDGMKMVRDAIAAGIFNDLGSGS NIDLCVITKKVDYIRPYDEANKKGVRQGKYTYKKGTSCVLTEKVRKVEFEIE-------- ----------------------------------------------------------FL KHGSELRLIPRDRVG-MAFTFAAFAYIVALLFTACLIFFVIYHIIGFDELKTDYKNPIDQ CNNLNPLVLPEYLLHLTFNVLFLFAGEWTSLLLNCPLIAYHVNRYMNRPVMSGPGLYDPT SIMNADQLNRAQK---------------------------MGLLTILKKMKEKEKEMRLL MLGLDNAGKTTILKKYNGEDIDTISPTLGFNIKTLEHKGYKLNIWDVGGQKSLRSYWRNY FESTDGLIWVVDCADRRRMVDCKRELDSLLLEERLAGATLLVFANKQDLPGALPSHDVKE ALDLDSIKSHHWLIQGCSAVTGENLLQGIDWITNDIASRIFTMDHSKKKICYYYDGDIGN YYYGQGHPMKPQRMRMAHNLLLNYGLYRKMEIYRPHKATQXRMTKFHSDDYIKFLRCIRP DNMSEYNKQMQRFNVGEDCPVFDGLYEYCQLSAGGSVAGAVKLNKQATDIAINWAGGLHH AKKSEASGFCYVNDIVLGILELLKYHQRVVYVDIDIHHGDGVEEAFYTTDRVMTVSFHKY GEYFPGTGDLRDIGAGKGRYYAVNFPLRDGIDDDCYETVFEPVMAKVIETFQPGAIVLQC GADSLSGDRLGCFNLSLKGHGRCVEYIKKYNLPLLLLGGGGYTIRNVARCWTYETSIAVG VEIANELPYNDYFEYYGPDFKLHISPSNMTNQNTPEYLDKIKTRLFENLRMLPHAPGVQM QDIPDDGIKDELTKRDPMSMTSSDKRVACEEEFFDSDDEGAR-------------SAGAF ECNICLDTAKDAVVSMCGHLFCWPCLHQWLETRPNRQLCPVCKAGISKDKVIPLYGRGST NQQDPRDKIPPRPQGQRAEPETNTNFPGFGFGFQMSFGIGAFPFGFFASTFNLNTGRPPA PAPGTPQFQEDQFLNKIFLWVAMLFIFWLLIA---------------------------- ----------------------------------------------ASSSLDSHIRLWDV EVGKQIKTVDAGPVDAWTISFSPDSRFLASGSQTGKINLFGVDSGKKESSLDTRGKFTLS IAYSPDGKYIACGAIDGIINIFDMSTGKLLEGHAMPIR-----------XNASDDSHIKI YDVQHANLAGTLSGHGSWVLNVAFSPDNTHFVSCSSDKTVKVWDAGSRQCVHTFVDHTDQ VWCAKYNSTGTKIVSVSEDRAVHIYDSP-ESAEEFDNRYEAFFNRQDVDGWDIRKAMNDL QGLDLVPEPRIVIAALKACRRVNDYALAVRYMEAVQNKCGDKVGEIWPYLRQEIKPTLDE LGILTPEEMGYDKPELAVEDVMDM------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------DHQSSTGHSIHMRGLPFAANEQDVMEFFKPITPVNVVIH FNSGRASGEADVDFASHEEAKEGMKRDRASMQHRYIELF--------------------- ------------------------------------------------------------ ----------------------------ISESFQRVASKAVEILEEMSTPLQLSDRDSLL KSATTSLNSKVVSQYSNILSPLCVDAVLKVIDPKKDTNVDLHDIKVIQKLGGTVEDTELI DGMVFNQKSAGTGGPHKIEKARIGLIQFCISPPKTDMDNQVVVSDYAQMDRVLREERQYI LNIVKQIKKAGCTVLLIQKSILRDAVNDLALHFLAKMKIMVIKDIEREDIEFVCKGLSCR PVASLDHFTPETLGTAELVEIVQTGSSKIVKVTGIANPGKTVSIV--------------- -------------KRALIAGGGAPEIELSIQLMEYAQTLAGVEQYCFRAFADALEIIPFT LAENAGLNPIATVTELRNRHSQGEKTSGINVRKGAITNILEENVVQPLLVSTSAIQLAAE TVRSILKIDDIVICQMILLEINNRIVEETLSLKFKNAMAGLKPEVVDITVADFDGCLYQV SNPSGDKSKITVSISLKFYQDLQEHGADDLIQRVYGPFLTTPEPGYNITLLFDENLPSDQ GAVIKKVGLLKRNCFASVFEKYFDFQMQHKRAIIHYREDETMYVDAMKDRVTVIFSTVFK DDDDVIIGKVFMQEFKEGRRRYQQAPQVLFTHKEPPLELKNTDARVGENIGYITFVLFPR HEARDNTINLIHTLRNYLHYHIKCSKAYIHSRMRAKTSDFLKVLNRARPEQKTVEKK--M LMFCPICANVLVIEEGPKCYRFACNTCPYVHNVTRKITDRKYPKLKEVDDVLGGAAAWEN VDSTAETCPKCSHGRAFFMQIQTRSADEPMTTFYKCCNMQCSHQWRKTSFGGLKDEDRIF TNLYGRHDWKLKGAMSRGDWYKTKEILLKGTEWIQNEVKTSGIRGRGGAGFPTGMKWSFM NRPADGRPRYLVVNGDEGEPGTCKDREIMRHDPHKLVEGCLIAGRAIGACAAYIYIRGEF YNEASNMQIALREAYEAGLIGKNACGSGYDFDIYIHRGAGAYICGEETALIESIEGKQGK PRLKPPFPAEIGLFGCPTTVNNVETISSAPIICRRGGDWFASFGRERNRTVLMDFDALTE AQSAFGTAAIIVMNDSADVIKCIARLMEFYKHESCGQCTPCREGVGWMQKIVARFVTG-- -----DMLYELSKQIEGHTICALADGAAWPVQGLIRHYRPQLEQRMREHEEKHFTQEQVE EMNQQLSQTRSQRVRAAMFPETLEEGIQIPSTQIHMDQPTAVQRLAEPSQMLKHAVVNLI NYQDDADLATRAIPELTKLLNDEDQVVVSQAAMMVHQLSKKEASRHAIMNSPQMIAALVR AMSNTNDVETTRCAAGTLHNLSHHRQGLLAIFKSGGIPALVKLLSSPVESVLFYAVTTLH NLLLHQEGSKMAVRLAGGLQKMVALLQRNNVKFLAITTDCLQILAYGNQESKLIILASGG PGELVRIMRSYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMPALAMHLGHQSQRLVQN CLWTLRNLSDAATKAETIGGLLQMLVQLLVSNDINIVTCAAGILSNLTCNNQGNKVMVCQ VGGIEALVRTILQAGDREDITEPAVCALRHLTSRHPEAEMAQNAVRLHYGLPVLVKLLNP PSRWPLIKAVIGLIRNLALCPANHAPLREHGAIPRIVQLLIRAHQDTQRQQGAYVDGVRM EEIVEGTVGALHILAREAHNRAVIRSLNCIPLFVQLLYSPIENIQRVAAGVLCELAADKE GAEVIEQEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRGE QMSADLQWMITRNTSCFLVKRSFFSREPNNLYNRHGKRASGLVNQQSVGIQACTDDKGVI FVTKSNWRKPAKSTTKIILKQGNRRTLNTIRKVIRSNRCRKDQKMAALRRASAILSSQRP LAARRTTDEPYYTSEQINIPPELPDILKQFTKAAIKTQPKDVLAWSAAYFRALANGETPP VKERLEMPIATQKTDTGLTPGLLRVLNKQLGPKKTVPLSLIEEKWKDLGLPKEQFDELSR IGGFSGTVDWLKFFSLACSALGENITDAMVTICEILTADPEGGAARIPYPLFQDLYRYLA EVDGEISQEHTKTVYDYLAYYVDKQDGFVQPRNFTTGDCPKLSGKFDGAQKGQLMEQVKA QIAVANAQELLQKMSDKCFKKCISSPGSSLGNSETKCIAMCMDRYMDAWNVVSRTYTQRL QRERNK------------------------------------------------------ ------------------KKMYEQQREQLMQQSFNLEQSNFSIQMMKDTKTTVDAMKSGV KEFKREYKHIDIDQIEDLQDELEDMSEQAGEIQEIMGRSYGMPELDEDDLEAELDALGDE MALDEDTSYLDEAAKAPNAPTGVPGSASVASQEGVPVDEFGLPQIPAQ----NSATPASP QLQNIVCTVNLVCRLDLKKIALHARNAEYNPKRFAAVIMRIRDPRTTALIFSSGKMVCTG AKSEEQAKLAARKYARIIQKLGFHAKFLDFKIQNMVASCDVKFPIRLEGLVLTHGQFSSY EPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKVRQEIYEAFESIYPNFEGIQE------ --------------KTDVEVFLYEVLTTEQIVQHMVDCIKEVNTVVQIPATTTRILLNHF KWDKEKLMDCYYDGDQEKLFLEAHVISPFKKTPEVTCEICYLSLPTLMTGLECGHKFCMQ CWTEYLTTKIMDEGMGQTISCAAHNCDILVDDATVMKLVKDPKVKLKYQHLITNSFVECN RLLRWCPMPDCGHVVKVQFFDSKPVTCICGHNFCFACGENWHDPVKCMWLKKWIKKCDDD SETSNWIAANTKECPKCHSTIEKDGGCNHMVCKKCRFDFCWVCLGPWEPHGSSWYNCNRY DEDEAKKARDSQEKSRSALQRYLFYCNRYMNHMQSLKFEXQLYASIRLKMEEMQQHNMSW IEVQFLKKAVDVLCQCRQTLMYTYVFAFYLRKXYQSIIFEENQKDLENSTEHLSEYLERD ITSDMLXDIKQKVQDKYRYCESRRKVLLDHVHEGYERTVG----MATTDGKLSTTERIIK SVPFPPNHKLTMHEVFDPKAKPKPDILKQHFILEGRVTEDVALRIINEGAALLRQEKTML DIEAPVTVCGDIHGQFYDLMKLFEVGGTPSTTRYLFLGDYVDRGYFSITERVYDACMEAF DCLPLAALMNQQFLCVHGGLSPEMHTLEDLRKLDRFKEPPAFGPMCDLLWSDPLEDFGSE KTTEHYSHNSVRGCSYFYSYAACCDFLQQNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSL ITIFSAPNYLDVYNNKAAILKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVT EMLVNVLNICSDDELMSEGDDTFEGTVAARKEIIRNKIRAIGKMARVFQVLREESESVLQ LKGLTPNGLLPIG----------------------------------------------- ----------------------------------------------------RGKEDVLV TKNLVPGEVVYGEKKIVVEENIKIEYRAWNPFRSKLAAAILGGVDNIHMAPGQKVLYXGA ASGTTVSHVADIVGPEGLVYAVEFLHRXGRDLINVAKKRTNIIPIIEDARHPHKYRMLVG MVDTIFADVAQPDQARIVAINAHNFLKTGGHVVISIKANCIDSTAAAEAVFASEVNKLRA EKIKPREQITLEPFERDHAVVVGQYRAPPKK----------------------------- -------------------RAIMFNRIGGVQQDVYSEGLHFRLPWFQYPIIYDIRARPRK VTSPTGSKDLQMVNISLRVLARPNVTKLPELYRQLGTDYDDRVLPSLCNEVLKSVVAKFN ASQLITQRQAVSLLMRKELTERAYDFHIILDDVAITDLAFSNVYTAAVESKQVAQQESQR AQFIVEKAKQERQQKIVQAEGEAASAKMIGEAVAANPGYLKLRKIRAAQNIARTMAMSKN RVYLNAGTLMLNVN---------SYTGSSSDEEATNPKEKEQSNSKGTSDFCVHVAQAAF GRREIEIAQQEMPGLMALRKRAQADKPLSGAKVVGCTHITAQTAVLIETLSALGAQVRWA ACNIYSTQNEVAAALAEAGFPIFAWKGESEADFWWCIEKCISADSWQPNMILDDGGDATH LMLKKYPAMFSMVKGIVEESVTGVHRLYQLSKSGKLTVPAMNVNDSVTKTKFDNLYSCRE SILDALKRTTDVMFGGKQVVVCGYGEVGKGCCAALKGLGAIVNVTEIDPICALQACMDGF RVVKMSEIARTTDLVITCTGNKSVVTREHMDRMKNGCIVANMGHSNTEIDVNSLRTADLT WERVRSQVDHIIWPDGKRIILLAEGRLVNLSCSSIPSFVVSITSATQALALIELYNAPAG RYKQDVYLLPKKMDEYVASLHLSSFDAHLTELSDEQAKYLGLSKAGPFKPNYYRYXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXX---------------------------------------------EGVKGL YLGATPALKTAVVFLSYGVCEETIAMAGILSSFVLCPLELLKCRLQAIAKGVLRTEGVRG LYRGLPGIWAKDVPGSFIYFGSYEMAKSFVKKIGP-EHQLGVDVFLCGMFAGLC-YCVTH PIETVKTRVQVKTEGLRPMCSGMKPSMLRASIYSGVQFVTYEAVKDYFL-----YNELVD VITSSIFKINNNATTLERAAKSVGTKKDSVDLRDRIHKTEQDTNRLIGDTTQVFKQLSGL RRSERQQKLQYERLTNEFKESVQRYNTLQKGVAAQVKSAVINADLSLIHDREERIVQLES DILDINEIFRELGTLVHEQGEVIDTIQDNVESGHVDEGNEQLIQASKYQRKARKKMCILV LILIVVGSVIALAIGLSLKMVNVMKGILVECDPAMKQFLLHLDDSNALGKKFVMQDLDET HLFISSDILDTLQNQINELMDKLSFPIGKKGEAPPSPQEAIQRLRGIEEMLQKKTDFLEN KIEQELSIARKRVALQALKRKKRYEKQLTQIDGTLSTIEFQREALENSSTNTEVLKVMGD AAK---------DVDDVHDLMDEVAEQQEIANEISEAISSPVGFGQDVDEDDLLAELEEL EQEALDEQLLEVGDLPSVPTAEEDEMKELAEWAT-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------YGKKNNVNVASLTQSE IRDIILGMEISAPSAQRQQIAEIEKQTKEHSQLTATTTRTVNKHGDEIITSTTSNYETAT FSSKTEWRVRAISATNLHLRTNHIYVSSDDIKETGYTYILPKNVLKKFIIISDLRAQISG YLYGVSPPDNPQVKEIRCIVMPPQWGTHQTVHLPNQLPQHEYLKEMEPLGWIHTQPNELP QLSPQDITTHAKVMADNASWDGEKTVIITCSFTPGSCSLTAYKLTPSGYEWGRQNTDKGN NPKGYLPSHYEKVQMLLSDRFLGFFMTPSQCPWNYNFMGVRHDPAMKYEVSLTNPKEFYH EVHRPSHFLNFSSLEESADHEDFY--------NMLVNKNTKVICQGFTGKQGSFHSEQAL EYGTNMVGGVSPGKGGKIHLGLPVFNSVKEAKEETGAEVSVIYVPPPFAKDAIIEAIDAE IGLIVCITEGIPLHDMVRVKYKLVRQNNSRLIGPNCPGIIKPGECKIGIMPGHIHKPGSI GIVSRSGTLTYEAVQQTTDVGLGQSLCIGIGGDPFNGSDFIDCLSVFLNDPQTDGIVMIG EIGGEAEEMAAKFLIENNGPNRKPVASFIAGMTAPPGRRMGHAGAIIARGKGGAQEKIQA LKDAGVEVTMSPAQMGSTIYKAMVKAGKPNTETLKCTLCLERLEDTHFVQCPSVPEHKFC FPCSRDSIKSQGAGSEVYCPSGKKCPLVGSNVPWAFMQGEIATILGFNRFIEIGRVAYVA FGPDEGRLIAIVDVIDQNRALVDGPRSGVGRKSMNFKQMHLTKFVVIPPGARTGTLIKAW EKQEITKKWEETTWAKKIAQRELKSGLSDFDRFKLMKAKQSRNRLINIQLGKLKIRTTKT CPLLLRVFCSTGRHHPLNEYARGNTPANELQIYTWLDATLKELTSLVKEVNVDARKKGTF FDFAIVYPDPRTPAYRMRDIGATCAGRKGMD---TLALKRFQIGDFLDISISPPR----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------VLLDKLLVKLKTQDSRVLIFSQMTRVL DILEDYCAWKGFEYCRLDGQTAHEERQSSIDAFNAPDSTKFVFMLSTRAGGLGINLATAD IVILFDSDWNPQVDLQAMDRAHRIGQKKQVKVFRFITENTVEDRIVEKAEMKLRLDNVVI QQGRLTDAST-KEVLSMIRHGANHVFASKESDITDEDIDAILARGEKKTEEMKKKMEGLG EHTLQTFTLDTPEHSVYQFEGEDYRGKQKI-GIGNWIEPPKRERKANYAVDAYFREALRV GNPXAPRAPRPQTRCQASS---STTRLFELLDXEIYYYRKTIGYRYPR------------ ------------------------------------------------------------ -----------------------------------KIQRRISIKRALDCKMARYRAPFHQ LRLQYGTNKGKNYTEEEDRFLVCMLHQLGFDKENVYDELRTAVRQAPQFRFDWFIKSRTA MELQRRCNTLITLIERENMELEEREKAEKKK----------------------------- --------------KKVKVVRTYKTETRKVPPSIAKRKTWKKFGAASNDAPGPNPSNTIE EIFMQFVHTKENAEEDPLAKLKVSCRICKGDHWTTKCPYKDTLAPPQENTQRLGKYVPPN MRDGGNRRGETMMGDEAATIRVTNLPEDTIEADLQELFRPFGSISRIYLAKDKATGQSKG -------------------------------------MSETYDFLFKFLVIGSAGTGKSC ILHQFIESKFKQDSNHTIGVEFGSKVVNVGGKSVKLQIWDTAGQERFRSVTRSYYRGAAG ALLVYDITSRETYNALTNWLTDARTLASPNIVIVLVGNKKDLEAEREVTFLEASRFAIEN ELIFHE------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------GALFQRPPLISAVKRQLRVRTIYESKLIQYDHERNMG IVWVSCEAGTYIRTLCVHLGLILGVGGQMQELRRVRSGILSEKDGMVTMHDVLDAQWQYD HMQDESYLRRIIRPLEALLVSHKRIIMKDSAVNAICYGAKIMLPGVLRYDDGIELNDQIV ICTSKGEAVALAIAQMTTAVLATCDHGIVAKIKRVIMERDTYPRKWGLGPVASRKKQLIK EGKLDKFGRANESTPKDWSKSYKDLS----------------------MAQSGWDKKRMP KSGQLHTEKALSIAQRQGLELETSKKFAAGQNKQHLTSKNTAKLDRETEELHHDTVSIDV ARLIQQARQAKGFTQKDXATRVNEKQQVINDYEGGRAIPNQQIFAKLERTLGVKLRGKDR GKPLQPKMLKPKALTQVLAQANTGGVQSTLLLNNEGALLAFSGYGDKDARVTAAIASNIW TAYDKSGRAAFDEDQLQFVLMDCEDGKVAITRVANLLLCIYAKKSVGLGLLKAKAQALAT YLEEPL------SAATARIQPKKQTLDDAYAPPANFLEIDVISAEGKKRYTDYEVHMRTN LPVFKVKESSVRRRYSDFDWLRGELERDSKIVVPPLPGKAWGRQLPFRGDEGLFDEEFIE ERRKGLEQF-------------------------------------RSYSARLMEVGVLE SPRLQGKYDTGQLFLHKVFGYRGVVLFPWVGKVYDRDIAVKASKEVKGCTHTYYQVLIDA RDIPHIRVGTESVTFLSNQENGTLYSIPGLDYVSHEDVLPYKTTESQPIHNHLFDKFLAH DQTYVARDTLREWQDKNHPWLELTDVHRETTDNIR---------EVQQAHVYWWRYCIRL ENLGEESVQLRERHWRIFSLSGTLETVRGRGIIGKEPIFSKAQPAFQYTSHVSLQAPSGH MWGTFKMEREDGTTFECRIPPFSLESRQEEG----------------------------- ------------------------------------------------------------ ---------------------DVNKEYYTQNMEREIANTDGTTPVGSVGKAKAVSDMLLK LARTTPYYKRNRPHICSFWVKGECKRGEECPYRHEKPTDPDDPLADQNIKDRYYGVNDPV ADKLMERYASMPALDPPEDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXX----------------NADEDMVKAKKLLLDGERELFLKQHPQRIRFANSVGGVS FGREVLHPDWMLDMWHPLERAQYPEYFARREQRKEEYIKRWEDKYG---MENFQKIEKIG EGTYGVVYKAKDKAAGRMVALKKIRLDTESEGVPSTAIREISLLKELDHPNVVXLLDVVH SEKKLYLVFEYLNQDLKKYVDNSPVAG-LSHPLVKSYLYQLLQGIAYCHSHRVLHRDLKP QNLLIDVAGNIKLADFGLARAFGVPVR--------------------------------- -------------------------------------------------XPCWKTNTLAQ SVDVNGMDLLQKTLIYDPAARITAKDALLHPYF-------------GIAVLGGVVNTALY NVGGGHRAVIFDRFAGVKDVVVGEGTHFLIPWVQKPIIYDIRSRPRSVPTVTGSKDLQNV NLTLRIIFRPMASELPKIYKTLGIDYDDRVLPSIVNEVMKAVVAQFDASELITQREVVSQ KINEDLTNRASQFGLILDDISITHLTFGTEFTQAVEMKQVAQQEAERARFVVEKEEQKKQ AAIIRAEGDSIGADLLAKAFGLAGEGLVELRRLEAAEDIAYQLSQAPNVVYLPSGQQTLL SLP-------------------------------GTLRRSFRHMAVDMKMIGKKKLQVEK WMGIRKELAAVRTICSHIENMIKGTQFGFRYKMRSVYAHFPINITITESNTCVEIRNFLG EKYTRQVIMRPGVTCQQSTKLKDELILEGNDIELVSQSAALIQQSTKVRDKDIR------ ------------------------------------------------------------ -----------------------------QSMIAIIRAMGQLKIDFGARERADDARQVFT LAGNAEDGEMSYELAQTMKRLWKDPGVQECFSRSREYQLNDSAEYYLNALDRISQPNYIP TEQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFIVAMSE YDMTLAEDQEMNRMMESMKLFDSICNNKWFTDTSIILFXNKKDLFEDKIRKSPLTICFPE YSGSNTYEEAAAYIQMTSNKRR-------HFTTATDTSNIQVVFQVVMDTIIKDNI---- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------KCYIVATCDKDLKRRIRKVPGVPIMYLQQHKFSI ERMPDAFGAPR------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------IFA LKWNKKGNYILSAGVDKTTIIWDASSGHCTQQFAFHSAPALDVDWQTNTSFASCSTDQCI HVCKLGVDKATKTFQGHTNEVNAIKWDPQGNLLASCSDDMTLKIWSMKQDNCVHDLQAHS KEIYTIKWSPTGPGTNNPNAPLILASASFDSTVRLWDVEHGVC----------------- ------------------------LVHSYRGTGGIFEVCWNHRGDKVGASASDGSVFVLD LRKNSSDLASLFECPVCFDYALPPIMQCQSGHIVCSNCRPKLQACPTCRGPLGNIRNLAM EKVASQVMFPCKYASTGCPVTLPHTDKQEHEDACEYRPYCCPCPGASCKWQGALEQVMPH LMQQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGQNFMLVLEKQEKYECNQLFYA IVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHDGVQHAINNSDCLVFDTNIAQLF ADNGNLGINVTISTCMAYQSFQQEYMQMPPSTRAYTTACVLTXLAVQLDLITPFQLYFNP DLILRHYQLWRLVTNFMFFGTIGFNFLFNMIFTYRYCRMLEEGSFRGRTADFFFMFIFGG LLMTIVVNLVFLGQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPYLPWVLLAFSLLLGNS VVVDMMGIAVGHIYYFL------------------------------------------- ----------------------------------------------KVICAVYGPREV-- TKRESMKGQLMCEVKFATFSCHKRRGH-QSDKRDSEYSILLQNALEPAILLEKFPKARMD VFVIVLQDDGSALAAAISCASVALASAGVEMYDLVAGCSMTLSGDVKLHDPSTEEEYNPG GVTVGLMPSLKQISALSQEGEM-----------------------------MSGNYYFVI VGHHDNPIFEMEFMPPSKATRIRXXXR-------XXXSCTGCDDXCXATSGMYLKIVDKF NEWFVSAFVTASRMRFVMLHDTKNEDGIKNFFQDVYETYVKYAMNPFYELNAPIXSAAFE KKSQFFGRKFL------------------------------------------------- -VVEFVSSMSASADVLALAKIEVSLADIPEGKNVTFKWRNKPLFIRHRPAEEIAREEAVP LSDLRDQETDSQRVQKAEWLIVLGICTHLGCVPIANAGEYGGYYCPCHGSHYDASGRIRK GPAPTNLEIPPYVFTTETTVTIGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXX------------------------------------- -----------------------------------------EKRILQAISFPFTCKIRIX FKDNSYLYMVLEFVTGGEMFSHLRRIGRFSEPHXRFYAAQIVLMLEYLHHLDIMYRDLKP ENLLIDVLGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVY EMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRSLLQVDLTKRFGNLKNGVN DIK--------------------------------------------------------- -MYADTLLILFISVATAVFGEGLTWLLVYRTEKYKKLKAEVEKQSKKLEKQKEMVMDTTE RSHKKKLERQEERLKTNNRDLSMVKMKSMFATGFAFTALLSMFNSIFDGRTVAKLPFVPI SWLRSISHRNLRGEDYTDCSFIFLYILCTMSIRQNIQKLLGF------------------ ------------------------------------------------------------ -------------------------------------------LAERRGWGQFLFRPKPG EPQKDHKFYRRLYPQIISDIDRIENNWRTGHHTLQRIHCRSETSKGVYCLQYDDLKIVSG LRDNTIKIWDRGSLECVQVLTGHTGSVLCLQYDENIIVSGSSDSTVRVWSVKTGEMINTL IHHCEAVLHLRFCDGIMVTCSKDRSIAVWDMQSPTDINLRRVLVGHRAAVNVVDFDQKYI VSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACL RVLEGHEELVRCIRFDNKRIVSGAYDGRVKVWDLTAALDPRAPAGTLCLRTLVEHSGRVF RLQFDEFQIVSSSHDDTILIWDFLN------------LIGDSGVGKTCVLFRFSEDAFNS TFISTIGIDFKIRTIEMDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKS FENIQNWIRNIDEHASTDVE-----NKCDMNDRRQVSKERGEALAVEHGIKFVETSAKNS INVEEAFFTLARDIKAKMDRKL-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------MHKFTVDLPKKHGRGGQSALRFARLRLEKRHNYVRKVAEVAVTLFISNDRP NVAGLVLAGSADFKTELSQSDMFDPRLQAKILKIVDVSYGGENGFNQAIELASESLANVK FIQEKKLIGKYFDEISQDTGKYCFGVDDTLKALEMGSVEILIVWENLETMRYMLKNHQTD EEKILYLRPEQEKDKTHFTDKDTGVEMELVDSQPLLEWFANNYKTFGATLEIITDRSQEG AQFVRGFGGIGGILRYQVDFQMMEPLDDLEEDFDLDDYITRSSQPLVGKRCKDDEHFIQM IMDANAQSHKLYIMDARPSVNAVANKARVGGYESEDTYQNAELVFLDIHNIHVMRESLRK LKDVCFPTIDDAHWLSNIEATHWLDHIKQILAGAVRIADKVESNKTSVLVHCSDGWDRTA QLTALSLLMLDPYYRTIRGFEVLIEKEWVSFGHKFAQRVGHGEDKHSDADRSPVFLQFID CVWQVTKQFPNAFEFNEQFLMVILDHLYSCLFGTFLANCESQRFKEGVRDKTVSLWSYVN CQLEEFTNPLFQHVLFPVASLRRIELWTGYYVRWNSRMKPQEPLNMRNRELLQLKTQLQR RVDELSLELDAKN----------------------------------------------- ------------------------------------------------------------ ----XVEAVQLLGNKVIEELRLSDPHEVLQMLMNEGGCEISSADATVRMLITTIPPNLKK LDPEIHLDAKLMQQHLVSIRHTRWFEENASHSSIKVLIRLFQDLRSRFDGFLPLTAWIID LLAHYAIMVNPKREPLPLHVSFRRCLXLLSAGFFLPGSAGITDPCEQGSVRVHTIMTLDH RARLCYTAQTLLRVLSHGGYKQILGLEGNAGIATEMSVWEGVVVTPSDKAFEKAEK---- ------------------------------------------------------------ --------------------------------------------------TFVPTERRYP EGQSKERRRAAIAQALSGEVNVVPPSRLLALLGQALKWQQHQGLLPPGTTIDVFRGKAAV KEQEDEKYPTQLSKTIKFGQKAHIECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLK YQAQDNYMMMDDAVLCICFSRDSEMLATGGQDGKIKVWKIQTGQCLRR------------ -------QLLSASFDQTVRIHGLKSGKTLKEFRGHTSFVNDGIFAADGHHIISASSDGTI KIWNIKSTECQNTFKSLGGTTGSDITVYSVHPLPRNVEQFVVCNRSNTVVIMNMQG--VR SFSSGKREGGDFVCCTLSPRGEWIYCVGEDMVLYCFSITTGKLERTITVHEKDVIGTAHH PHQNLIATYSEDGLLKLWKPAQQ---KVPELMRCAEPRLKEFIKYARVELAPPADLPAIQ KGFSNLMTAKTKKWKAVTVKEGSLVAFEVLCWFFIGE----------------------- ------------------------------------------------------------ ----------------------------------------SMQFFNYVMRKVWLYQTRIG LALYDVAGLGYLKESDLENYILELIPTLPQLDGLEKSFYSFYVCTAVRKFFFFLDPLRTG KVKIQDILACSFLDDLIELRDEDLPKEMQESNWFSAPSALRVYGQYLNLDKDHNGMLSKE ELARYGTGTLTPVFLDRVFQECLTYDGEMDYKTYLDFVLALENRKEPQALQYLFRLLDVQ XKGFLNIFDINYFFRAIQEQMRSHGQDXVAFDDVKNEIFDMVKPTDP------------- -----------------------------FDIGDCFINLQPVGYGASGLVFAATDKRNDK RVAIKKVR-VSDQRCCRQALREIRILKRLEHDNVILVYEILGAKGLANSKSVYIVQELMD TNLHELMQHEQLKQEHIKLFLYQFLXGLKYIHSANVLHRDLKPTNLLVNDNLLLKIGDFG LARIIDPEYNHKGQLTQNVGTCWYKSPEMLLSSADYDSAADVWSAGCIFAEMLNGRPLFA GMRDLDQLRLIV------------------------------------------------ ------------------------------------------------------------ -----ELSPPKTTPEWVKFCKQLFGGFSTLLWIGAILCFIAYTIQSTKQEDTPGDNLYLG IVLTCVVIVTGCFAYYQEAKSSRIMDSFKNLIPQFALVLRNGDKLNLHAEELVVGDIIEV KFGDRVAADIRVISAHGFKVDNSSLTGESEPQSRSPECTSDNPLETKNLAFFSTNAVEGT CRGIVIATGDRTVMGRIANLASGLEVGKTPIAHEIEHFINIITGVAVFLGVSFFIIAIVL GYQWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTI CSDKTGTLTQNRMTVSHMWLDNNIMEADTSEEQTNASYDTTSATWQSLSTIAMLCNRAEF KVNQQNVPVLKRECNGDASESALLKCVELSIGNVTQFRALHKKACEIPFNSTNKYQVSVH PGDSIYLLVMKGAPERILDRCATIMINGKDEPMTQQWRDSFNQAYLDLGGLGERVLGFCD YNLPPDQFPAGYPFDSDAENFPLTGLRFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVT GDHPITARAIAKGVGIISEGNETVEDIAARLGVPVSKVNPRDAKACVVHGSDLRDMTPAQ IDEILFYHTEIVFARTSPQQKLIIVEGCQRQGQIVAVTGDGVNDSPALKKADIGVAMGIA GSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLVFILAD IPLPLGTITILCIDLGTDLVPAISLAYEQAESDIMKRQPRDPKHDKLVNDRLISMAYGQI GMIQASAGFFTYFVIMAENGFWPSRLLGLRKEWDSKSINDLEDSYGQEWTYAQRKVLEYT CHTAFFMAIVIVQWADLMICKTRRNSIIHQGMMNHHLTFGLFFETTLAAFLSYCPGLDKG LRMYPLHFTWWIVPMPFSLAIFIYDEVRKYQIRRSPGGWVERETYY-------------- ------------------------------------------------------------ ---------------EAEQITVIDGPDDEGKMFERPGKLSDYFPSPYANDEAAKAANNGA YPPDLTYIVSARHGGEDYIFSLLTSYCDPPAGIEMRDGLYYNPYFMGGAIAMAQSIFSEV VTYDDGTTPSASQLAKDVSSFLKFASEPEHDERKRMALKALLGFLFLTVYYYKRHKWASL KSRKIV---------------------------------------GGTPMVRLNRMSEET G--CEILAKVEYLNGGGSVKDRPALYLIREAVDSGKLRPGGTIVEGTAGNTGIGLAHMCN SMGFKCVXFMPNIMSQEKIDLLRTLGAEVFPVPV-VPWSDPANYNNQAAALAESMDNAYW THQFDNLANKRSHYETTGPEIWKDTNGTVDAIVLGTGTGGTLAGVSTYLKEQNPNIKAFL VDPPGSML---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------FIYPDGSKYEGSWVEDQRSGNGKYSYINGDYYDGEWQNHVRHGQGTYV YADTGSKYTGTWKDGKREGQGELIHANHKYVGPWKGDVMEGKSRYVFDIGCQQHGVYI-- -------------------------------------------VCKLDMHKKMVRRGYIA MLAIDNDVRRRGIGSHLVMKAIQAMVRDDCDEVVLETEVTNKAALRLYENLGFVHDKRLF RYYLNGVDALRLKLWLRSVESVMFYLPANTKRCLKEEIHKDVLVTGEYALSEGPGQKXNL RVTDAKGHILYNKEDASSGKFAFTTEEYDLFEVCFESKMVGGGRGAEREVSLRIKHGVEA KNYENLAKAEKLKPLEIELKKLEDLSQSIVNDFAYMRSREEDMRDTNESTHSRVLYFSIF SMCCLIGLATWQVLYLRRFFKAKKLIE--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------STRLITXPAEFQIDDTFSVPGVGTVVSGTTLRGLI RLNDTLLLGPDAVGQFLPIVIKSIHRKRMPVLEVRGGQTASFSLKKSQIRKGMMMLSPRL EPMACWEFEGEILVLHHPTTISVKYQAMVHVGSVRQTATIICMTKEHL------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------STQFNWD CSLVATGSMDKTCKLWDAATGQCIGTLSGHEDEVLDVTFDYTGQYLLTASADRLYSVATQ AKLEGHEGEISKVCFNPQGTRILTASSDKTARMWDVDSGQCSQILEGHTDEIFSCAFNYE GNTIITGSKDNTCRIWR------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------------SF HPCVRFKRWESEKILSFVPPDGSFRLVSYHIGAQYIAAIPVYIRHHISFRETGQGKLEIT VGPKQTMGKPVENVILEIPFSKSVLNVMLTVNQGKYSFDPVTKVMTWDVGRIDSTKLPNI HGSIKLQSGCPAPDSNPIISVQFSISQLAASGLKVNRLDMYGEKYKPFKGVKYLTKAGKF QVRTMATCEKPATRYGTSDWFTSNYAISTNAERQRGASHDIRQEALFLRNETDNKTKWDQ LDTNTRLSDRVDHIRQWKDILDRTLEKLDKEITDLSDAKDNLEVALENMNLPCHVNIENL TAREGRMDIDVVEDAVEDQLKKEQKVIEGIKQQLQQNIHQAFEQLCVLQEARQQVLADLQ DKNVALGIDVDQYNLTDESSDISFKPDATRVLKGSTTPQQWEDFSRYNHDRAVAEMSNSQ HLREAIFATLEQTANDLKSQDNATDYALRKRMHEMQMAIDELNWQKKQTEDEIADMETEI RRLVDAIRAKINPTKLAETRLENRTYRPNVELCRDNVQYGLTDEVKQLYTSKASLEEKLR QSQHALDGLEKKLHRINEDLHCKTNSLKLDEMCVQNRSKLERNMTLMGMTNLKDVLANMI PEFQKTVKDFRSKHGNTKVGEVTVDMMYGGMRGIKGLVTETSVLDPDEGIRFRGYSIPEC QKLLPKAAGGAEMLPEGLFWLLLTGDIPTDAQVKAISKEWANRADLPAHVVTMLKNFPST LHPMAQFSAAINACNHDSKFKQAYTEGVRKNVYWEYFYEDAMDLIAKLPTIAALVYRNTY KNSSSVCPIDTEKDWSFNFTQMLGYDDAQFTELIRLYLTIHSDHEGGNVSAHTCHLVASA LSDPYLSFGAAMNGLAGPLHGLANQEVLLWLDGCVWTEQDLKNYVWNTLKSGVVVPGYGH AVLRKTDPRYTCQREFALKQMPEDAGFKLVSAVYKVVPDILLEQGKAKNPWPNVDAHSGV LLQHYGMTERNFYTVLFGVSRALGCMASCIWDRALGLPLERPKSLSTEHLMKM--XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXDKLFVHRDTPDNNASLTFEFNADNKKRADLIIGHYPKGHQAAATIPLLDIA QRQNGWLPISAMNYVADLLKIPRIRIYEVATFYTMFNREPVGKYRVQVCSTTPCVLGGCG CDVIID------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------QNL LINKNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIF AELANAGRPLFPGNDVDDQLKRIFKLLGTPTEETWQGLTQLPEYKPYPVYNVQQQVVPNL STKGRDLLLSLLVCNPGRRISAEEXMQHAYFSDLNPAVK-ESKFFTYDGPKPKLTYPWKD VCDGWPLEYVEHHPNYEKAKEWMEKNLSDDLLELYL------------------------ ------------------------------------------GDKEDAESGDVKDDLFDI ITEKWSQIDEECIDDLGDMKR--------------------------------------- ------------------------------------------------------------ ---ILEEYMWHRKHTYMRLDGSSKLSDRRDMVADFQARTDIFVFLLSTRAGGLGINLTAA DTVIFYDSDWNPTVDQQAMDRAHRLGQTKQVTVYRLICXGTIEERILQRAKEKSEIQRMV ISGGNFRPDVLKPKEVVSLLLDDDDMERKMSLDTIPKDLRNLRACLLCSLIKTFDQFEYD GCENCEEYLHMKKNRDAVYECTSSSFDGMIAMMTPDDSWVAKWQRISRFTRGVYALSVTG RLPPGIVRELKAKG---------------------------------------------- ------------------------------------------------------------ ---IPGIKVDKGVVSLAGTDAESTTQGLDGLGERCKQYAKDGAKFAKWRCVLEXGPNXPS RLALIENATSLRRYACICQQ---------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------EEDPSGISEFWLTIFKNI DMLSDMVQEQDEPILKHLRDIRVKLSMGFTLEFYFDENEYFTNSMLTKEYIMRSEPDKDE PFGFEGPEIIKCKGCTIDWKKGKNVTVKVIKKMQKHKGRGTKRTVTKTVQNDSFFNFFTP PTVPEGEPDEETEALLAADFEIGHFIRERIVPRAVLYFTGEALDEDEEGDDEDGD----- --TDTSQGKPQXISNINACQAVVDAVRTTLGPRGMDKLIVDNNGKATISNDGATIMKLLD IVHPAAKTLVEIAKSQDAEVGDGTTSVVILAGEFLKQVKPFVEEGVHPQIIVRAFRKATN LAVQRIKDVAVHIPKDSKEQRSLLEKCASTALSSKLVAQHKEFFSKMVVDAVMMLDELLP LNMIGMKKVQGGALEDTQIVAGVAFKKTFSYAGFAMQPKKYQNTKIALLNIELELKAEKD NAEIRVDNVKEYQAVVDAEWTILYDKLEKIYKSGAKVVLSKLPIGDVATQYFADRDMFCA GRVPEEDLKRTLQACGGCIQSTVASLELGKCALFEEKQVGGERFNLFSGCPKARTCTIIM RGGAEQFIEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIAGKEQLL IGALAKALEVIPRQLCDNAGFDATNILNKLRQKHAGMWYGVDIVSEDITDNYVSCVWEPA IVKINAIIAASEAACLILSVDETIKNPKHVQEGAPPGRGRGRPMKRNNMVPNGHFHKDWQ RWVNTWFNQPARKTRRRNARVEKARKIAPRPVGGRLRPVVRCPTFKYNTKSRLGRGFTLE ELKAAGIAKRVAPTIGIAVDFRRKNRSIEGLQTNIQRLKEYKSKLILFPKKL-------- ------------------RQVPERRESDEVTDEERSYSAYTALRQARAHKRLLGARQKKA AEAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXLSCRFYEHKFPECEDVVVVTVTSIAEMGAYVHLLEYNNIEG MILLSELSRRRIRSINKLIRVGRDECVVVIRVDKDKGYIDLSKRRVSAEEVVKCEEKFAK GKCVNSILRHVGELLSYESDDQLEELYQKTAWYFDKKYGKAGSSYEAFK----------- ------------------------------------------------------------ ----------------------MARGQQKIQSQQKKAKAAEKAKMDQKKAGLAGLQYSCK VCMSKMPDPKTYKQHFENKHPKAELPPELKDI-------DMSRQGVTTVPKGHCAACTKP IVGQVITALGKIWHPEHFNCCHCKQELGTCNFFERDGRPYCETDYHNLFSPRCAHCQGPI LDKCVTALDLTWHPEHFFCAQCGRTFGEDGFHEKDGKAFCREDYFELFAPKCGGCCRPIM DNFISALGRQWHPECFVCQECHTVFGTGSFFDHEGMPYCETHYHARRGSLCAGCHKPITG RCITAMYKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCHPCFVKLFMRPLTAEETKLFFE KLSKYIGENIKLLIDRPDSTYCFRLHRDRVYYLSETLMKYASCVGKDELISFGTCFGKFT KTQKFRLHITALDFLAPYAKYKIWVKSSAEQQFLYGHHIMKSGLGRITEGTTQYQGVVVY SMSDLPLGFGVAAKSTQECRQADPMTIVCFHQADIGEFIRSEDTL--------------- ------------------------------------------------------------ -----------ILGHSERRHVFGENDALIGEKVKHALESGLSIIPCVGEKLEEREAKKTE DVVFRQMKAKDWTKVVIAYEPVWAIGTGKTATPEMAQEVHASIRKWLTDKVKPDVAKTVR ILYGGSVNAKNCKELAKQPDIDGFLVGGASLKPEFIDIINAK------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------LDIPRMLDAEDMVNSVKPDERSVMAYVSSYYHAFSG AQQAETAANRICKVLKVNQENERLMEEYERMASDLLEWIRRTTPWLENRTTDNTLPGTQQ KLEEFRDYRQRHKPPKLEEKAKLETTFNTLQTRLRLSNRPAYMPTEGKMVSDITNAWKGL ERAEKGFEEWLLSELQRLERLDHLAQKFRHKCDIHEEWTYGKEDLLQAQDFKQCRLNELK ALKKKHEAFESDLAAHQDRVEQIAAIAQELNALDYHDAASVNARCRRICDQWDLLGTLTQ QRSTALIEAEKILERIDQLHLEFAKRAAPFNNWMDGAKEDLVDMFIVHTTEEIQGLINAH EQFKQTLGEADKEFQAIIALVQEVSRLAQQYGISGVSENPYTTLSAQDITQKWRDVQRLV PIRDSSLQQEMAHQQNNERLRRQFAQKANLVGQWIERHLDAVASIGVQKGSLEDHLNKLK GVEKEVLSFKPNIDELEHYNQEVQEAMIFENKHTQYTMETLRVGWEQLLTSVARNINEVE NQILTRDSKGISNDQMDEFRKSFFHFDRNRTRRLEPKEFKACLVSLGYNIRDDRQGEADF QRIMSIVDPNNTGSVTFDSFLDFMTRETTDTDTAEQVMQSFRILAGDKPYITGDILRREL PPDQAEYCIQRMAPYGGHDAAPGALDYTSFSTALYGESDL-------------------- -------------------------------------------------KYTLQPVADEL PKLLGKPITFLKDCVGAEVEAACAKPNPGTVILLENLRFHVEEEGKGVGADGKKVKADDA AVKAFRESLSKLGDIYVNDAFGTAHRAHSSMVGCQLPQKASGFLLKKELEYFAKALDKPQ RPFLAILGGAKVADKILLIESLLDKVNEMIIGGGMAFTFLKVINNMEIANSLYD------ ------------------------------------------------------------ -------------------------GTKGMMDAVVAATEKGTISIAGGGDTATCCVKFKT EDKLSHISTGGGASLELLEGKTLPGVAALSDA-----------PNVTLETTMGSIVCELY WKXAPNTCRNFAELARRGYYNGVKFHRIIKDFMAQTGDPTATGRGGASIYGKEFDDEISN ELRHTGXGILSMANSGTNSNGSQFFITLAPTQWLDNKHTIFGRISVGMQVVKRIGLVDTD NDDRPVDDIRIM------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------VKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDQACAGLNNMQLG DKKLIVQRASVGAKGG-QMPVQIQIPGLNMNQVPTEVLCLMNMVTPEELEDEDEYEDILE DVKEECGKYGTVKSLEVPKPIKGIEVPGVGKIYVEFNSVIDCQKAQQALAGRKFSNRVVV TSYYDMDKYHRREFFVPMFDRVLIQRLAAETKTKGGVLIPEKAQSKVQSGTVIAVGSGVK TDEGKLIPNDVKVGDQVLLPEFGGTKIILEDQDYFLFREGDFLGKFERLKTQVPDIKTSL NIVQHLQSKKEDLKMHFQLSDNLYAKAKVPPTEKVCLWLGANVMLEYELDDAEKLLQKNA AIASLEQVDADLGFLRDQLTTIEVNMARVYNWDVKRRQAAKGMAEEALAKAGLHFDELNK IRVLEPEVAQQTGELKEECKDFLDKLSDFKKIVGTFIDVVDEVAGEVEREKMKAIGSRNL LKAISKQREAQQQQLMALIAEKKMQLERLRIQHDALQKEEQGQTEFIEQFILQK------ -------------------------------------------------VGKVRDVRLIT DNKTRRSKGIAYVEFAEVESVPLAMGLDGQRLLGVPIIVQASQAEKNRLGGNTGPMRLYV GSLHFNITEDMLRGIFEPFGKIEQVNLVLDLDTGRSKGFGFVTFRNAEDAKKALEQLNGF ELAGRPMKVGHVTERTGEMSMLDSDEMDRAGIDLGATGRLQLMAKLAEGTGFQIPPVAAN ALNLPNPIIAPPIATQCFMLSNMFDPTTTAPNWEVEIQDDVIDECNKHGGVLHIYVDKAS PQGNVYVKCLSIAAAAASVTALHGRYFAGKVITAAYVPLPNYHALFPDASRAVQLVMSSS ------------------------------------------------MAALSKAISKNV LFSHLDDNERSDIFDAMFPVHRHGGEVIIQQGHEGDNFYVLDQGEVDIYVNNDFVSRIGE GGSFGELALIHGTPRAATVKANTDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLSKVSIL ENLDKWERLTISDSLETVQFDDGQEIVRQGEPGEDFFIITEGSASVLQQ--QNEERVEVG KLGPSDYFGEIALLLDRPRAATVIARGPLKCVKLDRARFERLLGPCSDILKRNITQYNSF VSLSV------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------YDHCDFPNLISPNNVATYGALCALASFSRQELQKNVIASSP FKLFLELEPQLRDIIHQFYESKYASCLKLLKEIKDNLMLDLYLAPHVSTLYTQIRNRALC QYFSPYLSADMTKMAAAFNTTVSALEEELMQLILDGQINARIDSHNKILY-KDVDQRSAT YAKSLAMGEDFQRRTKALILRSAMLKNQIHVKSPPRDGSTGSEMSIAPASTASMAQRNEI MDTAEDFADQILRQSKHFLPHVARLCLVSTFLEDGFRMWFQWSEQREYINSTWGCGWFLA SAFVLINLLGQLSTCVMVLIRKHVSIACFMLFGVIALQTIAYSILWDVKFLMRNLALTGG VILLLAEIKAEGRSLFAGLPSLGENTPKTYLQLSGRVLLVLMFLTLLRFDFSFLQMLQNI IGTALILLIAVGYKTKLASLILVANLTILNIYFNAWWNIPSYRPMRDFLKYDFFQTMSVI GGLLLVVAIGPGGYSMDEHKKKWRHMVALLSGDGVGPEMLGHVKNVFSFINAPVDFEEVK LSRNHIALKGNVDTLFKMRNLALRTELDLFANVVWVKSFPGVKTRHTDIDLVVIRENTEG EYRQLEHEAVGGVVESLKIITEKNSTRIARYAFEFAQRNGRKKVTAVHKANIMKLSDGLF LECCHNVSEEYPDIEFEGMIVDNCSMQLVSRPHQFDVMVLPNLYGNIITSIGAGLIGGAG LVAGVNLGDRYAVFETGTRTTGHALVGKNIANPAALLLASSDMLEYLGLVPHA------- -------------------------------------IFDKTTRIVERILFEEDNPFVDY TGTDAESGLAEGDMLKLSRLFFDEHWSKHRTVTCMDWSTQYPELLVASYNNNAESPHEPD GVALVWNVKYKKTTPEFVFHCQSAVMSTCFAKFHPNLIIGGTYSGQIVLWDNRSNKRTPV QRTPLSAAAHTHPVYCVNVVGTQNAHNLISVSTDGKMCSWSLDMLSQPQDSMELQHKQSK VAVTSFSFLANDVNNFVVGSEEGAVYTACRHGSKAGITDMFEGHQGPVTGIDCNTVPGQI EFSPYFLTSSFDWTVKLWNIKENRPLHSFEDNSDYVYDLKWSPVHPALFASVNGMARIDL WNLNTDIEVPTASATNVALNKCSWHSSGQQIAVGDDHGHIHV-NVGELLAMPRNDEWTKF VHTLQEIKNNQADLDDEQMEDQLLQVTKIIESQVDAEIERMEKMDDGDFEGLRRNRMEQL KVAQKQKQEWLSLGHGQYQEIVDEKEFFEVSKKSANVVCHFYRESTFRCKIVDKHLALLA PKHIETRFVKIDAEKCPFLVERLRIVVLPTICVXKDGKTVDYIVGFD------------- ------------------------------------------------------------ ---------------------------------------------------FQVGDRVLC MSNMWTEYAVGIHALPEGMTFEEAAALQINYVTAYHMLFEFGNLRKGNKVLIHMAAGGVG IAATQLCRTVPDVIVFGTASAKHDAIKENGVDHPIDYRTQDYVEQVKNISPEGVDIVLDP LSGPDAAKGYNLLKPFGKIIHYGIANTVSGSTKSLWKMARTYFSVKNYSPLNIMGDNKAV CGYYMGAV-ALTVILDLYKEGKIKPKIDSVWAFEDISKAMGRLENRR-----------MS RKQTPSDFLKQIIGRPVVVKLNSGVDYRGVLACLDGYMNIALEQTEEYVNGQLKNKYGDA FIRGNNVLYISTQKRRVMSQNQGVLLLRRQLADLNKNPVEGFSAGLIDDEDIYRWEVLII GPPDTYYEGGFFKAHLTFPQDYPQKPPKMKFITEIWHPNIDKSGDVCISILHDPGEDKFG -ERPEERWLPIHTVETILVSVISMLADPNDESPANLDAAKEWREDKTEFKKKVARCVRKS QET------------------YVGECLPKYVQKVQVTTGDELEVLVHPDGVLPVLTFLRD HTNAQFTNFIDVCGVDMPTREFRFEVVYNLLSLRYNARIRIKTYTDELTPIDSCSDIYKG AIWFEREIWDMYGVFFSNHPDLRRILTDYGFEGHPFRKDFPLTGYVEMRYDD-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------NGHIVDIYSCALDQ TGLHEMKYLCNLTGGHMVMGDSFNTSLFKQTFQRVFSKDPKGEFKMAFSATVEVKTSREL KVQGCIGSCVSNNVGLSVSDTELGLGGTSQWKMCGLYPNTTYAFYFEVVNQHTAPIPQGG RGFVQFISQYQHSSGQRRIRVTTLARNWVDASINMQHIAAGYDQEASAVLMGRIAVFRAE TDDGPDVLRWLDRMLIRLCQKFGDYRKDNPTTFRFPEQFTLYPQFMFHLRRSQFLQVFNN SPDETSYYRHMLLVEDLTQCLIMIQP---------------------------------- --------ISQWRKAKYHELPEYENFKQLLQAPVDDAQEILQTRFPMPRYIDTEAGGSQA RFLLSKVNPSQTHNNMYNDAGGHVLTDDVSLQVFMEHLKKLAVSTASXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXTQAPAVIHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYR KKVQLDAEEVQIDILDDYAAIRDNYFRCGEGFLCVFSITEQESFQSTSEFREQILRVKND ENIPFLLVGNKMDLEDRRQVSVEEAQARAQEWNVSYVETSAKTRANVDKVFYDLMREIRA QKVAKKKSGRKCIIL--------------------------------------------- ----DILMYMDRVYVQQNGVENVYNLGLMIFRDQVVRNPVIRNHLRETLLEMVAKERRGE VVDRGSVKNACHMLMVLGLDSRNVYEEDFERPFLEQSADFYRVESQKFLAENSASVYIKK VEARINEEAERATHYLDKSTEEPMVKVLEEELISKHMKTIVEMENSGVVHMLKNNKTADL ACMYKLFIRVPNGLKTMYGCISSYLREQGRALVTEDEGNKNAIVYIQNLLSLKDRFDHFL HESFSDDRLFKQIISSDFEFFINLNTKSPEYLSLFIDDKLKKGVKGMSEQEIENVLDKSM VLFRFLEEKDVFERYYKQHLAKRLLLNRSVSDDSEKNMISKLKTECGCQFTSKVGGCTK- ------------------------------------------------------------ ---------------------------------------------QVSTFQMVILMLFNH KDKWTYEEVKTETDVPERDLMRAIQSLALGKMTQRVLTKEPKTKEIEPDHTFMVNDQFTS KLFRVKIQTVAAKGESEPERKETRSKVDEDRKHEIEAALVRIMKARKRMQHNILVAEVTE QLKSRFLPSPVVIKKRIEGLIEREYLARTPEDRKIYTYVADRIDIFPSRMAMAIMKTRLA GAQKGFSLLKKKSDALTSRFRSILKKIIETKMLMGDVMKEASFSLTEAKFAMGDFNHLVL QNVSKAQTKLKSRKDNVAGVNLPVFEHYTDGSDSYMLTGLSRGGQQIDRLKKNYAKAVEL LVELASLQTSFVTLDEVIKTTNRRVNAIEHVIIPRIERTLAYITTELDEREREEFFRLKK VQKKKKEVR---------------LRVLVTGAAGQIAYSLLYSIAKGDVFGPNTPISLVL LDIEAMMGVLKGVVMELIDCALPLLTEIIPTSDISMAFKDIDVGVLVGAMPRREGMERKD LLKANVKIFKQQGQALDQFAKKNVKVIVVGNPANTNAFICKKY-PSIPPQNFTCLTRLDQ NRAQSQIASRQDVINVIIWGNHSSTQFPDVTHATLVLEVVKDDNWIKNEFISTVQTRGAA VIAARKLSSAMSAAKA-------------------------------------------- -----------------------------------SSQSGVLMVGPNFRVGKKIGCGXFG ELRLGKNLYNNEHVAIKLEPMKSRAPQLHLEYRFYKQLGQAEGVPQVYYFGPCGKYNALV LELLGPSLEDLFDLCDRRFSLKTVLMVAVQLLHRMEYVHQKHLIYRDVKPENFLIGRQAN KKQHIIYIIDFGLAKEYIDPETHKHIPYREHKSLTGTARYMSIHTHLGKEQSRRDDLEAL GHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPVEVLCENFPDELAIYLRYVRRLD FFETPDYDYLRKIFIDLLARNGWESDWEFDWTGRQMRHGGSVQVLSSANGELGGNGGQSD TPITAPREVEVVSETK----------------------------YGLQFYMQYLAHWPEY FQVAESSQGHIMGYIMGKAEGHADNWHGHVTALSVAPEYRRLGLAAKLMNTLEDVSERKR CFFVDLFVRVSNQVAVDIYRKLGYTIYRVVLEYYAGEKDEDAYDMRKALSRDKDK----- -------------LDSALDLMRRLPPQQIEKNLADLIDLVPGLCEDLLSSVDQPLKIARD KNIGKDYLLCDYNRDGDSYRSPWSNQYEPPLEDGAMPSERLRKLEIEANAAFDQYRDMYF EGGVSSVYLWDLDHGFAGVILIKKAGDGSKKIRGCWDSIHVIEVQEKSSGRSAHYKLTST AMLWLQTNKEGSGTMNLGGSLTRQIESDAPVSDSSPHIANMGRMIEDMENKIRNTLNEIY FGKTKDVVNGLRSTMQLQRENLQNDLAQALRGRSSYEGDFDDVDEPLDEVNEHDQVEILP AGEQVDPQNRITTPYMTKYERARVLGTRALQIAMCAPVMVELEGETDPLQIAMKELKARK VPIIIRRYLPDGSFEDWGIEELIITDKRATFRDRIMAPAGDTAFTMGKGLVAGAAVLGLG SLCYYGVGLSSEVGAIDRAALWPAVVKERIRDTYLYFGSSLVFTAISRNPVMMNLMMRNS LLAIFGTMAAMIGSGMVCRSLPYKEGAKQVAWMVHSGIVGAVIAPLTLLGGPLLMRAACY TAGVVGGLSTLAVCAPSEKFLNMGG-LAMGLGVVFVSSIGTMFLPPSTALGAGMYSIAMY GGLVLFSMFLLYDTQKIVKRAETHPVYAVQPFDPINESVSIYMDTINIFIRIAMILAGGG NRKR-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------NPNKPDMIIKPASPLVCVEYNPKDAHILLGGQYN GQVGFWDTRKGSQPVEITPIEHSHRDPAYKTIWIQSKTGTECFSTSTDGRVLWWDIRKLG EPTESLYLDPTKKQDPTKAQGAMVLEYEPTIPTKFMVGTEQGSVISCNRKAKTPGEKIVA VYPGHHGPVYALQRNPFFVKNFLTVGDWTARIWSEDIRESSIMWTKYHQAYLTDGCWSPT RPAVFFTTKMDGTLDIWDYIFKQNDPILSLQVCDEALHSIRVQEHGRLIATGSHNGTTTL LELSESVYTMQRNEKALVTAMFERETRREKILDARHRELKLKERTRTSWEELVQRVTSIA KPLASRKXNKKLYKIIKKALRKGVREVQKFIRKGEKGLVVLAGDTNPIDVISHMPVVCED KSIPYCYAPSKEDLGAACGXHRPTCMVMVKQHDDYTVLYDECVDEV-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------LLDTVATFTSYELMDYKTFVTYTVFCGMIALDRQDIREKIVKGSEIL EVLHGLPDIKQFLFAFYNCQYADFFKMLATVETVMKYDMYLAPHYRFYVREMRIHAYSQL LESYRSLTLAYMAKAFGVTVDFIDQELSRFIAAGRIHCKIDKVGGIVETNRPDSKNWQYQ ETIKKGDILLNRLQKLSRVINICNGFRSSVETIRGVPYKDLVIGVPKETFKNERRVAIVP ATVQNLKKGFSVTVEESAGVLAKFGNDDYAAAGATVNAGDIYKSDIVLKVRAPTPAEVQQ LRDENTLISFLYPAQNKELIDLMAKRHSTVFAMDCVPRISRAQVFDALSSMANIAGYKAV IEAANHFGRFFTGQITAAGKVPPAKVLVIGGGVAGLSAVGTAKNMGAIVRCFDTREAVRE QVQSFGAEFLEVGIKESGEGGGGYAKVMSKEFIEAEMALFAKQCKEVDIIITTALIPGKP APKLISKAMIESMKPGSVVVDLASEAGGNIETTVPGQVTVHHDVTHIGYTDFPSRLPGQA STLYSNNISKLLLSFGYYVNLEDEVARGSIILNKGEMLWPAPKPPPRNYFKETLTDAFMY TAGLSGILGLGIASPNAAFTQMVTTFGLAGIVGYHTVWGVVPALHSPLMSVTNAISGITA VGGMLLMGGGYLPTDTQQTMAAVAAFISAINIGGGFTVTQRMLNMFRRPDDPPEYTKLYL IPALSFLGAYGLATTGDYPDIHHMAYLAAALCCIGSLTGLSAQSTCRLGNTLGMIGVSAG IAATLGMLKPSPELFAQMAACVGTGGAIGAVAAKRIEVTDLPQMVALFHSLVGAAAVITC IANYMTEFPHFATDPAANVIKTSLFLGTFIGGVTLTGSLVAFGKLQGMLKSDPLMLPGRH MLNGALALGNIGAMGYYMMGSELSGLGMLGTTTALSSVMGVTLTMAIGGADMPVVITVLN SYSGWALCAEGFMMDNNVMTIVGALIGSSGAILSYIMCKAMNRSLPNVILGGYGTSSYAG GPAQAITGTHKEVDVLNTVDLLEEAQNIMIVPGYGLCVAKAQYPIAELVDVLRSKGKTVR FGIHPVAGRMPGQLNVLLAEAGVPYDIVHEMEEINDDMPEVDLTLVIGANDTVNSAAEDD PNSIIAGMPVIRVWLSKEVIVMKRTLGVGYAAVDNPIFFKDNTSMLLGDAKKTCDALLNK VK------------------------ISQVLHIEEILLGWERNNVYQILDSRHQQFLTAK EETDCCTRQFLGNIRPFTINISDMQGGMPIQLTRDLHCQ-GCC----CLQEMDICCPPSY KVATIKEKLCTPRYEIFDAMYKIEGICCYIK--CC-ADVPFKITREDAGEVVKHWNG-CR EMCGQVNEFTVTYAQNETALNKAILLGSAFLIDFMYFEVKNNSVDPEVQQFLMMEQQKAQ FQSQVHRLVDTCWDRCIDKPRDKLDSRAETCLSNCVERFVDTSIQITGRFQQMLQRSVMS RSEGLVQRRNVTQEEADLDSKETRLTLMEEILLLGLKDREGYTSFWNDCISSGLRGCILI ELGLRNRVELEKTGMRRRSLLNRKVLCKSDAPTGDVLLDEALKHIKETQPPETVQSWIEY LSGETWNPLKLRYQLRNVRERLAKNLVEKGVCTTEKQNFLLFDMTTHPLVDSTVKAKLVV NVYTGXV----------------------------------------------------- ---------------------------------------------------VEKAFMKFC KNSKKGNNRLCYYVGGLEESATSIVGELAKPISWGMPSDKICYKLYVKDQQICDLKYEKM VDFATVNLKKLKVKDLKNILSDWDEQCRGCTEKSDFIKLIDELMPKYAPEAA-------- -----------------------SQPGVEHEARVPKKILKCRAVSRELNFTSKEQMERFR LEQKVLFRGKCLEEWYFEFGFVIPDSTNTWQSIIEAAPESQMMPANVLNGNVIIETTFYD GDLMVSTSKVRIFYVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------- -----------------------------GILPDHVPLLAVLKPGVITVHEDDATSKRFF VSSGSVTVNNDSS-------------------QEGLNRATAEVASDQAKAEALISLECYE ALQKAIE-QIFATELKSRLVETGRNREIIETGHGLEKKKRIAYITSELRLTEALQDPHVC EKILEYNVHAEREGSRRYAKRMSETMSTLHGLRNKGVKVELGIPE------SAEVTKMQR SCFQLAEDYEELIEDWYFHHQQDLMKFLCADKFLPDK---FTPTDVTNEADVKGALVTKT KFGRLDVVVNCAGIGIAVATLDVKHNLVHDLDEFMRIINVNTGGTFNVIRLAAQMMYQNE PNADGQRGVIVNTSSIAAFDGGRHGAAYSASKGAIVGMTLPIARDLAGIGIRVNTVAPGP FDTPLLTTLRSKVIDYLISSVPFPTRLGQPDEFGHIVQSIVENPYLNGEVIRLDGAIR-- ------------AKSQITQHYPIIDHTYDAVVVGAGGAGLRAAFGLASKGFKTACVTKLF PTRSHTIAAQGGINAALSSVDDDKWQYHFYDTVKGSDWLGDQNAIHYLCEEAPKAVLELE NYGMPFSRMPDGRIYQRAFGGQSLKYGEGGQAHRACAVADRTGHSMLHTLYGRSLFYDAD YFVEYFALDLIMNQGRCVGVMALSLEDGNLHRFNATNTIIATGGFGRTYFSCTGAHTCTG DGAGLVARAGLPLEDMEFIQFHPTGIYGAGCLITEGCRGEGGYLVNSEGERFMERYAPSA KDLASRDVVSRAMTMEMREGRGVGELKDHIYLQLSHLPPEQLFSKLPGISETAQVFAGVD VTRDPIPVLPTVHYNMGGIPCNYMGQVIEHNGKDVIVPGLFAAGEASCMSVHGANRLGAN SLLDLVIFGRAIANIIEEQHKPGEKVPDLPQNAGEMSVDHIETLLNNKGNMPTADLRLKL QKAMHENAAVFRDGPTLQTAVRKVKEIWPEIEIKLSDKGRVWNSDLVEALELQNLIINAM ATVTGAENRKESRGAHAREDFPKRIDEFDYSKPLDGQKKVPIEQHWRKHTMAYVNVESGD VKLDYRPVIDTVLDDTKVQSIPPKIRSY-------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------DALGIREKTLGPDHPAVAATLNNLAVLYGKR GKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVERYYKRALEIYV HRLGPDDPNVAKTKNNLASAYLKQGKYQQ------------------------------- -------LVRLAKAVKAKKMRLKPNTMSAPFKQMENINVFLNYCEAYGVPKTGLFQTVDL FEGRNMAQVLNCIQQLGTECQRNSFNGPTIGARPTE------------------------ ----GAVRHVADIRADDMDADGQGIIGLQMGNKGASQKGMSMGATRHVADIRADDMSQAG QGVINLQYGSTAGATQQGMSMGGRR----------------------------------- ------------------------------------------------------------ --------------------------------------------------------NI-- -----------------------------------------TLEEHTQRVTGIDWAAQSN RLVTCGADRNAYVWPTLVILRINRAATCVKWSPLENKFAVGSGARLISVCYFEEENNWWV SKHIKKPIRSTVTCIDWHPNNILLAAGSSDFKTRVFSAYIKEVEAKPDATCWGKKMTFNN VMAEFSNGGGWVHDVCFSSTGEKLLWVSHNSSISIINATLRTDFLPFITCLWLTENCFVV AGNDCCPMVYTCDGANATFSAKLDDTKFTAMDHFRSMDKLGSKLGTTHQNTITQTSVYKG TKANCSVFTTTAMDGQLVNWDIKKEIDGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGL GKSTLVNSMFITDLYNADYNGPSHRIKKTVQVDTTQVLLKEGGVQLKLTVVDTPGFGDAV DNSNCWQPVINYVESKYEQYLNAESRVNRNINSDERVHCCLYFIAPTGHGLKPLDIEFMK RLHDKVNIIPLIAKADTLTPDECREFKKTLLNEIARHKIKIYEFDDEEENRHQKKLKDRV PFAVVGSNTVVEAGGRKVRGRIYPWGVVEVENLEHNDFIALRNMLIRTHMQDLKDITNNV HYENFRYSRLAFLSKDPIAQMAEEKKDHVQKLKKMEAEMEQVFEMKVKEKMQKLKDSEVD LQRRMEQMKKSLEQQTKELDERRRAFEKERDSWEDIHKMSRRYDSRTTIFSPEGRLYQVE YAMEAIGHAGSCLGILASDGIVLAAEKRNTNKLLDEVSYSEKIYKLNEDMACSVAGITSD ANVLTNELRLIAQRHLLQYQEPMPCEQIVSALCDIKQAYTQFGGKRPFGVSLLYMGWDHH YGFQLYQSDPSGNYGGWKATCIGNNSSAALSMLKQEYKEGETSVKEALDLAVKVLSKTLD TTKLTPEKVEIATLMRENGITKLRILPAPELEKVIKKYEAEEAKAEAEKKKDLNEAWERL KQLSLQRQERLFGAHEIQHFNRDADETIAWIAEKNTTLSXNDYGRDLPXCAALQRKNDGV ERDLAPLEEKVKALGVEAXRLAQTHPEQAEEIAAKQSDITSNWQKLXKKAQERKKRLDDS YYLHRFLPDFRDLVSWVHDMNAIISADELAKDVAGAEALLERHQEHKGEIDAREDSFRTT AEAGQKLLVSDHYATNEVEEKLVTLANEKTSLFELWEERRILYEQCMDLQLFYRDTEQAD TWMTKQEVFLANEDLGDSLDNVEALIKKQEDFEKSLAAQEEKINALDEFATKLIESEHYA ADSVASRRNTLLQRRNALLEHSQARHLQLEESYKLQMFERDCDETKIWINEKLKAASDEG YLDPTNLQGKVQKHQNFEAEVTANQGRIENVTQTGEELIQSEHYAKELIRERLDEIQTLW QQLFAQTERKGSKLREASDQQQFNRNVEDFEIWLSEIEGQLMSEDYGKDLTSVQNLQKKH ALLEADVSSRQERIDGIVQACEAFVQSGHFDADNIKSKAEQVLERYQQLNEPIIARREKL NDALRLQQFFRDVEDEEDWIREKEPIAASTNRGRDLIGVQNLMKKHQALQAELTGHEARI TAVCEQGGEMVTDGHFAADDIQQKMKALQDRWNQLRDKAQQRKQDLEDSLQAQQYFADAN EAESWMREKEPIVGNTDYGKDEDSAEALLKKHEALMSDLEAYRSVVDNLRETAQACKQQE APMVDDIGKECVVALYDYTEKSPREVSMKKGDVLTLLNSSNKDWWKVEVNDRQGFVPAAY VKKIDSSLTASQSNLADEFTVSVREQQVESQYDNLMELGRQRRQKLEESCKAYQLVREAG ELAQWINDKETVALSEEVGGDLEQVEVIQRKFDDFQKDLKANETRLVELNSIAERLTAMG QTEAAEKIKIQIEDLNTRWAALQQVTVERAQTLGSAHEVQRYHRDAEETKDWIEEKDAAC KLEDYGHDLATVQRLQRKHEGLERDLAALGEKVKELDETANRLMQTHPDQAQSIYDHQKE INESWNALTSMADTRKAKLLDSYDLQRFFSDFRDLKSWIHSMMALVSSDELAKDVTGAEA LLERHQEHRMEIDARSGTFQAFETFGHQLLQNRHYASSEVKEKLQELADARXELESAWIA RXAKLDQCLELQLFNRDCEQAEXWMAAREVSLE--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------NAAAIEQRCGLLQENLDALRKAVDSRKARLVDNSAF LQFIWKTDVVESWIADKQTQVSSEEYGRDLSSVQIFITKEETFDAGLQAFEKEGIQTITT LKDQLVSSNHAQTPAIEKRYQDVITRWQKLLNDSDARKQCLLRLQEQYRQVEDLYLTFAK KASTFNSWFENAEEDLTDPVRCNSIEEIKSLREAHDQFKESLTAAQVDFNQLSQLDKQII SFNVGVNPYTWFTMQALEDTWKSLQKIIAQRDDELSREQDRQDENDVMRKQFAQAANAFH QWLTETRTSMMEGNGTLEEQLEATKGKAVDIRSQKSQLKYIEDLSAVMEERLILDNRYTE HSMVGLAQQWDQLNQLAMRMQHNLEQQIDACNKSGVSEDSLREFSMMFKHFDKDKSGRLD HQELKSCLRALGYDLPMVEEGQTDPEYEAILDAVDPNRDGFVTLQEYMAFMISRETENVQ SAQDVEAAFRALTSNERPYIQAQELYSNLTRQQADYCISRMRPFVDPKGRSIPDAYDYIN FTHELFINAIQCYQCDSNEDKSCPSHKPFDLYLNALVDCNSFEADTPGIFCMKITQQSPG WYGWKKITRRCGRRATGGVAWGCRWNYEENGVWKEVCYCEDKDGCNTSS----------- -------------------------------------LRFHLLQETLYLTIAIIDRFLQD EVSRSKLQLVGVTSMLIASKYEEMYAPEIADFVYITDNAYTKADIRRMEVTILRQLNFQL GRPLPLHFLRRNSKAGEVDANKHTLAKYLMELTIVDYDMVHMRPSEIAAAALCLSIALLG WSDTLVHYSKYEESHLKDIMRHMAHLATRKLTAIKTKYQSSKFMRISTIPELRSQQIIDL A----------------------------------IFHSLLTGTYAQRYGKDPPGSVSLG LRMEEMIFNMADTHLFFNDLEECDQVHIDDVSSDDNGQDLSNYNFATDGFHAAATNNLCL ATGVRGGVDWMRKLAFRYRRIKEIYSSYRNNVGGLLGPQKRELWLQLRSEIEALTDNWLT LALKSLSIINSRSTCVNVLVTTTQLVPALAKVLLYGLGGVFNIENVYSATKIGKESCFER IVSRFGRKCTYVVVGDGRDEEAAAKQMNWPSWTITNHSDLAALHHALDLAYL-SMLSISG NRQTGQSVRTQNVMAACAISNIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEH PAAKILVELAQLQDEEVGDGTTSVVIIAAELLKNADELVKCKIHPTSIISGFRLACKEAC KYIQENMTISTEDLGRECIINVAKTSMSSKIIGPDSAFFSNMVVDAATAVKTSDGKGGFR YPIKAVNILKAKGKSSRESMLVTGYALNCTVASQAMTKRILGAKIACLDFGLMKAKMKMG VQILLETPEKLDGIRQREMDITKERIKKILSVGANVILTTGGIDDLCLKYFVEAGAMAVR RCKKADLRRIAKATGGQLIVTMANLDGEETFEASLLGQAEEVVQERICDDELIFIKGPKA RSAASIILRGANDYMVDEMERSVHDALCVVKRVLESKTVVPGGGAVEAALSIYLENFATS LSSREQLAIAEYARSLLTIPKQLAVNAAKDSTDLVAKLRAYHNTSQMKLEHKELKWVGLD LYEGVVRDNKKAGVFEPAVSKIKSLKFATEAAITILRIDDMIKLQPEQ------------ -------------------------------------------VQLADASFPETDFEVVR GNTNVKWSRIAPGSNVSHIVVLRPLKSGYFNFTSADISYVASEQEPQLAYTSSPGEGGIM NFKDYDRKFSPHILDWAA------------------------------------------ ------------------------------------------------------------ ------------------------------------------RQYTSDYKLDTYLKIARL YLEDEDPVQAEAYINRASLLQSDSSNEELQIYYKVCYARVLDFRRKFIEAAQRYNELSYK TIVAEQERMTALRNAVICTILASA------------------------------------ -------------------------------EHNLLSASKLYNNISFEELGSLLEIPPSK AEKIASRMISEGRMNGCIDQIDCTVHFEAREALPNWDKQIQSLCFQANNIIEKIAVHVPE WMAKTMDETMTMKLTDALVKNFRVAKVFRENTDRINSIDFSANGETLISSSDDDSIVIYD CQNGTPKRTLNSKKYGVDLINYTHATNTAIHSSTKVDDTIRYLSLHDNKYIRYFQGHTKK VVTLHMSPIDDTFLSGSLDKSMRLWDLRSPNCQGLMHLPGRPVAAFDPEGLIFAAGINSE CLKLYDLRSFDKGPFTTFKLQQDKDCDWTGLKFSPDGKLILVSTNGQVIRLIDAFQGTPL QTFMGHAN---------------------------------------------------- ------------------------EYLIVETKGEKKNVGVIQLNRPKALKVICGGLMGEL GQVLDGMESDPNIGCIVLTGSGKAFAAGADIKEMEKKDFCDVYSCNFLSSWTRLADTRKP VIAAVNGFALGGGCELAMMCDIIYANEQAQFGQPEILLGTIPGAGGTQRXLRPIGKYKRT NTVV------AQDAEKAGLVSKVFPREQLLDEAIKTAEKIAGLSTIVVAMAKEAVNTSFE TTLREGLHFEKRIFHQTFATNDRKEGMCAFVEKREAKFTN >Sabellaria_alveolata MSDRKAVIKNADMSEEMQQDAVDCATQALEKYNIEKDIAAFIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSGLSTQIRQLQTSIARRDIDQAAKYIGAGAATV GAAGSGAGIGSIFGSLVVGYARNPSLKQQLFSYAILGFALSEAMGLICLMMAFLILFAFM SHYKEGGKAPAPVTHRIRITLTSRNVKSLEKVCADLIRGAKEKSLKVKGPVRMPTKVLKI TTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADMDQVN NYIEPAKQFMKDSLRLVNRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNIL VMAAQISKKRKFVSDGVFRAELNEFFTRELAEDGYSGVEVRVTPTRTEIIILATRTQSVL GEKGRRIRELTAVVQKRFNFPEGTVELYAEKVATRGLCAIAQAESLRYKLIGGLAVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPINDYINTAVRHVLLRQ GVLGIKVKIMLPWDATGKTGPKRPLPDHVSIVEPKDEEIPAAPYSEQKAAKMSKRGRGGS AGGKFRISVGLPVGAVMNCADNTGAKNLYIIAVAGIKGRLNRLPAAASGSSVLATVKKGK PELRKKVMPAVVIRQRKSIRRKDGVFIYFEDNAGVIVNNKGEMKGSAITGPVAKECADLW PRIASNAGSIRKQKAPKVSLGPQVLEGENVFGVAHIYASFNDTFVHVTDLSGKETMVRIT GGMKVKADRDEASPYAAMLAAQDVAERCKTLGITALHIKLRATGGNRTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRLMGKPRGLRTARKLRLHRRDQKWHDKD YKKSHLGTRWKANPFAGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP RDGCLNYIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLWALYKEKKERPRSEGV ATIRTRRYLTNRLLCRKQMIVDVLHPGRATVPKTEIRQKLASMYKTTSDTIFAFGFRTQF GGGKTTGFALIYDTLDYAKKFEPKYRLQRHGARKQRKERKNRQKKVRGTKKAKVGAMGRV PLVNSKTYTTPRRPFEKERLDQELVCIGKYGLRNKREVWRVKYTLAKIRKAARELLTLEE KDPRRLFEGNALLRRLVRVGVLDETKMKLDYVLGLKVEDFLERRLQTQVSKLGLAKSIHH ARVLIRQRHIRVRKQVVNVPSYVVRLDSQKHIDFALRSSYGGGRPGRVKRKNMRKAQGGG GG-----------------MRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVGEAREELMRMLAEDELRD AVLLVFANKQDLPNAMNAAEITDKLGLHSLRQRNWYIQATCATSGDGLYEGLDWLSNQLK NQKMPLAKDLLHPSLEDEKRKCKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCQTVLCQPTGGKARLTEGCSFRKKQHMVRVNVLADALQSICNAEKRGKRQVLIRPCSKV IVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVSIPDLEKWTTNL LPSRQFGYVVLTTSGGIMDHEEARRKHLGGKILGFFFMGRMHAPGKGISQSALPYRRSVP TWLKLSSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKAKGLAPD IPEDLYQLIKKAVNIRKHLERNRKDKDAKFRLILVESRIHRLARYYKTKKVLAPNWKYES SNAAALVAEVELPEIKLFGKWTSEDVHINDISLADYIAIKEKYAKYLPHSAGRYQVKRFR KAQCPIVERLTSSLMMHGRNNGKKLMAVRIVKHAFEIIFLLTGENPLQVLVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIMLLCTGAREAAFRNIKTIAECLADELINAAK GSSNSYAIKKKDELERVAKSNRMTEQMTLRGTLQGHGDWVTQIATTPQFPDVILSASRDK SLVLWKLTRDHSYGYPHKSLRGHSHFVSDVVMSSDGQFALSGSWDKSLRLWDLSTGQTTK RFDGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGQCKYTIEDGHSEWTSCVRFSPNT QNPIIVSCGWDKIVKVWNLTNCKLKTNHHGHSGYLNVVSLSPDGSLCASGGKDGQAMLWD LNEGKHLYTLDGGDMINAMTFSPNRYWLCAATGPSIKIWDLEGKIVVDELRPEVISQNAE PPQCISLAWSADGQTLFAGYTDKLIRVWQ------XXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXMSDEKKSGSEHINLKVTGQDGSVVHFKIKKNTPLRKLMA AYCERTGVKLESMRFRFDGQPINETDTPSVLEMEDGDSIDVFQQQTGG------------ ----------------EYKGYLVSVDGYMNLQLANTEEYIDGALAGNLGEVLIRCNNVLY IRGVEEEDEEGEMKDMSDAEGDDVP---VTGGPMDVNTALQEVLKTALIHDGLARGLHEC AKALDKRQAHMCILANNCDEPMYVKLVEALCSEHGINLIKVDDNKKLGEWSGLCKIDKEG KARKVVGCSCVVVKDYGKESQALDVLNEYFKSRK--AIRKKLVIVGDGACGKTCLLIVFS KDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSI DSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDNNTIRELAKMKQEPVRYDEGKG MAERINAFGYLECSAKTKEGVREVFE----------------MDDFQSSEETAFVVDEVS NIIKESIEGAIGGNAYQHNKVNQWTSNVVEQCLNQLTKLGKPF----------------- -----------------------------------MFTAQAKIVKPQGEEPDEFEQTISK ALLELEMNSDLKQQLRELYITGAREVDVQNKKAIIIFVPVPQLRAYQSIQTRLVRELEKK FSGKHVVFIAKRRILPKPTRKTRRANKQKRPRSRTLTAVHDSILEDLVFPAEIVGKRIRI KLDGSRLIKVHLNKTSQTNIEHKVDTFTAVYKKLTGKDVNFEFPEYVLSRGGFRGGFGGR GRGRGRGRGRDKGGEKEWTPVTKLGRLVKDGLIKSLEEIYLFSLPIKEFEVIDFFIGPSL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDYNGHIGLGVKCSKEVATAIRGAIILAKLSV VPVRRGYWGNKIGKPHTVPTKVTGKCGSVVVRLIPAPRGTGIVSAPVPKKLLTMAGIDDC YTSARGQTATLGNFAKATYAAISQTYSYLTPDLWKETVFSKTPYQEFSDYLMKMSGNLDV LALKEDDVTKFLACGTHLGSTNVDFQMEQYVYKRKPDGVYILNLRKTWEKLLLAARAIAA IENPADVCVISARPYGQRAVLKFASYVGATAIAGRFTPGTFTNQIQAAFREPRLLVVTDP RIDHQPVTEASYVNIPVIALCNTDSPLRYVDIGIPCNNKNTNSIGLMWWMLAREVLRLRG TISREVPWDVMVDLFFYRDPEEAEKE---------------------------------- -------MKFNKMVTSSRRKNRKRHFNAPSHLRRKIMSSPLNKELRQKYGVKSIPIRKDD EVQVVRGNFKGQQFGKVVQVYRKKFVVHIERIQREKANGTSVHVGIHPSNLVIVKLKMDK DRKSILERKAKARQLGKHTEESI-SASATSVGGTVRQRKTASSGASSAGVWRFYTEDSPG IKVGPVPVLVMSVLFIGSVFMLHMWGKYTR-----KKKSVTNDVVTREYTVNVHKRIHGI GFKKRAPRAIKEIRKFAEKMMGTPDVRIDTRLNKHMWSQGVRNVPYRVRVRLARKRNEDE DSVHRLYTLVTYVPVTTFKGSQTVNVESXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNPEKLKQRIGGKGTARRKKKVVHRTATTD DKKLQSSLKKLGVNNIPGIEEVNMIKDNGEVIHFNNPKVQASLQANTFAINGHAEDKKIT EMLPGILNQLGAESIQNLKKLATATGDIDEDDEEFPDLVENFDEASKGEMTRYSVDPDSN TKSAKARGSHLRVHFKNTHEVASHIKQMHLRRAVKFLKNVIEKKEIVPFTRYLSGIGSKA QAKNWNANVGRWPKKSAEFLLQLLKNAESNAEFKGLASDQLVIDHIQVNRAPKMRRRTYR AHGRINPYMSSPCHIEVILSEREQVVSKPTK-----------------KKTGPKPELTEE QKQEIREAFDLFDAEGTGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGTIDFND FLTMMTQKMSEKDSKEEILKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQE---D GDGEINEPEFLRIMKKTSLYMGISRDKWHKRRKTGGRMAPLRKKRKFELGRPAANTRIGP QRIHTVRTRGGNKKYRALRLDHGNFAWGSEAQTRKTRVIDVVYNASNNELVRTKTLVKNA IITIDATPFRQWFEAHYATPLGRKKG-KGQEVDDAALKERSKKTQKKYTERKKDAKVDHA LEEQFSSGKILACVASRPGQCGRCDGYILEGKELEFYLRKIKAKKGKMALVVPEKFQHIL RVMNTNIDGRRKIAFAMTAIKGVGRRYSHVVCKKADVDTSKRAGELSEEEVEKIITIMTN PRQYKIPDWFLNRQKDIKDGKFSQVMSNTLDNKLREDLERMKKIRAHRGLRHFWGLRVRG QHTKTTGRRGRTVGVSKKKDSGTDSDSDDGPPDLE-MAAAAGLPEEMVSKAKQSRSEKKA RKAMSKLGLKQVAGVTRVTIRKSKNILFVINRPDVYKSPASDTYIVFGEAKIEDLSQQAT IAAADKFKADEEVDETGIEAKDIELVMSQASVSRSKAVKALKNNANDIVNAIMMGRVRTK TVKKAARLIIEKYYTRLTMDFHTNKRLCEEIAIIPSKKLRNKVAGFVTHLMKRIQRGPVR GISIKLQEEERERRDNYVPEVSAIEEVDPDTKEMLKLLDMANIPGLQITQPVTQSMKWQY KEEHPFEKRRAEGEKIRRKYPDRVPVIVEKAPKARVGDLDKKKYLVPSDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGALYQEHHEEDFFLYIAYSDESVYGMRELRITKL CLNICVGESGDRLTRAAKVLEQLTGQQPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAE EILEKGLKVREYELRRNNFSATGNFGFGIQEHIDLGIKYDPGIGIYGMDFYVVLGRPGFN VSKRRRKTSTIGFQHRVTKDESMKWFQQKYDGVILPGK----------PFCALLPEVQKP ERKIQFREKVLWTAVTLFIFLVCCQFPLFGIMSSDSADPFYWLRVILASNRGTLMELGIS PIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMVITVSQAIVYVMTGMYGEPAE LGAGICLLIILQLFVAGLVVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSP---- ------------------------------------------------------------ ------------------------------------------SQMLAAKFSGNFIVNLLG VWADVGGGGPARSYPIGGLCYYLSPPETFAHVVEDPIHAVLYIVFMLGSCAFFSKTWIDV SGSSAKDVAKQLKEQQMVMRGHRDKSMIHELNRYIPTAAAFGGLCIGALSVLADFMGAIG SGTGILLAVTIIYQYFEIFVKEQSE---------QNERAFQKQPTVFLNKKKAIIPRLSR NIGLGFKTPREAIDGAYIDKKCPFTGNVHIRGRILSGVITKMKMQRTIVIRRDYLHYIRK YNRFEKRHKNISAHLSPCFRDVKPGDVVTIGECRPLSKTVKFNVVKVTKGSGSKKGFDKF MVNVPKARKTFCKNSDCRKHTLHKVTQYKKGKDSIYAQGKRRYDRKQSGYGGQTKPVFHK KAKTTKKITLKMECTECKHRKQLSIKRCKHFELGGDKKKKGQMIMFMGRVIRSQRKGAGS IFRCHNKHRKGAAKLRPVDYAERHGYIKGVVKDILHDPGRGAPLAKVVFRDPYKYRLKTE TFVATEGLYTGQFVYCGKKATLQIGNILPVGSMPEGTIVCCLEEKAGDRGRLARASGNYA TVISHNPDTNRSRVKLPSGSKKVIPSANRAIVGIVAGGGRIDKPILKAGRAYHKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGHASTVRRDTSAGRKVGLIAARRTGRLRGSKQITG KAKRTKKVGITGKYGTRYGASLRKLVKKMEVTQHGKYTCSFCGKEAMRRKAAGIWNXKSC RKVVAGGAYVYSTTAAATVRSAVRRIREMKEMGRRPARCYRYCKNKPYPKSRFCRGVPDP KIRIYDLGRKKARVDDFSLCVHLVSDEYEQLSSEALEAARICANKYLVKYCGKDSFHMRV RLHPFHVVRINKMLSCAGADRLQTGMRGAFGKPQGTVARVQIGQTILSVRSRENLQGHVI EALRRAKFKFPGRQKIYVSRKWGFTKWDKTVYEGMRADGRLVPDGVNVQYKPNHGPLQAW RDAQKVTKVLGRTGSQGQCTQVRVEFIDDSARSIIRNVKGPVREGDILTLLESEREARRL RMTKGTSSFGKRHNKTHTICRRCGGRCYHIQKKTCSRCGYPAATMRKYNWSDKAKRRRTQ GVGRMRHMKKVFRKFRNGFREGTVAKKRSA------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------QLVMEGYNWCHERNVVTIFSAPNYCYRC GNQAAIMELDDALKYSFLQFDPAPRRGEPHVTRRTPDYFLMGAYKYMTELFRKKQSESLA FLLRVRAWQYRQLSSVHRASKPTRPDKARRLGYKAKQGVCVYRVRVRRGGRKRPVPKGAT YGKPTNQGVNQLKFQRSLQNVAEERAGRKCKALRVLNSYWVAQDSTYKFFEIVMVDPHNK TVRRDPKLNWICEAGKKHRELRGLTSAGRKSRGLGKGHLFTKTQGGSRHANWKKHNRMAA RRKR-------------------------------------------------------- ----------------------------------------EEKDWRPAVTIKQILLGIQE LLNEPNPKDPAQAEAYTIYCQNKAEYERRVKEQAMRFRDPSM------------------ -------------DKHMNLILGDCDEFRKVRPKKGEKREEKRVLGLVLLRGENLVSMTVE GPPPADEGVARVPLPGAAGGPGVGRAAGRGI----------------------------- ------------------------------------------------------------ ---------------------------------------------DLVRVCENIPIVLCG NKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLTGDPNLEFVASPA LAPPEVVMDPEM------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------RKIEFPAPNEEARADILKIHSRKMNLTRG INLRKIAEMMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFELAVAKIMQKDSEKNMSI KKLWKLSFAENFGLSGAAAIISKTAAAPIERVKLLVQNQDEMIKQGRLDRPYSGVMDCTA RTFQTEGLLPFWRGNLANCIRYFPTQALNFAFKDKIKQLFKMSKTDSYSVKFSKNIASGG AAGAMSLCFVYSLDYARTRLANDAKGAAKREFNGLVDVYRKTLKSDGFVGLYRGFVISCV GIIVYRGCYFGFYDTLKPIMLGEDAGVMLSFCLGYFVTITSGLISYPIDTIRRRMMMTSG QAVKYKGSIDCAVTVVKSEGFMSLMKGAGANILRGVAGAGVLAGFDKFQEVYITWRL--- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------LSPDIKTLDQIRTIERN QEIPHKGAFCDLVWSDPEDVDTWALSPRGAGWLFGAKVTNEFVNINNLKLICRAHQLVHE GYKYMFEEKLVTVWS--------------------------------------------- XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- ------------------------------------------------------------ ---------DMLKNAPMFKKVGAGRGKSAILRAAARGRGRGGRGMGRGGMQNEAGDYVDM YIPRKCSASNRIINAKDHASIQLNFAEVDDTTGRMTGAYKTYAICGTIRRMGESDDCLIR LAKKDSIIAKMVRGPRKHLKRLNAPKHWMLDKLGGVFAPRPSTGPHKLRECLPLMVFLRN RLKYALTYQEVKKIVNQRLIKVDGKVRTDKCYPAGFMDVITIDKTGDNFRLIYDVKGRFT VHRITKEEAQYKLCRVKMVGTGPKGVPYCVTHDARTIRYHDPLVKPNDTVQVXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXX-------------------------------------- ------------------------------------------------------------ -VEDPVSLEYITRFIARLKQKYTQSTGRRPFGLSALIIGFDGTAHLYQTDPSGTYHEWKA NAIGRSAKTVREFLEKHYTDETVSDKETIKLCLKALLEVVQSGSKNMEVAVMRNGQPLES LKSEEIEEYIKEIEAEKEEEAEKKKQKGGGSGGDKKDDKDKKKKYEPPIPTRVGKRKKKI KGPDA------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------IIEAGTL NKKSPPAIRKVYDQMPEPRWVISMGSCANGGGYYHYSYSVVRGCDRIIPVDIYVPGCPPS AEALLYGILQLQKKIKRMKTVQMWYRKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMVAQKKSKK ALESINSRLALVMKSGKYVLGYKQTLKTLRGGKAKLVIIANNTPPLRKSEIEYYAMLAKT GVHHYNGNNIELGTACGKYFRVTTLSITDPGDSDIIRNMPS-XXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKIELCS FSGFKIYPGHGKRVVKIDGRSFTFINSKCEAAHHMKRNPRKINWTVLYRRKHKKGAQEEV TKKRTRRVAKFQRAITGATLNDILAKKNQKPEVRKAQREQAIRAAKEKQRAKDGAKPRVG GKRMKLNISYPATGAQKLVEIDDEKQLRSFYEKRMSAEVPIDCLGDEWKGYVARISGGND KQGFPMKQGILSPYRVRLLLTKGHSCYRPRRSGERKRKSVRGCIVDANLSVLNLVVLKKG EQDIPGLTDTTIPRRLGPKRASKIRKLFNLSKEDDVRQYVVRRPLQQRSKAPKIQRLVTP VVLQRKRRRAATKRKRVSKKRDEAAEYAKLLAQRIKEAKERKLERRRSASHSKKVKAKEL RGKKKEDLNSQLKDLKTELSQLRVAKVTGGAASKLSKIRMVRKSIARVLTVINQTQKENL RKFYKPKDLRHKKTRAMRRALTKHERSIKTSKQLTRQRVYPMRKFAVK------------ ------------------------------------TETYKGSKFHRVIKDFMIQGGDFT RGDGTGGKSIYFDDENFKLKHYGAGWMSMANAGKNTNGSQFFITTKKTEWLDGRHVVFGK ILEGMDVVRKIENTKTKGDKPERDVVIADSGSIEVTEPFAVEKKPSAEKKKKVTKSFMVD CTHPVEDGIMDCANFEKFLQEKVKVNGKTGQLKTKVVVRSDIDFSKRYLKYLTKKYLKKN DLRDWLRVVASTKDAYELRYFQINNEDEEDDDNE------EEENKYGGCEGVDAMYVKLI SCDGHEFIVKREHALTSGTIKAMLSGPGQFEENDTNEIRFRQIPSHVLQKVYTYLTNK-- ------------------------------------AELGEHRDAKSLWLAIHDKVYDIT KFLEEHPGGEEVLLEQGGGYGTESFEDVGHSTDARELMEQYLIGEVAEPDRSSWTSWLIP LGIAIATALIYRFVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------ ------------------------------------------------------------ ----------------------ITMLQADEKPDVKYSDIGGYDIQKQEVREAVELPLTHF ELYKQIGIDPPRGVLMFGPPGCGKTMVAKAVAHHTTAAFFRVVGSE-------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------AHAPLSLETI RERVLLVLKLYDKIDPEKLSLDSHFMNDLGLDSLDQVEVIMAMEDEFGFEIPDGDAERLM KPADVVQYIADKEDV--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------VEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKM REANFTVSSMHGDMPQKERDTLMKGFRAGQTRVLITTDVWARGLDVQQVSLVINYDLPNN RELYIHRIGRSGRFGRKGVAINFVKNDDIRILRE-------------------------- -----------------------------------------------HFQYVAAVPRIGV GMDSCVTPLRHGGLSLVQTTDFFYPLVDDPYMMGKIACANVLSDLYAMGVTECDNMLMLL AVSQKMTEKERDVVVPLMISGFRDTAEEGGTSVNGGQTVINPWMTVGGVATTVCQPNEFI MPDNAVVGDVLVLTKPLGTQVAVNAYQWLDQPDRWNRIKLVVSEDDVRKAYQRAMFSMAR LNRTAARLMHKYNAHGATDVTGFGLLGHANNLARIQKNEVGFVIHNLPIIAKMAAVSKAC GNMFGLLQGHSAETSGGLLIALPREQAAAFCKDIEKQEGYQSWIIGIVEKGNRSARIIDK PRVIEVPAKEKDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXTVPFDARFPNQNQTRNCWQNFVDYHRCHKIEDYE PCDYFKRVFTALCPNEWSSRWQEQVENGTFAGKIXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGKEKVHINIVVI GHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITI DIALWKFETEKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKNGQT REHALLAYTLGVKQLIIGVNKMDNTEPPYSEARFKEIQKEVSSYIKKIGYNPDLVPFVPI SGWHGDNMLNMGWYKGWSAQTGKTLLNALDNIQPPSRPTDKALRLPLQDVYKIGGIGTVP VGRVETGKLKPGMVVTFAPAAISTEVKSVEMHHTALEEALPGDNVGFNIKNVSVKDIRRG NVCGDSKNDPPKEAANFTAQVIILNHPGQIAAGYAPVLDCHTAHIACKFSELKEKIDRRS AKKLEDNPKFVKSGDAAIVLMLPQKPMCVEPFQQYAPLGRFAVRDMRQTVAVGVIKAVEK KE-GNVKATKAAQKA--------------------------------------------- ------------------------------------------------------------ ---------------------------------------------------TSSGDMTCA LWDIGTGQQTTSFTGHTGDVMSLSLSPDMRTFVSGACDASAKLWDIRDGMCKQTFSGHES DINAITFFPNGYAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLG GYDDFNCNVWDTLKQDRAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKIWNXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPKE IKEIKDFLLTARRKDAKSVRIKKNVKFKVRCSRYLYTLVIQDREKADKLKQSLPPGLQVK ELQMSKISRDTLIDAVDAVFDKKRKFTESVELQISLKNYDPQKDKRFSGTIKLKHIPKPK MKVCVLGDQQHCDEAKANDVSSMDAEALKKLNKNKKLVKKLAKRYDAFLASDSLIKQIPR LLGPGLNKAGKFPTMLTHSDSMTGKIDDVKATIKFQMKKVLCLAVCIGHINMSREEIAQN ITLAINFLVSLLKKNWQNVRSLYIKSTMGPAQRIY------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------AIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADR------------------------ ------------------------------------------------------------ ---------------LPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPF ICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDEL PAEFKLYLPIQNK---SNIQNLQDPFAEDE-IHIRIQQRNGRKTLTTVQGISSEYDLKKI AKACKKEFACNGTVVEHPEYGEVIQMQGDQRNKINEFLQQVGLSDRIKVHGFXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXTGRITAALARQLPRAAKQKKALGAGFVATRNITTTAEVSTILEDRILGTAGAELEET GKVLSIGDGIARVYGLKNIQAEEMVEFSSGLKGMALNLEPDNVGIVVFGNDKLIKEGDIV KRTGAIVDVPVGEQLLGRVVDALGNPIDGKGPVD-GSRARVGVKAPGIIPRISVKEPMQT GIKAVDSLVPIGRGQRELIIGDRQTGKTAVAIDTIINQKRFNAGKDEKAKLYCIYVAIGQ KRSTVAQIVKRLTDAGAIDYTIIVSATASDAAPLQYLAPYSGCAMGEFFRDNGKHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNNDFGGGSLTALPVIE TQAGDVSAYIPTNVISITDGQIFLETELFFKGIRPAINVG-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------YRVNGQYIMEGLASSFLFSIGGLGFVILDQTNTPTTPKFNRILL LCVAFSSILVSFFMSRVFMRMKLP------------------------------------ --------------RIHHQKSRYIYDLFYKRKAISRELYEYCLKENIADKNLIAKWKKQG YENLCCLRCIQTRDTNFATNCICRVPKAKLEEGKIVECVHCGCRGCSGEYAQVTKMLGNG RLEAMCFDGVKRLCHIRGKLRKKVWINQSDIILIGLRDYQDNKADVILKYTSDEARSLKS YGELPENAKINEEGEDIITFEDIDDI---------------------------------- -----------KNRDPVQLDSLSIRGNNIRYFILPDSLPLDTLLIDDTPRAKMRK---QK PTSEMTPEELAAREQEEFNTGPLSILTQSVKGNTQVLINCRNNKKLLGRVKAFDRHCNMV LENVKEMWTEVPKTGKGKKKSKPVNKDRYISKMFLRGDSVILVLKNPLPIVIDARGHLLG RLAALVSKTILQGQRVVIVRCEGINISGSFYRNKLKYLSFLRKRMNTNPRRGPYHFRAPS KIFWRTCRGMLPHKLSRGKLALDRLKVFEGVPPQYEKTKRVVVPSALKVLRLKSRRRFCD LGRLAHEVGWKYQGVISTMEARRKVKSAQFYHKKKADIKLREQAKKAAPQQQIIESYG-A GDAEKGKKVFVQRCAQCHVVEAGGKHKTGPCLNGIFGRKTGQAKGFSYTDANKNKGITWS KDTLWVYLENPKKYIPGTKMVFAGLKKKSDRADLIAYLEQYTK---------------AE EIEDIVLRSGFTVLQKRRVCLTPEQASDFYAEHYGKLFFPSLVTYMSSGPIIAMVLSREK AISYWRELIGPTNTVKARVTHPDCLRAIYGTDDQRNGLHGSDSYTSAEREIRFFFSDSTT EPIPMGQVARDYLAKSVNPTLLKGLTELCKQKPVDPVIWLADWLLENNPNKPKI------ ------------------------------------------------------------ -----NLSSMSKILKCASNDDAITVKAGDNADTVTFMFESPNGDKVSDYEMKLLDIDSEH LGIPDTEYSAVIKLPA-------------------------------------------- ------------------------------------------------------------ ----------------KSLSAYHTSKSEITGRVVAVIGAVVDVQFDGRPPPILNALEVQG RTSRLVLEVAQHLGENTVRTIAMDGTEGLVRGQECVDTGLPISIPVGKETLGRIINVIGE PIDERGPINAKHSASIHADAPEFVDMSVEQEILVTGIKVVDLLAPYARGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIEGGVISLKDDTSKVSLVYG QMNEPPGARARVALTGLTVAEYFRDAEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFGHLDATTVLSRGIS ELGIYPAVDPLDSNSRILDPNVVGEEHYTVARGTQKILQDYKSLQDIIAILGMDELSEED KLTVARARKIQKFLSQPFQVAEVFTGSPGKLVPLKETIKAFKAILAGEYDHLPEVAFYMV GPIEEVVEKAERLAE--MLMPKKNRVAIYEHLFKEGVLVAKKDFNAAKHPELEVPNLHVI KALTSLKSRGYVLEQFAWRHYYWRLTNEGIQYLRDFLHLPPEIVPATLKRQSDGGDRAAY RRGGDSEKKGDVGAGTTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX MTNTKGYRRGTRYMFSRDFRKRGVIPLSTYFKTYKRGDIVDIKGNGAVQKGMPFKAYHGR TGRIFNVTQHAVGVIVNKRVGGKILPKRINVRIEHVKHSNCRLEFLNRVKQNEVVKKEAR ENYTVKRQVKQPSKAHFVRTKYNKPQVLEPIPYEFIAASRSHWVQVSPEDPKMEWKDITD RAANAAFAIELFKGLGITFSQILKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAICPAQAITIEAETRDDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEY STETHEELLYNKEKLLENGDKWEPEIAQNLVADHLYRMATQAKVAKTDGENNHNADKEQQ EAIEQIDEVQNEIDRLNEQASEEILKVEQKYNKLRQPYFSKRSDLIAKIPNFWVTAFVNH PQVSALLNEEDEEALQYLTKVDVVEFEDIKSGYKINFYFDDNPYFKNSVISKEFHLNSSK STPIEWNSGKDLTNKSKKRSHEEQESFFSWFADHGDAGADELGEVIKDDIWPNPLQYYLA SEIEEEAPDEEGEEGEEKKLTKQEELLLQDFSRNVSTKSSALFYGNAFIVSAIPLWLFWR IHQMDPTILFAAMTLVSTYLVS---------------------------------KKMTK QEKDERILWKKNEVADYEATTYSIFYNNALYLFIIVLASFYLLRSFGPTFNYTLSVGLAG GLLALFSTSTKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------- ----------------------------------------------NSIEKIMEVDSHIG CSMSGLIADSRTMIDRARVEAQNHWFTYNEKMTVEGVTQAVSNLALSFGDYD---GVMSR PFGVALLFAGVDEKGPQLFHVDPSGTFI--DAKAIGSGSEGAQQSLQEVYYKSMTLAEAK KEALKILKQVMEEKLDATNVELATVTPGDLFQMASKDDLETVIKDIXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDVDTELLDYEEEEQEEAKDVKGTYVSIHSS GFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVICQAKSGMGKTAVFVLSTLQ QIEPVDGQVSVIALCHTRELAFQISKEYERFSKYMSGVKIAVFFGGMSIKKDEQVLKSNC PHIIVGTPGRILALAKTLNLKHVKHFILDECDKMLEALDMRRDVQEIFRMTPHEKQVMMF SATLSKDVRPVCKMFMQDPMEVYVDDDSKLTLHGLQ---------EKNRKLFELLDALEF NQVIIFVKSVQRCMALAQLLIDQNFPAIAIHRAMTQEERLSRYQQFKDFQKRMLVATNLF GRGMDIERVNIVFNYDMPE---------------------------------PPSYGDLG KSARDLFNKGYNYGFYKLEAKTKSANGVEFTTNGGSNHDSGKFNGSLETKYKWSDYGLTF QEKWNTDNTLGTEITIEDQLVKGLKLAFDTQFAPQTGKKSGKIKTSYKQDYVNLNCDVDF DFAGPTIHGAAVAGYNGWLAGYQMSFDKSKLSRSNFAVGYKTKDFTLNTSVNDGSEFSGS VYQRVNSELETGVQLNWAAGSNATRFGLAAKYQCAKDSSFRAKVNNSSQIGLAYQQKIRD GVTLTLSSLLEGKNFNAGGHKVGLGIDFEA------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------TEAGMFAIRAERDYIIEEDLMKAVRKVGENKKLESKLDYKPIMTDN LSTVVTKFYREYMSSTPSKIKLVDAYLFYILLTGAIQFLYCCLVGTFPFNSFLSGFISCV GSFVLGVCLRVQVNPANKIEFHGISPERAFADFIFAHVIFHLVIMNFIGXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXMGRFMKQGKVVLVLAGRYAGRKAVIVKNYDEGATDRQYGHALVA GIDRYPRKVTKKMGKKKIKQRSKVKTFVKMVNFNHLMPTRYSVVNLEKNVVNKDAFRDPS LRRKAKREIKSRFEERYKTGKNRWFFQKLRFERTFIMIKPDGVQRGLVGDIVNRFEKRGY KLVAMKFKQFDEAHLKQHYIDLADKPFYPKLCKFMSSGPVVPMVWEGDVVKMGRMMLGAT NPLQSNPGTIRGDFCIDLGRNICHGSDSVESANKEIDLWFGKDEVQNWNVCTADNVYEKS APKPVKTVTKAKDKALKAKKNVTKGKYDKRQRKVRTSVHFRRPKTLKLARAPKYPRKSIP HRNRLDQFKIIKYPLTTESAMKKIEDNNTLVFIVDKRANKPEIKRAINQMYEMNVAKVNT LIRPDGEKKAYVRLAPDYDALDVANKIGIIMPAKQRMRIANEKMAKNVTQRGNVPKTLKP DENEYPVGPWLLGLFIFVVCGS-----------XXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXQPTIFSKIVDKSIKADIIFEDDKCLAFRDVNPQAPVHFLVIPK TPLPALQDDQSLLGHLMLV----------------------------------------- -XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXRLYIKAVFTGYKRGLRNQHENTALLRIDGVTTKDETDFYLGKKCAYVYKA KRRTACPGNEKSSRIRVIWGKVTRPHGNSGGVRAKFRKNLPPCAMGKRIRVMLYXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------- ------------------------------------------------------------ ------------------------------------------------------------ --------RRKAWKRMVTKACYVGEGFTRKPPKFERFIRPMALRYKKAHVTHPELKATFC LPIIGVKKNPSSPLYTTLGVITKGTVVEVNISELGLVTQSGKVVWGKYAQVTNNPENDGC INAVLLVMSARPLITVYTDKGAASERNVTLPAVFRAPIRPDIVTQVHSDISKNHRQPYAV SVKAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRR VNVNQKRYALCSAIAATGIPSLVMSKGHRIEQTPEVPLVLDDKVQEVKKTKEAVGILKKL KAWSDIEKVKSSRRFRAGKGKMRNRRRVQRRGPLVIYDQDNGINQAFRNIPGVTLINVNR LNLIKMAPGGHVGRFCIWTESAFKKLDSIYGTWRKASTEKNNFNLPMPKMTNTDLSRLLK SDEIQNAIRAPQKSHGRRILKKNPLKNWRVMQRLNPYAVVQKKSAQQKEERQRKIDAKRG ITTVDSGGKARPR----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------- --------------------------------------AAKMIKDTMDKKFGASWHAAVG EGLGFEVTHEVKNLLYMYFGGTMAIILWKCSMSHRKFSAPRHGSLAFLPKKRSVRHRGKV KAFPKDDVSKPVHLTAFLGYKAGMTHIVREVDRPGSKVHKKEIVEATTIIETPPMVVVGI VGYIETPRGLRTFKTVWAEHLSEECRRRFYKNWYKSKKKAFSKASKKWQDKDGVQEINSD LGKMKKYCKVIRVICHTQMKLMKKRQKKAHIMEIQVNGGTIPQKIEWARRHLEKKIPIKQ VFAEDEMIDIIGVTKGKGFKGVTSRWHTKKLPRKTHKGLRKVACIGAWHPARVSFSVARA GQKGYHHRTEINKKIYRIADGVHTKDGKVVKNNASTSYDITEKTITPMGGFPHYGEVNND FIMIKGCCAGPKKRVLTLRKSLLVHTKRVALEKINLKFIDTSSKFGHGRFQTPAEKTNVL GPLKKDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXX------------------------------------------ --------------SLPSKKKKVDSDRDYTYDELLKRVFDIMREKNPEMVAGEKKRIVMK PPQVMRVGTKKSSFSNFAEICKLLHRQPKHLLAFLLAELGTSGSIDGNNQLIIKGRFQQK QIESVLRRYIKEYVTCHTCRSPDTILQKDTRLYFLQCETCGSRCSVQSIKSGFQAVTGKR AALRAKT-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMPAPSKARVYADVNSLRQREYWDYESHVVEWGKQDDYQIVRKLGRGKYSEVFEAVNI TNNEHCVIKILKPVKKKKIKREIKILENLRGGTNIITLMSIVKDPVSR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------QVPETLLKKRKQRSEKSQEKKREIFKRAE KYVKEYRVKERDEIRRDRQARKTGNFYVPAEANLAFVVRTRGINGIHPRPRKVMQLFRLR QINNGAFVKLNKATINMLRLAEPYLTWGYPNLKSVRELIYKRGYGKVDGRRTALTDNAII EQRLGRYGIICIEDLIHEIYTVGPHFKEANNFLWPFKLNTPNGGWRRKNNHFVDGGDFGN REDKVNGLLKRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXMAVRYEMAVGLVKGHKTTVQKPRPSRRKGQQSKHTKYIRDIVR EVAGFAPYEKRIMELLRISKDKRALKFAKRRLGGHLRAKRKREELQNAIQQMRKAXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------KAVCVEAGMIALRREATELYHEDYMDAILEVQAKKKANLNYYAXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXX------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------NDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGKVACVAGYGDV GKGCAQALRAFGARVIVTEIDPINALQAAMEGYEVSTIEEALKEARIFVTTTGCKDIITG KHFGNMLEDTIVCNIGHFDCELDVKWLNDNCTKKDTVKPQVERYTLPNGRHLILLAEGRL VNLGCAMGHPSFVMSNSFTNQVLAQIELWTKAEKYTVGVHFLPKKLDEEVAAAHLDHLGV KLTKLSSDQAGYLGIPQEGPFKPEHYRYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXX----------------------------------------------------- ----------------------------------------EICVNTLKRDWKDDYGIKHI LLTVKCLLIVPNPESALNEEAGKLLLEQYDDYSKRARIFTEVHANP-------------- ------------------------------------------------------------ -----------------------ELGKGWAPTLIGYSMQGLCKFGFYEVFKIFYGNAIGE ENAFLWRTSLYLAASASAEFFADIALCPMEAVKVRIQTSEGWASTLREGVPKMRAEEGMY GFYKGLVPLWGRQIPYTMMKFACFERTVEAIYKYIVPKPRAECSKSEQLVVTFASGYIAG VFCAIVSHPADVIVSKLNKEKGSTFGEQAKKLGFMGMWQGLVPRIIMIGTLTALQWFIYD SVKVFFRLPRPPPPEMPESLKKKLEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ SLFAERNDLQYAVPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPDIYIELEISYFLLR RLLGVRTEGDRKGAKVQKLSKNEILMVNIGSLSSGGRVLAVKADLAKIGLSHPVCTEVGE NIALSRRVEKHWRLIGWGQIRRGVTVNPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--- ----------------------------------------------------------KD DPPPPEDDENKEKRTDDISSWDTEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMI KGKTP-------------------------------NKRLTKGGKKGQKKKIVDPFTKKD WYDVKAPSMFNIRQVGKTLVTRTQGTKIASEGLKGRVFEVALADLQNDEIAFRKFKLIAE EVQGRNVLTNFHGMNLTTDKLRSMVKKWQTLIEANVDVKTTDGFLLRMFVIGFTKKRTNQ IKKTCYAQSHQIRMIRKKMTDIMTREVSSNDLKEVVNKLIPDSIAKDIEKACQGIFPLHD VCVRKVKILKKPKFDVGKLMELHGETSSSATGEEGESVPRPDNYEPPV----XXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPNLPPISADKL KSKSEIRKVAVPNNRYTPLKENWARIFTPIVEHLHLQVRFNLKTRNVEIKTCKDTQDIGA LQKATDFVTAFTQGFEVDDALALVRLDDLFLESFDVTDVKPLKGDHLARAIGRVAGKGGK TKFTIENVTKTRIVLANSKIHLLGSFQNIKIARTAICNLILGSPPSKVYGNMRSVAARSS ER---------------------------------------------------------- -----------------------------------------------FREPIICKTIPRL VPGWTQSIVIGRHAHGDQYKATDFVAKGSGKFEMVYTPTDGGEQRWEVFNFKD-GGVGMG MYNTDESITGFAHSCMQYALKKKWPLYMSTKNTILKRYDGRFKDIFQEVYEAEYVKEFES AGIWYEHRLIDDMVAQALKSNGGFVWACKN------------------------------ -----------------------------------------------NPELARFCQVLEK SCVDVIDGGKMTKDLAGCIYGLKNVKPEQYLYTDDFLEAIREDLEXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--NLKTDAGLKALNEYLADK SYIEGYVPSQADAVVFAALSGPKATFVNALRWWNQINSY--DRSALPGVKKPIDSYGPAG ADDDDDDDDVDLFGSEAEKLKQARLDAYAAKKNPVLIAKSNIILDVKPWDDETDMAELEK NVRTIETDGLLWGASKLVPLAYGIKKLQICCVVEDDKVGTDFLEENICAFEDFVQSVDVA AFNKIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------LKEIVKSSLQSLQQRTWLI HWSLFVFFNHQKGRDLIIDMFLYNQDYLNAIQTMCPHILRYLTTAVITNKTVLKDLVKII QQESYTYRDPITEFLECLYVNFDFDGAQQKLRECETLLANDFFLVACLDDFIENS----- -------------LLAEKLNMNPDEAERWIVNLIRNARLDAKIDSKLGHVVMGTQAVNAY QQVIEKTKGLAFRSQMLAMNIEK------MGVSVETITPGDGKTFPQPGQTVIVHYTGTL TNGQKFDSSRDRGKPFEFKIGVGQVIKGWDEGVMQMSVGQRAKLTCTPDYAYGAAGAGGV IPPNATLNFDVELFGMKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXX----------------------------------- ------------------------------------------------------------ -----------------------------------TKKVHVIFNYKGKNLLIKKDIRCKD DVFSHLYTLIVRPDNTYEVKIDNKKVESGSLEEDWDFLAPKKIKDPEAKKPEDWDDREKI DDPEDTKPEDFDKPEHIPDPDAKKPDDWDDEMDGEWEPPMIDNPEYKGEWKPKQIDNPNY KGKWIHPEIDNPEYEADENLYSYKDTGAIGFDLWQVKSGTIFDNILITDDEGYAEQVGDD TWGKTKDAEKKMKDEQDEVERKQREEEEAKRKEEEGDEEEPMDDXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------- -----------------------------------------------------------K GFDYKTCNVLSALEEQSPDIAAGVHVGRDEEDIGAGDQGLMFGYATDETEECMPLTVVLS HKLNAKMSELRRNGGLPWARPDSKTQVTCEYKLDNGACIPQRVHTVVISVQHSEDVTLEQ LREDLMEKVVKTVIPSKYLDEKTIYHLQPSGRFVIGGPQSDAGLTGRKIIVDTYGGWGAH GGGAFSGKDFSKVDRSAAYAARWVAKSLVKAGLCRRVLVQLSYAIGVAEPLAIFVDSYGT ANMDDAHLLTVVKKNFDLRPGKIVKDLDLKRPIYQRTASYGHFGRPDFPWEQEKKLQIXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXMGIDICHKHDRKVLRKAPKSQDIYLRLLVKLYRFLARRTNA KFNKIILKRLFMSKTNRPPLSISRLVRHMKKAGRDNKTAVVVGTVTDDVRILDIPKMKVC ALHVTERARARIIKAGGEITTFDQLALTAPKGKGTVLLQGPRKAREAYRHFGAAPGVPHS STKPYVRSRGRKFERARGRRKSRGYKNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------- ----------------------------------AKTGTDIATQILEGDLFDFDVEVKPI LEVLVGKTVEQALLEVCEEEELANLRSQQRAFEELRNAELVEQQRLEEQERRHREEKERR MKQQKEILRKERETKDKISARAFAQSYLADLIPSV------------------------- ------------------------------------MRARGDFKEYRVVGRRLPSEKNRT PPLYQLRLFAPDKVTAKARYWYHVSQLRKMKKGSGEILSCKQVFEKKPTSIKNFGIWLRY VSRSGIHNMYREYRDLTTSSAVTQCYRDMGARHRARPSSIQIIRVEVIPSSKCKRPGIKQ FHDSKIRFPLPHRVSKRLHAPRFTTQRPKTFF---------------------------- ----------------------------APGDFTGYVQFIKDLQLPTAFLFGCKTIAAFP LVYHYINGIRHLTWDAGKGLKLPTQYKTGSAILASASYWXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMKIFKDIVSGDEMFSDTYPGAIWKVKGRDESAFGFNKSTVVDIVDGSKKEYMQHLKE YFKSVKGFQFFVGHALCRWETPEFFFFKHGLEEEK-XXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------PLNSVD LGRVVEEWRDLTSPENDSEKENKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSD PYVKLSLMLNGKRIKKKKTTIKKCTLNPYYNES--------------------------- ---------------------------------------------XXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXX--------------------------------------------------- ------------------------------------------------------------ ------------------------FVVSGTCTEQMYGMCESLWEPDLAPDDLFETISQAL MNSVDRDAVSGWGGVVYIIEKDKVTVKHLKSRMD-------------------------- ------------------------------------------------------------ -------------------------------------------------ARDKWLAPGGL IFPDRATLYVCAIEDRSYKDEKIQWWDRVYGFDMSCVKEVAVTEPIVDVVDPGQVVTNAC LVKEVDIYTVKEGDLSFSSPFTLTCRRNDYVHALVTYFNMEFTKCHKLHGF--------- ---------TVKKGEELYGTFAVKPNQNNQRDLDFEINVEYEGKLSSLKENNKYKMRMVK EDKGTWKSNYFMRIIQLLDEYPKLFVVGADNVGSKQMQQIRIALRVLMGKNTMMRKAIRG HLDANPALEKLLPHIKGNIGFVFTKSDLSDVRDKLINNKVAAPAKAGAIAPLDVVIPAQN TGLGPEKTSFFQALSIPTKISRGTIEIISDVPLIHTGDKVGASEATLLNMLGISPFSYGL QIQQVYDSGTVFSPAILDITDEDIRAKFMQGVANIASVSLAIGY--------SIINGFKN LLAIAAATDITFKEAETVKESAAKGKLIAVIGDEDTCTGFLLGGIGELDKSRNPNFLVVD KNTSIGEIDETFKKFT-------------------------------------------- -------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAVMVKKDVGGEKNGGKR TVRVSRMPRYYPTEDGPRKLASAFSQHKRKIRSSITPGTVLIMVAGRQKGKRVVFLKQLA SGLLLVTGPYQVNGCPLRRVNQIYVIATKTKVDVSGVQVPDRVNDAYFKRTKLRKPKHTE GEIFDKKKEEYTVSAERKEDQVSVDKALLQAISKNTDKKALLQYLASRFSLRNHQYPHKM VFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---CCFCLGTCEKNRD-GEAEALIS CAECGNSGHPSCLKFSPLLTERVKKMWWQCIECKTCSLCGESGKE--------------- --------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------AETCSPFTVLPGLMNEYRVPELNVQNGVLKSLSFMFEYIGEMSKDYIYAVCP LLEDALMDRDLVHRQTAMSSIQHLALGVYGFGCEDALTHLLNHVWPNVFETSPHVVQA-- ------------------------------------------------------------ -------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGASCTYPQQCSALRKNGFVVIKGHACK IVDMSTSKTGKHGHAKVHLVGIEVFTGKKYEDVCPSTHNMDVPNVTRKEYEVLDMTDGFL SLMDDSGDIREDLGLDACVWKALLDEKVKEFKITKXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXKVEAKKQVNPLFEKRPKNFRIGQDIQPKRDLSRFVRWPKY IRLQRQRAILYQRLKVPPPINQFTKALDRQTASQLFRLLDKYRPESKQEKAARLKARAEE RTKGKADAPTKRPPVVRSGVNTVTTLVEQKKAQLVIIAHDVDPIEIVLFMPALCRKMGVP YCIVLGRVVRRRTVTCLALTTVNSEDRSSLSKLVDSVKTNFNDRVDEIRRHWGGGVMGAK SLAAVAKLEKAKAKELAQRMRYVAAYMLAVLGGNASPSDADIKKILSSVGIEADDACIKK VISELKGKDMEEVLAEGKEKLASMPAGGGGAA------------------A--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------VQLV GDDLLVTNPKRVRDAIEKKACNALLLKVNQIGSVTESIEACKMSQDAGWGVMVSHRSGET EDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQ--------------------------- ------------------------------------------------------------ -----------------------------------KHALSSRIHTVMCTTLKVLQHLVVS ADMVGEALVPYYRQILPVLNIFKNKNLNSGDGIDYSQQKRENIGDLIQETLEAFERHGGD DAFINIKYMVPTYESCMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX--------------------------------TGLTAGQHGFH IHEFGDNTNGCTSAGSHYNPDGVDHAGPDDATRHVGDLGNVSAGKINITDKIVKLTGERS VIGRTFVVHEGVDDLGKGGHELSKTTGNAGGRAACGVIGISKMVNFTVDEIREIMDKKKN IRNMSVIAHVDHGKSTLTDSLVSKAGIIAGAKAGETRFTDTRKDEQERCITIKSTGISLY YTLQEKDSCDSFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQA IGERIRPVLFMNKMDLALLTLQLESEDMYLTFRRIVENVNVIIATYAQEDSPMGDIMVDP TKGTVGMGAALHGWGFTLKQFAELYSAKFKIEAPKLMKRLWGDQFYNYVRGFTQYILDPI LLVFKTTMSKENALKVCEKIGIKLTADEKEAEGKVLLKTIMRKWLPAGDALLQMISIHLP SPVTAQKYRVELLYEGPIDDDVGAAAKNCDPKGPLMMYISKMVPTNDKGRFYAFGRVFAG TCGTGMKVRIMGPNYTPVKNIQRTILMMGRYTEPIEDVPCGNICGLVGVDQFLVKTGTIT TYEKAHNMKVMKFSVSPVVRVAVECKNPADLPKLVEGLKRLAKSDPMVQCSIEESGEHII AGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETVAERSTQTCLSKSPNKHNRLFMSA EPMPDGLAEDIDKGDVSTRQEFKERARYLADTYDYDVTEARKIWCFGPEGTGPNIVVDCT KGVQYLNEIKDSVVAGFQWATKEGVLCEENMRGVRFNIHDVTLHADAIHRGGGQIIPTAR RCLYASVLTAEPKLLEPVYLVEIQCPQTVLGSIHGVMSTKRGHVTEQINVPGTPMWAVKA YLPVNESFGFTAALRAATGGQAFPQCVFDHWQLLIVADTRKRKSLNEAIPSLDKFLDKMX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------EIVLVGGSTRIPKVQQLVKEFFGGKEPSRGINPDEAVAYGAAV QGGVLSGEEDTGDLVLLDVNPLTMGIETVGGVMTKLIARNTVIPTKKSQIFSTAADNQPT VTIQVFEGERPMTKDNHLLGKFDLTGIPPAPRGVPQIEVTFEIDVNGILKVTAEDKGTGS KEHIVINNDQNRLSPEDIERMINDAEKFADEDKVLKERVESRNELESYAYSLKNQIGDKE KLGGKLSDDDKDTIEKAVEEQIEWLESNQEADTE-----KKSLEEIVQPIMSKLYADAPP PEGFEEKDELXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXX-----------------------------------ILKEEEGRKRVKLLTKQLQDV KKEKEVEIQQRNEMIAHLKDQLQEMKAKTNMEGKYIKKCSEVGVSQTQKRCNMGEKELRD EIETLKEKIDEENRVNAEIESYLRTHTERLQKLVDHWMEKYDKDVEAKQKELDILRASEA KDIERLQELTKLYAEYEQVVVEDR-----------------KSAVRMQSWWRGVMVRKGL GPYGKKKKKK-------------------------------------MVYMFKYDSTHGR YKGEVKLVVDGKVINVFMSMDPSKIPWADSGAEYVVESTGVFTTLEKANAHVKGGAKKVI ISAPSADAPMFVMGVNNTGYSKDMNIISNASCTTNCLAPLAKVINDEFGIVEGLMTTVHA FTATQKTVDGPSAKAWRDGRTASQNIIPASTGAAKAVGKVIPALNGKLTGMAFRVPVPDV SVVDLTCRIEKGASYDDIKAAVKGPMKGFLAYTDEQVVSSDFIGEPASSIFDARAGIALN NNFVKLISWYDNEYGYSNRVVDLIKYIYGVD----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------LRRFGRFDREVDIGIPDATGRLEVLRIHTKNMKLSDDVDLE QVAKETHGHVGADLAALCSEAALQQIREKMDLIDLEDDQIDAEVLDSLAVTQENFTWALG KSNPSALRETTVEVPSVSWDDVGGLENVKKELQELVQYPVEHPDKFLKFGMTPSKGVLFY GPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFD ELDSIAKARGGSVGDGGGAADRVINQLLTEMDGMGSKKNVFIIGATNRP----------- ---------------------------------------------------EICQRACKL AIREAIEEDIRRERQRADNPDDFDPVPEIRKDHFEESMKFARRSVSDNDIKKYEMFAATL KQSLGLGGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------CHTIMNCTKTCPKGLNPGAAVAELKKIMMGQESHGIPRQXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------LEAALKVVRKGWVESVIIGVAAAGQEIATRPFQL VTGRVWKGTAFGGWKSRDSVPKLVDEFMKGELKVKEFVSHTMPLDQINEGFDLMHSGKSX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------IRSIIALHNLISNKIANRDAE KNEGKPKEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------L ISQCTPPISFPSEQRATLSTRIQNAGTEVVEAKAGAGSATLSMAYAGARFANSILEALHG EDDIVECAFVRSDETESKYFATPVLLGKSGLEKNLGLGKMIDFEVSLIKEAMPELKTNIE KGEEFVAKN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------GAAQFMKERLFEISDPYRVHVCNLCGLIAIANLRNNTFEC RGCKNKTQISQVRMPYACKL----------------XXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------QDPESRISIRASDKRIACDEEFSDSEDEGEGGRRNRESHKRKRPXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXETNEEFDNRYETYFNRPDIDGWEIRKAMNDL QGYDLVPEPRIINAAMKACRRVNDYALAVRILEAVKEKCGPKVNEIWPYIVQEIRPTLTE LGINTPEELGYDKPELGCEDVYDM-------------EEVSKFLEGCNVIGGKEGIHFTY VRDGRPSGEAYIELGNEEDLEKALSKNKQHMGRRYIEVFRSKRSEMEWVVKRSGPEQDAV VRLRGLPFGCSKEEIAHFFTGLEIVPNGITLIHDAQGRTTGDAYCQFASMDIAEQAMSKH KERIGHRYIEIFKSSMMEARNDYDSQTGHCVHMRGLPFAATEQDILDFFKPMNPVNVVIH YNSGRASGEADVDFATHEESKEAMHKDRATMQHRYIELF--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------ERQYI LNIVKQIKKAGCTVLLIQKSILRDAINDLALHFLAKMKIMVIKDIEREDIEFVCKTLGCR PVASLDHFQPDTLGTAEMVEEVQTGESKVVKITGIANPGRTVSVLVRGSNKLVLEEADRS IHDALCVIRCLVKKRALIAGGGAPEIELSLRLREHSNTLSGMEQYCFRAFADALEVVPFT LAENAGLNPIATVTELRNRHAQGEITTGINVRKGAITNILEENVVQPLLVSTSAVCLASE TVRSILKIDDIVNCQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------- -------------------------------EWIQGEIKASGLRGRGGAGFPTGMKWSFM NKPDDGRPKYLVVNADEGEPGTCKDREIMRHDPHKLVEGCLVAGAAMGARAAYIYIRGEF YNEA-------------------------------------------------------- ------------------------------------------------------------ --------------------------------ESCGQCTPCREGVGWMNKVMQRWVTGNA RTSEIDMLWEMSKQIEGHTICALGDGAAWPVQGLIRHFRPELEKRFTDYHA--XXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XMSADLQWMVIRNNSAFLMKGNTFSREPNNLKNRHSFRYNGLVNQKTVGVEPCADGKGVV FVTRKSWRKPAKNFNRVELKKGGRATLATIKKMTKGSRYRKDLKMAAIRRASAILKSQKP VVPVKTR----------------------------------------------------- ----------------------------------------------DLALPKEQFDDLVR IGSFSGNVEWLKFFALGCSALGQSITDAMKTVCEILTADPDGGPARIPFQLFKDLYKYLG QIDGDITEEHMTAVLHYLQNHVDKQDGFVQPRNFLGPDSPSLSXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------KIVA IYPGHHGPVYSLQRNPFFPKNFLSVGDWTARIWSEDIRESSIMWTKYHMSYLTDGCWSPI RPAVFYTTKMDGTL---------------------------------------------- -------------------------------------------------DELVKRVGPIA NPLASRKLTKKIYKVVKKAVRSGVRIVQKYIRKGEKGLVVFAGDVSPIDVMSHL------ -----------------------------------------------------XXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLARNSARLAA-QQQR GYADMAFTFASPANVNIKQVDVPSFSGDFGILPDHVPLLAVLKPGVVAVTEEDGTLKKFF VSSGSVTINDDSSVQILAEEAVAVDQLDVQSIREGLSKANTDYSSEVAKAEAQIALECYE ALQKATE----------------------------------------------------- -----YNVHAERAGSRRYAKGMSETFQTLHGLSDKGVKVELGIPEPLWDNPSAEVVKMQR ACYKLAEDFEEHIHDWYY---------------------XXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------------------- --------------------------------------------------VEAEKQKVRA QVRRLCQENAWLRDELANTQQKLQQSEQKVATLEEEKKHLEFMNEMKKFDADDNLGFP-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----GAVRHVADIRADDMSVDGANVIGLQAGNKGASQRGMAMGSVRHVSDIKCD--SPAD QSTIGLQMGSNKGATQSGMGSG-VRHAADIKVD--ASQDMSTIGLQMGTNKGASQTGMTM GGVRHVADIRADNMDTGQGVINLQYGTNQGATQTGMDFGGRRHVA--------------- ------------------------------------------------------------ ------------HDGNKDRSQVAIQNDHLVHIYRKRWEKVSTLDEHVQRVTGIDWATNSN RIATCGADRNAYVWPTLVILRINRAATCIKWSPLENKFAVGSGARLISVCYFEEENNWWV SKHIKKPIRSTVLCVDWHPNNILIACGSSDFKARVFSGYIKDVEPKPEPTNWGKKMTLGN LMAEFSNGGGWVHSVSFSASGDKLGWVGHDSSVSIVNATLKTSNLPFVTCTFVAENTLIA AGHDCCPMAFSYGGNNISFAGRIDASKFSAMKMFRTLDARATALTTLHQNTINQLNIYSG DKAHCTKLTSSASDGTVVTWD--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------GRKVRGRVYPWGVVEVENLEHNDFIALRNMLIRTHMQDLKDVTNNV HYENFRYNRLASVGKNPLLQIEEEKKEHETKMKKMEAEMEQVFEMKVKEKMQKLRDSEAD LQKRAEQMKKQLEQQEHELIEKKKSFEKEREIWEEEER---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GEMNLEAGKELCIKVLSKTLD TNKLTAEKVEIAVLTRVDGQTVVRVLDAEEVEVVIKKHEAEEAKLEAEKKR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------LLRRQDQYRQVEDLYLKFAK RASAFNSWFENAEEDLTDPVRCNSVEEIMTLREAHNKFKESLVNAQDDFDGLAELDRQIK SYNVGPNPYTWFTIEALEETWNNLKKTIGERDDELDREQRRQEENDVLRQEFAKEANAFH AWLTDTRSAMMEGTGTLESQLEATKRKSNEVRSQRGMLKRIEDLSAEMENRIILDNRYTE HSIVSLAQQWDQLDQLGMRMQHNLEQQIQACNTSGVSEEALKEFGMMFKHFDKDKSGKLN HQEFKSCLRALGYDLPMVEEGQKDPEFEAILDGVDPNR---------------------- ------------------------------------------------------------ --------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------KIACLDFSLQKAKMKMG VQMLVEDPTQLEAMRKRESDITKERIEKILSTGANVILTTGGIDDLCLKYFVEAGAMAVR RCKKPDLKRIAKATGGQLVVTLANLEGEETFEASMLGTAEEVVQE--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---EDESARLLVSKQILNQYLVEGKDLTVQYEIFNVGESAALSVELNDGSFPEADFEKVA GNLNAQWSRIAPGSNVTHSAILRPLKPGYFNFTAAEVSYLPSEDDRQVGYTSAPGEGGII NFKDYDRKFSPHVLDWAAFAVMTLPSLGIPFLLWRSSSSKYD-------XXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX >Scolelepis_squamata XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----RQFQTSAVQRDIDQAAKYIGAGAATV GAAGSGAGIGSVFGSLVIGYARNPSLKQQLFT----XFALSEAMGLFCLMMAFLILFAFM SHYKDTGKAPETTIHRIRITLTSRNVKSLEKVCADLIRGAKDKQLKVKGPVRMPTKILRI TTRKTPCGEGSKTWDRYQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADMDQLM QYVEPAKQFSKDSIRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPI---- -MASQISKKRKFVADGVFKAELNEFFTRELAEDGYSGVEVRVTPTRTEIIILATRTQKVL GEKGRRIRELTAVVQKRFNFPEGTVELYAEK----------------------------- ---------SGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPVNEYIDSAVRHVLLRQ GVLGIKVKIMLPWDPTGKIGPKRPLPDHVSIVEPKEEPRIEAPYSEQKGGKLSKRGRGGA SGGKFRITLALPVGAVMNCADNTGAKNLYIIAVHGIKGRLNRLPTAGSGDIVMATVKKGK PELRKKVMPAVVIRQRKSIRRQNGQFLFFEDNAGVIVNNKGEMKGSAITGPVAKECADLW PRIASNASSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGKPRGLRTARKQRDHRRDQRWHDKD YKKSHLGTRWKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP RDGCLNYIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVASVSLLALYKEKKERPRSEGT ATIRTRKFLTNRLLCRKQMVVDVLHPGRATVSKTEIREKLARMYKTTPDVIFVFGFRTNF GGGKTTGFGLVYDSLDFAKKFEPKYRLARHGARKQRKERKNRQKKVRGVKKAKIGAMPRV PTVRSKTYTTPRRPFEKERLDHELRLIGQFGLRNKREVWRVRYTLAKIRKAARELLTKEE KDPKRLFEGNALLRRLVRIGVLDEDKMKLDYVLALRMEDFLERRLQTQVFKTGLAKSIHH ARVLIRQRHIRVRKQVVNVPSYVVRLDSQKYIDLAHDSALAGGRPGRVKRKNAKKGQ-GG ADXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMPLAKDLLHPSLEDEKRKCKLKRVVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCATVLCQPTGGKARLTEGCSFRRKQHMVRMSVLADALKSICNAEKRGKRQVLIRPCSKV IVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDIPIRDLERWTTQL LPSRQFGYIVLTTSGGIMDHEEARRKHLGGKILGFFFMGRMHAPGKGISQSALPYRRSVP TWLKISSEDVKEQIYKLAKKGLSPSQIGVILRDSHGVAQVRFVTGNQILRILKAKGLAPA IPEDLFCLIKKAVAIRKHMERNRKDKDSKFRLILVESRIHRLARYYKRKRVIAPNFKYES STASALVAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXMTEQMTLRGTLHGHAGWVTQIATTPQYPDVLLSASRDK SLIMWRLTRETSYGYPQKRLVGHGHFVSDVVMSSDGQFALSGSWDGTLRLWDLSTGQTTR RFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIDDGHSEWASCVRFSPNT QNPIIVSCGWDKLVKVWNLTNCKLKTNHFGHTGYLKCVTMSPDGSLCASGGKDGQAMLWD LNEGKHLYTLEGGDIINALIFSPNRYWLCAATGPSIKIWDLEGKVVVDELKPEVIGHSAD PSECLSLAWSADGQTLFAGYTDNHIRVWQVSMPARMREYKLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKVVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKLARQWNCAFLETSAKSK INVNEIFYDLVRQINRKNPDT--DKEK-ASEHINLKVTGQDGSVVHFKIKKQTALRKLMM AYCERTGIKMESTRFRFDGQPINETDTPLSLEMEEG---DVFQQQTGG--ALPMNPKPFL NSLTGKPVMCKLKWGMEYKGYLVSVDGYMNLQLANTEEYIDGTLSGNLGEVLIRCNNVLY IRGVEEEDEEGEMKDMSDAEGDDMPQAPAVGGAMDVNTALQEVLKAALINDGLARGLHEC AKALDKRAAHLCVLANNCDEPMYVKLVEALCAEHGINLIKVDDNKKLGEWAGLCKIDKDG KARKVVGCSCVVVKSYGKEGQAHDVLHDYFKSRK-------------------------- ----------------------DGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSI DSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDENTKRELMKMKQEPVRPEEGRA MADKIGADAYLECSAKTKEGVREVFENATRAALQVKKKKKGVMDDFQSSEETAFVVDEVS NIIKESIEGAIGGNAYQHNKVNQWTSNVVEQCLNQLTKLGKPFKYIVTCVIMQKNGAGLH TASSCFWDNTTDGSCTVRWENKTMYCIVSVFGLAIMFSGSAKIIKPQGEKPDEFESSISQ ALLELEMNSDLKAQLRELHITGAKEIDVQGKKAIIIFVPVPQLRPYQKIQTRLVRELEKK FSGKHVVFIAQRRILPKPTRKTKRKNKQKRPRSRTLMAVHDSILDDLCYPAEIVGKRIRV KLDGSRLIKVHLDKNQQTNIEHKTDTFSAVYKKLTGKEVNFEFPEYVLDRGGFRGGFGGR GRGRGRGRGRGKEGDKEWVPVTKLGRLVKDMKIKKLEEIYLFSLPIKECEIIDFFLGTAL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDYNGHVGLGVKCSKEVATAIRGAITLAKLSV VPVRRGYWGNRIGKPHTVPCKVTGKCGSVLVRLIPAPRGTGIVSAPVPKKLLHMAGIDDC YTSASGQTATLGNFAKATYAAIAKTYGYLTPDLWKETVFSKSPYQEFTDYLMKMSGGLDV LGLKDDDVKNFLACGTHLGSTNLDFQMEQYVYKRKPDGVYIINLRRTWEKLLLAARAIAA IENPADVCVISARSFGQRAILKFASYTGATPVAGRFTPGTFTNQIQAAFREPRLLVVTDP RTDHQPVTEASYVNIPVIALCNSDSPLRYVDIGIPCNNKSAHSVGLMWYLLAREVLRLRG TISREVPWDVMVDLFFYRDPEEAEKEPEVTDWATDTVVAPVPIGADDWSATATGDWATPT VGNEWGGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--KGKKKSVTNEVVTREYTVNIHKRIHGV GFKKRAPCAIKAIRKFAVKMMGTPDVRVDTRLNKHMWSQGIRNVPYRVRVRLARKRNEDE DSPHKLYTLVTYVPVTTFKGTQTINVESTTAKEFLVHGKYRLVRKIGSGSFGDIYLGINI QSGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRHYGEKDYNVLVMDLLGPSLE DLFNFCGRRFTMKTVLMLADQMIGRIEYVHNKNFIHRDIKPDNFLMGIGRHCNKVFLIDF GLAKKYRDNRTRAHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRGC LPWQGLKAATKKQKYEKISEKKMSTPVEILCKGFASEFAMYLNYCRGLRFEEAPDYMYLR QLFRILFRTLNHQYDYVFDWTILKQKAATTMNPEKLKQRIGGKGSARRKKKVVHRTATAD DKKLQTSLKKLNVNTIPGIEEVNMIKEDGLVLHFNNPKVQASLAANTFAVSGHAENKQIS EMLPGILNQLGPESLGNLKKLATTVPEIDEDDDEVPDLVENFDEASKGEXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKKTGPKPELTEE QKQEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGKGTIDFND FLTMMTQKMSEKDSKEEILKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQEADRD GDGEINESEFLRIMKKTSLYMGISRDSWHKRRKTGGHMPQMRKKRKFELGRPPANTKIGE QRIHSVRTRGGNKKYRALRLDHGNFSWGSEAVTRKTRIIDVMYNASNNELVRTKTLVKSC IVQIDATPFRSWYESHYTVPLGRKK-AKLTKEEEEVFTKRSKKTQKKYDERKKTAKVEQA IEDQFGTSKLIACVSSRPGRCGRCDGYILEGKELEFYMKKIKAKKGKXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXDSDTDTGSEEEVPELE-VAHAAGLPDEVVSKAKQSRSEKKA RKALSKLGLKQVQGVTRVTIRKSKNILFVINRPDVYKSPASDTYIVFGEAKIEDLSTQAS MAAAEKFKAEEEVEETGIESKDIDLVMSQANVSRGKAIKALKNNDNDIVNAIMMGRVRTK TVKKAARVIIEKYYTRLTLDFHTNKRVCEEIAIIPSKKLRNKIAGFVTHLMKRIRAGPVR GISIKLQEEERERRDNYVPEVSAIEEVDPDTKEMLKMLEMNNIPGLQVTQPIANTMKWQY KEEHPFEKRRAEGEKIRKKYPDRVPVIVEKAPKARVGDLDKKKYLVPGDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGSLYQEHHEEDFFLYIAYSDESVYGMRDLRILKL CLNICVGESGDRLTRAAKVLEQLTGQQPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAE EILERGLKVREYELRKNNFSNTGNFGFGIQEHIDLGIKYDPGIGIYGMDFYIVLGRPGYS ISKKK---------------------------------MGIKFLEFVKPFCAVLPEVQKP ERKIQFKEKVLWTAITLFLFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGIS PIVTSGLIMQLLAGAKVIEVGDTPKDRALFNGAQKLFGMIITIGQAIVYVMTGMYGEPSE LGTGICLLIILQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVN TGRGTEFEGAIIALFHLLATRQDKVRGLREAFYRQNLPNLMNLLATIAVFGIVIYFQGFR VDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAAKFSGNFFINLLG VWADVGGGGPARSYPVGGLCYYLSPPETLSHVVEDPIHATLYIVFMLGSCAFFSKTWIDV SGSSAKDVAKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIG SGTGILLAVTIIYQYFEIFVKEQSEMGGMSTLLFQVERAFQKQPTVFLNKKENFLPRYYK NIGLGFKTPREAIDGTYIDKKCPFTGDVSIRGRILSGVVMKCKMQRTVVIRRDYLHYVRK YNRFEKRHKNIS------------------------------------------------ MVNVPKARRTFCKGTKCRKHTLHKVTQYKKGRDSIYAQGKRRYDRKQSGYGGQTKPIFRK KAKTTKKIVLKMECTDCKYKKQLSIKRCKHFELGGDKKKKGQMIMF-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --PKVRGVAMNPVEHPHGGG---------------------------------------- -XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRRPARCYRYCKNKPYPKSRFCRGVPDS KIRIFDLGRKKARVDEFPLCVHLVSDEKEQLSSEALEAARICANKCLVKTAGKDAFHLRV RPHPFHIVRINKMLSCAGADRLQTGMRGAFGKPQGTVARVKIGQSILSVRSRFNHKANVI EALRRAKFKFPGRQKIYVSRKWGFTKWDLDVYEGMRANGTLVPDGVTVQYKPNKGPLAAW KHAQKVLKILGRTGSQGQCTQVRVEFLDDSNRSIIRNVKGPVREGDILTLLESEREARRL RXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMLEDRTAAKELDQWVEQLMECKQLTENQVK TLCDKAKEILAKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGRSPDTNYLFMGDYVDR GYYSVETVTLLVTLKVRFKDRITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHSNGLTLVSRAHQLVMEGYNWSHDKNVVTIFSAPNYCYRC GNQAAIMELDDALKYSFLQFDPAPRRGEPHVTRRTPDYFLMGAYKYMQELFRKKQSDVMR FLLRVRTWQFRQLSSVHRAPRPTRPDRARRLGYRAKQGVCIYRVRVRRGGRKRPVPKGAT YGKPTNQGVNQLKFQRSLQATAEERAGRRCRALRVLNSYWIGEDSTYKYYEIIMVDPSHK TIRRDPSLNWMCEANKKHREIRGLTSASRKSRGLGKGHTYAKTVGGSRRANWRKHNRMSA RRKRGIATGRLAEERKAWRKDHPFGFVARPVKNPDGTLNLMNWECVIPGKKLTPWENGYY RLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSLLDEEKDWRPAVTIKQILLGIQE LLNEPNIKDPAQAEAYTIYCQNRAEYEKRVRDQANKY------RSSKMAQHINYRMRCAL QDGRTFVGTFKAFDKHMNLILGDTDEFRRCRPKKGEKKEEKRTLGLVLLRGENLVSMTVE GPPPADEGVARVPLPGSAGGPGMGRAAGRGMGGGGGLRGPVSGVGGPSQSHMQPG--MSR GG--EGVPRFKLVLVGDGGVGKTTFVKRHLTGEFEKKYIATLGVEVRPLLFHTNRGKLAF NVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTARITYKNVPNWHRDLVRVCENIPIVLCG NKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLAKKLTGDPNLELVAMPA LQPVEVRMDPEMIEKYNKELEAAQNTALPDDDDEF------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------KGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ KFIGEGARMVRELFVMAREHSPSIIFMDEVDSIGSTRLESGSGGDSEVQRTMLELLNQLD GFEPHQNIKVIMATNRIDILDSALLRPGRIDRKIEFPAPNEEARLDILKIHSRKMNLTRG INLRKIAEMMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFELAVAKIMQKDSEKNMSI KKLWKLGFAENFALSGAAAVISKTAAAPIERVKLLVQNQDEMIKQGRLDKPYSGVIDCTT RTLKTEGVLPFWRGNLANCIRYFPTQALNFAFKDKIKALFGQKKTDGYGTKFAKNIASGG AAGAMSLCFVYSLDYARTRLANDAKV--KRMYNGLVDVYRKTLKSDGFVGLYRGFVISCV GIIVYRGCYFGFYDTLKPIVLGENANLFLSFCLGYVVTISAGLVSYPIDTIRRRMMMTSG QAVKYKGSVDCFVQITKSEGFMSLMKGAGANILRGVAGAGVLAGFDKFKEVYISWRL--- MDEIDKWVEIAKECNYLPESDLKKLCDYVSELLLEESNVQPVNSPVTVCGDIHGQFYDLK ELFKTGGQVPDTNYVFMGDFVDRGYYSLETFTLLLCLKARWPDKMTLLRGNHESRQITQV YGFYDECQIKYGNANAWRYCCKVFDLLTIAAIIDECILCVHGGLSPDIKTLDQIRTIERN KEIPHKGAFCDLVWSDPEEVETWAMSPRGAGWLFGTKVTNEFVHINKLKLICRAHQLVHE GYKYMFDDKLVTVWSAPNYCYRCGNIAAVLAFTDADNREPKLFRAVPDSER--------- ------------------------------------------------------------ KNACDHLSGFNVCNRYLVVLYYQPNKAHKKVDVEKKAGELEKMKQKYGLSTPE--MSIGV PIKVLHEAEGHIVTLETNTGEVYRGKLIEAEDNMNCQMANITVTYRDGRIAQLENVFIRG SKIRFLILPDMLKNAPMFKRVGAGRGKSAILRAAARGRGRGGGRGGRGGMQSEGGEYVEM YIPRKCSASNRIIQAKDHASIQMNFAEVDETTGRMTGQYKTYAICGNIRRMGESDDCIGR LAKKDGLIAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGTKDDEY DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTA GQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADNNIVIMLVGNKSDL RHLRAVPTDEAKAFAEKNNLSFIETSALDSTNVETAFQQILTEIYKIVSQKQIRDSPDDN NVQTITVAPTDTSAERKQRCC-------------------FQVEYAQEAVKKGSTAVGVR GNGIVVLGVEKKAVAKLQEDRTVRKIALLDDHVALAFAGLTADARILINRARIECQSHRL TVEDPVTLEYITRYIAQLKQKYTQSNGRRPFGLSTLIMGFDGTPRLYQTDPSGTYHEWKA NAIGRSAKTVREFLEKHYTTEVATEKETIKLALKALLEVVQSGSKNMEVAIMRKGEPLTM MESDDIEKYIQEIE-------------GGSGSGDDKKDKDKKKRYEPPIPTRVGKKKKKA RGPEAASKLPTVTPHTRCRLKLLKLERIKDYLLMEEEFIRNQERLKPQEEKHEEERSKVD DLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDQLEPGCSVLLNHKVHAVV GVLGDDTDPMVTVMKLEKAPQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIRPPK GVILYGQPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPS IVFIDEIDAVGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPA LIRPGRIDRKIEFPLPDEKTKRRIFQIHTSRMTLGDDVNLEDYIMSKDDLSGADIKAICT EAGLLALRERRMKVTNEDFKKSKENVLYRKNEGTPEGLYLKRKPYSPFQ-NNALDYTVAR VDDLVNWARKSSLWPLTFGLACCAVEMMHFAAPRYDMDRFGVVFRASPRQADCIIVAGTL TNKMAPALRKIYDQMPEPRWVISMGSCANGGGYYHYSYSVVRGCDRIIPVDIYVPGCPPT AEALLYGVLQLQKKIKRMKTVQMWYRKADFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYA NNSNYKNDTMIRKEAYVHKSVIEELKRIIEESEIMQEDDALWPPPDRVGRQELEIVIGDE HISFTTSKIGSLVDVSQSKDQEGLRTFYYLVQDLKCFVFSLIGLHFKIKPI--------- ------------MKSGKYVLGYKQTLKTLRQGKAKLVIIANNTPPLRKSEIEYYAMLAKT GVHHYNGNNIELGTSCGKYFRV--------------------MTEYKLVVVGAGGVGKSA LTIQLIQNHFVEEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGXGF LCVFAVNNTKSYEDINQYREQIKRVKDADEVPMVLVGNKVDLQSRTVDSKQGRLLADTFG IPYVETSAKTRLGVDDAFYTLVREIRKYMGDRYNIHSQLEHLQSKYIGTGHADTTKWEWL TNQHRDSYASYMGHFDMMNHFGIVENEAKARVKFNLMEKMLQPCGPPPDRPEDMKIELCN FSGYKIYPGHGKRSIKIDGRSFQFINAKCEKSHSMKRNPRKVNWTVLYRRKHKKGQIEEF SKKRSRRTTKFQRAITGASLSDIIAKRNQKPEVRKAQREQAIRAAKEKQKAKQAAKPRVG GKRMKLNVSYPATGCQKLIEIEDEKKVRAFYDKRMASECSAESLGEEWKGYIVRISGGND KQGFPMKQGVLTQGRVRLLLTKGHSCYRQRRSGERKRKSVRGCIVDAHLSVLNLVIVKKG EKDIPGLTDTTVPRRLGPKRASKIRKLFNLSKEDDVRQYIVRRPLPPKTKAPKIQRLVTP LVLQRKRHRLAIKKRRAAKKRDDAADYAKLLAMRMKEAKERKLERRRSASQSKXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSKSTGPKVTDKV FFDIEIGGEKQGKIVIGLFGKTVPKTAKNFKQLAEGSPTYKGSKFHRVIKDFMIQGGDFT RGDGTGGRSIYFADENFKLKHYGAGWLSMANAGKDTNGSQFFITTKKTEWLDGRHVVFGK VLEGMDVVRKIENTKTGQDKPEKDVVIADSGSIPVDTPFAVEKKPSEE--KKVAKKFVID CTHPVEDGIMDCSSFETFLNERIKVGGKTGQLKTKVVLTSEVDFSKRYLKYLTKKYLKKN NLRDWLRVVASSKEAYELRYFQINNEEEEDE---------EDEAKYGGCEGPDAMYVKLV SSDNHEFIVKREHALTSGTIKAMLSGPGQFAENETNEINFREIPSHVLQKVCMYFTYKVR YTNSSTEIPEFPIAPEIALELLMAANFLDC-------EVQQHWDMTSCWVIVHDNVYDVT DFIDKHPGGTEIFLEHGGTDATAAFTEAGHSVDAHKLLREYRIGKL-------------- --------------MSYMLQHLHNGWQVDQAILSEEDRVVIIRFGHDWDPTCMIMDETLY KVAEKVKNFAVVYLVDISEVPDFNKMYELYDPCTCMFFYRNKHIMIDLGTGNNNKINWAM EDEQEFIDIVETLYRGARKGRGLVVSPKDYSTKYRYKKLQRQLEFLEVQEEYIKDEQKNL KKEYLHAQEEVKRIQSVPLVIGQFLEAVDQNTGIVGSTTGSNYYVRILSTIDRELLKPSA SVALHKHSNALVDVLPPEADSSITMLQSDEKPDVQYADIGGYDIQKQEVREAVELPLTHF DLYKQIGIEPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVR DVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVI MATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFTTVTSKMNLSEDVDLEDYVARPD NISGADINAICQEAGMQAVRENRYVVLPKDFEKGYKNNIKKDEQEHEFYKXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX-RRVQTMSDDLKNVEFETSEEVDVTPTFDGMGIREDLLRGIYAYG FEKPSAIQQRAIRPIVKGRDVIAQAQSGTGKTATFSISILQCLDTQVRETQALVLSPTRE LANQIQKVVLALGDYMSVQCHACIGGTSIGEDIRKLDYGQHVVSGTPGRVFDMIRRRNLR TRSIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLLSATLPHEILEMTSKFMTDPI RILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKM REANFTVESMHGDMPQKEREAIMKKFRGGDSRVLITTDVWARGIDVQQVSLVINYDLPNN RELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI------ ------------------------------------------------------------ ----------------------------DPYMMGKIACSNVLSDLYALGVTECDNMLMLL GVSQKMNEKERDVVVPLMMRGFRDTATEGGTSVNGGQSVINPWMTIGGVATTVCQPNEFI MPDNAVVGDVLVLTKPLGTQVAVNAYQWLDQPDKWNRIKLVVSEDDVRKAYQRAMFSMAR LNRTGARLMHKYNAHGATDVTGFGLLGHASNLARVQKNDVAFVIHNLPIIAKMAAVSKAC GNMFGLLQGHSAETSGGLLIALPREQAAAYCKNIENQEGYQAWIIGIVEKGNRTARIIDK PRVIEVPAKEKELILSLISRTDAYFINIDAHAEECFFDKITSGTKMSLMFEVAEGGFLDI DVKIIGPDGKNIYSGERESNGKYTFAAHMDGVYKYCFSNKMSTMTPKIVMFSMDIGDKPK AHHNKLEDMINELSTALTGVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMT LGQIYYLKRFFEVRRVVMSATLRPYLTAVRNTLTAAMCLENFSSQVVERHNKPEVEVRSS KELLLTPVTISRNEKEKVLIEGSVNSLRISIAVKQADEIEKILCHKFMRFMMMRAENFVV LRRKPVEGYDISFLITNSHTEQMYKHKLVDFIIHFMEEIDKEINEMKLAVNSRARISAEE FLKQFSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLV TMQIWDTAGXERFQSLGVAFYRGADCCVLVFDVTMANTFKTLDSWRDEFLIQASPRDPEN FPFVVIGNKIDMENRAVTAKRAQQWCHGKGDIPYFETSAKEAINVEQAFQTVAKNALAQE TEIEMYNEFPDQIKLTNETNSDSCGCTAPFDARFPNQNQTRNCWQNYVDFHRCQKIEDYE PCEYFKRTYRSLCPNEWTSKWDDQMERGAFAGKIMPDHLGKDQRKTVDEKEDDKPIQSLD EGDIALLKTYGAGMYSRSIKATEDDMQNILKRVNELTGIKESDTGLAPPALWDLAADKQT LQSEQPLQVARCTKIINADTDDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNK YQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGI DPPKGVLLYGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMART KKACIIFFDEIDAVGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDT LDPALCRPGRLDRKVEFGLPDLEGRAHIFKIHARSMSVEKDIRYELLARLCPNSTGADVR SVCTEAGMFAIRARRKMATEKDFLDAVNKVIKAYAKFSATPRYMTYNXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXELEQLRQEAEQLKNQIREARKAAADTTLAQAASGVEPVGRIQMRT RRTLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAP SGSYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIVTSSGDMTCA LWDIETGQQTTSFTGHTGDVMSLSLSPDMRTFVSGACDASAKLWDIRDGMCKQTFSGHES DINAITFFPNGSAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLG GYDDFNCNVWDTLKQDRAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKIWNMSYAYLF KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES FRSITRSYYRGAAGALLVYDITRRDTFNHLTSWLEDARQHASSNMVIMLIGNKSDLEARR DVKKEEGEAFAREHGLIFMETSAKTAANVEEAFINTAKEIYQKIQDGVFDINNESNGIKL GPQHTQGGARAGGDSQSSGGMTRGTTELGELTPHNIKQLKRLNRVVFPVTYNDKFYIDVL EVGELAKLAYFNDIVVGGVCCREDKTNGQRRLYIMTLGCLAPYRRLGIGSVMLEHVLKIC EKDGNYDNVYLHVQVNNEGAIAFYDKFGFEIVEKKENYYKRIEPADAYVLQKTFR-MPKQ IKEIKDFLLTARRKDAKSVKIK-------------------------------------- ---MSKLNRDTVVEAIETVVKKKRKFTESVELQIALKNYDPQKDKRFTGTVKLRSIPKPK MKVCILGDQQHCDEAAANNLECMDVEALKKLNRNKKLVKKLAKKYDAFLASDTLIKQIPR ILGPGLNKAGKFPTMLMHSESMVTKVDEVKATIKFQMKKVLCLAVCVGHVNMSRDELQGN IVLAVNFLVSLLKKNWQNVRSLYIKSTMGPSQRIYMAESDKLNIDSIIARLLEVRGSRPG KNVQLTETEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLQAGRPVTPPRGQAKNK GKMMFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEINGTNVSTT FITCPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVMDDKNVRRRFRASNYQSTTRVKPF ICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDEL PAEFKLYLPIQ--MNDSSIQNLNDPFADESDIHIRIQQRNGRKTLTTVQGLSSDYDLKKI SKTCKKEFCCNGTVIEHPEYGEVIQMQGDQRKNMEAFLVKVGIQDNLKVHGFSALFNFQS LLTVILLLICTCAYIRSISAKMLDRNKEGLLGIFWKCARIGERKSPYVAVCCIAMAFSIL FLT--------------------------------------------------------- ------------------------------------------------------------ -----------------RVVDALGQAIDGKGSVD-GARARVGVKAPGIIPRISVKEPMQT GIKAVDSLVPIGRGQRELIIGDRQTGKTAVAIDTIINQKRFNDGQNEKAKLYCIYVAIGQ KRSTVAQIVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCAMGEYFRDNGKHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDTFGGGSLTALPVIE TQAGDVSAYIPTNVISITDGQIFLETELFFKGIRPAINVGLSVSRVGSAAQIKAMKQVAG SMKLELAQYREVAAFAQFGSDLDAATQQLLNRGVRLTELLKQGQYVPMAVEDQVCVIYAG VRGMLDKIEPSKITTFEAEFLAHIQASHQDVLKSIRENSQILPEVDAKLKEIVINFLAGF LEALYGITFAVLEIPNLKIKRPTWLKQPSAMFIFSMVLLSYFLVTGGIIYDVIVEPPSIG STTDERGNSKPVAFMPYRVNGQYIMEGLASSFMFMIGGLGFIILDQTNTPLMPKLNRILL LCVGFVCVLVSFFVCRIFMRMKLPMPKVRRSKKPPPDGWELIEPTLDELDGKMREAETDP HEGKRKVEALWPIFRIHHQKSRYIFDLFYKRRAISRELYDYCLKENIADGNLI------- ------------------------------------------------EYAQVTKMLGNG RLEAMCFDSVKRLCHIRGKLRKKVWINQSDIILVGLRDYQDEKADVILKYTSDEARSLKS YGELPEGTKINENDEDHITFDEIDDILVRFLMKLSHETVTIELKNGTQVHGTVTGVDVSM NTHLKSVKMTVKNREPVQLETLSIRGNNIRYFILPDSLPLDTLLIDDTPKSRGQKSLMNK PRSEMTPEEMDAREQEEFNTGPLSVLTQSVKNNTQVLINCRNNKKLLGRVKAFDRHCNMV LENVKEMWTEVPKTGKGKKKSKPVNKDRYISKMFLRGDSVILVLRNPLPIIIDGRGHLLG RLASLVAKTILQGQRVVIVRCEGINISGSFYRNKLKYMDFLRKRMNTNPSHGPFHFRAPS KIFWRTVRGMLPHKLHRGKEAMDRLKVFEGIPAPYDKQQRKVVPSALKVLRLKSRRRFCV LGRLSHEVGWKYQNVIQTLEGRRKVKSKAFYEKKKTQAKLRAEAVKVAKYQQVIESYGYX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIFVERTLAIIKPDSISE EIQDIILRSGFTILQKRRVHLTPEQASDFYAEHYGKLFFPSLVAYMSSGPVQALVLSRDK AISYWRELIGPTNTLKARQTHPDCLRAIYGIDDQRNGLHGSDSFSSAEREIRFFFSDSIV EPIAIGQAARDYLAKSVNPTLLKGLTQLSKQKPQDPVIWLADWLLQNNPNKPKVRMFEAR LAQGSMLKKVIESIKDLLNEGVWDCNSQGMSLQAMDTSHVSLVSLMLRCDGFDPYRCDRT LSMGINLSHMSKILRCAGNDDAITIKSADNSDTVTFMFESPNGEKVSDYELKLMDVDAEH LGIPDTDYSCVVKMPAAEFQRICRDLSQIGESVVICCTKEGVKFSASGDMGTGNVKLAQT ANVDKEEEAVVIEMQEAVTLTFALRYLNFFTKATPLSGQVSLSMSPEVPLVVEYKIADVG YIRYYLAPKIEDEQDAKSVAAYQTSSELPRGKIVAVIGAVVDVQFDEGLPPMLNALEVQG RESRLVLEVAQHLGESTVRTIAMDGTEGLVRGQVCVDTGTPISIPVGPETLGRIINVIGE PIDERGPVNAKTYWGIHQDAPEFVEMSVEQEILETGIKVVDLLAPYAKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVINLKDDSSKVSLVYG QMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTTKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIA ELGIYPAVDPLDSNSRILDKNVVGEEHYTVARGVQKILQDNKSLQDIIAILGMDELSEED KLTVSRARKIQRFLSQPFQVAEVFTGSAGKLVPLKDSIKGFSMILKGEMDHLPEMAFYMV GPIEEVVTKAETLAKD-MLMPKKNRVAIYENLFKEGVMVAKKDTHAAKHPEVEVPNLHVI NALQSLKSRGYVTEQFAWRHFYWYLTNEGIQYLRDFLHLPPEIVPSTLKRQMGGQDRQEY RKGGAGDKKADAGAGS-MGKQNSKLKPEVLDDLRANTEFTEEEIQEWYRGFLKDCPSGHL SVDEFKKIYGNFFPYGDASKFAEHVFRTFDTNGDGTIDFREFICALSVTSRGKLDQKLRW AFSMYDLDGNGYISRQEMLEIVTAIYKMVGTVMKMPEDESTPEKRTDKIFRQMDKNLDGK LSIEEFIEGAKSDPSIVRLLQCDP------------------------------------ ----------------------DDDLDDNPNQSDLIEQAAEMLYGLIHARYIMTNRGIAQ MIEKWQQGDFGFCPRVYCENQPTLPIGLSDVPGEAMVKLYCPKCMDVYNPKSSRHHHTDG AYFGTGFPHMLFMVHPEYRPKRPANSFTPRIYGFKIHPL--------------------- MTNTKGYRRGTRYMFSRKFRTRGVIPLSTYLKVYKRGDIVDIKGNGAVQKGMPFKAYHGR TGRVYNVTQHAVGVIVNKRVKGRIIPKRINVRVEHVKHS--------------------- ---------------------------------------RQNYKQVSPADPSLEWKDITD NAANTAFMLELMKGLSITASMIFKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAICPAQAITIEAETRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEY STETHEELLYNKEKLLENGDKWEAEIQANLQADYLYR----------------------- -----------------------ILKVEQKYNKLRQPYFQKRSDLIGKIPNFWVTAFVNH PQVSALLNEEDEEA----XXXEVQEFEDIKSGYKINFHFDDNPYFENNSISKEFHLNSSK STPITWKAGKDLTNKSKKRSHEEQESFFSWFLDHGDAGADELGEVIKDDIWPNPLQYYLA SEIEEDAGELEGEEDEEKQLTKEEELLLQDFSRNVSTKSSALFYGNAFIVSAIPIWLFWR IHQMDPFILFAVVTIVSTYLIALAYKNVKFVLKHKIALKRSEAVSREVMRKVSDDKKMTR QEKEERILWKKNEVADYEATTFSIFYNNSLFLLFVIVASFYLLKSFSPTLNYVLSIGSAG GLLALFSTSTK--QGKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQT VCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFSRAKSWVKELQRQ ASPNIVIALAGNKADLRMVEYEEAQAYAEENGLLFMETSAKTAMNVNDIFLAIAKKLPKT EQNIDITRQQMAEYLASIFGTEKDKVNCSFYFKIGACRHGERCSRLHNKPTFSQTVGITN LYLNPQNSAQITLSDLQVQEHYDEFFEEVFTELQDKYGEIEEMNVCDNLGDHLVGNVYVK FRKEDDADKAMKDLNNRWFNQRPV------------------------------------ ---------------------------------------------MFLTRSEYDRGVNTF SPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVVLAVEKRVTSPLIEPSSIEKIMEVDTHIG CAMSGLVADSRTMIDRARVEAQNHWFTYNERMTIESVTQAVSNLALAFGDDDAEGGAMSR PFGVALLFAGIDEKGPQLFHLDPSGTFLQYEAKAIGSGSEGAQQALQETYHKSMTLKEAC VEALKILKQVMEEKLNSTNVELATVTPGKMFKMFTKEELEKMIEQIAQKTWEMSNNVE-- -TVDEIYRYNKQQQQDILTAKRWEKDPHYFKHIKISALALL----XXRSGGNLEVMGLLL GKVDGNMMVVMDCFALPVEGTETRVNAQAQAYEYMAAYTESAKQVARLENAIGWYHSHPG YGCWLSGIDVSTQMLNQQFQEPFVAIVIDPVRTISAGKVNLGAFRTYPKGYKPPDEGPSE YQSIPLSKIEDFGVHCNQYYALDVSYFKSALDSKLLENLWNKYWVNTLSSSSLITNADYT TGQIFDLADKLEQSEAQLGRGSLMDKKSEDKLSKATKDGCKTTIEAIHGLLSQVIKDKLF NQVCGLPRRIMKETMRLKEEPVPGIQAFPDDQNARYFHVIVAGPKDSPYEGGTFKLELFL PEEYPMSAPKVRFMTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPD DPLANDVAEKWKSNESQAIEIAKQWTRTHADVDQELLDYEEEEQEEVKDVKGTYVSIHSS GFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVICQAKSGMGKTAVFVLATLQ QLEPVDNQVSVIVLCHTRELAFQISKEYERFSKYMNSVKIAVFFGGMPIKKDEQTLKTNC PHIVVGTPGRVLALTKSLNMKHVKHFILDECDKMLETLDMRRDVQEIFRMTPHEKQVMMF SATLSKEIRPVCKKFMQD------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------PPSYSDLG KSARDLFNKGYNYGFYKIESKTKASNGVAFTVNGSSNHDSGKFNGSLETKYKWSDYGLTF TEKWNTDNTLGTEITIEDQIVKGLKLAFDTQFAPQTGKKSGKIKTAYKQEYVNLNCDVDF DFAGPTIHGAAVAGYNGWLAGYQMSFDKSKLSRSNFAVGFSAKDFNLHTSVNDGSEFYGS VYQRVNSDLETGVQLNWTAGSNATKFGLAAKYTVDKDSSFRAKVNNASQIGLSYQQKVRD GVNLTLSTLVEGKNFNQGGHKVGLGVDFEA---REKILQDFRKKLLDHKELEARLKEMRE QLKDLTKQYDKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYIVGCRRQIDKSK LKTGTRVALDMTTLTIMRYLPREVDPLVYNMSVEDPGDISYSSIGGLSEQIRELREVIEL PLLNPELFARVGITPPKGALLYGPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIGES ARLIREMFGFARDHQPCIIFMDEIDAIRRFSEGTSADREIQRTLMELLNQMDGFDALGQV KMIMATNRPDTLDPALMRPGRLDRKIEISLPNEQARLEILKIHANPIAKHGEIDWEAVVK LSDDFNGADLRNVCTEAGMFAIRGERDYVIEEDFMKAVRKVAENKKLESKLDYKPVMPEN LFGVVAKFYNEYQSSTPKKIKIIDAYLFYVMLTGAIQFFYCCLVGTFPFNSFLSGFISCV GSFVLGVCLRVQVNPSNKNDFHGLAPERAFADFIFANVILHLVVMNFIG----PSQLLPL ELVDKCVGSKMHVVMKNDIEIVGILVGFDDYVNMVLEDVTEYESTPEGRRITQLEQILLN GNNITMLIPGGDGPDVIDHYENPRNVGSMDKNDKTVGTGLVGAPACGDVMKLQIKVDKDG KITDAKFKTFGCGSAIASSSLATEWIKGKNLDDAGKIKNTEIAKELCLPPVKLHCSMLAE DAIRAALKDYKVKNQMLVLVLGDLHIPHRSNNLPAKFKKLLVPGKIQHILCTGNLCTKES FDYLKTLASDVHVVRGDFDENMNYPEQKVVTVGHFRIGLSHGHQVVPWGDTESLSMLQRQ LDVDILITGHTHKFEAFEHESKFFINPGSATGAYNALDSNVSASFVLL------------ ----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXERTFIMIKPDGVMRGLVGEIIKRFEQRGY KLVAMKYMVASKEHLENHYSDLKSLPFFPGLVKYVGSGPVVPMVWEGNVVKMGRKMLGET KPQESAPGTIRGDYCIDVGRNICHGSDAVESANKEIALWFKDEELCTFDKMGDEWVYEKV APKPVKTGNKDKSKALSAKKSVLKGKHATRKRKVRTSVHFRLPKTLKLARDPRYPRKSAP KRCRMDQYAIVKYPLTTESAMKKIEDNNTLVFIVNKLANKPQIKMAVKKLYDIDVSKVNT LNRPDGEKKAYVRLAPDYDALDVANKIGIIMPAKQRMRVANEKAALKVTNRGNVPTSLKP SEDKYPVGPWLLGLFIFVVCGSAIFQIVQMV--XXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMIRFI LIQNRAGKTRLAKWYMHFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIVYRRYAGL YFCICVDVNDNNLATLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYSVVDEMFLAGEIRE TSQTKVLKQLLMLSSLEEPTIFSKIIDKTIPAKIIYEDESCLAFHDVNPAAPVHFLVIPK KLIPALSQDQMLLGHLLLVAKDVAKEEDGYRVVINNGVNGSQSVYHLHIHVLGGRQMSWP PMGGLISYFSSLFGSKERRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVQYKN LKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSMDRDRIGISKQELVSMLEEEELKGAV LSVFANKQDIEGAMTVTEVTNALGLSAIKNRKYQIFKTSAIKGEGLDEAMEWLANALST- -ALYFHIGETERKCFIEEIPDDTMVVGNYKVEMFDKVQNQYVPTMSGLGMHVEVKDPDEK AIMSRTYAANGRFTFTSHSAGEHVICLHSNSSAWFGGGQLR------------------- ---------------------------QRYREERFRQTSESTNQRVLWWSIAQTLILLIT GFWQMRHLKSFFEAKKLVMFYHVSLEHEILLHPRYFGPNLLTVVKQKLFTEVEGTCTGKY GFVIAVTTIDNIGAGMVQPSRGFVVYPVKYKAIVFRPFKGEVLDAIVTQVNKVGLFTEIG PLSCFISRHSIPPDMEFDSNSSLPCYKTKDEDIVIQQDDEIRLKIVGTRVDA-------- ----------RLYVKAVFTGFKRGLRNQHETTSLLKIDGVDTRKETDFYLGKKCCYVYKA NRRTATPGHDKPNRIRVIWGKVIRPHGNSGAVRAQFRKNLPPQAM---------MAKKTY DLLFKLLLIGDSGVGKTCLLFRFSDDAFNTTFISTIGIDFKIKTVELGGKKIKLQIWDTA GQERFHTITTSYYRGAMGIMLVYDITNAKTFDNISKWLRNIDEHANEDVEKMILGNKCDM EDKRQVPKDKGENIAREHGIPFLETSAKSNINVEQAFMDLAQAILNKMPQNEHIELHRKR HGYRLDYHERKRKKEARKAHEDARKAKKLRGLRAKMYNKKRHAEKVQMKKTIKMHEERKT KQKSEDNVPEGAVPAYLLDREGQSRAKVLSNMIKQKRKEKAGKWEVPLPKVKAESQADVF KVVKTGKSRRKGWKRMVTKVTFVGEGFTRKPPKFERFIRPMGLRFKKAHVTHPELKATFC LPIIGVKKNPSSPLYTTLG-------IEVNISELGLVTQAGKVIWGKYAQVTNNPENDGC INAVLLV-------------------------VFRAPIRPDIVSSVHSDMRKNSRQPYAV SVKAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRR INVNQKRYAICSAIAATGIPSLVMSKGHRIEQIPEVPLVLADKVEEIKKTKEAVGVLRKL KAWPDIEKVKSSRRFRAGKGKMRNRRRIQRRGPLVIYNKDNGISRAFRNIPGITLINVNR MNLLKVAPGGHVGRFCIWTESAFKQLDGLYGTWRKSSETKKDYNLPMPKMTNNDLSRLLK SEEIQSALRAPKNDNKRAVLKKNPLKNYRVMMRLNPYARVQKRTAQAKAKREALRNQRRG IASVETSGKARPRKTIA------------------------------------------- -------------RDHLNEFIDHYANIGPSNPENLPEDGKLKSEVMVKDNRRYYLDLKEN QRGRFLRVSPRSQQRSQIAIPAQGMIEFRDALTDLLDEFGPQDYEGESELPEPRSMRVEN KMFYFDVGQNRRGVFMRISETNYRTAVTIPERSWVRFRDILTDFIDKDERKMRDAQMRTT INQKLIETGERDRLKELLRTRLIECGWRDELKAYCKEIVRQKGLEHITVDDLVAEITPKG RALVPDQVKKELLQRIRTFLAQQSSMNIRNSRPEDLMNMQHCNLLCLPENYQMKYYFYHG LSWPQLSYVAEDEKGKIVGYVLAKMEEDPEDSVPHGHITSLAVKRSHRRLGLAQKLMDQA SRAMVENFNAKYVSLHVRKSNRAALHLYEKMLRFEISEIEPKYYADGEDAYAMKRTLTEF ADKF-------------------------------------------------------- ---------------FEKNSGKYAPHNKDWIKEKIYILLRKQAAKMAEEKAESKQEEVKR --HTYPLIRQSDMNEEMRVEAMELCVTACEKFSSNNENAAKLIKETMDKKFGASWHVVVG EGFGFELT---------------------------------------------------- ------------------------THIVREVDRPGSKNNKKEVVEGVTIIETPPMVVVGV VGYIETPTGMRPFNTVWAEHLSEECRRRFYKNWYRSKKKAFSKYSKKWADESGKREIEKD LAKMKKYCTVIRVIAHTQMKLLKKRQKKAHVMEIQVNGGTIPQKVDWAREHFEKKVPIKN VFSQDEMIDIIAVTKGKGMKGVTSRWGTKKLPRKTHKGLRKVACIGAWHPARVAFSVARA GQKGYHHRTEINKKIYRIGEGIHTKDGKVVKDNAATEYDQTEKTITPMGGFPHYGEVNQD FIMLRGCCAGPKKRVLTLRKSLLVHTKRRALEHITLKFIDTSSKFGHGRFQTRKEKQSFM GPLKKD----------------------------------------------DGKPINLG LWDTAGQEDYDRLRPLSYPQTDVFLICFSLISPASFENVRAKWFPEVSHHCPNTPIILVG TK---------------------------------------------------------- -----------------------KKKKKKKKMPVELEAALKEINLDETLTKKKKKKKKQF DMSEVEEALPTEETSLPSKKKKTDSDRDYTYEELLKRVFSIMREKNPDMVAGEKKRFVMK PPQMMRVGTKKSSFSNFADICKLLHRQPKHLLAFLLAELGTSGSIDGNNQLIIKGRFQQK QIETVLRAYIKEYVTCHTCRSPDTMLQKDTRLHFLQCETCGSRCSVASIKSGFQAVTG-- AALRAK--FDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVSRPEGK DYSLHRLILGTHTSDEQNHLLIASVQLPNDNAQFDASHYDSEKGEFGGFGSVSGKIEIEI KINHEGEVNRARYMPQNPCVLATKTPSSDVLVFDYTKHPSKPDPSGECQPELRLRGHQKE GYGLSWNPNVNGTLVSASDDHTICLWDINATPKEGRVVDAQSIFTGHTSVVEDVSWHLMH ESLFGSVADDQKLMIWDTRCSVTNKPSHTVDAHTAEVNCLSFNPYSEFILATGSADKTVA LWDLRNLKLKLHSFESHKDEIFQVNWSPHNETILGSSGTDRRLHVWDLSKIGEEQSAEDA EDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEEPDTPSG ELEMPAPSRARVYSDVNSHRPREYWDYESHVVEWGNQEDYQIARKLGRGKYSEVFESINV SNDEKCVVKILKPVKKKKIKREIKILENLRGGTNIITLQAIVKDPLTRTPALVFEHVNNT DFKQLYQTLSDYDIRYYMFELLKALDYCHSMGIMHRDVKPHNVMIDHENRRLRLIDWGLA EFYHPGQEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPFFHGHDNY DQLVRIAKVLGTDELFEYVDKYNIELDIRFNDILGRHSRKRWERFIHNENNHLVSPEALD FLDKLLRYDHQERLTAREAMDHPYFYPIVKEQVPETLLKKRKQNEKKNQRMRALSFKRAE KYVKEYRVMERDSIRMRREAKKHDNFYLEPEPKLAFVVRIRGINGIHPRPRKVMQLFRLL QINNGIFLRLNKATINMLRIAEPYITWGLPNLKSVRELIYKRGFGKVDARRVPLTDNAIV EQKLGKCGIICVEDLIHELITVGPNFKRASNFLWPFKLNTPLGGWKKKNNHFVDGGDYGD REDKINALLKRM------------------------------------------------ ------------------------------------------------VCELDIIFNFEK AYFMLDELLLGGEVQETSKKNVXXRSTARGI----------------XXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXEFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTI RLQLWDTAGQERFRSLIPSYIRDSSAAIVVYDITNANSFQQTSKWIDDVRTERGSDVIIM LVGNKTDLSDKRQVSTEEGEKKAKELNTMFIETSAKAGYNVKQLFRRVAAALPGMEQTE- -----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-VDAA TKKTLGKIPLLKTKAGPRDGELWVQRLKEEFQGLISYVQTNKDQDNDWFRLESNKEGTRW FGKCWYIHELLKYEFDVEFDIPVTYPATAPEIAIPELDGKTAKMYRGGKICLTDHFKPLW ARNVPKFGIAHAMALGLGPWLAVEIPDLIEKEIIHHK----------------------- ------------------------------------------------------------ -----------------LKVHEKEDGEVKFLTKGDNNSVDDRGLYAPGQMWLQKKDVVGR ARGFVPYVGIVTILMNDYPKFKYFILAMLGIFVLIHRE---MNPEYDYLFKLLLIGDSGV GKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYR GAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEY ADQLGIPFLETSAKNATNVEQAFMTMAAEIKNRMGPVSTAPNVKINASTPVKQGGGGCCE DSLGEDVLRMSNDEIVSRTRLLDNEIKIMRSEVLRISHELQAQKDKIKENTEKIKVNKTL PYLVSNVIELLDVDPQDQAEEDGANVDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDPEDL KPADLVGVNKDSYLILEKLPQEYDSRVKAMEVDERPTEQYSDVGGLDKQIQELIEAVVLP MTHRERFESLGIQPPKGVLLYGPPGTGKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGA KLVRDAFALAKEKAPAIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNQD IKVIAATNRVDILDPALLRSGRLDRKIEFPVPTEEARARIMQIHSRKMNVSSDVNFEELA RCTDDFNGAMCKAVCVEAGMIALRREATELSHEDYMDAILEVQSKKKANLNYYAKDAADQ NFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRQDKRVKLQIWD TAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDNAQVVLVGNKC DLEDERVVSTERGKQLADQLGLEFFETSAKENINVKAVFERLVDIICDKMSESLDTDPTQ TTRLTEKPNPQNAGCQCVRTHHAAVSRDYISQPRITYKTVSGVNGPLVILDDVKFPKFAE IVTLTLQDGSRRSGQVLEVSGSKAVVQVFEGTSGIDAKHTTCEFTGDIMRIPVSEDMLGR VFNGSGKPVDKGPNVLAEDFLDIQGQPINPWSRIYPEEMIQTGISAIDGMNSIARGQKIP IFSANGLPHNEIAAQICRQGGLVKLPGKSVMDDHEDNFAIVFAAMGVNMETARFFKQDFE ENGSMESVCLFLNLANDPTIERIITPRIALTTAEYLAYQCEKHVLVILTDMSSYAEALRE VSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLT GYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTREDHSDVSNQLYACYAIG KDVQAMKAVVGEEALTADDLLYLEFLQKFEKNFIAQGPYENRTIFETLDIGWQLLRIFPK EMLKRIPQDKLAKFYPRDS---------------------EKYENKTLMYACRNCDYQQV SDNPCIYVNKIQHEVDELTNIIGDVIVDPTLPRTEHHPCPQCGHKEAVFFQSQSRRADEG MRLYYVCTNGTCQHRWTE-PEYKVADISLADWGRKAIDIAENEMPGLMSLRKKYGKEKPL KGARIAGCLHMTLQTAVLIETLQELGAEVRWSSCNIFSTQDHAAAAMAKAGVPVFAWKGE TDEEYMWCVEQTIMFGD-KPLNMILDDGGDLTNLVHEKYPQYLPEIKGLSEETTTGVHNL YKMMQKGALKCPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGKVACVAGYGDV GKGCAQALRAFGARVILTEIDPINALQAAMEGYEVSTIEEVVKEARIFVTTTGCKNIITG PIFEQMLEDTIVCNIGHFDCELDIKWLNENCASKDNIKPQVDRYTMKNGRHIILLAEGRL VNLGCAMGHPSFVMSNSFCNQVLAQIELWTNTAKYPIGVHFLPKKLDEEVALAHLEHLGA KLTVLSDDQASYLGIPKEGPFKPDHYRY--------ANTVEEPLDLIRLSLDERIFVKMR NDRELRGRLHGYDQHLNMILGEVEETITTVEIDEETYEELYKQKKRQVPMLFVRGDGVIL VSPPMRT----------------------------------------------------- -------------------------FFLTKMFHPNVASNGEICVNTLKKDWKSDYGVKHI LLTIKCLLIVPNPESALNEEAGKMLLERYEDYCSRAKLFAELYARPMFKSLLESATSNPF ASPFGLKVNEQRLIAAADDEYSCEFGDQKYYALCGLGGILSCGITHTAVVPLDLVKCRIQ VDSAKYGNIVQGFRVTFAEEGMRAFGKGWAPTLIGYSMQGLCKFGFYEVFKNVYGNMIGE ENTFLWRTSLYLAASASAEFFADIALCPMEAVKVRIQTQPGWAMTLREGVPKLMQEEGIG GFYKG-VPLWGRQIPYTMMKFACFERTVEALYKFVVPKPRAECSKGEQLIVTFVAGYIAG VFCAIVSHPADTIVSKLNQDKTASFVGVAKSLGWGGMWKGLGPRIIMIGTLTALQWFIYD SVKVYFRLPRPPPPEMPESLKAKLEHWLKERYVAVALLPIIPAALAFIMDTLLSAMVLHS YWRLSGVAEDYIHLTILAFGSLCYFNYFDVGFGNAVQTLYSQLNEQQDEDASELIFPKEF ENAETLLISEVQRKQQNESAEDEQELSEVFMKTLNATQRFSKFKNRETIAA--------- ---------------------------------------------------TSQPHLSKQ DLENLDISKLTPLTPEVISRQATINIGTIGHVAHGKSTLVKALSGVQTVRFKNELERNIT IKLGYANAKIYKCDKPNHPRPQCYTSRGSAHADEFPCDGQGCGKFKLIRHVSFVDCPGHD ILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILIIQNKVDLVKESQ AMEQHEQIQRFVQGTIAEGAPIIPISAQLKYNMDAVCEYITKKIPIPPRDFTSQARLIVI RSFDVNKPGCEVDDLKGGVAGGSILKGVLRVGQEIEVRPGIVSRDKDGKLTCKPIYSRIV SLFAEQNDLQYAVPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPDIFVELEISYFLLR RLLGVRTEGDKKGAKVQKLSKNEILMVNIGSLSSGGRVQAVKADLAKIMLTHPVCTEIGE KIALSRKVEKHWRLIGWGQIRRGVTVKP-------------------------------- ------------------------------------------------------------ ------------------------------------------TLRFKPMLQRGIELNSLD ASWVSSASWYFLNVFGLRSMYNLILGQDNAADQTRMMQEQMTGAAMGMPQDPSKAFKAEW EALQISEHKWALEDVEEELLMFLWDWFTGMLNYLGLYKKSGKLVFLGLDNAGKTTLLHML KDDRMAQHVPTLHPTSEELAMGGMRFTTFDLGGHTQARRVWKDYFPAVDGIVFLVDAFDR ERFVEAKAELDSLLLDEQVANAPVLILGNKIDKPGAASEDEIRAMFGLHGQTTGRTTVPK SELRPMELFMCSVLKRQGYGEGFRWMAQYIN----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ SVDAAAHRVFSHAYFHHRQLFDEYENETALCKRFTLFVTKYDLMAKNNLIVPILEEQMPS IKLQSSDGETFEVDVEIAKQSVTIKTMLEDDEDEEEAVPLPNVNCAILKKVIQWCTYHKD DPPPPEDDENKEKRTDDISSWDVEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMI KGKTPEEIRKTFNIKSDFTPAEEEQVRKENEWCEEKXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSASAVYI LDVKGKVLICRNYRGDIDMSVIDKFMPLLMDKEEEGSLTPIIHHGDVAFIYIKYNNLYLV STTKKNANIALVFQFLHRIVQVFCEYFKELEEESIRDNFVIIYELLDELMDFGYPQTTDS KILQEYITQEGHKLDIAPRPPMAVTNAVSWRSEGIKYRKNEVFLDVIESVNLLVSANGNV LRSEIVGAIKMRVYLSGMPELRLGLNDKVLFESTGRGKSKSVEIEDVKFHQCVRLSRFEN DRTISFIPPDGEFELMSYRLNTHVKPLIWVESVIERHAHSRVEYMIKAKSQFKRRSTANN VEIVIPVPTDADSPKFKTTTGSCKYSPELNAVIWTIKSFPGGKEYLMRAHFGLPSVQNEE AEGRPPIQVKFEIPYFTVSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRTXMGVLEK IAEIEAEMNRTQRNKATMGHLGLLKARLAKLRRELIEPKGGGGGTGEGFDVAKTGDARIG FVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDG KGRGKQVIAVARTCSLIYIVLDVLKPLQHKKLIEKELEGFGIRLNKDPPNIHFRRKDKGG INLTATVNQSELDMDLVKSILGEYRIHNADIVLRYDATTEDLIDCVEGNRVYIPCIYVLN KIDQISIEELDIIYKIPHCVPISAHHKWNFDDLLEKMWEYLHLVRIYTKPKGQLPDYNAP VVLKDGATSVEDFCNKLHRSIIKEFKNAIVWGSSVKHQPQKCGKEHILCDEDVVQIIKKM AKHHPDLIFCRKQPGVAIGRLCEKCDGKCVICDSYVRPNTLVRICDECNYGSYQGRCVIC GGPGVSDAYYCKECTIMEKDRDGCPKIVNLGSAKTDLFYERK-------PRLPPISGDKL TGKNDLRKIPVPSHRYTPLKENWMKIFTPVVDHLHLQIRFNLRTRNVEIKTCKQTTDIGA LQKATDFVKAFTLGFEVDDALALVRLDDLFLESFEVTDVKPLKGDHLSRAIGRIAGKGGK TKFTIENVTKTRIVLADSKVNIMGSYQNIRIARTAISNLILGSPPSKVYGNMRAVASRSV ER---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------KNTILKRYDGRFKDIFQEIYESTYVKEFES SGIWYEHRLIDDMVAQALKSNGGFVWACKNYDGDVQSDVVAQGYGSLGLMTSVLMCPDGK TIEAEAAHGTVTRHYREHQKGNPTSTNPVASIFAWTRGFEHRAMLDNNPDLARYCQVMEK ACVDTIDSGKMTKDLAGCIYGLKNIKPDQYLNTGDFLDAIVEEFNMGKIISKIFGKKEMR ILMLGLDAAGKTTVLYKLKLGQSVTTIPTVGFNVETVTYKNVSFNVWDVGGQDKIRPLWR HYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMKPHEI QEKLGLTRIRDRNWYVQPSCATSGDGLYEGLTWLTSNAKSXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXX-VQEVREVTRIERIGAHSHIRGLGLDDALEARNVSQGMVGQTSARRAAGVILEMI KEGRIAGRAILIAGHPGTGKTAIAMGMAQALGIDTPFTAIAGSEIFSLEMSKTEALTQAF RKSIGVRIKEETEIIEGEVVELLIDRPATGTGAKQGKLTLKTTEMETVYELGQNMMESLT KEKVQAGDIITIDKATGKITKLGRSFTRARDYDAMGPQTKFVQCPEGELQKRKEVVHTVS LHEIDVINSRTQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIVPGVLFVDEVHM LDMECFSFLNRALESDLAPILIMATNRGITRIRGTNYQSPHGIPIDLLDRLLIISTTPYD EKEIKQILKIRCEEEDVEMSDDASTVLTRIGMETSLRYSIQLITTASLVCRKRKGTEVSV EDIKRVYSLFLDESRSTQFLKEYQQEFMFHEMAEFDLTTRMGQYLDRHLVFPLLEFLSVK EIYDDTEMLKGKLDLLSNTNMVDFAMDVYGSLYPDQEVPSMLRDKRSNVVAELKRLQAET EPITKIFEHEDVKISSARDGRQLFEFLNTNYSFKQEMVDTLYRFGKFQYECGNYSGAAEY LYFVRVLLPTTDKNYLSALWGKLASEILMQNWDTALDDLNRIKEVIDNALQSLQQRTWLI HWSLFVFFNHPKGRDYIIDMFLNQQPYLNAIQTMCPHILRYLTTAVITNKTVLKDLVKII QQESYTYKDPITEFLECLYVNFDFDGAQQKLRECETVLMNDFFLVACLDDFIENARLFIF ETFCRIHQCISINMLADKLNMSPDEAERWIVNLIRNARLDAKIDSKLGHVVMGTQAISPY QQVIEKTKGLAFRAQMMAVNIKKK-----MGVTVETIQPGDGVTFPKAGQTVIVHYTGTL TNGNKFDSSRDRGSHFRFKIGQGEVIRAWDEGVAQMSKGQRAKLTCTPDYAYGSKGVGGV IPPNATLIFDVELFGMEMPKYYCDYCDTYLTHDSPSVRKTHCSGRKHKENVQIYYQKWLE DQVQKLVDDTTAAFKAGKIQSNPFAHPKAAIPPPSNLDGGPPGPMMPMMG----GMGPPM RPPMGPMGPM-P-----EPLTLERDIHRAVELLDHLQRSGEIHKLAALQKVLQSDFCNAV REVYEHIYETVDITGPPEVRANATAKATVAAFAASEGHAHPRVVELPKTEEGLGFNVMGG KEQNSPIYISRIIPEGVADRHGGLKRGDQLLSVNGISVEGEPHEKAVDLLKAASGMVKLV VRYTPKVLEEMEARFDRQRMARRPQVSCLIAVALAEPTTYFREEFWESRWVESTKKGAEQ GKFKWTAGKFYGDAEKDKGIQTSQDARFYGLSAKFDQSFSNEGKTLVIQFTVKHEQNIDC GGGYVKVFAEDLEQKDMHGDSPYYIMFGPDICGPGTKKVHVIFNYKGKNLLTKKDIRCKD DVYTHLYTLIVRPDNTYEVKIDNSKVESGTLEADWDFLAPKMIKDPEAKKPDDWDDREKI DDPEDTKPEDWEKPEHIPDPDAKKPDDWDDEMDGEWEPPMIDNPDYKGEWKPKQIPNPDY KGPWIHPEIENPDYEADESLYKYEKIGALGFDLWQVKSGTIFDNILITDDEKLAEEVGNE TWGATKDAEKAMKDKQDEEEKKQREAEEAARKEKEGDDEDAPEE------EPSLFTVKAI LILDNDGNRIICKYYDETYTTTKEQKNLFSKTHRANAEIIML-GLTCVYRSNVDLFFYVI GSVQENELILVSVLNCLYDSVSTMLRKNVEKKALLENLDGVFLAIDEICDSGIILEADPN AVCNRVSFRSDDVPLGEQTVAQVIHQAKEQFKWSLLKMNIFRLCGDLSHLLAIILLLIKI WKTRSCAGISGKTQIMFCIVFLTRYLDLFTNFISLYNSSMKVIFIASTVATVYLMFAKFR ATYDSNHDTFRMEFLIVPVAGLSFLVNHDFSPFEILWTFSIYLESVAILPQLFMISKTGE AETITSHYLFALGSYRGLYILNWIYRYYFEGFFDLIAVVAGCVQTVLYCDFFYLYITKVW KGKKLTLPAMKIEEVKSTTKTQRIATHTHVKGLGLDDNGYAIQSAAGLVGQELAREAAGI IVEMIRSKKMAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSSEIKKTEV LMENFRRAIGLRIKETKEVYEGEVTELTPVETENPMGGYGKTVSHVIIGLKTAKGTKQLK LDPSIYESLQKEKVEVGDVIYIEANSGAVKRQGRSDTFATEYDLEAEEYVPLPKGDVHKK REVIQDVTLHDLDIANARPQGGQDIISMMGQLMKPKKTEITDKLRKEINKVVNKYIDQGI AELVPGVLFLDEVHMLDIECFTYLHRALESTIAPICIFATNRGKCTIKGTEDLISPHGIP LDLLDRLMIVRTLPYSQEEMMQIIKIRAQTENIVVNDESLQVLSEVGVKTTLRYAVQLLT PSNMLAKINGKDDISKEEIEEINELFFDAKSSAKILAEQEDKFMK--------------- -----------------------------GPQRSVEGWILFITNVHEEATEDDIIDKFRD FGEIKNLHLNLDRRTGFLKGYALVEFETFAEAQSAMEKLNGEDILGQNISVDWAFVRGPS K----------------------ELIQSSQITPALALKVLLQFDKAINTALSTRAKNRIS FKGKLNTYRFCDNVWTFVLNDVEFKSVDKVKIVACDGKN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GKDFSKVDRSAAYAARWVAKSLVKAGLCRRVLVQISYAIGVAKPLSVFVSSYGT GVRPDAELLEIVNKNFDLRPGVI------------------------------------- --------------------GIVAGPVSEENFFEWEAYILGPEGTFFEGGVFPARLTFPP DYPLGPPKMKFTCEIFHPNIYSDGRVCISILHAPGDDPMGYESSAERWSPVQSVEKILLS VVSMLAEPNDESAANVDAAKTWREDRKKFVEIAEQTVRKSLGFMRLEKCYFCSSTVYPGH GSTFVRNDCKVFHFCRSKCLRAFKKKRNPRKVKWTKAFRKAAGKELTVDP-XHFEKRRHV PVKYERKVWQDTVKAMKRIEEIKTKRQNQYVLNRLKKGKSIRKAADVKEVQKNIHLI--- ---MAKYKVVMVRHGESEWNKENKFCGWFDADLSELGVNEAKSAGQMLKEKGFDFDIAFT SVLKRAIKTLYHIQNELDLHWIPVIRHWRLNERMYGALQGLNKAETAAKHGEEQVKIWRR AYDTPPPAVEVNDPRFPGLDPKYQYVDKQLIPRSECLKDTVARALPFWYDFIVPEILKGQ RVLIAAHGNSLRAMVKYLDNMSDADIMALNIPTGIPLVYELDENLKPVKHYYLADEAAVK AAIDKVAAQGKAKMEQQDVFYSKHQYIETASGNKVSRHSVLCGSQNIVLNGKTIIMSDCI IRGDLANVRIGRHCIIADRAVIRPP----------------------------------- --------------------------------------------MSFLFGGRNNKTFKPK KNIPEGSHQYELMKHAATTLGSGDLRQAVQLPDGEDLNEWVAVNTVDFFNQINMLYGTIT EFCTEESCPVMCASPKYEYHWADGHTVKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKI GVPFPKNFQSIAKTILKRLFRVYAHIYHQHFDQVIQLAEEAHLNTSFKHFIFFVQEFSLV DKRELAPLQDLIDKLTSKDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------------------- ------------------------------------------------------------ ------------LKRTFQVIVVEYHGHQLANSLAKENIETTVITDSAVFAIMSRVNKVII GTHTVMANGGLKAIGSHALALAAKYHSVPMIVCAPMFKLSPQYLCSHDDAFNKFVSPEDI SNPVFDYVPPGLVTLYISNIGGNAPSYVYRLLSELYHMIIPIRCFTCGKVVGNKWESYLG LLQAEYTEGDALDALGLKRYCCRRMLLAHVDLIEKLLNYAPLERKSPDAVEGRKHIDVQT ELYLEELDGRVEEADVDCQTDAFLDRPPSPLFVPAKSGKDVATQIMEGDLFDFDIEVKPI LEVLVGKTIEQSLLEVMEEEELSNLRSQQRAFEELRNAELVEQQRLEEQERRHREEKERR MKQQKEILRKERETSDKIAARAFAQSYLADLVPSVFGTLADNGYFYDPVERDVEQGFMPW LMDRVEEQLTRSLIGRTVLDGMLREVVAKRLEAFAEMRARGTFKEYRVVGRSIPTQINRV PKLYAMRLFAPDQPTAKSRFWYHSSMLKKMKKGKGEIVGCTQINEKYPLKVKNYGIWLRY NSRSGTHNMYREYRDMTTASAVTQCYRDMGARHRARAGSIQIIRVEVVPSSKTRRTGIKQ FHNSSLKFPLPHRVAKRLHAPRFTTKRPHTHFTAHEQMKAFWEKNQNRPNSPWTIYRFHL PMSTSLAHRITGIAMGVVLYGIAIGTYVAPGDFPSYVEFLKNLNVATPIWFTLKTLCAFP LVYHYINGIRHLSWDAGVGLRLPTQYKTGAAILASVAYWDVSISLSAYRDQHYRGNRVEQ ERHLLESTTLYIGNLSFFTTEEQIHELFGRAGDVKRIIMGLDKFKKTPCGFCFVEYYTRE DAENSMRYVNGTRLDDRIVRSDWDAGFKEGRQYGRGKSGGQVRDEYRNDYDDGRGGYGKI LTHKIKPNYTLKFTLAGHTKAVSSVKFSPNGDWLASSSADKVIKIWGAYDGKYEKTISGH KLGISDVAWSTDSRLLVSASDDKTLKIWDVSTGKCLKTLKGHSNYVFCCNFNPQSNLIVS GSFDESVRTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG KWIVSGSEDNTVYIWNLQTKEVVQKLQGHTDVVLCCACHPTENIIASATLENDKTIKLWR SDVMIIYHDLFTDEELLSDTYKGVVYKVAGKDDSLIGGNKSSGINIVLANKKEYMKHIKE YMARVKSYSFFVGRVLCKWETPYLYYFKQGLRAEKVXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVLIAIGVLLV FLLCCFCICKKCCKKRKKKEGKKGLKGAVDLKSVQLLGSTMKEKVQPDLEELGENMEDNE DAESTKSEVKLGKLQFSLDYDFQKAELSVGVIQSADLPGMDMSGTSDPYVKVYLLPEKKK KYETKVHRKTLNPVFNETFVFKVPYAEIGSKTLVFAIYDFDRFSKHDQIGQVQVPLNSVD LGRVVEEWRDLTSPESE-EKENKLGDICFSLRYVPTAGKLTIVILEAKNLKKMDVGGLSD PYVKIALYQGSKRLKKKKTTIKKRTLNPYYNESFTFEVPFEQIQKVSLIVTVVDYDRIGT SEPIGRVVLGCNSTGTELRHWSDMLANPRRPIAQWHTLQEMPEKNMVLADLGRKITTALR SLSSATVINEQVLDSMLKDICKALLEADVNIKLVKKLRENVRAVIDFDEMAAGLNKRRMI QSAVFKELVKLIDPGVKTWTPHKAKPNVIMFVGLQGSGKTTTCTKLAYYYQRKNWKTCLV CADTFRAGAFDQVKQNATKARIPFYGFMTKGNEQESMARLKKLMTMMDS----------- ----------------------NDHELDNQE--GAKLFTRGRIQRVARGAGVSQKEVQEL LTQKFAQMVKKMGGIKGLFK-GGDMTKNVPAQMAKLNTQMAKMMDPRVLQQMGGMGGLQS MMRQFQQGAMSIMAYNGAAIIAMKGKDCVAIASDRRFGIQAQTVGMDFEKVFEMGPKLYM GLAGLATDVQTVHQKLKFRLNLYELRENRNIKPKTFMSMVSNLLYERRFGPYFIEPVIAG LDPKTSEPYICSLDLIGCPMVTEDFVVCGTCTEQLYGMAESLWEPDMEPDQLFECISQAL MNAVDRDAVSGWGGIVHIIEKDKVTTRTLKARMDMTSKDYYFDSYAHFGIHEEMLKDEVR TLTYRNSMYHNRHLFKDKVVLDVGCGTGILCMFAAKAGAKKVIGIECSSIVEYAEKIVKA NKLDHVVTLVKGKVEEVKLPDGIEKVDIIISEWMGYCLFYESMLNTVLYARDKWL----- ------------------------WWDNVYGFDMSDVRKVAISEPLVDVVDPKQVVTNSC LVKEVDIYTVKLEDLSFSAPFNLQVRRDDYIHALVAFFNIEFTKCHKKTGFSTAPEARYT HWKQTNDTITCNKGEEVFGIFHTKPNKNNVRDLDFTIDVDFQGELSTVRESNSYKMRMVK EDRQTWKTNYFMKMTQMLDEFPKCFVVGADNVGSKQFQSIRMALRVLMGKNTMMRKAIRG HLDTNPSLEKLLPHIKGNVGLVFTKLDLSEVRDKLLNNKVAAPAKAGAIAPKDVILPAQN TGLGPEKTSFFQALAIPTKITKGTIEILNDVSLIKEGDKVGASEATLLNMLKIYPFTYGL AVQQVYDSGTVFSPEILDITDDNIRMKFMQGVCNIASVSLAIGYPTVASAPHSIVNGFKN CLAIAAATEITFKQAETMKESSQRGKLIAVIGDEDTCTGFLLGGIGELDRNRRANFLVVD KGTSISDIEESFKQFTRRQDIAIILINQNIAEMIRHILDSYTEAIPAVLEIPSKD----- ------------------------------------------------------------ ---------------------------------------------------FAFKIYDMD KDGYISNGELFNVLKMMVGNNLKDAQLQQIVDKTIIFADSDGDGKISFEEFCAVVGNLDF YKKMVVEVMTYITSWDEFSKAAEQLYIQDPMKCRFVVKYIHSAGQLCIKITDDQVCLQYR TEHAQDVKKLEKLTSQLMRHMASKE----------------------------------- --------------------------------------------------AALERIKEDR PITIKDDKGNVSKCIADIVSLFITIMDKLRLDVKAMDEIQPDMIELQECMTRLSILPADF EGKQKVQKWLDTLKEMEASDELSEGQVRQLLFDLESAYSAFNRVLHNMLSSMVREHQHKQ VARKEIQEQRKREATTATKLTHALVDHLNAGVAQAYVNQKKLDTETKILQANTTTFAKQT ILWLKLVEDFNTALKEIGDVENWAKSIENDMRTISSALEYAYKKRMVTKPINGKENGENR VVRTKRFPKFYPTEDRPRKLRNPFRFHKRNLRSSITPGTVLILLAGRHKGKHVVFLKQLG SGLLLVTGPYHLNGCPMRRINQRYVIATKTRLDISKVQLPERVNDEYFKRVQNKKQKPAE GEIFDTKKEDYSVSDVRKEDQLSVDKQLLDVIRAHPEKKYMFGYLGSLFSLSNKQYPHKM IFLSWLFGKKKTPQEMLKQNQRALNKAMRDLDRERQRMEQQEKKVIADIKKMAKQGQMDA VKVMAKDLVRTRRYVKKFIMMKANIQAVSLKIQTLKSNDAMAQAMKGVTKAMATMNKQLK LPQIQKIMMEFEKQSEIMEMKEEMMNDAIDDAMGDDDDEEESEQIVNQVLDELGLQMADQ LTDLPAAGKTPAKQPVPVSDADADLEARLENLKR-SKYCDFCLGDEMENKKTGNKEELVS CADCGRSGHPTCLQFTNNMIISVRKYPWQCIECKSCGLCGTSDNDDQLLFCDDCDRGYHM YCLTPPLSEPPEGSWSCHLCIKEFYG-VERIINIYPLGNYTFGTKDALFEKDKSVQARFQ RMKEDFENHGMRRSVEGVLIVHEHGLPHVLLLQLGTTFFKLPGGELSQGEDHIEGLKRLL TEMLGRSDQAPVNWVIEDVIGNWWRPNFEPPQYPYIPAHITKPKEHKRLFLVQLPEKAQF AVPRNYKLVAAPLFELFDNASGYGPLISSLPQALSRFNLIY-FTPSGTTPTGAKAMSMMT PTPGHMVHMTLEQMQAWTWQREIDERNRPLSDDDLDVMLPKGYKVLPPPAGYIPIRTPGR KLTATPTPMGNTPTGFKMQNQVVDLQPKGNLPMMKPDDMQYFDRKIMKLLLKIKNGTPPM RKAALRQITDKAREFGAGPLFNQILPLLMSPTLEDQERHLLVKVIDRILYKLDDLVRPYV HKILVVIEPLLIDEDYYARVEGREIISNLAKAAGLATMISTMRPDIDNMDEYVRNTTARA FAVVASALGIPSLLPFLKAVCKSKKSWQARHTGIKIVQQIAILMGCAILPHLRNLVEIIE HGLVDEQQKVRTITALALAALAEAATPYGIESFDSVLKPLWKGIRMHRGKGLAAFLKAIG YLIPLMDAEYANYYTREVMLILIREFQSPDEEMKKIVLKVVKQCCATDGVEPQYIKDEIL PPFFKHFWNQRMAVERRNYRQLVDTTVEIANKVGASEIITRIVDDLKDESEQYRKMVMET IEKIMANLGAADIDSKLEEQLIDGILYAFQEQTTEDVVMLNGFGTVVNALGKRVKAYLPQ ICGTILWRLNNKSAKVRQQAADLISRIAVVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLG SILGALKSIVNVIGMTKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGAEFVS AREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVC TTVAIAIVAETCSPFTVLPGLMNEYRVPELNVQNGVLKSLSFMFEYIGEMSKDYIYAVAP LLEDALMDRDLVHRQTSMAAIQHLALGVYGFGCEDALTHLLNYVWPNVFETSPHVVQAFM GAIEGIRVGTGSSNVLQYTLQGLFHPARKVRDVYWKVYNTVYIGAQDAMVPAYPRIANDE KNQYIRYELDYMLEDFMVDDEDYDLEYSEDSNSEPDVDLENQYYNSKALKEDDPQGALDS FQKVLDLEGQDKGEWGFKALKQMIKINFKLGRFPEMMNRYKQLLMYIKSAVTRNYSEKSI NSILDYISTSKQMELLQNFYETTLEALKEAKNDRLWFKTNTKLGKLYFDREEFGRLQKIL KQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEKSLHIKSAIPHPL IMGVIRECGGKMHLREGEYENAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGIN PFDSQEAKPYKNDPEILAMTNLVSAYQNNDINEFEKILKTNRRNIMEDPFIREHIEDLLR NIRTQVLIKLIRPYTSIHIPFISKELNIDVGEVENLLVSCILDNTVNGRIDQVNQVLQLD SGGARYGAVDKWTQQLASLHQSIVNKMAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXILSFSTRLFSVLRFESVIHEFDPYFNYRTTRFLTEEGFYNF HNWFDDRAWYPLGRIIGGTIYPGLMVTSAAFYNVMHFFNVTIDIRNVCVFLAPLFSSFTT IITYILTKELKDAGAGLVAASMIAIVPGYISRSVAGSYDNEGIAIFCMLFTYAMWIKAVK TGSVFWGVICSLAYFYMVSSWGGYVFLINLIPLHVLALMLTGRFSHRIYVAYCTVYAVGT ILSMQISFVGFQPVQSSEHMAALGVFGLCQIFAFIDYVRSKLSKEQFDILFRSVTLFAAV IIGTATGKISPWTGRFYSLLDPSYAKNNIPIIASVSEHQPTTWSSFYFDLQMLVFMFPAG LYFCFKKLTDANIFIILYGVTSIYFAGVMVRLMLVLAPVMCILSGIAVSATLTTYMKNLD SSRRADSNYPIKNEIATSVIFIVTAFLIMYTFHCTWVTSEAYSSPSIVLSAKGGDGGRII FDDFREAYYWLRHNTPEDAKIMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMAS TEDKAYEIMRELDVDYVLVIFGGLTGYSSDDINKFLWMVRIGGSTDRGEHIKENDYYTPQ GEFRVDKEGSPTLLNCLMYKMCYYRFGSVYTESGKATGYDRVRNAEIGNKDFELDVLEEA YTTEHWLVRIYKVKDLENRGN--------------------------------------- ------------------------------TTKLYPTHDATTFSVLGRVVSGTLHANQEV RILGENYTLQDEEDSRHGQVGRLWISEARYKVEVNRVPAGNWVLIEGIDQPIVKTSTITE PSGNEEAHIFRPLKFNTQSVIKIAVEPVNPSELPKMLDGLRKINKSYPLVTTKVEESGEH VVLGTGE----------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------TVLARRRGHVTQDAPIPGSP LYIIKAFLPAIDSFGFETDLRTHTQGQAFCLSVFHHWQIVPGDPLDKSIIIRPLESQPAT HLAREFMIKTRRRKGLSEDVSINKFFDDPMLLELAKQDVMLSYGMQETFCLFDNRGDNKI AAHQLGDTLRAMGQNPTEAEVRKCNDPEPYRSXK-----XSTISKNRDTSQLEDFIEGFK VFDKEQNGLIQSAELRHLLTSLGEKMSDDEVNELFIGQEDPQGNVNYEE--------MPE LTFNLDNGYLEGLVRGFKAGVLKQTDYMNLVQCETLEDLKLHLQSTDYGSFLANEASPLT VSVIDDKLKEKLVIEFQHLRNNAFEPLATFLDYITYSYMIDNIVLLITGTLHQRAISELI PKCHPLGSFEQMEAIHIAATPAELYNAVLVDTPLASYFADCISEQDLDEMNIEIIRNTLY KSYLEDFYRFCEELGGATADVMCEALAFEADRRAFIITINSFGTELTKDDRSKLYPRCGK LHPDGLASLARADDYEQVRALAEYYGDYRSLFEDAGNNPGEKTLEDKFFEHEVNIMKNAF MQQFNFGVFYSYVKLKEQENRNIIWISECIAQRHRAKIDSYIPIF--------------K VLDAPELQDDFYLNLVDWSSQNVLSVGLGSCVYLWSACTSQVTRLCDLSSDSDSVTSVSW SERGNFVAVGTYKGYVQIWDVSMNKRISVLEGHSARVGALAWNADMLSSGSRDRLILQRD IRTPSVLQERRLTGHKQEVCGLKWSPDHQHLASGGNDNKLFVWNMNSLSPVQTYTDHLAA VKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCVDTGSQVCNLAW---------- ------------------------------------------------------------ ----------------------IYYILSGNGYRIDIKWFLEGIPPYLWCNIGIGLAISLS VVGAAWGIYTTGSSILGGGVKAPRIRTRNLVSIIFCEAVAIYGIIMAIVISNGKNYYAGY AMFGAGLTVGFSNLFCGICVGIVGSGAALADAQDASLFVKILIIEIFGSAIGLFGVIVSI LQTTKVSMG----ATRRLQKELRDVVDETNLLQWSGLIVPENPPYNKGAFKIKIEFPAEY PFKPPRITFLTSIYHPNIDEKGQVCLPIISAENWKPATKTDQVIQSLVALVHDPEPEHPL RADLAEEFSKDKKKFMKNAEDYTKKHSEKRPSDXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------- --------------------------------------LSDTNNDVVQVFDQGRFLHQFG WTGNEKGALKQPFGVSDDGE-NILVVDSGNRRIQVFRRDGTFVSMIELNQPRGMVVTQDG HVWVAD-------------AAGPIAERNQDATIYVGGLDDKVGEAILWELFLQAGPVVNV HMPKDRISMAHQGYGFVEFMAEEDADYSIRIMNMIKLYGKPIRVNKASAHQKNLDVGANI FIGNLDPEVDEKLLYDTFSAFGVILQTPKIMRDQDTGNSKGFAFVNFGSFESADAAIEAM NGQYLCNRAISISYAFKKEAKGERHGSGAERLLAIQNPLSQATMPHQLFADAPPPPTSPP MAPPPPPPSMAGPPPSMPGVPP-----PPMPPTSGAPPPPVPPP-------APPPGM--- PPMPPPGGMP----------KVEVKK-TNPLFEKRPKNFGIGQDIQPKRDLSRFVKWPKY IRLQRQRAILMQRLKVPPSINQFTDTLDRQTATQMFRLLDKYRPETKQDKKQRLKSRAEE RVKGKPDAPSKRPAVVRSGVNTVTSLIEQKKAQLVIIAHDVDPLEIVLFMPALCRKMGVP YCIVLGRVVRRKTATCLALDRTNPEDRSSLNKLVEAVKTNFNERGEEIRRHWGGGIMGNK SQARVAKLEKAKAKELVQRMRYVAAYLLAVLGGKSSPTDADIKKILSSVGIDAESENIKK VISELSGK---------------------------------------------------- -----------------------------------------------YHGKGVSNAVANV NNIIAPALVFDLGKQREMDNIMLAIDATDNKSKLGANAILGVSLAICKAGAAQKGVPLYR HIADLAGNKELVLPVPALNVINGGSHAGNRLAMQEFMILPTGASSFTEAMRMGSETYHHL KKVIKAKYGQDACNVGDEGGFAPNIQSNNEALELLKLAIEKAGYTGKIEIGMDIA----- ----------------WLSSDQLLEVYKGFVRDYPVVTIEDSYDQDDWEAWGKMNAIQLV GDDLLVTNPKRVKDAIDKKTCNALLLKVNQIGSVTESIDACKMSQDAGWGVMVSHRSGET EDTFIADLVVGLCTGQIKTGAPCRSERL---------------------------GGPPT AGAFKSRPAQPTNFRKFYERGDFPIALEHDTKGNKIAWKVEIEKLDYHHYLPLFFDGLRE TEHPYEFFARQGVHDMLEHGGAKILPVIPQLIIPIKNALSTRNHLVMCVTLKVLQHLVVS ADMVGESLVPYYRQILPVLNIFKSKNLNSGDGIDYSQQKRENLGDLIQETLEAFEKEGGE DAFINIKYMIPTYESCL------------------------------------------- ---------------AGNKNPHPLESKIIVRVQTDSDYSPQEALTNAMTDLISEVSLLEE RFKESVREKQEGDDDHRRKWDTEEFERLAQEKSDAEKRSKEPPVKRELLKPRDYKVDLDS KLGKSQVITKTTPASGQGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRIERSSLD QVKQRFEMNKKKKDDRDREYDFEERVRELKEEEEKHKAYKKEKRKALKRKAEAEEGNDDM AALMGFSGFGTSKKMGCTMSAEERSAMERSKQIERNLKEDGIQAAKDIKLLLLGAGESGK STIVKQMKIIHEGGFTNEDNKQFKPVVYSNTIQSLVAIIRAMGTLNIAFGDADRESDAKM VLDVIARMEDTEPFSEELLAAMKRLWADAGVQECFGRSNEYQLNDSAKYFLDDLDRLGQK DYMPTEQDILRTRVKTTGIVEVHFHFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCV AMSEYDQVLHEDETTNRMQESLKLFDSICNNKWFTDTSDEKIKKSPLTICFPEYTGKQTY DDAAAYIQAQFEAKNKSTTKEIYCHQTCATDTNNIQFVFDAVTDVIIANNLRGCGLYYHS SFVNPPQTVGNMALLPLRTQFKGPAFDIIDEALHFFKANVFFRNYEIKGEADRTLIYLTL YITECLKKLQRCTSKNQGLKEMHSLAIQRFFLPGESQFPLNAMYHRPSSRAEEDTMRNYL TQVRQETGVRVVEKVFDPVTDKPSKWWMCFAKRRFMDKSLSAPGQAGPYNYSYIFKYIII GDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVAGQKIKLQIWDTAGQERFRAVT RSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIFLIGNKCDLEAQRDVTYE EAKQFAEENGLMFLECSAKTGENVEEAFLDTARKIYQNIQDGSLDLNAAESGVQHKPSAP RNPISNDTQQNTGGCACMSLKAVCVMRDGEVKGTVNLTQEKAVTVAGEITGLTPGQHGFH IHEFGDNTNGCISAGSHYNPHGKEHGAPTDEVRHVGDLGNVTADKFSITDSQVSLTGAYS VVGRTVVVHADVDDLGKGGHELSKTTGNAGGRLACGVIGITKMVNFTVDEIREIMDKKRN IRNMSVIAHVDHGKSTLTDSLISKAGIIAGAKAGETRFTDTRKDEQERCITIKSTAVSMY YKLNEDDVEMGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQA IAERIKPVLFMNKMDLAILTLQLGSEEMYQTFQRIVENVNVIIATYGDEDGPMGEIMVQP YRGTVGFGAALHGWGFTLKQFAAKYASKFKVDSGKMMKRLWGDQFYHYVRGFNQYVLDPI LKVFEVTMPQQDTFNLCEKLGIKLTVEEKEKHEKQLMKVVMRKWLPAGEALLEMITFHLP SPVTAQKYRTDLLYEGPNDDEVAVSMRNCNVKGPLMMYVSKMVPTSDKGRFYAFGRVFSG TVATGLKCRIMGPNYQPIKSIQRTILMMGRYIEPIEDVPCGNICGLVGVDQYLIKTGTIS TFEGAHNLKVMKFSVSPVVRVAVECKNASDLPKLVEGLKRLAKSDPMVQCTMEESGEHIV AGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETVSDESDRTCLSKSPNKHNRLFMRA VNMPDKLADDIEDGKVTPRQEVKERARYLAEHYDYDVTEARKIWCFGPDGTGPNVVMDVT KGVQYLNEIKDSVVAGFQWATKEGVLCEENMRGVRFNVHDVTLHADAIHRGGGQIIPTTR RVLYASVLTAQPRILEPVYLVEIQCPESSIGGIHSVLSTRRGHVTDQQEVIGTPMFQVKA DLPVNESFGFTESLRSATQGQAFPQCVFDHWQLLVVKECRARKGLKEGVPSLENYLDKLM LPLSLLKTAINHPMLVELKNGETYNGHLVNCDNWMNINLREVICTSRDGDRFWRMPECYI RGSTIKYMRIPDEVIDMVKEEQM-KPKGRGDPRARGRGMPQRGGFGSRGRSRGGGNKPGG RGG--------------------------------------------------------- ---------------------------ETVVGSHDGPIRCVEYCPDVNVVVTGSWDSSVK LWDPRTNGNAGSFTQPQKVYTMSVCGDKLVVGTAGRKVLVWDLRNMGYVQQRRESSLKYQ TRCIRTFPNKQGYVLSSIEGRVAVEYLDPSPDVQKKKYAFKCHRIKENEVENIYPVNAIS FHSSYQTFATGGSDGFVNVWDGFNKKRLCQFHRYPSSIASLSFSHDGALLAIASSYMNEQ GLTEDAIYIRRVSDQETKPKMDFQHRAGGKTGVGGVASASETNRDRRERLRQLALETIDL NKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQANLARRAAKEAKEAPAQPAPE KARVDIKKFVKIGRPGY------------------------------------------- ----------------------------DKDNNKFWTHWNKETKQFFLQFAFKHDPKSLP PPPPTPVPPPPM--------------------------------------QFKEQFGDKP SERRPARSDLIVLVAHNDDPTDQMFVFFPDETKVGIKFIKTYCQRMQEENIHRAIIVVQN GMTPSAKQSLTDMAPKYILEQFLEAELLVNITEHQLVPEHVIMTPEEKKELLLRYKLKES QLPRIQQNDPVARYFGLKRGHIVKIIRPSETAGRYITYRLLVKAKDDVGTVIGIDLGTTY SCVGIFKNGRVEIIANDQGNRITPSYVAFTPEGDRLIGDSAKNQLTSNPENTVFDAKRLI GRRWNEPAVQSDIKHFPFTVINKNDKPHVEVSVKGKKTIFAPEEISAMVLIKMKETAEAY LGKEVTHAVVTVPAYFNDAQRQATKDAGVIAGLNVMRIINEPTAAAIAYGLDKKEGEKNI LVFDLGGGTFDVTLLTIDNGVFEVLSTNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRK NNRSVQKLRREVEKAKRTLSSQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMK PVQKVIEDSDLGKNEVDEIVLVGGSTRIPKVQQLVKEFFGGKEPSRGINPDEAVAYGAAV QAGVLSGVEETDGLVLLDVNPLTMGIETVGGVMTKLIGRNTVIPTKKSQIFSTAADNQPT VTIQVFEGERPMTKDNHLLGKFDLTGIPPAPRGVPQIEVTFEIDVDGILRVSAEDKGTGI KNNIVINNDQNRLSKDDIERMINDAEKFADDDKKLKERVESRNELESYAYSLKNQVGDKE KLGGKLSDEDKETITKAVEEQIEWLEANQDAEAEDYQEHKKALESIVQPIVGKLYEGAPP PQEDQEKDELGDEVEDPELEAIKARVREMEEEAEKLKEMQSEVDKQLSQEEKLDADGRSV YVGNVDYGATAEELEQHFHGCGSINRVTILCDKFTGHPKGFAYIEFADKDSITTSLALDE SLFRGRQIKVVPKRTNRPGLSTTDRPPRGGGRRGRMRGAYVGYYQRPRGR---------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------KYDKDVEQKQKELDILKASKA KDLERLKELTKLYAEYEQVVVEDRIEKEKARRKAEQEAEELRAAIRIQSWFRGVMVRKGL GPYSKKKKKKPSVGINGFGRIGRLVLRAALREVNVVAVNDPFIPLDYMVYMFKYDSTHGR FQGDVKLVVDGRAIEVFQMRNPEEIPWGKVGANYVVESTGVFTTIEKANAHIKGGAKKVI ISAPSADAPMFVMGVNHEKYDPSMNIISNASCTTNCLAPVAKVVNDNFGIEEALMTTVHA YTATQKTVDGPSAKAWRDGRTAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPVPDV SVVDLTCRLKKGASYDEIKAAMKGPLKGVLMYTEDQVVSSDFIGEKNSSIFDALAGIALS PTFVKLIAWYDNEFGYSCRVVDLIRYCYGRDKDDLATAILRKKAKPNRLLVEEAINEDNS VVSLSQAKMDELQLFRGDTVLLKGKRRRETVCIVLSDDTVTDDKIRINRCVRNNLRVRLG DIVSIQACPDVKYGKRVHILPIDDTVEGLTGNLFEVYLKPYFLEAYRPVHKGDIFLVRGG MRGVEFKVIETDPSPYCIVAPDTVIHCEGEPVKREEEEEALNEVGYDDIGGCRKQLAQIK EMVELPLRHPQLFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSK LAGESESNLRKAFEEAEKNSPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQ RSHVIVMAATNRPNSVDGALRRFGRFDREVDIGIPDATGRLEILRIHTKNMKLADDVDLE TVAAETHGHVGADLAALCSEAALQQIREKMDLIDLDDDNIDAEVLDSLAVSQEDFRWALS KSNPSALRETAVEVPSVTWEDIGGLEGVKKELQELVQYPVEHPDKYLKFGMTPSKGVLFY GPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFD ELDSIAKARGGNVGDGGGAADRVINQLLTEMDGMTSKKNVFIIGATNRPDIIDPAILRPG RLDQLIYIPLPDLESRVSILKANLRKSPVAPDVDQRYLANITEGFSGADLTEICQRACKM AIRESIEEEIRREKQRADNPDDFDPVPEISRAHFEESMKYARRSVSQNDIRKYEMFKSTL QQSRGFGQGSSTGFGQTAFS----NHNPMKDVEVASPPDDSVSSLAFSPAVIPSTFLVAG SWDNNVRCWEVQSNGQTVPKAQQTHTGPVLDVCWSDDGTKVFTASCDKTAKMWDLNSNQA MQVAQHDAPVKCVSWIKAPSYSCIMTASWDKTLKFWDTRTPNPMMTIQLPERAYCADVLY PMAVVGTAGRGVIIYQLENQPQEFKRIESPLKYQHR------------------------ -----VNPQNPKDNFTFKCHRAGYQDIYAVNSISFHPVHGTLSTVGSDGRFSFWDKDART KLKTSDQLDQPITASTFNAQGNIFAYASSYDWSKGHEGFDPQKMKPHIMLRSCFD----- ---MSSPSAGKRRMDTDVVKLIESKHEVTIVGGLNEFTVKFSGPKGTPYEGGVWKVRVDL PDKYPFKSPSIGFMNRIYHPNIDEVSGTVCLDVINQAWSAMFDLVNVFESFLPQLLTYPN PIDPLNGEAASLYLHKPEEYKNKVSEYVRKYATAEALREQ-----------------MED QDVLTTLKILIIGESGVGKSSLLLRFTDDTFDPEQSATIGVDFKVKTLTVDGNRAKLAIW DTAGQERFRTLTPSYYRGAQGCILVYDVCSKPSFQKLDQWLNELETFATKHDIVKMLVGN KIDMDKREVSRDEGLKFARKHQMLFIEASARTREGVQCAFEELVEKIIQTPGLWETDGLS LGSVIWSIINGSFCSFKVRTKTQKFCRNEFNLTGLCSRASCPLANSQYATIREEKGICYL YMKTVERAAFPSKLWEKVKLSRNYEKALQQIDQNLIYWPGFIKHKCKQRFTKITQYLIRM RKLRLRTQKKLVPLSRKV---ESRREEKALIAAQLENAIEKELLERLKKGTYGDIYNFPQ HAFDKAVEEEEMSEEDESEAEVEYIAEDEFEESDISDMELLQGRFVAQPRMKTFKVYRYD PDKPGDKPHVQEYQVDLNECGPMVLDALIKIKNEIDPTLTFRRSCREGICGSCSMNINGG NTLACLAKIDGNTSKASKIYPLPHMYVIKDLVPDMNNFYAQYKFIEPYLKKKGIKEEDYG KKSYMQSPDDRAKLDGMYECIMCACCSTSCPSYWWNGDKYLGPAVIMQAYRWVMDSRDDY KQERLDNLRDKWSVYRCHTIMNCTKTCPKGLNPGAAVAELKKIMMGQESKGIPRQDVRPG HTIYINNLNEKIKKEELKKSLYAIFSQFGQILDIIAMKGIKXE---WVIFKDISSATNAL RSMQGFPFYDKPMRIQYSKKESDVIAKMKGTFVERPKK---------------------- -------------------------------VRLVPGRHDIAFVEFENEVQAGAAKDALQ GFKITPDNAMKISFAKK------------------------------------------- -------------------------------------------------------NVDPK NCKLLLTEPPMNPMKNRERMIETMFEHYQFDGLYIAIQAVLTLYAQGLLTGVVVDSGDGV THICPVYEGFALPHLTRRLDIAGRDITRHLIKLLLLRGYAFNHS--XXXXXXMKEQLCYV GYDIEQEQKLALETTVLVEQYTLPDGRVIKVGGERFEAPEALFQPHLINVEGVGIAELLF N---XXDMDTRVEFYKHIVLSGGSTMYPGLPSRLEREIKQLYLERILKGDTEKLAKFKIR IEDPPRRKHMVFLGGAVLADIMKDKDTFWISRQEYQEQGLRCLSKLGVS----VGKPIEC KAAVAWEAKAPLSIETITVAPPQKGEVRIKVLYTGVCHTDAYTLGGLDSEGKFPIVLGHE GGGIVESIGEGVTSVKPGDHVVPLYIPQCRECKFCKSPKTNLCSVVRSTQGNGVMPDGTS RFTCKGQTLWHFMGTSTFSEYTVAAEISVAKVDEKAPLDKVCLLGCGISTGYGAALNTAK VEKGSNCAVWGLGAVGLAVVMGCKAAGASRIIGVDLNPEKFEIAKKFGATECVNPKDFDK PIQEVLVGMTDGGLDYTFECVGNVHTMRAALEACHKGWGESIIIGVAAAGQEISTRPFQL VTGRVWKGSAFGGWKSRDSVPKLVEDYMSGKMMVDEFVTHTMPLEKINEAFDLMHSGKSM DSYDVIANQPVVIDNGSGVIKAGFAGDQVPKYHFPNYIGRPKHVRCMAGALEGDMFIGPK AEEHRGLLTIRYPMEHGIVTDWNDMERIWQYIYSKDQLQIFSEEHPVLLTEAPLNPRRNR EKAAELFFENFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIM RVDIAGRDVTRYLQLLLRKEGHKFHTTAEFEIVKTIKERSCYLSINPQKEESMEAEKTQY TLPDGSILDVGPARFRAPELLFRPDLIGEECEGIHEVLAYAIQKSDMDLRRTLFANIVLS GGSTLFKGFGDRLLSEVKKLAPKDIKIRISAPQERLYSTWIGGSILAALDTFKKMWVSKR EYEDEGQRAILRKTF---KIAKVVVHPLVLLSVVDHFNRMGKVGNVKRVVGVLLGSNRNG VLDVSNSCAVPFDEDDKDKSVWFLDHDYLENMAGMFKKVNAREKIVGWYHTGPKLHQNDV RINELLRRYCPNSVLVIIDAKPKDLGLPTEAYIAVEEVHDDGTPTTKTFDHVPSEIGAEE AEEVGVEHLLRDIKDTTVGSLSQRITNQLQGLRGLHSQLSDIHSYLQKVSSGQLPINHAV IYQLQDVFNLLPDINFQEFVKAVYVSTNDQHLVLYLSALIRSIIALHNLINNKISNRDAE RNEAKKQEMGLLFSKLWGLFTNEEHKVIIVGLDNAGKTTILYQFLMNEVVHTSPTIGSNV EEVIWKNIHFIVWDIGGQESLRAAWNTYYANTEFVIVVVDSTDRERLSITKEELYSMLAH EDLRKAAVLVFANKQDLKGAMTAAEISQQLNLTSIKEHPWHIQACCALTGEGLYEGLSWI SSHIRR--IPTRNVIVTDPSQLPHDYGTTPGGTLFSTTPGGTRIIYERSFLMKCRNSPLA KSPPANIPDLPGLLR-------KEIYKYEAPWTVYSMNWSIRPDKRFRLALGSFVEEYNN KVQIVSLDEETSEFVARSTFDHPYPTTKIMWIPDTKGVSPDLLATSGDYLRVWRVTRLEC LLNNNKNSDFCAPLTSFDWNEVDPNLLGTSSIDTTCTIWGLETGQALGLVSGHVKTQLIA HDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLSWNKQ DPNYLATMAMDALEVIILDVRVPCTPVGRLSNHRACVNCFTWAPHSSCHLSTAADDHQAL IWDIQQMPRAIEDPILAYTAGGEINQIQWSSTQPDWISICYNNCMEILRVRTFSTSSKVA VLGAAGGIGQPMSLLLKLNPRISHLSLFDIVHTPGVAADLSHCSTPAKVTGHLGTETLRE CLEGCQVVVIPAGVPRKPGMTRDDLFNTNASIVRDLSDACAQYCPDAMVCIISNPVNSTV PIASEVYKMRGVYNPNKIFGVTTLDIVRANTFIAEAKGIDVNQVTCPVVGGHSGVTIVPL ISQCTPPVSFPTEERNKLSVRIQNAGTEVVEAKAGAGSATLSMAYAGTRYVNSVLQALDG DEGIIECSYVRSDETEAKYFSTPILLGKNGIEKNLGLGKLLDYEVNLIKAAMPELIKNIQ KGEDFVANN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------LLKKSHIDLLKEREYNSYSWQDLV ASGVVEYIDTMEEETVMLAMTPDYLLEKNRVYCSTYTHCEIHPAMILGVCASIIPFPDHN QSPRNTYQSAMGKQAMGVYITNFHVRMDTLANVLFYPQKPLVATRAMDYLKFRELPAGIN CIVAIASYTGYNQEDSVILNESAVDRGLFRSIFYRSYKDQESKKGMDQEELFEKPERQFV QGMRHAVYDKLDDDGIIAPGVRVSGDDVLIGKTLTLPDNEDELEGQAKRFTKRDCSVFMR RSETGIVDQVMVTINQEGYKFCKIRVRTVKTPQIGDKFASRHGQKGTCGIRYRQEDMPFT NEGLTPDIIINPHAVPSRMTIGHLIECLQGKVSANKGEIGDATPFNDTVNVQKVSSLLHE YGYHLRGNEVLFNGHTGRKLNAQVYLGPTYYQRLKHMVDDKIHSRARGPVQILNRQPMEG RSRDGGLRFGEMERDCQIAHGAAQFLRERLFEISDPYRVHVCNLCGLIAIANLRNNTFEC RGCKNKTQISQVKMPYACKLLFQELMSMSIAPRMM--------GFSFDNCKRNAKLQKGL KAPKVYKTGTTICGIIFKDGVVLGADTRATEDTIVADKNCAKIHYIAPNIYCCGAGTAAD TEVTTNMISSKLELHRLDTGRNARVCAANRLLKQFLFRYQGHISAALVLGGVDSKGPHLY SVWPHGSTDKLPYVTMGSGSLAAMATFEDGFRPNMERDEAMQLVRNAIAAGIFNDLGSGS YVDLCVITKKVDYIRPFDEANEKGKRQGSYRYKIGTTPVLTKDVKKIEFDVT---VTFKV TLTSDPKLPYKVMSVPESTPFTAVLKFAAEEFKVPPATSAIITNDGIGINPSQSAGNVFL KHGSELRLIPRDRVGY--------------------IFFVIYHIIAFDELKTDYKNPIDQ CNSLNPLVLPEYLLHILYNVLFLLAGCWGTLVLNVPLIAYHVRRYLNRPVMREPGLYDPT TIMNQDELSRAQKEGWIKLAFYLLSFFYYLYSMIYELVSSMGLLTILKKMKQKEKEVRLL MLGLDNAGKTTIVKKFNGEDIDTISPTLGFNIKTLEHKGFKLNIWDVGGQKSLRSYWRNY FESTDGLIWVVDSADRRRLNDCRGELDSLLLEERLAGATLLVFANKQDLPGALPSEEIKK LLDLDSIKSHHWMITGCSAVTGENLLAGIDWIIDDIASRIFTMDHSKKKVCYYYDGDVGN YYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATQEEMTKFHSDDYIKFLRSIRP DNMSEYNKQMQRFNVGEDCPVFDGLYEFCQLSTGGSVAGAVKLNKQATDIAVNWSGGLHH AKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY GEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDDSYEQIFQPVIAKVMEMYQPSAIVLQC GADSLSGDRLGCFNLTLKGHGKCVEFMKKYNLPLLVLGGGGYTIRNVARCWTHETAVALG CEIANELPYNDYFEYYGPDFKLHISPSNMANQNTPEYLDKIKTRLFENLRMLPHAPGVQM QDVPEDAVKEENNPDERISIRASDKRIACEEDFSDSEDEGEGGRRNRESYKSRKRDNKNF ECNICLDTAKDAVISMCGHLFCWPCLHQWLETRPTRQVCPVCKAGISKDKVIPLYGRGSD NQQDPREKVPPRPQGQRQEPENNTNFNGFGFGFQMSFGIGAFPFGFFASNFNLNDGR--- -------HSEEQLLSRVFLWVAVLFMFWLMIA---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------LEGHAMPIRGLCFSPDSQFLVTASDDGHIKI YDVQHANLAGTLSGHGSWVLNVNFSPDNIHFTSCSSDKTVKVWDAGSRQCVHTFYDHLDQ VWCAKYNGAGNRIVSVSEDRAVHVYDCPIETDDEFDNRYENYFNRQDIDGWELRKAINDL QGYDLVPEPRIVSAALRACRRVNDYALAVRYLEAVQDKAGPHKAAIWPYMLQELKPTIEE LGILTPEEMGYDKPELATKDVYDI------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------YESQTGHCVHLRGLPFAAKDQDILDFFKPLNPVNVAVH YNNGRASGEADVDFATHEEAKEAMRKDRGTMQHRYIELFYKDKEKPTEIRYSNITAAKAV ANAIRTSLGPRGMDKMIQTGTGDVTITNDGATILKQMQVLHPAAKMLVELSKAQDVEAGD GTTSVCVIAGSLLEAAQKLLQKGIHPTTISESFQRAAKKCCEFLAEMSTPVELSDRESLL KSATTSLNSKVVSQYSSLLSPMCVDAVMRVIDPAVDTNVDLRDIKIIRKLGGTVEDTELI DGLVFSQRTAGSGGPNKVEKAKIGLIQFCISPPKTDMDNQVVVSDYTQMDRVLREERQYI LNIVKQIKKSGCNVLLIQKSILRDAINDLALHFLAKMKIMVLKDIEREDIEFVCKTLDCR PAASLDHFTAECLGSADLVEEVQTGDSKIVKMTGIANAGKTVSIVVRGSNKLVLEEAERS IHDALCVIRCLVKNRALIAGGGAPETELSLRLMHYANSVTGVEQYCLRQFAEALEIIPFT L--------------------------------------------------TSAIHLASE TVRSILKIDDIVNCMMILLEINNRIIEETLTAKFNNALQGNKPDLVDITAADFDGVLYHI SNPTDDKSKLRVSISLKFYKDLQEHGADDLINREYGPFLTAVEDG--------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------X XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------ISDDDRIF TNLYGRHDWKLKGAQQRGDWYKTKEIILKGTEWIQGEIKASGLRXXXXXGFPTGMKWSFM NRPDDGRPKYLVVNADEGEPGTCKDREIMRHDPHKLVEGCLVAGSAMGARAAYIYIRGEF YNEASNMQVAIREAYDAGLLGKNACGSGYDFDVYMHRGAGAYICGEETSLIESLEGKAGK PRLKPPFPADVGVFGCPTTVNNVETIAVAPTICRRGAEWFSSFGRQRNQDVMMDFDALVQ AQSGLGTAALIVMNKQADVVRCISRLMEFYKHESCGQCTPCREGVNWMNTILKRFVKGNA RVDEIDMLWEISKQVEGHTIC--------------------------------FTQEQVD EMNQQLNQTRSQRVRAAMFPETLEEGIQIPSTQIHPDQPTAVQRLAEPSQMLKHAVVNLI NYQDDADLAQRAIPELTKLLNDEDQVVVSQATMMVHQLSKKEASRHAIMNSPQMVAALVR AMNNTNDLETTRCAAGTLHNLSHHRQGLLAIFKSGGIPALVKLLSSPVESVLFYAITTLH NLLLHQEGSKMAVRLAGGLQKMVALLQRNNVKFLAITTDCLQILAYGNQESKLIVLASGG PAELVRIMRSYTYEKLLWTTSRVLKVLSVCASNKPAVVEAGGMQALGMHLGHQSTRLVQN CLWTLRNLSDAATKCDNMEGLLQMLTQLLSSNDINIVTCAAGIMSNLTCNNQRNKVIVCQ VNGIEALVRTIMQAGDREDITEPSVCALRHLTSRHPESEMAQNAVRLHYGLPVIVKLLHP PSRWPLIKAVIGLIRNLALCPANHAPLREHGAIPRIVQLLIRAHQDTQRNRGTYVDGVRM EEIVEGTVGALHILAREAHNRAVIRGLNTIPLFVQLLYNPIENIQRVAAGVLCELAADKE GAEIIEQEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRGE NXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXDEPYYCSQQIQIPPELPDILKQFTKSAIRTQPKDVLAWSAAYFRSLANGETPP VKERLEMPVATQKTDTGLTPGLLRVLNKQLGPKKNVPLSLIEEKWTDLALPKEQFDELIR IGSFSGEVEWLKFFALGCSALGENITAAMKTVCEILTADPDGGPARIPFKLFTDLYTYLA GIDGEITGEHINLVTTYLQYHVDKQDGMVQPRNFLGPDCPNLA-KSDSANKEHMMEQVKA QIAVANAQELLQKMTDKCFKKCIVKPGTSLDNSDQKCVAMCMDRYMDAWNLVSRSYTQRL QQERNKMMNRLFGRSKAKGPAPNLNDCISNIDSRGESVEKKISKLDQELAKYREQMKKMR DGPSKNMVKQKAMRVLKQKKMYENQSEQLRNQSFNLEQTNFGIQSLKDTKTTVDAMKVGV KEFKKEYKHINIDNIEDLQDQLEDMTEQSNEIQEIMGRSYGMPEIDDDELEAELDALGDD LAFDEDSSYLDDAITAPSAPTNVPG-DSATNKDGVPVDEFGLPQIPAQXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIDDED DDFVGMGMDPEPSSKHDGEDYPFDVLTADEIVKHMVDCIKEVNSVIQIPATTTRILLNHF KWDKEKLMECYYDGNQDKLFSEAHVISPFKRSLELICEICFLAMPTRMTGLECGHRFCSE CWTEYLTTKIMDEGMGQTIACAAHGCDILVDDATVMTLVTDPKVKLKYQHLITNSFVECN RLLRWCPKPDCGHVVKVHYYDSKPVTCACSHVFCFACGENWHDPVKCIWLKKWIKKCDDD SETSNWIAANTKECPKCHSTIEKDGGCNHMVCKKCRFDFCWVCLGPWEPHGSSWYNCNRY DEDDAKKARDSQEKSRSALQRYLFYCNRYMNHMQSLKFESKLYASIKIKMEEMQQHNMSW IEVQFLKKAVDVLCQCRQTLMFTYVFAFYLKKNNQSIIFEDNQKDLEQATEELSEYLERD ITSDMLVDIKQKVQDKYRYCESRRTKALDHVHEGYEKDTWDYQDMATTDGKLNTTERAVK TVPFPPSHRLTMPEVFDQKGKPRPEALKQHFILEGRVTEDVALRLINEGAVLLRQEKTMI DIEAPVTVCGDIHGQFYDLMKLFEVGGSPATTRYLFLGDYVDRGYFSITEHVYDACMEAF DCLPLAALMNQQFLCVHGGLSPEIHTLDDIRKLDRFKEPPAFGPMCDLLWSDPLEDFGNE KTTEHFTHNSVRGCSYFYSYAACCDFLQQNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSL ITIFSAPNYLDVYNNKAAILKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVT EMLVNVLNICSDDELMTEGDEQFEGDVAARKEIIRNKIRAIGKMARVFQVLREESESVLQ LKGLTPNGLLPIGALSGGKDSIRTAMSGFSPTHKISGFDEAKYLDKMNERMPPHKXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMDKNKLNDLVGRLQKGGKGAGVGLGFLAA AGAVGYGLLQSMYTVEGGHRAIIFNRVGGIGDNIYREGLHFRIPWFQYPIIYDIRARPRK ISSPTGSKDLQMVNISLRVLSRPDQLRLPQMYRQLGTDYDERVLPSICNEVLKSVVAKFN ASQLITQRQQVSLMVRKELIDRARDFNIILDDVAITELAFGKEYTAAVESKQVAQQEAQR AFFIVEKAKQEKQQKIVQAEGEAAAAKMIGESIAVNPGYLKLRKIRAAQSIARTIAASRN RSYLNANSLMLNINSEDFDNTLD------------------------------------- ------------------------------------------------------------ ------------------GLSMYAWKGESEEDFWWCIDKCISSDNWQPNMILDDGGDATH LMLKKYPAMFSMVKGIVEESVTGVHRLYQLSKSNQLTVPAMNVNDSVTKTKFDNLYTCRE SILDALKRTTDVMFGGKQVLICGYGEVGKGCASALKGMGATVMVTEIDPICALQAIMDGF RVVTLNEVIRTVDVIITCTGNKHVVTRAHMDKVRNGCVICNMGHSNMEIDVNSLRTHDLT WERVRSQVDHVIWPDGKRIVLLAEGRLVNLSCSSIPSFVVSITAATQALALIELYNAPNG RYKQDVYLLPKKMDEYVASLHLPAFDAHLTELTDDQARYLGINKAGPFKPNYYRYPDPDA IKMFVGQVPRSMDENDLRKMFEDFGPVFQLNVLRDKVTGQSKGCCFVTFYTRKSALEAQN ALHNIKTMPGMQHPIQMKPADSEKRS-EERKLFIGMLSKKCTENDVRMMFSPFGQIEELT VLREQNGQSKGCAFVTYAQKQCAQNAIKSMHHSQTMEGCRLPLVVKFADTQKEKEMKKLQ QANNALHIQFIGGIAGGTASVYVGQSLDTVKVKMQTFPNLYKNAYDCFTRTLREEGVRGL YAGTVPSLENAVLFMAYGMCQRALASAAFFSSLVLCPTELIKCQLQALTKHIVRSEGVRG LFRGLVPTFAREMPGYFFFFGGYEVTRYLLTPPGKTKEDIGPKTMFCGGMGGAALWIAVF PADVIKSRAQI--------------------------------------GGGNEFTRLTQ SIGNNLQKITQNVSQMQRLVQQIGTSQDTPELRDKLHQIQHYTNQLAKDTNKYMKDLSHI PSETRQRKMQKERLMNEFSQTLNKFQAAQRQAAQKEKESVEDVDLQLLTERENAIKQLES DIMDVNQIFKDLGVLVHEQGEIIDSIEANVETVQVDQGTQQLAKAHTYQSKARKKKCIII VVLVVVIAIIVTILAVTLSMVNVMKGVLVECDPAMKQFLLHLDDTNALGRKFVVQDLDDT HIFISADIIETLQNRIDDLMDKLHF-------------EAERNLRETEEMLQKKADFLEK KVEQELGTARKRVALAALKRKKRFEKQLQQIDGTLSTIEFQREALENASTNTEVFKVMGD SAKALKKAHQNMDVDDVHDMMDEIAEQHEIANEIGEAISNPVGFSQDLDEDDLL--XXXX EQEQLDEQLLDIGNLPSVPVSEDDEMAELEAWASFMQRFHNRVRQILMASGSTTFTKIVN KWNTALIGLMTYFREAVVNTQELLDLLVKCENKIQTRIKIGLNSKMPSRFPPVVFYTPKE LGGLGMLSMGHVLIPQSDLRWSKQTDVGITHFRSGMSHDEDQLIPNLYRYIMPWESEFID SQRVWAEYALRTDMIQALGGVEGILEHTLFKGTYFPTWEGLFWEKASGFEESMKYKKLTN A----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ASYQASRKNLAINKNTKVICQGFTGKQGTYHSQQAI DYGTNMVGGVTPGRGGKTHLGLPVFDNVKDARAATGAEASVIYVPPAFCYKAIEDAIDAE IGLIVVITEGIPQQDMVRAKHKLLRQDKSRLIGPNCPGIIKPGECKLGIMPGHIHKQGKI GIVSRSGTLTYEAVHQTTQVGLGQSLCVGIGGDPFNGTNFIDCLEVFLNDPETEGIXXXX XXGGQAEERAAEYLAENNGPNSKPVASFIAGVTAPPGRRMGHAGAIIAGGKGGAEEKIEA LTQAGVHVTRSPAQMGTTILKAMQDAGKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFTRFVEVGRVGYVA FGPDEGKLVAIIDCITQNSVLVDGP--GMERKSMNLKMIHLTKFVLISFGCRPGVVKKAW EKAEIEKKWAETTWAKKIAARKLRANLSDFDRFKLMKAKQARNRLIQSEFGRLQAKAKKT CPLLLRVFYNNGRHHNINEYARGNTPATELQIYTWMDATLKELTSLVKEVNADARKKGTF FDFAITYPDSRTPTYRMRDIGTTCAGRKGADDNATLASKRFQ------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------FNSADDFDAWFNANSCLENQQLVERLHEVLRPFL LRRLKSDVEKRLLPKKETKIYMGLSKMQREWYTKILMKDIDVVNGAGKSDKMRLMNILMQ LRKCCNHPYLFDGAEPGPPYTTDKHLVDNCGKLVLLDKLLPKLKSQDSRVLIFSQMTRVL DILEDYCVWRNFNYCRMDGQTPHEERQESIDAFNAPNSEKFVFMLSTRAGGLGINLNTAD IVVIYDSDWNPQMDLQAMDRAHRIGQ-QQVHVFRFITESTVEERIVERAEMKLKLDNVVI QQGRLVDAATTKEVLSIIRHGADQVFASKDSTIGDEEIDIILAKGQKKTEELNKKLDGLN ENSLRGFAMETP------------------------------------------------ ---------------------FFPPRLFELLDCEIYHYRKTIGYRVPKDPDLGSDAERVR KEEQKKIDEAELLTEEELAEKEELLKGFTSWNKRDFNQFIKANEKYGRDDLDSISKEVEG KTPEEVMEYASVFWERCNELQDIERIMSQIERGEAKIQRRISIKKALDAKMARYKAPFHQ LRIQYGTNKGKNYTEEEDRFLICMLHKLGFDKENVYDELRAAVRQAPQFRFDWFIKSRTA MEIQRRCNTLITLIERENMELEEREKAEKKK----------------------------- ------------------------------------------------------------ --------------------------------------------PADETDGGGSKYVPPS MRDGGNKRGESMSADELATIRVTNLSEDTRESDLQELFRPFGAISRIYLAKDKNTGQSKG FAFINFVKREDAARAIAGVSGFGYDHLILNVEWAKPSMSETYDFLFKFLVIGSAGTGKSC ILHQFIEGKFKNDSNHTIGVEFGSKVVNVGGKSVKLQIWDTAGQERFRSVTRSYYRGAAG ALLVYDITSRETYNALTNWLTDARTLASPNIVIILVGNKKDLEAEREVTFLEASRFAQEN ELIFMETSALTGENVEETFLKCSRSILTKIESGELDPERMGSGIQYGDASLRRLQSRRPD CAC-IESSSKQNLDTSLWPLLLKNFDKLNVRTAHYTPIASGCSPLQRPIQDYVKAGFINL DKPANPSSHEVVAWIKRILRVEKTGHSGTLDPKVTGCLIVCIDRATRLVKSQQSAGKEYV CIFRLHSAVESLARLNQCVETLTGALFQRPPLISAVKRQLRVRTIYESKLLEYDEEKNMG ILWVSCEAGTYIRTLCVHLGLMLGVGGQMQELRRVRSGIQSEKEGLVTMHDVMDAQWVYD HQKDEGYLRRVIKPLEALLTSHKRIIIKDSAVNAICYGAKMMLPGVLRYDDGIEVNDEIV MVTTKGEAVALGIAMMTTAVIATCDHGLVAKIKRVIMERDTYPRKWGLGPVALKKKNMIQ QGLLDKHGKTNEKTPADWLQNYMEL-----------------------MADAGFERKKAP KSGQLKTQKAVSAAQRSGVEIDVSKKFSAGSNKQHGTDKNTAKLDRETEELSHQTVGLDV GRLIQQGRQAKKLTQKELATRINEKPQVINDYENARAIPNQAVLTKIERIIGLKLRGKDK GTPL------------VLSQANTGGVLSTLLLNNEGALLAFSGYGDKDARVTAAIASNIW EAFEKNGRSAFNEDQLDFILLECQEGKVAITKVANLLLAIYAKESV-------------- ------------AQATARIQTKKQTLDDAYAPPANFLEIDVVNPEGKKKFTDYEVRMRTN LPVFKVKESSVRRRYSDFDWLRAELERDSKIVVPTLPGKALARQLPFRGDEGLFEEDFIE ERRVGLEGFVNRVAGHPLAQNERCLHMFLLEQNIDKNYVPGKVRTTRQMSARLSEVGVLE TPKLQGKYNTGQLFLHRVFGYRAVVLFPWVGKVYDRDIATKGAKEVKGRTHTYYQVLIDA RDIPHIRVGTESVTFLSNQENGTLYSIPGLDYVGHEDVLPYQTTEKQPIHNHLFEKFLHH DSRFVARDTLQEWQDRNHPWLELTDVHRETTDNIRVTVMPFYIGEVQQTHVYWWRYSIRL ENLGEETVQLRERHWRIFSLSGTLETVRGRGIIGKEPIFSKTQPAFQYTSHVSLQAPSGH MWGTFKMEREDGSFFECRIPPFSLESKRDSDMATSKSANTYNRQNWEESDFPILCQTCLG DNPYIRMTKERYGKECKICARPFTVFRWCPGARMRFKKTEVCQTCSKIKNVCQTCLLDLE YGLPIQVRDAALKIADDLPRSDVNKEYYTQNMEREIANTDGTVAVGGVGKAQATSDMLLK LARTTPYYKRNRPHICSFWVKGECKRGEECPYRHEKPTDPDDPLADQNIKDRFYGQNDPV ADKLMKRYTDMPALEPPEDMDVFIMVRRQKTTIFMDAKESTTILELKKMLQGITKKAPED IRLFKENKNLGDCGFTSSTARAQAPATIGMAFRDFEELSIAPLSTPPELPDVMKPQESGS SHGTEHLLRYHAVLLRARFDENKDLDPVVAKKILEEGEEELFMKSHPQPFKFPSGPGGVA YGRESKIPDWYLDMMHPLERAQYPEYYAKREQRKREFMEAWEKKYGKPE----------- ------------------------------------------------------------ ------------------------------------------------------------ --LLIDSNGVIKLADFGLARAFAIPVRVYTHEVVTLWYRAPEVLLGSHRYSCPVDIWSIG CIFAEMGTKRPLFHGDSEIDQLFRIFRTLSTPTEETWPGVTELPDYKTTFPNWKKQTLQQ SVD------------------------------AARLFNKIGQLGVGLAIAGGVVNTALF NVNGGHRAVIFDRFAGVKQNVIGEGTHFIIPWVQKPIIFDIRAKPSSVPTITGSKDLQNV NITLRVLFRPMAARLPDIYTNLGIDYDERVLPSIINEILKATVAQYDASELIT------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------------EK WFGIRKELAAVRTVCSHIENMIKGVVKGYKYKMRSVYAHFPINIVISQEGTAVEVRNFLG EKFTRKVNMLKGVKIESSGGLKDEFILTGNDIELVSKSAALIQQSTTVKDKDIRKFLDGV YVSEKTTVVEEMGCAVSTDDAAAIERSKAIDKTLRADGEKASREVKLLLLGAGESGKSTI VKQMKIIHEKGYSQEECLQYKPVVYSNTIQSMIAIIRAMGQLKIDFGNPDRTEDARQLFT LAGSADDGELSSELAQIMKRLWKDPGVQECFSRSREYQLNDSAEYYLNSLERMGQRGYIP TEQDVLRTRVKTTGIVETHFSFKGLHFKMFDVGGQRSERKKWIHCFEGVTAIIFIVAMSE YDLTLAEDQEMNRMMESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICFP- ------------------------------------------------------------ -----------------------------------------------AMFFAYNTQLGPP YHILVDTNFINFSIMNKLDIVTSMMDCLYAKCIPYITDCVMAELEKLGSKYRVALRIVKD ERFQRLPCMHKGTYADDCLVQRVKQHKCYIVATCDKDLKRRIRKIPGVPIMYLSQHKYSI ERMPDAFGAP-------------------------------------------------- ---------------------------------------------------------EPM DIDRNIEIPSNKATVLRGHESEVFICAWNPTNDLLASGSGDSTARIWNMNDNSNANQLVL RHCIQRGGTEVPSNKDVTSLDWNCDGQLLATGSYDGFARIWGTDGRLVSTLGQHKGPIFA LKWNKKGNFILSAGVDKTTIIWDASSGHCTQQFAFHSAPALDVDWQSNTSFASCSTDQCI HVCQLESDRPIKTFQGHTNEVNAIKWDPQGNLLASCSDDMSLKIWNMKQDTCVHDLQAHN KEIYTIKWSPTGPGTNNPNAPLILASASFDSTVRLWDVER-------------------- ------------------------------------------------------------ ---ATDDLASLFECPVCFDYALPPIMQCQSGHIVCSNCRAKLNMCPTCRGPLGNIRNLAM EKVAGQVMFPCRYSSSGCAVTLPHTEKPEHEETCEYRPYNCPCPGASCKWQGSLEQVMPH LMQQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGDNFMLVLEKQERYEGQQLFYA IVQLIGTKKQAENFAYRLELNGHRRRLTWEATPRSIHDGVQAAINSSDCLVFDTNIAQLF ADNGNLGINVTINMC-AMNTFQQEYMQMPPITRAYTTACVLTTVAVQLDIITPFQLYFNP DLIFRSYQLWRLVTNFMFFGTIGFNFLFNMIFTYRYCRMLEEGSFRGRTGDFFFMFLFGG ALMTIVVNLVFLGQAFTIMLVYIWSRRNPYVRMNFFGLLNFQAPYLPWVLLGFSLLLGNS IVVDLMGIAIGHIYFFLEDVFPEQPGGFRILKTPNFIKWIFDGPVEDPDYAPPPPGGFEW GQ----------RKDGRTVEQVRPIFLRPGTITKAKGSAYIEMDKTKIICAVYGPREV-- TRRESMKGQLQCHFQYATFSHAHRGQH-MVDDKSREQARLIQQALEPAVMLDKFPKARMD VFITVLENAGSCIAGALTCASVALADAGIEMYDLVLGCSMRQHGDLQLLDPSQEEE---- ---------------------------------------------------MAGSYYFVM VGHMDNPLFEMDFNPPGKANDPKKDDHRHLNQFIAHASLDRVDEYVWTTNNMYLKIVDKF NK--------------------------------------KFSMNPFYEPNSPIRSSAFE KKCIYLGRKFL------------------------------------------------- ---------------------EVNLSEIPEGKNATFKWRNKPLFIRHRTQEEIDREASVE PASLRDQEHDNDRVQNPEWLIIIGVCTHLGCVPIANAGDYGGYYCPCHGSHYDASGRI-- -----------------------MSRQTSRGGDPKKVAGELFTLTYGSLVAQLIKDYEND EEVNKQLDKMGYNIGVRIIEDFLARASVNSCQDFRETADVISKIAFKMYLGVVPVVANWS PAGDEFSLLMENNPLIDFVELPEGHSTLNYSAILCGALRGALEMVQMDVSAWFVQDQLKG DNITELRVKFNKRLEDAIPVGED------------------------------------- ------------------------------------------------------------ ------------------------RIGRFSEAKSRFYGAQIVLVMEYLHHLDVMYRDLKP ENLLIDAQGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVY EMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDMLRNLLQVDLTKRYGNLKNGVN DIKNHKWFATTDWIAVYQRKLEAPFIPKCKGPGDPSNFDDYEEEPLRISSTEKCAKEFAD F-FADTLLILFISVATAFLGEGLTWLLVYRTDKYQKLKAEVEKQSKKLERQKEAIT-GDD RGQKKKIERNEEKLKSNNRDLALVKMKSMFAIGFTFTALLSMFNSIFDGRVVAKLPFTPI SWLHGISHRNLMGTDFTDCSFIFLYIMCTMSIRQNVQKILGFAPSRSASKQGGGFFN-CL KVFDEWTEQDQVDYVETLLSHMCHYQHGQINTYLKPMLQRDFITALPAKGLDHIAENILS YLDAKTLCAAELVCKEWNRVISDGMLWKKLIERTMITDPLWKGLSERRGWGKHMFKGAPG EPPKDNKFYRKLYPQIIKDIERIENNWLTGRHTLQRIHCRSETSKGVYCLQYDDNKIVSG LRDNTIKIWDRHTLDCVQVLTGHTGSVLCLQYDENIIISGSSDSTVRVWSVKTAEMLNTL IHHCEAVLHLRFADGIMVTCSKDRSIAVWDMQSPTDINLRRVLVGHRAAVNVVDFDQKYI VSASGDRTIKVWNTNTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGMCL RVLEGHEELVRCIRFDSKRIISGAYDGKIKVWDLAAALDPRSPPGTLCIRTLVEHSGRVF RLQFDELQIVSSSHDNTILIWDFLE----------------------------------- ----------------------KLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITSSQS FNNIRQWIRNIEEHASTDVEKMVLGNKCDMNDKRQVSKERGEALAVEFGVKFLETSAKTN INVDEAFFTLASDIKAKMDRKLADGETSADRNVEIWKIKKLIKSLEAARGNGTSMISLII PPKDQISRVAKMLADEFGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVIYCGT IVTDEGKEKKVNIDFEPFRPINTSLYLCDNKFHTEALTALLADDNKFGFIVMDGNGALFG VLSGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAETAVTLFITNDKP NVCGLVLAGSADFKTELSQSDMFDPRLQAKILKIVDVSYGGENGFNQAIELSAESLSNVK FIQEKKLIGKYFDEISQDTGKFCFGVDDTLKALEMGSVEILIVWENLDIQRYVLKNHSAD EEKILFLKPEQEKDKTYFVDKDTGVEMELVENIPLLEWFANSYKAFGARLEIITDRSQEG AQFVKGFGGIGGILRYQVDFQSMEPLDDLGDDFNLDDY---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----LSMMLLDQYYRTIKGFEVLIEKEWISFGHKFATRIGHGEDKHSDADRAPIFLQFID CVYQLTHQFPNAFEFNEHFLITILDHLYSNLFGTFLCNTDKERNREDIRHKTVSLWSYVN CQLEEFTNPLYHHVLLPVASLRRIQLWTGYYLRWNPSMRPQEPIHLRNRELLILKAQLQK RVEELQKQVDEK-GPLKPFIPHVPFDLTQCESAFPRTKPVQDEKPFADAVLKRAQELTPT PIEQAAVLNLVTKITAVLDNLVVAPGNFEAAQLEEVRQVGSHKKGTMMQGHNVADVVVIL KTLPTVEAVEVLGKKVVDDMKQAEPQEVLTMLPNDSGFEISSADATVKVLITTIPPNMKK LDPELHLDNKIMQSHLAAIRHARWFEENAFHSSIKVLVRLVRDLRARFEGLQPLTPWIMD LLCHFAIMNNPNRQPLPVHHAFRRVLQL-------------------------------- --------------------------------------------------------VVRL IQQYLKENNLVRTLATLQDETGVSLNTVDSVDSFISDINNGHWDTVLQAIQTLKLPDNKL IDLYEQIVLELIELRELGAARSLLRQTDPMIMMKQQHQDRYVHLENMLARSYFDPREAYS EGQSKERRRAAIAAALSGEVNVVPPSRLLALLSQALKWQQHQGLLPPGTTIDVFRGKAAV KEQEEEKYPTTHNKTIKFGSKSHVECARFSPDGQYLVTGSADGIIEVWNFTTGKIRKDLK YQAQDNYMMMDDAVLCLSFSRDSEMLATGGQDGKIKVWKMTTGQCLRRYEHAHSKGVTSI IFSKDNSQLLSASFDQSVKIHGLKSGKVLKEFRGHGSFVNDAVFAADNHHIISASSDGTI KIWNIKSTECQNTLKSLGGTVGSDITVHSIHPLPRNTEQFVVCN---------------- ------------------------------------------------------------ --------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-- -----------------------------------------------------PVVGEEQ MINYEDFLKVGKEAGPKCKTFFSATSFAKLIQNDAYGRISIMQFFNYVMRKVWLHQTRIG LSLYDVAGQGYLKESDLENYILELIPTLPQLDGLEKSFYSFYVCTAVRKFFFFLDPLRTG KVKIQDVLACGFLDDLLELRDEDLPKDMQESNWFS------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TEVVRGQTFDVGPRYTNLAYIGEGAYGMVVTAMDNATCQ KVAIKKISPFEHQTYCQRTLREIKILNRFKHENIICMLDIVAADNLQELRDVYIVQALME TDMYKLLKTQRLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFG LARVADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYSKGIDVWSVGCILAEMLSNKAIFP GKHYLDQLNLILGVLGSPSPEDLNCIHNEKARGYLKSLPFKPKVPWSRFADAKALDLLDK MLTFNPNKRITVEDSLAHPYLEQYYDPADEPIAEEPFTFEMEFDDLPKERLKELIFQETL HFKPQELTPPKTTPEWIKFCEKLFGGFSLLLWIGAILCFVAYSIQASTYEDPPGDNLYLG IVLTAVVVVTGVFSYYQEAKSSKIMESFKNLVPQFALVIRNGDKLNMRAEELVVGDVVEI KFGDRVPADIRVLQAHGFKVDNSSLTGESEPQSRTPELTNDNPLETRNLAFFSTNAVEGT CTGMVVNTGDRTVMGRIANLASGLEMGDTPIAKEIAHFIHLITAVAVFLGVSFFVIAFIL GYDWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTI CSDKTGTLTQNRMTVAHLWFDNKIVEADTSEDQSYATYDRNSPTWMALARVAMLCNRAEF KTGQENVPVLKRECNGDASESALLKCVELSIGKVSEYRAKNKKVVEIPFNSTNKYQVSIH SNNQCHVLVMKGAPERILDRCSSILINGEEQELTEEWRTAFNTAYLELGGLGERVLGFCD YMLPGEEYPIGYPFNPDEENFPLTGLRFVGLMAMIDPPRAAVPDAVGKCRSAGIKVIMVT GDHPITAKAIAKGVGIISEGSETVEDIAARMGIPVSEVNPREAKACVVHGSDLRYMTPAQ IDEILSCHPEIVFARTSPQQKLIIVEGCQRQGQIVAVTGDGVNDSPALKKADIGVAMGIA GSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLIFILAD VPLPLGTITILCIDLGTDLVPAISLAYEQAESDIMKRMPRDPVNDKLVNNRLIGMAYGQI GMIQACGGFFSYFVIMAENGFWPSRLLGIRKEWDSKGINDLEDSYGQEWTYAQRKVLEFT CHTSFFVSIVVVQWADLCICKTRRNSIVHQGMLNHHLTFGLFFETALAAFLCYCPGLDKG LRMYPMRWTWWLAPMPFSLAIFVYDEVRKYILRRRPGGWVEIETYYAFKKLSKGKKIAVG VTAGAVGTCAALQDLELHPPSFPWSHSGFFQALDHSSVRRGYQVYKQVCAACHSMNYMYY RNLVGAIMTEDEAKAEAEEQLIPDGPDEEGNMFERPGKLADRFPQPYANDEAAKAANNGA LPPDLTYIVNARHGGEDYLFSLLTGYCDPPAGVTVGEEQAYNPYFPGGAIGMPQQLYNDG VEYEDGTVASVSQMAKDVATFLRWTASPEHDDRKRMGMKAIFVFLLAVSYYIKRFKWSLL KSRKLAWIRPDRSSRCTFAAGKLRDSPHFHKTRLPKVLPNILHKIGETPLVKINKIGKSA GLECDLLAKCEFFNAGGSVKDRIGLRMVEDAEKEGRLKPGDVLIEPTSGNTGIGLALAGA VKGYRTIIVMPEKMSNEKVDILRALGAEIVRTPSGASFDAPESHIGVAHRLNQEIPNSHI LDQYTNPGNPLAHYDGTAEEILDSCGGQVDMVVCGAGTGGTITGIARKLKEKCPDCKVIG VDPLGSIIAEPEDVSFYEVEGTGYDFIPTVCDRQYVDRWYKSADKPSFNMARRMIREEGL LCGGSSGSAMYIAIQAAKDYGLKAGQKCVVVCPDSVRNYMTKFLSDDWMVARSFMSDIES EEDQGPYLGEYDGERNERDERHGQGKATLPNGDTYEGMYENGKRHGHGTYRFKNRARYIG EWVKNKKHGQGTFIYPDGSKYEGSWVDDQRCGFGKYYYINGDIYEGEWQNHVRHGQGTYT YAETGTKYVGTWKDGKREGHGELVHANHKYVGVYKDDHPEGKGKYVFDIGCQQHGEYI-- -----------------------------CFLAMCGSNCVGAIVCKLDLHKKMVRRGYIA MLAVDQNYRRRGIGSHLVLKAIRAMVGDDCDEVVLETEITNRAALHLYENLGFVRDKRLF RYYLNGVDALRLKLWLKNIETLMFHIGANQKKCLKEEIHKDILVTGDYELSDAPGQKANL RVIDSKGHILYQKEDASKGKFAFTTEEYDMFEVCFESHTIAGGQTADREVYINMKHGVEA KNYQDIAKAEKLKPLEVELKKLEDLSESIVNDFAYMRAREEEMRDTNESTHSRVLYFSVF SMLCLLGLATWQVLYLRKFFKSKKLIEEMESGRTSSVGNDILGFTGNVVNKPDHGNLDWI KICEQSSKVITFIDLAGHEKYLKTTIFGMTGHAPDFCMLMVGANAGVIGMAKEHLGLALA LSVPVFVVVTKIDMCPANVLQETLKMLQRLLKSPGCRKIPVLVQSLDDVVVSATNFTSER MCPIFQVSNVSGENLDLLKMFMNLLSTRLPSSPPEFQIDDTFSVPGVGTVVSGTCLKGRI SLNDTLMLGPDPVGHFNSIVIKSIHRKRMPVKEVRGGQTASFALKKSHIRKGMVMVSPVL NPQACWEFEGEILVLHHPTTIAVRYQAMIHVGSVRQTATIITMSSEHLRTGDKAQVRFRF IKNPEYLKKDMRLVFREGRTKAVGTVTTLFPHISANTRQQRAAKKAVEXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------VKLSGMPDLTLTFINPSLFDDLSF HPCVRLKRWESERILSFVPPDGNFRLISYHIGAQNMVAIPLYVKHSISFKEGSSGRLDLT LGPKQTMGKSIENVVVEIPFPKSVLNVTLTASQGKYSFDPVNKVMTWDAGKIDPTKLPSI KGNVNVQSGSAIPDSNPTINLKFTINQMVVSGLKVNRLDMYGEKYKPFKGVKYVTKAGKF QVRT----------------------------------------------ETDNKTKWDQ LDNNTRLADRVDHIRKWKDILEKTLADLDKEIADLSASKDETERSLEAKNLPTEINLENL VTREGRQKIDLVEDEVEDQLHKEQEVIEGVKKQLQQKIDESFEQLCVLQEARQQILADLQ DKNVALGIDVDQYNLTEESPGISYKPDPLRVPKGSTTPQQWEDFSRYNKERADAEMATSR RLREAIHHTLQQTDNDLAAQDTAADYALRKRIREFEKAIDELQWQKKNTEEEIAEMEEDI RRLNDAIRAKINPTKLAQTRLENRTYRPGVELCRDNPQYGLTDEVKQLEASKRSLEEKLK QSQHALDGLEQNLHRINEDLQCKINSLKLDQQSLDARNKLERNMALTGITDLKGELATLI PKHQGTVKEFRAKHGNTKVGEVTVDMMYGGMRGIKGLVTETSVLDPDEGIRFRGYSIPEC QEVLPRAPGGEEPLPEGLFWLLLTGEVPSEAQVKSVSKEWANRADLPSHVVTMLNNFPSN MHPMSQFSAAIIACNTESKFKKAYEMGVKKTEYWEHVYEDSMDLIAKLPTIAATIYRNLY RDGTSVGAIDPDKDWSANFTSMLGYEDPMFTELMRMYLTIHSDHEGGNVSAHTCHLVGSA LSDPYLSFAGGMTGLAGPLHGLANQEVLVWLTKVNWTEESLKEFVWETLKT-SVVPGYGH AVLRKTDPRYQCQREFALKHLPNDPMFHLVSDLYKIVPDILLEQGKAKNPWPNVDAHSGV LLQYYGMTEMNYYTVLFGVSRALGCLSSLVWDRALGLPIERPKSMSTEGLMKLCEMPFVA PKTEKCEICSKSVYAQERQEAGNKIYHKLCFKCNHCKMSLNLNNYKQADGLLYCNKHFAE LVTAKNTQ---MFVHRDTPENNPDTPFEFTAENIKRCDEIIKNYPVGHEAAAVMPILDIA QRQHGWLPISAMHSVADMLKMPRMRVYEVATFYTMYNREPVGKYFVQICTTTPCMLGGVG SDIIL---------------------LAEVECLGACVNAPMFQINDMYYEDLTVNDTNEI LNDLKAGKTPKPGPRSGQSGRFASEPKGGLTSLSGPPPGPGFGVRADLMQKYEKLEKIGE GTYGTVFKAKNRETQEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLYDVLHS EKKLTLVFEYCDQDLKKYFDSCNGEIDQDVVQSFMYQLLRGLAFCHSHNVLHRDLKPQNL LINKTGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIF AELANAGRPLYPGNDVDDQLKRIFKLLGTPTEETWPGMTQLPEFKPYPIYVNQQQVVPKL NAKGRDLLLALLHCNPSKRLSAEEGMQHSYFMDLNPAVKXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXX--------------------------------------- ------------------------------------------------------------ -----------------------------DMVADFQSRSDIFVFLLSTRAGGLGINLTAA DTVIFYDSDWNPTVDQQAMDRAHRLGQTKQVTVYRLICKGTIEERIIQRAQEKSEIQKMV IQGGDVRPDVLRPKEVVSLLLDDDDM---MSLETVPKDTRHLRACLLCSLVKTLEQFEYD GCDNCEEYLQMKNNRDAVYECTSSSFDGMVAMMSPEDSWVGKWQRINRFKKGCYAVSVTG SLPPGIISELKSKGVVYRSRDTSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXYIQSLPKEVKRRIKALKKLQFAMIEIESKFYEEVHELECKYA AKYAPLCDKRTDVVNGGVEPTDSDCDWPSDDEDEDEKAKIKESEPVSGVPEFWLTIFKNV DLLSDMIQDHDEPILKHLIDLKVKFMMGFKLEFVFEPNEYFSNTVLTKEYIMRSEPDSED PLSFEGPEIIKCKGCTIDWQKGKNVTVKVIKKVQKHKGRGTKRTVTRTVQNDSFFNFFTP PDVPEGMADEDTDALLAADFEIGHFIRERLVPRAVLYFTGEALEDEDEGEEEEGDVILLK EGTDSSQGKPQLISNINACGAIVDAVRTTLGPRGMDKLIVNGQGKATISNDGATIMKLLD IVHPAAKTLVDIAKSQDAEVGDGTTSVVLLAGEFLKQSKSFIEEGVHPQVIVRAFRKASY LSVQKIKEIAVSVKKDAKQERELLLKCAATALSSKLVARQKDFFADMVVDAVNSLDDLLP LEMIGMKKVQGGGLEDSMLVDGVAFKKTFSYAGFEMQPKKYEEPKIALLNIELELKSEKD NAEVRVDNVEEYQAVVDAEWTILYDKLDKIHQSGAKVVLSKLPIGDVATQYFADRDMFCA GRVPEDDLKRTMKACGGSVQTTVSNLTLGTCKIFDERQIGGDRYNFFMGCPKARTCTIIM RGGAEQFIEETERSLHDAIMIVRRAKKNDSVVAGGGAIEMELSKFLRDHSRTIAGKEQLL IGAMAKALEVIPRQLCDNAGFDATNILNKLRQKHAGRWFGVDIRAEDIADNFEACVWEPS VVKINALTAASEAACLILSVDETIKNPKADQGGGGRGRGRGRPMKGNNVIPNAHFHKDWQ RRVRTWFNQPARKQRRRDRRVKKAKEIAPRPIGGPVRPIVRCPTFKYNTRVRAGRGFTIE ELKNAGINKRQASTIGIAVDYRRRNKSVESLQQNVQRLKEYKSKLILFPKKQSKPKKGDA TEEEMKMATQLTGPIMPFPHIHKNEKARKITKEENKHSVFNAMRKQRANARLVGMRAKKA REAMPNIKVFSGTSHPDLAQKIVDRLGIELGKVVTKKFSNQETCVEIQESVRGEDVYIVQ SGCGEINDGLMELLIMINACKIASACRVTAVLPCFPYARQDKKDKSPISAKLVANMLSVA GADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENIPEWRNSIIVSPDAGGAKRVT SIADKLNVDFALIHKERRKANEVASMVLVGDVKAKVAILVDDMADTCGTVVHAAEKLIEA GAKSVYAITTHGIFSGPAVSRINNSNFECVVATNTIPQDQNMKNSTKIQ----------- -------------------LSCRFYEHRYPEQEDVVMVNVRSIADMGAYVHLLEYNNIEG MILLSELSRRRIRSIIKLIRVGRNECVVVIRVDKDKGYIDLSKRRVSPEDVVKCEEKFAK AKCVNSILRHVGELLEYSNDEQLEELYRKTAWFFDKKYGKPGSSYEAFKHAVTNPEILDE LEIDDNTKKVLAENIKRRLTPQAVKIRADIEVACYDYEGIDAVKNSLRAGLNLSTEDMPI KINLIAPPLYVMTTQTLERSQGMARGQQKIQSQQKNAAKQQAQKKDVKKAAAAALQFSCA VCKSQMPDPKTYKQHFENKHPKAPLPADLQNV---------------------------- ------------------------------------------------------------ --------------------------------------------------KCGGCLRPIM DNYISALSKQWHPECFVCRECHMPFGSTSFYDHDGFPYCETHYHAKRGSLCANCSKPITG RCITAMYKKFHPEHFVCAFCLQQLNKGTFKEQNDKPYCHPCFVKLF-------------- --------------DRPDGTYCFRLHRERIYYCSEVLMKKAGNIANDNLMSFGTCFGKFT KTRKFRLHITALDYLAPYAKYKVWVKPSAEQQFLYGHHVMKSGLGRITENTPQYQGVVVY SMSDLPLGFGATAKTTQECRHTDPMTIVCFHQADIGEYIRSEDTLADQRKLFVGGNWKMN GNKASIDGIIKFLNEGNPATDVVVAPSPIYMEYVRSRLIGVAAQNCYKAEKGAFTGEISP QMIKDNGCEWAILGHSERRNVFGETDQLIGEKVAFCLQSGLHIIPCIGEKLEEREAGQTM TVCFRQLKASDWSRVVIAYEPVWAIGTGKTASPQQAQEVHAALRKWLGENVSPDVAKTTR ILYGGSVSAANCKELATMGDIDGFLVGGASLKPDFIQIINAREREGLLDPAWEKQQKKTF TAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGEQLSKPDKGKMRFHKIANVNKAL QFIQSKGVKLVSIGAEEIVDGNLKMTLGMIWTIIVQNFHMSWKDG--------------- ------XDNPLENLNLAFDIAEKHLDIPRMLDAEDMVNSVKPDERSVMAYVSSYYHAFSG AQQAETAANRICKVLKVNQENERLMEEYERMASDLLEWIRRTTPWLENRTTDNTLPGTQR KLEEFRDYRSQHKPPKLSEKAKLETTFNTLQTRLRLSNRPAYLPTEGKMVSDIANAWKGL ETAEKGFEEWLLSELQRLERLDHLAKKFKHKCDIHEEWSYGKEDMLQAQDFKQCRLNELK ALKKKHEAFESDLAAHQDRVEQIAAIAHELNTLGYHDAPAVNARCQRICDQWDLLGTLTQ QRKNALEEAERILERIDQLHLEFAKRAAPFNNWMDGAKEDLVDMFIVHTTEEIQGLIDAH EQFKGTLGEADKEFNAIVALAQEVKRIAQQFGITSAGDNPYSTLTAQDIANKWSEVRQLV PERDTVLQTEMIRQQNNERLRRQFAAKANMVGQWIERHLDAVASVGVQKGSLEDHLNKLR GIEKEVFAFKPNMDELERYNQDVQEAMIFENRHTQYTMETLRVGWEQLLTTVARSVNEVE NQILTRDSKGISNEQMDEFRKSFNHFDKKRNRRLEPKEFKACLVSLGYNIRDDRQGEADF QRIMSTVDPNGAGYVTFDAFLDFMTRETTDTDTAEQVMQSFRILAGDKPFITADILRREL PPDQAEYCIQRMAPYVGHDAAPGALDYSSFSTALYGESDLNKLSIDSVDLKDKRVIMRVD FNVPLKEGVITNNQRIVAALPTIKYALEKGARSVVLMSHLGRPDGKRNEKFSLKPVAEEL KKLLVRDISFLADCVGPDVEAACASPAPGSVILLENLRFHIEEEGKGTDADGKKIKADPA KVEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGCQLAQRASGFLLKKELAYFAKALEKPE RPFLAILGGAKVADKIQLINNLLDKVNEMIIGGGMAFTFLKVLNNMEIGNSLYDEEGSKI VQSLIDKAKSKNVQILLPTDFVTGDKFAEDAAVGVATVSTGIPAGSMGLDIGPETNKAVA AVIARAKTIVWNGPPGVFEFAHFAAGTKSMMDAVVAATQSGATSIIGGGDTATCCAKFGT EDKVSHVSTGGGASLELLEGKNLPGVAALSEA---------------------------- ------------------------------------------------------------ --KHTGAGILSMANSGPNTNGSQFFITLAQTQWLDGKHSIFGRICAGMTVVNRIGMVETD NNDRPVDDIKIVRRRSREKDKSRSRSRERKKKPNKYWDIPPPGFEHITPMQYKAMQAAIP FAGSAISRQARRLYVGNIPFGVTEEMMMEFFNSQMRMTSLSQAEGNPVIACQVNLDKNFA FVEFRSVDETTQAMAFDGINFQGQSLKIRRPRDYQPLPGMAETPSVGVVSTVVQDSPHKI FIGGLPNYLNEDQIRELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDQACAGLNGMQLG DKKLIVQRASVGAKNAQQAPVQLQIPGLNVSDVPTEVLCLMNMITPDELEDEDEYEDILE DVKEECSKYGIVKSIEIPRGIKGVEVPGVGKIFVEFNSVIDCRKAQQALTGRKFANRVVV TSFFDPDKYHRREFFIPMFDRVLVERMAAETKTKGGVLIPEKSQAKVQSATVVAVGPGSR TDAGSVVPPSVKPGDQVLLPEFGGTKVQLEEKDY-------------RLKGQIPDIKTSL NIVKHMQGKKESLHTQFQMADNLYVKAKIPPTEKVNLWLGANVMLEYTLDDAQALLQKNA AEKSLETVDNDLSFLRDQTTTIEVNMARVYNWDVKRRQAGKS---DALARAGLHFDELNK IRVLEPEISSQTGELKEECKEFLDKMTEFQKIVGSFITVVDEVGSEVEKEKMKAIGSRNL LKSIAKQREAQQQQLQALIGEKSMQLERLRIQYDSLQKEEKEQNDFIEQ-----RDRSRE RDRSNERRRRSKSKDKENLTLEERDARTVFCMQLAARLRPRDLEQFFSSVGKVRDVRIIT DNKTRRSKGIAYIEFADSDSVPLALGLNGQRLLGVPIIVQPSQAEKNRMAGKTGPMRLYV GSLHFNITEDMLRGIFEPFGKIDHINLVMDNETGRSKGFGFITFHNAEDAKKALEQLNGF ELAGRPMKVGHVTERQGASSVFDTDDMDRAGIDLGATGRLQLMAKLAEGTGFQIPTAAAN ALSLQPEVAAPPIATQCFMVSNMFEPQNSNPNWEMEIRD--------------------S PQGNVYVKCPTIAAAVASVNSIHGRFFAGRVITAAYVPLPNYHQLFPDALRASQLIMPSN ----------------------------------------------------------NV LFSHLDDNERSDIFDAMFPVHRHAGEVIIQQGDEGDNFYVMDSGEVDVYVHNDWVSTIGE AGSFGELALIYGTPRAATIKAKTDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLTKVSIL DSLDKWERLTIADSLEPVQFEDGQEIVRQGEPGDDFFIIIEGQASVLQRRAENEESVEVG KLGLSDYFGEIALILDRPRAATVVARGQLKCVKLDRARFE-------------------- -----AQYQGTAQLSRLLYISDHALSYLMSTYNTNMYQAVHKKLQDAITGNAPALDTVWI ETHSKKAALKLEKLDTDLKNYKSNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDY CTSAKHVINMCLNVIKVSVYLQNWSHVSSYVNKAEATPQPSEGTSSSQAVATKLKCAAGL AELATKKYKTAARYFLQANFDHCDFPELLSPNNVATYGALCALASFDRQELQKNVISSSS FKQFLELEPQLRDILHQFYDSKYASCLKLLDDIKDNLLLDMYLAPHVVTLYTEIRNRALC QYFSPYLSADMTKMATAFNRSVGALEDELMQLILDGRISARIDSHNKILYAKDTDQRSST FERSLTMGKEYQRRTTALILRSAMLKNNIHVKSPPREDGQGGEMALAPGN---MSERSAF LSKAEEIADQVLRHGKHILPHVARFCIVSTFLEDGIRMWTQWQEQRDYINATWSCGFFLA SMFVIVNLLGQLGGCSMVLIRKYVNAACGLLFFIIALQTVAYSILWDLKFLMRNLALCGG VILLLAESKAEGKSLFAGLPSLGENTGRTYMQLSGRLLLVLMFLTLLRFDFSFFHLVQNL GGTALILLIAVGYKTKLASLVLVVWLTILNFYFNAWWSVPDYKPMRDFLKYDFFQTLSVV GGLLLVVALGPGGYSMDEHKKKW---VTLIPGDGVGPEVMGSVKDVFSAAGVPVDFEELF ISKNRVCLKGIIATPLQTLNMQFRQKLDLFANVVRVRSLPGYQTRHNNLDFVIIREQTEG EYSALEHESVKGVVESLKIITRANSKRIAKFAFDYATKHGRKKVTAVHKANIMKLADGMF LKSCEEVAELYPKIEFEPMIVDNCCMQLVSNPYQFDVMVMPNLYGNIVDNLASGLVGGAG VVPGECFSPEVAVFEQGARHAFASHAGRNMANPTANLLAAANMLRHIHLERY-------- -------------------------------TEDFQKFFDKAARTVERALYEKVDIFTDY AGADEDDGLQEGEKLQLSRSFFDERWSKHRTVTCMDWSSQYPELLVASYNNNEESPHEPD GVALIWNVKYKKTTPEYIFHCQSAVMSCCFAKFHPNLIIGGTYSGQIVLWDNRSNKRTPV QRTPLSAAAHTHPVYCVNVVGTQNAHNLISVSTDGKMCSWSLDMLSQPQDSIELQNKQAK VAVTSFSFLSGDVNNFVVGSEEGAVYTACRHGSKAGINDTFEGHMGPVTGIDCNSVPGAV DFSQYYITSSFDWTVKLWNIKENRALHSFEDNSEYVYDAKWSPIHPSLFATVDGSGRLDM WNLNNDTEVPSASTINVALNKCLWHSSGHNIAVGDDLGKISLYDVGEAVAVPRNDEWQRF VHTIQDLKTEQADQDDE------------------------------------------- ------------------------------------------------------------ ---------------CKFLVDRLKIKTLPTICLVRDTKTVDYIVGFSDLGNRDDFTTEVL EWRIATADCINYSGDLMTPPTQGQKAKTIRGKDDDDKTLVLTAFGSSDKLKVEYQPEPGP GEVLVKVMAAGINFAELMAQQGLYDPKMKTPIVLGFEGSGEIIKVGED-TDFKVGQGVIC VIGLWREYAVHIFPKPEGLTYPQAAAIPVNYITAYHMLFDIANLRPNRSVLVHMVAGGVG NAAVQLCRSVPNVTIFGTCSAKHNVMREAGVQHLIDYKTEDYVTEIRKISPKGVDIVLDP LSGADSKKGYNLLKPLGTIVHFGAANMVTGQTRDLLKAAWTYCCTKSYSPFGMMEKNRCV AGYHLGKLVAFQGLSELHKDGFVNPVVDSVWPLEDAGQAMSRLIERKNVGKVIFCPQK-M SRKTPSDFLKQISGQPVVVKLNSGIDYRGVLACLDGYMNISLEHTEEYVNGQLKNKYGDV FIRGNNVLYISTQKRRLMTNDQGSLLLKKQLNELSRHPVEGFSAGLYDDDNIYKWEVMII GPPDTFYEGGFFKAELTFPKEYPQKPPKLKFITEIWHPNIDKTGDVCISILHEPGEDKWG YEQPEERWLPIHTVETIMVSVISMLADPNDESPANLDAAKDWREDREAFKKKVSRLVRKS QD-TVRPVNALMQKTLSDFGRYVGECMPKFVQKVEVTTGDELDIMIHPDGLIPVMTFLKD HTNAQFENIVDIAGVDVPTRQHRFEIVYMLMSLRYNARIKVKTYTDELTPIATVNNVYAG ANWYEREIWDMFGVYFSGHPDLRRILTDYGFEGHPFRKDFPMSGYVEVRYDDEVKRVVAE PIELAQEFRKFEYNTPWEMFPSFREN---------------------------------- -------IPQFSTIEYTITRATCHPPVFLIVLDTCMDEEDLTAVKESLQMSLSLLPPNAL IGLITYGKMVQVHELGCEGCSKSYVFRGTKDLNAKQIQEMLGIGRGNTQLPANRFLQPLH KCDMAVTDLLNELQRDPWPVAQGKRPLRSTGAALSIAVGLLECTYPNTGARIMLFAGGAC TQGPGMVVGDELKYPIRSHHDLEKDNAKYMKKAMKHYEALANRSANNGHIIDIYACALDQ TGLHEMKFICNSTGGHMVMGDSYNTSLFKQSFQRVFSKDVKNEFKMAFGLNMEVKTSREL KVQGCIGACIGLSTGPSVSDNEVGIGGTQTWRMCGAYPNTTYAFVFEVVNQHNAPIPQGG RGYIQFITQYQHSSGEKRVRVTTIARNWADASINIPHIAAGFDQEAAAVVMARLAIFRAE TDDGPDVLRWLDRMLIRLCQKFGDYHKDDPNSFRFSEQFSLYPQFMFHLRRSQFLQVFNN SPDETSYYRHCLLVEDLTQSLIMIQPILYAYSFDGPPEPVLLDTSSIMPTRILLLDTFFH ILIYHGETIHEWRKAGYKDLPEYENFKQLLLAPVDDAQEILQTRFPMPRYIDTEAGGSQA RFLLSKVNPSQTHNNMYAD-GGHVLTDDVSLQVFMDHLKKLAVSSSSMSSLSHEEQLKLI SDLEIEMMADMYNRMSNACQKKCVPPKYKDAELSKGEAVCLDRCVAKYMDIHDRIGKKLT NMSVKDEETMKKIQ-ASNPSVIHKVIMVGSGGVGKSALTLQYMYDEFIEDYEPTKADSYR KKVLLDGEEVQIDILDDYAAIRDNYFRSGEGFLCVFSIIEQESFSATQDFREQILRVKND ENIPFLLVGNKADLEGSRQVSVEEAQQRAQQWNVPYVETSAKTRANVDK----------- ---------------KLYTGLRDVVTEHLVNKVRSDVVIALNNNFLQTLNSAWGDHQTSM VMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVIRWPQIRSHLRETLLDMIAKERRGE VTDRLAVRNSCQMLMILGIESRHVYEEDFEQPFLEKSREFYKMESQKFLGENSASVYINK VEQRIREEAERAKHYLDVSTEERIVKVLEDELISKHMKTVVDMENSGVVHMLKNNKTEDL ACMYKLFSRVAEGIKTMCQCISGYLREQGKALVTEDGETKNAITFVQSLLDLKDRFDHFL HESFANDKVFKQMISSDFEHFINLNGKSPEYLSLFIDDKLKKGVKGMTEQEIENVLDKTM VLFRFLQEKDVFERYYKQHLAKRLLLNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFKD MTVSNT------------------------------------------------------ ----------------------------------------------------------NS KERRTYEEIKAESDIPEKDLIRALQSLALGKVSQRVLTKEPKTKEIENSHIFSVNDGFTS KLHRVKIQTVAAKGESEPERKETRNKVDEDRKHEIEAAIVRVMKARKRMLHNVLVAEVTE QLKSRFLPSPVVIKKRIEGLIEREYLARTPEDRKLYTYVADRLNVFPSRMALTNMKARLK GAQKGHSLLKKKSDALTMRFRQILRKIVETKTLMGDVMKDASFSLAEAKFAMGDFNHLVL QNVNKAQIKVRSKKDNVAGVTLPIFEEYADGSDCYELTGLSRGGQQIDRLKKNFAKAVEL LVELASLQTAFVTLDEVIKITNRRVNAIEHVIIPRIERTVAYITSELDEGEREEFFRLKK IQKKKGNDLGSNLLEEYDEDLLFPLRVLVTGAAGQIAYSLLYSVAKGDVFGKDQPISLVL LDIDAMMTVLNGVVMELRDCALPLLADILPTSDVEAAFKDVDVAILVGAMPRRAGMERKD LLKANVKIFKQQGQALDKFAKKNCKVVVVGNPANTNAFICKKYAPTIDSANFTCLTRLDQ NRACSQIAMRQNVSNVIIWGNHSSTQFPDVSNAVVVVEAVKDDAWLKGEFITTVQKRGAA VIEARKLSSAMSAAKAICDHLRDWWAGIPEGQWVSMGVESDGYGITPGLIYSFPVKTDHT YTIVKDLENDTFARERMDATMKELLEERDEALAAC------------------------- -----------------------------------KQLGQAEGVPQVYYFGPCGKYNALV LELLGPSLEDLFDLCDRKFTLKTVLMIAIQLITRMEYVHSKHLIYRDVKPENFLIGRQSN KKQHLINIIDFGLAKEYIDPETHRHIPYREHKSLTG-ARYMSINTHLGKEQSRRDDLEAL GHMFMYFLRGSLPWQGLRADTLKERYQKIGDTKRAAPIEVLCENYP-EFATYLRYVRRLD FFETPDYDHLK--------------------------------VMSSTNGELGPTAGHSN TPITAPTEVEVVDETKCCXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXERQLDCALDLMRRLPPQQIEKNLSDLIDLTPELCEDLLSSVDQPLKIARD KAVGKDYLLCDYNRDGDSYRSPWSNQYEPPLEDGAMPSERLRKLEEDANGAFEMYREMYF EGGVSSVYLWDLEHGFAGVILIKKAGDNSKKIRGCWDSIHVVEVQEKSSGRSAHYKLTST VMLWLQTNKAGSGIMNLGGSLTRQVENDCTVSDNSPHIANIGKMVEDMENKIRNTLNEIY FGKTRDIVNGLRSVIPQQREGLKIELAEALKKKGQXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXKSPTLKDRIMAPAGDGAFTMGKGILAGASAIGLG ALCFYGLGLSNEVGAVDRAALWPDIVRDRVKTTYAYFGGSLAITAMARSPAVMRIVAGGG LMSLFGTLAAMIGTGMLVRSLPYEEGSKQMAWMLHSAVIGTIIAPLTFLGGALMLRAACY TAGVVGGLSTLAVCAPSEKFLNMGGPLAMGLGLVFVSSIGTWFLPPTTALGAGMYSVAMY GGLVLFGMFLLYDTQKIIKRAETHPIYAAQPYDPINNSVGIYLDTINIFIRIAMILAGGG SRRK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------LQRNPFFPKNFLSVGDWTARIWSEDIRESSIMWTKYHMSYLTDGAWSPV RPSVFFTTRRDGVLDIWDFIFKQNDPTLSIQVCDXCL---RVQDQGRLIATGSLSGTTTL LELSDYLYTMQRNEKSLVTAMFERETRREKILEARHREMKLKER----WNELVEKVSPIA NPLASRKLAKKIYKVIKKAMRKGVREVQKYVRKGEKGLLFFAGDTNPIEVICHMPAVCEG KEIPYCYTPSKDDLGEACGSKRATCMVMVKQHDDYSDLYDELQKELKSLPMP-MPQETWE EEGLENNPKLDLAQWMFMLKLDTHKNDEKIKKDVLEVIKSEDMAPFYEEVCAELGWKVDQ PLLDKMKAANEAKYKEIDLKIEDAEKNLGETEVRDFMLKKAEYMSRIGAKDLCLTQFRKT AEKTVTLGYKMDMIFHQIRIGLFYMDHDLVKRNLEKAHSLIEEGGDWDRRNRLKVYKGLY SMAIRDFKTAANLFLDTVATFTSYELMDYKTFVRYTVYCCVIALERPKLREKVIRGSEIL EVLHSLPDVKTFLFSIYNCHYKDFFSTLATVEDYMKGDRYLEPHYRYYMREMRILAYSQL LESYRSLTIEYMATSFGVTQDFIDRELSRFIAAGRLHCKIDKVGGIVETNRPDSKNWQYQ ETIKKGDILLNRVQKLSRVINISRGLKHSAKKFVGIPYNKLTIGVPKETFLNERRVACVP QTVATLKKGFNVQIEAGAGVEAKFNNSDYEGAGAAIDKNKIFSSDIVLKVRPPSLEEAAM FSGGNTLFSMIYPATNKDIVDALAQKKMTVYGMECVPRISRAQTYDVLSSMANVSGYKAV IEAANNFGRLITGQITAAGKVPPAKVLIIGGGVAGLAAAGTAKNMGAIVRLFDVRAAVRE QAQSMGAEFLTINLEESGEGAGGYAKEMSPEFIKAEMDLFAKQCKECDIVISTALIPGKK APILITKEMVESMKPGSVVVDLAAEAGGNIETTKPGELYKYHDVTHVGYTDFPSRLPTQS STLYSNNISKMLLSFSYIVNLEDEVCRGSMILQEGKMMWPPPAQKPHNYFQESLKDSFMY AAGLSGALSLGAISPSPQFANMVTTFSLAGIVGYHTVWGVTPSLHSPLMSVTNAISGITA AGGLILMGGGYTPENSVQTLAAVAAFISSINIGGGFVITQRMLDMFKRPDDPPEYNYLYG IPAAAFLGGYGYLAMGEYPDVHNLAYLAASLCCVGALTGLSSQKTCRLGNALGMIGVSSG IVATLGIIQPNQEVFTQMATCMGAGGLIGAMAAKRMEVTDLPQMVALFHSLVGAAAVITC VANYMHEFPQFDTDPAAGVTKAVAYLGTFIGGVTFTGSLIAFGKLQGTLKSDPLHLPGRH AMNLGMFLSCVGGMGYFLYDPTITGMSMLGMCTGLSSVLGLTLTAAIGGADMPVVITVLN SYSGWALCAEGFMMNNNLMTIVGALIGSSGAILSYIMCKAMNRSLPNVILGGYGTTSTGT GEAMKITGTHTEINIDETVERLLEAENIMIVPGYGLCVAKAQYPIAELVKLLSEKGKHIR FGIHPVAGRMPGQLNVLLAEAGVPYDQVFEMDEINDDLPEVDITLVIGANDTVNSAAEED PNSIIAGMPVIRVWLGKEVVVMKRTLGVGYAAVDNPIFYKNNTSMLLGDAKKTCDALLAR TRMPPPATIPGCPPGLEYLTQIDQVLIKQVVELLEVFLGWESNNRYKVLNTLGQQIYFIQ EETDCMQRQCCGPSRGFILHVTDNNNQEVMRIVRDFKCCAGCCWCANCSLELQVEAPVGQ VLGYVKQEGWKPKLGIYDAVGLLGGPCCVCNAPCC-GDVEFPVTDHEIGMCAKHWTGALR EYFTDADNFHIKFPMDMDVRMKALMFGTMMMIDFMYFEQKKNKADPELQQFIAMETQKAQ FQSQVHRLTDTCWDMCVDKPRDKFDYKTETCMSNCVGRFIDTSLHITGRFQQLLQKSM-- ----------------DHDSKETRLTLMEEVLLLGLKDREGYTSFWNDCISSGLRGCILV ELGLRGRVELEKTGMRRRSLLNRKIICKNDAPTGDVLLDEALKHIKETQPADTVQSWIEY LSGETWNPLKLKYQLRNVRERLAKNLVEKGVCTTEKQNFLLFDMTTHPLVESTIKQKLVK RVQESVLARWLNDPQRMDKRSLALLYLAHSSDVLENAFAPLSDDDYEVAMRRVRDLLDLD FEAESCKDGANELMWAVISAFSKAKKLAQVNEENCEVCVKFMTRFINELDDIEDAFRKKC KTSRKDDNRFCYYVGGLEESATGIVGEMSKPVSWGMPADKVCMKLYRKDQQICDLKYDKV LDLTKVDLKKLKVKDLKSILSDWNEQCKGCTEKTEYIKLVEELMPKYAPEAH-------- ----------------------------------------CRAVARELNFSSAEQMEKFR LEQKVLFKGKCLEEWYFEFGFVIPDSTNTWQSIIEAAPESQMMPASVLNGNVIIETHFFN GDLLVSTSKVRVFYVMPKVVSRSVVCTDTNDQEEYKGEKPLYVYYCLCGQMSLILDCPVD KLPFRKRDSARVIDSAKHAHKITADPDETTYLKRKEGIEKQYRLKCKKCGLLLYYRHQNI VTFIVDGALITGADDKKDIYRQIAEPKPVMVKKHTKN----------------------- ---------------------------------------------LARNCAKVATQNQSR GYADMAFTFASPSQVNVKQVDVPSFSGSFGILPDHVPLLAVLQPGVVTVMEGEGASKKYF VSSGSITINDDSSVQILAEEAAPLESLDINAIREGVQKSSQELSTEQAKAEAQIALDTYE AMQKAIECKFFVTEFQKRLDESSKSKEVLETGHGLEKKKRFKYVTSELRLTEALHEPHIC EKILEYNVHAERKGSLRYAKGMSETFQTLHGLVDKGVKVELGIPYDLWDKPSAEVTKMHR KCFQMAEYHEDDIEEWYYNLQENLLQYLCAERYL-----LFSPTDVTSEGDVQSAVLALE KFGSLNVAVNCAGIGVAKVTYNKSKDTVHSLSEFQKVLTTNTVGSFNVIRLAAQAMNKNE PNEDGQRGVIVNTASVAAFDGQRGQAAYSASKGAIVGMTLPIARDLMNMGVRVNTVAPGL FDTPLLASLPEKVRTYLASTVPFPQRLGLPDEIAHTIQFLVENPMMNGEVIRVDGAIR-- ------------------------------------------------------------ -----------------------------------------------------------E NYGMPFSRLENGKIYQRAFGGQSLDFGKGGQAHRACCVADRTGHSMLHTLYGRSLYYDTD YFIEYFAMDLIMENGECKGVIAMSMEDGNIHRFRANNTVLATGGYGRSYFSCTGAHTCTG DGTAMVSRAGLANEDMEFVQFHPTGIYGAGCLITEGCRGEGGYLINSEGERFMERYAPTA KDLASRDVVSRAETIEIREGRGVGKDKDHCYLQLSHLPPEQLNTRLPGISETAMIFAGVD VTRDPVPVLPTVHYNMGGVPTNYRGQVIQSNKDDIVVPGLWAAGEAACVSVHGANRLGAN SLLDLVVFGRACANSIAEVNKPGDKLPDISQNAGEESVANLDRIRFADGDTRTADMRLSM QKAMQTHAAVFRDGPTLDEGCRKLDALWKDLNLKVSDRGMIWNSDLVETLEYQNLLLNSL QTAHSAANRKESRGAHSREDFPDRIDEFDYSKPLEGQTEKTYDEHWRKHSMSYVD-NNGK VRIDYRPVTDSVLDASKIETIPPKIRAY-----QEDIISNTKTVVQGLDTLKVEHHQILN SLLSSMKTIKEGDTNLVEEKANLLKKSLEMIDLGIGEAQVMMALANHLQ--XAEKQKLRA QVRRLCQENAWLRDELANTQQKLQQSEQKVATLEEEKKHLEFMNEMKKFDAEDDLGFPDD DEESQGSAMAQAASGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHD HPDVATMLNILALVYRDQGKYKDAGTLLHDALSIRETTLGRDNPAVAATLNN-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------FKQMENIQTFVNFCEKYGMDKQGTFQTVDL FEGRNMPQVMNCIQQLGTECQRHGFSGPVIGPKPVEKNVREFTEDQLKAGQLQAGTNKCA SQSMGGVRHVADIKADDMDKRGQNVIGLQAGNKGASQSGI-MGGVRHVADIRADDMDKSG QSVIGLQMGSNKGASQSGMSMGGVRHVADIRADDMDKVGQGVIGLQMGSNKGASQSGMSM GATRHVSDIKVDSPA--------------------------------------DSSTIGL QMGSNKGASQSGMSMGGVRHVADIRADNMSGQGVVNLQYGSNQGASQQGMSMGGRRN-MP ETFSFGVDPISCHAWNADKTQLALLNNHQVHIYQFQWEKTDTLDEHVQRVTGIDWATQTN TIVTCGADRNAYVWPTLVILRINRAATCVKWSPQENKFAVGSGARTISVCYFEKENDWWV SKHIKRPIRSTITCLDWHPNNILVAAGSTDFKARVFSAYIKEVEPKPEGTNWGKKMTFGN LMAEFADVCGWIHSVSFSASGEKLAWVGHDASIYVVTAKCKTDYLPFTSCLWVSESNLLV AGHDCCPIVFSHNGGSVQFMAKVDAAKFSAMKHFQDRDKKATALNTIHQNTITQVSIYQG DKATCSRFTSSGADGKLINWD--KESDGYVGFANLPNQVYRKSVKKGFEFTLMVVGESGL GKSTLINSMFLTDLYGNDYPGPSHRIKKTVEVERTQVLLKEGGVELKLTVVDTPGFGDAV DNSNCWQPVIENIEKKYDEYLNAESRVIRNIKPDSRVHCCLYFIAPNGHGLKPLDVEFMK RLHDKVNIIPLIAKADTMTPDECREFKKTVLNEIAQHKIHIYEFEDDDDAKIQKRLKERV PFAVVGSNTVVDSNGRKVRGRIYPWGIVEVENLDHNDFIALRNMLIRTHMQDLKDVTNNV HYENFRYNKLAAVTKNPLLQMEEEKTEHVNKMKKMEAEMEQVFEMKVKEKMQKLKDSEAD LERRAEQMKKSLEQQSKELDDKRAQFEKEKSVFEAQEEMARRYDSRTTIFSPEGRLYQVE YAMEAIGHAGSCLGILAKDGVLLAAEKRNTNKLLDEVSYSEKIYKLHDDMAISVAGITSD ANVLTNELRLIAQRYILQYQEPIPCEQVVSTLCDVKQAYTQFGGKRPFGVSILYMGWDRH YGFQLYQSDPSGNYSGWKATCIGNNSAAAVSMLKQEYKE-EVDLKTAVELAVKVLSKTMD TNKLTSDKVEVATLIREDGKTRTRIMPGKELDVYIQKYQEEEARIEAEKKKQLIEAWERL KLLSRKRQERLFGAHEMQRFNRDADETMAWIAEKDTMLSTDDYGRDLASVQTLQRKHEGI ERDLAALGDKVKNLAGESERLAQTHDN--EEIHRKQSDIESQWARLREKAANRRARLDDS YNLHRFLSDYRDLISWITDTKSVINADELAKDVAGAEALLERHQEHKGEIDAREDSFRST AESGRKLLESDHYAVEDVKERLVTLANEKTSLLELWEERRILYEQCMDLQLFYRDTEQAD AWMSKQEAFLANEDLGDSLDSVEALIKKHEDFEKSLAAQEEKIKALDEFASKLIENEHYA ADDVATRRDALLQRRNALYERSSIRRHRLEESYKWQLFERDCDETKIWINEKLKAASDEG YLDPTNLQGKVQKHQNFEAEVNANQARIETVQKTGAELIEANHYNKDHVQDRLNDLESLW KQLVDQTTRKGAKLKDASDQQSFNRNVEDVEVWLAEIEGQLMSEDYGKDLTSVQNLQKKH SLLESDVSSRQDRIDSIFQSAEAFQNAGHFDSENIVAKKAVVVERYNNLLAPIGNRKTKL TDAQRLQQFVRDVEDEEDWIREKEPIASSTNRGRDLIGVQNLMKKHQALSAEIAGHEPRI DSVKSVGNAMMEEGHFAADDIKEKINELDDKWKALKDKSNQRKVDLEDSLQAQQYFADAN EAESWMREKEPIVGNTDYGKDEDSAEALLKKHEATMSDVEQYKVNIDSLKDQAAACKQQE APVVDDIGKECVVALYDYQEKNPREVSMKKGDVLTLLN---------------XXXPAAY VKKIDSSLTASQSQLADEYTISVRQQQIENQYDNLLDLGNQRRVKLEESCKAYQLVREAG ELAQWIQSKETVALSAEVGDDLEQVEVIQRKFDDFQKDLKANEARLVELNTIAERLTAMG QTEAAEKIRIQIEDLNQRWAGLQQVTQERAQTLGSAHEVQRYHGDADETKDWMDEKEATL QSDDFGHDLATVQRLQRKHEGLERDLAALGEKVKELDETANRLMQTHPDQAQSIYEHQKE INDRWNMLTQKADDRKAKLLDSYDLQRFLSDYRDLTSWINSMMALVSSDELAKDVTGAEA LLERHQEHRMEIDARGGTFQTFEMFGNQLLQNNHYASDEVRNKLNELAKARQDLEQGWID RRAKLDQCLELQLFNRDCEQAENWMAAREASLKDEVDGSEGVESLLKKHEDFDRAINSQE EKINAIVSFADQLQANDHYDTPGIENKKTQVLDRWANLKSALLDNRAKLGEAQSLQQFSR DVDEMEIWITERLQMALDESYKDPANIQAKHQKHQAFEAELAANKDRIGSVIKMGNKLVE GQQCSGSEDAVQQRIAKLVEEWEFLTSKSKSKSEKLQEANRQRQYTAAVKDLEFWLGEVE HMLDTEDYGKDLATVQNLSKKHALLEADVRAHDDRINDLNQQADSFIDSGLWDVESIKEK KQSINDRYVRVTTLTTHRRQKLDEANTLHQFFRDIHDEEAWIKEKKLLVGSDDFGRDLTG VQNLRKKHKRLEAELNSHEPAIQNVQDIGEKLAAESNLMNDEIQQRLQQLATNWDELKNM AGNRGQKLDESLAYQQFVANVEEEEAWITEKQHLLSGDDIGDTLAAVQGLLKKHDAFETD FQVHRDRSGEVTKEGDKLIAEGNHNADLVRQRCASLNDKMNSLQDTADSRKARLIDNSAF LQFIWKTDVVESWIADKETQVNSDDYGRDLSSVQTLLTKQETFDAGLQAFEKEGIQTITT LKEQLVASNHAQTPAIERRYTDVITRWQKLLGDSDGRKQRLLRLQEQYRQVEDLYLTFAK KASAFNSWFENAEEDLTDPVRCNSVEEIQALREAHEQFKASLSAAEADFNQLAELDKQIK SFNVGPNPYTWFTMEALEDTWRNLTKIIMERDEELAREQQRQEENDVLRKQFAQAANAFH SWLTETRSAMMEGTGTLENQLEATKKKSADVRAQRSQLKHIEDLSAAMEERLILDNRYTE HSTVSLAQQWDQLDQLGMRMQHNLEQQIQACNQSGVSEEALREFSMMFKHFDKDKSGRLE HQEFKSCLRALGYDLPMVEEGQRDPEFEEILDVVDPNRDGVVSLQEYMAFMISRETENVQ SSQDVEAAFRALTSGEKPYITAQELYANLTKEQADYCIQRMRPYEDPKGRNIPDAYDYVG FTNDLFI-CIQCYQCDSNEDHSCPSNQPFDTNLNALIDCNSFEAKVPGTFCMKISQESPG WYSWKKITRRCGSRSDTGVAWGCRWTYEANGVWKETCFCEDRDGCNSSSSIDKDDKDNPQ LVSEYVNEIYDYMRDLERKDINGRMRGILIDWLVQVHNRFHLLQETLYLTVGILDRFLQK TVARKKLQLVGVT----------------------------------------------- -------------------------------------EMAHMHPSEIAAAALCLSMKVLD WSDTLVHYSKYNESDLLPIMKKMATLVKKKLTAIHTKYKSSKFMRISTIPELKSSVLTEI ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------INSRSSYVNVLVTTTQLVPALAKVVLYGLGGVFNIENIYSATKIGKESCFER IVSRFGRKCTYVVVGDGRDEEVAAKNMTWPFWRVTNHSDLAALHHALDLGYL-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------GYALNCMVASQAMTKKVTAPKIACLDFGLMKAKMKMG VQLLVEDPEQLDAMRKRESDITKERVQKILATGANVILTTGGIDDLCLKYFVEAGAMAVR RCLKQDLKRIAKATGAQFLVTMVNLEGEEVFDASYLGTADEVVQERICDDELILIKGPKV RSCSSIVLRGANNFMLDEMERSVHDALCVLKRVLESKTLVPGGGAVEAALSIYLENFATS LSSREQLAIAEFARSLLAIPKQLAVNAAQDSTDLVAKLRAYHNTSQTKPEHKELKWVGLD LYEGIVRDNKKAGVFEPGISKIKSLKFATEAAITILRIDDMIKLAAEEKQGGSYQDALRS GQLDDESARLLVSKNILNELIVEGKDLTVEYTIYNVGNSAAFGVELDDASFPEEYFEVAA GSLHARWNRLGPGNNVSHNVILKALQSAYFNFTSAQVSYQPAENERVIGYSSAPGEGGIM SLRE---XFSSHVIDWAAFAVMTLPSLGIPFLLWHSSKSKYEALKSK------------- -------------------NETVSLVISRQILSELCSKLNSLDKETAQTVCHFTLEKVQP RVISFEEQVAHIRQHLATIYEESQNWREAAAVLVGIPLETAQKQYTNDYKLETYLKIARL YLEDEDPVQAEAYINRASLLQADSQNEQLQIHYKVCYARVLDYRRKFIDAAQRYNELSYR SIVAEDERMTALKNALICTILASAGQQRSRMLATLFKDERCQQLPIYGILEKMYLDR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GLMNLPGRPVAAFDPEGLIFAAGINSE SLKLYDLRSFDKGPFATFKLQQDKDCDWTSVKFSPDGKLILISTNGQVIRLIDAFQGTPL QTFTGFQNHKGIPLEASFSPDSQFVFSGSTDSKIHCWNTETGMKLAVLGGDHTGPVQCVQ FNPKYMMLATACSHMAFWL-----EYIKLEKRGANNNVLLIQLNRPKALNALFDPLMTDV ANALDACENDPEIGCVVITGNEKAFAAGADIKQMQNKKFQEVYITNFLDHWNRISKFKKP TIAAVNGYALGGGCEVAMMCDIIYAGEKAKFGQPEITIGTIPGAGGTQRLTAAIGKSKTM EMVLTGNPISAQEAEKAGLVSKVCPPDQLVDEAVKTAEKISSHSKLIVQMAKEAVNASYE LTLQEGLRFEKRLFQATFATDDRSEGMTAFVEKRPPTFKD >Scoloplos_armiger MSDRKAVIKNADMSEEMQADSVDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSG-----RHFQTSATQRDIDQAAKYIGAGAATV GVAGSGAGIGSVFGSLVIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLILFAF- -------KAPEQNIHRIRITLTSRNVKSLEKVCADLVRGAKEKNLKVKGPVRMPTKVLRI TTRKTPCGEGSKTWDHFQMRIHKRIIDLHSPSEIVKQITSISIEPGVEVEVTIADMDQVM QVVEPAKTFAKDSMRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNII VMATQISKKRKFVADGVFKAELNEFLTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVL GEKGRRIRELTSVVQKRFNFPEGSVELYAEKVATRGLCAIAQAESLRYKLIGGLAVRRAC YGVLRFIMESGSKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGEPTNDYVDTAVRHVLLRQ GVLGIKVKIMLPWDPSGKIGPKRPLPDHVSILDPKEETVPGQPYSEQKGAK------GGS AGGKFRISLALPVGAVINCADNTGAKNLFVIAVGGIRGRLNRLPAAGSGDMIVATVKKGK PELRKKVMPAVVIRQRKSIRRKDGLFIYFEDNAGVIVNNKGEMKGSAISGPVAKECADLW PRIASNASSIRKNRVQKVSLGPQTVEGENVFGVAHIYASFNDTFVHVTDLSGKETMVRVT GGMKVKADRDEASPYAAMLAAQDVAERCKVLGINALHIKLRATGGNKTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDCTRRKGGRRGRRLMGKPRGLRTARKLKNHRREQKWHDKD YKKSHLGTRWKANPFSGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP RDGCLNYIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANTSLLALYKEKKERPRSDTV VTLRTRKFLTNKLLSRRQMIVDVLHPGTATVKKTEVREKLARMYKTTADVVFVFGFKTQF GGGKTTGFGLIYDTLDLAKKFEPKYRLQRHGSRKQRKERKNRQKKVRGVKKSKVGSMGRV PLVNSKTYATPRRPFEKERLDQELKIIGEYGLRNKREVWRVKYTLAKIRKAARELLTLEE KDPRRLFEGNSLLRRLVRIGVLDESKMKLDYVLGLRAEDFLERRLQTQVFKLGLAKSIHH ARVLIRQRHIRVRKQLVNIPSYVVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQAGA AEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMPLAKDLLHPCIEDEKRKCKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCI GCSTVLCQPTGGKARLTEGCSFRRKQHMVRMNVLADALRTLNNAEKRSKRQVLLRPCSKV IIRFLTVMMKHGYIGEFEIIDDH---------------------RFDVPINDLEKWTRQL LPSRQFGYLVLTTSGGIMDHEE----------------GRMHAPGKGISQSALPFRRSVP TWLKLTPDDVKEHIYKLAKKGLRPSQIGVILRDSHGVAQVRFVTGNKILRILKGKGLAPA LPEDLYNMVKKAVAIRKHLERNRKDKDSKFRLILIEARIHRLARYYKTRKVLAPNWKYDS ATASALVAVAELPEVKLFGRWSTEDVQVSDISLTDYIAVKEKYSKYLPHSAGRYQVKRFR KAQCPIVERLTCALMMHGRNNGKKLLAGRIVKHTFEIIHLLTGENPLQVVVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREASFRNIKTIAECLSDELINAAK GSSNSYAIKKKDELERVAKSNR-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----VSAGWDKLVKVWNLTNCKLKTNHYGHTGYLNCVTVSPDGSLCASGGKDGQAMLWD LNEGKHLYTLDG------------------------------------------------ -----------------------------------XXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXX---------------------SVVHFKIKKNTPLRKLMS AYCERTGVKMESMRFRFDGQPINETDTPLQLDMEDGDSIDVFQQQTGGXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXMSDAGGDVQVI--APVGELDINTALQEVLKTALIHDGLTRGLREC AKALDKRKAHLCVLANNCDEPAYVKLVEALCAEHCINLLKIEDSKQLGEWTGLCKIDKEG KARKVVRCSIVVINDYGKES---------------------------------------- ------------------------------------------------------------ -------------------------------------------ELAKMKQEPVKPEEGRA MQEKINAFAYLECSAKTKEGVREVFETATRAALQVKKKKKSKXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------- ---------------------------------------------------RLVRELEKK FSGTHVVFIAQRRILAKPNRKLRRKDKQKRPRSRTLTAVHEAILDDLVFPAEIVGKRIRV KLDGTRLIKVHLDKAQQTNIEHKVDTFTAVYKKLTGKDVNF-------ERGGFRGGFGGR GRGRGRGRGRGKDGDKEWIPVTKLGRLVKDTKIRTLEEIYLFSLPIKEFEIIDFFLGTAL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDFNGHLGLGVKCSKEVATAIRGAIILAKLSV VPVRRGFWGNKIGKPHTVPCKVTGKCGSVLVRLIPAPRGTGIVGAPVPKKLLTMAGIDDC YTSATGQTATLGNFAKAAYAAIGHTYKYLTPDLWKDTVFQKSPYQEFTDHLAKMSGGLEV LGLKEDDVIKFLACGTHLGSTNVDFQMQHYVFKRKPDGVYIINLKKTWEKLLLAARAIAA IENPADVCVISARPYGQRAVLKFASYTGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDP RTDHQPITEASYVNIPVIALSNTDSPIKFVDIGIPCNNKGVHSIGLMWWLLAREVLRLRG TISREVPWEVMVDLFFYRDPEEAEKE---------------------------------- -------MKFNKSVSSSRRKNRARLFGAPSHIRRKLMSSALSKELRTKYNVRSIPIRKDD EVQVVRGHYKGPQVGKVVQVYRKKFVIHIERIQREKANGASVHVGIHPSKVVVVKLKLDK DRKRILEQRAKSRMTGKHTEESIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKEKRQKKSAINEVVTREYTVNVHKRIHGT GFKKRAPQAIKAIRNFAVKQMGTPDVRIDTRLNKHVWSKGVRNIPYRVRVRLARKRNEDE DSVHKLYTLVTYVPTTTFKGSQTVNVDSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------------ ------------------------------------------------------------ -----------------------------EDDDDVPELVDNFDEPSKSEMVRYSLEAENV TKSAKARGSHLRVHFKNTRETANAIKKMHLRRAVRFLKNVTEEKECVPFKRFNGGVGRCA QAKNWGTTQGRWPKKSAEFLLQLLKNAESNADFKGLDTDHLVIEHIQVNRAPKMRRRTYR AHGRINPYMSSPCHIEVILSEREQRIARSKKKKVSQKKLKKQKMMMRDXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXMGISQDRWHKRRKSGGRVNSIRKKRKFELGRPAANTKLGP QRIHTVRTMGGNKKYRALRLDSGNFSWGSEACTRKTRIIDVVYNASNNELVRTKTLVKNC IVQIDATPFRQWYESHYATPLGRKKGAKLSAEEEATLTKRSKKTQKKFDNRRKTAKVETA LEDEFATGKLLACITSRPGQTGRCDGIVLEGKEYEFYSRKMKSRKGRMSLVVPDKFQHIL RVMNTNIDGRRKIPFAMTSIKGVGRRYAHLVCHKADIDTNKRAGELADEDVEKLLTILQN PRQYKIPDWFLNRQKDIKDGKYTQVMANALESKIREDLERLKKIRAHRGLRHYWGLRVRG QHTKTTGRRGRTVGVSKKK----------------------------------------- -------------------------ILFVVNRPDVYKSPASDTYIVFGEAKIEDLSQQAQ MAAAEKFKAEEEVDDTGVEPKDIELVMSQANVSRTKAIRALKNNSNDIVNAIMMGRVRTK TIKKASKVIIEKYYTRMTNDFHTNKRICEEIAIIPSKKLRNKISGFVTHLMKRIQKGPVR GISIKLQEEERERRDNFVPEISAIEEVDPDTKEMLKSLDFGNIPNLQVTQPIS--XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMRELRISKL CLNICVGESGDRLTRAGKVLEQLTGQQPVFSKARYTVRSFGIRRNEKIAVHCTIRGAKAE EILERGLKVREYELRRRNFSATGNFGFGIQEHIDLGIKYDPAIGIYGMDFYVVLSRPGYC VAYKKRRKGRIGPKHMVNKEESMKWFQQKYDGVILPGKXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------------LRYVK SIGLGFKTPREAIDGNYIDKKCPFTGNVSIRGRILSGVVIRMKMQRTVVIRRDYLHYIPK YNRFEKRNKKLSVHCSPCFRDLSVGDVVTVG----------------------------- MVNVPKSRKTFCRGRKCKKHTLHKVTQYKKGRDSLFAQGKRRYDRKQKGYGGQTKPVFHK KAKTTKKIVLKMECTQCKIKKQLAIKRCKHFELGGDKKKKGQMIQFMGRVIRGQRKGAGS VFKCHNKHRKGQPKLRAFDYAERHGYIKGVVKDIIHDSGRGAPLCKVTFRDPYRFKQRTE LFIAAEGMYTGQFVYCGKKATLQVGNILPVSAMPEGTIVCMLEHKTNDRGRIARTSGSYA TVISHNPEAKKTRVRLPSGSKKVLHSANRGMVGVVAGGGRVDKPMLKAGRAYWKYKAKRN CWPTVRGVAMNPVEHPHGGGNHQHIGKASTVRRTTSAGRKVGLIAARRTGRLRGTKNVIQ KAKRTKKVGITGKYGTRYGASLRKNIKKIEISQHSKYICSFCGKEAMK--XXXIWKCKGC KKTVAGGAYVYSTTAAATVRSAVRRLREMKEMGRRPARCYRYCKNKPYPKSRFCRGVPDS KIRIFDLGRKKARVDDFPLCIHLVSDEFEQLSSEALEAGRICANKYLVKHCGKDAFHLRI RVHPFHVVRINKMLSCAGADRLQTGMRGAFGKPQGTVARVDIGQTLMSIRSRDMSRDSCI EALRRAKFKFPGRQKIFVSKKWGFTKFDRADFEVMRADGRLQPDGVNAKYINEHGPFKAW ----KVTKIIGRTGSQGQCTQVRVEFLDDSNRSIIRNVKGPVREGDILTLLESEREARRL RMTKGTSSFGKRHNKTHTLCRRCGRSSYHIQKKRCAQCGYPAKRLRSFNWSEKGKRRKTT GTGRMKHLKIVQRRFNNGFREGTKPKPRKAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGAYKYMQEMYRKKQSDVMR FLMRVRTWQYRQLSKLHRAPRPTRPDKARRLGYRAKQGFVIYRIRIRRGGRKKPVRKGAT YGKPTNMGVNQIKNARSHQAIAEGRAGRHLQGLRVVNSYWIGEDSTYKYFEIILVDPHHK AVRRDAKINWICEATKKHREMRGLTAANRRSRGLGKGHKFTKTIGGSRNMNWKRRSTLQM RRKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-KSSKMLQHINYRMRCTL QDGRVFVGTFKAFDKHMNLILGDCDEFRKVRPKSAKPREEKRVLGL-------------- ------------------------------------------------------------ ---------FKLVLVGDGGVGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTTRGPIKF NVWDTAGQEKFGGLRDGYYIQGQCAIIMFDVTARITYKNVPNWHRDLVRVCENIPIV--- -----QDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPA LAPPEVHMDPTMARQYEEELKRA------------XXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXX------------------------------------------------------- ---------------LANCIRYFPTQALNFAFKDQIKLLFKQKKEDGYAINFGKNIASGG TAGAMSLCFVYSLDYARTRLANDAKSGKGRQFNGLVDVYRKTLKSDGFVGLYRGFMISCV GIVVYRGCYFGFYDTLKPMLLGENAGLMASFALGYVVTISSGLLSYPIDTIRRRMMMTSG EAVKYKGSMDCAVTIIRTEGFMSLMKGAGANILRGVAGAGVLSGFDKFKEVYMAWRLXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMQNEAGDFVDL YVPRKCSASNRIITAKDHASIQMNVAEVDETTGRMTGQYKTYGICGEIRRMGESDDCLSR LAKKDGIIIKMARGRIKHLKRLNAPKHWMLDKLGGVFAPRPSTGPHKLRECLPMAVFLRN RLKYALTYDEVKKIVNQRLIKVDGKVRTDKTYPAGFMDVISIDRTAENFRLIYDVKGRFA VHRISNEEAKYKLCKVKCLKTG------------------------------XXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXX-------------------------------------- ------------------------------------------------------------ -------------------------------------------------DPSGTYHEWKA NAIGRSAKTVREFLEKHYSEEVASEKETIKLALKALLEVVQSGSKNMELAIMKNGEPLKT LESEEVDVYIKEIEKEKEEEAEKKKQK--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------RETYADIGGLETQIQEIKESVELPLTHPEYYEEMGIKPPK GVILYGAPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEENXPS IVFIDEID---------------------------------------------------- ------------------------------------------------------------ ----------------------------------------XXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----KSKK AQESINTRLALVMKSGKFKLGYKQTLQSLRQGKAKLVIIANNTPPLRKSEIEYYAMLAKT GVHHYTGDNIELGTACGRYFRVTTLSIIDPGDSDIIRTMPSS------------------ ---------------------------------LLDILDTAGQEEYSAMRDQYMRTGEGF LCVFAVNNTKSFEDINQYREQIKRVKDADEVPMVLVGNKVDLPARTVETKEGRMLADSYG IPYIETSAKTRQGVDDAFYTLVREIRKFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKIELCV YSGYKIYPGHGKKAIKADGKGYMFLNSKCEASHMMKRNPRKINWTVLYRRKHKKGQAEEV QKKRTRRTTKFQRAITGATLADIMAKRNQKPEVRKAQREQAIRAFKEKQKAKDTAKPRVA AKRMKLNISYPATGCQKLIDIDDEKKLRHFYDKRISAEVESGNLGDEWKGYVFRISGGND KQGFPMKQGVLTTGRVRLLLGKGHSCYRVRRTGERKRKSVRGCIVDANLSVLSLVIIKKG EQEIPGLTDKSIPRRLGPKRASKIRKLFNLSKEDDVRQYVVRRPLKPVTRAPKIQRLVTP LTLQRKRHRSALKKKRITKRREEAAEYAKLLAQRIKEVKERKMERRRSASASKKVKARDL RTKKREDLEKQLLELRQELASLRVNKVTGGAASKLSKIHTVRKSIARVLTVIHQTQKDNL RKFYLPKDLRKKKTRAVRKALTPFEQSIKTRKQLRKERLYPKRKFAVKXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKKRKGMLKFHIE CKYPVEDGIMDVKTFDKFLHERIKVNKKLNNLKSRLTVISDIPFSKRYLKYLTKKYLKKH NLRDWLRVVSSAKDTYELRYFQINNEEDEEDDADXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------- ------------------------------LDSLDHVEVVMAMEDEFGFEIPDADAERLL KPADVVQYICDKMDVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXTAAFDTRFPNQNQTRNCWQNYVDTFRCRKLDDAE QCNYFWKTAQSLCPNEWIEKWEDQRENLAFAGKIXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGQEKIHINIVVI GHVDSGKSTTTGHLIYKCGGIDERTIAKFEKEAQEMGKGSFKYAWVLDKLKAERERGITI DIALWKFETAKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQT REHALLAYTLGVKQMIIGVNKMDSTEPPYSEARFKEIQKEVSAYIKKIGYNPDHVPFVPI SGWHGDNMMNMGWFKNWEVFTGTTLLEALDNISPPSRPTDKALRLPLQDVYKIGGIGTVP VGRVETGTLKPGMVVTFAPAALTTEVKSVEMHHQTLDEALPGDNVGFNVKNVSVKDIRRG NVAGDSKNDPPKECGDFKAQVIILNHPGQIQAGYAPVVDCHTAHIACRFKELLEKIDRRS GKSLEANPAHVKSGDAAIVEMIPQKPMCVESFVDYPPLGRFAVRDMRQTVAVGVIKAVTK RD-ASAKMTKAAQKAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPRQ IQEIKDFLLTARRKDAKSVKIKKNVKFKVRCSRFLYTLVIQDLEKAEKLKQSLPPGLEVK DIKMSKLSRDAINEAIANILTKKRKFTESVELQIALKNYDPQKDKRFSGTVKLKFIPRPK MQVCLLGDEQHCDEAKANHIPFRDVDSLKKLNKNKKLVKKLAKKYDAFLASDSIIKQIPR ILGPGLNKAGKFPTMLTHGEAMNGKVNEVKATIKFQMKKVLCLSVAVGHVHMKHEEIYAN TTLSINFLVSLLKKNWQNVRALYIKSTMGPPHRIFXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXMTE-NIQNFQDPFAEDHDVHIRIQQRNGRKTLTTVQGIPPEYDFKKI VKACKKEFACNGTVVDHAEYGEVVQLQGDQRQHIAAFLKKIGIEEQIKVHGFXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- --------------GLKNCQAEEMVEFSSGLKGMALNLEPDNVGIVVFGNDKLIKEGDVV KRTGAIVDVPTGLELLGRVVDSXXXXIDGKGPLGNKTRQRVGIKAPGIIPRISVKEPMQS GIKAVDSLVPIGRGQREL-XXXXQTGKTAVAIDTIINQKRFN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------QYREVAAFAQFGSDLDAATQQLLNRGVRLTELLKQGQYVPMAVEEQVAVIYAG VRGHLDKVDPSLITKFESEFLQHVKSSQQDLLTRIRDDGQIVPETEAKLKEVVTSFLSGF XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXLVRFLMKLSHETVTIELKNGTQVHGTITGVDVSM NTHLKTVKMTVKNRDPVQVDTLSIRGNNIRYFILPDSLPLDTLLIDDTPKARRRDXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPIVIDARGHLLG RLAATVAKTTLQGQRVVVVRCEGILISGNFYRNKLKMMRFLRKRMNTKPSRGPFHFRAPS KVFWRTVRGMLPHKLTRGKEAMDRMKTFEGIPPPYDKIKRMVVPSALKILRLKHRRKFCQ LGRLSHEVGWKYQDVVTTLEEKRKVKSKAYYAKKKRATKLQEKAKKIVKKQRLIVSMGHX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------QVSLSMSPDVPLVVEYKIGEMG FIRYYLAPKIEDEAE--------------------------------------------- ------------------------------------------------ETLGRIINVIGE PIDERGPVNAKHFAAIHAEAPEFTEMSVEQEILETGIKVVDMLAPYAKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVICLTDDTSKVSLVYG QMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSD------------- ------------------------------------------------------------ ---------------------------WSVARSVQKVLQDYKSLQDIIAILGMDELSEDD KLTVSRARKMQRFLSQPFQVAEVFTGSAGKLVPLKDTIKGFTMIMNGELDHLPEVAFYMV GAIEEVVIKADKLADERMLMPKKNRVAIYEHLFKEGVMVAKKDFYSPKHPEIEIPNLQVI KALTSLKSRGLVKEQFAWRHYYWYLTNEGIQYLRDFLHLPPEIVPATLKRQPQAQDRQDY RKGGGGDKKADVGAGAS------------------------------------------- -------------------------------------------CSVSGPAEVLTEQAVRT AFSLIDFDNNGYVTKEEF------------------------------------------ ------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX MTNPKGVRRGTRYMFSRPFRKRGIIPLSKYMVTFKRGDIVDIKADGAIQKGMPHKVYHGK TGRVYNVTPHAVGVIVNKRVRGDILAKRVNLRIEHVKHSDCRLEFLKRLKANDATKRAAK ARAYVKRQPVGPRPAHYVKTKGNKPQILKPIPYEFVA----------------------- ------------------------------------------------------------ ----EAICPAQAITIEAEAREDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEY STETHEELLYNKEKLLENGDKWEVEIAANLQADYLYRXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX------------------------------------------- ------------------------------------------AVAREVMKKVADDKKMSK KEKDERILWKKNEVADYEATTFSIFYNNALFLMLIVIASFYLLRSFTPTFNYIFAM---- -----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPSYGDLG KSARDLFSKGFNYGFYKGELKTSTEGGAKFTTSGSHNHDSGKVNGSLELKYKWKDYGLEF VEKWNTDNTLGTEITIEDQLAKGLKLSFDTSFAPQTGKKSGKIKAAYKQDYVNTNVDVDF DFAGPTVHGAAVAGYNGWLAGYQMSFDKSKLTRNNFAVGYKAGDFQLNTTVNDGSEFSGS VYQKVNRELEAAVNLSWTAGSNATKFGVASKYSPTDEITFRGKVNNASQIGLSYQQKLRD GITLTLSSLIEGKSFNQGGHKMGLGFEFE-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXMGKFMRPGKVVLILAGRYAGRKAVIVKNYDDGTGDKGYGHALVA GVDRYPMKVIKRMNKKRVKQRSKLKAFIKVYNFNHLLPTRYSVVNLNKNLINKDSFRDPA QRKKAKVEAKLKFEERYKTGKNRWFFTKLRFERSFIMIKPDGVHRGIVGEIIKRFEQKGF KLVSMKFTQATEEHLKKHYADLSSKPFFNGLVKYMASGPVVPMVWEGNVVLTGRKMLGET DPFKSALGTIRGDYCIEVGRNICHGSDSVESAEKEINLWFDKSEQISWQPAEETWVYE-- -PKPAKTAKQAKEKALKAKKAVLRGAHQVRKKKVRTSVSFSRPKTLYKARQPKYPRKSIP NKNILNQFKIIKYPLTTESAMKKIEDNNTLVFVVEKRANKAQIKNAVKKLYNIDVSKVNT LIRPDGDKKAYVRLAPDYDALDTASKIGVIMPTKQRMRIANEKHSKNVANRGNVPKTLKS AEEKYPVGPWLLGLFVFVVCGSAIFQIIQSIRMXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----EHIELHRKR QGYRLDYHERKRKKESRAAHEIAHKAKKLRGIKAKLFSKKRHSEKIQMKKTIKMHDERKT KQKSDDNVPEGAVPAYLLDREGQTRAKVLSN----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------MAARPLVTVYNEKGEGTTTHVALPWVFRAPIRPDIVSFVHSEMRKNTRQPYAV SVKAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRSGRMFAPT--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXMTEQMTLRGTLQGHGGWVTQIATTPQYPDMILSASRDK TLIMWKLTRDTNYGVPQRRLHGHSHFVSDVVMSSDGQFALSGSWDHTLRLWDLSTGQTTR RFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIEDCHTEWTSCVRFSPNT NNPIIVSCGWDKLVKVWNLTNCKLKTNHIGHSGYLNCVTVSPDGSLCASGGKDGQTMLWD LNEGKHLYTLDGGDKINALTFSPNRYWLCAATGPSIKIWDLEGKIVVDELRQEVISTSAE PPQCISIAWSSDGQTLFAGYTDNLIRVWVVSV-------RLVMLGSTGVGKSALVVRFLT KRFIWEYDPTLECTYRHQALVDEESISSEILDTAGNEDGICINEGHVRWGDGFILVYSVT DRDTFLEIQQMKQQLDEIKRPKSSICALIGNKTDLEHQRCVSTLAADMCCAFFETSANGD DNINEAFHEIFREVKRR----MSEEKKDSSEHINLKVTGQDNSVVHFKIKKNTPLRKLMS AYCDRTGLKMGAMRFRFDGQPINEQDTPLVLEMEDGDSIDVFQQQTGGXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX--DAEGDDV----VGAGAMDINTALQEVLKTSLIHDGLARGLHEC AKALDKRQAHLCILANNCDEPMYVKLVEALCGEHGINLLKVDDNKKLGEWAGLCKIDKEG KARKVVGCSCVVVKDYGKETQALDVLNDYFKSKKMAAIRKKLVIVGDGACGKTCLLIVFS KDQFPEVYVPTVFENYVADIEVDGKSVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSI DSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDDSTKRELMKMKQEPVRPEDGRS MADKISAYSYLECSAKTKDGVREVFETATRAALQTRKKKKGGXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----AKIIKPQGEKPDEFESSISQ ALLELEMNSDLKAQLRELYISAAKEIDVAGKKAIIIFVPVPQLRAYQKIQIRLVRELEKK FSGKHVVFIAQRRILPKPTRKTRTKSKQKRPRSRTLTSVHNNILEDLCYPAEIVGKRIRI KLDGSRTIKVHLDKNQQTTVEHKLDTFTAVYKKLTGKDVNFEF-----XXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXCQKSEFLVNGKYRLVRKIGSGSFGDIYLGINI QNGEEVAVKLESHKARHPQLLYESKLYKILQGGVGIPHIRWYGEKDYNVLVMDLLGPSLE DLFNFCSRRFTMKTVLMLADQMIGRIEYVHNKNFIHRDIKPDNFLMGIGRHCNKVFLIDF GLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRGS LPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLR QLFRILFRTLNHQYDYTFDWTMLKQKAAAAMNVEKLKQRIGGKGTARRKKKVVHRTATTD DKKLQTSLKKLAVNNIPGIEEVNMIKEDGQVIHFNNPKVQASLAANTFAITGHAEQKQIT DMLPGILNQLGAESLSNLKKLATVTDDIDDDEDDVPDLVENFDEASKGEMARYSSDPENA TKAAKARGSHLRVHFKNTRETAKNIKKMHLHKAVRYLKNVTDKKECVPYRRFNGGVGRCA QAKNFKATQGRWPQKSAEFLLQLLKNAESNAEYKGLDTDHLVIEHIQVNRAPKMRRRTYR AHGRINAYMSSPCHIEVILSEREQAVAKTAKKKVSQKKLKKQKMKMQD-KTGPKPELTEE QKQEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIADIDKEGSGTIDFND FLXMMTQKMSEKDSKEEILKAFRLFDDDETGKISFKNLKRVAKE---------------- --------------------MGISRDKWHKRRKTGGRQEPLRKKRKFELGRPAANTKIGA RRIHTVRTRGGNKKYRALRLDIGNFAWGSEAQTRKTRIIDVVYNASNNELVRTKTLVKNC IVQVDSTPFRQWYEAHYALPIGRKKGAKLTETEEAVLNKRSKKTQKKYDERKKIAKVETA LEEQFTTGRVLACIASRPGQCGRADGYVLEGKELEFYLRKIKSKKGKMSLVIPEKFQHIL RVMNTNIDGRRKIPFAITAIKGIGRRYAHVVLKKADVDTTKRAGELSDEDVDKVITIMSN PRQYKIPDWFLNRQKDVKDGKYSQVMSNALDNKLREDLERMKKIRAHRGLRHYWGLRVRG QHTKTTGRRGRTVGVSKKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKWEY KEEHPFEKRRAEGEKIRKKYPDRVPVIVEKAPKARVGDLDKKKYLVPSDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGALYQEHHEEDFFLYIAYSDESVYGMRDLRIRKL CLNICVGESGDRLTRAAKVLEQLTGQQPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAE EILERGLKVREYELRRGNFSDTGNFGFGIQEHIDLGIKYDPGIGIYGMDFYVVLGRPGFN VAERRIKRGRVGFKHKVRKDESMKWFQRKYDGVILPGKMGLKFLEFVRPFCAVIPEIAKP ERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSSDPFYWLRVILASNRGTLMELGIS PIVTSSLIMQLLAGAKIIEVGDTPKDRALFNGSQKLFGMVITIGQAIVYVMTGMYGEPAE IGAGVCLLIVLQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVN TGRGTEFEGAVIALFHLLATRQDKVRGLREAFYRQNLPNLMNLMATIFVFAIVIYFQGFR VDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYLISQMLAAKFSGNFFVNLLG VWADVGGGGPARSYPVGGLCYYLSPPETLGHVGEDPIHAMLYIVFMLGSCAFFSKTWIDV SGSSAKDVAKQLKDQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFMGAIG SGTGILLAVTIIYQYFEIFVKEQSEMGGMSTLLFQTERAFQKQPTVFLNKKRSLLLRYVK SVGLGFKTPREAIEGHYIDKKCPFTGDVSIRGRILTGVVTKMKMQRTIVIRRDYLHYVRK YNRFEKRHKNMSVHLSPCFRDVQPGDVATVGECRPLSKTVRFNVVKVTKGTGAKKGFTKF XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRVIRSQRKGPGS IFVAHTKHRKGAAKLRAVDYAERHGYIKGVVKDIIHDPGRGAPLAKVVFRDPYRYKLRTE TFIATEGMYTGQFLYCGKKATLQVGNILPVGVMPEGTIVCCMEEKAGDRGRLARASGNYA TVISHNPDTKRTRVKLPSGCKKVMPSANRAMVGIVAGGGRIDKPMLKAGRAYHKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGHASTVRRDTSAGRKVGLIAARRTGRLRGSKQITG KXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------------------- ------------------------------------------------------------ -----------------------------------------IGQPIMSVRGREGDRAHII EALRRAKFKFPGRQKIHVSRKWGFTKWDKANFEEMRADGRLVPDGVGVQYRPSHGPLQRW ----RVTKVLGRTGSQGQCTQVRVEFLDDSNRSIIRNVKGPVREGDILTLLESEREARRL RMTKGTSSFGKRHNKTHTICRRCGRSAYHIQKKRCASCGYPNPHKRQYNWSEKSKRRRTT GTGRIRHLKVVFRRFRNGFREGTVAKPRRK------------------------------ -------------------KCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDXVDR GYYSVETVALLVSLKVRFKERITILRGNHESRQITQV--------XXYGNANVWKYFTDL FDYLPLTALVDSQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGW ------------------------------------------HDRNVVTIFSAPNYCYRC GNQAAIMELDDALKYSFLQFDPAPRRGEPHVTRRTPDYFL---YKYMQELYRKKQCDVMR FLLRVRCWQYRQLSAIHRASRPTRPDKARRLGYRAKQGYCIYRIRVRRGGRKRPVPKGAT YGKPTNQGVNQLKFQRSLQSVAEERVGRRCGGLRVLNSYWVAEDSTYKFFEVIMVDTFHK AIRHDAKVNWICNAVHTHREMRGLTSAGKKSRGLGKGHSFHQTIGGSRRACWKRNTMFSI RRKR-------------------------------------------------------- ------------------------HPNVYPSGTVCLSLLDEEKDWRPAVTIKQILLGIQE LLNEPNIKDPAQAEAYTIYCQNKVEYERRVREQASRFRDPT-GRSSKMIQHVNYRMRCSL QDGRTFIGTFKAFDKHMNLILGDCDEFRKVRPKSSKAREEKRVLGLVLLRGENLVSMTVE GPPPAEDGMSRVPLPGQ-HGPGMGRAAGRGIS-GGGLQGPVRGVGGPSHQMMQPQ--MMG GG--QEPVQFKLVLVGDGGVGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPVKF NVWDTAGQEKFGGLRDGYYIQGQCAIIMFDVTARVTYKNVPNWHRDLVRVCENIPIVLCG NKVDIKDRKVKAKAIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPA LLPPEVQMDPLLAKQYEDELQVAQTVALPDDDDDLNDGIKQYYVSKIEEIQLVVTEKTQN LRRLEAQRNELNAKVRMLREELQLLQEQGSYVGEVVKPMDKKKVLVKVHPEGKFVVDLDK NIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEI KEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ KFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRLESGSGGDSEVQRTMLELLNQLD GFEPQQNIKVVMATNRIDILDSALLRPGRIDRKIEFPAPNEEARLDILKIHSRKMNLTRG INLRKIAEMMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFELAVAKIMLKDSEKNMSI KKQWKLSFAESFGLSGAAAVISKTAAAPIERVKLLIQNQDEMMKQGRLTEPYKGVVDCTM RTYRNEGILPFWRGNMANCIRYFPTQALNFAFKDQIKAMFKASKTDSNALKFSKNIASGG AAGAMSLLFVYSLDYCRTRLANDAKAAGKREFNGIVDVYRKTLKSDGVQGLYRGFVISCV GIIVYRGCYFGFYDTLKPILLGEDASLLASFALGYVVTISAGLVSYPIDTIRRRMMMTSG QAVKYKGSIDCALQILKNEGAMSLMKGAGANILRGVAGAGVLAGFDKFKALYVQWRLMSD CSDLDRQIEQLRRCEIIKEGEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLK ELFRVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITILRGNHESRQITQV YGFYDECLRKYGSITVWRYCTEIFDYLSLSAIIDGKVFCVHGGLSPSIQTLDQIRAIDRK QEVPHDGPMCDLLWSDPEDTNGWGVSPRGAGYLFGSDVVAQFNAANDIDLICRAHQLVME GYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQRDFTIFEAAPQESRGKPQADYFL VRLPPEVNRILYIRNLPYKITAEEMYDIFGKYGAIRQIRVGTTPETKGTAFVVYEDIFDA KNACDHLSGFNVCNRYLVVLYYQSNKAFKKIDQEKKREEIDKMKQKYGLSTPE--MSIGV PIKVLHEAEGHVVTCETKTGEVYRGKLIEAEDNMNCQMSNITCTYRDGRVAQLENVFIRG SKIRFLILPDMLKNAPMFKRVGAGRGKSAILRAAARGRGRA--------MQNEAGEYVDM YIPRKCSASNRIINAKDHASIQINFAEVDESTGRMTGANKTYAICGAIRRQGESDDCLIR LAKKDGII---MRGPKKHLKRLNAPKHWMLDKLGGVFAPRPSTGPHKLRECLPLMVFLRN RLKYALTYDECKKILFQRLVKVDGKVRTDKTYPAGYMDVITIEKTAENFRLIYDVKGRFS VHRITGEEAKYKLCKVKRVSVGPKGVPFIVTHDGRTIRYPDPLVKVNDTVRV---QDDHY DYIWKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDAKTIKAQIWDTA GQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADNNIVIMLVGNKSDL RHLRAVPTDEAKAFAEKNNLSFIETSALDSTNVETAFQNILTEIYKIVSQKTIRDSPDDN NVQTIHVAPT------------MTSRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVR GKDVVVLGVEKKAVAKLQEDRTVRKIALLDDHVAMAFAGLTADARILINRARVECQSH-- -------------------------------------------------------FAWKA TAMGKNFVNGKTFLEKRYSETLE--EDAVHTAILTLKESFQMTEDNIEIGVCNQD-GFRR LSPSEVKDYL-----------------GGGQGGDKKDDKDKKRKYEPPIPTRVGKKKKKI KGPEAANKLPQVTPHTRCRLKMLKLERIKDYLLLEEEFIKNQERLKPQEEKQEEERSKVD DLRGTPMSVGSLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDSLEPGCSVLLNHKVHAVV GVLSDDTDPMVTVMKLDKAPQETYADIGGLDQQIQEIKESVELPLTHPEYYEEMGIKPPK GVILHGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPS IVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSKGDVKVVMATNRIETL-XA LIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTLADDVNVEEYVM--------------- ------------------------------------------------------------ ------------------------------------------------------------ -NKMAPALRKVYDQMPDPRWVISMGSCANGGGYYHYAYSVVRGCDRIIPVDIYVPGCPP- AEALLYGVLQLQKKVKRMNIAQQWYRKSDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYA NNSNYKNDTMIRKEAFVHKSVMEELKRVIEDSEIMQEDDNVWPNPDRVGRQELEIVIGDE HISFTTSKIGSLVDVNQSKDPEGLRTFYYLVQDLKCLVFSLIGLHFKIKPIXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMTEYKLVVVGAGGVGKSA LTIQLIQNHFVEEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGF LCVFAVNNNKSFEDINQYREQIKRVKDADEVPMVLVGNKVDLPTRQVDQKPAKALAESYQ IPYIETSAKTRQGVDDAFYTLVREIRKFMGERYNIHSQLEHLQSKYIGTGHADTNKWEWL TNQHRDSYASYMGHFDMLNYFSLVENEAKARVKFNLMEKMLQPCGPPPERPED------- --------------------SFQFLNGKCAKAHMMKRNPRKINWTVLYRRKHRKGQTEEV SKKRSRRTTKFHRAITGASLSDIMAKRNQKPEVRKAQREQAIRAAKEKTRAKD------- ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKVKAREL HGKKKEDLLKQLEDLKQELLNLRVAKVTGGAASKLSKIRIVRKSIARVLTVINQTQKDNL RKFYKPKDLRPKKTRAIRQALTKHESSIKTKKQQRKDRLYPVRKYAVKAAKKGPKVTDKV FFDIEIGGEKAGRIVIGLFGKTVPKTVANFKSLADGFQTFKGSKFHRVIKDFMIQGGDFT RGDGTGGKSIYFKDENFKLKHYGAGWMSMANAGKDTNGSQFFITTKKTDWLDGRHVVFGK VLEGMNVVRKIESTKTDGDRPQNDVVIADSGSLKVEEPFAVAKEPSDNXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------------- ------------------------------------------------------------ ------EIPEFPIAPEIALELLMAANFLDCVLMIRKADLENHNKDGGLWMVIHGKVYDVQ DFKSQAPCGSEKLTEYAARNATEAFEAACHTQE--------------------------- --------------MSYMLQHLHNGWQVDQAILSEEDRVVVIRFGHDWDPTCMVMDETLY RCAEKVKNFCIVYLVDISKVPDFNKMYELYDPCTSMFFYRNKHIMIDLGTGNNNKINWCM EDEQEFTDIVETVFRGARKGRGLVVSPKDYSTKYRYKRLQRQLEFLEVQEEYIKDEQKNL KKEYLHAQEEVKRIQSVPLVIGQFLEAVDQNTGIVGSTTGSNYYVRILSTIDRELLKPSA SVALHKHSNALVDVLPPEADSSITMLQADEKPDVAYADIGGMDIQKQEVREAVELPLTHF DLYKQIGIDPPRGVLMFGPPGCGKTMLAKAVAHHTTASFIRVVGSEFVQKYLGEGPRMVR DVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTVNVKVI MATNRADTLDPALLRPGRLDRKIEFPIPDRRQKRLIFSTITGNMNLSEEVDLEDYVARPD RITGADINAICQEAGMQAVRENRYVVLAKDFEKGYKNNIKKDETEHEFYK----LTFDII RERVLLVLKLYDKIDPEKLTLDSHFMNDLGLDSLDTVEVIMAMEDEFGFEIPDADAERLL KPADIVQYIADKEDV--------------------------------------------- -------------------------------------------------TQALILSPTRE LATQIQKVILALGDYMSVQCHSCIGGTNIGEDIRKLDYGQHVVSGTPGRVFDMIRRRNLR TRAIKMLILDEADEMLNKGFKEQIYDVYRYLPPATQVVLVSATLPHEILEMTSKFMTDPI RILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKM REANFTVSSMHGDMPQKEREAIMKEFRSGASRVLITTDVWARGLDVQQVSLVINYDLPNN RELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLIMALRRP FDPVAHELEQNFRLTKFADLKGGCKVPQDVLLKLLEGL-QAQDSEQSHFQYVAAVPRIGI GMDCCVTPLRHGGLSLVQTTDFFYPLVDDPYMMGKIACANVLSDLYALGVTECDNMLSLL AVSTKMTDKERDVVMPLMLRGFRDLAEEAGTSVNGGQTVMNPWLTVGGVATTVCQPNEFI TPDNAVVGDVLVMTKPLGTQVAVNAYSWLDQPERWNRIKLVVSEDDTRKAYQRAMFSMAR LNRTAARLMHKYNAHGATDITGFGLLGHANNLAKIQKNEVGFVIHNLPVIAKMASVAKAC GQMFGLLQGVSAETSGGLMIALPREQAAAFCKDIEKQEGYQAWIIGIVEKGTRTARIIDK PRVIEVPAKEKDLLVSVSQSVHAYFINIDAHAEECFFDKVSSGTKMSLMFEVAEGGFLDI DVKIIGPDGKSIYSGDRESNGKYTFAAHMDGVYKYCFSNRMSTMTPKIVMFSMDLGEKPK AHHNKLEDMINELSTSLTGVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFESLVLVAMT LGQIYYLKRFFEVRRIV------------------------------------------- ------------------------------------------------------------ -----------------FHTEQMYKHKLVDFIINFMEEIDKEISDIKLAVNSRARISAEE FLKMFSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEIMVDDRLV TMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTMPNTFKTLDSWRDEFLIQASPRDPEN FPFVVIGNKIDLENRAVSTKRAQSWCHSKGDVPYFETSAKEAINVEQAFQTVAKNALAQE TDVELYNEFPDQIKLTNEQNSEGCGCTAPFDARFPNQNQTRNCWQNFIDYYRCQKIEDYA PCEYFKMCYTSMCPDEWVEQWTDHMESGSFAGKVMPDYLGTDQRKVKDDDKKDKPIQSLD EGDIALLKTYGAGMYSRSIKGVEEDIQNVLKRVNELSGIKESDTGLAPPALWDLAADKQT LQSEQPLQVARCTKIINADSDDPKYIINVKQFAKFVVDLGDQVAPTDIEEGMRVGVDRNK YQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVEVPLLHPERFVNLGI EPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMART KKACIIFFDEIDAVGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDT LDPALMRPGRLDRKVEFGLPDLEGRSHIFKIHARSMSVEKDIRYELLARLCPNSTGADIR SVCTEAGMFAIRARRKMATEKDFLEAVNKVIKAYAKFSSTPRYMTYNMGQEKVHINIVVI GHVDSGKSTTTGHLIYKCGGIDERTIAKFEKEASEMGKGSFKYAWVLDKLKAERERGITI DIALWKFETKKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKSGQT REHALLAYTLGVKQLIVGVNKMDNTAPPYSKDRFNEITKEVSTYIKKIGYDPKTVAFCPI SGWHGDNMLKMTWFGGWKKANGFTLFDALDSINPPKRPTDKPLRLPLQDVYKIGGIGTVP VGRVETGTLKAGTVVTFAPAGIATEVKSVEMHHQTLEKAEPGDNVGFNVKNVSVKDIRRG NVAGDSKNDPPKEAANFDAQVIILNHPGNIVKGYTPVLDCHTAHIACKFFELKEKIDRRS GKKLEEHPDKLKSGDSAIVNMVPSKPMCVEAFSDYQPLGRFAVRDMRQTVAVGVIKKVEK KD-GSTKVTKAAQK-ELEQLRQESEQLKNQIREARKAAADTTLVQVANQIEPVGRIQMRT RRTLRGHLAKIYAMHWGCDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAP SGSYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDNQIVTSSGDMTCA LWDIETGQQTTSFTGHTGDVMSLSLSPDMKTFVSGACDASAKLWDIRDGMCKQTFSGHES DINAIVFFPNGHAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLG GYDDFNCNVWDTLKQERAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKIWNMSYAYLF KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES FRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLEARR DVKKEEGEAFAREHGLIFMETSAKTAANVEEAFINTAKEIYQKIQDGVFDINNEANGIKI GPQHSPANPSGGGSGNQGGGMTRGRTELGDVTIHNIKQLKRLNQVVFPVTYNDKFYKDVL EVGELAKLAYFNDIVVGAVCCREDKSDNQRRLYIMTLGCLAPYRRYGIGSVMVQHVLKIC EEDGNFDNIYLHVQINNEGAIKFYEKFGFEIVEKKDNYYKRIEPADAYVLQKTLR-XXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- ------------------------------------------------------------ ----------KFPTMLTHNESMVSKVDDVKATIKFQMKKVLCLSVAVGHVTMTPDELVSN VNMSINFLVSLLKKNWQNVRALYIKSTMGPAQRVYMSEADKLNIDSIIARLLEVRGSRPG KNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLNAGRPVTPPRGSAKNK GKMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXX----------------------------------------------- ------------------------QLQGDQRNNVATMMTKGGLLDQVKVHGFSALFNFQS LLTVVLLLICTCAYIRSIAPRMLDKNKEGVLGIFWKCARIGERKSPYVAVCCVAMAVSIL FFSSSRITSVLARHLPRAVAKQSALGAGFVSCRNVSTTAEVSTILEERILGAPKANLEET GRVLSIGDGIARVYGLKNIQAEEMVEFSSGLKGMALNLEPDNVGIVVFGNDKLIKEGDTV KRTGAIVDVPVGEEILGRVVDALGNPIDGMGPLGVATRARVGVKAPGIIPRISVKEPMQT GIKAVDSLVPIGRGQRELIIGDRQTGKTAIAIDTIINQKRFNDAAEEKKKLYCVYVAIGQ KRSTVAQIVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCAMGEYFRDNGKHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDDFGGGSLTALPVIE TQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTKAMKQVAG SMKLELAQYREVAAFAQFGSDLDQATQNLLNRGVRLTELLKQGQYVPMAIEEQVVILYAG VRGYLDKIDPSKITTFEKEFTKHILGSQQDVLKTIREENEISPATDAKLKEIVINFIAGF MEAIYRVPYTVLECPNIKLKRPSWVKQPSAMFMFGIVLASYFLVTGGIIYDVIVEPPSIG STTDERGNTKPVAFMPYRVNGQYIMEGLASSFLFTLGGLGFIILDQTNKPTTPKLNRILL LSVGFVCILVSFFTCRVFMRMKLPMPKVKRSRKPPPDGWELIEPTLDELDQKMREAETDP HEGKRKVEA-XPIFRLHHQRSRYLYDLFYKRKAISRELYEYCLRENIADKNLIAKWKKQG YENLCCLRCIQSRDTNFGTNCI--------------------------EYAQVTKMLGNG RLEAMCFDGTKRLCHIRGKLRKKVWINASDIILIGLRDYQDAKADVILKYSPDEARNLKA YGELPESAKINE--------------LVRFLMKLSHETVTIELKNGTQVHGTVTGVDVS- ---XKAVKMTVKNKDAVQLDTLSIRGNNVRYFILPDSLPLDTLLIDDAPKGRGRN----- ------------------------------------------------------------ -------------------------KDRYISKMFLRGDSVILVLRNPLPIIIDARGHLLG RLASIVAKTILQGQRVVIVRCEEINISGNFYRNKLKYLSFLRKRCNVRPSRGPFHFRAPS KIFWRTVRGMLPHKLSRGKEAMDKMKVFEGVPPPYDKQKRLVIPAALKVLRLHPRRKFCR LGRLSHEVGWKYQNVVATLEAKRKVKSKVFYERVKKERQLREQAAKIAPYQQVIESYG-X XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--MQQTVAAIKPDAYKE EIMDKIREAGFRIAARKETELSKDMAEQFYKDVEDKEYYDELVEHMTSGKTLFMVLSRED AVDGWRSLMGPTDPEQAKDANPDSIRAQFGHDVKANAVHGSSNKEHADAAIHQIFGEL-- ------------------------------------------------------------ -----LLKKVLDSIKDLLSDGTWDCSGTGMSLQAMDSSHVSLVSLMLRCDGFDTYRCDRN MTMGINLGSMSKILRCAGNDDAITIKAGDNADTVTFMFESPNQEKVSDYEVKLMDLDTEH LGIPETDYSCVVKM-----------------------------------LGTGNVKLAQT ANVDKEEEAVTIEMQEAVTLTFALRYLNFFTKATPLSPQVTLSMSADVPLVVEYKFADMG YVRYYLAPKIEDNEDG-------------------------------------------- ------------------------------------------------------------ ---------------------------------------------------------AGV GKTVLIMELINNIAKAHGGYSVFAGVGERTREGNDLYHEMIQTGVIDLKGDNSKVSLVYG QMNEPPGARARVCLTGLTVAEYFRDAEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIA ELGIYPAVDPLDSTSRILDPNVVGSEHYTIARGVQKILQDHKSLQDIIAILGMDELSEED KLTVTRARKIQKFLSQPFQMAEVFTGKTGRFVPLKETIKGFSEILEGKWDHLPEIAFYMV GAIEEVAEKAEVLAEEQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXMGKQNSKLKPELLDDLRQNTEFNDDEIQEWYKGFLKDCPSGNL SVDEFKKIYGNFFPYGDASKFAEHVFRTFDTNGDGTIDFREFICALSVTSRG-------W AFSMYDLDGNGYISRQEMLEIVTAIYKMVGTVMKMPEDEATPEKRTDKIFRQMDKNLDGK LSLAEFIEGAKSDPSIVRLLQCDPMSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNL TGLNEQVPHYRQALDMILDLEPDDELEDNPNTSDLIEQAAEMLYGLIHARYIMTNRGIAQ MIDKWQQGDFCYCPRVYCENQPMLPIGLSDVPGEAMVKLYCPKCQDVYTPKSSRHHHTDG AYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPKAYQLQYQ-------------- XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQCRSNYKNVSPDEDNTDVSTISD NVASHIFYSELVKGFSVVGSHMFKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAICPAQAITIDAETRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEY STETHEELLYNKEKLLENGDKWEAEIAANLQADHLYR----------ETKNNHENDKEQQ EAIEQIDEVQNEIDRLNDNASEEILKVEQKYNKLRQPHFQNRSELIAKIPNFWVTAFVNH PQVSALLNEEDEEALQFLTKVEVQEFEDIKSGYRINFNFDTNPYFENKLISKEFHLNSSK SSTITWKTGKDLTKKSKKRSHEEQESFFGWFGDHGDAGADELGEVIKDDIWPNPLQYYLA SEIEDDGADEEGIDEEEKKLTKEEELLLQDFSRNVTTKSWALFYGNAFIVSAIPIWLFWR IHQMDPYILFTVVTLVSTYLVAFAYKNVKFHLKHKIAQKREEAVSRHVMKQVSDDKKMSK KEKDERVLWKKNEVADYEATTFSIFYNNASFLVLVIIASFYVLRSFSPTVNYLVSIGSAA GLLALLSTSN-ATQGKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQT VCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVKELQRQ ASPNIVIALAGNKADLRMVEYDEAQAYAEENSLLFMETSAKTAMNVNDIFLAIAKKLPKN EQGVDLRENG--EYLASIFGTEKDKVNCSFYFKIGACRHGERCSRLHNKPTFSQTMLMQN LYLNPQNTAQVQVTDVEVQQHYDEFFEEIFVELQLKYGEIEEMNVCDNLGDHLVGNVYVK FRYEEDAEKAVNDLNTRWFNSRPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKP ISRELRRELYGHNRRSRSRSPPTRRSPNRSSNRERRRSRSPRRRSMFLTRSEYDRGVNTF SPEGRLFQVEYAIEAIKLGSTAIGIQTSEGIVLAVEKRVTSPLIEPSSIEKIMEVDNHIG CAMSGLIADSRTMIDRARVEAQNHWFTYNEKMTVESVTQAVSNLALQFGDDDADPGAMSR PFGVALLFAGIDSKGPQLFHMDPSGTFIQYDAKAIGSGSEGAQQALQEVYHKAMTLKEAC KHALTILKQVMEEKLNSTNVEMARVTPEKMFHMFTKEELEDVIKEIAQKTWDMSNSMENV SSVDDIYRYDKKQQQDILTAKPWEKDPHYFKYIKISALALLKMVMHARSGGNLEVMGLLL GKVDGNTMIVMDSFALPVEGTETRVNAQAQAYEYMAAYTESAKQVARLENAIGWYHSHPG YGCWLSGIDVSTQMLNQQFQEPFVAIVVDPVRTISAGKVNLGAFRTYPKGYKPPDEGPSE YQSIPLNKIEDFGVHCKQYYSLDVSYFKSSFDRKLLESLWNKYWVNTLSSSSLITNADYM TGQIFDLAEKLEQSEAQLGRGGFMEKKSEDKLAKATKDGCKNTIEALHGLMSQVIKDKLF NQVGGLPRRIIKETQRLQAEPVPGIDAKPDDSNARYFHVVVAGPNDSPYEGGTFALELFL PEEYPMSAPKVRFMTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPD DPLANDVAEQWKVNEIQAIETARTWTRLYA------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------PMEVYVDDDSKLTLHGLQQHYVKLKDNEKNRKLFELLDVLEF NQVIIFVRTVQRCMALAQLLVEQNFPAIAIHRAMAQEERLQRYQQFKDFQKRILVATNLF GRGMDIERVK--FNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDETDAKVPPCYGDLG KSSRDLFSKGFNYGFYKLECKTKTSTGVSFTSSGSQNQDTSKSAGTLETKYKWNDYGLTF TEKWNTENILGTEITIEDQIANGLKLTFDTSFAPTTGKKSGKIKTAYKREYLNLNCDVDF DFAGPTIHGAAVLGYNGWLGGYQMSFDKSKLAKSNFAVGYTADDFTLHTNVNDGAEFGGS IYQRVNSDLETGVNLSWTAGTNATRFALGAKYTPDKDATFRAKINNSSQIGLSYQQKVRD GITLTLSSLIEGKNFNQGGHKIGVGFDLE-DSVREKALSDYRKKLLETKELEARLKEMRE QLKEFTKQYDKSENDLKALQSVGQIVGEVLKQLTEDKFIVKATNGPRYVVGCRRQLDKVK LKAGTRVALDMTTLTIMRYLPREVDPLVFNMSMEDPGDISYAQVGGLGEQIRELREVIEL PLLNPELFQRVGITPPKGCLLYGPPGTGKTLLARAVSSQLDANFLKVVSSSIVDKYIGES ARLIREMFGYARDHQPCIIFMDEIDAIRRFSEGTSADREIQRTLMELLNQMDGFDALGQV KMIMATNRPDTLDPALLRPGRLDRKIEIPLPNEQARMDILKIHAAPIAKHGEIDWEAVVK LSDDFNGADLRNVCTEAGMFAIRAERDYVIEEDFMKAVRKVGDNKKLESKLDYKPVMPET LRSTLTKFYDEYMNTTSKKLKIVDAYLFYILLTGIVQFVYCCLVGTFPFNSFLSGFISTV GSFVLGVCLRLQVNPQNKIDFAGIGPERAFADFVFAHIILHLVVINFIG----------- ---DKCIGSRIHIIMKNDKEIVGILMGFDDFVNMVLEDVTEFESTPEGRRVTKLDKILLN GNNITMLVPGGEGPEVIDHYENPRNVGSMDKGDKTVGTGLVGAPACGDVMKLQIKVDENG KIIDAKFKTFGCGSAIASSSLATEWIKGKSLDEASSIKNTEIAKELSLPPVKLHCSMLAE DAIKAALKDYKKKN-MLVLVLGDLHIPHRCNSMPGKFKKLLVPGKIQHILCTGNLCTKES FDYLKTLASDVHVVRGDFDENLNYPEQKVVTVGQFRIGLCHGHQVVPWGDTESLAMLQRQ LDVDILITGHTHKFEAFEHENKFYINPGSATGAYNPLDS-ITPSFVLLDIQQSTVVAYVY QLLGDDVKVERIEYKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXERTFIMVKPDGVHRGLVGETIKRFEQRGY KLVAIKIMQASEDHLKKHYADLSTKPFFTGLVKYMASGPVVPMVWEGEVVKMGRQMLGET NPLQSKPGTLRGDFCVDIGRNIVHGSDAVESAKKEISLWFKDEELVSWKPCADSWVYEXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMATKQRMRVANEKHSKNILTRGNVPKSLKP PEEKYPVGPWLLALFIFVVCGSAVFQIIQSIRFVKVKSWTAVATWRWVANDDNCGICRMP FDGCCPDCKMPGDDCPLVWGECSHCFHIHCIVKWLNSQQVHQLCPMCRQEWKFKEMIRFI LIQNRAGKTRLAKWYMHFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIVYRRYAGL YFCICVDVSDNNLAY-----------------------------------EMFLAGEIRE TSQTKVLKQLLMLSSLE--TIFSKILDKTIPADIIHEDEQCIAFRDVNPTAPTHFLVIPR KPIPGISEDTMLLGHLLYTAKTIAAKEEGYRIVINDGSNGSQSVYHLHLHVIGGRQMQWP PMGGLFSYFSGLFGTKERRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVTYKN LKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSMDRDRIGISKQELVSMLEEDELKKAI LVVFANKQDIEGAMTVTEVANALGLSSMKNRKYQIFKTSAIKGEGLDEAMEWLANTITQA KGLYFHIGETEKKCFIEEIPDETMVVGNYKVEMYDKAKNEYIPTISGLGMHVEVKDPEGK ILMSRTYAAEGRFTFTSHTAGEHSVCLHSNSTAWFGGTQLRVHMDIQVGEHANDYQQIAA KDKLTELQLRVRQLLDQVEQIQKEQNYQRYREERFRQTSESTNQRVLWWSIAQTLILLLT GFWQMRHLKSFFEAKKLVMFYHVSLEHEILLHPRYFGPNLLNTVKQKLFTEVEGTCTGKY GFVIAVTTIDNIGAGIIQPSRGFVLYPVKYKAIVFRPFKGEVLDAVVTQVNKVG------ ------------------------------------------------------------ ----------RLYCKAVFTGFKRGLRNQHENTALLKIDGVNTKDETEFYMGKRCAYVYKA RNKTACPGHDKSSRIRVIWGKVTRSHGNSGGVRAQFSKNLPPKAMGRRIRIMLY------ ----------------------------NTTFISTIGIDFKIKTVELGGKKIKLQIWDTA GQERFHTITTSYYRGAMGIMLVYDITNAKTFDNISKWLRNIDEHANEDVEKMILGNKCDM NDKRQVSKERGDSIAREHSIPFLETSAKTNINVEKGFMDLAQAILNKMPQNEHIELHRKR HGYRLDYHERKRKKEGRMAHEASQKAKKLRGIRAKLYNKKRHSEKVQMKKTLKMHEEKKT KQKSNDDVPEGAVPAYLLDREGQSRAKVLSNMIKQKRKEKAGKWDVPLPKVKGVSEAEVF KVVKTGKTRRKAWKRMVTKACYVGEGFTRKPPKYERFIRPMALRFKKAHVSHPELKATFC LPIIGVKKNPSSPMYTALGVITKGTVIEVNISELGLVTQAGKVIWGKYAQVTNNPENDGC INAVLLVMAARPLISVYNEKGESSDSNVTLPAVFRAPIRPDIVSFVHSEMRKNTRQPYAV SKKAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRR INVNQKRYAICSAIAATGVPALVMSKGHRIEQIPEVPLVLSDKIEEYKKTKEAVGLLKHL KAWSDIEKVYNSKRFRAGKGKMRNRRRIMRRGPLVIYNKDNGICRAFRNIPGVTLINVAH LNLLKIAPGGHVGRFCLWTESAFKKLDSIYGTWRKSSKEKTNYNLPMPKMTNSDLTRLLR SEEIQKALRAPKTDTQKKVMKRNPLKNRRAMLRLNPFDAVAKRTSKRKADRQKAADQRRG IVTVDTGGKPRPR----GSGEQELATKTLQIQSKRFYLDVKQNRRGRFIKIAEVGSGGKK SRLLLAMSTAADFRDHLTEFSEHYASLGPPNPDNLPEDGKLKSEVMIKDNRRYYLDLKEN QRGRFLRVSPRSQQRSQIAIPAQGMIEFRDALTDLLDEFGTDDHESQGELPEPRSMRVEN KMFYFDVGQNRRGVFMRISESNFRTAVTIPERSWARFRDVLSDFVDK--------QMRAT INQKLIETGERERLKELLRTRLIECGWRDQLKAYCKEVVKQKGLEHITVDDLVSEITPRG RALVPDQVKKELLQRIRTFLAQQSNMNIRCAKPEDLMNMQHCNLLCLPENYQMKYYFYHG LSWPQLSYVAEDEKGNIVGYVLAKMEEDPED-VPHGHITSLAVKRSHRRLGLAQKLMDQA SLAMVEAFKARYVSLHVRKSNRAALHLYASTLKFEINETEPKYYADGEDAYAMKRDLT-- ----MSHTILLVQPGRKPEGRTYSDYESLNECLEGVCKIYEEYLKRMNPNSPSITYDISQ LFDFIDQLADLSCLVFQKNTGTYVPHNKDWIKEKIYVLLRKQAGKMSEQTEEKKVEEVKR -IHTYPLIRHSDMNDEMKTEAMELCVTACEKFSNNNENAAKCIKDTMDKKFGASWHVVVG EGFGFEITHEVKNLLYMYFGGNMAITVWKCSMSHRKFSAPRHGSLGFLPKKRSRRQRGKA KAFPKDDASKPIHLTAFLGYKAGMTHLVREVDRPGSKLNKKETVEGVTIIETPPMVIVGV VGYIETPRGLRTFRTVFAQHLSEECRRRFYKNWYRSKKKAFTKYSKKWQDDQGKKEIEKD LAKMKKYCKVIRIIAHTQMKLMKKRQKKAHIMEIQVNGGTIAQKVDWAREHLEKQVPITD VFDKDEMIDTIGVTKGKGFKGVTSRWHCKKLPRKTHKGLRKVACIGAWHPSRVGFSVARA GQKGYHHRTEINKKIYRIGQGIHTKDGKVIKNNASTDYDLTEKTITPMGGFPHYGEVNND YVMIHGCCAGPKKRVITLRKSLLVHTKRKAMEKINLKFIDTSSKFGHGRFQTPQEKQSFM GPLKKD------------------------------------------------------ ------------------------------------------------------------ ------------------------YPQGLAMTKEIGAVKYLECSALTQKGLKMVFDEAIR AVLCPKPKPKKKRMCTVLIFDSGL--KKKKKTPFDLDGALDEISLDDNLTKKKKKKKKVF DMDEIGDSLPKTETSLPSKKKKSNTDRDYTYDELLNRVFDIMREKNPDMVAGEKKRFVMK PPQVMRVGTKKSSFSNFAEICKMLHRQPKHLLAFLLAELGTSGSVDGNNQLIIKGRFQQK QIESVLRRYIKEYVTCHTCRSPDTILQKDTRLFFLQCETCGSRCSVASIKSGFQAVTGKR AAIRAKTT---------------------------------------------------- ------------------------------------------------------KIEIEI KINHEGEVNRARYMPQNPCVLATKTPSSDVLVFDYTKHPSKPDPSGECQPELRLKGHQKE GYGLSWNPNLNGNLLSASDDHTICLWDINTTPREGRCIDAHTIFTGHTSVVEDVSWHLLH ESLFGSVADDQKLMIWDTRSNNTSKPSHTVDAHTAEVNCLSFNPYSEFILATGSADKTVA LWDLRNLKLKLHSFES---XIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQSAEDA EDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEEPDTPAS ELEMPAPSRARVYADVNTHRPRDYWDYESHAVEWGQQDDYQIVRKLGRGKYSEVFEAINI TNNDKCVIKILKPVKKKKIKREIKILENLRGGTNVISLVAIVKDPVSRTPALIFEHVNNT DFKQLYQTLTDYDIRFYLFELLKALDFCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLA EFYHPGQEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPFFHGHDNY DQLVRIAKVLGTEELYEYIDKYQI------------------------------------ -------------------------------RVPESLLKKRKQNAEKNRDKRRVMFKRAE KYVKEYRVKERDEIRLVREARKTNNFYVPAEPKLAFVTRTRGINGIHPRPRKIMQLFRLR QINNGTFVKLNKATLNMLRIADPYITWGYPNLKSVKELVYKRGYGKIEGRRIPLADNALI EKKLGQYGIICMEDLVHEIFTVGSHFKQANNFLWTFKLNTPNGGWRKKNNHFVDGGDFGN REDKINNLLKKMMQFMLLFSRQGKLRLQKWYVPHADRLKKKITRELITTILSRKPKMCSF LEWRDLKIVYKRYASLYFCCAIEQDDNELLTLEIIHRYVELLDKYFGSVCELDIIFNFEK AYFMLDELLLGGEVQETSKKNVLKAIAAQDLLQEETPQGFFEDHGLGMSKAHPPELKKYM DKKLCLKLNGSRTVTGILRGFDPFMNLVVDEAIEETKAGEKNSIGMVVVRGNSIVLLESL DRI----PLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTI RLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFQQTSKWIDDVRTERGSDVIIM LVGNKTDLSDKRQVSTEEGERKARELNVMFIETSAKAGYNVKQLFRRVAAALPGMEQTEP KKMIEVKLKDTPAEPQQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- ------------------DGELWVQRLKEEYQSLIKYVQNNKEADNDWFRLESNKEGTRW FGKCWYIHELLKYEFDIEFDIPVTYPTTAPEIALPELDGKTAKMYRGGKICLTDHFKPLW ARNVAKFGIAHAMALGLGPWLAVEIPDLISKGAV----SLLDFDFLDDVRRMNKRQLYYQ FLNFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNHREEPIRVGE IVVFKIEGREIPIVHRVLKIHEKEDGKIKFLTKGDNNSVDDRGLYAPGQLWLEKKDVVGR ARGFVPYVGIVTILMNDYPKFKYAILALLGIFVLIHREISTMNPEYDYLFKLLLIGDSGV GKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYR GAHGIIVVYDVTDQESFNN----------------------------------------- -----------------------------------------------------------E ESLGEEVLRMSTDEVVSRTRLLDNEIKIMKSEVMRISHELQSQKEKIKENTEKIKVNKTL PYLVSNVIELLDVDPQDQGEEDGGNIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKL TPGDLVGVNKDSYLILETLPQEFDSRVKAMEVDERPTEQYSDIGGLDKQIQELIEAVVLP MTHKERFETLGIQPPKGVLLYGAPGTGKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGA KLVRDAFALAKEKSPAIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNSD IKVIAATNRVDILDPALLRSGRLDRKIEFPTPNEEARARIMQIHSRKMNVSTEVNYEELA RCTDDFNGAMCKAVCVEAGMIALRRGATELSHEDYMDAIMEVQAKKKTNLQYYAKDAADQ NFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRQDKRVKLQIWD TAGQERYRTITTAYYRGAMGFLLMYDVTNEESFNAVQDWCTQIKTYSWDNAQVVLVGNKC DLEDERVVSHDRGKQLADQLGLEFFETSAKENINVKAVFERLVDIICDKMSESLDSDPTQ TKRLTENPNPQNSGCQCLNTHKMAITRNYISQPRLTYKTVSGVNGPLVILDNVKFPKFAE IVNLTLNDGSKRAGQVLEVSGSKAVVQVFEGTSGIDAKHTTCEFTGDILRIPVSEDMLGR VFNGSGKPVDKGPPVCAEDYLDIQGQPINPWSRIYPEEMIQTGISAIDGMNSIARGQKIP IFSAAGLPHNEIAAQICRQGGLVKVPGKSVMDDHEDNFAIVFAAMGVNMEIARFFKQDFE ENGSMENVSLFLNLANDPTIERIITPRIALTTAEFLAYQCEKHVLVILTDMSSYAEALRE VSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLT GYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRDDHSDVSNQLYACYAIG KDVQAMKAVVGEEALTPEDLLYLEFLQKFEKNFIAQSHYENRTIFETLDIGWQLLRIFPK EMLKRIPAEKLAKYYPRDS-GPGFVGIKFCQECNNMLYPKEDKENRVLLYACRNCDYQQE ADNQCIYVNKITHEIDELTQIVADVIADPTLPRTDDHPCPECQHKEAVFFQSQTTRSEEG MRLYYVCTSPNCAHRWTEKPAFKVADVSLAEWGRKAIEIAENEMPGLVSMRKDYGPKKPL KGARIAGCLHMTVQTAVLIETLLELGAEVQWSSCNIFSTQDHAAAAMAKRGVAVYAWKGE TDEEYIWCIDQTLVFPDGKPLNMILDDGGDLTNLVHSKYPEYLEDIKGLSEETTTGVHNL YKMMSKGMLKVPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGKVAIVGGYGDV GKGCATALRAFGARVIVTEIDPINALQAAMEGYEVATMDEACKEARIFVTTTGCKDIITQ RHFEQMQEDSIVCNIGHFDCELDVAWLNENCKHKENIKPQVDRYTLKNGRHIILLAEGRL VNLGCAMGHPSFVMSNSFTNQVLAQLELWTKTDQYKVGVHILPKKLDEEVAAAHLEHLGV KLTKLTDDQAGYLGIPQEGPFKPDHYRYADDQEQAPVNNVEEPLDLVRLSLDERIYVKMR NDRELRGRLHAYDQHLNMVLGEVEETVTTVEIDEETYEEIYKSTKRNIPMLFVRGDGVIL VSPPMRT--SSNVENLSPQVIRQLAKELSDLASNPPEGIKVFPNEEDITEIQATIEGPSG TPYSGGQFRMKLILGKNFPAEPPKGFFLTKIFHPNVAKNGEICVNTLKKDLKP------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------PKIYANEGMT GFYKGLVPLWCRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFTAGYIAG VFCAIVSHPADTIVSKLNNDKGSNFVQVAQKLGFAGLWKGLFPRIIMIGTLTALQWFIYD SVKVACRLPRPPPPEMPESLKRKL-HWKTERILAVALLGIIPSTFIYPADLVVTGVCLHV FWSLDGVTNDYMHVAALGYASLLYFIFNDVGIGGAAHMLW---NEQQEEDASELQFPKEF ENAETLLVSEVQRKQQNESAEEEQELSEVFMKTLNYTQRFSRFKNRETIAAVRSLLMQKK LHKFELAALANLCPESAEEAKALIPSLEGRFEDDELQSILDDIQTKRSFQYNLQPHLAKQ DLSTLDVAKLNPLTPEIISRQATINIGTIGHVAHGKSTVVKAISGVQTVRFKNELERNIT IKLGYANAKIYQCDNKSCPRPVCYRSCGSSKEDTFPCDRSGCGKFRLVRHVSFVDCPGHD ILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQ AKDQYDQILKFVQGTVAEGAPIIPISAQLKYNIEVICEYIIKKIPIPIRDFTSEPRLIVI RSFDVNKPGCEVDDLKGGVAGGSILRGVLKVGQEIEVRPGIVSKDKEGKLTCKPILSRIV SLFAEQNDLQFAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPDIYTELEISYFLLR RLLGVRTEGDKKGAKVQKLSKNEILMVNIGSLSSGGRVLAVKADLAKIGLTSPVCTEIGE KIALSRRVEKHWRLIGWGQIRRGVTVKPMAELLLDSDIRFWVFLPIVIITFLIGIIRHYV TILLSSEKKVELTQIADSQILIRSRMLRENGRFIPRQAFLLRKHFFNAEGTGFF------ ------------------------------------------------MLQRGVELASLD ASWVSSASWYFLNVFGLRSMYNLILGQDNAADQTKVMQDQMSGAAMAMPPDPTKAFKAEW E-------------------MFLWDWFAGILNFLGLYKKSGKLVFLGLDNAGKTTLLHML KDDRMAQHVPTLHPTSEELTMGGMRFTTFDLGGHQQARRVWKDYFPAVDGIVFLVDAFDR ERFVEAKSELDSLLTDEQVANAPVLILGNKIDIPGAASEDEIRHMFGLHGQSTGKGTVSR SELRPMELFMCSVLKRQGYGEGFRWLAQYIN------------NWCNWPDESFEEMDSTL AVQQFIQQAIRRDFSNIDDILTPPEGQDEGVWKYEHLRQFCMELNGLAVKLQMDCNPETC TQMTATEQWIFLCAAHKTPKECPAIDYTRHTLDGAACLLNSNKYFPSRVSIKESSVAKLG SV-------------------------------------------------------MPN IKLQSSDGEIFDVDVEIAKQSVTIKTMLEDDEDEEEPVPLPNVNAAILKKVIQWCTYHKD DPPPPEDDENKEKRTDDISSWDADFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMI KGKTPEEIRKTFNIKNDFTPAEEEQVRKENEWCEEKXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------- -----------------DMSCVDKFMTLLLNMEEEGNISPIIQHGNITFVYIKYNNLYLV ATSKKNANVALVFSFLHKIVQVFVEYFKELEEESIRDNFVVIYELLDELMDFGYPQTTDS KILQEFITQEGHKLEVAPRPPMAVTNAVSWRSDGVKYRKNEVFLDVIESVNLLVSASGNV LRSEIVGAVKMRVYLSGMPELRLGLNDKVLFESTGRGKSKSVELEDVKFNQCVKLSRFDN DRTISFIPPDGEFELMSYRLNTHVKPLIWVESIIERHAHSRVEYMIKAKSQFKRRSTANN VEIVIPVPADADSPKFKTTVGSCKYVPDQNAVIWTIKSFPGGKEYLMRAHFGLPSVLGED SEGKPPIHVRFEIPYFTVSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRTQMGVLER ISEIESEMARTQXNKATSGHLGLLKARLAKLRRELIEPKGGGGGVGEGFDVAKTGDARIG FVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDG KGRGKQVIAVARTCSLIYIILDVLKPLQHKKLIEHELEGFGIRLNKEPPNIVFRKKDKGG INLQSMVTQSELDLDLVRMVLGEYKIHNADITLRYDATAEDLIDCVEGNRVYVPCIYVLN KIDQISIEELDVIYKVPHCVPISAHHKWNFDDLLEKMWDYLSLVRIYTKPKGQLPDYNSP VVVKSGASTVEDFCNKLHRTIVKEFKYAIVWGSSVKHQPQRVGKEHQLHDEDVVQLVKK- AKHHPDLIFCRKQPGVAIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGSYQGRCVIC GGPGVSDAYYCNECTIMEKDRDGCPKIVNLGSAKTDLFYERKKYGFKKRPNLPPISGDKL LAKTELRKVPVPANRYTPLKENWLKIFTPIVEHLHLQVRFNLKSRNVEIKSCKETKDIGA LQKATDFVKAFTLGFEIEDSLALVRLDDLYLESFEITDVKPLKGDHLARAIGRIAGKGGK TKFTVENVTKTRIVLADTKIHLLGSFQNIKIARTAICNLILGSPPSKVYGNMRAIASRSA ERRIDVKNPVVELDGDEMTRIIWEKIKDKLVFPYVNVESLYYDLGLPYRDATDDQVTIDA AHAIKKHSVGIKCATITPDEQRVEEFNLKKMWLSPNGTIRNILGGTVFREPILCESIPRL VPGWKKPIVIGRHAFGDQYKATDFVVSNPGTFELVFTPADGSETRHKAFEFKDGGGVCMG MYNTDESITGFAHSCFQYALQKQWPLYMSTKNTILKRYDGRFKDIFQEIFESTYQKDFDN AGIWYEHRLIDDMVAQVLKSEGGFVWGCKNYDGDVQSDIVAQGYGSLGLMTSVLLCPDGK TVEAEAAHGTVTRHYREHQKGNPTSTNPIASIFAWTRGLEHRAKLDDNPELARYCHIMEK ACVDTVESGKMTKDLAGCIHGLKNVKPEHYLYTMDFLDAIAEEFN--------------- ------------TVLYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWR HYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMKPHEI QEKLGLTRIRDRNWYVQPACATTGDGLYEGLTWLTSNAKSXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXKVQEVREVTRIERIGAHSHIRGLGLDDALEARNVSQGMVGQMPARRAAGIILEMI KEGKIAGRAILIAGHPGTGKTAIAMGMAQALGQDTPFTSIAGSEIFSLEMSKTEALTQAF RKSIGVRIKEETEIIEGEVVEIQMDRPATGTGAKVGKLTLKTTEMETVYDLGQKMIESLT KEKVQAGDIITIDKATGKITRLGRSFTRARDYDAMGAQTRFVQCPEGELQKRKEVVHTVS LHEIDVINSRTQGFLALFSGDTGEIKAEVREQINSKVAEWREEGKAEIVPGVLFIDEVHM LDIECFSFLNRALESDMSPILIMATNRGITRIRGTQYQSPHGIPIDLLDRLLIISTTPYD EKEIKQILRIRCEEEDVEISDDALVVLTRIGMETSLRYSIQLITTANLVSRRHKGTEVSV DDIKRVYSL----------------------MAEFDLTTRMGQYLDRHLVFPLLEFLSVK EIYDESEMLKGKLDLLSNTNMVDFAMDVHSQLYPDQDVPTSLKDKRRNVVEELKRLQSQV EPIIKIFEDPEVMIQTSRDGKALFDSLARSHDFKSEMLDTLYKFAKFQYECGNYSGAAEY LYFVRVLVPPGDKNALAALWGKLASEILMQDWDAALEDLNRLREVVDGGLQSLQQRTWLI HWSLFVFFNHPKGRDLIIDMFLYTPQYLNAIQTMCPHILRYLTTAVITNKTVLKDLVKVI QQESYTYRDPITEFLECLYVNFDFDGAQQKLRECETVLVNDFFLVACLDDFIENARLFIF ETFCRIHQCISISMLAEKLNMSPDEAERWIVNLIRNARLDAKIDSKLGHVVMGAQAVSPY QQVIEKTKGLSFRSQMLAINIEKKL----MGVEVETTEPGDGQTFPKQGQTVIVHYTGTL TNGKKFDSSKDRGKPFKFKIGKSEVIRGWDEGVAQMSVGQRAKLTCSPDYAYGAKGHPGV IPPNATLVFDVELIGIQMPKYYCDYCDTYLTHDSPSVRKTHCSGRKHKENVRLYYQKWLE EQVXXXXXDTTAAFKAGKIAQNPFQNGGAMIPPPASLTGPPGGPMMHMMGPPGPGHMPPM RPPMGPMGPHMPMMRPH--LTLERDIQRAIELLDHLQRSGEVNKLAALQKVLQSEFCTAV REVYEHVYETVDITGSPEVRANATAKATVAAFAASEGHAHPRVVELPKTEEGLGFNVMGG KEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGVSVEGEPHEKAVDLLKAAQGSVKLV VRYTPKVLEEMEARFDKQRSARRRQVACLLGVTLSDPTTYFKEEFWNDRWVASTNKGSEA GDFKWSAGKFYGDAEKDKGIQTSQDVRFYALSAKFE-PFSNEGKTLVIQFTVKHEQNIDC GGGYVKVFGKDLDQKDMHGESPYHIMFGPDICGPGTKKVHVIFTYKGKNLLTKKDIRCKD DVFTHLYTLIVRPDNTYEVKIDNAKVESGELEADWDFLPLKKIKDPEAKKPDDWDEREKI DDPEEKKPEDWEKPEHIADPDAKKPEDWDDEMDGEWEPPMIDNPEYKGEWKPKQIDNPAY KGKWIHPEIDNPEYTADSNLYKYDDFSNIGFDLWQVKAGTIFDNVLITDDEKFAEEHGKE TWEKTKDGEKKMKDQQDEEERKKQEEEDKKKKEEEDAKKDEDKDXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--VFRLIGDLSHLFAIILLLIRI WRTRSCAGLSGKSQIMFAMVFTSRYLDLFTTFVSVYNTTMKSIFILLSFATVFLMYMKFK ATYDSNHDTFRMEFLIVPVGGLSFLVNHEFSPLEILWTFSIYLESVAILPQLFMISKTGE AESITSHYLFALGSYRALYLLNWVYRYYFEGFFDLIAIVAGCVQTILYCDFFYLYITKVL KGKKLSLPAMKIEEVKSTTKTQRIATHSHIKGLGLDESGYAHQNAAGLVGQELAREAAGV IVDMIKCKKMAGRAVLFAGPPGTGKTAIALAIAQELGSKVPFCPMVGSEVYSSEIKKTEV LMENFRR----------EVYEGEVTELTPVETENPMGGYGKTVSHVVIGLKTAKGTKQLK LDPSIYESLQKEKVEVGDVIYIEANSGAVKRQG--------------------------- ------------------------------------------------------------ ---------------------------------------------------DLVSPHGIP LDMLDRLMIIRTLPYSQDEMQQIICVRAAIENIDIADESLQQLGEIGV--TLRYSVQLLT PSSLLARINGKDAITKEDIEEINELFYDAKSSAKILAEQEDKFMKDFQVDEEGDRGLQKL KEKARRRKGRGF-TRSGVQEYEAMEVGGPGPQRSVEGWILFMTNVHEEAQEDDIMDKFAD ------------------------------------------------------------ ---MSYQLYRNTTLGHTLQESLDELIQCGQITPQLALKVLLQFDKAINNALASRVKNRIN FKGHLNTYRFCDNVWTFVLNDVEFRTVNKVKIVACDGKSTFMFTSESVGEGHPDKICDQI SDAVLDAHLRLDPNAKVACETCAKTGMIMLLGEISSTANVDYQKIVRDTVKYIGYDCSEK GFDYKTCNVLVALEEQSPDIAQGVHVDRDEAEIGAGDQGLMFGYATDETDECMPLTVVLA HQLNAKIAELRRNGSMPWARPDSKTQVTCEYKIVKGACIPIRVHTVVISVQHSLEIKVDD LRAELMEKVVKSVIPKKYLDDKTVYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAH GGGAFSGKDFSKVDRSGAYAARWVAKSLIQAGLCKRVLVQISYAIGVAEPLSITVFSYGT SNKSEKELLQIIKNNFDLRPGAIVKNLNLKRPIYQKTAAYGHFGRSEFPWEQPKKLTFMA GSALKRLMAEYKQLTLNPPEGIVAGPVNEENFFEWEALIIGPESTCFEGGVFTAMLTFPS DYPLSPPKMKFTTDLFHPNIYPDGRVCISILHAPGDDPMGYETSAERWSPVQSVEKILLS VVSMLAEPNDESAANVDAAKTWRDDRKKFEEIAHRTVRKSLGLXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------LDNMSDADIMGTNIPTGIPLVYELDADLKPIKHYYLASEEQVK AAMDKVAAQGKAK----------AEYIETASGNKVSRQSVLCGSQNIVLNGKTVIKADCI IRGDLANVRIGRHCVISKRAVIRPPFKKFSKGVAFFPLHIGDHVLIEEDSVVNA---XXY VHIGKNCVIGRRCVLRDCCAIADNTVLPPETVVPPFTLFSGSPG---------------- ---------------------------------GLDYNEWLVTHTISLFEHINLMYGTIS EYCTSTSCLSMNGPANTQYLWLDEKG--KKCKCAAPQYVDYVMTFIEKTIREETVFPAKF GQIFPVSFESIAKKILRLMFHVIAHIYHAHYRDIVNLGLHGHLNCVFQHFMTFNRRFNLL EEK----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------------------- ----------------------------------------------------SRLGHPFI RDGATIRVVLQLLRERFNVYVTEKSGNKMHNDLMALGIPTVVVLDSAVGYVMEKVDLVLV GAEGVVESGGIINKGTYGMSICAKAMNKPFYVVAESFKFTRIYPLN-QDVPNEFKYQASR EHPLVDYTPPAYITLLFTDLGILTPS-----------MIIPIRCFSCGKVIGNKWEAYLG LLQAEYTEGDALDALGLKRYCCRRMLLSHVDLIEKLLNYAPLEK---------------- ------------------------------------------------------------ ------------------EEELANLRSQQRAFEELRNAELVEEQRLEEQERRHREEKERR MKQQREILRKERETADKIAARAFSQSYLADLVPSVFGTLADNGYFYDPVERDVEQGFMPW LMDRVEEQLNKSMLGRLVVDGLLREVVRERGSLYQKXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-AKDEMRQFWKVNQKRPVSPWWIYKPEL TSMLSLQHRITGIVMGIVVNLAAITLVALPYDLTTLMTMLKDQQLNPALLFSLRFILCYP LTYHYINGMRHLAWDAGKGFALKEVYSSGKFVIASIPYF--SVALSAYRDQHFKGSRGEQ ERQLIYTTTLYIGNMSFYTSEEQIYELFGKCGDVKRVIMGLDKAKKTPCGFCFVEYYTRE EAENSMRYVNGTRLDDRIIRTDWDAGFKEGRQYGRGKSGGQVRDEYRTDYDSGRGGYGKL LQDKI------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------ENVKYCIFANFSVTGG KWIVSGSEDNMVYIWNLQTKDIVQKLPGHTDVVLCCACHPSENIIASAALENDKTIKLWR SDVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVAIGIAALLL ILCCCFCICKKCCKRKKKDDKKKGPKGTVDLKSVGLLGSSYKEKXQPDLDELEVNMEDNE DAESTKSEVKLGKLQFSLDYDFQKGELQVGVIQGADLPGMDMSGTSDPYVKVYIMPDKKK KFETKVHRKTLNPVFNETFTFKVPYAEIGSKTLVFAIYDFDRFSKHDQIGLVKVPLNSID LGRVVEEWRDLTSPESDSEKENKLGDICFSLRYVPTAGKLTTVILEAKNLKKMDVGGLSD ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -SAVYKELVKLIDPGVKAWTPTKGRSNIIMFVGLQGSGKTTTCTKLAYHYQRKGWKTCLV CADTFRAGAFDQLKQNATKARIPFYGFLTKGSEQESMARLKKLMTVMDS----------- ----------------------NDSELDSHE--GAKLFTRGRVQRVARGAGVSVREVQEL LTQKFAQMVKKMGGIKGLFK-GGDMGKNVPTQMAKLNQQMAKMMDPRVLQQMGGMSGLQN MMKQFQQGAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMTSKDYYFDSYAHFGIHEEMLKDEVR TLTYRNSMYHNKHLFKGKVVLDVGCGTGILCMFAAKAGAKKVIGIECSSIVEHAQNIVKA NHLDDVITLVKGKVEEVTLPDGIEKVDIIISEWMGYCLFYESMLNTVVYARDKWLKPGGL IFPDRATLFICAIEDRQYKDEKINWWDSV------------------------------- -----------------------------------------FTKCHKRTGFSTAPDAQYT HWKQTDEYLTVKKGEEMFGTLTMKPNKANNRDLDITVDVDFKGELSEMVETMHYKMRMVK EDKTTWKSNYFMKIIQLLDDYPKCFIVGVDNVGSKQMQQIRISLRVLMGKNTMIRKAIRG HLENNPSLERLLPHIKGNVGFVFTKKDLVEVRDKILSNKVAAPAKAGATAPLDVKIASQN TGLGPEKTSFFQALAIPTKIARGTIEILNEVHLIKIGEKVGASESALLNMLKI------- ------------------------------------------------------------ --------------------SAQKGRLIAVIGDEDTCTGFLLGGIGELNKHRQPNFLVVD KNTSVSEIEEAFKSFVNRDDIAVVLINQNIAEMIRYVIDVYEEPVPAVLEIPSKDHPYDA SKDSILRRAKGMFSVEEMRGNEVTLPMELCSNFDADEIKRLGKRFRKLDLDNSGSLSVEE FMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKESKLRFAFKIYDMD KDGYISNGELFQVLKMMVGSNLKDAQLQQIVDKTIFHADADGDGKISFEEFCSVVGNMDV HKKMVVDVMTFITSWDDFAKAAEKLYVADPVNSRFTIKYRHCEGQIVIKMTDNRECLQYR TEHAQDVKKLEKLTSQLMRHMASK-LYEEVKLYRTAREREKYDNMADLYAVINTLQCLEK AYIKDSVTPKEYTAACSKLLVQYKAAFKQVQGDEFPTVDYFMKKCKLDCPAAMDRIKEDR PITIKDDKGNTSKCIADIVSLFITIMDKLRLEIRAMDEIHPDMRELMETMNRLSILPADY EGKAKVSQWLQTLGGMQASDELTDAQVRQMLFDLESAYNAFNRILHNMLSSLVKEHQLKQ QARKEIQEKKKKEAAAATALTHALVDHLNAGVAQAYVNQKKLDTETKILQANATQLAKQT IQWLKLVEDFNQSLKEIGDVENWARSMETDMRTISSALEYAYK----------------- ------------------------------LRSSITPGTVLILLAGRHKGKRVVFLKQLS SGLLLVTGPYHLNGCPLRRINQIYVIATKTKIDISGVKLPDRLNDEYFKRKRQK--PQAK GDIFEFKKEEYSVNSERKEDQVEVDRQILDVVRKHEDKKYMFGYLGAMFSLKNKQYPHQM VFLEWLFGKKKTPAEMLRQNQRALNKAMRDIDRERAGMERNQTKIIADIKKMAKQGQMDA VKTMAKDLVRQRAYVKKFILMKANIQAVSLKIQTLKSNNTMAEAMKGVTKAMMAMNKQM- ------------------------------------------------------------ -----------------------------------NLYCDFCLGDHEENKKTGQKEELVS CADCGRSGHPSCLQFTDNMIVSVKKYPWQCIECKSCGLCGTSDNDDQLLFCDDCDRGYHM YCLNPPLLEPPEGNWSCHLCIEEFH----------------------------------- -----FEKIGMRRAVEGVLIVHEHGLPHVLLLQLGTTFFKLPGGELRETEDQVEGLKRLL TETLGRPDGGPMDWSIEDTIGNWWRPNFEPPQYPYIP--------------------ALF AVPRNYKLVAAPLFELYDNSAGYGPIISSLPQTLSRFNFNFHMTPSGTTPTGAKAMGMAT PTPGHLMSMTPEQMQAYSWQREIDERNRPLSDEELEAMFPPGYKVLQPPAGYVPIRTPAR KLIATPTPMAGTPGGFRMQVHIVDMQPKGNLPMMKPDDMQYFDRKIMKLLLKIKNGTPPM RKAALRQITDKSREVGAGPLFNQILPLLMSPTLEDQERHLLVKVIDRILYKLDDLVRPYV HKILVVIEPLLIDEDYYARVEGREIISNLAKAAGLATMISTMRPDIDNMDEYVRNTTARA FAVVASALGIPSLLPFLKAVCKSKKSWQARHTGIKIVQQISILMGCAILPHLKNLVEIIE HGLVDEQQKVRTITALALAALAEAATPYGIESFDSVLKPLWKGIRQHRGKGLAAFLKAIG YLIPLMDAEYANYYTREVMLILVREFQSPDEEMKKIVLKVVKQCCATDGVEPQYIKDEIL PPFFTHFWNQRMALDRRNYRQLVDTTVEIAHKVGASEIISRVVDDLKDEAEQYRKMVMET IEKIMANLGAADVDSRLEEQLIDGILYAFQEQTTEDVVMLNGFGTVVNALGKRVKPYLPQ ICGTILWRLNNKSAKVRQQAADLISRIAIVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLG SILGALKSIVNVIGMTKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGSEFVS AREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVC TTVAIAIVAETCSPFTVLPGLMNEYRVPELNVQNGVLKSLSFMFEYIGEMGKDYIYAVSP LLEDALMDRDLVHRQTSMAAIQHIALGVFGFGCEDALIHLMNYVWPNIFETSPHVVQAFM GAIEGMRVGLGPCKVLQYAMQGLFHPARKVRDVYWKVYNTIYIGAQDAMIPAYPRITNDD KNQYIRYELDYVL----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------EYEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGIN PFDSQEAKPYKNDPEILAMTNLVSAYQNNDINEFEKILKTNRRNIMEDPFIREHIEDLLR NIRTQVLIKLIKPYTRIHIPFISKELNIDVTEVESLLVSCILDNTIHGRIDQVNQVLELD QGVARYSALDKWTTQLQSLHQAIINKMAVLLMGKSGSGKTSMRSIIFANYIARDTRRLGA TIDVEHSHVRFLGNLVLNLWDCGGQEAFMENYFASQRDNIFRNVEVLIYVFDVESRELEK DMHYYQSCLEAILQNSPDAKVFCLVHKMDLVQEDQRELIFREREEDLKRLSKPLATSIWD ETLYKAWSSIVYQLIPNVQQLETNLKNFGDIIDADEVLLFERATFLVISHCQRKQHQDVH RFEKISNIIKQFKLSCSKLAASFQSMEVRNSNFAAFIDIFTSNTYVMVIMSDPSIPSAAT LINIKNARKHFEKLERIDQ------RLFSVLRFESVIHEFDPYFNYRTTRFLTEEGFYSF HNWFDDRAWYPLGRIIGGTIYPGLMVTSATFY-VLNFFNITINIRNVCVFLAPFFSSLTT LVTFLLTKELKDSGAGLV---------GYISRSVAGSYDNEGIAIFCMLFTYAMWIKAVK TGSMFWGAICALAYFYMVSSWGGYVFLINLIPLHVLALMVTGRFSHRVYVAYSAVYALGT ILSMQISFVGFQPVQSSEHMAALGVFGLCQIHAFVDYVRSKLSREQFNLLFKTVVLLVGT VIFMALGKITPWTGRFYTLLDPSYAKNNIPIIASVSEHQPTTWSSFYFDLQMLVFLFPAG LYFCFKKLTDANIFIIIYGVTSIYFAGVMVRLMLVLAPVMCILSGIAISATLTTYMKNLD IAKKSEANYPVKNEIATAVVLLTTAFLVTYTFHCTWVTSEAYSSPSIVLAARSGDGGRII FDDFREAYYWLRHNTPEDAKVMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMAS TEDKAYEIMRELDVNYVLVIFGGLTGYSSDDINKFLWMVRIGGSTDRGAHIKEADYYTPQ GEFRIDKEGSQTLLNCLMYKMCYYRFGEVYTEGGKPTGYDRVRNAEIGNKNFELDVLEEA YTTEHWLVRIYKVKDLENRGN-----------------------SMCVQHIPSPLSNARD KVDHIYTGPQDTELAEAMMECDPDGPLMVHTSKLFPTEDATSFHVFGRVISGTLYANQEV KILGENYTLQDEEDSRFGQVCRLWVSEARYKVEVNRVPAGNWVLIEGIDQPIVKTATITE PSGNEEAFVFRPLKFNTSSVIKIAVEPVNPSELPKMLDTARRVAYSAFLMAT-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------PRLMEPYFFVEVQAPADCVSAVYTVLARRRGHVTQDAPVPGSP LYTIKAFIPAIDSFGFETDLRTHTQGQAFCLSVFHHWQIVPGDPLDKSIIIRPLEPQPAT HLAREFMIKTRRR--------------------------------XXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMTE MYFNIDGGYLEGLVRGYKSGILKQTDYLNLVQCETLEDLKLHLQSTDYGNFLANEPSPLA VSTIDDKLKEKLVLEFQHIRNQCVEPFGTFLDYITYSYMIDNIILLITGTLHQRAISELI PKCHPLGSFEQMEAIHIASTPAELYNAVLVDTPLAPYFIDCISEQDLDEMNIEIIRNTLY KAYLEDFYRFCTELGGATANVMCEALAFEADRRAFIITINSFGTELTKDDRAKLYPRCGR LYPDGLAALARADDYEQVRAVAEYYAEYRMMFEGAGTNPGEKTLEDKFFEHEVLLMKNAF MQQFQFGVFYSYVKLKEQECRNIIWIAECVAQRHRAKIDSYIPIFSPRKAIRKISKIPFK VLDAPELQDDFYLNLVDWSSQNVLSVGLGTCVYLWSACTSQVTRLCDLSCDGDSVTSVSW SERGQVVAVGTHKGYVQIWDVTANKRISTLEGHTARVGALAWNADMLSSGSRDRLILQRD VRTPSVVPERRLAGHRQEVCGLKWSPDHQHLASGGNDNKLFVWNMTSVAPVQTYTEHVAA VKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCVDTGSQVCNLAWSKHANELVST HGYSQNQILVWKYPSLVQIAKLTGH----------------------------------- ----------------IVVLVGLYYCLSNQGHRFDIGWFL-ESSPYMWSSIGIGLSISLS VVGAAWGILTTGSSILGGGVKAPRIKTKNLISIIFCEAVAIYGIIMAIVISNNMNYAAGY AMFGAGLTVGLSNLACGICVGIVGSGAALADAQNSTLFVKILIIEIFGSAIGLFGVIVSI LQISHSKMGTKMAASRRLRKELSDDYDESNMLVWQGLIVPVNAPYNKGAFKIKIEFPAEY PFKPPKITFLTKIYHPNIDEKGQVCLPIISPENWKPATKTDQVIQALTALVNDPEPEHPL RGDLAEEYTKDKKKFNKNAEEFTKRYAEKRPSDXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------- -----------------------------------DIIISDFHNHCVKVFDEGTFLFSFG SNGEGNGQFNAPTGVCVDNLGNILVADWGNSRIQVFDSQGSFLSYINLYGPQGLAITKDG NVIVADS-----------MAAGPIAERNQDATVYVGGLDEKVSEAILWELFLQGGPVVNV HMPKDRITQSHQGYGFVEFMGEDDADYAIKIMNMIKLYGKPIRVNKASAHQKNLDVGANI FIGNLDPEVDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAM NGQYLCNRPISISYAFKKDSKGERHGSAAERLLAQQNPLSQADRPHQLFADAPPPPSQST IAPPPPPPTTAAPPTAPPGLPPMSMPPPPMPP------PFMPLPPPAPPGSPPPPGMGGM PPGPPPPGMGPPPGMGPPPGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXMRYVAAYALARLGGNEKPTSEDIIAIIGSVGIEVDMDRLNM VIKHLEGKDLEEVIEEGRKYLANVPSGTTVTAKEEQSQEDSDSDIGLDIF-MSITKIHAR QIFDSRGNPTVEVDLTTDKGLFRAAVPSGASTGIYEALEMRDQEKGLYHGKGVAKAVNNV NGAIASALVVDLKNQGAVDKIMLDLDGTENKAKLGANAILGVSMAVCKAGAAEKGVPLYR HIADLAGNKDLILPVPAFNVINGGSHAGNKLAMQEFMLLPTGASSFTQAMRMGSETYHHL KKVIKDKYGQDACNVGDEGGFAPNIQSNLEGLDLLKVAIEKAGYTGKIKIGMDVAASEFY KKYDLDFKNSASNPAEWLTSDKLADLYMTFIEKYPVVSIEDSFDQDDWEAWAKLTAIQFV GDDLLVTNPKRVKTGIEKKACNALLLKVNQIGSVTESIDACKMSQKNGWGVMVSHRSGET EDTFIADLVVGLSTGQIKTGAPCRSERLAKYNQLLRIEEELGSGAKYAGAKFRNPGPKPV NLATRARPAEPTSFKKYYERGDFPIALEHDTKGNKIAWKVEIEKLDYHHYLPLFFDGLRE TSHPHEFFARQGVHDMLEHGGAKVLPVVPQLIIPIKKALSTRNKQTCCTTLKILQHLVVC EEIVGQALVPYYRQILPVLNIFKNDNVNSGDGIDYSQQKRENVGDLIQETLEAFEKTGGE DAFINIKYMVPTYES--------------------------------------------- NVIKSQLLKDPQVLFAGYKNPHPLEHKIVIRIQTTPDYSPQEAITNAITDLISEVSLLEE RFREAVREKQE--DDHRRKWDSEEYEKLAQERIEAETGIKEPPIKRELLKPREYKVDLDS KLGKSQVITKTTPAAHQGGYYCNVCDCVVKDSINFLDHINGKK----------------- ------------------------------------------------------------ --------------MGCAVSTEDKAAMERTKQIDKILRADGEKASREVKLLLLGAGESGK STIVKQMKIIHEKGYSQEECLQYRPVVYSNTIQSMIAIIRAMGQLKIDFGHPDRADDARQ LFALAGNAEDGE-LSPDLAAVMKRLWKDVGVQECFGRSREYQLNDSAEFYLSALDRISIS GYVPTEQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTA----- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------NVFFRNYEIKSEADRTLIYVTL YISECLKKLQKCSSKNQGLKEMHTLAINRFYLPGESGFPLNAMYAKPANRQEEDVMRGYI QQIRQETGVRVCEKVFDPTTDKPSKWWMCFVKRKFMDKSLSAPGQAGPYNYSYIFKYIII GDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKXKLQIWDTAGQERFRAVT RSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIFLIGNKSDLEAQRDVTYE EAKQFAEENGLMFLECSAKTGENVEDAFLDTAKKIYQNIQDGSLDLNAAESGVQHKPSAP RNPLNTDTPPNKDGCAC----AVCVLNDAGVTGTVTFEQEG-TNLTGEINGLKAGEHGFH VHQFGDNTNGCTSAGPHFNPEGKTHGAPGDEVRHYGDLGNVTADKIDITDKLVSLTGVNS VIGRTMVIHADVDDLGKGGHELSPTTGNAGGRLACGVIGIAKMVNFTIDQIRAIMDRKSN IRNMSVIAHVDHGKSTLTDSLVSKAGIIAGAKAGETRFTDTRKDEQERCITIKSTAISLY YEVAEKDMGRGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQA IAERIKPILFMNKMDLALLTLQLDAESMYQTFQRIIENVNVIIATYEGEDNPMGEIHVDP SKGTVGFGSGLHGWAFTLKQFAEMYCTKFKMTEAKLMKRLWGDQFYDYHRGFTKYILDPI YKIFEFSMTKAETVGLTTKLGIKLSADEKEFDGKVLLKTIMRKWLPAGETLLQMITMHLP SPVTAQKYRMEMLYEGPHDDAAAVAVKNCDSSGPLMMYISKMVPTSDKGRFYAFGRVFSG TVGTGMKARIMGPNYTPIKNIQRTILMMGRYIEPIEDVPCGNICGLVGVDQFLVKTGTLT TFDQAHNMKTMKFSVSPVVRVAVECKNPAELPKLVEGLKRLAKSDPMVQCTIEESGEHII AGAGELHLEICLKDLEEDHACIPIIKSDPVVSYRETVSEPSDRTCLSKSPNKHNRLFMKS RPLTEELASAIDAGTITNRQEPKERARELADKHDWDKTEALKIWCFGPDGQGPNMVTDCT KGVQYLNEIKDSVVAGFQWASKEGVLCEENMRGCRFDIHDVTLHADAIHRGGGQIIPTAR RCLYACMLTACPMMMEPIYLVEIQSPESAVGGIFQTMNKRRGQIIEDNVIPGTPMHLVKA YLPVNESFGFTAELRKNTGGNAFPQCVFDHWQIFIVAETRKRKGLKEGIPALDNYLDKMM LPLSLLRTAVNHPMLVELKNGETYNGHLVNCDNWMNINLREVICTSRDGDRFWRMPECYI RGSTIKYLRIPDEVIDMVKEDAM-KMKGRGDPRQRGRGGPGRGTFGGRGG--GRGGRGGG ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------LSSIEGRVAVEYLDPSPEVQKKKYAFKCHRIKEDGIEKIYPVNAIA FHSAHNTFATGGSDGFVNIWDGFNKKRLCQFHRYPTSIASLAFSHDGSTLAIASSYMYEQ DIPEDNVYIR----------MDFQHRAGGKTGTGGVASASESNRDRRERLRQLALETIDI NKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQANLARRAAKEAKEAPAQPAPE KARVDIKKFVKIGRPGYKVTKQRDPESAQQSLLFQVDYPEIVEAIMPRHRFMSAYEQKVE PPDRKWQYLLFAAEPYETISFKVPSREVDKDAKRFWTHWNKETKQFFLQFAFKHDPK-HT GPP---------MDDEAETYKLWRVRKTIMQLCHDRGYLVTQDELDQTLDQFKAQFGDKP SERHPSRSDLIVLVAHNDDPTDQMFVFFPEEPKVGIKTIKTYCHRMQEENISCAIIIVQT GMTPSAKQSLTDMAPKYILEQFLEAELKVNITEHMLVPEHVLMTPEEKKELLDRYKLKES QLPRIQQGDPVARYFGLKRGQVVKIIRSSETAGRYITYRLVV------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------KREGEKNI LVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLFKKKKGKDLRK SNRAVQKLRREVEKAKRALSSAHQARIEIESLFDGEDFSETLTRARFEELNMDLFRSTIK PVQKVMEDGDLKKDDLHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAV QAGVLSGEEDTGDLVLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQIFSTAADNQPT VTIQVFEGERPMTKDNHQLGKFDLTGIPSAPRGVPQIEVTFEIDVNGILKVGAEDKGTGN KERIVINNDQNRLSPEDIERMINDAEKFADDDKKVKEKVESRNELESYAYSLKNQIGDKE KLGAKLSSEDKETIEKAVNEQIEWLEKNQDAEVEAFKQHKKELEDIVQPIMSKLYQGAPP P---------DVAVEDPELEAIKARVKEMEEEAEKLKEMQSEVEKQMSLEEKMDADNRSI YVGNVDYGATAEELEAHFHGCGSVNRVTILCDKFTGHPKGFAYVEFADKDSVATAMALDE SLFRGRQIKVSAKRTNRPGISTTNRGSRGRSRRPRYTTSYYGYTPRSSRRG-FRPRRSSW YTPY-----------------------------------ILKEEEGRKRVKLLQKQLTEV KRDKEVEVQQRNEMIAHLKDQLQEMKAKTNMEGKYIKKCAEVTVSQTQKKCFLGEKDLRD ETEKLRQNIDEEVRVNAEIESFLRTHKTELEQKVEHWMEKYEKDVEQKQHELDVLKASKA KDLERLQELTKMYAEYEQVVVEDRIEKEKARRKSEQEAEELRAAVRIQSWFRGVMVRRGL GAYSKKKKKKPKIGINGFGRIGRLVLRAALEKVDVVGVNDPFIDLDYMVYMFKYDSTHGR FRGEVKLVVNGKKIAVFNKMKPSEIPWKSVGAYYVVESTGVFTTIEKAKAHQEAGATKVV ISAPSADAPMYVMGVNEDKYSSDETVVSNASCTTNCLAPVAKVINDNFGIEEGLMTTVHA VTATQKTVDGPSGKAWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPVPDV SVVDLTCRLKKPASMDEIKAVIKGPLKGYLGYTEDQVVSSDFIGDTRSSIFDGLAGIALS STFVKLISWYDNECGYSHRVVDLIKYIHK------------------------------- ---------------------------RETVCIVLSDDTVSNDKIRINRCVRNNLRVRLG DVVSIQACPDVKYGKRIHVLPIDDTVEGLTGNLFEVYLKPYFLEAYRPVRKGDIFLVRGG MRAVEFKIIETDPAPYCIVAPDTVIHCEGEPVKREEEEEALNEVGYDDIGGCRKQLAQIK EMVELPLRHPQLFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSK LAGESESNLRKAFEEAEKNSPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQ RSHVIVMAATNRPNSIDGALRRFGRFDREVDIGIPDATGRLEIMRIHTKNMKLADDVDLE QVAAETHGHVGADLAALCSEAALQQIREKMELIDLEDETIDAEVLASLAVTQEDFRWALS KSNPSALRETAVEVPNVSWEDIGGLENVKKELQELVQYPVEHPDKFLKFGMTPSKGVLFY GPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFD ELDSIAKSRGGSAGDGGGAADRVINQLLTEMDGMSNKKNVFIIGATNRPDIIDPAILRPG RLDQLIYIPLPDDKSRISILKANLRKSPVSKDIDLDFLAKNTHGFSGADLTEICQRACKL AIRQSIEAEIRKERERAANPDETDPVPEITRDHFEESMKFARRSVTDNDIRKYEMFAQTL QQSRGFGS-------------STANHNPMKDIEVASAPDDSVSSLSFSPGTLPSTYLIAG SWDNNVRCWEVQQNGTTIPKAQQTHTGPVLDCCWSDDGTKVFTASCDKTAKMWDLSSNQA VQVAQHDAPIKTIHWVKAPNYTCIMTGSWDKTLKFWDTRTPNPMMTVNLPERCYCADVQY PMAVVGTAGRGLIIYQLENQPREFKRIDSPLKYQHRCVSIFPDKKTSGPVGFALGSIEGR VAIQYVNPVNPKDNFTFKCHRPAVQDIFAVNGIAFHPVHGTLSTVGSDGRFSFWDKDART KLKTSEQLDQPISTCTFNAQGNIFAYASSYDWSKGHEGFDPQKMKPHIFLRSCYDELKPT GAKMSSPSPGKRRMDTDVVKLIESKHEVTILGGLNEFIVKFFGPKDTAYEGGVWKVRVDL PEKYPFKSPSIGFMNRIFHPNIDEVSGTVCLDVINQAWTALYDLSNIFESFLPQLLTYPN PIDPLNGDAAAMYLHKPEDYKKKVAEYVKKYATEEALREQESSLSDFSEDEAQDMEL--- -DVLTTLKILIIGESGVGKSSLLLRFTDDTFDPEQAATIGVDFKVKTLAVDGNKAKLAIW DTAGQERFRTLTPSYYRGAQGVILVYDVCSKHSFNKLDAWLNELETFSTKHDIVKMLVGN KIDKDKREVSRDEGLKFARKHHMLFIEASAKTKEGVQCAFEELVEKIIQTPGLWETDGIT LTSVIWSVINGSFCSFKVKTKPQMFCRNEFNVTGLCNRSSCPLANSQYATVREEKGVIYL YMKTIERAAFPRNLWEKVKLSKNFEKALQQIDEHLLYWPRFLRNKCKQRYTRITQYLIRM RKLMLKRSKKLVPLSRKVERRETRREEKALVAAQLDNAIEKELLERLKKGTYGDIYNFPQ HAFDKALEEEEVSEQEQSEEEIEYVGEEEFEESDVSDVELVQTRFQAEPRMKQFTIYRWN PDKAEDKPHMQTYEVDLNTCGPMVLDALIKIKNEMDPTLTFRRSCREGICGSCSMNIAGT NTLACLCKVDANTSKATKIYPLPHMYVVKDLVPDMNNFYAQYRIIEPYLKKTDLKEEDVG KKSYLQSVEDRAKLDGLYECILCACCSTSCPSYWWNSDKYLGPAVLMQAYRWIIDSRDDF PNDRLSKLQDQWSAYRCHTIMNCTKTCPKGLNPGLAIAELKKMML--------------- ------------------------------------------------------------ -----------PV--------------------------------------APATIPEQP PNQILFLTNLPEETTEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENEIQSAAAKDALQ GFKITPTNAMKISFAKK-------------------------NFPAHIFPSLVGRPIIRS SVKVGDIEIKDLMVGDEASQLRSMLEVNYPMENGIVRNWEDMMHLYDYTFGPQKMNINPH ECKMLLTEPPMNPTKNREKMVEVMFEQYQFDGLYIAIQAVLVLYAQGLLTGVVVDSGDGV THICPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRIMKEKLCYV GYDIEQEQKLALETTVLVESYTLPDGRVIKVGGERFEAPEALFQPHLIDVDGVGVAELLF NTIQAADMDTRPEFYKHIVLSGGSTMYPGLPSRLEREIKQLYLERILKGDTEKLSKFKIR IEDPPRRKHMVFLGGAVLADIMKDKETFWMTKQEYQEKGLNVLEKLGVSMADTTGKTITC KAAVAWEAKKPLKIEDIQVAPPQAGEVRIKILATGVCHTDAYTLDGFDSEGAFPVVLGHE GGGIVESVGEGVTSVQPGDHVIPLYIPQCGDCKFCKSPKTNLCSKIRGTQGKGVMPDGTS RFSCKGQTLYHFMGTSTFSEYTVVAEISVSKVTEKAPLESVCLLGCGISTGYGAALNTAK VEKDSQCAVWGLGAVGLAVLMGCKKAGASRIIGIDINPDKFEIAKQFGATECINPKDYDK PIQQVLVDMTDGGLDYTFECIGNVATMRAALEACHKGWGVSVIVGVAAAGKEISTRPFQL VTGRTWKGTAFGGWKSRDSVPKLVEEYLEGHCKVDEFITHTMKLDKINEAFDLMHEGKSM DAYDVIANQPVVIDNGSGVIKAGFAGDQVPKYHFPNFIGRPKHVRVMAGALEGDIFLGPK AEEHRGLLSIRYPMEHGIVTDWNDMERIWAYIYSKDQLQTFAEEHPVLLTEAPLNPRRNR EKAAEIFFETFNIPALFISMQAVLSLYATGRTTGVVLDAGDGVTHAVPIYEGFAMPHSIM RVDVAGRDVTRYLQLLLRKEGQNFHTSAELEIVKTIKERACYLSINPQKEESMETEKSTY TLPDGSILEIGPARFRAPELLFRPDLIGEECEGIHEVLAYSIQKSDMDLRRVLFSNIVLS GGSTLFKGFGDRLLSELKKLAPKDIKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKR EYDEEGVRAVHRKTFDPNKISKVVVHPLVLLSCVDHFNRMGKVSNMKRVVGVLLGSNRQG VLDVSNSFAVPFDEDEKDKSVWFLDHDYLETMYGMFKKVNARERIVGWYHTGPKLHQNDI KVNELVRRYCPNSVLVIVDAKPKDLGLPTEAYIAVEEVHDDGTPTSKTFEHIPSEIGAEE AEEVGVEHLLRDIKDTTVGSLSQRITNQLMGLRGLNGHIQDIHSYLEKVVSGNLPINHQI IYQLQDIFNLLPDVNLHTFVKAVYVKTNDQMLAVYLASLIRSVIALHNLISNKVQNRDAE KNEGKVKK---------------------------------------------------- ------------------------------------------------------------ -----------------------------------------IQACCALTGEGLYQGLEWI SSHLRR-----RRVILNDPSQLPNDYSTTPGGTIFSTTPGGTRIIYDRAFLMKCKDSPLA KTPPTNLPTIPGVTSPPPPGKRKEIYKYEAPWTVYSMNWSIRPDKRFRLALGSFVEEYNN KVQIICLDEETSEFTSRSSFDHPYPTTKIMWIPDNKGVFPDLLATSGDYLRVWRATRLEC LLNNNKNSDFCAPLTSFDWNEVDPNLLGTSSIDTTCTIWGLETGQVLGLVSGHVKTQLIA HDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHQPLLRLAWNKQ DPNYLATMAMDAMEVIILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAGDDHQAL IWDIQQMPRAIDDPILAYTASGEINQIQWSSTQPDWIAICYNNCLEILRVRHFSASNKVA VMGASGGIGQPLSLLMKQNPIISHLALYDIVHTPGVAADLSHISTKAKVTGHIGPGQLKE CLQGCDLVVIPAGVPRKPGMTRDDLFNTNASIVRDLADACARHCPKAILAIISNPVNSTV PIASEIFKLRGVYDPKRIFGVTTLDIVRANTFIAESKDLKVSKVNCPVIGGHSGVTIVPI ISQCNPPVSFPQDEREKLTSRIQNAGTEVVEAKAGAGSATLSMAFAGAKFADGVLEALNG EQGVVQCAFIASDETEASYFSTPVLFGRNGLEKNLGMGKLIEYEVNLVDKAMPELKGNIQ KGIDFVANNIDRGKDFNIKTRIITDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFAS TLSHLRRLNSPVGRDGKLARPRQLHNTQWGMICPAETPEGGAVGLVKNLALMAYISVGSQ PSPILEFLEEWSMENLE------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------EVLYNGHTGRKLNAQVFLGPTYYQRLKHMVDDKIHSRARGPVQILNRQPMEG RSRDGGLRFGEMERDCQIAHGAAQFLRERLFESSDAYRVHVCNICGLIAIANLRNNTFEC RGCKNKTQISQVLLPYACKLLFQELMSMSIAPRMMVICVEPVGGFSFGNCSRNAFLEQGA KPPRALKTGTTICGIIFKDGVVLGADTRATEDTIVADKNCAKIHFISDNIYCCGAGTAAD TEMTTQIISSQLELHRLNTGRVPRVCTANRMLKQMLFRYQGHISAALVLGGVDSNGPHLY SVYPHGSTDKLPYVTMGSGSLAAMAVFEDGFKPDMERGEACQLVRNAVAAGIFNDLGSGS NVDVCVITKKVEYIRPFDEANQKGQRQGNYLYKRGTTAVLTEKVKKLEFDVVMSKVTFKI TLTSDPKLPYKVLSVPEQTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPAQSAGNVFL KHGSELRLIPRDRVGHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGLLTILKKMKQKEKEVRLL MLGLDNAGKTTILKKFNGEDIDTISPTLGFNIKTLEHRGFKLNVWDVGGQKSLRSYWRNY FESTDGLIWVVDSADRRRLEDCKQEMDALLLEERLAGATLLVFANKQDLPGALPAEQIKD ALDLDNIKSHHWLIQDCSAVTGENLLEGIDWVVNDIASRIFTMDHSKKRICYYYDGDIGN YYYGQGHPMKPHRMRMTHNLLLNYGLYRKMEIYRPHKATQEEMTKFHSDDYIKFLRSIRP DNMSEYNKQMQRFNVGEDCPVFDGMYEFCQLSAGGSVAGAVKLNKQAADIAINW------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------DTSAY ECNICLDTARDAVVSMCGHLFCWPCLHQWLETRPNRQVCPVCKAGISKDKVIPLYGRNST TPQDPREKLPPRPQGQRAEPENNGGFPSFGFGFQMSFGIGAFPFGFFASTFNLADGR--- ---------EEQFLSKIFLWIAVLFIFWLMIA-----HKQEQAHDDSIWSCAWAKSEKDG IENIITGSVDDTVKVWKWIDLELRHTLEGHQLGVVSVDINHNGTLAVSSSLDSHIRLWDL ETGKQVKSIDAGPVDAWTVCFSPDSRFLTSGSHTGKVNLFGVESGKKESALDTRGKFTLS VTYSPDGKYIACGAIDGIINIFDMGT---------------------------------- ----------TLSGHGSWVLNVAFSPDNKFFVSSSSDKTVKIWDAGTRQCVHTFYDHLDQ VWCARYNGTGTKIVSVSDDRAVHVYECPILSEDDYDDEAVKFFERTDIDGWDVRRVLTNM QGEDLIPEPKIIIAALHAMRRLNDYALAVRYLEALQDKCANRVGEIWPYIMQEIQPTLTE LGISSPKEMGYDKPELACQATYEM------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------SHSSQTGHSVHLRGLPFAANEQDILEFFRPLNPVNVVIH YQGGRATGECDVDFATHDEAKLGMKKDRTMMQHRYIELF--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TNVDLRDIKLIRKLGGTVDDTELV DGLVFNQRTAGSGGPSKIEKAKIGLIQFCISPPKTDMENQVIVSDYTQMDRVLREERQYI LNIVKQIKKAGCNVLLIQKSILRDAVNDLALHFLAKMKMMVVKDIEREDVDFICRSLNCK PIASLDHFQPEMMGSAE-VEEVQTGASKVVKVTGIVNPGKTVSVIVRGSNKLVLEEADRS IHDALCVIRCLVKKRALIAGGGAPEIEVALRLAEYSNTLSGMEQYC-------------- ------------------------------------------------------------ ---------------MILLEINNRIIEETLTLKFTNALAGNKPDLVDVTVADFDGVLYHV SNPDGDKSKIRVSISLKFYKDLQEHGADELITREYGPFLTSPEDGYNVSLLFDDNIPPNH EEVIKKAGLLKRNCFASVFEKYFEFQQKHKRAIIHYREDETMYV---------------- -----------------------------------------TDAMTGDNIGYITFVLFPR HEARENTIDLIHTLRDYLHYHIKCSKAYIHSRMRAKTSDFLKVLNRARPEPKNVEKKTIM LMFCPICANVLVVEEGPNCYRFACNTCPYIHNISRKISNRKYPKLKEVDDVLGGAAAWEN VDSTAETCPKCSHARAFFMQIQTRSADEPMTTFYKCCSMSCGHRWRKTKFGPLKDEDRIF TNLYGRHDWRLKGAMQRGDWYKTKEIIQKGYEWIQGEIKASGLRGRGGAGFPTGLKWSFM NKPDDGRPKYLVVNADEGEPGTCKDRDIMRHDPHKLVEGCLIAGSGMGARAAYIYIRGEF YNEASNMQIAINEAYQAGFLGKNACGSGFDFDVYMHRGAGAYICGEETSLIESMEGKQGK PRLKPPFPADVGVFGCPTTVNNVESIAVAPEICRRGAEWFASFGRPRNTSVLMDFDDLVQ NQTGLGTAALIVMNKSSDIVRCISRLADFYKHESCGQCTPCREGCNWMAKIMHRFVIGKA KADEIDMLYEMSKQIEGHTICALGDGAAWPVQGLIRHFRPELEARMKAYAESQFTQEQVD DMNQQLNQTRSQRVRAAMFPETLEEGIQIPSTQMNPDQPTAVQRLAEPSQMLKHAVVNLI NYQDDADLATRAIPELTKLLNDEDQVVVSQAAMMVHQLSKKEASRHAIMNSPQMVAALVR AMSNTTDVETTRCAAGTLHNLSHHRQGLLAIFKSGGIPALVKLLSNPVESVLFYAITTLH NLLLHQEGSKMAVRLAGGLQKMVALLQRNNVKFLAITTDCLQILAYGNQESKLIILASGG PGELVRIMRSYTYEKLLWTTSRVIKVLSVCSSSKPAIVEAGGMQALAMHLGHQSQRLVQN CLWTLRNLSDAATRNDALEGLLQMLVQLLASNDINIVTCAAGILSNLTCNNQRNKVTVCQ VGGIEALVRTILQAGDREDITEPAVCALRHLTSRHPECEMAQNAVRLHYGLPVLVKLLHP PSRWPLIKAVVGLIRNLALCPANHAPLREHGALPRIVQLLIRAHQDTQRSQSAYVDGVRM EEIVEGTVGALHILGREAHNRAVIRGLNCIPLFVQLLYSPVENIQRVAAGVLCELAADKE GAEIIEQEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRNE PMSSDLQWMIIRNNSSFLMKGSSFSKEPNNLKNSNSYRYNGLVHRKTVGVEVLDDGKGVA LVSKTGTSKPNHLFTRTDLKRGHKRSLNTIRKVLRNNKYRKDLVNAAVLRAGLLLKSQKP VVPKKTQDEPYYCSQQINIPPELPDILKQFTKSAIRTQPKDVLSWSAAYFRAMANGETPP VKERLEMPVATQKTDTGLTPGLLRVLNKQLGPKKTVPLQLIEDKWVDLALPKEQFDELVR IGSFGGDVEWLKFFAIGSSALGENVTDAMKTVCEILTADPDGGPARIPFPQFQELYKYLA QIDGEIPQEHIEEVISYLSVYVDKQDGMVQPRNFLSPDCPKLSGKIDGQSREQLMEQVKA QMAIVNAQELLQKMSDKCFKKCVTKPGTSLDNSEQKCVAMCMDRYMDAWNLVSKTYSNRL QKERNK-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------QHCKADFCWVCLGPWEPHGSSWYNCNRF DEDEAKKARDAQERSRAALQRYLFYCNRYMNHMQSLKFEHKLYTSIKLKMEEMQQHNMSW IEVQFLKKAVDVLCQCRQTLMYTYVFAFYLKKNNQSIIFEDNQKDLENATEQLSEYLERD ITSDMLVDIKQKVQDKYRYCESRRKVLLDHVHEGYERELWDYQD---------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------GGLSPEIHNLEDIRKLDRFKEPPAFGPMCDLLWSDPLEDFGNE KTNEHFTHNSVRGCSYFYSYTACCDFLQSNNLLSIIRAHEAQDAGYRMYRKSTTTGFPSL ITIFSAPNYLDVYNNKAAILKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVT EMLVNVLNICSDDELEQEGDESFE----ARKEVIRNKIRAIGKMARVFTVLREESESVLQ LKGLTPNGLLPIGALSGGQETLRNALSGFSPNHKISGFEEAKYLDKMNERMPP------- ------GRGGRGGG-----RGGRGGGRGGRGGMRGGRSVVVEPHRHQGVFIARGKEDALV TKNMVPGDSVYGEKRITVEEGNKIEYRAWNPFRSKLAAAILGGVDKIHITPGSKVLYLGA ASGTTVSHVSDIVGPEGLVYAVEFSHRSGRDLINVAKKRTNIIPIIEDARHPHKYRMLVG MVDTVFADVAQPDQARIVALNAHNFLKNAGHIVISIKANCIDSTAKPEAVFAGEVNKLKQ EKIKPQEQLTLEPYERDHAVVVGQYRPPPK------------------------------ ------------------------------------------------------------ -------KDLQMVNIALRVLSRPDSSKLPTLYRQLGQDYDERVLPSICNEVLKSVVAKFN ASQLITQRQAVSLMVRRDLTERAKDFNIILDDVAITELTFGREYTAAVEAKQVAQQEAQR AQFFVERAKQERQQKIVQAEGEAKAAEMMGLSMSLNPGFLKLRKIRAAQNIARTIAQSQN KVYLNASTLMLNLSDKEFEDNI-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------QACMDGF RVVTLNEVVKQVDVVITCTGNKNVVIREHMDRMKNGCIVCNMGHSNTEIDVNCIRTAELT WERVRSQVDHVIWPDGKRIILLAEGRLVNLSCSSIPSFVVSITAATQALALIELFNAPNG RYKQDVYLLPKKMDEYVASLHLPTFDAHLTELSEEQAKYLGLNKAGPFKPNYYRYPDPDA IKMFVGQVPRSMDENELRKMFEDFGPIYQLNVLRDKVTGQSKGCCFITFFSRKAALDAQN ELHNIKTMPGMQHPVQMKPADSEKRNVEERKLFIGMLSKKCTENDVRMMFAPFGTIEECT VLREQSGQSKGCAFITYSNKQCATNAIKQMHHSQTMEGCRSPLVAKFADTQKEKEMKKLQ QVNNTIQMQFVAGALGGASATYATHWLDTLKVKMQSFPQLYMSATGCLRQSLKEEGLCGL YKGATPSIRAAVVFSCYGLCQDFVEVTGVLSGIILCPIELLKCRLQALMKNIVYSEGILG MFRGLTTTWAKMIPCSFIYFGSYEQSKTLCREFQE-KDILSPVVFMCGGVAGIC-SAVVF PLDVLKTRVQVREEGLTPLTSGLKPFLLRTCLFSAIQLVVYEQIKK-------------- ------------------------------------------------------------ -------KMQKERLMNEFTSALNNFQSAQRKAADREKASVENVDLQLIQEREQSIRKLEA DIMDVNQIFKDLGMLVHEQGDMIDSIEANVENVHVEQGTQQLSKAKDYQSKARRKK---- -------------------MVNVMKGVMVECDPAMKQFLLHLDENNALGKKFVIQDLDDT HIFIASDIIPILQDRIDELMDKLSFPIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------FIFNPRTGHLFLKIIHTSV WAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKG SELQLPFQACLKVEKFGDLILKATEPQMVLFNLYDDWLKTISSYTAFSRLILILRALHVN NDRTKIVLKPDKTTVTEPHHIWPTLSDEEWIKVEVQIKDLILADYGKKNNVNVASLTQSE IRDIILGMEISAPSAQRQQIAEIEKQTKEQSQLTATTTRTVNKHGDEIITSTTSNYETST FSSKTEWRVRAISATNLHLRTNHIYVSSDDIKETGYTYILPKNVLKKFIIISDLRAQIS- ------------------------------------------------------------ ------------------------------------------------------------ ------------VQMLLSDRFLGFFMVPSHSSWNYNFMGVRHDPNMKYELQLANPKEFYH EVHRPSHFLNFSSLEEGADREDLYSCYTATRPNLMLTKNTKVICQGFTGKQGTFHSAQAI EYGTNIVGGISPKKGGQMHLGLPVFNNVQEAKDATGADASVIYVPPSFAAKAIIEAIDAE IGLVVVITEGIPQQDMVRVKHRLLRQSKTKLLGPNCPGIIKPGECKIGIMPGHIHKKGRV GIVSRSGTLTYEAVHQTTQVGLGQTLCVGIGGDPFNGTNFIDCLEVFLNDPDTHGIVLIG EIGGQAEERAAEYLKKHNGPNAKPVASFIAGLTAPPGRRMGHAGAIISGGKGGAEEKIQS LKDAGVHVTMSPAQMGTTLYKAFEDQG--------------------------------- -----------------------------SNVPWAFMQGEIATILGFQRFVEIGRVAYIA FGPDEGKLVAIVDVIDQNRALVDGPCSGVSRKQLSFKQLHLTKFVLFLHGARTGTVQKAW EKENISEKWAETTWAKKIEQRKKRAGLCDFDRFKLMKAKQARNKLVTIQFGRLRKAAKKT CPLLLRVFCNTIRHNPVNEYSRGNTPTNELQIYTWMDATLKELTSLVKEVNTDARRKGTF FDFAIVYPEVRQPVYRIKEIGSTCAGRKGTDDNVTLISKRFKIGDYIDIAISPP------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------EMKLRLDNIVI QQGRLVDNNTNKEVLNMIRHGANHVFASKDSEITDEDIDIILERGEKKTAEMRKKMETLG ESSLRSFSLDTNESSVYQFEGEDYREKQKLGGIGHWIEPPKRERKANYAVDAYFREALRV SEPKAPKAPRPPKQPNVQDFQFFPPRLFELLDREIYCYRKSIGYRVPKNPDLGSDAERAR KEEQRKIDEAEILSEEEMTEKEDLLSGFTSWSKRDFNQFIKANEKFGRDDIDSICREVEG KTPEEVMEYSSVFWERCNELQDIERIMAQIERGEAKIQRRISIKKALDAKMARYRAPFHQ LRIQYGTNKGKNYTEEEDRFLCCMLHKLGFDKENVYDELRTMVRQAPQFRFDWFIKSRTA MELQRRCNTLITLIERENMELEEKEKAERKK----------------------ETLDEES GFRTITEYKVNDEGKKVRVVKTYKIETRKVSKSIARRKAWRKFGAAVGDPPGPNPSNTIE DVFMVFVHNKES-EDDPLN-XKVTCRICKGDHWTTRCPYKDTLQPLQETASKPGKYVPPS LREGANRRGESMNSDETATVRVTNLSEDTRESDLQELFRPFGTISRIYLAKDKITGQSKG FAFINFHHREDGARAIAGVSGFGYDHLILNVEWAKPS----------------------- --------------------------------------WDTAGQERFKSVTKGYYRSAAG ALLVYDIARRDTYNALADWMADVRTVASPNIAIILVGNKKDLEAEREVTFIEASRFAQEN EVLFLETSALTGDNVEETFLKCTRSILTDIESGELDPDGIGTGIQCGDTSVRLLSNRRTN C--LIKPASTEELHSSQWPLLLKNIEKLNIRTAHYTPIPAGCSPLKRPIDEYVKTGFLNL DKPSNPSSHEVVAWIKRILRVQKTGHSGTLDPKVTGCLIVCIERATRLVKSQQGAGKEYV CIFRLHSAVEDECKLARAIETLTGALFQRPPLISAVKRQLRIRTIYESKLLEYDKERNMG ILWVSCEAGTYIRTLCVHLGLMLGVGGQMQELRRVRSGIQSEKDNLVTMHDVMDAQWVYD HHKDETYLRRVIKPLEALLTTHKRIMMKDSAVNAMCYGAKIMLPGVLRYDDGIEMNEEIV MITTKGEAIALGIALMTTAVIATCDHGIVAKLKRVIMERDAYPRKWGLGPKASMKKKMIK EGLLDKYGKANEQTPKDWTSSYADYNIKRKMKDSQPSSGKKEKKKKKKMAECDWDRKKQP KSGQLRSQQALSAAQRSGVEIDTSKKYSAGQNKQHSAHKNTAKLDRETEELHHEKIGLDV GKLIMQGRQAKQMNQKDLATKINEKQQVINDYEGGRAIPNQQVLSKLERVLEMKLRGKDK GQ-----MLKPKALTQVLSQANTGGVQSTLLLNSEGALLAFSGYGDKDARVTAAIASNIW AAYDKNGRAAFNEDNLHYILMDCQEGKVAITRVANLLLCIYAKESVGFGMLKAKAEALAE YLEEPLKEVAAS--------------------------------------------MRTN LPVFKVKESSVRRRYSDFEWLKNELERDSKIVVPQLPGKALKRQLPFRSDDGIFDEEFVE ERRKGLEAFVNKVAGHPLAQNEKCLHMFLQEPIIDKNYVPGKVRTT-------------- ----------------------------------EKDMQEVNSKRMPGRIHTYYQVLIDG RDIEHITAQRDAVTYLGKEKRIKIYAIPGLDYIAHEDVLPYSTTERKPIEHELFDKFLMR DPPFIARDSLRAWILQNHPWLELSDVHR-------------------------------- ------------------------------------------------------------ -------------------------------MATAKGANTYNRQNWEDSDFPILCQTCLG DNPYIRMTKEKYGKECKICARPFCVFRWCPGGRMRFKKTEVCQTCSKLKNICQTCLLDLE YGLPVQVRDAALKIQDEMPKSDVNKEYYTQNMEGALANNDGTNPLGAVGKAQTPSDMLLK LARTTPYYKRNRPHICSFWVKGECKRGEECPYRHEKPTDPDDPLADQNIKDRFYGTNDPV AEKLMKRYSAMPKLEPPED----------------------------------------- ----KDNKTLGDLGITSSTARAQDPATVGLAYREFENLEVTPYSCPPELPDVMKPQADSS SHPQE----------------------------------------HPQPIRYQNSPSGMA WDREAFLPDWIMDTWHPLEKARYPEYFERREQRKKEYIE----------MEDYVKIEKIG EGTYGVVYKGRNKKTNKYVALKKIRLESEEEGVPSTAIREISLLKELAHPNIVLLEDVLM QENKLYLVFEFLSMDLKKYMDTIPSGQYMDKMLVKSYCYQILQGILFCHQRRVLHRDMKP QNLLIDNKGVIKLADFGLARAFGIPVRVYTHEVVTLWYRAPEVLLGCQRYSTPVDVWSVG CIFAEMVTKRPLFHGDSEIDQLFRIFRTLTTPTEEVWPGVTEMPDFKPSFPNWKTNTLAN SVEEAGLDILKKMLIYDPAVRISAKAALQHEYFASRLFGTIGKVGLGLAVIGGVVNTALY NVDGGHRAVIFDRFAGIREKVVGEGTHFIIPWVQRPIIFDIRTRPRNIPTVTGSKDLQNV HITLRILFRPIPDKLPEIFQTLGVDYDDRVLPSITNEVLKAVVAQFDASELITQRELVSQ KVNEELTNRGQHFGLILDDIALTHLTFGKEFTEAVELKQVAQQDAERARFIVEKAEQQKQ AAIATAEGDSLAAEMLAKAFGDAGDGLVELRKLEAAEDIAYQLSRSPNVVYLPQGQQTLL SLPMKTIKANQLVTIPDGVEVLVNNRKVTVKGPRGILRRDFRHMSVDIKKVKSNELLVEK WYGIKKELAAVRTVCSHIENMFKGVIKGYKYKMRSVYAHFPINIVLTENGGMVEIRNFLG EKFTRRVRMLKGVTCASSTAQKDELILQGNDIELVSRSAALIQQSTTVKRKDIRKFLDGI YVSEKTTVIE-------------------------------------------------- ------------------------------------------------------------ --------------------------------------LNDSAEYYLSALDRISMSGYIP TEQDVLRTRVKTTGIVETHFTFKDLKFKMFDVGGQRSERKKWIHCFEGVTAIIFIVAMSE YDLSLAEDQEMNRMMESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICFPE FNGSNTYEEAAAYIQMQFNKRKDTKEIYSHFTCATDTNNVQFVFDAVTDVIIKTNLKDCG LFKKFAAMKRLISLKDTRIKKKDRETKKRKKADPQNMKIRELPQASSALFFQYNTQLGPP YHVLVDTNFINFSIKNKLDIVRSMMDCLFAKCIPYITDCVMAEIEKLGSKYRIALRIAKD PRFEKLPCLHKGTYADDCLVQRVTQHKCYIVATCDKDLKRRIRKIPGVPIMYVVQ----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GHTNEVNAIKWDPQGSLLASCSDDMTLKIWNMRQDTCVHNLEAHS KEIYTIKWSPTGPGTDNPNAPLILASASFDSTVRLWDVDRGACIHTLT-HQDPVYSVAFS PDGRYLASGSFDKCVHIWNVQSGALVQSYRGTG--------------------------- ---SNNDLASYFECPVCFDYALPPIMQCQSGHIVCSSCRPKLTGCPTCRGPLGNIRNLAM EKVAATVMFPCKYSQSGCPMTLLHTDKTDHEETCEFRPYCCPCPGASCKWQGSLEQVMPH LMHQHKSITTLQGEDIVFLA---------------------------------------- ------------------------------------------------------------ ---------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XX-MELLSDQGFRIDGRRPHELRRIQCKLGVFGQADGSAYIEQGNTKVLAAVYGPHETR- ERSKLDKVLINCQYSMATFSTGERKRRPRGDRKSQEMTQHLQQTFDAAIMTHLYPRSQID IYVEVLQSDGGNYCASVNAATLALIDAGIPMK---------------------------- -----------------------------------------------------GNYYFAV VGHHDNPVFEMEYFPANKANEPKKDDHRHLNQFIAHAALDLVDEQMWMTNSMYLKIVDKF NEWFVSAWVTAGRMRFLMLHDVKNEDNIKNFFTDMYEIYIKHAMNPFYEVNTPIKSAAFE RKAQFYGRKYLPTQVRFAHTDIKVPDFDFYRKDSVKDSRRAFTYMLALGGGFAGAYVGKG VVVDFIASMSASADVLALAQIEVKMDEVPEGKSVTFKWRGKPLFIKHRTTEEIERERAVD LSTLRDPQHDDDRVKAPEWLVLLGVCTHLGCVPIADQGQYGGYYCPCHGSHYDASGRIRK GPAPLNLDIPPWEIGGDKVIV--MSRQTSRSADPRKVSGELFTLTYGALVAQLLKDYESD EEVNKQLDKMGYNIGVRLIEDFLARANVGRCHDFRETADVIAKVGFKMFLGVAPVVTNWS PAGDEFSLIMETNPLTDFVELPEGHNHLQFSNILCGALRGALEMVQMDVDVRFVQDQLKG DNITEIRLKFIKRLEDAVPAGED------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVY EMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNAVN DIKNHKWFSTTDWIAIYQKKVEAPFIPKCKGPGDTSNFDDYEEEPLRISSTEKCSKE--- -MLADTLLIVFISICTALLGEGLTWLLVYRTETYIKLKAEVEKQSKKLEKQKESGAEASD RSHKKKIERQEEKLKNNNRDLSLVKMKSMFAIGFAFTALLSMFNSIFDGRIVAKLPFVPI SWIQGISHRNLIGEDYTDCSFIFLYILCTMSIRQNIQKLLGFAPSRAASKQGGGLFNT-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------LTGHTGSVLCLQYDENIIISGSSDSTVRVWSLKTGEMLNTL IHHCEAVLHLRFSDGIMVTCSKDRSIAVWDMQSPTDINLRRVLVGHRAAVNVVDFDDKYI VSASGDRTIKVWSTSSCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACL RVLEGHEELVRCIRFDGKRIVSGAYDGKIRVWDLTAAMDPRAPAGTLCLRTL-------- -------------------------MAKQYDLLFQLLLIGDSGVGKTCMIYRFAEDDFPE GRMTTLGIDFKVKRVFLEGKRVKIQLWDTD-----ETITKHYYRRAQGVALVYDITNDKS FRNVQKWFNYIKENSSEDTELILLANKTDMEEMRRITCQQGHQLAKELDVPF-------- ----------------------AEGETSADRNVEIWKIKKLIKSLEAARGNGTSMISLII PPKDQISRVAKMLADEFGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVIYCGT IVTDEGKEKKVNIDFEPFRPINTSLYLCDNKFHTEALTALLADDNKFGFIVMDGNGSLFG TLSGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAEVAVTLYITNDKP NVAGLVLAGSADFKTELSQSDMFDPRLQAKVLKVVDVSYGGENGFNQAIELASEALSNVK FIQEKKLIGKYFDEISQDTGKYCFGVDDTLRALQMGAVEILIVWENLDIQRYVLRNHQTD EDKTLFLKPEQEKDKTHFTDKDTGVELELQDSQPLLEWFANNYKSFGATLEIITDRSQEG AQFVKGFGGIGGILRYQVDFQSLEVVDDLADDFDLDDY---------------------- ----------LYIMDARPSVNALANKAKGGGYENEDSYQNMEINFLDIHNIHVMRESLRK LKDVCFPTIDDAHWLSNVESTHWLEHIKYILGGAVKIADKVESNKMSVLCHCSDGWDRTA QLNALAMLMLDPYYRTIRGFEVLIEKEWLSFGHKFAQRIGHGEDKHSDADRSPVFLQFID CVWQMTSQFPNAFEFNEHFLITILDHLYSCLFGTFLFNCEQQRNKEDVRHKTVSLWSYIN CQLEEFMNPLYQHVIFPVASLRRLELWRGYYLRWNPRMKPQEPVHLRNRELLVLKSQLQK RLDELQRELDAKNSPFRAYIPHVPFDLAQCESAFPRPKTVPEEKNFTDALLKRNSDLTPS APEQSSVLNLVTKISGVLDNLIISPGAFDAAQLEEVRQVGSHKKGTMLTGHNVADLVVIL KTLPTLEAVNALGNKVQEELKASDPNEVVTMLTNDSGFEVSSAEATVKVLITTIPPNLKK LDPELHLDQKLMQGHLAAIRHARWFEENAFHSSIKVLIRLLRDLKSRFEGFEPLTPWIID LLAHYSIMNNPSRQPLAINIAFRRSLQLLAAGFFLPGSAGITDPCEQGNIRIHTVMTLEQ QDQVCFTAQTLLRVLGHGGYKQILGLEGN---------------------------VVRL IEQYLKENNLLRTLSLLQEESGISLNTVDSVDSFVSDINNGHWDTVLQAIQSLKLPDQKL IDLYEQVVLELIELRELGAARSLLRQTDPMIMMKQNQAERYVHLENMLARSYFDPREAYS EGQTKERRRAAIAQALSGEVNVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAV REQEDEKYPTQLSKTIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKVRKDLK YQAQDNFMMMDDAVLCLCFSRDSEMLATGGQDGKIKVWKIQTGQCLRRFERAHSKGVTCC NFSKDSSQLLSASFDQTIRIHGLKSGKTLKEFRGHTSFVNDVVFTPDGHHILSASSDGTI KVWNIKSTECQNTFKSLGGSAGADITVHSVHPLPRNVEQFVVCNRSNTVVIMNMQGQIVR SFSSGKREGGDFVCASVSPRGEWIYCTGEDMVLYCFSITTGKLERTITVHEKDVIGIVHH PHQNLISTYSEDGLLKLWKPMAKAVQLPSVAMQFATPKFNTFVRYAKVELTPPSQMPQVQ EGFQKLIFARTGAWKNLTVKQATLVAVEIGCWFFIGECIGKGSIIGYQIPGAYFNELH-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------LRVYGQYLNLDKDHNGMLSKE ELARYGTGTLTDVFLDRVFQECLTYDGEMDYKTYLDFVLALENRKEPQALQYLFRILDVQ NKGFLNVFDLNYFFRAIQEQMKLH-----------------VKPQDALQILLQDLVNSGQ GDTVVSILIDLNGFWTYENRE--------FEVAPRYTNLAYIGEGAYGMVVSANDHVTNT KVAIKKISPFEHQTYCQRTLREIKILTRFKHENIIDIRDIIRSPTLEDMKDVYIVQCLME TDMYKLLKTQQLSNDHVCYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFG LARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDVWSVGCILVEMLSNRPIFP GKHYLDQLNHILGVLGSPSQDDLSCIINDKARGYLQSLPFKPKVPWKQLADPKALDLLDR MLTFNPGKRITVEESLSHPYLEQYYDPADEPVTEEPFTFETELDDLPKERLKELIFQETL NLGEKELTPPKTTPEWVKFCKTMFSGFSLLLWIGAILCFIAYSIQATAYEDPPGDNLYLG IVLTAVVVVTGCFSYYQEAKSSRIMESFKNMVPQFALVVRSNDKLNIRAEELVIGDIIEV KFGDCVPADIRVINAHGFKVDNSSLTGESEPQSRSPEFTNENPLETKNVAFFSTNAVEGT CRGIVIGIGDRTVMGRIANLASGLEMGETPIHKEINHFIHIITSVAVFLGVSFFLIAFIL GYYWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTI CSDKTGTLTQNRMTVAHMWFDNRIVEADTTDDQSSATYDKNSPTWLALARISMLCNRAEF KVGQENVAVLKRECNGDASESALLKCVELSLGHVTEYRDRNKKVCEIPFNSSNKYQVSIH PNDQRYLLVMKGAPERILDRSATILIHGEEKPLTEEWRQAFNQSYLELGGLGERVLGFCD YILPLDQFPVGYPFDADEENFPLTGLRFVGLMAMIDPPRAAVPDAVGKCRSAGIKVIMVT GDHPITAKAIAKGVGIISEGNETVEDIAQRLGIPVGEVNPRDAKACVVHGSDLRDMTPAQ IDDILSHHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIA GSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLLFILAD VPLPLGTITILCIDLGTDMVPAISLAYETAESDIMKRQPRDPIHDKLVNNRLIGMAYGQI GMIQASAGFFIYFVILAENGFWPSRLFGIRKEWDAKGINDLEDSYGQEWTYAQRKVLEYT CHTAFFVSIVIVQWADLIICKTRRNSVIHQAMHNNHMVFGLFFETTLAAFLSYCPGLDKG LRMYPLRFTWWLVPLPFSALIFIYDECRKAILRRRPGGWLEIETYYSFKKLSKGKKVALS AAAGGVGVGVALTDLQLHPPHLPWSHSGIFSTFDHASIRRGYQVYKQVCAACHSMNYLCY RNLIGVCMTEEEAKAEAEEVLVTDGPNDLGEMFQRPGKLSDRFVQPYANDEAAKAANNGA LPPDLTLMALARHGEEDYIYHLLTGYCDAPAGVEVAEGQHYNPYFLGGKISMAQALYNEI IEYEDGTPATQSQLAKDVCTFLRWSAEPEHDDRKRMGMKGMALILAVIIYHYKRHKFTTM KNRKF-WIPPNLSKKCKYHSKTDTKNPHSYKPTKQKILPDILHAIGNTPLVRLNKIPKAE GVEAEVLAKCEFLNPSGSLKDRIALRMVTDAEDDGRLKEGGVLIEPTSGNTGIGLGMVAA VKGYRMIAVMPEKNSNEKVYTMRAEGVELVRTPSAASFYTPESAYRIAYKLGDVIPNSVV LDQYRCASNALAHYDTTAEEILEACDGKLDMLVVGTGTGGTLTGIERKIREKCPNCKIIG VDPVGSQLAFPQ--GSCNVEGIGKDFVPTVCDRRPVDKFYKCVDKESFQMARRIIREEGL LSGGSSGAVLHYGLEAAKHYGLKKGDRVVVLFADGIRNYMTKFLSEDWM-----XXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMP DIMRLITKDLSEPYSIYTYRYFIHNWPKLCFLAMDGDKCVGAIVCKLDMHKKMVRRGYIA MLAVDQDYRRKKIGSNLVMKAIRGMMEDDCDEVVLETEITNKAALMLYENLGFVRDKRLF HYYLNGVDALRLKLWLR------------------------------------------- -------------DDASKGKFAFTTEEYDMFEVCFETKMPHGGQGADREVFLNMKHGVEA KNYEDIAKAEKLKPLEVELKKLEDLSESVVNDFAYMRAREEEMRDTN-STHSRVLYFGVF SMLCLLGLATWQVLYLRRFFKSKKLIEEMETGRTSSVGNDILGFGGKVVNKPDHGNLDWS KICEQASKVVTFIDLAGHEKYLKTTVFGMTGHAPDFSMLMIGANAGIVGMTKEHLGLALA LSVPVFVVVTKIDMCPPNVLQDTLKLLQRILKS--------------------------- ------------------------------------------------------------ ------------------------------------------------------MTAPHM HPQACWEFEGEILVLHHPTTISCRYQAMVHVGSVRQTATIISMTVEHLRTGDKATVRFRF IKNPEYLRTDMKMVFREGRTKAIGSVTKLYPHVSANTRQQRAAKKAEE------------ ------------------------------------------------------------ ---------------------------YHTFRGHSAEIVCLAFNPSSVIATGSMDTTAKL WDVITTLTGHSAEIISLAFNTTGSQLITGSFDHTVSVWDKRIHTLIGHR----------- ------------------------------------------------------------ ETLSGHQGAVMACCFSPNGCLLASASGDKTVRLWDPLKGEAVQV---------------- ------------------------------------------------------------ -----------------------------------------DCNESTIKENYVIVYELLD EMLDNGFPLAVELNVLKEMIRPPNVLNKVTNKITGRS-NVSDTLPTGQLSNVPWRRTGVK YTNNEAYFDVIEEIDAIIDRSGATVFAEIQGYIDCLIKLSGMPDLTLSFVNPRLLDDVSF HPCVRFKRWESERILSFVPPDGNFRLISYHIGSQNMVAIPVYLKHSIAFRDGSSGRLDIT VGPKQTMGKTVENVVIEIPFPKAVLNVTATPSQGKYSFDPVTKMMSWDVGKIDTGKLPNI KGTINLQSGCPVPESNPPISVHFSISQLAVSGIKVNRLDMYGEKYKPFKGVKYVTKAGKF QVRTMATYVKPGTRHATSDWFTSNYTISTNAERQRGASHDVRQESRFLRNETDNKTKWDQ LDNNTRLADRVDNIRTWKDILERTLANIDKEIADLNESKDCLENSLEAKNLPTEVNVENL VTREGRQRIDIVEDEVEDQLHKEQEVIEGIKKQLQGKIDEAFEQLCVLQEARQQILADLQ DKNIALGIDVDQYNLTENSAGISFKPDSLRVPKGSTNPQNWEDFSRYNKDRAEAEMDASK RLREAIHHTLQQTDNDLAAQTTNTNYAYRKRIHEYERSIDELNWQKNKTEEEIAELEEDI RRVADAIRAKINPTKLAQTRLENRTYRPNVELCRDNPQYGLTDEVKQLEASKAALEDKLK QSQHALDGLEQNLHRINEDLQVKTNSLKLDDQCMGTRNKLEKNISLTGITNLKDVLANKI PAEQKRVSDFRKKHGKAVVGEVTIEQIYGGMRGIKGLATETSVLDPDEGIRFRGYSIPEC QEKLPRAAGGAEPLPEGLFWLLATGDLPTDEQVKAVSKEWANRADLPSHVVTMLNSMPSK LHPMSQFSCAITALNSESKFVQAYQQGVNKATYWEYVYEDSMDLIAKLPTVAAIIYRNLY RDGTSVGAIDPEQDWSANFVNMIGYEDATFTDLMRLYLTIHSDHEGGNVSAHTTHLVGSA LSDPYLSFAAGMNGLAGPLHGLANQEVLLWLTKVMVSDEVLTEFIWSTLKSGQVVPGYGH AVLRKTDPRYTCQREFALKHLPDDPMFKLVSQIYKLVPNILLEHGKAKNPWPNVDAHSGV LLQFYGMKEMNYYTVLFGVSRSLGVLSSLIWDRAFGLPIERPKSLSTDKLMELAKMPFQP PKQEKCTTCGKSVYQAERQEAGGNIYHKMCFKCTVCKMSLKLNNYSQDSGNLYCKNHFQE FITSKNTQADQLFVHRDSSENNADVKFEFTKTNLERASNIISNYPDGHQASACLPLLDLA QRQNNWLPITAMHAVADLLKMPRMRVYEVATFYTMFNRNPVGKNLVQICTTTPCMLGGVG SDIILETIKNKLGIEVGETTKNKMFTLAEVECLGACVNAPMVQINDDYYEDLTPKDMEEI LDDIIAGKKPKPGPRSGQDQRFASEPKGGLTSLTEPHPGPGFKCRSDLMQKYEKLEKIGE GTYGTVFKAKNRESHEVVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHS EKKLTLVFEY-------------------------------------------------- ------------------------------------------------------------ -----------------------------PTEDSWPGMTQLPEYKAFPMYHVNQQVVPKL NGKGRDLLLNLLICNPTKRMSAEDGMQHSYFADLNPAVK--------------------- ------------------------------------------------------------ ----RGKKKYVTVITGLATYDIDLKKASKAFGSKYACGSSVTGPDEIVIQGDVKDDLWDF IPEKWPEIDEDAIDDLGDQKR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------LFQEAKEKSEIQRMV ISGGNFRPDVLKPKEVVSLLLDDDEMEKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXMPRFTPYLTKEQEDELRKIANAIVAPGKGILAADEST GTMGKRFAQINVDNTEENRRQYRQLLFSPSADHISGVILFHETFYQKADDGTPFVKILQD NGIIPGIKVDKGVVPLGGTDNETTTQGLDGLAERCAQYKKDGAGFCKWRCVLKIQSHTPS YLAMIENANVLARYATICQQNGLVPIVEPEVLPDGDHDLETAQRVTEEVLAFQYKALQDH HVFLEGTLLKPNMVTAGHSCSKKYTPEEVAKATVTALQRTVPSAVPGVTFLSGGQSEEDA TIHLDAINKKPWSLSFSYGRALQASVLQAWKGKKDCVAAAQQELLKRAKSNGMAAMGQYG GGTAGAGAKSLFVADHRYYIQSLPKVVKRKIKALKKLQNEMIKIESKFYEEVHELECKYA SKYAPFMERRKEILTGNMEPTDSDCDWPSDEEDAEEKAQIEDEESPVGIPGFWSTIFKNV DLMSEMIQDHDEPILNHLHDIKVKFSAGFSLEFYFDTNDYFSNTVLTKEYILRTEPDPTD PFSFEGPEIIKCKGCAVDWKKGKNVTVKVIKKTQKHKGRGTKRTVTKTVQNDSFFNFFSP PQVTEGEPDEDTEALLAADFEIGHFIRERVVPRAVLYFTGEALDEEEENEDED--IILLK EGTDSSQGKPQLISNINACSAIVDAVRTTLGPRGMDKLIVDNNGKATISNDGATIMKLLD VVHPAAKTLVDIAKSQDAEVGDGTTSVVLLAGEFLKQAKPYVEEGVHPQIIVRAFRKATH LAVQKIKEIAVRIPKDAATHKSLLLKCASTALSSKLVAHQKDFFASMVVEAVMSLDELLP LNMIGIKKVQGGALEESQLIAGVAFKKTFSYAGFEMQRKEYHNPKMALLNIELELKAEKE NAEIRVDSVEEYQSVVDAEWSILYSKLEKIYTSGAKVVLSKLPIGDVATQYFADRDLFCA GRVTEEDLKRTMKACGGSIQTTVANLSLGTCELFEEQQVGGERYNLFKGCPQAKTCTLIL RGGSEQFIEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRNYSRTIPGKEQLL IGAMAKALEIIPR----------------------------------------------- --------------------------------------------XXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- --------------------------RVTAVITCFPYARQDKKDKSPISAKLVANMLSVA GADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIQDNIAEWRNSVIVSPDAGGAKRVT FIADKLNVEFALIHKERKKANEVASMVLVGDVKDKVAILVDDMADTCGTICHAAEKLLEA GALKVFAICTHGIFSGPAVSRINNSSFEYVTVTNTVPQESAMKHASKVQCIDISMILAEA VRRTHNGESISYLFSNVPLISCRFYEHRFPEIEDVVMVNVRSIAEMGAYVHLLEYNNIEG MILLSELSRRRIRSINKLIRVGRSECVVVIRVDKEKGYIDLSKRRVSEEEVLKCEEKFAK AKAVNSILRHVGEIIGYESNEQLEDLYTKTAWHFDRKYNKPGSSYEAFKHAVTNPEILDE CNLDKETLEVLQANIHRRLTPQSVKIRTDIEVACYGYEGVDAVKSSLKSGLAMTTEDMPI KINLIAPPLYVMTTQTLERAEGMARGQQKIQSQQKNALKTQKAKHDGKKDAAKALVFSCS VCKTQMPDPKTYKQHFENKHPKSELPAELKE-MLGSLQSDMTRQGITTVPKGHCTACRKP IIGQVITALGQIWHPEHFACAHCNHELGTQNFFEREGQPYCERDYHTLFSPKCAYCAGPI LDKCVTALDKTWHPEHFFCAQCGRPFGEDGFHERDGKAFCRDDYFDLFAPKCGGCGGPIM DNYISALSRQWHPECFVCRECHMPFGGGSFFDHEGMPYCETHYHARRGSLCAGCQKPITG RCITAMYK-----------------------------------------LTDEETKTFFE KLSKYIGENIKLLIDRPDGTYCFRLHKDRVYYVSEPLMKRAGNIARENLVSFGTCFGKFT KAGKFRLHVTALDY----------------------------GLGRITENTPQYQGLVVY SMNDIPLGFGVSAKSTQECRHTDPMTIIAFHQADIGEYIRSEDTLASERKLFVGGNWKMN GNKKSIDGIIKFLKDGYPATDVVVAPPAIYLDYVQTNLIGVAAQNCYKVEKGAFTGDISP AMIKDVGVEWVILGHSERRHVFGESDQLIGEKVAHALAAGLNLIPCVGEKLEEREAGKIE EVVFRQTKASDWSRVVIAYEPVWAIGTGKVATPEQAQEIHCKLRNWIKDHVSAKVASEVR ILYGGSVSASNCKELAKKPDIDGFLVGGASLKPDFIQIINSR------------------ ------------------------------------------------------------ ------------------------------------NFHLSFKDGLAFCALIHRHRPELI DYYKLSRDNPLENLNTAFDVAEKYLDIPRMLDAEDMVNSPKPDERSVMAYVSSYYHAFSG AQQAETAANRICKVLKVNQENERLMEEYERMASDLLEWIRRTTPWLENRTTDNTLPGTQR KLEEFRDYRREHKPPKLEEKAKLETTFNTLQTRLRLSNRPAYMPTEGKMVSDIASAWKGL EFAEKGFEEWLLSEMQRLERLDHLAQKFKHKCAIHEEWAFGKEDMLQSQDFKQCKLNELK ALKKKHEAFESDLAAHQDRVEQIAAIAQELNALDYHDVVTVNARCQRICDQWDLLGTLTQ SRKNALDEAERILERIDQLHLEFAKRAAPFNNWMDGAKEDLVDMFIVHTTEEIQGLIDAH EQFKQTLGEADKEFNSIIQLVQEVTRIAQQYGIMGGSENPYTTLSAQDIAHKWTDVKQLV PQRDSVLQQEMLRQQNNERLRRQFAQKANVVGQWIERHLDAVASVGMGRGSLEEQLNKLN AMETEVMSYKPNIDELERFNQEVQESMIFENRHTQYTMETLRVGWEQLLTSVARNINEVE NQILTRDSKGITNEQMDEFRKSFNHFDKNRTRRLEPKEFKACLVSLGYNIRDDRQGEADF QRIMSIVDTNHTGYVTFDAFLDFMTRETTDTDTAEQVMQSFKILAGDKAYITAEILRREL PPDQAEYCIQRMAPYTGRDGEPGALDYMSFSTALYGESDLNKLSIKSLDLKGKRVLIRVD FNVPLKGEVITNNQRIVAALPTIKHALDNDAKSVVLM----------IXKYSLKPVADEL KKLLARDVQFLSDCVGAEVESACANPTAGSVILLENLRFHPEEEGKGVDKEGKKVKASPE AVEAFRASLSKLGDFYVNDAFGTAHRAHSSMVGCQLPKKAAGFLLNKELTYFSKALDNPV RPFLAILGGAKVKDKIQLIESMLDKVNEMIIGGGMAYTFLKVLHGMEIGNSLYDEEGAQI VKKLMDKAKSNNVKIHLPTDFVNGDKFAEDAKVGRTTISEGI----MGLDVGAETVKTFT EAIGRAKTIVWNGPAGVFEFESFAHGTKAIMDAVVKATEEGTTTIIGGGDTATCCAIWNT EDKVSHVSTGGGASLELLEGKTLPGVAALSDAMAGIPPKTWQPPTVTLETTLGTIVFELY WKQAPNSCRNFAELARRGYYNDIKFHRIIKDFMIQTGDPTATGRGGASIYGKQFDDEISN ELKHTGAGILSMANSGPDTNGSQFFITLAPTQWLDGKHTIFGRICSGMTVVDKVGKVETD TSDRPVEDIKMV------------------------------------------------ ------------------------------------------------------------ ----------------DGIHFQGQSLKIRRPRDYQPLPGMSETPSVGVVSTVVQDSAHKI FLGGLPNYLNEDQVKELLTSFGPLKSFNLVKDSATGLSKGYAFCEYVD------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------GILIPEKAQGKVLEATVVAVGPGSR ANNGNVVAPSVKVGDHVMLPEYGGTKLRFEDKEYFLFRDGDILGKFE------------- ------------------------------------LWLGANVMLEYNLDDAEELLSKNA ANKEITKVDDNLAFLRDQITTTEVNKARLHNWAVKNRQAQKSMADDALSRHGLHFDELNK IRVLEPEVSQQTSELKEECKEFVDKISEFQNIVGGFIDVIDNVSKEVEKEKMKAIGSRNL LKSIAKQREAQQQELQALITEKKMQLERLRIQFESLQKEEGEQNEFIEQFILQK------ ----SRDRRRSRSRDRHDLTPEERDARTVFCMQLSARIRPRDMEEFFSSVGKVKDVRIIT DNKTRRSKGIAYVEFKDCESVPLAIGLNGQRLLGVPIIVQPSQAEKNRLAANSGPMRLYV GSLHFNITEDMLRGIFEPFGKIEHINLVMDIETGRSKGFGFVTFEDSEDAKKALEQLNGF ELAGRPMKVGHVTERTAEGSVLDSDEMDRAGIDLGATGRLQLMAKLAEGTGFEIPSNVAS ALNMNSAQASPPIATQCFMLSNMFDPTTTNMNWDQEIRDDVIEECNKHGGALHIYVDKAS PQGNVYVKCPSISAAVASVQALHGRWFAGKVITAAYVPLPNYHQLFPDALRTIQLMMPST ------------------------------------------------------------ -------------------IHRHGGEVIIQQGDEGDNFYVLDQGEVDIYVNGEWVSIIGE GGSFGELALIYGTPRAATVKAKTDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLGKVSIL ENLDKWERMTVADALEPVQYEDGHEIVRQGDAGEDFFIILEGSASVLQRRSDNEEPVEVG KLGPSDYFGEIALLLDRPRAATVVSRGPLKCCKMDRQRFERVLGPCGDILKRNIQQYNSF VSLSV------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------ALASFDRQELQKNVISSSS FKLFLELEPQLRDIIHKFYESKYASCLKLLDEIKDNLLLDMYLALHVNTLYTQIRNRALC QYFSPYLSADMNKMASAFNTTVISLENELMQLILDGQINARIDSHNKILYAKDIDQRSTT FEKSLAMGKEYQRRTKALILRSAMLKNQLHVKSPPRDASQGGEMSIAPGTA--------- ------------------------------------------------------------ ----------------------------------------------DIKFLCRNLALSGG VILLLAESKAEGRSLFAGLPSMGENTPKTYMQLSGRLLLVLMFLTLLRFEFSFFQMVQNL VGTALIVLVAIGYKTKLCALILVVWLTAINVYFNAWWNIPQNRPMRDFLKYDFFQTLSVV GGLLLVVALGPGGYSMDEHKKKWRHTVTLLAGDGVGPELMGHVKEVFRFAGAPVDFEDIK LDRNGVALKGNVETRAKSRNIELRKELDLFANVVCCKSIPNIKTRHSDIDLVIIRENTEG EYKQLEHENVAGVVESLKIITRENSLRIAKFAFDYAKRHGRKKVTAVHKANIMKLGDGMF LECCRQVADDYPDIQFEAMIVDNCCMQMVSRPQQFDVMVMPNLYGNIISNIGAGLVGGPG IVAGVNLGQEYAVFEMGTRGTGKSIASKNIANPSAMLLAGADMLEYLGLKDHSAIIQNAV YKVMSEDQIHTPDLGGLATTLD---------TEDFKHFVDRASRVIERALSEHVDLFTDY AGGEREDVLQEGEKLKLNRQFYDERWSKHRTVTCLDWSTQHPELLVASYNNNEDAPHEPD GVALIWNLKYKKTSPEYIFHCQSAVMSTCFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPA QRTPLSAAAHTHPVYCVNVVGTQNAHNLISVSTDGKMCSWSLDMLSAPQDSMELQHKQSK VAVTSMSFLSGDVNNFVVGSEEGAVYTACRHGSKAGIADMFEGHQGPVTGIDSHTVPGQI DFSHYFLTSSFDWTIKLWNMKDSKPLHSFEDNSDYVYDVKWSPIHPSLFASVDGMGRLDL WNLNHDIEVPIASSYNVSLNRCRWHQTGHQIAVGDDLGKIHIYDVGEHVATPRSDDWNKF VHALQDIRNNQNDQDDD----------------------------DDDFEMLRQRRMQQM KKLTDQKKDWLSQGHGRYEEISDEKEFFNVCKKSSKVVCHFYRDS-----XVDKHMAILA PKHVETRFVKINAEKCPFLTERLRIVVIPTICLAKDGKTVDYVVGFDDLGGHDEFHTDVL EWRIARADVINYSGDLMTPPTTG-------------RTVTLTGYGGIRMMKIKKRATPSE GEVLIRVKACGLNFNDLIVRQGGVDNPPKTPFVLGFECSGEVEALGENTAGFTVGDRVAA ITNAWSELVVFVYKMPTGMSFQDGAALPMNYITAYMMLFEIANLKQGDSVLCHSVGGGVG HAVSQLCKTVPDVTLFGTASYKHEAIKNN-VTHVFDH-VVDYCQEIRKVSPEGVDIVLDC LCGEDANKGVSLLKPLGRYILYGSSNIVTGETKS-------------------------- -------------LIQMYNDGKIKPKIDSVWSFDDVGKAMAQMHERKNIGKVILVPHK-- ---------------PVVVKLNSGVDYRGVLACLDGYMNIALEQTEEYVNGQLKNKYGDA FIRGNNVLYISTQTRR-----QGALLLRKQLGELNKCPMEGFSAGLIDDDDIYRWEVVII GPQDTLYEGGFFKAHLTFPKEYPQKPPKLKFISDIWHPNIDKSGDVCISILHDPGEDKYG YERPEERWLPIHTVESIMVSVISMLTDPNSESPANLDAAKEHRENKEVFKKKVAKCVRKS QE---------------------------------------------------------- ------------------------------------------------------------ --------------------------------------DFPLSGYTEVRYDDEVKRVVIE PIELSQEFRKFELGNPWESFPAHRQ------------KFWACNFCFQRNPFPPQYASISE QHQPAELIPQFSTIEYTLTRASCNPPVYLILLDTCMEEEDLQAVKESLQMSLSLLPPNAL IGLITFGRMVQVHELGSEGCSKSYVFRGTKDLTAKQIHDMLGIGRGTAQLPSNRFLQPVH KCDMALTDLLSELQRDPWPVAQGKRPLRSTGAALSIAVGLLECTYPNTGARIMLFIGGSC TQGPGMVVGDELKNPIRSHHDIEKDNCKYMKKAMKHYESLSTRTSTNGHIIDVYSCALDQ TGLCEMKYCTKYTGGHMVMGDSFNTSLFKQTFQRVFSKDTKN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------QSLIMIQPILYAYSFNGPPEPVLLDTSSMQPDRILLMDTFFQ ILIFHGETVAQWRKQGYQDLPEYENFKQLLQAPVDDAQEILQTRFPMPRYIDTEAGGSQA RFLLSKVNPSQTHNNMYTEGGGHVLTDDVSLQVFMDHLKKLAVSSAS-----NEVQMKMI AELEIEMMSDMYTRMTNSCHKKCVPPKYKDADLTKGESVCLDRCVAKYMEIHDRIGKKLT NMSMQDQEAVKKFQTTQQPAVIHKVIMV---XXGKSALTLQYMYDEFVEDYEPTKADSYR KKVVLDGDEVQIDILDDYA---------------------------------QILRVKND DNIPFLLVGNKADLEDKRKVTIEESQVKAQQWNVPYVETSAKTRANVDKVFFDLMRLIRS KKQVKRSGKKKCVIL--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------D MTVSNTTMEEFKSHVQQGTNLYGVDLFVRVLTTGFWPTQSATPKCNIPLAPRQAFEAFRR FYLAKHSGRQLTLQPQLGSADLNASFFGTKKEEGDSKTSSRKHIIQVSTYQMVILMLFNN RDRLTYEEIKNETDIPERDLMRAIQSLALGKITQRILVKEPKTKEIEPEHIFAVNDQFTS KLYRVKIQTVAAKGESEPERKETRGKVDEDRKHEIEAAIVRIMKARKRMQHNVLVAEVTE MLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKIYTYVADRLNVFPSRMAQTIMKGRLK GAQKGHSLLKKKADALTMRFRLILKKIIDTKQLMGDVMKEAAFSLAEAKFTTGDFNHIVL QNVTKSSIKIRSLKENVAGVQLPVFEHFTDGTDSYELTGLSRGGQQIDKLKKNYAKAVEL LVALASLQTSFVVLDEVIKVTNRRVNAIEYVIIPRIERTLAYITTELDEREREEFFRLKK VQKKKQQIR--------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------------------LDQ NRAQAQIACRNDVSNVIIWGNHSSTQFPDVSHAKVVKDVVKDDAWLKGEFIKTVQLRGAA VIKARKLSSAMSAAKAICDHMRTWWTGTKEGKYTSMGVVSDGYDIPAGIVFSFPVQIDHS YKIVQGLAIDNCCRERLDKTLKELEDEKAMAEDACGSNSGVLMVGPNFRVGKKIGCGNFG ELRLGKNLYNNEHVAIKLEPMKSRAPQLHLEYRFYKQLGQAEGVPQVYYFGPCGKYNALV LELLGPSLEDLFDLCDRKFSLKTVLMVAIQLITRMEYVHSKHLIYRDVKPENFLIGRQSN KKQHIIHIIDFGLAKEYIDPETHKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEAL GHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEELAQYLRYVRRLD FFETPDYDYLRKLFQDLMDKKGWDCDWEFDWTGRQL------------------------ ------------------------------------NLDPLTETYGLPFYMQYLAHWPEY FQIAESPSGEIMGYIMGKAEGHGENWHGHVTALTVAPPYRRLGLAAKLMNILEE------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------VVEVQEKSGGRNAHYKLTST AMLWLQTNKVGSGTMNLGGSLTRQNEIDASVSESNPHVVNIGRMVED-------TLNEIY FGKTKDIVNGLRSTQSLQQESMQRDLKTALAKRGQXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXDKLTIGARARAPAGDTAFTLGRGAVAGASVFGIG ALCYYGLGMSNQMGAVDRALLWPEVVRLRIKDTYMYFGGGIIVTAVARNPALMRMMTKQS WLAIGATMAAMIGSGMVCRSIQYKPGAKQLAWMAHAGIMGAVIAPLAFLGGPILIRAAWY TAGVVGGLSTLAMCAPSEKFLNMGAPLTMGLAVVFASSIGGMFFPPTTALGAGLYSVSIY GGLILFSMFLLYDTQKIIKRAETHPVYAVQPYDPVNASIGIYLDTINLFIRIAMILANGG GKRK-----------------------------DITPDTSLLESFVERNPVDIGIQCAQE MSEHEVNTERFETDSRGINHTEGGWPKDVNPQEVEQVIRFRKKVEKDEMYINTIQQLGSV MEHCIKQNNAIDIYEEYFGDVDAEGADECPSAKTINVFRDPNEQKRTSTHISWFPDGPRK LAIAYCNLEFQGSSPDTMDSYIWDIENPNKPEMTLKPVSPLVCLEYNPKDSHVLIGGCYN GQIAYWDTRKGSQPVEMSPIEHSHRDPAYKTIWIQSKTGNDCFSASTDGQVLWWDIRKLG EPTEKLILDPTKKQDITKAQGAFALEYESTIPTKFMVGTEQGSVLSCNRKAKTPQEKIVA VYPGHHGPIYALQRNPFFPKNFLTVGDWTARIWSEDIRESSIMWTKYHMAYLTDGCWSPI RPAVFYTTKMDGTLDIWDFIFKQNDPTLSLQVCDEALHSIRVQEQGRLIACGSQSGTTTL LELSDGLCTLQRNEKTLVTAMFERETRREKILDARHREMKLKERTKSSWEDLVEFVTPIA NPLASKKLAKKLYKVIRKALRKGVKEVQKFVRKGEKGIVVFAGDTSPIDVICHMPVVCEE VGLPYCYTPSKEDLGAATGSTRPTCMVMIKVDDDYQELYDKCYSEVKGLP----PAENLE EEGLEKNPNLELSQWKFLLTTDQYKNNEDIKKQLLAVIKSDNMAPFYEEVCTELGWKVDQ EWLKQMKETNEAELKKLDEAVEDAEKNLGETEVRDGMLKKGEYLIKIGSKEAALTQFRKT FEKTHTLGYKLDMVFHLIRVGLFYMDHDLITRNIEKAQSLIDEGGDWDRRNRLKVYKGTY NMAIRDFKSAANLFLDTVATFTSYELMDYKTFVTYTVLCSMIALERPNLKEKVVRGSEIL EVLHSLPDIRQYLFSLYNCQYADFFKSLAHVEQMMKTDRYLSPHFRYYNREMRVHVYAQL LESYRTLTLDYMAKAFGVSVGYIDQELSRFIAQGRLHCKIDKVGGIVETTRPDSKNWQYQ ATIKQGDILLNRIQKLSRVINITRGLQTSAEKIVGIPYKNLSIGVPKELFQNEKRVALAP ATVATLKKGFTVNIEENAGVLAKFSNDDYAAGGANIAVNDIYKSDIILKVRAPLTEEVNR FNEGNTLYSFLYPAQNKELMDQLAARKLTAFAMDCVPRISRAQVFDALSSMANIAGYKGV LEAANHFGRFFTGQITAAGKTPPAKVLVIGAGVAGLSAIGTAKNMGAVVRAFDVRSSVKE QIQSMGAEFLEVNFKEEGEGTGGYAKEMSPEFIEAEMALFAKQAKECDIIVTTALIPGRP APKLIKKYMVDAMRPGSVVVDLAAEAGGNIETTRPGEVYSYNDVVHIGYTDLPSRLPAQA SSLYANNISKLLLSVGYNVDLEDEVVRGSIILHEGKMMWPPPKPLPPNYFNITLKDSLMY TAGLGTIAGLGMISPNPAFSTMMTTFGLAGIVGYHTVWGVSPALHSPLMSVTNAISGITA AGGLLLMGGSYLPTSTAHVLAATAAFISSINICGGFLVTQRMLDMFKRPDDPPEYNKLYA VPGAVFLAGYGYAAMGDYPEIHQMAYLAASLCCVGALTGLSSQKTSRVGNALGVIGVTTG IVATLGLLKPTPELMVQMGTCMGLGGLIGTVMAKRLEVTDLPQMVALFHSLVGAAAVLTC LANFLVEYPHFDTDPAAGVIKTALFLGTFIGGVTFTGSLIAFGKLQGLLKSEPLLLPGRN FLNGGMALANVAALGYYMTTNDTACLSMLGTTTVLSSVMGVTLTAAIGGADMPVVITVLN SYSGWALCAEGFMMNNNLMTVVGAMIGSSGAILSYIMCKAMNRSLPNVILGGYGTSSTGG GKAMVITGTHTETDVDQTVDMITSAQNIIITPGYGMCVAKAQYPIAEMITTLREKGINVR FGIHPVAGRMPGQLNVLLAEAGVPYDVVLEMDEINDDMTVTDLVLVIGANDTVNSAAEED PNSIIAGMPVLRVWLSKQVIVMKRSLGVGYAAVDNPIFYKENTAMLLGDAKKTCDALL-- --MQAPQAPPDCPPGLEYLTMIDQLLVHQQVELLEAFTGFETNNKYEIKNSMGQRVYFAA EDTCCCTRNCCGNNRPFEIQIMDNQGREVIHLSSPLRC--DTCWFPCCLKKVEVQAPPGQ VVGYIKQAICKPKFYLQTAVLQINGPCFTCN--IC-GDVEFDVTSTQVGRISKQWTGLIK EMFTDADNFGVAFPMDLDVKMKATMLGAVFLIDFMFFEKEGN-ADAELQQFIAMETQKAQ FQKTIHELTDVCWEKCMDKPRDKLDYKTEGCVSNCVDRFVDTTLIITQRFQQLIQK--MN RSEGLVQRRTTTVEDEDHDSKETRLTLMEEVLLLGLKDREGYTSFWNDCISSGLRGCILI ELAVRGRVELERTGMRRKSLLNRKILVKSEAPTGDVLLDEALRHMKETQPPESVQSWIEY LSGETWNPLKLKYQLRNVRERLAKNLVEKGVCTTEKQNFLLFDMTTHPLTDNTFKSKLVK KVQDAVLSRWVNDPHRMEKRLLSLLYLAHASDVLENAFAPLSDDDYEVAMKRVRDLLDLD FEQESMKEGANELMWCVISAFSKQSRIDKITEENCEVCVKFMARFMNGLDKIENAFRKQC KNTIKDDNRFCYYVGGLEESATGILGEMSRPVSIGMPPEKVCGKLKNKDSQICDLKYDKT IDLTNVKLKKLKVKDLKKILSDWEEQCRGCAEKSDYVKKVEELMPKYAPDAW---ILNGF KLNWMNLRDADSGKILWQGSEDLSLPEKEHEARVPKKILKCRAVSREINFSSDEQMDSFR LEQKVLFKGKCLEEWYFEFGFVIPGSTNTWQSIIEAAPESQMMPANVLNGNVMIETRFFD GDLLVSTSKVRVFYV--------------------------------------------- ------------------------------------------------------------ -------------EIRKDVYSQIAQPKKVTLTKHTKNMGKFSSVTVSTVDEEEDEIEAKE IADSYAANARVIEKQLLRKGINKRKLLEQAELEAKKMRPKGTLID------------QNR SYADMAFTLSAPGEVKVKQVDVPSFSGNFGILPDHVPLLAVLKPGVITVTEXDGSTNKIF VSSGSVTINGDSSVQILAEEAVSVGQLDAQSIREGLNKAQQE--XDDAKAEAEISLECFE SLAKALECKFLATELKSRLDETGKSREVIETGYAFDKKKRIKYKTSELRLTEALHEPHIC EKILQYNVHAERKGSLRYAKGRSETMETLHGLVNKGVKVELGIPYELWDKPSAEVTVMQR SCFKMVEDYEDDIEDWYYNQQSDIIKFLCEDKVLKKEEQVFAPTDVTSEDDVTNALIAKN KFGRLDIAVNCAGIGIACKTYNFKKDVPHSLELFQNVLKVNATGTFNVTRLAVGLMGKNE PSPDGQRGVVVNTASVAAYDGQIGQVAYAASKGAIVAMTLPMARDLASCGIRVNVIAPGL FDTPLLAQLPEKVRTFLASTVPFPSKLGLPDEYAHLVQTIVENPMLNGEVIRIDGALRCR DFHFRVHGQNAESKGQISRDYPVIDHTYDAVVVGAGGAGLRAAFGLANEGFKTACITKLF PTRSHTVAAQGGINAALGHMEEDDWKYHFYDTVKGSDWLGDQDAIHYMTEEAPKAVLELE NYGMPFSRLENGNIYQRAFGGQSLKYGTGGQAHRCCAVADRTGHSLLHTLYGRSLYYDTT YFIEYFALDLIMEEGECRGVIALSLEDGTLHRFHSKNTVLATGGYGRTYFSCTSAHTCTG DGTAMATRAGLANEDMEFVQFHPTGIYGAGCLITEGCRGEGGYLLNSEGERFMERYAPNV KDLASRDVVSRSMTLEIREGRGVGPDKDHCYLQLSHLPLDQLKSRLPGIMETAMIFAGVD ATRDPIPVLPTVHYNMGGVPTNYKGQVIQVDHKDYIVRGLYACGEAACASVHGANRLGAN SLLDLVIFGRACALTITEENKPGDKIGPIKDNAGEESVANLDKLRYADGKTPTADLRLRM QKTNQTNAAVFRDGPSLQEGVAKMTKLYDEMDLKVSDRGMVWNSDLVETLELQNLMLNSM QTVVAAEARKESRGAHAREDFHERIDEYDYTKPLESQQKKPLDKHWRKHSLSFQNADTGK VTLEYRPVIDHTLDKTKVDTIPPKIRVYMTALSQEEIIGSSKTVVQGLDTLKNEHHQILN SLLSSMKTIKKGDTNLVEEKTSILKKSLEMLELGLGEAQVMMALANHLQYVEAEKQKLRA QVRRLCQENAWLRDELASTQQRLQHSEQRVATLEEEKKHLEFMNEMKKYDSDQPLGFPED DEDGSTSVMAQAASGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHD HPDVATMLNILALVYR----------------------------TVTTTLKNLGALYRRQ GKYEAAETLEECAMRSRK------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --TMGGVRHVADIRADDMSRDSAGHIGLQAGNKFASQKGMSI-----------DDMSADS AGHIGLQAGSNKGASQKGMSIGAVRHVSDIRADDMSVDSAAYIGLQAGTNKCASQKGMSM GAVRHVADIRADDAIKTC--IGLQMGSNKGASQKGMVMGGVRHVADIRADDA-DKTSIGL QMGSNKGASQTGMVMGGVRHVGDIRSDDIAGKATINLQYQGNVGASQTGMSMGKQRRIMP EVHPFGIEPITCHAWNSDRTQLAIPNNHEVHIYQFKWNKTHELTEHQQRVTGIDWAPNSN TIVTCGADRNAYVWPTLVILRINRAATCVKWSPMENKFAVASGARVISVCYFEQENDWWV SKHIKKPLRSTITSIDWHPNNILIGCGSTDFKARVFSGYVKEIEEKPAATPWGKKMTFGN CMVEFSNGGGWVHCVSFSASGDKLAWVGHDASVSIVNSTLKTQQLPFMTCLWATENSLLV AGHGCVPMLFTHDGSQVTFVNKLEDQKITAMKHFQSLDKRATTLNTTHQNTITQLCTHMG NKANTAKFSTTGVDGQLVIWD--KEVDGYVGFANLPNQVYRKSVKKGFEFTLMVVGESGL GKSTLINSLFLSDLYSADYTGPSLRIKKTVQVETTQVVLKEGGVQLRLTVVDTPGFGDAV DNSNCWQPVTDFIESKYDEYLNSESRVHRRTTADSRVHCCLYFLSPNGHGLKPLDVEFMK RLHDKVNIIPLIAKADTMTPDECRDFKKTILNEIAQHKIKIYEFDDEEEKKIQKKLKDRV PFAVIGSNTVVESQGKKVRGRMYPWGIVEVENLEHNDFIALRNMLIRTHMQDLKDVTNNV HYENFRYSKLATVTKNPIAQMEEEKQEHVTKMKKMEAEMEQVFEMKVKEKKQKLKDSESD LQRRAEQMKKSIE-------------------------MSRRYDSRTTIFSPEGRLYQVE YAMEAIGHAGTCLGILASDGVVLSAERRNTNKLLDEVSNSEKIYKLNEDMACSVAGITSD ANVLTNELRLIAQRYMLQYQEPIPCEQLVTTLCDVKQAYTQFGGKRPFGVSILYMGWDKH YGFQLYQSDPSGNYGGWKATCIGNNSSAAVSMLKQEYKEGETTLKDALGLTIKVISKTLD TNKLTNEKVEIATLTRENGQTVIRILPAGEVAALIKVHEEQEAKAEAEKKKELNEAWERL KQLSLKRQERLYGAHEIQHFNRDADETIVWITEKDVMLSTEDYGRDLASVQALQRKHDGV DRDLAALEEKVQAMGGEADRLTETHEDQADEIRNKQAEIEDSWRRLRAKADDRKKRLDDS YYLHRFLADYRDLIYWIHDMKTIISADDLAKDVAGAEALLERHQEHKGEIDAREDSFKAT AEAGQLLLESDHYAVDEVKEKLVTLASEKTSLLDIWEERRILYEQCMDLQLFYRDTEQAD TWMTKQEAFLVNDDLGDSLDSVEALIKKHEDFEKSLQAQEEKIKALDEFATKLIENEHYA ADDVASRRDMLLTRRNALHTKCITRRQHLEESYRYQMFERDCDETKSWINEKLKTASDEG YLDPTNLQGKLQKHQNFEAELAANEPRIEAIDQDGNKLIEMEHYASDQILERLDEIHFLW SQLKEQSDRKGLKLREASDQQQYNRSVEDVEIWLAEIEGQVMSEDYGKDLNSVQNLQKKH NLLESDVGSHQDRVDGIVQSAMKFEEGGHFDADNIKVKQVQVVERYMALQDPIHGRKNKL TDALRLQQFFRDVEDEEDWMREKEPIAASTNRGRDLIGVQNLMKKHQALQAELAGHESRI ADVCEQGNQMYHEGHFASEDIKAKILGLQERWELLKEKSNQRKQDLEDSLQAQQYFAEAN EADTWMREKEPVVGNTDYGKDEDSAEALLKKHEALMSDIEAYRSVIEGLTDQANACKXQE QPVIDDLGKECVVALYDYTEKSPREVSMKKGDVLTLLNSTNKDWWKVEVNDRQGFVPAAY VKKIDASLTASQSNLADEFTISVRQTQIEHQYANLLDLGNQRRDKISESCKAYQLVREAG DLAQWINDKETVALDDVVGDDLEQVEVIQRKFDDFQKDLKANEVRLRELNTVADKLTSMG QTEAAEKIRVQIEDLNQRWAALQQVTQDRAEVLSSSHEVQRYHRDADETRDWIEEKDNAL NTDNIGDDLATVQRLQRKHEGLERDLAALGDKVRELDETANRLMTTHPDQAEAIYNHQKD INERWNVLTTKADTRKAKLLDSYDFQRFMSNFRDLNAWINSMMALVSSDELAKDVTGAEA LLERHQEHRMEIDARSGTFQAFEMFGNQLLQNNHYASDDVKDKLQELTDARELLEQAWVA RRAKLDQCLELQLFKRDCEQAETWMAAREASLADSVDGSSTVESLLKRHEDFDRAIHSQE EKIGALTAFADNLVDADHYDTDGIEREKAQVLERWANLKETLLDNRSKLGEAQSLQQFSR DADEMEIWLTEKLQSATDESYKDPANIQSKHQKHQAFEAELAANADRIKAVVNMGQKLVD KNQCAGSEDAVTERINTLAEQWEFLTIKSSEKSEKLKEANRQRTYNAAVKDLEFWLGEVE HMIETEDYGKDLATVQSLVKKHQLLDADINAHEDRINDLNEQADEFIQSGIWDVESIKIK KTTINERYERVRELAIHRRSRLGEANTLHQFFRDIDDEEAWIKEKKLLVGSDDYGRDLTG VQNLRKKHKRLEAEISSHEPSIQAVQETGQKLMEDSNLMTEDIQQRLQTLATNWDELKQM AQLRGQKLDESFVYQQFAANVEEEEVWISEKQHLLSGDDCGDTLAAVQGLLKKHDAFETD FQVHHDRCQEVNKEGEKLISEGNHNADAIGQRCATLQEKLTALHQAANLRKSNLIDNSAF LQFIWKTDVVESWIADKETQVRSEDYGRDLSSVQTLLTKQETFDAGLQAFEKEGIQTITA LKDQLVASNHAQTKAIEARYAAVIERWQKLLADSDSRKQRLLKLQEQYRQVEDLYLTFAK KASAFNSWFENAEEDLTDPVRCNSVEEIMALREAHEQFKASLSAAETDFNQLAALDRQIK SFNVGPNPYTWFTMEALDDTWKNLQKIIRERDAELGREQQRQEENDVLRKEFAQAANAFH GWVTETRAAMMEGSGTLESQLEATKRKASEVRAQRGQLKHIEDLGAAMEERLILDNRYTE YSTVGLAQQWDQLDQLGMRMQHNLEQQIQACNTCGVSEDALREFSMMFKHFDKDKSGKLD HYEFKSCLRALGYDLPMVEEGQQDPEFEAILDSVDPNRDGFVSLQEYIAFMISRETENVQ SAKDVEAAFRALTSGDKPYITANELYANLTKEQADYCVRRMKPYEDPKGRVLPDAYDYST FTRTIFVNAIQCYQCDSNEDKACPSYWPFDKRLNAMVDCSSFEANVPGTFCMKITQQSPG WGGWTKITRRCGSRSETGVAWGCRWEWEENGVWKENCYCEDQDGCNGTTHIDANDKDNPQ LVSEYVNDIYDYMRDLEREEVNGRMRAILIDWLVQVHVRFHLLQETLYLTVDIINRFL-- QVSRSKLQLVGVTSMLIASKYEEMYAPEIADFVYITDNAYSKSDIRRMECLILKTLDFNL GKPLPLHFLRRNSKAGEVDAMKHTLAKYFMELTIVDYDMVHHYPSQIAAAALCLSKRVLE W------------------------------TAIRSKYQSSKFMKISTLPELKSSIITDL A---------------------------------------------QRYGKDPPAAVSLG LRMEEMIFNLADSQLFFNDLEECDQVHIDDVSSDDNGQDLSNYNFQTDGFHAAATNNLCL ATGVRGGVDWMRKLAYRYRRIKEIHNSYRNNVGGLLGPQKREQWLQLRSEIEAMTDSWLT LALKSLNIINSRPNCVNVLVTTTQLVPALAKVLLYGLGGVFPIENIYSATKIGKESCFER I---------------------------------------------------MSALSVGG DRTTGQSVRTQNVMAACSIANIVKSSLGPVGLDKMLVDDIGDVTVTNDGATILQLLDVEH PAAKVLVELAELQDQEVGDGTTSVVIIAAELLKNADELVKCKIHPTSIISGYRLACKEAC KYIQEHMTINTDELGRDCIINAAKTSISSKLIGSDSDFFSNMVVDAAYAVKTADGKGGHR YPIKAVNVLKAHGKSTRESVLVHGYALNCTVAAQGMPKKVVNAKIACLDFSLQKAKMKLG VQVLVEDPEKLDAIRQRESDITKERIQKILSAGANVILTTGGIDDLCLKYFMEAGAMAVR RCKKVDLKRIAKATGGSLVLTMANLEGEETFEAAMLGQADEVVQERVCDDELILIKGPKA RTAASILLRGANDFMVDEMERSVHDALCVVKRVLESKTVVPGGGAVEAALSIYLENYATS LSSREQLAIAEFARSLLVIPKQLAVNAAQDSTDLVAKLRAYHNKSQTKADHKDLKWVGLD LYEGIVRDNKKAGVLEPAISKIKSLKFATEAAITILRIDDMIKLTPEEKQGSAYNQALRS GSLDDAAARLLVSKTILNQILVEGKDVTVEYTIFNVGNTAALDIKLTDASFPETDFDVIL GLLEIRWDRIAPSGNVSHSVILRPTKSGYFNFTSAQVTYLPSDTEPQFGYSSAPGEGGIL SFSDYDRKFSPHILDWGAFAVMTLPSLGIPFLLWYSSTSKYSTVKPKKNSGGSHKDLTEK FRSILGQVDGLRAFVEAMVNENVSLVISRQLLTDFSGHLAKLPDATSKDVSHFTLEKIQP RVISFEEQVAYIRQHLAGIYEREQSWREAASVLVGIPLETGQKQYSSDYKLETYLKIARL YLEDEDPVQAEAYINRASLLQADSQNEELQIYYKVCYARVLDYRRKFIEAAQRYNELSYK SIVAEDERMHALKNALICTVLASAGQQRSRMLATLFKDERCQQLPAYAILEKMYLDRIIR SSDLQEFSALLLQHQKALTSDGSTILDRAVIEHNLLSASKLYNNISFEELGALLEIPPAK AEKIASQMITEERMNGHIDQIVHFVHFEVREALPSWDKQIQGLCFQVNNIIEKISQHSPE WMAQAMEQQMAMKLTDLVVRSYRVAKVFRENNEKINSIDYSSNGETLISSSDDDSIVIYD CQNGTPKRTLNSKKYGVDLIHYTHAANTAVHSSTKIDDTIRYLSLHDNKYIRYFQGHTKK VVSLSMSPIDDTFLSGSLDKSIRLWDLRSSNCQGLMHLTGRPVAAFDPEGLIFAAGINSE SLKLYDLRSFDKGPFATFRLQQDKDCDWTGLKFSPDGKLILISTNGQVIRLIDAFQGAPL QTFMGHTNKGGIPLEASFSPDSQFVFCGSTDGKVHTWNTETGAKVAILASEHTSPIQCIQ FNPKYMMLASACTNMSFWLPQIDEEHLLVEKRGEKSNVGYIQLNRPKALNALCDGLMIEL AQVLDTFEEDKEIGCIVLTGSEKAFAAGADIKEMKDRKFQEVFGGNFLSHWNRLASTRKP VIAAVNGYALGGGCEIAMMCDIIYAGEKAKFGQPEIALGTIPGAGGTQRLTNAIGKSRAM EMVLTGNPIGAQEAASTGLVSKVFPVGDLVNEAIKTAEKISSQSKLVAAMAKEAVNASYE LTLQEGLRFEKRIFHATFATEDRKEGMTAFSEKRPAKFVD >Sthenelais_boa MTERKAVIKNADMSEDMQQDAVDCATQALEKFNIEKDIAAYIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSG-----REFQTSVVQRDIDQAAKYIGAGAATV GAAGSGAGIGSVFGSFVIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLILFAFM SHYKESGKAPESNIHRIRITLTSRNVKSLEKVCADLIRGAKEKQLKVKGPVRMPTKILRI TTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSKRGRGGS SGGKFRISLALPVGAVMNCADNTGAKNLYVIAVHGIKGRLNRLPAAGSGDMVMATVKKGK PELRKKVMPAVVIRQRKSIRRKDGVFIYFEDNAGVIVNNKGEMKGSAILGPVARECADLW PRIASNANSIRKGKTQKVQLGPSTVEGENVFGVAHIYASFNDTFVHVTDLSGKETIVRVT GGMKVKADRDEASPYAAMLAAQDVAERCKVLGITALHIKLRATGGNKTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRLXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEGI VTLRTRKFMTNRLLNRKQMVVDVLHPGRATVPKTEVREKLARMYKTTPDVVFAFGFQTAF GGGKTTGFALVYDSLDFAKKLEPKYRLARHGTRKQRKERKNRQKKVRGTKKAKVGAMPRV PLVCSKTYTTPRRPFEKERLDQELKLIGEYGLRNKREVWRVKYTLAKIRKAARELLTLDE KDPRRLFEGNALLRRLVRIGVLDEGKMKLDYVLGLRIEDFMERRLQTQVFKLGLAKSIHH ARVLIRQRHIRVRKQVVNIPSYVVRLDSQKHIDFSLRSPYGGGRPGRVKRKNMKKGTGAA PDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMPLAKDLLHPSIDEERRKCKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRKKAHMVRMNVLADALKSICNAEKRGKRQVLIRPCSKV IVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRMNKCGVISPR--------------- -------------------------------------MGRMHAPGKGISQSALPYRRSVP TWLKMSSEDVKEQIYKLAKKGLTPSQIGVILRDSNGVAQVRFVTGNKILRILKAKGLATD VPEDLYYLIKKAVAIRKHLERNRKDKDSKFRLILVESRIHRLARYYKSKKVLAPNWKYES STASALVAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXMSEQMTLRGTLQGHAGWVTQIATTPQRPDMILSASRDK TLIMWKLTRDTNYGIPQKALRGHGHFVSDVVMSSDGQFALSGSWDSTLRLWDLSTGTTTR RFVGHTKDVLSVAFSADNRQIVSGSRDQTIKLWNTLGVCKYTIDEGHKEWVSCVRFSPNT QNPIIVSCGWDKLVKVWNLTNCKLKTNHIGHTGYLNCVTVSPDGSLCASGGKDGQAMLWD LNEGKHLYTLDGGDIINALCFSXXRYWLCAATGHXIKXWDLEEK---------------- -----------------------------------XXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXMSDAEGDXVPSAAAATGNMDVNTALQEVLKTALIHDGLARGLREC AKALDKRQAHLCVLANNCDERNYVALVEALCAEHGINLMKVDDNKKLGEWAGLCKIDREG KARKVVGCSCVVVRDYGKETQALDVLQEYFKSKRXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMDDFQSGEETAFVVDEXS NIIKESIEGAIGGNAYQHNKVNQWTSNVVEQCLNQLTKLGKPFKYIVTCVIMQKNGAGLH TASSCFWDNTTDGSCTVRWENKTMYCIVSVFGLAIMFSASAKIIKPNGNKPDAFESSISQ ALLELEMNSDLKVPLRELYITAAKEIDVAGKKAIIIFVPAPQLRAYQKIQTRLVRELEKK FSGKHVVFIAQRRILPKPTRKTRRKSKQKRPRSRTLTAVHDAILDDLCFPAEIVGKRIRI KLDSSRLIKVHLDKNQQTTVEHKIETFSAVYKKLTGKDVNFEFPEYSL------------ ---------PAKD-DKEWVPVTKLGRLVKDIKIKSLEDIYLFSLPIKEFEIIDFFLGSAL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDFNGHIGLGVKCSKEVATAIRGAIILAKLSV IPVRRGYWGNKIGKPHTVPCKVTGKCGSVVVRLIPAPRGTGIVSAPVPRKLLTMAGIEDC YTSARGQTATLGNFAKATYAAIAQTYTYLTPDLWKETVFAKSPYQEFTDYLAKXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXX-SPSSTSVGSTVRQRKTGGSGAGAAGMWRFYTEDSPG IKVGPVPVLVMSMLFIASVFMLHIWGKYTR-XXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXX-------WHKRRKTGGRQAPIRKKRKFELGRPAANTKLGP QRVHSIRTRGGNVKYRALRLDTGNFAWGS-VCTKKTRIIDTVYNASNXELVRTKTLVKNA IVXVDATPFRQWYEAHYATPLGRKKGVKLTDAEEANLNKRSKKAQKKFDERKKTAKVEAP LXXQFGAGRLLACISSRPGQSGRCDGYVLEGXELEF-----------XXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRVRTK TVKKASRVIIEXYXTRLTLDFHTNKRICEEIAAIQSKKLRNKIAGFVTHLMKRIQXGPVR GISIKLQEEERERRDNFVPEISAIEEVDPDTKEMLKLLEFTDIHGLQVTEP----XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMRELRILKL CLNICVGESGDRLTRASKVLEQLTGQQPVTSKARYTVRSFGIKRNEKIAVHCXVRGAXAE EILEKGLKVREYELRRGNFSNTGNFGFGIQEHIDLGIKYDPSIGIYGMDFYVVLGRPGFN VPHRRKKVGNIGPKHKVNKDEAMKWFQQKYDGVILPGKXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXX--LTVEKVGEKKNVGFIQLNRPKALNALFTPLMMEL GSALDALEADEEVGCIVLTGSEKAFAAGADIKEMAPKDLQVVYKEDFIKPWTRLADTRLP VIAAVNGYALGGGCGVAMMCDIIYAGEKAQFGQPEITIGTIPGAGGTQRLTKAIGKSKTM EMVLTGNRITAQDAEKAGLVSKIFPVDQLVSETIKCAEKIASHSRLINIMCKESVNA--- ---------------------------------------- >Syllis_sp MTERKAVIKNADMSEDMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHAIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSG-----RQFQTSASRQDIDQAAKYIGAGAATV GVAGSGAGIGSVFGSLVIAYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLLLYAXM SHYKESGKAPEATIHRIRITLTSRNVKSLEKVCADLIKGAKEKSLKVKGPVRMPTKILRI TTRKTPCGEGSKTWDRYQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIAD--QVM QFVDPAKQFAKDSIRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNII V--------------------------RELAEDGYSGVEVRVTPTRTEIIILATRTQNVL GEKGRRIRELTSVVQKRFNFQEGTVELYAEKVATRGLCAIAQAESLRYKLIGGLAVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGEPINDYVDTAVRHVLLRQ GVLGIKVKIMLPWDPTGKIGPKRPLPDHVSIVEPKEEVIPQTPISEQKGGKMSKRGRGGS SGGKFRISLALPVGAVVNCADNTGGKNLYVIAVSGIKGRLNRMPAAGSGDMIVATVKKGK PELRKKVMPAVIIRQRKAIRRKDGVFIYFEDNAGVIVNNKGEMKGSAILGPVSRECADLW PRIASNATSIRKGKTQKVSLGPQVVEGENVFGVAHIFASFNDTFVHITDLSGKETLVRVT GGMKVKADRDEASPYAAMLAAQDVAERCKVLGITALHIKLRATGGNRTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRLMGKPRGLRTARKQRTHRRDQKWHDKD YKKSHLGTRWKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP RDGCLNYIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKEKKERPRSXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPGV PLVSSKTYMTPRRPFEKERLDQELKFIGEYGLRNKREVWRVKYTLAKIRKAARELLTLEE KDPKRLFEGNALLRRLVRIGVLDEGKMKLDYVLGLRLEDFLERRLQTQVFKLGLAKSIHH ARVLIRQRHIRVRKQVVNIPSYIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNMRKGQGGG GGMGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILY----------------XXETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIGEAREELCRMLSEDELRD AVLLVFANKQDLPNAMNAAEITDKLALHQLRQRNWYIQA--------------------- ---MPLAKDLLHPSVDEERRKCKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRKKQHMVHMNVLADALKSICNAEKRGKRQVLIRPCSKV IVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVALRDMEKWTTNL LPSRQFGYIVLTTSGGIMDHEEARRKHLGGKILGFFFXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXX--EVPEIKLFGKWSADEVQVSDISLTDYIAVKEKYAKFLPHSAGRYQVKRFR KAQCPIVERLTSSLMMHGRNNGKKLMATRIVKHAFEIIHLLTGENPLQVVVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREAAFRNIKTIAECLADELINAAK GSSNSYAIKKKDELERVAKSNRMTEQMTLRGTLQGHGGWVTQIATTPQYPDMILSASRDK SLIMWKLTRDTNYGVPQKALRGHGHFVSDVVMSSDGQFALSGSWDGTLRLWDLSTGTTTR QFVGHTKDVLSVAFSADNRQIVSGARDKTIKLWNTLGVCKYTIEDGHTEWVSCVRFSPNT SNPIIVSCGWDKLVKVWNLTNCKLKTNHIG------------------------------ ---------------LNALCFSPNRYWLCAATGPSIKIWDLEGKIVVDELRQEVISTGAG PPDCTCLAWSADGQTLFAGYTDNLIRVWQVSMAARXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXMSDAEGDDTPT--VGAGSMDIYTALQEVLKTALIHDGLARGVREC AKALDKRQAHLCILANNCDEPMYVRLVEALCAEHGINLMKVDDNKKLGEWAGLCKIDKEG KARKVVGCSCVVVRDYGKETQALDVLNEYFKSKRMAAIRKKLVIVGDGACGKTCLLIVFS KDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYP----------- ------------------------------------------------------------ ------AFGYLECSAKTKEGVREVFETATRAALQVKKKKKNRXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFSAGAKIVKPQGEKPDDFEASISQ ALLELEMNSDLKAQLRELYITAAKEIDVQGKKAIVIFVPVPQLKLYQKIQVRLVRELEKK FSGKHVVFIAQRRILPKPTRKTRRKNKQKRPRSRTLTAVHDCILDDLCFPAEIVGKRIRV KLDGSRLIKIHLDKTQQTTVEHKMDTFSAVYKKLTGKDVIFEFPEYILGRGGFRGGFGGR GRGRGRGRGRGKDGDKEWIPVTKLGRLVKDMKIKQLEEIYLFSLPIKEFEIIDFFL-PSL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDNNGHVGLGVKCSKEVATAIRGAIILAKLSV IPVRRGYWGNKIGKPHTVPCKVTGKCGSVVVRLIPAPRGTGIVSAPVPKKLLQMAGIDDC YTSARGQTATLGNFAKATYAAIANTYSYLTPDLWKETALSKSPYQEFTDYLAKXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXMKFNKMVSSSRRKNRKRHFTAPSHIRRKIMSSPLSKDLRQKYNVRSIPIRKDD EVQVVRGHYKSQQVGKVVQVYRKKFVIHIERIQREKANGASVHVGIHPSKIVIVKLKMDK DRKRILERKARSRDTGKHTEETIASPSSTSVGGTVRQRKTTASGAGAAGMWRFYTEDSPG IKVGPVPVLVMSLLFIASVFMLHIWGKYTR-NRKGKKKSAINETVTREYTVNLHKRIHGI GFKKRAPRAIKEIRKFAEKMMGTPDVRVDTRLNKHIWSQGIRNVPYRVRVRLARKRNEDE DSPHKLYTLVTYVPVTTFKGTQTVNVDS-------------------------------- -------------------------------------------EKDYNVLVMDLLGPSLE DLFNFCSRRFTMKTVLMLADQMIGRIEYVHNKNFIHRDIKPDNFLMGIGRHCNKVFLIDF GLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRGS LPWQGLKAATKKQKYEKISEKKMSTPVEILCKGYPAEFAMYLNYCRGLRFEEAPDYMYLR QLFRILFRTLNHQYDYVFDWTILKQKAAIT------------------------------ ---------------------VNMIKEDGQVIHFNNPKVQASLAANTFAITGHAETKQIT EMLPGILNQLGAESLANLKKLATATGDIDDDDDDVPDLVENFDEPSKGEMTRYSLDPDNP TKSAKARGSHLRVHFKNTWETAHTIKRMHLRRAVSFLKNVIGKQECVPFRRYNGGVGRCA QAKNHKATQGRWPQKSAEFLLQLLKNAESN------------------------------ ------------------------------------------------XXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXMGISRDKWHKRRKTGGRQAPLRKKRKFELGRPPAHTKLGP KRIHTVRTRGGNKKYRALRLDTGNFSWGSEAQTRKTRIIDVVYNASNNELVRTKTLVKNA IVQIDATPFRQWYEAHYASPLGRKKGVKLTEAEEAILNKRSKSTQKKYDERKKTAKVENA LDEQFSSGRVLAAISSRPGHTGRCDGYVLEGKELEFYLRKIKAKKGK------EKFQHIL RVMNTNIDGRRKVPFAMTAIKGIGRRFSHVVCKKADIDVARRAGELTEEEVEKMITIMGN PRQYKIPDWFLNRQKDVKDGKYSQVMANVLDNKLREDLERLKKIRAHRGLRHYWGLRVRG QHTKTTGRRGRTVGVSKKKGSGTESDSSEGVPELE-MAQAAGLPEELVSKAKQSRSEKKA RKAMSKLGLKQVPGVSRVTIRKSKNILFVINRPDVYKSPASDTYIVFGEAKIEDLSQQSA VRAVNQFKTDEECDETGVEAKDIELVMSQANVSRTKAVKALKNNQNDIVNAQMMGRVRTK TVKKAARVIIEKYYTRLTHDFHTNKRICEEIAIIPSKRLRNQIAGFVTHLMARIQRGPVR GISIKLQEEERERRDNYVPEVSAIEEVDPDTKEMLKMLEFNNIPGLQVTQPI---XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMRELRISKL CLNICVGESGDRLTRATKVLEQLTGQQPVTSKARYTVRSFGIKRNEKIACHCTVRGAKAE EILERGLKVKEYELRRNNFCATGHFGFGIQEHIDLGIKYDPSIGIYGMDFYVVLNRPGFG VPKKRHRKGTIGNSHRISKEESMKWFQQKYDGVILPGKMGIKFLEFVRPFCAVLPEIAKP ERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGIS PIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMVITVGQAIVYVMTGMYGDPSE IGAGVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVN TGRGTEFEGAIIALFHLLATRTDKVRGLREAFYRQNLPNLMNLLATVFVFGVVIYFQGFR VDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAAKFSGNFFVNLLG TWADVGGGGPARSYPIGGLCYYLSPPETLGHVAEDPIHAVLYIVFMLGSCAFFSKTWIEV SGSSAKDVAKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIG SGTGILLAVTIIYQYFEIFVKEQSEMGGMSTLLF-------------------------- -------------------------------------VVLKMKMQRTIVIRRDYLHYIRK YNRFEKRHKNMSVHLSPCFRDVSIGDIVTVGECRPLSKTVRFNVLKVTKGAGSKKGFSKF XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRVIRSQRKGPGS VFKSHTKHRKGAAALRPVDFAERHGYIKGVVKDIIHDPGRGAPLAKVTFRDPYRYKLKTE TFIAAEGLYTGQFVYCGKKANLQVGNILPVGTMPEGTIVCCLEEKTGDRGRLARASGNYA TVVSHNFDTKRTRVKLPSGSKKVIPSANRAMVGIVAGGGRIDKPMLKAGRAYHKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGHASTVRRDTSAGRKVGLIAARRTGRIRGTKGTV- -AKRTKKVGIVGKYGTRYGASLRKTIKKMEVTQHGKYTCPFCGKENMRRHSAGVWTCRSC RKTVAGGAYVFSTTAAATVRSAVRRLREIKEMGRRPARCYRYCKNKPYPKSRFCRGVPDP KIRIYDLGRKKARVDEFPLCVHLVSDELEQLSSEALEASRICANKYLVKHCGKDAFHLRM RPHPFHIVRINKMLSCAGADRLQTGMRGAFGKPQGTVARVRIGQPLISVRARDQHKAEVI EALRRAKFKFPGRQKIYVSRKWGFTKWDRTVYEEMRQDGRLVPDGVSVQYRPGHGPLQKW MDAQKVTKVLGRTGSQGQCTQVRVEFLDDSNRSIIRNVKGPVREGDILTLLESEREARRL RMTKGTSSFGKRHNKTHTLCRRCGGRCYHIQKKTCSRCGYPQPRMRKYNWSVKAKRRRTQ GVGRMRHLKVVYRRFRNGFREGTEPKPRRK------------------------------ ------------------------------------------------------------ ------------------------------------VYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDSQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHSNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRC GNQAAIMELDDALKYSFLQFDPAPRRGEPHVTRRTPDYFL-------------------- ------------------------------------------------------------ -----------------------------CKALRVLNSYWIGQDSTYKFFEIIMVDPFHK AIRRDPKMNWICKPVMKHREMRGLTSAGKKSRGLGKGHKFTHTIGGSRTAAWKR------ ----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXEVMAVFKLVLVGDGGVGKTTFVKRHLTGEFEKKYVATLGVEVHPLAFHTNRGVIRF NVWDTAGQEKFGGLRDGYYIQGQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCG NKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLVGDANLEFVAMPA LAPPEVTMDPDLKQRYEDELKAAQNTALPDDDDDLXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXLGFAENFALSGAAAVISKTAAAPIERVKLLVQNQDEMIKAGRLDKPYKGVIDCTV RTFRTEGVLPFWRGNLANCLRYFPTQALNFAFKDKIKAVFQMKKTDSYGTKFAKNIASGG LAGAMSLCFVYSLDYARTRLANDAKSGAKRQFNGLIDVYRKTLKSDGVVGLYRGFVISCV GIIVYRGCYFGFYDTLKPIVLGENAGVVLSFALGYVVTISAGLVSYPIDTIRRRMMMTSG EAVKYKGSWDCAMQIMKTEGFMSMMKGAGANILRGVAGAGVLAGFDKFKEVYIRYR-XXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMQNEAGETVDM YIPRKCSASNRIIHAKDHASIQLNIAEVDEATGRMTGQYKTYAICGGI------------ ----------MARGPKKHLKRLNAPKHWMLDKLGGVFAPRPSTGPHKLRECLPLMVFLRN RLKYALTYDECKKILNQRLVKVDGKVRTDNTYPAGFMDVVSLEKTGENFRFIYDVKGRFA VHRIQPEEAKYKLCKVKRVSVGPKGVPYINTHDARTIRYPDPLIKVNDTVQVXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------EIQRTMLELLNQLDGFDSKGDVKVVMATNRIETLDXX XXXXGRIDRKIEFPLPDEKTKRRIFNIHTARMTLADDVNIDDYIMAKDDLS--------- ------------------------------------------------------------ ----VNWARKSSLWPLTFGLACCAVEMMHFAAPRYDMDRFGVVFRASPRQADCIIVAGKV TKK----------XXXXXRWVISMGSCANGGGYYHYSYSVLRGCDRVIPVDIYVPGFPPS AEALLYG--------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMVATKKGKK TIESINSRLALVMKSGKYVLGYNQTLKTLRQGKAKLVIIANNTPPLRKSEIEYYAMLAKT GVHHYNGNNIELGTACGKYFHVTTLSITDPGDSDIIRNMPSGXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKVELCS FSGFKIYPGHGKKMVKADGRAFQFINAKCEKSHLMKRNPRKIDWTVLYRRKHKKGQTEEV TKKRTKRTTKFHRAITGATLTDIMAKRNQKPEVRKAQREQAIRAAKEKARAKATAKPRVG GKR--------------------------------------------------------- ------------------------------------------------------------ -------------------------------------------------KAPKIQRLITP LTLQRKRHKLLMKKRRAAKKRDEAADYAKLLAQRLKEAKERKLERRRSASQSKKVKAKEL RGKKKEELLKQLDELKTELSQLRVAKVTGGAASKLSKIRIVRKSIARVLTVIHQTQKENL RKFYKPTDLRRKKTRAMRRQLTKHERSIKSAKQLRRERVYPMRKFAVK------------ -----IGGEKAGRIVIGLFGKTVPKTVKNFKQLAEGEDSYKGSKFHRVIKDFMIQGGDFT KGDGTGGRSIYFEDENFKLKHYGAGWLSMANAGKNTNGSQFFITVKKTEWLDGRHVVFGK VLEGMDVVRKIENTKTDRDKPAADVVIADSGSIPVEEPFSVEKSGAQ-KKKKTVLKFAVD CTHPVEDGIMDCANFEKFLHERIKVQGKTNNFKSKVVISADIPFSKRYLKYLTKKYLKKN NLRDWLRVVSNAKESYELRYFQINNEDEEEEGD-TKDDKGDEEKVYGGCEGPDAMYVKLV SSDGHEFIVKREHALTSGTIKAMLSGPGQFSENETNEINFREIPSHVLQKVCMYFTYKVR YTNSSTEIPEFPISPEIALELLMAANFLDCXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------VGDVLVLTKPLGTQVAVNAYQWLDQPERWNRIKLVVSEDDVRKAYQRAMFSMAR LNRTAARLMHKYNAHGATDVTGFGLLGHATNLARVQKNEVGFVIHNLPIIAKMAAVSK-- ------------------------------------------------------------ ------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXX----------------VGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLV TMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTMPNTFKTLDSWRDEFLIQASPRDPEN FPFVVIGNKIDLENRAVSTKRAQSWCHSKGDIPYFETSAKEAINVEQAFQTVAKNALAQE TDVDMYNDFPDQIKL-----------TPGFDARFPNQNQTRNCWQNYVDYHRCHKVDDYE PCEYFKWVYKNMCPRFWYEHWDEQME--------XXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---EKTHINIVVI GHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITI DIALWKFETAKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKNGQT REHALLAFTLGVKQMIIGVNKMDSTEPKYSEARFNEIKKEVSSYIKKIGYNPDAVPFVPI SGWHGDNMLNMTWFKGWEVVEGKTLLDALDQIDPPKRPTDKPLRLPLQDVYKIGGIGTVP VGRVETGILKPGMVVTFAPPNVTTEVKSVEMHHQALDEANPGDNVGFNIKNVSVKDIRRG NVCGDSKNDPPKGADTFLAQVIILNHPGQISAGYAPVLDCHTAHIACKFVELQEKIDRRS GKKLEDKPQNVKSGDAAMVDMKPQKPMCVEAFSDYAPLGRFAVRDMRQTVAVGVIKSVNK KEATGGKVTKAAQKA--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------FVSGACDASAKLWDIRDGMCKQTFSGHES DINAITFFPSGFAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLG GYDDFNCNVWDTLKQDRAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKIWNXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPKQ IMEIKDFLLTARRKDAKSVKIKKNVKFKVRCSRYLYTLVIQDREKAEKLKQSLPPGLAVK ELKMSKINRELLRESVANVLQKKRKFTETVELQIALKNYDPQKDKRFSGTVKLKHIPRPK MTVCVLGDQQHCDEAQANNMPCMDVEALKKLNKNKKQVKKLAKRYHAFLASDSLIKQLPR ILGPGLNKAGKFPTMLTHNESMPQKADEVKQTIKFQMKKVLCLAVAIGNVTMDQDQLVSN ITLSVNFLVSLLKKNWQNVRALYIKSTMGPAQRIYXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXMTDNNILNFADPFLATVDIHIRIQQRNGRKTLTTVQGIHADYDLKKI VKACKKEFACNGTVVDHPEYGEVIQLQGDQRNSIKGFLMKCKLEEQIKVHGFXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------RQTGKTAVAIDTIINQKRFNDGTDEKKKLYCVYVAIGQ KRSTVAQIVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCAMGEYFRDNGKHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDNFGGGSLTALPVIE TQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQQKAMKQVAG SMKLELAQYREVAAFAQFGSDLDAATQQLLNRGVRLTELLKQGQYVPMPVEEQVAVIYSG VRGHLDKLDPAKITQFEKEFLAHIQVSHRDLLNAIAADGMISEANEAKLKEITTSFVAGF XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPILIDARGHLLG RLASIVAKCILNGQRIVVLRCEGINISGSFYRNKLKYMEFLRKRMNTNPSRGPYHFRAPS KIFWRTVRGMLPHKLHRGKEAMDRLKCFEGIPSPYDRQKRMVIPAALKVLRLKPLRRYCT LGRLSHEVGWKYQNVVATLEAKRKVKSSRFHNKKQLEEKLRAKAKKTGEAQKVIESYG-G GICERTKKRFIQRCCQCH------------------------------------------ -------------------------------------------XXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- ------------------------------------------------------------ ---------------------------------------------------KLMDLDTEH LGIPETDYSCVVKLP-AXXXXICRDLSQIGESVVICCTKEGVKFSASGDLGTGNIKLAQS ANVDKEDEAVTVEMQEAVTLTFALQYLNFFTKATPLSPRVSLSMSPDVPLVVEYKIAEMG YIRYYLA---------KALAAYHTSKNSAKGRVVAVIGAVVDVQFDEGLPPILNALEVSN RSPRLVLEVAQHLGENTVRTIAMDGTEGLVRGQVCVDTGTPISIPVGPETLGRIINVIGE PIDERGPVESKEHFGIHQEAPEFVEMSVEQEILETGIKVVDLLAPYAKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVIDLKGKGSKVSLVYG QMN--XXXXXRVALTGLTVAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQE---------------------------------------------- ----YPAVDPLDSTSRILDPNIVGHEHYNIARGVQKILQDYKSLQDIIAILGMDDLSEDD KLTVSRARKIQRFLSQPFQVAEVFTGSAGKLVPLKDSIKGFKMILDGELDNLPEVAFYMV GPIEEVTQKAERLAEER------------------------------------------- ---------------------------------RDFLHLPPEIVPATLKRQPMGEDRAAY RRGAGGDKKADAGAGATXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -MSAHLQWMILRNNSSFLLKGNTFSREPNNLKNKNSFRFNGLVHKKTLGVEPASDGKGVV IVTKRNFRKPSKSYSRVELKRDSRRTLSSIRKTIGKSGYRKDLNMAALRRASAILKSQKP VVVKKTRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXX----------------------------------------------------- ------------------------------------------------------------ -------------------------------------RSYGMPEIDDDELEAELDALGDD LALDEDSSYLDQ-VGAPSAPTSVPGEDSVTNKDGVPVDEFGLPQIPAQXXXXXXXXXXXX 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------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------RDDELAREQQRQEENDVLRKQFAQAANAFH QWLTDTRSAMMEGTGTLESQLEATKRKSAEVRAQRTQLKRIEDLGAAMEERLILDNRYTE HSTVGLAQQWDQLDQLGMRMQHNLEQQIQACNTSGVSEEALREFSMMFKHFDKDKSGRLD HHEFKSCLRALGYDLPMVEEGQRDPEFEAILDSVDPNRDGMVSLQEYMAF---------- ------------------------------------------------------------ ---------------DSNEDASCPSNRGFDEELNAMIDCNSLEAHTPGTFCMKITQQSPG WRGWKKVTRRCGSRSDTGVAWGCRWDFEENGVWKEVCYCEDKDGCNSSTT---------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------AKYLMEVTIVDYDMCHIHPSTIAAAALCMSIKLLD WNDTLSHYSKYQESELLPVMQKMAALVTRKLTAIKTKYSSSKFMKISNIPELQS------ -XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- -----------------------------------EVAYFPKEDETQFGYTSAPGEGGIM NFRDYDRKFSPHVLDWAAFAVMTLPSLGIPFLLWYSSKSKYDTTKAKKSXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXX------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------SKLIVMMAKEAVQKSYE MTLQEGLIFEKRFFHQTFGTKDRQEGMTAFVEKRPANFTN >Symbion_pandora XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------LHTSSSMKDIDQAAKYIGAGAATV GVGGSGVGIGSIFGNLIIGYARNPGMKQQLFSYAILGFAMSEAMGLFCLMMAFLILYAF- ------GKAPDQAAHQIRITLTSCNMKNLEAVCSELIRGAKDKKLKVKGPVRMPTKTLRI TCRKTPCGEGSKTWDRFQMRIHKRVIDLHSSKQIVKDITSISIEPGVEVEITIADMDYIT QAVEPVKHFAKDSYRLVKRCTKPDAKEYKKIATATAIGFSIMGFIGFFVKLIHIPINNII VMPRLVSKKKKFVADGVFKAELNDFLMRELAEDGYSGVEVRVNLTKTDIIILATRTQNVL GEKGRRIRELAFLVQRRFGFPEHSVELYADKVAQRGLCAIAQAESLRYKLIGGLPVRRAC YGVVRFIMESGAKGCEVVVSGKLRGQRAKSMKFGDGLMIHSGHPVNEYIDEAVRHILMRQ GVLGIKVKIMLPHDASGKIGPKKCLPDTVSIVEPKEDTVYDEPFTESKAADMPKRGRGGA CGGKFRIALGLPVGAVMNCADNTGAKNLYVIAVFGIGACLNRLPSACVGDQFVAAVKKGK PELRKKVMQAVVVRQRKCYKRKDGTFIYFEDNAGVIVNNKGEMKGSAVTGPVAKECADLW PKIASHAASIRKGKVVAVVLGPQVEEGVLVFGVAHIYASFNDTFVHVTDLSGRETIVRVT GGMKVKADRDESSPYAAMLAAQDVAEQCKTRGITALHIKIRATGGNKTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDTTRRKSGRRGRRLMGKPKGLRTARKLRNHRRVNKWADND YKKAHLGTRWKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP NDGCLNCIEENDEVLIAGFGRKGHAVGDIPGVRFKVVKVAGVSLLALFKGKKERPR-ADS ATIRTRKFLTNRLLCRKQMIVDILHPGRASLPKLEIREKLAKMYKTTSDTVFCFGFRTQF GGGKSTGFALIYDTLDLAKKMEPKYRLLRHGTRKQRKERKNRQKKVRGVKKASV------ ------TFSTPLRPFEKERLDQELRLIGQFGLRNKREVWRVKFALSKIRKTARILLTLDE KDPRRLFEGNALLRRLVRIGVLDETKMKLDYVLGLKIEDFLERRLQTQVFKLTLAKSIHH ARVLIRQRHIRVRKQVVNIPSFVVRLDSSGHIDYSLKSPYGGGRPGRVKRKKLRKADAG- --XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMPLAKELLHPTYEEEKRKHKFKRLLQSPNSYFMDVKCPGCYKITTVFSHSQTVVVCT ECTAILCWPTGGKCSLKEGCSFRKK--MVRMNVLADALTSICNAEKRGKRQVLIRPSSKV IVKFLTVMMKHGYIGEFEIVDDHRGGKIVVNLTGRLNKCGVISPRFDVKIPHVERWTTTL LPSRQFGYLVLTTSGGIMDHEQARRKHLGGKILGYFFMGRMHTPGKGYSGSALPYRRSVP SWLKLSSEDIIEQICRLSKKGLLPSQIGVILRDSHGVAQSRFITNSKILRVLKSQGIRPS IPEDLYHLIKRAVQIRKHLDKHRKDRDSKFRLILIESRIHRLARYYKKTRVLPPTWKYQS ATASALVSIVELPEVKLFGKWSTEDVSVGDISLADYIAVREKHSKYLPHSAGRYQVKRFR KAQCPIVERLVSSLMMHGRNNGKKIMTMRIVNHTFDIIHLLTGENPLQILVTAIINSGPC EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGARDAAFRNIKTIAECLADELINASK GSSNSYAIKKKDELERVAKSNRMAEQLTLRGTLAGHNGWVTQIATTPQFPDVLLSASRDK SLILWSLTRDINYGTPRQRLKGHGHFVSDVVISNDGQYALSGSWDNDLRLWDLNAGKSAT RFVGHTKDVLSVAFSPDNRQIVSGSRDKTIKLWNTRGKCKYTVDDCHSEWVSCVRFSPNI TNPSFVSCGWDKVIKVWNLADCRLMFNHHGHSGYINTVAVSPDGSLCASGGKDGNAMLWE LSDGHHLYTLKGNEVINTLCFSPNRYWLCAAVGSSIKIWDLEGKKVLDELKCEAVGTGGP KAECISLAWSADGQTLFAGYTDNVIRVWQVSMAARXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXMAEEKK-SDDHINLKVTGQDGSVVHFKIKKNTALRKLMN AYCDRAGVKMSVVRFMWDGQNIGESDTPAQLEMEDNDVIEVFQQQTGGMSALPINPKPFL NGMTGKVVCVKLKWGMEYKGILVAVDAYMTLQLAETEEYIDGAFSGNLGEVLIRCNNVLY IRGADEED-------MSELEGD-VSV--APVATMDVNTALQEVLKNALAVNGLARGLNEC CQALDRREAHLCVLSSSCDEPSYVKLIEALCSHHGIKLMKVENNKVLGQWAGLCKIDKEG NARKVVGCSVVVVQS-TQSCQEWDVLQQYLNSQ-XXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--DEQNAEELTFQVDEIT SIVKDAVEATLGGASYQHNKINQWTSNVVEQCLVHFSKLAKPFKYIVTCVIMQKNGAGLH TATSCYWDSTNDASCTVRWENKGMYCVVNVFGLAIMFSSTVKILKPEGEKPSDVEVRVSQ AILDLQMNSDLKAQLQELSITKVKEIAVTGRKIYLVYVPPPQLTKFQKVQTRLVRELEKK FTGIHVIFVADRRILPKPNRKSIRKIKQKRPRSRTLTAVHDAWLQDIVFPAEIVGKRTRM KLDGSRLIKVHLDKSDQTNVEHKVDTFVATYKKMTGKDVIFEFPEWVL----FRGGFGGR GRGRGRGRGRRGKDDKDWVPLTKLGRLVKDGKIKQIEDIYLFSLPIKEAEIIDFFLGPNL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDSNGHVGLGVKCSKEVATAIRGAIILAKLSI IPVRRGYWGNKLGKPHTVPCKVTGKCGSVIVRLIPAPRGTGITAAAVVKKLITMAGISDI YTSASGCTATMGNFAKAAYAAMKMTYYYLTPDLWSETEYKPDIYHDFSKYIQ-MSGGLEC LNLVDNDVSKFLAASTHLGAANADYQMQTYVFKRKNEGTHIINLRRTWEKLLLAARAIVA IENPADVCAISARQFGQRAVLKFASYTGATAIAGRFTPGTFTNQIQAAFKEPRLLIVTDP RTDHQPICEASYVNIPVIAFCNTDSPLRYVDIAIPCNNKGRTSIGLMWWMLCREVLRLKG NIPR-TEWDVMPDLFFYRDAEEIEKE---------------------------------- -------MKFNKLVTSSRRKNRKRHFQAPSHIRRKIMSSPLSKELRQKHNVRSMPVRKDD EVQIVRGHYKGQQVGKIIEVYRKKFVIHIERIQREKANGVTAHVGIHPSKVVIVKLKLDN DRRRILERKASSRKDGKHTEESVAPASATSVGGGLRQRKSVGSPSNNAGMFKFYSEDSPG IKVGPVPVLVMSLIFIASVFVLHIWGKYNR-KKAAKSKPKVKEVVKRDYTINLHRRIHGI TFKKRAPRALKEIKKFAALAMGTPDVRIDTKLNKYIWSRGIRGVPFKVRVRLHRMRSNDA DSIHQMYTHVGHVVVTSFKELHTVDIPIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNVEKLKMRIGGKGTARRKRKVLHRTATTD DKKLVTCLKKLSVNNITGIEEVNMIKDDGTVIHFNNPKVQGSPASSIYAITGQGEIKQVT EMLPGILTQLGAENVSSLKQFAAGVDTIEEADEEAFELDGDFDEVAKVEMGRYASEPEVS SKSAKARGSQLRVHFKNTHEVAQAIKHMKLSRATKYLKNVMIKQEIVPFRKFAGKVGRHS QAKQFGCSKGRWPTKSCRFILDILKNAQSNAVFKGLEVERLYIEHIQVNAAVKSRRRTYR AHGRINGYVCSPSHIEVILTERDDIVKAPEKKKISQKKLKRQMLKNREXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXMGISRDKWHKRRPTGGRRPQPRKKRRYELGRPAANTKIGS KRVHRVRARGGNIKLRALRLDTGNYGWASEGVSRQTRVIDVVYNASNNELVRTKTLVKSC IVQIDATPFRQWYESHYAKPLGKTKVTKAV--AEAEMLDKTKKVLKKFANRSKTAGVETA LSDQFNSGRLLARLTSRPGQVGRADGVILEGRELEFYLRKLKTKKNRMSLVAPEKFQHIL RVMSTNIDGRVKVPYAMTKVKGVGRRFSSLVLHKAGIDMKKRAGELTDEEVEAICVIINN PRQYKIPDWFLNRQKDIKDGKYSQVVSNALDNKLREDMERLKKIRAHRGLRYYWGLRVRG QRTKNTGRRGRTVGVSKKKDSDSSEEDSDNVPELENFSKAAGLPDEVISKAKQTKGEKKA RKAISKLGLKPVTGVNRVAIRKAKNLFFVINRPDVFKSPASDTYIVFGDAKIEDLNQQAQ ISAAEKFRNDEEIDETGIAEKDIEVVIGQASVSRAKAVKALKQNDNDIVNAIMMSRVRTK TIKKASRVIIEKYYTRLTLDFHTNKRICEEIALIPSKSLKNKIAGFVTHLMKRIQKGPVR GISIKLQEEERERRDNYVPKVSALDEIDAETKQMLEMLNCGSIPT----------XXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMRELNIKKL CLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTIRSFGIRRNEKISVHCTVRGPKAD EILEKGLKVKEYELRKGNFSHMGNFGFGIQEHIDLGLKYDPSIGIYGMDFYVVLGRKGER VSKRRRKNNHVGFSHRMTRDDALKWFQQKYDGIVLPGKMGVKVLEFVKPFCALLPEVSKP ERKIQFREKVLWTAITLLIFLVCCQIPLFGIMSSESADPFYWVRVIMASNRGTLMELGIS PVVTSSLIMQLLAGAKILDVGDTPKDRALFNGAQKLFGMVITIGQAIVYVMTGMYGVPSE MGLGVCLLIVIQLFVAGLIILLLDELLQKGYGLGSGISPFIATNVCETIVWKALSPTTVN TGRGTEFEGALIALFHLLATRTDKVRGLREAFYRQNLPNLMNLFSTVLVFAVVVYFQGFR VDIPIKSARHRGQQSSYPIKLFYTSNIPIILQS--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------QNEKSYQKQPTIFQNKKSVLLPRYTR NVGLGFKTPREATEGTYIDKKCPFTGDVSIRGRILTGVVSKMKMQRTIVIRRDYLHFVKK YKRFEKRHRNISAHLSPCFRDIEIGDVVTVGECRPLSKTVRFNVLKVNKFSKSKKGFQK- XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRVIRAQRKGAGG IFKSHTKNRKGAAALRPVDYAEKHGYIRGVVKDIIHDPGRGAPLAKVVFRDPYRYKRVTQ TFVACEGMYTGQFVHCGKKAMLTIGNVLPVGSMPEGTIVCCLEEKMGDRGKVARASGNYA TIVAHNPDTNRTRVKLPSGQKKLIPSFNRAMIGIVAGGGRIDKPLLKAGRAYHKYKAKRN SWPKVRGVAMNPVEHPFGGGNHQHIGKASTVRRDAPAGRKVGLIAARRTGRIRGT----- -ARRTKKVGIVGKYGTRYGASLRKTVKRMEISQHAKYTCTFCGKERMKRKAVGIWECKSC KRILAGGAWVPSTVAAVTVRSAVRRLRETKEMGRRPARCYRYCKNKPYPKSRFCRGVPDP KIRIFDLGRKKADVEEFPLCIHLCSDEYEQLSSEALEAGRICANKYMVKYCGKDAFHLRV RVHPFHVLRINKMLSCAGADRLQTGMRGAFGKPHGTCARVNIGQVIMSIRTKDSNKAHAV EALRRAKFKYPGRQKIYISNKFGFTKFKREDFAELMAEGTIIPDGVGVQYKPKHGALAKW KA--RVIKILGRTGSQGQCTQVRVEFLGDSNRSIIRNVKGPVREGDILTLLESEREARRL RMTKGTSSFGKRHNKTHTLCRRCGKSSYHIQKKTCAACGYPSKRIRKYNWSEKAIRRKTT GTGRMRHLKTVRRRFRNGFREGGLAK----LIDDKTSVKELDQWIERLYQCKQIEEGQVK TLCAKAKEILTPESNVQGVRAPVTVCGDVHGQFHDLIELFKIGGDAPDTNYLFMGDYVDR GYHSVETVTLLVALKVRFKNRVTILRGNHESRQITQVYGFYDECLRKYGNANVWKYLTDL FDYFPLTAIVEGQIFCLHGGLSPSIDRLDGICALDRVQEVPHEGPMCDLLWSDPDDCDSW GISPRGAGYTFGKKISDTFNHTNNLTLIARAHQLVMEGYNWCHDRNVVTIFSAPNYCYRC GNQAAIMELDESLKYSFLQFDPAPRSNEPXTTRRRPDYFLXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-DGLSSYYQSKIEEYQLVVSERMQN LRRLEAQRNELNAKVRMLREELQQLQEQGSYVGEVVKAMDKKKVLVKVHPEGKFMVDVDK NINIADITPNCRVALKNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDRQIKEI KEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ KFIGEGSRTVRELFVMAREHAPSIIFMGEIDSIGSSRLXGSSGGDSDVQRTMLELLNQLD GFEPKQNI---------------------------------------------------- ------------------------------------------------------------ -----LGFAENFALSGAAAVISKTAAAPIERVKLLVQNQDEMIKAGRLDKPYKGVIDCTV RTFQSEGLVPFWRGNLANCLRYFPTQALNFAFKDKIKQIFNQKKSDPYMINFGKNIASGG AAGAMSLCFVYSLDYARTRLANDAKSGK-RQFSGLVDVYRKTLKSDGFVGLYRGFFISCF GIIVYRGCYFGFYDTLKPIVLGDNASMLLSFMLGYIVTISAGLLSYPVDTIRRRMMMTSG QAVKYKGSVDCAVQIIKSEGFMSLMKGAGANVLRGVAXAGVLAGFDKFXALYLKWRLXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMQSDVGELVDM YVPRKCAASSKIIGARDHASVQLNFAEVDE-SGYMTGVLRTYAVCGDIRRMGESDDSILR LVKRDGLV---VRGRRKHLKRLNAPKHWMLDKLGGNMAPRPSCGPHKLRECLPMVILIRN RLKYALTYQETKKVTYQRLVKVDGKVRTDIRYPLGFMDVVSIEKTGENFRLIYDVKGRFT IHRISTEEAKYKLCKVRKTLTGPKGVPYIVTHDGRTMRYPDPLVKVNDTIQVXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------RRMKVTSNDFRKAKDNVLYRKNDGMPEGLYLXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----KKTKK SSEGINTRLSLVMKSGKSVLGYKQTKKMLRSGKAKLIIIASNTPPLRRSEIEYYAMLSKT GVHHYNGTNIDLGTACGKYFRVATLAITDPGDSDIVKTYEKNXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKTEVCY YSGMKIYPGHGRRAVKIDGRVFHFLNGKCERSFNLKKNPREVKWTILYRRKHKKGIMEEE KKKRSKRTVKTQRAFAGATISDILTKRNQKPEVRQALREQAIRSAKDKQKQKNTQAPRVG GKRMKFNIAYPATGSQKVIEIDDEKKVRPFYEKRIASEVEASCLGAEWEGYVLKVTGGND KQGFPMKQGVLTNSRVRLLLTKSR---RILKDGERRRKSVRGCIIDSNLSVINAIIVKKG IQEIPGLTDKTVPRRLGPKRASNIRKLFNLSKQDDVRKYVVRRPCPPRSKAPKIQRLITP VVLQRKRRRIALRRKQFARSREDAAAYHKLLQQRLKEAREKKLERRRSQSQSRKVKAKAI RNKTKDELETMLSNLKKEFLSLRVQKATGSGTNRSNNILKIRKSIARVLTVLNQTQKENV RKFYKPKDIRRKKTRAIRRALTPKEQSIKSSKQQRKERLYGLRMFALKSAAKGPKVTDKV FFDIEIGGESAGRIVIGLFGKTVPKTAMNFKTLAEGSATYKGSKFHRVIKDFMIQGGDFT RGDGTGGKSIFFPDENFKLKHFGAGWLSMANAGKDTNGSQFFITTKKTEWLDGRHVVFGK ILEGMKVVRKIEATKTDRDKPEKDVVIADSGSIPVDKPFATAKEPSKE----------LD CTHPAEDRVMDIPILEKFLQDKIKVNGKTGQLKTKIIVTADQDFSKRYLKYLTRKFLKKY LLRDWLRVVATSKDAYELRYFQISDNLEEE----XXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSKTFTLSEVETHNASDSIWLVIHDKVYDVT NFADEHPGGEEVLIEQGGTDATTAFEDIAHSSDARDIMHKYYIGDICESDRDKISGYIVP IIIAVFAGLGFRYLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGREKIHINIVVI GHVDSGKSTTTGHLIYKCGGIDKRVIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITI DIALWKFETAKFYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQT REHALLAYTLGVKQMIVGVNKMDSTEPPFSEDRYNEIKKEVSAYIKKVGYNPDAVAMIPI SGWHGDNMLKMGWWKGFTIVNGKTLLDALDTIMPPSRPTDKPLRLPLQDVYKIGGIGTVP VGRVETGIIKPGMVITFAPANITTEVKSVEMHHESLDEAVPGDNVGFNVKNVSVKKIRRG XVAGESKNDPPR------------------------------------------------ ------------------------------------------------------------ ---------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXX-----IELGDITAHNVKQFKCLNSVIFPVSYNDKFYKDVL KLGELAKFIYFNGCVVGAVCCRTDTTNNRRRLYIMTLGCLFAYRRCGLGRRMLEHILKIA EKDGGYESVYLHVQVNNEGAIQFYEKFGFKVKEKKENYYQRIEPADAYVVELSLKEMPKE LKEIKEFLIHTRRPDAKSIKIKKNVKFKLRCSRFLYTFVINESDKVDKLKQSIPPAVIVK ELK-SKISKDALYEAIASVLQKKRKFVETVELQVALKNYDPQKDKRFSGTVKLRHIPKPK YRVCVLGDQQHCDQAAANKIPFEDVDSLKRLNKDKRLVKKLAKSYDAFMASDSILKQIPK LLGPGLSKAGKFPSRLTHSDSMMGKIDDIKATIKFQMKKVLCISVAIGHVGMTSEQLYQN ITLSINFLVSLLKKNWQNVRVLTIKSTMGPPQRIYMALADKINIDSIIQKLLGVKGGRPG KIVQLDDSEITALCLKSREIFLSQPILLELEAPLKICGDIHGQYFDLLRLFEYGGFPPES NYLFLGDYVDRGKQSLETICLLLAYKIKFPENFFLLRGNHECASINRIYGFYEXCKKRHT VKLWKTFTDCFNCLPIAAVVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKETPGWGENDRGVSYTFGAEVVGKFLHKHDLDLICRAHQXVEDGYEFFSKRQLVT LFSAPXYGGEFDNAGAMMSVDETLMCAFQVLKP--------------------------- ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXX---SSIQNLKDPFQDDNIVHIRIQQRNCRKTLTTVQGINQAFDLKRI IRACKKEFACNGTVVEHPEYGEVIQFQGDQRKKIAEWLVRNQVAELIKEHGFXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXTSRVGSLVGRVANQGIKKHSTGPCANILLNKFSASAEVSSILEERILGAPSTNLEET GKVLSVGDGIARVYGLKNIQAEEMVEFSCGIKGMALNLEADNVGVVVFGNDRMIKEGDIV KRTGAIVDVPVGEGMLGRVVDALGNAIDGKGPLNVTKRQRVGVKAPGIIPRTSVKEPMLT GIKAVDSLVPIGRGQRELIIGDRQTGKTAIAIDTIINQKRFNEAADEKQKLYCIYVAIGQ KRSTVAQLV-RLTDADAMKYTIVVSATASDAAPLQYLVPYSGWAM--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MEILYSIPFKFLEVPNLRITKPSWVRRPESMTVFGFILISYFLVTAGVIYDVIVEPPSIG STTDENGNSRPVTFLPYRVNGQYIMEGLTASFMFSLGGLGFIILDQTNGKYTPKLTRILL LMLGFVCVLISFFATRLFMWIKMPMPKVKRSRKPPPDGWELIEPTLEELDGKMREAETEP HEGKRKVESLWPIFKLHHQRSRYIFDLFYRRKAVSRELYNYCLKEGIADGNLIAKWKKQG YENLCCLRCIQARDTNFGTNCICRVPKAKLEESKIVECVHCGCRGCSGXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXX-------------------GTQVNGAITGVNVSM NTHLSKVKMTMKNLEPVXLEPLTINPPNIRYYILPYSLPLDSLLVDDGPKSRPGKXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPIVIDARGHLLG RLAALVAKTLLQGQRVVVVRCEEINISGSLYRNKLKYLDYLRKRMNTKPSKGPYHFRAPS KMLWRTIRGMLPHKLFRGKEALDKLKVFDGIPSPYDKKKRMVVPSALRTLRLNPRRKYCT LSRLAHEVGWKYRGVIETLEARRKVRAEDWYKKKRQEKKLRARAIRIEPQQKFIESCG-X XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIEVERTLALIKPDIAAA EIEDIILHAGFTILQKRRILLSPEQATDFYAEHFGKLFYPSLIAYMSSGPVVALSLARHN AIKHWRELIGPTNPNIARQNAPDSLRAKYGENETMNGFHGSDSPASAEREIRFFFPDAIV EPIVRKQAARDYLARNVNATLLKGLTQICKEKPANPVVALADWLIENNPNKPKIEXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXX-----------TPRGKVVSVIGAVVDVQFDNELPPILNGLEVEN RSPRLILEVAQHLGENTVRTIAMDGTEGLVRGNVCVDMGSSISIPVGPATLGRIINVIGE PIDERGPIQTDLRAPIHAEAPPFVEMSVTQEVLATGIKVVDLLAPYAKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVISLKDDSSKVALVYG QMNEPPGARARVALTGLTVAEHFRDKEGQDVLLL-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------MLMPKKNRNAILEHLFNEGVLVAKKDFFLQKHPDIKVPNLHVI KVMQGLKSKGLVKEQFAWRHYYWSVNNDGIQYLREYLHCSADVQPATLKRPDGTTERGDY RKAMGGEKEAPAGAGS-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX MTNPKGIRRGTRYMFSRSFRKHGLIPLSTYMKPYRRGDIVDIKGNGAVQKGMPFKDYHGK TGRIYNVTQHSIGIIVNKRVRGRIIPKRINVRVEHIHPSKCRTDFLKRVKENEAKKKEAK LSITCKRLPVQPVGAHFVRTKTNKPIVLQPIPYEFVA-----YKYISEPSENDGWKELTD KAATSFFMKEIISGLSLTMGHMFKEPATINYPFEKGSLSPRFRGEHCLRRYPSGEERCIA CKLCEAICPAQAITIEAEEREDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEY STESREELLYNKEKLLHNGDIWETEIAANIEADHLYR------------------DEKQE EALRNIDNVQNEIDDLNQQVSDEILKLEQKYSKLREPLYAKREPYIAKIPNFWSTTFSNH PQISILMSRTDEEIFQFLDKVDIEEAEDIKNGFKIHFHFKVNPYFENLKLTKEYSMATTM AVEIKWKPNMDPTKKNNKRRPD-DFSIISWLVDKSDA-SEEIVEIIKDDIWPNPLQYYMA ADATEYSE-DDDVDDGE-KLTSEEEFLLQNFSRQVSTKSSALFYGNAFIVSSLPIWLYWR IQETAVDITLSIITAIAAFLISFAYVNTKHLFKHKFAVKREEEVARQLTKQFANDKKMAK KDKDERILWKQNDVADYEATTFSIFYNNSIFLFIVIVLTFWIFKSFNPLLGYSLTMLLSA GLVALFSTGTK--------YNVVLLGDSHVGKTSLLRCFTQEPCVDKLLPTLVADYVRHT FTYDGLRIKLHVWDSPGKERFRTLTKRQLTGINGIVIVFDLTKNETFLNVDSWIDTIHKE NSAQIPLTLAXNKAEMREVSFGEAKEYSEKHLMM-------------------------- ----------MAEYLASIFGTEKDKVNCSFYFKIGACRHGDKCSRLHNKPTFSQTVMMHN LYINPGNLALVNLDEQEEQLHYEEFFEEVFLECQEKYGKVEEMHVCDNLGDHLVGNTYVK FQREEDAERAMNELNDRWFNGRPIMAELSPVTDFRESCCRQYEMGECTRGGFCNFMHLKP ISRELRRKLYSKKRRSRSRSRERKRSKSRE----RRKSRDRKDRRXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXMLVLVIGDLHIPHRVSGLSPKFRKLLVPGKIQHILCTGNLCTKDT YDYFKNLAPDVHVVRGDFDDNINYPEMKVVTVGQFKIGPCHGHQIVPWGDVESLAMLQRQ LDADILITGHTHRFEIYEHQGKFFINPGSATGAYHPLNSEVTPSFILLDIQKNNIVSYIY QLVENEVKVERMEFKKMVKFLQPGKVVLVLGGRYAGKKGVIVKSYEEGKEDRPYGHALIA GIVRYPRKVTKRMGKKKIKERSKVKTFLKVYNYNHLMPTRYLFFDVNHQVVNKEAAKDPS KRKKACRFVKSMFENTYKAGDNKWFFQKLRFXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-- -----------KDKALKAKKHVKQGSQGIAKRKIRTSVHFRRPKVLHLRRTPKYPRRSTI KRTVLDEFRIIKFPLTTESAMKKIEDNNTLVFIVDKRSNKPQIKKAVKFLCDFEAARINT LIRPDGEKKAYVKVPPALDALDVASKIGIIMPTTQRMRMANEKANKNIHIRGNVPKTLKE NEEKYAVGPWLLALFIFVVIGSAVFQIIQAVRFXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMIRFL LIQNRVGKTRLAKWYMHFDDDEKQKLIEEVHALVTVRDAKHTNFVEFRNFKIIYRRYAGL YFCMCVDVSDNNLACLEAIHNFVEVLNKYFQNVCELDLVFNFYRVYTIVDEMFLAGEIRE TSHTKVLKQLFMLNSLEEVSIFTKILNREIPADIVYEDDQCFAFNDISPEAPTHILIVPR KPIPGVSSDCEILGKLLPAAKKIAEQDKGYRLVINNGPEGCQSVYHLHVHLLGGRQMTWP P---------------ERRILILGLDGAGKTTILYRLHVGEVITTIPTIGFNVETVQYKN LRFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSKDRDRIGISKQELMSML-EGRVKKAV LVVMANKQDIEGAMTVSEVAGALGLSALRNRKYQIFKTSALKGDGLEEAMEWLSTTLQQQ KXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXRLYVKAVFTGYKRGLRNQHENTALLKIDGVVEKNETEFYMGKRCCYVYRA KRLTATPGHKKANHLRVIWGKITRSHGNSGAVRAKFVRNLPPKAMGKRIRVMLYXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXMAARPLVSVHDSTGGATERNIRLPAVFKAPIRPDIVNFIHFQMQRNSRQPYAV SEKAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQAAFGNMCRGGHMFAPTKVWRRWHRR INVNQKRFAICSAIAATGIPALVMSKGHKIEETPEVPLVVSDDVQQLKKTKEAVKFLRKF KAWNDIVKVYNSKRYRAGIGKMRNRRRVMKRGPLVIYERDSGIVRSFRNIPGITLINVSA LNLLKMAPGGHIGRFCIWTEAAFKKLDALYGTTKADSKYKTGYRIPGQKMTNTDLSRLLR SDEIQRAIRDPVRN---------------------------------------------- -----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-KKKMKDAQMRAT INQKLIESGERERLKELLRTRLIESGWRDELKAYCKEIVKEKGLKHITVDELVAEITPKG KALVQDSIKRELLQKIRDFLAQ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSHRKFSKPRHGSLGFLPRKRSCRHRGRV KAYPVDDKSMPVHLTSFLTYKAGMTHVVREADRPGSKSHKKEIVEPVTILEAPPMVVVGI IGYIDTPKGLKSFKQVWAEHLSEDCLRRFYKNWYKSKRKAFTKASKKWSDKLGKELLEKD FSKLKKYCTVIRVIAHTQMRLLKKRQKKSHIMEIQVNGGTVAEKVDFARSMFEKKVDVGQ VFAQDEMIDCIGVTKGHGVKGVTARWHTKKLQRKTHRGLRKVACIGSWHPARVGFSVARA GQXGYHHRTEINKKIYRIGKGIHAKDGKVVKNNGATEYDPTEKTITPMGGFPHYGEVNXD FIMIKGCCMGPKK--VTLRKPLLVHTKRIAREKINLKFIDTTSKFGHGRFQTIAEKKAFM GRLKKDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXX----------------------EGDEMED-FSKKKKKKKTKV DAVDDLDDEPLEDESKKKKKKKLGSSRDYTYEELLERVYDILREKDPEMASGEKKKLIIR PPQVVRVGAKKTSFANYQDMCKTMKRDAKHFVNYLLSELGTSGSVDMNNQLIIRGRFQSK HVEQVLRRYIREYVMCHTCKSPETVLEKDTRLFFLRCETCGSRYSVQSITSGFKAVTGKR AALRAK--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-VPETLLKRRKINAEKSKTKRHEFFKRAE QYVKEYRTQARDKIRLTREARKHGSFYVPDEPKLAFVIRIRGINGIHPRPRKVLQLFRLR QINNGTFVRLNKATINMLRIAEPYITWGYPDLKSVRELIYKRGYGRIEGKRIGLSDNYLI EKILGKKDIICIEDLIHEIFTVGPNFKQANHFLWHFKLNTPNGGWTKKKNHFVDGGDYGN REDKINALLRRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMTKAHPPELKKFM DKKITLKINGGRMVKGTMRGYDPFMNLVLDDA-QELRGEKVIPIGVVVVRGNSLVSLETL ERL----PLRKFKLVFLGEQSVGKTSIITRFMYDSFDNTYQATIGIDFLSKTMYLEHRTI RLQLWDTAGQERFRSLIPSYIRDSYVAVVVYDIANEHSFQQTTKWIDDVKAERGNDVIIM LVGNKTDLSDKRQVSVEEGEQKAQELGVLFMETSAKAGYNVKHLFRRVAAALPDLSDSVS EGLVEVTLSD-PQPASDMAIKYDIAVGLAKGHSKTALKKKPSASKGRITKRAKEVRDIVR EITGFAPYERRMLELLKISKDKRALKFAKRRLGTHIRAKRKREEMTRTLHAMRKAXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---MNPEYDYLFKLLLIGDSGV GKSCLLLRFADDTYTESYISTIGVDFKIRTIQLDGRSIKLQIWDTAGQERFRTITSSYYR GAHGIIVVYDVTDQESFNNVKQWLQEIDRYAMETVTKLLVGNKCDLTAKKVVDYTTAKEY ADILKIPFLEASAKQSTNVEQAFMTMAAEIKGRMGPVSTNPVIDIKNSKPIRQSGSTCCX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------------------- --RELYGRLHVFDQHLNMVLGDVEETVTLVEIDEDTYEEIYKTSKRAVPMLFVRGDGVIL VSPAARTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHENQQEDASELLFPKEF DKADPLMISEVMSQNKRQQLDENAEIPKVFAQTLKYCQRRSKFKARESVSAVRSMLSQRR LHGFELAQLANLCPDTVEEAKVVLPSLQGRFTDEDLQSILDDLKTKISFQYXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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-------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKKGEKKKSTISEVVTREYTVNIHKRIHGI GFKRRAPRAIKELKKFAEKMMNTPDVRVDTRLNKHIWSKGVRNVPYRVRVRLARKRNEDD DSPHKFYTLVTYVACANFKGTQTINVDSKVCSEFIANQKYRLVRKIGSGSFGDIYLGLNV TNGEEVAVKMEAQKARHPQLLYESKLYKILQGGVGIPHIRWYGEKDYNVLVMDLLGPSLE DLFTFCSRRFTMKTVLMLADQMIGRIEYLHNKNFIHRDIKPDNFLMGIGRHCNKVFLIDF GLAKKYRDNKSRQHIPYREDKNLTGTARYASINAHLGIEQCRRDDMESLGYVLMYFNRTS LPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLR QLFRILFRTLNHQYDYTFD-----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMTRYSTDPENP TKSAKARGSHLRVHFKNTRETAQAVKRMHLRRAFRYLKAVIAKKEIVPFRRYNGGVGRKA QCKQFGTTQGRWPKKSAEFLLQLLKNAESNAEYKGLDTDHLAIEHIQVNRAPKMRRRTYR AHGRINPYMSSPRHVEVILAEREEAVAKSPKKKVSQKKLKRQKMQQRDXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXMGISRDKWHKRRKTGGRQNPIRKKRKFELGRPAAHTKLGP KRIHTLRTRGGNKKYRALRLDTGNFSWGSEAQTRKTRIIDVMYNASNNELVRTKTLVKNC VVQIDATPFRQWFEAHYATPLGRKKGSKLSEAEEAALNKRHKSTQRKYDERKKDAKVEQG LEDQFNAGRVIACISSSPGQCGRCDGYILEGKELEFYMRKIKAKKGRMSLVLPEKFQHIL RVMNTNIDGRRKIMFALTAIKGVGRRYANVVIKKADVDLNKRAGELTDDEVEKIITIMQN PRQYKIPDWFLNRQKDIKDGKYSQVLSNILDNKLREDLERLKKIRNHRGLRHYWGLRVRG QHTKTTGRRGRTVGVSKKKGSGTESDSDDDMPDLEEVAAAAGIQEDMVSKAKQSRSEKKA RKAMSKLGLKQVTGVSRVTIRKSKNILFVINRPDVYKSPASDTYIVFGEAKIEDLSQQAQ MAAAEKFKADEEVDETGVEAKDIELVMSQANVSRSRAVKALKNNQNDIVNAIMXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKWEY KEEHPFEKRRAEGEKIRKKYPDRVPVIVEKAPKARVGDLDKKKYLVPSDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGALYQDHHEEDFFLYIAYSDESVYGMRELRIQKL CLNICVGESGDRLTRAAKVLEQLTGQQPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAD EILERGLKVREYELRKNNFSNTGNFGFGIQEHIDLGIKYDPSIGIYGMDFYIVLSRPGFN IQQRRKQKSRIGFKHRITKDASMKWFQQKYDGVILPGKMGIKFLEFIKPFCAVLPEVSKP ERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVIMASNRGTLMELGIS PIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMIITVGQSIVYVMTGMYGDPSD IGPGVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVN TGRGTEFEGAIIALFHLLATRTDKVRGLREAFYRQNLPNLMNLMATIFVFGIVIYFQGFR VDLPIKSARYRGQYSSYPIKL--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------QTERAFQKQPTVFLNKKKTSTLRYYK SVGLGFKTPREAIIGHYIDKKCPFTGNVSIRGRILTGVVQKMKMQRTIVIRRDYLHYVKK YNRFEKRHKNMSVHLSPCFRDVAIGDVATVGECRPLSKTVRFNVLKIAKASGSKKGFSKF XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRVIRSQRKGPGS VFKAHTKNRKGAARLRAVDFAERHGYMKGVVKDIIHDPGRGAPLARVVFRDPYKYKLKTE TFIASEGMYTGQFIYCGRKANLQVGNVLPVGCMPEGTIVCNLEEKTGDRGKIARASGNYA TVISHNHDTKKSRVKLPSGSKKVIPCTNRAMVGVVAGGGRIDKPMLKAGRAYHKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGKASTVRRDTSAGRKVGLIAARRTGLLRGTK---- -AKRTRKVGITGKYGTRYGSSLRKMVKRMEISQHSKYTCQFCGKDKMKRNAVGIWRCHGC KKVVAGGAWVYSTTIAATIRSAIRRLREMREMGRRPARCYRYCKNKPYPKSRFCRGVPDP KIRIFDLGRKRARVDDFPLCIHMVSDEYEQIGSEAMEAGRICANKYLVKHSGKDAFHIRI RIHPFHIVRINKMLSCAGADRLQTGMRGAYGKPLGTVARVHIGQPIMSVRAKEQHKDDII EALRRAKFKFPGRQRLIISRKWGFTKWDRDVYPEMRKDGRLVPDGVSVQYRREHGPLALW MSDRRVTKILGRTGSQGQCTQVRVEFLDDSNRSIIRNVKGPVREGDILTLLESEREARRL RMTKGTSSFGKRHNKTHTLCRRCGRSSYHIQKKVCAQCGYPSPRKRKFNWSVKAKRRNTT GTGRMRHMKKVFRKFRNGFREGTVAKPRKVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGAYKYMQELYRKKQTDVMR YLLRVRSWEYRQLSTIHRASRPSRPDKARRLGYKAKQGFVVYRCRIRRGGRKKPVPKGAT YGKPTNQGVNSLKNQRSHQAIAEERVGRKCGALRVLSSYWVAQDSTYKYYEIILVDPMHK AVRVDPDMQWICKPVMKHREMRGLTSSNKKSRGLGKGHTFHKTIGGSRRANWKSKNSLSL RRKRGIAVGRLSEERKAWRKDHPFGFIARPIKNPNGTLNLMNWECAIPGKKGTPWEGGLY KIRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSLLDEEKDWRPAVTIKQILLGIQE LLNEPNIKDPAQAEAYTIYCQNKIEYEKRVREQAVKFKDPSLGKSSKMLQHINFRMRCTL QDGRTFIGTFKAFDKHMNLILGDCDEFRKVKPKAGKQREEKRVLGLVLLRGENLVSMTVE GPPPSDEGVARVPIPGAGPGPGMGRAAGRGVGMGGGLQGPVRGVGGPSPQHMAPGGMMGR GGPP-----LKLVLVGDGGVGKTTFVKRHLTGEFEKKYVATLGVEVHPILFHTNRGNIRF NVWDTAGQEKFGGLRDGYYIQGQCAIIMFDVTSRITYKNVPNWHRDLVRVCENIPIVLCG NKVDIKDRKVKAKTITFHRKKNLQYYDISAKSNYNFEKPFLWLARKLVGDCNLEFVAMPA LAPPEVNMDPTLAQKYEEELAAAQETALPDDDDDI------------------------- ------------------------------------------------------------ -------TPNIRVALKNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEI KEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQ KFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLD GFEPKQNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARADILKIHSRRMNLTRG INLRKIAEMMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFELAVAKVMQKDSEKNMSI KSYGKLGFAENFALSGAAAVISKTAAAPIERVKLLVQNQDEMIKQGRLTSPYKGVIDCTV RTFKTEGVLPFWRGNLANCIRYFPTQALNFAFKDKIKIMFKASKSDSGPLIFGKNIASGG VAGAMSLCFVYSLDYARTRLANDAKVAGKRQFNGLIDVYRKTLKSDGFVGLYRGFMISCA GIIVYRGCYFGFYDTLKPIVLGDDASLILPFMLGYCVTVSAGLVSYPIDTIRRRMMMTSG QAVKYKGSFDCATQILKNEGFMSLMKGAGANILRGVAGAGVLSGFDKFQS-------MTD CSDLDRQIEHLRRCEIIKESEVNSLCAKAREILVEEGNVQRVDSPVTVCGNIPGQFYDLK ELFKVGGDVPDTNYLFLGDFVNRGFYSVETFLLLLSLKVRYPDGITLIRGNHEGRKITQV YGFYDECLRKYGSLTVWRYCPEIFDYLSLSATTDGKXFCEHGGLSP-------------- ------------------------------------------------------------ ------------------------------------------------------------ VRLPPEVNRILYIRNLPYKITAEEMYDIFGKYGAIRQIRVGTTAETKGTAFVIYEDIFDA KNACDHLSGFNVCNRYLVVLYYQANKAHKKLDTEKKKEDLEAMKAKYGLATP---MSIGV PIKVLHEAEGHIVTCETTTGEVYRGKLIEAEDNMNCQMANITCTHRDGRVAQLENVFIRG SKIRFLILPDMLKNAPMFKRISAGRGKSAILRAAARGRGRGGPGRGRGGMQNEAGEYVDM YIPRKCSASNRIINAKDHASIQINLAEVDETTGRMTGQNRTYAICGAIRRMGESDDCLIR LAKKDGMIPKMARGPKRHLKRLNAPKHWMLDKLGGVFAPRPSTGPHKLRECLPIMIFLRN RLKYALTYDECKKIVKQRLIKIDGKVRTDMAYPAGFMDVITIEKTGENFRLIYDVKGRFI VHRITPEEAKYKLCKVKKVCVGPKGVPYVTTSDARTIRYPDPLVKVNDTIRVXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXMSSRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVR GKDIVVIGVEKKAVAKLQIDRTVRKIALLDDHVAMAFAGLTADARILINRARIECQSHKL TVEDPVTLEYITRYLAQLKQKYTQSTGRRPFGLSTLLVGFDGIPHLFQTDPSGTYHEWKA NAIGRSAKTVREFLEKEYNEKIASEKESIKLAVKALLEVVQSGGKNIELAYMKFNQPLKM MEPDEIEKYI-----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXAEFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYA NNSNYKNDTMIRKEAYVHKSVMNELRRIIEDSEVVQEDDELWPPPDRVGRQELEIVIGDE HISFTTSKIGSLIDVNQSKDPEGLRTFYYLVQDLKCIVFSLIGLHFKIKPIXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXMGDRYNIHSQLEHLQSKYIGTGHADTNKWEWL TNQHRDSYASYIGHFDMINYFSIAENEAKARVRFNFLEKMLQPCGPPPERPEDMKTELCA FSGFKIYPGHGKRIVKVDGRTFIFINAKSARSQLMKRNPRKICWTVLYRRKHKKGQQEEI SKKRTRRTTKFQRAITGATLSDIMAKRNQKPEVRKAQREQAIRAAKEKQRSKEKAAPKVG GKR--------------------------------------------------------- ------------------------------------RKSGRGCIVDSNLSVLNVVIFFKG EGEIPGLIHTTI------------------------------------------------ -----------------------------------------------------RVKARDL RGKKREELNKQLSDLKQELSALRVAKVTGGAASKLAKIRLVRKSIARVLTVTNQTQKENL RKFYKPIDLRLKKTRAMRRALTKHQLSLKTDK----------------EGAKTESVTHKV YFDITIGGENAGRIEIGLFGSAVPKTVDNFVKLATGE-GYKGSKFHRIITDFMIQGGDFT RGDGTGGKSIYFEDENFKLEHYGSGWLSMANAGKDTNGSQFFITTVETPWLNGRHVVFGK VLKGMKVVRKMEKTKTDSDKPANDVTIKDCGEIQVDSPF---------KKKKQALKFTLD CTHPVEDGIMDVSNFEKYLKDRIKINGKTGQLKNKLIITCSCLFSKRYLKYLTKKFLKKN NLRDWLRVVASDKDTYELRYFQINNDESEDEE--GKDEKGDDEKVYGGCEGPDAMYVKLV SSDGHEFIVKRDHALTSGTIKAMLSGPGQFAENETNEINFREIPSHVLQKVCMYFTYKVR YTNSSTEIPEFPIAPEIALELLMAANFLDCDKIIRLSDVESRKTSRESWIVIHNKVYDVT KFLEEHPGGEEVLLEVAGGNATENFEDVGHSTDARELMKDFEIGSLHPDDISTWSSYLIP LGIAIAAVLLYKFYMSYMLQHLRNGWQVDQAILGEEDRCVVIRFGHDWDPACMQMDEILY KCAEKIKNYAICFLVDISEVPDFNKMYELYDPCTVMFFYRNKHIMIDLGTGNNNKINWPL TDSQEFIDIIETIFRGARKGRGLVISPKDYSTKYRYXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--VPLNKEMI EQRVMLVLRLYDKVDPEKVTVDSHFMKDLGLDSLDQVEVIMAMEDEFGFEIPDVDAERLM KPSDIVQYICDKEDV---KKQFVDDLKNVEFETSEDVKVLPTFDSMGIREDLIRGIYAYG FEKPSAIQQRAIQPIVKGRDVIAQAQSGTGKTATFSISVLQSLDTQVRETQALVLSPTRE LAGQIQKVILALGDYMSVQCHCCIGGTNIGEDIRKLDYGQHVVSGTPGRVFDMIRRRNLR TRSIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLLSATLPHEILEMTSKFMTDPI RILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKM REANFTVSSMHGDMLQKEREAINEGVQIRASRVXITTDVWARGIDVQQ------------ ------------------------------------------------------XXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXLIVSLVVSVNCYFVTIDAHAEECYFDKVTSGTKMSLMFEVAEGGFLDI DVKITGPDGRVIYSGDRESNGKYTFSAHMDGVYKYCFSNKMSTMTPKIIMFSMDVGEKPK AHHNKLEEMINQLSTALTGVKHEQDYMEVRERIHRSINDNTNSRVVLWSFFEALVLVAMT LGQIYYLKRFFEVRRVVMSATLQPYLKAVRHTLTAAMALENFSSQVIERHNKPEVEVRSS KELLLTPVVISRNEKEKVLIEGSVNSLRISIAVKQADEIEKILCHKFMRFMMMRAENFVI LRRKALEGYDISFLVTNFHTEAMYKHKVVDFIIHFMEEIDKEISEMKLAINSRARISAEE FLKKFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXX---FDARFPNQNQSRNCYQNFMDFHRCQKVEDYE PCEYFKRVYTAICPEEWVEQWNNDIEVGAFPGKIXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPKELMHINIVVI GHVDSGKSTTTGHLIYKCGGIDKRAIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITI DIALWKFRTDKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVACGTGEFEAGISQNGQT REHALLAYTLGVKQMIVACNKMDMAEPPYSEARFKEVTKEVQTYLKKIGYNPKAIPFVPI SGFNGDNMMNMKWFDGWSVASGKSLFEALDSILPPARPTDKPLRLPLQDVYKIGGIGTVP VGRVETGILKPNTVVTFXPVGISTEVKSVEMHHES------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXMTRGRTELGEVTPHNIKQLKRLNQVVFPVSYNDKFYKDVL EVGDLAKLAYFNDIVVGAVCCRVDNSENQRRLYIMTLGCLAPYRRLGIGTVMLKHVLKVC EKDNNFDNVYLHVQVNNEVAIRFYEQFGFEIVEKKQNYYKRIEPADAFVLQKTFR-MPKQ IMEIKDFLLTARRKDAKSVKIKKNVKFKVRCSRYLYTLVIHDREKAEKLRQSLPPGLTVK ELKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------- ------------LCLKSREIFLSQPILLELEAPLKICGDIHGQDYDLLRLFEYGGFPPES NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT LFSAPNYCGEFDNAGSMMSVDETLMCSFQILKPADKKRFPYGGLNQGWPVTPPRNANKKG GK---------------------------------------------------------- ------------------------------------------------------------ -----------------------RRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDEL PPEFKLYLPVQNK-----ILNLEDPFADAAKIHIRIQQRNGRKTLTTVQGISPDYDLKKI VKACKKEFACNGTVVEHPEYGEVIQLQGDQRNSIKDFLLNNKLTDLVKVHGFXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXSGRVTTAVARHLPRVTKKKNALGCGFVGLRNIQTTPEVSSILEERILGQSKADLEET GRVLSIGDGIARVYGLKNIQAEEMVEFSSGLKGMALNLEADNVGVVVFGNDKLIKQGDIV KRTGAIVDVPVGEGLLGRVVDALGNAIDGKGAFKVSKRQRVGIKAPGIIPRTSVKEPMQT GIKAVDSLVPIGRGQRELIIGDRQTGKTAVAMDSIINQKRFNDGADESKKLYCIYVAIGQ KRSTVAQLVKRLVDEDAMKYTIVVSATASDAAPLQYLAPYSGCAMGEWFRD--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXMPKVRRSKKRPPEGWELIEPTLDELDAKMKEAETDP HEGKRRVEGMWPIFRIHHQKARYIYDLFYQRKAISRELYDYCLRENIADKNLIAKWKKQG YENLCCLRCIQTRDTNFGTNCICRVPKSKLEEGKIVECVHCGCRGCSGEYAQVAKMLGNG RLEAMCFDGVKRLCHIRGKLRKKVWINTSDIILVGLRDYQDNKADVILKYSPDEARNLKA YGELPEHVSINTENEDDVIFEDIDDILVQFLMKLSHETVTIELKNGTQVHGTVTGVDVSM NTHLKAVKMTVKNKDPVQLDSLSIRGNNIRYFILPDSLPLDTLLIDDAPKAKARSSNMNK PRSEMTPEEMSEREQEEFNTGPLSVLTQSVKNNTQVLINCRNNKKLLGRVKAFDRHCDMV LENVKEMWTEVPKAGKGKKKSKPVNKDGYISKMSLRGDSVILVLRNPLXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXA GDAVKGKKLFVQRCAQCHTTEKGGKHKTGPNLNGLIGRQTGQQQGFTYTDANKKKGITWG KDTLWIYLENPKKYIPGTKMVFVGLKKKQERADLIAHLLEATKIYVERTLCIIKPDAVTE EIEDIILRSGFSVLQKRRVRLTPEQASDFYAEHYGKL-FPSLVAYMSSGPVVVMVLAKDK SISHWRELIGPTNTVKARQTHPDSLRAIYGTDDQRNALHGSDCFSSAEREIRFFFSDAII EPVAVGQASKDYLSKAVNPTLLKGLTELCKQKPQEPVEWLADWLLQNNPNKPRI-MFEAC LAQGSLLKKVLEAVKDLLSEGIFDCNGTGMSMQGMDSSHVSLVSVLLRGEGFDDYRCDRN LSLGFNLGNLSKIMKCAGNDDSITLRAEENADTVTLTFKSPKQEKVSDYEMKLMDIDQEH LGIPDQEYSCTVKMPSAEFQRICRDLSQIGESMVIACTKEGVSFSTSGDLGSGNIKLAQT SSVDKEEESVTIEMEEAVNLTFALRYLNFFTKATPLSAXVELRMSADVPLVVEYKIADMG HICYYSSKDRDD----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXMLMPKKTRIAIFEHLFKEGVMVAKKDYNAPKHPELEVRNLHVI KALQSLKSKGYVNEQFAWRHYYWYLTNEGIQYLRDFLHLPPEIVPSTLKRQ-PQSDREAY RRAGGGDKKADVGAGAQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX MTNTKGYRRGTRYMFSRKFRKRGVIPISTYLKVYKRGDIVDIKGNGAVQKGMPHKSYHGK TGRIYNVTPHAVGVIVNKRVRGEILPKRINVRVEHIKHSNCRLDFLKRVKRNSELKKESK AKFICKRIPEQPKPAHFVRTKYNKPVVLAPLPYEFIAXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMATQVKVAKTDTKNNGEHDKEQQ EAIEMIDDVQNEIDRLNESASEEILKVEQKYNKLRQPHFQKRSDLIAKIPNFWVTAFVNH PQVSALLSEEDEEALQFLSKVEVQEFEDIKSGYKINFTFDSNPYFENDMISKEFHLNSSK STPIKWKPGKDLTKKSQKRSHEEQESFFGWFNDHGDAGADELGEVIKDDIWPNPLQYYLA SEIEEDVGLGEGEEDEEKKLTKEEELLLQDFSRNVSTKSSALFYGNAFIVSAIPLWLFWR IHQMDPYIFFAVMTIISTYLVAMAYKNVKFVLKHKIAIKREEAVTREVMKNVGDDKKMTR KEKDERILWKKNEVADYEATTFSIFYNNALYLVLVLVVSFYVLRTMTPALNYVLSVGSAS ALLALFSTST---QGKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQT VCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVKELQRQ ASPNIVIALAGNKADLRMVEFEDAQAYAEENSLLFMETSAKTAMNVNDIFLAIAKKLPKS EQGV--PRENXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-ENEELLDYD--DENEAKEVKGTYVSIHSS GFRDFLLKPELLRAIVDCGFEHPSAVQHECIPQAILSMDVLCQAKSGMGKTAVFVLATLQ QIEPVDGQVSVLVLCHTRELAYQISKEYERFSKYMNGIKCAVFFGGMLIKKDEEVLKKNC PHIVVGTPGRILALIKALNLKNIKHFILDECDKMLEQLDMRRDVQDIFRQTPHEKQVMMF SATLSKDIRPVCKKFMQDPIEVYVDDDSKLTLHGLQQHYCKLKDNEKNRKLFGLLDVXEF NQVIIFVKSVQRCMAL-------------------------------------------- ----------------------------------------------------PPCYADLG KKSRDLFGKGYNYGLFKLETKSKTDNGVQFTVSGNSNSDTGKVFGGLETKYKLADYGTTF TEKWTTDNVLNTEITIEDQLVKGLKLAFDTSFAPNTGKKSGKIKTAYKADYVHLNCDVDF DFAGPTINGAAVLGYQGWMAGYQMKFDKSKLSRNNFCVGYEQGDFTLNTSVNDGSEFIGD VYQKVNKKLETGVNLTWVAGSNSTRFGLAAKYNYDDDTVMRAKVNNAGQVGIGGTLKLRD GVSLAGSFLIDAKNFNAGGHKVGLGLDFEAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMVDS LGTILLKFYNHYVNDTSKKLKIIDAYLLYILLTGIFQFLYCCLVGTFPFNSFLSGFISCV GSFVLAVCLRVQVNPQNKNDFHGISPERAFADFIFAHVILHLVVMNFIGTLSSPTQLLPL ELVDKCIGSRIHIIMKSDREVVGTLLGFDDFVNMVLEDVTEFESTPEGRRVTKLDQILLN GNNITMLVPGGEGPEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXMLVLVLGDLHIPHRCNNLPQKFKKLLVPGKIQHILCTGNLCTKES FDYLKTLASDVHVVRGDFDENLNFPEQKVVTVGQFRIGLCHGHQVVPWGDTESLAMIQRQ LDVDILISGHTHKFEAFEHENKFYINPGSATGSYNALDSNVLPSFCLLDIQQSTVVAYVY QLVGDEVKVERIEYKKMGKFMKSGKVVLVLGGKYAGRKAVIVKNYDDGSSERPYGHCLVA GIDRYPRKVTKRMGKKKIAQKSKLKAFVRTYNYNHLMPTRYSVVPLDKTVINKDAFRDPA LRRKARREAKMKLEERYKTGKNKWFFTKLRFXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-- ----------AREKASKASKVVVKGTHQKRQKKIRTTVHFRRPKTLRLARTPKYPRKSTP ARNKLDQFKIVKFPLTTESAMKKIEDNNTLVFIVDKKSNKPQIKMAVKKLYDIDVGKVSC LIS--------------------------L---KQRMRLANEKHSKNVLQRGNVPKTLKS EEEKYPVGPWLLALFIFVVCGSAIFQIIQSIRMXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX X---------------ERRILILGLNGAGKTTILYRLQVGEVVTTIPTIGFNVQTVTYKN LKFQGWDLGGQTTIRPYWRCYYSNTDAIIYVLDSMDRDRIGISKQELISMLEEDDLRESI LVVLANKQDIEGAMSVTEVANALGLMELKNKKYHIYKTSAIK-KRLDDAIEWLVNTLQCK KSLYFHIGETEKKCFIEEIPDDTMVVGIYKVEAHEPTSGRYVPTGPEFGMFVQVTDTEHK TILARTYAAEGRFTFTSHTAGEHTVCLHSNSSAWFGGGQLRVHLDIQVGEHANDYQQIAT KDKLTELQLRVRQLLDQVDQIQKEQNYQRTREERFRQTSESTNQRVLWWSIIQTLVLLVT GAWQMKHLKSFFEAKKLVMFFHVSLEHDILLHPRYLGPNLLNTVKQKLFTEVEGTCSGKY GFVIAVTTIDNIGAGMIQPRRGFVEYPVKYKAIVYRPFKGEVIDAVVTQVNKVGLFVEAG PLSCFISRHSIPMDMEFDSNSNPPCYKTKDEDVVIQQDDEIRVKIIGTRVDATDIFAIAS LMDDFLGLVSRLYCKAVFTGYKRGLRNQHETTALLKIDGVLRKTQTDFYLGKRCAYVYKA RNKTACPGHKNASRIRVIWGKITRPHGNSGAVRAKFRKNLPSTAMGKRIRVMLYXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPQNEHIELHRKR HGYRLDYHEKKRKKEGRKPHEMAHKAKRLRGIRAKLYNKKRHAEKVQMKKTIKMHEERRT KQKKDDIVPEGAVPAYLLDREGQSRAKVLSNMIKQKRKEKAGKWEVPLPKVRGMSEAEVF RVVRTGKTKRKAWKRMVTKVTYVGEGFTRKPPKYERFIRPMALRFKKAHVTHPELKATFH LPIIGVKKNPTSSLFTSLGVITKGSVIEVNISELGLVTQGGKVIWGXYAQVTNNPENDGC INAVLLVMAARPLITVYNEKKEQTGTNITLPAVFRAPIRPDIVNFVHFEMKKNSRQPYAV SKAAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRR INVNQKRYAICSAIAATGIPSLVMAKGHRIEEIPEVPLVISDKIEEYKKTKEAVAFLKKF KAWNDIKRVYATKRFRAGKGKMRNRRRIQKKGPLIIYNQDNGICRAFRNIPGITLINVSR LNLLKIAPGGHVGRFCIWTESAFKKLDGLYGTWRKESKEKKNYNLPMHKMTNSDLSRLLK SEEIQRVLRAPKRSNKRRILKK-------------------------------------- -----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXMSHTILLVQPKPAPETRTYSDYESLNECLEGVCKIYEEHLKRKNPNSPSITYDISQ LFDFIDSFPDLSCLVFYKESATYCPHNKEWIKEKIYTLLRKQAG-------EKKVESVK- --HTYPLIRHSDMQEEIRVEAMELCVTACEKFANNNEGAAKMVKETMDKKFGASWHAVVG EGFGFEITHETKNLLYMFFGGNLAIILWKCSMSHRKFSAPRHGSLGFLPKKRSIRHRGKV KAFPKDDPTKPCHLTAFLGYKAGMTHVVRDLDRPGSKMNKKEILEAVTIVETPPMVVVGV VGYIETPKGLRTFKTLFAEHLSEECRRRFYKNWYKSKKKAFTKSSKRWQDEDGKKSIEKD FAKMKKYCKVIRVITHTQIKVMKKRQKKAHIMEIQINGGNISQKVDWAREKLEKCVPVGN VFAKDEMIDVIGVTKGRGFKGVTSRWHTKKLPRKTHKGLRKVACIGAWHPARVGFSVARA GQKGYHHRTEMNKKIYRIG----------------------------------------- ------------------------------------------------------------ ------MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLG LWDTAGQEDYDRLRPLSYPQTDVFLVCFSLISPASFENVRAKWYPEVSHHCPNTPIILIG TKLDLREDKETAEKLKEKKLAPINNIQGMAMAKEIGAVKYLECSALTQKGLKTVFDEAIR AVLCPVPKKKKTKKCRMLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXX---------------------------------------------------- ------------------------------------------------------------ -------------------------------------------------PIKALKEHSKE AYCIDWSQRGESAIVSGSWDHTIKLWDLIQP-------HSLSTYQGHEGVVYSTVWSPHV PGCFASTSGDRTLRIWSTQKPYMAQI--VIPAHDSEILTCDWCKYDQNIIVTGAVDCSLR GWDIRNPKAYLFELRGHQYAVRRLKCSPFHKTVIMSCSYDFTVRLWD------------- ------------------------------------------------------------ ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQVLESLLKKRKQNEEKQKVKRREIFKRAE KYIKEYRIKERDEIRLAREAKKHNNFFVPAEPKLAFVMRIRGINGVHPKPRKVMQLFRLR QINNGVFVKLNKATINMLRIAEPYITWGYPNLKSVRELIYKRGYGKVDGRRIPLTDNAII EKKLGQYGIICMEDLIHEIFTVGPHFKQASNFLWYFKLNTPNGGWRKKNNHYIDGGDFGC REDKINALLKRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSKAHPPELKKYM DKRLSLKLNGGRQVTGILRGFDPFMNLVIDESVEVMKTGEQNTIGMVVVRGNSIVLLEAL DRIEFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTI RLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFQQTSKWIDDVRTERGGDVIIM LVGNKTDLSDKRQVSTEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGME---- -----------------MVLRYDMAVGLDKGHKVTVTRPRPSRRKGKLTKHTKFIRDLVR EVVGFAPYERRCMELLKVSRDKRALKFVKKRLGGHIRAKKKREEMQQTVMKIRKAXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------FLDDVRRMNKRQLYYQ VLNFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFYRGDLLFLAHDREESIRVGE IVVFKIEGRDIPIVHRVLKVHEKEDGKVKFLTKGDNNSVDDRGLYAPGQLWLEKKDVVGR AKGFIPYVGIVTILMNDYPKLKYAILACLGIFVLLHREXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------- ------------------EEHSCEFGSMKYYALCGFGGILSCGLTHTALVPLDLVKCRIQ VNPAKYGSIFHGFSVTVKEGGLSALTLGWAPTLIGYSMQGLCKFGFYEVFKIFYSDLMGE ENTFLYRTSLYLAASASAEFFADIALCPMESVKVRIQTTEGWSTTLREGAPRIWKEEGIN GFYKGLVPLWARQIPYTMMKFACFERTVEALYKFVVPKPRSECSKGEQLLVTFTAGYIAG VFCAIVSHPADTIVSKLNQAKEA-LCRSAKGLGFMGMWKRFGSRIIM------------- -------------------------HWKLERITAASLIGVIPATLYFVSDYLFTTVVLHA HWGMAGIFGDYIHMSITAFAGLCYYNYTDIGIINLIKYLWTK-NEQQEENASQLKFPKEF ENAETLLVSEVQRKQQNENAEEERELSEVFMKTLNYTQRFSRFKNRETITAVRSLLMQKN LHKFELAELANLCPENAEEAKALIPSLEDKFEDDELQQILDDIQTKRSFQYXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXMADLLLDSAIRLWVFVPIVVITFLVGILRHYV TIALSSDKKVEKQQVTDSQMLIRSRILRDNGRFIPKQSFHMRKHFLNNEENGYFAKNPMT DPSMMTDMLKGNLTNVLPMIVIGGWINWAFSGFLTTKVPFPLTFRFKPMLQRGVELISLD ASWVSSASWYFLNVFGLRSMYNLILGQDNAADQTRAMQDQMSGAGMAMPQDASKAFKAEW ESLEISEHYWALERVEDELIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIIRRNPPGTKAENWFHWPDMTFEEMDSTL AVQQYIQQLIRRDCSLIDEILTPP-GQDEGVWKYEHLRQFCMELNGLAVKLQTSCNPESC TQMTATEQWIFLCAAHKTPKECPAIDYTRHTLDGAACLLNSNKYFPSRVSIKESSVAKLG SVCRRVYRIFSHAFFHHRVLFDEYENETALCKRFTTFVTKYSLMSKDNLIVPILEEQ-PN IKLQSSDGEIFEVDVEIAKQSITIKTMLEDDEDDEEPVPLPNVNAAILKKVIQWCTYHKD DPPAPDDDENKEKRTDDISSWDSEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMI KGKTPEEIRKTFNIKNDFTPAEEEQVRKENEWCEEKNKRLTKGGKKGKGKKVVDPFTKKD WYDVKAPAMFNIRQIGKTLVTRTQGTKIASDGLKGRVFEVALADLQNDEISFRKFKLMAE DVQGRNVLTNFHGMNLTTDKLRSMVKKWQTLIEANIDVKTTDGYLLRVFCIGFTKKRQNQ IKKTCYAQSTQIRMIRRKMVEIMMREISSNDLKEVVNKLIPDSIAKDIEKACQGIYPLHD VHIRKVKVLKKPKFDVGKLMDLHGEGSTTVTGEGGEVIVRPDNYEPPVQQDVXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXM AKHHPDLIFCRKQPGVAIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGSYQGRCVIC GGPGVSDAYYCKECTITEKDRDGCPKIVNLGSAKTDLFYERKKYGFKKRXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXRIKVANPVVELDGDEMTRIIWEKIKEKLIFPYVDVECLYYDLGLPYRDQTDDQVTIDA AHAIKKHSVGIKCATITPDEERVVEFSLKKMWLSPNGTIRNILGGTVFREPILCSNIPRL VPGWKQAITIGRHAHGDQYKATDFVANGAGKLELVFTPKNGQPHRMPVFDFKESGGVGMA MYNTDESIKGFAHACFQYAIQKKEPLYMSTKNTILKRYDGRFKDIFQEIFEKXYTKQFDD AKIWYEHRLIDDMVAQCLKSLVD-LFGLVDYDGDVQSDIV-------------------- ------------------------------------------------------------ ---------------------------------------------XXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------- ------------------------------------------------------------ ----------DLFGSAAEKLKQQRLAEYAAKKAPGAIAKSTIILDVKPWDDETDIGEIEK CVRSVAKEGLLWGASKLVPVGYGXKKLQIACVVEDDKVGTDFLEESITAFEDLVQSVDIV AFNKVKVQEIREVTRIERIGAHSHIRGLGLDDALEARNVSQGMVGQLAARRAAGVILEMI KEGKIAGRACLIAGHPGTGKTAIAMGMAQALGTDTPFTAIAGSEIFSLEMSKTEALTQSF RKSIGVRIKEETEIIEGEVVEIQIDRPATGTGAKVGKLTLKTTETETIYDLGQKMIESLT KEKVQAGDIITIDKATGKITKLGRSFTRARDYDAMGPQTKFVQCPEGELQKRKEVVHTVS LHEIDVINSRTQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKADIVPGVLFIDEVHM LXLECFSFLNRALESDMAP----------------------------------------- ------------------------------------------------------------ ----------------------------------FDLTSRMGQYLDRHLVFPLLEFLSVK ELYDEHEMLKGKLDLLSNTNMVDFAMDVHRGLYPDQDVPTGLVEKRQNVVAQLKSLQSAT EPIVKIFEDGEVQIQNSRDGRQLMEFLEKDYNFSPMMLDTLYNFAKFQYECGNYSGAAEY LYFVRVLVPPNDKNALNALWGKLASEILMQNWETALDDLNRLKDVLDSPLQALQQRTWLI HWSLFVFFNHPKGRDLIIDMFLYQQQYLNAIQTMCPHILRYLTTAVITNKAVLKDLVKVI QQESYTYKDPITEFLECLYVNFDFDSAQQKLRECETVLVNDFFLVACLDDFKENARLXIF ETFCRIHQCISI------------------------------------------------ -----------------------------MGVEKETTKEGDGQTYPKKGQQVHVHYTGTL TNGKKFDSSRDRGKPFSFKVGAGQVIKGWDEGVAQMSLGERAKLTCSPDYAYGPKGYPGV IPPNATLIFDVELL-----KYFCDYCDTYLTHDPPSVRKTHCSGRKHKENVRLYYPKWLE EQVQKLVDDTTAAFKQGKINNNPFGNGGAMIPPPGKG-GPPHGPPMGPMGPPPMG--PPM RPPMGPMGPMMRMMGPPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXFSALVVLAVAKETVHFSEEFWEDRWIKSTHR-SDG GEWKLTAGKFYGDAEKDKGIQTSQDARFYGISAKFEK-FSNKDKTLVIQFTVKHEQNIDC GGGYIKLFGDDLKQTDMHGETPYNIMFGPDICGPGTKKVHVIFTYKGKNLLTKKDIRCKD DVFTHLYTLIVKPDNTYEVKIDNEKVESGDLEADWDFLPAKKIKDPEAKKPEDWDENEKI PDPEDKKPEDWEKPEHIPDPDAKKPEDWDDEMDGEWEPPQIDNPEYKGEWKPKQIDNPNY XGVWVHPETDTQN-TNQMIPIQYDDIAGIGLDVWQXKAGTIFDNFLL------------- --------------------------------------------XXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-NVFRLTGDLSHLGAIIILLIKI WKSRSCAGISGKSQILFAIVFVTRYLDLLTNFISVYNTSMKVLFIAGSLTTVILMYFKFK ATNDSNHDTFRMEFLLVPIGGLSFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGE AETITSHYLFALGSYRALYILNWMYRYYFENYFDLIAVVAGCVQTILYCDFFYLYITKVL KGKKLSLPAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMTVFSLTLIRHGETQENKIKIIQGHLDTILSDHGCLQAKLLGHRLQFEEYSH--IYT SDLKRANQTGQFVLDGNKVSCCDVVKDIRLRERCFGSWEG-------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXMGIDICHKNDRKVRRTEPKSQDIYLRLIVKLYRFLARRTNA KFNKIVLRRLFMSKNNRPPLSLARLVRNMKKPGREGKMAVVIGTITDDLRILEIPKLKVC ALRLTAGARARILKAGGEIITFDQLALRAPKGQNTVIMQGPRKSREAYRHFGPAPGVPHS HTKPYVRSKGRKFETARGRRKSRGY--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKSPEPVEGRKHIDVQT ELYLEELSDRVEEADVDTQTDAFLDRPPTPLFVPAKTGVDICTQILEGDLFDFDIEVKPI LEVLVGKSVEQSLLEVMEEEELANLRSQQRAFEELRNAELVEQQRLEEQERXHREEKERR MKQQRDILR-NKRSCRKIAARAFSQSYLADLVPSVFGTLAD------------------- ------------------------------------MKARGDLKEYKVIGRRQPTDKMRT PALYQLRIFAPDSVVARSRFWYFVSQLKKMKKTTGEIVCCQRIYEHKPHSIKNFGIWLRY DSRSGTHNMYREYRDLTTSGAVTQCYRDMGARHRARAHAIQIMKVAYVKAKDCRRPNIKQ FHDSKLKFPLPRPVTRQLHKPRFTTRRPTTVFXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXKPNYTLKFTLAGHTKAVSSVKFSPNGEWLASSAADKLIKIWGAYDGKFEKTISGH KLGISDVAWSTDSRLIVSASDDKTLKIWEQASGKCLKTLKGHSNYVFCCNFNPQSNLIVS GSFDESVRTGKCLKALPAHSDPVTAVDFNRDGSLIVSSSYDGLCRIWDTASXQCLKTLIY DDNPPVSFV--------------------------------------------------- ------------------------------------------------------------ ---MIIFKDIISGDELFSDIYPDFVYEVEGKKGVNTGANASTGIDVVLANKKSYTTYIKG YMKGIKEYEFYTGVILVEHETPYLILFKDGVVDEKVMAVEFDGGVVIGADSRTTTGSYVA NRVTDKLTKVTDYIYCCRSGSAADTQAIADIVNYHCSFHKMEIGEEPKVKTAAHIFQELC YSYRDQLTAGIIVAGWDKKNGGQVYSIPLGGMCVRQAVSIGGSGSTYVYGYVDSSFKEGM TKEECLDFTAKTLALAMFRDGSS---------------------------XXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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------------------------------------------------------------ ---------------------------------------------XXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXCKVLITELTNRLKET-DSSEVFTLGHGLDKKKKLHYKNSDLRLIEALQDPHVC DKILEYNIHKERKGSNRFAKGMSETFQTLHGLMDKGVKVDLGIPHDLWDKPSAEVTMMHK KCYQMAEDYEEDIEDWHYNHQEDLATFICAQRVLKNTSDXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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------------------------------------------------------------ EQHSFGIEPISCHAFNGDRKQIALPNDDEVVIYKKDWEKQDVLQEHAQRVTGIDWAANSN RIVTCGVDRNAYVWPTLVILRINRAATCVKWSPLENKFAVGSGARLLSICYFEQENDWWV SKHIKKPIRSTVTSLDWHPNNCLIGSGSSDFKARVFSGYIKEVDSKPEATPWGKKMTFGN LMAEFSNGGGWVHDVSFSGSGNKLAWVGHDSSISVVDAFVKTEFLPFTSLSFVTENSLVV AGHDCCPMLFTHDDAGI------------------------------------------- -----------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXAIQCYQCDSNEDDSCPSSETFDTTVNALVDCAGMDAKVPGTFCMKIIQRSSG WNAWEKITRRCGSRSDLGVAWGCRFSYVDMGVFQEICYCLDKDGCNGSQKIDSEDAENPQ LVSEYVNDIYDYMRQLETDEINARMRGILVDWLVQVHSRFHLLQETLFLSVAIIDRFLQE EVARSKLQLVGVTAMCIASKYEEMYAPEIADFVYITDNAYTKNEIR-------------- ------------------------------------------------------------ ------------------------------------------------------------ -XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXX-KLTDQVVRTFQVAKVFRENTDKINSLDFSANGETLISSSDDDQIVIYD CQNGTPKRTLNSKKYGVDLIRYTHGANQAIHSSTKVDDTVRYLSLHDNKYIRYFPGHTKK VVTISMSPIDDTFLTGSLDKTIRLWDLRSQNCQGLMHLPGRPVAGFDPEGLIFAAGINSE MVKLYDLRSFDKGPFATFKLPQDKDCDWTGLKFSPDGKLILISTNGQVVRLIDAFEGKPL QTFMGHTNMKGIALEASFSPDSQFVFSGSTDGKIHCWNAETGSKVSVLEGGHSGPVQCVQ FNPKFMMMSSACTNMAFWL-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX >Themiste_lageniformes -TDRKAVIKNADMAEDMQQDAVDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSG--TQLRQFQTSAVQRDIDQAAKYIGAGAATV GAAGSGAGIGSVFGSLVIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLILFAFM SHYKETGKAPGTPIHRIRITLTSRNVKSLEKVCSDLIQGAKEKNLKVKGPVRMPTKILRI TTRKTPCGEGSKTWDRYQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADMDQVM QFVDPAKTFAKDSIRLVKRCTKPDRKEFQKVAIATAIGFAIMGFIGFFVKLIHIPINNII V-ATPVSKKKKFVADGLFKAELNEFFTRELAEDGYSGVEVRVTPTRTEIIILATRTQQVL GDKGRRIRELTSVVQKRFNFPEGTVELYVEKVANRGLCAITQCESLRYKLIGGLAVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGEPCNDYVDMAIRHVLLRQ GVLGIKVKIMLPWDPSGKMGPKRPLPDHVSIVEPKEEILPTQPISEQKGGKMSKRGRGGT AGGKFRISLALPVGAVINCADNTGGKNLYVIAVNGIKGRLNRLPSAALGDMIVATVKKGK PDLRKKVLPAVIIRQRKFIKRKDGVVLYFEDSAGVIVNNKGEMKGSAITGPVAKECADLW PRIASNASSIRKGKKEVVSLGPQVVEGENVFGVAHIFASFNDTFVHITDLSGKETIVRVT GGMKVKADRDEASPYAAMLAAQDVAERCKQLGITALHIKLRATGGNKTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRLXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--- ATIRTRKFMTNRLLSRKQMIVDVLHPGRATVPKTEVREKVARMYKTTPDVVFAFGFRTNF GGGKTTGFALIYDSLDFAKKFEPKHRLIRHGARKKRKERKNRQKKVRGIAKAKVG-MPKI PLVCSKTYTTPRRPFEKERLDQELKLIGEYGLRNKREVWRVRYTLAKIRKAARELLTLDE KDPRRLFEGNALLRRLVRIGVLSEDKMKLDYVSGLRLEDFLERRLQTQVFKLGLAKSIHH ARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFALKSPYGGGRPGRVKRKNMKKGKGGG DAMGNVFASLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFAVDSNDRERVGEAREELMRMLAEDELRD AVLLVFANKQDLPNAMNAAEITDKLGLHSLRQRNWYIQATCATSGDGLYEGLDWLSNQLK SLKMPLARDLLHPSLEEEKSKCKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRRKQHMVRMNVLADALRSIGNAEKRGKRQVLIRPSSKV IIRFLTVMMKHGYIGEFEVIDDHRAGKIVVNLTGRVNKCGVISPGFDIALRDMEKWTTNL LPSRQFGYLVLTTSGGIMDHEEARRKHLGGKI------GRMHAPGKGISQSSLPYRRTVP TWLKLNSEDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVAGNKILRILKAKGLAPD IPEDLYQLIKKAVAMRKHLERNRKDKDSKFRLILVESRIHRLARYYKTKRVLAPNWKYES STASAMVAVAELPEVKLFAKWSADDVQVSDISLTDYIAIKEKYAKYLPHSAGRYQVKRFR KAQCPIVERLTSSLMMHGRNNGKKLMAMRIVKHAFEIIHLLTGENPLQVLVNAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQALWLLCTGAREAAFRNVKTIAECLADELINAAK GSSNSYAIKKKDELERVAKSNRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXMSEEKKDETEHINLKVTGQDGSVVHFKIKKNTPLRKLMS AYCDRTGFKMDSMRFRFDGQPINETDTPSVLEMEDGDSIDVFQQQTGGXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXMSEAEGDDVPVTAGAGGAMDLNTAIQEVLKTALVHDGLARGLHEC AKALDKRQAHLCILANNCDEPMYVKLVEALCAEHGINLLKVDDNKKLGEWAGLCKIDRGG QARKVVGCSCVVVKDYGKETQAHDVLNEYFKSKKXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMDDFQSGEETAFVVDEVS NIIKEAIEGAIGGNTYMHNKVNQWTSNVVEQCLNQLTKLGKPFKYIVTCVIMQKNGAGLH TASSCFWDNTTDGSCTVRWENKTMYCIVSVFGLAIMFSANAKILKPPGEKPDEFESSISQ ALLDLEMNSDLKAQLRELNISAAKEIDVAGKKAIIIFVPVPQLRSYQKIHVRLVRELEKK FSGKHVVFVAQRRILPKPTRKSRVKSKQKRPRSRTLTAVHDAILEDLCYPAEIVGKRIRI KLDGSRLVKVHLDKSSQTTIEHKVDTFTAVYKKLTGKDVNFEFPEYVLXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSGGLDV LALKEDDVTKFLASGTHLGSNNADYQMEQYVYKRKTDGVHIIDLRKTWEKLLLAARAIAA IENPADVCVISARPYGQRAVLKFAAATGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDP RTDHQPVTEASYVNIPVIALCNTDSPLRYVDIAIPCNNKGEHSIGLMWWLLAREVLRLRG TISREVPWDVMVDLYFYRDPEEAEKE---------------------------------- -------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTEKGKKKSAINEVVTREYTINIHKRIHGI GFKRRAPRAIKAIREFAHKMMGTPDVRIDTRLNKHMWSKGVRNVPYRVRVRLARKRNEDE DSANKLYTLVTYVPVTTFKGTQTVNVDTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMTRYSLDPENA TKSVKARGSHLRVHFKNTRETAQAIKHMHLRRAERFLKAVTRKQECVPFRRYRKGCGRQS QAKNHNASLARWPQKSANFLLQLLKNAESNAEYKGLDTDHLVIEHIQVNRAPKMRRRTYR AHGRINPYMSSPCHIEVILAEREQAIAKAAKKKVSQKKLKRQKMMMRDKKGGPKPELTEE QKLEIREAFDLFDADGSGYIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGQIDFND FLRIMTEKMSEKDSKEEILKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQEADRD GDGEINEQEFLRIMKKTSLYMGISRDKWHKRRKTGGRKNPIRKKRKFELGRPSANTKIGA RRIHTVRTRGGNKKFRALRLDAGNFSWGSEATTRKTRIVDVVYNASNNELVRTKTLVKNC IIQIDATPFRQWYEAHYALPLGRKKTSKLTEAEEEVLNKRSKKTMKKYITRRKTAKVEQA LEEQFSTGRILACLSSKPG----------------------------MTLVLPDKFQHIL RVMNTNIDGKRKVPFALTAIKGIGRRYALIVCKKADIDPSKRAGELSEEEVEKLMTVVQN PRQYKIPNWFLNRQKDIKDGKYSQVMSNALDNKLREDLERLKKIRAHRGLRHYWGLRVRG QHTKTTGRRGRTVGVSKKKDDGTESDSDDDVPELEDVAQAAGLNEDLPSKLKQSRSEKKS RRSISKLGLKNVQGVSRVTIRKSKNILFVINRPDVYKSPASDTYIVFGEAKIEDLSQQAQ MNAVEKFKTDEPVDDTGVEQKDIELVMSQANVSKNKAIKALKDNNNDIVNAIMMGRVRTK TVKKASRVIIEKYYTRLTLDFHTNKRICEEIAIIPSKKLRNKIAGFVTHLMKRIQRGPVR GISIKLQEEERERRDNYVPEVSAIEEVDPDTKEMLKAMDMANIPNLQVT------MKWEY KEEHPFEKRRAEGEKIRKKYPDRVPVIVEKAPKARVGDLDKKKYLVPSDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGALYQEHHEEDFFLYIAYSDESVYGMRDLRVRKL CLNICVGESGDRLTRAAKVLEQLTGQQPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAE EILESGLKVREYELKKGNFSDTGNFGFGIQEHIDLGIKYDPGIGIYGMDFYIVLGRPGYN VAYRRRRKSVVGCKHRVTKEESMKWFQQKYDGIILPGKXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQTEKAFQKQPTGFLNKKKALLQRYYK NIGLGFKTPREAIDGHYIDKKCPFTGSVNIRGRILTGVVLKTKMIRTIVIRRDYLHYIKK YNRFEKRHKNMSVHCSPCFRDVAIGDIVTVGECRPLSKTVSFNVLKVTKASGQKKAFSKF MVNVPKARRTFCKGLKCRKHTLHKVTQYKKGKDSLFAQGKRRYDRKQSGYGGQTKPVFHK KAKTTKKITLKMECTECKTRKQLPIKRCKHFELGGDKKKKGQMIQFMGRVIRSQRKGAGS VFKAHTKNRKGAAKLRALDYAERRGYIKGVIRDIIHDPGRGAPLAKVAFRDPYRYKTRTE TFIAAEGMYTGQFVYCGKKATLQVGNILPVGVMPEGTIICCMEEKTGDRGKIARTSGNYA TVIAHNVDTKRTRVKLPSGTKKSVPSSNRAIVGIVAGGGRIDKPLLKAGRAYFKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGMASTVRRDTSAGRKVGLIAARRTGRLRGSKQLTG KAKRTKKVGIVGKYGTRYGASLRKTIKKMEVSQHGKYTCNFCGKEAMRRKAVGIWACKRC RKVVAGGAYVYATMAAATVRSAVRRLREIKE-GRRPARCYRYCKNKPYPKSRFCRGVPDP KIRIFDLGRKKARVDDFPQCVHLVSDEYEQLSSEALEAGRICANKYLVKMCGKDAFHLRV RPHPFHINRINKMLSCAGADRLQTGMRGAYGKPQGTVARVHIGQPIMSVRGREQHKAAMI EALRRAKFKFPGRQKIYVSSKWGFTKWERDEYTTMRAEGKLIPDGVNVQYRPNKGPLQAW KDRQKVTKILGRTGSQGQCTQVRVEFLDDSNRSIIRNVKGPVREGDILTLLESEREARRL RMTKGTSSFGKRHNKTHCLCRRCGRRSYHIQKKLCARCGYPYARQRHFNWSEKAKRRRTT GTGRMRHLKIVQRKFRNGFREGTQPKPRQRVVEDRATAKELDQWVEQLNDCKQLTESQVK TLCEKAKEILSKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGRSPDTNYLFMGDYVDR GYYSVETVSLLVALKVRYKDRITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGW GISP-------------------------------------------------------- ----------------------------------------XXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXX---------------------FVAKPTKNADGTLSLMNWECAIPGKKGTPWEGGLY KLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSLLDEEKDWRPAVTIKQILLGIQE LLNEPNIKDPAQAEAYTIYCQNKVEYERRVKEQAMRFRDQS-GKSSKMLQHINYRMRCTL QDGRMFIGTFLAFDKHMNLILGDCDEFRKLKPKSSKAKEEKRVLGLVLLRGENLVSMTVE GPPPADDG-SRVPLPGGVGGPGMGRSAGRGMPHGPGLQGPVRGIGGPGHQHMQPG----R GG--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXLSFAENFALSGAAAVISKTAAAPIERVKLLVQNQDEMIKAGRLSEPYKGVIDCTM RTFRTEGVLPFWRGNLANCLRYFPTQALNFAFKDQIKKAFKQNRSDSYAVKFSKNVASGG AAGALSLCFVYSLDYARTRLANDAKGA--RQFNGLIDVYRKTLKSDGFVGLYRGFVISCV GIIVYRGCYFGFYDTLKPIVLGDDANVVLAFMLGYVVTISAGLVSYPIDTIRRRMM---- ---------------------------------------------------------XXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX VRLPPEVNRILYVRNLPYKITAEEMYDIFGKYGPIRQIRVGNTPETKGTAFVVYEDIFDA KNACDHLSGFNVCNRYLVVLYYQSSKAFKKVDTEKKQDDLDKMKQKYGLSTPDLRXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMQNEAGEFVDM YFPRKCSASNRIIGAKDHASIQINIADVDPTTGRMTGQYKTYAICGNIRRMGESDDSLVR LSKKDGIVAKMARGPKKHLKRLHAPXHWMLDKLSGVFAPKPSPGPHKLRECLPLMVFLRN RLKYALTYDECKKILNQRLIRVDGKVRTDNTYPAGFMDVITIQKTSENFRLIYDVKGRFA VHRITPEEAKYKLCKVKRVQLGPKGVPYCVTHDGRTIRYPDPNIKVNDSLRVXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXTDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYA NNSNYKNDTMIRKEAYVHKSVMEELKRIIEDSEVMQEDDQLWPPPDRVGRQELEIVIGDE HISFTTSKIGSLVDVNQSKDPEGLRTFYYLVQDLKCLVFSLIGLHFKIKPIMVVQKKSKK AIESINSRLQLVMKSGKYVLGYKQTLKTLRQGKAKLVIIANNTPPLRKSEIEYYAMLAKT GVHHYNGNNIELGTACGKYFRVTTLSITDPGDSDIIRSMPASXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXMGDRYNIHSQLEHLQSKYIGTGHADTNKWEWT TNQHRDSCASYQGHFDMLNYFAIVENEAKARVKFNLLERMLQPCGPPPERPEDXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMKLNVSYPATGCQKLFEVDDEKKLRAFYEKRMSQEVGGESLGDEWKGYIFRITGGND KQGFPMKQGVLTAGRVRLLLSKGHSCYRPRRSGERKRKSVRGCIVDSNLSVLSLVIVKKG ENEIPGLTDNTIPRRLGPKRASKIRKLFNLAKADDVRQYVVRRPLPARTKAPKIQRLVTP LVLQRRRHRNSLKRKRAAKKRDEAAEYAKLLAMRIKGAKERKAERKRSAS---KVKAKEL RGKKKEDLLKQLNELKQELSSLRVAKVTGGAASKLSKIHLVRKSIARVLTVINQTQKENL RKFYKPKDLRPKKTRAMRKALTKTELAMKTKKQQRKERLYSVRKYAVKKEKKGPKVTDKV FFDIEIGGEKAGRIVIGLFGKSVPKTAKNFKTLAEGTETYKGSKFHRVIKDFMIQGGDFT RGDGTGGESIYFDDENFKLKHYGSGWLSMANSGKNTNGSQFFITTKKTEWLDGRHVVFGV VVEGMKVVRKIENTKTSGDKPKKDVVIADCGSLPVDKPFSVPQADVKEKKKKLSLKFTVD CTHPVEDGIMDAASFEKFLHERVKVKGKTNNFKSKVAVTSDIPFSKRYLKYLTKKYLKKN NLRDWLRVVASSSDSYELRYFQINNEDDDDEE--XXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXMAATLKPYLTAVRNTLTAAMCLENFNSQVVERHNKPEVEVRSS KELLLTPVVISRNEKEKVLIEASVNSLRISIAVKQADEIEKILCHKFMRFMMMRAENFII LRRKPVEGYDISFLVTNFHTEQMFKHKLVDFIIQFMEEIDKEISEMKLAVNSRARISAEE FLKRFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGAEKTHINIVVI GHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITI DIALWKFETTKYYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQT REHALLAFTLGVKQMIIGVNKMDSTEPPYSAARFEEIKKEVTGYIKKIGYNPDEVAFVPI SGWHGDNMLKMPWFKGWETKNGKCLFDALDNIDPPSRPTEKPLRLPLQDVYKIGGIGTVP VGRVETXILXPGMVVKFA------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPKQ IMEIKDFLLTARRKDAKSVKIKKNVKFKVRCSRYLYTLVIQDREKAEKLKQSLPPGLSVQ ELKMSKLSKDGVHDAVEAILKKRRRFTESVELQISLKNYDPQKDKRFSGTVKLRHIPRPK LRVCILGDQQHIDEAKANDIPHMDVDALKKLNKNKKLVKKLAKKHDAFLASESLIKQIPR ILGPGLNKAGKFPTLLSHGESMTGKIDEVKATIKFQMKKVLCLAVAIGHVKMTEDQLANN VILSVNFLVSLLKKNWQNVRALYIKSTMGPVQRIYXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---YSFDG LVVFGLLVVCTTAYMRRV-PKLFLSEKKGFLGIFYKGAVIGTRLHIPVAISCVTMALYVL VI-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXATMAK PKGEMTPEELAAREQEEFNTGPLSVLTQSXKNNTQVLINCRNNKKLLARVKAFDRHCNMV LENVKEMWTETPKT----------------------------------PIVIDGRGHLLG RLAAVVAKTILQGQRVVVVRCEGINISGNFYRNKLKYLAYLRKRMNTNPSRGPYHFRAPS KVLWRTIRGMLPHKLPRGEEALSRLKTFEGIPPPYDKEKRLVVPSALKVLRLKPRKKFCN LGRISHETGWKYQDVISALKAKRKVKSNIRYKQKKADLKLREQAKRL------------X XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRRLQLTLALLKPDVTPH EIKDVILQNGFFFVRSKKFHMARDRAEQFYAEHVGKPFFNRLSTFMCSGPFSAHILGRVN AIKTWREIMGPTRVYSTVYSHPNSLRAIYGLTNTRNSVHGSDSPTSAEREIKFFFP---- -------------------------------------------------------MFEAR LVQGSLLKKVLESVKDLLTDASWDCTGNGISLQAMDSSHVSLVSLSLLSEGFDTFRCDRN LSMGINLGSMSKILRCAGNDDAITIKAGDDADTVTFMFESTNGEKVSDYEMKLMNIDSEH LGIPETDYNCVVKMPSAEFQRVCRDLSQIGESVVICCTKEGVKFSATGDLGTGNIKLAQS ANVDKEEEAVIIEMQEAVTPYFALRYLN-------------------------------- ----------------KTTCAYHTSSSAAKGRIVAVIGAVVDVQFDEELPPMLNALEVQG RDTRLVLEVAQHLGENTVRTIAMDGTEGLVRGQPVQDMKAPIKIPVGPETLGRIMNVIGE PIDERGPIPAKHFSGIHQEAPEFTEMSVEQEILETGIKVVDLLAPYSKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVISLKDDTSKVSLVYG QMNEPPGA---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------MLMPKKNRIAIYEHLFKEGVLVAKKDFYAPKHPELDVPNLQVI KALTSLKSRGYVKEQFAWRHFYWYVTNEGIQYLRDFLHLPPEIVPATLKRQAGGEDRAAY RRGGGGDKKSDVGAGATXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMATKTKVAKVDEENNHDGDKGQQ EAVEQIDEVQNEIDRLNEMASEEILKVEQKYNKLRQPHFSKRSELIAKIPNFWVTAFVNH PQVSALLNEDDEEALQFLTKVEVQEFDDIKSGYKINFHFDSNPYFENDVLTKEFHLKTTD CTSIKWKPGKDLTQSSNKRSHVEMDTFFAWFLDTGDAGADELGEVIKDDIWPNPLQYYLA SEIDEEGAEDEEIEDEEKKLTKEEELLLQDFSRNVTTKSSALFYGNAFIVSAIPIWLFWR MHQMDPYILFLVGTLISTYLISFAYKNVKFLLKHKIAVKIEDAVSKEVSKMIADDKKISK REKDERILWKKNEVADYEATTFSIFYNNALFLVLVVGISFYVLRSFTAPFNYIMTLGSAS GLIALFSTSTKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDVEPELLDYDE-EEQETKDVKGTYVSIHSS GFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILSMDVLCQAKSGMGKTAVFVLATLQ QLEPVDGQVSVLVLCHTRELAFQISKEYERFSKYMNSIKAAVFFGGMPIKKDEEVLKKNC PHIVVGTPGRILALGKSLNLKNVKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMF SATLSKDIRPVCKKFMQDPMEVYVDDDSXLTL---------------------------- ------------------------------------------------------------ ----------------------------------------------------XXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--DT VQSVVKKFYNEYMETTSKKLKIIDAYLLYILLTGIMQFGYCVLVGTFPFNSFLSGFISCV GSFVLAVCLRVQVNPQNKNEFHGIAPERAFADFIFAHIILHLVVINFIGSLASPSQLLPL ELVDKCIGSRIHIIMKNDKEIVGTLLGFDDFVNMVIEDVIEYESTPEGRRITKLDQILLN GNNITMLVPGGEGPEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXMGKFMKPGKVVLVLGGRYAGRKAIIVKNYDDGTTDKQYGHALVA GIDRYPRKVTKKMGKKKLKQRSKVKAFIRCYNYNHLMPTRYSVVNLDKQVVNKDAFRDPA LRRKARREAKMKFEEKYKTGKNKWFFQKLRFERSFIMVKPDGVQRGIVGEIIKRFEQKGF KLVAMKFMQASEEHLKKHYIDLASKPFYPGLCKYMSSGPVVPMVWEGGVVKTGRVMLGET DPAKSLPGTIRGDFCIEIGRNICHGSDSVQSAEKEIALWFKPEELTNWEPCEKPWVYE-- ----------------KPKRRVLKGVHDKRXRETRTSVHFRRPRTLRLPRAPKYTRKSVH RRLQLDQRKIIKYPLTTESAMKKIEDNNTLDFLDDERCNKPKIKFAVKKLYDINVDKVNT LNRPDGEKKAYMRLAPDYD-----------MVTKQRMRLANEKHSKNVHNRGNVPKTLKS AEEKLPVGPWLLGLFVFVVCGSAIFQIIQSIRMVKIKGWTAVATWRWVADDENCGICRMP FDGCCPDCKLPGDDCPLVWGQCTHCFHIHYIVKWLNSQQVQQQCPMCRRDWKFKEXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXQPTIFSKIIDKSIPADIIYEDDKSLAFRDVDPVSPIHFLVIPR KPIPGISADQALLGHLLLIAKKVADQAEGYRIVINNGKNGAQSAYHLHLHVMGGRQMDWP PMGGLISYFSGLFGSKERRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVVYKN LKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSMDRDRIGISKQELVSMLE-------- ------------------------------------------------------------ -XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 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YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGEPINEYVDTAVRHVLLRQ GVLGIKVKIMLPWDPSGK-------------------------------------GRGGS AGGKFRISLALPVGAVINCADNTGAKNLFVIAVSGIKGRLNRLPAAGTGDMFVAT----- ------------------------------------------------------------ ----------RKGKTVVVSLGPTVDDGESVFGVAHIFASFNDTFVHVTDLSGKETIARIT GGMKVKADRDEASPYAAMLAAQDVAEKCKSLNITALHIKLRATGGNKTKTPGPGAQS--- ----------------------------------MGKPSGLRTARKLRNHRRDQKWHDKD YKKSHLGTRWKANPFAGASHAKGIVIEKVGVEAKQPNSAIRKCVR--------------- ---------------------------------------------------------EGT VTIRTRKFLTNRLLSRRQMVVDVIHPGRATVSKKDVREKLATMFKATSDIIFAFGFRTQF GGGKSTGFALIYDSLDYAKKFEPTYRQARHGARKQRKERKNRQKKVRGTKKAKVGS--RV PLVSSKTYTTPRRPFEKDRLDQELKLIGQYGLRNKREVWRVRFTLAKIRKAARELLTLDE KDQRRLFEGNALLRRLVRIGVLEEGKMKLDFVLGLRLEDF-----QTQVFKLGLAKSIHH ARVLIRQRHIRVRKQVVNIPSFIVRLDSQ------------------------------- --MGN-FLGLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDKERIGEAREELNRMLNEDELRD AVLLVFANKQDLPNAMTAADLTDKLALHSLRSRNWYIQATCATSGDGLYEGLDWLSQQLK NAKMPLAKDLLHPSLEEERDKCKLKRLVQSP----------------------------- ---------------------------MVRMNVLADALRSICNAEKRGKRQVLIRPCSKV IVRFLTVMMKHGYIDEFEIIDDHRAGKIVVNLTGRVNKCGVISPRFD------------- -------------------------------------MGRMHAPGKGISQSALPYRRSVP TWLKLTPDDVKEQIYKLAKKGLTPSQIGVRLRDSHGVAQVRFVTGNKILRILKGKGLAPT IPEDLYHLIKKAVTIRKHMERNRKDKDSKFRLI--------------------------- --------VADIPEVKLFGQWSSDEVQVIDISLSDYIAVKEKHAKYLPHSAGRYQVKRFR KGQCPIVERLTSSLMMHGRNNGKKIMTGRIVKHSFEIIHLLSG----------------- ------------------------------------------------------------ ----------------------MSDQMTLRGTLCGHGGWVTQIATTPQYPDMILSSSRDK SLIMWKLTRDTNYGVPQRSLKGHSHFVSDVVMSSDGQFALSGSWDHTLRLWDLSTGSSTR QFVGHTKDVLSVAFSADNRQIVSGSRDKTINLWNTLAVCKYTIEDGHTEWASCVRFSPNT QNAIIVSCGWDKLVKVWNLTNCKLKTNHIGHSGYLNCVTVSPDGSLCASGGKDKLAMLWD LNEGKH------------------------------------------------------ ---------------------------------------KLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKVVEVDGQQSMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKLARSFQCSFLETSAKNK VNVNQIFYELVRLINKKDPQQ-----K-MTEHINLKVNGNDGSVVHFKIKKHTPLRKLMS AYCERTGVQMSAMRFRFDGQPINEDDTPLKLDMDDGDSIDVFQQQTGGMATLPMNPKPFL HGLTGKPVMVKLKWGMEYKGYLVSVDTYMNLQLANTEEFIENVMTGNLGEVLVRCNNVLY IRGVEEEEEDGEARDMSDAEGDDTHG--VHAGSMDILTALQEVLKLSISHDGLARGLREC AKALDQRKAHLCVLANNCDEPMYVHLVE-------------------------------- ------------------------------------------------------------ --------------------------------------DYDRLRPLSYPDTDVILMCFSI DSPDSLENIPEKWTPEVRHFCPNVPIILVGNKKDLRNDENTKRELMKMKQEPVRPEEGRT MAEKINAYFYLECSAKTKDGVRDVFETATRAALQMTKKKKPIXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFSANAKIVKPGGEKPDEFEASISQ ALLDLEMNSDLKAQLRELYITGAKEIEISGKKAILISVPVPQLRTYQKILVRLVRELEKK YSGKHVVFIAQRRILPKPTRKTRRKNKQKRPRSRTLTAVHDSMLEDIVFPAEIVGKRIRI KLDGARLFKVHLDKQNQTNVEHKLETFSTVYKKLTGKDVAFEFPE---DRGGFRGGFGGG GRGRGRGRGRGKESEREWIPVTKLGRLVKDGKIKTLEDIYLFSLPIKECEIVDNFLGSAL KDEVLKIKPVQKQTRAGQRTRFKAFVAIGDYNGHIGLGVKCSKEVATAIRGAIILAKLSV IPVRRGYWGNKIGK---------------------------------------------- -----------------------------------------------------MSGNLDV LALKAEDVQKFLVCSVHLCSDNIDFQMKQYIYKRKADGTYIINLRKTWEKLLLAARAIAA IENPADVCVISSRSYGQRGVLKFASATGATPVAGRFTPGTFTNQIQEAFREPRLLVVTDP RSDHQPIIEASYVNIPTIALCNTDSPLRYVDIAIPCNNKGSHSIGLMWWMLAREVLRLRG TISRESPWDVMVDLYFYRDPEEVEK----------------------------------- -------MKFNKNVSASRRKNRKRHFSAPSHIRRKIMSSPLSKDLRQK------------ ------------------------------------------------------------ ------------------------SPSSTNVGSTVRQRKTVASGAGGAGMWRFYTEDSPG IKVGPVPVLVISLLFIASVFMLHIWGKYTR-KKETKKKSAMTEVVTREYTINIHKRIHGI GFKRRAPRAIKAIRKFAEKQMGTNDVRIDTRLNKHMWSNGV------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------DNFLMGIGRHCNKVYLIDF GLAKKFRDNRTRCHISYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRGT LPWQGLKAATKKQKYDKISEKKMSTPVEILCKGYPAEFAMYLNYCRGLKFDEAPDYMYLR QLFRILFRTLNHNYDYVFDWTILKQRAASGMNAEKLKARIGGKGTARRKKKVVHRTATTD DKKLQTSLKKLAVNTIPGIEEVNMIKDDGQVIHFNNPKVQASLQANTFAVTGHAETKPIT EMLPGILNQLGTDSLGQLKKMASHVGEIDDDDDEVPDLVENFDEPSRGEMVRYSAKPDNP AKSALARGSHLRVHFKNTREAAQAIKHMHLRRALRFLKNVKDMKECVPFRRFNGGVGRCA QAKNWGT----------------------------------------------------- ------------------------------------------------KKIGPKPELTEE QKQEIREAFDLFDTDGVGTIDAKELKVAMRALGFEPKKEEIKKMISEIDKDGTGTIDFGD FLQLMTQKMTEKDSREEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEADRD GDGEINEGEFLRIMKKTSLYMGISRDKWHKRRKTSGRQNPIRKKRKFELGRPASNTKLGP KRIHTVRTRGGNKKYRALRLDTGCFSWGSEAQTRKTR----------------------- ------------------------------------------------------------ ------------------------------------------------SLIVPEKFLHIL RVMNTNIDGARKVPFALTAIKGVGRRFAMIACKKADIDVNLRAGELSEEEVDKLITIISN PRQYKIPDWFLNRQKDTVDGKYSQVLSNLLDNKLREDLERLKKIRAHRGLRHYWGLRVRG QHTKTTGRRGRTVGVSKKK-SGSDSDTDD-ARDLEEIAQAAGIPEELVSKAKQSRSEKKA RKAMSKLGLKQVAGVNRVTIRKSKNILFVINRPDVYRSPAGDTFIVFGEAKIEDLSQAAQ LRAVDQFKTEEEVDETGVEAKEVELVMSQANVSKNKAIKALKNNNNDIVNAIMXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMYWEY KEEHPFEKRRGEGEKIRKKYPDRVPVIVEKARKARVGDLDKKKYLVPSDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGALYQEHHDEDFFLYIAYSDESVYGMRELRISKL CLNICVGESGDRLTRASKVLEQLTGQTPVSSKARYTVRSFGIKRNEKIAVHCTVRGAKAE ELLERGLKVREYELRRNNFSDT---------------KYDPGIGIYGMDFFVVLGRPGFR VSQ----------------------------------------------------EIAKP ERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGIS PIVTSGLIMQLLAGAKIIEVGDTPRDRALFNGAQKLFGMVITIGQSIVYVMTGMYGDPAE IGAGVCLIIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVN TGRGTEFEGAIIALFHLLATRSDKVRALREAFYRQNLPNLMNLLATVLVFAIVIYFQGFR VDLPIKSARFRGQFSSYPIKLFYTSNIPIILQSALVSNLYVISQMLATKFSGNFLINLLG VWADVGGGGPARSYPIGGLCYYLSPPETLQHVLEDPIHALLYIIFMLGSCAFFSKTWIEV SGSSAKDVAKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIG SGTGILLAVTIIYQYFEIFLKEQSEQGGMSTLLFXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRVIRSQRKGAGS VFRAHTHKRKGAARLRAVDFAERHGYIKGVIKDIIHDPGRGAPLAKVVFRDPYRYKLKHE LFVAAEGMYTGQFVYCGKKATLQVGNILPVGSMPEGTIVCCMEEKTGDRGRIAKASGNYS TVISHNPDTKKSRVKLPSGAKKV------------------------------------- ------------------------------------------------------------ -XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRRPARCYRYCKNKPYPKSRFCRGVPDP KIRIFDLGRKKARVEDFPLCVHLVSDEYEQLSAEALEAARICANKYLVKSCGKDAFHMRI RPHPFHVVRINKMLSCAGADRLQTGMRGAFGKPQGLVARVNIGQPLISVRARDQHKD--- --------------------KWGFTKWEREDYETLKESGHLVPDGVIVESESP------- ----KVTKVLGRTGSQGQCTQVMVEFLDDSNRSIIRNVKGPIREGDILTLVESEREARRL RXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMVDDRSAAKELDQWIEQLNECRQLSENQVK TLCEKSKEILTKESNVQDVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDR GYYSVETVTLLVALKVRFKERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDNQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHTNSLTLVARAHQLVMEGYNWCHDQNVVTIFSAPNYCYRC GNQAALMELDDALKYSFLQFDPAPRRGEPHVTRRTPDYFLMGAYKYMQELYRKKQCDVLR FLLRIRCWQYRQLASVHRCSRPTRPDKARRLGYRAKQGIVIYRCRVRRGGRKRPVPKGAT YGKPVNQGVNQLKNQRSHQAIAEERIGRKCKGLRVLNSYWVAQDSTYKYYEVICIDPFHK AIRRDPKINWICAASKKHREMRGLTSASRKSRGLGKGHKFNNTIGGSRRANWKKHNSLSL RRKRGIALGRLMEERKAWRKDHPFGFVAKPAKNQDGTLNLMNWECGIPGKKGTPWDFGLF KLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSLLDEEKDWRPAVTIKQILLGIQE LLNEPNIRDPAQAEAYTIYCQNRVEYERRIREQALKFKDPS-GKSSKMLSYINFRMRCTL QDGRTFIGTFKAFDKHMNVILGDCAEFRKTKPRKGSNKEEKRDLGLVLLRGENLVSMTVE GPPPMEESGGRVPLPGA--GPGVGRAAGRGV--GGGLQGPPRGVGGPSYAAMQPQ----- ----VEIPTFKLVLVGDGGVGKTTFVKRHLTGEFEKKYVATLGVEVHPLNFFTSRGQIRF NVWDTAGQEKFGGLRDGYYIQGQSAIIMFDVTSRITYKNVPNWHRDLVRVCENIPIVLCG NKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDINLEFVAMPA LQPPEITMDPNLKLQYEQELKEAQETALPDDDDDL--GGKDYYVHKIEDLQLTVSEKTQN LRRLEAQRNELNAKVRMLREELQLLQEQGSYVGEVVKAMDKKKVLVKVHPEGKFVVDLDK NIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEI KEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ KFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRLESGSGGDSEVQRTMLELLNQLD GFEPTQNIKVIMATNRIDILDSALLRPGRIDRKIEFPAPNEDARADILKIHSRKMNLTRG INLRKIAEMMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFELAVAKVMQKDSEKNMAI TKQWKLGFAESFALSGAAAIISKTAAAPIERVKLLVQNQDEMLKSGRLDKPYGGVIDCTT RTMKSEGFGSFWRGNLANCIRYFPTQALNFAFKDQIKAAFKSSKDEGYAMKFSKNIASGG AAGAMSLCFVYSLDYARTRLANDTKSSKKRQFNGLIDVYKKTIATDGIVGLYRGFVISCV GIVVYRGFYFGLFDTLKPILLGDSANFAASFALGYV------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----GGDVPDTNYLFMGDFVDRGFFSVETFLLLLALKVRYPDRITLIRGNHESRQITQV YGFYDECLRKYGSVIVWRYCTEIFDYLSLSAIIDNRILCVHGGLSPSIQSLDQIRAIDRK QEVPHDGPMCDLLWSDPEDTHGWGVSPRGAGYLFGSDVVATFNADNKVDLICRAHQLVME GYKWHFGETVLTVWSAPNYCYRCGNVAAILELDEECSRDFTIFEAAPQESRGRPQADYFL VRLPPEVNRILYIRNLPYKITAEEMYDIFGKYGAIRQIRVGTTTETKGTAFVVYEDIFDA KNACDHLSGFNVCNRYLVVLYYQSNKAFKKMDVEQTKEEMNKMKQKYGLSTPE--MSIGV PIKVLHEAEGHIVTCETKTGEVYRGKLVEAEDNMNCQLSNISVTYRDGRVSQLENVYIRG SKIRFLILPDMLKNAPMFKKVGAGRGKSAILRAAARGRGRGGPP-GRGGXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXMARGPKKHLKRLNAPKHWMLDKLGGVFAPRPSTGPHKLRECLPLMIFLRN RLKYALTYSECKKILNQRLIKVDGAVRTDNTYPAGFMDVITIEKTGEFFRLIYDVKGRFT VHRITKEESAYKLCKIKKVSVAPKGVPYVTTHDARTIRYPDPLIKSNDTVKV-------- -----------------------------------IGVEFATRSIQVDGKXIKAQIWDTA GQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADNNIVIMLVGNKSDL RHLRAVPTDEARTFSEKNNLSFIETSALDSTNVETAFQNILTEIYRIVSQKQIRDSPDDG PVTTIKVAPTDIPNEKKIPCCNMSDRYDRAITVFSPDGHLFQVEYAQEAVKKGATVVGVR GKNIICLGVEKKAVANLQDDRTVRKIAILDENVVMAFAGLTADARVLIQRARVECQSHKL TVEEPVTAKYIARHIAELKQKYTQSNGRRPFGLSTLIAGFDNQCHLFLTDPSGTYHEWKA NAIGKNDKTVREKLEQKY-PKIETEEECINLVIEALQEVTQGGSECMEIVTIIPSQPIRF LTQSEIQVKIQAKKDAEEEEAAKEKK---SGGGDKKDDKDKKKKYEPPVPTRVGRKKKS- KGPEEANKLPKVTPHTRCRLKLLKLERIKDYLLMEEEFIRNQERLKPQEEKQEEERSKVD DLRGTPMSVGSLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDQLEPGCSVLLNHKVHAVV GVLGDDTDPMVTVMKLEKAPQETYADIGGLDSQIQEIKESVELPLTHPEYYEEMGIKPPK GVILYGQPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPS IVF-------------SNSGGEREIQRTMLELLNQLDGFDSKGDVKVIMATNRIETLDPA LIRPGRIDRKIEFPLPDEKTKKRIFSIHTNRMTLSDDVNLDEYVLAKDDLSGADIKAICT EAGLLALRERRMKVTNEDFKKSKDNVLYRKNEGVPEGLYLERKPYSPFKKSDKADYALAR VDDLVNWARKSSLWPLTFGLACCAVEMMHFAAPRYDMDRFGVVFRASPRQADVIIVAGTL TNKMAPALRKVYDQMPEPRWVISMGSCANGGGYYHYSYSVVRGCDRIIPVDIYVPGCPPS AEALLYGVLQLQKKIKRMKIMQSWYRKTEFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYA NNSNYKNDTMIRKEAYVHKAILDELKRIISDSEIMEEDDNLWPPPDRVGRQELEIVIGDE HISFTTSKIGSLVDVNQSKDPEGLRTFYYLVQDLKCLVFSLISLHFKIKPIMVAQKKAKK SMESINYRLALVMKSGKYCLGYKQTLKSLRQGKAKLIIIA-------------------- -------------------------------------------------------VGKSA LTIQLIQNHFVEEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGF LCVFAVNNSKSFEDINQFREQIKRVKDADEVPMVLVGNKVDLSTRYVEPKAGMNLAESYG IPYIETSAKTRLGVDDAFYKLVREIRKYMSDRYNIHSQLEHLQSKYIGTGHADTTKWEWL TNQHRDSYASYMGHPDQLSFFAIVENEAKARVRFNLMERMLQPCGPPPERPEDMKVDVCA FSGFKIYPGHGKRVVRSDGKAYQYINGKCAKAHLAKRNPRKVSWTVLYRRKNRKGITEEI SKKKTRRTAKFTRAV--------------------------------------------- ---MKLNISFPATGCQKLIEVDDDRKLRIFYDKRISAEVQADALGEEWNGYVVRISGGND KQGFPMKQGVLTANRARLLLSVGHSCYRPRRSGERKRKSVRGCIVDANLSVINLVIVKKG EGEIPGLTDTTIPRRLGPKRASKIRRLFNLSKEDDVTAYVIRRPLPPRTKAPKIQRLITP VVLQR------------------------------------------------KVKAKEL RGKKKEELHKQLDELKTELSQLRVAKVTGGSQPKLSKIHAVRKSIARVLTV--------- ----------------------------------------------------GPKVTDEV FFDITIDGEDVGRIVIGLFGSTVPKTAKNFKQLAEGVEGYEGSKFHRVIKDFMIQGGDFT RGDGTGGKSIYFNDENWKLNHYGAGWLSMANSGKNTNGSQFFITTVKTQWLDGRHVVFGK VVKGMDVVRKIESTKTKGDKP---------------------------KKKKTLLKFVVD CTLPVEDGIMEVAGFEEFLKTRVKVAGKTNNFKSKIIVSSDIPFSKRYLKYLTKKYLKKF TLRDW------------------------------------DEDFPGNCEGPDAVFVKLV SSDSHEFIVKRKHALTSGTIKAMLSGPGQFAENETNVINFREIPSHVLQKVCMYFTYKDK YTNSSTEIPEFPISPEIALELLMAANFLDCHKIIRFSEVQEHDNSKSCWMIIHNKVYDVT NFFDEHPGGDGVLLENAGKYATKEFEDIGHSSDAVELLAKYLVGVLHVDDH--------- --------------MSYMLAHLHNGWQVDQAILSEEDRVVVIRFGHDWDPTCMIFDETLY QVAERCKHYATFYLVDTTEVPDFNKMYELYDPCTVMFFYRNKHIMIDLGTGNNNKINWPM ENTQEFIDILETIYRGARKGRGLVISPKDYSTKYRYKRLQKQLEFLVVQEDYIKDEQRNL KKEYLHAQEEVKRIQSVPLVIGQFLEAVDQNTGIVASTTGSNYYARILSTIDRELLKPSA SVALHKHSNALVDVLPPEADSSITMLGSDEKPDISYADIGGMDIQKQEVREAVELPLTHF ELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTASFIRVVGSEFVQKYLGEGPRMVR DVFRLAKENSPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTINVKVI MATNRADTLDPALLRPGRLDRKIEFPMPDRRQKRLIFATITGKMNLSDEVDLEDYVARPD KISGADINAICQEAGMQAVRENRYVVLVKDFEKGYKNNIKKDETEHEFYKXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX--------------------------------------------- ------------------------------KTATFSISILQGLDIQVRETQALVLSPTRE LATQIQKVIQALGDYMSVQCHACIGGTNVGEDIRKLDYGQHVVSGTPGRVFDMIKRRNLR TRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVILISATLPHEILEMTNKFMTNPI RILVKRDELTLEGIKQFFVAVEKEEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKM REANFTVSSMHGDMPQKERDAIMKEFRSGASRVLITTDVWARGLDVQQVSLVINYDLPNN RELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------TIFNPWLIIGGVASSVCNQDEFI MQDSAVIGDVLVLTKPLGTQVAVTAHQWLEVPDKWNRIKLVVNQEDVVKAYFRAMSSMER LNRTAARLMHKYNAHGSTDITGFGLLGHASNMAAVQKNEVGFVIHNLPVIAKMASVSKAC SSLFGLLQGYSAETSGGLLIALPREQAAAFVKEIEQCVGQQSWIIGIVEKGNRTARIIDK PRVIEVPAKDRE-----------FLVHIDAHAEECFFDRVTSGTKLSLMFEVAEGGFLDV DVKITGPDEKTIYSGERETNGKYTFAAHMDGVYKYCFGNKMSTMTPKTVMFSVDIGEKPK AHQNKLEEMIGELSQSLTGVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMT LGQIYYLKRFFEVRRVVMAATLKPYLYAVRHTLTAALCLENFSSQVVERHNKPEVEVRTS KELLLNPVVISRNEKEKVLIEASINSLRISIAIKQADIVEKILCRKFMRFMMMRAESFHV LRRKPVDGYDISFLITNFHSEQMYKHKLVDFIITFMEEIDKEINDIKLAMNARARISAEE FLKRFSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLV TMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPNTFKTLDSWRDEFLIQASPRDPEN FPFVVIGNKIDLENRAVPTKRAQTWCHSKGEIPYFETSAKEAINVEQAFQTVAKNALAQE TNAELYNEFPDQIKLTNDQNKESCACTVPYDSRFPHQNQTRACWQNFIDYQRCVKVDD-E ICTYFKRAYESICPNDWSERWIEQIENGNFAGKIMPDHLGDDRRKIKDEDPEEIPIKVLD EEDIALLKSYGAGMYSSTIKKTEDDIQSTLKRVNELTGIKESDTGLAHPALWDLAADKNT LQSEQPLQVARCTKIINADSDDPKYIINVKQFAKFVVDLGDQVNATDIEEGMRVGVDRNK YQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPEKFVNLGI EPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMART KKACIIFFDEVDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDT LDPALMRPGRLDRKVEFGLPDLEGRTHIFKIHARSMSVEKGIRYELLARLCPNSTGAEIR SVCTEAGMFAIRSRRKVATEKDFLDAVNKVIKAYAKFSATPRYMTYN------HINIVVV GHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITI DIALWKFNTPKFAVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKDGQT REHALLAFTLGVKQLIVGVNKMDSTDPPYSEKRFGEIKKEVENYIKKVGYNPKAVAFVPI SGFHGDNMINMGWYKGWAVASGTTLLQALDSILPPSRPTSKPLRLPLQDVYKIG------ ----------------FAPGGITTEVKSVEMHHESLLEAVPGDNVGFNIKNVSVKEIKRG NVASNSKDDPAAECANFKAQVIVLNHPGQINPGYTPVLDCHTAHIACKFSELIEKIDRRS ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YAP SGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDNQIVTSSGDMTCA LWDIETGQQTTSFTGHTGDVMSLSLEPNMHTFVSGACDASAKLWDIRDGMCKQTFSGHES DINAITYFPTGLAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSRSGRLLFG GYDDFNCNIWDVLRQDRCGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLRVWNMSYAYLF KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES FRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSNSNMVIMLIGNKSDLEARR DVKKEEGEAFAREHGLIFMETSAKTAANVEEAFINTAKEIYQKIQDGVFDLNNEANGIKI GPQHSPTSPGASGGGNRQNG--------------------------------DKFYKDVL EVGELAKLAFFNDIVVGAVCCREDKSNGERRLYIMTLGTLAPYRRFGIGTVMLEHVLKIC EKDGNFNNVFLHVQVNNEGAIKFYEKFGFEIVEQKQNYYKRIEPADAYVLQKTF--MPKQ ISEIKDFLLTARRKDAKT------------------------------------------ ---MSKLNRELLHESLGIVLAKQRKFTETVELQIALKNYDPQKDKRFSGTIKLKHVPRPK LRVCLLGDQQHMDEAAANSVPCMDVEALKKLNKNKKLVKKLAKSYDAFLASDSIIKTIPR ILGPGLNKAGKFPTAI---------------------------------VNMTEEDLNAN ITLSINFLVSLLKKNWQNVRALYIKSTMGPVQKIY------------------------- ------ENEIRGLSLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKETLGWGENDRGVSFTFGAEVVAKFLNKHDLDLICRAHQVVEDGYEFFAKRQLVT LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLNTSRPLTPPRGAMKSK GKMMFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEISGTNVSTT YITCPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKGVRRRFRASNYQSTTRVKPF ICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDEL PPEFKLYLPVQKKMSELSIQNLADPFVDVEIVHIRIQQRNGRKTLTTIQGINSKYDLKKI AKNCKKEFNCNGTVVDHPEYGEVIQLTGDQRDKVEKWLLETTIKEQLKVHGFSAIFNFQS LLSVILLLICTCAYIRALAPRLLDKNKEGLLGIFWKCARIGERKSPYVALCCVAMAFSVL FLSSVKVCNGIARQLTRTLRQKQQVGTSFIVCRNVSTSSEVSSIMEERILGAVSANLEET GRVLSIGDGIARVYGLKNIQAEEMVEFSSGLKGMALNLEPDNVGIVVFGNDKLIKEGDIV ERTGAIVDVPVGEACLGRVVDALGNPIDGKGPLDTSERQRVGVKAPGIIPRTSVREPMQT GIKAVDSLVPIGRGQRELIIGDRQTGKTAVAIDTIINQKRFNDASDESKKLYCIYVAIGQ KRSTVAQIVKRLTDADAMRYTVVVSATASDAAPLQYLSPYSGCAMGEYFRDNGKHALIIF DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSPAFGGGSLTALPIIE TQAGDVSAYIPTNVISITDGQIFLETELFFKGIRPAINVGLSVSRVGSAAQMKAMKQVAG SMKLELAQYREVAAFAQFGSDLDAATQQLLNRGVRLTELLKQGQYVPMAVEDQVAVIYAG VRGHLDVIDPSRITEFETAYLSHIKSQHQ------------------------------- MESLYSIPFTVLEIPNLKLKRPSWVTQPSAMFVFAAVLVSYFLVTGGIIYDVIVEPPSVG QTTDERGNQKPVAFLPYRVNGQYIMEGLASSFLFTMGGIGFVVLDQTNKPATPKLNRILL FCIAFACIVISFFMCRVFMRMKLPMPKVKRSRKPPPDGWELIEPTLDELDQKMREAETDP HEGKRRVESLWPIFRLHHQKSRYIYDLFYRRKAISRELYDYCVKENIADQNLIAKWKKQG YENLCCLRCIQCRDTNFGTNCICRVPKNKLEEGKIVECVHCGCRGCSGEYAQVIKMLGNG RLEAKCFDGIQRLCHIRGKLRKKVWINATDIILIGLRDYQDKKADVILKYTPDEARNLKT YGELPETVNINEVEGDEIVFSGDEDILVRFLMKLSHETVTIELKNGTQVHGTVVGVDVCM NTHLKTVKMTLKNRDPVQLETLSIRGNNVRYFILPDSLPLDTLLIDDAPKARIKKSLMTK PKSEMTPEELQQREQEEFNTGPLSVLTQSVKNNTQVLINCRNNKKLLGRVKAFDRHCNMV LENVKEMWVETPRSGKGKKKSKPVNKDRYISKMFLRGDSVILVLRNPLPLLIDARGHLLG RLASIVAKTILQGQKVIVVRCEAMNISGSFYRNKLKYLSFLRKRMNTNPARGPFHFRAPS KIFWRVVRGMLPHKLHRGKEALDRLKVFEGIPSPHDKAKRLVVPAALKVLRLKQRRKFCD LGRLAAEVGWKYQKVISTL----------------------------------------E GDPEKGKKVFVQRCKQCHNVEQGGKHGTGPNLYGLWGRQTGQASGFDYTDANKKKAIIWG KETLFQYLENPKKYIPGTKMVFAGLKKKNERADLISYIESATK----------------- --------------------------------------------------IEVMVLAKSS AISSWRDMIGPTNALEAKNTHPDSLRAMYGTTSQKNGFHGSDSKESAAKEIRFFFPDSIV EPISIGMDTKDYLAKAVNPTLCKGLTELCKQKPSNPMLWLADWLLVNNPNKPKI-MFEAR LIQGSLLKKVLESVKDLLNEATWDCSSTGMALQAMDSSHVSLVSLLLRSDGFDTYRCDKN LSMGIKLPSMSKILKCSGNDDSITIKAGDDGDTVTFMFESPNGDKVSDYEMKLMDLDTEH LGIPETDYNAVVKMPSGEFQRICRDLSQIGESVVICCTKEGVKFSANGDLGTGNVKLAQT ANVDKEEEAVIIEMQEPCTLTFALQYLNFFTKATPLSSRVTLSMSPEVPLVVEYKIGEMG FVRYYLAPKIEDDADAQTLASIHSSNTLPTGRVVAVIGAVVDVQFDDELPPILNALEVEG RSPRLILEVAQHLGENSVRTIAMDGTEGLVRGQNCVDTGTPIRIPVGPETLGRIINVIGE PIDERGPVNSQHFAGIHAEAPEFVEMSVEQEILETGIKVVDLLAPYAKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVISLTDNTSKVSLVYG QMNEPPGARARVALTGLTVAEYFRDKEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTQKGSITSVQAIYVPADDLTDPAPSTTFAHLDATTVLSRGIS ELGIYPAVDPLDSISRILDPNIVGANHYNIARGVQKILQDYKSLQDIIAILGMDDLSEED KLTVA------------------------------------------------------- -----------------MLMPKKTRVEIYEHLFKEGVLVAKKDFHAPKHPELPILNLHVI KAMTSLKSRG-------------------------------------------------- -----------------MGQEQSSTPPKTIEELKESLTYTTEDLKKWYSSCLIDVNNGTM NRDQFKKAYFTLYSHGDCGALADHIFRVFDKNGDGNIDTKEFISYMSIFSKGSADDKLTA AFKVYDVNCNGLISRDEMLQIVESIYQLVENVENFDEDEATPELRVSKFIALMDKNGDGE LSLKEFKSGAKSCPTIIRILRND-MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNL TGLNEQVPHYRQALDMILDLEPDDDLDENPNQSDLIEQAAEMLYGLIHARYIMTNRGIAQ MIEKWQQGDFTYCLRVYCENQALLPIGLSDIPGEAMAKLYCPKCQDVYTPKSSRHHHTDG AYFGTGFPHMLYMVHPEYRPKRPTSQFVPRLYGFKIHASAYQLQYQAAANFKMAFANGKR MTNTKGYRRGTRYMFSRQFRHKGPMHLSKYLKIYKRGDIVDIKGDGAIQKGMPYKVYHGR TGRIFNVTKHAVGVIVNKRVRGKILAKRINLRIEHIKHSNCRLDFLNRVDKNEALKKAAK AIVHTKRVPQQPKEGHFVSTKFNKPQILVQQPYVFTA--------VSKPEPGMSMRELVD RGTDFVFMVELLKGLGLTASKIFQEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAICPAQAITIEAETRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEY STETHEELLYNKEKLLENGDKWEPEIQANLQADHLYR------------------DKEQQ EAIEHIDEVQNEIDRLNESASEEILKVEQKYNKLRQPYFSKRSDLIAKIPNFWVTAFINH PQVSALLNEEDEEALQYLTKVEVQEFEDIKSGYKINFHFDGNPYFENPVISKEFHLNSSK SSGITWKSGKDLTKKSSKRSHEE-DSFFSWFSDHGDAGADELGEVIKDDIWPNPLQYYLA SEIEEEDDDDDEDDDEEKKTTKEEELLLQDFSRHVSKKSNALFYGNALIVSALPVWLFWR VHHMDLKILFTIMTLVSTFFVSYAYKNVKFLLKHSISRKRDSAVTKEVLKKVSDIKSMSR EEKDERILWKKNEVADYEATTFSIFYNNAMFLVMLIVISFYLLSTFSPMYNYALTMASSA GLIALFSTSSQTTPGKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQT VCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNVDTFGKAKNWVKELQRQ ASPNIVIALAGNKADLRMIEFEEAQNYAEENSLLFMETSAKTGKSVEELFLAIA------ -------------YLASIFGTEKDKVNCSFYFKIGACRHGERCSRLHNKPTFSQTVLLLN LYINPQNTAQIVMTDMQAQEHFDEFFEEVFTELEDKYGEIDEMNVCDNLGDHLVGCVYVK FKYEEDAERAVESLNNRWFNKRPIVAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKP ISRELRHSLYGRSRRNR----------------------------MFLTRSEYDRGVNTF SPEGRLFQVEYAIEAVKHGETAMGIKTPEGVVLTVEKRCTSELIVPSSIEKIKEIDAHIG CATTGIQPDADTLVNRARLEAQNHWFTYNENMTVESVTQSVSNLALAFG-DDSSPSAMSR PFGVSLLFAGWDEKGPQLYHMDPSGTFIEYMAKAIGQGAEGANQSLKDIYPKTLLLNEAK KHSLKILKHVMENKMSNTNVEMATVTKDDQFSKITESELQEIISAI-------------- ------------------------------------------------------------ ----------------------------------------------------------PG YGCWLSGIDVSTQMLNQTYQEPFVAIVVDPIRTISAGKVNLGAFRTYPKGFKPPNEGPSE YQTIPLNKIEDFGVHCKQYYSLEVSYFKSSLDRKLLESLWNKYWINTLSSSNLLTNADYL TGQIFDLADKIESAEYALGKNSWLESKNEDKLGKATKDACKNTIEAMHGLMSQVLKNQIF NKV--------------------------------------------------------- -----MSAPKVRFMTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPD DPLANDVAEKWKSNEAEAIKNAKEWTRLYA------------------------------ ------------RAIVDCGFEHPSEVQHECIPQAILSMDILCQAKSGMGKTAVFVLATLQ QIEAVDGQVSVLVLCHTRELAFQISKEYERFSKYMGSAKVAVFFGGLPIKRDEDVLKKNC PHIVVGTPGRILALAKVLTLKHIKHFILDECDKMLEALDMRRDVQDIFRMTPHEKQVMMF SATLSKDIRPVCKKFMQDPMEVYVDDDSKLTLHGLQQHYLKLKDNEKNRKLFELLDVLEF NQVIIFVKSVQRCVALAQLLVEQNFPSIAIHRAMTQEERLSRYQQFKDFQKRILIATNLF GRGMDIERVNIVFNYDMAEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKVPPGYADIG KGAKDLFNKGFNYGGHKLEFKSQTANGSKFTTNLTNNVDSGKSDGFLETEYKVADRGLTF KEKWSTDNTLTTDLTVEDEFLKGLKIVFNSEFKPHTGYKHAKLKTGYKQEYINANCDIDL DFAGPVVHGAAVVGYKGWIAGYQMSFQKSKLTKNNFAIGNVGSDYALSATINDGSVITGS YSHKLSPVLEAAAQLSLTTGTNAVTVGXAGKYALDSDTIVRGKVNDKGQIGVSYQQDLRK GITLNLSALIEGQNFNAGGHKIGLGVDLAA-TAREKALVDYRKKLLEHKELEASLKQVRE QLKDLTKQYDKSENDLKALQSVGQIVGEVLKQLTEDKFIVKATNGPRYVVGCRRQIDKTK LKSGTRVALDMTTLTIMRYLPREVDPLVYNMSAEDPGDITYAQIGGLGEQIRELREVIEL PLLNPELFLRVGITPPKGCLLFGPPGTGKTLLARAVASQMNCNFLKVVSSAIVDKYIGES ARLIREMFGYARDHQPCIIFMDEIDAIRRFSEGTSADREIQRTLMELLNQMDGFDALGQV KMIMATNRPDTLDPALLRPGRLDRKIEIALPNEQARLEIMKIHAAPIAKTGEIDWEAVVK LSDDFNGADLRNVCTEAGMFAIRGERDYVIEEDFMKAVRKVAENKKLESKLDYKPVMPET LKSVVSRLIDDYSINTPIKLKIIDAYLTYIVLTGVVQFVFCCLVGTFPFNAFLSGFISCV GSFILGACLRIQVNPQNKNEFSGIGPERAFADFIFAHVVLHLVVMNFIGSLASPSQLLPL ELVDKCIGSRIHIIMKNDKEIVGTLLGFDDYVNMVIQEVTEYETTSEGRRVTKLDQILLN GNNITMLVPGGEGPEVIDHYENPRNVGSMDKSDKAVGTGLVGAPACGDVMKLQIKVDDDG KIIDAKFKTFGCGSAIASSSLATEWIKGKTITEAGTIKNSDIAKELCLPPVKLHCSLLAE EAIQAALKDYEKKS-MLVLVLGDLHIPHRKSSLPAKFKKLLVPGKIQHILCTGNLCTKES WDYMKTLASDVHVVRGDFDENMSYPEQKVVTVGQFRIGLCHGHQIVPWGDTESLSLVQRQ LDVDILITGHTHKFEAFEHENKFYINPGSATGAYHPVDSDISASFVLLDIQQSTVVAYVY QLIGEDVKVERIEYKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXELTFIMIKPDGVQRGLIGEIIKRFEQRGY KLRAIKMEQATKEHLECHYEDLRGKSFFDGLIKYMGSGPVCPMVWEGDAV---------- ------------------------------------------------------------ ----------------------------------------QKPKICELQQNPKYQRKSTP KRPYLDQFKIVKYPLTT------------------------------------------- ------------------------------MPSKQRMRLANDKASKNVLARGQVPKTLKS SDEKYPVGPWMLAFFLFVVCGSAIFQIIQSIRMVKIKGWTAVATWHWVANDDNCGICRMP FDGCCPDCKLPGDDCPLVWGECSHCFHIHCIVKWLNSQQVQQLCPMCRQEWKFKEMIRFI LIQNRAGKTRLAKWYMHFDDDEKQKLIEEVHAVVTIRDAKHTNFVEFRNFKIVYRRYAGL YFCICVDVIDNNLMYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYSVVDEMFLAGEIRE TSQTKVLKQLMMLNSLE-PTIFDKIIDKSIPAEILHEDDQCMAFKDINPCAPTHFLVIPK RRISQISSDASLLGHLMVTATKVAKDDNGYRVVINNGHDGLQSVYHLHLHIMGGRQMKWP PMGGLVSYFSSLFGSKERRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVTYKN LKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSMDRDRIGISKQELISMLEEDELKKAV LVVFANKQDIEGAMSVTEVANALGLSTLKNRKYQIFKTSAIKGDGLEEAMEWLATSLQSS KSLYFIINETEKKCFIEEIPDEVTIVGNYKVEMYDQNSNQYLPTMAGLGMHVEIKDPEDK VVLSRMYSSEGRFSITSHTAGEHSICLNSNSTAWFGRGQLRVHLDIQVGEHANDYPAIAA KEKLTELQLRVRQLLDQVDQITKEQNYQRYREERFRNTSESTNQRVLWWSIAQTGILLIT GFWQMRHLKGFFEAKKLVMFYHVQLEHEILLHPRYFGPNLMTVVKQKLFSEVEGICTGKW GFVIAVTTIDNIGAGMIEQGRGFVCYPVKYKAIVFRPMKGEVLDAVVTQVNKVGLFTEIG PLQCFISRHSIPADMEFDPSSNPPCYKTTDEDMVIQQDDDIRVRIVGTRIDATDIFAIGS LMDDYLGLV-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--KKTY DLLFKLLLIGDSGVGKTCLLFRFSDDAFNTTFISTIGIDFKIKTVELGGKKIKLQIWDTA GQERFHTITTSYYRGAMGIMLVYDITNAKSFDNISKWLRYIDEHASEDVEKMILGNKLDM EDKRQVPKDRGMQIAQEHDIPFKETSAKSNINVESAFMDLATAILNKMPQNEHIELHRKR YGRRLDYEEKKRKKEARAVHETAAKAKKLRGLRAKIYNKQRHAEKVQMKKTIKMHEERKT KQKKEDEVPEGAVPAYLLDREGQTRAKVLSNMIKQKRKEKAGKWDVPIPKVKGISEGEVF KVVTSGKRGKKSWKRMVTKATYVGEGFTRKPPKFERFIRPMGLRYKKAHITHPELKATFN LPIIGVKKNPTSPLYTSLGVITKGTVIEVNVSELGLVTTGGKVVWGKFAQVTNVPENDGC INGVLLVMAARPLISVYNEKAETTGKNITLPAVFKAPIRPDVVNFVHFQMLKNTRQPYAV SKKAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKIWRRWHRR INVNQKRYAICSAIAATGIPSLVMSKGHRIEETPEIPLVVSDNVQEFKKTKEAVTLLKKF KAWNDIEKVKSTRRFRAGKGKMRNRRRIQKRGPVVIYDQDNGICRSFRNIPGITLINVAH LNLLKIAPGGHVGRFCIWTESAFQKLDSIYGTWRKASTEKSKFNLPMPKMTNTDLARLLK SDEIQSVIREPIKTK--------------------------------------------- -----------------GSGEQELATKTLQIQSKRFYLDVKQNRRGRFIKIAEVGSGGKK SRLLLAMSTAAEFRDHLTEFSEHYASLGPPNPDNLPEDGKLKSETMAKDNRRYYLDLKEN QRGRFLRVS-SAGRRSQVLIPAQGMIEFRNGIKELLDEFGTDDHEGQGELPEPRSMRVEN KMFYFDVGQNRRGVFMRISETNFRTAVTIPEKSWSRLRDILNEFCDK--------KMKAQ INQSLVEEGERDRLKELLRERLIECGWRDQLKSQCKDVIRQYGSKNITLDDLVAEITPKG RALVPDQVKKELLQRIRTFLSAQS-MNIRNSKPEDLMNMQHCNLLCLPENYQMKYYFYHG LSWPQLSYVAEDDKGKIVGYVLAKMEEDPEDSVPHGHITSLAVKRSHRRLGLAQKLMNQA SRAMVETFNAKYVSLHVRKSNRAALHLYANTLGFQINEIEPKYYADGEDAYAMRRDLSEF ----MAHTILLVQPGKKAESRTYSDYESINECLEGVCKIYEEYLKKKCPNQPSITYDISQ LFDFIDNLTDLCCLVYQKQTSTYAPHNKDWIKEKIYVLLRQQAG-MSDEIQEKKDEGTKR IVHTYPLIRHSDMNEEMRTEAMELCVTACEKFTNNNESAAKLIKETMDKKFGASWHCVVG EGFGFELTHEVKNLMYMFFAGTIAICVWKCSMSHRKFSAPRHGSLGFLPKKRSRRHRGKV KAFPKDDKTKPCHLTAFLGYKAGMTHVVRQVDRAGSKVNKKEVVEAVSIVETPPMVIVGL VGYIDTPRGLRTFKTIWAEHLSEECKRRFYKNWYKSKKKCFSKTSKKWSDEMGKQEIEKD LAKMKKYCTVIRVIAHTQMKLMKKRQKKAHIMEVQINGGTIADKVNFAREHLEKHVPIDK VFTVDECIDIIGVTKGKGFKGVTSRWHCKKLPRKTHKGLRKVACI--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------MNAIKCVVVGDGAVGKTCLLMSYATNVFPGEYVATVFDNYSANIMFDGKPINLG LWDTAGQDDYDRLRPLSYPQTDVFLICFSLIKPTSFENVKLKWFPEIAHHCPNTPIMLIG MKLDLREDKETIKKLTEEKRVPITYPQGLA------------------------------ ------------------------------------------------------------ --------------SLPMKKKKIESDRDYTYEELLKRVFDIMREKNPEMMAGEKKTFRMK PPRVQRVGAKKTAFSNFKDICKSLRRSPDHLLSYLFAELGTSGSIDGNDALIIKGKFQEK QIMNVLRGYIIEYVTCHTCKSKETSLQKETRLYFLQCETCGSRCSVQSIKSGFQAVTGKR AAIRAKT----------------------------------------------------- ----------------------------------------------GGFGSVSGKIEIEI KINHEGEVNRARYMPQNPFFIATKTPTSDVLVFDYSKHPSKPDASGECHPELRLKGHQKE GYGLSWNPNLKGHLLSASDDHTICLWDINANQRENRCVDASIVFNGHTSVVEDVSWHLLH DSLFGSVADDQKLMIWDTRCNNTNRPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVA LWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQSAEDA EDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYCDEEPDVAAS ELE--------------------------------------------------------- ------------------------------------------------------------ ----------------------------------HRDVKPHNVMIDHEIRKLRLIDWGLA EFYHPGQEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPFFHGHDNY DQLV-------------------------------------------------------- -------------------------------KVPETLLKKRKQYAENNRVKRKDIFKRAE KYVKEYRTQEREQIRLARDAKRHGNFYVPPQAKLAFVVRIRGINGLHPKPRKILQLFRLR QINNGVFMRLNKATLHMLRIAEPYITWGYPNLKTVRELIYKRGFGKI------------- ------------------------------------------------------------ ------------MEFMLLFSRQGKLRLQKWYVAHPDKQKKKITRELITTILARKPKMSSF LEWKELKIVYKRYASLYFCCAIQSGDNELLTLEVIHRYVELLDKYFGSVCELDIIFNFEK AYFMLDELLLGGEVQETSKKNVLKAIAAQDLLQEETPQG--------MSKAHPPELKKYM DKRLTLKLNGSRVITGILRGFDPFMNLVIDEAIEDKKTGEKNNIGMVVVRGNSIILLEAL ERIEFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTI RLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFQQTTKWIDDVRTERGTDVIIM LVGNKTDLSDKRQVSSEEGERKAKELGVMFIETSAKAGYNVKQLFRRVAAALPGMEQSDS KKMIEVKLNNPPAE---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMVDQT TKSTLGQLPVLKTKAGPRDAELWVNRLKEEYTALIKYVENNKACDNDWFRLQSNKEGTRW FGKCWHIQEHLKYEFDVEFDIPVTYPATAPEIALPELDGKTAKMYRGGKICLTEHFKPLW ARNVPKFGIAHAFALGLGPWLAVEIPDLIEKGLVVHKEILDSFEFLDDVRRMNKRQLYYQ VLNFSMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNYREEPIRAGE IVVFKVEGREIPIVHRVIKVHEKETGQVKFLTKGDNNQVDDRGLYAPGQLWLEKKDVVGR ARGFVPYVGIVTILMNDYPKFKYAILALLGIFVLIHREMTTMNPEYDYLFKLLLIGDSGV GKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYR GAHGIIVVYDVTDQESFSNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEY ADQLGIPFLETSAKNATNVEQAFMTMAAEIKNRMGPTTSQPNPVINPSTPVRPSGG-CCE ESL-EDVLRMSTDEMINRTRLLDSDIKIMKSEIMRINHELQTQKDKIKENAEKIKVNKTL PYLVSNVIELLDVDPEDAAEEEGANVDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEQL KPGDLVGVNKDSYLILDTLPAEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELIEAVVLP MTHRERFETLGIQPPKGVLLYGPPGTGKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGA KLVRDAFALAKEKTPAIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNTN IKVIAATNRVDILDPALLRSGRLDRKIEFPAPTEEARARIMQIHSRKMNVNQDVNFDELA RCTDDFNGAQCKAVCVEAGMIALRR-----------------------------XXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------QIYVDRQLQNRQIYPPINVLPSLSRLMKSAIGEGMTREDHAEVSNQLYACYAIG KDVQAMKAVVGEEALSQEDLLYLEFLTKFEKNFISQGPYENRSIFETLDIGWKLLRIFPK EMLKRIQKKTLEKYYPRD--GPGFVGIRFCQECNNMLYPKEDKENRVLLYACRNCDYQQQ ADNPCIYVNKIEHDVDEITFIIADVIADPTLPRTEDHPCPSCNHREAVFFQSQSKKAEEG MRLYYVCTSPSCTHRWTE------------------------------------------ ------------------------------------------------------------ -----------------------------------------------GVSEETTTGVHNL YKMMTAGTLKVPSINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGRTCVVAGYGDV GKGSAAALRAFGARVIVTEIDPINALQAAMEGYEVATMEEACKYARLFVTTTGCKDIIKG EHMLQMPEDAIICNIGHFDCEIDTAWLNANAASKDTVKPQVDRYTMKNGRH--------- ------------------------------------------------------------ ---------------------------------DQSANTVEEPLDLIRLSLDERIYVKMR NDRELRGRLHAYDQHLNMIMGDVEETVTTVEIDEETYEEIYKSTKRNIPMLFVRGDGVIL VSPPMRT---------------------------------------DITELIASVEGPGG TPYADGNFKLKIIFGKNFPSEPPKAFFLTKIFHPNVASNGEICVNTLKKDWKASLGLKHV LLTIKCLLIVPNAESALNEEAGKLLLEQYNDYCARAKMYTDIHAKPMSQSALSIFQKNGF FNPFGSTSNIKRCIDAAAEGDSCEIGSAKYFALCGLGGVLSCGLTHTGVVPLDLVKCRLQ TNSAKYVNLFTGFKVTIAEEGLKGLARGWAPTFFGYSVQGLGKFGFYEVFKSIYGGFLGE ENAYLWRTSMYLAASASAEFFADIGLCPFEAVKVKIQTQPGWADTFKEGFPKLYQEEGLF GYYKGIVPLWGRQIPYTMMKFACFEKTVEFLYKNVVPKPRAECSKGEQLIVTFVAGYIAG VFCAIVSHPADTLVSKLNQEKGTSIVSLSKRLGWAGLWKGLGPRIVMIGTLTALQWFIYD TVKVVFRLPRPPPPEMPASLKAKLE---------------VPPALIYIFDTMLLTIVMHC HWGLEGVVLDYIHLSSCAFAGLCHLNYLDVGFGKLVQNLFTQL-EAPEEDASELIFSKEF DNATTLLISEVKRKQQNESAEEEQELSDVFTKTLAYTERFSKFKNRETIAAVRNLLQTMK LHTFEIASIANLCPENAEEAKALIPSLEGRFDDEDLQNMLDDIKTKLSFQY--------- ------------------------------------------------------------ ---------IYKCDDPKVGRPQCYTSRGSSYPDEFPCEFSNQGKFKIIRHVSFVDCPGHD ILMATMLNGAAIMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHIIILQNKIDLVKESQ ASEQYQQIERFVKETIAEGAPIIPISAQLKYNIDAVCEYIVKKIPIPVRDFTREPRLIVI RSFDVNKPGCEVDDLKGGVAGGSILRGILKVGQEIEVRPGIVTKDATGKIACQTIYSKIV SLFTEQNDLLYAVPGGLIGVGTKIDPTLCRADRMVGQVLGAVGTLPDIYTEIEISYFLLY RLLGVRTEGNRKGAKVTKLAKNEVLMVNIGSLSSGGRVIGAKGDGAKIALTNPVCTEVEE RIALSRRVEKHWRLIGWGTIKHGVKISQMAELLLDSNIRFWVFLPIVVVTFLIGVIRHYA TILLSSEKKVEASQIADSQALIRSRMLRENGKYIPKQSFLMRKEFFNNDVNGFFVRNPMT DPTMMTDMMKGNMTNVLPMIVVGGWINWAFSGFLTTKVPFPLTLRFKPMLQRGIELSSLD ASWVSSASWYFLNVFGLRSMYNLVLGQDNAADQTKIMQDQMSGAAMAMPPDPSKAFKAEW EALQIIDHQWSLEGVEDELCMFLFDWLAGVLNYLGLYKKSGKLVFLGLDNAGKTTLLHML KDDRMAQHVPTLHPTSEELSMGNMKFTTYDLGGHQQARRVWKDYFPAVDGIVFLVDTFDK ERFEEAKAELDSLLSDEQIASAPVLILGNKIDKPGAASEEEIRFWFGLNGHTTGRGQVSR NELRPIELFMCSVLKRQGYGEGFRWIAQYINILRRNRPGIKMDNWSNWPDKSFDEMDSTL AVQQFIQQAIRTNFANIEGILTPPDGQDEGVWKYEHLRQFCMELNGLAIKLQQECNPETC TQMTATEQWIFLCAAHKTPKECPAIDYTRHTLDGAACLLNSNKYFPSRVSIKDASVAKLG SVCRRVYRIFSHAYFHHRPLFDEFENETALCQRFTLFVTKYNLMSKDNLIVPILDDQMAV IKLQSSDGEEFEIDVQIATQSGTIKTLLEDDDGEEDPIPLPNVTAAILKKVIYWCTHHKD DPPPPEDDENKEKRTDDITSWDAEFLKGDQGTLFELILAANYLDIKGLLDVTCKTVANMI KGKTAEEIRKTFNIKNDFTPQEEEQVRKENEWCEDKNKRLTKGGKKGGKKKIVDPFSKKD WYDVKAPSMFTVRTIGKTVVTRSQGTKSASDGLKGRVFEVALADLVQDEIAFRKFKLIAE EVQGRNVLTNFHGMNLTTDKLRMMVKKWQTLIEANVDVRTTDGFLLRMFCIGFTKKSTNQ VKKTCYAQHTKVRAIRKKTSD--------------------------------------- ---------------------------------TGEVITRPEGYEPPVQESV-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --TISFIPPDGEFELMSYRLNTHVKPLIWVESVIERHAHSRVEYMVKAKSQFKRRSTANN VEILIPVPHDADSPKFKTTTGSCKYAPEQDAVIWNIKSFPGGKEYLMRAHFGLPSVLGEL SEGRPPIHVRFEIPYFTVSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRTQ------ ----------------------LLKARLAKLKRELIEPKGGGGGATEGFDVAKTGDARIG FVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDG KGRGKQVIAVARTCSLIYIVLDVLKPLQHKKLIEYELEGFGIRLNKQPPQIGFRRKEKGG INLTATVTQNELDLDTVKAILGEYKIHNADIVLRYDATSEDLIDVVEGNRVYIPVIYVLN KIDQISIEELDIIYKIPHCVPISAHHKWNFDDLLEKMWDYLSLTRIYTKPKGQLPDYNAP VVLKNGLNTVEDFCNKVHRSIIKEFKNALVWGSSVKHQPQKVGKEHLLHDEDVVQIIKKM AKHHPDLIFCRKQAGVAIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGSYQGRCVIC GGPGVSDAYYCKECTIMEKDRDGCPKIVNLGSAKTDLFYERKKYGFKKRPNLPPISSEKL MSQSGLRKIPVPVHRYAPLKEHWMKIYSPIVEHLGLQIRFNLKSRNVELKASKDTTDIGA LQKGADFVRAFTCGFDVDDAVALLRLDDLYLDSFEVTDVKPLKGDHLARAIGRIAGKGGK TKFTIENTTKCRIVLADQKIHILGAFNNIKVARTAICNLILGSPPSKVYGNMRAV----- --RIKVDKPVVELDGDEMTRIIWTMIKDKLIFPYLDVECLYYDLGLPYRDATDDQVTIDC AEAIKKHNVGIKCATITPDEERVEEFNLKKMWLSPNGTIRNILGGTVFREPILCQNIPKL VPGWTSPITIGRHAFGDQYRAKDMVVKGKGKFEILLTQEDGSEERIEVFNFDN-GGVLMG MYNTDESITGFAHSCMQYALKKKWPLYMSTKNTILKRYDGRFKDIFEDIFQQNYKKQFDD LGVWYEHRLIDDMVAQALKSSGSFVWACKNYDGDVQSDIVAQGYGSLGLMTSVLMCPDGK TIEAEAAHGTVTRHYREHQKGNRTSTNPVASIFAWTRGLEHRGTLDGNKDLIRFCNVLEQ TCVQTIEEGKMTKDLAGCIYGLRNVKPEHYLFTEDFLEAIQE------------------ ---------------------------PTSGFCIKAVHLKNAILNIKELGGGKNVKPYWK HYFKGAEAMIFVVDSASSEKLKEAAETLHMLSTDETLRSLPILLIANCQDKPYAQ----- ------------------------------------------------------------ ------------------------------------------------------------ -DDDNLSDDEDLFGTEKEKLHKERVAAYQTKKAAVVIAKSNVILDVKPWDDETNMTEVTS LVKEIKIDGLLWGASKLVPLAYGIKKLQISCVVEDDKVSIDDLQEKICAFEDHVQSVDIA AFNKV------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------YDLGQKMIECLT KEKVQAGDIVTIDKATGKISKLGRSFTRARDYDAMGTQTRFLQCPEGELQKRKEVVHTVS LHEVDVINSRTQGFLALFSGDTGEIKSEVRDQINLKVAEWREEGKAEIVPGVLFIDEVHM LDEESFSFINRALESDMAPILVVATNRGITKVRGTQYESPHGIPTDLLDRLLIISTNPYE EKEIKQILKIRCEEEDVEMSDDALTVLTRLGMESSLRYSIQLITTANLVCRKRKATEVGV EDIKRVYSLFNDVSRSTQFLEEYQQDFLFHE---FDLTTRLAPYLDRHLILPLFEFLCGL QVYDAKDIQKAKLQILKTTKMVDFLIDEHKDLYGGGDAPTEFMQRRKETINELDYYNNLV KPIDHCLQQDEVLMQEIRDGRQLYDVLVKDFSFQENWIEILFKYAKLQFEVGNYDSANAN LHIVQVLINPNDKLYLPAVWGRLACLILMQDWETALEEVERLKENIETPLQALQQRTWII HWGLFLFFNHGKGKDIMIDMFLYQPLYLNAIQTLCPHILRYLAAAAIINKNVLKDLVKII QQESYTYKDPVTEFLECLYVRFDFDGAQQKLRECETVLKYDFFLVACVDDFIESARLFMF ETFCRIHQCISINMLASKLNMMPEEAERWIVNLIRTSNLEARIDSRLGHVVMGQQAVSLY QQVFDKTKNLSIRTQMLVMKIENKKELKKMGVTVDHIVQGTGAK-PESGQKIQAHYVGTL QDGSEFDSSRKRGKPFEFTIGIGQVIKGWDEGMMQIAVGGRAKLTVSPDYGYGARGAGGV IPPNATLFFDVEILKI---KYYCDYCDTYLTHDSPSVRKTHCNGRKHKENVRIFYQKWLE EQVQKLVDDTTAAFKAGVGDKK----GGAAIPPPGQA-PGPMGPAMPMMGPGPMGPGGPM RPGMAPMGPMPPGMPGP----------------------------------LQSEFFNSV REVYENVYETVDISGSPEVRANATAKATVAAFAASEGHAHPRVVELPKTEEGLGFNVMGG KEQNSPIYISRIIPQGVADRQGGLKRGDQLLSVNGVSVEGEPHEKAVELLKAAQGKVKLV VRYTPRVLEEMEARFDKQRTARRRQ-------------IHFDEKFWENRWIDSKHKGSDQ GKFVLSAGKFYNDAAVDAGLKTSEDARFYGISAKFDSSINTEGTPLVVQLTVKHEQNIDC GGGYVKIFPSSLDQTDMHGDSPYGIMFGPDICGPGTKKVHVIFNYKGENLLTKKDIRCKD DVFTHIYTLIVRPDNTYEVKIDNKKVESGSLEDDWDFLKPKTIKDPEAKKPEDWDDNEKI DDPADTKPEDWDKTEHIPDPDAKKPDDWDDEMDGEWEPPMIDNPEFKGEWKPKKIDNPNY SGVWKHPEIDNPDYVADDKLYLQKDLSYVGIDVWQVKSGTIFDNVLLTDDEEVASKAAE- --------------------------------------------XXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNVFRLIGDLSHLLGIILLLLKV WKTRSCAGLSGKSQIMFAMVFLCRYLDLITNFVSLYNTAMKTFFISSSLLTVYLMYFKFR ATYDANHDTFRMEFLIVPVAGLAFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGE AESITSHYLFALGSYRALYILNWCYRYYFEGFFDLIAIVAGCVQTVLYCDFFYLYITK-- ------------------------------------------------------------ --------------------------------------------------YSSEIKKTEV LMENFRRSIGLRIKETKEVYEGEVTELSPVETESPMGGYGKTVSHVIIGLKTAKGTKQLK LDPSIYESLQKEKVEAGDVIYIEANSGAVKRQGRSDTYATEFDLEAEEYVPLPKGDVHKK KEIIQDVTLHDLDCANSRPQGGQDIMSMMGQLMKPKKTEITDKLRKEINKVVNKYIDQGI AELVPGVLFIDEVHMLDIECFTYLHRALESTIAPIVIFATNRGRCRIRGTDDNLSPHGIP LDMLDRLMIIKTLPYPQEEILQIISIRAQIEGVSINDDALKKLAEIGVKTTLRYATQLLT PANVLAQVNGKESIEIDDVDEVNELFFDAKTSAKILQEQSDKYMKEFEVDEEGDQGLLKL KDKVKKRKGRGF-TRGGVKQYEGMEVAGPGPQRSVEGWILFIANVHEEASEDDIMDKFAD YGDIKNLHLNLDRRTGFIKGYALVEYETFSEAEAALLNLNGEEILGQKISVDWCFVR--- ----NYQLYRNTTLGHTLQESLDELIQSGQINPQLALKVLLQFDKAINAALSSRVKNRMT FKGHLKTYRFCDNVWTFVLNDVEFRSANKVKIVACDGKSTFLFTSESVGEGHPDKICDQV SDQVLDAHLRQDPNAKVACETATKTGMVMLLGEITSKANVDYQKIVRDAIKYIGYDDSNK GFDYKTCNVICALEQQSPDIAQGVHEGRNEEEIGAGDQGIMFGYATDETESCMPLTIMLA HKLNQRIAELRRNGLMPWARPDTKTQVTCEYKIENGATIPIRVHTVVVSLQHSDDITLEE LRSAVMEKVVKAVIPEKYRDEKTIYHIQPSGRFVIGGPQGDAGVTGRKIIVDTYGXWGAH GGGAFSGKDFSKVDRSAAYAARWVAKSLVMAGLCRRVLVQLSYAIGVAEPLSIYVDTYGT GTKSESEILEIVKNNFDLRPGVIVRDLDLRRPTYRRTAAYGHFGRPEFTWEQPKKLVFMA GSALRRLMAEYKQLTLNPPEGIVAGPINEENFFEWEALITGPEDTPFECGVFAARLTFPP DYPLGPPKMKFACDIFHPNIYPDGRVCISILHAPGDDPMGYESSAERWSPVQSVEKILLS VVSMLAEPNDESAANVDAAKTFRENRAIFDEIARKTVKKSLGFMRLEKCYFCSSTVYPGH GVQFVRNDCKSFKFCRSKCHKAFKMKRNPRKVRWTKAFRKSAGKELTVDQSLEFEKRRHV PVKYTRALWSKTVVAMKKIENIKSKRQAQFVNQRLKKGKQLRKQLDIQEVEKNIHMIRAP GAK---YKLVMVRHGESEWNKENRFTGWYDSDLAESGVHEAMSAGQMIKEASLNFDIAYT SVLKRAIKTLYYIQDGTDMHWIPVERTWRLNERMYGALQGLNKSETAAKHGEQQVKIWRR SYDTPPPPVDESDPRFPGNDSRYARINRSLLPKSECLKDTVARTLPFWNETIAPAIKKGE KVLVVAHGNSLRGIVQYLDNMSEDAIMGLNIPTGVPLVYELDQNLKPIRHYYLASDEQVK AAMDKVAAQGKSKMEQEDILYNKGEYIETASGNKVSRLSILCGSQNIVLNGKTIISNECI IRGDLANVRVGRHCVISPRAVIRPPFKKFSKGVAFFPLHIGDHVFIGEDSIINAAQVGNY VHIGKNCVIGRRCCLKDCCAIADNTVLPPETVVPPFTVFSGSPG---------------- -------HQYELMQYAAVTLGSGDLRQAVVLPDGEDLNEWVAVNTVDFFNQINMLYGTMT EFCTIHSCPIMSAGPKYEYHWADGHNIKKPIKCSAPKYIDFLMTWVQNQLHDEALFPSKI GVPFPKNFMSIAKTILKRLFRVYAHIYHQHFDQVVQLKEEAHLNTSFKHFIYFVQEFDLV SRNELAPLQAVMDKLISK-MGIDITHKHDRKVRRTEPKSDDVYTRLLVKLYRFLARRTDA KFNKIVLKRLFMSKTNRPPLSLARLVRNMKK----------------------------- --------------------------------DNEPLLQGPRKARKAYRHFGRAPGVPHS NTK--------------------------------------------------------- --------------------------------------IIDAINEVIQETETTRSALEHI HSNEVIRTVEAFLKKKFSVIVAECQGHKLAASLADNGIETTIITDAAIYAMMSCVNKIII GTNCVLANGGLKAPGSYTLALAAKQFSVPVLICAARYKISPQYHYSSNANFNKCASPLDI LNPLYDYVPPELVTLIISDQGGYAPSYVYRLLSDLYHMIIPVRCFTCGKVVGNKWEAYLV LLQAEYTEGDALDALGLKRYCCRRMILAHVDIIEKLLNYAPLEKXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-AKDKMKAYWDKNLNRPNSPWIQYKWQV NMMSSLTNRVTGVAMTAGLYIAAYGLLFLPYSTEFYMTSLKALELGPLFWFPVKTIVAYP FVYHTLNGVRHLAHENKLGYEIKGQLNTGYACLAGVAY-GGSIEISSYRDQHFKGSRGEQ ERLLKGSCTLYIGNMSFYTTEEQAYELFGKAGDIKRIIMGLDKYKKTPCGFCFVEYYVRD DAESAVRYLNGVRLDDRIIRTDWDAGFKEGRQFGRGKSGGQVRDEYRTDYDSGRGGYGKI IADK-------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------------------LID DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGQKNEKYCIFANFSVTGG KWIVSGSEDNLVFIWNLQTKEVVQKLAGHTDVVLCCACHPTEHIIASAALENDKTIKLWK SDVMIVYSDVFAGCEVVTDSYTGVMYKVAAKDDSVFGGNQSSGVNVALSNSKQFQDYVKS YMKTLLNLTFYTGIIPCYWENCSLFFWQKGL-----IALEYGEGVVIAADSRTTTGTYVA GRVSDKLTKVSDKIYVCRSGVSADTQAVANVAAYHLNLHRMEMGQDPLVRTAAAIFQDLC YTNRDNLTAGMICAGYDDKIGGQVYTVPLGGMLVRQPISIGGSGSAYLYGFVDATYKKNM SKDECLRFVKKAVSLAIERDGSSGGNCVFAVINKDGVEKGIVMNPDLPK----------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------YYNESFTFEVPFEQIQKISAHVTVVDYDRIGT SEPIGRVALGCNATGSALRHWSDMLANPRRPIAQWHTLEEVPEKS--------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------SPDNIIFVMDA SIGQACEGQAQAFKDKVDVASVIITKLDSHAKGGGALSAVTKSPVIFIGTGEHIDDFEPF KVQPFVSKLLGMGDIEGLIDKVNELKLEDEELMKKLKH---------------GQFTLRD MYEQFQNIMMSIFTYNGGSVVAMTGKKCVAIATDKRFGIQFQTIGMENEKCFQMGKHLFL GLTGLATDITTVNERLKFRINRYLLQENRELKPKTFLNIVSNLLYEHRFGPYFVGPVVAG LDPKTFEPFVASTDLIGCASESEDFVVSGTGEEQLYGMCESVWEPDMEPDQLFECISQSI LNAVDRDAISGWGISVYIIEQDKITKKTLKARMDMTSKDYYFDSYAHFGIHEEMLKDEVR TLTYRNSVLHNKHLFKGKVVLDVGCGTGILSMFCAKAGASKVIGIECSSISEYAEKIVNC NNMGDVVKIVKGKVEEVELPDGIDKVDIIISEWMGYCLFYESMLNTVIYARDKWLKPGGL IFPDRATLYVTAIEDRQYKDEKINWWDSVYGFDMTPIRKVAISEPLVDVVDPKQVITNAC LVKEVDIYTVKIADLAFRSPFHLQCRRDDYVQALVCYFNIEFTKCHKRTGFSTAPEARYT HWKQTEDYITVKQGEEIYGVVALSPNEKNVRDLDFSIDIDFRGELSEMVESNNYKMRMVK EDKTTWKSNYFIKLVNLMTEFPKCFIVQADNVGSKQMQQIRIALRLLMGKNTMMRKAIRG HLESNPMLEKLLPHIKGNIGFVFTKDDLIDIRDLILANKVAAPAKAGALSTNVVVVPAIN TGLGPEKTSFFQALAIPTKISKGTIEILNDVKLLSPGDKVGASEATLLNMLNISPFTYGL KIEQVYESGTVFAPSVLDITDEDLRS---------------------------------- -----------------------KGKLFAVIGDEDTCTGFLLGGIGELNRKREANFFVVD KNTSVSAIEEIFKSFLSRGDISIIFINQNIAEMIRHLLDAHVAPVPAILEIPSKNCPYDS SKDSILRRAKGLFSADDFR----------------------------------------- ------------------------------------------------------------ ----------------MVGNNLKDAQLQQIVDKTIIHADTDGDGKISFEEFCLVVGSMDV HKKMVVDVMTFIDNWEEFAKAAEMLYTSDPTKCRFVTKYRHCDGKLTIKLTNDAVCLKYD TEHAQDVKKLEKLTSQLMRHMASRD----------------------------------- ------INKNKYTSACSKLLVQYKSAFKQVEGGEFPTIDVFINKYKLDCPAAHERIKDDR PITIKDDKG-TYQLINDITAMYISIMDKLKLEIRAMDEIHPDLKDLMENIKRCSLVPSDF EGKEKIRKWIQTFEAMQACDELTDAQSRQMSFDIESSYNDFTYVLN-MLSQMLKEHQIRQ HVQREIQEKKKKEAIVATNLAHAVVDHLNTGVAQAYVNQKKLDTETKILQANATQFVKQT SLWLKLVEDFSNSLKEIGDVENWAKSIENDMRTISSALEYAYKQRIVEKQMKGDKNGEKR LVRSSRMTKYYPTEDKPRKRFSCFKDH--KLRSTITPGTVLILLAGLHKGKRVVCLKQ-- ------------------------------------------------------------ ------------------------------------EKKLLTGYLGSMFSLKNHQYPHKM I-MEFLFGKKVTPQEMLRKNQRALNKAMRDLDRERAKMEQQEKKTIADIKKMAKQGEMAA VKVMAKDIVRTRRYVKKFIMMKASIQAVSLKIQTLKANDSMATAMKDVTKAMGRMNKQMN LPQIQKIMMEFEKQSEIMDMKEEMMSDAIDDAMGDEEDEEEGDAIVQQVLDELGLQMTDQ LSDIPGIKDTKGKQPV--MDEDADLMARLENLKK---------------KKTGTREELVS CSDCGRSGHPSCLQFNANMIISVKKYPWQCIECKSCGICGTSDNDDQLLFCDDCDRSYHM YCLKPPLAEAPEGSWSCHLCIMEFY----------------------------------- -----------------------------------------PGGELAPNEDQVEGLKRLL NETLVRNDGPQMDWQVEDIIGNWWRPNFEPPQYPYIPAHITKPKEHRRLFVVQLPEKALF AVPRNYKLVAAPLFELYDNSGGYGPIISSLPQALSRFNFAY------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------KMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGAEFVS AREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVC TTVAIAIVAETCSPFTVLPALMNEYRVPELNVQNGVLKSLSFMFEYIGEMGKDYIYAVAP LLEDALMDRDLVHRQTAMAAIQHMALGVFGFGCEDALVHLLNYIWPNVFETSPHVVQAFM GAIDGLRVGMGAPKVLQYSLQGLFHPARKVRDVYWKVYNTVYIGSQDSLIPAYPRIPNDE KNTYIRYELDYLL----------------------------------------------- ------------------------------------------------------------ ----------------------------EAKNDRLWFKTNTKLGKLYFDNRSFNKLSKIL KQLHASCQTEDGEDDLKKGTQLLEIYALEIQMHTEQKNNKKLKALYEQSLHIKSAIPHPL IMGVIRECGGKMHLREGEYDKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGIN PFDSQEAKPYKNDPEILAMTNLVNAYQNNEINEFNEIIAQSEETIMNDPFIREHIEDLLK NIRTQVLIKLIKPYTRIRLDFISKELKISVPDVISLLVSNILDNVIHGRIDQVKQVLELT SGDARFEALDKWSSQLMSLHQSLTNIM--------------------------------A TIDVEHSHVRFLGNLVLNLWDCGGQESFMENYFHSQRENIFKNVEVLIYVFDVESQDLNR DSHYYMSCVEAIMNNSPNAKIFCLVHKMDLVQEDQRERIFNERQKDLLKVSLPVATSIWD ETLYRAWSSIVYQLIPNVQALELNLKSFADAIDADEVLLFERATFLVISHCQQHPHRDIH RFEKISNIIKQFKLSCSKLAASFQSMEVRNSSFAAFIDVFTSNTYVMVISCDPSIPSAAT LINIKNARKHFEKLERVE------------------------------------------ ------------------------------------------------------------ -----------DPGAGLVAAAMIAIVPGYISRSVAGSYDNEGIAIFCMLFTYLLWIKAVK TGSVFWSVMCALAYFYMVSSWGGYVFLINLIPIHVFILMLIGRFSHRVYIAYCTVYCVGT ILSMQISFVGFQPVQSSEHMAAFGIFGLCQIVAFIDYLRSRLNTEQFEVLFRSLVIAASS VVTMASGKVAPWTGRFYSLLDPSYAKNNIPIIASVSEHQPTAWSSFYFDLQILVFLFPAG LYYCFKNLSDANVFIIVYGVTSIYFAGVMVRLMLVLAPVMCILSGIAISSTLTAYMKNLD VTKKGDSSYPLKNEVASGVIVMICFFLVSYTFHCNWVTSEAYSSPSIVLSAHSGDRGRII FDDFREAYYWLRQNTPEDAKVMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMAS TEEKSYEIMRELDVNYVLVLFGGIAGYSSDDINKFLWMVRIGGSTELGQHIKETDYYTPK GEFRIDKEGSETLLNCLMYKMSYYRFGEVYTEQGKPSGYDRVRNAEIGNKDFELDILEEA YTTEHWLVRIYKVKDLENRGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------KRLGEFFQNKYDWDLLAARSIWAFGPDSTGPNILVD DTLPSEVDKALLTSVKESIVQGFQWGTREGPLCDEPIRNVKFKILDAAIAQEPIHRGGGQ VIPTARRVAYSAFLLATPRLMEPYCFVEVQAPADCVSAVYTVLAKRRGHVTQDAPIPGSP LYAIKAFLPAIDSMGFETDLRTHTQGQAFCLSVFHHWQIVPGDPLDKSIVIRPLEPQPAT HLAREFMIKTRRRKGLSEDVSINKFFDDPMLLELAKQDVMFSYSMQETFNLFDNKGDGKI FAQQLGEVLRSLSLNPTEAEVKKCNQPDYRVSFEMFLPIYQTLSKNRDTTSGEEFYEGFR VFDKDQNGTISGAEFRHLLTSLGEKLTMDEVEQLLVGMEDSQGNVNYEELVRQIMS---- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------FHSFCKELGDPTSEVMCDILAFEADRRAFIITINSFGTELSKDDRVKLYPRCGK LHPDGLALLARADDYEQVRSVAESYTEYKMMFQESGNNPGEKTLEDKFFEHEVSLNKNAF MQQYHFGVFYAYVKLKEQEVRNIIWIAECVAQRHRAKIESYIPIF--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------VSWSKHSNELVST HGYSQNQILVWKYPSLIQIAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTR STKESKSVLNMFTSIRVLFLIALLYLISGFGWKISVGWFLSETSPYMWGNLGIAFAISLS VVGAAWGIQTTGASIIGGGVKAPRIKTKNLVSIIFCEAVAIYGIIMAIVISNSKNQEAGF RMFGAGLTVGFCNLFCGICVGIVGSGAALADAQDASLFVKILVIEIFASAIGLFGVIVGI LQVSGASMGNSMASTRRLRKELHDQVDESNILVWSVLILPQQDPFRKGGFKIEIVYPPEY PFKPPKITFKTKIYHPNIDEKGQVCLPIVSPENWKPATKTDQVLQALVSLIHDPEPEHPL RGDLAEEYSKDRKKFNKSAEEHTKKHAEKR---GAALFYPSQCSALRKNNHCLIKGRPCK IVDMSTSKTGKHGHAKVHLVALDIFTGKKLEDICPSTHNMDVPIVTRTEFQVIDYDEKIF TLMDDNGIIREDLTYNASVVCSMEEEHVKDLK---------------------------- --------------------------HFCAVNNDNNIIITDFHNHCVKIFDEGQFLFSFG SNGEGNGQFNAPTGVAVDNSGNMLVADWGNSRIQVFD----------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------DIFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDAADASIESM NGQYLCNRAISISYAFKKDAKGERHGTPAERLLAAQNPLAQADRPHQLFADAPSMMPGMP SVMPPPPPMGGFPPGMPPPMQP--FPRPPIPP---MPMPPMMPPPPQPSGMPMPVSMSQP RPPPMPRAPPPPIGNPPLPPKSESKKKVNPLFEKRPKNFGIGQDIQPKRDLSRFVRWPKY IRLQRQKAILMQRIKVPPPIHQFSQALDKQTATHLFKLLEKLKPEPRKEKQARLKARAEE RVAGKPDVPTKRENVVRTGINTVTTLVEKKKAQLVIIAHDVEPIEIVLFLPALCRKMNVP YCIVLGRVVGRKTLTSMAITHVNPEDRGSLD----------------------------- -------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--IEFVKAR QIFDSRGNPTVEVDLKTDKGLFRAAVPSGASTGIYEALEMRDKK-DEYHGKGVKNAVANV NNIIAPHMNINLADQIGIDNFLLKLDGTQNKSQLGANAILGISLAVCKAGAAQKEVPLYR HIADVAGKKNIILPVPAFNVINGGSHAGNRLAIQEFMLLPTGAATFKEAMRMGSEVYHHL KAGIKKRYGQDACNVGDEGGFAPSIQNNFEALDLCVEAIEKAGYTGRIQIGMDVAASEFC KKYDLDFKNSKSEPGHWLDSDQLQSVYTDMVSKYPLISIEDPFDQDDWDAWTKMTSIQIV GDDLLVTNPTRVADGIKRKACNCLLLKVNQIGTVTEAIKACLMAQAQGWGVMVSHRSGET EDSFIADLVVGLSTGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKFAGIHFRFP----- -------------------------------------WKAAIEKLDFHHYLPLFCNGLKE TEHPYAFFAEQGFHDMLEHGHNKVLPVVPQLIIPLKEALNTKIKSVVCVTLKAIQHLVIC QDVVGEALVPYYRQILPILQLLKGKNLNSGDGIDYSQQKRDNIGDLINETLELLEKHGGE DAFINIKYIVPTHES--MNAPPSFESFLLFAGEKKIVIQKDSKVKCAAIFTINKEDHTLA HALNTQLHKDPKVMFSGYKVPHPLEYKVQIRIQTTSDYSPQEALTNAITDLISEFSLLEE QFKEAIRDKQIGDEDHRKKWDLEEYERIAFERLQAQVERKDPPVRRELLKPREYRVDLDS KLGKSQVITKTTPSSLQGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLD QVKKRFEQNKKKVEEKKKEYDFEERMKELREEEEKNRAYKKEKRKDRKRKGTDDDVNPAM ASMMGFAGFG-------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ EEAAAYIQAQFEAKNKSTTKEIYCHQTCATDTKNVQFVFDAVTDVIIANNLRGCGLY--- ------------------------------------------------------------ --TECLRKLQKASSKLNGTKELMTLAISNFSIPGDSQFPLNVMYGRPQDSNEADLIRQYF TQLRQEIGIRLIEKVFDPQTDKPSKWWMCFVKRKFM------------------------ ---------------------------------------------------GQERFRAVT RSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIFLIGNKSDLDAQRDVTFE EAKQFADENGLMFLECSAKTGANVEEAFLDTAKKIYQNIQDGSLDLNAAESGVQHKPNPT RNPLNPDPNPPKDICTC-----------GSVGGVLSFTQDGEVKVSGKVTGLAPGNHGFH IHEFGDFSNGCISAGPHFNPDNKVHGAPGDEIRHAGDLGNISANNVDLEDKLVRLTGPKS VIGRAVVVHEGVDDLGKGGH----------------------MVNFTVDEIREIMDRKKN IRNMSVIAHVDHGKSTLTDSLVSKAGIIAGSRAGETRFTDTRKDEQERCITIKSTAISLY YQMNEEDCGNDFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQA IAERIKPILFMNKMDLALLTLKLSSEDLYQTFQRIIETVNVIVATYYDEGGPMGDIQVNP GKGTVGFGSGLHGWAFTLKQFCDMYKEKFKISEEKLMKRLWGDTFFNVTRGFCFFIMEPI CKIFDVCMHHDEALVAIDKVGVKLTTEEKDLEGKHLLKTVMRKWLPAGEALLQMISIHLP SPHTAQKYRMELLYEGPMDDACAVAVKNCDPDGPLMMYISKMVPNADKGRFFAFGRVFSG RVGTGQKVKIMGANYVPWKSIQRTILMMGRYIEPIEDVPCGNICGLVGVDQYMVKTGTIS TLEEAHNMKVMKFSVSPVVRVAVEVKNPSDLPKLVEGLKRLAKSDPMVQCSIEESGEHII AGAGELHLEICLKDLEEDHAGVPLKKSDPVVSFRESVSEESSIVCLSKSPNKHNRLFMKA APLPEGVSEDIDSGKITTRQDFKERARYMADTYEMEVGECRKIWSFGPEGTGPNLVIDVT KGVQYLNEIKDSVVAGFQWASKEGVLAEENLRAVRFNIHDVTLHTDAIHRGGGQIIGTAR RCLLACQLTASPRLMEPVYLVEITCPMSVVGGIYSVLNRRRGMIIEENRVAGTSQTVCKA YLPVVESFGFTADLRSNTGGQAFPQCVFDHWNLM-------------------------M LPLSLLRTAVNHPMLVELKNGETYNGHLVSCDSWMNINLREVICTSRDGDRFWRMPECYI RGSTIKYLRIPDEVIDMVKEDVMLRGRGRGDGR-RGRGVSGRGSFGGRGGRGPGGGRGGA QKN--------------------------------------------------------- ------------------------------IGMHDEAIRCIEYTPELNLVVTGSWDSTVK LWDSRSYHCTGTYSQPDKVYTLSLCGDKLVVGTAGRRVLVWDLRNMAYVQQRRESSLKYQ TRCIRCFPNRQGYVLSSIEGRVAVEYLDPNPEIQKRKYAFKCHRIKEEGLEKIYPVNAIA FHPSHNTFATGGSDGYVNVWDGFNKKRLCQFHRYPTSISSLAFSLDGSVLAIASSYMYEM GPPEDAIYIRKVTDQETKPKMDFQNRVGGKTGVGGVASASESNRDRRERLRQLALETIDI NKDPYFMRNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQANLARRAAKEAKDAPANPAPE RRAVDIKKFVKIGRPGYKVTKQRDPETTQQSLLFQIDLPEIVEGIVPRHRFMAAYEQKVE PPDKKWQYLLFAAEPYETIAFKVPSREVDKEGKKFWTHWNKETKQFFLQFAFKIDLSSAP RPPPPMKPPLVNMDDEQETNKLWRIRKTIMQLCHDRGYLVTQDELDQTQEGFKLQFGDKP SERRPSRGDLIILVAHNDDPTDQMFVFFPEDAKIGVKIVKFYVQKMQEENIFRAIIIVQH GMTPSAKQALDDMAPKYTLEKFHESELLVNITEHSLVPVHIVLKSEEKQELLIRYKLKEF QLPRIQVHDPVARYFGLKRGQVVKIVRPSETAGRYVSYRLCVDTKESIGTVIGIDLGTTY SCVGVFKNGRVEIIANDQGNRITPSYVAFTAEAERLIGDAAKNQLTSNPENTIFDAKRLI GRNWNDAAVQKDIKFFPFKTIKLNDKPHVQVQVGAETKTFAPEEISAMVLNKMKETAEAY LGKKVTHSVVTVPAYFNDAQRQATKDAGTISGMNVMRIINEPTAAAIAYGLDKKEGEKNI LVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLFKKKFGKDIRK NNRAVQKLRREVEKAKRTLSSQHQAKIEIESFFEGEDFSEVLTRAKFEELNMDLFRSTMK PVQKVLEDSDLKKNEIDEIVLVGGSTRIPKVQQLVKELFNGKEPSRGINPDEAVAYGAAV QGGVLSGEEDTGDLVLIDVNPLTLGIETVGGVMTKLIPRNSVIPTKKSQIFSTASDNQPT VTIQVFEGERPMTKDNHQLGKFDLTNIPPAPRGVPQIEVTFEIDVNGILKVSAEDKGTGN LEKIVINNDQNRLTPEDIERMINDAEKFADEDKKVKEKVESRNELESYAYSLKNQIGDKE KLGGKLSDEDKTAVEEAVNEAIEYLEANQEAEAEEYKTQKTKLEGIVQPIMSKLYNTAPP PTESEEHDELDDDVNDPDIEAIQARVREMEEEAEKLKEMHNEVEKQMSHEEKLEADGRSI YVGNVDYSATAEELEAHFHGCGSVNRVTILCDKFTGHPKGFAYIEFADKDAVQTAEALDD SLFKGRQIKVSVKRTNRPGISTTNRPPRRFPQRPRARHFNPYHGGRPRGRG-FRPRRGSW YSPY-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------LKASRA KDAVRMKELSKLFTEYEKVVVEDRIEKEKARRKAEHEQMELNSAIMVQSWWRGVMVRNSI GVFKRKKKGKAKVGINGFGRIGRLVLRASMDDVQVVAVNDPFIDLDYMVYMFKYDSTHGR FKGTVELVINGNSITVHGERDPANIPWGSDGAEYVVESTGVFTTIDKASAHLKGGAKKVV ISAPSADAPMFVMGVNHEQYDPSMQIVSNASCTTNCLAPVAKVIHDKFGIKEGLMTTIHA YTATQKTVDGPSGKAWRDGRTAAQNIIPASTGAAKAVGKVIPALNGKLTGMAFRVPTPDV SVVDLTCNLEKQASMDEIHAAVKGPMKGVLEFTDELVVSSDFIGDRNSSIYDSKACMQLT PTFVKLVSWYDNEYGYSCRVVDLLKH---------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------GRLEVLRIHTKNMKLADDVDLE QVANETHGHVGADLAALCSEAALQQIREKMELIDLEDDTIDAEVLDSLAVTHEDFRWALG KSNPSALRETAVEVPNVTWDDIGGLESVKRELQELVQYPVEHPDKYLKFGMTPSKGVLFY GPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVRDIFDKARAAAPCVLFFD ELDSIAKSRGGSGGDGGGAADRVINQLLTEMDGMSGKKNVFIIGATNRPDIIDSAILRPG RLDQLIYIPLPDELSRQSILKSNLRKSPISKDVDLNYLAHVTNGFSGADLTDICQRAVKM AIRENIEKEITREKERASNPDDYDPVPEIRRDHFEESMKYARKSVNEADTRKYQMFAQTL QQSRGLGQ---------------------------------------------------- ------------------------------------------------------------ ----------------------------------------------LQLPERAYCADVLY PMAIVGTAGRGITIYQLENQPQEFKRVESPLKFQLRCVTIFTDKKTNAPAGYALGSIEGR VAINYVNPTNPKDNFTFKCHR--VQDIYAVNCVSFHPVHGTLATVGSDGKFSFWDKDART KLKMSEAMDSPISSCAFNAGGQIFAYSCSYDWSKGHEGVDPQKMKPKIYLRACFDELQRS KK---------------------------------------------------------- ------------------------------------------------------------ ------------------EYKDKVKEYVSKYATEEALKETESSMSDFSENEAQDMELMDD QEILTTLKILVIGESGVGKSSLLLRFTDDHFDPEQAVTIGVDFKVKTLSVEGNKTKLAIW DTAGQERFRTLTPSYYRGAQGVILVYDVCNRNTFTKLDLWLNELEQYVTKQDVIKMVVGN KIDMDGREVSREDGLKFARKHHTLFIEASAKTKEGVQCAFEELVEKIIKTPGLWESDGLQ LSNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------RLKTFSIYRYN PDKPGEKPFIQKYDVDLNKCGPMILDALIKIKNEIDPTLTFRRSCREGICGSCSMNVNGL NTLACLCKIDENTKKASKIYPLPHMYVIKDLVPDMNNFYAQYQWIEPYLKKKDLKEEDIG KKSFEQSPEQRKLLDGMYECILCACCSTACPSYWWNQDKFLGPAIIMQAYRWIMDSRDDY KQQRLEKMQDRWSVYRCHTIMNCTKTCPKGLNPGAAVAEVKKMLSGGESTGIPYQDIKPN HSIYINNLNEKIKKDELKKALYAIFSQFGHILEIVALKTLKMRGQAFVIFKDVSNATNAL RSMQGFPFYDKPMRIQYSKKDSDIIAKMKGTFIERPKKRRGADANRRKKKGSANSIPEQP PHHILFLTNLPEETNEMMLSMLFNQFPGFKEVRLVPGRSDIAFVECETDQQAAAAKEALQ GFKITPSNAMVITFAKK------------------------------------------- ----------------------------YPMDNGIVRNWDDMLLLYDYTFGKDVLDINPH ECKILLTEPPLNPNKNREKMVEVMFEKYGFHSLYIAVQAVLSLNAQGLLTGVVIDSGDGV THICPVYEGFALHHLTRRLDIAGRDITKYLMKLLLSRGYAFNHSADFETVR--------- ------------------------------------------------------------ -----ADIDTRSEFYKHIVLSGGSTMYPGLPSRLEREIKQLYLERVLKGDTTKLSKFKIR IEDPPRRKNLVFLGGAVLANIAKDKDEFWLTRSDYEEKGLNVLSKL---MSPTIGKIIQC RAAVAWEPKMPLSFETIEVDPPKAGEVRIKILATAVCHTDAYTLGGSDPEGLFPCVLGHE GAGIVESIGDGVTTVKPGDHVIPLYIPQCRDCKFCSHPKTNLCSKIRGTQGKGVMPDGSS RLHCKGQDLYHFMGCSTFSEYVVCAEISVAKIPESAPLEKVCLLGCGISTGYGAALNTAK VEPGSTCAIWGLGAVGLAVIMGCKKAGASRIIGIDINSEKFSTAKEFGATECINPKDHES PIQQVLVENTDGGLDYTFECIGNVHTMRAALESCHKGWGESVIIGVAGSGQEISTRPFQL VTGRVWKGTAFGGWKSRDNVPKLVDQYLEGQLKLDEFISHNLPFNDLNDAFQLMHDGKS- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------TTGVVLDAGDGVTHAVPIYEGFAMPHSIM RVDIAGRDVTRYLQLLLRREGQNFYTSSELEIVRTIKERVCYLSINPQKEETVESERSQY QLPDGSMLEVGPSRFRAPELLFRPDLIGEECEGIHEVLAYSIQKSDMDLRKTLFSNIVLS GGSTLFKGFGDRLMSEVKKLAPKDLKIKISAPKERLYSTWIGGSILASLDTFKKMWVSKR EYEEEGIRAIHRKTF---------------------------------VFGVLLGSNKQG VLDVSNSFAVPFEEDEKDRDVWFLDHDYLENMYNMFKKVNAREKIVGWYHTGPKLHPNDI AINDLICKYCANSVLVIIDVKPKDLGLPTEAYIAVEEVHDDGTPTCKTFEHVPSDIGAEE AEEVGVEHQLRDIKDTTVGTLSQRVTNQLMGIKGLASKLEDIHNYLKEVVDGTLPISHPI LYQLQDIFNLLPNVSLEEFIKSTYIRTNDQMCVVYLASIIRSVIALHDLINNKLANRDSE KNDGKSDKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXKPISVRRIRVTDASQLPSDYSETPGGTLFSTTPGGTRLLYDRAFLMECRNSPLA KTPP-NLPNIPGVTSP-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------AGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPHHHPLLRLAWNKQ DPNYLATMAMDAMEVIILDVRVPCTPVARLSNHRACVNGIAWAPHSSCHVCTAADDHQAL IWDIQQMPRAIEDPILAYTAAGDLNQIQWSSTQPDWIAICYNNCLEILRVRSFSISSKVA VLGAAGGIGQPMSLLLKMNPHITKLALYDIVNTPGVAADLSHCSSPSSVTGHDGQDSLPQ CLKGCDVVVIPAGVPRKPGMTRDDLFNTNASIVQNLAENCAEYCPEAMLCIISNPVNSTV PIASEVYKKKHVYNPARIFGVSTLDVVRANTFIAEKKGLDVNAVNCPVIGGHSGVTIIPL ISQCTPPVSFPEDERAKLTTRIQNAGTEVVEAKAGTGSATLSMAYAGARFVNSILEALNG EEGIVECAYVASEETEAKYFATPLLLGKHGMQKNLGLGNLTAFEADLLKTALPELHGNIA KGEEFIAK---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TVKTPQIGDKFASRHGQKGTCGIRYRQEDMPFS VEGITPDIIVNPHAIPSRMTIGHLIECLQGKVSANKGEIGDATPFNDTVNVQKISNLLFE YGYHQRGNEIMYNGHTGRKLGAQFFLGPTYYQRLKHMVDDKIHSRARGPVQILNRQPMEG RSRDGGLRFGEMERDCQIAHGAAQFLRERLFECSDPYRVHVCNICGLMCIANLRNNTFEC RGCKNKTQISQVRLPYACKLLWQELMSMNISPRMMV------GGFCFDNCSRNAHMENGF QPPTATKTGTTIVGLIAGDCVILGADTRATSGNIVADKNCSKIHYVQDNIYCCGAGTAAD TDKVTQMASSYCELHRLNTGRQVRVVTPVRWLTQFLFRYQGHIGAYLIIGGYDASGPHLN SVSANGTAMDSPYLTMGSGSLAAMAVFESRFRNDLTKDEGIKLVRDGVAAGIFNDLGSGS NIDICVISKGTEYIRPYDIANVKGKRKGDYKPKIGTTPVLKTQV--IPYDIV-SKVTFKI TLTSDPKLPFKVLSVPEETPFTAVLKFAAEEFKVPPATSAIITNDGIGINPSQNAGTVFL KHGSELRLIPRDRVG-MAFTFAALVYIVALILTAFLIFFVIYHIIAFDELKTDYKNPIDQ CNSLNPLVLPEYGLHIFFNIFFLFAFQFGSLILNMPLIIYHIKRYINRPLMSGPGLYDPT SIMNADQLSLAQKEGWIKLAFYLLSFFYYLYSMIYVLVSSMGLLSILRKMKEKEREMRLL ILGLDNAGKTTILKKFNGEDIDTIAPTLGFNIITLEHRGFKLNFWDVGGQKSLRSYWRNY FEVTDGLIWVVDSTDRMRLQDCKQELNNLLVEERLSGATLLVFANKQDLPGAMTSEEIKD ALDLDNIKTHHWLIRDCSAVTGEHLIDGINWIIDDIASRIFTLD---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PGTGDLRDIGAGKGKYYAVNFPLRDGIDDESYEMIFQPVIAKVMEMYQPSAVVLQC GSDSLSGDRLGCFNLTLKGHGKCVEFIKKFDLPLLLLGGGGYTIRNVARCWTHETSIALG VDIANELPYNDYFEYYGPDFKLHISPSNMANQNTGEYLDKIKNKLFENLRMLPHAPGVQM ADIPEDALNEETNPDDRISIRASDKRMAVDEEYSDSEDEGEGKRRDKMSYKQKKRDQRNF ECNICLDTAKDAVISLCGHLFCWPCLHQWLETRPQRQLCPVCKAGISKEKVIPLYGRGNT SHQDPREKLPPRPQGQRSEPDNSTGFGGFGFSFQMSFGIGAFPFGFFASSFNFNDGRPAA PSPGSTQHSEEHFLSKVFLWVAMLFIFWLIMAMYARIHKQEKAHDDNIWSCAWAKNETDD TDIIASGSVDNTVKLWKWSDLELEHTLEGHALGVISVDINEQGNRVASCSLDAHIRIWDT TNGKQLKCIDAGPVDAWTIAFSPDGRFIASGSHNGKINLFGVDSGKRESQLDTRGKFTFS IAYSPDGKYIACGAIDGIINIFDITTGKLLEGHAMPIRGLCFSPNSQLLVTASDDSHIKI YDVQHANLVGNLSGHGSWVLNVSYCPDNNHFVSCSSDKTVKVWDAGSRTCVHTFTNHTDQ VWCSKYNNTGSKIVSVSDDRTLQIYEC--EEDEQFDDRYEAFFNNPSIDGWMLRKGMSEL HKMDLIPEPRIIEAIMRACRRNNDYALCVRYLETLHLKCGPRASEIWPYIEQELKPCMEE LGLLTLSEMGYDKPELAMADVMHM------------------------------------ ---------------------------------------------------------DAV VRLRGLPYGCSREEIAYFFTGLEIAPNGISLLHDNQGRTTGEAFVQFAHQDLAERAMNKH KDKIGHRYIEIFKSSMSELKNNFDESTGYTVHMRGLPFQCTEEDINKFFQPFSPVGIFIK MQDGRASGEADADFATHEDAEEAMTKDKNTIKHRYIELFFKDKTHPAVIRSSNIVAAKAV SDTIRTSLGPRGMDKMIQTGSGDTTITNDGATILKEMQVLHPCAKMLVELSKAQDVEAGD GTTSVVVIAGSLLDASENLLDKGIHPTTIAESFKLCSKKATEILESMSIPLELTDRESLL KNATTSLSSKVVSQYSNILSPICVDSVLKIIDNNDATTVNLKDIKVVKKLGGTIEETEMV EGLLLDSHSAGSGGPNRMENAKIGLIQFCISPPKTDMENQVVVSDYSQMDRVLREERQYI LNIVKQISKSGCNVLLVQKSILRDAVSDLALHFLAKKKILVVKDIEREDIPFICKTTGCK PIASLDHFTPEMLCSADLVECVQCGDGKVVKVTGIANPGKTISLLIRGSNKLVLEEAARS IHDALCVIRCLVKKKAIIAGGGSPEIELALRLFEYGNTLDGMEQYCFKEFAQALEVIPYT LAENAGLNAIATVTELRNRHAMGERNAGINVRNGSITNMLEENVIQPLLVSLSAINLATE TVACILKIDDVV------------------------------------TFADFDGVLYHI SNPDGDKTKIMVSISLKFYTELQKHGADELIKREYGDYLTTPEANYNVSLLFDENLPENK QELISKTALLKRNCFASVFERYFEIQQSHQTAIIHYRDDETMYVASKDDRVTVIFSTIFK DDDDVVIGKIFMEEFKEGRRSAMQAPQVLFSHKDPPRELDDSDARVGDNVGYITFVLEPR HATKDNTINLIHTFRDYLHYHIKCSKAYIHSRMRAQTTEFLKILNRAKPVVETVEWKTI- MIFCPTCANILVAEEGEQCYRFACNTCPYVYNVRSKISNRKYPKLKEVDDVLGGSAAWEN VDSTEETCPKCEHDRAYFMQIQTRSADEPMTTFYKCCNTACNHRWK-------------- ------------------------EILLKGHEWIQNEVKASGLRGRGGAGFPTGMKWSFM NKPDDGRPKYLVVNADEGEPGTCKDREIMRHDPHTLVEGCLVSGAAMGACAAYIYIRGEF YNESSNVQVAIKEAYEAGLIGKNACGSGYDFDVYLHRGAGAYICGEETSLIESLEGKAGK PRLKPPFPADVGVFGCPTTVNNVETVAVAPTICRRGGDWFAQFGRERNPDVLMDFDGLVQ AQTALGTAAVIVMNKDADLIKCIARLIEFYKHESCGQCTPCREGVNWMNKIMKRFVTGEA KHKEIDMIYEISKQIEGHTICALGDGAAWPVQGLIRHFRPLLEDRMTEF----XXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XMSADLQWLLIRNNSSYLLKGLNFSTEPNNLKSRHSFRYNGLVQKKTVGVEPCADGKGVV LVTK-------------------------------------------------------- ------------------------------------------------------------ --------------------------------KELIDMNLIQEKWTDLSLPIERLNDIFV IGEFSNQIDWLHFIALACSTLRDGISPSLQLICEILTLDPPGAAANIPYDSFRTIYKFLS KIDGDISADTISNVLTFLATIKEKQDGQIRPSNFLGPDCPPLS----SPNKDQMMEQIKS QIAIATAQELLQKISDKCFKKCITTPGTSLGNSEQKCVAMCMDRYMDAWNLVSKAYGQRL QRER-------------------------------------------------------- --------------------MYENQREQLANQSFNMEQSNYAIQSLKDTKSTVDAMKVGV KQFKKEYKNINIDNIEDLQDELEDMTEQANEIQEVMGRSYGMPEVDDDELEAELDALGDD LMFGEDSTYLDDALNAPLAPSNVPGAE--TNRDGVLVDEFGLPKIAA-MTPMTPATP-SP QLQNIVCTVNLTCKLDLKQIALQARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTG AKSEDQAKLAARKYARIIQKLGFAAKFLDFKVQNMVGSCDVKFPIRLESLVLTHGQFSTY EPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKVRQEIYEAFENIYPILKGFRKQ----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------HGSAWYNCNRF DEDDAKKARSAQEGSRAALTRYLHYYNRYMNHMQSLKFEHKLYAMAKSKMEEMQRHNMSW IEVQFLKKAVDVLCQCRQTLMYTYVFAYYLSKNNQSEIFEDNQHNLESATEQLSEYLERD ITADSLVDIKQKVQDKLRFCENRRVVLLKHVHEGYEKEFWDYQEXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAFSPR GDRGGGDRGGRGG-GRGG--GGRGG--GGRGGMRGGKSVVIEPHRHEGVFIARGKEDALV TLNMVVGESVYGEKRIAVEEGTKIEYRAWNPFRSKLAAAILGGIENIHMRPGSKVLYLGA ASGTTVSHVSDLVGPEGLVYAVEFSHRSGRDLINVAKKRTNIIPIIEDARHPHKYRMLVG MVDTIFADVAQPDQARIVAINSHYFLKNTGHIVISIKANCVDSTAAPEAVFADEVNKLRS EKIKPREQLTLEPYERDHAVVVGQYRAPAKK----------------GKGPGIGLGVAGS GLALAYGLYNCVYTVDPGHRSILYSRLSGVQNTVYPEGFHFRIPWFQRPIIYDVRTKPRK ISSPTGSKDLQMVNISLRILSRPNSTALQSVYRLLGRDYDERVLPSITNETLKSVVAKFN ASQLITQRQAVSLMIKRELTERAQAFHIIVDDVALTELTFGKEYTAAVEAKQVAQQEAQR AQFIVEKALQERQQKIVQAEGEAQAATLIGGAIRSNPGYLKLRKIRAAQSVSQVMSASRN RIYLNAKNLMLNINDTAFDDVFH------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------NDSVTKTKFDNLYCCRE SILDALKRTTDVMFGGKTVVICGYGEVGKGCASALKGMGSIVLVTEIDPICALQACMDGF RVVKLNEVVKYVDIVITCSGNKNILIREHMDKMKNGCIVCNMGHSNTEIDIQSLKTPDLT WERVRSQVDHIIWRDGKRMILLAEGRLANLSCSSMPSFNVSITAATQALALIELFNAPAG RYKEDVYLLPKKMDEYVASLHLPSFDAHLTELTDEQAKYLGINKAGPFKPNYYRY----- ---------------------------------------QHYASLFL------NALSAQN SNMGNNNM---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------SFALCPTELVKCRLQSITKDIVRTEGVKG LYRGLTPTLAREVPGYFFFFGGHSLTSYILSPYGCQNHNLGAGEVICGGMAGVSLWIAVF PADVIKSHAQVNEYGIMGLYRGLGPTLLRSFPATGALFLAVENTKRFLN----EFSRKAK QISKNIEKITKNTGQARYLVDAIGTSDDNENVRSNWNKIRHDTGTIVQNTFPLLRNLSTL QTDRKQRKIQKERLTDQLTQALNAFQSLQREAETKEKTSYQDVDLMILEERGKEISQLEE DISNINMTFQELGRLVHEQGEPITSIEDAIGDVHVETGKVELDKAVTNMNRARKKKLFCL ILLIIIIVIIIIILIIA-----VTKGILVSCDPAMKQYLKHLDEKNKLGRKFIIQDLDDT NLFISSDALPMLQQQIDEHLSKFHF---KKEGKQTSPQEAIQKLRETEEMLQKKADFLET KVTKELTIAKKRIALQALKRKKRYEKQLNQIDGTLSTIEFQREALENATTNTEVLSVMGD AAKALQTAHKNLDIDKVHDLMDNVAEQNELAEEISNTISNPIGFGNEVDEDDLLLELEEI EQEAINEKLLDIPHLPAVPSGEDEDLKELMQWAT-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------IISDLRAQIAG YLYGVSPPDNSQVKEIRCIVLPPQWGTHQTVHIPGILPDHEYLKEMEPLGWIHTQPNELP QLSPQDVSSHAKIMQENSSWDGNKTVVITCSFTPGSCSLTAYKLTPSGYEWGRQNTDKGN NPKGYLPSHYEKVQMLLSDRFLGFFMIPSHGSWNYNFMGVRHDPNMKYNLTLANPKEFYH EVHRPSHFLNFSSLEEGADREDHY--YTSTRPNLMIGKDTKVLCQGFTGKQGTFHSSQAI EYGTNIIGGTSPGKGGQLHLGLPVFNTVKEAKDELGVTASMIYVPPKMAAKAIIEAIDAE VPLIVCITEGIPQHDMVKVIHKLVRQNKSRLIGPNCPGIIKPGACKIGIMPGHIHMKGNI GIVSRSGTLTYEAVHQTSAVGLGQSLCVGIGGDPFNGTNFIDCLEVFLKDPETEGIVLIG EIGGDAEEQASEYLKQHNGSNAKPVVSFIAGVTAPAGRRMGHAGAIISGGKGGAHEKIQS LRDAGVHVTMSPAQMGTTMIEAMK----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFSKFVEIGRVAYIA YGKDAGKLCTIVNVITQSTVLIDGPCSGVLRQSMNIKHLHLTSITIIGPGARSGAVRKAW DAAEVSKKWSETTWFKKIAAR-------------------------------------KT CPLLLRVFCNTGRHHSLSEYSRDNTPGSELQIYTWKDATLKELTNLVKEVNVDSRKKGTY FDFSIVSPDFRNPSYRMRDIGTTCAGKKGQDDNVTLVSRNFEIGDHIDIAITPPR----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------KFYPPRLFELLDREIYVYRKSIGYRVPKNPDLGVDAERVR KEEQKKIDDSEPLNEEELLEKEELLRGFITWNKRDFQQFIKANEKWGRDDLDNIAREVEG KPPDEVMEYSGVFWERCHELQDIEKIMAQIERGEAKIQRRSSIKKALDAKMGRYKAPFHQ LRVQYGTNKGKNYTEEEDRFLVCMLHKLGFDKENVYDELRTIVRQAPQFRFDWFIKSRTA MELQRRCNTLITLIERENLELEEKEKAEKKK---------------EGLPEPHIEFSDDG TIKTVIEYELDENDKKVRTTKKYSVETKKVNISIAQRKKLKKFGESAEDLPGPNASTTID PVYIQFFSNKDYESEDPMAKLKITCRFCKGPHWSKQCPNKDSFEQIESVISKTSKYVAPS LRDGANKRGESMGSDEAATIRVTNLSEDTRENDLQDLFQPFGAIQRIFLAKDKVTGQSKG FAFINFNNKNDAQRAIDAISGYGYDHLILNVEWAKPSXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX---------------------------------------SPLKRSIDEYIKACYINL DKPSNPSSHEVVAWIKRILRVDKTGHSGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYV GVFKLHSAVDDLKKITSTVEQLTGALFQRPPLISAVKRQLRIRTIYEAKLIEYDPVKHLG IVWVSCEAGTYVRTLFVHYGLMLGVGGQMAELRRVRSGITEEKEGLVTMHDVLDAKWQHD HHQDETYLRRVVKPLEALLVSHKRIIIKDSSVNAICYGAKLMIPGVLRFSDGIEMNEQIV LVTTKGEAIALAISLMTTAVLATCDHGLVAKLKRVIMERDTYPRRWGLGPVAGKKKAMIK EGLLDKFGNANTKTPSDWVE-----------------------------------YKRQP SSSQLKSKQAINQAQRSGASVDTSKKWAAGQNKQHTITKNTAKLDRETEELHHETVSLDV GKIIQSARTGKGWTQKDLATRINEKPQVVNDYEAARAVPNNQVMAKLERCLGMKLRGKDK GKPI---MLKPKTLTQILSQANTGGVQSTLLLNNEGALLAFSGYGDKDARVTAAIASNIW CQFEKNGRVAFNEDRLQYVLMDCEEGRVVIAKVVNVLLCIYAKKDVGFGMLKAKAAALVE YLHDPLSRVTASAPATARIQSKKQTLTDAYAPPANFLEIDVIQPQGKKRFTDYEVRMRTN LPVFRVKESSVRRRYSDFDWLRKELERDSKIVVPSIPGKALEKQLPFRSDDGIYGDEFVE NRRSGLEAFVNRVAGHPLAQNERCLHMFLLDPQIDKNYVPGKVRSTRNFSARLAEVGVLE PTKLQGKYETGQLFLHRVFGYRGVILFPWMGQVHDRDLGPNNNREVKGRTHTYYQVLIDA RDFPHIRVGTESVTFLSYQEDGTLFSIPGLDYVAHEDAIPYSTTEKQPVLNHMFDKFLQF DPSYCAKDSLREWQDKHHSWLELTDVHRESTENIRVTVMPFYIGDVQQTRVYWWRYSIRL ENFGEETIQLRERHWRIFSLSGTLETVRGRGIIGKEPIFSKTQPAFQYTSHVSLQAPSGH MWGTFKMERKDGSNFEVRIPPFSLVSKSEDGXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXMDIFLMVRRKNTTIFIDAKDSINVVDLKKQLKGLTKLPHEN LKLFKDDKPLSFYNFCN--ARAQTPATVGMTYKDFETLEIAEFTSPPELPDVMKPQENS- -----HFVRYEAVMMRARFEENKDENVARAKQLLKNGQRELFLKKHPQTFQFGGSPGGCS YNQEPPVPDWILDTWHPLERAQYPHYFAKRHQRKLEFIERYEKKYGKAM----------- --------------------------------VPSTAIREISLLKELAHPNVVFLDNVLM QENKLYLVFEFLSMDLKKYMDSFDRDQFMDKMLVKSYTYQITEAILFCHKRRVLHRDLKP QNLLIDTNGVIKIADFGLARAFGIPVRVYTHEVVTLWYRAPEVLLGSHRYSTPVDVWSIG CIFAEMTTKKPLFHGDSEIDQLFRIFRILKTPTDETWPGVSTLPDYKPIFPKWDNFLLDQ SVSKDGIDLLQKMLIYDPARRISALTALQHPYFASRLFNLLGKVGMGLAIGGTVAQTAIY DVDGGERGVIFDRFRGIQPGVIGEGTHFLIPFVQKPILFDIRSRPRSVPTITGSKDLQNV NITLRILFRPMPSELPKIYSTIGLDWDERILPSIVNEVLKAVVAEFDASDLITQREAVSN RINEFLTARSKSFGITLDDISITHLTFGREFTEAVEAKQVAQQDAERARFLVEKEEQLKK AAIIKAEGDAHAARLIAVALQKAGNGLVELRKIEAAEEIAQQLAHSPGVVYLPEGQQTLL GLPMKVINANQSVKVPDNVSVSVKSRVVTVKGPRGTLTRDFKHLAVVIKK-EKDKLTVEK WFGIKKELAAVRTVCTHIKNMISGVLKGYKYKMRSVYAHFP------------------- ------------------------------------------------------------ -----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XX------------------------------------------------FQYNEQLGPP YHVLIDTNFINFSIKNKLDIIKSMMDCLYAKCIPYITDCVMAELEKLGAKYRIALKIAKD PRFKRLMCMHKGTYADDCLVQRVTQHKCYIVGTCDKDLKRRIRKIPGVPIMYLSHHKYSI ERMPDAYGAPK------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------HKGPIFA LKWNKKSNYILSAGVDKTTIIWDASSGHCHQQFAFHSAPALDVDWQNNNSFASCSTDQCI HVCRLGVDKPIKTFQGHTNEVNAIKWDPMGTLLASCSDDMTLKIWSMRQDTCVHDLQAHN KEIYTIKWSPTGPGTNNPNSSLTLASASFDSTVRLWDVEGGVCIHTLTRHQEPVYSVAFS PDGKFLASGSFDKCVHIWNVQTGTLVHSYKGTGGIFEVCWNHRGDKVGASASDGSVFVLD LRK--------------------------------------------------------- EKVAINVMFPCKYSNSGCSISLLHTEKTDHEETCEFRPYACPCPGASCKWFGSLDQVMPH LMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYDGVQQFYA IVQIVGTRKQADNYAYRLELNGHRRRLTWEATPRSVHDGVQSAIMNSDCLVFDTNIAQLF ADNDNLGINVTISMC---QTFQNEYMLMPPITRAYTTTCVLTTLAVQLELVSPFQLYFNP DLIFNHYQIWRLFTNFLFFGAFGFNFIFNMIFTYRYCRMLEEGSFRGRTADFFYMFLFGG FIMICVVNLVFLGQAFTIMLVYVWSRRNPYVHMNFFGLLNFQAPYLPWVLLGFSLLLGNS VVVDLMGIAVGHLYYFLEDVFPLQNGGFRILKTPSFLKMIFDERREDPNYEPLPPGGYEW G--MELISDQGYRIDGRTSNELRRIRCKMGVFQQADGSAYIEQGFTKVLAAVYGPHEVRG SKNRPDKAFINCQYSMATFSTSERKRRPRGDRKSVEMTQHLKQTFEAAILTTLYPRSQID IFVEVLQSDGGNYCASVNAATLALIDAGIPMKDYVCACSASFYRDTPIVDVNKIEENGQP ELIVGLLPKSEQIVFLAMNGRLHEDHLSRILDTASKGCKDISNILDIAVRDMTGNYYFAI VGHNDNPVFEMEFTPQSKATD-QKDDHRHLNQFIAHAAMDLIEEQMWTTNNMYLKVVDKF NEWYVSAFVTAGRMKFIMLHDVKTEDNIKNFFQEVYECYIKYSMNPFYEMNSPIKSAPFE KKVLFHGKKYL------------------------------------------------- ---------------------------IPEGKSVVFKWRGKPLFIRHRSEAEVERERAVD IETLRDPQRDEERVKKDAWLILLGVCTHLGCVPIANAGDFGGYYCPCHGSHYDASGRIRK GPAPLNLEIPYYEYTDENLVVVGMARQSTRSNDPKKVSGELFTLTYGSLVAQLIKDYESN VEVNKQLEKMGYNIGVRLIEDFLSRSNTGRCQDFRETADVISKIGFKMFLGITPVVSNWS PAGDEFSLLIENNPLTEFVELPTGHTDLNYSNILCGVLRGSLEMVQMDVAAWFVQDQLKG DNITEIRLKFIQRLEDAIPPGED------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------KRYGNLKNGVN DIKNHKWFATTDWIAIYQKKVEAPFIPKCKGPGDFSNFDDYEEEPLRISSTEKCAKEFEY FMIADTLLILFISIATALLGEGMTWLMVYRTEKYKKLKSEIEKQSKKLEKHKENLVESTE RSVKKKLERQEEKLKNNNRDLSLVKMKSMFAIGFAFTALLSMFNSIFDGKVVAKLPFIPI SLIQNLSHRNLSGEDYTDCSFIFLYILCTMAIRQNIQKVLGFAPSRAVNKQGGLFMT-XX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXX----------------------------------- --------------IELDGRKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKS FDNIRTWIRNIEEHASNDVEKMILGNKCDMTDRRKVSRERGESLAVEHTIKFMETSAKAS INVEEAFFTLARDIKAKMDRKL-EGESSCDRNVEMWKIKKLIKSLEAARGNGTSMISLII PPKDQISRVAKMLADELGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVIYCGT IVTDEGKEKKVNIDFEPFRPINTSLYLCDNKFHTEALTALLADDNKFGFIVMDGNGALFG TLSGNTRDVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAEVAVQLFISNDRP NVAGLVLAGSADFKTELSQSDMFDPRLQAKIIKIVDVSYGGENGFNQAIELSAESLSNVK FIQEKKLIARYFDEISQDTGKYCFGVDDSLKALEMGSVETLIVWENMDIVRYILKNHQSD EEKILYLKPEQEKDRTHFTDAETGVELEMVDSMALLEWFANNYKSFGATLEIITDRSQEG AQFVRGFGGIGGILRYQVDFQSLDNLDGFDDDYDLDD----------------------- ------------------------------------------------------------ ---------------------------------AVMITDKVENLKASVIVHGSDGWDRTS QVVPLAMLMLDPYYRTIKGFEVLIEKEWCSFGHRFQQHIGHGEDKKNDVNRSPVFLQFID CVWQISQQFPNAFEFNEFFLITILDHLYSCLFGTFLCN---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------NESGFEISSPDATCKVLITTIPPNIKK LEPDLHLDPKLMTNHLAAIRHARWFEENAAHSSIKVLIRLLRDLKSRFDGLEPMTPWMID LLAHYSIMNNPSRQPLPINVAFRRALQLLAAGFFLPGSAGISDPCENGNMRVHTCLTLEQ QDQVCFTSQTLLRVLSHGGYKQILGITANSGIAVEMSVWEGVVVTPSGKAYEK------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -QAQDNFMMMDDAVLCISFSRDSEMLATGGQDGKIKVWKIVTGQCLRKFERAHSKGVTCL NFSKDNSQLLSASFDQTIRIHGLKSGKTLKEFRGHTSFVNDVSFTSDGHSVISASSDGTV KVWNLKTTECSNTFKTLGGTSSADITVHSIHLLPRNVEQFVVCNRSNTVVIMNMSGQIVR SFSSGKREGGDFVACNVSPRGEWIYCVGEDMVLYCFSITTGKLERTLTVHEKDVIGLSHH PHQNLICTYSEDGLLKLWKPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------G KVKIQDILACSFLDDLLELRDEELSKDMQESNWFSAPSALRVYGQYLNLDKDHNGMLSKQ ELARYGTGTLTNVFLDRVFQECLTYDGEMDYKTYLDFVLALENRKEPQALQYLFRLLDVQ GKNHLNVFDLNFFFRAIQEQMKNHVADPVSFFDVKDEIFDMVSPKDPLKITLQDLINSRQ GDTVVSILIDLNGFWTYENREXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXX------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------DLAIRKSIPVSEVDPKEAKAIVVHGSDLRDYTPVQ LDEILANHSEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIA GSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLLFILCD IPLPLGTITILCIDLGTDMIPAISLAYEQAESDIMKRCPRDPLHDKLVNHRLIGMAYGQI GMIQASAGFFTYFVILAENGFWPSRLFGIRKEWDSKAINDLQDSYGQEWTYAQRKVLEYT CHTAFFVSIVVVQWADLCICKTRRNSIVQQGMLNRHLIFGLFFETTLAAVLCYTPGLDKG LRMYPLRWTWWIPAIPFSLVIFIYDEVRKYILRQRPGGWLENETYYSYANLSPVRKIAVG VSALGVALGIALEVNCVHPPSLSWSHKGMFQSLDHASMRRGYEVYKQVCAACHSMNFLAY RNLVDVIFTEEEAKKEAEEVLVTDGPDDEGNMFERPGKLADRFPNPYSNDEAAKAANNGA LPPDLSFIVNARHGGEDYIFALLTGYTDPPAGVTISDVQGYNPYFAGGAIGMTQQLYNEG IEYEDGTPATVSQMAKDVCTFLRWASEPEHDTRKRMGMKALAIALIVLLTYAKKHKWSTI KSQKIAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------ --EEGTTLGTYEGERNEQEERHGFGKAVLPIGDTYEGQYKNGKRNGHGVYRFRNGASYIG EYANAKKHG--------------------------------------------------- ----------------------------------------------------------MP DIMKLITKDLSEPYSIYTYRYFIHNWPKLCFLAMDGTKCIGAIVCKLDLHKKLARRGYIA MLATDENYRRRGIGTHLVMKAIRVMVADDCDEVVLETEITNKAALRLYENLGFVRDKRLF RYYLNGVDAFRLKLWLRYIDCLRFLIPSHGKKCLKESVHKNILVNGEYEITETPGQEVDL RIHDSKQYILFQKSKATKGKYSFTLDEFDTYEICFTSSMTAGGKGPDIEVWIDSKHGVEA KNYADIAKAEQLKPLEVELKRLEDLSESIVNDFAYMRAREEEMRDTNESTHTRVLYFSIF SMCCLLGLATWQVIYLRRFFKAKKLIE--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------ERLDLLKLFLNLLTSHLKGEPAEFQIDDTFSVPGVGTVVSGTTLSGSI KVNDTLLLGPDALGSFIPAVIKSIHRKRLPVKGVRGGQTASFALKKSQLRKGMVMVSPKL EPKACWEFEGDILVLHHPTTISVKYQAMVHVGSIRQTATIINMSKEHMRTGDKASVRFRF IKNPEYIRPDMRLVFREGRTKAVGSITTLYPHITANSRAQRASKKAE------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------QFSWD SAYIATGSMDNTCKIWDVISGECVETLTGHKDEVLDVTFDLTGQYLVTASADRLYNAITH AKLEGHAGEISKICFNPQGTRILTASSDMTARLWDTEKGDCLQVLEGHTDEIFSCAFNYE GNTVITGSKDNTCRIWK------------------------------------------- ----------------------------------------------IIKENYVVVYELLD EMLDNGFPLATESNILKELIKPPNLLRTLTDTVTGKSSTVSSTLPTGQLSNVPWRRTGVK YTNNEAYFDVIEEIDAIIDKSGSTVFGEIQGYVDCLIKLSGMPDLTLSFVNPRLLDDVSF HPCVRFKRWESEKILSFIPPDGNFRLISYHIGAQNMVAIPLYIKHNISFKDGGSGRLDIT VGPKQTMGKGVENVSLEIPFPKMVLNMTLAPTQGKYSFDPVTKIMSWDIGKVDSSKLPNI KGTINLQTGSAPPDANPTIQVKFTVNQIAVSGIKVNRLDMYGEKYKPFKGVKYITKAGKF QVRT-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------SYPVNPTRVVKGSTNPQSWEDFSRHNKNRADAEMISSR ALREALHHTLNQTDSDLSAKQAASDYAIRKRMHETQQALDELNWQKEKTENEMAELEEAI RRLNDAIAAKIKPMKLAQTRLENRTYRPGVDLCRDNVQYGLTDEVKQLETTILSLEEKLK QSQHALHNLEQILQHVNTQIRCKTNSIKLDEKCAGARNQL-------------------- ------------------------------------------------------------ --------------------LLVTGQVPTEAQVKAVSQEWASRAELPSFIVSMIDKFPDT VHPMAQFSAAITACSSESKYAKAYSQGVHKSTYWEYVYEDSMDLLAKLPPIAALIYRNLF RDHTSVGAIDMEKDWSYNFVSMLGYEDPQFTELMRLYLTIHSDHEGGNVSAHTCHLVGSA LSDPYLSFAAGMNGLAGPLHGLANQEVLVWITKLKYTIEELREFIWNTLKSGQVVPGYGH AVLRKTDPRYTCQREFALKHLPKDPLFKLVSDVYKITPDVLLEQGKAKNPWPNVDAHSGC LLQYYGMTEMNYYTVLFGVSRAIGCLSSLIWDRALGLPIERPKSFSTDKLIQAYSMPFVP PKVEKCIRCEKSVYANERTEAGGLIWHNLCFRCSQCDMKLTLNNYAQDKGTLYCKKHFQQ CVTSQNTQV--LFVHRDSPENNADKEWKFTPENLERAKAIIGNYPIGHERAAVMPLLDIA QRQNGWLPISAMHHVGDLLEMPYMRVYEVATFYTMYNRNPVGKYHIQICTTTPCMLGGIG SEPILNAIKAKLGIEVGQTTEDKLFTLVEVECLGACVNAPMIQINDNYYEDLTVDDVNEI LDELTAGREPKPGPR---NGRYACEPLSGLTSLIEPPRGPGFKVRDDL------------ ------------------------------------------------------------ ------------------------------------------------------------ -INKNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTAIDMWSAGCIF AELANAGRPLFPGNDVDDQLRKIFKLLGTPTDDVWPGMSQLPEYKSYPLYHTNVQVVPKL NSRGRELLSHLLICTPSRRVSSEEAMQHSYFNDINSSLKAENKFFVHTGPTLGVRYPLED DCDGWPLEYCEFHSNYDKAKEWVVENLSREMRVMYLKRQKRGGKGQIKPKKKAAPLGITL ARAKRGKNKSITVVCGLASYGIDLKKASKAFSNKFACSSSVTGNDEIVIQGDVSDDLFDF IPETYTEIPEDDIEYIGEVKR--------------------------------------- ---------------GYSHVYIPNKDILISDAGKLWVLDTLLARLKADGHRVLIYSQMTR MIDILEEYMWHRKHIYMKLDGSSKISDRRDMVADFQSNSDIFVFLLSTRAGGLGINLTAA DTVIFYDSDWNPTVDQQAMDRAHRLGQTKQVTVYRLICKGTIEERILQRAKEKSEIQRMV ISGGNFRPDVLKPKEVVSLLLDDDDMEKK------------------------------- -CENCDAYLNMKGNRDAVYDSTSSSFDGMVAMMSPEDSWVSKWLRLTRMVKGCYAISVTG SLPPGIIRELKRKGINYRERDHS--RFPQYLSEAAEQELRKIAYAIVAPGKGILAADEST GTIGKRFADIQLENNEEHRRQYRELLFTALSSYISGVILYHETLFQKTTGGVPFPQVLIQ QGIIPGIKVDLGVVPLLGTKNESTTQGLDDLSERCAQYKRMGCGFAKWRCVLKIDSHTPS YLAMKENANVLARYAMICQKNGLVPIVEPEILCDGTHDIYTCQKVTEKVLSFVYEALHDH HIYLEGTLLKPNMVTPGMQSSQKASPQEIAAHTTRALRRHVPPCVPGITFLSGGQTEEDA SINLDAINRKPWALTFSYGRALQASVIQAWKGNKENVKAAQNELLKRAKANSEGSLGKYA GGIAGAAGQSLFVANHAYYIQSLPKVVKRRIKALKKIQKQTVDIEAKFYEEVHELECKYA AQHVPLFEKRRNIITGDLEPTDSDCEWPSDEEEEEEKVAIQDEKDVKGISLFWLTLFKNV DMIAEMIQECDEPILAFLRDVSVEYKMGFNLHFYFDANEFFSNTVLSKNYIMRSTPDEED PLSFEGPEIIKCTGTKIMWNKDKNVTVKTIKKTQRHQSRGTRRTITKTVQKDSFFNFFSP PEVEDGEPEEEIEAILSADFEIGHFIRERIVPRAVLYFTGEALEMEEEGEDEENDLILLK EGTDSSQGKPQIVSNINACQAIVEAVRTTLGPRGMDKLMVDSRGNATISNDGATIMKLLN IIHPAAKTLVDIAKSQDAEVGDGTTSVVLLAGEFLKQCKPFIEDGVHPQIVIRGLNKATN LAVNKIKEISVKTKSRDEEQRSLLEKCASTALSSKLVAAHKDYFSKLVVDAVTQLDELLP LNMIGMKKIPGGALQESHLIEGVAFKKTFSYAGFEMQPKTYSNPKIALLNIELELKAEKD NAEIRVDNIEEYQSIVDAEWTILYDKLENIYKSGAKVVFSKLPIGDVATQYFADRDMFCA GRVSDEDLKRTIKACGGAMQTTASEMKLGSCESFEEIQIGNERFNVLKGCLNTKTCTFII RGGTEQFLEETERSLHDAIMIVRRTLKNDSVVAGGGAIEMELSKYLRDESRKIAGKEQLI IGAVAKSLEIIPRQLCDNAGFDATYTLNKLRHKHAGTWYGVDINNEDIADNFDAFVWEPS IVKINSITAASEACSVILSVDETIRNPKSSTP------------KRNKVIPNVHFHKDWQ RYVKTWFNQPARKIRRRNNRVKKARAVAPRPVAGPLRPVVRCPTFKYNSKARMGKGFTLD ELKGAGLNKKYAKTIGIAVDFRRRNKSIESLQLNIQRLNEYKAKLILFPKKMSKPKAGDA TEEEMKMATQLVG----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------SMVLVGNVCNKVAILVDDILDTCSTLLKAGEKILKC GATKVYAISTHGILSGPAAQRINQSSFENFVVTNTIPQANHLKECEKLKCIDVSMILAEA IRRTHNGESVSYLFSNVP-LKCRFYEQRFPEKEDVVMCCVRKVEQMGAYVDLLEYKDIEG MILLSELSRRRIRSIHKLIRPGRSACVVVIRVDQDKGYIDLSKRRVSAGDAEKCEEVYAR AKTVNSILTHSASILEFETDEQLEELYNSTAWYFDRKYGKVGSCYDAFK---TNPAALDE CGLEDNVKQVVIDNIKRRMTPQAVKIRADIDVACYKYEGIDAVKNALRAGLNSSQDEFPI KIKLIAPPLYVVTTQTLERQEGMARGQQKIQSQQKNAEKLAKMKTSSKKSAAAALVYSCD VCKSQMPDPKTYKQHFESKHSKCPLPECLKE-XXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMRPLTDEETKIFFE KLSKYIGENIKLLIDRPDGAYCFRLHKDRVYYLSEKLMKKAAHCARDNLVSFGTCFGKFT KSLKFRLHITALDYLAPYAKHKIWVKPSAEQQFLYGHHIMKSGLGRITENTPLYQGVIVL SMSDLPLGFGVAAKSTQECRHTDPMTLICFHQADIGEYIRSEETL-QERKFFVGGNWKMN GDKKSLDSIIKMMNESLLNTEVVCSPPTCYLEYVRLRMIGVAAQNCWKAEKGAFTGDISP AMIKDLGCEWVILGHSERRNVFGESDDLIGEKVSHALESGLKIIPCIGEKLDEREAGKTE EVVFRQMTHKDWKHVVIAYEPVWAIGTGKTATPDQAQEVHLALRKWLLDNVSADVAKKTR ILYGGSVTGKNCRELA-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------HNQEVQEAMIFENRHTPYTMETLRVGWEQLLTSVARNVNEVE NQILTRDSKGISNDQMEEFRKSFTHFDKSRNRQLDPKEFKACLVSLGYNIRGDKQGEADF QRIMAIVDPNRTNKVTFDAFLDFMTRETADTDTAEQVMQSFRILAGDKPFITADILRREL PPDQAEYCIHRMAPYTGRDAAPGSLDYTSFSTALYGESDLNKLSIDSLDLNDKRVLIRVD FNVPLKDGVITNTQRIDAALPTIRHALNSNAKSVVLMSHLGRPDGRRQSKYSLKPVAECL KSKLGRGVYFLDDCVGNNIEIACQNPPHGSVILLENLRFHIEEEGKGLDENGKKVKATDD AVAQFRNSLSKLGDVYINDAFGTAHRAHSSMVGVNLSSKASGFLLKKELTYFAKALDCPL KPFLAILGGAKVQDKIQLIFNMLDIVDEMIIGGGMAFTFLKVLHNMEIGNSLFDSEGASI VNKIMDKAAERNVKIHLPVDFVTADKFAENANVGYATLNDGIPSGWLGLDCGKESIKNMI PAIKRAKTIVWNGPAGVFEFKNFSQGTRAIMDAVVEVTQNGAITIIGGGDTATCCAVWGT EDKVSHVSTGGGASLELLEGK-----------MSSIPIKSWQPPLVTVETSMGIIILELY WKHAPSTCRNFAELARRGYYNQVKFHRVIKEFMIQTGDPTATGRGGASIYGKEFEDEISG DLKHSGAGILSMANSGPNTNGSQFFITLAPTQWLDDKHTIFGRVSSGLSVVARIGMVEVD SNSRPVDEVKIT------------------------------------------------ ------------------------------------------------------------ ----------------------------------QPLPGYSEDSSVGVISSVVQDSPHKI FIGGLPNYLNEDQVKELLLSFGPLKSFILVQDSATGLSKGYAFCDYVDQACAGLNNMQLG EKKLFVQRASLGAKNPQSAPVQIQVPGLNPQQLATEVLCLMNMISPEELMDEEEYEDILD DVREECNRYGRVKSIEIPRPIKGIEVPGCGKIFVEFSSLVDCQKAHQALSGRKFSSRVVV TSYISLDQYHRREFLVPLFDRVLVKRLAAETKTKGGILIPEKSQGKVLEATVVAVGPGMR NNNGEIIPPCIAPGDNVLLPEYGGTKIDLDEVEHHLFRESDILGKLERLKTQLPDIKSTL ELVKHMQNRKDDMVTHYQLYDCLYAKARIPPTDKVGLWLGANIMLEYSVDEAESLLDKNE AVKSLDNVETDLEFVRDQITTTEVNMARVYNWDVKRRQ----MADEALEKAGLYFDDLNK IRVLEPDCAQQTNELKEDCKEFLDKMIEFKSIVGSFISLVGDASKDVENEKMKAIGSRNL LKSITKQREAQQQQLIALISEKNMHLERLRIQHDALMQEETEQNEFIEQFILQK------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------DRDNSRSRGYGFITFRNSEDAKKALEQLNGF ELAGRPMKVGHVSERAGEYHHLDTDEMDRAGIDLGATGRLQLMAKLAEGTGFQIPQHAAN ALNMQPHNATPPIATQCFMLSNMFDPTINAANWETEIRDEVLEECNKHGGVLHVYVDKAS PQGNIYVKCPSITAAVASVQALHGRWFARKMITAAYVPLPNYHALFPDAMRLVQPLMPSY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------EEETEIS TCKKGQYFGELALLTHKPRAASAYAKGPTKCAVLDVNAFERLLGPCMDVMKRNIQDY--- ------------------------------------------------------------ ----------------------------------------------------------DY CTSHIHVLNMCLMVIKVSIHSRNWSHVISYYNKADLDTHI---KECPSSTVAQFKCAYAL AMLAAHNYKNVAKNLVQVNYDSCESIEILSTSDIAKYGTLCALASYDRHELYTNVISSAS FKLFLGQEPWLREILQSFHKSEYAKCLKILDEYKDQLLLDVYLADHVKTLYTQIRHRALC QYFVPYVSADMREMANAMNTSIVDLENELMQLILDDKIKARIDSHNKVLVAKYVDSRCAT FEKAFRDGKEFKRKTNAAILRCAMMKANIQIKSVSREESH-NEIATAP------------ IDKIEDVADQIFRHSNHFLPHIARLCLISTFLEDGIRMWFQWGDQRDYISESWGCGWFFG TLFVIINLLGQLGACVMVLSRQKVKIACGMLFGIIAFQTVAYQILWDLKFLMRNLALAGG VILILAESQAEGRSLFAGLPSLGENTPKTYMQLSGRIMLVLMFATLLRFEFSAGQFIQNL VGSALIVLIAIGYKTKLASLILVVWLSCLNCYFNAWWNIPDYKPMRDFLKYDFFQTLSVI GGLLLVVALGPGGYSMDEHKKKW------------------------------------- ---------------LSTLNMRIRRRLDLFANVVHVKSIPGLKTRHNDLNFVIIREQTEG EYSSLEHESVPGVVESLKIITRANSTRIAKFAFDYAVAHGRKKVTAIHKANIMKMSDGLF LECCKEVAQLYPNIEFENMIIDNCCMQLVSNPYQFDVMVMPNLYGNIVDNLGAGLVGGAG VVAGESFSSDCVVFESGARHTYASMVGRDVANPTATLLAAANMLNHINLGQYGDLIRNAV VKTIKLGKIRTPDMGGYGTRTDFTNAIIREI----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MLSQPQDSMELQHKQSK VAVTSLSFLSADVNNFVVGSEEGMVYSACRHGSKAGVADMFEGHQGPVTGIDTHQVPGSI DFSPYFVTSSFDWTVKLWNIKESMPVHSFEDNSDYVY----------------------- ------------------------------------------------------------ ------------------IEKQLTKAVQIVEDQVDAQIKKLDKLSEDDYETLREKRLAAL KKHSAQKSEWLSQGHGEYQELADEKEIFDAYKKSKNIVCHFFKNDTFRCKIVDKHLSHLA QKHLEARFVKVDVERCPFLVERLKIKFMPTIAIILNEKVSDYIVGFTDLGNHDEFSSEMM EWRLAQSKVINYAGDLSIPPDQKKKEKTIRGGDDDSXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMA SRKTPSDFLKQIIGRPVVVKLNSGVDYRGVLACLDGYMNIALEQSEEYVNGQLKNKYGDV FIRGNNVLYISTQKRR-------SLLLKKQLSELERTPVDGFSAGLVDDEDIYKWSVMIM GPPDTFYAGGLFKAQLIFPKDYPQKPPKMKFTSDIWHPNIDKNGDVCISILHEPGEDKYG YEKAEERWLPVHTVETILLSVISMLADPNDESPANPDAAKEWRERKDCFKKKVSRCVRKS E--TISPSLVVKKQTLKDFGSYVSECLPKYIQKAQVTYGGELELLIHPDGITPVMTFLKD HTNAQFTNLADIAGVDMPTRQYRFEVVYNLLSLRFNSRIRVKTYTDELTPLQSLYAVHKA ADWYEREIWDLFGVYFANHPDLRRILTDYGFEGHPFRRDFPLSGYVEVRYDDEVKRVVIE PVEMTQEFRKFDSATPWEMFPAHR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------FAKDVKNEFKMAFGATVEVKTSKEL KVQGCIGHCVSNNNASNVSDTELGIGGTNQWKICGLYPSNTLAFYFEVVNQHNAPIPQGG RGYIQFITQYQHSSGQKRVRVTTIPRNWVDASQNIPMVAAAFDQEAAVVLMARIAIHRAE TEDGADILRWLDRMLIRLCQKFGEYQKDDPASFRFNEQFTLYPQFMFHLRRSHFLQVFNN SPDESSYYRNKLNIEDLTQSLIMIQPILYSYSFNGPPQPVLLDTSSIKPDIILLMDTFFQ LVIYRGETIDQWQKAGYHSLPEYENFKQLLQAPEDDAQDILQTRFPMPRYVVTEAGKSQG RFLLSKVNPSTTHNNM-------------------------------MSTLTPEQQMKLL QDLEIEMMADMYNRMSSACQKKCIPPTFKESELSKGEAVCIDRCVAKYIEIHDRIGKKIT NMAVKDEESVKKL----------------------------------------------- ------------------------YFRSGEGFMCVFSIAESESFQATSDFREQILRVKND ENIPFLLVGNKADIEDIRQVTSEQAQARAKEWNVPYVETSAKTRANVDKVFFDLMREIRL RKNEKKSKKKRCTIL--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------RKHVLQVSTYQMGILMLFNL RDKLTYDEVRMESDIPEKDLLPAMQSLACGKIAQRILTKDPKTKDIEPDHVFSVNESFTS KLFRVKIQTVASKGETEPERKDTRNKVDEDRKHEVEAAIVRIMKARKEMQHNVLVAEVTE QLKSRFLPSPVVIKKRIEGLIEREYLDRKPEDRKIYTYVADKLNVFPSRMNLAIMKNKLK GAQKGHSLLKKKSDALTVRFRTILRKIIETKILMGDVMKDASFSLAEAKFTMGDFSANVL QNVNKAQMKVRTKFDNVAGVKLPIFEAFSEGSDSYMLTGLARGGQQIDKLKKNFAKAIEL LTQLASLQTSFVTLDEVIKITNRRVNAIEFVIIPKIEKTLSYINTELDEREREEFYRLKK VQAKKKQEK--------------VIKVCVTGAAGQIAYSLIGSVAKGDVFGLDQPLKLVL LDIPPMMGNLEGVVMEMQDCAYPLLEEVVATADPNVAFADIDVALCVGAMPRKEGMERKD LLKANAKIFEAQGKALNQFAKKTVKVVVVGNPANTNAFIISSYAPDIPKTNFSCLTRLDE NRAKAQIALKNEVKNVTIWGNHSSTQFPDIEHGTVIRTAINDDDYLNNEFIKCVQTRGAA VIKARKLSSATSAAKAICDHMRDWWFGTNEGEWASMGVCSDGYGIPAGLFYSYPLKINRS FQIVQGLDISNFAREKMDATAKELIEERDMASE--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------STNGELGGTAGHSH TPITATAEVEVVDETKCCMTTIRPFRCEDLLRFNNVNLDPLTETYGLPFYLQYLAHWREY FKVAESHTGEIMGYIMGKAEGPGDNWHGHVTALSVAPNYRRLGLAAKLMTLLENTSDNKN CYFVDLFVRVSNLVAVNMYKKLGYSVYRRVLEYYSGEQDEDAFDMRKALSKDVDKKSVIP LPHPVRPEDL--------------------------------LCEDLLSSVDQPLKVARD KISDAEYLLCDYNRDGDSYRSPWTNSYDPPLDDGALPSDRLRKLEIDANEAFKQYREMYF EGGVTSVYMWDLDHGFAGAVLIKKAGDGSKKIKGCWDSIHVIEVQEKSSGRMAHYKLTST AMLWLQTNKSGSGTMNLGGSLTRQIESDSQVSESNSHIVNIGKLIEEMENKIRNVLNEIY FGKTRDIVNSFRSTVPPKMDLLKNDLAAALRNRSQDDGDFDEVP-NLDDL--SGKVEIVS AADRVDPEKRITTHWLTKYERARVLGARALQIAMCAPVMVELDGETDPLAIAMKELKARK IPMIIRRYLPDGSYEDWGIDELIIT------------------FPLGKAFLAGASVVGMG GLCFYGMGLSKDLGAIDEIGLWPDYVRHRIQNTYMYFGSGIAITACLKSPTIMRLTTKNS TMAMIAAMALMMGSGIVTQMIPYENTAKHAAWITHAGIVGGVLAPICLIGGQLVMTAAMY TAGVVGSLSLLAVCAPSDKFLNMGGPLAMGLGVVFLSNIGAMFF-PASRLGAGLYSISIY GGLVLFGLFLLYDTQKVMYRAKMHPTYGVRQFDPINSSLGIYMDTINIFIRIVSILAGSN RKR-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXWDVQISRLSIIA KPLASKKLNKKILKCIKKALGIGIKMVQKCIRKGERGIVVLAGDVSPIDTICHIPALCEE LDLPYCYSPSKDVMGAYCGSNTLASVVMIKSNDDYKELYTDCTTQINALPSPL------- ----------------------------------------------------DLGWTQDN ALVQKMKQANDDECKKLDESIEDAEKNQGETEIREMLLKKAEYFCKIGDKENSIAQFRKA NEKTTTSGYRLDIVFHHIRIGLFYMDHDLIKRNIEKAHNLIEEGGDWDRRNRLKVYKGLY SLAIRDFKTAAQLFLDTVATFTSYELMEYKTFVAYTVLSAIISLERPDLRSKVIKGSEIL EVLHSLPDVKEFLFSLYNCQYDSFFQNLARVEQFMKEDRFFAPHYQYYVREMRILAYAQL LESYQSLTLKYMANAFGVTTSFIDQELSRFIAAGRLHCKIDKVSNIVETNRPDSKNYQYQ GTIKSGDLLLNRIQKLSRVINIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXMQAPQGITGCPPGLEYLAHIDQLVIKQQMEILELVTGWESANKYRVFNNVGQQVYFAA EESDVCQRQCCGPARGFIVHLTDNFGNEVLRVTREFKCCAGCCWCAECAFEVKVEAPVGQ VVGFIRQESWAPSYTIRSTVGYIEGPCCVCNSPWC-GDVEFPIKGTDIGKIAKQWTGTLA EFFTDADTFSVTFPMDMDVKLKAVFIGAIFLIDFMYFEQQQNXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------GVCTTEKQNFYVFDMTVHPLTNNLMKAALFK KVQDAVLTKWINDPHRMDTRILALIYLAHTSDVLENAF--LNDDDYELAMKRVRELLDLD SETESMKDGANEILWCVVAAFSKGAKMKKVTAENCEVCVAFLKKIDASLDTIDNHIRKQC KAASRTDKRLCYSIGATEDSATSVIRQVSKQLSYHKTVENICADLHKKDSQICEIRYEKE LDLSNTDLNKLKVKDLKKILADWEEQCKGCTEKSDYVNRVKELMPKHAPASA---ILNGF KLNWMNLRDANTGKILWQSHDDLSKKDXSSEARVPKKILKCRSVSREINFTSKEQMEHFR LEQKVLF----------------------------------------------------- ---------------MPKVVSRSVVCTDTKDQEEYQGEKPLYVYFCLCGQISLILDSPIE KLPMRRIDNARVIDSNKHAHKLTCEADETVYLKRAKGIEKQYRQKCKKCGLLLYYRHKNI ITFIVDGALKR-GDLQTDIYSQI-KPKKVMVTKHTKTMGKFSSVTVSTVDEEEEELEAKE IADSYAANAKVIEKQLLRKGMSKRKLIELA--DAGQKRTKGTLID----SRHLSQLKNVA SYSTMQFTFSSGSGTNVKQIDVPAVSGSFGILPDHVPALAVLKPGVLTVMEEDSSSKKFF VSSGSVTINDDSSVQILAEEAVPLDMLDASAIREGAAKAASDVASEVDKAKAMVAVECYE ALAKALECKYFVTELQSRLDESAKSKAVLELGHDMNNRKRINYLTSDLRLIEALSDPHIC DRILKYNVHAEREGSNRYAKGQSETMGTLHNLVNKGVKVDLGIPYDMWDQPSAEVTKMQK KCFHLSEMLEEDIEEWYYNFQKTLEQYVCVERYLKNHDRVFSSTDIVSESDVQTAMIAKD KFGGLNAVVNCAGIGVAALTYHHNRDRIHSLEDFSRTLQINTAGTFNVIRLGAKAMADNQ PNEDGQRGVIINTASVAAFDGQRGQAAYSASKAAIAGMTLPIARDLAYLGVRICTIAPGI FDTALLSSLPETVRKTLSSTVPFPPRMGQADEFAHLVQFLIENPYINGEVIRLDGALR-- ------------------------------------------------------------ ---------------------------HFYDTVKGSDWLGDQNAIQYMCEEAPKAILELE NFGMPFSRLESGQIYQRAFGGQSLDYGRGGQAHRACCVADRTGHSMLHTLYGRSLYYDTD YFVEYFALDLLMEDGECKGVIALCLEDGNIHRFRANNTVLATGGYGRVFFSCTGAHTCTG DGGAMVARAGIPNQDLEFVQFHPTGVYGAGCLITEGCRGEGGYLINSEGERFMERYAPTA KDLASRDVVSRSMTVEIREGRGVGPEKDHAYLQLSHLPPDQLAARLPGISETARIFAGVD VTREPIPVLPTVHYNMGGIPTNWRGQVIDYEGSDKIVPGLWAAGESACVSVHGANRLGAN SLLDLVVFGRACSLNIAEDARPGDTPPEMSQDAGEASVANIDKVRFSTGSVAAADLRLQL QKVMQNHAAVFRESSTLSEGVEKIDALWKDQDLKVSDKSMIWNTDLIETLELQNLMVNGI QTMYSAEARKESRGAHSHEDFKDREDEYDYARPLEGQEKRPFEEHWRKHTLSYTDIESGE TTLKYRPVIDDVLDREKCDWIPPKLRVY-------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GKR GKYKEAEPLCKRALEIRETVLGKDHPDVAKQLNNLALLCQNQGKYEEVEQYYKRALDIYI LRLGQDDPNVIKTKNNLASAFLKQGKYKQ------------------------------- ------------------------------------------------------------ -----------------------------ISPKPTEKNVREFSDDVLRAGKLQAGTNKCA SQSMGGVRHVADIKSEEMDKAGQGIIGAQAGNKLASQSGMSMGGVRHVSDIKSEEMDKAG QSIIGAQAGTNKLASQSGMSMGGVRHVSDIKSEDMDKAGHSIIGLQAGTNKLASQSGMSM GAVRHVSDVQSAEMDAGQSIIGAQAGSNQFASQTGMTMGGTRHAADMKTNDMAGKGIIGA QAGTNQYANQSGMTMGGVRHAGDIGVDDIASHGVINLQMGTNQGETQSGLSFGGRRDI-- EVISFGIEPVYCHAWNADRSELAIPNNEEAKIYRNEWQHVDTLKEHVQRITGIDWASKTD RIVTCGADRNAYVWPCLVILRFNRAATCVKWSPLENKFAVGSGARVISVCYFELENDWWV SKKIKKPLRSTVTCLDWHPNNVLIAAGSTDFATRIFSSYVKEIESKPSTTLWGKKMPFGA LLADFMSSNGWVHDVSFSASGDKVAWVSHDSTISVVDASLKTDYLPLMSCSWINSNEIIA AGCDCSPIRFNLDDDTIKSIGKLDEATVSAMQLFRSMDKRGQLLDTVHQNTITQISIHSG DKDKAEKISTSGIDGRIVVWN--------------------------------------- ------------------------------------------------------------ -------------------------RVNRKISPDNRVHCCLYFISPNGHGLKAIDVEFMK KLHDKVNIVPLIAKADTLTPDECREFKKTILNEIAQHNIKIYEFDDEEEIKNHKKLKDRV PFAVVGSNTVVDSQGKKVRGRIYPWGVVEVENLEHNDFIALRNMVIRTHMQDLKDVTNNV HYEKFRYNKLASVNKSPLLQMEEERKEHTNKMKKMEAEMEQVFEMKVKEKKQKLKDSEAD LQRRAEQMKKQSEQRQRELDEKRNQFSKEKLAWEEQYQMARRYDSRTTIFSPEGRLHQVE YAMEAIVNAGTCLGILAKDGILLAAEKRITNKMLDKVSYSEKIYKLNEDIVCSVAGITAD ANVLVMRLRDYAQRYELNYHEPMPLEDLVRDLCDIKQAYTQFGGKRPFGVSILYMGWDKH YGYQLYHSDPSGNYSGWKAKCIGKNYSAAESILKIEFKNKEPTLEEALKVAIKVFNKTLD TNKLTPERVEITKLYRKNDQTFIETLSDEVVQVQIKEVDDAEAESGTSKK---------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------DPVRCNSVEEIKALRSAHDQFKASLSAAEADFNQLGALDEQIR SFNVGSNPYTWYSMSALDKTWQSLQQIIADRDDELAREQHRQEENDVLRKKFAQAANAFH GWLTDTRTAMMEGTGSLENQLEATKKKSEEVRAQRPQLKHIEELGALMEERLILDNRYTE HSTVGLAQQWDQLEQLGMRMQHNLEQQIEACNRSGVSEEALREFSMMFKHFDKEKTGRLD TQDFKSCLRALGYDLPVYEDGEKDPEFESILDQVDPNRDGYVSLQEYMGFMISRETENVQ SSSDVEAAFRALTSGEKPYITAQELYANLTKEQADYCISRMTPYEDNAGRIVPDTYNFVE FVKEKFVNAIQCYQCDSKQDASCPADGRFDKHMNALVDCNSLQAHTPGTFCMKITRQSPG WGAWKKTTRRCGSRSDTGVAWGCRWLYEDNGVFKETCYCDDAHGCNHSTLIDTEDCDNPQ LVSNYVNDIYSYMRVLEQKEISGRMRSILVDWLVQVHLRFHLLQETLYLTVSIIDRYLQN DVVRNRLQLVGVTSMLIASKYEEMYAPELSDFVYITDEAYNKNDIKKMECSILRALDFQL GRPLPIHFLRRNSKAAEVDAKLHTLAKYLMELTIVDYESVVFMPSEVAAASLCLSMKLLE WEDTVTFYSTYTEKQLEPVMKKICKLILIKLTAIKNKYHSQKFMRISSIPELKNNIITEL A----------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------------------WLT LALKSLAIINSRQHCVNVLVTTTQLVPALAKVLLYGLGGVFSIENIYSATKIGKESCFER VLSRFGRKCTMVVVGDGRDEELAAKQMNWPFWRISNHSDIAALHHALDLEFL-------- ------------------------------------------------------------ -----------------------------------------------------LACKEAC KYIQEQMTISTDELGRDSIINAAKTSMSSKLIGCDSDFFAELVVDACTAVKTTDNKGLAK YPIKAVNVLKAHGKSMKESVLVNGYALNCTIASQAMPTCVKNAKIACLDFGLMKAKMKMG VQLLVEDPEQLEEMRKRESDITKERIMKVLGAGANVVLCTGGIDDLCLKYFVEAGAMGVR RCKKTDLKRIAKATGATMISSLANLEGEESFESTLLGSADEVVQERICDDELILINGPKA RTAASIILRGANDAYCDEMERSIHDALCVVKRVLESKTVVPGGGAVEAALSIYLENFATS MSSREQLAIAEFAKSLLTIPKQLAINAAKDTTDLVAKLRAFHNISQTKPENVDLKWVGLD LLEGVVRDNKKAGVFEPAISKIKSLKFATEAAITILRIDDMIKLAPEEKQGRGH------ ---SGDNAYLLVSKNVLNQYLVEKKDLTIQYIVYNIGTIAARNVQLKDEGFPTEDFEVVH GSLNVNWPRIHPESNVTHSVIVRALKSGYYNFTSAEVTYLATQEDPHVAFSSAPGQGGII NSKDYDRKFSPHIVDWIAFAVMTLPSLGIPYLLWNSSKSKYDS-KAKKS----------- ------------------------------------------------------------ ------------------IHEKEENWVEAANVLAGIPLETAQKQYPNDYKLSTYLRIARL CLESENTANAESYVNRASLLQSETQNLELQISYKACYARVLDFRWKFIEAAQRYNELSYQ EIVAEDERITALTKALVCTILAGAGQQRSRMLATLFKDERCQQLPIYGILEKMYLDRIIR KNDLVEFETNLQEHHKAITTDGSTILERAVIEHNLLSASKLYINITFCELGSLLGITAAR AEKIASKMITEGRMQGDIDQIESVLHFEAREALPNMDKHIQSLCMQVNSIIDRIAESVPD WVVKTQEVKM-------------------------------------------------- ----------------------------------KIDDTIRYLSLHDNKYIRYFPGHTRK VVTLCMSPIDDTFISGSLDKTIRLWDLRSPNCQGLMNLPGWPVAAFDPEGLIFAAGVNSE SLKLYDLRSFDKGPFSTFKMQKETEAQWSSLKFSPDGKLILITTNGNVIRLVDAFNGSPL QTFCGHLN-KGLSLEASFSADSQFVFGGSADGKIHVWSTDTGSRVTVLNYDSPGPVQCVQ FNPKYMMLASASNHMAFWLPNIDEENVLVEKHGEKQNVGLIKLNRPKALNALCEALMRDL KCAVEDLEQDSDIGCMILTGSEKAFAAGADIKEMQPMEFPDTYSSNFLSHWDFISHTKKP IIAAVNGFALGGGCEVAMMCDIIYAGAKAKFGQPEILLGTIPGAGGTQRLTHAVGKYKAM EMVLTGNFINAEEAKSIGLVCQIFPPEDLISETVKTAEKIANQSQLIQKMAKEAVNAAYE LTLHEGLRFEKRLFHQTFGTFDRSEGMTAFVEKRAAEFQN >Tubifex_tubifex MTDRKAVIKNADMSEDMQQDAVDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAILLFKSGLGLQLRQFQTSSINRDIDQAAKYIGAGAATV GVAGSGAGIGSVFGSLVIGYARHPVLKQQLFSYAILGFALSEAMGLFCLMMAFLILFAFM AQYKDVGKVPEPVIHRIRITLTSRNVKSLEKVCADLIRGAKEKQLKVKGPVRMPTKTLRI TTRKTPCGEGSKTWDHFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADMDQVM QYVEPAKQFAKDSIRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNII VMATPMSKKRKFVQDGVFKAELNEFFTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVL GEKGRRIRELTSVVQKRFNFPEGTVELYAEKVGTRGLSAIAQAESLRYKLIGGLAVRRAC YGVLRFIMESGAKGCEVIVSGKLRGQRAKSMKFVDGLMIHSGDPMNDYVDQAVRHVLLRQ GVLGIKVKIMLPWDPSGKIGPKRPLPDHVSILDPKDQPAPEQPYSEQKGAKMSKRGRGGS SGGKFRISLGLPVGAVINCADNTGAKNLYIISVHGIRGRLNRLPAAGSGDMVMATVKKGK PELRKKVMPAVVIRQRKAIRRKDGVFIYFEDNAGVIVNNKGEMKGSAITGPVAKECADLW PRIASNAGCIRKAKVAKITLGPQLAEGENNFGVAHIFASFNDTFVHVTDLSGSETIVRVT GGMKVKADRDESSPYAAMLAAQDVAERCKALGITALHIKLRATGGNRTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRLMGKPHGLRTARKLRDHRRDQRWHDKD YKKSHLGTRWKSNPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP NDGCLNYIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVASVSLLALYKEKKERPRSDAA ATIRTRKFLTNRLLNRKQMVVDILHPGRATVPKTEVREKLAKLYKTTPDVVFCFGFRTNF GGGRTTGFALIYDSLDFAKKFEPKYRLARHDARKQRKERKNRQKKVRGTKKAKVGAMPRI QLNSSKTYSTPRRPFEKERLDQELKLIGEFGLRNKREVWRVKYALTKIRTAARELLTLDE KDQRRLFEGNALLRRLVRIGVLDESKMKLDYVLGLRLEDFLERRLQTQVFKLGLAKSIHH ARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLKSPYGGGRAGRVKRKNAKKAQGGA GAMGNIFEKLFRGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVGEAREELMRMLAEDELRD AVLLVFANKQDLPNAMNAAEITDKLGLHSLRQRNWYIQATCATSGDGLYEGLDWLSNQLK NQKMPLYKDLLHPSVDDEKRKCKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVVCA GCSTVLCQPTGGKARLTEGCSFRRKQHMVRMNVLADALRSICNAEKRGKRQVLIRPCSKV IVKFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRINKCSVISPRFDVKMKDLEHWTAYL LPSRQFGFLVLTTSGGIMDHEEARRKHLGGKILGFFFMGRMHTPGKGISQSSLPYRRSVP TWLKLTSEDVKEQIFKLAKKGLTPSQIGVILRDSHGVAQVRHVTGNKILRILKAQGLAST IPEDLYCLIKKAVSIRKHLERNRKDKDGKFRLILVESRIHRLARYYKSKKVLPPVWKYES STASTLVSIAELPHIKLFGKWSSEDVNHSDMSLADYIAVKEKHAKFLPHSAGRYQAKRFR KAQCPIVERLTDSLMMHGRNNGKKLMAMRIVKHAFEIIHLLTGENPLQVVVTAVINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAISLLTTGAREASFRNIKTIAECLADELINAAK GSSNSYAIKKKDELERVAKSNRMNEQMTLRGTLQGHGGWVTQIATTPQYPDMILSASRDK SLIVWHLTRDSSYGIPRKSLHGHGHFVSDVILSSDGQFALSGSWDHTLRLWDLSSGQTTR RFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIEDCHTDWTSCVRFSPNT QNPIIVSSGWDRLVKVWNLTNCKLKTNHYGHTGYVNTVTVSPDGSLCASGGKDSQAMLWD LNEGKHLYTLDGGDTINALCFSPNRYWLCAATGPSIKIWDLEGKVVVDELKPEVMGTTSK APTCLSLAWSGDGQTLFAGYTDKLIRVWQVSMVSRMREYKLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKVVEIEGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTFNDLQDLRDQILRVKDTDDVPMILVGNKCDLEDERVVGKLARQWNSAFLETSAKSK INVNEIFNDLVRQINRKNPEAMAEEKK-ADEHINLKVTGQDGSVVHFKIKKNTPLRKLMS AYCERTGVKMGSMRFRFDGQPINETDTPAGLDMEDGDAIDVFQQQTGGMSTLPLNPKPFL NALTGKPVMVKLKWGMEYKGYLVSVDGYMNLQLANTEEYIDGALSGNLGEVLIRCNNVLY IRGVEDDDEEGEMKEMSDTEGDDVPAAATAPGSMDLNTAIQEVLKTALIHDGLARGLHEC AKALDKRQAHLCVLANNCDEPMYVKLVEALCAEHGINLIKVEDNKKLGEWSGLCKIDKDG KARKVVGCSCVVVKDYGKESQAWDILNEYFKSRKMATLRKKLVIVGDGACGKTCLLIVFS KDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSI DSPDSLENIPEKWTPEVRHFCPNVPIILVGNKRDLRNDEMTKRELMKMKQEPVRPEEGKA VAEKISAFSYLECSAKTKDGVRQVFEMATRAALQTKKKRKTGXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMYSVSAKIVKPAGEKPDDFEASISQ ALLELEMNSDLKAQLHDLTFSSAKEIDVQNKKAIVIFVPVPQLRAYQKIQTRLVRELEKK FSGKHVVFIAQRRILPKPTRKMRRKNKQKRPRSRTLTAVHDAILEDLCFPSEIVGKRIRI KLDGTRLIKVHLDKAQQTNVEHKLETFTAVYKKLTGKDVVFEFPEFVLGRGGFRGGFGGR GRGRGRGRGRGKEGDKEWVPVTKLGRLVKDLKIKTLEEIYLFSLPIKEFEIIDHFLGSTL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDFNGHVGLGVKCSKEVATAIRGAIILAKLSI VPVRRGYWGNKIGKPHTVPCKVTGKCGSVLVRLIPAPRGTGIVSAPVPKKLLHMAGIDDC YTAACGQTATLGNFAMATYNAIANTYSYLTPDLWKETVFVKSPYQEFTDYLAKMSGGLDT LSLREDDVIKFLACGTHLGATNCDFQMEQYIYKRKSDGIYIINLKKTWEKLLLAARAIAA IENPADVCVISARPYGQRAVLKFSSHTGSTPVAGRFTPGTFTNQIQAAFREPRLLVVTDP RQDHQPVTEAAYVNIPVIALCNTDSPLRYIDIAIPCNNKSIHSIGLMWWLLTREVLRLRG SISREVPWDVMVDLYFYRDPNEESKEDVVTDWAAEASVAPAAVAAKDWSATDTGNWAAST ETSDWGGMKFNKDVSGSRRKNRKRHFTAPSHIRRRIMSSPLSKELRTKHNVRSIPIRKDD EVQVVRGHYKGQQVGKVVQVYRKKYVIHIERIQREKVNGATVNVGIHPSKVVIVKLKMDK DRKAILERKARARSAGKHTEESITPASSTTVGTTVRQRKTTNSGASSAGMWRFYTEDSPG IKVGPVPVLVMSLLFIASVFMLHIWGKYTRGKREGKKKTVTNEVVTREYTVNIHKRIHGI GFKKRAPRAIKEIRKFAEKMMGTPDVRIDTRLNKHMWSQGIRHVPYRVRVRLARKRNEDE DSPNKLYTLVTFVQVPTFKGTQTVNVEAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNAEKLKQRIGGKGSARRKKKVIHRTNTTD DKKLQVSLKKLGLTTIPGIEEVNMIKEDGEVIHFNNPKVQASLAANTFAVTGHAEIKQLS EMLPTILSQLRAENFSSIKKLATKAAEGE-DDDEVPDLVENFDEASKDEMTRYSLDAENA SKSAKARGSHLRVHFKNTRETAQNIKHMHLRRAVAYLKNVIGHKECVPFRRFTGGVGRCA QAKAWGATQGRWPKKSAEFLLQLLKNAESNAEFKGLDCDHLVIEHIQVNRAPKMRRRTYR AHGRINAYMSSPCHIEVILAEKEQAIAKPAKKKVSQKKLKKQKMMMREKKTGPKPELTEE QKQEIREAFDLFDADGTGTIDTKELKVAMRALGFEPKKEEIKKMIADIDKEGTGTIDFND FLTMMTVKMSEKDSKEEILKAFRLFDDDETGKISFKNLKRVAKELGENLTDEELQEADRD GDGEINEQEFLRIMKKTSLYMGISRDKWHKRRPTGGRQAQIRKKRKFELGRPAANTKLGT RRIHTIRTRGGNKKYRALRLDAGNFSWGSEAISRKTRVIDVLYNASNNELVRTKTLVKNC IVSVDCTPFRTWYEAHYALPLGKKKGAKLTPEEEQRINKRSKKAQRKYDARKKVAKVEPA LEEQFASGRLLACISSRPGQCGRCDGYILEGKELEFYVRKIKAKKGKMSLVIPEKFQHIL RVMNTNIDGRRKIAFALTAIKGVGRRYSNLVCRKAGVDLSKRAGELSEEEVEKVITIMSN PRQYKIPDWFLNRQRDIKDGKYSQVMSNILDSKIREDLERLKKIRAHRGLRHFWGLRVRG QHTKTTGRRGRTVGVSKKKNSATDSDGDDSAPDLEEAAQAAGLTDELVSKAKQSRSEKKA RKAMSKLGLKQIPGVSRVTVRKSKNILFVISRPDVYKSPASDTYIVFGEAKIEDLSQQAQ MAAAEKFKADEEIDESGIEAKDVELVMSQASVSRAKAVRALKNNQNDIVNAIM-GRVRTK TVKKAARVIIEKYYTRLTLDFHSNKRICEEIAIIPSKKLRNKIAGFVTHLMKRIQKAPVR GISIKLQEEERERRDNYVPEKSAIDEIDPDTKEMLKLLDMANIPNLQVTQPMANVXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMRDLRILKL CLNICVGESGDRLTRAAKVLEQLTGQQPVFSKARFTVRSFSIRRNEKIAVHCTVRGAKAE EILERGLKVREYELKKGNFSATGNFGFGIQEHIDLGIKYDPNIGIYGMDFYVVLGRPGYN VSKKRHATGSIGFQHRVTRDEAMKWFQQKYDGVLLPGKMGIKFLEFVKPFCAVLPEIQKP ERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGIS PIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMVITVGQAIVYVMTGMYGLPSE IGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSP---- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------LSPPETFQHVLEDPIHAVLYITFMLGSCAFFSKTWIDV SGSSAKDVAKQLKEQQMIMRGHREQSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIG SGTGILLAVTIIYQYFEIFVKEQSEMGGVGTLLFQNERAFQKQPTVFLNKKKTAVPRYTR SVGLGFKTPREAIEGHYIDKKCPFTGDVSIRGRILTGVVLKMKMQRTIVIRRDYLHYVRK YERFEKRHKNLSVHLSPCFRDVQIGDIVTVGECRPLSKTVRFNVLKVTKGTGSKKSFQKF MVNVPKQRRTFCKGKKCRKHTLHKVTQYKKGKDSLFAQGKRRYDRKQSGYGGQTKPIFHK KAKTTKKIVLKMECTECKFRKQLPIKRCKHFELGGDKKKKGQMIQFMGRVIRSQRKGAGG IFKAHTKNRKGAPKLRAVDYAERHGYIKGVIKDIIHDPGRGAPLARVMFRDPYRYKQRIE LFIAAEGMHSGQFLYCGKKANLQVGNVLPVGAMPEGTVVCNLEEKTGDRGRLARTSGNYA TVISHNPETKRTRVKLPSGTKKVIPSSNRAMVGIVAGGGRIDKPVLKAGRAYHKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGKASTVARDKSAGRKVGLIAARRTGRLRGTKQLTG KAKRTKKVGIVGKYGTRYGASLRKDIKKMEVTQHGKYTCSFCGKECMKRKCAGIWTCKSC RKVVAGGAYVYSTTAAATVRSTIRRLKETKEMGRRPARCYRYCKNKPYPKSRFCRGVPDP KIRIFDLGRKKAKVDEFPLCIHLVSDEFEQISSEALEAGRICANKYLVKFCGKDAFHLRV RVHPFHVLRINKMLSCAGADRLQTGMRGAFGKPLGTVARVDIGQIIMSVRVKDAHKEKVI EALRRAKFKYPGRQKIHVSRKWGFTKFDRDQYEPMRADGRLVPDGVGVQYKPSHGPLSKW MQAQKVTKILGRTGSQGQCTQVRVEFLDESSRSIIRNVKGPVREGDILTLLESEREARRL RMTKGTSSFGKRHNKTHTLCRRCGGRCYHIQKKTCSRCGYPAKRMRKFNWSEKACRRRTQ GVGRMRHLKKVFRRFRNGFREGTVAKKRIAMVDDRASSKELDQWVEQLMDCKQLTENQVK ALCEKAREILAKESNVQEVKCPVTVCGDVHGQFHDLMELFKIGGKSPDTNYLFMGDYVDR GYHSVETVTLLVALKVRFKDRITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHSNGLTLVSRAHQLVMEGYNWSHEKNVVTIFSAPNYCYRC GNQAALCELDDTLKYSFLQFDPAPRRGEPHVTRHTPDYFLMGAYKYIQELYRKKQSDVMR FLLRIRVWQYRQLAAIHRASRPTRPDKARRLGYKAKQGFVIYRIRVRRGGRKRPAPKGQV YGKPKSVGINQLKNQRSLQAIAEERVGRKCRALRVMNSYWVGEDSSYKFFEVICIDPFHS AVRHDPDAQWLCKPVMKHREMRGLTSATKKSRGLGKGHGYSKTIGGSRRACWKRRNTLEM HRKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGKSSKLLQHINYRMRCQL QDGRTFIGTFKAFDKHMNVILGDCDEFRKVKPK-SKTREEKRALGLVLLRGENLVSMTVE GPPPAEEGMARVPIPGASGGPGVGRAAGRGVPA-QGLAGPARGVGAPPPQMMQPQPGMMR GGPPDNIPSFKLVLVGDGGTGKTTFVKRHLTGEFEKKYIATLGVEVHPLVFHTNRGPIRF NVWDTAGQEKFGGLRDGYYIQGQCAIVMFDVTARITYKNVPNWHRDLVRVCENIPIVLCG NKCDVKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLTGDPNLEFVAMPA LAPPEVEMDPAMASKYEQELQVARETALPDEDDDLXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXLSFTENFALSGAAAIISKTAAAPIERVKLLIQNQGEMMKAGRLDKPYKGVIDCTV RTFKTEGILPFWRGNLPNCIRYFPTQALNFAFKDKIKAMFVMNKNDPYAVKFSKNVVSGG IAGAMSLVFVYSLDYCRTRLASDAKASKKRQFNGMIDVYVKTMKSDGIVGLYRGFVVSCV GIIVYRGCYFGFYDTLKPIVLGDHAGLMVSFMLGYVVTITSGLISYPIDTVRRRMMMTSG EAVKYKGSIDCAVKVIKTEGFMSLMRGAGANILRGVAGAGVLAGFDKFKELYVRWRIMSD MSDLDRQIEQLHKCEIIKESEVKALCAKAREILAEESNVQRIDSPVTVCGDIHGQFYDLK ELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQV YGFYDECLRKYGSITVWRYCTEIFDYLSLSAIIDGTIFCVHGGLSPSIQTLDQIRAIDRK QEVPHDGPMCDLLWSDPEDTQGWGVSPRGAGYLFGSDVVQQFNTANSVDLICRAHQLVME GYKWHFHETVLTV----------------------------------------------- XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSIGV PIKILHEAEGHIVTCETNTGEVYRGKLVEAEDNMNCQFSAVSVTYRDGRTAELENVYIRG SKIRFLILPDMLKNAPMFKKVGAGRGKSAILRAAARGRGRSFSGPPRGGMQNDAGEYVDM YIPRKCSFSNRIIAAKDHASIQINIAEVDESTGRMTGQNKTYAICGEIRRMGESDDCLVQ LGKRDGLISKMARGPKKHLKRTNAPKHWMLDKLGGVFAPRPSCGPHKLRECLPLAIFLRN RLKYALTYDEVKKIVNQRLVKVDGKVRTDKTYPAGFMDVITIERTNENFRLIYDVKGRFT VHRITPEEAKYKLCKVKKLLVGLKGVPSIVTSDGRTIRYPDPLVKSNDTVRIXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXX----------------HLFQVEYAQEAVKKGXTAVGVR GDNIVVLGVEKKAVAKLQEDRTVRKIALLDDHVALAFAGLTADARILVNRARIECQSHRL TVEDPVTLEYITRFIAQLKQKYTQSNGRRPFGLSTLIIGFDGKPHLYQTDPSGTYFEWTA NAIGRSAKTVREYLEKHYTAEVANNRETQKLALKALLEVVQSGSRNMEVAVMEKDKPLRI LETAELDELIQEIEKEKEEEAEKKKKK--------------------------------- ------------------------------------------------------------ -----PMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDQLEPGCSVLLNHKVHAVV GVLSDDTDPMVTVMKLEKAPQETYADIGGLDQQIQEIKESVELPLTHPEYYEEMGIKPPK GVILYGAPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPS IVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSKGDVKVIMATNRIETLDPA LIRPGRIDRKIEFPLPDEKTKRRIFAIHTNRMTLADDVSLEDYVMAKDDLSGADIKAICT EAGLLALRERRMKVTNEDFKKAKENVLYRKNEGTPDGLYLXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXDNFYLRYYVGHKGKFGHEFLEFEFRPNGKLRYA NNSNYKNDTMIRKEAYAHKSVMLELKRIIEDSEVMEEDDALWPPPDRVGRQELEIVIGDQ HISFTTSKIGSLVDVNQSKDPEGLRTFYYLVQDLKCLVFSLIGLHFKINPIMAIQKKTKK AIESINSRLALVMKSGKYQLGYRQTLKSLRHGKAKLVIIANNTPPLRKSEIEYYAMLAKT GVHHYTGNNIELGTACGKYFRVTTMTITDPGDSDIIRSLP--XXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXX---RYNIHSQLEHLQSKYIGTGHADTTKWEWL TNQHRDSCASYLGHFDMVNYFAIAENETKARVRFNCMERMLQPCGPPPERAEDMKIELCV FSGCKIYPGHGKKQVKVDGKTFHFVNSKCAKLHNAKLNPRKLNWTVLYRRKHKKGMQEEV QKKRTRRAVKFQRAITGATLNDILAKRNQKPEVRQAQREQAIRAAKEKAKAKDKSQPRVG GKRMKLNISYPATGCQKLIEFEDEKKLRAFYEKRMAQEVSAESLGDEWKGYIVRISGGND KQGFPMKQGILTNGRVRLLLSAGHSCYRARRDGERRRKSVRGCIVDANLSVLNLVIIKKG EQEIPGLTDTTVPRRLGPKRASKIRKLFNLKKEDDVRQYVVRRPLAAASKAPKIQRLVTP LVLQRKRHRLAMKRRRATKKREEAAEYQKLLAQRLKEAKERKLERRRSASHSKKVKAKDL RGKKKDDLVKQLDDLKTELSQLRVAKVTGGAASKLSKIRTVRKSIARVLTVINQTQKDNL RKFYKPKDLRPKKTRALRRALTKHELGIRSAKTMHRERTFPMRKYAVKEEPKGPKVTDKV YFDIEIGGEKTGRIVIGLFGKTVPKTVKNFKTIAEGTQTYKGSKFHRVIKDFMIQGGDFT RGDGTGGRSIYFADENFKLKHYGAGWLSMANAGKDTNGSQFFITTAKTEWLDGRHVVFGV VLEGMDIVRGIEQSPKDRDRPRKDVVIADCGSIPVETPFAVAKKPSPEKKKKPSQKFTVD CTHPVEDGIMDPANFETFLQQRIKVNGKTGQLKSKLIVTSEIQFSKRYLKYLTKKYLKKN NLRDWLRVVASSKDAYELRYFQINNEEEDEDEDKMADDKADEENKFGGCEGPDAMFVKLV SSDGHEFIIKREHALTSGTIKAMLSGPGQFAENETNEINFREIPSHVLQKVCMYFTYKVR YTNSSTEIPEFPIAPEIALELLMAANFLDCEKTYTLAELRQHKDVKSLWLAVHDDVLDIT KFLEEHPGGEEVLLEQAGGYATDAFEDVGHSTDARELMKKYVIGKLAPADRGSWMTWLVP LALAVGATLLYRYFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----QLEFLQVQEDYIKDEQKNL KKEYLHAQEEVKRIQSVPLVIGQFLEAVDQNNGIVGSTTGSNYYVRILSTIDRELLKPSA SVALHKHSNALVDVLPPEADSSITMLSADEKPDVAYSDIGGMDIQKQEVREAVELPLTHF ELYKQIGIDPPRGVLMFGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVR DVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTVNVK-- ------------------------------------------------------------ --------------------------------------------------SHAPLTLDML KDRVLLVLRLYDKIDPEKLTLDSHFSNDLGLDSLDHVEVIMAMEDEFGFEIPDADAERLL RPADIVQYVADKEDVRRVVQTMSDDLKNVEFETSEEVEVTPTFDALGLREDLVRGIYAYG FEKPSAIQQRSVKPIVKGRDVIAQAQSGTGKTATFSIAVLQSLDTQVRETQALILSPTRE LAQQIQKVILALGDYMSVQCHACIGGTNIGEDIRKLDYGQHVVSGTPGRVFDMIRRRNLR TRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQ------------------------ -----------------------------------------------NTKRKVDWLTEKM REANFTVSSMHGDMPQKEREAIMKEFRSGASRVLITTDVWARGIDVQQVSLVINYDLPNN RELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLIVPVRRP FDPVAYELDPNFRLTKFSDLKGGCKVPRDGLNKLLDPLREQLEAEQMHFQYVMPTPRIGI GMDACITPIRHGGLSLVQSTSFFYVLVDDPYMMGKVACSAVLSNLYAMGVTECDNMLMHV GVAQKMTDKERAAVLPLLSTGFKDAAEDAGTTVNGGQTVLNPWMVIGGVATSVCQPNEYI MPDNAMVGDVLVLTKPLGTQVAVTAYGWLDVHEKWNRIKLVVGEEDVRKAYQRAMFSMAR LNRIASLLMHKYNAHGATDIGGYGLLGHANTLAGIQKNEVGFVIHNLPVIAKMAAVSKAC GNMFGLLQGHGAETSGGLLIALPRE----FCKDIEKQEGYQAWIIGIVEKGTRTARIIDK PRVIEVPAKDKEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXX------------------------------------------------------- ------------------------------------------------------------ ---------------------------------YYETSAKEAVNVEQAFQAVARQALAQE TEADTYNDFPEQIRLSADTPSSQCSCTAPFDSRFPNQNQTRNCWQNYVDFHRCTKIENYA PCEYFKKYFTTICPNEWITLWDGQREKGAFAGKIMPDYLGSDQRKTTDKNEDDKPIQSLD EGDIALLKTYGLGMYHRAIKAVEEDTKNVLKRVNELSGIKESDTGLALPAHWDLAADRQT IHQEEPLQVARCTKIINAGRDDAKYMINVKQFAKFVVELGDQVAPSDIEEGMRVGVDRMK YKIQIPLPPKIDPTVTMMQVEEKPDVTYADVGGCKEQIEKLREVVETPLLHPEKFVNLGI DPPKGVLLFGPPGTGXTLCARAVANRTDACFIRVIGSEL--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------XEKDFLEAVNKVIKAYAKFSATPRYMTYNMGAEKVHINIVVI GHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITI DISLWKFETAKYYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQT REHALLAFTLGVKQLIVGVNKMDSTEPPYSEARYNEIQKEVSAYIKKIGYNPDYVPFVPI SGWNGDNMLKMTWFKGWKVYTGVTILESLDNIDQPKRPTDKPLRLPLQDVYKIGGIGTVP VGRVETGTIKAGMVVTFAPVNLTTEVKSVEMHHTALEEAYPGDNVGFNVKNVSVKDIRRG NVAGDSKNDPPKETEEFKAQVIILNHPGQINAGYAPVVDCHTSHIACKFRDLLEKIDRRS GKKLEDNPANVKSGDAAIVEMVPQKPMCVEAFADYAPLGRFAVRDMRQTVAVGVIKSVKK RDGGQGKVTKAAVKAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXX--RGTIELGDVTGHNIKQLRRLNEVVFPVVYNDKFYKDIL EVGELAKFAYFNDIVVGAVCCREDHSDGQRRLYIMTLGCLAPYRRLGIGTVMLEHVLRLC EQDGGYDNIYLHVQISNTVAIEFYKKFGFDIVDTKENYYKHISPADAYVLQRTFQ-MPKQ IMEIKDFLLTARRTDAKSVKIKKNVKFKVRCSRFLYTLVINDKEKAEKLRQSLPPGLQVK ELKMSKVSRDSLMEAVNAMLQKERKFTETVELQIALKNYDPQKDKRFSGTVKLRHIPRPQ MSLCVLGDQQHCDEAKANSVECMDVEGLKKLNKNKKLIKKLAKKYDAFLASDSLIKQIPR IVGPGLNKAGKFPTMLTHNESMMGKIDEVKATIKFQMKKVLCLAVAVGHVKMSPEELAAN INLAINFLVSLLKKNWQNVRSLYIKSTMGPAQRLYMADADKLNIDSIIARLLEVRGSRPG KNVQLSENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES SYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKETMGWGENDRGVSFT--------------------------------------- -------------------------CSFQILKPADKKKFLQGNPT-GRPVTPLRGAAKNA GKMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXMTDPVIQNLQDPFAEDE-IHIRIQQRNGRKTLTTVQGVSSEFDLKKI VKVAKKEFACNGTVVEHPEYGEVIQLQGDQRQNISKFLKQVGLDDQIKVHGFXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXTGRIASFAIRQLPKTFSEKQALGAGFVACRKLNTSAEISSILEDRILGSTSANLEET GRVLSIGDGIARVYGLKNIQAEEMVEFSSGLKGMALNLEPDNVGIVVFGNDKLIKEGDIV KRTGAIVDVPVGLELLGRVVDALGNPIDGKGPIN-AKRARVGVKAPGIIPRISVREPMQT GIKAVDSLVPIGRGQRELIIGDRQTGKTAVAIDTIINQKRFNDGQNEKAKLYCIYVAIGQ KRSTVAQIVKRLTDSDAMKYTIVVCATASDAAPLQYLAPYSGCAMGEFFRDNGRHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDSFGGGSLTALPIIE TQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQMRAMKQVAG SMKLELAQYREVAAFAQFGSDLDAATQQLLSRGVRLTELLKQGQYAPMAVEEQVAVIFAG VRGFLDKVDPSRITAFEREFLAHIRSSQQELLKTIREAGKLTDETEAQLRKVVTEFLAGF MESLYALPFAVLECPNLKLKKPSWIHMPSAMFVFALVLLSYFLVCGGIIYDVIVEPPSIG STTDERGNSRPVAFMQYRVNGQYIMEGLASSFLFTMGGLGFVILDQTNKPTTPRLNRILL LAVAFVCIIVSFFMCRLFMRMKLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEYAQVTKMLGNG RLEATCFDGTKRLCHIRGKLRKKVWINGGDIILVGLRDYQDGKADVILKYSADEARNLKA YGELPESAKINEDGDDNVYFDDIDEMLVRFLMKLSHETVTIELKNGTQVHGTITGVDVSM NTHLKSVKMTVKNKDPIQLETLTIRGNNLRYFILPDSLPLDTLLIDDAPKARGRGSSVAK PKGEMTPEELAQKEQEEFNTGPLSVLTQSVKNNTQVLINCRNNKKLLGRVKAFDRHCNMV LENVKEMWTEVPKTGKGKKKSKPVNKDRYISKMFLRGDSVILVLRNPLPIIIDARGHLLG RLAAIVAKTTLQGQRVVVVRCEGINISGNFYRNKQKYLDFLRKRMNTNPCRGPYHFRAPS KIFWRTVRGMLPHKLARGKEALERLKVYEGIPPPYDKMKRQVVPSALRVLRLKPRRKYCQ LSRLSHEVGWKYQTVVATLEKRRKLKSSVYYKRKVADRKLLEKAKKMDKYQKVIEAYGYQ GDPEKGRKVFVQRCSQCHTIDAGGKHKTGPNLYGLIGKQCGQAPGYIYTEANKSKGITWT REKLFEYLQDPKKYIPGTKMVFAGMKKETERADLIAFMEQASK----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------DAQYLQQTVGDCLIHCLAEVCQKQPADPIEYIAHWL-----------MFEAR LVQGSLFKKVLEAIKDLLNEATWDCNSTGMSLQAMDSSHVSLVSLSLRSDGFDTYRCDRN ISMGINLASMSKILKCAGNDDAITVKASDNADTITFMFESPNGEKVSDYEMKLMDLDTEH LGIPETDYSCVIKLPAAEFQRICRDLSQIGESVVICCTKEGVKFSASGDLGTGNIKLAQS ANVDKEEEAVTIEMQEPVVLTFALRYLNFFTKATPLSPQVCLSMSADVPLVVEYKIGDMG FIRYYLAPKIEDGEDA-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------EVSALLGRIPSAVG YQPTLATDMGTMQERITTTQKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIA ELGIYPAVDPLDSTSRILDPNIVGQEHYEVARGVQKILQDYKSLQDIIAILGMDELSEDD KLTVARARKIQRFLSQPFQVAEVFTGTEGKLVPLKDTIRGFKMILNGEMDHLPEIAFYMV GPIEEVVKKAERLAEERMLMPTKNRQLIYEYLFKEGVLVAKKDFQAPKHPDIEVPNLHVI KTLQSLKSRGYVKEQFAWRHYYWYLTNEGIQFLRDALHLPPEIVPATLKRQAMGEDRAAY RREGGFDKKGEAGAGATXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXMSSSEEVSWISWFCGLRGNEYFCEVDEDYIQDKFNL TGLSEQVPHYRQAIDMILDLEPDDELEDNPNQSDLIEQAAEMLYGLIHARYIMTNRGIAQ MIEKWQQGEFGNCPRVYCDNQPSLPVGLSDVPGEAMVKLYCPKCQDVYVPKSSRHHHTDG AYFGTGFPHMLFMVHPEYRPKRPANQFISRLYGFKIHPLAYELQYQSAASFKAAYMNSKR MTNSKGYRRGTRHMFQRDFRKNGVIPLSTYMKVYKRGDRVDIKGNGAIQKGMPHKVYHGR TGIVYNVTPHAVGVIVNKRVKGRILAKRINVRVEHVKHSRCRQDFLDRVAENERKKREAK QIIHCKRQPAQPHPEHFVRTKYNKPIVLEPIPYEFIAAPRMHWKQVSPADKSMDWKDITD RAANTAFFIELFKGLGIVMSHLFKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAICPAQAITIEAEERADGSRRTTRYDIDMTKCIFCGFCQEACPVDAIVEGPNFEY STETREELFYNKEKLLDNGDRWELEISANLQADYLYRMATPNKVAKRDAKNNHGGDKDQQ DAIERIDEVQNEIDRLNEQASEEILKVEQKYNKMRQPHFQRRTDLISKIPNFWVTAFVNH PQVSALLSEEDEEALQYLKKVEVQEFEDIKSGYKINFYFDENPYFENKCITKEFHLNSSK STPINWKPGKDLTKSKHKRSHSDQESFFGWFLDHNDAGADELGEVIKDDIWPNPLQYYLA SEIEEEGGGEEGAEDEDKKLTKQEELLLQDFSRNVTTKSSALFYGNAFIVSAIPVWLFWR IYQMDLYLLFVVMTLITAYFVAMAYKNVKFILKHKVALKRGDAVSREVMKKFADDKKMSK QEKEERILWKKNEVADYEATTFSIFYNNALFLTLIIITSFYILRTLSPPINYTLSMASAG GLLALFSTSSKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXMAEYLASIFGTEKDKVNCSFFFKIGACRHGERCSRLHNKPTFSQTILMQN LYLNPQNSAQLGVTDTEMQEHYDEFFEEVFSELEDRYGRIEEMNVCDNLGDHLVGNVYVK FEREEDAEKAVTELNNRWFNGRPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKP ISRELRRRLYGRSKRSRSRSPPTRRSRSRER---KFRERSRERA-MFLARSEYDRGVXTF SPEGRLFQVEYAIEAIKLGSTAIGIQTAEGVILAVEKRVTSPLIVPSSIEKIMEIDTHIG CAMSGLIADSKTLIDRARLEAQNHWFTYNQRMRVESVTQAVSNLALQFGDDDADPAAMSR PFGVALLFAGIDENGPQLFHMDPSGTFLQYDAKAIGSGSEGAQQSLNEIYNKSMKLETAC IEALKILKQVMEEKLTSTNIEMAIVTPGKLFHMLTKDEMEALM---XXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX-----RMKRELAMFADSPPFGISCWSKDSSLEHLEAQIVGGDCTPYKGGIFKLEITI PERYPFEPPKVQFLTPIYHPNIDSAGRICLDSLKGAWRPALNMCTLLTTIQLLMAEPNPD DPLMTDIANEFKYNRPQYEMKAKDWTQQHAENTDELLDYEEEEQEDVKDVKGTYVSIHSS GFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVVCQAKSGMGKTAVFVLATLQ QLEPVAGQVSVLVMCHTRELAFQISKEYERFSKYMNSVKIAVFFGGMLIQKDEQTLKTNC PHIVVGTPGRILALVKVLNLKHLKHFVLDECDKMLEQLDMRRDIQEIFRATPHEKQVMMF SATLSKDVRPVCKKFMQDPMEVYVDDDSKLTLHGLQQHYVKLKDNEKNRKLFELLDALEF NQVIIFVKSIQRCMALAQLLVEQNFPAIAIHKAMTQDERLSRYQQFKDFQKRILVATNLF GRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDETDAKVPPTFADLG KSSRDLFNKGYNYGVYKVEAKTKTTNGIEFTVNGSSNHDTKKFVGNLETKYKWSEYGITF NEKWNTDNTIGTEVTVEDQLLKGLKLSFDTQFVPQTGKKGGKIKTEYKHDYFRTNLDVDF NFAGPTIFGAVVFGYRGWLAGYQAALDKSLLSQSNFAIGYTKDDLTLHTAIKDNQEFSGS VYHKVNSRLETGVQVDWTVGSNDTRFGLGAKYCPDRDTTLRAKLNNSSQIALSYQQKLRD GVTLTLSSLLEGKNFANGGHKFGLGVDFE------------------------------- ------------------------------------------------------------ ----TRVALDMTTLTIMRYLPREVDPLVYNMSTEDPGDISYAQIGGLSEQIRELREVIEL PLMNPELFQRVGITPPKGCLLYGPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIGES ARLIREMFSYARDHQPCIIFMDEIDAIRRFSEGTSADREIQRTLMELLNQMDGFDALGQV KMIMATNRPDTLDPALLRPGRLDRKIEIPLPNEQARMEIIKIHAAPIAKHGEIDWEAVVK LSDDFNGADLRNVCTEAGMFAIRAERDFVIEEDFLKGVRKIADNKKLESKLDYKPLMPES LGSVVKRFADDYIQFTPRKLKIIDAYLVFILLTGIVQFVYCCLVGTFPFNSFLSGFISCV GSFVLAVCLRVQVNPQNKTEFIGIGAERAFADFIFAHVILHLVVINFIGXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX----VVGDLHIPHRANAVPAKFRKLLVPGKIQHILCTGNLCTKES VDYLKTLASDVHIVRGDFDENLTYPEQKVVSVGQFRIGLCHGHQVVPWGDTESLAMVQRQ LDVDILISGHTHKFDAFEHEGKFYINPGSITGAYSALDSNIIPSFVLLDIQQSTMIAYVY QLFGADVKVERIEYKKMGKFMKTGKVVLVLGGRFAGKKAIIVKNYDDGTSDKQYSHALVA GIDRQPRPITRKMGKKKMKQRSKVKAFVKVYNYNHLMPTRYSVVNLDKQLVNKDAFRDPA LRRKARREVKAKFEERYKTGKNRWFFQKLRFERTFIMVKPDGVHRGVVGEIIKRFEQKGY RLVAMKMEWASEEQLKKHYDELKERPFFPKLVKYMSSGPVVPMVWEGKVVDTGRVMLGAT DPLKSNPGTIRGDFGIDVGRNICHGSDSVASAEREIALWFKENELVAWIPAAVDWIYEPA VPKPVKTQAKNKDKALKAKKAVLRGVHEKRSRKVRTAVHFRRPQTLRLPRAPKYPRKSTP KRVRLDQFKIIKFPLTTESAMKKIEDNNTLVFIVDKRANKPQIKMAVSKLYSIQVSKVNT LIRPDGEKKAYVRLQPDYDALDVANKIGIIMAPKQKMRLANEKHSKDVLCRGNVPKSLKQ EEEKLPVGPWLLGLFIFVVCGSAVFQLIQSIRMVKFKELTAVGVWRWVANDDSCGICRMP FDGCCPDCKLPGDDCPLVWGQCSHCFHIHCIVKWLNSQQVNQLCPMCRQEWKFKEXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXGDTIFGKIVRGEIPTKFIHEDDQCVAFHDISPQAPIHFLVIPR RPIQMLSSDELLLGHLLVVARRVASKESGYRVVINNGRDGGQAVYHLHVHVLAGRQLGWP PXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX X----------------------------------------------------------- -------------------------------TAWFGGGTLRVHLSIHVGERANDYQEIAA KDKLSELQLRVRQLLDQVDQISKEQNYQRYREERFRETSESTNQRVLWWAIAQTLLLVVT GFWQIRHLRGFFEAKXLVMFFHVSLTHDILLHPRYFGPNLLNTVKQKLFTEVEGTCTGKY GFVIAVTTIDNIGAGLIQPGRGFVVYPVRYKAIVFRPFKGEILDAVVTQVNKVGLFTEIG PLACFISRHSIPADMEFDPNSNPPCYKTRDEDIVIQTEDEIRVKIVGTRVDATDIFAIGT LMDDFLGLVSRLYVKAVFTGFKRGLRNQHENTALLKIEGVHAKLETDFYLGKRCCYVYKA KNKTACPGHEKPSHLRVIWGKITRPHGNSGAVRAKFHKNLPPKAMGRRIRVMLYXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPQNEYIELHQKR HGRRLDYEERKRKRESRLPHELSQKAKKLRGIRAKLYNKKRHAEKIQMKKTIKMHEERKT RQKAPESRLDGPVPKYILDREEQTRAKVLSNTIKQKRKEKAGKWEVPLPKVRGVSEAEVF KVVRTGKSRRKAWKRMVTKVCYTGEAFTRKPPKYERFIRPMALRFKKAHVTHPDLKATFC LPIIGVKKNPTSPLYTSLGVITKGTVIEVNVSELGLVTQGGKVVWGKYAQVTNNPENDGC INAVLLV-AARPLVSVYDEKGEPTGRNVSTPSVMLAPIRPDIVSFVHMEMLKNGRQPYAV SEKAGHQTSAESWGTGRAVARIPRVSGGGTNRSGQGAFGNMCRGGRMFAPTKTWRRWQRH INVTQRRYAICSALAASAVPALIMSKGHRIEQIPEVPLVLTDKIQELKKTKEAVTVLRKL KAWPDIEKVKNSRRFRAGVGKMRNRRRIHRRGPIIIYAQDNGICRAFRNIPGITLINVDR LNLLKIAPGGHVGRFCIWTESAFKKLDGIYGSWSKVSKEKSNYTLPMPKMTNTDLSRLLR SDEIQKALRAPKKENPKRVLKRNPLKNLAVMQRLNPYAVTQKKNAKQKEIRQAKIDARRG IITVDSGGKARPRKTGK-SEEEELASKSLQIQSKRFYLDVKQNKRGRFIKIAEVGAGGRK SRLLLAMSTAAEFRDHLTDFSEYYVSLGPANPDAPPEDGKLKSATMTKENRHYYLDMKEN QRGRFLRVSSTSMQRAQIVIPAQGMIEIRDALTDLLKEFGTDDQDGLDGLPDAQSMRVEN KMFYFDVGQNRRGVFMRISEPNYRTAVTIPEQYWARFRDVLSTFVDRADERNRDAQLRTM INQKLIETGERERLKELLRTRLIECGWRDELKQYCKEIVRQKGLENITVDDLVAEITPKG RALVPDQVKKELLQRIRTFIAQQSNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXX--------QPGKKPEGRTYSDYESVNECLEGTCKIFEEYLKKMNPNSPSITYDISQ LFEFIDQLADLSCLVFDKASGKYVPHNKAWIKEKIYMLLRQQAGKXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSHRKFSAPRHGSLGFLPKKRSRHQRGKV KAFPKDDKSKPVHLTAFLGYKAGMTHVVREVDRPGSKVHKKEVVEAVTILEAPPMVIVGV VGYIDTPRGPRSLKTIWAEHLSDECRRRFYKNWYRSKKKAFTKAALKWQDETGKKEIEKD FAKLKRYCTIIRVIAHTQMKLMKRRQKKAHIMEIQLNGGTIAEKVDWAREHMEKAVPISK VFGVDEMVDVIGVTKGKGFKGVTSRWGTRKLQRKTHKGLRKVACIGAWHPSRVSFSVARA GQKGYHHRTEMNKKIYRIGEGEHAEGGKVIKNNASTDYDTTEKMITPMGGFAHYGQVKQD YIMLRGCCMGPKKRVITLRKSLLPQTSRRALEKVDLKFIDTSSKFGHGRFQTHEEKHTFM GPLKKD------------------------------------------------------ ------------------------------------------------------------ TKLDLREDKETIDRLRDKKLSPITYPQGLAMAKEIGAVKYLECSALTQKGLKTVFDEAIR AVLCPKPKPKKKKQCRLLIFDPSLKKKKKKKTSFDPDAF-KEIALDD-ALTKKKKKKKAF DMADVDAALPSTEETTSKKKKKEDSDRDYTYDELLKRVFDTMRLKNPDMVAGEKKKFVMK PPQVMRVGTKKSSFSNFAEICKMLHRQPKHLLDFLLAELGTNGSIDGNNQLIIKGRFQQK QIESVLRRYIKEYVTCHTCRSPETILQKDTRLYFLQCETCGSRCSVASIKSGFQAVTGKR AAIRAKTTFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDITRPEGK DYSLHRLILGTHTSDEQNHLLIASIQLPKDTAQFDVSHHDTEKGEFGGFGSVSGKIEIEI KINHEGEVNRARYMPQNPCVIATKTPSSDVLVFDYTKHPSKPDPSGECRPDLRLXGHQKE GYGLSWNPNVNGHLLSASDDHTICLWDINTTPKEGRVINAMTIFTGHTS----------- ------------------------------------------------------------ ------------------------------------------LHVWDLSKIGEDQSAEDA EDGPPELLFIHGGHTAKISDFSWNQNEPWVICSVSEDNIMQVWQMAENIYNDEEPEAANT ELEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPVPETLLKKKKQKGLKNHDKKLEIFKRAE KYAREYAIKDKSEIQMARQARKHGNYYVPPAAKLAFVMRIRGINGLHPKPRKVLQLFRLR QINNGVFVRLNKATINMLRLAEPYITWGYPNLKSVRELVYKRGYAKIRGCRIPITDNSII ESKLGKFGIICVEDLIHEIYTVGPYFKQATNFLWYFKLNTPNGGWRKKTNHFVDGGDFGC REDKINVLLRKM-----------KLRLQKWYVAHPDKTKKKITRELITMILSRKPKMCSF LEWKDLKIVYKRYASLYFCCCIEPGDNELLTLEVIHRYVELLDKYFGSVCELDIIFNFEK AYFMLDELLLGGEVQESSKKNVLKAIAAQDLLQEETPQGFFEDHGLGMSKAHPPELKKYM DKKLQLRLNGGRTVTGVLRGFDPFMNLVIDEAIEECKTGEKNSVGMVVIRGNSVGLLEAL ERIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXMAIIYDMAIGLKKGHKVTTKKPRPSQRKGTLTKHAKFVRDLIR EVSGFAPYEKRAMELLKISKDKRALKFCKKKLGTHLRGKRKREEMAHTLQQQRKA----- ------------------------------------------------------------ ------------------------------------LDGKTAKMYRGGKICMTDHFKPLW ARNVPKFGIGHAMALGLGPWLAVEIPDLVSKGIIQHKEXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX- -------------------------------------HELQAQKEKIKENTEKIKVNKTL PYLVSNVIELLDVDPQDQAEEEGANVDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEQL KPADLVGVNKDSYLILETLPQEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELIEAVVLP MTHKDRFKALGIQPPKGVLLYGPPGTGKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGA KLVRDAFSLAKEKAPAIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNHD IKVIAATNRVDILDPALLRSGRLDRKIEFPAPNEEARARIMQIHSRKMNVSKDVNFEELA RCTDDFNGAQCKAVCVEAGMIALRRNATELSHEDYMDAILEVQAKKKANLNYYAXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXX------------------IELAEKEMPGLMMMRKVYGASKPL TGAHIGGCLHMTVQTAVLIETLLELGAEVQWSSCNIFSTQDHAAAAIAKRGVAVYAWKGE TDEEYIWCIEQTLIFPNGKPLNMILDDGGDLTNLVHEKYPEYFEEIKGISEETTTGVHNL YKMLQKGELKAPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDIMLAGKVALVAGYGDV GKGCASSLRGFGTRVLVTEIDPINALQAAMEGYEVTTIEEAVKEARIFVTATGCKSIISG PNFMEMLDDSIVCNIGHFDCEIDVKWLNENCVSKVSIKPQVDRYTLKNGRHIILLAEGRL VNLGCAMGHPSFVMSNSFTNQCLAQIELWTKTDKYPLGVHFLPKTLDEEVARLHLDHLGV KLTKLTPEQASYLGVAVTGPFKPDHYRYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSRSISDIVRNSPF AGPFGLKVNENRTVSALAETYSCEYASNKFYALCAFGGIISCGTTHTAVVPLDLVKCRIQ VDSAKYGNIIKGFRVTLKDSGFRELGKGWAPTFFGYSAQGMFKFGLYEVFKHFYADLLGE ETSYLWRTSLYLAASASAEFFADIALCPMEAVKVRIQTQPGFARTLREGAPKIFRDEGMW GFYKGIVPLWGRQIPYTMMKFACFERTVEAIYKYVVPKPRSQCTKAEQLVVTFCAGYIAG VFCAIVSHPADTIVSKLNQQKGSSFMKIGMSLGFWGMWKGLFPRIIMIGTLTALQWFIYD SVKVYFRLPRPPPPEMPESLKAKLAHWTNERYVAIALLPIIPAAIAYVLDTLLSAMVLHT HWRLSGVVQDYIHLTISAFGSLCYFNYTDIGFARAVRLLYSSVNEQPEEDASELIFPKEF ENAETLLISEVQRKQQNESAEDEQELSSVFIKTLNYTQRFSKYKNRETISAVRSLLVQKK LHKFELATLANLCPETSEEAKALIPSLEGRFEDDDLQQILDDIKTQRSFQY--------- ------------------------------------------------------------ ------------------------------------------------------------ -------------DAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILIMQNKIDLVKESQ AKEQHDQIIKFVQGTVADGAPIIPISAQLKYNIDAVCEYIVKKIPVPIRDFTSEPRLIVI RSFDVNKPGCEVEDLKGGVAGGSILRGVLKVGQEIEVRPGIVSKDTEGKLTCKPIFSRII SLFAEQNDLEYAVPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPDIFIELEISYFLLR RLLGVRTEGDKKGAKVQKLAKNEVLMVNIGSLSSGGR----------------------- ----------------------------MAELLLDSDIRIWVFLPIVVITFLVGIIRHYV TILLSSDKKVELQQISDSQALIRSRLLRENGRFLPRQSFLMRKHFFNHEETGYFMKNPMT DPSMMTEMMKGNITNVLPMIIIGGWINWAFSGFLTTKVPFPLTLRFKPMLQRGVELASLD ASWVSSASWYFLNVFGLRSMYSLILGQDNAADQSRIMQDQMTGPAMGMPPDPSKAFKAEW EALEICDHKWALEDIDDELFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPN IKLQSSDGEVFDVDVEIAKQSVIIKTMLEDDEGEDEPVPLPNVNAAILKKVIQWCTYHKD DPPAPEDDENKEKRTDDICTWDVEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMI KGKTPEEIRKTFNIKNDFTPAEEEQVRKENEWCEEKNKRLSKGGKKGSKKKATDPFTKKD WYDVKAPSMFNTRNIGKTIVSRTIGTKIASDALKGRVFEVSLADLQNDEVAFRKFKLVSE EVQGRNVLTNFHGMDMTTDKLRSMVKKWQTMIEAHVDVKTTDGYLLRLFCIGFTMRRQNQ VKKTAYAQTTQIRAIRRKMVEVMSREVSSNDLKEVVNKLIPDSIGKDIEKICQSIYPLHD VYIRKVKILKKPKFDLGKLLEMHGEGTTTKPGEVGESVTRPDNYEPPVLAAVXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------PHCVPISAHHKWNFDDLLEKMWQYLMLVRLYTKPKGQLPDYNAP VVLKLDHRSVEDFCNKLHRSIIREFKHALVWGSSVKHQPQKVGKDHVLSDEDVIQIAKKM AKHHPDLIFCRKQPGVAIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGSYQGRCVIC GGPGVSDAYYCKECTITEKDRDGCPKIVNLGSAKTDLFYERKKYGFKKR----------- ---------------------------------------------------------IGA LQRAADFVRAFTLGFEVEDALALLRLDHLYLESFDITDVKPLKGDHLSRAIGRLAGHHGK TKFTIENVTQTRIVLANSKVHILGSFNNIRVARTAICNLILGSPASKVNGKLRTVAARAA EK---------------------------------------------------------- ------------------------------------------------------------ ------------HAHGDQYKATDYVVKEPGKLEMVFTPKGGKETRMEVFTFKDKGGVGLA MYNTDESITGFAHSCFQFAIKKKWPLYMSTKNTILKRYDGRFKDIFQEIYEEKYRKEYEA AGIWYEHRLIDDMVAQALKSNGGFVWACKNYDGDVQSDVVAQGYGSLGLMQSILMCPDGK TIEAEAAHGTVTRHYREFQKGRPTSTNPVASIFAWTKGLEHRAFLDNNPDLARYCQVMEK ACVDTIDAGXMXQDLAACIYGLKNVKENQYLNTSDFLD-------XXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFGDLKTAAGLKALNDYLGDR SYIEGYIPSEADASVFEAVGSPSTDFVHVVRWYKHIDSFGAGRKSFPGAQSPAPVT---- -AAGGDDDDFELFGSAAEKLKQERLAAYAAKKSTALVAKSSLVLDVKPWDDETDMAKVEE CVRSIEADGLLWGASKLVPLAYGIKKLQISCVVEDDKIGTDFLEEEITKFEELVQSVDIA AFNKI---------RIERIGAHSHIRGLGLDDGLEARQVSQGMVGQTSARRAAGIIMEVI KEGKIAGRAILIAGHPGTGKTAIAMGMAQALGTDTPFTAIAGSEIFSLEMSKTEALTQAF RKSIGVRIKEETEIIEGEVVEIQIDRPATGTGAKVGKITLKTTEMETIYDLGQKMIESLT KEKVQAGDIITIDKATGKISKLGRSFTRARDYDAMAANTRFVQCPEGELQKRKEVVHTVT LHEIDVINSRTQGFLALFS----------------------------------------- ----------------------------------TQYLSPHGIPIDLLDRLLIISTKPYD DKEIGQILKIRCEEEDVEMSDDALTVLTRIGKETSLRYSIQLIATASHVCRRRKGTEVSV DDVKRVYSLFLDESRSTQFLKEYQQEFMFYEMASYDLITRMGQYLDRHLVFPLLEFLSVR QIYDESEMLKGKLDLLSNTNMVDFAMDVYRNLYPDKEVPQSLKDKRQSVVAELKRLTAET ESITKIFEDEEISIQNTRDGRQLYEYLTKNFDFKMEMLDTLYRFAKFQFECGNYSGSAEY LYIVRVLMPPTDRHYMNVLWGKLASEILMQDWDTALDDLTRLREVLDSPLILLQQRTWLI HWSLFVFFNHPKGRDLIIDMFLYTP--------------------------LLKDLVKVI QQESYTYRDPITEFLECLYVNFDFDGAQQKLRECETVLINDFFLVACLDDFIENARLFIF ETFCRIHQCISISMLADKLNMAPEEAERWIVNLIRNARLDAKIDSKLGRVVMGTQAVSPY QQVIEKTKNLAFRSQMLVMNIEKKLATKDMGVDVETIKPGDGVTFPKSGQKVIVHYTGTL TNGKKFDSSKDRGKPFEFNIGKGQVIRGWDEGVAKMSKGQTAKLTCSPDYAYGDKGAAGV IPPNATLIFEVELLDIKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXLCCLVSVAFCD--VFFQEEFWRNRWVESTHKGGEQ GAFGWTAGKFYGDAERDKGLQTTQDARFYAISAKFDKPFSNEGKTLVVQFSVKHEQEIDC GGGYVKVFASDLDQKDMHGDSPYHIMFGPDICGYSTKKVHVIFTYKGKNLLIKKDIRCKD DTLTHLYTLILRPDNTYEVKIDNKKEESGTLEADWDFLAPKTIKDPEAKKPDDWDERENI DDPEDTKPEDWEKPEHIPDPDAKKPEDWDDEMDGEWEPPMIDNPEYKGEWKPKQIPNPAY KGKWVHPEIDNPEYQPDDALYKFTDIGAIGFDLWQVKSGSIFDNVLVTDDEKYADEFAEQ TWGKSKDGEKKMKDDHDEEERKKREEEEKKRKDDDKEKEEDEEEMDNGLPEPSMYIVKAI LILDNDGNRLIAKYYDNTFASAKEQKNLFNKTHRANAEIIMIEGLTCVYRSNVDLFFYVV GSAQENELILVSVLNCLYDSISHMLRKNVEKRALIDNMDGIFLAIDEICDDGIILESDPI AIAQRVAFRSDDIPLGEQTVASVIQSAKEQIKWSLLKMNVFRLVGDLSHLLAIIILLIKI WKTRSCAGLSGKSQIMFAMVFTTRYLDLFTTFVSMYNSTMKIIFILSSYATVYLLYKKFR ATYDSNHDTFRIEFLVVPMAGLAVLVNHEFSLLEILWTFSIYLESVAILPQLFMISKTGE AETITSHYLFALGSYRALYILNWIYRYFNEGFLDLIAVLAGCIQTVLYCDFFYLYITKVW KGKKLTLPA--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------MKPKKTEITDKLRKEINKIVNKYIDQGV AELVPGVLFIDEVHMLDIECFTYLHRALESTIAPIVIFATNRGKCTIRGTDDLVAPHGIP LDLLDRLMIIRTMPYSQEEMQQIIRIRAQTESIQVDDESFTNLAAIGVKTTLRYAVQLLT PASILAHINGKNCIKKEDIDEVNDLFFDAKSSAKILAEQRDKYMQEFEAHEEGDKGIIKL KEPARQRKGRGF-TRTEVEEYESMETTTFGPQRSVEGWILFVTNIHEEAQEEDVRDKFAD YGEIKNLHLNLDRRTGFVKGYALVEFDTFKEAQAAIDNLNGTEIAGQKISVDWTFVQGGS KKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------- ------------------------------------KAHVDYQKVVRETIKHIGYDDSAK GFDYKTCNVLLALEEQSPDIAQGVHLGRAEEDIGAGDQGLMFGYATDETEECMPLTVVLA HKLNAKMAELRRSGVLWWARPDSKTQVTCEYRMQKGACVPLRVHTIVISVQHSEDVSIEQ LRSDLMEHVIKSVVPHQYLDDKTVYHLQPSGKFVIGGPQGDAGLTGRKIIVDTYGGWGAH GGGAFSGKDFSKVDRSAAYAARWVAKSLVHAGLCKRILVQVSYAIGVAEPLSIFVSSYGT GIKTDADLLKIVKANFDLRPGKIVKDLDLKRPIYFKTACYGHFGRPEFTXEQPKKLQFXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMAVYKVVMVRHGESAWNAENRFCGWHDADLADSGVQEAIKGAQRLKENKFAFDVAFT SVLKRAIKTLYLIQDGLDLHWIPVHRHWRLNERMYGALQGLNKSETAAKHGEQQVQIWRR SYDTPPPPVDETSEYFPGTDPKYKFVDTRLIPRTECLKDTVARVLPYWYDVIVPEILKGQ RVLIAAHGNSLRALVKYLDNMTDAEIMALNIPTGIPLVYELDKDLKPVKHYYLATDAEVK AAIDKVAAQGKAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXMGIDIRHNKDRKVHRKEPRSNDIYLRLLVKLYRFLARRTNA KFNKIVLKRLFMSRTNRPPMSIARLCRMMKKTGRDSKMAVVVGTVTDDNRIFEIPKLKVC ALHVTEKARGRILKAGGQILTFDQLALKAPKGQNTVLLQGPRKAREAYRHFGPAPGVPHS HTKPYVRSKGRKFERARGRRASRGYKNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMIIPVRCFTCGKVIGNKWEAYLS LLQADYTEGDALDALGLKRYCCRRMLLSHVDLIEKLLNYAPLEKXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMRAGGTLKEYKVVGRMMPTGKMRQ PPIYQMRIFASDRPQAKSRFWYYSSMLRKVKRTQGEILCCNQVYEKKPLAIKNFGIWLRY DSRSGSHNMYREYRDLTTGAAVTQCYRDMGARHRARPGSIQIMKVQVIPASKVRSKNLHQ FLDSKIKFPLPNRVQRRLHYPRFTTRRPHTTFTAYDQMKLFWKKNQKRPNSPWWIYRPHL PMLTSLCHRATGITMGVVLYAASIAVFVAPGDVTGYVEFIKNLNLSPLILFPAKMICAFP LVYHYINGIRHLTWDAGYGYELKTQYKTGTVIFASLAY-XXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXKSNYTLKYTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTITGH KLGISDVAWSSDSKLLVTASDDKTLKIWDVATGKCLKTLKGHSNYVFCCNFNPQSNLIVS GSFDESVRTGKCLKTLPAHSDPVTAVNFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID ------------------------------DYSKGKCLKTYTGHKNEKYCIFANFSVTGG KWIVSGSEDHLVYIWNFQTKEIVQKLQGHSDVVLCCACHPTENIIASAALENDKTIKLWR SD-MKIFKDLFTGDELFSDSFPSVVYKVKGKDESAIGGNASQGVDIVMNNKKDYMTHIKE YMARVKKYQLFCGLALMKWETPYMYFFKHGLEEEKVXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------- ----------------------ALLAADVNVVLVKKLRENVRSVIDFDEMAAGLNKRRMI QSAVFKELVKLIDPGVKAWQPVKGQNNIIMFVGLQGSGKTTTCTKMAYYYQKKGWKTCLV CADTFRAGAFDQVKQNATKAKIPFYGVDTSGRHKQADSLFEEMLQVSNASPDNIVFVMDA SIGQACEAQARAFKDKVDVASVIITKLDGHAKGGGALSAVTKSPIIFIGTGEHIDDFESF KVQPFVSKL--------------------------------------------------- ---------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMTSKDYYFDSYAHYGIHEEMMKDEVR TLTYRNSMYHNRHLFKDKVVLDVGSGTGILSMFAAKAGAKLVIGIECSGIVEYSEKIVKA NRLDHAVKLVRGKVEEVQLPDGIEKVDIIISEWMGYCLFYESMLKTVLYARDKWLKPGGM IFPDRATLYICAIEDRQYKDEKINWWDNVHGFDMSCIRKVAICEPLVDVVDPKQ------ ------------------------------------------------------------ ---------------------------------------------------------MVR DDRTTWKSKYFEKMIQLMIEYPRCFIVGADNVGSKQMQRIRIALRLLMGKNTMMRKAIRG HLEENPALEKLLPHIKGNVGLVFTKGDLTDVRKVIEGNKVAAPAKAGAIATVEVVVPAQC TVLGPEKTSFFQALAIQTKITKGTIEILNDVRLIKIGDKVGASEATLLNMLNISPFTYGL QIEMVYDNGTVFDIGILDITDDDIRSRFLEGVVNISSISLAINYPTMVSVPHTVINVFKN LLAIAVVTDIDFKEAQTAKE-----KLLAVIGDEDTCTGFLLGGIGELDKNRRPNFFVVE KNTSVSDIEEAFRTFTTRDDIAIVLINQNVAEMIRHIIDRYTATIPALLEIPSKEHPYDA SKDSILRRAKGMFAADDFRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPRAIKKTVGGEKNGGSR LVVARRMPRSFPTEERPRKLRRPFSQHKRYLRASITPGTVLILVAGKHKGKHVVFLKQLA SGLLLVTGPYQLNGCPLRRINQIYVIATKTKLDVSGVKLPERLNDTYFKRKELKKPRHTE GEIFDTKKEVYSVSDERKEDQLAVDKQLLDVVRQHPEKKFMFGYLSSLFSLKSKEYPHTM AFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------VLYAFQEQTTEEIVMLNGFGTVVNALGKRVKPYLPQ ICGTILWRLNNKSAKVRQQAADLISRIAIVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLG SILGALKAIVNVIGMTRMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGAEYVS AREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVC TTV--------------------------------------------------------- ------------------------------------------------------------ --------------------------------------------AQDSLTPGYPRVPNDE KNRYVRYELDYIL----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------QSLHIKSAIPHPL IMGVIRECGGKMHLREAEYEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGIN PFDSQEAKPYKNNPEILAMTNLVSAYQNNDITEFEKILKTNRPTIMEDPFIREHIEDLLR NIRTQVLIKLIKPYTRIHIPFISQELNIDVPEVENLLVSCILDNTVHGRIDQVHQLLELQ AGVARYNAMDKWSAQIASLHDSIINRVAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXX----------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------VVTLMTVFLITYTFHCTWVTSEAYSSPSIVLSARGGDGGRII FDDFREAYYWLRYNTPEDAKVMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMSS PEDKAYEIMRELDVSYVLVIFGGLTGYSSDDINKFLWMVRIGGSTERGQHIKEHDYYTPQ GEFRVDKDGSPILLNCLMYKMCYYRFGAVYTEQGKPTGYDRVRNAEIGNKDFELDVLEEA YTTEHWL--------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQETFSLFDNRGDGKI FAHQVGEVLRAMGQNPTEAEVKKCQEPDRRISFEQFLPILSTISKNREKPVLDDFIEGFR VFDKEQNGFIHSAELRHLLTNLGERLTDEEVNELLQGHEDSQGNVNYEEFVKGVLNG--- ----------------------------NLVQCETLEDLKLHLQSTDYGNFLANEASPLA VATIDDKLKEKLVIEFQHMRNQAVAPLSTFLDYITYSYMIDNIVLLITGTLHQRAISELI PKCHPLGSFEQMEAIHIASTPAELYNAVLVDTPLANYFTDCIYEQDLDEMNIEIIRNMLY RSYLEDFYDFCQTLGDSTAEVMSEALAFEADRRAFIITINSFGTELSRDDRFKLYPRCGK LNPDGLWALSRADDYEQVKAVAEFYGEYRVLFEESGSNPGDKTLEDKFFEHEVKLMKNA- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------VRTMSGHASRVGSLSWNTHMLSSGSRSGAIHQHD VRVFAHHV-GTLANHTQEVCGLQWSDDGHYLASGANDNLLCVWDSSASTPVHTFSQHQAA VKAIAWCPWQSSLLASGGGTADRQIRFWNVSSGDCVQTTETNSQVCSIIWSTHYRELISG HGYSQNQLTLWKYPAMARIADLFGHTSRILALALSPDGTTVASAAADETLRFWKCFDCDK RRKTVNS---------AAVVLSFYFTIGQQSHRYGISWLLGETSPFMWANIGIGLGISLS VVGAAWGILKTGSSIIGGGVKAPRIRTKNLVSIIFCEAVAIYGIIMAIVISNSMNQYAGF AMFGAGMTVGWSNLFCGVCVGIVGSGAALADAQNSSLFVKILIVEIFGSAIGLFGVIVSI LQVTHAHMGNKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGASQTFPQQCSALRKNGFVVLKGKACK IVDMSTSKTGKHGHAKVHLVGLDIFTGKKYEDICPSTHNMQVPNVSRTEYEVLDLSEGFF SLMTDDGTTRDDLKLTGTVWKALGDEVVKELKSGK------------------------- ---------------------------------TGLVLVADSNSNCVQVFSTGEFKQKIG RKGHLPGCLLRPTGVAVTQSGNYLVADYESCSINIFTPEGRYLTR--LSGPRLIG----- ------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXKVEPKKVVNPLFEKRPKNFGIGQDIQPKRDLSRFVRWPKY IRLQRQLAILKQRLKVPPPINQFTQALDRQTATQLFKLMDKYRPESRQEKAARLRGRAEE RVKGKPDAATKRPPVIRSGINTVTCLIEKKKAQLVVIAHDVDPIEIVLFLPALCRKMGVP YCIVLGQVVHRKTATCLAFTTVNPEDKAQLTKLTEAVKTNFNDRADEIRKHWGGGQMGAK SKARIAKLEKAKARELAQKMRYVAAYLLAVLGGNDKPSEADIKKILSSVGIEADAACLKK VIGELHGKDLNEVMTAGRSKLAAMPVASAGAAEPKKEEKEEDEDMGFGLFDMPITKIHAR QIFDSRGNPTVEVDLYTEQGMFRSAVPSGASTGIYEALEMRDKD-KAYLGKSVFKAVANV NDVIAPALVLDVTNQAAVDKIMLDLDGTENKSKLGANAILGVSLAVCQAGAAKKGVPLYR HIADLAGNKDLILPVPAFNVINGGSHAGNKLAMQEFMLLPTGASSFSEAMKMGSETYHRL KEVIKAKYGQDACNVGDEGGFAPNIQNNEEGLELLKTAIEKAGYTGKIEIGMDVAASEFC KKYDLDFKNPKSDPATYLTSDQLFEVYKGFISKYPVVSIEDAFDQDDWDAWTKMNAIQLV GDDLTVTNPKRVKMAIDKKACNCLLLKVNQIGSVTESIEACKMSQAAGWGVMVSHRSGET EDTFIADLVVGLCTGEIKTGAPCRSERLAKYNQLLRIEEKLGANAKYAGKNFRNPXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXMNAPPTFESFLLFEGEKKVVIEKDTKVPCAAIFTVNKEDHTLG NALRTQLLKDPQVLFAGYKIPHPLEAKFVLRIQTTPDYSPQEAFTNAITDLISEVSLLEE RFREAIKEKQE--EDHRRKWDRDEFEKLARERLAAEEAKREPAVKRELLKPREYKVDLDS KLGKTQVITKTTPSAQLGGYYCNVCDCIVKDSINFLDHINGKKHQRNLGMSMKVERSSLD QVRKRFEHNKKKLDEQKKEYDFEERIKELKEEEEKQKVYRKEKKKERKRKAEDAEPSSDM AVVMGFSGFGTTSKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--- ------------------------------------------------------------ ------------------------------------QFPLNAMYSKPANKQEEDSMRAYI QQLRQEMGIRICDKVFDPETDKPSKWWMCFSKRKFMDKSLFGPG-XXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX----AICVLASDSVTGVISFVQDGATIVEGTVKGLNPGKHGFH VHALGDTTNGCMSTGPHFNPKGLEHGAPEDEVRHAGDLGNVIAGKVSLKDAHIPLGGPNS IIGRAVVVHADPDDLGKGGHELSKSTGNAGARIACGIIGF-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------KIEPVKLMKRLWGDQFYNYVRGFTQYILDPI YKVFEFCMPKEEAIALSEKIGVKLTVEEKDNQEKQLMKVIMRKWLPAGDALLQMITIHLP SPVTAQRYRMELLYEGPHDDEAAVAVKNCDASGPLMMYISKMVPTTDKGRFYAFGRVFSG IVQTGMKARIMGPNFIPVKTIQRTILMMGRYTEPIEDVPCGNVCGLVGVDQFIVKTGTIS TFENAHNMRVMKFSVSPVVRVAVECKNPADLPKLVEGLKRLAKSDPLVQCMIEESGEHII AGAGELHLEICLKDLEEDHACVPIKVSDPVVSYRETVSEESDRVCLSKSPNKHNRLYMKA VPMPDGLADDIDRGKITPRQELKERARYLAETYEYDATESRKIWCFGPEGTGPNIVVDVT KGVQYLNEIKDSVVAGFQWASKEGVLCEENMRAVRFDVHDVTLHADAIHRGGGQIIPTAR RCFYACVLTAKPRLMEPIYLVEIQSPEGAVGGIYGVLNRRRGHVFEENRIIGTPMFVVKA YLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILIVNETRKRKGLKEGIPPLDNFFDKLX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------KEDGVEKIYPVNAIA FHNVYSTFATGGSDGYVYIWDGFNKKRLCQFHKYPTSISSLSFSNDGSILAIASSYQFEQ GMPENSIFIRRVSDQETKPKMDFQHRPGGKTGVGGVASASDANRDRRERLRQLALETIDL NKDPYFMKNHLGSYECKLCLTLHNNEGCYLAHTQGKKHQANLAQRAAKEAKDAPAQPAPE RPRVDIRKFVKIGRPGYKVTKQRDPESTQQSLLFQIDYPEIVEGVYPRHRFMSAYEQKME PPDKRWQYLLFAAEPYETIAFKVPSREVDKDGKKFWTHWNKETKQFFMQFAFKMEMKSLP PPPPPKMPPPPTMDEESEAYRLWRVRKTVMQLCHDRGYLVTQEELDQTLDQFKDLFGART GDHK--RSNLIVLVAHTDDPTDQMFVFFPDEPKVGIKTIKSYCSRMQEENISRAIIVVQQ GMTPSAKQSLVDMAPKYILEQFLEAELLVNITEHQLVPEHIVLTPDEKKDILERYKLKES QLPRIQQGDPVARYFGLKRGQVVKIVRPSETAGRYVTYRLVV------------------ ------------------------------------------------------------ -------------------VINKNNKPIVQVDVNSETKTFTPEEISAMILIKMKETAEAY LGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKKEGEKNI LVFDLGGGTFDVTLLTIDNGVFEVLSTNGDTHLGGEDFDQRVMDYFIKLYKKKKGKDIRS SNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMK PVQKVMEDADLQKNQVDEIVLVGGSTRILKIPQLVKEYFNGKEPSRGINPDEAVAYGAAV QAGVLGG-----------------------------------------QIFSTAADQQPT VTIQVFEGERPMTKDNHLLGKFDLTGIPPAPRGVPQIEVTFEIDVNGILRVSAEDKGTGN KNNIVINNDQNRLSPDDIDRMINDAEKFAEEDKKVKEKVEARNEVEGYAYSLKNQIGDKE KLGGKLSDEEKETIETAVNDAISWLEKNHDAEVDDFKERKKQLEEIVQPIVSKLYQGQPP P--EDERDELDSAIEDPELEAIKARVREMEEEAEKIRQMQNEVEKQMSIEDKLDADGRSV WIGNVDYGATAEELEAHFHGCGAVSRVTILCDKFTGHPKGFAYMEFSEREGVDLSMALDD SLFRGRQIKVTPKRTNRPGISSTNRPPRGRGGRARA--HYGGYAPRAPRGGRFRPRRPHY YSPYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXPKVGINGFGRIGRLVMRVALEKLEVVSVNDPFIDLEYMVYMFKYDSTHGR YKGTVALIVDGRPISVHNARDPKEIPWGADGAEYVVESTGCFLSIEKAGAHIAGGAKKVI VSAPSPDAPMFVMGVNQEKYDKTMNIISNASCTTNCLAPLAKVINDNFTIIEGLMTTVHA FTATQKTVDGPSSKDWRGGRTAGTNIIPSSTGAAKAVGKVIPALNGKLTGMAFRVPVPDV SVVDLTVRLEKAAPYDAIKAAVKGPMKGILAYTDEQVVSSDFITSSYSSIFDAGAGISLN DHFVKLVSWYDNEYGYSTRVIDLITYIYQRD----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------VGYDDIGGCRKQLAQIK EMVELPLRHPQLFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSK LAGESESNLRKAFEEAEKNAPAIIFIDELDAVAPKREKTQGEVERRIVSQLLTLMDGLKQ RAHVIVMAATNRPNSIDTALRRFGRFDREVDIGIPDATGRMEILRIHTKNMKLADDVDLE QVARETHGHVGSDVAALCSEAALQQIREKMDLIDLEDE---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------SDYDPVPEITRTHFEEAMKFARRSVTDNDIRKYEMFAQTL QQSRGIGT---------------------------------------------------- -------------------------------------GTKIFTASCDKTAKMWDLGSNQF IQVAQHDAPVKTVHWIKANSYTCLMTGSWDKTLKFWDTRSPNPMLTLSLPERVYCADVVY PMAVVGTAARGVIIYQLDNQPSEFKRMESPLKYQHRCVSIFVDRKTNSPVGFALGSIEGR VAIQYVNPTNPKDNFTFKCHRSTSQDIYAVNDIAFHPAHGTLATVGSDGRFSFWDKDART KLKTSEQLDQPISCCCFNAQGNIFAYASSYDWSKGHEGFDPQKMKPHIFLRSCFDEMKQS QKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMDD SDILTTLKILIIGESGVGKSSLLLRFTEDTFDPEQTATIGVDFKVKTINVDGNRAKLAIW DTAGQERFRTLTPSYYRGAQGCILVYDVSSKQSFTKLDNWLSELETYSTKHEIVKMLVGN KIDKERREVSRDEGLRFARKYHMLFIEASAKTKGGVQCAF-------------------- ---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLGQIRLAAAPQMKKFSIYRWN PDQPGDRPHMQTYEIDLNKCGPMVLDALIKIKNEIDPTLTFRRSCREGICGSCAMNVDGG NTLACICKISD--SSSSKIYPLPHMYVIKDIVPDMNNFYAQYKYIKPYLQKKDMNEADIG KKQFLQSPDDRAKLDGMVDCILCACCTTSCPSYWWNGDKYLGPAVIMQAYRWIMDTRDDF KQERLMQLKDEWSLYRCHTIMNCTKTCPKGLNPGAAIGEMKKLMLGYSSSGIPKQXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMAETAGKTITC RAAVAWEAKKPLSIETIEVAPPRAGEVRIKILYSGVCHTDAYTLSGCDPEGLFPVVLGHE GGGIVESVGEGVKTVQPGDHVIPLYVPQCGECKFCKNPKTNLCQKIRVTQGQGLMPDGSS RFTCNGKTLFHFMGCSTFSEYTVVAEISVCKVDATAGLDKVCLLGCGISTGYGAALNTAG VEAGSTCAVWGLGAVGLATIMGCQKAGASRIIGIDINPTKFDIAKQFGATECVNPTEHSK PIQQVLVDMTDGGLDYTFECIGNVQTMRAALEACHKGWGVSVIIGVAGAGQEISTRPFQL VTGRSWKGTAFGGWKSRESVPQLVTQYLAGKLKVDEFVSHTMNLEKINEAFELMHKGDSX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXX--IQIRRVLLSDPSQVPSDLSSTPGGTLFSTTPGGTRIVYDRSFLLECRNSPLA NSPPVGLPQIPGVT--PPPGKRKEIYKYEAPWTVYSMNWSVRPDKRFRLALGSFMEEYNN KVQIVSLDEDTSDFVSRNTFDHPYPTTKIMWIPDSKGVFPDLLATSGDYLRVWRVTRLEC LLNNNKNSDFCAPLTSFDWNEVDPNLLGTSSIDTTCTVWGLETNQVLGQVQGHVKTQLIA HDKEVYDI---------------------------------------------------- -------------------ARVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQAL IWDIQQMPRAIEDPILAYTAAGEINQIQWSSTQPDWIAICYNNCLEILRV---------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------PQEERLALMARIQNAGTEVVEAKAGAGSATLSMAYAGNKFVTSILQALHG ESGIIECAFVRSDETEAKYFSTPLLFGKEGVEKNLGLGKMIEAEVNAVKAGMPELQKNIK KGEEFVAKN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------IGDKFSSRHGQKGICSRKVPMEDMPFT ESGMTPDIIFNPHGFPSRMTIGMLIEFMAGKSAALNGCCYDATPFTYTEEDDPISECLKK VGYNYYGTERMYSGTNGRELEVDIFIGVVYYQRLRHMVYDKYQVRTTGAYDQITKQPVHG RKKGGGIRLGEMERDSIISHGASFLLQDRLFNCSDGSEVRACTKCGSLAASVTATRRWRC RLCSQADTVVKIRVPQVFAYLVAELASVNI---------ELPGGFVFDNCTRNAVFQKGA KPPKAVKTGTTIVGIIFKDGVVLGADTRATEDTIVADKNCSKIHYIADNIYCCGAGTAAD TEMTTRLISSKLELHRLNTGRTPRVCTANRMLKQMLFRYQGYISAALVFGGVDPTGPHLY TVAPHGSTDSLPYVTMGSGSLAAMAVFESRYKPNMDLDFAKTFVRDAIAAGIFNDLGSGS NIDLCIITKKVEYLRPYDGANKKGQRQGKFEYRPGTTVILSERVKHFAAGELMSKVTFKI ILTSDPKLPYKVLSVPEITPFTAVLKFAAEE----------------------------- ----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- --------------------FCWPCLHQWLETRPNRPTCPVCKAGISKDKVIPLYGRGNA NQQDPREKVPPRPQGQRTEPDNSNTFNAFGFGFQMSFGIGAFPFGLFASVFNVQDGRPAA PPPGSAQHPDDIFLSRIFLFVAIVFIFWLMIA-YSLMCKQEQAHDDSIWSCAWARSEKDG TENIVTGSVDDIVKIWKWSNLELRHKLEGHLLGIISVDINREGTVAASSSLNSQIRLWDI ETGRQIKEIDAGPVDAWSIAFSPDSRFLASGSHTGKINLYGIESGKREVQLDTRGKFALS IAYSPDGKYIACGAIDGIIYIFEVVSEKLLEGHAMPIRGLSFSPDSKLLVTASDDSHVKI YDVVQGNLIGTLSGHGSWVLNVSFCPDNIHFVSCSSDKTVKVWDSSSRQCIQTFHDHTDQ VWCARYNSSGSKIVSVSEDRAVHIYDCP-ETDEEFDRRYERFFNRPDIDGWEIRKAINDL QGHDLVPEPKIVIAALKACRRINDYALAVRYLEALKEKSGPKVTEIWPYMLKEIGPTLKE LGILTPEEMGYDKPELALRDVYDMVVRLRGLPWSVGKEEVASFLEGCNV----SDVHFTF TRDGRPSGEAYVELASEEDVQGALAKNQQHMGKRYIEVFRSKHSEMEWVLRKDG------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------QYSNILSPICVDAVLRVIDPARDSNVDLHDIKIIQKLGGTLEDTELI DGLVFNQRSAGTGGPTKVEKAKIALIQFCISPPKTDMENQVILSDYTQMDRVLRDERQYI LNIVKQIKKVGCNVLLIQKSILRDGVSDLALHFLAKMKIMVVKDVEREDIEFVCKTLGCH PIASLDHFQAESLGTAELVEEVSAGDSKIVKVTGIQNPGRTITILCRGSNKLILEEAERS IHDALCVIRCLVKKRALIAGGGAPEIELSFRLAEYSHTLTGMEQYCFRAFADALEVIPFT LAENAGLNPIATVTELRNRHAQGEKTFGINVRKGAITNILDENVIQPLLVSMSAVHLAAE TVRSILKIDDIVNCMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKTKFGGLKDEDRVF TNLYGRHDWRLKGALKRGDYYKTKEILLKGIDWIQGEIKKSGLRGRGGAGFPTGMKWSFM NKPDDGRPRYLVVNGDEGEPGTCKDREILRHDPHKLIEGCLIAGRAMLAKAAYIYIRGEF YNEASNMQIAIREAYEAGLIGKNACGSGYDFDIYLHRGAGAYVCGEETSLIESIEGKAGK P------------------------------------------------NVMMEFDDLTA KQSALGTAALIVMNKSADVIQCISRLMKFYKHESCGQCTPCREGCNWMDKIVARFAVGKA RPEEIDMLYELSKQIEGHTICALADGAAWPVQGLIRHFRPEIEQRMKEY----------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------M DEIVEGTVGTLHILAREAHSRAIIRSLKCIPLFVQLLFSMNENIQRVATGVLCELAAEKD GADAIEQEGASVPLAQLAQSCNEAVASYAGALLFRLNEDKPPEYKKRLQAELGANVFRPD AMSADLQWMVIRNTSSFLMKRRQFSKEPNNLKGRNSFRYNGLVQRKTVGIEAFADGKGVV LVTRSCVRKPVKKYRRTELKRGSRKTFRTIRKLVSGNTGRRDLKMAAVRRASALLKSQKP VLVKKTRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSKLDSGQREQLMEQVKA QIAVANAQELLQKMSDKCFKKCVSKPGTSLDNSEQKCVAMCMDRYMDTWNLVSRTYAQRL QKEKSRIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- -------------------GGGRGG--GGRGGMRGGAKVTIEPHRHEGVFIARGKEDALV TYNLVVGESVYGEKRISVEEGKKIEYRAWNPFRSKLAAAIMGGIGNIYIKPGSKVLYLGA ASGTTVSHVSDIVGPEGLVYAVEFSHRSGRDLLNVAKKRTNIIPIIEDARHPHKYRMLVG MVDTIFADVAQPDQARIVAINAHHFLRNEGHVVISIKANCIDSTAVAEAVFASEVEKLKK EKVKPLEQITLEPYE--------------------------NRLAKSGKGAGVGLGILAA AGGVIYGLSQAMYTVEGGHRAIIFSRIGGIQPDIYREGLHFRIPWFQYPIIYDIRARPRK ISSPTGSKDLQMVNISLRVLSRPDSAMLPAMYRQLGIDYDERVLPSICNEVLKSVVAKFN ASQLITQRQQVSLLVRKELTDRARDFNIILDDVAITELTFGKEYTAAVEAKQIAQQEAQR AQYVVEKAKQERQQKVVQAEGEAAAAKLIGEAISKSPGYLKLKKIRAAQNIARTLAGSKN RVYLDASTLIVNVGSKEFDENLEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- -------------------------------------SGTSKGCCFLTFHTRQSALTAMK AVHGVRIMPGGKRPLQIKPAVGAEEKEEDRRLFVGMIGKQTSETELRQMFGVYGNIESSI ILRERDGSSRGCAFVTYTARKSAVKAIGALNHARTMEGCHKPLVVKFADTQKDKEMK--- ---------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------KFLDYTTDNMSIYPSPSGVLIALD LAYNLHSAFGNWFPGCKPLIQQSMAKIMKANPALYVLRERIRKALQLYSSEPTEPYLSSQ NYGELFSNQIIWFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSV WAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKG SELQLPFQACLKVEKFGDLILKATE----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------PNELP QLSPQDITTHAKVMSDNPIWDGEKTIVITCSFTPGSCSLTAYKLTPSGYEWGRQNKDSGN NPKGYLPSHYEKVQMLLSDRFLGFFMSPAQSSWNYNFMGVHHDPNMKYEIQLANPKEFYH ELHRPSHFLNFRSLEEGGDREDLY------------------------------------ ------------------------------------------------------------ --------------------------------------------------------AGKI GIVSRSGTLTYESVHQTTLVGLGQSLCVGIGGDPFNGTNFIDCLTLFLQDKQTEGIILIG EIGGAAEEQAAEFLAKNNGPGKKPVAAFIAGLSAPPGRRMGHAGAIISGGQGGAKEKIEA LKKAGVEVTMSPAQLGSTILQAMKKAGKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFTKFVEIGRIAYVA FGPDAGKLVVIVDVINQSSALVDGPCSGVKRQAMSFKQMHLTQFVIIAHSARTGTVKKAW EKAEVDKKWAETTWAKKIESREKRKTLTDYDRFKLMKAKQMRNRLIQVEFGKLKKQARKT CPLLLRVFCNTGRHCAMNDYARGGTPSNELQIYTWMDATLKELTSLVKEVNIEARQKGTF FDFGIVFPDTRSNAYRIPEIGSTCCGRKG------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------DFQFYPPRLFELLDKEIYYYRKSIGYRVPKDPDLGSDAERVR REEQKKIDEAELLTEEEIAEKDDLLKGFANWNKRDFNQFVKANEKYGRDDIESISKEVEG KTAEEVMEYSSVFWERCNELQDIERLMAQIERGEAKIQRRVSIKKALDAKMARYRAPFHQ LRIQYGTNKGKNYTEEEDRFLVCMLHKLGFDRENVYDELRTAVRQAPQFRFDWFIKSRTA MELQRRCHTLITLIERENMELEEKEKAERKKESKPSWAEQVERGDDEVLPPASEEFDEVS GIKKIIEYKFNEDGKKVKIVKTYKIETRKVSQSIAKRKNWKKFGAASGDPAGPNPANTVE DIFLQFIHAKDLPDDDPLSRLKVQCRICKGDHWTTKCPYKDSLAPLQESLQRAGKYVPPS LREGGNRKGESMALDEAATIRVTNLSEDTRESDLQDLFRPFGHIARIFLAKDKVTGQSKG FAFINFHNREDAARAIAGVSGFGYDHLILNVEWAKPSXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------------- ---------------------EKTGHSGTLDPKVTGCLIVCIERATRLVKSQQNAGKEYV GIFRLHSAVDGERSILQAVEQLTGALFQRPPLISAVKRQLRIRTIYESKLIEFDKDRNMG IVWVSCEAGTYIRTLFVHLGLILGVGGQMQELRRVRSGIQSEKDGMVSMHDVLDAQYLYD HHKDESYLRRVIRPLETLLVSHKRIILKDSAVNAVCYGAKIMLPGVLRYEDGIEVNEEIV IVTTKGEAVALGIALMTTAVIATCDHGIVAKIKRVVMARDTYPRKWGLGPVASKKKQMIK DGLLDKHGKPTDSTPKDWNKSYLDYNSHKKRKQTADTSEKKHKKKHKKXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------ETTENIRVTVMPFYIGEVQQTQVYWWRYCIRL ENLGEETVQLRERHWRIFSLSGTLETVRGRGIIGKEPIFSKSQPAFQYTSHVSLQAPSGH MWGTFKMERQDGSTFECRIPPFSLESKHEDG----KSANNYNRQNWEDAEFPILCQTCLG DNPYIRMTKEKYGKECKTCARPFTVFRWCPGARMRFKKTEVCQSCAKMKNVCQTCLLDLE YGLPVQVRDAALKIHDEIPKSDVGKEYYQQNLDKEIAGTDGTVAVGAVGKALAPSDILLK LARTTPYYKRNRPHICSFWVKGECKRGEECPYRHEKPTDPDDPLADQNIKDRFFGINDPV ADKLLKRYDTMPKLDLPEDLPVYLMIRRKKTTIFIEALENTKVVELKKMLECLTRKLAED VRLFREMKNLSDLGFTNGVCTPQSPGTIGLVYREFELVDITPLSTPPELPEVMK------ -----HLYRYQAVLLRARFDEHKDEDMVKAKQLLEEGEKELFLNQHPQPFKFPDSHGGVG FGRKIVVPDWILDMWHPLERAAYPEYFARRDQRKKEFIERWEKKYGKAEMEDYIKIEKIG EGTYGVVYKGKHKKTNRIVALKKIRLESEEEGVPSTAIREISLLKELVHPNVVTLEEVLL EDGKLYLVFEFLSMDLKKYMDSLPAGQFVDKMLVKSYLYQILQAMLFCHQRRIIHRDLKP QNLLIDSQGIIKLADFGLARALCIPVRVYTHEVVTLWYRAPEVLLGSARYSTPVDIWSIR CIFAEMASRRPIFRGDSEIDQLFRIFRTLSTPNEESWPG--------------------- -----------------------------------RLLSALGKVGLGLAVTAGVVNTALY NVDGGHRAVIFDRFAGVRQTVVGEGTHFIIPWVQRPIIFDIRSQPRSVPTVTGSKDLQNV NITLRILFRPVADKLPDVFTNLGIDYDERVLPSIINEVLKAVVAQYDASELITQREMVSH KITDDLTTRAGQFGIILDDISITHLTFGREFTEAVEMKQVAQQEAERARYLVEREEQMKL AAIIRAEGDSAAAALLAKEFAEAGEGLVELRKIEAAEDIAYRLSQSPNVTYLPSQLKALI SLPMKTINQYQIVKLIDGVEVSVKSRKVIVRGPRGTLRRDFRHMAVDIKKVGKKQLMVEK WFGIRKELAAVKTVCSHIENMMKGVTKGYRYKMRSVYAHFPINVGVTESNTLVDIRNFLG EKFTRQVRMLPGVSFIASKDMKDEFVLEGNDIELVSRSAALIQQSTTVHRKDIRKFLDGI YVSEKGTVVE------------------------------------------GESGKSTF IKQMKIIHENGYSKSECLGYVPVIYSNTIQSMMAILRAMGRLKIGFANPEVEKDARQFFN AVSKSDDAPLTVELATVMTRLWKDGGVQDCFRRSREYQLNDSAEYYLESLDRISQPSYVP NEQDVLRTRVKTTGIVETRFTLRGFHFEIFDIGGQRSERKKWIHCFEGVTAIIFIVALSE YDLSLIEDQEMNRMMESMQL---------------------------------------- ------------------------------------------------------------ --XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXX--------------------------------------------------NIRNLAM EKVASQVMFPCRYVCHGCDITLPYTDKANHEQSCECRPYACPCPGASCKWQGSLDQVMPH LLSMHKSITTLQGEDIVFLATDINLAGAVDWVMMQTCFGHHFMLVLEKQERGEGNQMFYT VVQLVGTRKQAENFAYRLELNGPKRRLTWEATPRSIHDGVQSAINSSECLMFDTNVAQLF ADNGNLSINVTIYLCXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXX---------------------------------------------FTKN LVQQFVMTMSASADVLALAKIEVKLDQIPEGKNMTFKWRGKPLFVRHRTPEEIEREQAVV PGTLRDQQHDNDRIKKPEWLVVIGVCTHLGCVPIANQGEYGGYYCPCHGSHYDGSGRIRK GPAPLNLEVPDYEFPDDNTLLVGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXX------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------KAVDWWALGVLIY EMAAXYPPFFADQPIQIYEKIVSGKVRFPSHFSADIKDLLRNQLQVDLTKRYGNLKNGVA DIKQHKWFSNTDWIALYQRKIEAPFLPKSKGPGDPSNFDTYEEEPLHISSSEKCAKEFAD FMLADTLLILFISVATALLGEGLTWLMVYRTSKYQKLKSEVEKQSKKLEKQKETIGETSD RSQKKKLERQEEKLKTNNRDLSMVKMKSMFAIGFAFTALLSMFNSIFDGRVVAKLPFVPI SWLQNISHRNLLGEDYTDCSFIFLYLLCTMSIRQNIQKMLGFAPSRAANKQGSGFFNTXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------------- ------------------------------------------LIFCDIHNIHVMRESLRK LKDVCYHPVDDCHWLSNIESTHWLDHIKQILAGAVRIADKVENHKTSVLVHCSDGWDRTA QLTALAMLMLDPFYRSLTGFEVLIEKEWLSFGHKFAQRVGHGEDKHSDADRSPVFLQFID CVWQMTRQYPNAFEFNELFLVTVLDHLYSCMFGTFLYNSEQQRTKENVKTTTVSLWSYIN SQRELYTNPLYQHVLFPVASLRRLEPWTGYHLRWNPCAIPQEPVHARNLELLLAKQQLLK RLEELQKEQQAR-GSFRPFIPHMPFDLIQCENVFPRAKPAPDDKIFTEALLKRSQELTPG TQEQAAVLNLVTKIQSVLDNLVVAPTLFDAAQLEEVRQVGSHKKGTMMAGHEVADIVVIL KTLPTLEAVQALANKVTDDLRSGDPHEAFSALTNEGGFEISSSEATVKVLIATIPPNLKK LDPSLHLDGKIMQGHLTAIRHAR----------IKVLVRLLRDLKNRFEGFSALTPWIID LLAHFAVMNNPSRQPLPINVAFRRCVQLLSAGLFLPGSAGITDPCEQGSVRIHTVLTLEQ QDQICYTAQTLLRVLSHGGYKQILGFEEYPSITTDMTVWDGVVVTPSDKAYEKKEEXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXMAQYVQLGPRAVDKAVPKLQTFWQYARVELRPPSELPQIQ KSFVDLIAARTQKWRKLTVREAALVAFEVACWFFVGEVIGKGHLIGYQIPGAMDFEAHVI PQFYFKLPSEDEPLLQKLREESRAVFLQRRSRELLDNDELQALWTLLDKHQTPPLINDEQ MINYEDFLKVGSESCAKCKPFFKASVFAKLLGNDPYGRISVMQFFNYVMRKVWLHQTRIG LSLYDVAGLGYLRESDLENYILELIPTLPQLDGLEKSFYSFYVCTAVRKFFFFLDPLRTG KVKIQDILACSFLDDLLELRDEDLPKDMQESNWFSAPSALRVYGQYLNLDRDHNGMLSKE ELSKFGTGTMTSVFLDRVFQECLTYDGEMDYKTYLDFVLAIENRKEPQALQYLFRLLDVQ GKGFLNIFDLNFFFRAI------------------------------------------- ---------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGSKAFTKGRKIAYG ATTGLVGLGVALETYELHPSKYNWSHGGMLQSFDHASIRRGYQVYKQVCAACHSMNFMYY RNLVGTVMTEDEAKAEALEVMVTDGPDEQGNMFQRPGKLSDRFPRPYPNDEAAKAGNNGA LPPDLTFITGARHGGEDYLFSLLTGYCEPPAGITVPEGMHYNPYFPGGLISMARSLFNEL MEYEDGTPATASQMAKDVSTFLRWACEPEHDDRKRMGIKVMMIGLLFVAFYYKKHKWTLI KSRKIAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSDDGS DEERGQNLGEYAGERNEKEQRHGHGKAVLPNGDTYEGMYDCGLRQGTGTYRFKNGARYSG EWFKNKKHGQGLFIYPDGS-YEGSWVDDQRCGTGKFYYVNGDIYDGEWRGHHRHGFGTYT YADTGSRYVGSWRDGKREGHGELI----------------------------------XX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXX------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------HIGSQNMVAIPVYLRHNISIREGSAGRLDIT VGPKQTMGKTVENVLIEIPFPKSVLNVTLTASQGKYSFDPVTKTMSWDVGKIDPTKLPNI RGNINLQTGCPPPDANPTVSVHFTISQMAVSGIKVNRLDMYGEKYKPFKGVKYVTKAGRF QVRTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- -----------------------------------------LNNYAQAEGILYCKTDYGK AILAKNSQIDAMFVHRDTPENNPSIPFKFTAENLKRAQSIIGNYPKGFECSAVMPLLDLA QRQNGWLTISAMHYVAEMLKMPKMRVYEVATFYTMFKREPVGKYFVGVCTTTPCMLGGCG CAPILDAIKXKLGIDVGHTTPDKMFTLAEVECLGACVNAPMLQINDTYYEDLTVKDVNEI IDELKAGKTPKAGPR---NGRFALEPAGGLTTLTTPPYGPGFRVRSDLXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDESKFIQYKGPVPGVKYPLNE ICDGWPLEYCEFHPNYEKAKEWMDKNLTDDMRDLYLKRQTRGGRGVVKLKQKQDEKRICL SRACRGKRKFVTVVTGLSTYEIDLKVASKFFGGRFACGSSVTGDDEIVIQGDVKDDLFDV LTEKWPQIDEDSIEDLGDQKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXMPRFVPYLTKEKEDELRRIASAIVAPGKGILAADEST ATIGKRLTSIHVENVEENRRAYRQLLFSCLSEHISGVILYHETLYQKADNGQTMGEMLRA HGIIPGIKVDTGTVPLLGTDGECTTQGLDGLAERCAQYKKDGCDFAKWRCVLKISDHTPS YLAMLENANVLARYAMICQQNGLVPIVEPEVLPDGEHDLVTAQKITEQVLAFTYKALADH HIFLEGTLLKPNMVTAGQSCAKKYTP---------------------------------- ------------------------------------------------------------ ------------------YIKSLPKCVKRRLKALKRLQADANKVESRFYEEVDALERKYA ALYEPFFERRREIVAAQVEPNDDECNWPSDEEEEDLKAKIEEDETTKGVPDFWLTVFKNV DMLAEMIQPHDEPILKHLQDVKLKLNTGFILQFVFEPNDFFTNPILTKEYTIRFSVEDDN PLGYEGPDIIKCAGCTIDWKKGKNVTVKVVKKVQKHKGRGTKRTVTKTVQNDSFFNFFNP PQVTEDEPDEETEALLTADFEIGHFFRESIIPRAILYFTGEAIDEEEEGDDEEGEIILLK EGTDTSQGKPQLISNINACQAIVDAVRTTLGPRGMDKLIVDGRGKASISNDGATIMKLLD VVHPAAKTLVEIAKSQDSEVGDGTTSVVLLAGEFLKQCKPFVEEGVHPQVIVKAFRRASG LAVQRIREIAVQIKENPEQHRELLKKCAATALNSKLVARQKDFFANMVVDAVMLLDELLP LNMIGIKKVQGGALEDSLLVGGVAFKK--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GGGAIEMELSKYLRDYSRTIAGKEQLL IACMAKALEVIPRQLCDNAGFDATNVLNKLRQKHAGRWYGVDINNEDIADNFEACVWEPS VVKINALTAASEAACLILSVDETIKNPRSSAEPAGRGRGRGRPFKGNNMIPNGHFHKDWQ RYVRTWFNQPARKQRRRDNRKKKAAAIMPKPVAGALRPVVHCPTFKYHTRVRAGRGFTLE ELKAAGIKKREARTIGIAVDFRRRNKSVESLQKNVQRLKEYRAKLILFPKKISKPRKEDS SAEELKLATQLTGPLMPIVSVPRKEKARAITDPERKFSAFVALRQARAHKRLAGRRAKKA KEGMPNIKIFSGTSHQELAQKICDRLGIDLGRVTTKKFSNQETCVEIGESVRGEDVFIVQ SGCGEVNDMIMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSPISAKLIANMLSTA GADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENIPEWRNSIIVSPDAGGAKRVT SIADKLNVDFALIHKERKKANEVASMVLVGD----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------SRRRIRSINKLIRIGRDECVVVIRVDKDKGYIDLSKRRVSAEEVVKCEEKFAK AKTVNSILRHVAGLMKYEQDSQLEELYQKTAWMFDRKYGKPGASFEAFKHAVTNPEILQE CEIDDVTREKLIENIRRRLTPQAVKIRSDIEVACYGYEGVDAVKSALLSGLNMSTEDMPI KINLIAPPLYVVTTNTLERTEGMARGQQKIQSQQKNAEKQAKLKADQKKSAAAALVYSCA VCKTQMPDPKTYKQHFENKHPKNPMPEELKSVXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMRPLTDEETKLLFE KLSKYIGENVKMLIDRPDGVYCFRLEKDRVYYVSEELLKKAGHIARDHLISFGTCFGKFT KSSKFRLHITALDFLAPYAKFKVWVKASAEQQFLYGNHVMKSGLGRITENTQQYQGVIVY SMNDIPLGFGVAAKSTADCRHTDPMAIVVFHQADIGEYIRSEDTLXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------IGEADKEFNAILAVVQEIHRISQQYGISTGYENPYSYITGQDLSSKWHEVKQLV PDRENVLRNELMRQQNNERLRRAFAQKANVVGQWIERHLDAVATASMQRGKLEENLSRLQ ALDKEVHAFKPNIDELERYNQDIHEAMIFDNRHTPYTMETLRVGWEQLLTSVARNVNEVE NQILTRDSKGITNQQLEEFRKSFLHFDKSRTRRLDPKEFKSCLISLGYNIKDDRQGDSDF QRIMTAVDPNNFGYVTFEAFLDFMTREA-------------------------------- ----------------------------------------NKLNIDKLEHRXKRVLIRVD FNVPMKNGQITNNQRIVAALPTVKYALEKGAKSVVLMSHLGRPDGKKVDKYSLKPIVDEL KKLLAKDVLFLNDCVGPEVEAACKDPTPGTVILLENLRFHIEEEGKVTAEDGSKVKADPK KVEEFRASLSKLGDVYVNDAFGTAHRAHSSMVGCQLPQRASGFLLKKELTYFAKALEHPD ------------------------------------------------------------ ------------------------------------------------------------ -----------------FEFDNFSKGTKSMMDAIVKTTAAGSTTIIGGGDTATCCAKYNT EDKVSHVSTGGGASLELLEGKVLPGVDALSAAXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXX------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------GKNPGGNTMMNMQIPGLSMDRVATEVLCLMNMVMPEDLEDEEEYEDIIE DVREECGKYGRVRSLEIPRPIKGVEVPGIGKIFVEFESIPDCQKAQQALAGRKFANRVVV SSYYDVEKYHHREFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX ------------------------------------------------------------ --------------------------IIIQQGDRGDSFYIVLRGKVSVLISADLTSLV-E GDAFGELALLEDSTRNATVIADVRTDLIVISRELYNRSLCSWQAAELQAKHSFVQQHTLF RTWPTKYKRQLAMSLHREQVTFDTTVVHQGQTVNNIYFIIRGQCXL-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------IYLQNWTHVTTYVSKAETTSFLTENKESNQAVVTKLNIASGL GELMCSKYKAAARLFLSASLDHCDFPELISPNNIATYGTLCAMATFDRHEIQRLVLNSSS FKLFLELEPQLREIVHKLHNSQYASSLKLLNDMKDNFILDLYLASHVESLFAQIRSRALC QYFSPYLSADMRKMAVAFNTTVNGLEEELMQLILDGKISARIDSHNKVLYVKDLDQRSIT FEKAFAMGEEYKMRSKALVLRAAVVKN--------------------------MTSKNQL IDKAEDIADQVLRHGKHILPHVARLCLVSTFIEDGVRMWLQWSEQRDYMNSTWNCGWILA TLFVVVNLSGQLGASSVILLRRYVVVGCCVLLGIMVLQTVAYSVLWDVKFFMKNMAVVGG VVLLIAESKADGKSLFAGLPSAGDRNPQTYMQLGGRILLVAMFLTLLRLDVSSVSLIQDV VGTALVVLIAVGYKTRLASLVLVTWLLTVNIYSNAWWMLPEYQYNRDFVKYDFFQTLSVA GGLLL------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------RAIAEDIDIFTDY MG---EATPDAGEHLRITRHFADERWSRHRTVTSLDWSPEFPELLVAGYDGNPEAPHDPD GIAMVWNLKFKKTSPEYVFHCQSPVMATCFTPFHPNLVIGGTYSGQVVLWDTRSSRRTPA QRTPLSATGHTHPVYCVNVIGTANAHSLATISTDGRMCFWSLDMLAAPQDSLELQYRQSK VAATCFSFLAGDSNNFVVGSEDCAVYAGARHGTRAGASDIFEAHCGPVTGVDCHSVPGPV DLTSY------------------------------------------------------- ------------------------------------------------------------ ------------------IQQQLLAATQAIEQQVDSEIQKLDKADEDELEALRRRRIEGL KTAQKQRQDWQAAGHGTYEEIADEAEFFAVCKKSRFVVCHFFRSSTPRCKIVDKHLSLLA PRHLETRFVRIDAERAKFLVDRLRVKIMPTICLAKDGKTVDYIAGFDDLGGTDEFTTEVL EWRIARAAVIEYSGDLLNPPAAAGQKKTIRDGQEDDXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQS RKQTPSDFLKQIIGRPVVVKLNSGTDYRGVLACLDGYMNIALEQTEEYVNGQLKNKYGDA FIRGNNVLYISTTKRR-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXTVRPVNAVVKQNLIDFGQYVGQCLPKYVQKVQVTNGDELEILIHPEGVIPVITFLKD HTNAQFTNISDITAIDVPSRQYRFEIVYNLLSIRFNQRVRVKTYTDELTPVQSITSLFHG ANWYEREVWDMYGVFFANHPDLRRILTDYGFEGHPFRKDFPLVGYVEVRYDDEVKRVVVE PVELIQEWRKFDLGNPWESFPAF---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------- --------------------------------LSKGEAVCLDRCVAKYLDMHDRIGKKLT SITMADQETAQKLQAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------VQHNVLVAEVTE QLKARFLPSPVVIKKRIEGLIEREYLSRTTEDRKIYTYVAXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXPLRVLITGAAGQIAYSLLYSVAKGDVFGTSQPIALTL LDIEAMQGVMTGVVMELTDCALPLLKSVTPTSDIAVAFKDIDVAILVGAMPRREGMERKD LLKANVRIFKQQGEALSQYAKKTVKVVVVGNPANTNALICKSYAKGIPPENFTCLTRLDQ NRAQSQIAARQDVRNIIIWGNHSSTQFPDVSHAVVVPEAVKDDAWLKGDFISCVQKRGAA VIAARKLSSAMSAAKAVCDHLRDWWFGTKEGQWVSMGVPSDGYGIESGLIYSFPIQIDHT YTIVQGLAIDAFARGKMDATKQELIEERDDALKACXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXMTAPASIPGVPPGLEYLTQIDQLLIHQQVELFEALTGWESNNRYQIKNSLGQQVYFAA EESGVWMRQCCGPSRGFIMHITDNFGQEVIRVVRDFKCCAGWNCCANCSMDIRIEAPVGQ VTGYMRQTCWKTHYLIEDAVFSIVGPCCPCQGLCCRADIEFPIMSSQVGVVSKQXAGVLR EMLID-------------------------------------XXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXGKKITEVTEDNCEVCVKFMTRFVDSIDKIEAAFRKFC KPTKGDDNRFCYYVGGLEESATGMLGEMSKPVSWSMPPDKVCMKLYRKDEQICDLRYAKT FDYSKIDIKKLKVSELKAILSEWGEQCRGCSEKSDYVHMVEELLPRHAPDAAXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXX--------------------------------------------D KLPLRKRDSARVIDSARHAHKITCEPDETIHLKRPEGIEKQFRLKCKKCGLWLYYRHRNQ ITFIVENALVKAGDAKPDIYTQIA------------------------------------ --------------------------------------------------------QPTR GYADMAFTFASPASVNVKQIDVPSFSGSFGILPNHVPLIAVLKPGVITVHEQDGANKRYF VSSGSVTVNDDSSVQILAEEACPVDQLDSQAVRDGAAKAAQDFSSDVAKVEAQIAMECYD ALQRAVDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-- ------------------------------------GAGLRAAFGLSNQGFKTACITKLF PTRSHTVAAQGGINASLGNAEDDKWQWHFYDTVKGSDWLGDQDAISYMCEEAPKAVIELE NIGMPFSRMDNGKIYQRAFGGQSLDYGKGGQAHRACCVADRTGHSMLHTLYGRSLKYDTD YFIEYFATDLIMEDGICKGVMAISLEDGNIHRFRCNNTVLATGGFGRCFFSCTGAHTCTG DGNALVARAGLPNQDMEFVQFHPTGIYGAGCLITEGVRGEGGYLVNSKGERFMERYAPNA KDLASRDVVSRAMT---------------------------------------------- ------------HYNMGGTPTNFRGQVITHNGKDTVVPGLYAAGEGASTSVHGANRLGAN SLLDIVVFGRACAMTIATTHKPGDPAPKLKDNAGENSIANIDKLRHANGSISTADLRLKM QKVMQDHAAVFRDGPTLLEGCKKLAAVYQELNLKVGDRGMIWNSDLIETLELQNLMLNSA MIVFGAEARKESRGAHAREDFPTRLDEFDYSKPTEGQSKKTFEQHWRKHTLATVEPDSGK VTLTYRPVIDKVLDPKKVEVIPPKIRTYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXKIASRYDAEVEREVLGWFKQLLNPGMHKVEK ALKNGQDLVKLAKVIKAKKMGLKHTTLDAPFKQMENIQMFLTFCENYGVPKTNTFQTVDL YEGTNMPQFLSCIQCLGTECQRHGFTGPTIGTRPTEKNVREFSEEQLRAGQLQAGTNKGA SQSMGGVRHVADIRADDMSKEGQSVIGLQAGNKGASQAGMSMGGTRH------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------------MP DTYSFGIEPISCHAWNKDRTQIALLNNNEVQIHKFKWTLTDTLAEHGQRVTGIDWAVNSN RIVTCGADRNAYVWPTLVVLRINRAATCVSWSPQENKFAVGSGARMISVCYFEQENDWWI SKQIKKPIRSTVTCLDWHPNNVLLACGSTDFKARVFSTYIKDVEEKPSSTNWGSKMPFGN LMAELSNASGWIHGISFSANGERLAXVGHDSSV--------------------------- -----------------------------------------------------------G NKERCVRLSTSGVDGQLVVWDVKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSRRYDSRTTIFSPEGRLYQVE YAMEAIGHAGTCLGILASDGIVLAAEKRNTNKLLDEVSFSEKIYKLHEDMACSVAGITSD ANVLTNQLRLFAQRHLLQYGEPIPCEQLVATLCDIKQAYTQFGGKRPFGVSILYIGWDKH HGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQEYKEGETDLKQALDLSIKILSKTLD TNKLTADKVEIATLTRTDSVSRIRILSTAELEALVKKFEEEEAKLEAEKKK--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------DPVRCNSVEEIKALREAHDQFKASLSAAEQDFNQLAQLDKQIK SFNVGPNPYTWFTMEALEDTWRNLQKIIRDRDEELAIEQRRQEENDVMRKQFAGAANTFH QWLTETRAAMMEGTGSLENQLEATKRKSAEVRGQRSQLKHIEDLSAGLEERLILDNRYTE HSTVGLAQQWDQLDQLCMRMQHNLEQQIQACNQSGVSEDSLREFSMMFKHFDKDRTGRLD HQEFKSCLRALGYDLPMVEEGQRD------------------------------------ ------------------------------------------------------------ --------ALQCYQCDSNEDGSCPSWQAFDRNINALVDCMSFEARTPGIFCLKVTRQSPG WFGWKKQTRRCGSRSDTGVAWGCRWVFEDNGVWKETCYCEDQDGCNASNPIDRDDAQNPQ LVSIYAGDIYDYLRQTELKALTGWMRAILVDWLVQVHMRFRLLQETLYLTVAIIDRYLQI PVTKDKLQLVGVTAMWIACKYEEVYVPEVSDFAYITDNAYTKPEIRQMECAILKVLKFEL GRPLPLHFLRRNSKAADADATMHTLAKYLMELSLIDYELVHVLPSEIAAGALCLA----- --------SGYTEHQLQSLICRLCQLVLKKLTAIKTKYQSSKFMRISKLTQLDSQLVRDL A----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------KGSCFER IKMRFGEKRCYFVIGDGHEEDNAADQMVWPFWRIENHSDLVALHRAFELGYLMSALSVSG SRTTGQSVRTQNVMAACSIANIVKSSLGPVGLDKMLVDDVGDVTITNDGATILKMLEVEH PAAKVLVELAQLQDEEVGDGTTSVVIIAAELLKNADELVKAKIHPTSVISGYRLACKEAC RYIQENLTISVDELGRDCIVNAAKTSISSKIIGSDADFFANMVVDAANAVRVPDGKGGFR YPIKAVNILKAHGGSTRESLLVNGYALNCTIASQALPKKIIGAKVACLDFSLNKAKMKLG VQVLIDDPTKLEGVRQRESDITKERIQKILSTGANVILTTGGIDDLCLKYFVEAGAMAVR RCKKMDLRRIAKAXGAVMISTMANLEGEETFEAAFLGQAEEVVQDRICDDELILIKGPKA RTAASVILRGANDFMCDEMERSVHDALCVVKRVLESKTVVPGGGAVEAALSIYLENFASS LSSREQLAIAEFANSLLVIPKQLTVNAAHDSTELVAKLRAFHNTAQTKPDMRDLRWVGLD LINGAVRDNKKAGVLEPAISKIKSLKFATEAAITILRIDDMIKMFPEQKGGRSYQDAVRA GDL--------------------------------------------------------- ----------------------------------------PSDTEPQRAYTSSPGEGGIV SFKDYDRKFSSHVLDWAAFAVMTLPSLGIPFLLWNKSKSKYESMKVQK----------EK YRSVLGLVDGLKTFVEAVANENVSLVISRQILTEFCSNFSSLPDTVGKEVAHFTLDKVQP RVVSFEEQVGLMRQQLSNIYEREQNWREAASILVGIPLETAQKQYTNDYKLETYLKVARL YLEDEDPIQAEAYINRASLLQAESTREDLQIHYKVCYARVLDFRRKFIEAAQRYNELSYK SVIAESERMTALRNALICTILASAGQQRSRMLATLFKDERCQQLPAYGILEKCIL----- -------------------------------------------------LGALLEIPPRK AEKIASQMITESRLNGCIDQIDKIVHFEVQEALPTWDKQIQSLCFQVNSIIEKISVTAPD WLTKTYDSQMSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX >Tubulanus --ERKAVIKNADMPEEMQQDAVDCATQAIDKFNIEKDIAAFVKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQVAVLLFKSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXM SHYKE-GKAPEAPVHRIRITLTSRNVKSLEKVCADLIRGAKDKNLKVKGPVRMPTKILRI TTRKTPCGEGSKTWDRYQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADMDQVM AYVEPAKQFSKDSIRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNII VMAAQISKKRKFVADGVFKAELNEFLTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVL GEKGRRIRELTSVVQKRFSFPEGTVELYAEKVATRGLCAIAQCESLRYKLIGGLAVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGEPCNEYVDMAVRHVLLRQ GVLGIKVKIMLPWDPTGKLGPKRPLPDHVSIVEPKEETIPAAPYSEQKGGKMSKRGRGGT SGGKFRISLALPVGAVINCADNTGAKNLYVIAVQGIKGRLNRLPAAASGDMFVATVKKGK PELRKKVTPAVVIRQRKAIRRKNGVFIFFEDNAGVIVNNKGEMKGSAITGPVAKECADLW PRIASNASSIRKGKTQKVSLGPQVVEGENVFGVAHIYASFNDTFVHVTDLSGKETIVRIT GGMKVKADRDEASPYAAMLAAQDVAEKCKSLGITALHIKLRATGGNRTKTPGPGAQSALR ALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRLMGKPRGLRTARKLKNHRRDQRWADND YKKAHLGTRFKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP RDGCLNYIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKEKKERPR-EST ATLRTRKYMSNRLLSRKQMVVDVLHPGRSTVPKTEIREKLARMYKTTPDVVFAFGFKTKF GGGRTTGFALIYESLDLAKKFEPKYRLARHGSSKQRKELKNRRKKVRGTAKSKIGSMGRV PTIYSKSYTTPRRPYEKERLDQELKLIGEYGLRNKREVWRVKYTLAKIRKAARELLTLDE KDPRRLFEGNALLRRLVRIGVLDEGKMKLDYVLGLRQEDFLERRLQTQVFKLGLAKSIHH ARVLIRQRHIRVRKQVVNIPSYIVRLDSQKHIDFSLKSPFGGGRPGRVKRKNMRK----- ----------------------LLVGASGVGKTLLSKRLQLGDAPSTIPTVGTNLVTLST RKQDVTVRELGGC--MAPIWHKYFENTNRLIFVIDVSNRMQVSTSCIMLLTILKNGNLQN TVFLLVLNKVDSPGCMNRIELNTLMKLDEMAKQHITVLEVSAKEASGLGEVLKWLQD--- ---MPLAKDLLHPSQEVEKRKCKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRRKQHMVRMNVLADALKSIGNAEKRGKRQVLIRPCSKV IVKFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVALRDMENWTSNL LPSRQFGYIVLTTSGGIMDHEEARRKHLGGKILGFFFMGRMHTPGKGISQSALPYRRSVP VWLKLTSEDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKAKGLAAS IPEDLYHLIKKAVAIRKHLERNRKDKDAKFRLILIESRIHRLARYYKLKKVLPPNWKYDS ATASALVAVAELPEIKLFNRWASDDVQVSDISLTDYIAIKEKYSKYVPHSAGRFQVKRFR KAQCPIVERLVNSLMMHGRNNGKKLMAIRIVKHAFEIIHLLTGENPLQVLANAIINSGPR EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREAAFRNIKTIAECLADELINAAK GSSNSYAIKKKDELERVAKSNR-------------------------------------- ---------------------------------------LSGSWDRTLRLWDLFKGVTTR RFVGHTQDVLSVAFSPDNRQIVSGSRDRSIKLWNTLGVCKYTIDDSHDHWVSCVRFSPNT ANPIIVSAGWDRIVKVWNLTNC------------------SPDGSLCASGGKDGMAMLWD LNEGKHLYTLEGGDTINALCFSPNRYWLCAATGPCIKIWDLECKSVVDELRQEVIVSG-- APDCISLAWSSDGQTLFAGYTDNNIRVWQVSMAA-MIEYKLVVLGSGGVGKSALTVQFVQ GIFVEKYDPTIEDSYRKQVEIDGVQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLVYSIT AQSTFNDLHDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKLARQFMCAFMETSAKSK INVNEIFNDLVRQINKKNPEK----KP-GSEHINLKVSGQDGSIVHFKIRKSTPLKKLMQ AYCDRQGVSYKQVRFVFDGNRVNEGDTPSLLEMDDEDTIEVFQQQTGG---LPMNPKPFL NGLTGKPCMVKLKWGMEYKGYLVSVDTYMNLQLANTEEFIDGALTGNLGEVLIRCNNVLY IRGVEDEDEEGEMREMSDAEGDDIPV--GGAGAMDVHTALQEVLKNALIYNGLARGLHEC TKALDKRQAHMCVLANNCNEQAYVKLVEALCAEHGINLLKVDDNKKLGEWAGLCKIDKEG KARKVVGCSCVVVKDYGKDSQATDVLSEYFKSKR------------------------FS RDEFDEIYITTIFETYVADIEVDNMKVELALWDTAGQEDYDRLRPLSYPDTDVILLCFAI DSPDSLVNVKENWLPEIKHFCPHVPYILVGNKKDLRCDAVLISELAKTKQYPIKECDGEL MKELIGAEDYIECSAKTRDGVRETFEAATRAAIHTSKK----MDDFQTGEETAFVVDEVS NIIKESIEGAIGGNAYQHNKVNQWTSNVVEQCLNQLTKLGKPFKYIVTCVIMQKNGAGLH TASSCFWDNSTDGSCTVRWENKTMYCIVSVFGLAIMYSASAKIVKPAGRKPDEFESSISQ ALLDLEMNSDLKAQLRELFITGAKEIDIAGKKAIIIFVPVPQLRAYQKIQTRLVRELEKK FSGKHVVFVAQRRILAKPTRKSTNNSKQKRPRSRTLTSVHDNILEDLCYPAEIVGKRIRI KLDGSRLIKVHLDKNQQTNIEHKLETFTAVYKKLTGKEVVFEFPDYVL------------ ----------------------------KDMKIKTLEEIYLFSLPIKEFEIIDYFLEGRL KDEVLKIMPVQKQTRAGQRTRFKAFVAIGDHDGHVGLGVKCSKEVATAIRGAIILAKLSV IPVRRGYWGNKIGKPHTVPCKVTGKCGSVVVRLIPAPRGTGIVSAPVPKKLLQMSGIEDC YTSARGQTATLGNFAKATFAAIANTYSYLTPDLWKETVFTKSPYQEFTDYLAKMSGGLDV LALKEEDVVKFLACGTHLGATNVDFQMEQYCYKRKPDGTYIINLRKTWEKLLLAARAIAA VENPADVCVLSARPYAQRAVLKYAGATGATAIAGRFTPGTFTNQIQAAFREPRLLVVTDP RTDHQPVIEASYVNIPVIALCNTDSPLRYVDIAIPANNKGSHSIGLMWWLLAREVLRLRG SISREVPWDVMVDLYIYRDPDEVEKEPEVTDWAAEAAAGTAPAPTEDWATETTTDWAAST PQNTWGGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXTPASSTSVGGTVRQRKTASSGGGGAGMWRFYTEDSPG IKVGPVPVLVMSLLFIASVFMLHIWGKYTR-----KKKSAMNEVVTREYTIHIHKRIHGI GFKKRAPRAIREIKKFALKAMGTPDIRIDTRLNKHMWSKGIRNVPFRVRVRLARKRNEDE DSPNRLYTLVTYVPVTTFKGTQTINVDNSGSKEFLINSKYRLLRKIGSGSFGDIYLGLNI ATGEEVAVKLESVKARHPQLLYESKLYKILQGGVGIPHIRWYGERDYSVLVMDLLGPSLE DLFNFCGRRFTMKTVLMLADQMIGRIEYVHNKNFIHRDIKPDNFLMGIGRHCNKVFLIDF GLAKKYRDNRSRAHINYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRGG LPWQGLKAATKKQKYEKISEKKMSTAVESLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLR QLFRILFRTLNHQYDYTFDWTMLKQKASA-MNAQKLSKRMGGKGTPRRKKKTVHRTATTD DKKLQSCLKKLSINPIPGIEEVNMIKDDGTVLHFINPKAQASLTANTFAILGHPELKQIT SMLPGILNQLGSENLTHLRSLAEATDEVD-DDDDVPELVENFDEASKGEXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKKTGPKPELTEE QKQEMREAFDLFDSSGTGTIDTKELKVAMRALGFEPKKEEIRKMIANIDKDATGSIDFTD FISMMTQKMSEKDSKEEILKAFRLFDDDDTGKISFRNLKRVAKELGENLTDEELQEADRD GDGEINEQEFLRIMKKTSLYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMALVIPEKFQHIL RVMNTNIDGRRKIMFAMTAIKGIGRRYANVVLKKADIDLSKRAGELSDDEVERVLTIMSN PRQYKIPDWFLNRQKDIKDGKFSQVMSNALDNKLREDLERMKKIRAHRGLRHYWGLRVRG QHTKTTGRRGRTVGVSKKK-SATDSEDEDSPPELEDFA-AAGVNEEPVSKAKQSRSEKKA RKAMSKLGLKVVFGVTRVTIRKSKNILFVINKPDVFKSPASDTYIVFGEAKIEDLSQQAQ VQAAEKFKADEEVDATGVEEKDIDLVMSQANVSKNRAIKALKNNNNDIVNAIMMGRVRTK TVKKAARVIIEKYYTRLTLDFHTNKRLCEEIAIIPSKKLRNKIAGFVTHLMARIQRGPVR GISIKLQEEERERRDNYVPEVSAIEEVDPDTKEMLKMLDFANIPGLQVTQPIAST----- -------------EKIRKKYPDRVPVIVEKAPKARVGDLDKKKYLVPSDLTVGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGALYQEHHEEDFFLYIAYSDESVYGMREVRIRKL CLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVRSFGIRRNEKIAVHCTVRGPKAE EILERGLKVREYELRRNNFSQTGNFGFGIQEHIDLGIKYDPNIGIYGMDFYIVLGRPGYN VAHKRKKRGVVGYKHKVTKDESMKWFQQKYEGIIMPGKMGIKFLEFVKPFCAVLPEIAKP ERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGIS PIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMVITIGQAIVYVMTGMYGDPAE IGAGVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVN TGRGTEFEGAIIALFHLLATRSDKVRGLREAFYRQNLPNLMNLLATIFVFAIVIYFQGFR VDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYLISQMLAAKFSGNFFVNLLG VWADVGSGGPARSYPVGGLCYYLSPPETLGHVVEDPIHAALYIVFMLGSCAFFSKTWIEV SGSSAKDVAKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIG SGTGILLAVTIIYQYFEIFVKEQSEMGGMSTLLFXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRVIRSQRKGAGS VFRSHTKNRKGAAKLRPVDYAERNGYIKGVVKEILHDPGRGAPLCRVRFRDPYKYRMRTE TFLAAEGMYTGQFVYCGKKAVLQIGNILPVGAMPEGTIVCCLEEKTGDRGRLARASGNYA TVISHNPDTKRSRVKLPSGSKRVIPSANRAMVGIVAGGGRIDKPMLKAGRAYHKYKAKRN CWPKVRGVAMNPVEHPHGGGNHQHIGHASTVRRDTSHGRKVGLIAARRTGRLRGSKKEVE KAKRTKKVGITGKYGTRYGASLRKTIKRMEVTQHGKYTCSFCGKDAMKRQAVGIWHCKGC KKTIAGGAWVQSTNAAATVRSAVRRLREMKEMGRRPARCYRYCKNKPYPKSRFCRGVPDA KIRIYDLGRKKARVDDFPLCVHLVSDEYEQLSSEALEAGRICCNKYLVKMCGKEAFHIRI RLHPFHVLRINKMLSCAGADRLQTGMRGAFGKPQGTVARVNIGQPIMSVRARDNHKEHVI EALRRAKMKFPGRQKIYVSRKWGFTKWDKKDYEEMRADGRLVPDGVVAQYKPHHGPLQAW KNAQRVTKLLGRTGSQGQCTQVRVEFLDDSNRSIIRNVKGPVREGDILTLLESEREARRL RMTKGTSSFGKRHNKTHTLCRRCGRSSYHIQKKKCAQCGYPAAKLRHYNWSEKGKRRKTT GTGRMRHMKRVFRRFRNGFREGTIPKPRKGMVDDKVTAKDLDQSIEQLNECKQLTETQVK TLCEKAKEILSKESNVQDVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDR GYYSVETVTLLVALKVRFPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL FDYLPLTALVDQQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGW GISPRGAGYTFGQDISETFNHTNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRC GNQAAIMELDDALKYSFLQFDPAPRRGEPHVTRRTPDYFLXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXGIAVGRLIEERKCWRKDHPFGFVARPTKQDDGTLNNKEWECAIPGKKGTPWENGLY KLKMIFKDDYPTTPPKCKFDPPLFHPNVYPSGTVCLSLLDEDKDWRPAVTIKQILLGIQD LLNDPNIKDPAQAEAYTIYCQDKNEYERRVRAQAKKFPDTALGKSSKMLQHINYRMRCTL QDGRVFIGTFKAFDKHMNLILGDCDEFRKIKPKNTKQREEKRVLGLVLLRGENLVSMTVE GPPSAEEGIPRVPLPGSGPGPGMGRAAGRGVGQGPGLQGPVRGVGGPSASVMAPQPGM-R GPPPEIVASFKLVLVGDGGVGKTTYVKRHLTGEFEKKYIATLGVEVHPLVFNTSRGCIKF NVWDTAGQEKFGGLRDGYYIQGQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCG NKVDIKERKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLVGDQNLEFTLMPA LLPPDVNMDAKLIEQYENDLKEAQSTLLPEDDED-SEGIRQYYVSKIEDLQLVVTDKTQN LRRLEAQRNELNAKVRMLREELQLLQEQGSYVGEVVKPMDKKKVLVKVHPEGKFVVDIDK NIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEI KEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ KFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRLESGSGGDSEVQRTMLELLNQLD GFEPKQNIKVIMATNRIDILDSALLRPGRIDRKIEFPAPNEEARLDILKIHSRKMNLTRG INLRKIAEMMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFELAVAKVMQKDSEKNMSI KKLWKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMAD CSDLDRQIEQLRRCEIIKESEVKALCARAREILIEESNVQRVDSPVTVCGDIHGQFYDLK ELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQV YGFYDECLRKYGSITVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSITTLDQIRAIDRK QEVPHDGPMCDLLWSDPEDTQGWGVSPRGAGFLFGVDVVAQFNSANDIDLICRAHQLVME GYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFTIFEAAPQDTRGKPQADYFL VRLPPEVNRILYIRNLPYKITTEEMYDIFGKYGAIRQIRVGNTPETKGTAFVVYEDIFDA KNACDHLSGFNVCNRYLVVLYYQSNKAFKKIDTEKKKQDLDSMKAKYGLQTPDKKMSIGV PIKVLHEAEGHIITCETALGEVYRGKLIEAEDNMNCQMQNITVTYRDGRVAQLENVYIRG SKIRFLILPDMLKNAPMFKRVGAGRGKSAILRAAARGRGRGRGG-DRGGXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXMARGPKKHLKRLRAPKHWMLDKLGGTFAPKPSCGPHKSRECLPLCIFLRN RLKYALTYDETQKIVMQRLVKIDGKVRTDKTYPTGYMDVISIEKTNEYFRLIYDVKGRFA VHRITAEESKYKLCKVKKVGVAPKGVPFIVTHDGRTIRYQDPLIKVNDTVQLMGTKDDEY DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTA GQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADNNIVIMLVGNKCDL RHLRAVPTEEAKAFAEKNNLSFIETSALDSTNVETAFQNILTEIYRIVSQKPL-PSADDS NVQTIRVEPTENMNERKKIFCC----YGFSLTTFSPSGKLVQIEYALAAVAAGAPSVGIK ATNGVVLATEKKQKSILYDEHSIHKIEMITKNIGMVYSGMGPDFRVLTLAARKLAQQYYL AYHEQIPTVQLVQRVAHVMQEYTQQGGVRPFGVSLLLAGWDKRPYLYQCDPSGAYFAWKA TAMGRNFVNGKTFLEKRYSETLE--ED--------------------------------- ---------------------------AGGNQGDKKDDKDKKKKYEPPIPTRVGKKKKRI KGPEAANKLPLVTPHTRCRLKLLKLERIKDYLLLEEEFIKNQERLKPQEEKNEEERSKVD DLRGTPMSVGNLEEIIDDNHAIVSTAVGSEHYVSILSFVDKDQLEPGCSVLLNHKVHAVV GVLSDDTDPMVTVMKLDKAPQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIRPPK GVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPS IVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPA LIRPGRIDRKIEFPLPDEKTKRRIFNIHTNRMTLAEDVKIEDYVMAKDDLSGADIKAICT EAGLLALRERRMKVTNEDFKKAKENVLYRKNEGTPEGLYLKKRPYSPFQNSNVAEYALAR ADDLLNWARKSSLWPLTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQADCIIVAGTL TNKMAPAFRKVYDQMPEPRWVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPS AEALLYGILQLQKKIKRMNNVQMWY--GDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYA NNSNYKNDTMIRKEAYVHRSVMEELKRIIEDAEIMQENDSLWPQPDRVGRQELEIVIGDE HISFTTSKIGSLVDVHQSKDPEGLRTFYYLVQDLKCLVFSLIGLHFKIKPIMAPTKKSKK SIESINSRLALVMKSGKYVLGYKQTLKTLRQGKAKLVIIANNTPPLRKSEIEYYAMLAKT GVHHYNGNNIDLGTSCGKYFRVCVLSITDPGDSDIIRSMPSGMTEYKLVVVGAGGVGKSA LTIQLIQNHFVEEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGF LCVFAVNNTKSFEDISQYREQIKRVKDMDEVPMVLVGNKVDLPTRTVDTNQAHQIADSYH IPYVETSAKTRQGVDDAFYTLVREIRK-MGDRYNIHSQLEHLQSKYIGTGHADTTKWEWL TNQHRDSNASYLGHFDLINYFALAENETKARIKFTLMEKMLQPCGPPPERPEDMKIELCA FSGFKIYPGHGKRMIRLDGKSYTFINGKCQKSHVMKRNPRKINWTVLYRRKHKKGLQEET TKKRTRRTVKFHRAIAGATLSDIMAKRNQKPEVRKAQREQAIRAAKEKNKAKTAKAPRVG GKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKVKAKEL RGKKKEELLKQLDEHKQELANLRVAKVTGGAASKLSKIRVMRKSIARVYTVIHQTQKENL RKYYKPKDLRKKLTRAMRKALSPHEKSLKTQKQLRKMRAFPMRKFAVKGAANGPKVTEKV YFDITIGGEPAGKIVIGLFGKTVPKTAENFATLAEGKKTYVDSKFHRVIKDFMIQGGDFT RGDGTGGRSIYFADENFKLKHYGAGWLSMANSGADTNGSQFFITTVKTKWLDGRHVVFGK VLEGMSVVRKIEQSKTGNDRPEKDVVISASGRMKVEKPFSVEKKGADEKKKKISLKFTID CTLPVEDGIMDAANYEKYLHERIKVTGKTNNLKSKIIVNCEVPFSKRYLKYLTKKYLKKN NLRDWLRVVANDKESYELRYFQINNEEEDEDE--TKDEKGEEEKVYGGCEGPDAMYVKLV SSDKHEFIVKREHALTSGTIKAMLSGPGQFAENETNEINFREIPSHVLQKVCMYFTYKVR YTNSSTEIPEFPIAPEIALELLMAANFLDC-------EVGKHCSMDSCWIIVHDKVYNVT EFVSKHPGGVEIILESAGYDATIPFKYKGHSDHAYEMLEKYLIGIIVENER--------- --------------MSYMLPHLHNGWQVDQAILSEEERTVIIRFGHDWDPTCMVMDETLY KCANKMKNFAVIYLVDITEVPDFNKMYELYDPCTVMFFYRNKHIMIDLGTGNNNKINWPM TDAQEFIDIIETVYRGARKGRGLVVSPKDYSTKYRYKKLQRQLEFLEVQEEYIKDEQKNL KKEYLHAQEEVKRIQSVPLVIGQFLEAVDQNTGIVGSTTGSNYYVRILSTIDRELLKPSA SVALHKHSNALVDVLPPEADSSITMLQSDEKPDVTYGDIGGMDIQKQEVREAVELPLTHF DLYSQIGIEPPRGVLMFGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVR DVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTINVKVI MATNRADTLDPALLRPGRLDRKIEFPMPDRRQKRLIFSTITGKMNLSEEVDLEDYVARPD KISGADINAIVQEAGMQAVRENRYVVLAKDFEKGYKNNIKKDEQEHEFYKSHVPLTLEMI RERVLLVLKLYDKVNPEKLTVDSHFINDLGLDSLDTVEVIMAMEDEFGFEIPDNDAERLL KPADVIQYIADKEDVSRRV--MNDDLKNVEFETSEDVEVIPTFDSMSLREELIRGIYAYG FEKPSAIQQRSIRPIVKGKDVIAQAQSGTGKTATFSISVLQCLDTQVRETQALVLSPTRE LAKQIQKVVLALGDYMNVQCHACIGGTNVGEDMRKLDYGQHVVSGTPGRVFDMIRRRSLR TRSIKMLILDEADEMLNKGFKEQIYDVYRYLPPATQVILISATLPHDILEMTSKFMTDPI RILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTDKM REANFTVTSMHGDMPQKEREEIMKEFRSGASRVLITTDVWARGLDVQQVSLVINYDLPNN RELYIHRIGRSGRFGRKGVAINFVKTDDIRILRDIEQYYSTQIDEMPMNVADLI------ ----------------------------------------------------AQLPRIGI GMDSCVVPLRQPNLSLVQTTDFFYPLVDDPYMMGKIACANVLSDLYAMGAMDCDNMLMLL GVSQKMSDKERDVVVPLIMRGFKDTAEEAGTAVTGGQTVLNPWLTIGGVATSVCQSNEFI MPDDAVAGDVLVLTKPLGTQVAVNAHQWLDVPEKWNRLKLVVSEEDVRKAYHRAMTSMAR LNRTAAKLMHKYSAHGATDVTGFGLLGHANNLARIQKREVSFVIHNLPVIAKMAAVSKAC GTTFGLYQGMSAETSGGLLIALPREQAAAFCKDIERQEGYQAWIIGIVERGNHTARIIEK PRVIEVPAKEKDILVSMLKSAHGYFIGVDANAEECFFDRVKSGTKLSLMFEVAEGGFLDI DVKIIGPDSKVIYTGDRESNGKYTFAAHMDGLYKYCFSNKMSTMTPKVIMFTMDIGEKPK AHQNKLEEMINELSTALTGVKHEQEYMEVRERIHRSINDNTNSRVVLWSFFEALVLVAMT LGQIYYLKRFFEVRRVVMAATLKPYLNAVRHTLTAAMCLENFSSQVVERHNKPEVEVRSS KELLLTPVMISRNEKEKVLIEGSINSLRISIAIKQADELERILCKKFMRFMMMRAESFVV LRRKPIEGYDISFLITNFHTEQMYKHKLVDFIINFMEEIDKEISNMKLAINARARISAEE FLKHFSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLV TMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTMPNSFKTLDSWRDEFLIQASPRDPDN FPFVVIGNKIDLENRAVSTKRATSWCSSKGDIPYFETSAKEAINVEQAFQTVAKNALAQE TEVELYNEFPEQIKLS----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPDHLGADQRKVRDEEKDDKPIQVLD EGDIALLKTYGAGQYSKLVKAAEEDIQSYLKKVNELAGIKESDTGLAPPALWDLAADKQT LQSEQPLQVARCTKIINADSDDPKYIINVKQFAKFVVDLGDQVAPTDIEEGMRVGVDRNK YQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIDKLREVVETPLLHPERFVKLGI EPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMART KKACIVFFDEIDAIGGCRFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDT LDPALMRPGRLDRKVEFGLPDLEGRSHIFKIHARSMSVEKDIRYELLARLCPNSTGAEIR SVCTEAGMFAIRARRKMATEKDFLEAVNKVIKAYAKFSATPRYMTYN------------- ------------------------------------------------------------ DIALWKFETKNFYVTIIDAPGHRDFIKNMITGTSQADCAVLIVASSTGEFEAGISKEGQT REHALLCYTLG----------------------------EVSAYIKKVGYNPKTVAMVPI SGWVGDNMINMSWYKGWEIAKGKTLLEALDAIVPPTRPTDKPLRLPLQDVYKIGGIGTVP VGRIETGTLKAGMVVTFAPAGVTTEVKSVEMHHETLEVGNPGDNVGFNVKNVSVKDIKRG NVAGDSKSDPPKETRCFNAQVIVLNHPGQIHAGYAPVLDCHTAHIACKFNELKEKCDRRS GKKLEDNPKFVKNGDAAIVELVPSKPMCVEAFSEYPPLGRFACRDMKQTVAVGVIKSVEK KD-KADKVTKSAAKAELDQLRQECEQLKNQIREARKAAADTTLGQATQNVEPVGRIQMRT RRTLRGHLAKIYAMHWATDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAP SGSFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIVTSSGDMTCA LWDIETGQQTTSFTGHTGDVMSLSLSPDYRAFVSGACDASAKLWDVRDGMCKQTFSGHES DINAITYFPNGYAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLG GYDDFNCNVWDTLKQDRAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKIWN------- ------------------------------------------------------------ -------YYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLEARR DVKKEEGEAFAREHGLIFMETSAKTAANVEEAFINTAKEIYQKIQDGVFDINNEANGIKI GPQHSPTNPSSGGGGNQAGG---------------------------------------- --------------VVGAVCCRVDTADNQRRLYIMTLGCLAPYRRYGIGTEMLIHVLNIC EKDGNYDNVFLHVQINNDGAIAFYEKFGFEIV------------------------MPRQ INEIKDFLLTARRKDAKSVKIKKNVKFKVRCSRFLYTLVIQDREKAEKLKQSLPPGLAVK ELK----NXXTVFEAVDAVLEKKRKFTETVELQIALKNYDPQKDKRFSGTVKLKKVPRPN MKICVLGDAQHMDEATANDVPCMDAEGLKKLNKNKKLVKKLAKKYDAFLASDSLIKQIPR ILGPGLNKAGKFPTMLTHNESMTGKIEEVKATIKFQMKKVLCLAVAIGNVKMTREELAGN IQLGVNFLVSLLKKNWQNVRALYIKNTMGPSIRIYMADADKLNIDSIIARLLEVRGSRPG KNVQLTEAEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL WSDPDKDTTGWGENDRGVSFTFGAEIVGKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFTYGGLNSGRPVTPPRGQAKNK KK-MFKNTFQSGFLSILYSVGSKPLQIWDKVVRNGHIKRITDNDIQSLVLDISGTNVSTT FIKCPADPHKNLGIKLPFLVMIIKNLKKYFTFEVTVLDDKKVRRRFRASNYQSTTRVKPF ICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLQVQIHANCRIRRVYFSDRLYSEDEL PAEFKLYLPLQ-------IQNLKDPFADVQ-VHVRIQQRNGRKTLTTVQGLHEKFDKKLI AKYCKKHFACNGTVVEHPEYGEVIQLQGDQRDAFVEFLKSTGMPEAIKVHGFSALFNFQS LLTVVLLLICTCAYLRSIAPSILDKNKEGLLGIFWKSARIGERKSPYVAVCCIAMAFSIL FLSSSRLTAAVARQLPQIGSKKNGMGAGFVAFKKFTTSPEVSQILEERIMGASKVDLEET GRVLSIGDGIARVYGLKNIQAEEMVEFSSGLKGMALNLEPDNVGVVVFGNDKLIKEGDIV KRTGAIVDVPIGEEILGRVVDALGNPIDGKGPLGNKTRARVGLKAPGIIPRTSVKEPMQT GIKAVDSLVPIGRGQRELIIGDRQTGKTAVAIDTIINQKRFNETQDEKKKLYCIYVAIGQ KRSTVAQLVKRLGDADALKYTIIVSATASDAAPLQYLAPYSGCAMGEYFRDNGKHALIIY DDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDDFGGGSLTALPVIE TQAGDVSAYIPTNVISITDGQIFLETELFFKGIRPAINVGLSVSRVGSAAQTKAMKQVAG SMKLELAQYREVAAFAQFGSDLDQATQNLLNRGVRLTELLKQGQYVPMAIEEQVAVIYAG VRGHLDKVEPAKITQFEEEFVKHIRSTQQDLLKSIREEGKISEANDAKMKALVQDFVASF MESLYSIPFRVLECPNLKIKRPSWVKVPSAMFVFALILGSYFLVTGGIIYDVIVEPPSIG STTDERGNSKPVAFMPYRINGQYIMEGLASSFLFTIGGLGFIILDQTNKAGTPKLNRILL LSVGFICILVSFFMCRVFMRMKLPMPKVRKSRKPPPDGWELIEPTLDELDQKMREAEIDP HEGKRKVEGLWPIFRIHHQKSRYIYDLYYKRRAISRELYDYCLKEGIADKNLIAKWKKQG YENLCCLRCIQARDTNFGTNCICRVPKAKLEEGKIVECIHCGCRGCSGEYAQVIRMLGNG RLEALCFDAVKRLCHIRGKLRKKVWISPQDIILVGLRDYQDNKADVILKYTPDEARNLQS YGEIPETAVISHDF-GNVVFGELDD-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--MQK PKSEMSPEELAAQEQEEFNTGPLSVLTQSVKNNTQVLINCRNNKKLLGRVKAFDRHCNMV LENVKEMWTEYPRTGKGKKKSKPVNKDRFISKMFLRGDSVILVLRNPLPLVIDARGHLLG RLAAIVAKSILQGQRIVVVRCEGINISGSFYRNKLKYLEFLRKRCNVNPAHGPYHFRAPS KIFWRTVRGMLPHKLSRGKEAMDRLKVFEGIPPPYDKEKRMVVPSALKVLRLNPRRKFCV LGRLSHEVGWKYQTVIATLEKKRKLKSKQYYTQKKRETVLKNKARKVEPYQKIMESYG-A GDPIKGAKVFKQRCDQCHTVEKGGKHKTGPNLHGLLGRKTGQAPGFSYTDANKNKGITWS RDTLWVYLENPKKYIPGTKMIFAGLKKKNERADLIAYLEQSTK--LQLTLALLKPDLVIQ GIHDRILQNNFLFVRSKVLKLSQERAAEFYKEHTGKFFHNRLVLYMSSGPLYAHILARED AIAEWRKLMGPTKVFRTLYEQPNTLRGLYGLTDTRNGTHGSDSAESAKKEINFFFP---- -------------------------------------------------------MFEAK IEKGVWWKKIVESVKDIVTNGIFDCSETGISLQCMDSSHICLVNLLLRCDGFDDFRCDRN VALGLNLESLGKLMKCANNDDAVTLKAGENSDNLTLMFESPNKEKVSDYEMKLIDIDQEH LGIPDTDYTCVVRMPSAEFQRICRDLSQIGDTVVISCTKEGIKFTSSGDLGTGNITLAQH ASADKGDE-VSIEIKEAIVLNFSLRYLNFFTKATSLSPFITLSMAPGVPLVVEYKIEDLG HIRYYLAPKLDDED--SAISAYHSSTGLPEGKIVAVIGAVVDVQFEEDLPPILNALEVEN RSPRLVLEVAQHLGENTVRTIAMDGTEGLVRGNVCKDTGTSISIPVGPETLGRIMNVIGE PIDERGPIPTDKRASIHQDAPEFVDMSVQQEILVTGIKVVDLLAPYAKGGKIGLFGGAGV GKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVISLKDDSSKVSLVYG QMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVG YQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDANTVLSRAIS ELGIYPAVDPLDSNSRILDKNIVGEEHYNIARGVQKILQDHRSLQDIIAILGMDELSEED KLTVSRARKIQRFLSQPFQVAEVFTGSPGKLVPLADTIKGFKMILSGELDHLPEVAFYMI GPIEEAVAKAERLAEE-MLMPKKNRVLIYEHLFKEGVMVAKKDFNAPKHPEIEVPNLQVI KSLVSLRSRGYVKEQFAWRHYYWYLTNEGIQYLRDYLHLPPEIVPSTLKRQEPRGDRDSY RRTGGADKKADVGAGAS-----------------QHTEFTEEEIQDWYKGFLKDCPSGNL TVEEFKKIYGNFFPYGDASKFAEHVFRTFDTNSDGSIDFREFICALSVTSRGDLEAKLKW AFNMYDLDGNGYISRTEMLEIVRAIYKMVGTVMKMPEDESTPEKRTDKIFRQMDKNLDGK LSLAEFIEGAKSDPSIVRLLQCDP---SEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNL TGLNEQVPHYRQALDMILDLEPDDELEDNPNQSDLIEQAAEMLYGLIHARYIMTNRGIAQ MIEKWQQGDFGYCPRVYCENQMTLPIGLSDVPGEAMVKLYCPRCQDVYTPKSTRHHHTDG AYFGTGFPHMLFMVHPEYRPKRPNNNFV-------------------------------- MTNPKGYRRGTRHMFSRKFRTKGYIPLSTYMKVYKRGDIVDIKANGAVQKGMPHKVYHGR TGKVYNVTPHALGVIVNKRVKGRILPKRINVRVEHVKHSNCRLDFLKRVKENERIKKEAK EQADFKRKPVGPREAHFVRTKFNKPQVIEPIPYEFIA-----YVLVAPKEPSMEWSDLSD RAATSVFWTELARGFGITASMLFKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIA CKLCEAICPAQAITIEAEPRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEF STERHEELLYNKEKLLNNGDKWEPEIAANLVADHLYR------------------DAETQ KALEDIDSCQNEIDALNEKASEEILTVEQKYNKLRKPHFDKRNELIQKIPNFWVTAFVNH PQISAILDEEEEECLHYLNKVEVEEFEDIKSGYRIKFHFAQNLFFENEVLCKEFHLAASQ SSPIKWKQGMDLTKKARKRKYGSSRSFFVWYLDNSDPSVDDIAEVIKDDMWPNPLQYFLA PDIEVEENDDD------KKLTREEELLLQDFSRNVTTKSSALFYGNAFIVSAIPIWLFWR IHQMDPY----------------------------------EAVTREVMKSIGDDKKMSK KEKDERILWKKNEVADYEATTYSIFYNNAFYLLLMILLSFYVLRSFSPMFNYILSVGVAS GLIALFSTSTKATQGKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQT VCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNHETFGRAKTWVKELQRQ ASPNIVIALAGNKADLRMVEYEDAQSYAEDNSLLFMETSAKTAMNVNDLFLAIAKKLPKN ETNVNLEEP-MAEYLASIFGTEKDKVNCSFYFKIGACRHGERCSRLHNKPTFSQTILIPN LYINPQNSALIQVTEVEMQQHYDEFFEEVFVELEDKYGEIEEMNVCDNLGDHLVGCVYVK FRYEEDAEKAVADLNNRWFNGRPIHAELSPVTDFREACC------------LCNFMHLKP ISRELRRELYGRHKRSRSRSPPTRHSGSRSRRDHRRRSNSRDRR-MFLTRSEYDRGVNLF SPEGRIFQVEYAIEAIKLGSTAIGIQTSEGVVLAVEKRVTSPLIEPSSIEKIFEIDSHIG CAMSGLIADSRTMIDKARVEAQNHWFTYNEKMSVESVTQAVSNLALAFGDDNAEAGALSR PFGVALLFAGIDKQKPQLFHVDPSGTFIQYDAKAIGSGSEGAQQALQEVYHKSMTLKEAC KHALTILKQVMEEKLNSTNVEMATITQEKNFCMCTKEQLEEVIKDIALKTWEMSNNIDNV NSVEDIYRFDKKQQQDILTAKPWDKDPHYFKYIKISALALLKMVMHSRSGGNLEVMGLLL GKVDGNVMIVMDSFALPVEGTETRVNAQAQAYEYMAAYTEAAKQVGRLENVIGWYHSHPG YGCWLSGIDVSTQMLNQQFQEPFVAVVIDPVRTISAGKVNLGAFRTYPKGYKPPDEGPSE YQSIPLNKIEDFGVHCKQYYSLEVSCFKSALDRRLLESLWNKYWVNTLSSSSLLTNAEYM TGQIFDLADKLEQSEAQLGRGGFMDKKTEDKLAKTTKDACKTTIEAIHGLMSQVIKDKLF NKL-GLPRRITKETQRLMTEPVPGIQATPDEENGRLFYVVMDGPKDSPYETGTFKLELFL PEDYPMAAPKVRFLTRIYHPNVDNLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPD DPLNNAVAEVWMENELKAIELAREETRLYADVENELLDYEE-EDQETKDVKGTYVSIHSS GFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILAMDVLTQAKSGMGKTAVFVLATLQ QLEPVDNQVSVLVLCHTRELAFQISKEYERFSKYMNNIKIAVFFGGISIKKDEEVLKKNC PHIVVGTPGRVLALCKVLNLKHLKHFILDECDKMLEALDMRGDVQEIFRMTPHEKQVMMF SATLSKDIRPVCKKFMQD------------------------------------------ --------------------------------------------KLKSFQCRVLISTDLI SRGIDAERVNLVVNLDMPRDHETYLHRIGRAGRFGSYGAAVSLVAEGVEMNLPPCYGDLG KSGRDLFNKGYNYGFHKMEVKTQASNGMQFTVGGNSNSDTGKIAGNLETKYKWSDYGLTF TEKWNTENVLATEVTIEDQIAKGLKLSFDTSFAPHSGKKSGKIKTAYKMDYLHANCDVDF DFAGPTIHGAAVLGYNGWLAGYQMSFDKSKLTRNNFAVGFSGDDFTLHTSVTDSSEFAGS IHQKVNKNLETGVNLSWTAGTNATRFGFAGKYKLDDDTFVRMKVNNAGQIGMGYATNIRD GVQLTLSTLIDAKNINAGGHKIGLGLDID-DTVREKALTDYRKKLLEHKELEARLKEMRE QLKDLTKQYDKSENDLKALQSVGQIVGEVLKQLTEDKFIVKATNGPRYVVGCRRQIDKAK LKPGTRVALDMTTLTIMRYLPREVDPLVYNMSSEDPGDISYSQVGGLGEQIRELREVIEL PLLNPELFQRVGITPPKGCLLYGPPGTGKTLLARAVASQLEANFLKVVSSAIVDKYIGES ARLIREMFGYARDHQPCIIFMDEIDAIRRFSEGTSADREIQRTLMELLNQMDGFDALGQV KMIMATNRPDTLDPALLRPGRLDRKIEIPLPNEQARMDILKIHAAPIAKHGEIDWEAVVK LSDDFNGADLRNVCTEAGMFAIRSERDYVIDEDFMKAVRKVSDNKKLESKLDYKPVMPES IFSVVGKFYDEYMNNTSKKLKIIDSYLFYVMLTGIVQFVYCLLVGTFPFNSFLSGFISCV GTFVLGVCLRLQVNPQNKHDFHGLSPERAFADFIFAHVVLHLVIINFIGSLATPAQLLPL ELVDKCIGSKIHIIMKNDKEITGILLGFDDYVNMVLEDVTEFESTPEGRLITKLDQILLN GNNITMLVPGGDGPEVIDHYENPRNVGSLDKKSKKVGTGLVGAPACGDVMKLQIEVDDNG KIVDAKFKTFGCGSAIASSSLATEWVKGKSLDDAGRVKNSDIAKELCLPPVKLHCSMLAE DAIRAALNDYKLKN-MLVLVLGDLHIPHRCNSVPAKFKKLLVPGKIQHILCTGNLCTKES YDYLKTLASDVHVVRGDFDENMNYPEQKVVTVGQFRIGLCHGHQVVPWGDNESLAMIQRQ LDVDILISGHTHKFEAFEHENKFFINPGSATGAYNALDTNVMPSFVLLDIQQLTVVCYVY QLIGEEVKVERIEYRK-------------------------------------------- ---RYPRRVTKKMSKKKIKQRSKVKAFVKVYNFNHLMPTRYSVVPMEKQTVNKDAFRDPA LKRKAVREVKGKFEERYKTGKNKWFFQKLRFERTFIMVKPDGVQRGLVGEIITRFEKKGY KLVAMKFMKANEDLLRKHYAEHVEKSFFKRLLAYMLSGPVVPMVWEGDVVISARKMMGAT NPKDSAPGTIRGDLALDMGRNVIHGSDAVETAKTEMGLWFTDKELVSHDAALHSWLYEXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPSKQRMRVANDKHSKNVGQKGNVPKTLKQ NEDKYPVGPWLIALFVFIVCGSAIFQIIQSIRMIDVKSWTAVATWRWVANDENCGICRMP FDGCCPDCKLPGDDCPLVWGQCSHCFHIHCIVKWLNSQQVNQQCPMCRQEWKFKEMIRFI LIQNRAGKTRLAKWYMHFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIVYRRYAGL YFCICVDVSDNNLVYLEAIHNFVEVLNEFFHNVCELDLVFNFYKVYSVVDEMFLAGEIRE TSQTKVLKQLLMLTSLEEPTIFDKIIDGSIKADIIYRDDECLAFRDVNPQAPVHFLVIPL KRIPMLSEDKSLLGHLLLVAKKVAAQSNGFRININNGKDGAQSVNHLHVHVLGGRQMGWP PMGGIWSLFSSLWGSNERRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVTYKN IKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSMDKDRIGISKQELVSMLEEDELKKAI LVVLANKQDLQGAMTASEVANSLGLPAIKNRRYQIFKTSALKGEGLDDAMEWLSTAITSQ K----------------------------------------------------------- ----RTYAAEGRFTFTSHSSGEHQVCLHSNSTAWFGGGQLRVHLDVQVGEHANDYQQIAA KDKLTELQLRVRQLLDQVDQITKEQNYQRYREERFRQTSESTNQRVLWWSIAQTVILLIT GLWQMRHLKGFFEAKKLVMFYHVSLEHEILLHPRYFGPNLLNTVKQKLFTEVEGTCTGKY GFVIAVTTIDNIGAGYIQPGRGFVLYPVKYKAIVFRPFKGEVLDAVVTQVNKVGLFTEIG PLSCFISKHSIPPDMEFDSNSNPPCYKTKEEDVVIQPDDEIRLKIVGTRVDANDIFAIGS LMDDYLGLVSRLYCKAVFTGYKRGLRNQHENTALLKIEGVIKKEHTPFYMGKKCAYVYKA KNKTTCPGHDKTSRIRVIWGKITRPHGNSGAVRAKFARNLPAKAMGRRIRVMLYMAKKTY DLLFKLLLIGDSGVGKTCLLFRFSDDAFNTTFISTIGIDFKIKTVELGGKKIKLQIWDTA GQERFHTITTSYYRGAMGIMLVYDITNDKTFDNISKWLRNIEEHANEDVEKMILGNKCDM DEKRRVPKERGTLIAREHNIPFLETSAKSNINVEKAFMDLAQAILNKXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXMAARPLISVYSDKNEATDSNIMLPAVFRAPIRPDIVNFVHFQMLKNTRQPYAV SKDAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTYRRWHRR ININQRRYAMCSAIAA---------------------------IEEIKRTKEAVKVLKSF KAWADIEKVYKSKRFRAGKGKMRNRRRIQKRGPLVIYNQDNGICRAFRNIPGITLINVNR LNLLKIAPGGHVGRFCIWTESAFKRLDKLYGTWKTPSKEKTDYNLPMPKMTNSDLARLLK SDEIKSALRPRKSRVQRKVLKKNPLKNIRTMIRLNPYASVQKRHAIQRKNRQLEIMKKRG AAPTEPKKKSAAAKRAAGSGEQELATKMLQIQSKRFYLDVKQNKRGRFIKIAEVGANGRK SRLLLAMSTAAEFRDHLTEFNEHYVNLGPQSTES-EKDGKLKSEIMKKDNRRYYLDLKEN QRGRFLRVSPRTNHRIQIAIPAQGLIEFRNALTDLLFDFGTDDHEGQPDLPASRSMRVEN KIFYFDVGTNRRGVFMRISEANFRTAITIPEKSWEKFRDIMTDFVE-QDRKLRDAQMRAT INQKLIETGERERLKELLRTRLIECGWRDQLKAYCKEIVRQKGLEHITVDDLVTEITPKG RALVPDQVKKELLQKIRTFLAQQSNMNIRNACPEDLMNMQHCNLLCLPENYQMKYYFYHG LSWPQLSYVAEDESGKIVGYVLAKMEEDPEDSVPHGHITSLAVKRSHRRLGLAQKLMDQA SRAMVESFRAKYVSLHVRKSNRAALHLYTSTLKFSISEIEPKYYADGEDAYAMRRDLSEF LDKYMSHTILLVQPTRRPESRTYSDYENVNDCLEGVCKIFEEHLKRMNPSSPSITYDISQ LFDFIDQLADICCLVFQKGKATYVPHNKEWIKERIYVLLRKQAGEMAEPQEDKK-EETKA RVHTYPLIRHSDMPEEMRVEAMELCVTACEKFASNNENAAKMIKETMDKKFGASWHVVVG EGYGFEITHEVKNLLYMFFAGTMSIILWKCSMSHRKFSAPRHGSLAFLPKKRSRRHRGKC KSFPKDNKTQPCHLTAFLGYKAGMTHVVREADRPGSKLNKKEIVEAVTIVETPPMIAVGV VGYIETPKGLRTFKTVFAEHLSEECRRRFYKNWYRCKKKAFTNYAKKWQDKVGKKDIARD FAKMKKYCKVIRVIAHSQMKLLKKRQKKAHIMEIQVNGGTIPKKVDFARRLMEKSIPVNQ VFSPDEMIDVIGVTKGKGYKGVTSRWHTKKLPRKTHKGLRKVACIGAWHPSRVQFSVARA GQKGYHHRTEINKKIYRIGAGIHTKGGKVIKNNASTEYDITEKTITPLGGFPHYGEVNND YLMIRGALVGPKKRVLTLRKSLLVHTKRVALEKIKLKFIDTSSKFGHGRFQTREEKIAFM GPMKKDMQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLG LWDTAGQEDYDRLRPLSYPQTDVFLICFSLISPASFENVRAKWFPEVSHHCPNTPIILVG TKLDLREDKETNDKLKEKRLAPITYPQGLSMAKEVHAVKYLECSALTQKGLKMVFDEAIR AVLVPPQKKPNRKKCQIL------KKKKKKKMTFDPNLIVDDLNLDE-KTKKKKKAKKKF DMDDMKEAVEEAEKGFKGEKKKANTDRDYTYDELLQRVFDIMREKNPDILAGEKKRLVMK PPQVMRVGTRRTAFVNFTELCKMLHRQPKHLLAFLLAELGTSGSVDGNNQLIIKGRFQAK QIENVLRRYIKEYVTCHTCRSPDTILQKDTRLFFLQCETCGSRCSVASIKSGFQAVTGKR AAIRAKTT---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------------DKTVA LWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQSAEDA EDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEEPETPAS ELEMPHPSRARVYADVNSHRARSYWEYESHVVEWGQQDDYQIVRKLGRGKYSEVFEAINI TNNDKCVIKILKPVKKKKIKREIKILENLRGGTNIISLCAVVKDPVSRTPALIFEHVNNT DFKQLYQTLTDYDIRFYLFELLKALDYCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLA EFYHPGQEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPFFHGHDNY DQLVRIAKVLGTEELYEYVEKYQIEMDSRFNDILGRHSRKRWERFVHSENQHLVSPEALD YLDKLLRYDHAERLTAREAMEHSYFYPIVKEQPPESLLKARKFKAAAYKEKRHLIFKRAE SYIKEYRTREREEIRLARQARKEGNFYVPAESKVAFVMRIRGINGVHPKPRKVMQLFRLR QINNGVFIRLNKATINMLRLAEPFITWGYANLKSVRELIYKRGYGKVDGRRVPLTDNSII EKNLGRCGIICMEDLIHEIFTCGPNFKKASNFLWPFKLNTPTGGWRKKNNHFVDGGDFGN REDYINALLKRMMQFMLLFSRQGKLRLQKWYNAVTDRVKKKTTRELISLVLARKPKMCSF IEWKDLKIVYKRYASLYFCCAVENSDNELLTLEIIHRYVELLDKYFGSVCELDIIFNFEK AYFMLDEYLLGGEVQESSKKNVLKAIAAQDQLQEEEPRSLLEEMGLGMSKAHPPELKKYM DKRLTLKLNGYRQITGVLRGFDPFMNIVIDECIEELKTGEKRPIGMVVVRGNSVVLLESQ ERIEFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTI RLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFQQTSKWIDDVRTERGSDVIIM LVGNKTDLSDKRQVSTEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMEQTDQ KKMIEVKLKDTPSE---MAVRYQMAVGLEKGHKVTTTKTRPSRRKGRLTKHNKFIRDLVR EIVGFAPYERRCIELLRVSRDKRALKFVKKRLGTHLRGKKKREEMQSVIQQMRKAMVDEA TKKTLAKIPMLKTKAGPRDKELWIQRLKEEYHCLIKYVHNNKEADNDWFRLESNKEGTRW FGKCWMIHQLLKYEFEIEFDIPITYPTTAPEIAIPELDGKTAKMYRGGKICLTDHFKPLW ARNVPKFGIGHAMALGLGPWLAVEIPDLIEKGIVVHKS----FDFLDDVRRMNKRQLYYQ VLNFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLLLTNYEEEPIRVGD IVVFKVEGRDIPIVHRVLKVHEKENGEVKFLTKGDNNSVDDRGLYAPGQLWLRKKDVVGR ARGFLPYVGIITILMNDYPKFKYAILALLGVFVLIHREMSTMNPEYDYLFKLLLIGDSGV GKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYR GAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEY ADQLGVPFLETSAKNATNVEQAFMTMAAEIKNRMGPVTPSPNVKINSSTPVKQSGGGCCE ESLGEDILRMSTDEIVSRTRLLDNEIKIMKSEVMRISHELQAQKEKIKENTEKIKINKTL PYLVSNVIELLDVDPQDMGEEDGANVDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKL HPGDLVGVNKDSYLILETLPAEFDSRVKAMEVDERPTEQYSDIGGLDKQIQELIEAVVLP MTHKERFEALGIQPPKGVLLYGPPGTGKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGA KLVRDAFALAKEKAPAIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFAPSSD IKVIAATNRVDILDPALLRSGRLDRKIEFPSPNEDARARIMQIHSRKMNVSKDVNYEELA RCTDDFNGAMCKAVCVEAGMIALRREATELSHEDYMDAILEVQAKKKANLNYYAKDAADQ NFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRQDKRVKLQIWD TAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDNAQVVLVGNKC DLEDERVVSTERGKQLADQLGLEFFETSAKENINVKAVFERLVDIICDKMSESLDSDPTK GTRLTENPNQQNSGCQCRRSHHLAVSRDYISQPRLTYKTVSGVNGPLVILDDVKFPKYAE IVDITLADGSVRSGQVLEVSGSKAVVQVFEGTSGIDAKYTSCEFTGDILRVPVSEDMLGR VFNGSGKPIDKGPSVLAEDFLDIQGQPINPWSRIYPEEMIQTGISAIDTMNSIARGQKIP IFSAAGLPHNEIAAQICRQGGLVKLPTKSVMDDHDDNFAIVFAAMGVNMEIARFFKQDFE ENGSMENVSLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALRE VSAAREEVPGRRGFPGYMYTDLATIYERAGRVQGRNGSITQIPILTMPNDDITHPIPDLT GYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEDMTREDHSDVSNQLYACYAIG KDVQAMKAVVGEEALSPDDLLYLEFLTKFEKNFISQGHYENRTIFESLDIGWQLLRIFPK EMLKRIPEKTLAKYYPRD--GPGFVGIKFCQECNNMLYPKEDKENKILLYACRNCDFQME ADNPCIYVNKIQHDVDELTQIVADVIADPTLPRTEDHPCPKCGHREAVFFQSSSTKAEEG MRLYYVCTLSKCAHRWTE--RYKVADISLAPQGRLAIEIAENEMPGLMSLRKKYGKEKPL KGARIAGCLHMTVQTAVLIETLTELGAEVQWSSCNIFSTNDIAAAAIAATGVPVYAWKGE TDEEYMWCIEQTLVFKDGQPLNMILDDGGDLTNLVHEKFPQFITNVKGVSEETTTGVHNL YKMFKEGTLKVPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGKVAVVAGYGDV GKGCAQALRAFGSRVLITEIDPINALQAAMEGYEVTTIDEAIKEARIFVTASGCKGIIEA HHFEQMLDDSIVCNIGHFDCEIDVASLKAMAKKCDVVQPQVERYTLPNGNRVILLAEGRL VNLGCAHGHPSFVMSNSFTNQVLAQIELWTKPESYKIGVFFLPKKLDEEVAAAHLEHLGV KLTKLSEDQKDYLGLRSDGPFKPDHYRY--------TNTVEEPLDLIRLSLDERICVKMR NDRELRGRLHAYDQHLNMILGDVEETVTTIEIDEETFEEIYKSTKRTIPMLFVRGDGVIL VSPPMRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFRSLFDSARNSPF ASPFGALINENRIIKAA-EETSCEFGSAKYYALCGFGGILSCGITHTAVVPLDLVKCRIQ VNPDKYKGIFTGFKITLKEDGARGLAKGWAPTFIGYSMQGLGKFGFYEVFKNVYNGMLGE ENSFLYRTSVYLAASASAEFFADIMLCPMEACKVRIQTQPGWANTLREGFPKLKAEEGVF GFYKGIVPLWGRQIPYTMMKFACFERTVEALYKYVVPKPRAECTKPEQLVVTFVAGYIAG VFCAIVSHPADTIVSKLNQDKTARMVDVAKKLGLAGMWKGLFPRIIMIGTLTALQWFIYD SVKVAFKLPRPPPPEMPASLKAKLAHWKVERYLATALIPLIPASFIY------------- -------------------------------------------NDTQEEDASELQFPSEF ENAESLLVSEVKRKTQNESAEEEQELSEVFMKTLNYTQRISRFKNRETIAAVRNTLMQKK LHKFELAALANLCPETAEEAKALIPSLEGRFEDDELQSVLDDIQNKRSFQY--QPHLSRQ DLSNLVIEKLTPLTPEVISRQATINIGTIGHVAHGKSTVVKAISGVQTVRFKNELVRNIT IKLGYANAKIYKCSNKACPRPSCYRSCGSSKEDDFPCDRQGCGRFQLLRHVSFVDCPGHD ILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQ AKEQYEHILKFVEGTIAEGAPIIPISAQLKYNIEVVAEYIVKKIPVPIRDFTSEPRLIVI RSFDVNKPGFEVDDLKGGVAGGSILRGVLKVGQEIEVRPGIVSKDEDGKLSCKPIFSRIV SLYAEQNDLLYAVPGGLIGVGTKIDPTLCRADRMIGHVLGAVGTLPEIYTELEISYFRLR RLLGVKTEGDKKGAKVQKLAKGEILMVNIGSLSSGGRVIAVKSELAKIGLTNPVCTEIGE KIALSRRVEKHWRLIGWGEIRRGVTIKP-AELLLDTEIRLWVFLPIVLITFLVGIIRHYV TILLSSEKKVEMQQITDSQALIKSRMLRENGKYIPRQAYNMRKRFFNDEETGFFVKNPMT DPSMMTDMLKGNLTNVLPMLVIGGWINWAFSGFLTTKV---------------------- --------------------------------------------------------KAEW EALEIYDHQWELEGIEEEL-MFLWDWFSNMLSFLGLMKKSGKLLFLGLDNAGKTTLLHML KDDRMAQHVPTLHPTSEELSMGNMRFTTFDLGGHRQARRVWKTYFPAVDGIVFLVDAFDR ERFPEAKAELDSLMMDEQVMNAPVLILGNKIDKPGAASEDELRTLFGLHGQTTGKGNIPR TELRPVEMFMCSVLKRQGYGEGFRWMAQYINVLRRNRSGTKSSDWCNWPDESFEEMDSTL AVQQFIQQAIRKDFSNIDGILNPPDGQDEGVWKYEHLRQFCMELNGLAVKLQMECQPETC AQMTATEQWIFLCAAHKTPKECPAIDYTRHTLDGAACLLNSNKYFPSRVSIKESSVAKLG SVCRRVYRIFSHAYFHHRPMFDDFENETALCRRFTIFVMKYNLMSKDNLIVPILEEQ--- ---------------EIAKQSVTIKTMLEDEEDDDEVVPLPNVNTAILKKVIQWCTYHKD DPPPPEDDENKEKRTD---SWDADFLKVDQGTLFELILAANYLDIKGLLDV---TFANMI KGKSPEEIRKTFNIKNDFTPSEEEQVRKENEWCEEKXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----FIPPDGEFELMSYRLNTHVKPLIWVESVIERHQHSRVEYMIKAKSQFKRRSTANN VEIVIPVPQDADSPKFKTTVGSCKYSPETNNVIWTIKSFPGGKEYLMRAHFGLPSVEGED SEGKPPIHVKFEIPYFTVSGIQVRYLKIIEKTGYQALPWVRYITQNGDYQLRTQMGILEK IAEIEKEVARTQKNKATEYHLGLLKAKLARYRAQLLEPTSKSGAKGDGFDVMKSGDARVA LIGFPSVGKSTLLNTLTNTHSESASYEFTTLTCIPGVITYNGANIQLLDLPGIIEGAAQG KGRGRQVIAVARTADLVIIMLDATKSEVQRELLEKELEAVGIRLNKRRPNIYFKIKKGGG LSFNSTVPLTHVSEKLVQLILHEYKLFNCEVLFREDCTADEFIDVIVGNRVYMKCIYVYN KIDQISIEEVDKIARREDSVVVSCNMKLNLDYLLEVVWEYLALIRVYTKKPGEHPDLEGG LIMRRN-CTVEHVCHAVHRTLAADFKYALVWGSSTKYNPQRVGISHVLQHEDVIQIIKKM AKHHPDLIFCRKQPGVAIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGSYQGRCVIC GGPGVSDAYYCKECTIMEKDRDGCPKIVNLGSAKTDLFYERKKYGFKKR----------- -------------------------------------IRFNLKTRNVELKTCKETTDIGA LQKGADFVKAFTLGFEVDDSLALVRLDDLYLESFQVTDVKPLKGDHLARAIGRIAGKNGK TKFTIENVSKTRIVLADSKVHILGSYQ--------------------------------- --RIKVDKPVVELDGDEMTRIIWEKIKEKLILPYLDVECLYYDLGLPHRDATNDQVTIDS AHAILKHNVGIKCATITPDEQRVEEFKLKQMWLSPNGTIRNILGGTVFREPIICKKIPRL VPGWKDAIVIGRHAHGDQYKATDFVVPGAGKVELVYTPAGGEKVTHEVYNFKD-GGCVMG MYNTDESIRGFAESCFQMALMKKWPLYLSTKNTILKRYDGRFKDIFNEIYESKYKQKIEE AGIWYEHRLIDDMVAQALKSSGEFIWACKNYDGDVQSDVVAQGYGSLGLMTSVLVCPDGK TVESEAAHGTVTRHYREHQKGNPTSTNPVASIYAWTRGLEHRARLDGNKDLEKFCHDLER ACVDTVDSGLMTKDLAGCIYGLKNLKPDQYLYTMDFLEAI-----MGKLLSKIFGNKEMR ILMLGLDAAGKTTVLYKLKLGQSVTTIPTVGFNVETVTYKNVRFNVWDVGGQDKIRPLWR HYYTGTQGLIFVVDCADRDRIEEARQELHRIINDR------------------------- ----------------------------------------FGDLSTAAGVSVLNEYLADK SYIEGYEPSQADTVVFKSMKSPSVELFHALRWYNHILSFRDEADSFPGTKKSVSEYGPSV TDDDDDDDDFDMLASAAEERRKKAEAAYYEKKAPAVIAKSSIILDVKPWEDSTDLVEMER LVRTIQTDGLVWGASKLIPVAYGIKKLQIMCVVEDDKVGTDFLEENILGFEDHVQSVDIA AFNKI------------------------------------------------------- -------------------------GMAQALGTDTPFTSIAGSEIFSLEMSKTEALTQSF RKSIGVRIKEETEIIEGEVVEIQIDRPATGTGAKIGKLTLKTTEMETIYDLGTKMIESLT KEKVQAGDIITIDKATGKITKLGRSFTRARDYDAMGPQTRFVQCPEGELQKRKEVVHTVS LHEIDVINSRTQGFLALFSGDTGEIKSEVREQINSKVAEWREEGKAEIVPGVLFIDEVHM LDIECFSFLNRALESDMAPILIMATNRGITRIRGTNYQSPHGVPIDLLDRLLIITTSPYE EKDIKQILKIRCEEEDVEMSDDALTVLTRIGLETSLRYSIQLITTASLVSRKRKAAEVEV EDIKRVYSLFLDESRSSQFLKEYQQEFMFNEMAEFDLTTKIAQYLDRHLVFPLLEFLSVK ELYNEDEMLKGKLELLSNTNMVDFAMDVHKSLYPDQEVPKGLRDKRVDVVEELKQLQAAV DPITKIFEDQEVQIQQSRDGRQLFEFLAKNHDFQHDMLTTLYKFAKFQYECGNYSGAAEY LYFVRVLIPSHDKNFLNVLWGKLASEILMQNWDAALEDLNRLKDIIESSLQLLQQRTWFI HWSLFVFFNHPRGRDLIIDLFLYQPQYLNAIQTLCPHILRYLTTAVITNKTVLKDLVKVI QQESYTYRDPITEFLECLYVNFDFDGAQQKLRECETVLTNDFFLVACLDDFIENARLFIF ETFCRIHNCISISMLAEKLNMTPEDAERWIVNLIRNARLDAKIDSKLGHVVMGTQAVSPY QQVIEKTKGLSFRSQMLCMNIEKRLGVKS-----------------KKGQTAVVDYIGRL TDNTEFDSSVKRGKPFKFLVDLGHVIVGWDIAIKTMSVGEKSMVTCPSDVAYGDLGHPGV IPPKATLIFEMNLVKIEMPKYFCDYCDTYLTHDSPSVRKTHCNGRKHKENVRIYYTKWLE EQVQKLVDDTTAAYKSGKINTNPFNSQGAMIPPPPNLGSAAPMP-MPPHMPGPHGPMPPM RG---PMGPMMPMMGPP------------------------------------------- ------------------------------------------------------------ ---------------GPAAEGGQLKSGDQLLCVDETPVIGVHYDKAIEILRKAQGTVNLT I---------------------------LIGLAVSEPKVYFKETFAGDDWVVSEHK-SDL GQFKWTAGKFYGDADKDKGLQTSQDARFYGISRKFES-FSNEGKTLVVQFSVKHEQNIDC GGGYLKLYTSDANQKDLHGETPYNIMFGPDICGPATKKVHVIFSYKGKNLLIKKEIRCKD DVFSHLYTLIVKPDNTYIVKIDNEKVESGELEADWDFLPAKKIKDPEAKKPEDWDERETI DDENDKKPEDWDKPEHIPDPEAKKPDDWDDEMDGEWEPPQIDNPEYKGEWKPKQVPNPAY KGKWVHPEIDNPEYTADDKLYSFDSFGVLGLDLWQVKSGTIFDNMLITDDEKYAEEFGNE TWGKTKDAEKKMKDAQDEEERKKQEEEDKKAKEEEEKNEDKDDE------EPSLYTVKAI LILDNDGKRLIAKYYDDTYPTAKEQKNLFNKTHRANAEIIMLEGLTCVYRSNVDLFFYVI GSANENELILVSVLNAFYDAISQMLRKNVEKRALLDNLDAIFLAMDEICDGGIIMEADPS IIAQRVIIRNDDIPLGEQTVAQVIQSAKEQIKWSLLKMNIFRLVGDLSHLLAIVILLIKI WKTRSCAGISGKSQIMFAMVFLTRYLDLITSFVSVYNTSMKCVFIACSLATVFMIYSKFK ATYDSNHDTFRVEFLVVPVAGLALLVNHDFSPLEILWTFSIYLESVAILPQLFMVSKTGE AETITSHYLFALGSYRALYILNWVYRYYFEGFFDLIAIVAGCVQTILYCDFFYLYITKVL KGKKLSLPAMKIEEVKSTTKTQRIATHSHVKGLGLDETGMAIQSSAGLVGQEDAREAAGI IIELIRSKKMAGRAVLLAGPPGTGKTAIALAMAQELGSKVPFCPMVGSEVYSSEIKKTEV LMENFRRAIGLRIKETKEVYEGEVTELTPVETENPMGGYGKTVSHVVIGLKTAKGTKQLK LDPSIYESLQKEKVEVGDVIYIEANSGAVKRQGRSDTYATEFDLEAEEYVPLPKGDVHKK KEVIQDVTLHDLDIANARPQGGQDIMSMMGQLMKPKKTEITDKLRKEINKVVNKYIDQGV AELVPGVLFIDEVHMLDIECFTYLHRALESTISPIVIFATNRGCCTIRGTEDIVSPHGMP LDLLDRVMIIRTLPYSQDEMMQIIKIRANTEGITVNEESLKKLAEIGVKSTLRYAVQLLT PSNLLAKINGKETINEDEIEEINELFFDAKSSAKLLLEQQDKYMKEFEVDEDGDQGLLRL KEKVKKRKGRGFVIKTKNEEYEGMDMSGPGPQRSIEGWILFITGVHEEAQEDDIFDKFSE FGEIKNIHLNLDRRTGFLKGYTLVEYETFKEAQAALDALNGADILGQNISVDWAFVRGPT GKKMSYQIYRNTTLGHTLQESLDELIQCGQITPQLALKVLLQFDKAINTALASRVKSRVN FKGKLNTYRFCDNVWTFVLQNVEFRTVDKVKIVACDGKGTFLFTSESVGEGHPDKICDQV SDAVLDAHLKQDPNAMVACESCCKTGMILVCGEITSEAHVDYQRVIRDTIKHIGYDDSKK GFDYKSCNVLVAIEQQSPDIAQGVHVNRNEEDIGAGDQGLMFGYATDETEECMPLTVVLS HQLNAKIAELRRTGELWWAGPDTKTQVTIDYKFHMGACIPQRVHTVVISAQHAEECTMDV LRSDLMEKVCKAVIPAKYIDDKTIFHLNPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAH GGGAFSGKDFSKVDRSAAYAARWVAKSLVKAGLCKRVLVQLSYAIGIAQPISISIFSYGT STKSEDELLRIVKKNFDLRPGGIVKALNLKRPIYQRTAAYGHFGRKEFSWEQPKEL--MA GSALKRLMAEYKQLTLNPPEGIVAGPLTEENFFEWEAYITGPEGTCFDGGVFAALMSFPP DYPLSPPKMKFTCDLFHPNIYPDGRVCISILHAPGDDPMGYETSAERWSPVQSVEKILLS VISMLAEPNDESAANVDAAKTWRDNREKFEEIAERTVRKSLGLMRLEKCYYCSSTVYPGH GVEFVRNDCKVFRFCRGKCHKAFKKKRNPRKSKWTKAFRKAAGKDLAVDPSLEFEKRRHV PIKYDRELWKKTIDAMKRVEEIKLKRQNQFIKNRLKKGKELRKEADIKAVKQSIHLIKSP AAT---YKIVLVRHGESEWNKLNLFCGWHDAPLSQTGIAEAHDAGKLLKEKGYTFDVAYT SVLKRAVKTLNIIQEELDLDWIPVHRHYRLNERMYGGLTGLNKAETAKLHGEDKVKIWRR SYAIPPPDVDLDSSEYPGNDRRYKMVDKSLIPRAECLKDTVERVLPYWFDAIVPSILSGQ RVIVSAHGNSLRGLVKYLDKIPDDEIVGLNIPTGLPLVYELDEDLKPVKHYYLASEEEVA ARVAKVVAQGKSKMELSDKYYNKPEYIETASGNKVSRQSVLCGSQNIVLNGKTIIMADCI IRGDLANVRIGRHCVISNKAVIRPAFKKFSKGVAFFPLHIGDHVFIDQDTIVNAAQVGSY VHIGKNCVIGRRCVLKDCCAIADNTVLPPETVVPPFTLFSGSPGMSFLFGSRNNKTFKPK KNIPEGTHQYDLMKHAAATLGSGNLRLAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTIT EFCMEEKCPVMSAGPKYEYHWADGQTVKKPIKCSAPKYIDYLMTWVQNQLDDETIFPSKI GVPFPKNFLSIAKTILKRLFRVYAHIYHQHFSEVVSLSEEPHLNTSFKHFIFFVQEFNLI EKKELAPLSELIERLTSKEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXX--------------------------------- --------------------------------------LVERGQLFLQTVGTSRSALPFI TDGKTIRVVLQIFKDRFRVFVTERTGQSMYDELTALGIPTTLILDASIGYVMEKVDFVLM GAEGVAESGGIINKGTYSVAMCAKELNKPFYVLAESFKFTRLYPLN-QDLPNQFKYHASQ EHPWVDYTPPAYITLLFTDLGILMPS-----------XXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRSPEPVEGRKHIDVQT ELYLEELSDRVEEADVDCQTDAFLDRPPSPLFIPAKSGVDVATQILEGDLFNFDVEVRPI LEVLVGKTVEQSLLEVMEEEELANLRSQQRAFEELRNAELVEQQRLEEQERRHREEKERR KKQQRDILEREKETADKIAARAFAQSYLADLVPSVFGTLADNGYFYDPVERDVEQGFIPW LMDQVEEKLNKVTHGRMVLDGIIRDVVKNRFHSYAQMKARGQLKEYKVIGRMLPTDKQPV PPLYQMRIFATDRVTAKSRFWYFAQQLHKMKKTLGEIVCCQLVSDKRPLKIKNLGIWLRY DSRSGSHNMYREYRDLTISGAVTQCYRDMGARHRARSHSIQIMRVEEIPANKCRRPHITQ FHNSKIKFPLPHRTSRPLHAPRFTTARPHTTY-AIKEMEYFWHKNESRPMSPLSIYKVEV TSLLSITHRLTGVGLSVGLIGLGW-LSLYNTNFRLFADGALEL-VGPWGVFATKAVLVWG MVYHLLNGIRHLVWDRAVGLKISAISKSGLAMLAAL--------LSAYRDQHFRGDRKQQ EVCLLTSCTLYVGNLSFYTTEEQIYELFSKCGDLKRIVMGLDKFKKTPCGFCFVEYYLRE DAEMSMRYINGTRLDDRIIRTDWDAGFKEGRQYGRGKTGGQVRDEYRTDFDSGRGGYGKI IVSKIKPNYTLKFTLAGHTKSVSSVKFSPNGEWLASSAADKLIKIWGAYDGKFEKTISGH KMGISDVAWSTDSKYLVSASDDKTLKIWELAAGKCLKTLKGHSNYVFCCNFNPQSNLIVS GSFDESVRTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG KWIVSGSEDNMVYIWNLQTKEIVQTLQGHTDVVLCCACHPTENLIASAALENDKTIKLWK SDIMKVFQDHFTGEDVFSDAYKDLYYTVDGKSESLIGGNRSWEVDLIGS----------- ------------------------------------------------------------ -----------------------------DICKYNMNFYKMQMNDEPTVATAARIFQNMC YGYRDQISAGIIVAGWDKQKGGQVYSVPLGGALIRQPVAVGGSGSTYIWGYVDAHFKENM TKKECEDFVTNSLALAMIRDGSSGGVIRTATITEKGVERRLILNDDLPKF---------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YADIASKILTFAVYDFDRFSKHDQIGLVKVPLNSVD LGRVIEEWRDLTSPEAEGEKENKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSD PYVKLALYQGTKRLKKKKTTIKKRTLNPYYNESFTFEVPFEQIQKVTLIITVVDYDRIGT SEPIGRIVLGCNSSGTELRHWSDMLANPRRPIAQWHTLQEMPEKSMVLADLGRKITSALR SLSNATIINEEVLNAMLKEICAALLEADVNIKLVKKLRENVRSVIDFDEMAAGLNKRRMI QSAVFKELVKLIDPGVKAWTPTKGKNNVIMFVGLQGSGKTTTCTKLAYHYMKKGWKTCLI CADTFRAGAFDQLKQNATKARIPFYGVDTSGRHKQEDSLFEEMLQVSNATPDNVVFVMDA SIGQACESQAKAFKDKVDVASVIITKLDGHAKGGGALSAVTHSPVIFIGTGEHIDDFESF KVQPFVSKLLGMGDIEGLIDKVNELKLDDEELMNKIKH---------------GQFTLRD MYEQFQNIMMSIMSYNGAAIMAMIGKDCVAIATDTRFGVQAQTVSTDFQKVFEMGPRLYL GLPGLATDVQTVHQRLRFRKNIYELKENRPIKPHVFMSMVSNLLYERRFGPYFVEPVIAG LDHVTGKPFIASMDLIGCPMITEDFVVSGTCNEQMYGMCESLWEPNLEPDDLFETISQAL LNAFDRDCVSGWGAVVHVIEKDKVTTRSLKTRADMTSKDYYFDSYAHFGIHEEMLKDEVR TLTYRNSMYHNRHLFRGKTVLDVGCGTGILCMFAAKAGAKKVIGIECSGIVEHAQKIIDA NKFTDVIKLVKGKVEEVTLPEGIEKVDIIISEWMGYCLFYESMLNTVLFARDKWLGPNGM IFPDRATLYVTAIEDRQYKDEKINWWDTVYGFDMSCIRSVAITEPLVDVVDPKQVVSNSC LLKEVDMYTVKIEDLSFTAPFHLTIKRNDYVQALVTFFNIEFTKCHKRTGFSTAPEAPYT HWKQTDDYVTVKQNEEVTGVFEMKPNSRNNRDLDFKIDIAIEGELSSLSETLTYKM---- ------------------------------------------------------------ -----------------------------DVRQKLLENKVQAPAKAGAIAPLDVTIPKQN TGLGPEKTSFFQALSIPTKIARGTVEILNDVRLISEGDKVGASEATLLNMLNISPFSYGL TIYQVYDSGTVFSPEVLDITDEDIRKKFLQGVTNVASLSLQIGYPTIASVPHSIVNGFKN LLSLAAVTDITFKEAETMKE------LIAVIGDEDTCTGFLLGGIGELDKHRHPNFLVVD KNTSVGEIEESFKGFVARDDVAIVLITQNIAEMIRHILDNYMEATPAVLEIPSKDYPYDA SKDSILRRAKGIFSAEDFRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXMTYITSWEEFAKAAERLYLADPTKARFSMKYRHCDGKLTVKLTDNHVCLMYR TEHAQDVKKLERFTSHLMRHMSSKELYEEVKLYKTGKEREKYDNMADLFAVINTLQCLEK AYIKDAVTPKEYTAACSKLLVQYKAAFRQVQNDEFPTVEAFTKKMKLDCPAALERIKEDR PITIKDDKGNTSKCIADIVSLFITVMDKLRLEIKAMDQIYPDVKELMESMSALSILPNDF EGKDKVEQWLSTLSQMQVSDELDDNQVRQMLFDLESAYNDFNRVLH-MLSSLLKQHQQKQ QARKDSQEKKKKEVTTVTKLTHALVDHLNAGVAQAYVNQKKLDTETKILQANAAQFAKQT TLWLRLVEDFNTALKEIGDVENWSRSMETDMRTISSALEYAYKXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXLEWLFGRKKTPEEMLRQNQRLLTRAMRDLDRERSKMEQQEKKVINDIKKMAKEGQMDA VKIMAKDLVRTRRYVKKFILMKANIQAVSLKIQTLRSNNAMAQAMKGVTKAMQTMNKQLK LPQIQKIMMEFEKQSEIMDMKEEMMNDAIDDAMGDEDDEDESDAIVSQVLDELGLQMADQ LSDIPTTAAA------GVSDADADLEARLENLRR-SQYCDFCLGDSAENKKTNQPEELVS CSDCGRSGHPSCLQFTANMILSVKKYPWQCIECKSCGLCGTSDNDDQLLFCDDCDRGYHM YCLDPPLSEPPEGSWSCHLCIEEFHG--DRPINLYPLTNYTFGTKEPLYERDNSVQARFA RMREEFNKTGMRRSVEGVLIVHEHGLPHILLLQLGTTFFKLPGGELNSGEDEVAGLKRLL TETLGRQDGVPVDWVIEDVAARWWRPNFEPPQYPYIPAHITKPKEHKKLFLVQLPEKALF AVPRNYKLVAAPLFELYDNSAGYGPIISSLPQTLSRFNFIYNLTPSGATPAGPKAMAMAT PTPGHLMSMTPEQMQAYTWQREIDERNRPLSDDELEAMFPPGYKVLQPPAGYAPIRTPAR RLIATPTPIAGTPVGFRIQTQVVDMQPKGNLPMMKPDDIQYFDRKIMKLLLKIKNGTPPM RKAALRQITDKAREFGAGPLFNQILPLLMSPTLEDQERHLLVKVIDRILYKLDDLVRPYV HKILVVIEPLLIDEDYYARVEGREIISNLAKAAGLATMISTMRPDIDNMDEYVRNTTARA FAVVASALGIPSLLPFLKAVCKSKKSWQARHTGIKIVQQIAILMGCAILPHLKNLVEIIE HGLVDEQQKVRTITALALAALAEAATPYGIESFDSVLKPLWRGIKQHRGKGLAAFLKAIG YLIPLMDAEYANYYTREVMLILVREFQSPDEEMKKIVLKVVKQCCATDGVEPQYIKDEIL PPFFKHFWNQRMALDRRNYRQLVDTTVEIANKVGAAEIVGRVVDDLKDEAEQYRKMVMET IEKIMANLGGADIDSRLEEQLIDGILYAFQEQTTEDVVMLNGFGTVVNALGKRVKPYLPQ ICGTILWRLNNKSAKVRQQAADLISRIAIVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLG SILGALKAIVNVIGMTKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGSEFVS AREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVC TTVAIAIVAETCSPFTVLPGLMNEYRVPELNVQNGVLKSLSFMFEYIGEMGKDYIYAVTP LLEDALMDRDLVHRQTSMAAIQHIALGVYGFGCEDALIHVLNHVWPNVFETSPHVVQAFM GAIEGIRVGLGPSKILQYTLQGLFHPARKVRDVYWKVYNTVYIGAQDAMIPSFPRIPNDV KNQYLRYELDYVLDDFMCDDEEYNLEYSEDSNSEPDVDLENQYYNSKALKEDDPRLALES FQKVLELEGKDKGEWGFKALKQMIKINFKLGNFDEMMNRYKQLLTYIKSAVTRNYSEKSI NSILDYISTSKQMKLLQNFYETTLEALKEAKNDRLWFKTNTKLGKLYFDREEYTRLQKIL KQLHQSCQTADGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPL IMGVIRECGGKMHLREGEYEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGIN PFDSQEAKPYKNDPEILAMTNLVSSYQNNDINEFEKILKMNRKNIMEDPFIREHIEDLLR NIRTQVLIKLIMPYTRIHIPFISKELNIDVTEVENLLVSCILDSTIQGRIDQVNQVLELN Q-VARYSAIDKWTTQLQSLHQSVVNKMAVLLMGKSGSGKTSMRSIIFANYIARDTRRLGA TIDVEHCHVRFLGNLVLNLWDCGGQEAFMENYFASQRDNIFRNVEVLIYVFDVESRELEK DMHYYQSCLEAILQNSPDAKVFCLVHKMDLVQEDQRDIIFKEREEDLRRLSKPLATSIWD ETLYKAWSSIVYLLIPNVQQLETNLTNFANILDADEVLLFERATFLVISHCQRKPHKDVH RFEKISNIIKQFKLSCSKLAASFQSMEVRNSIFAAFIDIFTSNTYVMVIMSDPSIPSAAT LINIKNARKHFEKLERIDQ----------------------------------------- ------------------------------------------------------------ --------------------TFVIVRSGDRTRNIPGSYDNEGIAIFCMLLTYLLWIKSVK TGSAFWSVLCALAYFYMVSSWGGYVFLINLIPLHVLLLMLTGRFSHRIYVAFSTVYAIGT ILSMQISFVGFQPVLSSEHMAAFGVFGLCQIHAFVDYLRSRLSAEQFETLFRSVALVLGI SLLTVTGKIAPWTGRFYTLLDPSYAKNHIPIIASVSEHQPTSWSSFYFDFQMLVFMFPVG MYFCFKKLTDANIFIIMYGMTSIYFAGVMVRLMLVLAPVMCIVSGIGISSILTTYMKNLD VKKSEDSSYPIKNEVATGVILLLTLFLITYTTHCTWVTSE-------------------- --------------------------------SMANRTILVDNNTWNNTHISRVGQAMAS PEDKAYEIMRELDVDYVLVIFGGMTGYSSDDINKFLWMVRIGGSTDRGSHIKEHDYYTPQ GEFRIDKEGSPTLLNCLMYKLSYYRFGSVYTENGKPTGYDRVRNKEIGNKDFQLDVLEEA YTTQHWLVRIYKVKDLQNRG-KLNIRPLLQLILRKFFGDFTGFVDMCVEHVKSPVANARA KIEHIYTGSLDNELAESMLACDPDGPLMVHTTKLYPTNDATTFHVMGRVMSGTLHANQDI KVLGENYSLQDEEDSRFGQVGRLWIFESRYRVEVNRVPAGNWVLIEGVDQPIVKTATITE ATGNEDALIFRPLRFNTSSVVKIAVEPVNPSELPKMLDGLRKVNKSYPLVTTKVEESGEH VILGTGELYLDCIMHDLRKMYSEIDIKVADPVVSFCETVVETSSLKCFAETPNKKNKVTM IAEPLEKGLAEDIENEVVQISWPRKRLGEFFQTKYDWDLLAARSIWAFGPDTTGPNILVD DTLPSEVDKNLLSSVKDSIVQGFQWGTREGPLCDEPIRNVKFKILDAVIAQEPIHRGGGQ IIPTARRVAYSAFLMATPRLMEPYNFVEVMAPADCVSAVYTVLARRRGHVTQDAPVPGSP LYTIKAFIPAIDSFGFETDLRTHTQ----------------------------------- ----------------------------------------------EVFSLFDNKGDGKI YGNQLGDVLRAIGENPTEADVRKHSETDKRISFEEFIPILATVCKNRDGSKITDFIEGFR VFDKEQNGLISSAELRHLLTHLGERLKDEEVEQLLSGMEDPQGNVNYEEFVNTVYNG--- LYFNIDNGYLEGLVRGFKAGILRQNDYLNLVQCETLEDLKLHLQSTDYGNFLANEASPLA VSVIDDKLKEKLVLEFQHIRNQAVEPLATFLDFITYSYMIDNIILLITGTLHQRSIAELI TKCHPLGSFETMEAIHIAATPAELYNAVLVDTPLAPYFIDCISEQDLDEMNIEIIRNTLY KAYLENFYQFCKDLGGPTAEVMCEILAFEADRRAFIITINSFGTELTKDDRAKLFPECGK LHPDGLAALARADDYDQVRAVAEYYAEYRALFEGSGNNPGEKTLEDKFFEHEVKLNMNAF LQQFHYGIFYAYMKLKEQECRNIIWIAECVAQRHRAKIDSYIPIFSPRKAVRKISKIPFK VLDAPELQDDFYLNLVDWSSTNVLSVGLGTCVYLWSACTSQVTRLCDLSVDGDSVTSVSW SERGNLVAVGTHKGDVQIWDVAASKRISLLEGHSARVGALAWNADILSSGSRDRLILQRD IRSPSIVPERKLTGHRQEVCGLKWSPDHQHLASGGNDNKLFVWNMTSLSPVQTYTEHLAA VKAIAWSPHQHGLLASGGGTADRCIRFWNTLT---------------------------- ------------------------------------------------------------ ----------------VATLIGLYYILSGQGYRFDIGWFLEETSPYVWANLGVGLAISLS VVGAAMGIYMTGSSILGAGVKAPRIKTKNLVSIIFCEAVAIYGIIMAIVISNIDNIFAGF AMLGAGLTVGLSNLACGICVGIVGSGAALADAQNSSLFVKILIVEIFGSAIGLFGVIVGI LQISKAKMGGKMAATRRLNKELEEIVDESNVLNWQGLIVPDHPPYNKGSFKIEIVFPAEY PFKPPKITFKTKIYHPNIDEKGQVCLPIISPENWKPATKTDQVIQALVALVNDPEPEHPL RGDIADEYTKDRKKFMKNAEEYTKKYGERRP--XXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------- -------------------------PHFIAVMRSGEIVVSDIVQNEVYFLTNFEKRRVYV QK-SQAMKLEFPCGITIDHTGHILIADWSNSRIHELSTEGEFIRVLLIRHPRAITIDNEG NLVVCESG-----------AAGPIAERNQDATVYVGGLDDKVSEAILWELFLQSGPVVNV HMPKDRITQSHQGYGFVEFMSEEDADYAIKIMNMIKLYGKPVRVNKASAHQKNLDVGANI FIGNLDPEVDEKLLYDTFSAFGVILQTPKIMRDPETGNSKGFAFINFASFEASDASIEAM NGQYLCNRPISISYAFKKDSKGERHGSAAERLLAQQNPLSQADRPHQLFADAPPTAQSSP MAPPPPPPSG---------MPGGGIPPPPMPPMGGMPPPGMHPPPPPPPSGPPPPGMRFP PPGPPPRGMRPPPGMRPPP-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXMRYVAAYLLAVLGGNKSPSKKDIEKILESVGIDCEAENVNK VISELSGKDIEELMEAGRAKLASVPSGGSAVA-------------------MSIVKVHAR QIYDSRGNPTVEVDLTTDKGTFRAAVPSGASTGIHEALELRDKDKAVHHGKGVLKAVENV NSIIGPALVVKVTDQSAADKMMLELDGTENKSKLGANAVLGVSMAICKAGAAHKGIPLYR HIADLAGHKDVILPVPAFNVINGGSHAGNKLAMQEFMILPTGAKNFTEAMRMGSEIYHHL KAVIKSKYGQDACNVGDEGGFAPNIQDNKEGLELLKTAIAKAGYTDKIKIGMDVAASEFY KKYDLDFKNPNSDASKHLSAAQLADLYKDFVANYPVVSIEDAFDQDDWSAWSDLMKVQLV GDDLTVTNPKRIKTAIDKKACNCLLLKVNQIGSVSESIEACKLSNANGWGVMVSHRSGET EDSFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELGGSAKYAGEKFQHPGKPPK AGAYEPKDCGSTEFKRCYKRGDFPIALEHDTKGNKIAWKVEIEKLDYHHYLPLFFDGLRE TEHPCEFFARQGVHDMLEHGGQKILPVIPQLIIPIKRSLNTRKPGVVCTTLKILQHLVVS GNLVGEALVPYYRQILPILNTFKNKNINSGDGIDYSQQKRENLGDLIQETLEEFERQGGE DAFINIKYMVPTYESC-MNAPPSFESFLLFEGEKKITIQKDTKVPNAAIFTIKKEDHTLG NALRGQLLKDPQVLFAGYKVPHPLEHQFVLRIQTSPDYSPQEAFQNAITDLISEVSLLEE QFRDAVKEKQEGDDDHRRKWDPEEFERIAQKKIEEEFNSYPEPVKRELLKPRDYKVDLES KLNRSTVITKTTPASEQGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMKVERSTLD QVKRRFEMNKKKKEEKKKDYDFTERMKELREEEEKQKSYRKEKRKERKRKADDSVDDPDM ASLMGFSGFGTSKKMGCTMSAEERQALQISRDIEKRIQDDGKQA---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YHS SL-SSPLSAAKMAILPLKTKFRGPAFDIIDEALSFFKANVFFKNYEIKSEADRTLIYVTL YITECLKKLQKCQTKNDGSKEMLTMAIAAFDIPGEQRFPLNALYGKAQDRAEGDLLRSYL IQLRQETGARVVEKVYDPVTNKPSKWWMCFVKRKFMDKSLSAPGQAGPYNYSYIFKYIII GDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVT RSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIFLIGNKSDLEAQRDVTYE EAKQFAEENGLMFLECSAKTGENVEDAFLDTAKKIYQNIQDGSLDLNAAESGVQHRPSGP GNQLGPTPSADKDGCSC------------------------------------------- -----------------------------------------------------QLVGVNS IIGRSVVVHADVDDLGKGGHELSKTTGNAGGRLACGVIGIAK----SIDEIRGQMERKAN VRNMSVIAHVDHGKSTLTDSLVSKAGIIASSKAGDARFTDTRKDEQERCITIKSTAITMF YEVDDIVLGNQFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQA IAERIKPVLFMNKMDLAISSRQLASEELYEAFRNSIENVNVIISMYCEEGGPMGDIMVNP MNGTVGFGSGLQGWAFTLRNFAQIYAGRFKIPVEKLMKRLWGDNWYYRVRGFCQFILDPI YRVIDTIKKRETVYTFVEKIGVKLIPDDKELDDKKLAKRIMQKWLPAGETLLEMICMHLP SPITAQKYRMELLYEGPHDDEAAIAIKECNVDGPLMMYVSKMVPTSDKGRFYAFGRVFAG TVASGQKVRIMGPNYTVMKSIQRTVLMMGRSVEQIPDVPCGNICGLVGVDQYLVKTGTIS TFEHAHNLKVMKFSVSPVVRVAVAPKDPSHLLKLIEGLKRLAKSDPMVQVTLDDTSQNIV AGAGELHLEICLKDLEEDHACVPISKSDPVVSYRETVTEESP-VCLSKSPNKHNRLYLKC KPM-----------------------------------EARKIWCFGPDSNGPNVVVDAT KGVQFLNEIKDSVVAGFQWASKEGVLCEENLRGVRFDIKDVTLHADAIHRGGGQIIPTTR RVCYACQLSGVPRLMEPIYLVEIQCPQAAAGGIYPVINARRGIALGNLEVPGTTMVIAKC YLPVNESFGFTSKLRQETGGQAFPQCVFDHWDVLVVKTTRHRKGLTEGIPPLDKFQDKLX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXNEFKLKQPPSDGISAAKFSPSSTQFLLASSWDGSVRLYDVLNNSMRLKYTHNAPVLD CCFYDAVHSLSG---------------ETKIGYHSMAIKCVEYCPDVNVVVTGSWDSTIK LWDPRAPTCTGSYPQPDKVYTIGVCGDRLIVGTARRKIMVWDLRNMS-VQQKRESSLKYQ TRSIRCFPNKQGYVLSSIEGRVAVEYLDPSPEVQKKKYAFKCHRIKEDGIEKIYPVNAIA FHSSFNTFATGGSDGFVNIWDGFNKKRLCQFHRYPTSIASLSFSNDGSLLAIASSYMFEQ DQPEDNIFIRNVTDQETKPKMDFQHRAGGKTGTGGVASSSESNRDRRERLRQLALETIDI NKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQANLARRAAKEAKDAPAQPAPE KARVDIKKFVKIGRPGYKVTKQRDPETGQQSLLYQIDYPEIVESITPRHRFMAAYEQKVE PPDRKWQYLLFAAEPYETIAFKVPSREVDKDPKKLWTHWNKETKQFFLQFAFKADQK-MG PPPPMGRPP--------------------------------------------------- --------DLTVLVAHNDDPTDQMFVFFPEDPKVGIKTVKSYCQTMQKENIHRALIVVQT GMTPSAKQSLVDMAPKYILEQFLESELLVNITEHQLVPEHVLMTPEEKKELLERYKLKES QLPRIQVGDPVARYFGLKRGQVVKIIRPSETAGRYITYRLVVADKESVGTVIGIDLGTTY SCVGVFKNGRVEIIANDLGNRITPSYVAFTSEGERLIGDAAKNQLTSNPENTVFDVKRLI GREWVDKNVQHDLKLLPFKVVNKNQKPHVEVKVDTKDRVFAPEEISAMVLGKMKETAEAY LGKKVTHAVVTVPAYFNDAQRQATKDAGTISGLNVMRIINEPTAAAIAYGLDKKDGEKNI LVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKSKDVRS NNRAVQKLRREVEKAKRALSAGHNTKIEIESFFDGDDFSETLSRAKFEELNMDLFRSTLK PVQKVLEDSDLKKHEINEIVLVGGSTRIPKIQSLVKEFFDGREPNRGINPDEAVAYGAAV QAGVLSGEEDTGDLVLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQIFSTAADNQPT VTIQVFEGERPMTKDNHLLGKFDLTGIPPAPRGVPQIEVTFEIDVNGILKVSAEDKGTGN KEKIVINNDQNRLSPEDIQKMINDAEKFSDEDKKVKDKVDAKNELEGYAYSLKTQINDKE KLGAKLSADDKDTMEKAIDAKIQWLEKNGDADTEEFKTQKKELEDTVQPIITKLYQGTPP GGEEAGKDEL--------------------------------------------ADARSI HVANVDYGATAEELEQHFHGCGSINRVTILCDKYTGHPKGFAYIEFADKDSV-------- ------------------------------------------------------------ ----VVSGTLAEIMQEGKYNTLLDAVKQEKSKKQQLQSTILKEEEGRKRVRMLQKKILDV KKEKEVEIQNRNEMIAHLKDQLQEMKAKTNMEGKYIKKCAEVSVAQTQKRCFLSEKDLKD EMERLRNQIDEETRVNAEIEAYLREHQTELEQKVDHWMEKYDKDVEAKQHELDVLNASKA KDLERLQELTKIYQEYEQVVVDDRIEKEKARRKAEQEALELNSCIRVQSWWRGMMVRKAI GPHGKKKKGKPQVGINGFGRIGRLVMRCAIESVDVVAVNDPFIDLEYMVYMFKYDSTHGR FKGEVGLCINGKNIKVHNERNPADIPWKADGVTYVVESTGIFTTTEKAGVH---NSEKVI ISAPSADAPMFVMGVNHEQYDKSVKVVSNASCTTNCLAPLAKVINDNFGIEEGLMTTVHA YTATQKVVDAPSSKKWRDGRTAAQNVIPASTGAAKAVGKVIPSLNGKLTGMAFRVPVPDV SVVDLTCRLKKGATMDEINATVKKELKGILAYTDQEVVSSDFIGDSNSSIYDSKACIALN NNFVKLVSWYDNEYGYSNRVVDLIVY-----QEELATAILRKKEKPNRLIVEESINDDNS VVSLSQAKMEELQLFRGDTVQLKGKRRRDTICIVLSDDTVHDEKIRLNRCIRSNLRVRLG DVVSIVACPDVKYGKRIHVLPLDDTVEGLTGNLFDVYLKPYFLEAYRPMRKGDIFIVRGG MRAVEFKVIETDPSPFCIVAPDTVIHCEGEPVKREEEEEALNEVGYDDIGGCRKQLAQIK EMVELPLRHPQLFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGSFFFLINGPEIMSK LAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQ RSHVIVMAATNRPNSIDGALRRFGRFDREVDIGIPDATGRLEILRIHTKNMKLSDDVELE QIAAETHGHVGSDLAALCSEAALQQIRGKMDLIDLEDETIDAEVLDSLAVTQEDFRWALS KSNPSALRETAVEVPSVTWQDIGGLESVKKELQELVQYPVEHPDKFLKFGMTPSKGVLFY GPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFD ELDSIAKSRGGNLGDGGGAADRVINQLLTEMDGMSSKKNVFIIGATNRPDIIDPAILRPG RLDQLIYIPLPDEKSRVSILKANLRKSPVAKDVDTDFLAKSTAGFSGADLTEICQRACKL AIREAIEEDIKRESEKDADD---DPVPEISREHFEEAMKFARRSVTDNDIRKYEMFAQTL QQSRGFGG----MFGAPKVFGGGTNSNPMKDIEVASPPDDSVSCLEFSPGTLPSTFLVAG SWDNNVRCWEVQGNGQTIPKAQQTHTGPVLDVAWSDDGSKVFTASCDKTAKMWDLNTNQA TQIAQHDAPVKTIHFIKAPNYSCVMTGSWDKTLKFWDMRSPNPMHTIALPERCYCTDVMY PMAVVGTANRGLIIYQLENQPQEFKKMESPLKYQHRCVKIFTDKKTSQPTGFALGSIEGR VAIHYVNPTNPKDNFTFKCHRNGVQDIYAVNSIAFHPQHGTLATVGSDGRFSFWDKDART KLKTSELLDQPISASAFNAQGNIFAYASSYDWSRGHEGYDPTKMKPHIFLRSCFDELKPS SKKMSSPSPGKRRIDTDVVKLIESKHEVTLLKGLNEFVVKFHGPPGTPYDGGVWKIRVDL PDRYPFKSPSIGFVNKIYHPNIDEASGTVCLDVINQAWTALYDLLNIFETFLPQLLSYPN PIDPLNGDAAAMFLHKPEDYKKKVAEYVKKYATEDAYRGSESSMSDFSEDEAQDMEL--- -----------------------------TFDPEQAATIGVDFKVKTLTVDGNRAKLAIW DTAGQERFRT----YYRGAQGVILVYDVTSKQTFQKLEAWLSELETFSTKHDIIKMLVGN KIDSDKREVSRDEGLKFARKHQCLFIEASAKTKEGVQCAFEELVEKIIQTPGLWETD--- ---VIWSIINGSFCSFKIKTKAQKFCRNEYNLTGLCDRSSCPLANSQYATIREEKGICYL YMKVIERSAFPNRLWEKVKLSRNYEKALEQISENLVYWPRWIIHKCKQRFTKITQYLIRM RKLTLRRQRKLVPLQTKIERRERRREQKALVAAQLETAIEKELLERLKQGTY-------- ---------------------------------------LNQVRCAVAPRMKKFQIYRYN PEKPGDKPHVQTFEIDLNSCGPMVLDALIKIKTDLDPTLTFRRSCREGICGSCSMNIAGS NTLACLAEIDQNLSKTTKIYPLPHMYVIKDLVPDMTNFYAQYRSIEPYLKKKDVSEEDIG KEPYSQTPEQRAKLDGLYECILCACCSTSCPSYWWSGDRYLGPAVLMQAYRWMVDSRDDY TVERMREMEDKFSLYRCHTIMNCTKTCPKGLNPGLAIGEIKKMLATTSH------DIRPN HTIYINNLNEKIKKEELKKSLYAIFSQFGQILDIVALKTLKMRGQAFVIFKEINSATNAL RSMQGFPFYDKPMRIGYSKKDSDVIAKLKGTFQERPKRKKPEKKKKKTKGASSTAIPEQP PNQILFLTNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENDMQAAAAKDALQ GFKITPTNAMKIAFAKKMDDKGNKVIVCDNGTGFVKCGYAGSNFPAHIFPCMVGRPLIRS TAKIGNIEVKDLMVGDEASQLRSMLEVNYPMENGIVRNWDDMLHIWNYTFGSSKLDIDPK HTKILLTEPPLNPMKNREKMVEAMFEEYQFDGVYIAIQAVLTLYAQGLLTGVVVDSGDGV THICPVYEGFALPHLTRRLDIAGRDITKYLIKLLLLRGYAFNHTADFETVRMMKEKLCYV GYDIEQEQKLALETTVLVEHYTLPDGRVITIGGERFEAPEALFQPHLINVEGVGVAELLF NTIQAADIDTRPEFYKHIVLSGGSTMYPGLPSRLEREIKQLYLERVLKGQVDKLSKFKIR IEDPPRRKHMVFLGGAVLADIMKNKDDFWMSRQEYEEKGLKVLKKLGVSMCSTQNKSISC KAAVCWKIGE-LKIETIQVAPPKTGEVRVKVVATGVCHSDAFSNSPRDSAPLLPRILGHE GAGIVESVGEGVTNVKPGDHVLMTLLPQCDDCRICKSKGNYVCERVNGGFGSGFMPDGTS RFSCNGKSLYNFLGLSTFTEYTVVSKLKVFKLADNVPFDKVCLLACGVATGFGSATNAAG VQVGDNCAVWGLGAVGLAAVMGCRYAGAKRIIGIDIVSEKAEMGKVFGLTDFINPLELDR PIEEVIKEMTDGGLDYAFECCGNIKTLEASFKCIHPSFGTVIQVGLTPDGSTLNIDPSLF RAGRRWRGACYGGLKSMDDIPKLVDLYMTSGVLLDEFVTHTMPLERIQEAFDLMEQGKSM DTYDVIANQPVVIDNGSGVIKAGFAGDQIPKYHFPNFIGRPKHVRIMAGALEGDVFLGPK AEEHRGLLTIRYPMEHGIVTDWNEMERIWQYIYSKDQLQTFSEEHPVLLTEAPLNPRRNR EKAAEIFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFALPHSIM RVDIAGRDVTRYLQLLLRKEGHNFNTSAELEIVRTIKERACYLAINPQKEETIETEKTQY SLPDGSVLEVGQARYRAPELLFRPDLIGDESVGIHEVLIYAIQKSDMDLRRTLFSNIVLA GGSTLFKGFGDRLLGEAKKLAPKDIKLRISAPQERLYSTWIGGSILAALDTFKKMWVSKR EYEDEGVRSIHRKTFAPKNIEKVVVHPLVLLSVVDHFNRMGKVGNQKRVVGVLLGANRHG VLDVSNSFAVPFDEDDKDRTVWYLDHDYLENMYTMFKKVNAREKIVGWYHTGPKLHQNDI AINELIRRYCPNSVLVIIDAKPKDLGLPTEAYYAVEEVHDDGTPTSKTFEHIPSEIGAEE AEEVGVEHLLRDIKDTTIGTLSQRVTNQLLGLKGIHVQLEDIYRYLEQVSDANLPINHQI VYQLQDIFNLLPDANLQEFVKAMYVKTNDQMLVVYIASLMRAIVVLHNLINNKLHNRDSE KNEGKKDTMGVLLTRLWSFFTNEEHKVIIVGLDNAGKTTILYQFLMNEVVHTSPTIGSNV EEVVWKNIHFLMWDIGGQDSLRSAWNTYYSNAQFVIMVIDSTDRERLPITKEELTNMLAN EELKKARVLIFANKQDLKGAMTASEISQQLSLTSIKDHGWHIQACCGLTGEGLYKGLEWM VSHLRRREIPIRRVQVNDPSQLPADYAQTPGGTLFSTTPGGTKIIYERKFLMKMQHSPLA KSPPPNLPEIPGVTSPPPAGKRKEIYKYEAPWTVYSMNWSVRPDKRFRLALGSFVEEYNN RVQIVSLDEETSEFTGRSTFDHPYPTTKIMWIPDSKGVFPDLVATSGDYLRVWRVTRLEC LLNNNKNSDFCAPLTSFDWNEVDPNLLGTSSIDTTCTIWGLETGQVIGLVSGHVKTQLIA HDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDHHHHPLLRLAWNKQ DPNYLATMAMDAMEVIILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQAL IWDIQQMPRAIEDPILAYTGAGEINQIQWSSTQPDWIAICYSHCLEILRVRNFSTTQKVA VLGASGGIGQPLSLLLKHQPLITHLALYDIAHTPGVAKDLSHIESPGEVTGHLGPESLEE CLTGCDVVVLPAGVPRKPGMSRDDLFDTNASIVRDLCDAAARYCPKALLAIIANPVNSTV PIASEVYKKHGVYDQNRIFGVTTLDIVRANRFVAEVKGLDASKVNVPVIGGHAGATIIPL LSQATPPVSFPPEEREKLIVRIQNAGTEVVEAKDGAGSATLSMAYAAARFTNSLLEALSG KSDVVECAFVRSEITEAKYFSTPLVLGRNGVEKNLGIGKILKYEVDLVDAAMPELKKSIE KGEAFAAK-IDRGKDFNIKTRIITDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFVS TLSHLRRLNSPIGRDGKLARPRQLHNTLWGMICPAETPEGQAVGLVKNLALMAYISVGSQ PSPILEFLEEWSMENLEEIAPSAIADATKIFVNGCWVGIHRDPEQLMNTLKKLRRQMDII VSEVSMIRDIRDREIRIYTDAGRICRPLLIVENQKLLLKKSHIDLLKDKEYNNYSWQDLV ASGVVEYIDTMEEETVMLGMTPDDLQEKGLGYCSTYTHCEIHPSMILGVCASIIPFPDHN QSPRNTYQSAMGKQAMGVYITNFHVRMDTLGHVLWYPQKPLTTTRAMEYLRFRELPAGIN TIVAIASYTGYNQEDSVILNESAVDRGFFRSVFYRSYKDSESKRGLDQEEIFEKPTRDKV ESMRPACYDKIEDDGIISPGIRVSGDDVLIGKTLSIPDNEDDLEATTKRFHKRDASVFMR RSEYGIVDQVMVTINHDGYKFCKIRIRTTKIPQIGDKFASRHGQKGTCGIRYRQEDMPFT CEGITPDVIINPHAVPSRMTIGHLIECLQGKVSANKGEIGDATPFNDAVNVQKVSNLLAE YGYHLRGNEVLFNGFSGRKMNSQIFLGPTYYQRLKHMVDDKIHSRARGPVQILNRQPMEG RSRDGGLRFGEMERDCQIAHGAAQFLRERLFEVSDPYRVHVCNICGLIAIANLRNHTFEC RGCKNKTQISQLRIPYACKLLFQELMSMSIAPRMMV-------GFSFENCQRNALLQKGL KPPTAYKTGTTIAGIIFKDGVVLGADTRATEDTIVADKNCEKIHYISDNIYCCGAGTAAD TEFTTQMISSKLELHRLDTGRKPRVCTANRMLKQKLFRYRGYISAALVLGGVDCTGPHLY SVWPHGSTDTLPYVTMGSGSLAAMSVFEARYKIDMERDEAMKLVRDAIAAGIFNDLGSGS NIDLCVITKKVEYLRTYDEANKKGVRAGSYRYKRGTTSVVKKEVKKIPFEVV--KVTFKI TLTSDPKLPYKVLSVPEGTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPDQSAGNVFL KHGSELRLIPRDRVG-MAFTFAALCYIIALILTAFLIFFAIYHIIAFDELKTDYKNPIDQ CNSLNPLVLPEYGIHMFYYVLFVLSGQLLTIILNTPLLVYHIHRYMNRPVMSGPGLYDPT SIMNADQLSKAQREGWIKLAFYLLSFFYYLYSMIYVLVSS-------------------- ----------------------TISPTLGFNIKTLEHRGFKLNFWDVGGQKSLRSYWRNY FESTDGLIWVVDSADRRRLDDCKKELSTLLLEERLAGATLLVFANKQDLPGALSDAEIRD ALQLDEIKTHHW--------------------------------HSKKKICYYYDGDIGN YYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATQEEMTKFHSDDYIKFLRSIRP DNMSEYNKQMQRFNVGEDCPVFDGMYEFCQLSTGGSVAGAVKLNKQAADIAVNWGGGLHH AKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY GEYFPGTGDLKDIGAGKGKYYAVNFPLRDGIDDDSYESIFAPVMTKVMETYQPSAVVLQC GADSLSGDRLGCFNLTLKGHGKCLEFVKKYNLPLLLLGGGGYTIRNVARCWTYETSLALG VEIANELPYNDYFEYYGPDFKLHISPSNMANQNTPEYLDKIKTRLFENLRMLPHAPGVQM TAIPEDGINDEENPDERISIRASDKRITGDMEFSDSEDDE--TKKDRQSYKRKRVMDSNF ECNICLDTARDAVISMCGHLFCWPCLHQWLETRPQRQVCPVCKAGISKDKVIPLYGRGNA SQEDPREKLPPRPAGQRSEPENNGGFPGFGFGFQVSFGIGAFPFGLFTSLHNFNDGRPAA PPPGSPQQEDEQFLSKVFLWIAILFIVWLLIAMYSIIYKEEQAHEDSIWTCAWGKSERDG VENIVTAAVDDIVKCWKWTGLELRHVLEGHQLGIVSVDINLNGTMVASSSLDSHIRLWDL ETGKQLKSFDAGPVDAWSICFSPDSRFLATGSHTGKINLFGIESGKKETSLDCKMKFTLS VAYSPDGRYIAAGSIEGTINIFDMTTGKLLEGHAMPVRALCFSSDSQLLVTASDDGHSKI YDVQHGNLAGSLSGHGSWVLNAKFSPDNAHIVTCSSDKTVKIWDAGSRQCIHTFYDHMDQ VWGACYNATGSKVVSVSDDRAIHVYDCPVETDEEFDARYEQFFSNPNIDGWDVRRGMNEL QGFDLVPEPRIIVAALKACRRINDHSLAVRYLEAVQFKCGNRKKVIWPYILQEITPTLEE LGISTPEQLGYDKPELAMPDVLDMVVRVRGLPWSATAEEIIEFMAGVNLPRGAQSVHLTY MRDGRPSGEAYVEVCSENDVHHAVKKHNNHMGKRYIEVFSATKSEMDWVVKRSGPNQDAV VRLRGLPFGCSKEEIAHFFMGLEIVPNGISFIQDQRGRITGEAYVQFVSPEIAEKSHEKH KQKIGHRYIEIFKSSMAEARHSYQSCTGFWVHMRGLPFQANEEDVIEFFCPLNPVHVEIH YNRGRASGEADVDFATAEDAKKAMAKNRDRMQHRYIELFFEDKDKPTQIRYSNITAAKAV SDAIRTSLGPRGMDKMIQSGTGDVTITNDGATILKQMQVLHPSAKMLVELSKAQDIEAGD GTTSVVVIAGSLLDASAKLLAKGIHPTTISESFQRAAAKCCTILEDMSTPVKLSDNDSLL KSASTSLNSKVVSQYSNILSPITVDAVMKVIDPATAINCDLNDVKIIKKLGGTVEDTELI DGVVFNGRAA--AGPSKVEKAKIGLIQFCLSPPKTDMENEVVVSDYTQMDRVLREERQYI LDLVKKIKKSGCNVLLIQKSILRDAVNDLALHFLGKMKIMVIKDIEREDVEFYCRSLACK PIASIDHFQPEMMASADLVEEVQTGSSKVVKVTGITNQGRTVCIIVRGSNKLVLEEADRS IHDALCVIRCLVKKRALIAGGGAPEIEIALRLMEYSHTLSGMEQYCFRAFAEALEVIPFT LAENAGLNPISTVTDLRNRHAHGEKTAGINVRKGAITNILEENVIQPLLVSTSAITLAAE TVRSIMKIDDIV---MILLEINNRYIEKTLSGIFKNA----KFERVDITVADFDGVLFHI SNPNEDKSKVRVSMSMNFYKQLQSHGADELLKREYGSYLTDPEPGFNITLLFDENLPADH EELVKKVGLLKRNCFASVFEKYFNFLDEHERAVINYRDDETLYVDAQKDRVTVIFSTLFK EYDDMVISKIFMQEFKESRRTAQQAPQVLFSHKDPPSELSGTDAKTGDNIGYITFVLERR HQARDNTINLIHTLRNYLHYHIKCSKAYIHSHMRAKTVDFIKILNRAKQTPKTAEKKTIM LTFCPCCANVLIVEEGPKCYRFSCNTCPYIHNIQRKIANRKYPKLKEVDDVLGGAAAWEN VDSTEETCPRCSHPRAFFMQIQTRSADEPMTTFYKCCSQSCGHRWR------MKDDERIF TNLYGRHDWKLKGAMARGDWYKTKEIVLKGHDWILKEISASGLRGRGGAGFPTGMKFGFM NKPDDGRPKYLVVNADEGEPGTCKDREIMRHDPHKLVEGCLISGRSMGARAAYIYIRGEF YNEASNMQLAINEAYEAGLLGKNACGTGYDFDVYMHRGAGAYICGEETALIESLEGKQGK PRLKPPFPADIGVFGCPTTVTNVETVAVTPTICRRGGDWFAGFGRERNRDVLMDFDDLVE NNTALGTAAIIVMNKSADVVDCISRLIDFYKHESCGQCTPCREGVSWMTKVMHRWVKGNA RPEELDMMWELSKQIEGHTICALGDGAAWPVQGLIRHFRPELEARFQAF----YTQEVVD EMNQQLNQTRSQRVRAAMFPETMEEGIQIPSTQLNADQPTAVQRLAEPSQMLKHAVVNLI NYQDDADLATRAIPELTKLLNDEDQVVVSQAAMMVHQLSKKEASRHAIMNSQPMVSALVR AMINTNDLETTRCAAGTLHNLSHHRQGLLAIFKSGGIPALVKLLSSNVESVLFYAITTLH NLLLHQEGSKMAVRLAGGLQKMVALLQRNNVKFLAITTDCLQILAYGNQESKLIILASGG PGELVRIMRSYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGMHLGHQSQRLVQN CLWTLRNLSDAGTRLESIEGLLQMLVQLLASNDINIVTCAAGIISNLTCNNQRNKVTVCQ VGGIEALVRTILQAGDREDITEPAICALRHLTSRHPEAEMAQNAVRLHYGLPVLVKLLHP PSRWPLIKAVVGLIRNLALCPANHAPLREHGALPRIVQLLIRAHQDTQRQSTGYVDGVRM EEIVEGTVGALHILAREGNNRAVIRGLNCIPLFVQLLYSPIENIQRVAAGVLCELAADKE GAEMMEQEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYRKRLSTELTSSLFRAD NMSSHLTWAIIRNNSAFLRKGASFTTEANNLKGKNSFKYNGLIHKQTFGVEAAKDGKGVV IVTKRGGRKPSKSMARVELKKDARRTFATISKTISKSKDRRGLKMAALRRASAILQSQKP VVAKKAHDEPYYCSQQINIPPELPDILKQFTKAAIRTQPRDVLGWSAAYFKAMSRGEVPP VKERLEMPVATQKTDTGLTPGLLRALNKQLGPKKVTNISLIEEKWKELALPKEKFDDLVR LGSFAGDVEWLKFFALASSTLGENLCDAMKLICEILTADPEGGAARIPFTLWKDLYKFLA SVDGEISQESIDEVCAHLQYDVDKQEGFVQPRNFLNPDCPKLSGQID---AAQLKEQVKA QIAVANAQELLQKMTDKCFKKCI----TSIDNSEQKCIAMCMDRYMDAWNLVSKTYSSRL QRE----MNRIFGRGKPKQPPPNLNDCIAGIDSRGESIQKKIANLDKELIKYKDQMKKMR DGPSKNMVKQKAMRVLKQKKMYEGQYEQLSNQSFNLEQANFGLQTVKDTKTTVDAMALGV KQYKKEFKNINIDKIEDLQDDLGDMTEQANEMQDILGREYGMPDIDDADLDAELDALGDE IGLDEDSSFLDEAMNAPSAPTSVPGADSMSSKDGVPVDEFGLPQI--------------P QLQNIVCTVNLGCKLDLKKIALHARNAEYNPKRFAAVIMRIRDPRTTALIFSSGKMVCTG AKSEEEAKLAARKYARIVQKLGFPANFXDFKIQNMVGSCDVKFPIRLEGLVLRHGQFSSY E-----GLIYRMVKPRIVLLIFVSGKVVLTGAKVRSEIYEAFNNIYPILKGFRK-SDEDD DQFVELGMESEPSRHQDCDDFHFLVLTPEEIVQHMVDCIKEVNQIVEIPATTTRILLNHF RWDKEKLMERYWDGDQDKLFAEAHVISPYKKCKETMCEICYLNYSSLMTGLECGHKFCTH CWAEYLTTKIMHEGMGQTISCAAHGCDILVDDATVMKLITESKVKLKYQHFITNSFVECN RLMRWCPAPDCGNAIKVAYYDAKPVTCLCGYTFCFSCGENWHDPVKCRWLKKWIKKCDDD SETSNWIAANTKECPKCHVTIEKDGGCNHMVCQHCKADFCWVCLGPWEPHGSSWYNCNRY DEDEAKKARDAQEKSRSALQRYLFYCNRYLNHMQSLKFEHKLYASVKTKMEEMQQHNMSW IEVQFLKKAVDVLCLCRQTLMYTYVFAFFLRKNNQSIIFEENQRDLECATEQLSEYLERD ITSDILVDIKQKVQDKYRYCESRRTVLLNHVHEGYEKDIWEYHDMATTDGKMPTTERIIK SVPFPPNHRLIMSEVYDSKTKPRPDVLKQHFILEGRVTEDVALRIINEGAAILRQEKTMI EIDAPVTVCGDIHGQFYDLMKLFEVGGAPQTTRYLFLGDYVDRGYFSISEKVYDACMEAF DCLPLAALMNQQFLCVHGGLSPEIHNLEDIKKLDRFKEPPAFGPMCDLLWSDPLEDFGSE KTPEHFTHNSVRGCSYFYSYAACCDFLQHNNLLSIIRAHEAQDAGYRMYRKSQSTGFPSL ITIFSAPNYLDVYNNKAAILKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVT EMLVNVLNICSDDELLTEGDDSFE----ARKEVIRNKIRAIGKMARVFTVLREESESVLQ LKGLTPNGILPIGALSGGRENIKSALSGFSPSHKISGFEEAKCLDKVNERMPPRKGFSPR GGGRGGDRGGRGG-GRGGFRGGRGGGRGGRGGMRGGAKVVVEPHRHDGVFIARGKEDALV TLNMVPGDTVYGEKKIAVETGTKTEYRAWNPFRSKLAAAILGGVDKIHMPPGSKVLYLGA ASGTTVSHVSDIVGPEGLVYAVEFSHRSGRDLINVAKKRTNIIPIIEDARHPHKYRMLVG MVDTIFADVAQPDQARIVAINAHNFLKNNGHIVISIKANCIDSTATPEAVFAGEVNKLKL EKIKPQEQLTLEPYERDHAVVVGVYRAPPKK--KNMMNDLAGRLSKGGKGLGKGVGLLAA AAGLAYGAAHSFYTVDGGHRAIIFSRIGGVKNDVYTEGLHFRVPWFHYPIIYDIRSRPRK ITSPTGSKDLQMVNISLRVLARPDAMQLPNMYRQLGTDYDDRVLPSIVNEVLKAVVAKFN ASQLITQRQQVSLLIRSELTERAKDFRLIVDDVSITELSFGKEYTAAVESKQVAQQEAQR AQLVVEIAKQEKQQKVVQAEGEAQAAKLIGEAITANPGYLKLRKIRAAQNIARTIANSQN RVYLNAGTLMMNINESDFDKNLE------------------------------------- -----------------------------------------QTAVLIETLRALGAHVRWA ACNIYSTQNEVAAALAEAGFPIYAWKGETEDDFWWSIEKSIAYENWQPNMILDDGGDATH LLLKKYPSIFSMVKGIVEESVTGVHRLYQ---PGKLTVPAMNVNDSVTKTKFDNLYSCRE SILDALKRTTDVMFGGKQVLV-GYGEVGKGCCAALKGLGAIVMVTEIDPICGLQACMDGF RVVKLNEVVKQIDI-----RNKNVVGREHLDRLKNGCIVCNMGHSNTEIDVGSLRTPELT WEKVRSQVDHIIWPXGKRIILLAEGRLVNLSCSSVPSFVVSITAATQ------------- -------LLPKKMDEYVASLHLPTFDAHLTELSDEQAKYLGLNKAGPFKPNYYRY----- --------------------------------LRDKATGQSKGCCFVTFYTRDAAMNAQR DLHNLKTLAGMQHPVQMKPADSEKKNVEERKLFVGMISKKCTENDIKVLFAPFGQIEECT ILRE-NGVSKGCAFVTYANKQSAQSAMKNMHHSQTMEGCRSPVVVKVADTQKDKELKKIQ Q--------LTAGTIGGIANCLSAQPLDTVKVKMQTFPGEYKNALNCLTQTFKKDGTRGL YAGTVPALENAVLFMFYGICQKAVMGAAFFAALALTPTELVKCRLQAISKHIAKTEGLRG FFRGFVPTVAREMPGYFFFFGAYETSRRLMTPPGKTPDEIGPKTVISGGFGGIAFWTSVF PADVVKSRAQIKEDGVKALYKGLGPSLVRSFIATGCLFFSYEYTKKFLE---NDFNRLSQ AIGSNIQKITQNVSSVQRMVGQIGTSRDSEHLREELHKIEHYTNQLAKDTNKQLRDMVNL SSEQRQRKMQREKLTDDFSKSLNNFQVALRKAAEKEKESIEDVNLQLIQEREESVKKLES DIIGLNDIFKELGMLVHEQGEVIDSIEANVENIHVQEGNTQLEKARDYQSSARRKKCILV LILLAILIVIGVIIGIVYGMVNVTKGVLVECDPAMKQFLLHLDEVNALGRKFIIVDLDDT HLFVSAEIVPTLQERIDDLMDSLSFPLGKKDGKGPSPQEAIQRLREIEEMLAKKSEFLEK KINEQNAVAKKRVALNALKKKHRFDKQLTQIDGTLSTIEFQREGLENASTNTEVFKAMDY AAQALKGAHQGLDIDKVQDVMDDIQDQHELSQEISNAISTPAGFDMDLDEDELNAELEEL EQEELDEQLLNVGELPAIPSSDDDDLRELEAWASSLQRFHNRVRQILMASGSTTFTKIVN KWNTALIGLMTYFREAVVNTQELLDLLVKCENKIQTRIKIGLNSKMPSRFPPVVFYTPKE LGGLGMLSMGHVLIPQSDLRWSKQTDVGITHFRSGMSHDEDQLIPNLYRYIMPWESEFID SQRVWAEYALRTDMIQALGGVEGILEHTLFKGTYFPTWEGLFWEKASGFEESMKYKKLTN ASKDIMDNTTTQKYWLDIQLRWGDYDSHDVERYARAKFLDYTTDNMSIYPSPTGLLVGID LAYNLHSAYGNWFPGCKPLIQQAMAKIMKANPALYVLRERIRKGLQLYSSEPTEPYLSSQ NYGELFSNQIIWFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSV WAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKG SELQLPFQACLKVEKFGDLILKATEPQMLLFNLYDDWLKTVSSYTAFSRLILILRALHVN NDRTKVILKPDKTTITEPHHIWPTLSDEEWIKVEVQLKDLILADYGKKNNVNVASLTQSE IRDIILGMEISAPSAQRQQIAEIEKQTKEQSQLTATTTRTVNKHGDEIISSTTSNYETAT FSSKTEWRVRAISATNLHLRTNHIYVSSDDIKETGYTYILPKNILKKFIIISDLRAQIAG YLYGVSPPDNPQVKEIRCIVMPPQWGTHQTVHLPHLLPGHEYLKEMEPLGWIHTQPNELP QLSPQDISTHARVMADNPVWDGEKTVIITCSFTPGSCSLTAYKLTPSGFEWGRQNTDKGN NPKGYLPSHYERVQMLLSDRFLGFFMVPAQGSWNYNFMGVRHQPNMKYELQLANPKEFYH EIHRPSHFLNFSSIEEGTDREDMFCCYTATRGNLKIDLNTKVICQGFTGKQGTFHCQQAI EYGTNIVGGVSPGKGGKTHLNLPVFNTVKEAKDATGATATVIYVPPVFAGKAITEALDAE MPLIVCITEGIPQQDMVKVKHQLKRQDKSRLIGPNCPGIIMPGECKIGIMPGHIHRKGRI GIVSRSGTLTYEAVHQTTAAGLGQTLCVGIGGDPFNGTNFIDCLEVFLNDPKTEGIVLIG EIGGGAEERAAEYLIEHNGPDAKPVVAFIAGLTAPPGRRMGHAGAIISGGKGGAEEKIEA LRKANVEVTMSPAQMGTTMRNFMEKLGKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXYERFVEVGRVAFIA YGPQRGKLCVILDIIDQNRALVEGPFTGIKRQSMNFKHLHLTSFTVIGPSAR-------- ----------------------------------------------------------KT CPLLLRVFCNTGHHNDLREYRKGNTPKNELQIYTWKDATLKELASLVKEVNPDARKKGTC FDFGIVFADSRQPLFRLRDIGRVFSGRRTADDNASLASRRFLIGDYIDIAITPP-GLGKT LQTISLLGYMKHYRNVPSPHLVIVPKSTLYNWVAEFKRWCPSLRAVCLIGDAATRAEFIR DTLMPGEWDVLITSYEMCIREKAVFKKFNWRYLVIDEAHRIKNEKSKLSDIVREFKSSHR LLLTGTPLQNNLHELWALLNFLLPDVFNSSDDFDSWFNTSTCLGDKDLVSRLHEVLRPFL LRRLKSEVEKALKPKQELKVYVGLSQMQREWYTKILMKDIDVVNGAGRSDKMRLLNILMQ LRKCCNHPYLFDGAEPGPPYTTDKHLVDNCGKMVLLDKLLPKLQADGSRVLIFSQMTRVL DILEDYCFWKEYDYCRLDGQTPHEERQKSIDEYNRPGSNKFIFMLSTRAGGLGINLATAD IVILFDSDWNPQVDLQAQDRAHRIGQKKVVRVFRFITEHTVEERIVERAEMKLRLDNIVI QQGRLVDQN-QRDVLQMIRHGADHVFAAKDSMITDESIDEILNRGKMRTEEDKKKLEELG ESSLQKFTLDTPTDSVYKFEGQDYRDKQKL-SVTHWIEPPKRERKANYAVDAYFREALRV SEPKAPKAPRPPKQPNVQDFQFYPPRLFEILDKEIYFYRKTIGYKVPRNPELGSEADKVR KEEQKRIDDSEVLGEEEQNEKEELLKGFTNWSKRDFNQFIKANEKYGRDDLDSISRDVEG KTPEEVMEYASVFWDRCNELQDIERIMAQIERGEAKIQRRAGIKKALDAKMARYRAPFHQ LRIQYGTNKGKNYTEEEDRFLVCMLHKLGFDKENVYDELRSAVRQAPQFRFDWFIKSRTA MELQRRCNTLITLIERENMELEEKEKAERRK----------------------------T NTRTITEYKLNEDGKRVRIVKTYKIETRKVSTSIAKRKQWKKFGAATHDPPGPNPANTVE D-----------AEEDPLAKMKVSCRICKGDHWTTKCPYKDTLSPLADAL---------- ------------------------------------------------------------ -------------------------------------MSETYDFLFKFLVIGSAGAGKSC ILHQFIENKFKQDSNHTIGVEFGSKVVNVGGKSVKLQIWDTAGQERFRSVTRSYYRGAAG ALLVYDITSRETYNALTNWLTDARTLASPNIVIILVGNKKDLEDEREVTFLEASRFAQEN ELMFLETSALTGENVEETFLKCARSILTKIESGELDPERMGSGIQYGDASLRRLTQKRPD CSC-VDPEAKVKLETSQWPLLLKNYDKLNVRTNTYTPIPSGCSPLQRPIAEHVKAGFINL DKPSNPSSHEVVAWIKRILRVEKTGHSGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYV CVFSLHSVVDDKKQVLKAIESLTGALFQRPPLISAVKRQLRIRTIYESKLLEYNKDMKMG IIWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGIQSEKEGMVTMHDVLDAQWMYD HQKNENYLRRVIKPLEALLTSHKRIIMKDTAVNAVCYGAKIMLPGLLRYEDGIELNDEIV VVTTKGEAIALAVAQMTTAVMATCSHGIVAKIKRVIMERDTYPRKWGLGPHASKKKDLIA KGLLEKSGKPNERTPANWKNIYPE------------------------MAEVGWDRKKAP KSTALKSQRAINAAQRSGAEIKTDKKFSAAQNKQSTAAKDTAKLDRETEELHHDRVSMGV AKHIQKRRSELKMTQKDLSTKINEKPQVVNDYEAGRAIPNPQIMGKLERALGIKLRGKDI GLPLH--MLRPRALTQVLSQANTGGIQYTLLLNGEGALLAFAGFGDKDARVTAAIASGIW AAYEKSGAVAFNEDKLQVVLLECEEGRVVITKVASLLLCIYAKEDVGFGLLRAKATALAE YLEEPLTQVATSSGVTARINPKKQTLEDAYSAPANFLEIDVKDPQGNKRYTDYEIKLQTN LPVFRAKESSVRRRYSDFEWLRTELERDSKIVVPPLPGKALKKQLPFRGDDGIFEDEFIE ERRKGLEGFVNKVAGHPLAQNEKCLHMFLQEHVIDKNYVPGKMRTT-----RLVEVGVFE EPKLQGKYETGQVLLHKVFGYRGIVLFPWVAKVYDKDIKMNLNKETRAQSQTYYQVLIDS RDCPFIRAQSEAVTFLGNQENRSLYAIPGLDYVGHEDVLPYNSTEKHPIKHELFEKFLIH DPPFIARETLRAWQEKNHPWLELSDVHRQTTENIRVTVIPFYMGESQQSQIYLWRYCIRL ENLSDQTVRLRERHWKIYSLTGTLETVRGRGVVGQEPSLSKKQPAFQYSSHVSLQAPSGH MWGTFEMEREDGTTFQCIIPPFLLESK----MATSKGANTYNRQNWEDSDFPSLCQTCLG DNPYIRMTKEKYGRECKICARPFTVFRWCPGARMRFKKTEVCQTCSKIKNICQTCLLDLE YGLPVQVRDAALRIADEMPKSDVNKEFYTQNIETQLANQEEG-SVGLLGKAQTPSDMLLK LARTTPYYKRNRPHICSFWVKGECKRGEECPYRHEKPTDPEDPLADQNIKDRFYGMNDPV ADKLLKRYSHMPKLEPPEDMDVFIIIRRKKVTIFADAKESTTVYELKKIVEGILKFQPED QILYKDNKTLGDCGFTSSLARAQSPATIGLAVKKVEGLEITALSTPPELPDVMKSQEGAS SLSQD--FRYHAVLLRARFDENRN-DPNEAVRLLHAGEKELWDKQHPQPLKFPNSPGGVA FGREAYTPDSMLDAWHPLEKAQYPEYFARRDQRKKEYIERWEKKYGKVEMEDYVKIEKIG EGTYGVVYKGRNRKTNRLVALKKIRLESEEEGVPSTAIREISILKELQHPNIVSLDDILM QDGKLFLVFEFLQMDLKKYIDTIPSDQLMDKMLVKSYLHQLLQGILFCHKRRILHRDLKP QNLLIDNKGVIKLADFGLGRAFGIPVRVYTHEVVTLWYRAPEVLLGSQRYSCPLDVWSIG CIFSEMATKKPLFHGDSEIDQLFRIFRTLSTPTEDIWKGVTSLQEYKSTFPNWKTNQLET AVSAAGFDLLQLTLIYDPAQRISAQAALKHPYF---IFNTVGKLGLGLAVVGGVVQSALY NVDGGHRAVIFDRFRGVQPNVIGEGTHFLVPWVQRPIIFDCRSRPRNIPVVTGSKDLQNV SITLRILFRPKIDQLPKIYMNLGEDYDERVLPSITNEVLKAIIAQYDASELITQREHVSQ KTREVLCDRGASFGLIMDDISLTHLAFGREFTAAVEMKQVAQQEAERARYNVEKAEQQKR AAIIAAEGDSKAAELLAKALGDSGDGLVELRKIEASEDIAYQLSRARGVVYLPTGQSTLL NLPMKTIRLNETVKIPKGIEVTIKARRVTVKGPRGVLRRDFKHAYIEMSKKG-NIILVEK WFGTRKELAAVRTVCSHIQNMFKGVTKGFQYKMKSVYAHFPININISENGSMVEIRNFLG ERFNRRVSMAKGVLCRLS-GVKDEIILEGNDIEDVSHSAALIQQSTTVKNKDIRKFLDGV YVSEKTTVVQEMGCAVSSEDRIAIERSKQIDKTLREDGEKAAREVKLLLLGAGESGKSTI VKQMKIIHEKGYSKDECLQYRPVVYSNTIQSMIAIIRAMGQLKIDFGQPERADDARQLFA LAGNADDGELSSDLADVMKRLWFDPGVQHCFSRSREYQLNDSAAYYLNELDRISQPGYIP TEQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFIVAMSE YDLTLAEDQEMNRMMESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICFPE YGGPNTYEEAASYIQVQFNKRKDTKEIYTHFTCATDTNNVQFVFDAVTDVIIKNNLKDCG LFKKFAARKRLINLKDSRIKQEHREFKRAKKVDPRTLKIRELPQSSSAMFFQYNTQLGPP YHILIDTNFINFSIKNKLDIVQSMMDCLYARCVPYITDCVMAELEKLGAKYRVALRIAKD PRFVRLPCMHKGTYADDCLVQRVTQHKCYIVGTCDKDLRRRIRKIPGVPIMFLQQHRYSI ERMPDAFGAPKMSFSSDEVNFLVYRYLQESGFAHSAYTFGIESHISQSNINGALVPPAAL LNIIQKGLQYTEAEISIGEDGSERVIESLSLIDAVMPDVVESRKQAAQKNTNGDDHNDAM EIDGTTEIPSSKATILRGHESEVFICAWNPTNDLLASGSGDSTARIWNMNDNSNANQLVL RHCIQKGGTEVPSNKDVTSLDWNCDGTLLATGSYDGFARIWSTDGRLVSTLGQHKGPIFA LKWNKKGNFILSAGVDKTTIIWDASSGHCTQQFAFHSAPALDVDWQSNTSFASCSTDQCI HVCKLGVDKPIKTFQGHTNEVNAIKWDPQGNLLASCSDDMTLKIWSMKNDTCVHDLQAHM KEIYTIKWSPTGPGTNNPNAPLILASASFDSTVRLWDVDRGVCIHTLMNHQEPVYSVAFS PDGKYLASGSFDKCVHIWNVQSGALVHSYRGTGGIFEVCWNHRGDKVGASASDGSVFVLD LRKNGNDLASLFECPVCFDYALPPIMQCQSGHIVCSSCRPKLSSCPTCRGPLGNIRNLAM EKVASTVMFPCKYVSTGCPVTLLHTEKGDHEEGCEFRPYSCPCP---------------- ------------------------------------------------------------ -----GTRKQAENFAYRLELNGHRRRLTWEATPRSIHDGVQVAIANSDCLVFDTNIAQLF ADNGNLGINVTIS-----QSFFQEYVQIPPITRAYCTACVMTTLAVQLEVLTPFHLYFNP ELIFEKGQLWRLVTNFTFFGTVGFNCLFHMIFLYRYCRMLEEGSFRGRTSDFVFMFLLGG TMMIVVVNIVFLGQAFTMMIVYIWSRRNPYVRMNFFGLMNFQAPYLPWVLLAFSFLLGNV ITVDLMGIAIGHIYFYLEDVFPEQPGGFKILKTPHFMKVLFDGLHEDPNYNVLPPGGYDW DGGLELLSDQGLRIDGRRPHELRRIQCKMGVFRQADGSAYIEQGNTKILCAVYGPHEVR- NRSKNDKVLINCQYSMATFSTGERKRRPRGDRKSQEMTMHLQQTFEAAVMTHLYPRSQID IFVEVLQADGGNYCASVNAATLALIDAGIAMQDYVCACSSSYLKDQTIVDMNHLEESSSP ELIVALLPKSEQMAFVEMNGKMHEDHLNNTMEMAMKGCRDIYSVLDRAVREMSGTYYFVI VGHYDNPVFEMEYAPANRTSDPKKDDHRHLNQFIAHAALDLVDEMMWTTSNMYLKIVDKF NEWFVSSFVTAGRMRFMMLHDVKNEDGIKNFFAEMYESYIKLTMNPFYEINTPVHSAAFE KKAQTIGKKYLSMQVRYAHTDIQVPDFSAYRKESTMTVRKSFTYLVTAGSGVAGLYSAKT VAHEFISTMSASADVLAMAKIEIKLSEIPEGKSVTFKWRGKPLFIRHRTSEDIERENAVN LSELRHPEHDNERTKNPEWLVLLGVCTHLGCVPIADAGDFGGYYCPCHGSHYDGSGRIRK GPAPLNLEVPEYTFVDEDLLVVGMSRQTNRYGDPRKVSAELFTLTYGALVAQLMKDYEND DEVNKQLDKMGYNIGIRLIEDFLARSNSGRCHDFRETADVIAKVGFKMFLGITPAIANWS AAGDEFSLLLENNPLTDFVELNDKHSGLNYSNLLCGVLRGALEMVQMDVDVRFVQDQLKG DNITEIRLKFIKRLEDAVPAGEDENVKQFLQQAREDFEEKWGKPAQNTASLDEFERIKTL GTGSFGRVMLVQHKQNKEYYAMKILDKQKVVKLKQVEHTLNEKRILQAVSFPFLVNLEYH FKDNSNLYMVLEFVTGGEMFSHLRRIGRFSEVHSRFYAAQIVLTFEYLHHFDIIYRDLKP ENLLIDNHGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVY EMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNAVQ DIKNHKWFSTTDWIAIYQRKVEAPFIPRCKGPGDASNFDDYEEEPLRISSTEKCAKEFAD FMFADTFLILFISICTALLGEGLTWLMVYRTDKYKKLKAEVDKQSKKLETRKERTGESQD RSLKKKIERQEEKLKNHNRDLSLVKMKSMFAIGFAFTALLSMFNSIFDGRVVAKLPFVPI SWIQGISHRNLMGDDFTDCSFIFLYILCTMSIRQNVQKLLGFAPSRAANKQSG-LFSPCT KYFDTWSENDQVEFVEHLLSRMCHHQHGQINCFLKPMLQRDFISALPSKGLDHVAEKILA YLDAKSLCSAELVCKEWHRVISDGMLWKKLIEHMVRTDSLWAGLAERRGWIQYLFRPKPG EPPKDHRFYRKLYPQIISDIQKIELNWKMGRHTLQRIHCRSETSKGVYCLQYDDQKIVSG LRDNTIKIWDRSSLECVQVLTGHTGSVLCLQYDENIIVSGSSDSTVRVWDVKTGEMMNTL IHHCEAVLHLRFCDGIMVTCSKDRSIAVWDMQSPREINLRRVLLGHRAAVNVVDFDEKYI VSASGDRTIKVWNTSSCEFVRTLSGHKRGIACLQYRDKLVVSGSSDNTIRLWDIECGACL RVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPAGTLCLRTLVEHSGRVF RLQFDEFQIVSSSHDDTILIWDFLNMAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNS TFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNQKS FDNIRNWIRNIEEHASADVEKMILGNKCDMNDRRQVTKERGEQLAIEYGNKFMETSAKTS INVEESFFSLARDIKTKMDRKL----SSADKNVEMWKIKKLIKSLEAARGNGTSMISLII PPKDQISRVSKMLADEYGTASNIKSRVNRLSVLGAITSVQQRLKLYSKVPTNGLVIYCGT IVTDEGKEKKVNIDFEPFRPINTSLYLCDNKFHTEALTALLADDNKFGFIVMDGNGALFG TLSGNTREVLHKFTVDLPKKHGRGGQSALRFARLRLEKRHNYVRKVAEVAVTLFITNDRP NVAGLVLAGSADFKTELGQSDMFDPRLHAKVLKTVDVSYGGENGFNQAIELAADTLANVK FIQEKKLIGRYFDEISQDTGKYCFGVDDTLKALEMSSVETLIVWENLDITRYTLKNHAND EEKVLFLRKEQEKDKTYFQDKETGVELELVDSMPLLEWFANNYKSFGATLEIITDKSQEG AQFVRGFGGIGGMLRYQVDFQSMEFIDDDDELYDLDDYITRSAQPLVGKRSKDDERYIQM IMDANAQSHKLYILDARPSVNAVANKAKGGGYENEDSYSNVELVFLDIHNIHVMRESLRK LKDVVYPNIDDAHWLTSIESTHWLEHIKQILAGAVKIADKVESNKTSVLIHCSDGWDRSS QLTALAMLMLDPYFRTIKGFEVLIEKEWLSFGHKFGLRVGHGEDKHTDADRSPVFLQFID CVWQMTKQYPNAFEFNEHFLITILDHLYSCLFGTFLFNSDMLRTKEEVKTRTVSVWSYIN SDIEEYMNPLYQHVLLPVASLRRIELWTRYYIRWNPRMRPQEPIHLRNRELLLLKAQLQK RLEELQRSLDQK-PPFRPFIPHVPFDLTQCEASFPRAKTANEEKALTDALLKRNTDLTPA ASHQTNLLNLVTKITSVVDALIVSPANFEAAQIEEIRQVGSHKKATMMVGHNVADVVVVL KTLPTLEAVAALGTKTLEDLKSAEPHEVITMMPNDSGFEISSPDATVKVLIATIPPNMKK LDPELHLDVKTMNRHLAAMRHARWFEENASHSSIKVLIRLLRDLRNRFDGFEPLNPWIID LLAHYSVMNNPSRNPLAVNVAFRRSLQLLSSGLFLPGSAGINDPCESGNSRVHTCLSLEQ QDQVCYTAQTLLRVLAHGGYRQILGMEGNASIATEMSVWEGVVVTPSDKAYEKLD-VVRL IEQYLKENNLFRTLSILQEESGISLNTVDSVDSFVSDINNGHWDTVLQAIQSLKLPDTKL IDLYEQIVIELIELRELGAARSLLRQTDPMLMMKSTQAERYVHLENMLARSYFDPREAYP EGQTKERRRAAIAQALSGEVNVVPPARLLALLGQALKWQQHQGLLPPGTTIDVFRGKAAV REQEDEKYPTQLNRTIKFGQKSHIECAKFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLK YQAQESFMMMDDAVLCMCFSRDSEMLATGGQDGKIKVWKIQTGQCLRRYEKAHTKGVTCV NFSKDSGQLLSASFDQNIRIHGLKSGKILKEFRGHSSFVNDVVFAPDGHHIMSASSDGTV KVWSIKSTECTNTFKSLGGTGTGDTTVHSIHPVPRNVEQFVVCNRSNIVAIMNMQGQIVR SFSSGKREGGDFVSCTLSPRGEWIYCVGEDMVLYCFSVTTGKLERTLTIHEKDVIGIAHH PHQNMIATFSEDGLLKLWRPMAQKVAKGPKLVTFAKPRLQTFWKYAKVEMMPPAEFPQVQ QGFQNLIKAKNGKWKTVTVKEGACITAEIFFWFFAGEVIGRGSLLGYAIPGAVHYD--AI PRFYYKLPSEDETLLQKLREESRAVFLQRRSKELLDNEELQGLWFLLDKHHTPPLVGDEQ MINYADFLKVGDKAGIKCRPFFTATVFAKLLQNDPYGRISIMQFFNYVMRKVWLHQTRIG LSLYDVAGQGYLKESDLENYILELIPTLPQLDCLEKSFYSFYVCTAVRKFFFFLDPLRTG RVKIQDILACSFLDDLLELRDEELPKEVQESNWFSAPSALRVYGQYLNLDKDHNGMLSKE ELSRYGTGTLTAVFLDRVFQECLTYDGEMDYKTYLDFVLALENRKEPQALQYLFRILDVQ NRGYLNVFALNYFFRSIQEQMRAHGQEPVSFIDVKDEIFDMVKPADPLKIALLDLINSGQ GDTVVSILIDLNGFWTYENREAEVVKGQIFEVGPRYYDLTYIGEGAYGMVVSATDMKTSQ KVAIKKISPFEHQTYCQRTLREIKILTRFKHENIIDIRDILTTRRIDEMRDVYIVQCLME TDMYKLLKTQKLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFG LARVADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDVWSVGCILAEMISNRPIFP GKHYLDQLNHILGVLGSPSQEDLQCIINDKARGYLQSLTYKPKVPWVRMVDSKALDLLDK MLTFNPHKRITVLEALAHPYLDQYYDPADEPVAETPFTIDMELDDLPKEKLKELIFEET- --------------------------------------------------DPAGDNLYLG IVLTAVVVVTGCFSYYQEAKSSRIMESFKDMVPQFALVIRNGEKINIRAEDLVVGDIIEV KFGDRVPADIRVISASSFKVDNSSLTGESEPQVRTPDFTNENPLETRNLAFFSTNAVEGT CTGIVVKTGDKTVMGRIANLASGLEMGETPIAREIAHFIHIITGVAVFLGVSFFVIAFIL GYYWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTI CSDKTGTLTQNRMTVAHMWFDNRIVEADTSDDQSNATYDKDNQSWNALARIAMLCNRASF KVGQEGVPVLKRECNGDASESALLKCVELSIGHVSEYRETNKKVSEIPFNSTNKYQVSIH VDG--YLLVMKGAPERILDRCSTILMDGKDIALDEKWRDTFNVAYMELGGLGERVLGFCD YVLPRADYPDGYPFDPDEVNFPLTGLRFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVT GDHPITAKAIAKGVGIISEGNETVEDIAARLGIPVSEVNPRDAKACVVHGSDLRDMTPAQ IDDVLRNHTEIVFARTSPQQKLIIVEGCQRQGSIVAVTGDGVNDSPALKKADIGVAMGIA GSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLLFILAD VPLPLGTITILCIDLGTDMVPAISLAYEFAESDIMKRKPRDPLHDKLVNHRLIGMAYGQI GMIQAAAGFFVYFVIMCENGFWPSRLFGIRKEWDARGINDLEDSYGQEWTYHQRKTLEYT CHTSFFVSIVIVQWADLIICKTRRNSLFQQGFKNHHMTFGLIFETVLAAFLCYCPGLDKG LRMYPLRFTWWLPALPFSLSIFIYDECRKFVLRRNPGGFIETETYYTFRNLSKGKKLLLG VAVGGAGVALALNELTLHPPKLPWSHNGLFQSFDHASIRRGYEVYKQVCAACHSMQYLHY RNLVGVSHTEDEAKAEAAEVMIKDGPDEEGNMFERPGKLADRFPAPYANDEAARAANNGA LPPDLSYITLARHGGEDYLFALLTGYVDPPAGVSLADGQHYNPYFPGGAIGMAQALYNEI IEYEDGTPATLSQLAKDVSTFLSWASEPEHDVRKRMAIKLLLVFLILGSYYVKRHKWMVL KSRKIAWENPGAPSTCKWALGKINESPHNHLTRKPKIYPNILHQIGETPLVRVNKLAKSS GIKCELLAKCEFFNAGGSVKDRIAMRMIEDAEASGRLKPGDVLIEPTSGNTGIGLALSAA VKGYRCIIVMPEKMSMEKVNILRALGAEIVRTPTSASFDSPESHIGVSQRLLKEIPNSHI LNQYCNPSNPLAHYDGTAEEILEQCGGKLDMLVAGAGTGGTISGLARKMKEKCPECKIIG VDPHGSILAEPEETTYYDVEGIGYDFIPQVLDRSNVDAWYKSEDKASFLMARHLMRDEGF LCGGSSGSAMDAAMRAIKDYGLKEGQRCVVILPDSIRNYMSKFLCDEWLQERGFMSDLGS EEEQGPYLGEYDGERNENEERHGHGKATLPNGDTYEGMYENNKRNGQGTYRFKNGARYIG EYMKNKKHGQGTFIYPDGSKYEGSWVDDQRHGFGKYTYVNADYYEGEWQSHLRHGQGVYL YSETGSKYSGTWKEGKQEGHGELIHANHKYVGVFKDGRMDGKGKYVFDIGCQQHGEYIMP DIMRLITKDLSEPYSIYTYRYFIHNWPKLCFLAMDGDITIGAIVCKLDLHKKMVRRGYIA MLAVDSNYRRRKIGSQLVLKAIKAMVADECDEVVLETEITNKAALHLYENLGFVRDKRLF RYYLNGVDALRLKLWLR----------ANNKKCLKEEIHKDVLVSGDYEFQEMPGQKGSI HITDSKSHTLFKKEDASKGKFAFTTEEYDMFQVCFETKMIAGGQGADREVFIDMKHGVEA KDYGNLAKAEKLKPLEVELRRLEDLSESIVNDFAYMRAREEEMRDTNESTHSRVLYFSVF SMCCLLGLATWQVLYLRRFFKAKKLIE--------------------------------- ------------------------------------------------------------ ---------------------------------------------------------SER ICPIFQVSNVSGKNLSLLKMFMNLLSTRIASEPPEFQIDDTFSVPGVGTVVSGTCLRGTI QLNDVLLLGPDALGHFQTIVIKSIHRKRMAVKMVRGGQTASFSLKKNQIRKGMVMVSPKI DPKACWEFEGEILVLHHPTTISVRYQAMVHVGSVRQTATIMTMTEEHLRTGDKATVRFRF IKNPEYLRTDMRMVFREGRTKAVGTITKLFPHISANTRQQRSGKKLHQQEKLEQTDHHHF YLFKVLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASGEELHTLEGHRNVVYAIAF NNPYGDKIATGSFDKTCKLWSAETGKLYHTFRGHTAEIVCLSFNPQSMVATGSMDTTAKL WNVVCTLSGHSAEIISLAFNTTGNQMITGS--NTVCLWDTIVHTLIGHKAEISSAQFNWD SSLIATGSMDKTCRLWDPKDGRCVGTLHGHDDEVLDVTFDYTGKYLLTASADRCYDATTH SKMEGHEGEISKIAFNPQGTMVLTASADKTARLWNYETGECLHILQGHTDEIFSCSFNYE GTTIITGSKDNTCRIWRGDVFLEKHWKSVIHRSICDYFFEAQNKAACNDDVPPVIATPHH YLINIHRNHMFVVAVVTTEVPPLFVIEFLHRVMDILEDYFEEATESVIKENYVIVYEILD EMLDNGFPLATESNILKELIKPPNLLRQIASTVTGKSNNVSATLPTGQLSNVPWRRTGVK YTNNEAYFDVIEEIDAIIDKSGSTVCAEIQGYIDCLIKLTGMPDLTLSFMNPRLLDDVSF HPCVRFKRW---------------------------LQIPFFHR---------------- -GP--------------------ILNYDASPCHGNLLISPDRKILVWNIGQKFPSKNPEI ------------------------------------------------------------ ----MATAIKTSTRYSVPDWYTSNHAISTNAERQRGTSHDVRQSARKLRNETDNKTKWDQ YDNNTRLADRVDDIRKWKEILERCLANIDREIADLSEAKDLTEQALEDKNLPLDVAIECQ TLREGRQGIDLVNDKVQSELGNEVNVIEGIKGALQQKIDESFEQLCLLQEARQQIVADLR DKNIALGIDIDQYNLTEKSPGISYKPDPCRVPKGSTTPQQWEDFSRINKERAEAEMRTST TLREAIHHTLQKTANDLEAQKEHLNYEYRKRIREMEAAKKELEWQKENTEKEIKDLRGDI AALEESIQARIPPSKLAQTRLENRTYRPNVELCRDRPQYGLTDEVKQLDVTKKALEEKLR EARYQLDGLEDNLHKIDDDLALKTNSLMLDKRCLDVREKLERNLGLTGMCGLKGELSNLI PDHQKKVKEFRAKHGGTKIGDITVDMTYGGMRGMKGLVCETSVLDPEEGIRFRGYSIPEC QQLLPKAADGAEPLPEGLFWLLCTGKVPTDEQVKLVSQEWASRASIPQHVVQMLNSFPNN MHPMSQFSAAITALNTESKFAKAYSDGVSKASYWEYAYEDSMDLIAKLPTIAALIYRNLY RDG-KVCAIDDNLDWSANFAKMLGYDSPMFTELMRLYLTIHSDHEGGNVSAHTCHLVGSA LSDPYLSFAAGMNGLAGPLHGLANQEVLVWLMKVKVTDETMKEFIWKTLKSGQVVPGYGH AVLRKTDPRYTCQREFALKHLPDDPMFKLVSTIYKHAPTILTEHGKAKNPWPNVDAHSGV LLTYYGMTEMNYYTVLFGVSRALGCLSSLIWSRALGFPIERPKSMSTDGLMKFVKMPWKP PVVEKCPGCNKAVYAAEERLAAGKKWHKQCLKCGMCNKYLDSTTTSEHEGKVYCR----- ------------------------------------------------------------ ----------------------------------MFNREPVGKYHVQICTTTPCMLGGVG CAPILEAIEKNLGIKPGHTTEDKMFTLSEVECLGACVNAPMVQINDNYYEDLTVKDMEEI LNDLKAGRVPKAGPRNG---RFASEPLAG-------------------MQKYEKLEKIGE GTYGTVFKAKNRETHEIVALKRVRLDEEDEGVPSSALREICLLKELKHKNIVRLHDVLHS DKKLTLVFEYCDQDLKKYFDSCNGEIDPDAVKSFMYQLLRGLAFCHSRNVLHRDLKPQNL LINKNGELKLGDFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAGCIF AELANAGRPLFPGSDVDDQLKRIFKLLGTPTEDNWPGMSQLPEYRPFPLYHVSQQVVPKL NSKGRDLLQHLLVCNPPKRMSAEEGMQHTYFADLNPAIK-DDKF-VDNKPDPRVRYPLTG EC-SMPIEYCEYSANYEECKKWLAENLPAEFEKLSAKRQTRGGKGVNKSKKKVAPQKICL FRTSRAKKKWTTVITGLSSNEIDIKKASKKFAQKFSCGSSVTGDDEIVIQGYFKDDLWDY VIEEF-KIDEDNMDDLGDKSKYYSVDRTSQSMILKSQQCGHPDAKNTLLYGCPDNYRNWY IYSPVLGGLSTVNPHGFSSVHVPDKETLVTDAGKLHVLDSLLGRLKCEGHRVLIYSQMTR MIDILEEYMWHRRHTYIRLDGSSKISDRRDMVADFQARSDIFVFLLSTRAGGLGINLTAA DTVIFYDSDWNPTVDQQAMDRAHRLGQTKQVTVYRLVCKGTIEERIIQRAKEKSEIQRMV ISGGTFRPDILKPKEVVSLLLDDDEM---MSLETVPKDLRNLRGCLLCSLVKTFEQFEFD GCDNCEEYLRMKSNRDAVYECTSNNFDGL------------------------------- -------------------------RYVCALSQEQKKELADIANRIVAPGKGILAADEST GTMGKRFAQINVENTEDNRRHYRQLLFSAIAENISGVIMFHETFYQKSDGGVPFPKMLKD KGIITGIKVDKGVVPLAGTHGESTTQGLDGLSERCAEYKKHGADFAKWRCVLKIGPHTPS HQAMIENANVLARYASICQQNGLVPIVEPEVLPDGDHDLDMAQNVTEEVLSYQYRALNEH NVFLEGTLLKPNMVTAGHGCPKKFSHVQNAMATVQALQRTVPAAVAGITFLSGGQSEEDA TVNLDAINKKPWALTFSYGRALQASVLQAWQGKKEQVAAGQKELLNRAKANGDAAMGKYE GGVSSAGSKSLFIADHKYYIQSLPKPVKRRVKALKKMQFETMKLEAQFYEEVHQLECKYA ALYDPYFLKRKEVVTGAVEPTDSDCDWPSDEEEEDD-AAIEDEENPNGIPYFWLTVFNNV EMLADMVQEHDRPIINHLQDIRVKHQIGFTLEFVFSANDYFTNKILTKQYTLRVGPDDDD PFIYEGPEIIKCTGCTIDWKKGKNVTKKTVKKTQKHKNKGTIRQVTKQVQNDSFFNFFNP PTAPEGELDEETETLLAADFEIGHFIRERIVPRAVLYFTGEALEEEDDGDDEDED----- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------LSSKLVAHQKDFFAKMVVDAVMMLDDLLP LDMIGIKKIQGGALEDSMLVDGVAFKKTFSYAGFEMQPKKYINPKIALLNVELELKSEKE NAEVRVDNVEDYQSIVDAEWNILYEKLEAIYKSGAKVVLSKLPIGDVATQYFADRDLFCA GRVVEEDLKRTLKACGGSIQTSVQNLKLGACELFEEVQIGGERYNLFKGCPEAKTCTLIL RGGTEQFIEETQRSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLREHSRTIPGKEQLL IGAMAKALETIPRQLCDNAGFDATNILNKLRQKHAGIWYGVDVNNEDIADNFVACVWEPA VVKINAITAASEATCLILSVDETIKNPKAQEGGAPQGRGRGRP-XXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXMPNIKVFSGTSHPDLAQKVCLRLGIEVGKVVTKKFSNQETCVEIGESVRGEDVYIIQ SGAGEINDMLMELLIMINACKIASACRVTAVIPCFPYARQDKKDKSPISAKLVANMLSVA GADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKDNITEWRDSCIVSPDAGGAKRVT SIADRLNADFALIHKERKKANEVASMVLVGDVKGRVAILVDDMADTCGTICLAAEKLVEA GATKVYAVCTHGILSGPAISRINNSIFEAVVVTNTIPQDAKMEAASRVQCIDISMMLAEA IRRTHNGESVSYLFSNVPLLSCRFYEHRFPEIEDVVMVKVRSIAEMGAYVHLLEYNNIEG MILLSELSRRRIRSINKLIKIGRNECVVVIRVDKDKGYIDLSKRRVSAEEVEKCEEKYAR AKAVNSILRHVGELLNYTTNEELEELYKKTAWCFDRKYGKPGASFDAFKNSVANPEALDE CDIDAETKRILLQNIKRRLTPQAVKLRSDINVSCYGYEGIDAVKLALRKGLSFSTEDIPI KINLIAPPLYVMTTQTIERQEGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMLGNLQTDMNKQGVSTVPKGHCAACNKP IVGQVITALGKIWHPEHFTCYQCQNELGTRNFFERDGLPFCETDYHTLFSPKCAYCNRPI LDKCVSALDATWHPEHFVCAQCGRPFEDGDFHEKNGKPYCRDDYFEMFAPKCGGCIQPIM DNYISALNKQWHPECFICQDCHMPFSGGSFFEYEGLPFCETHYHAKKGSLCAGCNKPITG RCITAMYRKFHPEHFVCAFCLRQLNKGTFKEQNDKPYCHACFVKLFMRPLTDEETRNFFE KLSKYIGENIKLLIDREDGTYCFRFHKERVFYVSEFILKKAAHVAREELLSFGTCFGKFT KTGNFRLHITALDFLAPYAKFKIWVKPSAEQQFLYGHHIMKSGLGRITENTPQYQGLVVY SMNDIPLGFGVAAKSTQECRHTDPMTIVAFHQADIGEYLRSEETISTERQFFVGGNWKMN GTQKSIDDICNFLHGDDSKTEVVVAPPTIYLSYVQSKLVGVSAQNCYKVEKGAFTGEISP AMIKDTGCQWVILGHSERRHVFGEPNELIGAKVAHALSAGLNLIPCIGEKLEEREAGKTE DVCFTQLKATDWSRVVIAYEPVWAIGTGKTATPDQAQEVHDQIRQWLNKNVSADVAKTTR ILYGGSVTASNCRELAQKADVDGFLVGGASLKPDFVQIINAT------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------YLPTEGKMVGDISNAWKGL ERAEKGFEEWLLSELQRLERLDHLAQKFKHKCDIHEEWAFGKEDMLQSRDFKRCRLNELK AIKKKHEAFESDLAAHQDRVEQIVAIAQELNALSYHDCPTVNARCQRICDQWDLLGTLTQ ERRIALEEAERILERIDQLHLDFAKRAAPFNNWMDGAKEDLVDMFIVHTTQEIQVLIDSH ETFKQTLGEADREFQGILSLQAEVQRLAQQHGLESALENPYTTLNAQDIQQKWSDVKSLI PARDATLRQEMIRQQNNERLRQQFAHKANAVGPWLERHNDLVMATGMQKGSLEEQLKKLN AYQVEANA---------------------------YTMETLRVRWEQLLTSIALNSNEVE NMILTRDSKGITEDQMVELRTSFNHFDKNHSRRLDPKEFKQCLVSLGY-MRDDQ------ LRIMAIVDANNTGFVSFDAFLDFMTRETTDTDTAEQIMQ--------------------- ----------------------------------------KKLSIDSVDVKDKRILIRVD FNVPMKDKSITNNQRIVAALPTVNLVLKNGAKSVVMMSHLGRPDGRPQEKYSLAPVAEEM RKLLGREVTFLSDCVGAEVEAACANPATGSVILLENLRYHIEEEGKGVDAGGNKVKASDA DVKKFRESLSKLGDIYVNDAFGTAHRAHSSMVGVDLPIKASGTLLSKELKYFEKALVSPS RPFLAILGGAKVKDKIQLIGNLLDKVNEMIIGGGMAYTFLKVLNNMEIGQSLYDEEGSKI VQTLMDKAKKNGVKIHLPVDFKTADAFSEDANSGEATVEGGIPAKWMGLDVGPKTTAKFI EVIKNAKLIVWNGPVGVFEFDKFAAGTKALMDAVVDVTKSGTVTIIGGGDTATCCAKWDT EDKVSHVSTGGGASLELLEGKTLPGVAALSDAMSGIPPSNWQPPNVTVDTSMGSFIVELY WNHAPNTCRNFAELARRGYYNGIKFHRIISNFMIQGGDPTGTGCGGASIYGKTFKDEIHP DLKHTGAGILSMANSGPDTNGSQFFITLAPTQWLDKKHAIFGRISAGMKVINRIGLADTD GNDHPRDEIKIV----------------RRKKPYKYWDKPPAGFEHISPMQYKAMQEGVP FAGSAVSRQARRLYVGNIPFGVTEEAMMTFFNEQMKSAGLAPSEGNPVIAVQINLDKNFA FLEFRSVDETTQAMAFDGINFQGQSLKIRRPRDYQPLPGMAEQPSVGVVSTVVPDSQFKI FIGGLPNYLNEDQVKELLMSFGPLKAFNLVKDSATGLSKGYAFCEYLDVACQGLNNMQLG DKKLIVQRASVGAKNAQQAAVQLQVPGLNLSSALTEVLCLMNMVVPEELEDEEEYEDILE DVREECSKYGLVKSIEIPRPIKGIEVPGCGKIFIEFQSPDQAQRAQQTLAGRKFSNRVVV TSYFDPDKYHRREFFVPLFDRVLVQRLLPEAKSKGGILIPEKSMGKVLIAEVKAVGEGTR TDNGDVRKMNVSVGEQVLLPEYGGTKVTIEEEEYHLFREGDILGKWQRLKSQIPDIKQSL DIVKYLKSKKDVIQTNFLLSDQLYAKATIPPTEKVCLWLGANVMLEYNLDDADALLTKNA ATSSLELVDNDLGFIRDQTTTLEVNMARVYNWDVKKRQTSKKMADEALSRAGLHFDELNK IRVLEPDSAQQTSELKEECKDFVEKISDFQKIVGTFIETVDNVAKEVEKEKMKAIGSRNL LKSIAKQREAQQQQLQALIAEKKMQLERLRLQHESLQKEEIEQNEFIEQFILQKRKRSRS RERKDSRRKRSRSRSRDELTPEERDARTVFCMQLPSSIRPRDIEAFFSSVGKVRDVRIIT DNKTRRSKGIAYVEFAECESVALALGLNGQPLKGKPITVQASQAEKNRTGDHKGPMRLYV GSLHFNITEEMLRGIFEPFGKIDHINLVMDSESGRSKGFGFVTFQTADDAKKALEQLNGF ELAGRPMKVGHVTERTADAAMLDSDEMDRAGIDLGATGRLALMAKLAEGTGFEIPPVAAN ALSLTQVTTAPPIATQCFMLSNMFNPVTSEPGWDQEIKDDVINECNKHGGVFHIYVDKTS PTGNVYVKCPSIAAAVASVQALHGRFFARKVITAAYVPLPNYHQLFPDAQVARSLLMSSA -ERDEDVSPTPPQPPKKRIRRGAVSAEVYTEEDAASYVKKVVPKDYKTMAALSKAIAKNV LFAHLDDNERSDIFDAMFPVHRHGGEVIIQQGDEGDNFYVIDIGEVDVYVNGECVTTIQD GGSFGELALIYGTPRAATVKARTDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLTKVSIL ENLDKWERLTVADALEPVQFEDNEQIVRQGEPGEDFFIITEGSAAVLQRRTDNEDQVEVG KLGPSDYFGEIALLLDRPRAATVIARGPLKCVKLDRQRFERVLGPCSEYLKRNISQYNSF VSLSVNSFRGLAKLNRLLYVADHALSYVQQTFNTNMYQQIHKKLQEAVSSNIPALDSQWV ETTAKKASVKLERLDIDLKNYRSNSIKESIRRGHDDLGDHYLECGDLSNALKCYSRARDY CTSAKHVVNMCLNVIKVSVYLQNWSHVLSYVNKAEATPEITEAKDGGQAVLTKLKCAAGL AELAVKKYKSAARNFLQASFDHCDFPELLSANNVAMYGGLCALASFDRQELQKNVISSSS FKLFLELEPQLRDIMHKFYESKYASCLKLLDDIKDNLLLDMYLAPHVNTLYTQIRSRALC QYFSPYLSADMRKMASAFNTTVTALEDELMQLILDGQINARIDSHNKILFAKDIDQRSST FERSFAMGKDYQRRTKALILRSAMLRNQIHVKCPPRDGAQGSEMSIAPGSAVSMLQKSEI IDKAEEVADQIVRHSKHILPHAARLCLIGTFLEDGIRMYFQWDEQRNYINEQWSCGWFLA VMFVLVNLVGQLGGCVMVLSRQKVEIACGILFGIIGLQTIAYSILWDFQFLLRNLALAGG VILLLAESKAEGKSLFAGLPSLGENNPKMYLQLSGRLLLVLMFITLLRFEFSPSLIVLNL IGSALIALVAVGYKTKLCALILVLWLTILNFTFNAWWSVPSYKPMRDFLKYDFFQTLSVI GGLLLVVALGPGGVSVDAQKKRWRQTVTMVPGDGIGSELMNCVRTVFTAAGVPVDFEEIF LSKNRVGLKGIIATPLETLNMKLRRSLDLFANVVLIKSLPGVQTRHKNLDFVIIREQTEG EYSALEHQSVKGVVESLKIITRANSLRIAKFAFDFATKHDRKKVTAVHKANIMKLGDGLF LECCSEVSKLYPTIEFESMIIDNCCMQLVSNPRQFDVMVMPNLYGNIVDNLAAGLVGGAG VVPGESYSHDVAIFEPGARHPYAQAVGRDIANPTAMLLGAASMLKHMHLEFHSDMIVNSI MKVIKAGKVRTPDMGGYSTTTDYTLAIVDELSEDFFKFFDRTSRVVERALTEEPDFYVDY TGRDGKDEL-QTEGLKSNRVFFDERWSKHRTVTCIDWSTQFPELLVASYNNNEESPHEPD GVTLVWNLKFKKDTPEYVFHCQSAVMSTCFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPV QRTPLSAAAHTHPVYCVNVVGTQNAHNLISVSTDGKMCSWSLDMLSQPQDSLELQHKQSK VAVTSFSFLSGDVNNFVVGSEEGAVYTACRHGSKAGISDMFEGHQGPVTGIDCNTVPGQV DFSQLFLTSSFDWTVKLWSIKEQRPLYSFEDNSDYVYDARWSPIHPALFASVDGNGRIDL WNLNNDTEVPTASTRSAA-NRCRWHQSGHSLAVGDDTGRIHIYDVAEHIANPKNDEWTKF VHTLQDIKNNATDRDDD----QLEEATKVIEQQVDAKIEELDRIGDEEYELLKKQRMQAL KKMANQKKEYMDAGHGKYFEVADEKEFFEECKKSKNVVCHFYRESTFRCKIVDKHLTSLA VKHLETKFIKIDAEKSQFLTKRLKITMMPTIALILDRKTVDFIKGFDDLGKVDDFSTELL EWRIAGAGVINYSGDLMVRPGSD--------------------------LEIQSLPSLKN DEVKVSVHFTGINFADVLMLSGKYQQKPPLPFVAGLEIAGLIKEVGKDVTKFKPGQRVLG LSGGFAEECIQLFEMPDSMDYKTGSALAVSYGTAWMALHKKAAIRESDTVLVTAGAGAFG SATLDLAKHSFSATTIGACGGKSSLLRSRGVDHVIDYNVEDIVEVVNDITKRGADVIIDA VGGDTFKKCLRSIGFEGRIVVIGFA---SGE-------------IPRIPAQVLLLNSCSV IGLYWGDYISVNAVIDLYREGSISPLVSTVFSLDEVNEAFHHIHNRKSTGKVVL----MS RKQTPSDFLKLIIGRPVVVKLNSGVDYRGVLACLDGYMNIALEQTEEYVNGQLKNKYGDA FIRGNNVLYISTQKRKVMASTTAVALLRKQLLDIGKCKHTGYSAGLIDDNDLFKWEVCV- ------------------------------------------------------------ ------------------------------------------------------------ ---TVRPTNELVQHDLTDFGAYVADCLPKFVQKAQVTVGDELEILVSPEGVIPVITFLKD HHQGQFLSLADIAGVDVPARKYRFEVVYNLLSLRYNKRIRVRTYTDEMTPLDSTTSLFAA SDWYEREIWDMYGVFFANHPDLRRILTDYGFEGHPFRKDFPLSGYVELRYDDELKRIVVE PIELAQEFRKFEYSSPWEMFPSHRASLNPFSQVDYRSKTWTCNICFNRNPFPPQYAAITE QHQPAEIIPQFSTIEYTLMRATCHPPVYLIVLDTCMDEEDLQAVKESLQMSLSLLPPNAL IGLITYGKMIQVHELGCEGCSKSYVFRGTKDLNAKQIQEMLGIGKGV-QLPSNRFLQPVH KCDMALTDLLGELQGDPWPVAQGKRPLRSTGVALSIAVGLLECTYPNTGARIMMFVGGPC TQGPGMVVGDELKHPIRSHHDIEKDNCKYMKKAMKFYEGLANRAANNGHLVDLYSCALDQ TGLHEMKYSCNLTGGHMVLGDSFNTSLFKQTFQRVFKRDSKGEFQMGFGATLEVKTSREL KVCGAIGPCISLNNNQCVADTEIGVGNTASWKICGIYPNTTLGVFFEVVNQHNAPIPQSG RGYIQFVTQYQHSSGQRRVRVTTLSRSWVDASVNIQHVAAGFDQEAAAVLMARMAMFRAE SDDVQDVLRWLDRMLIRLCQKFGDYHKDDQNSFRFSEQFSLYPQFMFHLRRSQFLQVFNN SPDETSYYRHSLNKEDLVQSLIMIQPILYSYSFNGVPEPVLLDSDSIKPDRILLMDTFFQ IVIYHGEIMSQWRKEGYHNLPEYDNFKQLLQAPVDDAQDILETRFPMPRYIDTEAGGSQA RFLLSKVNPSQTHNNMYTEGGAPVLTDDVSLQVFMDHLKKLAVSSSS-----NEEQLKIV GELEIEMMADMYNRMTTSCHKKCVPPKYKDSELTKGECVCIDRCVAKYLDIHDRIGKKLT SISAQDEQALKKLQ-TQSAAIIHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYR KKVVLDGEEVQIDILDDYAAIRDNYFRSGEGFLCVFSITEQESFQATAEFREQILRVKND DNIPFLLVGNKSDLEDRRQVTVEEAQQRAGQWSVPYVETSAKTRANVDK----------- ---------------KLYTGLREVVTDHLISKVREDVLTALHNNFLQTLNSSWNDHQTSM VMIRDILMYMDRVYVLQNNVDNVYNLGLIIFRDQVVRYPVIRDHLQTTLLEMVAKERRGE VVDRGAVKNACQMLMVLGIDSRSVYEEDFERPFLKQSADFYRLESQKFLAENSASVYINK VECRINEEAERATHYLDKTTEEPIVQVLEEELISKHMKTIVEMENSGVVHMLKNNKTDDL GCMYKLFIRVPDGLRTMCACISAYLREQGKALVAEE-EGKNAITYIQSLLDLKDRFDHFL HLSFNDDMQFKQMISSDFEHFVNLNTKSPEYLSLFIDDKLKKGVKGMTEQEIESVLDKSM VLFRFLQEKDVFERYYKQHLAKRLLLNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFKD MTVSNSTMEEFKEHVKTAKNLCGVDLFVRVLTTGFWPTQSATPKCTIPLAPRTAFDDFRR FYLVKHNGRQLTLQPQLGSADLNATFFGPRKDDS-------------------ILMLFNS RDKYTYEELKNETDIPERDLMRAIQSLALGKMTQRILCKEPK--------VFGVNDQFTS RLFRVKIQTVAAKGESEPERKETRNKVDEDRKHEIEAAIVRIMKARKKMQHNVLVAEVTE QLKARFLPSPVVIKKRIEGLIERDYLARTPEDRKVYTYVADRINVFPSRMALTIMKARLK GAEKGHSLLKKKADALTLRFRQILKKIIETKQLMGEVMKEASFSLAEAKFATGDFNHMVL QNVNKAQIKVRTKRDNVAGVVLPVFEHYADGTDNYELAGLSKGGQAIDRLKKNYAKAVVL LVQLASLQTSFITLDEVIKITNRRVNAIEYVIIPKIERTLSYITAELDEREREEFYRLKK IQEKKKIIR---------------LKIVVTGAAGQIAYSLLYSIAKGDVFGKEQKMELVL LDILPMMEALNGVVMELQDCALPLLTAVHPSADANSAFQNADVGILVGAFPRKEGMERKD LLKANAKIFKSMGEAIEANAKKTIKVIVVGNPANTNAMLCSHFAPSVQKRNFSALTRLDH NRAQSQVAMRQAVKKVIIWGNHSSTQYPDLSHSVVATEALKDDNWVKGEFLKTVQTRGAA IIKARKLSSALSAAKAICDHMRNWWCGTPEGNWVSMAVPSDGYGIPEGVIYSYPVTINRD YKIVQGLEISDFSREKMDKTYKELAEEKETAM---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------AKEYIDPETSKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEAL GHMFMYFLRGSLPWQGLKADNLKERYQKXGDTKRATPIEVLCEGFPEELARYLKYVRSLD FFETPDYDYLRKLFQDLMEKKGWDSDWEFDWTGRQMRHGGSVQVVSSTNGELAP-TGRST VPFTTPADVDVVDDTKCCMTTIRPFTCDDMFRFNCVNLDPLTETYGLPFYLQYLAHWPEY FKVAESPSGRIMGYIMGKSEGRPENWHGHVTAVTVAPDYRRLGLAGSLMTLLEVISDKKR CFFVDLFVRVSNKIAVNMYHKLGYTEYRRVLEYYSGEVDEDAYDMRKALSRDVEKKSMIP LRHPVRPSDLERQLDCALDLMRRLPPQQIEKNLSDLIDLVPSLVEDLLSSVDQPLKIARD KTNGRDYLLCDYNRDGDSYRSPWSNVYDPPLDDGALPSDRLRSLEIEANSAFEQYTEMYF EGAVSSVYLWDLDHGFAGVILVKKAGDGSQKTKGCWDSIHVIEVQNR--GRGAHYKLTST CMLWMQTNKSGSGTMSLGGSLTRQAEMDGIVSEASPHIVNIGKMVEDMENKIRMTLGEIY FGKTKDIVNDLRSINSLHQIALQRDLKDALVRRAEFEDAIDEIDEPLDEVEQTEQVDVLP AAEEVAPENRITTPYMTKYERARVLGTRALQIAMCAPVMVELEGETDPLQIAMKELKAGK IPIRIRRYLPDGSYEDWAIDELIIT-VGETIKQTVATPAGESAFSLGKGAIAGASLVGLG ALCYYGMGMSSELGAIDRATLWPPIVKERIRDTYMYFAGSIGITAVKRSPKILEFMMKNS LIGIGATFALMIGSGMVCRSLPYEEGAKQIAWLVHSGIMGAVVAPVCLLGGPLLVRAAWY TAGVVGGLSTVAICAPSEKFLNMGGPLAIGLGVVFVSSLGSMFLPPTTALGAGLYSMSIY GGLILFSMFLLYDTQKIIKSAEMHPVYAMQKYDPINRSIGIYLDTLNIFMRIATILAGGG NRRR-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -QLAYWDTRKGSQPVEMSPIEHSHRDPLYKAIWIQSKTGTECFSASTDGQVLWWDIRKLG EPTEKLILDPTKKQDPTKAQGSMSLEYEPTIPTKFMVGTEQGTILSCNRKAKTPAEKIVN VWGGHHGPVYALQRNPFFPKNFLSVGDWTARIWSEDIRDSSIMWTKYHMSYLSDGCWSPI RPAVFFTTKMDGTLDIWDFLFKQNDPTLSIQVCDEPLYSLRVQEQGRLIATGSHTGTTTL LEMSDSLCTLQRNEKNLITAMLERETRREKILDARHRENKLKERAKSGYDELLKFVSVIS NPLASRKLTKKLYKLTKKALRKGVKDVQKQIRKGEKGIVVMAGDTNPIDVISHMPVVCEE ASISYCFTPSREALGAASGSKRPTCMLLIKPNAEYQDLFDEVNEEMKSLPMPVMPVENLE EQGLEKNPNLQLATWKWLLTTDKFRNDKQIKNDLLEAMKTDNMAPFYTEVCKDLSWKLDE KLLASMQKANEEELKKIDEQQEDAEKNMGETEVRDFMLKKGEYLCKIGDKEGALSQFRKT GEKTTTLGYRLDMVFHQIRMGLFYMDKDLINRNLEKAQSLIDEGGDWDRRNRLKVYRGVY CMANRDFKTAANLFLDTVATFTSYELMEYTDFVTYTVLCSMISLDRNDLRERVVKGSEIL EVLHSLPEIRTYLFSLYNCQYAEFFKSLSHIESLLKHDRVLHLHYRYYIREMRILAYTQL LESYSSLTLQYMANAFGVSIKFIDQELSRFIAAGRLHCKIDKVGGIVETNRPDSKNYQYQ ATIKQGDILLNRIQKLSRVINISRGLRGSAEPIKGIAYKDLTIGVPKETFKNELRVALAP SSAATLKKGFNVSVEENAGTGAKFTNDDYASVGCKVPRDEVFKSDIVTKVRAPETNEIPL LRENATLISFLYPGQNKPLIDLLAQKKLTVFAMDAIPRISRAQVFDALSSMANIAGYKAV VEAANNFGRFFTGQITAAGKVPPAKVLVIGGGVAGLSAVGTAKNLGAIVRAFDTRAAVKE QVESFGAEFLEVNLKESGEGTGGYAKEMSPEFIAAEMALFAKQCKEIDILISTALIPGKP APKLISKEMVESMKPGSVIVDLASEAGGNIVTTKPGELYKYKDITHIGYTDFPSRLPTQS STLYGNNISKFLLSIGYNVNLEDEVVRGSIILQNGTMMWPPPPPPPPNYFAMYFKDSMYY TAGMGTVLGLGMVSPNAAFTTMVSIFGLSGIVGYHTVWGVTPALHSPLMSETNAISGITA VGGMLLMGGGYFPTDTSQSLAAIAAFISAINIGGGFVVTQRMLDMFKRPDDPPEYNYLYG IPGLTFLGGYGYAAMNNFPDVHQMAYLAASLCCVGALSGLSSQKTSRLGNALGIMGVTTG IGATLGILKPDPEVFAQMASCMGLGGTIGAVMAKRMEVTDLPQMVALFHSLVGLAAVLTC FSNYFVELPHFATDPAANVIKTSLFLGTFIGGVTFTGSLIAFGKLQGMLKSDPLLLPGRH LMNGGMLAANIGALGVYMMDHDTMNLSMLGVTAGLSSVMGLTLTSAIGGADMPVVITVLN SYSGWALCAEGFMMNNNLMTIVGALIGSSGAILSYIMCKAMNRSLPNVILGGLKTKSFAG GKPMEITGTHTETDSASVVDMIVNSKNIIIVPGYGLCVAKAQYPIAEIVDILGKHGKNVR FGIHPVAGRMPGQLNVLLAEAGVPYDVVQEMDELNDDFPDTDLVLVIGANDTVNSAAEED PNSIIAGMPVLRVWLAKQTIVMKRSLGVGYAAVDNPIFFKEQTSMLLGDAKKTCDALLAG VK----PQVPGCPPGLEYLTQIDQLLVHQQVELLEAFVGWECKNKYQIKNAMGQQVYFAA EESDAFQRQCCGPQRGFTMHITDNMNQEVIRIERPFKCCAGVNCCAGCAMEITIESPPGT VVGFVQQECLEPRYSVMNAVLEIVGPVCVCQGPCC-GDVEFAVNSTQVGKISKQWTGLVK EYFTDADNFGVQFPMDLDVKMKAVMLGAVFL-----------GSEEELQQFIQLEQQKAL FQTQIHRLADVCWDKCIDKPSNKLDSRTETCLTNCVERFIDTSMSITNRFQQMISQ--MN RSDGLVQRRHVSQSDYDLDSKETRFTLMEEVLLLGLKDREGYTSFWNDCISSGLRGCILI ELAIRGRIELEKTGMRRTRLQNRKIVCKSDVPTGDVLLDEALKHIKETEPAETVQTWIEY LSGETWNPLKLRYQLRNVRERLAKNLVEKGVCTTEKQNFLLFDMTTHPLNDNVIKQKLVK KVQEAVLNRWVNNAHRMEKRMLALIYLAQSSDVLENAFAPLSDDDYELAMKRVHDLLNLD PEQESMKDGANELMWAVIFAFNKSKK---ITKENCEVCVGVMEKFEKTLTKIRTEFVKFC EKLKSKEERFCYYIGGTKDSATSILNVMTRPVSLTMPPTKTCEKLYEKDSQICDLKYEKK IDLVNANFRKMKVKELKKILSDWDADCRGCAEKSDYIKRIMELMPENDPEAY---ILSGF KLNWMNLRDADTGKILWQGNDDLSSPDSEHEA---------------------------- ----------------------------------------QMMPPNVLSGNVVIETYFYD GDLLVSTSKVRIFYV-----------------EEYQGEKPLYVYYCLCGQMSCILDCPLE KLPMRRRDDARVIDRSKHAHKLTFDIGDTVHLRRPEGIERQFRKKCKKCGLWIFYQHKAT VTFIVDGALKLSAEAKASLYGQVAAPKKVTLTKHTKNMGKCSSVTVSTVDEEEEEIEAKE IADSY-------------------------------------------------FQQRTR NYADMAFTFASPSEVAVKQVDVPSMSGSFGILPEHVPSLAVLKPGVVTVYEEDGSQNKYF VSSGSVTINDDSSVQVLAEEAVPVDQLDAQMIRDGMTRCPDD------------------ -------CKYLVTELQDRLRETGKYKQTIETGYNLDNKKKIDYRTSELRLAEALVDPHIC DRILQYNVHKEKEGSLRFAKGQSETMRTLHGLVNKGVKVDLGIPHDLWDSPSAEVTEMQK HCYTMVGDYEDEIEEWYFHHQEDLADWLCAKRILK----IFVPTDVTNTEQVLAALSAKE QFGRLDIAVNCAGIGIAHRTYNFNKETPHSLDDFMKVLTVNTVGTFNVIRLAAGLMGKNE PNVDGQRGVIVNTASVAAYDGQIGQVAYSASKGAIVGMTLPIARDFAKQGIRVCTIAPGL FDTPLLAGLPEKVRNFLSSTIPFPSRLGLPDEYGHLVQMIVENPLLNGEVIRLDGALR-- -------------------NYPIVDHTYDAVVVGAGGAGLRAAFGLAKEGFKMACVTKLF PTRSHTVAAQGGINAALGNMEEDDWKYHMYDTVKGSDWLGDQDAIHYMTEEAPQAVIELE NYGMPFSRLENGKIYQRAFGGQSINYGKGGQAHRCCAVADRTGHSMLHTLYGRSLKYDNM YFIEYQALDLLMDNGKCVGLIALCLEDGSIHRFRCKNTILATGGYGRTYFSCTSAHTCTG DGTAMVTRAGLANEDMEFVQFHPTGIYGAGCLITEGSRGEGGYLINSEGERYMERYAPNA KDLASRDVVSRASTIEIREGRGVGAENDHVYLKLSHIPADILHSRLPGIMETAHIFAGVD ATREPIPVLPTVHYNMGGVPTNYKGQVIQFKGDDVVVPGLYAAGEVACASVHGANRLGAN SLLDLVIFGRACANTIIEQDKPGDKLPELKQNAGEESVANLDKIRYMDGKTPTADLRLDM QKAMQEHAAVFRDGPSLKEGCQKMDNIYQNMDLKVTDRGMIWNSDLVETLELQNLMLNAV QTIVSAENRKESRGAHSREDFKDRLDEFDYSKPLEGQKKKPIEEHWRKHTMIHMEEKSGK CKISYRPVIDKTLDENVIKSVPPKVRTY-----------NTKTVVQGLETLKNEHNQILN SLLTSMKTIKKGDTNLVEEKTGILKKSVEMIELGLGEAQVMTSLASHLQHVEAEKQKLRA QVRRLCQENAWLRDELANTQQRLQQSEQGVATLEEEKKHLEFMNEMKKYDTDDGLGFPED DDDSTTSAMSQAATGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHD HPDVATMLNILALVYRDQGKYKEAANLLNDALGIREKTLGHDHP---------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------KLNESDAPFKKMENINNFLKAIEFYGVPKTGLFQTVDL YEGRNMTQVLNSILQLGSEAQRHGFNGMTIGPKPTEKNFREFSDAQLKAGQLQAGTNKCA SQGMGATRHISDIKVDDMSKEGQGVIGLQAGNKGASQ----------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -SYSFGAHSISCHAWNKDRTSLALLNNAEVNIYSQKWEIVHTLKEHTQRVTSIDWGADQN RIVTCGVDRNAYVWPTLVILRINRAATCVRWSPKEDKFAVASGARLIAICYFEKEYDWWV SKHIKKPLRSTVTSIDWHPNNVLFAAGSSDFKARVFSGYIKEVEDKPSATPWGKKMTLGS LMCEFSNGGGWVHDVSFSASGNKLAWVGHDSRISVVDSSVKSKFLPFTTCMWVTENSLVV AGHDCCPMLFVHGDDKLTFMNKLDVSSLSAMQRFRSLDANKGAAKTIHLNTITQISMYAG DKAHCSKFTTSAVDGQICIWDFK---DGYVGFANLPNQVYRKSVKRGFEFNLMVVGESGL GKSTLINSLFLTDLYNTEHPGPSLRIKKTVNVETTKVLLKENGVCLSLTIVDTPGFGDAV DNSNCWQPIIDNINSKYEEYLNAESRVNRKLMPDPRIHCCLYFIAPSGHGLKPLDVEFMK RLHDKVNIVPLIAKSDTMTPDECREFKKTILNEIAQHKIKIYEFDDEEENKIQKALKTRV PFAVIGSNTVTDLGGRKIRGRVYPWGVVEVENLEHNDFIALRNMVIRTHMQDLKDVTNNV HYENFRYNKLAGPSKSPILQMEEEKKEHDAKLKKMEAEMEQVFEMKVKEKQQKLKDSEAD LQRRAEQMKKSLEQQEKELEEKRQQFEKEKQMWDE---MSRRYDSRTTIFSPEGRLYQVE YAMEAIGHAGTCLGILAKDGVVLAAERRNTNKLLDEVSYSEKIYKLHEDMACSVAGITSD ANFLINELRYSAQRYLFYYGEPQPCEQLVSSICDYKQLYTQIGGKRPFGVSLLYMGWDKH HGYQLYQSDPSGNYGGWKATCIGNNSAAAISMLKQDYKE-TIELKDALLLSLKVLNKTLD INKLSSEKMELATLTRENGKTVIKVLPTSEVDELLKKHEAAEAKSDAEKKEELNEAWMRL KSLAQQRQEKLFGAREIQHFNRDCDETIAWINEKDVTLSSDDYGRDLQSVQALQRKHEVI ERDLAALGEKVESLDTEAERLEDLHPECGDQIHNKRSEIDSNWDSLKRKAESRKGRLDAA YYLHRFLADFRELITWINDMKAVISADDLAKDVTGAEALLERHHEHKGEIDAREDSFRAT AEAGQALLESDHYAVDDVKEKLVMLANDKTSLLELWEERRILYEQCMDLQLFYRDTEQAD TWMGKQEAFLTNEDLGDSLDSVEALIKKHEDFEKSLTAQEEKVKALDDFATKLIESEHYA ADDVAQRRDALLQRRTVLIERSTTRKHLLEDSYRLQMFERDCDETKGWINEKLKAATDEN YTDPTNLQGKVQKHQNFEAEMTANASRIESVNTTGTELIDNQHYATDTIQDRLDEIDSLW KQLLNQSEKKGKKLNEASGQQQYNRNVEDIEIWLSEVEGQLMSEDYGKDLSNVQNLQKKH ALLETDIGSHQDRIDGIAEQAKQFSEEGHFDVENITAKQAVVLERYQTLQAPMTKRRDRL QDAVLLQQFYRDVEDEEDWIKEKEPVATSTNRGRDLIGVQNLIKKHSALQAELNGHDNRI EEVYDEGEKMILNGHYASDDIRRQIDDLKEKWNGLNDKANQRTQDLDDSMQAQQYFADAN EAESWMKEKEPIVGSTDYGKDEDSSEALLKKHEALMADIDAYRASIDALRNEAENCRQQE APLLDDQGKEYVFALYDYQEKSPREVSMKKGDVLVLLNSANKDWWKVEVNDRQGFVPAAY VRRTEGALSSSQSNLADEYTVSTRQRQIENQYENLLDLGQQRTNKLKESNRAFQLVREAS ELTQWISEKETIAVTEVVPTDLEHVEHQQRKFEDFQKDLKTNEARLMEMNTIAETLEALG QVESADKMRVHVQNLNERWTALEQVTQEKADNLMSSHEVQRYLRDVDETLDWIEEKDHAL NTDNVGNDLSTVQRLQRKHEGVERDLAALGDKVRVLDETANRLMQTHPDQAEQIYHHQTD LNEKWNSLTGKADARKSKLLDSYDLQRFLSDFRDLMSWINSMMSVVSSDELAKDVTGAEA LLERHQEHRTEIDARAGTFQAFEMFGNQLLQNNHYASDEVKDKLDELANAREDLEKAWVA RRAKLDQCLEMQLFLRDCEQAELWMATRETSLSDNTDG-ENVDSMIKKHEDFDRAINVQE EKISALQNFADQLTAADHYDGDKIDAKKAEVLDRWSNLKEQLIENRSKLNEAQTMQSFSR DADEMEAWLTERLQMATEESYRDPTNVQSKHQKHQAFEAELAANSDRLKQVLSAGEKLIE RQQCLGSEDAVNSRIVNLTEQWEYLITKSREKSEKLKEANRQAVYNAAVKDMEFWLGEAE HMLESEDYGKDLSSVQHLLKKHQIIEAEVEAHEDRLNDLNNHADLFIESGVGDADAILER KKTINERYETVKERCEHRRVRLNEANTLHQFFRDVDDEEAWIREKKLLVGSDDFGKDLTG VQNLRKKHKRLDAEITSHEPAITHVQEMGRQLMEETTLGSEEIQTRIDQLSANWDELKEM TTTRGQKLDESLAYQEFCSGIEEEESWINEKQHLLSGEDYGDTLAAVQGLIKKHDVFATD FQVHQDRCTEIYKEGDKLIEEGNHNAESISARCSALREKLEDLMAAADRRKAKLIDNSAF LQFIWKTDVVESWIADKETQVRSEDYGRDLSSVQTLLTKQETFDAGLQAFEKEGIQTITA LKDQLVAAEHVQTVAIEKRYDDVIRRWQKLLADSESRKQRLLRLQDQYRQVEDLYLTFAK RASAFNSWFENAEEDLTDPVRCNSIEEIRALHEAHEQFKASLGTAQADFDRLAELDKQIK SFNVGPNPYTWFTMEALDDTWKNLQKIIKERDQELERERERQEENDRLRIQFADKANHFH SWLTDTRTAMMEATGSLEEQLEQTKRKSAEVRAQKGQLKHIEDLGASLEERLILDNRYTE HSTVGLAQQWDQLDQLGMRMQHNLEQQIQARNQSGVSEDSLKEFSMMFKHFDKDKSGRLD HHEFKSCLRALGYDLPMVEEGQTDPEFQAILDSTDPNRDGYISLQEYMAFMISRETENVQ TSQEIIEAFRALTSDEKPYITTNELYANLSKEQADYCLRHMKPYTDKSGHELMDAWDYTD FTNSLFAN----YQCDSNEDNSCPADRWFDQSMNALVDCGGFEAHVPGTFCVKIYQESPG WNGWVKITRRCGSRTDTGVAWGCRYWYEDNGVFKETCYCD----------IDANDRGNPQ LVTEYVNDIYQYMRHLEDKEINGRMRAILVDWLVQVHTRFNLLQETLYLAVAILDRFLQV PVPKSKLQLIGVTAMLLASKYEEMYAPEVGDFEYITDNAYTKSEIRKAEVFMLKALDFNL GKPLALHFLRRNSKAGDVDANKHMLAKYLIELTIIDYEMVHHKPSEIAAAALNLSMKIYD WGDTLTHYSTYSDDFLKPIVSKIANLAVKKLSAVYDKYYSSKFNKVS------------- -----------NNPSPGPEDGLERVFIWDLDETIIIFHSLLTGSYATRYGKDPPSSVSLG LRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSSYNFATDGFHAAATNNLCL ATGVRGGVDWMRKLAFRYRRIKEIYNSYRNNVGGLLGQPKREQWLQLRSEIEAMTDSWLT LALKSLQIINSR------------------------------------------------ ----------------------------------------------------MATLSVGG ERTTGQSIRTQNVMAASSIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKMLEVEH AAAKILVELAQLQDEEVGDGTTSVVIIAAELLKNADELVTNKIHPTSIITGYRLACKEAC KYIQEHLTLGVDELGKDSIINAAKTSMASKVIGSDADFFSNMVVDAANAIKVSDGKGGHR YPIKAINVLKAHGQSSRESQMINGYALNCTVASQLMVKKITNAKIACLDFNLQKAKMKMG VQVLVSDPQKLDAIRQRESDITKERIEKILATGANVILTTGGIDDLCLKYFVEVGAMAVR RCKKADLKRIAKATGGQLVMTMANLEGDESFDATNLGQADEVMQERICDDELILIKGTKA RTAASIILRGANDFMVDEMERSIHDALCVVKRVLESKSLVPGGGAVEAALSIYLENYATS LSSREQLAIAEFARSLLVIPKQLAVNAAQDSTDLVAKLRAYHNSSQTKSEHADLKWVGLD LYEGVVRDNKKAGVFEPAISKIKSLKFATEAAITILRIDDMIKLAPENKGGPSYQQAVNS GMLDDSTARLLASKNVLNPYIVEGKELTVEYSIYNVGGGAAFNVKLNDESFPEQDFDRVI GMLNVKWERIAPGSNVSHVVILKPTNYGVYNFTSGELHYQSTEDETIFGHTSAPGHREVI PSKEYERRFSPHMLDWGAFAVMTLPSLGIPFLLWWGSKSKYEQLKPKKN--------TVR YRATLDLIEGLKYFVEAMVNENVSLVVSRQLLADFSAHLPVLSDDLAKQISHYTLEKIQP RVISFEEQVASIRQHLGNIYEREQCWKEAANVLVGIPLETGQKQYSNDYKLETYLKIARL FLEDSDPVQAEAYINRASLLQADSQNEELLIHYKVCYARVLDYRRKFIEAAQRYSELSYK NIIAEEERMLALKNALICTILASAGQQRSRMLATLFKDERCQQLPAFSILEKMYLDRIIR SSDLIEFEALLQSHQKATTSDGSTILDRAVIEHNLLSASKLYNNISFEELGALLEIPPAK AEKIASQMISESRMNGCIDQIDSTVHFETREPLPNWDKQIQSLCVQVNNIIEKIATVAPD WISQHFEAHMA--------------------------MNFSANGETLISSSDDDSIVIYD CQNGTPKRTLNSKKYGVDLIQYTHATNAAIHSSTKVDDTIRYLSLHDNKYIRYFPGHTKK VVTLCMSPVDDTFLSGSLDRTIRLWDLRSHNCQGLMHLTGRPVAAFDPEGLIFAAGINSE HVKLYDLRSFDKGPFATFKLTQDRECDWTGLKFSPDGKMILISTNGQV-HLIDAFQGASL QTFMGITNNKGLAMEASFSPDSQFVFSGSTDGRVYCWNTETGARVAILNAEHGGAVQCVQ FNPKYMMLASACSNMAFWLPQLDEKNILVEKKGEKQNVGYIQLNRPKALNALNDELFCEL LDALKSFDHDDQVGAIVLTGNEKAFAAGADIKQMCGGKFNEIYRSNFLAHWAGVADTRKP IIAAVNGFALGGGCELAMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRMTQAVGKSKAM EIVLTGDRVKADFAEKAGLVSKIFPVDQLVDEAVKTAEKIANHSKITVAMAKEAVNKSYE MTLKEGLDFERRLFQATFATDDCKEGMTAFIEKRPANFTD >Typosyllis_sp XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----RQFQTSVSRQDIDQAAKYIGAGAATV GVAGSGAGIGSVFGSLVIAYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLLLYAFX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMDQVM QFVDPAKQFAKDSLRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNII V-ANPVSKKRKFVADGVFKAELNEFFTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVL GEKGRRIRELTSVVQKRFNFQEGTVELYAEKVATRGLCAIAQAESLRYKLIGGLAVRRAC YGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGEPINDYVDTAVRHVLLRQ GVLGIKVKIMLPWDPTGKIGPKRPLPDHVSIVEPKDEVVPQTPISEQKGGKXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-GKPRGIRTARKQRNHRREQRWHDKD YKKSHLGTRWKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVP RDGCLNYIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKEKKERPRSXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPGV PLVSGKTYMTPRRPFEKERLDQELKFIGEYGLRNKREVWRVKYTLAKIRKAARELLTLEE KDPKRLFEGNALLRRLVRIGVLDEGKMKLDYVLGLRVEDFLERRLQTQVFKLGLAKPIHH ARVLIRQRHIRVRKQVVNIPSYVVRLDSQKHIDFSLRSPYGGGRAGRVKRKNMKKGQSSG GGMGNMFTNLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVGEAREELCRMLSEDELRD AVLLVFANKQDLPNAMNAAEITDKLALHTLRQRNWYIQATCATSGDGLYEGLDWLSNQLK NQKMPLVKDLLHPSVDEERRQCKLKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCV GCSTVLCQPTGGKARLTEGCSFRKKQHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXMTEQMTLRGTLTGHGGWVTQIATTPQYPDMILSASRDK SLIMWKLTRDTNYGIPQKSLRGHSHFVSDVVMSSDGQFALSGSWDGSLRLWDLSTGCSTR SFIGHTKDVLSVAFSADNRQIVSGARDKTIKLWNTLGVCKYTIEDGHSEWVSCVRFSPNT SNPIIVSCGWDRLVKVWNLTNCKLKTNHIGHSGYLNCVTVSPDGSLCASGGKDGQAMLWD LNEGKHLYTXDGGDVLNALCFSPNRYWLCAATGPSIKIWDLEGKIVVDELRQEVISTGGG PPDCTCLAWSADGQTLFAGYTDNVIRVWQVSMAARXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFSAGAKIVKPTGEKPDDFESSISQ ALLELEMNSDLKAQLRELFISAAKEIDVQGKKAIVIFVPVPQLKAYQKIQVRLVRELEKK FSGKHVVFIAQRRILPKPTRKTRRKNKQKRPRSRTLTAVHDNILDDLCYPAEIVGKRIRV KLDGSRLIKIHLDKTQQTTVEHKMDTFSAVYKKLTGKDVMFEFPEYVL------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------QVTGKCGSVVVRLIPAPRGAGIVSAPVPKKLLQMAGIDDC YTSARGQTATLGNFAKATYAAIANTYSYLTPDLWKETTFTKSPYQEFTDYLAKMSGGLDA LALKEEDVAKLIASSCHLGSTNVDFQMEQYVFKRKPDGIYIFNSRKTWEKLLLAARAIAA IENPADVCVISARPYGQRAVLKFASQTGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDP RTDHQPVTEASYVNIPVIAFCNTDSPLRFVDIAIPCNNKGIHSVGLMWWMLSREVLRLRG TISREVPWEVMPDLFFYRDPEEAEKE---------------------------------- -------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNPEKLKARIGGKGSARRKKKVVHRTATTD DKKLQSSLKKLAVNNIPGIEEVNMIKEDGQVIHFNNPKVQASLAANTFAITGHAETKQIT EMLPGILNQLGAESLANLKKLATPTGDIDEDDDDVPDLVENFDEASKGEMTRYSLDSDNP TKSAKARGSHLRVHFKNTRETAHTIKHMHLRRAVGFLKNVTAKQECVPFRRFNGGVGRCA QAKNHKATQGRWPQKSAEFLLQLPKNAESNAEYKGLDTDHLVIEHIQVNRAPKMRRRTYR AHGRINPYMSSPCHIEVILAEREQAIAKPKKKKVSQKKLKRQKMMMREXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXMGISRDKWHKRRKTGGRMAPLRKKRKFELGRPPANTKLGP KRIHTVRTRGGNKKYRALRLDTGNFSWGSEAQTRKTRIIDVVYNASNNELVRTKTLVKNA IVQVDATPFRQWYEAHYATPLGRKKGVKLTEADDAILNKRSRSTKKKYALRKKTAKVENA LEEQFSSGRVLAAIASRPGHIGRCDGYVLEGKELEFYMRKIKAKKGKXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXGSGSESDSSDGVPDLE-MAQAAGLPEELVSKAKQSRSEKKA RKAMSKLGLKQVPGVSRVTIRKSKNILFVINRPDVYKSPASDTYIVFGEAKIEDLSQQSA VRAASQFKTEGEVDETGVEAKDIELVMSQANVSRTKAVKALKNNSNDIVNAIMXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMRELRISKL CLNICVGESGDRLTRATKVLEQLTGQQPVTSKARYTVRSFGIKRNEKIACSCTVRGAKAE EILERGLKVKEYELRRNNFCLTGNFGFGVQEHIDLGIKYDPGIGIYGMDFYVVLNRPGFG VSKKRRRVGKIGPAHRIHKEEAMKWFQQKYDGVILPGKXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRRPARCYRYCKNKPYPKSRFCRGVPDS KIRIFDLGRKKARVDEFPLCVHLVSDELEQLSSEALEAARICCNKYLVKHCGKDAFHIRM RPHPFHIVRINKMLSCAGADRLQTGMRGAFGKPQGTVARVRIGQPLISVRARDQNKAEVI EALRRAKFKFPGRQKIYVSRKWGFTKWNRGQYEEMRQNGILIPDGVSVQYKPNKGPLKAW MNRQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-GGLQYMQELYRKKQSDVMR FLFRVRCWQYRQLTSVHRTSRPTRPDRARRLGYRAKQGIVIYRVRVRRGGRKRPVPKGAT YGKPTNQGVNQLKFGRSHQNVAEERAGRHCRALRVLNSYWIGQDSTYKFFEIIMVDPFHK AIRHDAKMNWICRPVMKHREMRGLTSAGKKSRGLGKGHKFTQTIGGSRNACWKRNTRLSL RRKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXX-----FKLVLVGDGGVGKTTFVKRHLTGEFEKKCVATLGVEVHPLAFHTNRGIIRF NVWDTAGQEKFGGLRDGYYIQGQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCG NKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLVGDANLEFVAMPA LAPPEVQMDPDLKQRYEDELKAAQNTALPDDDDDLXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSIGV PIKVLHEAEGHIVTCEAKTGEVYRGKLVEAEDNMNCQMSDITVTHRDGRVAQLENVYIRG SKIRFLILPDMLKNAPMFKKVGAGRGKSAILRAAARGRGRGAGG-----XXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXMARGPKKHLKRLNAPKHWMLDKLGGVFAPRPSTGPHKLRECLPLMVFLRN RLKYALTYTECKKILNQRLVKVDGRVRTDNTYPAGFMDVLSIEKTGENFRFIYDVKGRFT VHRIQPEEAKYKLCKVKRVSTGPKGVPYITTHDARIIRYPDPNVKSNDTVQVXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXMSARYDRAITVXSPDGHPLQVEYAQEAVKKGPTAVGVR GNGVVILGVEKKAXAKLQEDRTVRKIALLDDHVAMAFAGLTADARILINRARVECQSHKL TVEDPVTLEYITRYIAQLKQKYTQSNGRRPFGLSTLLIGFDGTPKLYQTDPSGTYHEWKA NAIGRSAKTVREFLEKHYTEEVATEKESIKLALKALLEVVQSGSKNMEIAIMRHKQPLQM LGTEEI---------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-RKPYSPFK-DNKVDYALAR VDDLVNWARKSSLWPLTFGLACCAAEMMHFAAPRYDMDRFGVVFRASPRQADCIIVAGTV TNKMAPALRKVYDQMPHPRWVISMGSCANGGGYYHYSYSVLRGCDRVIPVDIYVPGCPPS AEALLYGILQLQKKIKRMETAQRYYRR--------VGHKGKFGHEFLEFEFRPDGKLRYA NNSNYKNDTMIRKEAYVHKSVMEELKRIIEDAEIVQEDDGLWPPPDRVGRQELEIVIGDE HISFTTSKIGSLVDVNQSKDPEGLRTFYYLVQDLKCLVFSLIGLHFKIKPIXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKVELCA FSGFKIYPGHGKKMVRTDGRAFQFINGKCEKSHLMKRNPRKISWTVLYRRKHKKGQTEEV SKKRTKRTTKFQRAITGATLTDIMAKRNQKPEVRKAQREQAIRAAKEKNRAKAAPKPRVG GMRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKVKAKQL RGKKKEDMLKQLDELKTELSQLRVAKVTGGAASKLSKIHVVRKSVARVLTVIHQTQKENL 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QHTKTTGRRGRTVGVSKKK-SGTESDSDDSAPELEDMAQAAGLGEELTSKAKQSRSEKKA RKAMSKLGLKQVQGVTRVTIRKAKNILFVINRPDVYKSPASDTYIVFGEAKIEDLSQQAQ MAAAEKFKAEEEIDETGIEAKDVELVMSQANVSRSKAVRALKNNQNDIVNAIMMGRVRTK TIKKASRVIIEKYYTRLTLDFHTNKRICEEIAIIPSKKLKNKIAGFVTHLMKRIQKGPVR GISIKLQEEERERRDNFVPETSAIEEVDADTKEMLKMLDMANIPGLQVTQPMAGTMRWEY KEEHTFEKRRAEGEKIRKKYPDRVPVIVEKAPKARVGDLDKKKYLVPSDLTAGQFYFLIR KRIHLRPEDALFFFVNNVIPPTSATMGALYQEHHEEDYFLYIAYSDESVYGMRELRIMKL CLNICVGESGDRLTRAAKVLEQLTGQQPVFSKARYTVRSFGIRRNEKIAVHCTVRGSKAE EILDKGLKVREYELRRNNFSQTGNFGFGIQEHIDLGIKYDPSIGIYGMDFYVVLGRPGFS VPHRRKRHASLGAAHRINKEESMKWFQQKYDGVILPGKXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQNERAFQKQPTVFLNKKKTL-PRYVR SVGLGFKTPREAVEGHYIDKKCPFTGNVSIRGRILTGVVLKTKMQRTVVVRRDYLHYVRK YNRFEKRHKNISAHCSPCFRDITIGDVVTMGECRPLSKTVRFNVLKVTKGTGSKKGFSKF MVNVPKSRKTFCKGKKCRKHTLHKVTQYKKGRDSLYAQGKRRYDRKQSGYGGQTKVIFRK KAKTTKKIVLKMECFECKYRKQLPIKRCKHFELGGDRKKKGQMIQFMGRVIRSQRKGAGS VFKAHTKNRKGKACLRAVDYAERHGYIKGVIKDIIHDPGRGAPLAKVAFRDPYKYKLRME TFIAAEGMFTGQFVYCGRKATLQVGNIIPVGSMPEGTIVCCLEEKMGDRGRMARASGNYA TVISHNPDTKRTRVKLPSGSKKVIPSANRAMVGIVAGGGRIDKPMLKAGRAYHKYKVKRN CWPKVRGVAMNPVEHPHGGGNHQHIGKASTVRRDTSAGRKVGLIAARRTGRLRGSKQLTG KXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGRRPARCYRYCKNKPYPKSRFCRGVPDS KIRIFDLGRKKANVDDFPLCIHLVSDEWEQISSEALEAGRICANKYLVKHCGKDAFHLRV RLHPFHIVRINKMLSCAGADRLQTGMRGAFGKPQGTVARVKIGQVILSVRVRDQHREKVV EALRRAKFKFPGRQKIYGSSKWGFTKWQRADFPGMRASGALVPDGVGVQYRPNKGPLIRW KNAQRVTKVIGRTGSQGQCTQVRVEFLDESSRSIIRNVKGPVREGDILTLLESEREARRL RMTKGTSSFGKRHNKTHTLCRRCGGRCYHIQKKTCSRCGYPAARMRKFNWSEKACRRRTQ GVGRMRHMKKVFRRFRNGFQEGTVPKKRVAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGAYKYMQELSRKKQCDVMR FLLRVRCWQFRQLAGIHRASRPTRPDKARRLGYKAKQGFVIYRIRIRRGGRKRPVPKGQV FGKPVHHGVNELKNQRSLQAVAEERVGRRCKALRVMNSYWVGQDSTYKFFEVILVDPFHK AVRHDPKTQWICKPVAKHREMRGLTSASKKSRGLGHGHLFNMTKGGSRRACWRRNNTQQM HRKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGKSSKMLQHINYRMRCTL QDGRTFIGTFKAFDKHMNLILGDCDEFRRVKPK-GKTREEKRVLGLVLLRGENLVSMTVE GPPPAEEGIARVPLPGG-AGPGLGRAAGRGVPMGGGLQGPVRGVGGPSQQHMQPG--MMR GGPPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNDGIKQYYVSKIEDLQLVVTDKTQN LRRLEAQRNELNAKVRMLREELQLLQEQGSYVGEVVKPMDKKKVLVKVHPEGKFVVDLDK NIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYDMVGGLDKQIKEI KEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQ KFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRLESGSGGDSEVQRTMLELLNQLD GFEPKQNIKVIMATNRIDILDSALLRPGRIDRKIEFPAPNEEARLDILKIHSRKMNLTRG INLRKIAEMMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFELAVAKVMQKDSEKNMSI KKLWKLGFAENFALSGAAAVISKTAAAPIERVKLLVQNQDEMIKQGRLDKPYKGVVDCTV RTFRSEGVLPFWRGNLANCLRYFPTQALNFAFKDKIKIMFKMSKTDSYAVKFSKNIASGG FAGAMSLCFVYSLDYARTRLANDAKAGKKRQFSGLVDVYRQTLKTDGFVGLYRGFVISCV GIIVYRGCYFGFYDSLKPIVLGEDAGLLLSFALGYVVTITSGLISYPIDTIRRRMMMTSG EAVKYKGSVDCAIQVIKGEGFMSLMKGAGANILRGVAGAGVLAGFDKFKEVYIAYRLXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSIGV PIKVLHEAEGHVVTCETTTGEVYRGKLVEAEDNMNCQMASITVTYRDGRVAQLENVFIRG SKIRFLILPDMLKNAPMFKRVGAGRGKSAILRAAARGRGRGASSSGPGAMQNEAGEFVDM YIPRKCSASNRIIHAKDHAAIQINLADVDESTGRMTGQYKTYAICGTIRRMGESDDCINR LAKKDSIIGKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGTKDDEY DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTA GQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADNNIVIMLVGNKSDL RHLRAVPTDEAKAFAEKNMLSFIETSALDSTNVETAFQNILTEIYKIVSQKQIRDSPDDN NVQTITVAPTDNSGPGKKPCCNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMVAAKKSKK SIESINSRLALVMKSGKFVLGYKQTLKTLRQGKAKLVIIANNTPPLRKSEIEYYAMLAKT GVHHYNGNNIELGTACGKYFRVTTLSITDPGDSDIIRSMPS-XXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXMGDRYNIHSQLEHLQSKYIGTGHADTNKWDWL TNQHRDSFSSYLGHFDMVNCFAVVENEAKARVKFNLMEXMLQPCGPPPEKPEDMKIELCN YSGYKIYPGHGKKVVKTDGRALTFLCGKCEKSHAMKRNPREINWTVLYRRKHKKGMQEEV TKKRTRRTTKFQRAITGASLTDIMAKRNQKPEVRKAQREQAIRAAKEKQKAKDSSKPRVG GKRMKLNISYPATGCQKMIEVDDEHKLRPFYEKRMSHEMPADHLGDEWKGYVVRISGGND KQGFPMKQGVLTNGRVRLLLSVGHSCYRPRRNGERRRKSVRGCIVDSNLSVLNLVIVKKG EQELPGLTDSTVPRRLGPKRASKIRKLFNLSKEDDVRQYVVRRPLPAQTKAPKIQRLVTP LVLQHKRRRMALRKKRGTKKREDAADYAKLLAQRMKEAKERKMERRRSASHSKKVKAKDL RGKKRDDLTKQLDELKVELSQLRVAKVTGGAASKLSKIRIVRKSIARVMTVIHQTQKENL RKYYIPKDLRPKKTRAMRRLLTPYEKSLKTSKQERRLRSFPPRVYALKXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKKKKISLTFTVD CTHPVEDGILDVAAFETFLNERIKVQGKTKNFKTKLVVRASIPFSKRYLKYLTKKFLKKN NLRDWLRVVARDKDSYELRYFQINNEEDEEDDDNXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLKQITLDELKAHNTARALWLAIHDKVYDVT KFIDPHPGGEEVIVESAGKYTTEAFEDVGHSTDARDLMKDYLIGELVEEARGSLSSWLIP LGIAIAAALLYKFIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXPRRVQTLVDDLKNVEFETSEDVEVTPTFDGLGLREDLLRGIYAYG FEKPSAIQQRSIRPIVKGRDVIAQTQSGTGKTATFSISILQSLDTQVRETQALVLSPTRE LAQQIQKVILALGDYMSVQCHACIGGTNVGEDIRKLDYGQHVVSGTPGRVFDMIRRRNLR TRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVCLISATLPHDILEMTSKFMTDPI RILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKXDWLTEKM REANFTVSSMHGDMPQKEREAIMKEFRSGSSRVLITTDVWARGLDVQQVXLVINYDCP-H RELYI-------------------------------------------------XXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXTAPFDARFPNVNQTRNCWQNYVDFHRCHKIDDYE PCNYFQRVYKSLCPSEWTDKWDDQMENGAFAGKIXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMGKEKIHINIVVI GHVDSGKSTTTGHLIYKCGGIEKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITI DICLWKFETPKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKNGQT REHALLAFTLGVKQIIIGVNKMDNTEPPYSEQRFNEIKKEVEAYIKKIGYNPKGVPFVPI SGWHGDNMLNMKWFTGFNIVDGVTLMNALDAIDPPSRPTDRPLRLPLQDVYKIGGIGTVP VGRVETGIIKPGVVVTFAPCNLTTEVKSVEMHHTSLPEAVPGDNVGFTXQNVSVKEIRRR VCCWRFPDDPPKAT-ETSGQVII------------------------------------- ------------------------------------------------------------ ---------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPKQ IMEIKDFLLTARRKDAKSVKIKKNVKFKVRCSRYLYTLVISDLEKADKLKQSLPPGLSVK ELKMSKLSRETVTDAVNEVLAKRRRFTETVELQISLKNYDPQRDKRFAGTVKLRHIPRPR MNVCILGDQQHCDEAKAQDIPCMDADSLKKLDKNKKLVKKLAKKYKAFLASDTLIKQIPR ILGPGLNKAGKFPTILSHSDSMTGKIDEVKATIKFQMKKVPCLAVALGHVKMTPEQLSNN IILAVNFLVSLLKKNWQNVRALYVRAPWVPL----XXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXMTDPTIQNLQDPFAEDEGIHIRIQQRNGRKTLTTVQGISPEFDLKKI VKIAKKEFACNGTVVDHSEYGEVIQLQGDQRQPISGFLKRVGLDEQIKVHGFSALFNFQS LLTVVLLLICTCAYIRSIAPRLLDKNKEGLLGIFWKCARIGERKSPYVAVCCIAMAFSIL FLTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX METIYSAPFSLLECPNLKLKKPSWVKTPSAMFMFALVLLSYFMVTGGIIYDVIVEPPSIG STTDEKGNSKPVAFMPFRVNGQYIMEGLASSFLFTLGGLGFIVLDQTNKPTTPRLNRILL FCLAFLSILISFFMCRVFIRMKLPMPKVKRSRKPPPDGWELIEPTLDELDQKMREAETDP HDGKRKVEALWPIFRLHHQRSRYIFDLFYKRKAISRELYEYCLKENIADKNLIAKWKKPG YENLCCLRCIQTRDTNFATNCVCRVPKPKLEEGKIVECVNCGCRGCSGXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXLVRFLMKLSHETVTIELKNGTQVHGTITGVDVSM NTHLKSVKMTIKNRDPVQLDTLSIRGNNIRYFILPDSLPLDTLLIDDAPKSKARGXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPIVIDGRGHLLG RLSAIVAKTILQGQRVVVVRCEGINISGNFYRNKLKYLDFLRKRHNTNPKRGPYHFRAPS KIFWRTVRGMLPHKLHRGKEALERLKCFEGIPAPYDKQKRMVVPSALKVLRLKSRRKFCN LNRLSHEVGWKYQNVVATLEARRKLKSAKYYKAKMAEKKLRSQALKVQKQTKVIEAFGYX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFEAR LVQGSLLKKVLEAIKDLLNEAKWDCNEHGMSLQAMDSSHVSLVSLLLRSDGFDTYRCDRN FSMGINLTSMSKILKCAANDDAITIKTNDNADTVTYMFESQSGDKVSDYEMKLMDIDADH LGIPETDYSCIVKMPAAEFQRICRDLSQVGESVVICCTKEGVKFSASGDLGTGNIKLAQT ANVDKEEEAVTIEMQEAVSLTFALRYLNFFTRATPLSPQVSLSMSAEVPLGCGIQNRDMG HIRYYLAPKL------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXMLMPKKNRVAIYEYLFKEGVMVAKKDVHAPKHPDLEVPNLHVI KCLQSLKSRGLVKEQFAWRHYYWYLTNEGIQYLRDFLHLPPEIVPATLKRQRMGEDRAAY RKGGGMDKKADAGAGANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX MTNTKGYRRGTRYLFSRAFKTKGVIPLSTYFRTYKRGDIVDIKGNGAVQKGMPHKIYHGR TGRVYNVTQHALGVIVNKRVRGNIIAKRINVRVEHVKHSQCRKDFTDRMAKNEARKQEAK KRINFKRQPAQPIGGHFVSTRYNKPEVLEPVKWEFIAXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXKKLTKAEELLLQDFSRNVSTKSSALFYGNAFIVAAIPIWLFWR IHQMDLLAIFAIMTVLSTYLVAYAYKNLKFLLKHKIALKRGEAVSREVMRNVEGDKKMSK QEKEERILWKKNEVADYEATTFSIFYNNALFLLLVVFCSFYVLKTFSPTVNYMLSMGIAS GLLALFSTSTKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXMAEYLASIFGTEKDKVNCSFYFKIGACRHGERCSRLHNKPTFSQTMLLQN LYINPQNTAQINLTDTEAQELFDDFFEEVFTELEDKYGEIEEMNVCDNLGDHLVGNVYVK FRSEESAEKACQELNNRWFNGRPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKP ISRELRRELYGRSRRHKSRSPPTRRSRSRER---RRRSRSRDKK-MFLTRSEYDRGVNTF SPEGRIFQVEYAIEAIKLGSTAIGIQTVDGVVLAVEKRVTSPLIEPSSIEKIMEVDSHIG CAMSGLIADSRTMIDRARVEAQNHWFTCNEKMSVESVTQAVSNLALQFGDDDADPGAMSR PFGVALLFAGIDDKGSQLFHMDPSGTFIQYDAKAIGSGSEGAQQALQETYHKSMTLREAA KESLKILKQVMEEKLNSTNVEMAKVTPSEGFKIFSKEELEEVIKEIXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDSGREKCLQDYRKKLLEHKELEARLKEMRE QLKDLTKQYDKSENDLKALQSVGQIVGEVLKQLTEDKFIVKATNGPRYVVGCRRQIDKSK LKSGTRVALDMTTLTIMRYLPREVDPLVYNMSTEDAGDTSYSEIGGLSEQIRELREVIEL PLLNPELFLRVGITPPKGCLLYGPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIGES ARLIREMFGYARDHQPCIIFTDEIDAILKVPLLIEKSREL---LWELLNQMDGFDSLGQV KMIMGTNRPDTLDPALLGPGRLDRKIEIPLPNEQA------------------------- --------------------------------------------------------XXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXVIDHYENPRNVGSMDKKDKFVGTGLVGAPACGDVMKLQIKVDEEG KIVDAKFKTFGCGSAIASSSLATEWVKGKSVDEAAAIKNTEIAKELCLPPVKLHCSMLAE DAIRAALNDYKTKNQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXMGKFMKSGKVVLVLAGRYAGKKAIIVKNYDDGSSDKQYGHALVA GISRYPRKVTKRMGKKKIKQRSKVKSFLKVVNFNHLMPTRYSVVNFDKQVVNKDAFRDPA LRKKARSDIKARFEERYKTGKNRWFFQKLRFERSFIMIKPDGVHRGLVGDIIKRFEAKGF KLVAMKFMWASEELLQKHYADLSARPFFAGLVKYMSSGPVVPMVWEGGVVKTGRVMLGET DPAQSLPGTIRGDYCIEVGRNICHGSDAVESANKEIELWFGK-DVVSWKPCSEDWIYEPA APKPVKSDGAGKDKALSAKRAVLKGNRDKRSRKVRTSVHFRLPKTLKLPRAPKYPRRSTF KEPRLDQFKIVKYPLTTESAMKKIEDNNTLVFIVNKLANKPQIKMAIKKLYDIDVSKVNT LNRPDGEKKAYVRLAPDYDALDVANKIGIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMIRFI LIQNRAGKTRLAKWYMHFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIVYRRYAGL YFCICVDVADNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYSVVDEMFLAGEIRE TSQTRVLKQLLMLSSLEGDTIFGKIIRGEIPSKFIYEDEKSVAFHDVSPQAPVHFLVLPK RPITQLSADEELLGHLLGVARQVAKQESGYRLVINDGPNGAQSVYHLHIHVMGGRQMSWP PXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXRLYAKAVFTGFKRGLRNQHENTALIKIEGVTTKNDTEFYLGKRCCYVYKA KTKTACPGHEKASRIRVIWGKVTRPHGNSGSVRATFRRNLPPKAMGRRIRVMMYXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPQNEHIEQHIKR HGRRLDYHEKKRKKESRQAHEVSHKAKKLRGIKAKLYNKKRHSEKIQMKKTLKTHEERKT RQRSEDNVPEGAVPAYLLDRQEQTRAKVLSNMIKQKRKEKAGKWDVPLPKVKGMSEAEVF KVVKTGKTRRKGWKRMVTKACFVGEGFTRKPPKYERFIRPMGLRFKKAHVTHPELKATFC LPIIGVKKNPTSPLYTSLGVITKGTVVEVNVSELGLVTQGGKVVWGKYAQVTNNPENDGC INAVLLVMAARPLITVHSDKGAASESNVTLPAVFRAPIRPDIVNFVHFELKKNGRQPYAV SQKAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRR VNTTQRRHALVSAIAATGIPAVVMSKGHCIEQIPEVPLVVSDSVESIKKTKEAVVVLRRL KAWPDVEKVKNSRRFRAGKGKMRNRRRIQRRGPLIIYGTDNGISRAFRNIPGITLVNVNR LNLLSMAPGGHVGRFCIWTESAFKQLDNIYGTWKRPSAEKSHYNLPMPKMTNTDLSRLLK SDEIQNALREPKK----------------------------------------------- -----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------QMRTT INRKLVETGERERLKELLRQRLIECGWRDELKAYCKEVVRQKGLEHITVDDLVSEITPKG RSLVPDQVKKELLQRIRSFLAQQSNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXMAHTILLVQPGRKPETRTYSDYESINECLEGVCKIYEEYLKRTNPTSASITYDIKN LFNFIDQLADLSCLVFEQSSAKYVPHNKAWIKEKIYHLLKKQAGKXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMSHRKFSAPRHGSLGFLPKKRSRRHRGKC KAFPKDDPTKPVHLTAFVGYKAGMTHVVRDVDRPGSKAHKKEVVEAVTILETPPLVVVGV VGYIETPKGLRTFKTIWAEHLGEECRRRFYKNWYCSKKKAFTKASKKWQDEQGKREIEKD FAKMKRYCAVIRVITHTQMKLMKKRQKKAHIMEIQLNGGTVPQKVDWAREHLEKQLAVEN VFAQDDYIDVIGITKGKGFKGVTSRWNTKKLPRKTHKGLRKVACIGAWHPARVSFSVARA GQKGYHHRTEINKKIYRIGKGVRSEFGKVVKNNASTEADITEKTITPMGGXPHYGEVMRT 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